source stringlengths 32 209 | text stringlengths 18 1.5k |
|---|---|
https://en.wikipedia.org/wiki/1%2C3-beta-galactosyl-N-acetylhexosamine%20phosphorylase | In enzymology, a 1,3-beta-galactosyl-N-acetylhexosamine phosphorylase () is an enzyme that catalyzes the chemical reaction
beta-D-galactopyranosyl-(1->3)-N-acetyl-D-glucosamine + phosphate alpha-D-galactopyranose 1-phosphate + N-acetyl-D-glucosamine
Thus, the two substrates of this enzyme are beta-D-galactopyranosyl-(1->3)-N-acetyl-D-glucosamine and phosphate, whereas its two products are alpha-D-galactopyranose 1-phosphate and N-acetyl-D-glucosamine.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is beta-D-galactopyranosyl-(1->3)-N-acetyl-D-hexosamine:phosphate galactosyltransferase.
References
Gene Ontology (GO) codes
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/1%2C3-beta-oligoglucan%20phosphorylase | In enzymology, a 1,3-beta-oligoglucan phosphorylase () is an enzyme that catalyzes the chemical reaction
(1,3-beta-D-glucosyl)n + phosphate (1,3-beta-D-glucosyl)n-1 + alpha-D-glucose 1-phosphate
Thus, the two substrates of this enzyme are (1,3-beta-D-glucosyl)n and phosphate, whereas its two products are (1,3-beta-D-glucosyl)n-1 and alpha-D-glucose 1-phosphate.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is 1,3-beta-D-oligoglucan:phosphate alpha-D-glucosyltransferase. Other names in common use include beta-1,3-oligoglucan:orthophosphate glucosyltransferase II, and beta-1,3-oligoglucan phosphorylase.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/13-hydroxydocosanoate%2013-beta-glucosyltransferase | In enzymology, a 13-hydroxydocosanoate 13-beta-glucosyltransferase () is an enzyme that catalyzes the chemical reaction. This reaction is part of biosynthesis. Extracts for research are frequently obtained from Candida yeasts.
UDP-glucose + 13-hydroxydocosanoate UDP + 13-beta-D-glucosyloxydocosanoate
Thus, the two substrates of this enzyme are UDP-glucose and 13-hydroxydocosanoate, whereas its two products are UDP and 13-beta-D-glucosyloxydocosanoate.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:13-hydroxydocosanoate 13-beta-D-glucosyltransferase. Other names in common use include 13-glucosyloxydocosanoate 2'-beta-glucosyltransferase, UDP-glucose:13-hydroxydocosanoic acid glucosyltransferase, uridine diphosphoglucose-hydroxydocosanoate glucosyltransferase, and UDP-glucose-13-hydroxydocosanoate glucosyltransferase.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/1%2C4-beta-D-xylan%20synthase | In enzymology, a 1,4-beta-D-xylan synthase () is an enzyme that catalyzes the chemical reaction
UDP-D-xylose + (1,4-beta-D-xylan)n UDP + (1,4-beta-D-xylan)n1
Thus, the two substrates of this enzyme are UDP-D-xylose and (1,4-beta-D-xylan)n, whereas its two products are UDP and (1,4-beta-D-xylan)n+1.
This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is UDP-D-xylose:1,4-beta-D-xylan 4-beta-D-xylosyltransferase. Other names in common use include uridine diphosphoxylose-1,4-beta-xylan xylosyltransferase, 1,4-beta-xylan synthase, xylan synthase, and xylan synthetase. This enzyme participates in starch and sucrose metabolism and nucleotide sugars metabolism.
References
EC 2.4.2
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/2%2C1-fructan%3A2%2C1-fructan%201-fructosyltransferase | In enzymology, a 2,1-fructan:2,1-fructan 1-fructosyltransferase () is an enzyme that catalyzes the chemical reaction
[beta-D-fructosyl-(2->1)-]m + [beta-D-fructosyl-(2->1)-]n [beta-D-fructosyl-(2->1)-]m-1 + [beta-D-fructosyl-(2->1)-]n+1
Thus, the two substrates of this enzyme are [[[beta-D-fructosyl-(2->1)-]]m]] and [[beta-D-fructosyl-(2->1)-]]n]], whereas its two products are [[beta-D-fructosyl-(2->1)-]]m-1]] and [[beta-D-fructosyl-(2->1)-]]n+1]].
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is 2,1-beta-D-fructan:2,1-beta-D-fructan 1-beta-D-fructosyltransferase. Other names in common use include 1,2-beta-D-fructan 1F-fructosyltransferase, fructan:fructan fructosyl transferase, FFT, 1,2-beta-fructan 1F-fructosyltransferase, 1,2-beta-D-fructan:1,2-beta-D-fructan, 1F-beta-D-fructosyltransferase, and fructan:fructan 1-fructosyl transferase.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/2-coumarate%20O-beta-glucosyltransferase | In enzymology, a 2-coumarate O-beta-glucosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-glucose + trans-2-hydroxycinnamate UDP + trans-beta-D-glucosyl-2-hydroxycinnamate
Thus, the two substrates of this enzyme are UDP-glucose and trans-2-hydroxycinnamate, whereas its two products are UDP and trans-beta-D-glucosyl-2-hydroxycinnamate.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:trans-2-hydroxycinnamate O-beta-D-glucosyltransferase. Other names in common use include uridine diphosphoglucose-o-coumarate glucosyltransferase, and UDPG:o-coumaric acid O-glucosyltransferase. This enzyme participates in phenylpropanoid biosynthesis.
References
EC 2.4.1
Enzymes of unknown structure
Hydroxycinnamic acids metabolism |
https://en.wikipedia.org/wiki/2-Hydroxyacylsphingosine%201-beta-galactosyltransferase | In enzymology, a 2-hydroxyacylsphingosine 1-beta-galactosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-galactose + 2-(2-hydroxyacyl)sphingosine UDP + 1-(beta-D-galactosyl)-2-(2-hydroxyacyl)sphingosine
Thus, the two substrates of this enzyme are UDP-galactose and 2-(2-hydroxyacyl)sphingosine, whereas its two products are UDP and 1-(beta-D-galactosyl)-2-(2-hydroxyacyl)sphingosine.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:2-(2-hydroxyacyl)sphingosine 1-beta-D-galactosyl-transferase. Other names in common use include galactoceramide synthase, uridine diphosphogalactose-2-hydroxyacylsphingosine, galactosyltransferase, UDPgalactose-2-hydroxyacylsphingosine galactosyltransferase, UDP-galactose:ceramide galactosyltransferase, and UDP-galactose:2-2-hydroxyacylsphingosine galactosyltransferase.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/3-Galactosyl-N-acetylglucosaminide%204-alpha-L-fucosyltransferase | In enzymology, a 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase () is an enzyme that catalyzes the chemical reaction
GDP-beta-L-fucose + beta-D-galactosyl-(1->3)-N-acetyl-D-glucosaminyl-R GDP + beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-N-acetyl-beta-D- glucosaminyl-R
Thus, the two substrates of this enzyme are GDP-beta-L-fucose and [[beta-D-galactosyl-(1->3)-N-acetyl-D-glucosaminyl-R]], whereas its 3 products are GDP, [[beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-N-acetyl-beta-D-]], and glucosaminyl-R.
This enzyme participates in 3 metabolic pathways: glycosphingolipid biosynthesis - lactoseries, glycosphingolipid biosynthesis - neo-lactoseries, and glycan structures - biosynthesis 2.
Nomenclature
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP-L-fucose:3-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 4I-alpha-L-fucosyltransferase. Other names in common use include:
(Lea)-dependent (alpha-3/4)-fucosyltransferase,
alpha(1,3/1,4) fucosyltransferase III,
alpha-(1->4)-L-fucosyltransferase,
alpha-4-L-fucosyltransferase,
beta-acetylglucosaminylsaccharide fucosyltransferase,
FucT-II,
Lewis alpha-(1->3/4)-fucosyltransferase,
Lewis blood group alpha-(1->3/4)-fucosyltransferase,
Lewis(Le) blood group gene-dependent,
alpha-(1->3/4)-L-fucosyltransferase,
blood group Lewis alpha-4-fucosyltransferase,
blood-group substance Lea-dependent fucosyltr |
https://en.wikipedia.org/wiki/4-galactosyl-N-acetylglucosaminide%203-alpha-L-fucosyltransferase | In enzymology, a 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase () is an enzyme that catalyzes the chemical reaction
GDP-beta-L-fucose + 1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R GDP + 1,4-beta-D-galactosyl-(alpha-1,3-L-fucosyl)-N-acetyl-D-glucosaminyl- R
Thus, the two substrates of this enzyme are GDP-beta-L-fucose and 1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R. Its 3 products are GDP, 1,4-beta-D-galactosyl-(alpha-1,3-L-fucosyl)-N-acetyl-D-glucosaminyl-, and R.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP-beta-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-alpha-L-fucosyltransferase. Other names in common use include:
Lewis-negative alpha-3-fucosyltransferase
plasma alpha-3-fucosyltransferase
guanosine diphosphofucose-glucoside alpha1→3-fucosyltransferase
galactoside 3-fucosyltransferase
GDP-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R
3-L-fucosyltransferase
GDP-beta-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R, and
3-L-fucosyltransferase
This enzyme participates in 3 metabolic pathways: glycosphingolipid biosynthesis - neo-lactoseries, glycosphingolipid biosynthesis - globoseries, and glycan structures - biosynthesis 2.
Structural studies
As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes , , and .
References
EC 2.4.1
Enzymes of known structure |
https://en.wikipedia.org/wiki/4-hydroxybenzoate%204-O-beta-D-glucosyltransferase | In enzymology, a 4-hydroxybenzoate 4-O-beta-D-glucosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-glucose + 4-hydroxybenzoate UDP + 4-(beta-D-glucosyloxy)benzoate
Thus, the two substrates of this enzyme are UDP-glucose and 4-hydroxybenzoate, whereas its two products are UDP and 4-(beta-D-glucosyloxy)benzoate.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:4-hydroxybenzoate 4-O-beta-D-glucosyltransferase. Other names in common use include uridine diphosphoglucose-4-hydroxybenzoate glucosyltransferase, UDP-glucose:4-(beta-D-glucopyranosyloxy)benzoic acid, glucosyltransferase, HBA glucosyltransferase, p-hydroxybenzoate glucosyltransferase, PHB glucosyltransferase, and PHB-O-glucosyltransferase.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/6G-fructosyltransferase | In enzymology, a 6G-fructosyltransferase () is an enzyme that catalyzes the chemical reaction
[1-beta-D-fructofuranosyl-(2->1)-]m+1 alpha-D-glucopyranoside + [1-beta-D-fructofuranosyl-(2->1)-]n+1 alpha-D-glucopyranoside [1-beta-D-fructofuranosyl-(2->1)-]m alpha-D-glucopyranoside + [1-beta-D-fructofuranosyl-(2->1)-]n+1 beta-D-fructofuranosyl-(2->6)-alpha-D-glucopyranoside (m > 0; n > 0)
Thus, the two substrates of this enzyme are [[[1-beta-D-fructofuranosyl-(2->1)-]m+1 alpha-D-glucopyranoside]] and [[[1-beta-D-fructofuranosyl-(2->1)-]n+1 alpha-D-glucopyranoside]], whereas its 4 products are [[[1-beta-D-fructofuranosyl-(2->1)-]m alpha-D-glucopyranoside]], [[[1-beta-D-fructofuranosyl-(2->1)-]n+1]], [[beta-D-fructofuranosyl-(2->6)-alpha-D-glucopyranoside (m > 0; n >=]], and 0.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is 1F-oligo[beta-D-fructofuranosyl-(2->1)-]sucrose 6G-beta-D-fructotransferase. Other names in common use include fructan:fructan 6G-fructosyltransferase, 1F(1-beta-D-fructofuranosyl)m, sucrose:1F(1-beta-D-fructofuranosyl)nsucrose, 6G-fructosyltransferase, 6G-FFT, 6G-FT, and 6G-fructotransferase.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Abequosyltransferase | In enzymology, an abequosyltransferase () is an enzyme that catalyzes the chemical reaction
CDP-abequose + D-mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid CDP + D-abequosyl-D-mannosyl-rhamnosyl-D-galactose-1-diphospholipid
Thus, the two substrates of this enzyme are CDP-abequose and D-mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid, whereas its two products are CDP and D-abequosyl-D-mannosyl-rhamnosyl-D-galactose-1-diphospholipid.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is CDP-abequose:D-mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid D-abequosyltransferase. This enzyme is also called trihexose diphospholipid abequosyltransferase.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Aldose%20beta-D-fructosyltransferase | In enzymology, an aldose beta-D-fructosyltransferase () is an enzyme that catalyzes the chemical reaction
alpha-D-aldosyl1 beta-D-fructoside + D-aldose2 D-aldose1 + alpha-D-aldosyl2 beta-D-fructoside
Thus, the two substrates of this enzyme are alpha-D-aldosyl1 beta-D-fructoside and D-aldose2, whereas its two products are D-aldose1 and alpha-D-aldosyl2 beta-D-fructoside.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is alpha-D-aldosyl-beta-D-fructoside:aldose 1-beta-D-fructosyltransferase.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Alginate%20synthase | In enzymology, an alginate synthase () is an enzyme that catalyzes the chemical reaction
GDP-D-mannuronate + (alginate)n GDP + (alginate)n+1
Thus, the two substrates of this enzyme are GDP-D-mannuronate and (alginate)n, whereas its two products are GDP and (alginate)n+1.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP-D-mannuronate:alginate D-mannuronyltransferase. This enzyme is also called mannuronosyl transferase. This enzyme participates in fructose and mannose metabolism.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Alizarin%202-beta-glucosyltransferase | In enzymology, an alizarin 2-beta-glucosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-glucose + alizarin UDP + 1-hydroxy-2-(beta-D-glucosyloxy)-9,10-anthraquinone
Thus, the two substrates of this enzyme are UDP-glucose and alizarin, whereas its two products are UDP and 1-hydroxy-2-(beta-D-glucosyloxy)-9,10-anthraquinone.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:1,2-dihydroxy-9,10-anthraquinone 2-O-beta-D-glucosyltransferase. This enzyme is also called uridine diphosphoglucose-alizarin glucosyltransferase.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Alpha-1%2C3-glucan%20synthase | In enzymology, an alpha-1,3-glucan synthase () is an enzyme that catalyzes the chemical reaction
UDP-glucose + [alpha-D-glucosyl-(1-3)]n UDP + [alpha-D-glucosyl-(1-3)]n+1
Thus, the two substrates of this enzyme are UDP-glucose and [[[alpha-D-glucosyl-(1-3)]n]], whereas its two products are UDP and [[[alpha-D-glucosyl-(1-3)]n+1]].
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:alpha-D-(1-3)-glucan 3-alpha-D-glucosyltransferase. Other names in common use include uridine diphosphoglucose-1,3-alpha-glucan glucosyltransferase, and 1,3-alpha-D-glucan synthase.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Alpha-1%2C4-glucan-protein%20synthase%20%28ADP-forming%29 | In enzymology, an alpha-1,4-glucan-protein synthase (ADP-forming) () is an enzyme that catalyzes the chemical reaction
ADP-glucose + protein ADP + alpha-D-glucosyl-protein
Thus, the two substrates of this enzyme are ADP-glucose and protein, whereas its two products are ADP and alpha-D-glucosyl-protein.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is ADP-glucose:protein 4-alpha-D-glucosyltransferase. Other names in common use include ADP-glucose:protein glucosyltransferase, and adenosine diphosphoglucose-protein glucosyltransferase.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Alpha%2Calpha-trehalose-phosphate%20synthase%20%28GDP-forming%29 | In enzymology, an alpha,alpha-trehalose-phosphate synthase (GDP-forming) () is an enzyme that catalyzes the chemical reaction
GDP-glucose + glucose 6-phosphate GDP + alpha,alpha-trehalose 6-phosphate
Thus, the two substrates of this enzyme are GDP-glucose and glucose 6-phosphate, whereas its two products are GDP and alpha,alpha'-trehalose 6-phosphate.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP-glucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase. Other names in common use include GDP-glucose-glucose-phosphate glucosyltransferase, guanosine diphosphoglucose-glucose phosphate glucosyltransferase, and trehalose phosphate synthase (GDP-forming).
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Alpha%2Calpha-trehalose-phosphate%20synthase%20%28UDP-forming%29 | In enzymology, an alpha,alpha-trehalose-phosphate synthase (UDP-forming) () is an enzyme that catalyzes the chemical reaction
UDP-glucose + D-glucose 6-phosphate UDP + alpha,alpha-trehalose 6-phosphate
Thus, the two substrates of this enzyme are UDP-glucose and D-glucose 6-phosphate, whereas its two products are UDP and alpha,alpha'-trehalose 6-phosphate.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase. Other names in common use include UDP-glucose-glucose-phosphate glucosyltransferase, trehalosephosphate-UDP glucosyltransferase, UDP-glucose-glucose-phosphate glucosyltransferase, alpha,alpha-trehalose phosphate synthase (UDP-forming), phosphotrehalose-uridine diphosphate transglucosylase, trehalose 6-phosphate synthase, trehalose 6-phosphate synthetase, trehalose phosphate synthase, trehalose phosphate synthetase, trehalose phosphate-uridine diphosphate glucosyltransferase, trehalose-P synthetase, transglucosylase, and uridine diphosphoglucose phosphate glucosyltransferase. This enzyme participates in starch and sucrose metabolism.
Structural studies
As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes , , and .
References
EC 2.4.1
Enzymes of known structure |
https://en.wikipedia.org/wiki/Alpha%2Calpha-trehalose%20phosphorylase | In enzymology, an alpha,alpha-trehalose phosphorylase () is an enzyme that catalyzes the chemical reaction
alpha,alpha-trehalose + phosphate D-glucose + beta-D-glucose 1-phosphate
Thus, the two substrates of this enzyme are trehalose and phosphate, whereas its two products are D-glucose and beta-D-glucose 1-phosphate.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is alpha,alpha-trehalose:phosphate beta-D-glucosyltransferase. This enzyme is also called trehalose phosphorylase. This enzyme participates in starch and sucrose metabolism.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Alpha%2Calpha-trehalose%20phosphorylase%20%28configuration-retaining%29 | In enzymology, an alpha,alpha-trehalose phosphorylase (configuration-retaining) () is an enzyme that catalyzes the chemical reaction
alpha,alpha-trehalose + phosphate alpha-D-glucose + alpha-D-glucose 1-phosphate
Thus, the two substrates of this enzyme are alpha,alpha-trehalose and phosphate, whereas its two products are alpha-D-glucose and alpha-D-glucose 1-phosphate.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is alpha,alpha-trehalose:phosphate alpha-D-glucosyltransferase. This enzyme is also called trehalose phosphorylase[ambiguous].
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Alpha-N-acetylgalactosaminide%20alpha-2%2C6-sialyltransferase | In enzymology, an alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase () is an enzyme that catalyzes the chemical reaction
CMP-N-acetylneuraminate + glycano-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein CMP + glycano-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)- glycoprotein
Thus, the two substrates of this enzyme are CMP-N-acetylneuraminate and glycano-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein, whereas its 3 products are CMP, glycano-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-, and glycoprotein.
This enzyme belongs to the family of transferases, specifically those glycosyltransferases that do not transfer hexosyl or pentosyl groups. The systematic name of this enzyme class is CMP-N-acetylneuraminate:glycano-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein alpha-2,6-N-acetylneuraminyltransferase. This enzyme participates in o-glycan biosynthesis and glycan structures - biosynthesis 1.
References
EC 2.4.99
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Alpha-N-acetylneuraminate%20alpha-2%2C8-sialyltransferase | In enzymology, an alpha-N-acetylneuraminate alpha-2,8-sialyltransferase () is an enzyme that catalyzes the chemical reaction
CMP-N-acetylneuraminate + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-R CMP + alpha-N-acetylneuraminyl-2,8-alpha-N-acetylneuraminyl-2,3-beta-D- galactosyl-R
Thus, the two substrates of this enzyme are CMP-N-acetylneuraminate and alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-R, whereas its 3 products are CMP, alpha-N-acetylneuraminyl-2,8-alpha-N-acetylneuraminyl-2,3-beta-D-, and galactosyl-R. This enzyme participates in 4 metabolic pathways: glycosphingolipid biosynthesis - neo-lactoseries, glycosphingolipid biosynthesis - globoseries, glycosphingolipid biosynthesis - ganglioseries, and glycan structures - biosynthesis 2.
This enzyme belongs to the family of transferases, specifically those glycosyltransferases that do not transfer hexosyl or pentosyl groups. The systematic name of this enzyme class is CMP-N-acetylneuraminate:alpha-N-acetylneuraminyl-2,3-beta-D-galactos ide alpha-2,8-N-acetylneuraminyltransferase. Other names in common use include cytidine monophosphoacetylneuraminate-ganglioside GM3, alpha-2,8-sialyltransferase, ganglioside GD3 synthase, ganglioside GD3 synthetase sialyltransferase, CMP-NeuAc:LM1(alpha2-8) sialyltransferase, GD3 synthase, and SAT-2.
References
EC 2.4.99
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Amylosucrase | In enzymology, an amylosucrase () is an enzyme that catalyzes the chemical reaction
sucrose + (1,4-alpha-D-glucosyl)n D-fructose + (1,4-alpha-D-glucosyl)n+1
Thus, the two substrates of this enzyme are sucrose and (1,4-alpha-D-glucosyl)n, whereas its two products are D-fructose and (1,4-alpha-D-glucosyl)n+1.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is sucrose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase. Other names in common use include sucrose-glucan glucosyltransferase, and sucrose-1,4-alpha-glucan glucosyltransferase. This enzyme participates in starch and sucrose metabolism.
Structural studies
As of late 2007, 10 structures have been solved for this class of enzymes, with PDB accession codes , , , , , , , , , and .
References
EC 2.4.1
Enzymes of known structure |
https://en.wikipedia.org/wiki/Anthocyanidin%203-O-glucosyltransferase | In enzymology, an anthocyanidin 3-O-glucosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-D-glucose + an anthocyanidin UDP + an anthocyanidin-3-O-beta-D-glucoside
Thus, the two substrates of this enzyme are UDP-D-glucose and anthocyanidin, whereas its two products are UDP and anthocyanidin-3-O-beta-D-glucoside.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-D-glucose:anthocyanidin 3-O-beta-D-glucosyltransferase. Other names in common use include uridine diphosphoglucose-anthocyanidin 3-O-glucosyltransferase, UDP-glucose:anthocyanidin/flavonol 3-O-glucosyltransferase, UDP-glucose:cyanidin-3-O-glucosyltransferase, UDP-glucose:anthocyanidin 3-O-D-glucosyltransferase, and 3-GT. This enzyme participates in flavonoid biosynthesis.
References
EC 2.4.1
Enzymes of unknown structure
Anthocyanins metabolism |
https://en.wikipedia.org/wiki/Anthocyanin%203%27-O-beta-glucosyltransferase | In enzymology, an anthocyanin 3'-O-beta-glucosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-glucose + an anthocyanin UDP + an anthocyanin 3'-O-beta-D-glucoside
Thus, the two substrates of this enzyme are UDP-glucose and anthocyanin, whereas its two products are UDP and anthocyanin 3'-O-beta-D-glucoside.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:anthocyanin 3'-O-beta-D-glucosyltransferase. Other names in common use include UDP-glucose:anthocyanin 3'-O-glucosyltransferase, and 3'GT.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Anthranilate%20phosphoribosyltransferase | In enzymology, an anthranilate phosphoribosyltransferase () is an enzyme that catalyzes the chemical reaction
anthranilate + phosphoribosyl pyrophosphate N-(5-phosphoribosyl)-anthranilate + diphosphate
The two substrates of this enzyme are anthranilate and phosphoribosyl pyrophosphate. Its two products are N-(5-phosphoribosyl)-anthranilate and diphosphate.
This enzyme participates in aromatic amino acid biosynthesis and two-component system (general).
Nomenclature
This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is N-(5-phospho-D-ribosyl)-anthranilate:diphosphate phospho-alpha-D-ribosyltransferase.
Other names in common use are:
anthranilate 5-phosphoribosylpyrophosphate
anthranilate phosphoribosylpyrophosphate phosphoribosyltransferase
anthranilate-PP-ribose-P phosphoribosyltransferase
phosphoribosyl-anthranilate pyrophosphorylase
phosphoribosylanthranilate pyrophosphorylase
phosphoribosylanthranilate transferase
phosphoribosyltransferase
PRT
Function
Anthranilate phosphoribosyltransferase (AnPRT) is a transferase enzyme which catalyses one of the most fundamental biochemical reactions: the transfer of a ribose group between an aromatic base and phosphate groups. More specifically, AnPRT facilitates the formation of a carbon-nitrogen bond between 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) and anthranilate.
Reaction
In the aromatic amino acid biosynthesis pathway |
https://en.wikipedia.org/wiki/Arylamine%20glucosyltransferase | In enzymology, an arylamine glucosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-glucose + an arylamine UDP + an N-D-glucosylarylamine
Thus, the two substrates of this enzyme are UDP-glucose and arylamine, whereas its two products are UDP and N-D-glucosylarylamine.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:arylamine N-D-glucosyltransferase. Other names in common use include UDP glucose-arylamine glucosyltransferase, and uridine diphosphoglucose-arylamine glucosyltransferase.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/ATP%20phosphoribosyltransferase | In enzymology, an ATP phosphoribosyltransferase () is an enzyme that catalyzes the chemical reaction
1-(5-phospho-D-ribosyl)-ATP + diphosphate ATP + 5-phospho-alpha-D-ribose 1-diphosphate
Thus, the two substrates of this enzyme are 1-(5-phospho-D-ribosyl)-ATP and diphosphate, whereas its two products are ATP and 5-phospho-alpha-D-ribose 1-diphosphate.
This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is 1-(5-phospho-D-ribosyl)-ATP:diphosphate phospho-alpha-D-ribosyl-transferase. Other names in common use include phosphoribosyl-ATP pyrophosphorylase, adenosine triphosphate phosphoribosyltransferase, phosphoribosyladenosine triphosphate:pyrophosphate, phosphoribosyltransferase, phosphoribosyl ATP synthetase, phosphoribosyl ATP:pyrophosphate phosphoribosyltransferase, phosphoribosyl-ATP:pyrophosphate-phosphoribosyl phosphotransferase, phosphoribosyladenosine triphosphate pyrophosphorylase, and phosphoribosyladenosine triphosphate synthetase.
This enzyme catalyses the first step in the biosynthesis of histidine in bacteria, fungi and plants. It is a member of the larger phosphoribosyltransferase superfamily of enzymes which catalyse the condensation of 5-phospho-alpha-D-ribose 1-diphosphate with nitrogenous bases in the presence of divalent metal ions.
Histidine biosynthesis is an energetically expensive process and ATP phosphoribosyltransferase activity is subject to control at severa |
https://en.wikipedia.org/wiki/Beta-galactoside%20alpha-2%2C3-sialyltransferase | In enzymology, a beta-galactoside alpha-2,3-sialyltransferase () is an enzyme that catalyzes the chemical reaction
CMP-N-acetylneuraminate + beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-alpha-D- galactosaminyl-R
Thus, the two substrates of this enzyme are CMP-N-acetylneuraminate and beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R, whereas its 3 products are CMP, alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-alpha-D-, and galactosaminyl-R.
This enzyme belongs to the family of transferases, specifically those glycosyltransferases that do not transfer hexosyl or pentosyl groups. The systematic name of this enzyme class is CMP-N-acetylneuraminate:beta-D-galactoside alpha-2,3-N-acetylneuraminyl-transferase. This enzyme participates in 7 metabolic pathways: o-glycan biosynthesis, keratan sulfate biosynthesis, glycosphingolipid biosynthesis - lactoseries, glycosphingolipid biosynthesis - globoseries, glycosphingolipid biosynthesis - ganglioseries, glycan structures - biosynthesis 1, and glycan structures - biosynthesis 2.
Structural studies
As of late 2007, 9 structures have been solved for this class of enzymes, with PDB accession codes , , , , , , , , and .
References
EC 2.4.99
Enzymes of known structure |
https://en.wikipedia.org/wiki/Beta-galactoside%20alpha-2%2C6-sialyltransferase | In enzymology, a beta-galactoside alpha-2,6-sialyltransferase () is an enzyme that catalyzes the chemical reaction
CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine CMP + alpha-N-acetylneuraminyl-2,6-beta-D-galactosyl-1,4-N-acetyl-beta-D- glucosamine
Thus, the two substrates of this enzyme are CMP-N-acetylneuraminate and beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine, whereas its three products are CMP, alpha-N-acetylneuraminyl-2,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-, and glucosamine.
This enzyme belongs to the family of transferases, specifically those glycosyltransferases that do not transfer hexosyl or pentosyl groups. The systematic name of this enzyme class is CMP-N-acetylneuraminate:beta-D-galactosyl-1,4-N-acetyl-beta-D-glucos amine alpha-2,6-N-acetylneuraminyltransferase. This enzyme participates in n-glycan biosynthesis and glycan structures - biosynthesis 1.
References
EC 2.4.99
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Bilirubin-glucuronoside%20glucuronosyltransferase | In enzymology, a bilirubin-glucuronoside glucuronosyltransferase () is an enzyme that catalyzes the chemical reaction
2 bilirubin-glucuronoside bilirubin + bilirubin-bisglucuronoside
Hence, this enzyme has one substrate, bilirubin-glucuronoside, and two products, bilirubin and bilirubin-bisglucuronoside.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is bilirubin-glucuronoside:bilirubin-glucuronoside D-glucuronosyltransferase. Other names in common use include bilirubin monoglucuronide transglucuronidase, and bilirubin glucuronoside glucuronosyltransferase.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Cellobiose%20phosphorylase | In enzymology, a cellobiose phosphorylase () is an enzyme that catalyzes the chemical reaction
cellobiose + phosphate alpha-D-glucose 1-phosphate + D-glucose
Thus, the two substrates of this enzyme are cellobiose and phosphate, whereas its two products are alpha-D-glucose 1-phosphate and D-glucose.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is cellobiose:phosphate alpha-D-glucosyltransferase. This enzyme participates in starch and sucrose metabolism.
Structural studies
As of late 2006, two structures have been solved for this class of enzymes, with PDB accession codes and .
References
EC 2.4.1
Enzymes of known structure |
https://en.wikipedia.org/wiki/Cellodextrin%20phosphorylase | In enzymology, a cellodextrin phosphorylase () is an enzyme that catalyzes the chemical reaction
(1,4-beta-D-glucosyl)n + phosphate (1,4-beta-D-glucosyl)n-1 + alpha-D-glucose 1-phosphate
Thus, the two substrates of this enzyme are (1,4-beta-D-glucosyl)n and phosphate, whereas its two products are (1,4-beta-D-glucosyl)n-1 and alpha-D-glucose 1-phosphate.
This enzyme belongs to GH (glycoside hydrolases) family 94. The systematic name of this enzyme class is 1,4-beta-D-oligo-D-glucan:phosphate alpha-D-glucosyltransferase. This enzyme is also called beta-1,4-oligoglucan:orthophosphate glucosyltransferase.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Cellulose%20synthase%20%28GDP-forming%29 | In enzymology, a cellulose synthase (GDP-forming) () is an enzyme that catalyzes the chemical reaction
GDP-glucose + (1,4-beta-D-glucosyl)n GDP + (1,4-beta-D-glucosyl)n+1
Thus, the two substrates of this enzyme are GDP-glucose and (1,4-beta-D-glucosyl)n, whereas its two products are GDP and (1,4-beta-D-glucosyl)n+1.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP-glucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase. Other names in common use include cellulose synthase (guanosine diphosphate-forming), cellulose synthetase, guanosine diphosphoglucose-1,4-beta-glucan glucosyltransferase, and guanosine diphosphoglucose-cellulose glucosyltransferase. This enzyme participates in starch and sucrose metabolism.
, no proteins with this activity are known in the UniProt/NiceZYme or the gene ontology database.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Cellulose%20synthase%20%28UDP-forming%29 | The UDP-forming form of cellulose synthase () is the main enzyme that produces cellulose. Systematically, it is known as UDP-glucose:(1→4)-β-D-glucan 4-β-D-glucosyltransferase in enzymology. It catalyzes the chemical reaction:
UDP-glucose + [(1→4)-β-D-glucosyl]n = UDP + [(1→4)-β-D-glucosyl]n+1
A similar enzyme utilizes GDP-glucose, cellulose synthase (GDP-forming) (EC 2.4.1.29).
This family of enzymes is found in bacteria and plants alike. Plant members are usually known as CesA (cellulose synthase) or the tentative CslA (cellulose synthase-like), while bacterial members may additionally be known as BcsA (bacterial cellulose synthase) or CelA (simply "cellulose"). Plants acquired CesA from the endosymbiosis event that produced the chloroplast. This family belongs to glucosyltransferase family 2 (GT2). Glycosyltransferases are involved in the biosynthesis and hydrolysis of the bulk of earth's biomass. There are known to be about seven subfamilies in the plant CesA superfamily, or ten in the combined plant-algal superfamily. Urochordates are the only group of animals possessing this enzyme, having acquired them by horizontal gene transfer more than 530 million years ago.
Cellulose
Cellulose is an aggregation of unbranched polymer chains made of β-(1→4)-linked glucose residues that makes up a large portion of primary and secondary cell walls. Although important for plants, it is also synthesized by most algae, some bacteria, and some animals. Worldwide, 2 × 1011 tons of |
https://en.wikipedia.org/wiki/Chitin%20synthase | In enzymology, a chitin synthase () is an enzyme that catalyzes the chemical reaction
UDP-N-acetyl-D-glucosamine + [1,4-(N-acetyl-beta-D-glucosaminyl)]n UDP + [1,4-(N-acetyl-beta-D-glucosaminyl)]n+1
Thus, the two substrates of this enzyme are UDP-N-acetyl-D-glucosamine and [[[1,4-(N-acetyl-beta-D-glucosaminyl)]n]], whereas its two products are UDP and [[[1,4-(N-acetyl-beta-D-glucosaminyl)]n+1]].
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase. Other names in common use include chitin-UDP N-acetylglucosaminyltransferase, chitin-uridine diphosphate acetylglucosaminyltransferase, chitin synthetase, and trans-N-acetylglucosaminosylase. This enzyme participates in aminosugars metabolism.
Production
Chitin Synthase is manufactured in the rough endoplasmic reticulum of fungi as the inactive form, zymogen. The zymogen is then packaged into chitosomes in the golgi apparatus. Chitosomes bring the zymogen to the hyphal tip of a mold or yeast cell membrane. Chitin synthase is placed into the interior side of the cell membrane and then activated.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Chitobiosyldiphosphodolichol%20beta-mannosyltransferase | In enzymology, a chitobiosyldiphosphodolichol beta-mannosyltransferase () is an enzyme that catalyzes the chemical reaction
GDP-mannose + chitobiosyldiphosphodolichol GDP + beta-1,4-D-mannosylchitobiosyldiphosphodolichol
Thus, the two substrates of this enzyme are GDP-mannose and chitobiosyldiphosphodolichol, whereas its two products are GDP and beta-1,4-D-mannosylchitobiosyldiphosphodolichol.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP-mannose:chitobiosyldiphosphodolichol beta-D-mannosyltransferase. Other names in common use include guanosine diphosphomannose-dolichol diphosphochitobiose, mannosyltransferase, and GDP-mannose-dolichol diphosphochitobiose mannosyltransferase. This enzyme participates in n-glycan biosynthesis and glycan structures - biosynthesis 1.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Cinnamate%20beta-D-glucosyltransferase | In enzymology, a cinnamate beta-D-glucosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-glucose + trans-cinnamate UDP + trans-cinnamoyl beta-D-glucoside
Thus, the two substrates of this enzyme are UDP-glucose and trans-cinnamate, whereas its two products are UDP and trans-cinnamoyl beta-D-glucoside.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:trans-cinnamate beta-D-glucosyltransferase. Other names in common use include uridine diphosphoglucose-cinnamate glucosyltransferase, and UDPG:t-cinnamate glucosyltransferase.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Cis-p-Coumarate%20glucosyltransferase | In enzymology, a cis-p-Coumarate glucosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-glucose + cis-p-Coumarate 4'-O-beta-D-glucosyl-cis-p-coumarate + UDP
Thus, the two substrates of this enzyme are UDP-glucose and cis-p-coumarate, whereas its two products are 4'-O-beta-D-glucosyl-cis-p-coumarate and UDP.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:cis-p-coumarate beta-D-glucosyltransferase.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Cis-zeatin%20O-beta-D-glucosyltransferase | In enzymology, a cis-zeatin O-beta-D-glucosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-glucose + cis-zeatin UDP + O-beta-D-glucosyl-cis-zeatin
Thus, the two substrates of this enzyme are UDP-glucose and cis-zeatin, whereas its two products are UDP and O-beta-D-glucosyl-cis-zeatin.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:cis-zeatin O-beta-D-glucosyltransferase.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Coniferyl-alcohol%20glucosyltransferase | In enzymology, a coniferyl-alcohol glucosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-glucose + coniferyl alcohol UDP + coniferin
Thus, the two substrates of this enzyme are UDP-glucose and coniferyl alcohol, whereas its two products are UDP and coniferin.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:coniferyl-alcohol 4'-beta-D-glucosyltransferase. Other names in common use include uridine diphosphoglucose-coniferyl alcohol glucosyltransferase, and UDP-glucose coniferyl alcohol glucosyltransferase. This enzyme participates in phenylpropanoid biosynthesis.
References
EC 2.4.1
Enzymes of unknown structure
Phenylpropanoids metabolism |
https://en.wikipedia.org/wiki/Cyanidin%203-O-rutinoside%205-O-glucosyltransferase | In enzymology, a cyanidin 3-O-rutinoside 5-O-glucosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-glucose + cyanidin 3-O-rutinoside UDP + cyanidin 3-O-rutinoside 5-O-beta-D-glucoside
Thus, the two substrates of this enzyme are UDP-glucose and cyanidin 3-O-rutinoside, whereas its two products are UDP and cyanidin 3-O-rutinoside 5-O-beta-D-glucoside.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:cyanidin-3-O-beta-L-rhamnosyl-(1->6)-beta-D-glucoside 5-O-beta-D-glucosyltransferase. Other names in common use include uridine diphosphoglucose-cyanidin 3-rhamnosylglucoside, 5-O-glucosyltransferase, cyanidin-3-rhamnosylglucoside 5-O-glucosyltransferase, UDP-glucose:cyanidin-3-O-D-rhamnosyl-1,6-D-glucoside, and 5-O-D-glucosyltransferase.
See also
Cyanidin
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Cyanohydrin%20beta-glucosyltransferase | In enzymology, a cyanohydrin beta-glucosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-D-glucose + (S)-4-hydroxymandelonitrile UDP + (S)-4-hydroxymandelonitrile beta-D-glucoside
Thus, the two substrates of this enzyme are UDP-D-glucose and (S)-4-hydroxymandelonitrile, whereas its two products are UDP and (S)-4-hydroxymandelonitrile beta-D-glucoside.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-D-glucose:(S)-4-hydroxymandelonitrile beta-D-glucosyltransferase. Other names in common use include uridine diphosphoglucose-p-hydroxymandelonitrile, glucosyltransferase, UDP-glucose-p-hydroxymandelonitrile glucosyltransferase, uridine diphosphoglucose-cyanohydrin glucosyltransferase, uridine diphosphoglucose:aldehyde cyanohydrin, beta-glucosyltransferase, UDP-glucose:(S)-4-hydroxymandelonitrile beta-D-glucosyltransferase, UGT85B1, and UDP-glucose:p-hydroxymandelonitrile-O-glucosyltransferase. This enzyme participates in tyrosine metabolism and cyanoamino acid metabolism.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Cytokinin%207-beta-glucosyltransferase | In enzymology, a cytokinin 7-β-glucosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-glucose + N6-alkylaminopurine UDP + N6-alkylaminopurine-7-β-D-glucoside
Thus, the two substrates of this enzyme are UDP-glucose and N6-alkylaminopurine, whereas its two products are UDP and N6-alkylaminopurine-7-β-D-glucoside.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:N6-alkylaminopurine 7-glucosyltransferase. Other names in common use include uridine diphosphoglucose-zeatin 7-glucosyltransferase, and cytokinin 7-glucosyltransferase.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Deoxyuridine%20phosphorylase | In enzymology, a deoxyuridine phosphorylase is an enzyme that catalyzes the chemical reaction
2'-deoxyuridine + phosphate uracil + 2-deoxy-alpha-D-ribose 1-phosphate
Thus, the two substrates of this enzyme are 2'-deoxyuridine and phosphate, whereas its two products are uracil and 2-deoxy-alpha-D-ribose 1-phosphate.
No enzyme is known to be specific for this reaction, hence the EC number originally assigned to this enzyme function (EC 2.4.2.23) was deleted by the IUBMB in 2013. The reaction is catalysed by , pyrimidine-nucleoside phosphorylase, , uridine phosphorylase, and , thymidine phosphorylase.
These enzymes belong to the family of glycosyltransferases, specifically the pentosyltransferases. They participate in pyrimidine metabolism.
References
Enzymes of unknown structure
EC 2.4.2 |
https://en.wikipedia.org/wiki/Dextransucrase | In enzymology, a dextransucrase () is an enzyme that catalyzes the chemical reaction
sucrose + (1,6-alpha-D-glucosyl)n D-fructose + (1,6-alpha-D-glucosyl)n+1
Thus, the two substrates of this enzyme are sucrose and (1,6-alpha-D-glucosyl)n, whereas its two products are D-fructose and (1,6-alpha-D-glucosyl)n+1.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is sucrose:1,6-alpha-D-glucan 6-alpha-D-glucosyltransferase. Other names in common use include sucrose 6-glucosyltransferase, SGE, CEP, and sucrose-1,6-alpha-glucan glucosyltransferase. This enzyme participates in starch and sucrose metabolism and two-component system - general.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Dextrin%20dextranase | In enzymology, a dextrin dextranase () is an enzyme that catalyzes the chemical reaction
(1,4-alpha-D-glucosyl)n + (1,6-alpha-D-glucosyl)m (1,4-alpha-D-glucosyl)n-1 + (1,6-alpha-D-glucosyl)m+1
Thus, the two substrates of this enzyme are (1,4-alpha-D-glucosyl)n and (1,6-alpha-D-glucosyl)m, whereas its two products are (1,4-alpha-D-glucosyl)n-1 and (1,6-alpha-D-glucosyl)m+1.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is 1,4-alpha-D-glucan:1,6-alpha-D-glucan 6-alpha-D-glucosyltransferase. Other names in common use include dextrin 6-glucosyltransferase, and dextran dextrinase.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Digalactosyldiacylglycerol%20synthase | In enzymology, a digalactosyldiacylglycerol synthase () is an enzyme that catalyzes the chemical reaction
UDP-galactose + 3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol UDP + 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-diacyl-sn- glycerol
Thus, the two substrates of this enzyme are UDP-galactose and 3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol, whereas its 3 products are UDP, [[3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-diacyl-sn-]], and glycerol.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol 6-alpha-galactosyltransferase. Other names in common use include DGD1, DGD2, DGDG synthase (ambiguous), UDP-galactose-dependent DGDG synthase, UDP-galactose-dependent digalactosyldiacylglycerol synthase, and UDP-galactose:MGDG galactosyltransferase. This enzyme participates in glycerolipid metabolism.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Diglucosyl%20diacylglycerol%20synthase | In enzymology, a diglucosyl diacylglycerol synthase () is an enzyme that catalyzes the chemical reaction
UDP-glucose + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol 1,2-diacyl-3-O-(alpha-D-glucopyranosyl(1->2)-O-alpha-D- glucopyranosyl)sn-glycerol + UDP
Thus, the two substrates of this enzyme are UDP-glucose and 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol, whereas its 2 products are 1,2-diacyl-3-O-(alpha-D-glucopyranosyl(1-2)-O-alpha-D-glucopyranosyl)sn-glycerol, and UDP.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol (1->2) glucosyltransferase. Other names in common use include monoglucosyl diacylglycerol (1->2) glucosyltransferase, MGlcDAG (1->2) glucosyltransferase, and DGlcDAG synthase. It employs one cofactor, magnesium.
References
EC 2.4.1
Magnesium enzymes
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Dioxotetrahydropyrimidine%20phosphoribosyltransferase | In enzymology, a dioxotetrahydropyrimidine phosphoribosyltransferase () is an enzyme that catalyzes the chemical reaction
a 2,4-dioxotetrahydropyrimidine D-ribonucleotide + diphosphate a 2,4-dioxotetrahydropyrimidine + 5-phospho-alpha-D-ribose 1-diphosphate
Thus, the two substrates of this enzyme are 2,4-dioxotetrahydropyrimidine D-ribonucleotide and diphosphate, whereas its two products are 2,4-dioxotetrahydropyrimidine and 5-phospho-alpha-D-ribose 1-diphosphate.
This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is 2,4-dioxotetrahydropyrimidine-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase. Other names in common use include dioxotetrahydropyrimidine-ribonucleotide pyrophosphorylase, dioxotetrahydropyrimidine phosphoribosyl transferase, and dioxotetrahydropyrimidine ribonucleotide pyrophosphorylase.
References
EC 2.4.2
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Dolichyl-diphosphooligosaccharide%E2%80%93protein%20glycotransferase | In enzymology, a dolichyl-diphosphooligosaccharide–protein glycotransferase () is an enzyme that catalyzes the chemical reaction
dolichyl diphosphooligosaccharide + protein L-asparagine dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by N-glycosyl linkage to protein L-asparagine
Thus, the two substrates of this enzyme are dolichyl diphosphooligosaccharide and protein L-asparagine, whereas its 3 products are dolichyl diphosphate, glycoprotein with the oligosaccharide chain attached by N-glycosyl, and linkage to protein L-asparagine.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is dolichyl-diphosphooligosaccharide:protein-L-asparagine oligopolysaccharidotransferase. Other names in common use include dolichyldiphosphooligosaccharide-protein glycosyltransferase, asparagine N-glycosyltransferase, dolichyldiphosphooligosaccharide-protein oligosaccharyltransferase, dolichylpyrophosphodiacetylchitobiose-protein glycosyltransferase, oligomannosyltransferase, oligosaccharide transferase, dolichyldiphosphoryloligosaccharide-protein, and oligosaccharyltransferase. This enzyme participates in n-glycan biosynthesis and glycan structures - biosynthesis 1.
References
EC 2.4.99
Enzymes of known structure |
https://en.wikipedia.org/wiki/Dolichyl-phosphate%20alpha-N-acetylglucosaminyltransferase | In enzymology, a dolichyl-phosphate alpha-N-acetylglucosaminyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-N-acetyl-D-glucosamine + dolichyl phosphate UDP + dolichyl N-acetyl-alpha-D-glucosaminyl phosphate
Thus, the two substrates of this enzyme are UDP-N-acetyl-D-glucosamine and dolichyl phosphate, whereas its two products are UDP and dolichyl N-acetyl-alpha-D-glucosaminyl phosphate.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-N-acetyl-D-glucosamine:dolichyl-phosphate alpha-N-acetyl-D-glucosaminyltransferase. Other names in common use include uridine diphosphoacetylglucosamine-dolichol phosphate, acetylglucosaminyltransferase, dolichyl phosphate acetylglucosaminyltransferase, dolichyl phosphate N-acetylglucosaminyltransferase, UDP-N-acetylglucosamine-dolichol phosphate, and N-acetylglucosaminyltransferase.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Dolichyl-phosphate%20beta-D-mannosyltransferase | In enzymology, a dolichyl-phosphate beta-D-mannosyltransferase () is an enzyme that catalyzes the chemical reaction
GDP-mannose + dolichyl phosphate GDP + dolichyl D-mannosyl phosphate
Thus, the two substrates of this enzyme are GDP-mannose and dolichyl phosphate, whereas its two products are GDP and dolichyl D-mannosyl phosphate.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP-mannose:dolichyl-phosphate beta-D-mannosyltransferase. Other names in common use include GDP-Man:DolP mannosyltransferase, dolichyl mannosyl phosphate synthase, dolichyl-phospho-mannose synthase, GDP-mannose:dolichyl-phosphate mannosyltransferase, guanosine diphosphomannose-dolichol phosphate mannosyltransferase, dolichol phosphate mannose synthase, dolichyl phosphate mannosyltransferase, dolichyl-phosphate mannose synthase, GDP-mannose-dolichol phosphate mannosyltransferase, GDP-mannose-dolichylmonophosphate mannosyltransferase, mannosylphosphodolichol synthase, and mannosylphosphoryldolichol synthase. This enzyme participates in n-glycan biosynthesis.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Dolichyl-phosphate%20beta-glucosyltransferase | In enzymology, a dolichyl-phosphate beta-glucosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-glucose + dolichyl phosphate UDP + dolichyl beta-D-glucosyl phosphate
Thus, the two substrates of this enzyme are UDP-glucose and dolichyl phosphate, whereas its two products are UDP and dolichyl beta-D-glucosyl phosphate.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:dolichyl-phosphate beta-D-glucosyltransferase. Other names in common use include polyprenyl phosphate:UDP-D-glucose glucosyltransferase, UDP-glucose dolichyl-phosphate glucosyltransferase, uridine diphosphoglucose-dolichol glucosyltransferase, UDP-glucose:dolichol phosphate glucosyltransferase, UDP-glucose:dolicholphosphoryl glucosyltransferase, UDP-glucose:dolichyl monophosphate glucosyltransferase, and UDP-glucose:dolichyl phosphate glucosyltransferase. This enzyme participates in n-glycan biosynthesis.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Dolichyl-phosphate%20D-xylosyltransferase | In enzymology, a dolichyl-phosphate D-xylosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-D-xylose + dolichyl phosphate UDP + dolichyl D-xylosyl phosphate
Thus, the two substrates of this enzyme are UDP-D-xylose and dolichyl phosphate, whereas its two products are UDP and dolichyl D-xylosyl phosphate.
This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is UDP-D-xylose:dolichyl-phosphate D-xylosyltransferase.
References
EC 2.4.2
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Dolichyl-phosphate-mannose-protein%20mannosyltransferase | In enzymology, a dolichyl-phosphate-mannose-protein mannosyltransferase () is an enzyme that catalyzes the chemical reaction
dolichyl phosphate D-mannose + protein dolichyl phosphate + O-D-mannosylprotein
Thus, the two substrates of this enzyme are dolichyl phosphate D-mannose and protein, whereas its two products are dolichyl phosphate and O-D-mannosylprotein.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is dolichyl-phosphate-D-mannose:protein O-D-mannosyltransferase. Other names in common use include dolichol phosphomannose-protein mannosyltransferase, and protein O-D-mannosyltransferase. A human gene that codes for this enzyme is POMT1.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Dolichyl-xylosyl-phosphate%E2%80%94protein%20xylosyltransferase | In enzymology, a dolichyl-xylosyl-phosphate-protein xylosyltransferase () is an enzyme that catalyzes the chemical reaction
dolichyl D-xylosyl phosphate + protein dolichyl phosphate + D-xylosylprotein
Thus, the two substrates of this enzyme are dolichyl D-xylosyl phosphate and protein, whereas its two products are dolichyl phosphate and D-xylosylprotein.
This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is dolichyl-D-xylosyl-phosphate:protein D-xylosyltransferase.
References
EC 2.4.2
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Flavanone%207-O-beta-glucosyltransferase | In enzymology, a flavanone 7-O-beta-glucosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-glucose + a flavanone UDP + a flavanone 7-O-beta-D-glucoside
Thus, the two substrates of this enzyme are UDP-glucose and flavanone, whereas its two products are UDP and flavanone 7-O-beta-D-glucoside.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:flavanone 7-O-beta-D-glucosyltransferase. Other names in common use include uridine diphosphoglucose-flavanone 7-O-glucosyltransferase, naringenin 7-O-glucosyltransferase, and hesperetin 7-O-glucosyl-transferase.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Flavanone%207-O-glucoside%202%22-O-beta-L-rhamnosyltransferase | In enzymology, a flavanone 7-O-glucoside 2"-O-beta-L-rhamnosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-L-rhamnose + a flavanone 7-O-glucoside UDP + a flavanone 7-O-[beta-L-rhamnosyl-(1->2)-beta-D-glucoside]
Thus, the two substrates of this enzyme are UDP-L-rhamnose and flavanone 7-O-glucoside, whereas its two products are UDP and [[flavanone 7-O-[beta-L-rhamnosyl-(1->2)-beta-D-glucoside]]].
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-L-rhamnose:flavanone-7-O-glucoside 2''-O-beta-L-rhamnosyltransferase. Other names in common use include UDP-rhamnose:flavanone-7-O-glucoside-2"-O-rhamnosyltransferase, and 1->2 UDP-rhamnosyltransferase.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Flavone%207-O-beta-glucosyltransferase | In enzymology, a flavone 7-O-beta-glucosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-glucose + 5,7,3',4'-tetrahydroxyflavone UDP + 7-O-beta-D-glucosyl-5,7,3',4'-tetrahydroxyflavone
Thus, the two substrates of this enzyme are UDP-glucose and 5,7,3',4'-tetrahydroxyflavone (luteolin), whereas its two products are UDP and 7-O-beta-D-glucosyl-5,7,3',4'-tetrahydroxyflavone (cynaroside).
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:5,7,3',4'-tetrahydroxyflavone 7-O-beta-D-glucosyltransferase. Other names in common use include UDP-glucose-apigenin beta-glucosyltransferase, UDP-glucose-luteolin beta-D-glucosyltransferase, uridine diphosphoglucose-luteolin glucosyltransferase, uridine diphosphoglucose-apigenin 7-O-glucosyltransferase, and UDP-glucosyltransferase. This enzyme participates in flavonoid biosynthesis.
References
EC 2.4.1
Enzymes of unknown structure
Flavones metabolism |
https://en.wikipedia.org/wiki/Flavone%20apiosyltransferase | In enzymology, a flavone apiosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-apiose + 5,7,4'-trihydroxyflavone 7-O-beta-D-glucoside UDP + 5,7,4'-trihydroxyflavone 7-O-[beta-D-apiosyl-(1->2)-beta-D-glucoside]
Thus, the two substrates of this enzyme are UDP-apiose and 5,7,4'-trihydroxyflavone 7-O-beta-D-glucoside, whereas its 3 products are UDP, 5,7,4'-trihydroxyflavone (apigenin), and [[7-O-[beta-D-apiosyl-(1->2)-beta-D-glucoside]]].
This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is UDP-apiose:5,4'-dihydroxyflavone 7-O-beta-D-glucoside 2''-O-beta-D-apiofuranosyltransferase. Other names in common use include uridine diphosphoapiose-flavone apiosyltransferase, and UDP-apiose:7-O-(beta-D-glucosyl)-flavone apiosyltransferase. This enzyme participates in flavonoid biosynthesis.
References
EC 2.4.2
Enzymes of unknown structure
Flavones metabolism |
https://en.wikipedia.org/wiki/Flavonol-3-O-glucoside%20glucosyltransferase | In enzymology, a flavonol-3-O-glucoside glucosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-glucose + a flavonol 3-O-beta-D-glucoside UDP + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside
Thus, the two substrates of this enzyme are UDP-glucose and flavonol 3-O-beta-D-glucoside, whereas its two products are UDP and flavonol 3-O-beta-D-glucosyl-(1→2)-beta-D-glucoside.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:flavonol-3-O-glucoside 2''-O-beta-D-glucosyltransferase.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/4-alpha-glucanotransferase | In enzymology, a 4-alpha-glucanotransferase () is an enzyme that catalyzes a chemical reaction that transfers a segment of a 1,4-alpha-D-glucan to a new position in an acceptor carbohydrate, which may be glucose or a 1,4-alpha-D-glucan.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase. Other names in common use include disproportionating enzyme, dextrin glycosyltransferase, D-enzyme, debranching enzyme maltodextrin glycosyltransferase, amylomaltase, and dextrin transglycosylase. This enzyme participates in starch and sucrose metabolism in plants. Studies of the enzyme from potato led to the discovery of cycloamylose.
Structural studies
As of late 2007, 14 structures have been solved for this class of enzymes, with PDB accession codes , , , , , , , , , , , , , and .
References
EC 2.4.1
Enzymes of known structure |
https://en.wikipedia.org/wiki/Flavonol-3-O-glucoside%20L-rhamnosyltransferase | In enzymology, a flavonol-3-O-glucoside L-rhamnosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-L-rhamnose + a flavonol 3-O-D-glucoside UDP + a flavonol 3-O-[beta-L-rhamnosyl-(1->6)-beta-D-glucoside]
Thus, the two substrates of this enzyme are UDP-L-rhamnose and flavonol 3-O-D-glucoside, whereas its two products are UDP and [[flavonol 3-O-[beta-L-rhamnosyl-(1->6)-beta-D-glucoside]]].
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-L-rhamnose:flavonol-3-O-D-glucoside 6''-O-L-rhamnosyltransferase. Other names in common use include uridine diphosphorhamnose-flavonol 3-O-glucoside, rhamnosyltransferase, and UDP-rhamnose:flavonol 3-O-glucoside rhamnosyltransferase. This enzyme participates in flavonoid biosynthesis.
References
EC 2.4.1
Enzymes of unknown structure
Flavonols metabolism |
https://en.wikipedia.org/wiki/Flavonol%203-O-glucosyltransferase | In enzymology, a flavonol 3-O-glucosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-glucose + a flavonol UDP + a flavonol 3-O-beta-D-glucoside
Thus, the two substrates of this enzyme are UDP-glucose and flavonol, whereas its two products are UDP and flavonol 3-O-beta-D-glucoside. The flavonoids that can act as substrates within this reaction include quercetin, kaempferol, dihydrokaempferol, kaempferid, fisetin, and isorhamnetin. Flavonol 3-O-glucosyltransferase is a hexosyl group transfer enzyme.
This enzyme is known by the systematic name UPD-glucose:flavonol 3-O-D glucosyltransferase, and it participates in flavonoid biosynthesis and causes the formation of anthocyanins. Anthocyanins produce a purple color in the plant tissues that they are present in.
It is an enzyme found most notably in grapes (Vitis vinifera). This enzyme is found within a number of other plants as well—such as snapdragons (Antirrhinum majus), kale (Brassica oleracea), and grapefruit (Citrus x paradisi).
Pathways
This enzyme is involved in the biosynthesis of secondary metabolites. The primary function of this enzyme within its pathway is binding a glucoside onto a flavonol molecule, forming a flavonol 3-O-glucoside. It is through this mechanism that the enzyme converts anthocyanidins to anthocyanins as a part of the phenylpropanoid pathway. One specific example would be this enzymes actions on pelargonidin. Flavonol 3-O-glucosyltransferase binds the glucoside to this prote |
https://en.wikipedia.org/wiki/Flavonol-3-O-glycoside%20glucosyltransferase | In enzymology, a flavonol-3-O-glycoside glucosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-glucose + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside UDP + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside
Thus, the two substrates of this enzyme are UDP-glucose and [[flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside]], whereas its 3 products are UDP, flavonol, and [[3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside]].
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:flavonol-3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside 2-O-beta-D-glucosyltransferase.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Flavonol-3-O-glycoside%20xylosyltransferase | In enzymology, a flavonol-3-O-glycoside xylosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-D-xylose + a flavonol 3-O-glycoside UDP + a flavonol 3-[-D-xylosyl-(1->2)-beta-D-glycoside]
Thus, the two substrates of this enzyme are UDP-D-xylose and flavonol 3-O-glycoside, whereas its two products are UDP and [[flavonol 3-[-D-xylosyl-(1->2)-beta-D-glycoside]]].
This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is UDP-D-xylose:flavonol-3-O-glycoside 2''-O-beta-D-xylosyltransferase.
References
EC 2.4.2
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Flavonol%207-O-beta-glucosyltransferase | In enzymology, a flavonol 7-O-beta-glucosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-glucose + a flavonol UDP + a flavonol 7-O-beta-D-glucoside
Thus, the two substrates of this enzyme are UDP-glucose and flavonol, whereas its two products are UDP and flavonol 7-O-beta-D-glucoside.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:flavonol 7-O-beta-D-glucosyltransferase. This enzyme is also called UDP-glucose:flavonol 7-O-glucosyltransferase.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Fucosylgalactoside%203-alpha-galactosyltransferase | In enzymology, a fucosylgalactoside 3-alpha-galactosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-galactose + alpha-L-fucosyl-(1->2)-D-galactosyl-R UDP + alpha-D-galactosyl-(1->3)-[alpha-L-fucosyl(1->2)]-D-galactosyl-R
Thus, the two substrates of this enzyme are UDP-galactose and [[alpha-L-fucosyl-(1->2)-D-galactosyl-R]], whereas its two products are UDP and [[alpha-D-galactosyl-(1->3)-[alpha-L-fucosyl(1->2)]-D-galactosyl-R]].
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:alpha-L-fucosyl-(1->2)-D-galactoside 3-alpha-D-galactosyltransferase. Other names in common use include UDP-galactose:O-alpha-L-fucosyl(1->2)D-galactose, alpha-D-galactosyltransferase, UDPgalactose:glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose, 3-alpha-D-galactosyltransferase, [blood group substance] alpha-galactosyltransferase, blood-group substance B-dependent galactosyltransferase, glycoprotein-fucosylgalactoside alpha-galactosyltransferase, histo-blood group B transferase, and histo-blood substance B-dependent galactosyltransferase. This enzyme participates in 3 metabolic pathways: glycosphingolipid biosynthesis - lactoseries, glycosphingolipid biosynthesis - neo-lactoseries, and glycan structures - biosynthesis 2.
Structural studies
As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes , , , , , , and .
References
|
https://en.wikipedia.org/wiki/Galactinol%E2%80%94raffinose%20galactosyltransferase | In enzymology, a galactinol-raffinose galactosyltransferase () is an enzyme that catalyzes the chemical reaction
alpha-D-galactosyl-(1→3)-1D-myo-inositol + raffinose myo-inositol + stachyose
Thus, the two substrates of this enzyme are α-D-galactosyl-(1→3)-1D-myo-inositol and raffinose, whereas its two products are myo-inositol and stachyose.
This enzyme participates in galactose metabolism.
Nomenclature
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is alpha-D-galactosyl-(1→3)-myo-inositol:raffinose galactosyltransferase. Other names in common use include galactinol-raffinose galactosyltransferase, and stachyose synthetase.
References
Preiss, J. (Ed.), The Biochemistry of Plants, vol. 3, Academic Press, New York, 1980, p. 221-270.
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Galactinol%E2%80%94sucrose%20galactosyltransferase | In enzymology, a galactinol-sucrose galactosyltransferase () is an enzyme that catalyzes the chemical reaction
alpha-D-galactosyl-(1->3)-1D-myo-inositol + sucrose myo-inositol + raffinose
Thus, the two substrates of this enzyme are alpha-D-galactosyl-(1->3)-1D-myo-inositol and sucrose, whereas its two products are myo-inositol and raffinose.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is alpha-D-galactosyl-(1->3)-myo-inositol:sucrose 6-alpha-D-galactosyltransferase. Other names in common use include 1-alpha-D-galactosyl-myo-inositol:sucrose, and 6-alpha-D-galactosyltransferase. This enzyme participates in galactose metabolism.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Galactogen%206beta-galactosyltransferase | In enzymology, a galactogen 6beta-galactosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-galactose + galactogen UDP + 1,6-beta-D-galactosylgalactogen
Thus, the two substrates of this enzyme are UDP-galactose and galactogen, whereas its two products are UDP and 1,6-beta-D-galactosylgalactogen.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:galactogen beta-1,6-D-galactosyltransferase. Other names in common use include uridine diphosphogalactose-galactogen galactosyltransferase, 1,6-D-galactosyltransferase, and beta-(1-6)-D-galactosyltransferase.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Galactolipid%20galactosyltransferase | In enzymology, a galactolipid galactosyltransferase () is an enzyme that catalyzes the chemical reaction
2 3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-diacyl-sn- glycerol + 1,2-diacyl-sn-glycerol
Hence, this enzyme has one substrate, 3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol, but 3 products: [[3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-diacyl-sn-]], glycerol, and 1,2-diacyl-sn-glycerol.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is 3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol:mono-3-(beta-D-galactos yl)-1,2-diacyl-sn-glycerol beta-D-galactosyltransferase. Other names in common use include galactolipid-galactolipid galactosyltransferase, galactolipid:galactolipid galactosyltransferase, interlipid galactosyltransferase, GGGT, DGDG synthase (ambiguous), and digalactosyldiacylglycerol synthase (ambiguous). This enzyme participates in glycerolipid metabolism.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Alternansucrase | In enzymology, an alternansucrase () is an enzyme that catalyzes a chemical reaction that transfers an alpha-D-glucosyl residue from sucrose alternately to the 6- and 3-positions of the non-reducing terminal residue of an alpha-D-glucan, thereby creating a glucan with alternating alpha-1,6- and alpha-1,3-bonds. The name "alternan" was coined in 1982 (Cote & Robyt) for the glucan based on its alternating linkage structure.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is sucrose:1,6(1,3)-alpha-D-glucan 6(3)-alpha-D-glucosyltransferase. Other names in common use include sucrose-1,6(3)-alpha-glucan 6(3)-alpha-glucosyltransferase, sucrose:1,6-, 1,3-alpha-D-glucan 3-alpha- and, and 6-alpha-D-glucosyltransferase.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Galactoside%202-alpha-L-fucosyltransferase | In enzymology, a galactoside 2-alpha-L-fucosyltransferase () is an enzyme that catalyzes the chemical reaction
GDP-beta-L-fucose + beta-D-galactosyl-R GDP + alpha-L-fucosyl-1,2-beta-D-galactosyl-R
Thus, the two substrates of this enzyme are GDP-beta-L-fucose and beta-D-galactosyl-R, whereas its two products are GDP and alpha-L-fucosyl-1,2-beta-D-galactosyl-R.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP-beta-L-fucose:beta-D-galactosyl-R 2-alpha-L-fucosyltransferase. Other names in common use include blood group H alpha-2-fucosyltransferase, guanosine diphosphofucose-galactoside 2-L-fucosyltransferase, alpha-(1->2)-L-fucosyltransferase, alpha-2-fucosyltransferase, alpha-2-L-fucosyltransferase, blood-group substance H-dependent fucosyltransferase, guanosine diphosphofucose-glycoprotein 2-alpha-fucosyltransferase, guanosine diphosphofucose-lactose fucosyltransferase, GDP fucose-lactose fucosyltransferase, guanosine diphospho-L-fucose-lactose fucosyltransferase, guanosine diphosphofucose-beta-D-galactosyl-alpha-2-L-fucosyltransferase, , alpha-L-fucosyltransferase, guanosine diphosphofucose-glycoprotein 2-alpha-L-fucosyltransferase, H-gene-encoded beta-galactoside alpha1->2fucosyltransferase, secretor-type beta-galactoside alpha1->2fucosyltransferase, beta-galactoside alpha1->2fucosyltransferase, and GDP-L-fucose:lactose fucosyltransferase. This enzyme participates in 4 metabo |
https://en.wikipedia.org/wiki/Galactosyldiacylglycerol%20alpha-2%2C3-sialyltransferase | In enzymology, a galactosyldiacylglycerol alpha-2,3-sialyltransferase () is an enzyme that catalyzes the chemical reaction
CMP-N-acetylneuraminate + 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol CMP + 1,2-diacyl-3-[3-(alpha-D-N-acetylneuraminyl)-beta-D-galactosyl]-sn- glycerol
Thus, the two substrates of this enzyme are CMP-N-acetylneuraminate and 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol, whereas its 3 products are CMP, [[1,2-diacyl-3-[3-(alpha-D-N-acetylneuraminyl)-beta-D-galactosyl]-sn-]], and glycerol.
This enzyme belongs to the family of transferases, specifically those glycosyltransferases that do not transfer hexosyl or pentosyl groups. The systematic name of this enzyme class is CMP-N-acetylneuraminate:1,2-diacyl-3-beta-D-galactosyl-sn-glycerol N-acetylneuraminyltransferase. This enzyme participates in glycerolipid metabolism.
References
EC 2.4.99
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Galactosylgalactosylxylosylprotein%203-beta-glucuronosyltransferase | In enzymology, a galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-glucuronate + 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein UDP + 3-beta-D-glucuronosyl-3-beta-D-galactosyl-4-beta-D-galactosyl-O- beta-D-xylosylprotein
Thus, the two substrates of this enzyme are UDP-glucuronate and 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein, whereas its 3 products are UDP, 3-beta-D-glucuronosyl-3-beta-D-galactosyl-4-beta-D-galactosyl-O-, and beta-D-xylosylprotein.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucuronate:3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xyl osyl-protein D-glucuronosyltransferase. Other names in common use include glucuronosyltransferase I, and uridine diphosphate glucuronic acid:acceptor glucuronosyltransferase. This enzyme participates in chondroitin sulfate biosynthesis and glycan structures - biosynthesis 1. It employs one cofactor, manganese.
Structural studies
As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes , , , and .
References
EC 2.4.1
Manganese enzymes
Enzymes of known structure |
https://en.wikipedia.org/wiki/Galactosylxylosylprotein%203-beta-galactosyltransferase | In enzymology, a galactosylxylosylprotein 3-beta-galactosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-galactose + 4-beta-D-galactosyl-O-beta-D-xylosylprotein UDP + 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein
Thus, the two substrates of this enzyme are UDP-galactose and 4-beta-D-galactosyl-O-beta-D-xylosylprotein, whereas its two products are UDP and 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:4-beta-D-galactosyl-O-beta-D-xylosylprotein 3-beta-D-galactosyltransferase. Other names in common use include galactosyltransferase II, and uridine diphosphogalactose-galactosylxylose galactosyltransferase. This enzyme participates in chondroitin sulfate biosynthesis and glycan structures - biosynthesis 1. It employs one cofactor, manganese.
References
EC 2.4.1
Manganese enzymes
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Gallate%201-beta-glucosyltransferase | In enzymology, a gallate 1-beta-glucosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-glucose + gallate UDP + 1-galloyl-beta-D-glucose
Thus, the two substrates of this enzyme are UDP-glucose and gallate, whereas its two products are UDP and 1-galloyl-beta-D-glucose.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:gallate beta-D-glucosyltransferase. Other names in common use include UDP-glucose-vanillate 1-glucosyltransferase, UDPglucose:vanillate 1-O-glucosyltransferase, and UDPglucose:gallate glucosyltransferase.
References
EC 2.4.1
Enzymes of unknown structure
Phenolic acids metabolism |
https://en.wikipedia.org/wiki/Ganglioside%20galactosyltransferase | In enzymology, a ganglioside galactosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-galactose + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine UDP + D-galactosyl-1,3-beta-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine
The 2 substrates of this enzyme are UDP-galactose and N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine, whereas its 2 products are UDP and D-galactosyl-1,3-beta-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galac tosyl-D-glucosyl-N-acylsphingosine beta-1,3-D-galactosyltransferase. Other names in common use include UDP-galactose-ceramide galactosyltransferase, uridine diphosphogalactose-ceramide galactosyltransferase, UDP galactose-LAC Tet-ceramide alpha-galactosyltransferase, UDP-galactose-GM2 galactosyltransferase, uridine diphosphogalactose-GM2 galactosyltransferase, uridine diphosphate D-galactose:glycolipid galactosyltransferase, UDP-galactose:N-acetylgalactosaminyl-(N-acetylneuraminyl), galactosyl-glucosyl-ceramide galactosyltransferase, UDP-galactose-GM2 ganglioside galactosyltransferase, and GM1-synthase. This enzyme participates in glycosphin |
https://en.wikipedia.org/wiki/Gibberellin%20beta-D-glucosyltransferase | In enzymology, a gibberellin beta-D-glucosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-glucose + gibberellin UDP + gibberellin 2-O-beta-D-glucoside
Thus, the two substrates of this enzyme are UDP-glucose and gibberellin, whereas its two products are UDP and gibberellin 2-O-beta-D-glucoside.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:gibberellin 2-O-beta-D-glucosyltransferase. Other names in common use include uridine diphosphoglucose-gibberellate 7-glucosyltransferase, and uridine diphosphoglucose-gibberellate 3-O-glucosyltransferase.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Globoside%20alpha-N-acetylgalactosaminyltransferase | In enzymology, a globoside alpha-N-acetylgalactosaminyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-N-acetyl-D-galactosamine + N-acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D- glucosylceramide UDP + N-acetyl-D-galactosaminyl-N-acetyl-D-galactosaminyl-1,3-D- galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide
The 3 substrates of this enzyme are UDP-N-acetyl-D-galactosamine, N-acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-, and glucosylceramide, whereas its 3 products are UDP, N-acetyl-D-galactosaminyl-N-acetyl-D-galactosaminyl-1,3-D-, and galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-N-acetyl-D-galactosamine:N-acetyl-D-galactosaminyl-1,3-D-galacto syl-1,4-D-galactosyl-1,4-D-glucosylceramide alpha-N-acetyl-D-galactosaminyltransferase. Other names in common use include uridine diphosphoacetylgalactosamine-globoside, alpha-acetylgalactosaminyltransferase, Forssman synthase, and globoside acetylgalactosaminyltransferase. This enzyme participates in glycosphingolipid biosynthesis - globoseries and glycan structures - biosynthesis 2.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Globotriaosylceramide%203-beta-N-acetylgalactosaminyltransferase | In enzymology, a globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-N-acetyl-D-galactosamine + alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl- (11)-ceramide UDP + N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)- beta-D-galactosyl-(1->4)-beta-D-glucosyl-(11)-ceramide
The 3 substrates of this enzyme are UDP-N-acetyl-D-galactosamine, [[alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-]], and (11)-ceramide, whereas its 3 products are UDP, [[N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-]], and [[beta-D-galactosyl-(1->4)-beta-D-glucosyl-(11)-ceramide]].
Wrongly characterized previously as globotriosylceramide beta-1,6-N-acetylgalactosaminyl-transferase (
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-N-acetyl-D-galactosamine:alpha-D-galactosyl-(1->4)-beta-D-galact osyl-(1->4)-beta-D-glucosyl-(11)-ceramide III3-beta-N-acetyl-D-galactosaminyltransferase. This enzyme participates in glycosphingolipid biosynthesis - globoseries and glycan structures - biosynthesis 2.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Glucomannan%204-beta-mannosyltransferase | In enzymology, a glucomannan 4-beta-mannosyltransferase () is an enzyme that catalyzes the chemical reaction
GDP-mannose + (glucomannan)n GDP + (glucomannan)n+1
Thus, the two substrates of this enzyme are GDP-mannose and (glucomannan)n, whereas its two products are GDP and (glucomannan)n+1, a noncellulosic polysaccharide which is used in the formation of cell walls.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is GDPmannose:glucomannan 1,4-beta-D-mannosyltransferase. Other names in common use include GDP-man-beta-mannan manosyltransferase, and glucomannan-synthase.
References
"UniProtKB - Q9LZR3 (CSLA9_ARATH)" UniProt database
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Glucosaminylgalactosylglucosylceramide%20beta-galactosyltransferase | In enzymology, a glucosaminylgalactosylglucosylceramide beta-galactosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-galactose + N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D- glucosyl-(11)-ceramide UDP + beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D- galactosyl-(1->4)-beta-D-glucosyl-(11)-ceramide
The 3 substrates of this enzyme are UDP-galactose, [[N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-]], and glucosyl-(11)-ceramide, whereas its 3 products are UDP, [[beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-]], and [[galactosyl-(1->4)-beta-D-glucosyl-(11)-ceramide]].
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl- (1->4)-beta-D-glucosylceramide 3-beta-D-galactosyltransferase. Other names in common use include uridine, diphosphogalactose-acetyl-glucosaminylgalactosylglucosylceramide, galactosyltransferase, GalT-4, paragloboside synthase, glucosaminylgalactosylglucosylceramide 4-beta-galactosyltransferase, lactotriaosylceramide 4-beta-galactosyltransferase, UDP-galactose:N-acetyl-D-glucosaminyl-1,3-D-galactosyl-1,4-D-, glucosylceramide beta-D-galactosyltransferase, and UDP-Gal:LcOse3Cer(beta 1-4)galactosyltransferase.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Glucosylglycerol-phosphate%20synthase | In enzymology, a glucosylglycerol-phosphate synthase () is an enzyme that catalyzes the chemical reaction
ADP-glucose + sn-glycerol 3-phosphate 2-(beta-D-glucosyl)-sn-glycerol 3-phosphate + ADP
Thus, the two substrates of this enzyme are ADP-glucose and sn-glycerol 3-phosphate, whereas its two products are 2-(beta-D-glucosyl)-sn-glycerol 3-phosphate and ADP.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is ADP-glucose:sn-glycerol-3-phosphate 2-beta-D-glucosyltransferase.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Glycoprotein%202-beta-D-xylosyltransferase | In enzymology, a glycoprotein 2-beta-D-xylosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-D-xylose + N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N- acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D- mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D- glucosaminyl}asparagine UDP + N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N- acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-[beta-D- xylosyl-(1->2)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl- (1->4)-N-acetyl-beta-D-glucosaminyl}asparagine
The 5 substrates of this enzyme are UDP-D-xylose, [[N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-]], [[acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-]], [[mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-]], and [[glucosaminyl}asparagine]], whereas its 5 products are UDP, [[N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-]], [[acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]]-beta-D-, [[xylosyl-(1->2)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-]], and [[(1->4)-N-acetyl-beta-D-glucosaminyl}asparagine]].
This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is UDP-D-xylose:glycoprotein (D-xylose to the 3,6-disubstituted mannose of N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1-> |
https://en.wikipedia.org/wiki/Glycoprotein%203-alpha-L-fucosyltransferase | In enzymology, a glycoprotein 3-alpha-L-fucosyltransferase () is an enzyme that catalyzes the chemical reaction
GDP-L-fucose + N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N- acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D- mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D- glucosaminyl}asparagine GDP + N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N- acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D- mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L- fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminyl}asparagine
The 5 substrates of this enzyme are GDP-L-fucose, [[N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-]], [[acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-]], [[mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-]], and [[glucosaminyl}asparagine]], whereas its 5 products are GDP, [[N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-]], [[acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-]], [[mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L-]], and [[fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminyl}asparagine]].
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP-L-fucose:glycoprotein (L-fucose to asparagine-linked N-acetylglucosamine of N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-m |
https://en.wikipedia.org/wiki/LOOK%20algorithm | LOOK is a hard disk scheduling algorithm used to determine the order in which new disk read and write requests are processed.
Description
The LOOK algorithm, similar to the SCAN algorithm, honors requests on both sweep directions of the disk head, however, it additionally "looks" ahead to see if there are any requests pending in the direction of head movement. If no requests are pending in the direction of head movement, then the disk head traversal will be reversed to the opposite direction and requests on the other direction can be served. In LOOK scheduling, the arm goes only as far as final requests in each direction and then reverses direction without going all the way to the end. Consider an example, Given a disk with 200 cylinders (0-199), suppose we have 8 pending requests: 98, 183, 37, 122, 14, 124, 65, 67 and that the read/write head is currently at cylinder 53. In order to complete these requests, the arm will move in the increasing order first and then will move in decreasing order after reaching the end. So, the order in which it will execute is 65, 67, 98, 122, 124, 183, 37, 14.
LOOK avoids the starvation problem of shortest seek time first (SSTF). This is because LOOK is biased against the area recently traversed, and favors tracks clustered at the outermost and innermost edges of the platter. LOOK is also biased towards more recently arriving jobs (on average).
Variants
C-LOOK
One variant of LOOK is circular LOOK (C-LOOK). It is an effort to remove the bia |
https://en.wikipedia.org/wiki/Glycoprotein%206-alpha-L-fucosyltransferase | In enzymology, a glycoprotein 6-alpha-L-fucosyltransferase () is an enzyme that catalyzes the chemical reaction
GDP-L-fucose + N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N- acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D- mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D- glucosaminyl}asparagine GDP + N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N- acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D- mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L- fucosyl-(1->6)]-N-acetyl-beta-D-glucosaminyl}asparagine
The 2 substrates of this enzyme are GDP-L-fucose and N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}asparagine, and its 2 products are GDP and N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L-fucosyl-(1->6)]-N-acetyl-beta-D-glucosaminyl}asparagine.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP-L-fucose:glycoprotein (L-fucose to asparagine-linked N-acetylglucosamine of N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-a cetyl-beta-D-glucosaminyl-(1-> |
https://en.wikipedia.org/wiki/Glycoprotein-N-acetylgalactosamine%203-beta-galactosyltransferase | In enzymology, a glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-galactose + glycoprotein N-acetyl-D-galactosamine UDP + glycoprotein D-galactosyl-1,3-N-acetyl-D-galactosamine
Thus, the two substrates of this enzyme are UDP-galactose and glycoprotein N-acetyl-D-galactosamine, whereas its two products are UDP and glycoprotein D-galactosyl-1,3-N-acetyl-D-galactosamine.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:glycoprotein-N-acetyl-D-galactosamine 3-beta-D-galactosyltransferase. This enzyme is also called uridine diphosphogalactose-mucin beta-(1->3)-galactosyltransferase. This enzyme participates in o-glycan biosynthesis and glycan structures - biosynthesis 1.
See also
C1GALT1
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Glycosaminoglycan%20galactosyltransferase | In enzymology, a glycosaminoglycan galactosyltransferase () is an enzyme that catalyzes the chemical reaction
UDP-galactose + glycosaminoglycan UDP + D-galactosylglycosaminoglycan
Thus, the two substrates of this enzyme are UDP-galactose and glycosaminoglycan, whereas its two products are UDP and D-galactosylglycosaminoglycan.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:glycosaminoglycan D-galactosyltransferase. This enzyme is also called uridine diphosphogalactose-mucopolysaccharide galactosyltransferase.
References
EC 2.4.1
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Guanosine%20phosphorylase | In enzymology, a guanosine phosphorylase () is an enzyme that catalyzes the chemical reaction
guanosine + phosphate guanine + alpha-D-ribose 1-phosphate
Thus, the two substrates of this enzyme are guanosine and phosphate, whereas its two products are guanine and alpha-D-ribose 1-phosphate.
This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is guanosine:phosphate alpha-D-ribosyltransferase. This enzyme participates in purine metabolism.
References
EC 2.4.2
Enzymes of unknown structure |
https://en.wikipedia.org/wiki/Fibronectin%20type%20II%20domain | Fibronectin type II domain is a collagen-binding protein domain. Fibronectin is a multi-domain glycoprotein, found in a soluble form in plasma, and in an insoluble form in loose connective tissue and basement membranes, that binds cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in a number of important functions e.g., wound healing; cell adhesion; blood coagulation; cell differentiation and migration; maintenance of the cellular cytoskeleton; and tumour metastasis. The major part of the sequence of fibronectin consists of the repetition of three types of domains, which are called type I, II, and III.
Type II domain is approximately sixty amino acids long, contains four conserved cysteines involved in disulfide bonds and is part of the collagen-binding region of fibronectin. Type II domains occur two times in fibronectin. Type II domains have also been found in a range of proteins including blood coagulation factor XII; bovine seminal plasma proteins PDC-109 (BSP-A1/A2) and BSP-A3; cation-independent mannose-6-phosphate receptor; mannose receptor of macrophages; 180 Kd secretory phospholipase A2 receptor; DEC-205 receptor; 72 Kd and 92 Kd type IV collagenase (); and hepatocyte growth factor activator.
Fibronectin type II domain and Lipid bilayer interaction
Fibronectin type II domain is part of the extracellular portions of EphA2 receptor proteins. FN2 domain on EphA2 receptors bears positively-charged co |
https://en.wikipedia.org/wiki/Glutathione%20S-transferase%2C%20C-terminal%20domain | Glutathione S-transferase, C-terminal domain is a structural domain of glutathione S-transferase (GST).
GST conjugates reduced glutathione to a variety of targets including
S-crystallin from squid, the eukaryotic elongation factor
1-gamma, the HSP26 family of stress-related proteins and
auxin-regulated proteins in plants.
The glutathione molecule binds in a cleft between N and C-terminal domains. The catalytically important residues are proposed to reside in the N-terminal
domain. In plants, GSTs are encoded by a large gene family (48 GST genes in Arabidopsis) and can be divided into the phi, tau, theta, zeta, and lambda classes.
Biological function and classification
In eukaryotes, glutathione S-transferases (GSTs) participate in the detoxification of reactive electrophilic compounds by catalysing their conjugation to glutathione. The GST domain is also found in S-crystallins from squid, and proteins with no known GST activity, such as eukaryotic elongation factors 1-gamma and the HSP26 family of stress-related proteins, which include auxin-regulated proteins in plants and stringent starvation proteins in Escherichia coli. The major lens polypeptide of cephalopods is also a GST.
Bacterial GSTs of known function often have a specific, growth-supporting role in biodegradative metabolism: epoxide ring opening and tetrachlorohydroquinone reductive dehalogenation are two examples of the reactions catalysed by these bacterial GSTs. Some regulatory proteins, like the stringen |
https://en.wikipedia.org/wiki/Protein%20kinase%20domain | The protein kinase domain is a structurally conserved protein domain containing the catalytic function of protein kinases. Protein kinases are a group of enzymes that move a phosphate group onto proteins, in a process called phosphorylation. This functions as an on/off switch for many cellular processes, including metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. They also function in embryonic development, physiological responses, and in the nervous and immune system. Abnormal phosphorylation causes many human diseases, including cancer, and drugs that affect phosphorylation can treat those diseases.
Protein kinases possess a catalytic subunit which transfers the gamma phosphate from nucleoside triphosphates (almost always ATP) to the side chain of an amino acid in a protein, resulting in a conformational and/or dynamic changes affecting protein function. These enzymes fall into two broad classes, characterised with respect to substrate specificity: serine/threonine specific and tyrosine specific.
Function
Protein kinase function has been evolutionarily conserved from Escherichia coli to Homo sapiens. Protein kinases play a role in a multitude of cellular processes, including division, proliferation, apoptosis, and differentiation. Phosphorylation usually results in a functional change of the target protein by changing structure, dynamics, enzyme activity, cellular location, or association wit |
https://en.wikipedia.org/wiki/Western%20clawed%20frog | The western clawed frog (Xenopus tropicalis) is a species of frog in the family Pipidae, also known as tropical clawed frog. It is the only species in the genus Xenopus to have a diploid genome. Its genome has been sequenced, making it a significant model organism for genetics that complements the related species Xenopus laevis (the African clawed frog), a widely used vertebrate model for developmental biology. X. tropicalis also has a number of advantages over X. laevis in research, such as a much shorter generation time (<5 months), smaller size ( body length), and a larger number of eggs per spawn.
It is found in Benin, Burkina Faso, Cameroon, Ivory Coast, Equatorial Guinea, Gambia, Ghana, Guinea, Guinea-Bissau, Liberia, Nigeria, Senegal, Sierra Leone, Togo, and possibly Mali. Its natural habitats are subtropical or tropical moist lowland forests, moist savanna, rivers, intermittent rivers, swamps, freshwater lakes, intermittent freshwater lakes, freshwater marshes, intermittent freshwater marshes, rural gardens, heavily degraded former forests, water storage areas, ponds, aquaculture ponds, and canals and ditches.
Description
The western clawed frog is a medium-sized species with a somewhat flattened body and a snout-vent length of , females being larger than males. The eyes are bulging and situated high on the head and there is a short tentacle just below each eye. A row of unpigmented dermal tubercles runs along the flank from just behind the eye, and are thought to r |
https://en.wikipedia.org/wiki/Sean%20J.%20Morrison | Sean J. Morrison is a Canadian-American stem cell biologist and cancer researcher. Morrison is the director of Children's Medical Center Research Institute at UT Southwestern, a nonprofit research institute established in 2011 as a joint venture between Children’s Health System of Texas and UT Southwestern Medical Center. The CRI was established in 2011 by Morrison with the mission to perform transformative biomedical research at the interface of stem cell biology, cancer, and metabolism to better understand the biological basis of disease. He is a Howard Hughes Medical Institute Investigator and member of the National Academy of Medicine. From 2015 to 2016 Morrison served as the president of the International Society for Stem Cell Research.
Morrison’s research group studies the mechanisms that regulate stem cell function in adult tissues and the ways in which cancer cells hijack those mechanisms to enable tumor formation.
Education and awards
Morrison attend Dalhousie University and graduated with a BSc in biology and chemistry in 1991. He earned his Ph.D. in immunology in 1996 for working on the isolation and characterization of blood-forming (hematopoietic) stem cells in the laboratory of Dr. Irving L. Weissman at Stanford University. Morrison then worked as a postdoctoral fellow on the isolation and characterization of neural crest stem cells in Dr. David Anderson’s laboratory at the California Institute of Technology from 1996 to 1999. From 1999 to 2011, he was a pro |
https://en.wikipedia.org/wiki/Short-chain%20dehydrogenase | The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases. As the first member of this family to be characterised was Drosophila alcohol dehydrogenase, this family used to be called 'insect-type', or 'short-chain' alcohol dehydrogenases. Most members of this family are proteins of about 250 to 300 amino acid residues. Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis. Little sequence similarity has been found in the coenzyme binding domain although there is a large degree of structural similarity, and it has therefore been suggested that the structure of dehydrogenases has arisen through gene fusion of a common ancestral coenzyme nucleotide sequence with various substrate specific domains.
Subfamilies
Glucose/ribitol dehydrogenase
Insect alcohol dehydrogenase family
2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
Human proteins containing this domain
BDH1; BDH2; CBR1; CBR3; CBR4; DCXR; DECR1;
DECR2; DHRS1; DHRS10; DHRS13; DHRS2; DHRS3; DHRS4; DHRS4L2;
DHRS7; DHRS7B; DHRS8; DHRS9; DHRSX; FASN; FVT1; HADH2;
HPGD; HSD11B1; HSD11B2; HSD17B1; HSD17B10; HSD17B12; HSD17B13; HSD17B2;
HSD17B3; HSD17B4; |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.