PMID int64 27.8M 36.2M | Title/Abstract stringlengths 7 10.7k | MeshTerms stringlengths 7 104 | SemanticTypes stringlengths 4 84 |
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34,673,014 | chrysin induc autophagi depend ferroptosi increas chemosensit gemcitabin target cbr pancreat cancer cell recent studi verifi induc reactiv oxygen speci ros one gemcitabin anti tumor mechan action human carbonyl reductas cbr play import role protect cell oxid damag howev unclear whether cbr involv pancreat cancer pc progress resist gemcitabin base gepia databas analyz tumor tissu sampl pc patient use immunohistochemistri ihc reveal cbr high express pc tissu signific correl clinicopatholog featur pc genet inhibit cbr suppress pc cell prolifer regul ros generat furthermor gemcitabin upregul cbr express could limit anti tumor activ gemcitabin attenu cbr enhanc gemcitabin sensit vitro vivo addit report chrysin direct bind cbr inhibit enzymat activ molecular cellular level inhibit cbr chrysin increas cellular ros level led ros depend autophagi result degrad ferritin heavi polypeptid fth increas intracellular free iron level particip ferroptosi pc cell final result show chrysin enhanc pc sensit gemcitabin induc ferroptot death vitro vivo collect find indic cbr potenti therapeut target pc treatment addit elucid novel mechan under anti tumor effect chrysin | D019008 | T042;T038 |
34,673,013 | cyclin depend kinas potenti target lycorin hepatocellular carcinoma patholog chang possibl under molecular mechan hepatocellular carcinoma hcc current unclear effect treatment patholog state remain challeng purpos studi obtain key gene diagnost prognost mean identifi potenti therapeut agent hcc treatment cdk ccnb ccnb found high express hcc patient accompani poor prognosi knockdown sirna drastic induc autophagi senesc hepatoma cell simultan anti hcc effect lycorin compar interf three gene lycorin signific promot decreas protein mrna express cdk molecular valid mechanist demonstr lycorin might attenu degrad rate cdk via interact confirm cellular thermal shift assay drug affin respons target stabil assay taken togeth find suggest cdk ccnb ccnb could regard potenti diagnost prognost biomark hcc cdk might serv promis therapeut target lycorin hcc | D016503 | T074 |
34,673,012 | impact altern splice mechan resist anticanc drug share characterist mani tumor lack respons anticanc drug multipl mechan pharmacoresist mprs involv permit cancer cell overcom effect agent pharmacoresist primari intrins secondari acquir ie trigger enhanc respons treatment moreov mprs usual result lack sensit sever agent account divers multidrug resist mdr phenotyp mprs base dynam express one hundr gene constitut call resistom altern splice pre mrna matur result chang affect protein involv resistom result splice variant svs reduc efficaci anticanc drug lower intracellular level activ agent alter molecular target enhanc dna repair abil defens mechan tumor induc chang balanc pro surviv pro apoptosi signal modifi interact tumor microenviron favor malign phenotyp transit reason account cancer associ aberr splice includ mutat creat disrupt splice site splice enhanc silenc abnorm express splice factor impair signal pathway affect activ splice machineri review impact mpr cancer cell | D017398 | T114;T045;T123 |
34,673,008 | nanostructur lipid carrier encapsul phloretin prepar vitro character studi phloretin power antioxid mani effect anti cancer anti inflammatori promot cell renew delay age howev applic phloretin limit low water solubl low absorpt vivo unstabl properti phloretin load nanostructur lipid carrier design high pressur homogen techniqu mean particl size phloretin nlc nm polydispers index pdi valu encapsul effici transmiss electron microscopi imag show phloretin load nanostructur lipid carrier spheric phloretin nlc show sustain releas pattern vitro result show phloretin nlc suitabl absorpt phloretin ethanol solut nlc promis carrier phloretin food industri | D004337;D049329 | T122;T073 |
34,673,007 | eus guid transhepat biliari drainag larg singl center us experi eus guid hepaticogastrostomi perform mani year publish experi outsid unit state lumin access point esophagus stomach duodenum jejunum biliari access either right left intrahepat system thus prefer term eus guid transhepat biliari drainag etbd describ believ largest singl center us experi etbd manag benign malign biliari diseas | D001662;D018084 | T060;T061 |
34,673,005 | evalu bacteri colon clinic properti differ sutur materi dentoalveol surgeri studi aim compar effect differ sutur materi common use dentoalveolar surgeri wound heal postop microbi colon relat clinic paramet | D019647;D013537;D014945 | T040;T074;T061 |
34,673,004 | leptospira collagenas lipl antibodi detect leptospirosi various leptospira compon identifi candid antigen detect antibodi leptospira lipl leptospira membran protein wide studi report leptospira whole genom sequenc demonstr pathogen leptospira contain nucleotid sequenc cola gene code collagenas express cola protein enzymat activ demonstr studi clone cola protein comparison lipl use antigen antibodi detect thirti pair sera human leptospirosi patient test sera blood donor patient scrub typhus dengu virus infect sampl group test specif sera leptospirosi patient test studi react cola lipl protein sera blood donor patient scrub typhus dengu virus infect react cola protein data suggest sensit specif cola protein leptospira antibodi detect addit cola protein show higher specif lipl data suggest cola protein could anoth candid antigen antibodi detect leptospirosi diagnosi | D007159 | T059 |
34,672,994 | neonat invas candidiasi updat clinic manag prevent neonat invas candidiasi import caus morbid mortal preterm infant incid invas candidiasi popul declin high incom set larg due prevent measur although still consider variat incid health care centr surveil data larg multicentr studi lower incom set avail although prevent measur set shown decreas incid neonat invas candidiasi understand risk factor pathogenesi key prevent invas candidiasi difficulti definit diagnosi invas candidiasi high risk death substanti neurodevelopment impair even appropri treatment increas need effect prevent measur review examin pathogenesi clinic present diagnosi invas candidiasi highlight common use emerg prevent prophylact measur includ standardis central line care antibiot stewardship antifung prophylaxi probiot final provid updat empir treatment clinic manag confirm case invas candidiasi antifung pharmacotherapi | D000073602;D058365;D007234;D019936 | T100;T007;T047;T058;T033 |
34,672,993 | evid base framework determin optim amount intervent autist children provis time effect social valid non pharmacolog intervent core effort support develop young autist children effort intend support children develop skill empow caregiv lay foundat optim choic independ qualiti life adulthood optim amount intervent viewpoint review current guidelin consid evid umbrella review non pharmacolog intervent autist children age year show lack consensus issu identifi factor might relev consid present evid base framework determin optim amount intervent child along recommend futur research | D032921 | T054 |
34,672,991 | anteced outcom persist remit adolesc depress symptom trajectori longitudin popul base english studi depress often first emerg adolesc mani lifelong disord long term clinic cours depress high variabl aim examin adult outcom adolesc onset trajectori clinic signific depress symptom identifi factor differenti trajectori persist desist adulthood | D000297 | T091 |
34,672,989 | seropreval listeria monocytogen hiv infect pregnant women brazil describ preval factor associ serolog respons listeria monocytogen hiv infect uninfect pregnant women brazil | D015658;D008089 | T007;T047 |
34,672,988 | insight epidemiolog communiti associ methicillin resist staphylococcus aureus special popul communiti healthcar interfac current epidem proport infect caus staphylococcus aureus strain especi methicillin resist aureus mrsa one today mani threat global public health particular underdevelop countri signific gap subject exist rapid spread diversif pandem clone exhibit remark increas virul antimicrobi resist pose risk effect prevent treatment wide rang infect undoubt remark versatil involv pathogenesi resist bacteria perpetu geograph tempor factor inher clonal evolut reflect dramat epidemiolog chang mrsa decad prevail healthcar set emerg communiti denomin communiti associ ca mrsa strain particular preval popul group facilit spread success clone potenti capabl trigger sever communiti acquir infect therefor broad approach local epidemiolog aspect less studi region nonetheless latent risk endem spread may reach global proport necessari brazil despit limit molecular epidemiolog data ca mrsa strain predomin character sccmec iv often classifi cc st cc st cc st seem spread across differ popul group differ region countri anoth import fact address review identif st mrsa ivv clone methicillin suscept aureus mssa healthi individu communiti although suscept methicillin st clone associ sever infect human anim denomin livestock associ mrsa therefor import encourag assert action govern sector societi reassess current public health measur light new perspect aris scientif epidemiolog data mrsa | D017714;D055624;D013203 | T007;T047 |
34,672,987 | dystonia specif mutat thap alter transcript gene associ neurodevelop myelin dystonia neurolog disord associ increas larg number genet variant mani gene result characterist disturb volit movement dissect relationship mutat function outcom critic understand pathway drive dystonia pathogenesi establish pipelin character allel seri dystonia specif mutat use strategi investig molecular consequ genet variat thap encod transcript factor link neural differenti multipl pathogen mutat associ dystonia cluster within distinct thap function domain predict alter dna bind properti andor protein interact differ yet relat impact vari chang molecular signatur neural deficit unclear determin effect mutat thap transcript activ engin allel seri eight alter common induc pluripot stem cell background differenti line panel near isogen neural stem cell n line transcriptom profil follow joint analysi robust signatur across mutat identifi converg pattern dysregul gene function relat neurodevelop lysosom lipid metabol myelin basi observ examin mice bear thap disrupt allel detect signific chang myelin gene express reduct myelin structur integr relat control mice result suggest deficit neurodevelop myelin common consequ dystonia associ thap mutat highlight potenti role neuron glial interact pathogenesi dystonia | D009154 | T045 |
34,672,986 | interocept breath relationship anxieti interocept percept intern bodili state thought inextric link affect qualiti anxieti although interocept span sensori metacognit process clear whether anxieti differenti relat process level investig question domain breath use comput model high field fmri assess brain activ relat dynam chang inspiratori resist vari predict notabl anterior insula associ breath relat predict certainti predict error suggest import role repres updat model bodi individu low versus moder anxieti trait show differenti anterior insula activ predict certainti multi modal analys data fmri comput assess breath relat metacognit questionnair demonstr anxieti interocept link span level perceptu sensit metacognit strong effect seen higher level interocept process | D065812 | T041 |
34,672,985 | brain rhythm defin distinct interact network differenti depend anatomi cognit function subserv rhythmic neuron synchron across wide distribut brain area area pair investig function connect fc coher power correl granger causal gc theta beta high beta gamma rhythm rhythm spatial fc pattern larg independ thus rhythm defin distinct interact network import network coher gc explain spatial distribut strength rhythm network particular gc network contain clear modul typic one domin rhythm per modul understand distinct modular aris common anatom backbon correl across area pair metric function interact anatom project strength anatomi primarili relat coher gc largest effect size gc correl differ mark rhythm less pronounc beta strongest gamma rhythm | D001921;D065818 | T023;T042 |
34,672,984 | chemogenet sensori fmri reveal behavior relev bidirect chang primat somatosensori network concurr genet neuromodul function magnet reson imag fmri primat provid valuabl opportun assess modifi brain wide oper rest state howev applic link network oper behavior still remain challeng combin chemogenet silenc primari somatosensori cortex si tactil fmri relat behavior macaqu focal chemogenet silenc function identifi si hand region impair grasp behavior silenc also attenu hand stimul evok fmri signal local silenc site anatom andor function connect downstream grasp network suggest alter network oper under induc behavior impair furthermor hand region silenc unexpect disinhibit foot represent accompani behavior hypersensit result demonstr focal chemogenet silenc sensori fmri macaqu unveil bidirect network chang generat multifacet behavior impair therebi open pivot window toward elucid causal network oper underpin higher brain function primat | D005821;D018737;D014110 | T040;T062;T042;T081 |
34,672,982 | domain specif versus process specif social brain strateg interact social brain respons domain specif domain general social preval cognit process drive activ network issu neuron konovalov et al address dissoci general social reactiv one defin featur social interact | D001921;D012919 | T023;T054 |
34,672,981 | mir step threshold motor impair issu neuron amin et al generat genet tool titrat level mir motor neuron enrich microrna vivo vari mir dose alter target select result distinct dose respons curv reflect utr featur reveal mir threshold motor neuron deficit emerg | D035683;D000068079 | T047;T114;T123 |
34,672,980 | uncov harbing human brain evolut evolut human acquir extens genom chang collect defin uniqu featur speci yet function sequenc variant larg unknown issu neuron girski et al comprehens screen human acceler region har enhanc activ human specif cortic develop creat valuabl onlin resourc | D016678;D023281 | T091;T028 |
34,672,979 | share care benefit distribut protein aggreg among microgli network traffick protein aggreg neural circuitri caus advers outcom includ propag patholog toxic neurodegen diseas recent issu cell scheiblich et al describ advantag aggreg share strategi microgli network nurtur synuclein load member back health | D017628;D019636 | T025;T047 |
34,672,978 | kay tye kay tye share focus person team mental physic health form necessari foundat futur success interview neuron also discuss need better represent stem global lockdown reinvigor scientif interest social homeostasi | D009488;D014931;D000072358 | T091;T033;T056;T098 |
34,672,976 | eunji cheong korea pandem elev scientist trust sourc polici decis dinner tabl convers interview neuron eunji cheong discuss need support futur generat foster scientif think patienc flexibl | D009488;D011050;D024382;D013850 | T057;T064;T041;T091;T054;T078 |
34,672,975 | ishmail abdus saboor interview neuron ishmail abdus saboor talk futur team scienc pandem renew faith basic research emphas import human divers scienc fuel innov equal talent need equal opportun | D000075762;D009488 | T091;T062;T090 |
34,672,974 | joni walli neuron q joni walli share experi challeng face tran woman neurosci role model import consid life circumst scientist beyond academ work | D009488;D063106;D000072358 | T091;T033;T056;T098 |
34,672,973 | gregori quirk gregori quirk work new york hondura puerto rico decad long commit mentorship global promot neurosci interview neuron talk upcom move univers philippin virtual meet make us rethink collabor interact member communiti | D003226;D000071252;D008611;D009488;D049269 | T065;T066;T098;T073;T170;T091;T068 |
34,672,972 | shubha tole shubha tole dean graduat studi tata institut fundament research mumbai india share neuron approach mentorship challeng time connect divers perspect across globe make us stronger love art includ classic danc poetri | D000071252;D008611;D009488 | T091;T065;T098 |
34,672,971 | clip microtubul tip variant confer resist taxan impair drug target engag taxan wide use cancer chemotherapeut howev intrins resist limit efficaci without action resist mechan discov microtubul mt plus end bind clip protein variant hereaft clip found enrich taxan resist cell line patient sampl clip lack first cap gli motif form longer comet impair taxan access mt lumin bind site clip knockdown revers taxan resist cell xenograft wherea express led resist suggest causat use comput approach conjunct connect map unexpect discov imatinib predict revers clip mediat taxan resist inde imatinib treatment select deplet clip thus complet revers taxan resist rtk inhibitor also deplet clip suggest class effect herein identifi clip clinic preval variant confer taxan resist wherea discoveri imatinib clip inhibitor provid novel therapeut opportun futur trial | D017353 | T045 |
34,672,963 | effect chang vaccin schedul pertussi epidemiolog franc model serolog studi april may franc modifi pertussi vaccin schedul use acellular pertussi vaccin three primari dose month age first booster month age former schedul two primari dose month age first booster month age new schedul aim assess subsequ effect vaccin schedul chang pertussi epidemiolog franc | D022681;D014917 | T129;T047;T121 |
34,672,960 | non prefer contrast respons drosophila motion pathway reveal recept field structur explain common visual illus divers sensori system audit thermosens featur separ input increment decrement signal drosophila visual system separ pathway comput direct motion yet anatom function studi identifi crosstalk channel use well studi circuit ask whether motion comput depend pathway crosstalk use whole cell electrophysiolog record visual respons cell map composit recept field found share similar spatiotempor structur fit biophys model recept field accur predict direct select respons move stimuli model also provid detail mechanist explan direct prefer invers respons promin revers phi illus final use steer respons tether fli fli valid model predict effect vari stimulus paramet behavior turn invers | D007088;D009039 | T033;T048;T041 |
34,672,959 | decif subclon composit tumor accur identifi subclon make tumor critic understand cancer biolog articl issu cell system sata et al examin mutat evolutionari perspect deciph composit tumor | D009369 | T191 |
34,672,958 | decompos mutat landscap cancer genom repairsig mutat signatur outcom mutagen process occur prior tumorigenesi result dna damag dna repair dna replic issu cell system wojtowicz et al introduc new comput model aim deconstruct mutat process shape cancer genom | D009369 | T191 |
34,672,957 | pave path toward genom privaci secur imput ensur privaci particip genom studi critic respons biomed communiti accur effici implement secur genotyp imput highlight practic approach safeguard sensit genom data adapt numer bioinformat applic | D023281;D018907 | T091;T033;T089 |
34,672,956 | protein matchmak represent learn sledzieski singh cowen berger employ represent learn predict protein interact associ addit identifi bind residu protein pair generaliz showcas train one organ evalu other work exemplifi transfer ai learn represent advanc knowledg molecular biolog | D019359;D000069550 | T170;T066 |
34,672,955 | democrat long read genom assembl de novo assembl genom serv backbon modern genom articl issu cell system ekim et al present mdbg assembl assembl genom fold faster previous method includ human genom min unlock pan genom mani speci | D023281;D059014 | T091;T059;T063 |
34,672,953 | vitro system silenc mitochondri gene express human mitochondri genom encod thirteen core subunit oxid phosphoryl system defect mitochondri gene express lead sever neuromuscular disord howev mechan mitochondri gene express remain poor understood due lack experiment approach analyz process present vitro system silenc translat purifi mitochondria vitro import chemic synthes precursor morpholino hybrid allow us target translat individu mitochondri mrnas appli approach conclud bicistron overlap atpatp transcript translat singl ribosomemrna engag show recruit cox assembl factor translat ribosom depend nascent chain format defin mrna specif interactom cox cox reveal unexpect function cytosol oncofet igfbp rna bind protein mitochondri translat data provid insight mitochondri translat innov strategi investig mitochondri gene express | D005786;D020868;D050259 | T028;T045 |
34,672,952 | map genet landscap dna doubl strand break repair cell repair dna doubl strand break dsbs complex set pathway critic maintain genom integr systemat map pathway develop high throughput screen approach call repair seq measur effect thousand genet perturb mutat introduc target dna lesion use repair seq profil dsb repair product induc two programm nucleas cas casa presenc absenc oligonucleotid homolog direct repair hdr knockdown gene involv dsb repair associ process result data enabl principl data driven infer dsb end join hdr pathway systemat interrog data uncov unexpect relationship among dsb repair gene demonstr repair outcom superfici similar sequenc architectur mark differ genet depend work provid foundat map dna repair pathway optim genom edit across divers modal | D053903;D023281 | T049;T091 |
34,672,950 | colchicin patient admit hospit covid recoveri randomis control open label platform trial colchicin propos treatment covid base anti inflammatori action aim evalu efficaci safeti colchicin patient admit hospit covid | D000086382 | T047;T067 |
34,672,949 | efficaci interferon beta plus remdesivir compar remdesivir alon hospitalis adult covid doubl bind randomis placebo control phase trial function impair interferon natur antivir compon immun system associ pathogenesi sever covid aim compar efficaci interferon beta combin remdesivir compar remdesivir alon hospitalis patient covid | D000086382 | T047;T067 |
34,672,948 | explor pluripot space chart cell state transit peri implant develop pluripot cell mammalian embryo undergo state transit mark chang pattern gene express development potenti progress pre implant post implant stage develop recent studi cultur mous human pluripot stem cell hpscs identifi cell repres intermedi stage refer format state naiv pluripot equival pre implant epiblast prime pluripot equival late post implant epiblast examin recent find light knowledg peri implant mous human develop consid implic work deriv human embryo model pluripot cell | D039904 | T025 |
34,672,947 | mechanist insight covid global analysi sar cov cl pro substrat degradom main viral proteas cl pro indispens sar cov replic delin human protein substrat landscap cl pro tail substrat target n terminom identifi substrat human lung kidney cell support analys sar cov infect cell enzym kinet molecular dock simul cl pro engag substrat reveal noncanon cleavag site diverg sar cov guid substrat specif cleav interactor essenti effector protein effect strand bind partner amplifi consequ proteolysi show cl pro target hippo pathway includ inactiv mapk key effector transcript mrna process translat demonstr spike glycoprotein direct bind galectin galectin cleavag disengag calcocondp decoupl antivir autophagi inde post mortem covid lung sampl ndp rare coloc galectin unlik healthi lung cl pro substrat degradom establish foundat substrat atlas acceler explor sar cov patholog drug design | D000086382 | T047;T067 |
34,672,945 | opioid obstruct sleep apnea opioid wide prescrib pain manag estim adult unit state use prescript opioid everi year opioid misus lead high mortal respiratori depress main caus death anim human studi indic opioid use may lead sleep disord breath opioid affect control breath impair upper airway function caus central apnea upper airway obstruct hypoxemia sleep presenc obstruct sleep apnea osa increas risk opioid induc respiratori depress howev even relationship opioid central sleep apnea firm establish question whether opioid aggrav osa remain unansw sever report shown high preval osa nocturn hypoxemia patient receiv high dose opioid studi find correl opioid use obstruct event differ attribut consider interindividu variabl diverg effect opioid differ phenotyp trait osa wide rang methodolog review discuss mechanist insight effect opioid upper airway hypogloss motor activ associ opioid use obstruct sleep apnea | D009293;D012891;D020181 | T048;T047 |
34,672,944 | facilit barrier get obstruct sleep apnea diagnos perspect patient partner obstruct sleep apnea osa preval debilit condit signific underdiagnos major adult sleep someon partner partner play signific role patient osa diagnosi goal work describ facilit barrier osa diagnosi discuss patient osa partner | D020181 | T047 |
34,672,930 | postpartum depress screen treatment engag barrier care chang depress symptom postpartum depress ppd common condit associ childbirth yet mani women receiv treatment need despit grow practic ppd screen treatment clinic outcom among patient identifi like ppd remain unclear | D019052 | T048 |
34,672,929 | artifici intellig aid detect diagnost accuraci mood disord predict suicid risk systemat review mood disord often diagnos clinic interview yet mani case miss misdiagnos mood disord increas risk suicid make imper diagnos treat disord quick artifici intellig ai investig diagnos mood disord merit literatur evalu systemat review aim understand explain ai method evalu use augment clinic diagnosi mood disord well identifi individu increas suicid risk | D001714;D013405 | T033;T048 |
34,672,928 | random control trial symptom anxieti depress effect day accept commit train workshop cognit behavior therapi often recommend anxieti disord howev treatment adher complianc major barrier treatment often deliv session sever month random control trial trial registr nct wwwclinicaltrialsgov examin effect feasibl day cognit behavior intervent mix anxieti | D064869;D015928 | T061 |
34,672,927 | characterist patient deep brain stimul treatment resist depress among inpati major depress disord aim studi evalu characterist patient pattern rate use deep brain stimul dbs major depress disord mdd unit state | D046690;D003865 | T048;T061 |
34,672,926 | psychometr properti general anxieti disord item scale youth screen primari care sampl anxieti disord youth frequent underdiagnos untreat part due lack screen primari care general anxieti disord item gad scale brief self report measur design screen anxieti primari care set howev littl known psychometr scale adolesc | D001007;D001008 | T048;T184;T041 |
34,672,925 | real life contextu exposur therapi use augment realiti pilot clinic trial novel treatment method phobia includ arachnophobia common treat exposur therapi method limit lack fear objectssitu clinic set | D000081411;D007171;D010698;D013112 | T204;T048;T170;T061 |
34,672,921 | rhodocaloribact litori gen nov sp nov isol intertid hot spring red pigment strain non sporeform aerob chemoorganotroph bacteria isol intertid hot spring laugarvk nw iceland cell stain gram negat form pleomorph rod often swollen end occur singl filament growth observ c optimum c ph optimum optimum wv nacl strain iscar contain mk main respiratori quinon satur iso anteiso branch chain carbon main cellular fatti acid gc content dna mol highest rrna gene sequenc similar genus roseithermus follow rhodothermus rubrivirga rubricoccus genom phenotyp comparison support affili novel isol genus roseithermus famili rhodothermacea phylum rhodothermaeota describ isol propos classifi repres novel speci belong novel genus name rhodocaloribact litori gen nov sp nov type strain iscar dsm atcc tsd | D045482;D010802 | T070;T062;T078 |
34,672,920 | catenulispora pinistramenti sp nov novel actinobacteria isol pine forest soil poland taxonom status two filament actinobacteria isol nf nl recov litter layer pine forest soil poland establish genom base polyphas studi isol show combin chemotaxonom morpholog physiolog properti associ classif genus catenulispora form well support lineag within catenulispora rrna gene tree close relat type strain catenulispora acidiphila catenulispora pinisilva catenulispora rubra like found larg genom mbp respect phylogenom tree base draft genom isol nf nl phylogenet neighbour show form distinct branch catenulispora clade close relat c pinisilva dsm isol share combin genom genotyp phenotyp featur high averag nucleotid index ani digit dna dna hybrid dddh similar consist assign speci isol distinguish c acidiphila c pinisilva c rubra strain wealth taxonom data low ani dddh valu propos isol classifi genus catenulispora c pinistramenti sp nov isol nl dsm pcm type strain genom strain nf nl rich natur product biosynthet gene cluster henc strain potenti synthes new specialis metabolit | D039903;D010802;D012988 | T007;T062;T067;T078 |
34,672,919 | treponema peruens sp nov commens spirochaet isol human faec gram stain negat obligatori anaerob spirochaet rcc isol faecal sampl obtain individu resid remot amazonian communiti peru bacterium show highest rrna gene sequenc similar pig intestin spirochet treponema succinifacien averag nucleotid ident valu strain rcc avail treponema genom valid type strain thus clear lower speci delin threshold dna gc content rcc mol phenotyp character use api zym api system confirm diverg posit bacterium within genus treponema strain rcc could differenti phylogenet close relat succinifacien presenc alkalin phosphatas glucosidas activ unlik succinifacien strain rcc grew equal well without serum strain rcc first commens treponema isol human faecal microbiota remot popul base collect data repres novel treponema speci name treponema peruens sp nov propos type strain rcc lmg cip | D005243;D010802 | T062;T031;T078 |
34,672,916 | paenibacillus allorhizosphaera sp nov soil rhizospher zea may gram stain posit aerob endospor form bacteri strain isol rhizospher zea may studi detail taxonom alloc base rrna gene sequenc similar comparison strain jj shown member genus paenibacillus close relat type strain paenibacillus solanacearum rrna gene sequenc similar valu paenibacillus speci dna dna hybrid ddh valu type strain p solanacearum reciproc respect averag nucleotid ident silico ddh valu type strain p solanacearum respect quinon system strain jj consist exclus menaquinon major compon mk minor amount mk detect well polar lipid profil consist major compon diphosphatidylglycerol phosphatidylethanolamin phosphatidylglycerol unidentifi aminolipid major fatti acid iso anteiso branch major compound anteiso c iso c physiolog biochem characterist allow phenotyp differenti strain jj close relat speci basi glucos l arabinos mannos assimil physiolog test thus jj repres novel speci genus paenibacillus name paenibacillus allorhizosphaera sp nov propos jj lmg ccm cip type strain | D056507;D010802;D058441;D012988 | T007;T078;T067;T070;T062 |
34,672,915 | telomer length urinari hydroxi deoxyguanosin essenti trace element concentr femal japanes univers student telomer length thought biomark biolog age studi examin whether telomer length associ urinari concentr hydroxi deoxyguanosin ohdg biomark oxid stress antioxid trace element femal japanes univers student age year quantifi ohdg selenium urin liquid chromatographi mass spectrometri induct coupl plasma mass spectrometri respect telomer length urinari concentr essenti trace element molybdenum cobalt chromium previous measur studi particip use studi use multipl linear regress analysi examin associ telomer length urinari ohdg essenti trace element concentr covari urinari cotinin concentr age bmi drink status geometr mean geometr standard deviat ohdg selenium gg creatinin respect telomer length associ urinari ohdg concentr negat associ urinari selenium concentr conclus telomer length associ urinari ohdg concentr young women studi longitudin studi conduct clarifi associ telomer shorten rate oxid stress level | D014131 | T121;T196;T123 |
34,672,914 | perspect review impact molecular mechan environment carcinogen human health cancer one lead caus death around world group diseas character abnorm uncontrol divis cell lead sever health condit fatal remain undiagnos till later stage cancer caus due mutat sudden alter effect certain extern agent agent caus sudden alter genet content individu known mutagen mutat lead perman chang genet constitu individu possibl lead cancer mutagen agent possess capac induc cancer human call carcinogen carcinogen may natur present environ generat anthropogen activ howev progress molecular techniqu genet andor epigenet mechan carcinogenesi wide rang carcinogen elucid present review aim discuss differ type environment carcinogen respect mechan respons induc cancer human | D002274;D009369 | T131;T191 |
34,672,913 | integr multi omic reveal common properti under stress granul p bodi format non membran bound compart p bodi pbs stress granul sgs play import role regul gene express follow environment stress systemat quantit determin protein mrna composit pbs sgs form nutrient stress find high molecular weight hmw complex exist prior glucos deplet propos may act seed condens protein form matur pbs sgs identifi enrich protein low complex rna bind domain well long structur mrnas poor translat follow nutrient stress mani protein mrnas share pbs sgs includ sever multival rna bind protein promot condens interact liquid liquid phase separ uncov numer common protein rna compon across pbs sgs support complex interact profil matur biolog condens interact network repres tuneabl respons stress highlight previous unrecogn condens heterogen studi therefor provid integr quantit understand dynam natur key biolog condens | D023281;D040901;D013312 | T121;T039;T046;T091;T032;T040 |
34,672,912 | eccentr gaze possibl caus zoom fatigu covid pandem led mark increas use videoconferenc social interact mani peopl report discomfort disaffect modal label zoom fatigu common videoconferenc hardwar setup necessit user look imag person videoconfer look direct camera appear make direct eye contact studi determin minimum threshold eccentr gaze videoconferenc setup subject perceiv make direct eye contact major untrain observ | D000086382;D058873 | T047;T067 |
34,672,911 | signific mild thrombocytopenia mainten hemodialysi patient retrospect cohort studi platelet activ hemodialysi hd circuit often caus thrombocytopenia howev clinic pathophysiolog signific rare explor herein investig predict valu thrombocytopenia cardiovascular event cve mainten hd patient attempt explor mechanist background consid recent knowledg platelet dynam conduct retrospect cohort studi hd patient composit primari endpoint predict cve ie myocardi infarct ischem stroke cardiovascular death baselin clinic data analyz explor multivari cox regress analysi show platelet decreas independ associ cve thrombocytopenia correl disus antiplatelet therapi apt macrocytosi find possibl associ platelet activ senesc hematopoiesi prognost signific thrombocytopenia promin patient undergo apt impli presenc apt resist platelet patient fulli explain result hypothes hd activ platelet induc biolog age hematopoiesi presum extramedullari lung activ platelet could deliv massiv amount inflammatori cytokin reactiv oxid speci result product qualit alter hyper reactiv platelet process could form vicious cycl induc cve associ thrombocytopenia investig focus dynam biolog age platelet hd patient warrant | D000740;D013921 | T047 |
34,672,908 | financi aid polici shortchang american healthcar issu medic school debt increas trend may reduc access medic school time histor recognit need greater open divers medic educ disadvantag candid underrepres medicin effect high educ relat debt medic school need greater consider evid implement staircas model employ len understand impact debt traine underrepres medicin healthcar system overal higher debt burden associ wors mental health outcom increas odd attrit medic school traine cite debt concern consid primari care career greater debt less like pursu remain academ career implic current financi aid system relianc high debt burden undermin goal improv represent underrepres candid primari care academ medicin altern model requir less debt could facilit creation divers workforc healthcar | D002321;D004501 | T065;T041 |
34,672,907 | discret time risk structur model cholera infect cameroon recent paper che et al use continu time ordinari differenti equat ode model risk structur studi cholera infect cameroon howev popul report cholera case cameroon censor discret time annual interv paper unlik introduc discret time risk structur cholera model spatial structur use discret time demograph equat fit annual popul cameroon furthermor use fit discret time model captur annual report cholera case studi impact vaccin treatment improv sanit number cholera infect discret time cholera model confirm result ode model howev discret time model predict decreas number cholera case shorter period cholera intervent compar ode model period intervent | D002771 | T047 |
34,672,905 | trim critic orchestr centrosom function loss function mutat e ubiquitin ligas trim result mulibrey nanism diseas character impair organ growth high propens develop differ tumor type addit increas copi number trim featur breast cancer neuroblastoma molecular role play trim loss gain function condit focus research last decad led notabl identif critic role trim centrosom biolog specif delet trim result format aberr centrosom protein assembl includ centrobin plk assembl act extra mtoc thus result defect chromosom segreg addit trim overexpress target centrosom protein cep degrad therebi prevent centrosom matur increas frequenc mitot error interest increas trim protein level sensit cell plk inhibitor centrinon review cover emerg role trim centrosom biolog discuss knowledg may lead new therapeut strategi target specif cancer cell | D050336;D044767 | T116;T047;T126 |
34,672,904 | evalu feasibl efficaci novel cbtismt treatment protocol cardiac rehab patient non random pilot trial cardiac patient chronic medic condit often suffer comorbid insomnia mood disord previous treatment protocol focus resolv symptom anxieti depress popul use stress manag train smt howev treatment neglect import sleep problem patient pilot trial sought address examin feasibl novel cbtismt treatment protocol | D007319 | T048;T047;T184 |
34,672,903 | alu rna role human diseas state alu rna implic poor prognosi sever human diseas state rna transcript product primat specif transpos element call alu element element extrem abund compris human genom cytoplasm copi alu rna per cell alu rna singl univers function role asid selfish self propag despit alu rna found oper divers set translat transcript mechan review focus current knowledg alu rna involv human diseas state known mechan action exampl alu rna transcrib varieti context intron matur mrna non code transcript discuss past present challeng studi alu rna futur direct alu rna basic clinic research also examin | D020087;D015415;D004198;D005786 | T045;T123;T114;T201;T080 |
34,672,902 | effect purif human chorion gonadotropin product high specif polyclon anti hcg compon radioimmunoassay kit studi aim purifi human chorion gonadotropin hcg urin pregnant women high biolog activ iumg puriti simpl captur hcg use deae sepharos ff polish use sephacryl hr hcg obtain character sds page dissoci alpha beta subunit use urea treatment method hcg subunit inject rabbit product high specif polyclon anti hcg antisera polyclon anti hcg local produc rabbit assess bind titer displac specif purifi hcg along local prepar polyclon anti hcg antisera use basic compon hous radioimmunoassay system quantit estim hcg human serum | D006063;D018997 | T116;T121;T125 |
34,672,901 | rat bite fever case report review rat bite fever rare diseas challeng differenti diagnosi zoonosi potenti lethal cours vulner popul children low socioeconom class common avail standard therapi penicillin case report review outlin common epidemiolog clinic factor improv clinic awar time respons therapeut action | D011906;D013288 | T007;T047 |
34,672,900 | emerg covid evolut endem pandem human race surviv sever outbreak pandem past impact long last recent pandem caus virus known coronavirus cov divers complex adapt virus signific impact human health anim product novel coronavirus emerg wuhan china sar cov quick spread throughout world human coronavirus hcov includ sever acut respiratori syndrom coronavirus sar cov novel coronavirus ncov also known sar cov led global epidem high morbid mortal human pathogen coronavirus sar cov sar cov bind target cell angiotensin convert enzym ace express epitheli cell lung intestin kidney blood vessel effort contain virus undergo throughout world given mani uncertainti regard pathogen transmiss virul thus ongo studi promot understand hcov help avoid orand minim impact anticip pandem futur | D000086382;D058873;D045473;D000086402;D045169 | T047;T005;T067 |
34,672,898 | tailor antiplatelet bridg therapi cangrelor move toward person medicin set patient indic receiv dual antiplatelet therapi undergo surgeri invas procedur risk periop cardiac ischem event particular stent thrombosi high surgeri prothrombot effect antiplatelet therapi withdrawn order avoid bleed complic cangrelor intraven py receptor antagonist test random trial bridg cardiac surgeri discontinu oral py receptor antagonist thus consensus document extend label use set non cardiac surgeri current despit implement standard bridg protocol cangrelor residu risk advers outcom main due bleed event still persist periop phaseaccord person manag driven platelet reactiv serial measur care assess ischem bleed risk potenti optim outcom cost compar standard bridg protocol base averag pharmacodynam data oral py inhibitorswhil specif indic bridg extens address aforement consensus statement aim present document propos tailor clinic decis make algorithm inspir principl person medicin deal complex clinic scenario | D010975;D058921 | T121 |
34,672,896 | prevent health care inform social media consum prefer dissemin prevent health care inform phci creat social econom valu enhanc communic health inform depend upon identif effect channel user prefer recogn consum find internet increas social media site facebook youtub import sourc phci research analyz questionnair respons us adult identifi social media site smss communic prefer sourc consum prefer obtain phci via social media | D054626;D061108 | T170 |
34,672,890 | understand clinician strategi discuss drive fit patient initi improv provid patient discuss safe drive object frequent overlook factor contribut traffic crash driver medic condit includ cognit physic impair compromis individu abil drive safe clinician critic posit often legal mandat identifi patient impair may affect drive abil counsel appropri next step howev prior studi reveal provid patient discuss drive occur relat infrequ clinician recommend patient could resum drive vari substanti chen et al drazkowski et al research aim document current driver fit assess practic among neurolog neurosurgeri clinician academ medic center overal purpos inform qualiti improv effort method cross section anonym survey distribut physician advanc practic provid work neurosurgeri neurolog depart larg pennsylvania base academ medic center survey question domain includ frequenc discuss drive comfort discuss drive patient criteria use assess patient fit drive driver rehabilit program referr practic pennsylvania depart transport penndot report result survey reveal although provid high level perceiv respons counsel patient drive minor regular discuss drive issu patient prior discharg clinic visit addit half provid report ever file report patient penndot despit pennsylvania mandatori driver report law likelihood penndot report found strong associ provid knowledg pennsylvania unsaf driver report law p conclus find highlight need enhanc standard care practic relat driver screen counsel report overal provid recogn import role advis patient safe drive desir standard protocol guid convers drive patient penndot report refer patient driver rehabilit servic | D000063;D001334 | T056;T037;T067 |
34,672,889 | develop concis injuri sever predict model pediatr patient involv motor vehicl collis transport sever injur pediatr patient trauma center shown decreas mortal decis support tool assist emerg medic servic em provid trauma triag would parsimoni possibl high accur object studi determin minimum set predictor requir accur predict sever injuri pediatr patient | D000063;D014947 | T037;T067 |
34,672,888 | diagnost periton aspir revisit diagnost accuraci detect intraabdomin hemorrhag use focus assess sonographi trauma fast combin comput tomographi ct becom mainstay diagnost workup patient suspect intraabdomin hemorrhag iah howev diagnost periton aspir dpa import adjunct hemodynam unstabl patient aim studi evalu util diagnost accuraci dpa detect iah | D061765 | T060 |
34,672,886 | complement femur model valid variabl focus approach short communic present approach object mean valid popul variabl potenti incorpor human bodi model accur way complement exist valid techniqu base individu experi simul comparison shall provid option assess qualiti larg number statist simul human bodi model regard biofidel behavior | D000063;D005269 | T023;T037;T067 |
34,672,885 | effect alcohol monitor treatment drive intox dwi offend literatur review synthesi advent continu passiv transderm alcohol monitor devic portabl breath test devic camera provid effici reliabl method control impair drive drive influenc dui offend object studi conduct comprehens literatur review synthesi strategi obstacl effect implement alcohol monitor compon treatment dui offend | D000435;D001334;D057237 | T098;T048;T056 |
34,672,884 | will drink drive investig indian scenario use extend prototyp willing model drive intox dwi signific threat traffic safeti worldwid littl known motiv factor behind willing drink drive especi low middl incom countri lmic india present studi appli extend version prototyp willing model pwm investig factor predict willing drink drive | D000063;D001334 | T056;T037;T067 |
34,672,881 | tetracyclin remov aqueous solut biochar deriv alga modifi mnmoo effect oper paramet isotherm kinet thermodynam studi aim present studi improv adsorpt tetracyclin tc onto biochar microalga modifi nanocomposit mnmoo mmbc synthes nanocomposit character scan electron microscopi sem brunauer emmett teller bet surfac area fourier transform infrar ftir spectroscopi investig morpholog surfac area pore function group mmbc respect effect various paramet includ initi ph tc concentr temperatur adsorpt perform tc adsorb evalu consid kinet isotherm thermodynam model adsorpt tc mmbc show good agreement pseudo second order kinet langmuir isotherm model result thermodynam studi show adsorpt process spontan endotherm reaction natur | D014874 | T131 |
34,672,880 | methodolog assess driver percept respons time unanticip cross centerlin event purpos studi present methodolog util naturalist drive data measur driver respons unanticip drive scenario cross centerlin event | D000063;D001334 | T056;T037;T067 |
34,672,879 | development trajectori drive attent adolesc preliminari find react character trajectori drive attent function age drive experi hypothes rate chang drive attent greater compar year old acquir drive experi vs non driver age drive experi interact effect drive experi stronger among compar year old | D000063;D001334 | T056;T037;T067 |
34,672,877 | novel electroencephalogram deriv measur disrupt delta wave activ sleep predict caus mortal risk rational convent marker sleep disturb base manual electroencephalographi score may adequ captur import featur fundament electroencephalographi relat sleep disturb object studi aim determin comprehens power spectral measur delta wave activ sleep stronger independ predictor mortal convent sleep qualiti disturb metric method power spectral analysi delta frequenc band spectral entropi base marker quantifi disrupt electroencephalographi delta power sleep perform examin potenti associ mortal risk sleep heart health studi cohort n adjust cox proport hazard model use determin associ disrupt delta wave activ baselin caus mortal approxim year follow period result disrupt delta electroencephalographi power sleep associ increas risk caus mortal compar fragment hazard ratio confid interv adjust total sleep time clinic lifestyl relat covari includ sleep apnea associ similar magnitud reduct total sleep time hour hour convent measur sleep qualiti includ wake sleep onset arous index predict caus mortal conclus delta wave activ disrupt sleep strong associ caus mortal risk independ tradit potenti confound futur investig potenti role delta sleep disrupt specif advers health consequ cardiometabol mental health safeti outcom consider potenti provid uniqu neurophysiolog insight | D012890;D012891 | T040;T033;T047 |
34,672,874 | sequenc variat etec cs operon affect transcript protein express enterotoxigen escherichia coli etec lead caus diarrheal diseas develop nation account signific diseas burden children age month also number one bacteri causat agent travel diarrhea etec infect host fecal oral rout util colon factor cf adher within small intestin cfs identifi consid major cfs vaccin target predict provid protect etec associ diseas coli surfac antigen cs major cf associ diseas caus etec isol analysi cs operon sequenc led identif two region variabl among clinic isol predict exert effect cs transcript protein express total recombin e coli strain engin encod cs operon wild type hybrid mutant configur western blot analysi rt qpcr provid evid support import intergen hairpin structur cs express result reveal signific cs sequenc select regard etec vaccin develop present novel inform regard cs sequenc variat wt etec strain | D000942;D054307;D004927;D029968 | T047;T129;T007;T116 |
34,672,872 | treatment trial young patient chronic obstruct pulmonari diseas pre chronic obstruct pulmonari diseas patient time move forward chronic obstruct pulmonari diseas copd end result seri dynam cumul gene environ interact lifetim evolv understand copd biolog provid novel opportun prevent earli diagnosi intervent advanc concept propos therapeut trial two major group subject young individu copd pre copd given lung grow year age begin age approxim year consid young patient copd patient age rang year pre copd relat individu age respiratori symptom without structur andor function abnorm absenc airflow limit may develop persist airflow limit time exclud current discuss infant adolesc uniqu physiolog context copd older adult given represent prior random control trial rcts highlight need rcts focus copd young patient pre copd reduc diseas progress provid innov approach identifi engag potenti studi subject detail approach rct design includ potenti outcom lung function patient report outcom exacerb lung imag mortal composit endpoint critic review studi design compon statist power analysi durat studi treatment format trial structur includ platform basket umbrella trial provid call action treatment rcts young adult copd pre copd age | D012107 | T170;T169;T062;T081;T096 |
34,672,870 | multidimension sexual well scale older adult valid evid polish sampl report result polish adapt multidimension sexual well scale mswbs older adult mswbs short self report scale assess five dimens individu sexual well frequenc caress sexual intimaci sexual complianc sexual satisfact sexual distress aim adapt examin util scale countri conserv view sexual older peopl help health care provid research better understand sexual need older peopl studi includ particip age found reliabl scale satisfactori cronbach alpha confirmatori factor analysi cfa show good fit data five factor model studi demonstr mswbs pl connect general life satisfact divers sexual activ confirm scale validitysupplement data articl avail onlin https doiorgx | D012725 | T032;T053;T055 |
34,672,869 | lesson unlearn conceptu review meta analysi relationship attent control scale object attent control attent control central mani model emot among common measur attent control attent control scale ac exert consider influenc term volum breadth research find use cognit experiment research continu increas recent year howev grow concern whether ac genuin index attent control present paper consid context develop ac review meta analys avail evid regard associ object measur attent control meta analyt result nine studi total n indic full scale ac signific associ behaviour measur attent control r p n ci find indic like miss studi lower correl suggest true associ may smaller limit evid share varianc subject object measur attent control contrast consider evid scale close correl disposit trait eg anxieti agreeabl could plausibl influenc respond thus balanc current find conclud littl compel evid respond ac reflect genuin attent control abil | D001007;D001288 | T048;T184;T041 |
34,672,864 | age stereotyp nutrit supplement use among middl age older women age women take relat high count medic nutrit supplement addit supplement roster increas likelihood experienc advers health outcom given public health implic isol effect chronolog age old age stereotyp drive number nutrit supplement taken middl age older women unit state use multipl model converg find middl age women older women high endors negat old age stereotyp take supplement age peer fail high endors negat old age stereotyp | D000375;D013240 | T040;T033;T041;T078 |
34,672,862 | racialethn differ tobacco use cessat servic among individu substanc use treatment studi explor racialethn dispar tobacco use access cessat servic among peopl substanc use disord sud collect data hispan n non hispan white n non hispan black n across californian residenti sud treatment program data analyz via regress model adjust demograph cigarett per day past quit attempt intent quit next day physic health status non hispan white smoke higher rate hispan non hispan black smoke cigarett per day sd hispan like non hispan white receiv referr cessat specialist adjust odd ratio aor ci tobacco cessat counsel aor ci non hispan black also like non hispan white receiv cessat counsel aor ci nrtpharmacotherapi aor ci despit decreas smoke preval sever rem access smoke cessat servic treatment suggest sud treatment could serv place address tobacco relat racial inequ | D016540;D019966 | T033;T048;T055 |
34,672,861 | femal sexual function women use larc method studi aim assess sexual function sf qualiti life qol among women use copper intrauterin devic cu iud levonorgestrel releas intrauterin system lng ius etonogestrel eng releas subderm implant | D011788 | T078 |
34,672,860 | fama promot prolifer bovin preadipocyt target hypoxia induc factor signal pathway famili sequenc similar member fama gene discov recent year relat metabol studi function fama precursor adipocyt prolifer qinchuan cattl investig use fluoresc quantit polymeras chain reaction pcr western blot ethynyl deoxyuridin stain test fama promot precursor adipocyt prolifer determin pathway fama involv transcriptom sequenc fluoresc quantit pcr western blot test use identifi hypoxia induc factor hif signal pathway final cobalt chlorid chemic mimic hypoxia use treat precursor adipocyt mrna protein level fama signific increas hypoxia thus fama promot bovin precursor adipocyt prolifer inhibit hif signal pathway wherea chemic induc hypoxia negat regul fama express regul cell prolifer | D051793;D015398 | T043;T044;T116;T123 |
34,672,859 | intellig type diabet risk predict administr claim data type diabet chronic cost diseas serious global popul health problem yet diseas well manag prevent earli warn studi aim appli supervis machin learn algorithm develop predict model type diabet use administr claim data follow guidelin elixhaus comorbid index variabl consid five supervis machin learn algorithm use develop type diabet predict model princip compon analysi appli rank variabl import predict model random forest rf show highest accuraci among algorithm close follow k nearest neighbor analysi reveal rf high perform algorithm irrespect data imbal reveal princip compon analysi patient age import predictor type diabet follow comorbid condit ie solid tumor without metastasi studi find rf best perform classifi consist promis tree base algorithm public data work thus outcom guid design autom surveil patient risk form diabet administr claim inform use health regul insur | D003924;D000069550 | T047;T066 |
34,672,857 | clinic present type type pyrethroid poison human unclear clinic present poison type type pyrethroid compound differ studi undertaken detail clinic profil outcom patient present pyrethroid poison quantifi serum pyrethroid level | D007306;D011722 | T131;T109 |
34,672,856 | impact electron health record function pattern depress treatment primari care mani individu depress link treatment primari care provid electron health record ehr common medicin impact depress treatment mix ehr divers differ may attribut differ function studi examin relationship ehr function pattern depress treatment primari care | D003863;D057286 | T048;T170;T184;T073 |
34,672,855 | fraction nm picosecond laser skin photoag vivo evalu treatment effect reflect confoc microscopi studi show role picosecond laser pls treatment skin photoag sign howev studi explor microscop effect psl photoag aim studi preliminarili identifi clinic variat induc nm nd yag psl dcollet area appli treatment protocol treat facial photoag estim clinic microscop outcom total consecut patient cutan photoag enrol patient treat time month interv fraction nm nd yag psl preliminari phase psl treatment perform dcollet establish efficaci safeti treatment protocol appli face clinic reflect confoc microscopi rcm analyz compar baselin pictur month treatment one face reduct dyschromia wrinkl observ furthermor under rcm variat reveal differ skin level result show clinic microscop effect safeti nm nd yag psl treatment skin photoag sign | D053844;D015595 | T033;T074;T042;T073 |
34,672,853 | drive older adult use mobil registr app taiwan investig use extend utaut model studi aim provid integr model examin determin older adult intent use mobil registr applic app base utaut role age factor includ perceiv physic condit technolog anxieti inertia self actual need propos model test pls partial least squar data collect older adult result indic three variabl deriv utaut name perform expect social influenc facilit condit influenc mobil registr app usag intent addit age factor inertia self actual need signific impact older adult usag intent result demonstr smart phone usag experi moder effect relationship usag intent three anteced perform expect effort expect facilit condit social influenc find provid valuabl theoret contribut research practic implic hospit develop mobil registr app taiwan | D063731 | T170 |
34,672,852 | resid subject mental workload computer prescript entri examin resid subject mental workload enter prescript computer physician order entri cpoe system twenti two resid complet six prescrib task two factor manipul numer input method level urgenc data demograph characterist familiar cpoe pretest perform collect subject mental workload measur nation aeronaut space administr task load index nasa tlx tempor demand mean contribut resid workload cpoe task follow perform mean signific associ found workload demograph characterist cpoe familiar pretest cpoe perform p repeat measur anova yield main effect numer input method f p level urgenc f p interact input method urgenc f p resid major sourc workload cpoe prescript tempor demand perform prescript enter row number exhibit highest workload workload increas higher level urgenc necessari emphas negat impact subject workload especi prescript task urgent situat research focus medic staff workload encourag ensur patient safeti | D013647;D016526 | T057;T061;T081 |
34,672,851 | telemedicin solut patient mental disord delphi studi review mobil applic virtual store mental disord critic public health challeng sinc profound affect peopl lifestyl mental healthcar treatment aim promot higher qualiti life patient procedur includ intervent prolong mental ill support telemedicin technolog paper present comprehens analysi mobil applic select address critic need peopl mental problem need includ area patient life basic activ behavior chang daili life task work two main object identifi critic need patient mental disord identifi analyz app meet identifi critic need delphi methodolog survey carri group thirteen volunt includ nurs assist psychiatrist work zamora valladolid spain survey recommend differ need patient mental disord address object googl play appl store assess select relev mobil applic recommend delphi studi address essenti need patient accord object result delphi survey show differ need patient mental disord studi analyz mobil applic address essenti need recommend delphi studi select mobil applic repres applic feedback inform applic independ applic one hand applic feedback request address recommend need hand inform applic address need final independ applic abl respond recommend need mobil health applic present effect technolog support need patient mental disord howev studi suggest critic limit mobil applic mental health sinc major applic requir user activ therefor futur research initi design develop mobil app peopl mental disord focus independ applic | D001523;D063731;D017216 | T058;T048;T170 |
34,672,849 | outcom surviv open heart surgeri adult congenit heart diseas singl center experi introduct congenit heart diseas chd common type birth defect today adult congenit heart diseas achd popul constant grow becom older patient requir cardiac surgeri object studi review surgic outcom open heart procedur perform achd patient last year sahlgrenska univers hospit suh retrospect descript cohort studi method retrospect data collect perform patient underw total surgic procedur cardiothorac depart suh primari outcom earli h conclus studi present satisfactori earli midterm surviv surviv frequenc major postop complic well line studi present patient undergo resternotomi increas risk mortal postop complic | D006348;D006330 | T019;T061 |
34,672,848 | nutrit obstetr determin iron defici anemia among pregnant women attend antenat care servic public health hospit abidjan cte divoir cross section studi poor diversifi micronutri defici dietari intak pregnanc remain one major caus nutrit anemia develop countri howev data diet relat anemia pregnant women cte divoir scarc object studi determin preval iron defici anemia associ factor pregnant women abidjan cross section studi conduct among pregnant women attend antenat care servic public health hospit abidjan sociodemograph obstetr dietari data collect blood sampl taken venipunctur analyz hemoglobin iron biomark data subject descript statist multivari logist regress pregnant women test anem iron defici iron defici anemia respect base aor second third trimest pregnanc v respect multipar skip meal inadequ energi protein vitamin c intak low dietari divers independ signific determin iron defici anemia high preval anemia among pregnant women abidjan reveal real public health problem iron defici anemia due multipar gestat age inadequ intak low dietari divers skip meal | D000740;D000090463 | T047 |
34,672,847 | safeti effect mirabegron parkinson diseas patient overact bladder random control trial assess safeti effect mirabegron patient pd complain overact bladder oab | D010300;D053201;D064804 | T047;T121 |
34,672,844 | leptospir meningoenceph raccoon dog neuroleptospirosi rare diseas caus pathogen leptospira interrogan human howev fulli studi anim young wild raccoon dog found convuls recumb posit die next day histolog examin reveal nonsuppur meningoenceph cerebrum cerebellum midbrain medulla oblongata lesion consist mix infiltr iba posit macrophag cd posit cell small number cd posit b cell myeloperoxidas posit neutrophil frontal cortex perivascular cuff adjac microgli nodul distribut diffus especi molecular layer glial nodul compris iba myeloperoxidas posit activ microglia immunohistochemistri reveal leptospir mononuclear cell perivascular cuff glial nodul neuroleptospirosi accompani leptospira relat nonsuppur interstiti nephriti pulmonari edema hemorrhag coronari periarter well toxocara tanuki small intestin nonspecif foreign bodi granuloma lung stomach | D007919;D008590 | T007;T047 |
34,672,842 | matern glucos variabl pregnanc birthweight percentil women pre gestat diabet pre gestat diabet mellitus pgdm major risk factor fetal overgrowth interest even relat well control pgdm women determin averag glucos indic hbac increas rate lga larg gestat age glucos variabl gv emerg import independ risk factor sever diabet complic aim studi determin relationship matern gv indic neonat birth percentil | D001724;D001786 | T032;T109 |
34,672,840 | non complianc carri day evalu effect employ program sever mental ill mental diseas increas worldwid peopl suffer show lower employ rate lower earn various approach tri increas employ rate peopl mental diseas us empir studi show individu placement support ip rapid transit job market extern assist effect increas employ rate mental ill europ lack evid studi assess impact ip like program undertaken itali employ rate peopl sever mental ill analysi base rct test whether offer peopl sever mental ill support job coach increas chanc employ moreov use batteri test one made avail rct show larg non complianc protocol show rct ignor motiv estim impact carri traineeship experiment period employ use non experiment method studi find avail coach boost patient chanc find traineeship experiment period moreov undertak traineeship almost doubl likelihood work one year later jel code j j j | D001523;D028642 | T048;T101 |
34,672,839 | oral health status oral health relat qualiti life first nation meti children assess oral health status oral health relat qualiti life ohrqol young first nation meti children | D003731;D009909 | T033;T047 |
34,672,837 | covid convers within blackbrown minor communiti stakehold psychoeduc approach use zoomfacebook live communiti color disproportion affect covid urgent need dissemin time accur inform communiti member articl describ stakehold approach implement evalu lesson learn covid convers program develop deliv virtual research academ northwel health goal program address mental physic psychosoci need communiti member program use zoomfacebook live deliv interact discuss topic rang health educ covid mental health resourc unmet social need interprofession cross sector collabor highlight import public health intervent aim reduc spread covid easi onlin access cultur relev communiti educ outreach | D000086382;D061108 | T047;T170;T067 |
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