PMID int64 27.8M 36.2M | Title/Abstract stringlengths 7 10.7k | MeshTerms stringlengths 7 104 | SemanticTypes stringlengths 4 84 |
|---|---|---|---|
34,669,231 | marin freshwat regim chang impact communiti migratori pacif salmonid declin marin freshwat ecosystem increas risk larg cascad chang multipl human activ term regim shift impact popul product resili ecosystem structur pacif salmon exhibit persist larg fluctuat popul dynam driven combin intrins eg densiti depend extrins factor eg ecosystem chang speci interact recent year mani pacif salmon declin due regim shift clear understand process drive chang remain elus unpack role densiti depend ecosystem trend stochast product regim communiti five anadrom pacif salmonid steelhead coho salmon pink salmon dolli varden coastal cutthroat trout across rich year time seri use bayesian multivari state space model examin whether product shift similar occur across communiti explor marin freshwat chang associ shift overal identifi three product regim earli regim compensatori regim declin regim sinc larg declin observ steelhead dolli varden cutthroat trout intermedi declin coho chang pink salmon regim chang associ multipl cumul effect across salmon life cycl exampl increas seal densiti ocean competit associ lower adult marin surviv steelhead watersh log also intensifi past year associ els equal declin freshwat product steelhead cutthroat coho steelhead marin freshwat dynam play approxim equal role explain trend total product collect chang environ limit juvenil product lower futur adult return result reveal chang freshwat marin environ joint shape popul dynam among ecolog communiti like pacif salmon cascad consequ resili | D017753;D017686 | T070;T013;T082 |
34,669,230 | translat research framework nurs practition studi aim explor propos translat research continuum nurs practition | D009722;D057170 | T097;T062 |
34,669,228 | window opportun ocean warm shape temperatur sensit epigenet reprogram gene express across gametogenesi embryogenesi marin stickleback rapid climat chang place mani marin speci risk local extinct recent studi show epigenet mechan eg dna methyl histon modif facilit within transgener plastic cope chang environ howev epigenet reprogram erasur establish epigenet mark gamet earli embryo develop may hinder transgener epigenet inherit knowledg reprogram stem mammal model organ wherea preval extent reprogram among non model speci wild popul rare investig moreov whether reprogram dynam sensit chang environment condit well known repres key knowledg gap pursuit identifi mechan under link parent exposur chang climat pattern environment adapt offspr phenotyp investig epigenet reprogram dna methylationhydroxymethyl gene express across gametogenesi embryogenesi marin stickleback gasterosteus aculeatus three ocean warm scenario ambient c found parent acclim ocean warm led dynam temperatur sensit reprogram throughout offspr develop global methylationhydroxymethyl express gene involv epigenet modif strong differenti affect increas warm scenario compar transcriptom profil gonad matur gamet earli embryon stage show sex specif accumul temperatur sensit sever epigenet actor dna methyltransferas induct primarili matern inherit suggest matern control remethyl wherea induct sever histon modifi enzym shape parent import massiv temperatur specif chang epigenet landscap occur blastula critic stage success embryo develop could thus translat substanti consequ offspr phenotyp resili warm environ summari studi identifi key stage gamet embryo develop temperatur sensit reprogram epigenet gene regul reflect potenti window opportun adapt epigenet respons futur climat chang | D023701 | T013 |
34,669,227 | great recess weight portugues children structur equat model approach consid eat pattern evid great recess associ childhood obes need particular world face new sever econom downturn caus covid pandem studi explor direct associ econom crisi eat pattern bodi mass index bmi among children independ socioeconom status ses indirect associ crisi children bmi use eat pattern mediat | D000086382;D063766 | T033;T047;T067 |
34,669,226 | tripl conjoin scapular latissimus dorsi groin flap reconstruct long lower extrem deglov injuri case report sinc introduct angiosom concept mani attempt made push dimension limit free tissu transfer initi limit boundari random vascular adjac angiosom wider flap transfer combin contigu sourc vessel combin flap either chimer conjoin repres nowaday largest reconstruct option human bodi first report tripl conjoin free flap two vascular anastomos abl cover anterior surfac entir lower limb repres longest flap ever report histori year old woman sustain car accid pedestrian present massiv circumferenti deglov injuri right lower limb femor displac shaft fractur gustilo type iiib tibial fractur diagnos emerg ct scan myocutan latissimus dorsi flap plan conjoin scapular flap obtain thick larg cover knee groin flap cover foot descend branch later circumflex femor arteri anterior tibial arteri dorsum foot select recipi vessel donor site close primarili flap surviv immedi late complic report follow month tripl conjoin flap consid safe use reconstruct tool sever deglov injuri lower limb allow coverag larg surfac lesion singl oper without increas donor site morbid | D000069836;D058752;D016462;D019651;D017695;D064171 | T061;T023;T024;T037 |
34,669,223 | assess extinct risk insular understudi marin speci hydrotherm vent rare deep sea oas hous faunal assemblag similar densiti life coral reef approxim hotspot known worldwid one third footbal field size advanc develop deep sea mine industri urgent need protect uniqu insular ecosystem specialist endem fauna appli iucn intern union conserv natur red list criteria assess extinct risk vent endem mollusc vari exposur potenti deep sea mine assess speci three key area differ regulatori framework indian west pacif southern ocean three vent mollusc speci also examin case studi differ threat context protect potenti mine explor interact local regulatori framework iucn red list categori assign found assess robust even uncertainti total rang individu speci allow assess speci recent name describ vent endem speci regulatori chang area base manag greater impact iucn red list assess outcom incorpor addit data speci distribut approach reveal use iucn red list criteria vent endem speci criteria b approach combin regulatori framework distribut potenti rapid gaug assess outcom speci insular system worldwid | D056727;D053476 | T070;T098 |
34,669,222 | valsartan nano filament alter mitochondri energet promot faster heal diabet rat wound chronic wound common debilit condit associ age popul impact million patient unit state previous demonstr efficaci daili topic valsartan treat wound diabet mous pig model despit promis result remain need develop extend releas formul would reduc patient burden decreas frequenc daili applic use nanotechnolog self assembl valsartan amphiphil filament structur val filament would serv scaffold wound bed allow steadi localis tunabl releas valsartan amphiphil day two topic treatment peptid base hydrogel full thick wound zucker diabet fatti rat result faster rate wound closur day val filament treat wound complet close compar one wound close placebo group mechanist observ enrich protein involv cell adhes energet pathway downregul tgf signal pathway mediat psmad psmad smad increas mitochondri metabol pathway intermedi studi demonstr success synthesi sustain releas valsartan filament hydrogel impact mitochondri energet efficaci treat diabet wound | D003920;D014945 | T040;T047 |
34,669,221 | phenotyp plastic drive phenolog chang mediterranean blue tit popul earlier phenolog induc climat chang passerin breed time observ mani natur popul understand natur chang key predict respons wild popul climat chang genet chang rare investig lay date though shown herit direct select suggest trait could evolv corsican blue tit popul bird lay date signific advanc year determin whether respons plastic evolutionari origin compar predict breeder robertson price sts equat observ genet chang compar result obtain two fit proxi fledgl recruit success use model account zero inflat trait appear herit direct select breeder equat predict genet chang could drive signific part phenolog chang observ howev found fit proxi lay date genet correl sts therefor predict evolut breed time predict correct absenc trend breed valu result also emphas investig select plastic trait fluctuat select part fit trait phenotyp covari due within individu covari case repeat measur split within individu covari shift perspect actual intens select multipl select episod shed light potenti trait evolv | D012641;D020308 | T070;T045;T012 |
34,669,220 | high electr conduct flexibl ionogel drop cast ionic liquidpedot pss composit liquid onto hydrogel network ionogel extens studi ideal flexibl stretchabl materi virtu uniqu properti ionic liquid non volatil non flammabl neglig vapor pressur howev general low ionic conduct current ionogel limit applic market high conduct flexibl stretchabl electr devic fabric high electr conduct ionogel report combin composit liquid consist ethyl methylimidazolium dicyanamid emim dca poli ethylenedioxythiophen poli styrenesulfon pedot pss flexibl negat charg poli acrylamido methyl propanesulfon acid pamp hydrogel generat composit film exhibit high electr conduct cm maximum tensil strain fractur stress kpa addit demonstr composit film maintain conduct high level differ mechan deform also use flexibl sensor wide temperatur rang believ design composit film would expand applic flexibl conduct materi high conduct robust mechan flexibl requir | D052578 | T120;T103 |
34,669,218 | machin learn model mitral valv replac compar analysi societi thorac surgeon risk score current societi thorac surgeon sts risk model predict outcom mitral valv surgeri mvs assum linear cumul impact variabl evalu postop mvs outcom design mortal morbid risk calcul supplement sts risk score | D019918;D066231 | T097;T061 |
34,669,217 | minim invas aortic valv repair use geometr ring annuloplasti aortic valv repair avr aortic insuffici ai expand minim invas mi approach increas appli cardiac surgic techniqu difficult small incis report analyz medium term outcom miavr facilit geometr ring annuloplasti | D001022;D058385;D006350;D019918 | T074;T047;T061 |
34,669,216 | cyclic perfluoropolyeth distinct film formabl thermostabil upon recycl cyclic linear topolog transform perfluoropolyeth pfpe industri import fluoropolym great industri import due flexibl noncombust chemic robust properti howev explor applic chemic modifi homogen pfpes hamper immisc nonfluorin contain molecul synthesi report cyclic pfpe hexaarylbiimidazol habi chain linear pfpe triphenylimidazol lophin end group phase separ end group main chain took place linear pfpe habi main chain cyclic pfpe miscibl form transpar glass film design cyclic pfpe also enabl cyclic linear topolog transform base convers habi lophin upon mild heat glass film state sequenti linear cyclic cyclic linear topolog transform enabl fabric thermostabil transpar film deriv pfpe | D004987;D005466 | T121;T109 |
34,669,215 | anteroposterior shear stiff upper thorac spine quasi static dynam load rate vitro biomechan studi evalu biomechan properti upper thorac spine anterior posterior shear load various displac rate data broaden understand thorac spine biomechan inform effort model spine spinal cord injuri seven thorac function spinal unit load non destruct pure shear forc n start neutral postur test run posterior anterior direct displac rate mms three dimension motion specimen record hz individu averag load displac curv generat specimen stiff calcul due nonlinear respons specimen stiff defin separ lower half upper half specimen rang motion specimen signific stiffer anterior direct posterior direct across rate low displac anterior stiff averag nmm higher low displac posterior stiff nmm high displac anterior stiff averag nmm stiffer high displac posterior stiff nmm shear displac rate small effect load respons mms rate caus mild stiffer respons low displac anterior direct overal load displac respons exhibit pseudo quadrat behavior mms becam linear mms shear stiff upper thorac spine greatest anterior load direct greater posterior like due facet interact effect shear displac rate low | D011187;D013131 | T033;T023 |
34,669,214 | cholecystectomi cat describ clinic present treatment long term outcom follow cholecystectomi cat | D002371;D017081;D001651 | T047;T061 |
34,669,213 | neurocognit declin cardiac surgeri distract rather destruct neurocognit declin undesir event observ patient cardiac surgeri relat use cardiopulmonari bypass cpb minor embol hyperinflammatori mechan thought respons issu journal cardiac surgeri neurocognit declin observ patient cardiac surgeri cpb repeat neuropsycholog status test use score day surgeri lower mechanist investig glycem control transcriptom cytokin analys fail provid explan frequenc observ worrisom | D006348;D003072;D062645 | T048;T061 |
34,669,211 | emerg surgic treatment total anomal pulmonari venous connect studi explor strategi effect emerg surgic treatment total anomal pulmonari venous connect tapvc | D011667;D012587 | T047;T023;T019 |
34,669,206 | progress patholog arena gynecolog cancer review cover signific new develop patholog classif gynecolog tumor mani includ updat world health organ classif femal genit tract tumour publish topic includ compel evid larg major extrauterin high grade serous carcinoma aris fallopian tube cancer genom atlas tcga classif endometri carcinoma discoveri call synchron endometri ovarian endometrioid carcinoma repres metastasi endometrium ovari divis cervic vagin vulval carcinoma clinic meaning hpv associ hpv independ type newli describ tumor type cover includ endometri ovarian mesonephr like adenocarcinoma uterin sarcoma type associ specif molecular abnorm gastric gastrointestin type adenocarcinoma endometrium vagina import molecular event ovarian sex cord stromal tumor also discuss | D000230;D018269;D016889;D010051;D014594 | T191 |
34,669,205 | obes gynecolog cancer toxic relationship despit evid support relev obes obes associ disord develop manag prognosi various cancer obes rate continu increas worldwid grow evid support involv obes develop gynecolog malign articl explor molecular basi govern alter hallmark cancer develop obes relat gynecolog malign encompass cervic endometri ovarian cancer highlight specif exampl develop manag prognosi affect cancer incorpor current knowledg complementari approach includ lifestyl intervent improv patient outcom highlight new technolog help us better understand biolog under neglect pandem | D016889;D005833;D010051;D002583 | T191 |
34,669,204 | cancer vulva updat vulvar cancer uncommon gynecolog malign primarili affect postmenopaus women specif screen effect strategi reduc vulvar cancer incid opportun treatment predispos preneoplast lesion associ develop vulvar cancer may asymptomat women present vulvar pruritus pain notic lump ulcer therefor suspici vulvar lesion biopsi exclud invas establish common subtyp squamous cell carcinoma treatment vulvar cancer depend primarili histolog surgic stage treatment predomin surgic particular squamous cell carcinoma although concurr chemoradi effect altern particular advanc tumor manag individu carri multidisciplinari team cancer center experienc treatment tumor | D002294;D014846 | T191 |
34,669,203 | cancer cervix uteri updat sinc public figo cancer report giant stride made global effort reduc burden cervic cancer world health organ roll global strategi cervic cancer elimin aim implement countri includ low middl incom countri hpv vaccin includ nation program screen seen major advanc wider implement hpv test intervent take year show impact meanwhil half million new case ad year figo revis stage cervic cancer wide implement retrospect analys data base new stage publish minim invas surgeri shown disadvantag women cervic cancer chapter discuss manag cervic cancer base stage diseas includ attent palliat qualiti life issu | D030361;D002583 | T191;T047 |
34,669,202 | reach women greatest need two model initi scale gynecolog oncolog fellowship train low resourc set women low middl incom countri lmic signific like develop die invas cervic cancer rate gynecolog malign compar face women high incom countri despit increas need specialist physician lmic avail treat women gynecolog cancer train specialist low resourc set face multipl challeng includ ensur protect time clinic demand access best practic guidelin train tailor specif challeng face traine environ isol fulli train profession secur support servic addit train specialist lmic high resourc set cost return traine countri guarante describ two approach gynecolog oncolog train lmic intern gynecolog cancer societi igc develop global curriculum mentorship train program global curriculum support gynecolog oncolog fellowship region world current formal train gynecolog oncolog india hand leader world class gynecolog oncolog center must find way meet train need vast dispar countri | D005833;D002583 | T191 |
34,669,201 | worldwid initi elimin cervic cancer women diagnos cervic cancer women die worldwid without comprehens control rate cervic cancer incid mortal expect worsen world health organ adopt global strategi elimin cervic cancer threshold four case per women within st centuri use tripl pillar intervent strategi compris girl fulli vaccin age year women screen age year year women precanc treat women invas cancer manag countri high cervic cancer incid tremend effort need overcom challeng articl discuss effort place acceler achiev ambiti goal | D030361;D002583 | T191;T047 |
34,669,200 | covid impact gynecolog cancer care covid pandem result signific reconfigur gynecolog cancer servic care pathway across globe transform work practic servic adapt protect vulner patient infect whilst provid care despit reduc resourcescapac staf intern gynecolog cancer communiti introduc modifi clinic care guidelin remot work reduc hospit visit routin covid test use covid free surgic areashub enabl ongo safe deliveri complex cancer care prioriti level cancer treatment establish guid decis make multidisciplinari tumor board million cancer surgeri delay cancel first peak mani patient report signific anxietyconcern cancer progress covid infect although covid trial priorit recruit cancer trialsresearch activ signific reduc impact result protocol deviat outcom remain establish recoveri healthcar servic must maintain capac flexibl manag futur surg infect address larg backlog patient alter delay treatment along salvag screen prevent servic train needsment well traine need address staff burnout prevent futur research need fulli evalu impact covid long term patient outcom | D000086382;D005833 | T191;T047;T067 |
34,669,199 | cancer ovari fallopian tube peritoneum updat figo committe gynecolog oncolog revis stage ovarian cancer incorpor ovarian fallopian tube periton cancer system malign high grade serous carcinoma hgsc stage ic divid three categori ic surgic spill ic capsul ruptur surgeri tumor ovarian fallopian tube surfac ic malign cell ascit periton wash updat stage includ revis stage iiic base spread retroperiton lymph node alon without intraperiton dissemin categori subdivid iiia metastasi mm greatest dimens iiia ii metastasi mm greatest dimens stage iiia microscop extrapelv periton involv without posit retroperiton lymph node metastasi review summar genet surgic manag chemotherapi target therapi epitheli cancer treatment ovarian germ cell stromal malign | D005185;D010051 | T191 |
34,669,198 | cancer vagina updat diagnosi primari vagin cancer rare vagin tumor metastat anoth primari site although cancer vagina common postmenopaus women increas young women diagnos primari vagin cancer report especi countri high hiv preval associ persist high risk hpv infect emphasi primari prevent prophylact hpv vaccin suspicion primari vagin cancer confirm histolog biopsi stage done clinic cervic cancer howev role imag assist stage often difficult assess treatment individu depend stage well histolog subtyp prudent refer case center excel experi deal rare gynecolog cancer | D030361;D002583;D014625 | T191;T047 |
34,669,197 | diagnosi manag gestat trophoblast diseas updat gestat trophoblast diseas gtd aris abnorm placenta compos spectrum premalign malign disord chang epidemiolog gtd note various countri addit histolog molecular genet studi help diagnost pathway earlier detect molar pregnanc ultrasound result chang clinic present decreas morbid uterin evacu follow human chorion gonadotropin hcg essenti earli diagnosi gestat trophoblast neoplasia gtn durat hcg monitor vari depend histolog type regress rate low risk gtn figo stage iii score treat singl agent chemotherapi may requir addit agent although score associ drug resist overal surviv approach high risk gtn figo stage ii iii score stage iv treat multiag chemotherapi without adjuv surgeri excis resist foci diseas radiotherapi brain metastas achiev surviv rate approxim gentl induct chemotherapi help reduc earli death patient extens tumor burden late mortal still occur recurr treatment resist tumor | D031901;D006828;D014594 | T191;T047 |
34,669,196 | cancer corpus uteri updat endometri cancer common gynecolog malign high middl incom countri although overal prognosi relat good high grade endometri cancer tendenc recur recurr need prevent sinc prognosi recurr endometri cancer dismal treatment tailor tumor biolog optim strategi balanc treatment efficaci toxic sinc cancer genom atlas defin four molecular subgroup endometri cancer molecular factor increas use defin prognosi treatment standard treatment consist hysterectomi bilater salpingo oophorectomi lymphadenectomi increas sentinel node biopsi enabl identif lymph node posit patient need adjuv treatment includ radiotherapi chemotherapi adjuv therapi use stage ii patient high risk factor stage iii patient chemotherapi especi use non endometrioid cancer copi number high molecular group character tp mutat advanc diseas combin surgeri residu diseas chemotherapi without radiotherapi result best outcom surgeri recurr diseas advoc patient good perform status relat long diseas free interv | D016889;D009364 | T191 |
34,669,195 | import public privat partnership nutrit support research aspen posit paper parenter enter nutrit support key compon care various medic physiolog condit infant children adult nutrit support practic advanc time driven goal safe suffici deliveri need nutrient improv patient outcom advanc continu depend research develop studi studi address aspect enter parenter nutrit support formul deliveri devic health outcom cost effect relat metabol studi support public fund govern privat fund foundat nutrit support industri build public trust nutrit support research find import underscor ethic research conduct report result studi includ industri sponsor american societi parenter enter nutrit aspen board director establish task forc ensur integr nutrit support research done collabor partnership public govern individu privat group foundat academia industri aspen posit paper task forc present principl ethic research guid administr research funder task forc identifi way curtail bias minim actual perceiv conflict interest relat fund sourc research conduct notabl paper includ posit statement describ task forc guidanc public privat partnership research fund paper approv aspen board director | D010288;D055818 | T092;T061;T064 |
34,669,194 | human factor minework fatigu overview preval mitig next though mine remain vital shiftwork industri us commerc problem continu preval minework fatigu mitig persist public report fatigu mine appear rich divers yet variabl remot much like industri | D000067572 | T097 |
34,669,193 | phylogeni classif charact evolut tribe citharexylea verbenacea famili neotrop origin primarili neotrop distribut verbenacea good understudi system understand neotrop evolut tribe citharexylea compris three genera baillonia citharexylum one largest genera verbenacea rehdera molecular phylogenet approach taken resolv intergener relationship citharexylea infragener relationship citharexylum phylogeni use elucid charact evolut widespread morpholog divers neotrop genus | D029648 | T002 |
34,669,192 | strength base cultur respons famili intervent improv latino kindergarten vocabulari approach learn food routin ecocultur asset latino famili cluster random trial children age month girl school investig impact week famili program design capit food routin improv latino kindergarten outcom unit state moder larg impact child vocabulari especi food relat end treatment month follow suggest evid moder impact approach learn atl includ atl math execut function month follow statist signific impact children math literaci skill strength base cultur respons famili intervent integr latino famili life improv skill need succeed school | D012574;D014825 | T092;T170;T073 |
34,669,191 | hazard function effect promot self control variabl interv time base intervent rat present experi investig properti time base intervent use increas self control rat receiv impuls choic assess intervent consist differ distribut delay reinforc experi rat receiv intervent increas hazard function delay even distribut decreas hazard function delay most short constant hazard function delay exponenti distribut surpris rat receiv decreas hazard function made self control choic respons rate intervent trial show rat anticip reinforc base shape distribut receiv experi rat receiv intervent decreas hazard function steep slope shallow slope time base intervent increas self control produc similar respons rate pattern indic slope decreas hazard function may play strong role intervent efficaci research align previous literatur show time base intervent improv self control exposur short delay produc biggest improv ultim exposur short delay may increas subject valu larger later choic occasion long delay may promot abil wait may import implic translat applic | D002755;D000068356 | T055 |
34,669,189 | evalu aortic biomechan patient aortic diseas via imag review bridg heart arteri aorta play import role cardiovascular system morbid mortal aortic diseas extrem high serious threat human life biomechan abnorm aorta import factor seri patholog chang aortic wall present mani imag method evalu biomechan aorta benefit earli diagnosi treatment aortic diseas review describ applic various imag method paramet aortic diseas | D001011;D001018 | T047;T023 |
34,669,188 | crucial role mitochondria support c photosynthesi c photosynthesi involv seri biochem anatom trait signific improv plant product condit reduc effici c photosynthesi explor evolut three classic biochem type c photosynthesi nadp nad pck type affect function properti mitochondria mitochondria c nad pck type play direct role decarboxyl metabolit c photosynthesi mitochondria c pck type also provid atp c metabol although role atp provis seen nad type involv increas mitochondri abundances associ enzymat capac led chang mitochondri locat ultrastructur alter role mitochondria cellular carbon metabol nad pck type contrast chang mitochondri properti absent c nadp type c leav mitochondria play direct role photosynthesi eco physiolog perspect rate leaf respir dark vari consider among c speci differ systemat among three c type review outlin mitochondri research key area central engin c pathway c plant understand variat rate c dark respir | D008291;D010788 | T044;T116;T039;T070;T126 |
34,669,187 | manag pre peri post menopaus abnorm uterin bleed perform endometri sampl abnorm uterin bleed aub defin abnorm volum durat frequenc menstrual period common symptom women age premenopaus perimenopaus postmenopaus acronym palm coein introduc intern feder gynecolog obstetr figo facilit evalu differenti diagnosi aub most premenopaus women aub endometri evalu includ ultrasound hysteroscop imag tissu sampl subtl patholog propos patient high risk endometri cancer patient low risk present aub present poor correspond medic treatment mani new diagnost modal avail clinician order help assess women present abnorm menstrual pattern present studi review optim manag women present aub take consider actual need invas manag women requir diagnos without histolog verif import endometri tissu sampl women present aub well best time clinician conduct biopsi two axon analyz accord latest worldwid guidelin major public subject | D014591;D014592 | T047;T046 |
34,669,186 | antepartum stillbirth rate covid pandem austria popul base studi coronavirus diseas covid pandem caus sever acut respiratori syndrom coronavirus dramat effect pregnant popul worldwid increas risk advers perinat outcom | D000086382;D047928 | T046;T047;T067 |
34,669,182 | cancer environ project four first nation organ work togeth address concern carcinogen environ first nation peopl human health well interconnect healthi environ first nation organ common rais concern regard carcinogen environ howev case studi avail guidanc work participatori respect way help assess address concern | D002273;D009369 | T131;T191 |
34,669,180 | corticothalam connect aneurysm subarachnoid hemorrhag relationship disord conscious clinic outcom present exploratori analysi occurr earli corticothalam connect disrupt aneurysm subarachnoid hemorrhag sah correl clinic outcom | D017544;D019917;D057510;D002532;D013345 | T190;T047;T061;T046 |
34,669,177 | best clinic practic guidanc clinician deal children present molar incisor hypomineralis mih updat european academi paediatr dentistri polici document updat exist european academi paediatr dentistri eapd polici document best clinic practic guidanc clinician deal children present molar incisor hypomineralis mih | D003744;D010377 | T091;T047 |
34,669,176 | effici safeti eltrombopag multi line fail chines patient immun thrombocytopenia case decreas megakaryocyt respons well singl center experi immun thrombocytopenia itp defin use intern consensus guidelin platelet count l absenc caus disord may associ thrombocytopenia patient without respons first line treatment refractori tpo receptor agonist ra ideal choic studi evalu effici safeti eltrombopag multi line fail chines patient immun thrombocytopenia itp analyz possibl factor may contribut differ base person characterist thirti five multi line fail itp patient receiv eltrombopag treatment enrol retrospect first affili hospit zhejiang chines medic univers januari august general inform peripher hemogram chang count bone marrow megakaryocyt mk peripher cell subset record respons advers effect evalu result show overal complet partial respons rate n n n respect eltrombopag center overal respons rate patient decreas mk unexpect higher patient increas normal mk count respect patient poorer eltrombopag respons group nk cell found peripher blood patient decreas mk higher level helper th cell regulatori treg cell nine eltrombopag relat advers event report common upper respiratori tract infect elev alanin transaminas alt venous thrombosi conclus studi reveal itp patient decreas megakaryocyt respond well eltrombopag abnorm nk cell may play role patient poor eltrombopag respons | D016553;D013921 | T047 |
34,669,175 | effect respons mechan load knee mechan load knee joint result differenti respons base local capac tissu ligament tendon meniscus cartilag bone tissu subsequ adapt load molecular cellular level particip cut pivot jump sport predispos knee risk injuri narrat review describ differ mechan load result excess load knee lead ligament musculotendin menisc chondral injuri maladapt follow injuri surgeri structur around knee primari goal rehabilit maxim patient respons exercis current level function minim risk injuri heal tissu clinician clear understand specif injur tissu rehabilit driven knowledg tissu heal constraint knee complex lower extrem biomechan neuromuscular physiolog task specif activ involv weight bear non weight bear condit train principl provid practic applic prescrib load progress exercis function activ mobil task base mechan load profil knee specif structur rehabilit process various load intervent use clinician produc physic stress address bodi function physic impair activ limit particip restrict modifi mechan load element clinician alter tissu adapt facilit motor learn resolv correspond physic impair provid differ load creat variabl tensil compress shear deform tissu mechanotransduct specif promot appropri stress adapt increas tissu capac injuri toler tool monitor rehabilit train load knee propos assess reactiv knee joint mechan load monitor excess mechan load facilit optim rehabilit | D007718;D040542 | T044;T037 |
34,669,174 | associ mood disord frequent emerg depart use cross section studi frequent emerg depart ed use grow problem associ poor patient outcom increas health care cost object analyz associ mood disord incid frequent ed use | D004636;D019964 | T048;T093;T073 |
34,669,173 | erector spina plane block acut pain manag emerg depart patient rib fractur rib fractur repres signific caus morbid mortal trauma patient erector spina plane block come forefront potenti safe effect option analgesia pain condit thorax multipl dermatom level given high morbid associ rib fractur inadequaci opioid analgesia strong safeti profil erector spina plane block pilot studi sought address whether block use safe effect provid analgesia emerg depart ed patient acut rib fractur | D009407;D012253 | T037;T061 |
34,669,172 | kartogenin promot bmscs chondrogen differenti osteoarthr regul mir p target smad pathway transplant mesenchym stem cell mscs potenti therapeut strategi cartilag degener osteoarthr oa control chondrogen differenti implant mscs joint remain challeng role kartogenin kgn chondrogenesi mscs wide report howev mechan chondrogenesi elucid oa | D059630;D035683;D010003 | T025;T047;T114;T123 |
34,669,170 | gender investig african climat chang research systemat review literatur systemat review analyz studi publish web scienc gender climat chang africa strong methodolog bias compar case studi sex disaggreg analys predomin limit set countri mani articl cover agrarian sector compar women men farm vulner chang climat base adapt behaviour though literatur recogn women import conserv farm food respons oftentim general contribut without provid evid number theme cover limit number articl includ coastal area conflict educ energi migrat urban area water overal justic orient research need socioeconom structur intersect social ident make certain peopl place institut vulner investig power dynam social scientist african institut also need articl review stem north america europ lock beyond paywal | D057231;D000085402 | T070;T054;T055 |
34,669,169 | cascad loss loss risk multipli amid chang climat pacif island human societi experienc continu experi extens loss damag worsen anthropogen climat chang despit natur tendenc categoris organis unhelp delin clean boundari linear understand complex messi concept loss damag draw perspect local region pacif island stakehold underexplor resourc understand loss damag explor complex interconnected non econom loss damag neld accord particip pacif island worldview knowledg system cosmolog often make difficult separ evalu neld independ challeng nomenclatur neld categori develop intern mechan instead neld understand often centr interdepend loss includ cascad flow effect occur natur loss risk multipli ie one loss creat risk loss notabl loss biodivers ecosystem servic land critic link cascad effect livelihood knowledg way life wellb cultur heritag argu loss damag alway absolut neld arguabl repar concern howev biodivers loss risk multipli consid least repar particip put forward neld understand must consid interconnect biodivers ecosystem conserv restor must focus intervent prevent irrepar cascad loss climat chang pacif island | D003247;D017753 | T082;T064;T078;T081;T070;T069 |
34,669,168 | case earli onset cystinuria month old girl cystinuria autosom recess disord character decreas reabsorpt cystin dibas amino acid lysin ornithin arginin renal proxim tubul present recurr urolithiasi cystinuria account pediatr urolithiasi age onset typic year report case earli onset cystinuria month old girl present hematuria notic multipl renal calculi ultrasonographi abdomin computer tomographi scan diagnosi cystinuria urinari calculus analysi urinari amino acid analysi patient treat urin alkalin cystin chelat drug gene analysi show pl heterozyg mutat mother av heterozyg mutat father slca gene gene encod putat subunit neutral basic amino acid transport protein bat although cystinuria autosom recess diseas previous report pl heterozyg mutat great suppress cystin reabsorpt caus cystinuria symptom therefor high influenti pl mutat slca gene may contribut onset autosom recess diseas extrem young age | D003555;D007669 | T047 |
34,669,167 | analysi progress disc degener distal unfus segment evalu long term function outcom adolesc idiopath scoliosi patient undergo long segment instrument fusion analys progress disc degener distal unfus lumbar segment post oper adolesc idiopath scoliosi ai patient evalu pre oper post oper radiolog paramet associ progress disc degener | D055959;D012600;D013123 | T190;T047;T061 |
34,669,166 | creat cell model use patient sampl carri pathogen mitochondri dna mutat ipsc approach lhon leber hereditari optic neuropathi preval mitochondri neurolog diseas caus mutat mitochondri dna encod respiratori complex subunit although genet origin leber hereditari optic neuropathi identifi year ago under pathogenesi still unclear primarili due lack relev system cell model current model limit lymphoblast fibroblast cybrid cell line diseas phenotyp limit retin ganglion cell induc pluripot stem cell serv excel model studi tissu specif diseas elucid under molecular mechan identifi novel therapeut target describ detail protocol generat retin ganglion cell also cardiomyocyt proof ipsc pluripot | D057026;D029242 | T025;T047 |
34,669,164 | mobil pcr base surveil sar cov reduc visit restrict nurs home covid pandem pilot studi resid nurs home elder nh high risk death covid investig whether repeat non mandatori rt pcr sar cov surveil nh staff visitor reduc covid incid rate nh resid allow reduc visit restrict | D000086382;D000086402 | T047;T005;T067 |
34,669,162 | effect extend shutdown measur bundesnotbrems introduc third sar cov wave germani third sar cov infect wave affect germani march april th bundesnotbrems introduc nationwid shutdown measur bundesnotbrems technic term use german govern describ nationwid shutdown measur control rise infect number measur includ main contact restrict sever level studi investig effect local dispers pre post bundesnotbrems measur infect dynam analyz variabl strength rate chang week case number consid differ region age group contact restrict region divers measur slow rate week increas region stronger contact restrict bundesnotbrems induc coher reduct infect number across german feder state age group throughout may coher infect dynam bundesnotbrems indic stronger measur induc decreas infect number region divers non pharmaceut intervent could deceler spread prevent alon | D000086382;D000086402 | T047;T005;T067 |
34,669,161 | co exist two leaf feed biolog control agent lantana camara alter herbivori semi field condit interact two biolog control agent releas lantana camara l sensu lato verbenacea studi replic semi field plot cage plant semi field condit inocul uroplata girardi pic coleoptera chrysomelida ophiomyia camara spencer diptera agromyzida either alon combin investig extent co infest two agent affect reproduct capac growth host end trial singl combin attack two agent effect stem diamet stem height canopi width howev uncag control plant heavili attack teleonemia scrupulosa stl hemiptera tingida therefor becam signific shorter cage plant treatment confin alon feed damag camara result higher reduct fruit flower biomass relat caus u girardi alon howev confin alon u girardi caus higher reduct leaf densiti fruit biomass combin camara singl attack camara caus higher reduct flower biomass simultan attack agent ground biomass singl combin treatment plant signific lower cage control plant uncag control plant expos heavi attack scrupulosa produc flower fruit ground biomass signific lower cage control plant overal studi show simultan attack two herbivor alter herbivori therebi affect reproduct capac growth host | D001517;D032410 | T204;T002 |
34,669,159 | two pituitari neuroendocrin tumor pitnet high prolifer tp mutat high grade pitnet pitnec report two pituitari neuroendocrin tumor pitnet high ki label indic mani mitos tp mutat near tumor cell nuclei posit p one tumor bone liver metastas one corticotroph cell tumor lactotroph tumor classif tumor subject discuss tradit pituitari carcinoma diagnos demonstr metastas accord classif contrast neuroendocrin neoplasm gastrointestin tract pancrea classifi either well differenti net grade g g g base prolifer determin ki indic andor reclassifici pitnet opinion adequ term well differenti corticotroph tumor report pitnet g wherea undifferenti prolactin tumor classifi pitnec report expand spectrum pituitari neuroendocrin neoplasm | D018358;D010911 | T191 |
34,669,158 | relat import cooper context kinship structur cooper behavior compar studi saami reindeer herder kin relat strong theoret empir basi explain cooper behavior nevertheless grow recognit context cooper environ individu also shape willing individu cooper nomad pastoralist norway cooper among kin non kin essenti predictor success northern part countri character histori herder herder competit exacerb herder conflict lack trust subsequ coordin problem contrast histori herder farmer competit southern norway character high level herder coordin trust compar studi investig relat import cooper context kinship structur cooper behavior use experiment gift game main find studi south high level cooper around individu push gift distribut even among herder nevertheless kinship matter sinc close kin give receiv larger gift contrast kinship seem main factor affect gift distribut north herder north also concern distribut gift equal albeit limit close kin level intragroup cooper drive gift distribut even among close relat herder observ region contrast cooper decis fit differ histor level conflict trust two region wherea herder south affect cooper context kinship kinship seem main determin cooper north | D003299;D012053 | T015;T054 |
34,669,157 | rapamycin enhanc anti tumor activ cabozantinib cmet inhibitor resist hepatocellular carcinoma cabozantinib main target cmet vascular endotheli growth factor receptor second line treatment patient advanc hepatocellular carcinoma hcc howev lower respons rate resist limit endur clinic benefit studi found cmet low hcc cell show primari resist cmet inhibitor combin cabozantinib mammalian target rapamycin mtor inhibitor rapamycin exhibit synergist inhibitori effect vitro cell prolifer vivo tumor growth cell mechan combin rapamycin cabozantinib result remark inhibit akt extracellular signal regul protein kinas mtor common downstream signal molecul receptor tyrosin kinas decreas cyclin express induc cell cycl arrest meanwhil rapamycin enhanc inhibitori effect cabozantinib migrat tubul format human umbil vascular endotheli cell human growth factor induc invas cmet inhibitor resist hcc cell hypoxia condit effect valid xenograft model conclus find uncov potenti combin therapi cabozantinib rapamycin combat cabozantinib resist hcc | D000813;D006528;D008113;D011725;D020123 | T191;T121;T109;T195 |
34,669,156 | chidamid inhibit notch myc signal axi cell acut lymphoblast leukemia cell acut lymphoblast leukemia one danger hematolog malign high tumor heterogen poor prognosi patient carri notch gene mutat lead abnorm express downstream target gene aberr activ various signal pathway found chidamid hdac inhibitor exert antitumor effect cell line primari cell includ anti notch activ particular chidamid inhibit notch myc signal axi regul level intracellular form notch nicd well myc part ubiquitin degrad proteasom pathway also report preliminari result clinic trial support treatment chidamid reduc minim residu diseas mrd patient well toler result highlight effect safeti chidamid treatment patient includ notch mutat open way new therapeut strategi patient | D054218 | T191 |
34,669,155 | character chromatin access psoriasi patholog hallmark psoriasi involv alter cell gene associ transcript level determin chromatin access howev extent alter cell transcript level recapitul epigenet featur psoriasi remain unknown systemat profil chromatin access th th th th treg cell found chromatin remodel contribut signific pathogenesi diseas chromatin remodel tendenc differ subtyp th cell relat consist next profil chromatin access transcript dynam memori thtreg cell memori th cell increas decreas chromatin access region identifi memori treg cell increas decreas chromatin access region identifi total gene differenti express peak associ memori th treg cell fosl spi atf nfkb runx etv erg fli etc identifi regul develop psoriasi transcript regulatori network show nfkb rela high connect central network nfkb regul gene ccl cxcl ilrn result provid candid transcript factor foundat framework regulom diseas | D002843;D011565 | T116;T047 |
34,669,154 | practic manag patient hematolog diseas covid pandem japan polymeras chain reaction pcr test alway detect sar cov virus possibl due differ sensit sampl type circumst immunochromatographi may serv altern method detect anti sar cov igg antibodi indic histori infect analysi patient sever covid infect found serum sampl posit igg antibodi wherea sampl patient asymptomat mild case negat two patient immun thrombocytopenia treat prednisolon experienc aggress covid relat respiratori failur eventu die patient remiss receiv steroid base chemotherapi higher risk death patient lymphoid malign includ lymphoma myeloma die larger number myeloid malign stricter cohort strategi base repeat pcr test isol privat room adopt routin care hematolog depart prevent viral spread environ | D000086382 | T047;T067 |
34,669,151 | human esc deriv neuromesoderm progenitor nmps success differenti mesenchym stem cell mscs mesenchym stem cell mscs adult stem cell type use treat various disord clinic howev deriv homogen adequ amount mscs limit regen treatment potenti although mesoderm main sourc mesenchym progenitor embryon develop neuromesoderm progenitor nmps resid primit streak develop known differenti paraxi mesoderm current studi generat nmps human embryon stem cell hesc subsequ deriv mscs character cell popul vitro vivo use bfgf chir induc nmp format protocol follow serum contain cultur condit show mscs generat nmps identifi express tbra sox also flk pdgfr studi nmp deriv mscs plastic adher fibroblast like cell coloni form capac trilineag osteo chondro adipo genic differenti potenti present studi demonstr nmp deriv mscs endotheli tendenc might relat flk pdgfr nmp origin nmp deriv mscs display protein express profil character mscs growth factor angiogenesi relat pathway protein similar express nmp deriv mscs character mscs nmp deriv mscs keep characterist short term long term freez thaw cycl local bone marrow follow tail vein inject nodscid mice togeth data show hesc deriv nmps might use precursor cell popul msc deriv could use vitro vivo research | D059630;D020796 | T025;T116;T192;T126 |
34,669,150 | metabolom analysi reveal adapt p przewalskii se depriv environ procapra przewalskii inhabit selenium se depriv environ long term patholog manifest due se depriv studi aim reveal under adapt induc se depriv analysi total signific chang metabolit identifi posit negat ion mode includ upregul downregul compound se depriv group differenti metabolit annot major molecul bile acid biosynthesi biosynthesi unsatur fatti acid pyrimidin metabol respect studi systemat analyz serum metabolom characterist p przewalskii se depriv condit first time provid basi understand metabol mechan p przewalskii se depriv environ | D012643 | T121;T196;T123 |
34,669,149 | enhanc photosynthet nitrogen use effici increas nitrogen alloc photosynthet machineri cotton domest domest involv dramat phenotyp physiolog diversif due success select breeder toward high yield qualiti although photosynthet nitrogen use effici pnue major trait understand leaf nitrogen economi unclear whether pnue cotton improv domest investig effect domest nitrogen alloc photosynthet machineri pnue wild domest cotton genotyp result show domest genotyp higher nitrogen content per mass n net photosynthesi satur light sat pnue similar nitrogen content per area n compar wild genotyp expect genotyp pnue posit relat sat negat correl n howev relat contribut sat pnue greater contribut n domest genotyp higher nitrogen alloc light harvest n l nitrogen light harvest chlorophyl protein complex bioenerget n b total nitrogen cytochrom f ferredoxin nadp reductas coupl factor rubisco n r wild genotyp howev two genotyp group differ pnue p ratio sat n p sum n l n b n r result suggest nitrogen alloc photosynthet machineri boost sat cotton domest improv effici nitrogen use photosynthet machineri might futur aim enhanc sat cotton | D000071278;D009584 | T123;T196;T078 |
34,669,148 | complet genom thermophil purpl sulfur bacterium thermochromatium tepidum compar allochromatium vinosum chromatiacea complet genom sequenc thermophil purpl sulfur bacterium thermochromatium tepidum strain mc dsm describ contrast mesophil relat allochromatium vinosum strain dsm chromatiacea tch tepidum genom singl circular chromosom base pair plasmid substanti smaller genom alc vinosum tch tepidum genom encod two form rubisco contain nifhdk sever gene encod molybdenum nitrogenas lack gene encod protein assembl fe cluster requir form function nitrogenas molybdenum iron cofactor leav phototroph phenotyp nif tch tepidum contain gene necessari oxid sulfid sulfat photosynthet electron donor genet unequip either oxid thiosulf electron donor carri assimil sulfat reduct physiolog hallmark alc vinosum also unlik alc vinosum tch tepidum oblig phototroph unabl grow chemotroph dark respir sever gene present alc vinosum genom absent genom tch tepidum like contribut major physiolog differ observ relat purpl sulfur bacteria inhabit distinct ecolog nich | D002841 | T007 |
34,669,147 | mitochondri dna sequenc variat risk meningioma risk factor meningioma includ femal gender african american race high bodi mass index bmi exposur ioniz radiat although genom wide associ studi gwas identifi two nuclear genom risk loci meningioma rs rs relat mitochondri dna mtdna sequenc variant meningioma unknown | D008577;D008579 | T191 |
34,669,145 | approach assess adjust select outcom report meta analysi select non report studi outcom result outcom report bias | D017594 | T080 |
34,669,143 | alter plasma fatti acid associ gut microbi composit common variabl immunodefici fatti acid fa abnorm found various inflammatori disord relat disturb gut microbiota patient common variabl immunodefici cvid inflammatori complic associ alter gut microbi composit hypothes alter fa profil cvid patient relat gut microbi dysbiosi | D017074;D015525;D000069196 | T007;T047;T121;T109;T123;T001 |
34,669,141 | sexual health relat care need among young adult cancer patient survivor systemat literatur review young adult cancer patient survivor age specif care need care need relat sexual health poor understood systemat literatur review conduct examin sexual health relat care need among patientssurvivor diagnos cancer young adulthood age year preval type need assess along associ patient factor | D009369;D000074384 | T032;T191 |
34,669,138 | associ among sentinel surveil meteorolog factor infecti diseas gwangju korea outbreak new infecti diseas threaten human surviv transmiss diseas determin sever factor climat import factor studi conduct assess correl occurr infecti diseas climat factor use data sentinel surveil system meteorolog data gwangju jeollanam republ korea climat gwangju june septemb humid citi highest averag temperatur wherea decemb februari cold dri infect rate salmonella temperatur r relat humid r e coli r r rotavirus r r norovirus r r influenza virus r r coronavirus r r coxsackievirus r r shown high correl season chang specif meteorolog factor pathogen show distinct season occurr infect observ high correl climat characterist gwangju particular viral diseas show strong season research matter need due current covid pandem quarantin prevent becom import block spread infecti diseas purpos studi predict infect various type data relat infect import | D000086382;D003141 | T047;T067 |
34,669,137 | preferenti remov benzen toluen ethylbenzen xylen btex persulf ethanol contain aquif materi effect approach elimin impact ethanol biodegrad benzen toluen ethylbenzen xylen btex concern bioremedi groundwat contamin ethanol blend gasolin situ chemic oxid isco common techniqu wide use remedi contamin groundwat howev select isco btex ethanol remov poor understood therefor batch experi perform differ aquif materi includ calcar soil basalt soil granit soil dolomit sand gasolin use provid dissolv btex ethanol reagent use addit improv qualiti gasolin reduc possibl air pollut caus gasolin persulf ps use chemic oxid oxid organ contamin target concentr btex ethanol mgl mgl respect result show ethanol could preferenti degrad absenc ps inhibit btex biodegrad howev btex could preferenti remov prior ethanol aquif materi use ambient temperatur ps ad psbtex molar ratio btex sand dolomit granit soil preferenti remov first order decay rate constant day within first day follow calcar basalt soil constant day ethanol could compet btex sulfat radic first order decay rate constant day first day slower btex ph quick decreas calcar soil rich organ matter calcar basalt soil inhibit effect btex oxid ps ph buffer calcar soil may impli potenti ps oxid combin bioremedi carbon rock region | D060587;D014992 | T082;T121;T109;T130;T081;T070 |
34,669,136 | effect polypropylen polyvinyl chlorid polyethylen terephthal polyurethan high densiti polyethylen polystyren microplast nelumbo nucifera lotus water sediment plastic wast recognis hazard risk increas polym break natur secondari microplast even nanoplast number studi report preval microplast everi perceiv nich bioavail biota dramat increas knowledg ecotoxicolog microplast advanc well howev inform regard plant specif aquat macrophyt still lack present studi aim gain inform ecotoxicolog effect six differ polym type mm microplast morpholog germin growth physiolog catalas glutathion transferas activ root aquat macrophyt nelumbo nucifera role sediment also consid conduct exposur sediment contain sediment free exposur system polyvinyl chlorid polyurethan exposur caus highest inhibit germin growth compar control howev presenc sediment signific decreas advers effect catalas activ increas exposur polyvinyl chlorid polyurethan polystyren presenc absenc sediment sediment free system glutathion transferas activ signific increas exposur polypropylen polyvinyl chlorid polyethylen terephthal sediment free system exposur polyethylen terephthal polyurethan absenc sediment clear correl morpholog physiolog effect observ studi requir understand under toxic mechan microplast | D000070116;D031653;D014874 | T131;T002 |
34,669,135 | construct cleaner product manag system china mode innov cleaner product studi base practic cleaner product cp audit enterpris review cp option found option direct indirect relat manag moreov common problem poor sustain cp audit result show enterpris manag play signific role implement cp option base studi propos new concept cleaner product manag cpm system draw lesson modern environment manag theori method establish framework cpm system system combin theori method cp manag system enterpris present cpm requir current enterpris manag system main includ cpm respons cp object cpm index cp energi resourc manag cp process control cp product manag cpm inspect cp perform evalu characterist propos system construct modern inform base cpm system high systemat concis structur easi oper system simplifi improv cp work enterpris reduc sever tedious task document prepar also enhanc enterpris manag effici motiv willing employe particip cp innov develop cp implement system implement appli chines enterpris implement applic obvious effect improv product level well environment econom benefit | D003247;D004777;D008330 | T082;T064;T078;T081;T067;T058;T069 |
34,669,134 | impact uncertainti region carbon peak path analysi base carbon emiss account model drive factor region carbon emiss path import impact realize china carbon emiss peak target due uncertainti futur develop model chang carbon emiss also face uncertainti make achiev peak target challeng take shandong henan guangdong three china popul provinc exampl studi analyz impact uncertainti carbon account principl drive factor simul mechan achiev peak target result show baselin scenario account principl base primari energi consumpt ipcc sector consumpt make peak time guangdong evalu respect simul base ipcc sector account advanc peak time shandong least year henan less affect consid impact energi structur guangdong henan estim peak without consid impact energi structur peak two provinc may energi structur effect estim peak time shandong addit k valu ridg regress method also effect peak time three provinc affect simul annual carbon emiss studi also present carbon emiss trajectori differ scenario simul result environment regul measur acceler industri structur transform increas energi consumpt intens may help achiev peak carbon emiss target soon possibl also suggest uncertainti includ futur carbon assess present complet carbon emiss trajectori | D002244;D002245 | T197;T121;T196;T123 |
34,669,132 | prepar sludg base materi environment friend applic wastewat treatment heterogen oxid technolog sludg resourc util high valu ad develop environment friend mean sludg treatment rich organ substanc metal content sludg replac activ carbon becom wide use carbon base materi sludg base activ carbon sbac meanwhil heterogen catalyst sludg base catalyst sbc solv requir tradit fenton catalyst ph metal ion leach catalyst recycl paper combin properti sbacsbc characterist three method activ support hydrotherm prepar sbacsbc review general necessari select appropri prepar method base pollut environment treatment goal furthermor compar catalyst sbc heterogen oxid obvious advantag refractori organ pollut reaction mechan usual involv oh process final possibl direct futur research involv environment friend sbacsbc propos | D012722;D018508 | T052;T069;T057 |
34,669,131 | associ exposur air pollut risk inflammatori bowel diseas visit topic inflammatori bowel diseas ibd attract attent accumul evid suggest exposur air pollut associ ibd yet result inconsist studi daili exposur studi evalu associ daili air pollut ibd hefei china daili ibd admiss data obtain two hospit hefei januari decemb daili concentr major air pollut provid hefei environment protect bureau meteorolog data collect china meteorolog data network distribut lag nonlinear model dlnm consid lag effect exposur factor nonlinear relationship exposur reaction use assess effect daili air pollut exposur ibd admiss studi period total case ibd recruit includ case ulcer coliti uc case crohn diseas cd find show pm co exposur signific increas risk ibd mean concentr pm co hefei ugm ugm mgm respect increas mgm pm mgm co increas risk ibd strongest effect three pollut ibd observ lag lag rr ci lag rr ci lag rr ci respect warm season pm co stronger effect increas risk ibd observ lag rr ci lag lag rr ci rr ci lag rr ci respect air pollut pm co exposur could increas risk ibd suscept season exposur main warm season result studi suggest air pollut increas risk ibd patient hefei china provid basi develop countri improv effect prevent ibd potenti opportun avoid part risk onset recurr ibd studi contribut knowledg associ air pollut ibd associ need verifi studi | D000393;D000397;D015212 | T131;T069;T080;T047 |
34,669,129 | effect reclaim water irrig soil characterist microbi popul plant rhizospher paper effect irrig differ water qualiti soil characterist kind garden plant analyz result show soil ph rang signific differ differ soil compar contrast treatment reclaim water irrig content soil total salin chlorid ion water solubl sodium soil plant averag higher tap water respect influenc reclaim water irrig soil nutrient chang type plant content soil organ matter avail potassium show signific differ plant compar tap water irrig content alkalin nitrogen plant increas averag year irrig reclaim water term soil microorgan increas soil microbi popul includ bacteria fungus actinomycet promot differ level reclaim water irrig close relat soil nutrient | D012987;D012989 | T167;T131 |
34,669,127 | endotheli progenitor cell overexpress platelet deriv growth factor facilit deep vein thrombosi resolut assess therapeut efficaci pdgf overexpress endotheli progenitor cell epc deep vein thrombosi inferior vena cava thrombosi induc femal spragu dawley sd rat anim inject via distal vena cava epc overexpress pdgf transfect lentivir vector contain pdgf gene effect thrombosi anim receiv epc evalu use msb stain immunohistochemistri immunofluoresc venographi steadi state mrna protein level pdgf receptor pdgf r determin rt pcr western blot respect pdgf induc mobil circul epc estim flow cytolog compar control inject epc overexpress pdgf associ increas thrombosi resolut recan pdgf pdgf r express induct monocyt home mobil epc venous circul rat model transplant pdgf overexpress epc facilit resolut deep vein thrombosi | D066026;D013927;D020246 | T025;T046;T047 |
34,669,126 | exogen phytohormon regul growth develop cereal abiot stress abiot stress among extrem temperatur salin drought uv radiat heavi metal pollut etc advers affect growth yield cereal import group monocotyledon plant met nutrit need mankind thousand year cope stress plant deploy certain adapt strategi combin morpholog physiolog biochem respons growth product depend import place format strategi occupi phytohormon signal biomolecul differ chemic structur physicochem properti act nanomolar concentr regul physiolog metabol process plant review latest literatur data concern growth develop regul exogen phytohormon cereal abiot stress analyz summar effect prime foliar treatment abscis acid gibberellin auxin cytokinin brassinosteroid jasmon salicyl acid cultiv cereal toler differ abiot stressor discuss peculiar bilater multilater hormon signal format respons cultiv cereal abiot stressor applic exogen phytohormon consid issu exogen phytohormon effect molecular mechan control synthesi endogen hormon signal activ singl emphas phytohormon engin open new opportun increas yield seen import promis approach overcom cereal loss caus advers extern factor | D063245;D018521;D013312 | T121;T039;T046;T032;T040;T038 |
34,669,123 | review interplay obes lipoprotein profil nutrigenet select candid marker gene type diabet mellitus type diabet mellitus rapid grow epidem frequent relat complic demand global attent two factor common attribut epidem genet factor environment factor studi indic genet makeup individu level environment aspect influenc occurr diseas howev insuffici understand mechan gene mutat environment compon individu lead tdm also discrep often note associ gene variant type diabet gene factor examin sole attribut diseas | D005786 | T045 |
34,669,122 | altern explan alzheim diseas parkinson diseas initi specif antibiot gut microbiota dysbiosi neurotoxin late onset neuropatholog includ alzheim diseas parkinson diseas becom increas preval causat link genet gut microbiota dysbiosi gut dysbiosi autoimmun diseas pathogen exposur neurotoxin altern explanatori hypothesi provid pathogenesi virtual everyon pervas daili exposur neurotoxin inhal skin contact direct blood transmiss gastrointestin tract ingest result everi individu substanti fluctuat neurotoxin blood level two major barrier neurotoxin entri central nervous system blood brain barrier intestin wall absenc gut dysbiosi inflamm gut dysbiosi induc antibiot usag increas intestin wall permeabl neurotoxin reach bloodstream also increas blood brain barrier permeabl neurotoxin gut dysbiosi includ gut dysbiosi caus antibiot treatment especi high risk neurotoxin entri brain caus late onset neuropatholog gut dysbiosi far reach immun system central nervous system effect even transient gut dysbiosi act combin neurotoxin aluminum mercuri lead arsenic cadmium selenium manganes organophosph pesticid organochlorin reach neurotoxin blood level initi late onset neuropatholog depend individu age genet vulner | D000544;D000069196;D010300 | T048;T047;T007;T001 |
34,669,121 | correl pre race anxieti use general anxieti disord item scale estim million adult unit state diagnos anxieti disord make common psychiatr disord countri although data conflict limit engag increas exercis propos manag anxieti mental health disord purpos studi determin correl pre race anxieti run experi sex bodi mass index age mental health histori use valid general anxieti disord item screen tool anxieti studi prospect trial adult runner schedul particip k k half marathon full marathon race particip complet survey consist epidemiolog variabl general anxieti disord item screen tool result reveal runner experi increas mileag demonstr decreas report worri daili near daili basi whether find correl decreas risk develop anxieti disord yet determin base find exercis prescript treatment possibl prevent anxieti consid | D001008;D012420 | T048;T056 |
34,669,120 | pathway care help seek behavior relat durat untreat psychosi treatment engag much research focus relationship durat untreat psychosi dup clinic outcom first episod psychosi fep patient popul littl known individu help seek episod hse patient undergo receiv appropri care purpos project better understand earli referr fep specif care support system differ affect patient dup engag treatment data patient analyz earli psychosi intervent clinic new orlean epic nola use modifi version pathway care assess data captur clinic care patient first hse lead referr epic nola sd shorter dup compar patient refer two hses sd p ci one chi squar test reveal signific greater proport patient refer one hse stay treatment month cluster analysi independ test analys reveal patient hospit pathway sd signific longer dup compar self hospit sd care pathway studi support exist literatur suggest earli fep treatment lead shorten dup longer treatment engag addit patient support system peopl servic assist help seek reach epic nola faster shorter dup better treatment engag | D000066505;D011618 | T048;T055 |
34,669,119 | independ psychometr evalu predict util social anxieti questionnair social anxieti questionnair saq item measur social anxieti develop comprehens concis target mechan describ clark well model social anxieti address breadth social anxieti symptom may encompass exist questionnair aim current studi independ investig factor structur saq ie studi determin predict valid util ie studi data collect across studi evalu factor structur util overal result suggest total sum score saq appear captur uniqu aspect social anxieti may captur use singl measur appear provid util experiment manipul theoret mainten factor current studi limit conveni sampl futur research continu document psychometr properti clinic util novel measur social anxieti saq may show promis correl experiment research futur research consid evalu util | D001007;D005239 | T048;T184;T041 |
34,669,114 | prognost valu alp ldh periampullari carcinoma patient undergo surgeri convers normal cell cancer cell often accompani abnorm synthesi serum enzym alkalin phosphatas alp lactat dehydrogenas ldh report prognost valu varieti malign aim studi investig effect preoper serum alp ldh level prognosi patient periampullari carcinoma underw pancreatoduodenectomi pd | D002277;D004067 | T191 |
34,669,113 | adjuv chemotherapi versus radiotherapi high risk earli stage endometrioid endometri carcinoma present studi design evalu effect adjuv chemotherapi ct vs radiotherapi rt alon combin ct prognosi patient high risk earli stage stage stage ii endometrioid endometri carcinoma | D009367;D017063 | T057;T185;T060;T081;T062 |
34,669,112 | role machin learn method synthesi biolog nvestig heterocycl compound machin learn ml method attract increas interest chemistri field scienc recent year method great import design target bioactiv compound especi avoid loss time money chemic lot onlin web base platform libsvm ochem applic ml method paper examin literatur data activ predict heterocycl compound biolog activ result antiureas hiv integras e coli dna gyras b antifung pharmacophor base studi synthesi find possibl inhibitor use differ machin learn method | D006571;D021281 | T109;T081 |
34,669,111 | structur distinct sk ribosom inactiv protein jatropha curca biolog activ ribosom inactiv protein rip group protein exhibit n glycosidas activ lead inactiv protein synthesi thirteen predict jatropha curca rip sequenc could group rip type express rip gene detect seed kernel seed coat leav full length cdna two rip gene sk sk clone studi sk protein success express host cell difficult produc even small amount sk protein therefor crude protein use e coli express sk sk construct show rip activ cell lysat sk could inhibit growth e coli addit crude protein extract sk express cell display effect growth mda mb human breast cancer cell line base silico analysi j curca rip contain rna ribosom p stalk protein bind site howev c termin region p stalk bind site lack sk structur addit amphipath distribut posit negat potenti observ sk protein similar found anti microbi peptid find suggest sk protein structur might contribut toxic suggest potenti use pathogen bacteria futur | D054788 | T116;T126 |
34,669,110 | predict micronucleus assay outcom use vivo activ data molecular structur featur vivo micronucleus assay wide use genotox test determin extent chromosom aberr caus chemic human be play signific role drug discoveri paradigm reduc uncertainti vivo experi expens intend develop novel machin learn base tool predict toxic compound high precis total compound known toxic inform retriev pubchem bioassay databas literatur fingerprint descriptor compound generat use padel chemsar respect analysi perform model assess use three tire evalu strategi fivefold tenfold valid extern dataset structur alert caus genotox compound identifi use sarpi method note fingerprint base random forest model built analysi abl demonstr highest accuraci tenfold cross valid essenc studi highlight structur alert chlorocyclohexan trimethylamin like lead caus toxic human inde believ random forest model generat studi appropri reduct test anim consid futur good practic anim welfar | D001681;D003198;D016208;D000069550;D015162;D008954 | T170;T059;T066;T075 |
34,669,109 | five year outcom sleev gastrectomi patient class obes type diabet mellitus sever studi report short medium term outcom laparoscop sleev gastrectomi lsg patient class obes type diabet mellitus tdm howev literatur outcom beyond three year scarc present studi discuss year result previous report cohort patient class obes tdm undergon lsg march march | D003924;D010535;D009767 | T061;T047;T060 |
34,669,108 | eleven new c diterpenoid alkaloid delphinium elatum cv pacif giant diterpenoid alkaloid main compon plant genera aconitum delphinium garrya group natur product notabl chemic properti biolog activ sever c diterpenoid alkaloid compon delphinium elatum cv pacif giant well deriv exhibit cytotox activ lung prostat cervic vincristin resist cervic cancer cell line current phytochem investig seed elatum cv pacif giant eleven new c diterpenoid alkaloid elapacilin meladin melapacitin iminoeladin oxopacilin oxopacinin n deethyldelphelin n deethylpacinin n deethyl oxoeladin n deethyl n formyleladin n deethyl n formyldelphelin togeth known c diterpenoid alkaloid isol structur elucid extens spectroscop method includ nmr ir ms hrms three known diterpenoid alkaloid dehydrodelcorin delelatin dehydroeldelidin isol first time plant six new c diterpenoid alkaloid three known diterpenoid alkaloid evalu cytotox activ five human tumor cell line | D031841;D000470;D031882;D004224 | T121;T002;T109;T123;T131 |
34,669,107 | efficaci medic therapi patient chronic kidney diseas heart failur preserv eject fraction systemat review meta analysi preval mortal heart failur preserv eject fraction hfpef high patient chronic kidney diseas ckd howev still lack recommend medic therapi patient guidelin far | D006333;D051436 | T047;T046 |
34,669,106 | characteris autophagi disrupt ileum pig infect lawsonia intracellulari lawsonia intracellulari aetiolog agent prolif enteropathi enter diseas endem swine surviv intracellular nich ileum epitheli line requir capac subvert repress exploit host immun respons creat environ conduc bacteri propag better understand l intracellulari surviv intracellular nich perform investig dynam relationship infect host autophagi respons immunohistochemistri experiment infect porcin ileum samplesbeclin protein requir earli autophagi pathway observ distribut basal apic concentr gradient crypt healthi piglet whilst infect piglet observ gradient distribut increas presenc beclin crypt histolog characterist l intracellulari resid detect microtubul associ protein light chain lc use method monitor autophagi progress associ matur autophagosom lc notabl chang signal intens crypt characterist l intracellulari infect healthi crypt uninfect pig final p degrad intern substrat autophagosom use measur autophag flux observ reduct redistribut pthese preliminari result autophagi respons ileum suggest l intracellulari affect autophagi disrupt host ileum homeostasi may provid mechan assist bacteri propag contribut pathogenesi | D045824;D020639;D013553 | T007;T047 |
34,669,105 | nanopor genom sequenc variant analysi suscept candida auri strain l salvador brazil candida auri report worldwid decemb first strain covid patient brazil isol describ genom sequenc suscept c auri strain perform variant analysi genet related strain geograph local | D000086382;D002177;D058608 | T082;T047;T067 |
34,669,104 | mix method investig diagnostician sexgend bias challeng assess femal autism spectrum disord despit import clinic judgement autism spectrum disord asd assess littl current known challeng face diagnostician client femal sexgend bias assess process issu affect diagnost outcom forti seven asd diagnostician complet questionnair contain two hypothet case studi male femal asd present sexgend random assign within diagnostician report greater asd symptom sever femal sexgend pseudonym alloc case studi confid asd diagnosi similar regardless condit diagnostician identifi larg number challeng associ assess femal asd mani relat sexgend differ asd present limit diagnost instrument | D000067877 | T048 |
34,669,101 | evalu effect abridg imnci day cours v standard day cours pakistan convent imci train healthcar provid deliv day expens disrupt normal clinic routin provid equal effect shorter train cours may address challeng | D002983;D006282 | T097;T080 |
34,669,100 | effect matern self regul motiv breastfeed continu women frequent report breastfeed problem earli postpartum period women self endors belief breastfeed benefit babi like continu breastfeed despit breastfeed barrier matern self endors belief key compon matern self regul motiv present studi examin associ matern self regul motiv breastfeed durat exclus chines women | D001942;D009042 | T055;T041;T058;T078;T040;T080 |
34,669,099 | percept health care inform social support among women affect zika virus infect pregnanc two us state understand inform need experi health care social support among women confirm possibl zika virus infect pregnanc | D011251;D000071244;D000071243 | T047;T005 |
34,669,098 | moringa oleifera supplement diet protect cortico hippocamp neuron degener scopolamin induc spatial memori deficit mice role oxido inflammatori cholinerg neurotransmiss pathway therapeut pharmacolog manag alzheim diseas ad general consid major concern ethnomedicin moreov plant base food contain flavonoid previous report show neuroprotect effect modul self aggreg amyloid tau peptid oligom fibril associ pathogenesi ad studi investig impact moringa oleifera supplement diet mo sd scopolamin induc spatial memori deficit mice mice partit two phase five group n pretreat intraperiton scopolamin mgkg prior daili oral administr mo sd day spatial memori function assess use morri water maze mwm test thereaft marker cholinerg system inhibit acetylcholinesteras ach oxido inflammatori stress malonaldehyd mda nitrit superoxid dismutas sod tumor necrosi factor alpha tnf histo morpholog cortico hippocamp neuron measur scopolamin treatment led loss spatial memori function mice spatial explor escap platform mwm test meanwhil treatment mo sd attenu loss spatial memori function via signific decreas escap latenc signific increas frequenc cross time spent platform quadrant furthermor scopolamin treatment alter endogen antioxid pro inflammatori mediat elev acetylcholinesteras activ promot chromatolysi cortico hippocamp neuron howev mo sd signific amelior oxido inflammatori stress restor cholinerg transmiss via acetylcholinesteras inhibit maintain neuron integr mice brain phase result suggest moringa oleifera supplement diet may serv potenti therapeut possibl pharmacolog macromolecul prevent loss neuron cell manag alzheim diseas | D029588;D012601 | T121;T002;T109 |
34,669,097 | exosom potenti player endotheli dysfunct cardiovascular diseas exosom spheric bilay membran vesicl averag diamet nm particl perform wide rang biolog activ due content includ protein nucleic acid lipid lncrna mirna exosom involv inflamm induct oxid stress apoptosi effect endotheli dysfunct due induct mention process endotheli cell intercellular connect destroy cell permeabl increas final cell effici decreas function defect occur cardiovascular diseas cvds consequ endotheli dysfunct thus identifi exosom signal pathway induc inflamm oxid stress apoptosi endotheli dysfunct subsequ cvds reduc exosom use appropri target therapi | D002318;D055354;D035683 | T026;T047;T114;T123 |
34,669,096 | identif women risk hereditari breast ovarian cancer among particip popul base breast cancer screen women attend mammographi screen may benefit famili histori fh assess identif hereditari breast ovarian cancer hboc studi explor efficaci tailor educ intervent drive attent fh associ risk among women compar efficaci two educ tool increas attent toward fh women negat mammographi random receiv note fh breastovarian cancer letter n note detail possibl implic fh pattern letter b n upon women request brief questionnair administ phone screen unit su select elig depth fh evalu genet unit gu affect relat score accord type cancer age diagnosi gender posit famili tree women contact su group group b adjor ci fh score women group b group adjor ci gu trace interview women offer person consult attend elig test test perform women brca pathogen variant found among mammograph screen attende educ materi simpl descript fh may improv self referr women deserv depth evalu hboc identif addit educ effort need enhanc effici intervent | D001943;D010051 | T191 |
34,669,094 | juvenil idiopath arthriti associ uveiti era biolog therapi diseas chang year observ tertiari referr center rome itali describ ophthalmolog characterist juvenil idiopath arthriti jia cohort evalu therapeut advanc chang cours uveiti | D001171;D014605 | T047 |
34,669,093 | ethic adultcentr context covid whose voic matter adultcentr inher featur social fabric compris resourc rich countri twenti first centuri undermin capac valu voic young peopl various way context covid confront question whose voic matter must ask adultcentr ethic permiss pandem critic controversi examin question relat evolv concept childhood children right capac young peopl highlight area tension futur research potenti critic dialogu | D000086382 | T047;T067 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.