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https://en.wikipedia.org/wiki/High%20Frequency%20Internet%20Protocol
High Frequency Internet Protocol (HFIP or HF-IP) is usually associated with Automatic Link Establishment and HF radio data communications. HFIP provides protocol layers enabling internet file transfer, chat, web and email. HFIP commonly uses ionospheric propagation of radio waves to form a wide area network that can span thousands of kilometers. HF transceivers in HFIP service typically run 20 to 150 watts for portable or mobile units, up to approximately 2000 watts transmitter output for high power base stations with HFIP servers. STANAG 5066 is a common HFIP standard. An amateur radio HFIP network called HFLINK uses Automatic Link Establishment for initiating data communications, with ARQ 8FSK frequency-shift keying and PSK phase-shift keying signals. References Internet protocols Amateur radio
https://en.wikipedia.org/wiki/Nuclepore%20filter
A nuclepore filter (brand name Nuclepore from Whatman, part of GE Healthcare) is a kind of filter in which holes a few micrometres in size have been created in a plastic (e.g. polycarbonate) membrane. These filters are generally created by exposing the membrane to radiation that weakens the plastic and creates specific areas that can be removed by dousing the membrane in acid (or other chemicals). The technique and patent were developed by Robert L. Fleischer, P. Buford Price, and Robert M. Walker as an outgrowth of their research on radiation effects in solids, with a special focus on materials exposed to energetic particles in space. The technique allows for creating uniform holes of any desired diameter to allow even a virus to be filtered. The most common use of Nuclepore filters is in microbiology where they are used to trap cells while removing all other fluids and smaller particles, e.g. for counting bacteria by fluorescence microscopy. Because the filters have a flat surface, the cells are trapped on top of the filter and remain visible, unlike other types of filters where the cells may be trapped inside the filter. See also Ion track. Footnotes Filters Membrane technology
https://en.wikipedia.org/wiki/Meusnier%27s%20theorem
In differential geometry, Meusnier's theorem states that all curves on a surface passing through a given point p and having the same tangent line at p also have the same normal curvature at p and their osculating circles form a sphere. The theorem was first announced by Jean Baptiste Meusnier in 1776, but not published until 1785. At least prior to 1912, several writers in English were in the habit of calling the result Meunier's theorem, although there is no evidence that Meusnier himself ever spelt his name in this way. This alternative spelling of Meusnier's name also appears on the Arc de Triomphe in Paris. References Further references Meusnier's theorem Johannes Kepler University Linz, Institute for Applied Geometry Meusnier's theorem in Springer Online Theorems in differential geometry
https://en.wikipedia.org/wiki/S.%20Mohinder
Bakshi Mohinder Singh Sarna (24 February 1925 – 6 September 2020), known professionally as S. Mohinder, was an Indian music composer. Early life He was born in Sillanwali Tehsil, Sargodha District in 1925. Mohinder’s father Bakhsi Sujan Singh was a sub-inspector in the police forces. Later, his father also served in Sahiwal (old name Montgomery area). He was a student of a famous musician at that time in Sahiwal named Pandat Ratan Moorti who lived at Babay Wala Chowk. His father Bakshi Sujan Singh was transferred and the family moved to a comparatively larger city Lyallpur, British India now Faisalabad, in Pakistan, where young Mohinder, in the 1930s, started an apprenticeship with an accomplished Sikh religious vocalist Sant Sujan Singh. He honed his skills for several years in accordance with classical music in the tutelage of Sant Sujan Singh. Initially, he strived to be a singer. Later, his family moved to Sheikhupura (now in Pakistan), close to Nankana Sahib, the birthplace of the founder of Sikhism (Guru Nanak). He later received his further training in classical music from Sikh religious musician Bhai Samund Singh. Frequent transfers of his father kept the family on the move. Since Mohinder’s education suffered, his father enrolled him in Khalsa High School during the 1940s in the village Kairon in Amritsar. S. Mohinder was fluent both in Urdu and Punjabi languages. It took him some time to learn the Hindi language. Career In 1947, the rest of his family moved to
https://en.wikipedia.org/wiki/Efts
Efts are newts in their terrestrial juvenile stage. EFTS, EFTs and similar may refer to: EFTS, a measure of student numbers EF-Ts, a biological protein Elementary Flying Training School, a type of Royal Air Force school in the UK Electronic funds transfers (EFTs), in banking Emotional Freedom Techniques, in alternative medicine See also EFT (disambiguation), for the singular
https://en.wikipedia.org/wiki/Jo%C3%ABl%20Vandekerckhove
Joël Vandekerckhove is a Belgian molecular biologist and professor at the University of Ghent (Ghent, Belgium). He is head of the VIB Department of Medical Protein Research, UGent. His research department works on functional proteomics: development and applications, molecular cell biology and biochemistry of the actin cytoskeleton, cell biology and biochemistry of the actin cytoskeleton, cytokine signalling, and molecular and metabolic signalling. Research at the department lead to the university spin off biotech company Peakadilly. Sources Department of Medical Protein Research Proteomics and Bioinformatics Group Joël Vandekerckhove Belgian molecular biologists Flemish scientists Year of birth missing (living people) Living people
https://en.wikipedia.org/wiki/Yursa
Yursa was a town from the 1350–1335 BC Amarna letters correspondence. The site, a city/city-state, is probably in the southern Canaan close to Gaza. Some scholars identify it with Tell Jemmeh. In the 382–letter correspondence it is the location of its mayor/ruler, Pu-Ba'lu, who authored 3 letters written to the pharaoh, namely EA , (EA for 'el Amarna'). The three letters to the pharaoh from Pu-Ba'lu of Yursa are: EA 314—Title: "A shipment of glass" EA 315—Title: "Like a command of the Sun"–See: Reanap EA 316—Title: "Postscript to the royal scribe"–See: Tahmašši Of the entire Amarna letters 382–letter corpus, Yursa is only referenced in letters 314, and 315, as: "..Pu-Ba'lu, the ruler of Yursa". Example letter of Yursa/Pu-Ba'lu EA 314, title: "A shipment of glass" "To the king (i.e. Pharaoh), my lord, my god, my Sun, the Sun from the sky: Message of Pu-Ba'lu, your servant, the ruler of Yursa. I indeed prostrate myself at the feet of the king, my lord, my god, my Sun: the Sun from the sky. 7 times and 7 times, on the back and on the stomach. I am indeed guarding the place of the king, (my) lord, my Sun, the Sun from the sky. Who is the dog that would not o]be[y the orders of the king, the Sun from the sk]y? [Since the king, my lord, has ord[ere[d] some glass, I [s]end it to the king, my lord, my god, the Sun from the sk[y]." EA-314, lines 1-22 (with damaged cuneiform characters) EA 235, entitled: "An order of glass", is of the same subject, a letter from Satatna of Akka-(
https://en.wikipedia.org/wiki/Pu-Ba%27lu
Pu-Ba'lu, (another spelling, also Pu-Bahla) was ruler/mayor of Yursa, (a city/city-state in Canaan(?)), identified with Tell Jemmeh, of the 1350–1335 BC Amarna letters correspondence. His name translates in west semitic as well as in Akkadian as: "word/mouth (of) Baal", the 'Spokesman (of) Baal' , (–or 'Baal's Voice'). Pu-Ba'lu of Yursa is the author of three letters to pharaoh. See: Yursa The three Amarna letters, (EA for 'el Amarna') to pharaoh from Pu-Ba'lu of Yursa are: EA 314—Title: "A shipment of glass" EA 315—Title: "Like a command of the Sun"–See: Reanap EA 316—Title: "Postscript to the royal scribe"–See: Tahmašši Of the entire Amarna letters 382–letter corpus, Pu-Ba'lu of Yursa is only referenced in letters 314, and 315, as: "..Pu-Ba'lu, the ruler of Yursa", and EA 316, as "Pu-Ba'lu". One other reference in EA 104, entitled: "Ullassa taken" is to Abdi-Ashirta's son, "Pu-Bahla", presumably a separate 'Pu-Baal'. Example letter of Pu-Ba'lu EA 314, "A shipment of glass" To the king-(i.e. Pharaoh), my lord, my god, my Sun, the Sun from the sky: Message of Pu-Ba'lu, your servant, the ruler of Yursa. I indeed prostrate myself at the feet of the king, my lord, my god, my Sun: the Sun from the sky, 7 times and 7 times, on the back and on the belly. I am indeed guarding the place of the king, (my) lord, my Sun, the Sun from the sky. Who is the dog g that would not o]be[y the orders of the king, the Sun from the sk]y? [Since the king, my lord, has ord[ere[d] some glass,
https://en.wikipedia.org/wiki/Nautilus%20%28video%20game%29
Nautilus is a video game for the Atari 8-bit family of home computers created by Mike Potter and published by Synapse Software in 1982. The players control a submarine, the Nautilus, or a destroyer, the Colossus, attempting to either destroy or rebuild an underwater city. The game the first to feature a "split screen" display to allow both players to move at the same time. Gameplay Nautilus starts with player one in control of the submarine, visible in the lower pane of the split-screen display. The joystick allows the player to move left and right or rise and sink. The player can shoot their Thunderbolt torpedoes to the right or left in the direction of travel. The primary task for the player is to move into location beside the various underwater buildings and destroy them with their torpedoes in order to expose their energy core, which can be picked up by moving over it. The player wins the level by collecting all of the cores. Player two, or the computer player in a single-player game, controls the destroyer, visible in the upper pane. The ship's primary task is to ferry repair crews from the right side of the map back to the left, dropping them into an elevator that takes them to the bottom of the ocean. From there they quickly move back towards the right through a tube on the ocean floor, instantly repairing the buildings directly above them as they pass. The destroyer also drops depth charges and Barracuda missiles that attack the submarine. The missiles track the su
https://en.wikipedia.org/wiki/Compartment
Compartment may refer to: Biology Compartment (anatomy), a space of connective tissue between muscles Compartment (chemistry), in which different parts of the same protein molecule serve different functions Compartment (development), fields of cells of distinct cell lineage, cell affinity, and genetic identity Compartment (pharmacokinetics), a defined and distinct volume of body fluids Cellular compartment, a closed part within a cell, surrounded by a membrane Other uses Compartment coach, a railway car divided into separate areas or compartments, with no means of moving between them Compartment (ship), subdivision of the space within a ship Compartment (heraldry), the part of a coat of arms design which appears immediately below the shield Multi-compartment model, a type of mathematical model "Compartments", a song and album by José Feliciano Hidden compartment See also Compartmentalization (disambiguation) Apartment Division (disambiguation) Section (disambiguation)
https://en.wikipedia.org/wiki/List%20of%20participants%20in%20the%20Evolving%20Genes%20and%20Proteins%20symposium
This is a list of scientists who participated in the 1964 Evolving Genes and Proteins symposium, a landmark event in the history of molecular evolution. The symposium, supported by the National Science Foundation, took place on September 17 and September 18, 1964 at the Institute of Microbiology of Rutgers University. A summary of the proceedings was published in Science, and the full proceedings were edited by Vernon Bryson and Henry J. Vogel and published in 1965. References Biology-related lists Evolution History of evolutionary biology
https://en.wikipedia.org/wiki/Thug%20by%20Nature
Thug by Nature is the debut solo studio album by American rapper Layzie Bone, released under his L-Burna alias. It was released on March 20, 2001 through Ruthless Records with distribution via Epic Records. Production was handled by L.T. Hutton, Darren Vegas, Michael Seifert, BB, Buddy Banks, Damon Elliott, Red Spyda, Dre' Ghost, Mauly T., Step and Thin C., with Tomica Wright and Layzie Bone serving as executive producers. It features guest appearances from Aaron Hall, Baby S, Big Chan, Dekumpozed, Flesh-n-Bone, WC and Geraldine Sigler. The album peaked at number 43 on the Billboard 200 and number 17 on the Top R&B/Hip-Hop Albums, with 36,406 copies sold in the United States in the first week. It also made it to number 30 on the Official New Zealand Music Chart. "Battlefield" and "Deadly Musical" are diss songs aimed at Chicago-based group Do Or Die. The song "Back Up Against The Wall" is featured on the Soundtrack of Down to Earth. Track listing Bonus disc Bonus disc 1 "It's all Hood Niggaz" "M.O.G." Bonus disc 2 "Money on da Wood" (featuring Bizzy Bone, Skant Bone and E-Mortal Thugs) "No Matter" Personnel Steven "Layzie Bone"/"L-Burna" Howse – main artist, executive producer Geraldine 'Gere' Sigler – vocals (track 1) William "WC" Calhoun – featured artist (track 3) Brence "Dekumpozed" Skinner – featured artist (track 5) Aaron Hall – featured artist (track 10) Stanley "Flesh-n-Bone" Howse – featured artist (track 12) "Big Chan" Gaines – featured artist (track 12) Davi
https://en.wikipedia.org/wiki/Hallandia%20antiqua%20et%20hodierna
Hallandia antiqua et hodierna is a Swedish language book on the history of Halland. It was written by Jacob Richardson and was published in two parts in 1752 and 1753; a planned third part was never published. The book is strongly influenced by Suecia antiqua et hodierna and was based on two journeys, fourteen years apart. The book mainly describes graves and remains. It does, however, also include an overview of the economy of the towns in Halland, as well as maps of towns, roads, administrative boundaries and so on. It was Richardson's opinion that Halland had gone through a golden era, in which it was more prosperous and populous. The book therefore tries to prove the existence of such a golden era, with abundant natural resources and good governance. The book lacks a conclusive overview of the political history of Halland. This is likely because of the long Danish history of the province. The book is regarded as unreliable, except for the description of the 18th century economy. See also Hallands historia och beskrifning References Halland Swedish books
https://en.wikipedia.org/wiki/Skorokhod%27s%20theorem
Skorokhod's theorem may refer to: Skorokhod's embedding theorem Skorokhod's representation theorem See also List of things named after Anatoliy Skorokhod
https://en.wikipedia.org/wiki/Abdi-Ri%C5%A1a
Abdi-Riša was a ruler-'mayor' of Enišasi, during the period of the Amarna letters correspondence (1350–1335 BC). Another mayor of Enišasi, Šatiya, is found in the Amarna letters corpus. The name "Abdi-Riša" means "servant-Riša". Abdi-Riša is only referenced in his own letter EA 363, a letter to pharaoh, (EA for 'el Amarna'). Letter no. 363 is a unique letter, being part of a letter–series, (by the same scribe): EA 174-(1), "Report on Amqu (1)" EA 175-(2), "Report on Amqu (2)" EA 176-(3), "Report on Amqu (3)" EA 363-(4), "Report on Amqu (4)" the Amqu being the "Beqaa Valley area" of Lebanon. As letter EA 363 was discovered later, (in a separate in-situ deposit), than the original letters of the Amarna letters correspondence, it is undamaged. Abdi-Riša letter EA 363, title: "A joint report on Amqu (4)" Say to the king-(i.e. Pharaoh), my lord, my god, my Sun: Message of Abdi-Riša, your servant, the ruler of E(ni)šasi. I fall in the dirt under the feet of the king, my lord, 7 times and 7 times. Look, we ar(e) in Amqu, in cities of the king, my lord, and Etakkama, the ruler of Qinsa-(Kadesh), assisted the troops of Hatti and set the cities of the king, my lord, on fire. May the king, my lord, take cognizance, and may the king, my lord, give archers that we may (re)gain the cities of the king, my lord, and dwell in the cities of the king, my lord, my god, my Sun. -EA 363, lines 1-23 (complete) The actual written name used for Enišasi in this letter is: Ešasi. See also Šatiya
https://en.wikipedia.org/wiki/Young%20rider%20classification
Young rider classification () is a cycling jersey competition in multi-day stage race events, such as the Tour de France, Giro d'Italia and many others, which awards the current leader by overall time for riders below the age of twenty-six years (or twenty-three years) depending on the race rules. At the Tour Down Under recipients are aged under twenty-six. Recipients are commonly known as the Best young rider. In stage racing, the fastest overall time of all riders below the age limit is awarded the cycling jersey, often the jersey color is white, in the same fashion the fastest time of all riders (regardless of age) is awarded in the general classification. If the best young rider is also the leader of the general classification, points classification or mountains classification, then the rider wears the most prestigious jersey and the next young rider in the classification not holding a more prestigious jersey will wear the young rider jersey. Article 2.6.018 of the UCI regulations on road cycling states: "On the basis of the classifications, only 4 leader’s jerseys of the race can be issued in events of the UCI WorldTour and continental circuits of classes HC and 1 for the men elite and under 23, and a maximum of 6 jerseys in other events. Only the leader's jersey for the individual general classification by time is compulsory. The leader of each classification, except the team classification, shall be required to wear the corresponding distinctive jersey. If a ride
https://en.wikipedia.org/wiki/Amqu
The Amqu (also Amka, Amki, Amq) is a region during the Late Bronze Age, equivalent to the Beqaa Valley region in eastern Lebanon, named in the 1350–1335 BC Amarna letters corpus. Late Bronze Amarna Archive In the Amarna letters (c. 1350 BC), two other associated regions appear to be east(?) and north(?), and are often mentioned in association with Amqu, namely Nuhašše, and Niya-Niye (or Nii). A third hypothetical region, either adjacent or within the region of Amqu, is Subaru, as according to the letter corpus possessions or people were sold: "at the land of Subaru". Initially, the northern Levant (Syria) was under the control of the Mitanni Empire. In 1350 BC, Suppiluliuma I of Hatti attacked Tushratta of Mitanni, starting a massive war in Syria, beginning with the Sack of Washukanni and ending with the Fall of Carchemish some years later. Thus, Suppiluliuma I and his generals moved on former Mitanni vassals west of the Euphrates river, causing turmoil in the region and coming in conflict with the Egyptian Empire in the southern Levant. Some lords changed their allegiance to the Hittites like Etakkama of Qidšu/Qinsa-(also Kissa)-(i.e. Kadesh). Abdi-Riša letter-(his only letter) (The scribe wrote four identical letters-(for four city-state leaders), so who the 'author' is has to be speculative.) Amarna Letter EA 363 - "A joint report on Amqu (4)" Say to the king-(i.e. Pharaoh), my lord, my god, my Sun: Message of 'Abdi-Riša, your servant, the ruler of E(ni)šasi. I fall i
https://en.wikipedia.org/wiki/Domino%20logic
Domino logic is a CMOS-based evolution of the dynamic logic techniques based on either PMOS or NMOS transistors. It allows a rail-to-rail logic swing. It was developed to speed up circuits, solving the premature cascade problem, typically by inserting small and fast pFETs between domino stages to constrain the interstage cascade velocity to a curtailed maximum—a curtailed deterministic maximum—without requiring other circuit design interlocks. Terminology The term derives from the fact that in domino logic (cascade structure consisting of several stages), each stage ripples the next stage for evaluation, similar to dominoes falling one after the other. Dynamic logic drawbacks In dynamic logic, a problem arises when cascading one gate to the next. The precharge "1" state of the first gate may cause the second gate to discharge prematurely, before the first gate has reached its correct state. This uses up the "precharge" of the second gate, which cannot be restored until the next clock cycle, so there is no recovery from this error. In order to cascade dynamic logic gates, one solution is domino logic, which inserts an ordinary static inverter between stages. While this might seem to defeat the point of dynamic logic, since the inverter has a pFET (one of the main goals of dynamic logic is to avoid pFETs where possible, due to speed), there are two reasons it works well. First, there is no fan-out to multiple pFETs; the dynamic gate connects to exactly one inverter, so t
https://en.wikipedia.org/wiki/Yidya
Yidya, and also Idiya, was the Canaanite mayor/ruler of ancient Ašqaluna in the 1350-1335 BC Amarna letters correspondence. Yidya is mainly referenced in the Amarna letters corpus, in his own letters: EA 320–326, (EA for 'el Amarna'). However, the other reference to Yidya is a letter from the pharaoh to his vassal Yidya, letter EA 370. The titles of Yidya's letters are as follows: EA 320—title: "Listening carefully (1)" EA 321—title: "Listening carefully (2)" EA 322—title: "Listening carefully (3)" EA 323—title: "A royal order for glass" EA 324—title: "Preparations completed (1)" EA 325—title: "Preparations Completed (2)" EA 326—title: "A new commissioner" The letters of Yidya EA 370, title: "From the Pharaoh to a vassal" "Say to Idiya, the ruler of Ašqaluna: Thus the king. He herewith dispatches to you this tablet-(i.e. tablet-letter), saying to you, Be on your guard. You are to guard the place of the king where you are. The king herewith sends to you Irimayašša ... ... And know that the king is hale like the Sun in the sky. For his troops and his chariots in multitude, from the Upper Land to the Lower Land, the rising of the sun to the setting of the sun, all goes very well." -EA 370, lines 1-29 (lacuna of lines 9-22) See: Amarna letters–phrases and quotations, for the phrasing: "the king is Hale like the Sun"..., for long form (like this), and short form. EA 323, title: "A royal order for glass" "To the king, my lord, my god, my Sun, the Sun from the sky: Message o
https://en.wikipedia.org/wiki/Tensor-hom%20adjunction
In mathematics, the tensor-hom adjunction is that the tensor product and hom-functor form an adjoint pair: This is made more precise below. The order of terms in the phrase "tensor-hom adjunction" reflects their relationship: tensor is the left adjoint, while hom is the right adjoint. General statement Say R and S are (possibly noncommutative) rings, and consider the right module categories (an analogous statement holds for left modules): Fix an -bimodule and define functors and as follows: Then is left adjoint to . This means there is a natural isomorphism This is actually an isomorphism of abelian groups. More precisely, if is an -bimodule and is a -bimodule, then this is an isomorphism of -bimodules. This is one of the motivating examples of the structure in a closed bicategory. Counit and unit Like all adjunctions, the tensor-hom adjunction can be described by its counit and unit natural transformations. Using the notation from the previous section, the counit has components given by evaluation: For The components of the unit are defined as follows: For in , is a right -module homomorphism given by The counit and unit equations can now be explicitly verified. For in , is given on simple tensors of by Likewise, For in , is a right -module homomorphism defined by and therefore The Ext and Tor functors The Hom functor commutes with arbitrary limits, while the tensor product functor commutes with arbitrary colimits that exist in
https://en.wikipedia.org/wiki/Raising%20and%20lowering%20indices
In mathematics and mathematical physics, raising and lowering indices are operations on tensors which change their type. Raising and lowering indices are a form of index manipulation in tensor expressions. Vectors, covectors and the metric Mathematical formulation Mathematically vectors are elements of a vector space over a field , and for use in physics is usually defined with or . Concretely, if the dimension of is finite, then, after making a choice of basis, we can view such vector spaces as or . The dual space is the space of linear functionals mapping . Concretely, in matrix notation these can be thought of as row vectors, which give a number when applied to column vectors. We denote this by , so that is a linear map . Then under a choice of basis , we can view vectors as an vector with components (vectors are taken by convention to have indices up). This picks out a choice of basis for , defined by the set of relations . For applications, raising and lowering is done using a structure known as the (pseudo-)metric tensor (the 'pseudo-' refers to the fact we allow the metric to be indefinite). Formally, this is a non-degenerate, symmetric bilinear form In this basis, it has components , and can be viewed as a symmetric matrix in with these components. The inverse metric exists due to non-degeneracy and is denoted , and as a matrix is the inverse to . Raising and lowering vectors and covectors Raising and lowering is then done in coordinates. Given
https://en.wikipedia.org/wiki/Holbein%2C%20Saskatchewan
Holbein is an organized hamlet in Saskatchewan that lies within the Rural Municipality of Shellbrook No. 493. Demographics In the 2021 Census of Population conducted by Statistics Canada, Holbein had a population of 122 living in 48 of its 54 total private dwellings, a change of from its 2016 population of 109. With a land area of , it had a population density of in 2021. References External links Holbein, Saskatchewan Community Profile Designated places in Saskatchewan Organized hamlets in Saskatchewan Shellbrook No. 493, Saskatchewan Division No. 16, Saskatchewan
https://en.wikipedia.org/wiki/Surface%20probability
In immunology, surface probability is the amount of reflection of an antigen's secondary or tertiary structure to the outside of the molecule. A greater surface probability means that an antigen is more likely to be immunogenic (i.e. induce the formation of antibodies). References Immunology
https://en.wikipedia.org/wiki/Triphenylamine
Triphenylamine is an organic compound with formula (C6H5)3N. In contrast to most amines, triphenylamine is nonbasic. At room temperature it appears as a colorless crystalline solid, with monoclinic structure. It is well miscible in diethyl ether and benzene, but it is practically insoluble in water, and partially in ethanol. Its derivatives have useful properties in electrical conductivity and electroluminescence, and they are used in OLEDs as hole-transporters. Triphenylamine can be prepared by arylation of diphenylamine. Chemical properties Triphenylamine has three aromatic groups directly linked to the central nitrogen atom. Each aromatic group acts as an electron attractor, directing the electron cloud of the lone pair of nitrogen towards it. With the delocalization of the nitrogen lone pair, a partial positive charge is conferred to nitrogen, counterbalanced by the partial negative charge localized on the aromatic groups. This arrangement prevents nitrogen protonation, a key mechanism for providing basicity to a solution. From this characteristic, moreover, it follows that the three N-C bonds all lie on the same plane and that they are located at 120° from each other, which is not the case with aliphatic amines and ammonia, where the orbitals of nitrogen are arranged in a tetrahedron. Due to steric hindrance, the phenyl groups are not on the same plane defined by the three N-C bonds, but are twisted, giving the molecule its characteristic "propeller-like" shape. See
https://en.wikipedia.org/wiki/Irimaya%C5%A1%C5%A1a
Irimayašša, or Iriyamašša was an Egyptian official, of the 1350-1335 BC Amarna letters correspondence, written from a 15-20 year time period. The 2 letters that reference him are regarding Byblos/Gubla, and Ascalon, in western and southwestern Canaan. Irimayašša is referenced in 2 letters: (EA is for 'el Amarna') EA 370–Titled: "From the Pharaoh to a vassal" –to Yidya of Ašqaluna EA 130–Titled: "Life among the 'Apiru" The 2 letters of: Official Irimayašša EA 130, by Rib-Hadda of Gubla/Byblos Title: "Life among the 'Apiru", (Sub-corpus of Rib-Hadda: no. 59 of 68). Say [t]o the king, my lord: Message of Rib-Hadda, your servant. May the Lady of Gubla grant power to the king, my lord. I fall at the feet of the king, my lord, my Sun, 7 times and 7 times. As to the king's having written to me, "Irimayašša is coming to you," ...he has not come to me. As to the king's having written to me, "Guard yourself and guard the city of the king where you are," ...who can guard me? Look, formerly my ancestors [were str]ong. There was war against the[m, but] a garrison [of the king] was wi(t)h them. There were provisions from the king at their disposal. [Though the war against me] is seve[re], I have [n]o [provision]s [from the king or gar]ri[son of the king]. Wh[at shall I] do? As for the mayors, [the]y are the ones who strik[e] our city. They are like dogs, and there is no one who wants to serve them. What am I, who live among 'Apiru, —to do? If now there are no provisions from the king fo
https://en.wikipedia.org/wiki/TIRAP
TIRAP (TIR domain containing adaptor protein) is an adapter molecule associated with toll-like receptors. The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. See also Myd88 External links
https://en.wikipedia.org/wiki/Busemann%27s%20theorem
In mathematics, Busemann's theorem is a theorem in Euclidean geometry and geometric tomography. It was first proved by Herbert Busemann in 1949 and was motivated by his theory of area in Finsler spaces. Statement of the theorem Let K be a convex body in n-dimensional Euclidean space Rn containing the origin in its interior. Let S be an (n − 2)-dimensional linear subspace of Rn. For each unit vector θ in S⊥, the orthogonal complement of S, let Sθ denote the (n − 1)-dimensional hyperplane containing θ and S. Define r(θ) to be the (n − 1)-dimensional volume of K ∩ Sθ. Let C be the curve {θr(θ)} in S⊥. Then C forms the boundary of a convex body in S⊥. See also Brunn–Minkowski inequality Prékopa–Leindler inequality References Euclidean geometry Geometric inequalities Theorems in convex geometry
https://en.wikipedia.org/wiki/Toll-like%20receptor%207
Toll-like receptor 7, also known as TLR7, is a protein that in humans is encoded by the TLR7 gene. Orthologs are found in mammals and birds. It is a member of the toll-like receptor (TLR) family and detects single stranded RNA. Function The TLR family plays an important role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on the human X chromosome. TLR7 recognizes single-stranded RNA in endosomes, which is a common feature of viral genomes which are internalised by macrophages and dendritic cells. TLR7 recognizes single-stranded RNA of viruses such as HIV and HCV. TLR7 can recognize GU-rich single-stranded RNA. However, the presence of GU-rich sequences in the single-stranded RNA is not sufficient to stimulate TLR7. Clinical significance TLR7 has been shown to play a significant role in the pathogenesis of autoimmune disorders such as lupus as well as in the regulation of antiviral immunity. Although not yet fully elucidated, using an unbiased genome-scale screen with short hairpin
https://en.wikipedia.org/wiki/Toll-like%20receptor%205
Toll-like receptor 5, also known as TLR5, is a protein which in humans is encoded by the TLR5 gene. It is a member of the toll-like receptor (TLR) family. TLR5 is known to recognize bacterial flagellin from invading mobile bacteria. It has been shown to be involved in the onset of many diseases, which includes Inflammatory bowel disease. Recent studies have also shown that malfunctioning of TLR5 is likely related to rheumatoid arthritis, osteoclastogenesis, and bone loss. Abnormal TLR5 functioning is related to the onset of gastric, cervical, endometrial and ovarian cancers. Function The TLR family plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR5 is expressed on both immune and non-immune cells. TLR5 recognizes bacterial flagellin, a principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-κB and stimulates tumor necrosis factor-alpha production. TLR5 recognizes flagellin, which is the protein monomer that makes up the filament of bacterial flagella, found on nearly all motile bacteria. There are highly conserv
https://en.wikipedia.org/wiki/Toll-like%20receptor%204
Toll-like receptor 4 is a protein that in humans is encoded by the TLR4 gene. TLR4 is a transmembrane protein, member of the toll-like receptor family, which belongs to the pattern recognition receptor (PRR) family. Its activation leads to an intracellular signaling pathway NF-κB and inflammatory cytokine production which is responsible for activating the innate immune system. TLR4 expressing cells are myeloid (erythrocytes, granulocytes, macrophages) rather than lymphoid (T-cells, B-cells, NK cells). Most myeloid cells also express high levels of CD14, which facilitates activation of TLR4 by LPS. It is most well known for recognizing lipopolysaccharide (LPS), a component present in many Gram-negative bacteria (e.g. Neisseria spp.) and selected Gram-positive bacteria. Its ligands also include several viral proteins, polysaccharide, and a variety of endogenous proteins such as low-density lipoprotein, beta-defensins, and heat shock protein. Palmitic acid and lauric acid are also TLR4 agonists, and chronic inflammatory responses via cytokine release can result from high dietary intake of these nutrients. However, unsaturated omega-3 and omega-6 fatty acids serve as TLR4 antagonists and can negate the inflammation caused by a high-fat diet. TLR4 has also been designated as CD284 (cluster of differentiation 284). The molecular weight of TLR4 is approximately 95 kDa. Function TLR4 is a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen
https://en.wikipedia.org/wiki/Period%20%28gene%29
Period (per) is a gene located on the X chromosome of Drosophila melanogaster. Oscillations in levels of both per transcript and its corresponding protein PER have a period of approximately 24 hours and together play a central role in the molecular mechanism of the Drosophila biological clock driving circadian rhythms in eclosion and locomotor activity. Mutations in the per gene can shorten (perS), lengthen (perL), and even abolish (per0) the period of the circadian rhythm. Discovery The period gene and three mutants (perS, perL, and per0) were isolated in an EMS mutagenesis screen by Ronald Konopka and Seymour Benzer in 1971. The perS, perL, and per0 mutations were found to not complement each other, so it was concluded that the three phenotypes were due to mutations in the same gene. The discovery of mutants that altered the period of circadian rhythms in eclosion and locomotor activity (perS and perL) indicated the role of the per gene in the clock itself and not an output pathway. The period gene was first sequenced in 1984 by Michael Rosbash and colleagues. In 1998, it was discovered that per produces two transcripts (differing only by the alternative splicing of a single untranslated intron) which both encode the PER protein. Function Circadian clock In Drosophila, per mRNA levels oscillate with a period of approximately 24 hours, peaking during the early subjective night. The per product PER also oscillates with a nearly 24-hour period, peaking about six hour
https://en.wikipedia.org/wiki/Vitale%27s%20random%20Brunn%E2%80%93Minkowski%20inequality
In mathematics, Vitale's random Brunn–Minkowski inequality is a theorem due to Richard Vitale that generalizes the classical Brunn–Minkowski inequality for compact subsets of n-dimensional Euclidean space Rn to random compact sets. Statement of the inequality Let X be a random compact set in Rn; that is, a Borel–measurable function from some probability space (Ω, Σ, Pr) to the space of non-empty, compact subsets of Rn equipped with the Hausdorff metric. A random vector V : Ω → Rn is called a selection of X if Pr(V ∈ X) = 1. If K is a non-empty, compact subset of Rn, let and define the set-valued expectation E[X] of X to be Note that E[X] is a subset of Rn. In this notation, Vitale's random Brunn–Minkowski inequality is that, for any random compact set X with , where "" denotes n-dimensional Lebesgue measure. Relationship to the Brunn–Minkowski inequality If X takes the values (non-empty, compact sets) K and L with probabilities 1 − λ and λ respectively, then Vitale's random Brunn–Minkowski inequality is simply the original Brunn–Minkowski inequality for compact sets. References Probabilistic inequalities Theorems in measure theory
https://en.wikipedia.org/wiki/CIITA
CIITA is a human gene which encodes a protein called the class II, major histocompatibility complex, transactivator. Mutations in this gene are responsible for the bare lymphocyte syndrome in which the immune system is severely compromised and cannot effectively fight infection. Chromosomal rearrangement of CIITA is involved in the pathogenesis of Hodgkin lymphoma and primary mediastinal B cell lymphoma. Function CIITA mRNA can only be detected in human leukocyte antigen (HLA) system class II-positive cell lines and tissues. This highly restricted tissue distribution suggests that expression of HLA class II genes is to a large extent under the control of CIITA. However, CIITA does not appear to directly bind to DNA. Instead CIITA functions through activation of the transcription factor RFX5. Hence CIITA is classified as a transcriptional coactivator. The CIITA protein contains an acidic transcriptional activation domain, 4 LRRs (leucine-rich repeats) and a GTP binding domain. The protein uses GTP binding to facilitate its own transport into the nucleus. Once in the nucleus, the protein acts as a positive regulator of class II major histocompatibility complex gene transcription, and is often referred to as the "master control factor" for the expression of these genes. CIITA expression is induced by interferon gamma, possibly assisted by other signals. MHC II expression in intestinal epithelial cells is upregulated under inflammation. Interactions CIITA has been shown
https://en.wikipedia.org/wiki/Synthetic%20genomics
Synthetic genomics is a nascent field of synthetic biology that uses aspects of genetic modification on pre-existing life forms, or artificial gene synthesis to create new DNA or entire lifeforms. Overview Synthetic genomics is unlike genetic modification in the sense that it does not use naturally occurring genes in its life forms. It may make use of custom designed base pair series, though in a more expanded and presently unrealized sense synthetic genomics could utilize genetic codes that are not composed of the two base pairs of DNA that are currently used by life. The development of synthetic genomics is related to certain recent technical abilities and technologies in the field of genetics. The ability to construct long base pair chains cheaply and accurately on a large scale has allowed researchers to perform experiments on genomes that do not exist in nature. Coupled with the developments in protein folding models and decreasing computational costs the field of synthetic genomics is beginning to enter a productive stage of vitality. History Researchers were able to create a synthetic organism for the first time in 2010. This breakthrough was undertaken by Synthetic Genomics, Inc., which continues to specialize in the research and commercialization of custom designed genomes. It was accomplished by synthesizing a 600 kbp genome (resembling that of Mycoplasma genitalium, save the insertion of a few watermarks) via the Gibson Assembly method and Transformation Associ
https://en.wikipedia.org/wiki/Rubutu
Rubutu was a city, or city-state located in ancient northern Israel, between the city of Gazru-(modern Gezer), and Jerusalem during the time of the Amarna letters correspondence, a 15-20 year period at about 1350-1335 BC. Some scholars place Rubutu near present-day Arrabah in the northern West Bank. The Amarna letters were mostly written to the pharaoh of Ancient Egypt, and three mayors of Gazru: Abimilku, Milkilu, and Yapahu authored 20 letters of the 382–letter, Amarna letters corpus. The reference to Rubutu is found in 2 letters of Abdi-Heba of Jerusalem, EA 289, and 290, (EA for 'el Amarna'). They mention the war of various cities, the Habiru, and of: "the seizure of Rubutu". The 2 letters of city--Rubutu EA 289, title: "A reckoning demanded" EA 289 is letter no. 5 of 6 to the Pharaoh, by Abdi-Heba of Jerusalem. See: Egyptian official: Pawura. EA 290, title: "Three against one" Letter no. 6 of 6 by Abdi-Heba of Urusalim: "[Sa]y [t]o the king-(i.e. pharaoh), my lord: Message of ['Abdi]-Heba, your servant. I fall at the feet [of the kin]g, my lord, 7 times and 7 times. Here is the deed against the land that Milkilu and Šuardatu did: against the land of the king, my lord, they ordered troops from Gazru, troops from Gimtu, and troops from Qiltu-(Keilah). They seized Rubutu. The land of the king deserted to the Hapiru. And now, besides this, a town belonging to Jerusalem-(called Urusalim), Bit-dNIN.URTA by name, a city of the king, has gone over to the side of the men of
https://en.wikipedia.org/wiki/Methylenedioxybutylamphetamine
Methylenedioxybutylamphetamine (MDBU or 3,4-methylenedioxy-N-butylamphetamine) is a lesser-known psychedelic drug. It is also the N-butyl derivative of 3,4-methylenedioxyamphetamine (MDA). MDBU was first synthesized by Alexander Shulgin. In his book PiHKAL, the minimum dosage is listed as 40 mg, and the duration unknown. MDBU produces few to no effects. Very little data exists about the pharmacological properties, metabolism, and toxicity of MDBU. See also Phenethylamine Psychedelics, dissociatives and deliriants MDA References Substituted amphetamines Benzodioxoles
https://en.wikipedia.org/wiki/Methylenedioxybenzylamphetamine
Methylenedioxybenzylamphetamine, abbreviated MDBZ, and systematically named 3,4-methylenedioxy-N-benzylamphetamine, is a psychedelic drug. It is the N-benzyl derivative of 3,4-methylenedioxyamphetamine (MDA). MDBZ was first synthesized by Alexander Shulgin. In his book PiHKAL (Phenethylamines i Have Known And Loved), the minimum dosage is listed as 150 mg, and the duration unknown. Very few data exist about the pharmacological properties, metabolism, and toxicity of MDBZ. In an episode of the British spoof documentary TV show Brass Eye, David Amess MP was fooled into recording a warning against a fictitious new drug called "cake". When asked a parliamentary question about it, the Home Office incorrectly assumed Amess was referring to MDBZ. Legality United Kingdom MDBZ is a Class A drug in the Drugs controlled by the UK Misuse of Drugs Act. See also Benzphetamine Benzylone Phenethylamine References External links MDBZ entry in PiHKAL MDBZ entry in PiHKAL • info Substituted amphetamines Benzodioxoles
https://en.wikipedia.org/wiki/Methylenedioxycyclopropylmethylamphetamine
MDCPM, or 3,4-methylenedioxy-N-cyclopropylmethylamphetamine, is a lesser-known psychedelic drug. It is the N-cyclopropylmethyl derivative of MDMA. MDCPM was first synthesized by Alexander Shulgin; it is also one of the compounds delineated in a patent by Horrom in 1972. In his book PiHKAL (Phenethylamines i Have Known And Loved), the minimum dosage is listed as 10 mg, and the duration unknown. MDCPM produces few to no effects. Very little data exists about the pharmacological properties, metabolism, and toxicity of MDCPM. Legality United Kingdom This substance is a Class A drug in the Drugs controlled by the UK Misuse of Drugs Act. See also Phenethylamine Psychedelics, dissociatives and deliriants MDA References External links MDCPM entry in PiHKAL MDCPM entry in PiHKAL • info Substituted amphetamines Benzodioxoles Cyclopropanes
https://en.wikipedia.org/wiki/CLEC4C
CLEC4C is a membrane protein of plasmacytoid dendritic cells used as a marker for this kind of cells and denoted as CD303 in the nomenclature of the Cluster of differentiation. References External links C-type lectins
https://en.wikipedia.org/wiki/Polynucleotide%20phosphorylase
Polynucleotide Phosphorylase (PNPase) is a bifunctional enzyme with a phosphorolytic 3' to 5' exoribonuclease activity and a 3'-terminal oligonucleotide polymerase activity. That is, it dismantles the RNA chain starting at the 3' end and working toward the 5' end. It also synthesizes long, highly heteropolymeric tails in vivo. It accounts for all of the observed residual polyadenylation in strains of Escherichia coli missing the normal polyadenylation enzyme. Discovered by Marianne Grunberg-Manago working in Severo Ochoa's lab in 1955, the RNA-polymerization activity of PNPase was initially believed to be responsible for DNA-dependent synthesis of messenger RNA, a notion that got disproved by the late 1950s. It is involved in mRNA processing and degradation in bacteria, plants, and animals. In humans, the enzyme is encoded by the gene. In its active form, the protein forms a ring structure consisting of three PNPase molecules. Each PNPase molecule consists of two RNase PH domains, an S1 RNA binding domain and a K-homology domain. The protein is present in bacteria and in the chloroplasts and mitochondria of some eukaryotic cells. In eukaryotes and archaea, a structurally and evolutionary related complex exists, called the exosome complex. The same abbreviation (PNPase) is also used for another, otherwise unrelated enzyme, Purine nucleoside phosphorylase. Model organisms Model organisms have been used in the study of PNPT1 function. A conditional knockout mouse line
https://en.wikipedia.org/wiki/Football%20records%20and%20statistics%20in%20Ukraine
Ukrainian Premier League As of the end of the 2020–21 season, unless stated otherwise. Team records Titles Most League titles: 16, Dynamo Kyiv Most consecutive League titles: 9, Dynamo Kyiv (1992–93 – 2000–01) Biggest title-winning margin: 23 points, 2019–20; Shakhtar Donetsk (82 points) over Dynamo Kyiv (59 points). Smallest title-winning margin: 0 points: 1992–93, Dynamo Kyiv and Dnipro Dnipropetrovsk both finished on 44 points, but Dynamo Kyiv won the title with a superior goal difference: (+45) over (+31); 2005–06, Shakhtar Donetsk and Dynamo Kyiv both finished on 75 points, but Shakhtar won the title by winning the golden match. Winning a title with most remaining games: 5 games, Shakhtar Donetsk (2019–20) Wins Most wins in a season: 27, Dynamo Kyiv (1999–2000) 26 games: 23, Dynamo Kyiv (2015–16) 28 games: 21, Shakhtar Donetsk (2013–14) 30 games: 27, Dynamo Kyiv (1999–2000) 32 games: 26, Shakhtar Donetsk (2019–20) 34 games: 25, Dynamo Kyiv (1994–95) Fewest wins in a season: 0, Zirka Kirovohrad (1999–2000) 26 games: 2, Nyva Ternopil (2000–01) 28 games: 2, Metalurh Zaporizhzhia and Tavriya Simferopol (2013–14) 30 games: 0, Zirka Kirovohrad (1999–2000) 32 games: 2, Karpaty Lviv (2019–20) 34 games: 4, Zorya Luhansk (1995–96) Losses Most losses in a season: 26, Zorya Luhansk (1995–96) 26 games: 21, Nyva Ternopil (2000–01) 28 games: 22, Tavriya Simferopol (2013–14) 30 games: 22, SC Mykolaiv (1998–99) 32 games: 24, Volyn Lutsk (2016–17) 34 games: 26, Zorya Luhansk (1995–
https://en.wikipedia.org/wiki/Inclusion%20%28cell%29
In cellular biology, inclusions are diverse intracellular non-living substances (ergastic substances) that are not bound by membranes. Inclusions are stored nutrients/deutoplasmic substances, secretory products, and pigment granules. Examples of inclusions are glycogen granules in the liver and muscle cells, lipid droplets in fat cells, pigment granules in certain cells of skin and hair, and crystals of various types. Cytoplasmic inclusions are an example of a biomolecular condensate arising by liquid-solid, liquid-gel or liquid-liquid phase separation. These structures were first observed by O. F. Müller in 1786. Examples Glycogen: Glycogen is the most common form of glucose in animals and is especially abundant in cells of muscles, and liver. It appears in electron micrograph as clusters, or a rosette of beta particles that resemble ribosomes, located near the smooth endoplasmic reticulum. Glycogen is an important energy source of the cell; therefore, it will be available on demand. The enzymes responsible for glycogenolysis degrade glycogen into individual molecules of glucose and can be utilized by multiple organs of the body. Lipids: Lipids are triglycerides in storage form is the common form of inclusions, not only are stored in specialized cells (adipocytes) but also are located as individuals droplets in various cell type especially hepatocytes. These are fluid at body temperature and appear in living cells as refractile spherical droplets. Lipid yields more th
https://en.wikipedia.org/wiki/Kalenderhane%20Mosque
Kalenderhane Mosque () is a former Eastern Orthodox church in Istanbul, converted into a mosque by the Ottomans. With high probability the church was originally dedicated to the Theotokos Kyriotissa. The building is sometimes referred to as Kalender Haneh Jamissi and St. Mary Diaconissa. This building represents one among the few extant examples of a Byzantine church with domed Greek cross plan. Location The mosque is located in the Fatih district of Istanbul, Turkey, in the picturesque neighborhood of Vefa, and lies immediately to the south of the easternmost extant section of the aqueduct of Valens, and less than one km to the southeast of the Vefa Kilise Mosque. History The first building on this site was a Roman bath, followed by a sixth-century (the dating was based on precise coin finds in stratigraphic excavation) hall church with an apse laying up against the Aqueduct of Valens. Later – possibly in the seventh century – a much larger church was built to the south of the first church. A third church, which reused the sanctuary and the apse (later destroyed by the Ottomans) of the second one, can be dated to the end of the twelfth century, during the late Comnenian period. It may date to between 1197 and 1204, since Constantine Stilbes alluded to its destruction in a fire in 1197. The church was surrounded by monastery buildings, which disappeared totally during the Ottoman period. After the Latin conquest of Constantinople, the building was used by the Crusaders as
https://en.wikipedia.org/wiki/Ecological%20vegetation%20class
An ecological vegetation class (EVC) is a component of the vegetation classification system developed and used by the state of Victoria, Australia, since 1994, for mapping floristic biodiversity. Ecological vegetation classes are groupings of vegetation communities based on floristic, structural, and ecological features. The Victorian Department of Environment, Land, Water and Planning has defined all of the EVCs within Victoria. An EVC consists of one or a number of floristic communities that appear to be associated with a recognisable environmental niche, and which can be characterised by a number of their adaptive responses to ecological processes that operate at the landscape scale level. Each ecological vegetation class is described through a combination of its floristic, life-form, and reproductive strategy profiles, and through an inferred fidelity to particular environmental attributes. Although there are more than 300 individual EVCs, some can be grouped together to form a bioregion, which is a geographical approach to classifying the environment using a climate, geomorphology, geology, soils and vegetation. There are 28 bioregions across Victoria. Each EVC within a biogregion can be assigned a conservation status , to indicate its degree of alteration since European settlement in Australia. To assist with the assessment of an EVC within a bioregion, benchmarks have been established to ensure that assessments are carried out in a standard fashion across Victoria.
https://en.wikipedia.org/wiki/Knudsen%20cell
In crystal growth, a Knudsen cell is an effusion evaporator source for relatively low partial pressure elementary sources (e.g. Ga, Al, Hg, As). Because it is easy to control the temperature of the evaporating material in Knudsen cells, they are commonly used in molecular-beam epitaxy. Development The Knudsen effusion cell was developed by Martin Knudsen (1871–1949). A typical Knudsen cell contains a crucible (made of pyrolytic boron nitride, quartz, tungsten or graphite), heating filaments (often made of metal tantalum), water cooling system, heat shields, and an orifice shutter. Vapor pressure measurement The Knudsen cell is used to measure the vapor pressures of a solid with very low vapor pressure. Such a solid forms a vapor at low pressure by sublimation. The vapor slowly effuses through the pinhole, and the loss of mass is proportional to the vapor pressure and can be used to determine this pressure. The heat of sublimation can also be determined by measuring the vapor pressure as a function of temperature, using the Clausius–Clapeyron relation. References Crystallography Semiconductor growth
https://en.wikipedia.org/wiki/The%20Magic%20Crystal
The Magic Crystal (; released in the Philippines as Fight to Win) is a 1986 Hong Kong action film written and directed by Wong Jing. The film stars Andy Lau, Max Mok and Cynthia Rothrock. Plot An important piece of document to be presented as evidence in court the next day against triad boss has been stolen from the Hong Kong police. Due to the time constraints, Sergeant Shek of the Special Duty Unit employs mercenary Andy Lo , known as the "Eagle Hunter", to retrieve it. Andy breaks into the triad boss's mansion where he fights his henchmen and tricks the triad boss into opening his safe where the document is hidden. Later, Andy receives a letter from his archaeologist friend, Shum Kwan, where he discovered a mysterious artifact in Greece and wants Andy to examine it with him, but also warns him to be cautious as Shum is being tailed by international spies. Andy arrives in Greece with his nephew, Ban-ban, and assistant, Snooker. While Andy was sightseeing at the Parthenon with Ban-ban and Snooker, he bumps into Shum. Shum is ambushed and chased down by KGB thugs posing as Interpol agents. Andy, along with actual agents Cindy Morgan and Billy give chase and beat up the thugs while Shum escapes. Afterwards, Cindy and her partner reveals to Andy that they know of his identity as the Eagle Hunter and informs him of Shum's situation of being hunted by the KGB and persuades him to cooperate with them to help his friend. Shum arrives at the hotel where Andy was residing but gets
https://en.wikipedia.org/wiki/Lorna%20Schultz%20Nicholson
Lorna Schultz Nicholson is a Canadian author of several children's books about sports. Raised in St. Catharines, Ontario, Nicholson obtained a B.Sc. in Human Performance from the University of Victoria. With her degree, she worked as the Fitness and Recreation Co-ordinator at the University of Victoria where she also coached rowing. Nicholson now resides in Calgary, Alberta with her husband, former Hockey Canada President Bob Nicholson. She has been an active presence in Canadian media, on television, radio and in print. Writing career Nicholson began writing as a co-host and script writer for an aerobic television show in Victoria, British Columbia. After moving to Ottawa, Ontario, she worked as a health and lifestyles reporter for a news show and researcher for a sports show, Donohue's Legends, at CJOH television. She later hosted, produced and wrote all the material for her own syndicated radio show in Ottawa, Family Time. While having shared her keen sense of sports and community in all her work, Nicholson described that only when she sat down at her computer to write fiction did she feel peace. The author of several sports novels for children, she also writes mystery novels and scripts for adults. She is currently the vice-president for the Prairie region for the Crime Writers of Canada. Nicholson is the author of the Intuko/Angie Melville adult mysteries. Bibliography Children's fiction Int. Halifax: Lorimer, 2004. Roughing . Halifax: Lorimer, 2004. Against the Boa
https://en.wikipedia.org/wiki/Serine%20dehydratase
Serine dehydratase or L-serine ammonia lyase (SDH) is in the β-family of pyridoxal phosphate-dependent (PLP) enzymes. SDH is found widely in nature, but its structure and properties vary among species. SDH is found in yeast, bacteria, and the cytoplasm of mammalian hepatocytes. SDH catalyzes the deamination of L-serine to yield pyruvate, with the release of ammonia. This enzyme has one substrate, L-serine, and two products, pyruvate and NH3, and uses one cofactor, pyridoxal phosphate (PLP). The enzyme's main role is in gluconeogenesis in the liver's cytoplasm. Nomenclature Serine Dehydratase is also known as: L-serine ammonia-lyase Serine deaminase L-hydroxyaminoacid dehydratase L-serine deaminase L-serine dehydratase L-serine hydro-lyase Structure The holoenzyme SDH contains 319 residues, one PLP cofactor molecule. The overall fold of the monomer is very similar to that of other PLP-dependent enzymes of the Beta-family. The enzyme contains a large catalytic domain that binds PLP and a small domain. The domains are linked by two residues 32-35 and 138-146, with the internal gap created being the space for the active site Cofactor Binding The PLP cofactor is positioned in between the Beta-strands 7 and 10 of the large domain and lies on the large internal gap made between small and large domain. The cofactor is covalently bonded through a Schiff base linkage to Lys41. The cofactor is sandwiched between the side chain of Phe40 and the main chain of Ala222. Each of
https://en.wikipedia.org/wiki/L-serine%20dehydratase
L-serine dehydratase may refer to: Serine dehydratase, an enzyme Threonine ammonia-lyase, an enzyme
https://en.wikipedia.org/wiki/Natural%20resistance-associated%20macrophage%20protein%202
Natural resistance-associated macrophage protein 2 (NRAMP 2), also known as divalent metal transporter 1 (DMT1) and divalent cation transporter 1 (DCT1), is a protein that in humans is encoded by the SLC11A2 (solute carrier family 11, member 2) gene. DMT1 represents a large family of orthologous metal ion transporter proteins that are highly conserved from bacteria to humans. As its name suggests, DMT1 binds a variety of divalent metals including cadmium (Cd2+), copper (Cu2+), and zinc (Zn2+,); however, it is best known for its role in transporting ferrous iron (Fe2+). DMT1 expression is regulated by body iron stores to maintain iron homeostasis. DMT1 is also important in the absorption and transport of manganese (Mn2+). In the digestive tract, it is located on the apical membrane of enterocytes, where it carries out H+-coupled transport of divalent metal cations from the intestinal lumen into the cell. Function Iron is not only essential for the human body, it is required for all organisms in order for them to be able to grow. Iron also participates in many metabolic pathways. Iron deficiency can lead to iron-deficiency anemia thus iron regulation is very crucial in the human body. In mammals The process of iron transportation consists of iron being reduced by ferrireductases that are present on the cell surface or by dietary reductants such as ascorbate (Vitamin C). Once the Fe3+ has been reduced to Fe2+, the DMT1 transporter protein transports the Fe2+ ions into the c
https://en.wikipedia.org/wiki/Admissible%20heuristic
In computer science, specifically in algorithms related to pathfinding, a heuristic function is said to be admissible if it never overestimates the cost of reaching the goal, i.e. the cost it estimates to reach the goal is not higher than the lowest possible cost from the current point in the path. It is related to the concept of consistent heuristics. While all consistent heuristics are admissible, not all admissible heuristics are consistent. Search algorithms An admissible heuristic is used to estimate the cost of reaching the goal state in an informed search algorithm. In order for a heuristic to be admissible to the search problem, the estimated cost must always be lower than or equal to the actual cost of reaching the goal state. The search algorithm uses the admissible heuristic to find an estimated optimal path to the goal state from the current node. For example, in A* search the evaluation function (where is the current node) is: where = the evaluation function. = the cost from the start node to the current node = estimated cost from current node to goal. is calculated using the heuristic function. With a non-admissible heuristic, the A* algorithm could overlook the optimal solution to a search problem due to an overestimation in . Formulation is a node is a heuristic is cost indicated by to reach a goal from is the optimal cost to reach a goal from is admissible if, Construction An admissible heuristic can be derived from a relaxed
https://en.wikipedia.org/wiki/Javier%20P%C3%A1ez
Javier Marcelo Páez (born September 23, 1975 in Merlo) is an Argentine football defender. References Javier Páez – Argentine Primera statistics at Fútbol XXI Profile and statistics of Javier Páez on One.co.il 1975 births Living people Argentine men's footballers Men's association football defenders Club Atlético Independiente footballers Deportivo Español footballers Talleres de Córdoba footballers Club Olimpo footballers S.D. Quito footballers Hapoel Tel Aviv F.C. players Atlético Tucumán footballers Chacarita Juniors footballers Argentine Primera División players Israeli Premier League players Argentine expatriate men's footballers Expatriate men's footballers in Israel Expatriate men's footballers in Ecuador Footballers from Buenos Aires Province
https://en.wikipedia.org/wiki/Coventry%20and%20Bedworth%20urban%20area
The Coventry/Bedworth Urban Area or Coventry Built-up area as defined by the Office for National Statistics had a population of 359,252 at the 2011 census, which made it the 16th largest conurbation in England and Wales by population. It is also one of the most densely populated. In the 2021 census the population of the urban area was recorded at 389,603. Details The largest settlement is Coventry (population 352,900) which is within the West Midlands County. Bedworth (population 30,648) and Binley Woods (population 2,665) are the other main parts of the conurbation and both lie in the county Warwickshire in the districts of Nuneaton and Bedworth and the Borough of Rugby respectively. There are no other towns in the conurbation. There is a very small amount of green belt between the Coventry/Bedworth Urban Area and the Nuneaton Urban Area in the north -- however with the development of industrial and retail units in south Nuneaton, the two conurbations are virtually connected -- and also between Coventry and Kenilworth. A larger area of green belt exists between Coventry and the Greater West Midlands Urban Area which extends to about 5 miles. References Urban areas of England Geography of the West Midlands (county) Coventry Geography of Warwickshire Bedworth
https://en.wikipedia.org/wiki/Tuto
Livonir Ruschel, simply known as Tuto (born 2 July 1979 in Dionísio Cerqueira) is a Brazilian professional footballer. Club statistics External links Player profile and statistics of Livonir Ruschel on One.co.il 1979 births Living people Brazilian men's footballers Brazilian expatriate men's footballers Campeonato Brasileiro Série A players Campeonato Brasileiro Série B players J1 League players J2 League players Japan Football League (1992–1998) players Israeli Premier League players Kawasaki Frontale players FC Tokyo players Urawa Red Diamonds players Shimizu S-Pulse players Omiya Ardija players Shonan Bellmare players Expatriate men's footballers in Japan Associação Atlética Ponte Preta players Associação Desportiva São Caetano players Associação Chapecoense de Futebol players Beitar Jerusalem F.C. players Expatriate men's footballers in Israel Men's association football forwards
https://en.wikipedia.org/wiki/Cristian%20Gonz%C3%A1lez%20%28footballer%2C%20born%201976%29
Cristian Mario González Aidinovich (born December 19, 1976) is an Uruguayan retired football player. External links Profile and statistics of Cristian Gonzalez on One.co.il Profile at tenfieldigital 1976 births Living people Uruguayan men's footballers Uruguay men's international footballers Uruguayan Primera División players Segunda División players Israeli Premier League players Liverpool F.C. (Montevideo) players Defensor Sporting players Peñarol players UD Las Palmas players Maccabi Tel Aviv F.C. players F.C. Ashdod players Club Atlético River Plate (Montevideo) players Beitar Jerusalem F.C. players Club Plaza Colonia de Deportes players Deportivo Maldonado players El Tanque Sisley players Sud América players Uruguayan expatriate men's footballers Expatriate men's footballers in Spain Expatriate men's footballers in Israel Uruguayan expatriate sportspeople in Spain Uruguayan expatriate sportspeople in Israel Men's association football defenders Footballers from Canelones Department
https://en.wikipedia.org/wiki/South%20End%2C%20Seattle
The South End (Soufend) is a group of neighborhoods in the southeast of Seattle, Washington, U.S.A. The definition is a bit fluid, but has traditionally included the area south of the Central District, and east of Interstate 5: Rainier Valley, Columbia City, Rainier Beach, Seward Park, Mount Baker, and Beacon Hill. Sometimes its definition is extended to Skyway and Bryn Mawr in unincorporated King County, though these are not technically in the city. Other definitions have included northern parts of Renton and Tukwila, though most Seattleites, especially those from the South End, would consider this usage incorrect. Often the term "South End" is used colloquially to include neighboring portions of South King County, by people living in those areas, due to that area's location in reference to Seattle proper. The South End has traditionally been a diverse neighborhood with a mix of Caucasian, African American, Latino and Asian communities. It is currently going through a period of redevelopment and gentrification, and was a target of former Seattle Mayor Greg Nickels's action agenda and Sound Transit's Link light rail. There is a high school sports rivalry between the South End's high schools Rainier Beach and Franklin and the Central District's Garfield. Today the neighborhood has a population of 84,180 and is 34% Asian, 27% White or Caucasian, 23% Black or African-American, 8% Hispanic and 5% other races or of mixed race. Notes External links Elizabeth Rhodes, Sitting pre
https://en.wikipedia.org/wiki/Diagnostic%20equation
In a physical (and especially geophysical) simulation context, a diagnostic equation (or diagnostic model) is an equation (or model) that links the values of these variables simultaneously, either because the equation (or model) is time-independent, or because the variables all refer to the values they have at the identical time. This is by opposition to a prognostic equation. For instance, the so-called ideal gas law (PV = nRT) of classical thermodynamics relates the state variables of that gas, all estimated at the same time. It is understood that the values of any one of these variables can change in time, but the relation between these variables will remain valid at each and every particular instant, which implies that one variable cannot change its value without the value of another variable also being affected. References James R. Holton (2004) An Introduction to Dynamic Meteorology, Academic Press, International Geophysics Series Volume 88, Fourth Edition, 535 p., , . External links Amsglossary.allenpress.com Atmospheric dynamics
https://en.wikipedia.org/wiki/Prognostic%20equation
Prognostic equation - in the context of physical (and especially geophysical) simulation, a prognostic equation predicts the value of variables for some time in the future on the basis of the values at the current or previous times. For instance, the well-known Navier-Stokes equations that describe the time evolution of a fluid are prognostic equations that predict the future distribution of velocities in that fluid on the basis of current fields such as the pressure gradient. See also diagnostic equation References James R. Holton (2004) An Introduction to Dynamic Meteorology, Academic Press, International Geophysics Series Volume 88, Fourth Edition, 535 p., , . See also http://glossary.ametsoc.org/wiki/Prognostic_equation Atmospheric dynamics
https://en.wikipedia.org/wiki/Intrinsity
Intrinsity was a privately held Austin, Texas based fabless semiconductor company; it was founded in 1997 as EVSX on the remnants of Exponential Technology and changed its name to Intrinsity in 2000. It had around 100 employees and supplied tools and services for highly efficient semiconductor logic design, enabling high performance microprocessors with fewer transistors and low power consumption. The acquisition of the firm by Apple Inc. was confirmed on April 27, 2010. Products Intrinsity's main selling point was its Fast14 technology, a set of design tools implemented in custom EDA software, for using dynamic logic and novel signal encodings to permit greater processor speeds in a given process than naive static design can offer. Concepts used in Fast14 are described in a white paper: and include the use of multi-phase clocks so that synchronisation is not required at every cycle boundary (that is, a pipelined design does not require latches at every clock cycle); 1-of-N encoding where a signal with N states is carried as a voltage on one of N wires with the other N-1 grounded, rather than being carried on log(N) wires which can be in arbitrary states; and a variety of sophisticated routing algorithms including ones which permute the order of the wires in a bundle carrying a 1-of-N signal in such a way as to reduce noise exposure, and ones which allow complicated gates to 'borrow' delay from simple ones to allow a shorter clock cycle than a more pessimistic design appro
https://en.wikipedia.org/wiki/Reversed%20electrodialysis
Reverse electrodialysis (RED) is the salinity gradient energy retrieved from the difference in the salt concentration between seawater and river water. A method of utilizing the energy produced by this process by means of a heat engine was invented by Prof. Sidney Loeb in 1977 at the Ben-Gurion University of the Negev. --United States Patent US4171409 In reverse electrodialysis a salt solution and fresh water are let through a stack of alternating cation and anion exchange membranes. The chemical potential difference between salt and fresh water generates a voltage over each membrane and the total potential of the system is the sum of the potential differences over all membranes. The process works through difference in ion concentration instead of an electric field, which has implications for the type of membrane needed. In RED, as in a fuel cell, the cells are stacked. A module with a capacity of 250 kW has the size of a shipping container. In the Netherlands, for example, more than 3,300 m3 fresh water runs into the sea per second on average. The membrane halves the pressure differences which results in a water column of approximately 135 meters. The energy potential is therefore e=mgΔh=3.3*106 kg/s*10 m/s2*135 meters ca.= 4.5*109 Joule per second, Power=4.5 gigawatts. Development In 2006 a 50 kW plant was located at a coastal test site in Harlingen, the Netherlands, the focus being on prevention of biofouling of the anode, cathode, and membranes and increasing the mem
https://en.wikipedia.org/wiki/Ifi202
Ifi202 is a mouse gene (encodes for the p202 protein). Increased expression levels of the Ifi202 mRNA and nuclear localization of p202 protein in immune cells are associated with the development of autoimmunity in certain strains of mice. Therefore, the gene has been implicated in the development of systemic lupus erythematosus (SLE). SLE is a systemic autoimmune disease responsible for attacking many types of organs. Ifi202 gene encodes for p202 protein, which belongs to the p200-protein family. The IFI family of genes is inducible by type 1 interferon and interferon gamma. The relationship between increased ifi202 expression and SLE was first suggested by Rozzo et al. in 2001. It was discovered due to the over-expression of p202 in splenic B cells of mice showing similar symptoms as lupus. Currently the prototypical mouse model for SLE is (NZWxNZB)F1, which is short for the first generation offspring of New Zealand Black and New Zealand White mice. The overproduction of p202 seems to lead to the suppression of p53 protein, which is a regulatory protein in the process of apoptosis. This is hypothesized to contribute to some of the symptoms of SLE. The p202 protein has the following structure A 52kDa nuclear phosphoprotein Humans have an ifi202 and ifi204 similar gene known as ifi16. They share some similarities in the amino acid sequence. Ifi202 is known to be regulated by IL-6. The binding of IL-6 to its receptors leads to the activation STAT3 (Signal Transducer
https://en.wikipedia.org/wiki/Propensity%20probability
The propensity theory of probability is a probability interpretation in which the probability is thought of as a physical propensity, disposition, or tendency of a given type of situation to yield an outcome of a certain kind, or to yield a long-run relative frequency of such an outcome. Propensities are not relative frequencies, but purported causes of the observed stable relative frequencies. Propensities are invoked to explain why repeating a certain kind of experiment will generate a given outcome type at a persistent rate. Stable long-run frequencies are a manifestation of invariant single-case probabilities. Frequentists are unable to take this approach, since relative frequencies do not exist for single tosses of a coin, but only for large ensembles or collectives. These single-case probabilities are known as propensities or chances. In addition to explaining the emergence of stable relative frequencies, the idea of propensity is motivated by the desire to make sense of single-case probability attributions in quantum mechanics, such as the probability of decay of a particular atom at a particular moment. History A propensity theory of probability was given by Charles Sanders Peirce. Karl Popper A later propensity theory was proposed by philosopher Karl Popper, who had only slight acquaintance with the writings of Charles S. Peirce, however. Popper noted that the outcome of a physical experiment is produced by a certain set of "generating conditions". When we
https://en.wikipedia.org/wiki/Nav1.9
{{DISPLAYTITLE:Nav1.9}} Sodium channel, voltage-gated, type XI, alpha subunit also known as SCN11A or Nav1.9 is a voltage-gated sodium ion channel protein which is encoded by the SCN11A gene on chromosome 3 in humans. Like Nav1.7 and Nav1.8, Nav1.9 plays a role in pain perception. This channel is largely expressed in small-diameter nociceptors of the dorsal root ganglion and trigeminal ganglion neurons, but is also found in intrinsic myenteric neurons. Function Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers. The 4th transmembrane segment of each domain is the voltage-sensing region of the channel. Following depolarization of the cell, voltage-gated sodium channels become inactivated through a change in conformation in which the 4th segments in each domain move into the pore region in response to the highly positive voltage expressed at the peak of the action potential. This effectively blocks the Na+ po
https://en.wikipedia.org/wiki/Earthquake%20forecasting
Earthquake forecasting is a branch of the science of seismology concerned with the probabilistic assessment of general earthquake seismic hazard, including the frequency and magnitude of damaging earthquakes in a given area over years or decades. While forecasting is usually considered to be a type of prediction, earthquake forecasting is often differentiated from earthquake prediction, whose goal is the specification of the time, location, and magnitude of future earthquakes with sufficient precision that a warning can be issued. Both forecasting and prediction of earthquakes are distinguished from earthquake warning systems, which, upon detection of an earthquake, provide a real-time warning to regions that might be affected. In the 1970s, scientists were optimistic that a practical method for predicting earthquakes would soon be found, but by the 1990s continuing failure led many to question whether it was even possible. Demonstrably successful predictions of large earthquakes have not occurred, and the few claims of success are controversial. Consequently, many scientific and government resources have been used for probabilistic seismic hazard estimates rather than prediction of individual earthquakes. Such estimates are used to establish building codes, insurance rate structures, awareness and preparedness programs, and public policy related to seismic events. In addition to regional earthquake forecasts, such seismic hazard calculations can take factors such as local g
https://en.wikipedia.org/wiki/Solar%20power%20in%20Germany
Solar power accounted for an estimated 8.2 per cent of electricity in Germany in 2019, which was almost exclusively from photovoltaics (PV). About 1.5 million photovoltaic systems were installed around the country in 2014, ranging from small rooftop systems, to medium commercial and large utility-scale solar parks. Germany's largest solar farms are located in Meuro, Neuhardenberg, and Templin with capacities over 100 MW. Germany has been among the world's top PV installer for several years, with total installed capacity amounting to 67.3 gigawatts (GW) by the end of 2022. Germany's 807 watts of solar PV per capita (2022) is the third highest in the world, behind only Australia and the Netherlands. It's estimated that by 2017 over 70% of the country's jobs in the solar industry have been lost in the solar sector in recent years. Proponents from the PV industry blame the lack of governmental commitment, while others point out the financial burden associated with the fast-paced roll-out of photovoltaics, rendering the transition to renewable energies unsustainable in their view. Germany's official governmental goal is to continuously increase renewables' contribution to the country's overall electricity consumption. Long-term targets are 80% renewable electricity by 2030 and full decarbonization before 2040. The country is increasingly producing more electricity at specific times with high solar irradiation than it needs, driving down spot-market prices and exporting its su
https://en.wikipedia.org/wiki/Philip%20Cohen%20%28British%20biochemist%29
Sir Philip Cohen (born 22 July 1945) is a British researcher, academic and Royal Medal winner based at the Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences at the University of Dundee. During the 1990s he was the world's third most cited professor (and the second most cited in the fields of biology and biochemistry) and has been described by Professor Garry Taylor of the University of St Andrews as "one of the world’s top scientists". and by Professor Sir Peter Downes as "arguably the UK's leading biochemist and an iconic figure in UK science". As of 2008 he has written over 470 peer-reviewed papers and given over 250 invited lectures in 33 countries, and has been repeatedly linked to a move of biotechnology companies to Dundee and the economic regeneration that came with it, to the point where 15% of the local economy is derived from biotech companies and their employees. His work has also seen Dundee attracting some of the world's best scientists, with over 1% of the world's most cited scientists residing in Dundee and fundraising of more than £35 million over the last 10 years to help attract them. Early life and career He was born in Middlesex, and after leaving Hendon County Grammar School he attended University College London, where he was awarded a BSc in 1966 with first class honours and a PhD in 1969 under Michael Rosemeyer. After leaving UCL he spent two years at the University of Washington doing postgraduate
https://en.wikipedia.org/wiki/3WBC
3WBC FM is a local radio station in Melbourne, Australia with a frequency of 94.1 MHz. The station is operated under licence by Whitehorse-Boroondara Community FM Radio Incorporated. It often involves local school students in its programs and is developing a larger audience. Discussion topics include current events such as global warming. Since November 2007, 3WBC has broadcast from studios in the Box Hill town hall, located in Box Hill, a suburb of Melbourne. History The Inner Eastern suburban area (that being the area comprising the then cities of Box Hill, Camberwell, Hawthorn and Kew or the cities of Boroondara and Whitehorse) was without a local radio service at the time of the formation and development of the suburban community radio groups such as SCB, ECB, VYV, MDR, etc. The Inner Eastern municipal areas lacked local service and were designated by the then ABA as a potential new area prior to licensing of the first group of Sub-Metropolitan stations offered to Southern Community Broadcasters as an addition to its licence area. Southern Community Broadcasters - after AGMs and resolutions had after an initial interest in the addition of the area to its own, had rejected the proposal - claiming the Inner East was not an area that shared the Bayside / Inner South identity. This left options open for a local community radio service to cover the Inner eastern suburbs of Melbourne When a 5-watt transmitter was first installed on top of the water tower at the corner of
https://en.wikipedia.org/wiki/The%20Girls
The Girls may be: Books The Girls (Lansens novel), a 2005 novel by Lori Lansens The Girls (Cline novel), a 2016 novel by Emma Cline The Girls, a 1921 novel by Edna Ferber Films The Girls (1961 film), a Soviet comedy film The Girls (1968 film), a Swedish drama film The Girl (1987 film), a British-Swedish drama film Music The Girls (musical), a musical based on Calendar Girls The Girls (Seattle band), Seattle punk band The Girls (1960s band), an American all-female band from the '60s "The Girls" (Calvin Harris song), 2007 "The Girls" (Blackpink song), 2023 See also Girl (disambiguation) Girls (disambiguation)
https://en.wikipedia.org/wiki/VS%20ribozyme
The Varkud satellite (VS) ribozyme is an RNA enzyme that carries out the cleavage of a phosphodiester bond. Introduction Varkud satellite (VS) ribozyme is the largest known nucleolytic ribozyme and found to be embedded in VS RNA. VS RNA is a long non-coding RNA exists as a satellite RNA and is found in mitochondria of Varkud-1C and few other strains of Neurospora. VS ribozyme contains features of both catalytic RNAs and group 1 introns. VS ribozyme has both cleavage and ligation activity and can perform both cleavage and ligation reactions efficiently in the absence of proteins. VS ribozyme undergo horizontal gene transfer with other Neurospora strains. VS ribozymes have nothing in common with other nucleolytic ribozymes. VS RNA has a unique primary, secondary, and tertiary structure. The secondary structure of the VS ribozyme consists of six helical domains (Figure 1). Stem loop I forms the substrate domain while stem-loop II-VI forms the catalytic domain. When these 2 domains are synthesized in vitro separately, they can perform the self-cleavage reaction by trans-acting The substrate binds into a cleft which is made by two helices. The likely active site of the ribozyme is a very important nucleotide A756. The A730 loop and A756 nucleotide are critical to its function since they participate in the phosphoric transfer chemistry activity of the ribozyme The Origin VS RNA is transcribed as a multimeric transcript from VS DNA. VS DNA contains a region coding reverse transcr
https://en.wikipedia.org/wiki/Pseudomonas%20boreopolis
'Pseudomonas' boreopolis is a species of Gram-negative bacteria. Following 16S rRNA phylogenetic analysis, it was determined that 'P.' boreopolis belonged in the Xanthomonas—Xylella rRNA lineage. It has not yet been further classified. References External links Type strain of Pseudomonas boreopolis at BacDive - the Bacterial Diversity Metadatabase Xanthomonadales
https://en.wikipedia.org/wiki/Football%20records%20and%20statistics%20in%20Israel
This page details football records in Israel. National team See Israel national football team records. League Records in this section refer to Palestine League from its founding in 1931 to 1947, Israeli League from 1949 to 1950, Liga Alef from 1951 to 1955, Liga Leumit from 1955 to 1999 and to the Premier League since the 1999 season. Titles Most League titles: 23, Maccabi Tel Aviv (1936, 1937, 1941–42, 1946–47, 1949–50, 1951–52, 1953–54, 1955–56, 1957–58, 1966–68, 1969–70, 1971–72, 1976–77, 1978–79, 1991–92, 1994–95, 1995–96, 2002–03, 2012–13, 2013–14, 2014–15, 2018–19, 2019–20) Most consecutive League titles: 5, Hapoel Petah Tikva (1958–59, 1959–60, 1960–61, 1961–62, 1962–63) Top-flight Appearances Most appearances: 70 seasons, Maccabi Tel Aviv (1949–present) Most consecutive seasons in top-flight: 70 seasons, Maccabi Tel Aviv (1949–present) Unbeaten runs Longest unbeaten League run: 48, Maccabi Haifa (Liga Leumit, between 3 April 1993 and 10 October 1994) Points Most points in a season: 2 points for a win: 47, Maccabi Netanya (Liga Leumit, 1970–71) 3 points for a win: 95, Maccabi Haifa (Liga Leumit, 1993–94) Fewest points in a season 2 points for a win: 0, Maccabi Nes Tziona (Israeli League, 1949–50) 3 points for a win: 10, joint record: Beitar Netanya (Liga Leumit, 1986–87) Maccabi Jaffa (Liga Leumit, 1998–99) Team Most top-flight goals scored in a season: 103, Maccabi Tel Aviv (Israeli League, 1949–50) Promotion and change in position Highest finish by a promoted
https://en.wikipedia.org/wiki/Yaak%20River
The Yaak River (spelled Yahk River in Canada) is a tributary of the Kootenai River in Montana. Course The Yaak River originates near Yahk Mountain, in the Yahk Range, part of the Purcell Mountains, in southeast British Columbia. The river flows south, crossing into Lincoln County, Montana. It receives the East Fork Yaak River, then the West Fork Yaak River (also called the West Yahk River). The West Fork originates in Montana near Rock Candy Mountain, flows northeast into British Columbia, then southeast back into Montana to join the main Yaak River. Below the West Fork confluence, the Yaak River receives the South Fork Yaak River before curving broadly west, then south, receiving numerous tributary creeks such as Spread Creek, Hellroaring Creek, and Burnt Creek (also called Burnt Grizzly Bear Creek), before flowing into the Kootenai River near Yaak Mountain and the small city of Troy, Montana. In Montana, the Yaak River and its tributaries mostly lie within Kootenai National Forest. The river has Class IV-V whitewater. The river is Class III-V from Yaak Falls to its confluence with the Kootenai River for the purposes of public access for recreational purposes. History According to British Columbia's Geographical Names Information System, "Yahk" is a Kootenai word meaning either "arrow" or "bow" and referring either to the Yaak River or the Kootenai River. The southward curve of the Kootenai River (from Canada into the United States and back into Canada) is said to be a
https://en.wikipedia.org/wiki/Thinned-array%20curse
The thinned-array curse (sometimes, sparse-array curse) is a theorem in electromagnetic theory of antennas. It states that a transmitting antenna which is synthesized from a coherent phased array of smaller antenna apertures that are spaced apart will have a smaller minimum beam spot size, but the amount of power that is beamed into this main lobe is reduced by an exactly proportional amount, so that the total power density in the beam is constant. The origin of the term is not clear. Robert L. Forward cites use of the term in unpublished Hughes Research Laboratories reports dating from 1976. Example Consider a number of small sub-apertures that are mutually adjacent to one another, so that they form a filled aperture array. Suppose that they are in orbit, beaming microwaves at a spot on the ground. Now, suppose you hold constant the number of sub-apertures and the power emitted by each, but separate the sub-apertures (while keeping them mutually phased) so as to synthesize a larger aperture. The spot size on the ground is reduced in size proportionally to the diameter of the synthesized array (and hence the area is reduced proportionally to the diameter of the synthesized array squared), but the power density at the ground is unchanged. Thus: The array is radiating the same amount of power (since each individual sub-aperture making the array radiates a constant amount of power whether or not it is adjacent the next aperture). It has the same power per unit area
https://en.wikipedia.org/wiki/FASB%20133
Launched prior to the millennium, (and subsequently amended) FAS 133 Accounting for Derivative Instruments and Hedging Activities provided an "integrated accounting framework for derivative instruments and hedging activities." FAS 133 Overview Statements of Financial Accounting Standards No. 133, Accounting for Derivative Instruments and Hedging Activities, commonly known as FAS 133, is an accounting standard issued in June 1998 by the Financial Accounting Standards Board (FASB) that requires companies to measure all assets and liabilities on their balance sheet at “fair value”. This standard was created in response to significant hedging losses involving derivatives years ago and the attempt to control and manage corporate hedging as risk management not earnings management. All derivatives within the scope of FAS133 must be recorded at fair value as an asset or liability. Hedge accounting may be applied if there is hedge documentation and gains and losses in the value of the derivative with gains and losses in the value of the underlying transaction. To be designated and qualify for FAS 133 hedge accounting, a commodity (hedged item) and its hedging instrument must have a correlation ratio between 80% and 125%, and the reporting enterprise must have hedge documentation in place at the inception of the hedge. If these criteria are not met, hedge accounting cannot be applied. The non-applicability of hedge accounting can lead to significant volatility in corporate earning
https://en.wikipedia.org/wiki/Vida%20Eterna
Vida Eterna is the first reggaeton album by Getto & Gastam and was released on November 19, 2002. The album contains 15 tracks and features the artists Tempo, Nicky Jam, Don Omar, Héctor el Father and Ivy Queen. Track listing "Intro" "Tratan" "Pégate" "Conspira" "Bailando" "Dame Tu Figura" "Ombe' No Oficial" "No Se Tiren O Se Mueren" "Interlude (Remix)" "Vengan Mujeres Al Baile" "Let's Ride" "Soy Una Persona" "My Flow" "Muchos Quieren" "Seguimos Aquí" 2002 albums Getto & Gastam albums
https://en.wikipedia.org/wiki/Janet%20Dibley
Janet Dibley (born 13 December 1958) is an English actress. She is known for her roles as Elaine Walker in the 1980s sitcom The Two of Us, Lorna Cartwright in the BBC soap opera EastEnders, and Elaine Cassidy in the BBC soap opera Doctors. Life and career Dibley was born on 13 December 1958 in Doncaster. In April 1976, before training at the Rose Bruford College, she appeared in GAS with the National Student Drama Festival, which won the Royal Shakespeare Company's inaugural Buzz Goodbody Award and The Festival Judges' Awards. Dibley came to public attention playing Elaine in ITV's The Two of Us, a sitcom about a co-habiting couple, which also featured Nicholas Lyndhurst. In 1993, Dibley played the part of Linda in The Gingerbread Girl, a series about a single mother trying to raise her daughter. She then played Lorna Cartwright in the BBC soap opera EastEnders. However, it was reported that she decided to leave the show because she was uncomfortable with the plans for her character; the script writers proposed Lorna became a prostitute and then be gang raped. Dibley agreed an exit strategy, and the plan was abandoned. The producers of Eastenders had planned to make her a central character. Dibley starred in the BBC drama The Chase, and joined the regular cast of BBC One's daytime soap opera Doctors in August 2010 playing Dr. Elaine Cassidy until September 2012. She appeared in Broadchurch in 2015, and also writes. Dibley reprised her role of Lorna Cartwright in EastEn
https://en.wikipedia.org/wiki/Integrated%20Conservation%20and%20Development%20Project
Integrated conservation and development projects (ICDPs) are biodiversity conservation projects with rural development components. This is an approach that aspires to combine social development with conservation goals(Hughes and Flintan 2001). These projects look to deal with biodiversity conservation objectives through the use of socio-economic investment tools. The World Wide Fund for Nature (WWF) first introduced ICDPs in the mid 1980s. They wanted to attend to some of the problems associated with the “fines and fences” (nonparticipatory) approach to conservation (4-Abdoulaye Ndiaye 2001). ICDPs under WWF The Wildlands & Human Needs Program was initiated in 1985 by WWF and incorporated19 ICDPs in 12 countries in Africa and South America. They wanted to improve the quality of life of rural people through projects that integrated the management of natural resources with economic development. Today there are around 300 ICDPs (1-Hughes and Flintan 2001). Various names of ICDPs ICDPs have many different names like “People-Centered Conservation and Development”, “Eco-development”, “grassroots conservation”, community-based natural resource management (CBNRM) and community wildlife management (CWM). All of which were created by the conservation organizations, rather than the indigenous people (2-Chapin 2004). Characteristics of ICDPs Biodiversity conservation is the primary goal, but ICDPs also like to deal with the social and economic requirements of communities who might
https://en.wikipedia.org/wiki/Alloy-junction%20transistor
The germanium alloy-junction transistor, or alloy transistor, was an early type of bipolar junction transistor, developed at General Electric and RCA in 1951 as an improvement over the earlier grown-junction transistor. The usual construction of an alloy-junction transistor is a germanium crystal forming the base, with emitter and collector alloy beads fused on opposite sides. Indium and antimony were commonly used to form the alloy junctions on a bar of N-type germanium. The collector junction pellet would be about 50 mils (thousandths of an inch) in diameter, and the emitter pellet about 20 mils. The base region would be on the order of 1 mil (0.001 inches, 25 μm) thick. There were several types of improved alloy-junction transistors developed over the years that they were manufactured. All types of alloy-junction transistors became obsolete in the early 1960s, with the introduction of the planar transistor which could be mass-produced easily while alloy-junction transistors had to be made individually. The first germanium planar transistors had much worse characteristics than alloy-junction germanium transistors of the period, but they cost much less, and the characteristics of planar transistors improved very rapidly, quickly exceeding those of all earlier germanium transistors. Micro-alloy transistor The micro-alloy transistor (MAT) was developed by Philco as an improved type of alloy-junction transistor, it offered much higher speed. It is constructed of a semic
https://en.wikipedia.org/wiki/Carlos%20Zarate
Carlos Zarate may refer to: Carlos Zárate Fernández (born 1980), Spanish cyclist Carlos Zárate Serna (born 1951), Mexican boxer Carlos Isagani Zarate (born 1967), Filipino lawyer, activist, and politician Carlos Serrano Zárate (born 1998), Paralympian swimmer from Colombia Carlos Zárate Jr. (born 1988), boxer from Mexico
https://en.wikipedia.org/wiki/Conglutinin
Conglutinin is a collectin protein. External links Collectins
https://en.wikipedia.org/wiki/Surfactant%20protein%20D
Surfactant protein D, also known as SP-D, is a lung surfactant protein part of the collagenous family of proteins called collectin. In humans, SP-D is encoded by the SFTPD gene and is part of the innate immune system. Each SP-D subunit is composed of an N-terminal domain, a collagenous region, a nucleating neck region, and a C-terminal lectin domain. Three of these subunits assemble to form a homotrimer, which further assemble into a tetrameric complex. Interactions Surfactant protein D has been shown to interact with DMBT1, and hemagglutinin of influenza A virus. Post-translational modification of SP-D i.e. S-nitrosylation switches its function. See also pulmonary surfactant References Further reading External links Collectins
https://en.wikipedia.org/wiki/Surfactant%20protein%20A
Surfactant protein A is an innate immune system collectin. It is water-soluble and has collagen-like domains similar to SP-D. It is part of the innate immune system and is used to opsonize bacterial cells in the alveoli marking them for phagocytosis by alveolar macrophages. SP-A may also play a role in negative feedback limiting the secretion of pulmonary surfactant. SP-A is not required for pulmonary surfactant to function but does confer immune effects to the organism. During parturition The role of surfactant protein A (SP-A) in childbirth is indicated in studies with mice. Mice which gestate for 19 days typically show signs of SP-A in amniotic fluid at around 16 days. If SP-A is injected into the uterus at 15 days, mice typically deliver early. Inversely, an SP-A inhibitor injection causes notable delays in birth. The presence of surfactant protein A seemed to trigger an inflammatory response in the uterus of the mice, but later studies found an anti-inflammatory response in humans. In fact, the level of SP-A in a human uterus typically decreases during labor. Immune functions Research on SP-A has been done mainly in rodents including mice and rats. This research has shown that mice deficient in SP-A are more susceptible to infections from group B Streptoccoal organisms, Pseudomonas aeruginosa, and likely other organisms. The immune functions of SP-A are time, temperature, and concentration dependant. Location SP-A is found in the pulmonary surfactant in lungs. SP-A a
https://en.wikipedia.org/wiki/Surfactant%20protein%20B
Surfactant protein B is an essential lipid-associated protein found in pulmonary surfactant. Without it, the lung would not be able to inflate after a deep breath out. It rearranges lipid molecules in the fluid lining the lung so that tiny air sacs in the lung, called alveoli, can more easily inflate. Gene SP-B is encoded by SFTPB, a single, 11425 nucleotide long gene on chromosome 2. Mutations in this gene are the basis for several of the lung conditions mentioned above. Both frameshift mutations and several single nucleotide polymorphisms (SNPs) have been found correlated to a variety of lung conditions. A frame shift mutation responsible for congenital alveolar proteinosis (CAP) was identified by Kattan et al. Many SNP's have been identified in relation to lung conditions. They have been correlated to severe influenza, neonatal respiratory distress syndrome, mechanical ventilation necessity, and more. Protein Surfactant protein B (SP-B) is a small protein, weighing about 8 kDa. Proteins are composed of building blocks called amino acids, and SP-B is composed of 79 of them (Valine, alanine, phenylalanine, leucine, isoleucine, and tryptophan being found in the highest levels). Nine of these carry with them a positive charge, and two carry a negative charge, leaving a protein with a net (total) charge of +7. In the body, two molecules of SP-B stick together and form what is called a homodimer. These are found embedded into membranes and other lipid structures, SP-B is
https://en.wikipedia.org/wiki/Surfactant%20protein%20C
Surfactant protein C (SP-C), is one of the pulmonary surfactant proteins. In humans this is encoded by the SFTPC gene. It is a membrane protein. Structure SFTPC is a 197-residue protein made up of two halves: a unique N-terminal propeptide domain and a C-terminal BRICHOS domain. The around 100-aa long propeptide domain actually contains not only the cleaved part, but also the mature peptide. It can be further broken down into a 23-aa helical transmembrane propeptide proper, the mature secreted SP-C (24-58), and a linker (59-89) that connects to the BRICHOS domain. The propeptide of pulmonary surfactant C has an N-terminal alpha-helical segment whose suggested function was stabilization of the protein structure, since the mature peptide can irreversibly transform from its native alpha-helical structure to beta-sheet aggregates and form amyloid fibrils. The correct intracellular trafficking of proSP-C has also been reported to depend on the propeptide. The structure of the BRICHOS domain has been solved. Mutations in this domain also lead to amyloid fibrils made up of the mature peptide, suggesting a chaperone activity. Clinical significance Mutations are associated with surfactant metabolism dysfunction type 2. Humans and animals born lacking SP-C tend to develop progressive interstitial lung disease. Recombinant SP-C is used in Venticute, an artificial lung surfactant. A process to mass-produce an analogue called rSP-C33Le by fusion with spidroin has been described.
https://en.wikipedia.org/wiki/Collectin-10
Collectin-10, also known as collectin liver 1, is a collectin protein that in humans is encoded by the COLEC10 gene. Its structure is similar to mannan-binding lectin (MBL). Collectin liver 1 (CL-L1) show very similar carbohydrate selectivity as MBL. Two other discovered collectins include collectin placenta 1 (CL-P1) and collectin kidney 1 (CL-K1). CL-L1's location found to be on chromosome 8 q23-24.1. Research concluded CL-L1 to be a serum protein. References External links Collectins
https://en.wikipedia.org/wiki/Interleukin-1%20receptor%20antagonist%20protein
The interleukin-1 receptor antagonist protein (IL-1RN) is a protein that in humans is encoded by the IL1RN gene. IL-1RN was initially called the IL-1 inhibitor and was discovered separately in 1984 by two independent laboratories. IL-1RN is an agent that binds non-productively to the cell surface interleukin-1 receptor (IL-1R), the same receptor that binds interleukin 1 family (IL-1), preventing IL-1's from sending a signal to that cell. Function IL-1RA is a member of the interleukin 1 cytokine family. IL1Ra is secreted by various types of cells including immune cells, epithelial cells, and adipocytes, and is a natural inhibitor of the pro-inflammatory effect of IL1β. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. Clinical significance A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Mutations in the IL1RN gene results in a rare disease called deficiency of the interleukin-1–receptor antagonist (DIRA). Variants of the IL1RN gene is also associated with risk of schizophrenia. Elevated levels of IL1RN has been found in serum of schizophrenia patient
https://en.wikipedia.org/wiki/IL-18
IL-18, IL 18 or IL18 may refer to: Interleukin 18, a protein encoded in humans by the IL18 gene Ilyushin Il-18, a Cold War–era Soviet airliner and military transport Illinois's 18th congressional district, a defunct U.S. House district Illinois Route 18, a rural east–west state road in central Illinois
https://en.wikipedia.org/wiki/Erna%20Braun
Erna Braun is a politician in Manitoba, Canada. She was elected to the Legislative Assembly of Manitoba in the 2007 provincial election, in the electoral division of Rossmere. Braun is a member of the New Democratic Party. She was the head of the Winnipeg Teachers Association. Electoral record References External links New Democratic Party of Manitoba MLAs Women MLAs in Manitoba Living people Year of birth missing (living people) Members of the Executive Council of Manitoba Women government ministers of Canada Politicians from Winnipeg 21st-century Canadian politicians 21st-century Canadian women politicians Canadian Mennonites Canadian Christian pacifists
https://en.wikipedia.org/wiki/1955%E2%80%9356%20Serie%20A
The 1955–56 Serie A season was won by Fiorentina. Teams Vicenza and Padova had been promoted from Serie B. Final classification Results Top goalscorers References and sources Almanacco Illustrato del Calcio - La Storia 1898-2004, Panini Edizioni, Modena, September 2005 External links - All results on RSSSF Website. Serie A seasons Italy 1955–56 in Italian football leagues
https://en.wikipedia.org/wiki/UTAC%20Group
United Test and Assembly Center Ltd (Abbreviation: UTAC; ) is one of the largest providers of test and assembly services for a wide range of semiconductor devices, including memory, mixed-signal/RF and logic integrated circuits. Founded in 1997 by Inderjit Singh and commencing full operations in 1999, the company started out by acquiring the semiconductor test operations of Fujitsu Microelectronics Asia Pte. Ltd. At the end of 2006, the company was ranked the fifth largest independent provider of semiconductor tests by Gartner Dataquest. Headquartered in Singapore, UTAC has manufacturing facilities in Singapore, Thailand, China, Indonesia and Malaysia with global sales offices located worldwide including the United States, Italy and Japan. Significant milestones In 2003, UTAC established its wholly owned Shanghai operations in Waigaoqiao - a free trade zone in Shanghai. It also formed an alliance with Amkor Technology Inc. in China, combining the strengths of both companies to create a powerful turnkey assembly and test supplier capable of supporting as well as Integrated Device Manufacturers looking to service their end customers in the China market. This partnership was further enhanced in 2007 when both companies announced that they had entered into a multi-year cross-licensing agreement under which Amkor would license its MicroLeadFrame patents to UTAC, and UTAC would license its QFN patents to Amkor. The agreement covers the license of intellectual property rights and
https://en.wikipedia.org/wiki/Book%20of%20the%20Dean%20of%20Lismore
The Book of the Dean of Lismore () is a Scottish manuscript, compiled in eastern Perthshire in the first half of the 16th century. The chief compiler, after whom it is named, was James MacGregor (Seumas MacGriogair), vicar of Fortingall and titular Dean of Lismore Cathedral, although there are other probable scribes, including his brother Donnchadh and William Drummond (Uileam Druimeanach), curate of Fortingall. It is unrelated to the similarly named Book of Lismore, an Irish manuscript from the early 15th century. The manuscript is primarily written in the "secretary hand" of Scotland, rather than the corra-litir style of hand-writing employed for written Gaelic in Ireland and Scotland. The orthography is the same kind used to write Lowland Scots, and was a common way of writing Scottish Gaelic in the Late Middle Ages. Although the principal part of the manuscript's contents are in Gaelic, the manuscript as a whole is multilingual, and there are a significant number of texts written in Scots and Latin, including extracts from the Scots poets William Dunbar (d.1530) and Robert Henryson (d.1500), and there is a great deal of Gaelic-English diglossia throughout the manuscript. Many of the Gaelic texts are of Irish provenance, and in the case of bardic poetry, Irish poems outnumber Scottish poems 44 to 21. The patrons of the manuscript appear to have been the Campbells of Glen Orchy, and the manuscript itself includes some of the poetry of Duncan Campbell (Donnchadh Caimbeul
https://en.wikipedia.org/wiki/Brown%20Lake%20%28Stradbroke%20Island%29
Brown Lake (Bummeria) is a perched lake on North Stradbroke Island, in South-East Queensland, Australia. The ecosystem is an example of a coastal non-floodplain sand lake and is characterised by acidic water, nutrient-poor and sandy soil, shrub-like vegetation and wet heathland. Brown Lake is of geographical significance, possessing ecological value. The geomorphology of the ecosystem is representative of the unique parabolic dune ridge systems that formed during the Pleistocene epoch. As a perched lake, the hydrological operations of Brown Lake are highly diverse and complex. The lake is also of cultural significance to the Aboriginal population of North Stradbroke Island, the Quandamooka people, as they possess a spiritual and physical relationship with the ecosystem. The indigenous population care for and protect the landscape, sharing traditional environmental management knowledge. Brown Lake’s cultural heritage and ecological value, along with the environmental damage associated with tourism, has led to increased conservation. The Queensland Government and the Quandamooka Yoolooburrabee Aboriginal Corporation (QYAC) have proposed an improved environmental management plan, combining traditional and contemporary management practices. Geography Brown Lake is 1 km in length and is located 4 km east of Dunwich, a small town on North Stradbroke Island. Brown Lake is in a subtropical climatic region; experiencing a wet season in the winter and a dry season in the summer. T
https://en.wikipedia.org/wiki/Amarna%20Tomb%201
Amarna Tomb 1 is a sepulchre near Amarna, Upper Egypt. It is the tomb of the ancient Egyptian noble Huya, which is located in the cluster of tombs known collectively as the Northern tombs. Huya Huya was the treasurer and steward in the house of the King's Chief Wife, Tiye and the overseer of the royal quarters of the Great King's Wife Tiye. He held further titles including that of favorite of the Lord of the Two Lands. Huya is also appointed as standard-bearer of the troop of young fighters called 'Aten Appears for him'. In other scenes, he is shown overseeing the craftsmen and others who serve under him. Mentioned in the tomb are the scribe of the House of Charm, Nakhtiu and the Overseer of the sculptors of the king's chief wife Tiye, named Iuti-Iuti. Huya also mentions his wife Wenher, and his mother Tuy. In other scenes there is mention of two possible sisters of Huya, by the name of Nebet and Kherpu(t). Decoration The tomb includes several scenes: South wall The south wall includes two scenes depicting Tiye sitting at meal with Akhenaten and Nefertiti; Akhenaten and Nefertiti are seated on the left. Akhenaten seems to wear a khat headdress and Nefertiti a short Nubian style wig. Next to Nefertiti seated on small chairs are Meritaten and one of her sisters - possibly Neferneferuaten Tasherit. Queen Tiye is shown opposite the King and Queen. She is seated and wears the double plumed headdress with the horned sundisk. She is accompanied by her daughter Baketaten, who
https://en.wikipedia.org/wiki/Nuribta
Nuribta, also Nuribda, was a city, or city-state, located in the vicinity of Magiddo in Israel, in historical Canaan during the time of the Amarna letter correspondence, a 15 to 20 year period from about 1350 to 1335 BC. The majority of the Amarna letters were written to the pharaoh of Ancient Egypt and the only reference to Naribta is a letter by Biridiya of Magidda, EA 365, entitled: "Furnishing corvée workers", (EA is for 'el Amarna'). A letter of corvée work EA 365, Biridiya letter no. 7 of 7: "Furnishing corvée workers" Say [to the ki]ng-(i.e. pharaoh), my lord and my [Su]n: Message of Biridiya, the loyal servant of the king. I fall at the feet of the king, my lord and my Sun, 7 times and 7 times. May the king, my lord, take cognizance of his servant and his city. In fact, only I am cultivating: ah-ri-šu in Šunama-(Shunem), and only I am furnishing corvée workers. But consider the mayors that are near me. They do not act as I do. They do not cultivate in Šunama, and they do not furnish corvée workers. Only I– ia8-hu-du-un-ni (by myself) furnish corvée workers. From Yapu they come, from [ my] resources here, (and) from Nuribta. And may the king, my lord, take cognizance of his city. —EA 365, lines 1-31 (complete) See also Corvée Biridiya Megiddo (place) Amarna letters–localities and their rulers Amarna letter EA 365 References Moran, William L. The Amarna Letters. Johns Hopkins University Press, 1987, 1992. (softcover, ) Amarna letters locations Canaanite cities Fo
https://en.wikipedia.org/wiki/Komarna
Komarna is a village in southern Dalmatia, Croatia, in the municipality of Slivno. It is the largest village in the municipality and located near the village of Klek. The village is south of the Neretva Delta, 70 km north of Dubrovnik on the coast of Mali Ston Bay, overlooking the Pelješac peninsula, near the Pelješac Bridge. Demographics According to the 2021 census, its population was 412. It was 167 in 2011. References External links Komarna is located in Mali Ston Bay overlooking Pelješac peninsula and small islands. Populated places in Dubrovnik-Neretva County
https://en.wikipedia.org/wiki/Collagen%2C%20type%20XVII%2C%20alpha%201
Collagen XVII, previously called BP180, is a transmembrane protein which plays a critical role in maintaining the linkage between the intracellular and the extracellular structural elements involved in epidermal adhesion, identified by Diaz and colleagues in 1990. COL17A1 is the official name of the gene. It encodes the alpha chain of type XVII collagen. Collagen XVII is a transmembrane protein, like collagen XIII, XXIII and XXV. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. It also appears to be a key protein in maintaining the integrity of the corneal epithelium. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa, as well as recurrent corneal erosions, and expression of this gene is abnormal in various cancers. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form. Structure Collagen XVII is a homotrimer of three alpha1(XVII)-chains and a transmembrane protein in type II orientation. Each 180 kD a-chain contains a globular intracellular domain of approximately 70 kDa, which interacts with beta4-integrin, plectin, and BP230 and is necessary for the stable attachment of hemidesmosomes to keratin
https://en.wikipedia.org/wiki/Improved
Improved may refer to: Improved clinch knot, a knot commonly used to secure a fishing line Improved-definition television (IDTV) Improved Touring, a category of classifications for cars in amateur road racing Improved Orion, an American research rocket LNWR Improved Precedent Class, a class of 2-4-0 steam locomotive originally designed for express passenger work See also Most Improved Player (disambiguation), a sports award Past participle of Improvement
https://en.wikipedia.org/wiki/Principal%20axis%20theorem
In geometry and linear algebra, a principal axis is a certain line in a Euclidean space associated with an ellipsoid or hyperboloid, generalizing the major and minor axes of an ellipse or hyperbola. The principal axis theorem states that the principal axes are perpendicular, and gives a constructive procedure for finding them. Mathematically, the principal axis theorem is a generalization of the method of completing the square from elementary algebra. In linear algebra and functional analysis, the principal axis theorem is a geometrical counterpart of the spectral theorem. It has applications to the statistics of principal components analysis and the singular value decomposition. In physics, the theorem is fundamental to the studies of angular momentum and birefringence. Motivation The equations in the Cartesian plane R2: define, respectively, an ellipse and a hyperbola. In each case, the x and y axes are the principal axes. This is easily seen, given that there are no cross-terms involving products xy in either expression. However, the situation is more complicated for equations like Here some method is required to determine whether this is an ellipse or a hyperbola. The basic observation is that if, by completing the square, the quadratic expression can be reduced to a sum of two squares then the equation defines an ellipse, whereas if it reduces to a difference of two squares then the equation represents a hyperbola: Thus, in our example expression, the problem
https://en.wikipedia.org/wiki/Sebastian%20Isra%C3%ABl
Sebastian Israël (, born 21 December 1977) is a former French-Israeli footballer. External links Profile and statistics of Sebastian Israël on One.co.il 1977 births Living people Israeli Jews 21st-century French Jews Israeli men's footballers French men's footballers Jewish French sportspeople Sektzia Ness Ziona F.C. players Hapoel Rishon LeZion F.C. players Hapoel Marmorek F.C. players Israeli Premier League players Jewish men's footballers Liga Leumit players French emigrants to Israel Men's association football midfielders
https://en.wikipedia.org/wiki/Bukovel
Bukovel () is the largest ski resort in Eastern Europe situated in Ukraine, in Nadvirna Raion, Ivano-Frankivsk Oblast (province) of western Ukraine. A part of it is in state property. The resort is located almost on the ridge-lines of the Carpathian Mountains at elevation of above the sea level near the village of Polianytsia (about away). It is one of the most popular ski resorts in the Ukrainian Carpathian Mountains and is situated southwest of the city of Yaremche. In 2012, Bukovel was named the fastest-growing ski resort in the world. History The resort was pioneered in 2000 by a joint venture of Scorzonera Ltd. and Horizont AL as an all-year-round tourist and recreational complex. The research for potential ski fields and cableways of the first stage was conducted in cooperation with Plan-Alp, Austria, and Ecosign, Canada, who also finalized the master plan for the resort. By late 2001, a first 691-meter ski lift was launched at the Northern slope of Mountain Bukovel along with the projected chairlift ropeway at the Bukovel's north-western slope. The project was finished in Sept.-Oct. 2002 as a 1000-metre ropeway. In 2003, a second slope, 2A ski run with a chairlift was introduced, and in 2004 a 7A ski run with a surface lift started its operation. With mere 48,000 visitors in 2003, Bukovel welcomed 206,000 tourists in 2005-2006, 400,000 in 2006-2007 and 850,000 visitors in 2008-2009. The 2010-2011 winter season recorded 1,200,000 day visits with foreigners' amounti