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https://en.wikipedia.org/wiki/Extra%20element%20theorem | The Extra Element Theorem (EET) is an analytic technique developed by R. D. Middlebrook for simplifying the process of deriving driving point and transfer functions for linear electronic circuits. Much like Thévenin's theorem, the extra element theorem breaks down one complicated problem into several simpler ones.
Driving point and transfer functions can generally be found using Kirchhoff's circuit laws. However, several complicated equations may result that offer little insight into the circuit's behavior. Using the extra element theorem, a circuit element (such as a resistor) can be removed from a circuit, and the desired driving point or transfer function is found. By removing the element that most complicate the circuit (such as an element that creates feedback), the desired function can be easier to obtain. Next, two correctional factors must be found and combined with the previously derived function to find the exact expression.
The general form of the extra element theorem is called the N-extra element theorem and allows multiple circuit elements to be removed at once.
General formulation
The (single) extra element theorem expresses any transfer function as a product of the transfer function with that element removed and a correction factor. The correction factor term consists of the impedance of the extra element and two driving point impedances seen by the extra element: The double null injection driving point impedance and the single injection driving point impe |
https://en.wikipedia.org/wiki/Niya%20Kingdom | Niya (also Niye, Niy, Nii, and Nihe) was a kingdom in Syria near the Orontes River in northern Syria next to Nuhasse.
History
Late Bronze
In the Amarna letters correspondence of 1350-1335 BC, Nii is referenced in two letters. The city of Tunip in the northern Levant had been trying to communicate to the Egyptian pharaoh for two decades, and resorted to another letter, EA 59: entitled: "From the citizens of Tunip", (EA for 'el Amarna'). The city-state of Arqa also sent a letter to pharaoh, requesting aid (EA 100).
The other letter referencing Nii concerns the individual Etakkama, his collusion with the Hittites, and the takeover of territory, 'city-states', and peoples in the northern and western Levant.
Mitanni Period
In the 15th century BC, the entire region came under the control of the Mitanni Empire.
Amarna Archive, "Nii", 2--letters
EA 59, title: "From the citizens of Tunip"
"To the king of Egypt, our lord: Message of "the citizens of Tunip", your servant. For you may all go well. And we fall at the feet of my lord.
My lord, thus says "Tunip", your servant: Tunip—who ruled it in the past? Did not Manakhpirya-(i.e. "Men-Kheper-Rê-iya"): am-ma-ti-wu-uš (your ancestor) rule it?
The gods and the ...: na-ab-ri-il-la-an (=?) of the king of Egypt, our lord, dwell in Tunip, and he should inquire of his ancients: am-ma-ti (ancient) when we did not belong to our lord, the king of Egypt-(named: Mizri).
And now, for 20–years, we have gone on writing to the king, our lord, but |
https://en.wikipedia.org/wiki/Asavari | Asavari () is a minor character from the Mahabharata, the love life of Karna but due to her father’s arrogance, the marriage did not take place. She belongs to the Asavari thaat kingdom.
In pre-Bhatkhande days this Asavari used the Komal Rishab instead of Shuddh Rishab. When Bhatkhandeji created the thaat process, he changed that Asavari's Komal Rishab to Shuddha Rishab but the name remained the same. From that time the old or real 'Asavari' has been called the Komal Rishabh Asavari, and the new Shuddha Rishabh Asavari is simply called 'Asavari'.
Raga Asavari and Komal Rishabh Asavari also appears in the Sikh tradition from northern India and is part of the Sikh holy scripture called Sri Guru Granth Sahib. Sikh Gurus Sri Guru Ramdas Ji and Sri Guru Arjun Dev Ji used these ragas. The Raga Komal Rishabh Asavari appears as 'Raga Asavari Sudhang' in Sri Guru Granth Sahib Ji.
Structure
Thaat: Asavari
Jati: Audava-Sampoorna
Arohana:
Avarohana:
Vadi:
Samavadi:
Pakad:
Time: Second period of the day (9am-12pm)
Mood: Renunciation and sacrifice
Organization and relationships
The ragas closest to Asavari are Komal Rishabh Asavari and Jaunpuri and it is part of the Kanada Raga group
Film songs
Note that the following songs are composed in Natabhairavi, the equivalent of raga Asavari in Carnatic music.
Language:Tamil
Hindi
Hume Aur Jeene Ki by Kishore Kumar and Lata Mangeshkar
Notes
References
Bor, Joep (ed). Rao, Suvarnalata; der Meer, Wim van; Harvey, Jane ( |
https://en.wikipedia.org/wiki/Graco | Graco may refer to:
Graco (baby products)
Graco (fluid handling) |
https://en.wikipedia.org/wiki/Symphony%20924 | Symphony 924 (also known as FM Stereo and Radio 5) is a 24-hour classical music radio station run by Mediacorp in Singapore. It was officially very first frequency to introduced as FM Stereo in Singapore on 18 July 1969. It is the only classical music radio station in Singapore. Symphony 924 was officially similar and related to BBC Radio 3.
History
A fifth radio station 92.4FM playing classical music was officially formal full launched. FM Stereo network begins operations was officially introducing stereo broadcast to Singapore. 92.4FM was officially launched. Singapore's first radio station to broadcast in FM Stereo since its launch with 8 hour daily broadcasts from 6:00am to 9:00am and 6:00pm to 11:00pm SST. The first broadcast was on 18 July 1969.
Until the SBC radio reforms of 1990, the station also broadcast in Mandarin, since then the station broadcasts exclusively in English.
The station converted to 24/7 broadcasts on 1 January 2008.
Tagline
Symphony's current tagline is "Only The Finest Music" and was coined in 2015. Previous taglines are include "Home Of The Arts" (till 2015) and "Classical In All Ways" (1994-2014).
Frequencies
National anthem
The National anthem plays at 06:00 SST daily at the start of the broadcasting day. The National anthem is played in full with the lyrics being sung.
Similar classical music radio
BBC Radio 3
See also
List of radio stations in Singapore
References
External links
Official Website
Radio stations in Singapore
Clas |
https://en.wikipedia.org/wiki/Polarization%20spectroscopy | Polarization spectroscopy comprises a set of spectroscopic techniques based on polarization properties of light (not necessarily visible one; UV, X-ray, infrared, or in any other frequency range of the electromagnetic radiation). By analyzing the polarization properties of light, decisions can be made about the media that emitted the light (or the media the light passes/scatters through). Alternatively, a source of polarized light may be used to probe a media; in this case, the changes in the light polarization (compared to the incidental light) allow inferences about the media's properties.
In general, any kind of anisotropy in the media results in some sort of change in polarization. Such an anisotropy can be either inherent to the media (e.g., in the case of a crystal substance), or imposed externally (e.g., in the presence of magnetic field in plasma or by another laser beam).
See also
Faraday effect
Plasma diagnostics
Stark effect
Zeeman effect
References
Spectroscopy |
https://en.wikipedia.org/wiki/Biochemical%20systems%20theory | Biochemical systems theory is a mathematical modelling framework for biochemical systems, based on ordinary differential equations (ODE), in which biochemical processes are represented using power-law expansions in the variables of the system.
This framework, which became known as Biochemical Systems Theory, has been developed since the 1960s by Michael Savageau, Eberhard Voit and others for the systems analysis of biochemical processes. According to Cornish-Bowden (2007) they "regarded this as a general theory of metabolic control, which includes both metabolic control analysis and flux-oriented theory as special cases".
Representation
The dynamics of a species is represented by a differential equation with the structure:
where Xi represents one of the nd variables of the model (metabolite concentrations, protein concentrations or levels of gene expression). j represents the nf biochemical processes affecting the dynamics of the species. On the other hand, ij (stoichiometric coefficient), j (rate constants) and fjk (kinetic orders) are two different kinds of parameters defining the dynamics of the system.
The principal difference of power-law models with respect to other ODE models used in biochemical systems is that the kinetic orders can be non-integer numbers. A kinetic order can have even negative value when inhibition is modeled. In this way, power-law models have a higher flexibility to reproduce the non-linearity of biochemical systems.
Models using power-law exp |
https://en.wikipedia.org/wiki/Mason%27s%20invariant | In electronics, Mason's invariant, named after Samuel Jefferson Mason, is a measure of the quality of transistors.
"When trying to solve a seemingly difficult problem, Sam said to concentrate on the easier ones first; the rest, including the hardest ones, will follow," recalled Andrew Viterbi, co-founder and former vice-president of Qualcomm. He had been a thesis advisee under Samuel Mason at MIT, and this was one lesson he especially remembered from his professor. A few years earlier, Mason had heeded his own advice when he defined a unilateral power gain for a linear two-port device, or U. After concentrating on easier problems with power gain in feedback amplifiers, a figure of merit for all three-terminal devices followed that is still used today as Mason's Invariant.
Origin
In 1953, transistors were only five years old, and they were the only successful solid-state three-terminal active device. They were beginning to be used for RF applications, and they were limited to VHF frequencies and below. Mason wanted to find a figure of merit to compare transistors, and this led him to discover that the unilateral power gain of a linear two-port device was an invariant figure of merit.
In his paper Power Gain in Feedback Amplifiers published in 1953, Mason stated in his introduction, "A vacuum tube, very often represented as a simple transconductance driving a passive impedance, may lead to relatively simple amplifier designs in which the input impedance (and hence the powe |
https://en.wikipedia.org/wiki/Enzyme%20activator | Enzyme activators are molecules that bind to enzymes and increase their activity. They are the opposite of enzyme inhibitors. These molecules are often involved in the allosteric regulation of enzymes in the control of metabolism. An example of an enzyme activator working in this way is fructose 2,6-bisphosphate, which activates phosphofructokinase 1 and increases the rate of glycolysis in response to the hormone glucagon. In some cases, when a substrate binds to one catalytic subunit of an enzyme, this can trigger an increase in the substrate affinity as well as catalytic activity in the enzyme's other subunits, and thus the substrate acts as an activator.
Examples
Hexokinase-I
Hexokinase-I (HK-I) is an enzyme activator because it draws glucose into the glycolysis pathway. Its function is to phosphorylate glucose releasing glucose-6-phosphate (G6P) as the product. HK-I not only signals the activation of glucose into glycolysis but also maintains a low glucose concentration to facilitate glucose diffusion into the cell. It has two catalytic domains (N-terminal domain and C-terminal domain) which are connected through an α-helix. The N-terminal acts as an allosteric regulator of C-terminal; the C-terminal is the only one involved in the catalytic activity. HK-I is regulated by the concentration of G6P, where G6P acts as a feedback inhibitor. At low G6P concentration, HK-I is activated; at high G6P concentration, the HK-I is inhibited.
Glucokinase
Glucokinase (GK) is an e |
https://en.wikipedia.org/wiki/Biodiversity%20Heritage%20Library | The Biodiversity Heritage Library (BHL) is the world’s largest open access digital library for biodiversity literature and archives. BHL operates as a worldwide consortium of natural history, botanical, research, and national libraries working together to address this challenge by digitizing the natural history literature held in their collections and making it freely available for open access as part of a global "biodiversity community". The BHL consortium works with the international taxonomic community, publishers, bioinformaticians, and information technology professionals to develop tools and services to facilitate greater access, interoperability, and reuse of content and data. BHL provides a range of services, data exports, and APIs to allow users to download content, harvest source data files, and reuse materials for research purposes. Through taxonomic intelligence tools developed by Global Names Architecture, BHL indexes the taxonomic names throughout the collection, allowing researchers to locate publications about specific taxa. In partnership with the Internet Archive and through local digitization efforts, BHL's portal provides free access to hundreds of thousands of volumes, comprising over 59 million pages, from the 15th-21st centuries.
Founded in 2006, BHL soon became the third broad digitization project for biodiversity literature, after Gallica and AnimalBase. In 2008, the size of Gallica and AnimalBase was passed, and BHL is now by far the world's largest |
https://en.wikipedia.org/wiki/Mef2 | In the field of molecular biology, myocyte enhancer factor-2 (Mef2) proteins are a family of transcription factors which through control of gene expression are important regulators of cellular differentiation and consequently play a critical role in embryonic development. In adult organisms, Mef2 proteins mediate the stress response in some tissues. Mef2 proteins contain both MADS-box and Mef2 DNA-binding domains.
Discovery
Mef2 was originally identified as a transcription factor complex through promoter analysis of the muscle creatine kinase (mck) gene to identify nuclear factors interacting with the mck enhancer region during muscle differentiation. Three human mRNA coding sequences designated RSRF (Related to Serum Response Factor) were cloned and shown to dimerize, bind a consensus sequence similar to the one present in the MCK enhancer region, and drive transcription. RSRFs were subsequently demonstrated to encode human genes now named Mef2A, Mef2B and Mef2D.
Species distribution
The Mef2 gene is widely expressed in all branches of eukaryotes from yeast to humans. While Drosophila has a single Mef2 gene, vertebrates have at least four versions of the Mef2 gene (human versions are denoted as MEF2A, MEF2B, MEF2C, and MEF2D), all expressed in distinct but overlapping patterns during embryogenesis through adulthood.
Sequence and structure
All of the mammalian Mef2 genes share approximately 50% overall amino acid identity and about 95% similarity throughout the highl |
https://en.wikipedia.org/wiki/Ammeline | Ammeline (4,6-diamino-2-hydroxy-1,3,5-triazine) is a triazine derivative. It is the hydrolysis product of melamine.
Synthesis
Ammeline can be synthesized by the pyrolysis of urea or the condensation reaction among 2 moles of dicyandiamide and 1 mole of biuret.
2 C2H4N4 + C2H5N3O2 → 2C3H5N5O + NH3
Chemical properties
Ammeline is weakly acidic with pKa ~9. It can form nitrate, sulfate, chromate, and oxalate salts. Ammeline reacts with boiling dilute hydrochloric acid to form melem and ammonia.
Ammeline is the first step in melamine hydrolysis. Further hydrolysis (e.g. boiling ammeline with dilute alkali) yields ammelide.
References
Triazines
Aromatic amines |
https://en.wikipedia.org/wiki/Commercially%20useful%20enzymes | Commercially useful enzymes (CUEs) are enzymes which have commercial uses. Microbial enzymes have well-known applications as biocatalysts in several areas of industry, such as biotechnology, agriculture, pharmaceuticals, etc. Metagenomic data provide a unique resource for discovering novel commercially useful enzymes (CUEs) from yet unidentified microbes belonging to complex microbial communities in diverse ecosystems.
Classification
A set of 510 CUEs was manually curated using publicly available information and classified into nine broad application categories based on their function. By comprehensive homology-based mining of ten diverse publicly available metagenomic data sources, several novel CUEs, homologous to those in the set of known CUEs, were identified. Using this strategy, a comprehensive Metagenomic BioMining Engine (MetaBioME) platform to facilitate homology-based computational identification of homologs for known CUEs from metagenomic datasets is developed. This is a useful resource to identify novel homologs to the existing known CUEs and to also identify new ones, both of which can be used as leads for further experimental verification.
This is available at MetaBioME.
References
Enzymes |
https://en.wikipedia.org/wiki/Major%20League%20Soccer%20records%20and%20statistics | Several Major League Soccer teams and players hold various records and statistics.
MLS Cup and Supporters' Shield winners
MLS Cup finals
Teams with most trophies
Player records (career)
Bold indicates an active player. All statistics are for regular season only.
Goals
As of the end of the 2023 regular season.
Goals from free kicks
Assists
As of the end of the 2022 regular season.
Minutes played
As of the end of the 2023 regular season.
Goals against average
As of the end of the 2020 regular season; minimum 75 matches played.
Player records (single season)
All statistics are for regular season only.
Most goals
Most assists
Most clean sheets
All-time regular season success
Supporters' Shield Standings through 2022 season.
Miami Fusion and Tampa Bay Mutiny folded after completion of the 2001 season.
Chivas USA folded after completion of the 2014 season.
All-time regular season table
Through completion of 2022 regular season.
1 – Ranking based number of points per season.
2 – Includes shoot-out wins from 1996–1999 season.
3 – Includes shoot-out losses from 1996–1999 seasons.
4 – Based on combined conference results before single format for playoff qualification was inaugurated in 2007.
All-time playoffs success
Through 2022 playoffs.
Shows number of best finishes at each playoff level through completion of 2022 playoffs. Does not include the 2020 "Play-In Round."
All-time playoffs table
Through 2020 playoffs.
1 – Ranking based on overall number |
https://en.wikipedia.org/wiki/NCAR%20LSM%201.0 | The National Center for Atmospheric Research Land Surface Model (LSM) is a unidimensional computational model developed by Gordon Bonan that describes ecological processes joined in many ecosystem models, hydrological processes found in hydrological models and flow of surface common in surface models using atmospheric models.
In this way, the model examines interactions especially biogeophysics (sensible and latent heat, momentum, albedo, emission of long waves) and biogeochemistry (CO2) of the land-atmosphere the effect of surface of the land in the climate and composition of the atmosphere.
This model has a simplified treatment of the surface flows that reproduce at the very least computational cost the essential characteristics of the important interactions of the land-atmosphere for climatic simulations.
As the types of surface vegetated for some species are several, have a standardization of types of covering being enclosed surfaces covered with water as lakes (amongst others); thus the model wheel for each point of independent form, with the same average of the atmospheric interactions. The model functions in a space grating that can vary of a point until global.
References
Bonan, G.B. (1996). A land surface model (LSM version 1.0) for ecological, hydrological, and atmospheric studies: technical description and user's guide. NCAR Technical Note NCAR/TN-417+STR. National Center for Atmospheric Research 1-150.
Bonan, G.B. (1996). Model Documentation: copy technical |
https://en.wikipedia.org/wiki/Interleaved%20polling%20with%20adaptive%20cycle%20time | Interleaved polling with adaptive cycle time (IPACT) is an algorithm designed by Glen Kramer, Biswanath Mukherjee and Gerry Pesavento of the Advanced Technology Lab at the University of California, Davis in 2002. IPACT is a dynamic bandwidth allocation algorithm for use in Ethernet passive optical networks (EPONs).
IPACT uses the Gate and Report messages provided by the EPON Multi-Point Control Protocol (MPCP) to allocate bandwidth to Optical Network Units (ONUs). If the optical line terminal grants bandwidth to an ONU and waits until it has received that particular ONU's transmission before granting bandwidth to another ONU, then time equivalent to a whole messaging round-trip is wasted during which the upstream may remain idle. IPACT eliminates this idle time by sending downstream grant messages to succeeding ONUs while receiving transmissions from previously granted ONUs. It accomplishes this by calculating the time at which a transmission grant allocated to a previous ONU ends.
References
External links
Original paper, published January 2002
Network scheduling algorithms |
https://en.wikipedia.org/wiki/Bandwidth%20guaranteed%20polling | Bandwidth Guaranteed Polling (BGP) in computing and telecommunications is a dynamic bandwidth allocation algorithm for Ethernet passive optical networks designed by Maode Ma et al. at the National University of Singapore. This is an instance of an algorithm that allocates bandwidth based on fixed weights.
BGP divides a window of time into fixed-sized slots, a number of which are allocated to each Optical Network Unit (ONU). The number allocated depends upon the ONU customer's service level agreement (SLA). If an ONU does not wish to use its entire allocated time slot, it may inform the OLT about this. The OLT may then decide to reallocate the remaining time slot to another ONU which does not have an SLA.
The BGP algorithm may not be entirely compatible with the MPCP standard. This is because the MPCP does not provide any way for the ONU to inform the OLT about the fraction of the time slot that it wishes to use.
References
M. Ma, Y. Zhu, T. H. Cheng, "Bandwidth Guaranteed Polling MAC Protocol for Ethernet Passive Optical Networks", INFOCOM 2003.
Network performance |
https://en.wikipedia.org/wiki/Drawn%20to%20Life | Drawn to Life is an action-adventure platform video game for the Nintendo DS developed by 5th Cell and published by THQ in 2007. It was later published by Agatsuma Entertainment in Japan in 2008 under the name , and in Korea under the title Geuryeora, Touch! Naega Mandeuneun Sesang. In the game, the player creates their own playable characters, level objects, and accessories by drawing them using the DS's stylus and touchscreen. The game was ported to iOS by WayForward Technologies and released by 505 Games on May 21, 2014.
Drawn to Life requires the player to create a hero in order to free a cursed village from an encroaching darkness. It features numerous platforming levels, a top-down central village, and other elements such as vehicles, weapons, and platforms, which are drawn or colored by the player using the stylus.
Two sequels followed, both under the title Drawn to Life: The Next Chapter – one released for the DS, and another released for the Wii. A spin-off title, Drawn to Life: SpongeBob SquarePants Edition (based on the SpongeBob SquarePants episode "Frankendoodle"), was developed by Altron for the DS. A third installment in the series, titled Drawn to Life: Two Realms, developed by Digital Continue and published by 505 Games, was released on December 7, 2020 for Nintendo Switch, iOS, Android, and Microsoft Windows.
Gameplay
Drawn to Life is a 2D game where the player must draw their own character, weapons and accessories, platforms, and objects. The game is se |
https://en.wikipedia.org/wiki/Conway%20base%2013%20function | The Conway base 13 function is a function created by British mathematician John H. Conway as a counterexample to the converse of the intermediate value theorem. In other words, it is a function that satisfies a particular intermediate-value property—on any interval (a, b), the function f takes every value between f(a) and f(b)—but is not continuous.
In 2018, a much simpler function with the property that every open set is mapped onto the full real line was constructed by Aksel Bergfeldt. This function is also nowhere continuous.
Purpose
The Conway base 13 function was created as part of a "produce" activity: in this case, the challenge was to produce a simple-to-understand function which takes on every real value in every interval, that is, it is an everywhere surjective function. It is thus discontinuous at every point.
Sketch of definition
Every real number x can be represented in base 13 in a unique canonical way; such representations use the digits 0–9 plus three additional symbols, say {A, B, C}. For example, the number 54349589 has a base-13 representation B34C128.
If instead of {A, B, C}, we judiciously choose the symbols {+, −, .}, something interesting happens: some numbers in base 13 will have representations that look like well-formed decimals in base 10: for example, the number 54349589 has a base-13 representation of −34.128. Of course, most numbers will not be intelligible in this way; for example, the number 3629265 has the base-13 representation 9+0−− |
https://en.wikipedia.org/wiki/Para-Nitrophenylphosphate | para-Nitrophenylphosphate (pNPP) is a non-proteinaceous chromogenic substrate for alkaline and acid phosphatases used in ELISA and conventional spectrophotometric assays. Phosphatases catalyze the hydrolysis of pNPP liberating inorganic phosphate and the conjugate base of para-nitrophenol (pNP). The resulting phenolate is yellow, with a maximal absorption at 405 nm. This property can be used to determine the activity of various phosphatases including alkaline phosphatase (AP) and protein tyrosine phosphatase (PTP).
PNPP is classified as a chromogenic substrate because of its ability to transform from a colorless compound to a colored compound through a biological mechanism, dephosphorylation. PNPP is used because of its low cost and the rate of the reactions can be measured over a wide range of substrate concentrations because the concentration of the substrate is not a limiting factor in the reaction. The limitations of PNPP is that it is a small molecule and perhaps does not entirely represent the conditions and structures that are encountered physiologically.
A PNPP assay involves mixing the sample with a PNPP-containing mixture and permitting the reaction to run its course for a predetermined period of time. After that point, the process is halted through the addition of a stop solution, often made of a potent alkali like sodium hydroxide.
The substance is sensitive to light, and thus should be stored protected from light. This is also important after adding the subst |
https://en.wikipedia.org/wiki/Bradford%20City%20Radio | Bradford City Radio or BCR as it was also known, was a small radio station in the early 1990s. It used the old Pennine Radio frequency of 103.2 FM to broadcast and was one of the Independent Broadcasting Authority's incremental stations.
Broadcasting mainly to the region's ethnic minority communities, Bradford City Radio Ltd trading as SUNRISE RADIO (Yorkshire), was formally launched on 9 December 1989 from studios based in Little Germany, just two minutes walk from Pennine Radio itself.
The frequency is now used to broadcast a local version of Sunrise Radio called Sunrise Radio (Yorkshire).
References
Defunct radio stations in the United Kingdom
Mass media in Bradford
Radio stations in Yorkshire |
https://en.wikipedia.org/wiki/Perisesarma | Perisesarma is a genus of mangrove crabs in the family Sesarmidae (or Grapsidae in some classifications) predominantly found in the Indo-Pacific. Some 23 species are described as of late 2006, with two from West Africa: P. kammermani (De Man, 1883) and P. alberti Rathbun, 1921. They are typically small, semiterrestrial crabs found on the forest floor at low tide. They eat nearly anything they can, and try to eat anything that does not threaten them — including pencils and other objects dropped on the forest floor. The last species of the genus described is P. samawati Gillikin and Schubart (2004). It can be found in East Africa along with P. guttatum, but its sister species is P. eumolpe from Malaysian mangroves.
Species
Perisesarma alberti Rathburn, 1921
Perisesarma bengalense Davie, 2003
Perisesarma bidens De Haan, 1835
Perisesarma brevicristatum Campbell, 1967
Perisesarma cricotus Rahayu and Davie, 2002
Perisesarma darwinensis Campbell, 1967
Perisesarma dussumieri H. Milne Edwar ds, 1953
Perisesarma eumolpe De Man, 1895
Perisesarma fasciatum Lanchester, 1900
Perisesarma foresti Rahayu and Davie, 2002
Perisesarma guttatum A. Milne Edwards, 1869
Perisesarma haswelli De Man, 1887
Perisesarma huzardi Desmarest, 1825
Perisesarma indiarum De Man, 1902
Perisesarma kammermani De Man, 1883
Perisesarma lanchesteri Tweedie, 1936
Perisesarma lividum A. Milne Edwards, 1869
Perisesarma longicristatum Campbell, 1967
Perisesarma maipoensis Soh, 1978
Perisesarma messa |
https://en.wikipedia.org/wiki/The%20Quiet%20Achiever | The Quiet Achiever, also known as the Holden Solar Trek, was the world's first practical long-distance solar-powered car powered entirely by photovoltaic solar cells.
The project was promoted by adventurer Hans Tholstrup, with the Australian-made car developed by Larry Perkins and his brother Garry; and sponsored by BP. In December 1982, the car, driven by Hans Tholstrup and Larry Perkins, performed the first manned transcontinental journey using only solar power, traversing Australia from west to east.
Description
The Quiet Achiever was hand-built by Larry and Garry Perkins. The body skin was made of fiberglass, while the skeleton framework was constructed of steel tubing, similar to what might be used in lightweight aircraft. The car had a large curved frontal window for the driver to see through, and side windows of clear fiberglass. The vehicle had a photovoltaic power system rated at 1 kilowatt, which powered it to an average speed of . The car's roof-mounted solar array consisted of two rows of ten 36-cell solar panels that were joined, giving a total roof area of around .
History
Development
Hans Thostrup initially had the idea of auto racing using solar energy because he was interested in conserving non-renewable resources. He and Larry Perkins were inspired by the Sunmobile, a solar-powered miniature car built by General Motors which was publicly demonstrated in Chicago, United States, in 1955. BP sponsored the Quiet Achiever project, which was labelled the BP S |
https://en.wikipedia.org/wiki/Kuijken | Kuijken (meaning "the hatched young of a bird, especially fowl"; modern Dutch spelling kuiken) is a Dutch surname. The name comes from the city of Cuijk, it is a derivative of the Celtic word Keujka with the meaning of a river meander. It may refer to:
A Belgian family of musicians
Barthold Kuijken – baroque flute player
Sigiswald Kuijken – conductor and baroque violin player
Wieland Kuijken – viol and cello player
Marleen Kuijken-Thiers – viola player; wife of Sigiswald Kuijken
Marie Kuijken – soprano and fortepianist; stage director. Daughter of Sigiswald
Sara Kuijken – baroque violinist. Daughter of Sigiswald
Veronica Kuijken – violinist and pianist. Daughter of Sigiswald
Filip Kuijken – luthier in Japan
Ivar Kuijken (b. 1987) – woodwind player. Son of Barthold
Piet Kuijken (b. 1972) – fortepiano player. Son of Wieland
See also
Susan Kuijken (born 1986), Dutch distance runner
Friedrich Wilhelm Kücken (Low German form)
Andreas Kück, German keyboardist
Dutch words and phrases
Archaic words and phrases
Dutch-language surnames |
https://en.wikipedia.org/wiki/HLA-DM | HLA-DM (human leukocyte antigen DM) is an intracellular protein involved in the mechanism of antigen presentation on antigen presenting cells (APCs) of the immune system. It does this by assisting in peptide loading of major histocompatibility complex (MHC) class II membrane-bound proteins. HLA-DM is encoded by the genes HLA-DMA and HLA-DMB.
HLA-DM is a molecular chaperone that works in lysosomes and endosomes in cells of the immune system. It works in APCs like macrophages, dendritic cells, and B cells by interacting with MHC class II molecules. HLA-DM protects the MHC class II molecules from breaking down, and regulates which proteins or peptides bind to them as well. This regulates how and when a peptide acts as an antigen initiating an immune response. Thus, HLA-DM is necessary for the immune system to respond effectively to a foreign invader. Impairment in HLA-DM function can result in immunodeficiency and autoimmune diseases.
Genetics
The genes for HLA-DM are located in the MHCII region of the human chromosome 6. The genes code for the alpha and beta chains that make up the protein.
The gene is nonpolymorphic.
Function
MHC class II + peptide interactions
HLA-DM is an integral protein in the mechanism regulating which antigens are presented extracellularly on APCs. It binds partially to the peptide-binding groove of MHC class II molecules. This can affect how well your immune system responds to foreign invaders.
HLA-DM is required to release CLIP from MHC class |
https://en.wikipedia.org/wiki/J%20chain | The Joining (J) chain is a protein component that links monomers of antibodies IgM and IgA to form polymeric antibodies capable of secretion. The J chain is well conserved in the animal kingdom, but its specific functions are yet to be fully understood. It is a 137 residue polypeptide, encoded by the IGJ gene.
Structure
The J chain is a glycoprotein of molecular weight 15 kDa. Its secondary structure remains undetermined but is believed to adopt either a single β-barrel or two-domain folded structure with standard immunoglobulin domains. The J chain's primary structure is unusually acidic having a high content of negatively charged amino acids. It has 8 cysteine residues, 6 of which are involved in intramolecular disulfide bonds while the remaining two function to bind the Fc tailpiece regions of IgA or IgM antibodies, the α chain and μ chain respectively. An N-linked carbohydrate resulting from N-glycosylation is also essential in the protein's incorporation to antibody polymers. There is no known protein family with significant homology to the J chain.
Function
Antibody polymerization
The J chain regulates the multimerization of IgM and IgA in mammals. When expressed in cells, it favors the formation of a pentameric IgM and an IgA dimer. IgM pentamers are most commonly found with a single J chain, but some studies have seen as many as 4 J chains associated to a single IgM pentamer.
The J chain is incorporated late in the formation of IgM polymers and thermodynamic |
https://en.wikipedia.org/wiki/Manifest%20expression | A manifest expression is a programming language construct that a compiler can analyse to deduce which values it can take without having to execute the program. This information can enable compiler optimizations, in particular loop nest optimization, and parallelization through data dependency analysis. An expression is called manifest if it is computed only from outer loop counters and constants (a more formal definition is given below).
When all control flow for a loop or condition is regulated by manifest expressions, it is called a manifest loop resp. condition.
Most practical applications of manifest expressions also require the expression to be integral and affine (or stepwise affine) in its variables.
Definition
A manifest expression is a compile time computable function which depends only on
compile-time constants,
manifest variable references, and
loop counters of loops surrounding the expression.
A manifest variable reference is itself defined as a variable reference with
a single, unambiguous definition of its value,
which is itself a manifest expression.
The single, unambiguous definition is particularly relevant in procedural languages, where pointer analysis and/or data flow analysis is required to find the expression that defines the variable value. If several defining expressions are possible (e.g. because the variable is assigned in a condition), the variable reference is not manifest.
See also
Polytope model which requires manifest loops and |
https://en.wikipedia.org/wiki/Polymeric%20immunoglobulin%20receptor | Polymeric immunoglobulin receptor (pIgR) is a transmembrane protein that in humans is encoded by the PIGR gene. It is an Fc receptor which facilitates the transcytosis of the soluble polymeric isoforms of immunoglobulin A and immunoglobulin M (pIg) and immune complexes. pIgRs are mainly located on the epithelial lining of mucosal surfaces of the gastrointestinal tract. The composition of the receptor is complex, including 6 immunoglobulin-like domains, a transmembrane region, and an intracellular domain. pIgR expression is under the strong regulation of cytokines, hormones, and pathogenic stimuli.
Structure
pIgR is produced among others by intestinal epithelial cells (IECs) and bronchial epithelial cells. pIgR belongs to the family of type I transmembrane proteins. The extracellular portion of the protein contains 6 domains: 5 evolutionary conserved immunoglobulin-like domains, and 1 non-homologous domain, which is involved in proteolytic cleavage of pIg-pIgR complex from the apical side of the IECs. The quite long intracellular domain of the receptor, along with the transmembrane region, is responsible for the transduction of highly conserved signals. During transcytosis, an essential part of pIgR, the secretory component, is attached to the ligand and later cleaved with the ligand to form fully functioning secreted IgA.
History
Per Brandtzaeg showed that secretory component acts as a plasma membrane receptor on epithelial cells for polymeric immunoglobulin A and immuno |
https://en.wikipedia.org/wiki/TCF7L2 | Transcription factor 7-like 2 (T-cell specific, HMG-box), also known as TCF7L2 or TCF4, is a protein acting as a transcription factor that, in humans, is encoded by the TCF7L2 gene. The TCF7L2 gene is located on chromosome 10q25.2–q25.3, contains 19 exons. As a member of the TCF family, TCF7L2 can form a bipartite transcription factor and influence several biological pathways, including the Wnt signalling pathway.
Single-nucleotide polymorphisms (SNPs) in this gene are especially known to be linked to higher risk to develop type 2 diabetes, gestational diabetes, multiple neurodevelopmental disorders including schizophrenia and autism spectrum disorder, as well as other diseases. The SNP rs7903146, within the TCF7L2 gene, is, to date, the most significant genetic marker associated with type 2 diabetes risk.
Function
TCF7L2 is a transcription factor influencing the transcription of several genes thereby exerting a large variety of functions within the cell. It is a member of the TCF family that can form a bipartite transcription factor (β-catenin/TCF) alongside β-catenin. Bipartite transcription factors can have large effects on the Wnt signalling pathway. Stimulation of the Wnt signaling pathway leads to the association of β-catenin with BCL9, translocation to the nucleus, and association with TCF7L2, which in turn results in the activation of Wnt target genes. The activation of the Wnt target genes specifically represses proglucagon synthesis in enteroendocrine cells. The |
https://en.wikipedia.org/wiki/Price%20optimization | Price optimization is the use of mathematical analysis by a company to determine how customers will respond to different prices for its products and services through different channels. It is also used to determine the prices that the company determines will best meet its objectives such as maximizing operating profit. The data used in price optimization can include survey data, operating costs, inventories, and historic prices & sales. Price optimization practice has been implemented in industries including retail, banking, airlines, casinos, hotels, car rental, cruise lines and insurance industries.
Overview
Price optimization utilizes data analysis to predict the behavior of potential buyers to different prices of a product or service. Depending on the type of methodology being implemented, the analysis may leverage survey data (e.g. such as in a conjoint pricing analysis) or raw data (e.g. such as in a behavioral analysis leveraging 'big data' ). Companies use price optimization models to determine pricing structures for initial pricing, promotional pricing and discount pricing.
Market simulators are often used to simulate the choices people make to predict how demand varies at different price points. This data can be combined with cost and inventory levels to develop a profitable price point for that product or service. This model is also used to evaluate pricing for different customer segments by simulating how targeted customers will respond to price changes with dat |
https://en.wikipedia.org/wiki/Cobalt%28II%29%20naphthenate | Cobalt(II) naphthenate is a mixture of cobalt(II) derivatives of naphthenic acids. These coordination complexes are widely used as oil drying agents for the autoxidative crosslinking of drying oils. Metal naphthenates are not well defined in conventional chemical sense that they are mixtures. They are widely employed catalysts because they are soluble in the nonpolar substrates, such as the alkyd resins or linseed oil. The fact that naphthenates are mixtures helps to confer high solubility. A second virtue of these species is their low cost. A well-defined compound that exhibits many of the properties of cobalt naphthenate is the cobalt(II) complex of 2-ethylhexanoic acid. Often in technical literature, naphthenates are described as salts, but they are probably also non-ionic coordination complexes with structures similar to basic zinc acetate.
The catalytic properties of cobalt(II) naphthenates are similar to those of related compounds containing manganese and iron. Such species are sometimes classified as active driers. Active driers are catalysts that feature redox-active metal centers. Such centers promote redox reactions with hydroperoxide-containing intermediates.
Toxicity and safety
Cobalt Naphthenate is a moderately toxic substance which can cause a range of acute and chronic conditions, and it is also a carcinogen. It is most commonly used diluted in mineral spirit or mineral oil. Safety equipment must be used to avoid eye and skin contact. The pure compound h |
https://en.wikipedia.org/wiki/TCF4 | Transcription factor 4 (TCF-4) also known as immunoglobulin transcription factor 2 (ITF-2) is a protein that in humans is encoded by the TCF4 gene located on chromosome 18q21.2.
Function
TCF4 proteins act as transcription factors which will bind to the immunoglobulin enhancer mu-E5/kappa-E2 motif. TCF4 activates transcription by binding to the E-box (5’-CANNTG-3’) found usually on SSTR2-INR, or somatostatin receptor 2 initiator element. TCF4 is primarily involved in neurological development of the fetus during pregnancy by initiating neural differentiation by binding to DNA. It is found in the central nervous system, somites, and gonadal ridge during early development. Later in development it will be found in the thyroid, thymus, and kidneys while in adulthood TCF4 it is found in lymphocytes, muscles, mature neurons, and gastrointestinal system.
Clinical significance
Mutations in TCF4 cause Pitt-Hopkins Syndrome (PTHS). These mutations cause TCF4 proteins to not bind to DNA properly and control the differentiation of the nervous system. It has been suggested that TCF4 loss-of-function leads to decreased Wnt signaling and, consequently, a reduced neural progenitor proliferation. In most cases that have been studied, the mutations were de novo, meaning it was a new mutation not found in other family members of the patient. Common symptoms of Pitt-Hopkins Syndrome include a wide mouth, gastrointestinal problems, developmental delay of fine motor skills, speech and breathi |
https://en.wikipedia.org/wiki/Johannes%20Martin%20Bijvoet | Johannes Martin Bijvoet (23 January 1892, Amsterdam – 4 March 1980, Winterswijk) was a Dutch chemist and crystallographer at the van 't Hoff Laboratory at Utrecht University. He is famous for devising a method of establishing the absolute configuration of molecules. In 1946, he became member of the Royal Netherlands Academy of Arts and Sciences.
The concept of tetrahedrally bound carbon in organic compounds stems back to the work by van 't Hoff and Le Bel in 1874. At this time, it was impossible to assign the absolute configuration of a molecule by means other than referring to the projection formula established by Fischer, who had used glyceraldehyde as the prototype and assigned randomly its absolute configuration.
In 1949 Bijvoet outlined his principle, which relies on the anomalous dispersion of X-ray radiation. Instead of the normally observed elastic scattering of X-rays when they hit an atom, which generates a scattered wave of the same energy but with a shift in phase, X-ray radiation near the absorption edge of an atom creates a partial ionisation process. Some new X-ray radiation is generated from the inner electron shells of the atoms. The X-ray radiation already being scattered is interfered with by the new radiation, both amplitude and phase being altered. These additional contributions to the scattering may be written as a real part f''' and an imaginary one, f". Whereas the real part is either positive or negative, the imaginary is always positive, resulting |
https://en.wikipedia.org/wiki/Commodity%20cell | A commodity cell is a type of battery made in large volumes for use by original equipment manufacturers. For example, commodity cells are used in laptops and cell phones, as the energy storage element in its batteries.
Production
The auto industry battery consortium, USABC, set about to invent automotive batteries made from specialty cells for cars.
Tesla Motors uses commodity cells to make their automotive batteries.
Practically all commodity cells today are made in Asia – mainly Japan, South Korea, and China. There is no significant production anywhere in the US. A modern lithium ion cell plant – such as those in Japan – is a highly automated affair with very low labor content.
See also
List of battery types
References
http://www.finance.senate.gov/imo/media/doc/050107testme.pdf
External links
Tesla Motors
http://www.finance.senate.gov/imo/media/doc/050107testme.pdf
Battery applications |
https://en.wikipedia.org/wiki/Hepatocyte%20nuclear%20factors | Hepatocyte nuclear factors (HNFs) are a group of phylogenetically unrelated transcription factors that regulate the transcription of a diverse group of genes into proteins. These proteins include blood clotting factors and in addition, enzymes and transporters involved with glucose, cholesterol, and fatty acid transport and metabolism.
Function
As the name suggests, hepatocyte nuclear factors are expressed predominantly in the liver. However HNFs are also expressed and play important roles in a number of other tissues so that the name hepatocyte nuclear factor is somewhat misleading. Nevertheless, the liver is the only tissue in which a significant number of different HNFs are expressed at the same time. In addition, there are a number of genes which contain multiple promoter and enhancer regions each regulated by a different HNF. Furthermore, efficient expression of these genes require synergistic activation by multiple HNFs. Hence hepatocyte nuclear factors function to ensure liver specific expression of certain genes.
As is the case with many transcription factors, HNFs regulate the expression of a wide variety of target genes and therefore functions. These functions (and especially functions involving the liver) include development and metabolic homeostasis of the organism. For example, HNFs influence expression of the insulin gene as well as genes involved in glucose transport and metabolism. In embryo development, HNF4α is thought to have an important role |
https://en.wikipedia.org/wiki/Rho%20family%20of%20GTPases | The Rho family of GTPases is a family of small (~21 kDa) signaling G proteins, and is a subfamily of the Ras superfamily. The members of the Rho GTPase family have been shown to regulate many aspects of intracellular actin dynamics, and are found in all eukaryotic kingdoms, including yeasts and some plants. Three members of the family have been studied in detail: Cdc42, Rac1, and RhoA. All G proteins are "molecular switches", and Rho proteins play a role in organelle development, cytoskeletal dynamics, cell movement, and other common cellular functions.
History
Identification of the Rho family of GTPases began in the mid-1980s. The first identified Rho member was RhoA, isolated serendipitously in 1985 from a low stringency cDNA screening. Rac1 and Rac2 were identified next, in 1989 followed by Cdc42 in 1990. Eight additional mammalian Rho members were identified from biological screenings until the late 1990s, a turning point in biology where availability of complete genome sequences allowed full identification of gene families. All eukaryote cells contain Rho GTPase (ranging from 6 in yeast to 20 in mammals). In mammals, the Rho family is thus made of 20 members distributed in 8 subfamilies: Rho, Rnd, RhoD/F, RhoH, Rac, Cdc42, RhoU/V and RhoBTB.
As early as 1990, Paterson et al. began expressing activated Rho protein in Swiss 3T3 fibroblasts.
By the mid-1990s, Rho proteins had been observed to affect the formation of cellular projections ("processes") in fibroblasts. In a |
https://en.wikipedia.org/wiki/Complement%20deficiency | Complement deficiency is an immunodeficiency of absent or suboptimal functioning of one of the complement system proteins. Because of redundancies in the immune system, many complement disorders are never diagnosed. Some studies estimate that less than 10% are identified. Hypocomplementemia may be used more generally to refer to decreased complement levels, while secondary complement disorder means decreased complement levels that are not directly due to a genetic cause but secondary to another medical condition.
Signs and symptoms
The following symptoms (signs) are consistent with complement deficiency in general:
Complications
Vaccinations for encapsulated organisms (e.g., Neisseria meningitidis and Streptococcus pneumoniae) is crucial for preventing infections in complement deficiencies. Among the possible complications are the following:
Deficiencies of the terminal complement components increases susceptibility to infections by Neisseria.
Causes
The cause of complement deficiency is genetics (though cases of an acquired nature do exist post infection). The majority of complement deficiencies are inherited as autosomal recessive conditions, while properdin deficiency occurs through X-linked inheritance. MBL deficiency can be inherited by either manner.
Inherited
Properdin deficiency is an X-linked disorder that also causes susceptibility to Neisseria infections.
C1-inhibitor deficiency or hereditary angioedema will have low C4 with normal C1 levels.
Acquired
Acq |
https://en.wikipedia.org/wiki/Residual%20frame | In video compression algorithms a residual frame is formed by subtracting the reference frame from the desired frame. This difference is known as the error or residual frame. The residual frame normally has less information entropy, due to nearby video frames having similarities, and therefore requires fewer bits to compress.
An encoder will use various algorithms such as motion estimation to construct a frame that describes the differences. This allows a decoder to use the reference frame plus the differences to construct the desired frame.
See also
Motion compensation
References
Video compression |
https://en.wikipedia.org/wiki/Pappalysin-1 | Pappalysin-1, also known as pregnancy-associated plasma protein A, and insulin-like growth factor binding protein-4 protease is a protein encoded by the PAPPA gene in humans. PAPPA is a secreted protease whose main substrate is insulin-like growth factor binding proteins. Pappalysin-1 is also used in screening tests for Down syndrome.
Function
PAPPA encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). PAPPA's proteolytic function is activated upon collagen binding. It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses (fetuses with an abnormal number of chromosomes). For example, low PAPPA may be commonly seen in prenatal screening for Down syndrome. Low levels may alternatively predict issues with the placenta, resulting in adverse complications such as intrauterine growth restriction, preeclampsia, placental abruption, premature birth, or fetal death.
This enzyme catalyses the following chemical reaction:
Cleavage of the Met135-Lys bond in insulin-like growth factor binding protein (IGFBP)-4, and the Ser143-Lys bond in IGFBP-5
This enzyme belongs to the peptidase family M43.
Interactions
Pappalysin-1 has been shown to interact with major basic protein.
Studies conducted at the Royal London Hospital in the United Kingdom, have shown that a marker of D |
https://en.wikipedia.org/wiki/Pawura | Pawura, and also: Pauru, Piwure, Puuru/Puwuru was an Egyptian official of the 1350–1335 BC Amarna letters correspondence. As mentioned in letter no. 171, he was also an Egyptian "archer–commander". In letter no. 289 he is called an "irpi–official". In Egyptian his name means 'the Great One', (Pa-wr/Pa-ur)(letter EA 287:45-"1.-Pa-Ú-Ru")
Pawura's name is referenced in the following letters: (EA for 'el Amarna')
Rib-Haddi–The Rib-Hadda sub-corpus of 68 letters: EA 117, 124, 129, 131, 132, and EA 362.
Aziru–EA 171, by Aziru of Ammuru, Title: "Eager to Serve".
EA 263–EA 263, a short letter. Title: "Robbed of Everything." (author unknown)
Abdi-Heba–EA 287 and EA 289, letters by Abdi-Heba to pharaoh.(see EA 287 here: Photo, EA 287: Reverse)
Pawura's death is mentioned in the Rib-Hadda letters except EA 117, and 124, along with the demise of others, or the warring with the Habiru, or the leaders of Ammuru: (Abdi-Ashirta, or his son, Aziru).
Example letters for: Official Pawura
EA 171, by Aziru of Ammuru--(no. 13 of 13)
EA 171, Title: "Eager to Serve", + (Yanhamu)
[To the king ...: Message of Aziru ...] ... I fall a[t the fee]t of the king, the Sun, my [lord]. [From the very first I ch]ose to enter [the servi]ce of the ki[ng], the [Su]n, my lord, [but Ya]nhamu would not a[ll]ow me. [I s]ent my mes[sen]gers [to] the king, my lord, [but] Yanhamu [stopped th]em on the way, and [they have not got away. May] the gods of the king, my lord, grant that my messengers get away [fr]om Yanh |
https://en.wikipedia.org/wiki/Milkilu | Milkilu, and more properly Milk-ilu, or Milku-ilu, with an alternate version of Ili-Milku (letter 286, by Abdi-Heba of Jerusalem), was the mayor/ruler of Gazru (Gezer) of the 1350–1335 BC Amarna letters correspondence. Adda-danu, and Yapahu were also mayors of Gazru.
Milk-ilu is the author of 5 Amarna letters to the pharaoh of Egypt, EA 267–271, (EA for 'el Amarna'). One letter (EA 369) from the pharaoh to Milk-ilu is known.
EA 369, to Milkilu: "From the Pharaoh to a vassal"
"To Milkilu, the ruler of Gazru: Thus the king. He herewith dispatches to you this tablet (i.e., tablet-letter), saying to you, He herewith sends to you Hanya, the stable (overseer) of the archers, along with everything for the acquisition of beautiful female cupbearers: silver, gold, linen garments: ma-al-ba-ši, carnelian, all sorts of (precious) stones, an ebony chair; all alike, fine things. Total (value): 160 diban. Total: 40 female cupbearers, 40 (shekels of) silver being the price of a female cupbearer. Send extremely beautiful female cupbearers in whom there is no defect (i.e., no guile in their heart), so the king, your lord, will say to you, "this is excellent, in accordance with the order he sent to you." And know that the king is hale like the Sun. For his troops, his ch[ariot]s, his horses, all goes very well. Aman has indeed put the Upper Land, the Lower Land, where the sun rises, where the sun sets, under the feet of the king." —EA 369, lines 1–32 (complete)
Two examples of Milkilu's lett |
https://en.wikipedia.org/wiki/Next%20Byte%20Codes | Next Byte Codes (NBC) is a simple language with an assembly language syntax that can be used to program Lego Mindstorms NXT programmable bricks. The command line compiler outputs NXT compatible machine code, and is supported on Windows, Mac OS and Linux. It is maintained by John Hansen, a Mindstorms Developer Program member.
The NBC compiler is released under the Mozilla Public License. The integrated development environment (IDE) is Bricx Command Center.
The NBC debugger was developed by SorosyDotCom and can be downloaded as freeware.
References
External links
Robotics lecture using NBC
Assembly languages
Lego Mindstorms
Robot programming languages |
https://en.wikipedia.org/wiki/NXC | NXC may refer to:
nxc, NX technology library
Namco × Capcom, a turn-based strategy console game
Not eXactly C, a high level language, similar to C, built on top of the Next Byte Codes compiler
Nuveen California Select Tax-Free Income Portfolio
National Express Coaches
National Express Coventry |
https://en.wikipedia.org/wiki/Ap%C3%A1catorna | Apácatorna is a village in Veszprém county, Hungary.
External links
Street map (Hungarian)
Populated places in Veszprém County |
https://en.wikipedia.org/wiki/Iktaba | Iktaba () is a Palestinian town located four kilometers Northeast of the city of Tulkarm in the Tulkarm Governorate in the northern West Bank. According to the Palestinian Central Bureau of Statistics (PCBS), the town had a population of 2,665 inhabitants in 2007 and 2,997 by 2017. Refugees make-up 33% of the entire population in 1997.
History
In 1265, after the Mamluks had defeated the Crusaders, Iktaba (Sabahiya) was mentioned among the estates which Sultan Baibars granted his followers. The village was given to the emir Alam al-Din Tardaj al-Amadi.
Ottoman era
Iktaba was incorporated into the Ottoman Empire in 1517 with all of Palestine, and in 1596 it appeared in the tax registers under the name of Staba, being in the Nahiya of Qaqun of the Liwa of Nablus. It had a population of 21 households, all Muslims. The villagers paid a fixed tax rate of 33,3% on various agricultural products, such as wheat, barley, summer crops, olive trees, goats and/or beehives, in addition to "occasional revenues" and a press for olive oil or grapes; a total of 4,100 akçe.
In 1870, the French explorer Victor Guérin noted that village, which he called Astaba, was a "Small hamlet located on a high hill. Ancient cisterns testify to the existence here of an ancient locality. Fig trees and pomegranates grow around the dwellings."
In 1882, the PEF's Survey of Western Palestine described it as: "A place to which a certan effendi of Nablus comes down in spring, a sort of 'Azbeh or s |
https://en.wikipedia.org/wiki/Protein%20A/G | Protein A/G is a recombinant fusion protein that combines IgG binding domains of both Protein A and Protein G. Protein A/G contains four Fc binding domains from Protein A and two from Protein G, yielding a final mass of 50,460 daltons. The binding of Protein A/G is less pH-dependent than Protein A, but otherwise has the additive properties of Protein A and G.
Protein A/G binds to all subclasses of human IgG, making it useful for purifying polyclonal or monoclonal IgG antibodies whose subclasses have not been determined. In addition, it binds to IgA, IgE, IgM and (to a lesser extent) IgD. Protein A/G also binds to all subclasses of mouse IgG but does not bind mouse IgA, IgM or serum albumin. This allows Protein A/G to be used for purification and detection of mouse monoclonal IgG antibodies, without interference from IgA, IgM and serum albumin. Mouse monoclonal antibodies commonly have a stronger affinity to the chimeric Protein A/G than to either Protein A or Protein G. Protein A/G also has been used for purification of macaque IgG.
Other antibody binding proteins
In addition to Protein A/G, other immunoglobulin-binding bacterial proteins such as Protein A, Protein G and Protein L are all commonly used to purify, immobilize or detect immunoglobulins. Each of these immunoglobulin-binding proteins has a different antibody binding profile in terms of the portion of the antibody that is recognized and the species and type of antibodies.
References
Proteins |
https://en.wikipedia.org/wiki/Ante%27s%20law | In dentistry, Ante's law is a postulate about crown-to-root ratio put forth by Irwin H. Ante in a thesis paper he wrote in 1926.
Ante's law states that:
"the total periodontal membrane area of the abutment teeth must equal or exceed that of the teeth to be replaced."
Later claims were made that:
"the length of the periodontal membrane attachment of the abutment tooth should be at least one half to two thirds of that of its normal root attachment".
Because of these unsubstantiated, empirical concepts, many teeth were subsequently excluded from suitability as an abutment for fixed partial dentures and double abutments became a popular means of complying with Ante's law.
Ante's law has not been confirmed by long-term clinical trials.
References
Dentistry |
https://en.wikipedia.org/wiki/Protestantism%20in%20Colombia | The National Administrative Department of Statistics (DANE) does not collect religious statistics, and accurate reports are difficult to obtain. However, based on various studies and a survey, about 90% of the population adheres to Christianity, the majority of which (70.9%) are Roman Catholic, while a significant minority (16.7%) adhere to Protestantism (primarily Evangelicalism).
In 2020, figures suggest that Protestants make up 14% of the country's population.
Protestant Christians present in Colombia are Baptists, Lutherans, Mennonites, Nazarenes, Pentecostals and Seventh-day Adventists.
List of Denominations
Alianza Cristiana y Misionera
Assemblies of God
Asociación de Iglesias Hermanos Menonitas de Colombia: 831 (1998)
Church of God Ministry of Jesus Christ International
Church of the Nazarene: 12,860 (1998)
Hermanos en Cristo
Iglesia Cruzada Evangélica
Iglesia de Dios
Iglesia Evangélica Luterana
Misión Evangélica
Mision Indigena
Misión Nuevas Tribus
Presbyterian Church of Colombia
Unión Misionera Evangélica
Seventh-day Adventist Church
Freedom of religion
The constitution provides for freedom of religion and the government generally is in support of this. However, international NGOs have stated that indigenous Protestants face threats, harassment and arbitrary detention in their communities due to their religious beliefs; in particular, Indigenous authorities in the Pizarro and Litoral de San Juan municipalities in the Chocó Department have prohibited the practi |
https://en.wikipedia.org/wiki/Surprise%20%28Crystal%20Waters%20album%29 | Surprise is the debut album by American singer-songwriter Crystal Waters released on June 25, 1991 by Mercury Records. It includes the hit singles "Makin' Happy", "Surprise" and the top ten hit "Gypsy Woman (She's Homeless)", which peaked at number 8 on the US Billboard Hot 100, and number 2 on the UK Singles Chart.
Although the album stalled at number 197 on the US Billboard 200, it performed better in both the club/dance and urban music markets, peaking at number 65 on the Top R&B/Hip-Hop Albums chart. It also peaked at number 23 on the Top Heatseekers chart.
Track listing
Chart positions
Album
Singles
References
1991 debut albums
Crystal Waters albums
Mercury Records albums |
https://en.wikipedia.org/wiki/Autotaxin | Autotaxin, also known as ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (E-NPP 2), is an enzyme that in humans is encoded by the ENPP2 gene.
Function
Autotaxin is a secreted enzyme important for generating the lipid signaling molecule lysophosphatidic acid (LPA). Autotaxin has lysophospholipase D activity that converts lysophosphatidylcholine into LPA.
Autotaxin was originally identified as a tumor cell-motility-stimulating factor; later it was shown to be LPA (which signals through lysophospholipid receptors), the lipid product of the reaction catalyzed by autotaxin, which is responsible for its effects on cell-proliferation.
The protein encoded by this gene functions as a phosphodiesterase. Autotaxin is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants have been identified. Autotaxin is able to cleave the phosphodiester bond between the α and the β position of triphosphate nucleotides, acting as an ectonucleotide phosphodiesterase producing pyrophosphate, as most members of the ENPP family. Importantly, autotaxin also acts as phospholipase, catalyzing the removal of the head group of various lysolipids. The physiological function of autotaxin is the production of the signalling lipid lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumo |
https://en.wikipedia.org/wiki/W.%20B.%20R.%20Lickorish | William Bernard Raymond Lickorish (born 19 February 1938) is a mathematician. He is emeritus professor of geometric topology in the Department of Pure Mathematics and Mathematical Statistics, University of Cambridge, and also an emeritus fellow of Pembroke College, Cambridge. His research interests include topology and knot theory. He was one of the discoverers of the HOMFLY polynomial invariant of links, and proved the Lickorish-Wallace theorem which states that all closed orientable 3-manifolds can be obtained by Dehn surgery on a link.
Education
Lickorish received his Ph.D from Cambridge in 1964; his thesis was written under the supervision of Christopher Zeeman.
Recognition and awards
In 1991, Lickorish received the Senior Whitehead Prize from the London Mathematical Society. Lickorish and Kenneth Millett won the 1991 Chauvenet Prize for their paper "The New Polynomial Invariants of Knots and Links".
Lickorish was included in the 2019 class of fellows of the American Mathematical Society "for contributions to knot theory and low-dimensional topology".
Selected publications
See also
Lickorish twist theorem
Lickorish–Wallace theorem
References
1935 births
Living people
20th-century British mathematicians
21st-century British mathematicians
Topologists
Fellows of Pembroke College, Cambridge
Cambridge mathematicians
Fellows of the American Mathematical Society
Whitehead Prize winners |
https://en.wikipedia.org/wiki/Pulse~Link | Pulse~LINK is a privately held fabless integrated circuit semiconductor corporation headquartered in Carlsbad, California, located just north of San Diego California, in the United States. Pulse~LINK commercializes ultra-wideband (UWB) technology, for both wireless and wired networks.
Company
Pulse~Link developed a UWB technology based on continuous pulsed UWB (C-UWB) for whole-home distribution of interactive high data rate multimedia content over wired, wireless and hybrid networks. One implementation of the technology is designed to coexist with existing CATV signals over existing coax to the home.
Pulse~LINK's CWave implementation of C-UWB provides raw data rates up to a 2.7 Gigabits per second over coaxial cable and wireless networks. It is promoted for its ability to co-exist with CATV signals, as an "overlay" to bring more data to consumer's homes. Pulse~LINK's CWave implementations of C-UWB can support the simultaneous operation of IEEE 1394, Gigabit Ethernet and HDMI-equivalent connections with end-to-end quality of service (QoS).
Pulse~LINK developed a set of integrated circuits for media access control (MAC) and radio frequency (RF) layers, and later brought a single integrated MCM module incorporating the baseband/mac/rf plus system ram.
After joining both the UWB Forum and WiMedia Alliance in 2004, in February 2005, it positioned its technology as a third alternative to the technologies promoted by the after groups.
It had raised $38 million by then.
Demons |
https://en.wikipedia.org/wiki/Semen%20%28disambiguation%29 | Semen may refer to:
Semen, the genital fluid also known as seminal fluid indicating fluid reabsorption in the pinocytotic vessels
Semen (wasp), a wasp genus in the subfamily Encyrtinae
Semen Gresik, the largest cement producing company in Indonesia
Semen (name):
Semen or Xemen, a medieval Basque and neighbour given name
a popular Ukrainian given name (Семен)
a romanization of Russian given names Семён (Semyon) or Симон (Simon)
Semen Korsakov
See also
Seamen, the plural of seaman
Semem Creek
Semens, a commune in the Gironde department in southwestern France
Siemens, German industrial and technology conglomerate |
https://en.wikipedia.org/wiki/IMSA%20GTP | Grand Touring Prototype (GTP) is the name of a former classification designated to sports prototypes in sports car racing competing in the IMSA GT Championship, maintained by IMSA between 1981 and 1993. The early cars were based on the almost same identical ruleset as the FIA's Group C category, but eventually evolved into a separate category. It was the successor to the Grand Touring Experimental (GTX) class, which were based on FIA Group 5 and Group 6 cars.
The IMSA GTP moniker was revived in 2023 to replace DPi as the top class of the IMSA SportsCar Championship for the merger of DPi and the World Endurance Championship Hypercar class.
History
GTP era
In 1981, purpose-built GTP cars (Grand Touring Prototypes) appeared in the championship, and were similar to the new FIA Group C cars which would be introduced to the World Endurance Championship from 1982. The main difference between the two categories was that the former had no emphasis on fuel consumption which was highlighted by Derek Bell saying "Race fans do not come to races to watch an economy run." Brian Redman was the first GTP champion, driving a Lola T600 with a Chevrolet engine. March also fielded prototypes, with Al Holbert winning the 1983 championship with a Chevrolet powered car, changing to Porsche power later in the season; and Randy Lanier a year later with Chevrolet power. 1984 also saw the introduction of the Porsche 962, which dominated the series from '85 to '87. Nissan then took control of the ser |
https://en.wikipedia.org/wiki/ABC%20Northern%20Tasmania | ABC Northern Tasmania (call sign: 7NT) is the ABC Local Radio station for northern Tasmania, based in Launceston, owned by the Australian Broadcasting Corporation. It broadcasts on the frequency of 91.7 MHz on the FM band from Mount Barrow at a power of 192 kW which covers much of Northern Tasmania.
In addition, the station has many low power repeater stations across the state including:
Bicheno 89.7 MHz
Burnie 102.5 MHz
Devonport 100.5 MHz
Fingal 1161 kHz AM
King Island 88.6 MHz
Lileah 91.3 MHz
Queenstown/Zeehan 90.5 MHz
Rosebery 106.3 MHz
Savage River 104.1 MHz
St Helens 1584 kHz AM
St Marys 102.7 MHz
Strahan 107.5 MHz
Swansea 106.1 MHz
Waratah 103.3 MHz
Weldborough 97.3 MHz
Launceston CBD 102.7 MHz
History
ABC Northern Tasmania was the ABC radio's first regional station in Launceston. It was opened by Prime Minister Joseph Lyons on 3 August 1935.
7NT moved from AM (711 kHz) to FM (91.7 MHz) in 2006.
References
Northern Tasmania
Radio stations in Tasmania |
https://en.wikipedia.org/wiki/Mean%20reciprocal%20rank | The mean reciprocal rank is a statistic measure for evaluating any process that produces a list of possible responses to a sample of queries, ordered by probability of correctness. The reciprocal rank of a query response is the multiplicative inverse of the rank of the first correct answer: 1 for first place, for second place, for third place and so on. The mean reciprocal rank is the average of the reciprocal ranks of results for a sample of queries Q:
where refers to the rank position of the first relevant document for the i-th query.
The reciprocal value of the mean reciprocal rank corresponds to the harmonic mean of the ranks.
Example
For example, suppose we have the following three sample queries for a system that tries to translate English words to their plurals. In each case, the system makes three guesses, with the first one being the one it thinks is most likely correct:
Given those three samples, we could calculate the mean reciprocal rank as (1/3 + 1/2 + 1)/3 = 11/18 or about 0.61.
If none of the proposed results are correct, reciprocal rank is 0. Note that only the rank of the first relevant answer is considered, possible further relevant answers are ignored. If users are interested also in further relevant items, mean average precision is a potential alternative metric.
See also
Information retrieval
Question answering
References
Summary statistics
Information retrieval evaluation |
https://en.wikipedia.org/wiki/Photographic%20emulsion | Photographic emulsion is a light-sensitive colloid used in film-based photography. Most commonly, in silver-gelatin photography, it consists of silver halide crystals dispersed in gelatin. The emulsion is usually coated onto a substrate of glass, films (of cellulose nitrate, cellulose acetate or polyester), paper, or fabric. The substrate is often flexible and known as a film base.
Photographic emulsion is not a true emulsion, but a suspension of solid particles (silver halide) in a fluid (gelatin in solution). However, the word emulsion is customarily used in a photographic context. Gelatin or gum arabic layers sensitized with dichromate used in the dichromated colloid processes carbon and gum bichromate are sometimes called emulsions. Some processes do not have emulsions, such as platinum, cyanotype, salted paper, or kallitype.
Components
Photographic emulsion is a fine suspension of insoluble light-sensitive crystals in a colloid sol, usually consisting of gelatin. The light-sensitive component is one or a mixture of silver halides: silver bromide, chloride and iodide. The gelatin is used as a permeable binder, allowing processing agents (e.g., developer, fixer, toners, etc.) in aqueous solution to enter the colloid without dislodging the crystals. Other polymer macromolecules are often blended, but gelatin has not been entirely replaced. The light-exposed crystals are reduced by the developer to black metallic silver particles that form the image. Color films and pap |
https://en.wikipedia.org/wiki/Hydrophobic-polar%20protein%20folding%20model | The hydrophobic-polar protein folding model is a highly simplified model for examining protein folds in space. First proposed by Ken Dill in 1985, it is the most known type of lattice protein: it stems from the observation that hydrophobic interactions between amino acid residues are the driving force for proteins folding into their native state. All amino acid types are classified as either hydrophobic (H) or polar (P), and the folding of a protein sequence is defined as a self-avoiding walk in a 2D or 3D lattice. The HP model imitates the hydrophobic effect by assigning a negative (favorable) weight to interactions between adjacent, non-covalently bound H residues. Proteins that have minimum energy are assumed to be in their native state.
The HP model can be expressed in both two and three dimensions, generally with square lattices, although triangular lattices have been used as well. It has also been studied on general regular lattices.
Randomized search algorithms are often used to tackle the HP folding problem. This includes stochastic, evolutionary algorithms like the Monte Carlo method, genetic algorithms, and ant colony optimization. While no method has been able to calculate the experimentally determined minimum energetic state for long protein sequences, the most advanced methods today are able to come close.
For some model variants/lattices, it is possible to compute optimal structures (with maximal number of H-H contacts) using constraint programming techniques |
https://en.wikipedia.org/wiki/Hydrocolpos | Hydrocolpos is the distension of the vagina caused by accumulation of fluid due to congenital vaginal obstruction. The obstruction is often caused by an imperforate hymen or less commonly a transverse vaginal septum. The fluid consists of cervical and endometrial mucus or in rare instances urine accumulated through a vesicovaginal fistula proximal to the obstruction. In some cases, it is associated with Bardet-Biedl Syndrome. If it occurs in prepubertal girls, it may show up as abdominal swelling. It may be detected by using ultrasound. Prenatal diagnosis and early newborn imaging studies leads to early detection and treatment of these cases. It may also present at birth as a distended lower abdomen and vagina. It also associated with vaginal atresia. A high index of suspicion for hydrocolpos in a newborn presenting with fetal diagnosis of infraumbilical abdominal mass will facilitate timely intervention and prevention of complications.
References
Pediatrics
Women's health |
https://en.wikipedia.org/wiki/Qurnet%20Murai | Qurnet Murai is a necropolis located on the West Bank of the Nile at Thebes, Egypt, just to the south of Sheikh Abd el-Qurna.
It was also used as a cemetery for officials of the New Kingdom administration in Thebes.
Tombs at Qurnet Murai
TT40 – Amenhotep-Huy, Viceroy of Kush; reign of Tutankhamun
TT221 – Hormin, Scribe of troops in the palace of the king on the West of Thebes; reign of Ramesses III
TT222 – Heqamaatranakht called Turo, High priest of Monthu, 20th Dynasty
TT223 – Karakhamon, first ka(?)–priest, Late Period
TT235 – Userhet, High priest of Monthu, 20th Dynasty
TT270 – Amenemwia, wab–priest, lector–priest of Ptah–Sokar, 19th Dynasty
TT271 – Nay, Royal scribe, reign of Aye.
TT272 – Khaemopet Divine Father of Amun in the west, lector–priest of the Sokar temple, Ramesside Period, 20th Dynasty
TT273 – Sayemiotf, Scribe in the estate of his lord, Ramesside Period
TT274 – Amenwahsu, High priest of Monthu of Tod and of Thebes, sem–priest in the Ramesseum in the estate of Amun, reign of Ramesses II – Merenptah, 19th dynasty
TT275 – Sebekmose, Head wab–priest, Divine Father in the temples of king Amenhotep III and Sokar, Ramesside Period
TT276 – Amenemopet, Overseer of the treasury of gold and silver, Judge, Overseer of the cabinet, reign of Thutmose IV, 18th Dynasty
TT277 – Amenemonet, Divine father in the reign of king Amenhotep III, 19th Dynasty
TT278 – Amenemheb, Herdsman of Amun–Ra, Ramesside Period, 20th Dynasty
TT380 – Ankhefen–Re–Horakhty, Chief i |
https://en.wikipedia.org/wiki/Alpha-enolase | Enolase 1 (ENO1), more commonly known as alpha-enolase, is a glycolytic enzyme expressed in most tissues, one of the isozymes of enolase. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase, in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy.
Structure
ENO1 is one of three enolase isoforms, the other two being ENO2 (ENO-γ) and ENO3 (ENO-β). Each isoform is a protein subunit that can hetero- or homodimerize to form αα, αβ, αγ, ββ, and γγ dimers. The ENO1 gene spans 18 kb and lacks a TATA box while possessing multiple transcription start sites. A hypoxia-responsive element can be found in the ENO1 promoter and allows the enzyme to function in aerobic glycolysis and contribute to the Warburg effect in tumor cells.
Relationship to Myc-binding protein-1
The mRNA transcript of the ENO1 gene can be alternatively translated into a cytoplasmic protein, with a molecular weight of 48 kDa, or a nuclear protein, with a molecular weight of a 37 kDa. The nuclear form was previously identified as Myc-binding protein-1 (MBP1), which downregulates the pr |
https://en.wikipedia.org/wiki/WOBE | WOBE (100.7 FM, "100.7 Radio Now") is a radio station broadcasting a top 40/CHR format. Licensed to Crystal Falls, Michigan, with studios in Iron Mountain, it first began broadcasting in 1999, carrying the Oldies Radio package from ABC Radio Networks.
History
On June 14, 2012 WOBE changed their format from classic hits (as B-100.7) to Top 40/contemporary hit radio, branded as "100.7 Radio Now".
Sources
Michiguide.com - WOBE History
References
External links
OBE-FM
Contemporary hit radio stations in the United States
Radio stations established in 1996 |
https://en.wikipedia.org/wiki/WGDN%20%28AM%29 | WGDN (1350 AM) is a radio station licensed to Gladwin, Michigan broadcasting a religious format. It is a daytime only station broadcasting on a frequency of 1350 kHz at a power output of 250 watts, non-directional.
History
Beginnings
WGDN's construction permit was issued on November 28, 1973, to Gladwin Broadcasting Company, headed by George Benko, a resident of Croswell, in Michigan's Thumb Area. Benko today owns Sanilac Broadcasting, licensee of WMIC, WTGV, and WBGV.
The station made its debut on December 7, 1974 as WJEB, broadcasting a country music format. The station did broadcast on its current frequency, but did so using a two-tower directional antenna system, allowing it to operate with an output power of 1,000 watts, but still daytime only. The station's studios, offices and transmitter facility were located at 3601 West Woods Road in Gladwin, and remain there today.
On December 10, 1974, shortly after its initial sign-on, the FCC granted WGDN pre-sunrise authorization to operate at 350 watts two hours before local sunrise, allowing it to sign-on at 6am year-round, rather than local sunrise time.
In 1977, Gladwin Broadcasting Company was granted a construction permit for an FM station. That station, WGMM, went on the air February 7, 1979 with an easy-listening format.
Sale to Apple Broadcasting
In December 1986, Gladwin Broadcasting Company agreed to sell WGDN and WGMM to Apple Broadcasting Company, for $75,000. The company was headed by Michael Baker, w |
https://en.wikipedia.org/wiki/French%E2%80%93American%E2%80%93British%20classification | The French–American–British (FAB) classification systems refers to a series of classifications of hematologic diseases. It is based on the presence of dysmyelopoiesis and the quantification of myeloblasts and erythroblasts.
It was first produced in 1976.
Types include:
FAB classification of acute lymphoblastic leukemias: L1–L3 (three subtypes)
FAB classification of acute myeloid leukemias: M0–M7 (eight subtypes)
FAB classification of myelodysplastic syndromes
Updates continued through at least 1989.
References
Hematologic neoplasms |
https://en.wikipedia.org/wiki/Marlborough%20Farms | Marlborough Farms is the first album by the Brooklyn indie pop band The Ladybug Transistor. It was released on October 4, 1996.
The album was named after vocalist/guitarist Gary Olson's home studio.
Critical reception
Douglas Wolk, in Salon, called the album "a competent Pavement rip-off with some curious touches in its arrangements, like singer Gary Olson's trumpet parts."
Track listing
"Wheel"
"(Theme To) Lout"
"Magic Forest Report"
"Sneedle"
"Seadrift"
"Blaze"
"95 Miles Per Hour"
"Land"
"Twice a Lifetime"
"Song for Vocoder and Trumpet"
References
1996 debut albums
The Ladybug Transistor albums |
https://en.wikipedia.org/wiki/Beverley%20Atonale | Beverley Atonale is the second album by the Brooklyn indie pop band The Ladybug Transistor. It was released on February 11, 1997.
Critical reception
The Chicago Reader wrote that "the young quartet's reach [exceeded] their grasp: aiming for the orchestral splendor of 60s pop, they got a handful of flat, rinky-dink indie rock played on too many instruments." CMJ New Music Monthly wrote that "there's something really delightful about the idea that four people can create their own little Pet Sounds."
Track listing
"Here Is Your Space"
"Rushes Of Pure Spring"
"Windy"
"The Swedish Libra And You"
"This Order Is Tall"
"Music For Tennis Courts"
"Your Wagging Tail (Single Space)"
"Stuck"
"Forest Marching Song"
"The Occasional"
"It Will Be A Lifetime"
"Thoughts Of You"
"The Swedish Libra II"
References
1997 albums
The Ladybug Transistor albums
Merge Records albums |
https://en.wikipedia.org/wiki/The%20Albemarle%20Sound | The Albemarle Sound is the third album by the Brooklyn, New York, indie pop band The Ladybug Transistor. It was released on March 23, 1999.
Critical reception
The A.V. Club wrote: "Rich and instantly accessible, The Ladybug Transistor has created a sound, regardless of source material, that's entirely its own." The Hartford Courant called the album "a collection of panoramic, pastoral pop that reflects the sights and sounds of their world with the same loving texture and color that Brian Wilson illustrated the California shore with."
Track listing
"Oriental Boulevard"
"Six Times"
"Meadowport Arch"
"Today Knows"
"The Great British Spring"
"Like A Summer Rain"
"The Swimmer"
"Cienfuegos"
"The Automobile Song"
"Oceans In The Hall"
"Vale Of Cashmere"
"Aleida's Theme"
References
1999 albums
The Ladybug Transistor albums
Merge Records albums |
https://en.wikipedia.org/wiki/Argyle%20Heir | Argyle Heir is a studio album by the American indie pop band the Ladybug Transistor. It was released on May 22, 2001, via Merge Records.
Critical reception
The Austin American-Statesman wrote that "these Brooklyn nerds are at their best when they keep it simple, as on 'Echoes', a twangy number that sounds like an outtake from the Byrds' Sweetheart of the Rodeo, or on 'Going Up North', a waltz instrumental with warm Mellotron tones and, uh, sleigh bells (which make several appearances throughout the record)."
Track listing
"Fires On The Ocean"
"Echoes"
"Perfect For Shattering"
"Going Up North (Icicles)"
"Wooden Bars"
"Catherine Elizabeth"
"Nico Norte"
"Words Hang In The Air"
"Fjords Of Winter"
"In A Certain Place"
"Brighton Bound"
"The Reclusive Hero"
"The Glass Pane"
"Caton Gardens"
Personnel
Gary Olson - vocals and trumpet
Jeff Baron - guitar
Jennifer Baron - bass guitar
Sasha Bell - vocals, piano, organ and flute
San Fadyl - drums
Julia Rydholm - violin
References
2001 albums
The Ladybug Transistor albums
Merge Records albums |
https://en.wikipedia.org/wiki/The%20Ladybug%20Transistor%20%28album%29 | The Ladybug Transistor is an album by the Brooklyn indie pop band The Ladybug Transistor. It was released in 2003 by Merge Records.
Critical reception
The Encyclopedia of Popular Music wrote that "the blend of 70s-era AOR rock and wistful chamber pop helped make the album one of the year's most pleasant surprises." The Tucson Weekly called the album "the band's best record yet," writing that it "takes off with a flourish and spins through 13 songs played on 12-string guitars, keyboards, strings and horns."
Track listing
"These Days In Flames"
"In December"
"3=Wild"
"Song For The Ending Day"
"Choking On Air"
"The Places You'll Call Home"
"Gospel"
"Please Don't Be Long"
"NY-San Anton"
"Hangin' On The Line"
"A Burial At Sea"
"Splendor In The Grass"
"The Last Gent"
Personnel
Gary Olson - vocals and trumpet
Jeff Baron - guitar
Sasha Bell - vocals, piano, organ and flute
San Fadyl - drums
Julia Rydholm - bass guitar and violin
References
2003 albums
The Ladybug Transistor albums
Merge Records albums |
https://en.wikipedia.org/wiki/Can%27t%20Wait%20Another%20Day | Can't Wait Another Day is an album by the Brooklyn indie pop band The Ladybug Transistor, and the last with the drummer San Fadyl. It was released on June 5, 2007, by Merge Records.
Critical reception
Exclaim! wrote that "this is far from a bad album--in fact, it's pretty good--it's just somewhat disappointing to see the band shrink away from the unabashed joyfulness they once made their own." The Guardian wrote that "long-term fans will envelop themselves happily in the album's soft loveliness, despite a feeling that some more memorable moments would have been welcome."
Track listing
"Always on the Telephone"
"I'm Not Mad Enough"
"Here Comes the Rain"
"Terry"
"This Old Chase"
"For No Other"
"Three Days from Now"
"In-Between"
"So Blind"
"Broken Links"
"California Stopover"
"Lord, Don't Pass Me By"
Personnel
Gary Olson - vocals, guitar and trumpet
Jeff Baron - guitar
Ben Crum - guitar
San Fadyl - drums
Kyle Forester - piano, organ and backing vocals
Julia Rydholm - bass guitar and backing vocals
References
2007 albums
The Ladybug Transistor albums
Merge Records albums |
https://en.wikipedia.org/wiki/Lorentz%20curve | Lorentz curve may refer to
the Cauchy–Lorentz distribution, a probability distribution
the Lorenz curve, a graphical representation of the inequality in a quantity's distribution |
https://en.wikipedia.org/wiki/Histidine%20ammonia-lyase | Histidine ammonia-lyase (EC 4.3.1.3, histidase, histidinase) is an enzyme that in humans is encoded by the HAL gene. It converts histidine into ammonia and urocanic acid. Its systematic name is L-histidine ammonia-lyase (urocanate-forming).
Function
Histidine ammonia-lyase is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. The reaction is catalyzed by 3,5-dihydro-5-methyldiene-4H-imidazol-4-one (MIO), an electrophilic cofactor which is formed autocatalytically by cyclization of the protein backbone of the enzyme.
Pathology
Mutations in the gene for histidase are associated with histidinemia and urocanic aciduria.
See also
Phenylalanine ammonia-lyase, another enzyme that contains the MIO cofactor
References
Further reading
External links
EC 4.3.1 |
https://en.wikipedia.org/wiki/Urocanase | Urocanase (also known as imidazolonepropionate hydrolase or urocanate hydratase) is the enzyme () that catalyzes the second step in the degradation of histidine, the hydration of urocanate into imidazolonepropionate.
Urocanase is coded for by the UROC1 gene, located on the 3rd chromosome in humans. The protein itself is composed of 676 amino acids which then fold, producing the final product which has 2 identical subunits, making the enzyme a homodimer.
To catalyze the hydrolysis of urocanate in the catabolic pathway of L-histidine the enzyme utilizes its two NAD+ (Nicotinamide Adnene Dinucleotide) groups. The NAD+ groups act as electrophiles, attaching to the top carbon of the urocanate which leads to sigmatropic rearrangement of the urocanate molecule. This rearrangement allows for the addition of a water molecule, converting the urocanate into 4,5-dihydro-4-oxo-5-imidazolepropanoate.
urocanate + H2O 4,5-dihydro-4-oxo-5-imidazolepropanoate
Inherited deficiency of urocanase leads to elevated levels of urocanic acid in the urine, a condition known as urocanic aciduria.
Urocanase is found in some bacteria (gene hutU), in the liver of many vertebrates and has also been found in the plant Trifolium repens (white clover). Urocanase is a protein of about 60 Kd, it binds tightly to NAD+ and uses it as an electrophil cofactor. A conserved cysteine has been found to be important for the catalytic mechanism and could be involved in the binding of the NAD+.
References
External |
https://en.wikipedia.org/wiki/Addaya | Addaya was an Egyptian commissioner during the period of the Amarna letters correspondence (1350–1335 BC). The majority of the Amarna letters were written to the pharaoh of Egypt during a 15-20 year(?) time period.
Addaya is only referenced in four EA Amarna letters (EA for 'el Amarna'). He is in letter EA 254, no. 3 of 3 by Labaya, the person who was aligned with the Habiru of Canaan, the Habiru being one of the main topics of the entire body of Amarna letters. Addaya is also in three letters by Abdi-Heba of Jerusalem, (called Uru-salim in the Amarna letters – EA 289, URU-Ú-ru-sa-lim, "(City)-Uru-salim").
Because Addaya is only mentioned in the letters of Uru-salim, and Šakmu-(of Labaya, modern Shechem-(Nablus)), it can be assumed that Addaya only did business in southern Canaan, or at least in the area of Jerusalem.
Letters for Commissioner: Addaya
EA 287, title: "A very serious crime"
Letter no. 3 of 6 from Abdi-Heba, beginning in the middle of the letter:
"....
"With regard to the Kassites, may the king make inquiry of the commissioners. Though the house is well fortified, they attempted a very serious crime. They [t]ook their tools-(men and materiel), and I had to seek shelter by a support for the roof: ga-ag-gi. A[nd so i]f he is going to send [troop]s into [Urusalim], let them come with [a garrison for] (regular) service. May the king provide for them; [all] of the land might be in dire straits on their account. May the king inquire about the[m. Let there be] much |
https://en.wikipedia.org/wiki/Alveolar%E2%80%93arterial%20gradient | The Alveolar–arterial gradient (A-, or A–a gradient), is a measure of the difference between the alveolar concentration (A) of oxygen and the arterial (a) concentration of oxygen. It is a useful parameter for narrowing the differential diagnosis of hypoxemia.
The A–a gradient helps to assess the integrity of the alveolar capillary unit. For example, in high altitude, the arterial oxygen is low but only because the alveolar oxygen () is also low. However, in states of ventilation perfusion mismatch, such as pulmonary embolism or right-to-left shunt, oxygen is not effectively transferred from the alveoli to the blood which results in an elevated A-a gradient.
In a perfect system, no A-a gradient would exist: oxygen would diffuse and equalize across the capillary membrane, and the pressures in the arterial system and alveoli would be effectively equal (resulting in an A-a gradient of zero). However even though the partial pressure of oxygen is about equilibrated between the pulmonary capillaries and the alveolar gas, this equilibrium is not maintained as blood travels further through pulmonary circulation. As a rule, is always higher than by at least 5–10 mmHg, even in a healthy person with normal ventilation and perfusion. This gradient exists due to both physiological right-to-left shunting and a physiological V/Q mismatch caused by gravity-dependent differences in perfusion to various zones of the lungs. The bronchial vessels deliver nutrients and oxygen to certain lung |
https://en.wikipedia.org/wiki/Radio%20Narvik | Radio Narvik was a local radio station which covered the whole of Ofoten, including Narvik, Ankenes, Ballangen and Bjerkvik. The frequency was FM 103,5 and 150,5 in all areas. It was also possible to listen via internet radio.
In 2005 Radio Narvik was bought by the newspaper Fremover, becoming part of Jærradiogruppen AS. In December 2008, the radio station was closed down due to lack of income.
External links
Radio Narvik (Norwegian)
Radio stations in Norway
Radio stations disestablished in 2008
Defunct mass media in Norway |
https://en.wikipedia.org/wiki/Viverroidea | Viverroidea is a clade within feliformia, containing both the family Viverridae, and the superfamily Herpestoidea.
Classification
Infraorder Viverroidea
Family Viverridae (civets and allies)
Superfamily Herpestoidea
Family Eupleridae (Malagasy carnivorans)
Family Herpestidae (mongooses and allies)
Family Hyaenidae (hyenas and aardwolf)
Family †Lophocyonidae
Family †Percrocutidae
Phylogenetic tree
The phylogenetic relationships of Viverroidea are shown in the following cladogram:
References
Mammal infraorders
Mammal taxonomy
Taxa named by John Edward Gray |
https://en.wikipedia.org/wiki/Cobbler%20Creek%20Recreation%20Park | Cobbler Creek Recreation Park is a protected area located in South Australia about north of the Adelaide city centre in the suburb of Salisbury East. Originally part of the lands of the Kaurna aboriginal people, it was farmed from European settlement of South Australia until the declaration of the park in 1989.
The park provides an open space barrier between Golden Grove and the suburbs of Salisbury, has dams to mitigate flooding and is a significant site for both public recreation and native flora and fauna conservation. It is bounded by main roads and bisected by a four-lane main connecting road.
Structure and climate
Cobbler Creek Recreation Park is a protected area located about north of the Adelaide city centre within the suburb of Salisbury East. The park is bounded by Bridge and Smith roads, and Green Valley Drive. The Grove Way, a major divided road, runs through the park with a pedestrian underpass connecting the two park sections. The park is open to the public and includes three formed walking trails and two ruins. The remains of William Pedler's home "Trevalsa" and another's called "Teakles House" lie next to one of the trails. There are no public facilities except for benches, signage and picnic tables. "Kelway House", originally belonging to the Kelway Park farm that occupied much of the park, remains as office accommodation for park management staff.
The park lies on the border between the dry northern Adelaide Plains and the wetter Mount Lofty Ranges. |
https://en.wikipedia.org/wiki/Plateau%20potentials | Plateau potentials, caused by persistent inward currents (PICs), are a type of electrical behavior seen in neurons.
Spinal Cord
Plateau potentials are of particular importance to spinal cord motor systems. PICs are set up by the influence of descending monoaminergic reticulospinal pathways. Metabotropic neurotransmitters, via monoaminergic input such as 5-HT and norepinephrine, modulate the activity of dendritic L-type Calcium channels that allow a sustained, positive, inward current into the cell. This leads to a lasting depolarisation. In this state, the cell fires action potentials independent of synaptic input. The PICs can be turned off via the activation of high-frequency inhibitory input at which point the cell returns to a resting state.
Olfactory Bulb
Periglomerular cells, inhibitory interneurons that surround and innervate olfactory glomeruli, have also been shown to exhibit plateau potentials.
Cortex and Hippocampus
Plateau potentials are also seen in the cortical, and hippocampal pyramidal neurons. Using iontophoretic, or two-photon glutamate uncaging experiments, it has been discovered that these plateau potentials include activities of voltage dependent calcium channels and NMDA receptors.
References
Electrophysiology
Action potentials |
https://en.wikipedia.org/wiki/Yanhamu | Yanhamu, also Yenhamu, and Enhamu, was an Egyptian commissioner of the 1350-1335 BC Amarna letters correspondence.
Yanhamu is referenced in 16 of the 60–letter "Rib-Hadda of Gubla"-(Byblos) sub-corpus, and also 12 additional letters.
Letters referencing commissioner Yanhamu
Milkilu's EA 270, "Extortion"
Letter no. 4 of 5 to Pharaoh, from "Milkilu of Gazru"-(modern Gezer):
Milkilu's EA 271, "The Power of the 'Apiru"
Milkilu letter no. 5 of 5 to Pharaoh:
Referenced Amarna letters to Yanhamu
The largest sub-corpus of Amarna letters is from the Rib-Haddi corpus: namely "Rib-Hadda of Gubla"-(Byblos). 16 of Rib-Haddi's letters reference Yanhamu, (EA for 'el Amarna').
Letters EA 82-132(16)the Rib-Hadda/Byblos letters-(w/out-EA 98)
EA 82—
EA 85—
EA 86—
EA 98—
EA 102—
EA 105—
EA 106—
EA 109—
EA 116—
EA 117—
EA 118—
EA 127—
EA 131—
EA 132—See: Pahura
Other letters:
EA 98—See: Yapa-Hadda
----
EA 171—See: Pawura
EA 215—
EA 256—
EA 270—Milkilu no. 4 of 5 to pharaoh.
EA 271—Milkilu no. 5 of 5 to pharaoh.
EA 283—See: Šuwardata
EA 284—
EA 285—
EA 286—
EA 289—See: Pawura
EA 286—See: Yabitiri
EA 366—See: Šuwardata
See also
Milkilu
Rib-Hadda of Gubla/Byblos
Amarna letters
Text corpus
References
Moran, William L. The Amarna Letters. Johns Hopkins University Press, 1987, 1992. (softcover, )
Amarna letters officials |
https://en.wikipedia.org/wiki/Digital%20down%20converter | In digital signal processing, a digital down-converter (DDC) converts a digitized, band-limited signal to a lower frequency signal at a lower sampling rate in order to simplify the subsequent radio stages. The process can preserve all the information in the frequency band of interest of the original signal. The input and output signals can be real or complex samples. Often the DDC converts from the raw radio frequency or intermediate frequency down to a complex baseband signal.
Architecture
A DDC consists of three subcomponents: a direct digital synthesizer (DDS), a low-pass filter (LPF), and a downsampler (which may be integrated into the low-pass filter).
The DDS generates a complex sinusoid at the intermediate frequency (IF). Multiplication of the intermediate frequency with the input signal creates images centered at the sum and difference frequency (which follows from the frequency shifting properties of the Fourier transform). The lowpass filters pass the difference (i.e. baseband) frequency while rejecting the sum frequency image, resulting in a complex baseband representation of the original signal. Assuming judicious choice of IF and LPF bandwidth, the complex baseband signal is mathematically equivalent to the original signal. In its new form, it can readily be downsampled and is more convenient to many DSP algorithms.
Any suitable low-pass filter can be used including FIR, IIR and CIC filters. The most common choice is a FIR filter for low amounts of decima |
https://en.wikipedia.org/wiki/List%20of%20CSI%3A%20Miami%20characters | List of characters for the CBS television series, CSI: Miami.
Equations
During CSI: Miamis opening credits, several actors' names morph in and out of equations.
Notable cast members
CSI: Miami ran for ten seasons between 2002 and 2012, and featured a cast of thirteen regulars. David Caruso, as Lieutenant Horatio Caine, was afforded the starring credit, while Emily Procter was credited second to him. Kim Delaney, the female lead in the episodes she appeared, was credited as and, while Rory Cochrane was afforded this credit following his departure, despite being previously credited as with. Also holding and positions were Adam Rodriguez, during seasons 9 and 10 (he was previously credited directly following Procter), and Eddie Cibrian during season 8. Sofia Milos (season 3), Khandi Alexander (seasons 1–6), Jonathan Togo (seasons 3–10), Rex Linn (seasons 5–10), Eva LaRue (seasons 5–10), Megalyn Echikunwoke (season 7), and Omar Benson Miller (seasons 8–10) were credited consistently in that order.
Crossover characters
CSI: Miami hosted several crossover episodes during its ten seasons on air. Gary Sinise, as Detective Mac Taylor, and Melina Kanakaredes as his partner, Detective Stella Bonasera, were introduced during a 2004 episode of CSI: Miami, as were the rest of the CSI: NY cast. Sinise reprised his role during Miamis fourth season, while CSI: Crime Scene Investigation alumnus Laurence Fishburne appeared as his established character during part one of a three part CSI: |
https://en.wikipedia.org/wiki/Pirissi%20and%20Tulubri | Pirissi and Tulubri are a pair of messengers of the 1350–1335 BC Amarna letters correspondence. Pirissi and Tulubri are the messengers of King Tushratta of Mitanni, and are referenced in Amarna letters EA 27, 28, and EA 29, (EA for 'el Amarna').
Queen Tiye of the letter is the Great Royal Wife of Amenhotep III-(Akhenaten's father–(Akhenaten=Amenhotep IV)). The letter EA 28 is by King Tushratta of Mitanni, sent to Akhenaten, King of ancient Egypt.
Egyptian docket notation (in black), reverse of EA 23
Shortly after Amenhotep IV-(Akhenaten) became Pharaoh of Egypt, Tushratta wrote letters(?) to Tiye his mother. The "docket" on the reverse of EA 23 states the following:
Regnal 2?-[year], first month of the Growing season, day 5?, when One(i.e. 1="the King") was in the Southern City (=Thebes) in the estate of "Rejoicing in the Horizon". Copy of the Naharin letter which the messenger Pirizzi (and) the messenger [Tulubri] brought. –(complete)
The letters of Pirissi and Tulubri
Letter no. 12 of 13 by Tushratta to pharaoh:
EA 28, Title: "Messengers detained and a protest"
Letter no. 12 of 13-(to Akhenaten): (See here:
Para I
Say to Naphurereya-(Amenhotep IV), the king of Egyp[t], my brother, my son–in–law, who lo[ves me] and whom I love: Thus Tušratta, the king of Mittan[i] , your father–in–law, who loves you, your brother. For me all goes well-(šalāmu). For you may all go well. For your household, for Teye, your mother, the mistress of Egypt-("Mizri", see: Mizraim), for Tadu-H |
https://en.wikipedia.org/wiki/Ubiquinol | A ubiquinol is an electron-rich (reduced) form of coenzyme Q (ubiquinone). The term most often refers to ubiquinol-10, with a 10-unit tail most commonly found in humans.
The natural ubiquinol form of coenzyme Q is 2,3-dimethoxy-5-methyl-6-poly prenyl-1,4-benzoquinol, where the polyprenylated side-chain is 9-10 units long in mammals. Coenzyme Q10 (CoQ10) exists in three redox states, fully oxidized (ubiquinone), partially reduced (semiquinone or ubisemiquinone), and fully reduced (ubiquinol). The redox functions of ubiquinol in cellular energy production and antioxidant protection are based on the ability to exchange two electrons in a redox cycle between ubiquinol (reduced) and the ubiquinone (oxidized) form.
Characteristics
Because humans can synthesize ubiquinol, it is not classed as a vitamin.
Bioavailability
It is well-established that CoQ10 is not well absorbed into the body, as has been published in many peer-reviewed scientific journals. Since the ubiquinol form has two additional hydrogens, it results in the conversion of two ketone groups into hydroxyl groups on the active portion of the molecule. This causes an increase in the polarity of the CoQ10 molecule and may be a significant factor behind the observed enhanced bioavailability of ubiquinol.
Content in foods
Varying amounts of ubiquinol are found in different types of food. An analysis of a range of foods found ubiquinol to be present in 66 out of 70 items and accounted for 46% of the total coenzyme Q10 in |
https://en.wikipedia.org/wiki/Glutamyl%20aminopeptidase | Glutamyl aminopeptidase (, aminopeptidase A, aspartate aminopeptidase, angiotensinase A, glutamyl peptidase, Ca2+-activated glutamate aminopeptidase, membrane aminopeptidase II, antigen BP-1/6C3 of mouse B lymphocytes, L-aspartate aminopeptidase, angiotensinase A2) is an enzyme encoded by the gene. Glutamyl aminopeptidase has also recently been designated CD249 (cluster of differentiation 249).
Glutamyl aminopeptidase is a zinc-dependent membrane-bound aminopeptidase that catalyzes the cleavage of glutamatic and aspartatic amino acid residues from the N-terminus of polypeptides. The enzyme degrades vasoconstricting angiotensin II into angiotensin III and therefore helps to regulate blood pressure.
References
External links
The MEROPS online database for peptidases and their inhibitors: M01.003
Clusters of differentiation
Zinc enzymes |
https://en.wikipedia.org/wiki/Glutamate%20carboxypeptidase | Glutamate carboxypeptidase (, carboxypeptidase G, carboxypeptidase G1, carboxypeptidase G2, glutamyl carboxypeptidase, N-pteroyl-L-glutamate hydrolase) is an enzyme. This enzyme catalyses the following chemical reaction
Release of C-terminal glutamate residues from a wide range of N-acylating moieties, including peptidyl, aminoacyl, benzoyl, benzyloxycarbonyl, folyl and pteroyl groups
This zinc enzyme is produced by pseudomonads, Flavobacterium sp. and Acinetobacter sp.
See also
Glutamate carboxypeptidase II
References
External links
EC 3.4.17 |
https://en.wikipedia.org/wiki/Carboxypeptidase%20C | Carboxypeptidase C (, carboxypeptidase Y, serine carboxypeptidase I, cathepsin A, lysosomal protective protein, deamidase, lysosomal carboxypeptidase A, phaseolin) is an enzyme. This enzyme catalyses the following chemical reaction
Release of a C-terminal amino acid with broad specificity
This enzyme is a carboxypeptidase with optimum activity at pH 4.5-6.0. It is inhibited by diisopropyl fluorophosphate.
See also
Cathepsin A
References
External links
EC 3.4.16 |
https://en.wikipedia.org/wiki/Cathepsin%20A | Cathepsin A is an enzyme that is classified both as a cathepsin and a carboxypeptidase. In humans, it is encoded by the CTSA gene.
Function
This gene encodes a glycoprotein that associates with lysosomal enzymes beta-galactosidase and neuraminidase to form a complex of high-molecular-weight multimers. The formation of this complex provides a protective role for stability and activity. It is protective for β-galactosidase and neuraminidase.
Clinical significance
Deficiencies in this gene are linked to multiple forms of galactosialidosis.
Interactions
Cathepsin A has been shown to interact with NEU1.
References
Further reading
External links
EC 3.4.16
Proteases
Cathepsins |
https://en.wikipedia.org/wiki/CIGL-FM | CIGL-FM is a Canadian radio station, broadcasting on the assigned frequency of 97.1 MHz in Belleville, Ontario, with the on-air branding of Mix 97. It airs a hot adult contemporary format.
History
The station first started in 1962 as CJBQ-FM, then changed its callsign to CIGL-FM in 1978. The former CJBQ callsign currently belongs to its sister station CJBQ. The call letters CIGL were often featured with seagulls in logos and advertisements, leading many to conclude that the call letters were a short form for "seagull".
Until 1995 CIGL featured essentially a "Beautiful Music" format playing many instrumental renditions of popular songs by artists such as Percy Faith, Nelson Riddle, Richard Clayderman, Frank Mills and Floyd Cramer. As the popularity of the Beautiful Music format decreased throughout the 1980s all around North America, more soft rock vocal music was added, including light songs by Kenny Rogers, Glenn Medieros and many others. On July 1, 1995, the station was re-branded as Mix 97, and adopted its current format.
CIGL is owned by Quinte Broadcasting.
On July 14, 2021, Quinte Broadcasting received CRTC approval to decrease the radiated power from 50,000 to 18,000 watts, increasing the effective antenna height above average terrain from 48.5 to 121 metres, and amending the existing coordinates of the transmitter site.
References
External links
Mix 97
Igl
Igl
Radio stations established in 1962
1962 establishments in Ontario |
https://en.wikipedia.org/wiki/Quasi-birth%E2%80%93death%20process | In queueing models, a discipline within the mathematical theory of probability, the quasi-birth–death process describes a generalisation of the birth–death process. As with the birth-death process it moves up and down between levels one at a time, but the time between these transitions can have a more complicated distribution encoded in the blocks.
Discrete time
The stochastic matrix describing the Markov chain has block structure
where each of A0, A1 and A2 are matrices and A*0, A*1 and A*2 are irregular matrices for the first and second levels.
Continuous time
The transition rate matrix for a quasi-birth-death process has a tridiagonal block structure
where each of B00, B01, B10, A0, A1 and A2 are matrices. The process can be viewed as a two dimensional chain where the block structure are called levels and the intra-block structure phases. When describing the process by both level and phase it is a continuous-time Markov chain, but when considering levels only it is a semi-Markov process (as transition times are then not exponentially distributed).
Usually the blocks have finitely many phases, but models like the Jackson network can be considered as quasi-birth-death processes with infinitely (but countably) many phases.
Stationary distribution
The stationary distribution of a quasi-birth-death process can be computed using the matrix geometric method.
References
Queueing theory
Markov processes |
https://en.wikipedia.org/wiki/Search-based%20software%20engineering | Search-based software engineering (SBSE) applies metaheuristic search techniques such as genetic algorithms, simulated annealing and tabu search to software engineering problems. Many activities in software engineering can be stated as optimization problems. Optimization techniques of operations research such as linear programming or dynamic programming are often impractical for large scale software engineering problems because of their computational complexity or their assumptions on the problem structure. Researchers and practitioners use metaheuristic search techniques, which impose little assumptions on the problem structure, to find near-optimal or "good-enough" solutions.
SBSE problems can be divided into two types:
black-box optimization problems, for example, assigning people to tasks (a typical combinatorial optimization problem).
white-box problems where operations on source code need to be considered.
Definition
SBSE converts a software engineering problem into a computational search problem that can be tackled with a metaheuristic. This involves defining a search space, or the set of possible solutions. This space is typically too large to be explored exhaustively, suggesting a metaheuristic approach. A metric (also called a fitness function, cost function, objective function or quality measure) is then used to measure the quality of potential solutions. Many software engineering problems can be reformulated as a computational search problem.
The term "searc |
https://en.wikipedia.org/wiki/Stephen%20Harvey%20%28biologist%29 | Stephen C. Harvey (born 1940) is a structural biologist with research interest in nucleic acids, the ribosome, virus structure and high density lipoprotein. He is currently an adjunct professor in the Department of Biochemistry and Biophysics at the University of Pennsylvania and professor emeritus and Georgia Research Alliance eminent scholar emeritus in the School of Biology at the Georgia Institute of Technology, Atlanta, Georgia. Harvey did his undergraduate work at the University of California (Berkeley), where he received his A.B. degree in physics. In the 1960s, he worked as a rocket test engineer on the Apollo program (the lunar mission project) and served with the Peace Corps in Colombia, before entering graduate school in physics at Dartmouth College, where he received his PhD in biophysics in 1971. Before moving to Georgia Tech in 2003, Harvey was professor in the Department of Biochemistry and Molecular Genetics at the University of Alabama at Birmingham (UAB).
He is past president of the Biophysical Society and co-author, with J. Andrew McCammon, of the classic book on Molecular Dynamics, Dynamics of Proteins and Nucleic Acids (Cambridge University Press, 1987; ). Harvey is married to the artist Marie Weaver. They live in Philadelphia, Pennsylvania.
The Marie Weaver and Steve Harvey Endowed Scholarship Fund for Graphic Design was set up in 2003 by the University of Alabama at Birmingham in honor of associate professor of graphic design Marie Weaver and her |
https://en.wikipedia.org/wiki/Nijenhuis%20bracket | In mathematics there are four different but related brackets named after Albert Nijenhuis, giving Lie superalgebra structures to various spaces of tensors:
Frölicher–Nijenhuis bracket (defined on vector valued forms, extending the Lie bracket of vector fields)
Nijenhuis–Richardson bracket (defined on vector valued forms; this has a different degree to the Frölicher-Nijenhuis bracket)
Schouten–Nijenhuis bracket (2 versions, defined on either symmetric or antisymmetric multivectors) |
https://en.wikipedia.org/wiki/List%20of%20British%20Rail%20power%20classifications | The British Transport Commission, later British Railways, used engine power output to categorise its requirements for the new main line diesel locomotive fleet following the 1955 modernisation plan. The locomotives built and put into service are listed below classified with the TOPS class numbers that were introduced in the early 1970s.
Type 1
Locomotives classed as Type 1 were of 1,000 bhp or below.
Class 14
Class 15
Class 16
Class 17
Class 20
Certain members of Class 21
Certain members of Class 22
Type 2
Locomotives classed as Type 2 produced between 1,001 bhp and 1,499 bhp.
Certain members of Class 21
Certain members of Class 22
Class 23
Class 24
Class 25
Class 26
Class 27
Class 28
Class 29
Class 30/31
Type 3
Locomotives classed as Type 3 produced between 1,500 bhp and 1,999 bhp.
Class 33/34
Class 35
Class 37
Type 4
Locomotives classed as Type 4 produced between 2,000 bhp and 2,999 bhp.
Class 40
Class 41
Class 42
Class 43 (Warship)
Class 43 (HST)
Class 44
Class 45
Class 46
Class 47
Class 48
Class 50
Class 52
Class 53
Class 57
D0260 Lion (prototype)
DP2 (prototype)
Type 5
Locomotives classed as Type 5 produced 3,000 bhp or more.
Class 55
Class 56
Class 58
Class 59
Class 60
Class 66
Class 67
Class 68
Class 70
References
List of types
British Rail Power Classifications |
https://en.wikipedia.org/wiki/Step%20Up%202%3A%20The%20Streets | Step Up 2: The Streets is a 2008 American dance drama film directed by Jon M. Chu (in his feature film directorial debut) and written by Toni Ann Johnson and Karen Barna. It serves as a sequel to 2006's Step Up and the second installment in the Step Up film series. The film stars Briana Evigan, Robert Hoffman, Will Kemp, and Cassie Ventura.
Set at the fictional Maryland School of the Arts, the story revolves around rebellious street dancer Andie West (Evigan) who lands at the elite school and finds herself fighting to fit in while also trying to hold onto her old life. She eventually joins forces with the school's hottest dancer Chase Collins (Hoffman) to form a crew of classmate outcasts to compete in Baltimore's underground dance battle The Streets, finding a way to live her dream while building a bridge between her two separate worlds.
Step Up 2: The Streets was released in the United States on February 14, 2008, by Walt Disney Studios Motion Pictures. Although the film received better reviews than its predecessor, it received mostly negative reviews from critics, but became a box office success, grossing $150.8 million worldwide against a budget of $17.5 million.
A sequel, Step Up 3D, was released on August 6, 2010, in the United States.
Plot
In Baltimore, Maryland, Andie West pursues her dream of becoming a street dancer, but feels like she does not belong anywhere. Her mother recently died of cancer, so she now lives with a guardian, her mother's best friend Sarah. |
https://en.wikipedia.org/wiki/Spectrum%20bias | In biostatistics, spectrum bias refers to the phenomenon that the performance of a diagnostic test may vary in different clinical settings because each setting has a different mix of patients. Because the performance may be dependent on the mix of patients, performance at one clinic may not be predictive of performance at another clinic. These differences are interpreted as a kind of bias. Mathematically, the spectrum bias is a sampling bias and not a traditional statistical bias; this has led some authors to refer to the phenomenon as spectrum effects, whilst others maintain it is a bias if the true performance of the test differs from that which is 'expected'. Usually the performance of a diagnostic test is measured in terms of its sensitivity and specificity and it is changes in these that are considered when referring to spectrum bias. However, other performance measures such as the likelihood ratios may also be affected by spectrum bias.
Generally spectrum bias is considered to have three causes. The first is due to a change in the case-mix of those patients with the target disorder (disease) and this affects the sensitivity. The second is due to a change in the case-mix of those without the target disorder (disease-free) and this affects the specificity. The third is due to a change in the prevalence, and this affects both the sensitivity and specificity. This final cause is not widely appreciated, but there is mounting empirical evidence as well as theoretical argume |
https://en.wikipedia.org/wiki/CJTN-FM | CJTN-FM is a radio station in Trenton, Ontario, broadcasting on the assigned frequency of 107.1 MHz, serving Belleville and the Quinte region. Owned by Quinte Broadcasting, the station airs a classic rock music format branded as Rock 107.
History
The station began broadcasting at 1270 kHz on January 22, 1979, at a power of 1,000 watts, to service Trenton; hence the TN in the call sign. Ted Snider was the station's first manager. The original AM transmitter was located at Carrying Place, just south of Trenton. CJTN moved to its current frequency at 107.1 FM on August 16, 2004, and was branded as Lite 107 with an adult contemporary format. The station changed to a classic rock format on May 18, 2007 and was re-branded as Rock 107.
CJTN's weekday line-up consists of The Morning Buzz with Buzz Collins featuring Tim Durkin with news and Jack Miller with sports. Rick Kevan hosts afternoons. Special feature shows include The House of Hair with Dee Snider on Friday nights, The Acoustic Storm with Jeff Parets on Saturday mornings, Flashback with Max Pinfield on Saturday nights and Sunday mornings and weekend afternoons with Greg Moulton and Scott Hunter. In August 2019, veteran announcer Rick Kevan celebrated 40 years with Quinte Broadcasting.
CJTN's transmitter is located near Wooler Road and Highway 401, northwest of Trenton. Its signal is directional, to avoid co-channel interference to the west with CILQ-FM in Toronto.
References
External links
Rock 107
CJTN History - Canadia |
https://en.wikipedia.org/wiki/Kevin%20McCurley%20%28cryptographer%29 | Kevin Snow McCurley is a mathematician, computer scientist, and cryptographer, and a former research scientist at Google. He has written publications about information retrieval, algorithms, parallel computing, cryptography, and number theory.
Early life and education
When he was a child, McCurley had built model planes and cars, and he enjoyed making things with his hands.
McCurley attended a high school in San Jose, California. There, one of his teachers, Judy Jones, showed him that "mathematics really could be fun and interesting" and encouraged him to attend mathematical contests.
In his first year at Santa Clara University, McCurley had Jerry Anderson, a former president of the MAA, as his professor in calculus; Anderson told "interesting stories" and was able to "relate the mathematics to history and to activities that were meaningful". He started out as a mathematician, but he later retrained himself as a computer scientist.
In 1981, McCurley received his Ph.D. in mathematics from the University of Illinois at Urbana-Champaign. His dissertation in analytic number theory was titled Explicit Estimates for Functions of Primes in Arithmetic Progressions, and his advisor was Paul Trevier Bateman. He also received a master's in statistics there.
In the fall of 1995, McCurley taught an undergraduate course on cryptology at the University of New Mexico.
After he was a post-doc at Michigan State University, McCurley took a job at USC (Los Angeles), where he published som |
https://en.wikipedia.org/wiki/MYO7A | Myosin VIIA is protein that in humans is encoded by the MYO7A gene. Myosin VIIA is a member of the unconventional myosin superfamily of proteins. Myosins are actin binding molecular motors that use the enzymatic conversion of ATP - ADP + inorganic phosphate (Pi) to provide the energy for movement.
Myosins are mechanochemical proteins characterized by the presence of a motor domain, an actin-binding domain, a neck domain that interacts with other proteins, and a tail domain that serves as an anchor. Myosin VIIA is an unconventional myosin with the longest tail (1360 aa). The tail is expected to dimerize, resulting in a two-headed molecule. Unconventional myosins have diverse functions in eukaryotic cells and are primarily thought to be involved in the movement or linkage of intra-cellular membranes and organelles to the actin cytoskeleton via interactions mediated by their highly divergent tail domains.
MYO7A is expressed in a number of mammalian tissues, including testis, kidney, lung, inner ear, retina and the ciliated epithelium of the nasal mucosa.
Clinical significance
Mutations in the MYO7A gene cause the Usher syndrome type 1B, a combined deafness/blindness disorder. Affected individuals are typically profoundly deaf at birth and then undergo progressive retinal degeneration.
Model organisms
Model organisms have been used in the study of MYO7A function. A spontaneous mutant mouse line, called Myo7ash1-6J was generated. Male and female animals underwent a standardi |
https://en.wikipedia.org/wiki/Environmental%20enterprise | An environmental enterprise is an environmentally friendly/compatible business. Specifically, an environmental enterprise is a business that produces value in the same manner which an ecosystem does, neither producing waste nor consuming unsustainable resources. In addition, an environmental enterprise rather finds alternative ways to produce one's products instead of taking advantage of animals for the sake of human profits. To be closer to the goal of being an environmentally friendly company, some environmental enterprises invest their money to develop or improve their technologies which are also environmentally friendly. In addition, environmental enterprises usually try to reduce global warming, so some companies use materials that are environmentally friendly to build their stores. They also set in place regulations that are environmentally friendly. All these efforts of the environmental enterprises can bring positive effects both for nature and people. The concept is rooted in the well-enumerated theories of natural capital, the eco-economy and cradle to cradle design. Examples of environmental enterprise would be Seventh Generation, Inc., and Whole Foods.
Background
Economic globalization is an irreversible trend
Natural resource scarcity or/and abundance are drivers of globalization, as they incite supply and demand forces in global markets.
Environment and sustainability
For the past 50 years we have amassed unprecedented financial wealth, but have also chronica |
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