Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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proteolysis | extracellular region | aminopeptidase activity metal ion binding metalloexopeptidase activity | Bacillus subtilis | 3D-structure Aminopeptidase Hydrolase Metal-binding Metalloprotease Protease Reference proteome Secreted Signal Zinc | MKKLLTVMTM | MKKLLTVMTMAVLTAGTLLLPAQSVTPAAHAVQISNSERELPFKAKHAYSTISQLSEAIGPRIAGTAAEKKSALLIASSMRKLKLDVKVQRFNIPDRLEGTLSSAGRDILLQAASGSAPTEEQGLTAPLYNAGLGYQKDFTADAKGKIALISRGDLTYYEKAKNAEAAGAKAVIIYNNKESLVPMTPNLSGNKVGIPVVGIKKEDGEALTQQKEATLKLKAFTNQTSQNIIGIKKPKNIKHPDIVYVTAHYDSVPFSPGANDNGSGTSVMLEMARVLKSVPSDKEIRFIAFGAEELGLLGSSHYVDHLSEKELKRSEVNF... | proteolysis extracellular region aminopeptidase activity metal ion binding metalloexopeptidase activity Bacillus subtilis 3D-structure Aminopeptidase Hydrolase Metal-binding Metalloprotease Protease Reference proteome Secreted Signal Zinc MKKLLTVMTM MKKLLTVMTMAVLTAGTLLLPAQSVTPAAHAVQISNSERELPFKAKHAYSTISQLSEAIGPRIAGTAAEK... |
autophagy of mitochondrion centrosome cycle centrosome separation DNA repair endocytic recycling heart development negative regulation of apoptotic process negative regulation of DNA damage response, signal transduction by p53 class mediator negative regulation of ERK1 and ERK2 cascade negative regulation of heterochro... | cytoplasm; HULC complex; nucleus | ATP binding p53 binding protein domain specific binding ubiquitin conjugating enzyme activity ubiquitin-protein transferase activity | Drosophila melanogaster | ATP-binding DNA damage DNA repair Nucleotide-binding Nucleus Reference proteome Transferase Ubl conjugation pathway | MSTPARRRLM | MSTPARRRLMRDFKRLQEDPPTGVSGAPTDNNIMIWNAVIFGPHDTPFEDGTFKLTIEFTEEYPNKPPTVRFVSKVFHPNVYADGGICLDILQNRWSPTYDVSAILTSIQSLLSDPNPNSPANSTAAQLYKENRREYEKRVKACVEQSFID | autophagy of mitochondrion centrosome cycle centrosome separation DNA repair endocytic recycling heart development negative regulation of apoptotic process negative regulation of DNA damage response, signal transduction by p53 class mediator negative regulation of ERK1 and ERK2 cascade negative regulation of heterochro... |
blood coagulation positive regulation of TOR signaling proteolysis | extracellular space | calcium ion binding phospholipid binding serine-type endopeptidase activity | Gallus gallus | Blood coagulation Calcium Cleavage on pair of basic residues Direct protein sequencing Disulfide bond EGF-like domain Gamma-carboxyglutamic acid Glycoprotein Hemostasis Hydrolase Hydroxylation Protease Reference proteome Repeat Secreted Serine protease Signal Zymogen | MAGRLLLLLL | MAGRLLLLLLCAALPDELRAEGGVFIKKESADKFLERTKRANSFLEEMKQGNIERECNEERCSKEEAREAFEDNEKTEEFWNIYVDGDQCSSNPCHYGGQCKDGLGSYTCSCLDGYQGKNCEFVIPKYCKINNGDCEQFCSIKKSVQKDVVCSCTSGYELAEDGKQCVSKVKYPCGKVLMKRIKRSVILPTNSNTNATSDQDVPSTNGSILEEVFTTTTESPTPPPRNGSSITDPNVDTRIVGGDECRPGECPWQAVLINEKGEEFCGGTILNEDFILTAAHCINQSKEIKVVVGEVDREKEEHSETTHTAEKIFVHSKY... | blood coagulation positive regulation of TOR signaling proteolysis extracellular space calcium ion binding phospholipid binding serine-type endopeptidase activity Gallus gallus Blood coagulation Calcium Cleavage on pair of basic residues Direct protein sequencing Disulfide bond EGF-like domain Gamma-carboxyglutamic aci... |
proteasomal protein catabolic process ubiquitin-dependent protein catabolic process | cytoplasm; proteasome core complex, alpha-subunit complex | endopeptidase activity threonine-type endopeptidase activity | Thermoplasma acidophilum | 3D-structure Cytoplasm Direct protein sequencing Proteasome Reference proteome | MQQGQMAYDR | MQQGQMAYDRAITVFSPDGRLFQVEYAREAVKKGSTALGMKFANGVLLISDKKVRSRLIEQNSIEKIQLIDDYVAAVTSGLVADARVLVDFARISAQQEKVTYGSLVNIENLVKRVADQMQQYTQYGGVRPYGVSLIFAGIDQIGPRLFDCDPAGTINEYKATAIGSGKDAVVSFLEREYKENLPEKEAVTLGIKALKSSLEEGEELKAPEIASITVGNKYRIYDQEEVKKFL | proteasomal protein catabolic process ubiquitin-dependent protein catabolic process cytoplasm; proteasome core complex, alpha-subunit complex endopeptidase activity threonine-type endopeptidase activity Thermoplasma acidophilum 3D-structure Cytoplasm Direct protein sequencing Proteasome Reference proteome MQQGQMAYDR MQ... |
actin-mediated cell contraction adenylate cyclase-modulating G protein-coupled receptor signaling pathway apical constriction involved in gastrulation convergent extension involved in gastrulation establishment or maintenance of cytoskeleton polarity involved in gastrulation G protein-coupled receptor signaling pathway... | brush border membrane; cytosol; heterotrimeric G-protein complex; plasma membrane | D5 dopamine receptor binding G protein activity G-protein beta/gamma-subunit complex binding GTP binding GTPase activity GTPase regulator activity metal ion binding | Drosophila melanogaster | Cytoplasm Developmental protein Gastrulation GTP-binding Magnesium Metal-binding Nucleotide-binding Reference proteome Transducer | MSGITLTKLT | MSGITLTKLTQERISIPNNNVITNGVENNIDSDTLSGTLTHLMEEHRTRVGAVTGPEAATTSTDGLISNGAERLRLQGSRLQTSRFACFRCCGNIITYLVRLRSTPEELEQRYKSKEIDKFLEKEKHTFRRQVKLLLLGAGESGKSTFLKQMRIIHGVNFDYELLLEYQSVIYQNVIRGMQVLLDAREKLNIAWGSDGREQDAYDAKLMECNSLDVPKFMEYAPPISRLWQDRGIRRAFERRREFQISDSVSYFLDEIQRLATPDYVPTHKDILHCRKATKGVYEFCVKVQNIPFVFVDVGGQRTQRQKWTRCFDSSVTS... | actin-mediated cell contraction adenylate cyclase-modulating G protein-coupled receptor signaling pathway apical constriction involved in gastrulation convergent extension involved in gastrulation establishment or maintenance of cytoskeleton polarity involved in gastrulation G protein-coupled receptor signaling pathway... |
cortical actin cytoskeleton organization germ cell development long-term memory oocyte microtubule cytoskeleton polarization oogenesis P granule assembly P granule organization pole cell formation pole plasm assembly pole plasm mRNA localization pole plasm protein localization posterior abdomen determination protein lo... | cell cortex; cytoplasm; endosome; germ cell nucleus; P granule; pole plasm; posterior cell cortex | mRNA binding | Drosophila melanogaster | 3D-structure Alternative initiation Developmental protein Endosome Phosphoprotein Reference proteome | MAAVTSEFPS | MAAVTSEFPSKPISYTSTNTSAKTYYLKSVKKRVTTCFQQLRDKLQSSGSFRKSSSSCLNQIFVRSDFSACGERFRKIFKSARKTELPELWKVPLVAHELTSRQSSQQLQVVARLFSSTQISTKEITYNSNSNTSENNMTIIESNYISVREEYPDIDSEVRAILLSHAQNGITISSIKSEYRKLTGNPFPLHDNVTDFLLTIPNVTAECSESGKRIFNLKASLKNGHLLDMVLNQKERTSDYSSGAPSLENIPRAPPRYWKNPFKRRALSQLNTSPRTVPKITDEKTKDIATRPVSLHQMANEAAESNWCYQDNWKHLNN... | cortical actin cytoskeleton organization germ cell development long-term memory oocyte microtubule cytoskeleton polarization oogenesis P granule assembly P granule organization pole cell formation pole plasm assembly pole plasm mRNA localization pole plasm protein localization posterior abdomen determination protein lo... |
dsRNA transport endoplasmic reticulum membrane organization Golgi organization intracellular protein transport neurotransmitter secretion protein localization to Golgi apparatus protein localization to Golgi membrane regulation of cell migration regulation of ER to Golgi vesicle-mediated transport regulation of protein... | Golgi apparatus; presynapse; trans-Golgi network | GTP binding GTPase activity protein domain specific binding | Drosophila melanogaster | GTP-binding Lipoprotein Myristate Nucleotide-binding Reference proteome | MGGVLSYFRG | MGGVLSYFRGLLGSREMRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVEQVTYKNLKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSADRDRIGISKDELLYMLREEELAGAILVVLANKQDMDGCMTVAEVHHALGLENLKNRTFQIFKTSATKGEGLDQAMDWLSNTLQSRK | dsRNA transport endoplasmic reticulum membrane organization Golgi organization intracellular protein transport neurotransmitter secretion protein localization to Golgi apparatus protein localization to Golgi membrane regulation of cell migration regulation of ER to Golgi vesicle-mediated transport regulation of protein... |
response to insecticide synaptic transmission, cholinergic | neuron projection; postsynaptic membrane; synapse | acetylcholine-gated monoatomic cation-selective channel activity transmembrane signaling receptor activity | Drosophila melanogaster | Alternative splicing Cell membrane Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Postsynaptic cell membrane Receptor Reference proteome RNA editing Signal Synapse Transmembrane Transmembrane helix Transport | MWHWSLLCVF | MWHWSLLCVFLLVPLANSTAPISFEANPDTKRLYDDLLSNYNRLIRPVVNNTETLTVWLGLKLSQLIEVNLKNQVMTTNLWVKQRWFDYKLRWDPEEYGGVEQLYVPSEHIWVPDIVLYNNWDGNYEVTLMTKATLKYTGEVFWEPPAIYKSSCEMNVEYFPYDEQICFMKFGSWTYNGAQVDLKHLDQIPGSNLVQVGIDLTEFYLSVEWDILEVPATKNEEYYPDTLEPFSDITFKLTMRRKTLFYTVNLIVPCVALTFLTVLVFYLPSDSGEKVTLCISILVSLTVFFLLLAEIIPPTSLAVPLLGKYLLFTMILVS... | response to insecticide synaptic transmission, cholinergic neuron projection; postsynaptic membrane; synapse acetylcholine-gated monoatomic cation-selective channel activity transmembrane signaling receptor activity Drosophila melanogaster Alternative splicing Cell membrane Disulfide bond Glycoprotein Ion channel Ion t... |
cell cycle cell division central nervous system development NLS-bearing protein import into nucleus regulation of mitotic cell cycle regulation of neurogenesis regulation of nucleocytoplasmic transport ventral cord development | condensed chromosome; cytoplasm; nucleus | chromatin binding guanyl-nucleotide exchange factor activity | Drosophila melanogaster | 3D-structure Cell cycle Cell division Cytoplasm Guanine-nucleotide releasing factor Mitosis Nucleus Phosphoprotein Reference proteome Repeat | MPRRKALTNN | MPRRKALTNNNNAGEAEQQPPKAKRARIAFHLELPKRRTVLGNVLVCGNGDVGQLGLGEDILERKRLSPVAGIPDAVDISAGGMHNLVLTKSGDIYSFGCNDEGALGRDTSEDGSESKPDLIDLPGKALCISAGDSHSACLLEDGRVFAWGSFRDSHGNMGLTIDGNKRTPIDLMEGTVCCSIASGADHLVILTTAGKVFTVGCAEQGQLGRLSERSISGEGRRGKRDLLRPTQLIITRAKPFEAIWATNYCTFMRESQTQVIWATGLNNFKQLAHETKGKEFALTPIKTELKDIRHIAGGQHHTVILTTDLKCSVVGRP... | cell cycle cell division central nervous system development NLS-bearing protein import into nucleus regulation of mitotic cell cycle regulation of neurogenesis regulation of nucleocytoplasmic transport ventral cord development condensed chromosome; cytoplasm; nucleus chromatin binding guanyl-nucleotide exchange factor ... |
cell aggregation cell-cell adhesion via plasma-membrane adhesion molecules chemical synaptic transmission myelination | myelin sheath; plasma membrane; synapse | structural molecule activity | Homo sapiens | 3D-structure Alternative splicing Cell membrane Charcot-Marie-Tooth disease Deafness Dejerine-Sottas syndrome Direct protein sequencing Disease variant Disulfide bond Glycoprotein Immunoglobulin domain Membrane Neurodegeneration Neuropathy Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix | MAPGAPSSSP | MAPGAPSSSPSPILAVLLFSSLVLSPAQAIVVYTDREVHGAVGSRVTLHCSFWSSEWVSDDISFTWRYQPEGGRDAISIFHYAKGQPYIDEVGTFKERIQWVGDPRWKDGSIVIHNLDYSDNGTFTCDVKNPPDIVGKTSQVTLYVFEKVPTRYGVVLGAVIGGVLGVVLLLLLLFYVVRYCWLRRQAALQRRLSAMEKGKLHKPGKDASKRGRQTPVLYAMLDHSRSTKAVSEKKAKGLGESRKDKK | cell aggregation cell-cell adhesion via plasma-membrane adhesion molecules chemical synaptic transmission myelination myelin sheath; plasma membrane; synapse structural molecule activity Homo sapiens 3D-structure Alternative splicing Cell membrane Charcot-Marie-Tooth disease Deafness Dejerine-Sottas syndrome Direct pro... |
DNA replication initiation DNA strand elongation involved in DNA replication DNA unwinding involved in DNA replication double-strand break repair via break-induced replication mitotic DNA replication initiation regulation of DNA-templated DNA replication initiation | alpha DNA polymerase:primase complex; centrosome; chromosome, telomeric region; CMG complex; MCM complex; membrane; nucleoplasm; nucleus; perinuclear region of cytoplasm | ATP binding ATP hydrolysis activity DNA binding helicase activity single-stranded DNA binding | Homo sapiens | 3D-structure Acetylation Alternative splicing ATP-binding Cell cycle Chromosome Direct protein sequencing DNA replication DNA-binding Glycoprotein Helicase Hydrolase Nucleotide-binding Nucleus Phosphoprotein Reference proteome | MAGTVVLDDV | MAGTVVLDDVELREAQRDYLDFLDDEEDQGIYQSKVRELISDNQYRLIVNVNDLRRKNEKRANRLLNNAFEELVAFQRALKDFVASIDATYAKQYEEFYVGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEENNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRCLPGKKGGYTSGTFRTVLIACNVKQMSKDAQPSFSAEDIAKIKKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILCL... | DNA replication initiation DNA strand elongation involved in DNA replication DNA unwinding involved in DNA replication double-strand break repair via break-induced replication mitotic DNA replication initiation regulation of DNA-templated DNA replication initiation alpha DNA polymerase:primase complex; centrosome; chro... |
DNA strand elongation involved in DNA replication DNA unwinding involved in DNA replication double-strand break repair via break-induced replication mitotic DNA replication initiation premeiotic DNA replication | centrosome; CMG complex; cytoplasm; MCM complex; nucleoplasm; nucleus; perinuclear region of cytoplasm | ATP binding ATP hydrolysis activity helicase activity single-stranded DNA binding | Mus musculus | Acetylation ATP-binding Cell cycle Chromosome DNA replication DNA-binding Glycoprotein Helicase Hydrolase Nucleotide-binding Nucleus Phosphoprotein Reference proteome | MAGTVVLDDV | MAGTVVLDDVELREAQRDYLDFLDDEEDQGIYQNKVRELISDNQYRLIVSVNDLRRKNEKRANRLLNNAFEELVAFQRALKDFVASIDATYAKQYEEFYIGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEENNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKVKPGDRIQVVGTYRCLPGKKGCYTSGTFRTVLIACNVKQMSKDIQPAFSADDIAKIKKFSKTRSKDVFEQLARSLAPSIHGHDYVKKAILCL... | DNA strand elongation involved in DNA replication DNA unwinding involved in DNA replication double-strand break repair via break-induced replication mitotic DNA replication initiation premeiotic DNA replication centrosome; CMG complex; cytoplasm; MCM complex; nucleoplasm; nucleus; perinuclear region of cytoplasm ATP bi... |
cellular response to leukemia inhibitory factor positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of histone acetylation regulation of transcription by RNA polymerase II | CCAAT-binding factor complex; chromatin; nucleoplasm; nucleus; protein-DNA complex; RNA polymerase II transcription regulator complex | DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor binding protein heterodimerization activity RNA polymerase II cis-regulatory region sequen... | Homo sapiens | 3D-structure Activator DNA-binding Isopeptide bond Nucleus Reference proteome Transcription Transcription regulation Ubl conjugation | MTMDGDSSTT | MTMDGDSSTTDASQLGISADYIGGSHYVIQPHDDTEDSMNDHEDTNGSKESFREQDIYLPIANVARIMKNAIPQTGKIAKDAKECVQECVSEFISFITSEASERCHQEKRKTINGEDILFAMSTLGFDSYVEPLKLYLQKFREAMKGEKGIGGAVTATDGLSEELTEEAFTNQLPAGLITTDGQQQNVMVYTTSYQQISGVQQIQFS | cellular response to leukemia inhibitory factor positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of histone acetylation regulation of transcription by RNA polymerase II CCAAT-binding factor complex; chromatin; nucleoplasm; nucleus; protein-DNA complex; RNA p... |
proteolysis | host cell cytoplasm; T=13 icosahedral viral capsid | metal ion binding serine-type peptidase activity structural molecule activity | Avian infectious bursal disease virus | Capsid protein Host cytoplasm Hydrolase Metal-binding Protease Serine protease T=13 icosahedral capsid protein Virion | MTNLQDQTQQ | MTNLQDQTQQIVPFIRSLLMPTTGPASIPDDTLEKHTLRSETSTYNLTVGDTGSGLIVFFPGFPGSIVGAHYTLQSNGNYKFDQMLLTAQNLPASYNYCRLVSRSLTVRSSTLPGGVYALNGTINAVTFQGSLSELTDVSYNGLMSATANINDKIGNVLVGEGVTVLSLPTSYDLGYVRLGDPIPAIGLDPKMVATCDSSDRPRVYTITAADDYQFSSQYQPGGVTITLFSANIDAITSLSIGGELVFQTSVQGLVLGATIYLIGFDGTAVITRAVAADNGLTAGTDNLMPFNLVIPTNEITQPITSIKLEIVTSKSGGQ... | proteolysis host cell cytoplasm; T=13 icosahedral viral capsid metal ion binding serine-type peptidase activity structural molecule activity Avian infectious bursal disease virus Capsid protein Host cytoplasm Hydrolase Metal-binding Protease Serine protease T=13 icosahedral capsid protein Virion MTNLQDQTQQ MTNLQDQTQQ... |
proteolysis | host cell cytoplasm; viral capsid | metal ion binding serine-type peptidase activity structural molecule activity | Avian infectious bursal disease virus | 3D-structure Capsid protein Host cytoplasm Hydrolase Metal-binding Protease Serine protease Virion | MPTTGPASIP | MPTTGPASIPDDTLEKHTLRSETSTYNLTVGDTGSGLIVFFPGFPGSIVGAHYTLQSNGNYKFDQMLLTAQNLPASYNYCRLVSRSLTVRSSTLPGGVYALNGTINAVTFQGSLSELTDVSYNGLMSATANINDKIGNVLVGEGVTVLSLPTSYDLGYVRLGDPIPAIGLDPKMVATCDSSDRPRVYTITAADDYQFSSQYQPGGVTITLFSANIDAITSLSVGGELVFRTSVHGLVLGATIYLIGFDGTTVITRAVAANTGLTTGTDNLMPFNLVIPTNEITQPITSIKLEIVTSKSGGQAGDQMLWSARGSLAVTIHG... | proteolysis host cell cytoplasm; viral capsid metal ion binding serine-type peptidase activity structural molecule activity Avian infectious bursal disease virus 3D-structure Capsid protein Host cytoplasm Hydrolase Metal-binding Protease Serine protease Virion MPTTGPASIP MPTTGPASIPDDTLEKHTLRSETSTYNLTVGDTGSGLIVFFPGFPG... |
cytoskeletal matrix organization at active zone maintenance of presynaptic active zone structure neurotransmitter secretion protein localization to plasma membrane protein secretion Rab protein signal transduction regulation of exocytosis regulation of neurotransmitter secretion regulation of short-term neuronal synapt... | endosome; plasma membrane; presynaptic active zone; synapse; synaptic vesicle; vesicle | GTP binding GTPase activity metal ion binding myosin V binding | Drosophila melanogaster | 3D-structure Cytoplasmic vesicle Exocytosis GTP-binding Lipoprotein Magnesium Metal-binding Methylation Nucleotide-binding Prenylation Protein transport Reference proteome Synapse Transport | MASGGDPKWQ | MASGGDPKWQKDAADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRHDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSWDNAQVILVGNKCDMEDQRVISFERGRQLADQLGVEFFETSAKENVNVKAVFERLVDIICDKMSESLDADPTLVGGGQKGQRLTDQPQGTPNANCNC | cytoskeletal matrix organization at active zone maintenance of presynaptic active zone structure neurotransmitter secretion protein localization to plasma membrane protein secretion Rab protein signal transduction regulation of exocytosis regulation of neurotransmitter secretion regulation of short-term neuronal synapt... |
axon extension axonal fasciculation axonogenesis central nervous system development genomic imprinting glial cell migration multicellular organismal-level homeostasis negative regulation of transcription by RNA polymerase II neuron development neuron differentiation neuron migration neurotrophin TRK receptor signaling ... | cell projection; centrosome; cytoplasm; cytosol; nuclear matrix; nucleoplasm; nucleus; protein-containing complex | DNA binding gamma-tubulin binding promoter-specific chromatin binding | Mus musculus | Cytoplasm DNA-binding Growth regulation Nucleus Reference proteome Transcription Transcription regulation | MSEQSKDLSD | MSEQSKDLSDPNFAAEVPDCEMQDSDAVPVGIPPPASLAANLAGPPCAPEGPMAAQQASPPPEERIEDVDPKILQQAAEEGRAHQPQSPARPIPAPPAPAQLVQKAHELMWYVLVKDQKRMVLWFPDMVKEVMGSYKKWCRSILRRTSVILARVFGLHLRLTNLHTMEFALVKALSPEELDRVALNNRMPMTGLLLMILSLIYVKGRGAREGAVWNVLRILGLRPWKKHSTFGDVRKIITEEFVQQNYLKYQRVPHIEPPEYEFFWGSRANREITKMQIMEFLARVFKKDPQAWPSRYREALEQARALREANLAAQAPRS... | axon extension axonal fasciculation axonogenesis central nervous system development genomic imprinting glial cell migration multicellular organismal-level homeostasis negative regulation of transcription by RNA polymerase II neuron development neuron differentiation neuron migration neurotrophin TRK receptor signaling ... |
brain development locomotory behavior post-embryonic development regulation of growth response to selenium ion selenium compound metabolic process sexual reproduction | extracellular region; extracellular space | selenium binding | Rattus norvegicus | Direct protein sequencing Disulfide bond Glycoprotein Phosphoprotein Reference proteome Secreted Selenium Selenocysteine Signal | MWRSLGLALA | MWRSLGLALALCLLPYGGAESQGQSPACKQAPPWNIGDQNPMLNSEGTVTVVALLQASUYLCLLQASRLEDLRIKLENQGYFNISYIVVNHQGSPSQLKHAHLKKQVSDHIAVYRQDEHQTDVWTLLNGNKDDFLIYDRCGRLVYHLGLPYSFLTFPYVEEAIKIAYCEKRCGNCSFTSLEDEAFCKNVSSATASKTTEPSEEHNHHKHHDKHGHEHLGSSKPSENQQPGALDVETSLPPSGLHHHHHHHKHKGQHRQGHLESUDMGASEGLQLSLAQRKLURRGCINQLLCKLSEESGAATSSCCCHCRHLIFEKSGSA... | brain development locomotory behavior post-embryonic development regulation of growth response to selenium ion selenium compound metabolic process sexual reproduction extracellular region; extracellular space selenium binding Rattus norvegicus Direct protein sequencing Disulfide bond Glycoprotein Phosphoprotein Referen... |
regulation of macroautophagy synaptic vesicle lumen acidification vacuolar acidification | clathrin-coated vesicle membrane; cytoplasm; intracellular organelle; melanosome; membrane; perinuclear region of cytoplasm; plasma membrane; synaptic vesicle; synaptic vesicle membrane; terminal bouton; vacuolar proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase, V0 domain | ATPase binding proton-transporting ATPase activity, rotational mechanism | Rattus norvegicus | 3D-structure Alternative splicing Cytoplasmic vesicle Hydrogen ion transport Ion transport Membrane Phosphoprotein Reference proteome Synapse Transmembrane Transmembrane helix Transport | MGELFRSEEM | MGELFRSEEMTLAQLFLQSEAAYCCVSELEELGKVQFRDLNPDVNVFQRKFVNEVRRCEEMDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKRNFLELTELKFILRKTQQFFDEMADPDLLEESSSLLEPNEMGRGAPLRLGFVAGVINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRVKKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVWFIKVRKMKAIYHTLNLCNIDVTQKCLI... | regulation of macroautophagy synaptic vesicle lumen acidification vacuolar acidification clathrin-coated vesicle membrane; cytoplasm; intracellular organelle; melanosome; membrane; perinuclear region of cytoplasm; plasma membrane; synaptic vesicle; synaptic vesicle membrane; terminal bouton; vacuolar proton-transportin... |
budding cell bud growth NLS-bearing protein import into nucleus nucleosome assembly nucleosome disassembly positive regulation of histone H3-K9 acetylation positive regulation of microtubule polymerization positive regulation of transcription elongation by RNA polymerase II protein localization to cell division site af... | cell division site; cellular bud neck septin collar; chromatin; cytoplasm; Gin4 complex; nucleus | chromatin binding cyclin binding DNA binding enzyme activator activity histone binding identical protein binding unfolded protein binding | Saccharomyces cerevisiae | 3D-structure Cytoplasm Direct protein sequencing DNA-binding Isopeptide bond Nucleus Phosphoprotein Reference proteome Ubl conjugation | MSDPIRTKPK | MSDPIRTKPKSSMQIDNAPTPHNTPASVLNPSYLKNGNPVRAQAQEQDDKIGTINEEDILANQPLLLQSIQDRLGSLVGQDSGYVGGLPKNVKEKLLSLKTLQSELFEVEKEFQVEMFELENKFLQKYKPIWEQRSRIISGQEQPKPEQIAKGQEIVESLNETELLVDEEEKAQNDSEEEQVKGIPSFWLTALENLPIVCDTITDRDAEVLEYLQDIGLEYLTDGRPGFKLLFRFDSSANPFFTNDILCKTYFYQKELGYSGDFIYDHAEGCEISWKDNAHNVTVDLEMRKQRNKTTKQVRTIEKITPIESFFNFFDPPK... | budding cell bud growth NLS-bearing protein import into nucleus nucleosome assembly nucleosome disassembly positive regulation of histone H3-K9 acetylation positive regulation of microtubule polymerization positive regulation of transcription elongation by RNA polymerase II protein localization to cell division site af... |
cell cycle chaperone cofactor-dependent protein refolding misfolded protein transport mitochondria-associated ubiquitin-dependent protein catabolic process nuclear protein quality control by the ubiquitin-proteasome system protein folding translational initiation tRNA import into nucleus | cytosol; cytosolic small ribosomal subunit; nucleus | DNA binding misfolded protein binding protein-folding chaperone binding unfolded protein binding | Saccharomyces cerevisiae | 3D-structure Cell cycle Chaperone Cytoplasm DNA-binding Nucleus Phosphoprotein Reference proteome | MVKETKLYDL | MVKETKLYDLLGVSPSANEQELKKGYRKAALKYHPDKPTGDTEKFKEISEAFEILNDPQKREIYDQYGLEAARSGGPSFGPGGPGGAGGAGGFPGGAGGFSGGHAFSNEDAFNIFSQFFGGSSPFGGADDSGFSFSSYPSGGGAGMGGMPGGMGGMHGGMGGMPGGFRSASSSPTYPEEETVQVNLPVSLEDLFVGKKKSFKIGRKGPHGASEKTQIDIQLKPGWKAGTKITYKNQGDYNPQTGRRKTLQFVIQEKSHPNFKRDGDDLIYTLPLSFKESLLGFSKTIQTIDGRTLPLSRVQPVQPSQTSTYPGQGMPTPK... | cell cycle chaperone cofactor-dependent protein refolding misfolded protein transport mitochondria-associated ubiquitin-dependent protein catabolic process nuclear protein quality control by the ubiquitin-proteasome system protein folding translational initiation tRNA import into nucleus cytosol; cytosolic small riboso... |
cytoplasmic microtubule organization meiotic spindle organization microtubule nucleation mitotic cell cycle mitotic cytokinesis, division site positioning mitotic sister chromatid segregation mitotic spindle midzone assembly mitotic spindle organization | cytoplasm; equatorial microtubule organizing center; gamma-tubulin complex; gamma-tubulin ring complex; gamma-tubulin small complex; half bridge of mitotic spindle pole body; inner plaque of mitotic spindle pole body; interphase microtubule organizing center; mating projection tip; microtubule; mitotic spindle pole bod... | GTP binding microtubule nucleator activity structural constituent of cytoskeleton | Schizosaccharomyces pombe | Cytoplasm Cytoskeleton GTP-binding Microtubule Nucleotide-binding Reference proteome | MGREIITLQA | MGREIITLQAGQCGNQIGSQFWQQLCLEHGIGPDGTLESFATEGVDRKDVFFYQSDDTRYIPRAILIDLEPRVVNNILSDTYGSLYNPENILITKNGGGAGNNWANGYSHAERIFEDIMDMIDREADGSDSLEGFSLLHSIAGGTGSGLGSFLLERLNDRYPKKIIQTYSVFPNSQSVSDVVVQPYNSLLALKRLTLNADSVVVLDNAALAHIAADRLHTQNPTFHQQNQLVSTVMSASTTTLRYPGYMNNDLVSIIASLIPSPRCHFLLTSYTPFTNQQVEEAKAIRKTTVLDVMRRLLLPKNQMVSVNPSKKSCFISI... | cytoplasmic microtubule organization meiotic spindle organization microtubule nucleation mitotic cell cycle mitotic cytokinesis, division site positioning mitotic sister chromatid segregation mitotic spindle midzone assembly mitotic spindle organization cytoplasm; equatorial microtubule organizing center; gamma-tubulin... |
calcineurin-mediated signaling cellular response to pheromone fungal-type cell wall organization intracellular monoatomic ion homeostasis positive regulation of DNA-templated transcription regulation of cell morphogenesis | calcineurin complex | calcium ion binding calcium-dependent protein serine/threonine phosphatase regulator activity phosphatase binding | Saccharomyces cerevisiae | Calcium Lipoprotein Metal-binding Myristate Reference proteome Repeat | MGAAPSKIVD | MGAAPSKIVDGLLEDTNFDRDEIERLRKRFMKLDRDSSGSIDKNEFMSIPGVSSNPLAGRIMEVFDADNSGDVDFQEFITGLSIFSGRGSKDEKLRFAFKIYDIDKDGFISNGELFIVLKIMVGSNLDDEQLQQIVDRTIVENDSDGDGRLSFEEFKNAIETTEVAKSLTLQYDV | calcineurin-mediated signaling cellular response to pheromone fungal-type cell wall organization intracellular monoatomic ion homeostasis positive regulation of DNA-templated transcription regulation of cell morphogenesis calcineurin complex calcium ion binding calcium-dependent protein serine/threonine phosphatase reg... |
manganese ion transport phosphate ion transport plasma membrane selenite transport polyphosphate metabolic process | endoplasmic reticulum; fungal-type vacuole; plasma membrane | inorganic phosphate transmembrane transporter activity manganese ion transmembrane transporter activity selenite:proton symporter activity | Saccharomyces cerevisiae | Isopeptide bond Membrane Phosphate transport Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport Ubl conjugation | MSSVNKDTIH | MSSVNKDTIHVAERSLHKEHLTEGGNMAFHNHLNDFAHIEDPLERRRLALESIDDEGFGWQQVKTISIAGVGFLTDSYDIFAINLGITMMSYVYWHGSMPGPSQTLLKVSTSVGTVIGQFGFGTLADIVGRKRIYGMELIIMIVCTILQTTVAHSPAINFVAVLTFYRIVMGIGIGGDYPLSSIITSEFATTKWRGAIMGAVFANQAWGQISGGIIALILVAAYKGELEYANSGAECDARCQKACDQMWRILIGLGTVLGLACLYFRLTIPESPRYQLDVNAKLELAAAAQEQDGEKKIHDTSDEDMAINGLERASTAVE... | manganese ion transport phosphate ion transport plasma membrane selenite transport polyphosphate metabolic process endoplasmic reticulum; fungal-type vacuole; plasma membrane inorganic phosphate transmembrane transporter activity manganese ion transmembrane transporter activity selenite:proton symporter activity Saccha... |
mRNA polyadenylation mRNA processing response to DNA damage checkpoint signaling RNA 3'-end processing | cytosol; mitochondrion; mRNA cleavage factor complex; mRNA cleavage stimulating factor complex; nucleus | mRNA binding | Saccharomyces cerevisiae | 3D-structure Cytoplasm mRNA processing Nucleus Reference proteome Repeat | MSSSTTPDLL | MSSSTTPDLLYPSADKVAEPSDNIHGDELRLRERIKDNPTNILSYFQLIQYLETQESYAKVREVYEQFHNTFPFYSPAWTLQLKGELARDEFETVEKILAQCLSGKLENNDLSLWSTYLDYIRRKNNLITGGQEARAVIVKAFQLVMQKCAIFEPKSSSFWNEYLNFLEQWKPFNKWEEQQRIDMLREFYKKMLCVPFDNLEKMWNRYTQWEQEINSLTARKFIGELSAEYMKARSLYQEWLNVTNGLKRASPINLRTANKKNIPQPGTSDSNIQQLQIWLNWIKWERENKLMLSEDMLSQRISYVYKQGIQYMIFSAEM... | mRNA polyadenylation mRNA processing response to DNA damage checkpoint signaling RNA 3'-end processing cytosol; mitochondrion; mRNA cleavage factor complex; mRNA cleavage stimulating factor complex; nucleus mRNA binding Saccharomyces cerevisiae 3D-structure Cytoplasm mRNA processing Nucleus Reference proteome Repeat M... |
mRNA polyadenylation mRNA processing | mRNA cleavage and polyadenylation specificity factor complex; mRNA cleavage factor complex; mRNA cleavage stimulating factor complex | molecular adaptor activity mRNA binding | Saccharomyces cerevisiae | 3D-structure mRNA processing Nucleus Reference proteome RNA-binding | MNRQSGVNAG | MNRQSGVNAGVQNNPPSRVVYLGSIPYDQTEEQILDLCSNVGPVINLKMMFDPQTGRSKGYAFIEFRDLESSASAVRNLNGYQLGSRFLKCGYSSNSDISGVSQQQQQQYNNINGNNNNNGNNNNNSNGPDFQNSGNANFLSQKFPELPSGIDVNINMTTPAMMISSELAKKPKEVQLKFLQKFQEWTRAHPEDAVSLLELCPQLSFVTAELLLTNGICKVDDLIPLASRPQEEASATNNNSVNEVVDPAVLNKQKELLKQVLQLNDSQISILPDDERMAIWDLKQKALRGEFGAF | mRNA polyadenylation mRNA processing mRNA cleavage and polyadenylation specificity factor complex; mRNA cleavage factor complex; mRNA cleavage stimulating factor complex molecular adaptor activity mRNA binding Saccharomyces cerevisiae 3D-structure mRNA processing Nucleus Reference proteome RNA-binding MNRQSGVNAG MNRQS... |
axial cellular bud site selection bipolar cellular bud site selection Ras protein signal transduction | cell cortex; cellular bud neck; incipient cellular bud site; plasma membrane | guanyl-nucleotide exchange factor activity | Saccharomyces cerevisiae | Cytoplasm Guanine-nucleotide releasing factor Reference proteome | MSPKNKYVYI | MSPKNKYVYICVEYIYIYFAKIHKQSTLSSDTTKMFVLIDNVLAYLLEQDDLFVTARFAIQGQIVSRRVNKIHISNITDVLLQQFISHTLPYNDNIVPKKILDSMRTAVRQLLEATACVSRECPLVKRSQDIKRARKRLLSDWYRLGADANMDAVLLVVNSAWRFLAVWRPFVNSIQHATQELYQNIAHYLLHGNVNIQRVTALIQLVMGQDDLLFSMDDVLQEVFRIQLYLNKMLPHNSHKWQKPSPFDSANLLLNFRDWTTDNALLQELLLSYPTINKNKHKNHSVPRLIQIWVESYWQDSETTLKDILNFWYSHLAE... | axial cellular bud site selection bipolar cellular bud site selection Ras protein signal transduction cell cortex; cellular bud neck; incipient cellular bud site; plasma membrane guanyl-nucleotide exchange factor activity Saccharomyces cerevisiae Cytoplasm Guanine-nucleotide releasing factor Reference proteome MSPKNKY... |
DNA recombinase assembly DNA strand invasion double-strand break repair error-free postreplication DNA repair heteroduplex formation meiotic DNA recombinase assembly mitotic recombination positive regulation of single-strand break repair via homologous recombination telomere maintenance via recombination | Rad51C-XRCC3 complex | ATP binding ATP hydrolysis activity ATP-dependent activity, acting on DNA ATP-dependent DNA damage sensor activity DNA strand exchange activity double-stranded DNA binding single-stranded DNA binding | Saccharomyces cerevisiae | ATP-binding DNA damage DNA repair Meiosis Nucleotide-binding Nucleus Reference proteome | MPRALSIKFD | MPRALSIKFDNTYMDLYDELPESKLLYDEEFSYLLDAVRQNGVCVVDFLTLTPKELARLIQRSINEVFRFQQLLVHEYNEKYLEICEKNSISPDNGPECFTTADVAMDELLGGGIFTHGITEIFGESSTGKSQLLMQLALSVQLSEPAGGLGGKCVYITTEGDLPTQRLESMLSSRPAYEKLGITQSNIFTVSCNDLINQEHIINVQLPILLERSKGSIKLVIIDSISHHLRVELQNKSFRESQENKNYLDRMAEKLQILAHDYSLSVVVANQVGDKPLANSPVAHRTYVTDYDYQLGWLVGWKNSTILYRQMNSLLGAS... | DNA recombinase assembly DNA strand invasion double-strand break repair error-free postreplication DNA repair heteroduplex formation meiotic DNA recombinase assembly mitotic recombination positive regulation of single-strand break repair via homologous recombination telomere maintenance via recombination Rad51C-XRCC3 c... |
protein folding in endoplasmic reticulum protein refolding protein transport response to unfolded protein ubiquitin-dependent ERAD pathway | cytoplasm; endoplasmic reticulum; endoplasmic reticulum lumen | Hsp70 protein binding metal ion binding protein-folding chaperone binding unfolded protein binding | Saccharomyces cerevisiae | Chaperone Endoplasmic reticulum Metal-binding Protein transport Reference proteome Repeat Signal Transport Zinc Zinc-finger | MIPKLYIHLI | MIPKLYIHLILSLLLLPLILAQDYYAILEIDKDATEKEIKSAYRQLSKKYHPDKNAGSEEAHQKFIEVGEAYDVLSDPEKKKIYDQFGADAVKNGGGGGGPGGPGAGGFHDPFDIFERMFQGGHGGPGGGFGQRQRQRGPMIKVQEKLSLKQFYSGSSIEFTLNLNDECDACHGSGSADGKLAQCPDCQGRGVIIQVLRMGIMTQQIQQMCGRCGGTGQIIKNECKTCHGKKVTKKNKFFHVDVPPGAPRNYMDTRVGEAEKGPDFDAGDLVIEFKEKDTENMGYRRRGDNLYRTEVLSAAEALYGGWQRTIEFLDENKP... | protein folding in endoplasmic reticulum protein refolding protein transport response to unfolded protein ubiquitin-dependent ERAD pathway cytoplasm; endoplasmic reticulum; endoplasmic reticulum lumen Hsp70 protein binding metal ion binding protein-folding chaperone binding unfolded protein binding Saccharomyces cerevi... |
defense response to insect isoleucine biosynthetic process L-serine catabolic process positive regulation of defense response protein homotetramerization response to herbivore response to insect threonine catabolic process | chloroplast | identical protein binding L-serine ammonia-lyase activity L-threonine ammonia-lyase activity pyridoxal phosphate binding | Solanum lycopersicum | 3D-structure Amino-acid biosynthesis Branched-chain amino acid biosynthesis Chloroplast Direct protein sequencing Isoleucine biosynthesis Lyase Plant defense Plastid Pyridoxal phosphate Reference proteome Repeat Transit peptide | MEFLCLAPTR | MEFLCLAPTRSFSTNPKLTKSIPSDHTSTTSRIFTYQNMRGSTMRPLALPLKMSPIVSVPDITAPVENVPAILPKVVPGELIVNKPTGGDSDELFQYLVDILASPVYDVAIESPLELAEKLSDRLGVNFYIKREDKQRVFSFKLRGAYNMMSNLSREELDKGVITASAGNHAQGVALAGQRLNCVAKIVMPTTTPQIKIDAVRALGGDVVLYGKTFDEAQTHALELSEKDGLKYIPPFDDPGVIKGQGTIGTEINRQLKDIHAVFIPVGGGGLIAGVATFFKQIAPNTKIIGVEPYGAASMTLSLHEGHRVKLSNVDTFA... | defense response to insect isoleucine biosynthetic process L-serine catabolic process positive regulation of defense response protein homotetramerization response to herbivore response to insect threonine catabolic process chloroplast identical protein binding L-serine ammonia-lyase activity L-threonine ammonia-lyase a... |
cell adhesion detection of chemical stimulus involved in sensory perception of bitter taste immune response negative regulation of cell population proliferation | collagen-containing extracellular matrix; external side of plasma membrane; extracellular exosome; extracellular region; extracellular space; nucleus | protein transmembrane transporter activity RNA nuclease activity | Homo sapiens | 3D-structure Direct protein sequencing Disulfide bond Glycoprotein Pyrrolidone carboxylic acid Reference proteome Secreted Signal | MVRMVPVLLS | MVRMVPVLLSLLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYNSKDRKSQPMGLWRQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSNGSHVLQGRFGCEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKAYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWTRAGEVQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWEAS | cell adhesion detection of chemical stimulus involved in sensory perception of bitter taste immune response negative regulation of cell population proliferation collagen-containing extracellular matrix; external side of plasma membrane; extracellular exosome; extracellular region; extracellular space; nucleus protein t... |
angiogenesis camera-type eye morphogenesis cell adhesion endothelial cell proliferation extracellular matrix organization | basement membrane; collagen trimer; extracellular space | extracellular matrix structural constituent conferring tensile strength | Mus musculus | Alternative splicing Angiogenesis Basement membrane Cell adhesion Collagen Extracellular matrix Hydroxylation Reference proteome Repeat Secreted Signal | MQGALMPLPS | MQGALMPLPSLLLLLLGCGPRVSSGGGAGGAAGYAPVKYVQPMQKGPVGPPFREGKGQYLEMPLPMLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGTGKPGVHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITVPGKPGAQGAPGPPGFRGEPGPQGEPGPRGDRGLKGDNGVGQPGLPGAPGQAGAPGPPGLPGPAGLGKPGLDGIPGAPGDKGDSGPPGVPGSRGEPGAVGPKGPPGVDGVGIPGAAGVPGPQGPVGAKGEPGLRGPPGLIGPVGYGMPGKPGPK... | angiogenesis camera-type eye morphogenesis cell adhesion endothelial cell proliferation extracellular matrix organization basement membrane; collagen trimer; extracellular space extracellular matrix structural constituent conferring tensile strength Mus musculus Alternative splicing Angiogenesis Basement membrane Cell ... |
adenylate cyclase-activating G protein-coupled receptor signaling pathway cellular response to cold cellular response to glucagon stimulus cellular response to glucose stimulus cellular response to heat cellular response to parathyroid hormone stimulus mesoderm formation mRNA processing negative regulation of glycolyti... | acrosomal vesicle; axoneme; cAMP-dependent protein kinase complex; centrosome; ciliary base; cytoplasm; cytosol; dendritic spine; glutamatergic synapse; mitochondrion; neuromuscular junction; nuclear speck; nucleus; perinuclear region of cytoplasm; plasma membrane raft; sperm flagellum | AMP-activated protein kinase activity ATP binding cAMP-dependent protein kinase activity magnesium ion binding manganese ion binding protein domain specific binding protein kinase A regulatory subunit binding protein kinase binding protein serine kinase activity protein serine/threonine kinase activity protein serine/t... | Cricetulus griseus | 3D-structure ATP-binding cAMP Cell membrane Cytoplasm Kinase Lipoprotein Membrane Mitochondrion Myristate Nucleotide-binding Nucleus Phosphoprotein Serine/threonine-protein kinase Transferase | MGNAAAAKKG | MGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFK... | adenylate cyclase-activating G protein-coupled receptor signaling pathway cellular response to cold cellular response to glucagon stimulus cellular response to glucose stimulus cellular response to heat cellular response to parathyroid hormone stimulus mesoderm formation mRNA processing negative regulation of glycolyti... |
adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway cGMP-mediated signaling mitotic cytokinesis protein autophosphorylation regulation of chemotaxis | cytoplasm | ATP binding microfilament motor activity myosin light chain kinase activity protein serine/threonine kinase activity | Dictyostelium discoideum | ATP-binding Direct protein sequencing Kinase Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MTEVEKIYEF | MTEVEKIYEFKEELGRGAFSIVYLGENKQTKQRYAIKVINKSELGKDYEKNLKMEVDILKKVNHPNIIALKELFDTPEKLYLVMELVTGGELFDKIVEKGSYSEADAANLVKKIVSAVGYLHGLNIVHRDLKPENLLLKSKENHLEVAIADFGLSKIIGQTLVMQTACGTPSYVAPEVLNATGYDKEVDMWSIGVITYILLCGFPPFYGDTVPEIFEQIMEANYEFPEEYWGGISKEAKDFIGKLLVVDVSKRLNATNALNHPWLKSNNSNNTIDTVKMKEYIVERQKTQTKLVN | adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway cGMP-mediated signaling mitotic cytokinesis protein autophosphorylation regulation of chemotaxis cytoplasm ATP binding microfilament motor activity myosin light chain kinase activity protein serine/threonine kinase activity Dictyostelium dis... |
cyanate catabolic process hydrogen sulfide biosynthetic process kidney development liver development response to toxic substance spinal cord development sulfur amino acid catabolic process transsulfuration | extracellular exosome; mitochondrial matrix; mitochondrion; neuron projection; synapse | 3-mercaptopyruvate sulfurtransferase activity identical protein binding thiosulfate sulfurtransferase activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Cytoplasm Direct protein sequencing Disulfide bond Mitochondrion Phosphoprotein Redox-active center Reference proteome Repeat Synapse Synaptosome Transferase | MASPQLCRAL | MASPQLCRALVSAQWVAEALRAPRAGQPLQLLDASWYLPKLGRDARREFEERHIPGAAFFDIDQCSDRTSPYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAVSLLDGGLRHWLRQNLPLSSGKSQPAPAEFRAQLDPAFIKTYEDIKENLESRRFQVVDSRATGRFRGTEPEPRDGIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDLSKPLVATCGSGVTACHVALGAYLCGKPDVPIYDGSWVEWYMRARPEDVISEGRGKTH | cyanate catabolic process hydrogen sulfide biosynthetic process kidney development liver development response to toxic substance spinal cord development sulfur amino acid catabolic process transsulfuration extracellular exosome; mitochondrial matrix; mitochondrion; neuron projection; synapse 3-mercaptopyruvate sulfurtr... |
adaptive immune response antigen processing and presentation of exogenous peptide antigen via MHC class II basement membrane disassembly cellular response to thyroid hormone stimulus collagen catabolic process immune response positive regulation of apoptotic signaling pathway protein processing proteolysis involved in ... | extracellular space; late endosome; lysosome; phagocytic vesicle | collagen binding cysteine-type endopeptidase activator activity involved in apoptotic process cysteine-type endopeptidase activity fibronectin binding laminin binding proteoglycan binding | Bos taurus | Cytoplasmic vesicle Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Lysosome Protease Reference proteome Secreted Signal Thiol protease Zymogen | MNWLVWALLL | MNWLVWALLLCSSAMAHVHRDPTLDHHWDLWKKTYGKQYKEKNEEVARRLIWEKNLKTVTLHNLEHSMGMHSYELGMNHLGDMTSEEVISLMSSLRVPSQWPRNVTYKSDPNQKLPDSMDWREKGCVTEVKYQGACGSCWAFSAVGALEAQVKLKTGKLVSLSAQNLVDCSTAKYGNKGCNGGFMTEAFQYIIDNNGIDSEASYPYKAMDGKCQYDVKNRAATCSRYIELPFGSEEALKEAVANKGPVSVGIDASHSSFFLYKTGVYYDPSCTQNVNHGVLVVGYGNLDGKDYWLVKNSWGLHFGDQGYIRMARNSGNHC... | adaptive immune response antigen processing and presentation of exogenous peptide antigen via MHC class II basement membrane disassembly cellular response to thyroid hormone stimulus collagen catabolic process immune response positive regulation of apoptotic signaling pathway protein processing proteolysis involved in ... |
G1/S transition of mitotic cell cycle intracellular monoatomic cation homeostasis intracellular signal transduction phosphorylation positive regulation of endocytosis protein lipoylation protein localization regulation of iron-sulfur cluster assembly | cytoplasm; mitochondrion | ATP binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity | Saccharomyces cerevisiae | ATP-binding Kinase Nucleotide-binding Reference proteome Serine/threonine-protein kinase Transferase | MTGMNDNNAA | MTGMNDNNAAIPQQTPRKHALSSKVMQLFRSGSRSSRQGKASSNIQPPSNINTNVPSASKSAKFGLHTPTTATPRVVSNPSNTAGVSKPGMYMPEYYQSASPSHSSSSASLNNHIDINTSKSSSAASLTSSVSALSLSPTSAINISSKSLSPKFSHHSNSNTAITPAPTPTASNINNVNKITNTSAPICGRFLVHKDGTHEHHLKNAKRQEKLSTMIKNMVGASKLRGEAKSAVPDIIMDPKTTLKSNKNPPTLFAGFMKQVVDMDDKYPEGAPTSGALNCPERDIYRSDQKDSKNNTHNITTTKKDRQCFAEKYGRCQE... | G1/S transition of mitotic cell cycle intracellular monoatomic cation homeostasis intracellular signal transduction phosphorylation positive regulation of endocytosis protein lipoylation protein localization regulation of iron-sulfur cluster assembly cytoplasm; mitochondrion ATP binding protein kinase activity protein ... |
DNA recombination meiotic mismatch repair mismatch repair mitotic recombination removal of nonhomologous ends replication fork arrest | cytoplasm; MutSalpha complex; MutSbeta complex; nucleus | ATP binding ATP-dependent DNA damage sensor activity DNA insertion or deletion binding double-strand/single-strand DNA junction binding double-stranded DNA binding | Saccharomyces cerevisiae | ATP-binding DNA damage DNA repair DNA-binding Nucleotide-binding Nucleus Reference proteome | MAGQPTISRF | MAGQPTISRFFKKAVKSELTHKQEQEVAVGNGAGSESICLDTDEEDNLSSVASTTVTNDSFPLKGSVSSKNSKNSEKTSGTSTTFNDIDFAKKLDRIMKRRSDENVEAEDDEEEGEEDFVKKKARKSPTAKLTPLDKQVKDLKMHHRDKVLVIRVGYKYKCFAEDAVTVSRILHIKLVPGKLTIDESNPQDCNHRQFAYCSFPDVRLNVHLERLVHHNLKVAVVEQAETSAIKKHDPGASKSSVFERKISNVFTKATFGVNSTFVLRGKRILGDTNSIWALSRDVHQGKVAKYSLISVNLNNGEVVYDEFEEPNLADEKL... | DNA recombination meiotic mismatch repair mismatch repair mitotic recombination removal of nonhomologous ends replication fork arrest cytoplasm; MutSalpha complex; MutSbeta complex; nucleus ATP binding ATP-dependent DNA damage sensor activity DNA insertion or deletion binding double-strand/single-strand DNA junction bi... |
ergosterol biosynthetic process | endoplasmic reticulum; endoplasmic reticulum membrane | delta24(24-1) sterol reductase activity delta24-sterol reductase activity | Saccharomyces cerevisiae | Endoplasmic reticulum Lipid biosynthesis Lipid metabolism Membrane NADP Oxidoreductase Reference proteome Steroid biosynthesis Steroid metabolism Sterol biosynthesis Sterol metabolism Transmembrane Transmembrane helix | MAKDNSEKLQ | MAKDNSEKLQVQGEEKKSKQPVNFLPQGKWLKPNEIEYEFGGTTGVIGMLIGFPLLMYYMWICAEFYHGKVALPKAGESWMHFIKHLYQLVLENGIPEKYDWTIFLTFWVFQIIFYYTLPGIWTKGQPLSHLKGKQLPYFCNAMWTLYVTTTLVLVLHFTNLFRLYVIIDRFGRIMTCAIISGFAFSIILYLWTLFISHDYHRMTGNHLYDFFMGAPLNPRWGILDLKMFFEVRLPWFTLYFITLGACLKQWETYGYVTPQLGVVMLAHWLYANACAKGEELIVPTWDMAYEKFGFMLIFWNIAGVPYTYCHCTLYLYYH... | ergosterol biosynthetic process endoplasmic reticulum; endoplasmic reticulum membrane delta24(24-1) sterol reductase activity delta24-sterol reductase activity Saccharomyces cerevisiae Endoplasmic reticulum Lipid biosynthesis Lipid metabolism Membrane NADP Oxidoreductase Reference proteome Steroid biosynthesis Steroid... |
phospholipid translocation phosphorylation response to pheromone triggering conjugation with cellular fusion | cytoplasm; nucleus; plasma membrane | ATP binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity | Saccharomyces cerevisiae | ATP-binding Kinase Lipid transport Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase Transport | MTQQEYRSPS | MTQQEYRSPSQRLSKGRSMSLPKIFARNLRSLQNNAPPGKNINVNCLNVNSCSLSASPSSQINMACNGNKQDLPIPFPLHVECNDSWSSSKLNKFKSMFNHNRSKSSGTTDASTSEKGTHKREPRSTIHTELLQSSIIGEPNVHSTTSSTLIPNEAICSTPNEISGSSSPDAELFTFDMPTDPSSFHTPSSPSYIAKDSRNLSNGSLNDINENEELQNFHRKISENGSASPLANLSLSNSPIDSPRKNSETRKDQIPMNITPRLRRAASEPFNTAKDGLMREDYIALKQPPSLGDIVEPRRSRRLRTKSFGNKFQDITVE... | phospholipid translocation phosphorylation response to pheromone triggering conjugation with cellular fusion cytoplasm; nucleus; plasma membrane ATP binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity Saccharomyces cerevisiae ATP-binding Kinase Lipid transport Nucleo... |
cellular bud neck septin ring organization cytoskeleton-dependent cytokinesis exit from mitosis mitotic cytokinesis septin ring assembly septum digestion after cytokinesis sporulation | ascospore wall; ascospore-type prospore; cell division site; cellular bud neck; cellular bud neck septin ring; Gin4 complex; mating projection base; mating projection tip; meiotic spindle; microtubule cytoskeleton; prospore membrane; septin complex; septin filament array; septin ring; spindle microtubule | 1-phosphatidylinositol binding GTP binding GTPase activity molecular adaptor activity phosphatidylinositol-4-phosphate binding phosphatidylinositol-5-phosphate binding structural constituent of cytoskeleton | Saccharomyces cerevisiae | 3D-structure Acetylation Cell cycle Cell division GTP-binding Membrane Nucleotide-binding Phosphoprotein Reference proteome | MDPLSSVQPA | MDPLSSVQPASYVGFDTITNQIEHRLLKKGFQFNIMVVGQSGLGKSTLINTLFASHLIDSATGDDISALPVTKTTEMKISTHTLVEDRVRLNINVIDTPGFGDFIDNSKAWEPIVKYIKEQHSQYLRKELTAQRERFITDTRVHAILYFLQPNGKELSRLDVEALKRLTEIANVIPVIGKSDTLTLDERTEFRELIQNEFEKYNFKIYPYDSEELTDEELELNRSVRSIIPFAVVGSENEIEINGETFRGRKTRWSAINVEDINQCDFVYLREFLIRTHLQDLIETTSYIHYEGFRARQLIALKENANSRSSAHMSSNAI... | cellular bud neck septin ring organization cytoskeleton-dependent cytokinesis exit from mitosis mitotic cytokinesis septin ring assembly septum digestion after cytokinesis sporulation ascospore wall; ascospore-type prospore; cell division site; cellular bud neck; cellular bud neck septin ring; Gin4 complex; mating proj... |
actin cortical patch localization actin cytoskeleton organization actin filament organization conjugation with cellular fusion endocytosis lipid tube assembly plasma membrane tubulation regulation of endocytosis response to osmotic stress response to starvation | actin cortical patch; cytosol; mating projection; mating projection tip; medial cortex; membrane raft; Rvs161p-Rvs167p complex | cytoskeletal protein binding | Saccharomyces cerevisiae | Coiled coil Cytoplasm Cytoskeleton Reference proteome | MSWEGFKKAI | MSWEGFKKAINRAGHSVIIKNVDKTIDKEYDMEERRYKVLQRAGEALQKEAKGFLDSLRAVTASQTTIAEVISNLYDDSKYVAGGGYNVGNYYLQCVQDFDSETVKQLDGPLRETVLDPITKFSTYFKEIEEAIKKRDHKKQDFDAAKAKVRRLVDKPAKDASKLPRAEKELSLAKDIFENLNNQLKTELPQLVSLRVPYFDPSFEALIKIQLRFCTDGYTRLAQIQQYLDQQSRDDYANGLLDTKIEELLGQMTSLDICALGIK | actin cortical patch localization actin cytoskeleton organization actin filament organization conjugation with cellular fusion endocytosis lipid tube assembly plasma membrane tubulation regulation of endocytosis response to osmotic stress response to starvation actin cortical patch; cytosol; mating projection; mating p... |
cell cycle osmosensory signaling MAPK cascade osmosensory signaling pathway via Sho1 osmosensor pheromone-dependent signal transduction involved in conjugation with cellular fusion regulation of cell cycle signal transduction involved in filamentous growth | cytoplasm | protein kinase regulator activity SAM domain binding | Saccharomyces cerevisiae | 3D-structure Cell cycle Growth arrest Pheromone response Phosphoprotein Reference proteome | MEDGKQAINE | MEDGKQAINEGSNDASPDLDVNGTILMNNEDFSQWSVDDVITWCISTLEVEETDPLCQRLRENDIVGDLLPELCLQDCQDLCDGDLNKAIKFKILINKMRDSKLEWKDDKTQEDMITVLKNLYTTTSAKLQEFQSQYTRLRMDVLDVMKTSSSSSPINTHGVSTTVPSSNNTIIPSSDGVSLSQTDYFDTVHNRQSPSRRESPVTVFRQPSLSHSKSLHKDSKNKVPQISTNQSHPSAVSTANTPGPSPNEALKQLRASKEDSCERILKNAMKRHNLADQDWRQYVLVICYGDQERLLELNEKPVIIFKNLKQQGLHPAI... | cell cycle osmosensory signaling MAPK cascade osmosensory signaling pathway via Sho1 osmosensor pheromone-dependent signal transduction involved in conjugation with cellular fusion regulation of cell cycle signal transduction involved in filamentous growth cytoplasm protein kinase regulator activity SAM domain binding ... |
glycerol-3-phosphate transmembrane transport glycerophosphodiester transmembrane transport transmembrane transport | cell periphery; fungal-type vacuole; plasma membrane | glycerol-3-phosphate transmembrane transporter activity glycerophosphodiester transmembrane transporter activity | Saccharomyces cerevisiae | Cell membrane Glycoprotein Membrane Reference proteome Repeat Transmembrane Transmembrane helix Transport | MEDKDITSVN | MEDKDITSVNEKEVNENTNPRIIKYDAERRATRTETSKKDKWKNIVTIIASGFALISDGYVNGSMSMLNKVFVMEYGKKNYSSKVSTRVSNAALVGIIFGQFFMGIAADYYSRKSCILVATAILVIGSALCAASHGTTVPGMFWMLTVMRGLVGIGVGAEYPTSTLSANESANEYTTTKRGGILVMVTNLPLAFGGPFATIIFLIVYKICSGTKHLEAIWRTVFAIGCFWPLSVFYFRWKTATTEVYEKGRIKRNIPYFLALKFYWKRLLGTCGTWFMYDFVTFPNGIFSSTIISSVIKDQNDLVKVAEWNLLLGVLAVL... | glycerol-3-phosphate transmembrane transport glycerophosphodiester transmembrane transport transmembrane transport cell periphery; fungal-type vacuole; plasma membrane glycerol-3-phosphate transmembrane transporter activity glycerophosphodiester transmembrane transporter activity Saccharomyces cerevisiae Cell membrane... |
cellular response to phosphate starvation nucleoside triphosphate metabolic process | membrane | nucleoside triphosphate diphosphatase activity phosphodiesterase I activity ribonucleoside triphosphate phosphatase activity | Saccharomyces cerevisiae | Glycoprotein Hydrolase Membrane Multifunctional enzyme Phosphoprotein Reference proteome Signal-anchor Transmembrane Transmembrane helix | MELQNDLESL | MELQNDLESLDNELNDFSEDPFRDDFITDEDAVRSGWRSAWTRMKYWFYKNRLKWTNNPIVIGDAKDSRDGSNFRRGIPLYELDANGQPIDTELVDENELSFGTGFHSKVPFKIIFRTLFGSLVFAIFLILMINIAKPHHSTRVLSHFGSPEFDPYVKYFNGTHEFFPLTIVISLDGFHPSLISKRNTPFLHDLYELKYDGGMNITSTPFMVPSFPTETFPNHWTLVTGQYPIHHGIVSNVFWDPDLNEEFHPGVLDPRIWNNNDTEPIWQTVQSAFDGDIPFKAATHMWPGSDVNYTKYNEEKLQPEHKNPIARERTPF... | cellular response to phosphate starvation nucleoside triphosphate metabolic process membrane nucleoside triphosphate diphosphatase activity phosphodiesterase I activity ribonucleoside triphosphate phosphatase activity Saccharomyces cerevisiae Glycoprotein Hydrolase Membrane Multifunctional enzyme Phosphoprotein Refere... |
fatty acid elongation fatty acid elongation, monounsaturated fatty acid fatty acid elongation, polyunsaturated fatty acid fatty acid elongation, saturated fatty acid late endosome to vacuole transport via multivesicular body sorting pathway sphingolipid biosynthetic process very long-chain fatty acid biosynthetic proce... | endoplasmic reticulum; endoplasmic reticulum membrane | fatty acid elongase activity | Saccharomyces cerevisiae | Endoplasmic reticulum Fatty acid biosynthesis Fatty acid metabolism Glycoprotein Lipid biosynthesis Lipid metabolism Membrane Phosphoprotein Reference proteome Transferase Transmembrane Transmembrane helix | MNSLVTQYAA | MNSLVTQYAAPLFERYPQLHDYLPTLERPFFNISLWEHFDDVVTRVTNGRFVPSEFQFIAGELPLSTLPPVLYAITAYYVIIFGGRFLLSKSKPFKLNGLFQLHNLVLTSLSLTLLLLMVEQLVPIIVQHGLYFAICNIGAWTQPLVTLYYMNYIVKFIEFIDTFFLVLKHKKLTFLHTYHHGATALLCYTQLMGTTSISWVPISLNLGVHVVMYWYYFLAARGIRVWWKEWVTRFQIIQFVLDIGFIYFAVYQKAVHLYFPILPHCGDCVGSTTATFAGCAIISSYLVLFISFYINVYKRKGTKTSRVVKRAHGGVAAK... | fatty acid elongation fatty acid elongation, monounsaturated fatty acid fatty acid elongation, polyunsaturated fatty acid fatty acid elongation, saturated fatty acid late endosome to vacuole transport via multivesicular body sorting pathway sphingolipid biosynthetic process very long-chain fatty acid biosynthetic proce... |
exonucleolytic catabolism of deadenylated mRNA exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) mRNA catabolic process mRNA processing nuclear mRNA surveillance nuclear polyadenylation-dependent mRNA catabolic process nuclear polyadenylatio... | cytoplasm; cytoplasmic exosome (RNase complex); exosome (RNase complex); nuclear exosome (RNase complex); nucleolus; nucleoplasm; nucleus | RNA binding | Saccharomyces cerevisiae | 3D-structure Acetylation Cytoplasm Direct protein sequencing Exosome Nucleus Phosphoprotein Reference proteome RNA-binding rRNA processing | MAESTTLETI | MAESTTLETIEIHPITFPPEVLARISPELSLQRHLSLGIRPCLRKYEEFRDVAIENNTLSRYADAGNIDTKNNILGSNVLKSGKTIVITSITGGIIEETSAAIKDLDDFGEEELFEVTKEEDIIANYASVYPVVEVERGRVGACTDEEMTISQKLHDSILHSRILPKKALKVKAGVRSANEDGTFSVLYPDELEDDTLNETNLKMKRKWSYVLYAKIVVLSRTGPVFDLCWNSLMYALQSVKLPRAFIDERASDLRMTIRTRGRSATIRETYEIICDQTKSVPLMINAKNIAFASNYGIVELDPECQLQNSDNSEEEEVD... | exonucleolytic catabolism of deadenylated mRNA exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) mRNA catabolic process mRNA processing nuclear mRNA surveillance nuclear polyadenylation-dependent mRNA catabolic process nuclear polyadenylatio... |
cellular response to oxidative stress mitochondrion organization positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II spindle pole body organization | chromatin; cytoplasm; nucleus | DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding | Saccharomyces cerevisiae | Cytoplasm DNA-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MMNEDISIID | MMNEDISIIDGHNSFLTEKSTVLLTQAKRTLEDEKEMITPPSSTVRKTMKEVNKRPSHPLSPDHSSPIAPSKAKRQRSDTCARSNGNLTLEEILQSLERRRINGELAKKPPYSYATLICLAILQSQEGKLTLSQIYHWIHVHFPYYKQKDASWQNSIRHNLSLNDAFIKTEKSCDGKGHFWEVRPGAETKFFKGENRGYEFVKDSLQDIGKYFEIDSTLDELEQVESGEGNDDLPDEEEREEAGKFPSIEIQLNSSPILRVSQLHHIPQLKTDNSVLNPHENLESMRNMIENDVNNIDSLEPPYVMKKYHTSLGLPSLVN... | cellular response to oxidative stress mitochondrion organization positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II spindle pole body organization chromatin; cytoplasm; nucleus DNA-binding transcription factor activity DNA-binding transcription factor activity, RN... |
maturation of SSU-rRNA nucleolar large rRNA transcription by RNA polymerase I regulation of ribosomal protein gene transcription by RNA polymerase II ribosomal small subunit assembly rRNA processing | CURI complex; nucleolus; nucleoplasm; nucleus; small-subunit processome; UTP-C complex | rRNA binding | Saccharomyces cerevisiae | 3D-structure Nucleus Reference proteome Ribosome biogenesis rRNA processing | MGIEDISAMK | MGIEDISAMKNGFIVVPFKLPDHKALPKSQEASLHFMFAKRHQSSNSNESDCLFLVNLPLLSNIEHMKKFVGQLCGKYDTVSHVEELLYNDEFGLHEVDLSALTSDLMSSTDVNEKRYTPRNTALLKFVDAASINNCWNALKKYSNLHAKHPNELFEWTYTTPSFTTFVNFYKPLDIDYLKEDIHTHMAIFEQREAQAQEDVQSSIVDEDGFTLVVGKNTKSLNSIRKKILNKNPLSKHENKAKPISNIDKKAKKDFYRFQVRERKKQEINQLLSKFKEDQERIKVMKAKRKFNPYT | maturation of SSU-rRNA nucleolar large rRNA transcription by RNA polymerase I regulation of ribosomal protein gene transcription by RNA polymerase II ribosomal small subunit assembly rRNA processing CURI complex; nucleolus; nucleoplasm; nucleus; small-subunit processome; UTP-C complex rRNA binding Saccharomyces cerevis... |
cellular response to oxidative stress protein glutathionylation | cytoplasm; nucleus | glutathione disulfide oxidoreductase activity glutathione peroxidase activity glutathione transferase activity | Saccharomyces cerevisiae | 3D-structure Cytoplasm Disulfide bond Electron transport Glutathionylation Isopeptide bond Nucleus Oxidoreductase Redox-active center Reference proteome Transferase Transport Ubl conjugation | MVSQETIKHV | MVSQETIKHVKDLIAENEIFVASKTYCPYCHAALNTLFEKLKVPRSKVLVLQLNDMKEGADIQAALYEINGQRTVPNIYINGKHIGGNDDLQELRETGELEELLEPILAN | cellular response to oxidative stress protein glutathionylation cytoplasm; nucleus glutathione disulfide oxidoreductase activity glutathione peroxidase activity glutathione transferase activity Saccharomyces cerevisiae 3D-structure Cytoplasm Disulfide bond Electron transport Glutathionylation Isopeptide bond Nucleus O... |
cluster assembly intracellular iron ion homeostasis iron-sulfur cluster assembly mitochondrial tRNA thio-modification tRNA thio-modification tRNA wobble uridine modification | cytosol; iron-sulfur cluster assembly complex; L-cysteine desulfurase complex; mitochondrion; nucleus | cysteine desulfurase activity iron-sulfur cluster binding metal ion binding pyridoxal phosphate binding | Saccharomyces cerevisiae | Iron Iron-sulfur Metal-binding Mitochondrion Pyridoxal phosphate Reference proteome Transferase Transit peptide tRNA processing | MLKSTATRSI | MLKSTATRSITRLSQVYNVPAATYRACLVSRRFYSPPAAGVKLDDNFSLETHTDIQAAAKAQASARASASGTTPDAVVASGSTAMSHAYQENTGFGTRPIYLDMQATTPTDPRVLDTMLKFYTGLYGNPHSNTHSYGWETNTAVENARAHVAKMINADPKEIIFTSGATESNNMVLKGVPRFYKKTKKHIITTRTEHKCVLEAARAMMKEGFEVTFLNVDDQGLIDLKELEDAIRPDTCLVSVMAVNNEIGVIQPIKEIGAICRKNKIYFHTDAAQAYGKIHIDVNEMNIDLLSISSHKIYGPKGIGAIYVRRRPRVRLE... | cluster assembly intracellular iron ion homeostasis iron-sulfur cluster assembly mitochondrial tRNA thio-modification tRNA thio-modification tRNA wobble uridine modification cytosol; iron-sulfur cluster assembly complex; L-cysteine desulfurase complex; mitochondrion; nucleus cysteine desulfurase activity iron-sulfur c... |
peptide metabolic process proteolysis | cytoplasm; fungal-type vacuole; Golgi apparatus; mitochondrial intermembrane space; mitochondrion | metal ion binding metalloendopeptidase activity | Saccharomyces cerevisiae | Cytoplasm Hydrolase Metal-binding Metalloprotease Phosphoprotein Protease Reference proteome Zinc | MRLLLCKNWF | MRLLLCKNWFASPVISPLLYTRSLYSMANTTSFPIAPQAPPNWSFTPSDISGKTNEIINNSNNFYDSMSKVESPSVSNFVEPFMKFENELGPIINQLTFLQHVSSDKEIRDASVNSSMKLDELNIDLSLRHDIFLQFARVWQDVQSKADSVERETFKYVEKSYKDYIHSGLELDEGNRLKIKEIKKKISVNSINFSKNLGEQKEYITFTKEQLEGVPDSILTQFETIKSDKDSNETLYKVTFKYPDIFPVMKLASSAQTRKQAFLADQNKVPENEAILLDTLKLRDELASLLGYDTYANYNLYDKMAEDSTTVMNFLNDL... | peptide metabolic process proteolysis cytoplasm; fungal-type vacuole; Golgi apparatus; mitochondrial intermembrane space; mitochondrion metal ion binding metalloendopeptidase activity Saccharomyces cerevisiae Cytoplasm Hydrolase Metal-binding Metalloprotease Phosphoprotein Protease Reference proteome Zinc MRLLLCKNWF M... |
amino acid transmembrane transport amino acid transport serine import across plasma membrane transmembrane transport | endoplasmic reticulum; plasma membrane | amino acid transmembrane transporter activity L-phenylalanine transmembrane transporter activity L-proline transmembrane transporter activity | Saccharomyces cerevisiae | Amino-acid transport Cell membrane Isopeptide bond Lipoprotein Membrane Palmitate Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport Ubl conjugation | MSSSKSLYEL | MSSSKSLYELKDLKNSSTEIHATGQDNEIEYFETGSNDRPSSQPHLGYEQHNTSAVRRFFDSFKRADQGPQDEVEATQMNDLTSAISPSSRQAQELEKNESSDNIGANTGHKSDSLKKTIQPRHVLMIALGTGIGTGLLVGNGTALVHAGPAGLLIGYAIMGSILYCIIQACGEMALVYSNLTGGYNAYPSFLVDDGFGFAVAWVYCLQWLCVCPLELVTASMTIKYWTTSVNPDVFVIIFYVLVITINIFGARGYAEAEFFFNCCKILMMTGFFILGIIIDVGGAGNDGFIGGKYWHDPGAFNGKHAIDRFKGVAATLV... | amino acid transmembrane transport amino acid transport serine import across plasma membrane transmembrane transport endoplasmic reticulum; plasma membrane amino acid transmembrane transporter activity L-phenylalanine transmembrane transporter activity L-proline transmembrane transporter activity Saccharomyces cerevisi... |
retrograde transport, endosome to Golgi small GTPase mediated signal transduction | cytosol; plasma membrane | GDP binding GTP binding GTPase activity | Saccharomyces cerevisiae | Acetylation Cell membrane GTP-binding Lipoprotein Membrane Methylation Nucleotide-binding Prenylation Reference proteome | MEYATMSSSN | MEYATMSSSNSTHNFQRKIALIGARNVGKTTLTVRFVESRFVESYYPTIENEFTRIIPYKSHDCTLEILDTAGQDEVSLLNIKSLTGVRGIILCYSIINRASFDLIPILWDKLVDQLGKDNLPVILVGTKADLGRSTKGVKRCVTKAEGEKLASTIGSQDKRNQAAFIECSAELDYNVEETFMLLLKQMERVEGTLGLDAENNNKCSIM | retrograde transport, endosome to Golgi small GTPase mediated signal transduction cytosol; plasma membrane GDP binding GTP binding GTPase activity Saccharomyces cerevisiae Acetylation Cell membrane GTP-binding Lipoprotein Membrane Methylation Nucleotide-binding Prenylation Reference proteome MEYATMSSSN MEYATMSSSNSTHNF... |
ascospore wall assembly proteolysis | ascospore wall; extracellular space; nuclear envelope | serine-type endopeptidase activity serine-type peptidase activity | Saccharomyces cerevisiae | Glycoprotein Hydrolase Protease Reference proteome Serine protease Signal Sporulation | MKPQCILISL | MKPQCILISLLVNLAYAEEYLVRFKNPTAFQQFTSNSNRSWRQFIDNKIEKKFSIGSFRGVTMNLSKNLVNKLKKSPLVADIVPNFRFEAFEGDSVNSAESSYTFNATAKYSYEDVEEEQNITYQPDAPRHLARISRHYQLPFDVGDKDRYKSWFNYYYEHDYQGQDVNAYIMDTGIFADHPEFEDRVIQGIDLTKEGFGDQNGHGTHVAGLVGSKTYGAAKRVNLVEVKVLGKDGSGEASNVLSGLEFIVEHCTKVSRPQGKKCVANLSLGSFRSPIINMAVEGAIEEGIVFVAAAGNFNLDAYWASPASAENVITVGA... | ascospore wall assembly proteolysis ascospore wall; extracellular space; nuclear envelope serine-type endopeptidase activity serine-type peptidase activity Saccharomyces cerevisiae Glycoprotein Hydrolase Protease Reference proteome Serine protease Signal Sporulation MKPQCILISL MKPQCILISLLVNLAYAEEYLVRFKNPTAFQQFTSNSNRSW... |
endoplasmic reticulum to Golgi vesicle-mediated transport intracellular protein transport vesicle fusion vesicle fusion with Golgi apparatus | endoplasmic reticulum membrane; ER to Golgi transport vesicle membrane; Golgi apparatus; Golgi membrane; late endosome membrane; membrane; SNARE complex | SNAP receptor activity SNARE binding | Saccharomyces cerevisiae | 3D-structure Acetylation Endoplasmic reticulum ER-Golgi transport Golgi apparatus Membrane Protein transport Reference proteome Transmembrane Transmembrane helix Transport | MNALYNHAVK | MNALYNHAVKQKNQLQQELARFEKNSVTAPISLQGSISATLVSLEKTVKQYAEHLNRYKEDTNAEEIDPKFANRLATLTQDLHDFTAKFKDLKQSYNENNSRTQLFGSGASHVMDSDNPFSTSETIMNKRNVGGASANGKEGSSNGGGLPLYQGLQKEQSVFERGNAQLDYILEMGQQSFENIVEQNKILSKVQDRMSNGLRTLGVSEQTITSINKRVFKDKLVFWIALILLIIGIYYVLKWLR | endoplasmic reticulum to Golgi vesicle-mediated transport intracellular protein transport vesicle fusion vesicle fusion with Golgi apparatus endoplasmic reticulum membrane; ER to Golgi transport vesicle membrane; Golgi apparatus; Golgi membrane; late endosome membrane; membrane; SNARE complex SNAP receptor activity SNA... |
methylation response to antibiotic response to tellurium ion response to toxic substance | cytosol | methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity | Escherichia coli | 3D-structure Antibiotic resistance Cytoplasm Detoxification Methyltransferase Reference proteome S-adenosyl-L-methionine Tellurium resistance Transferase | MIIRDENYFT | MIIRDENYFTDKYELTRTHSEVLEAVKVVKPGKTLDLGCGNGRNSLYLAANGYDVDAWDKNAMSIANVERIKSIENLDNLHTRVVDLNNLTFDRQYDFILSTVVLMFLEAKTIPGLIANMQRCTKPGGYNLIVAAMDTADYPCTVGFPFAFKEGELRRYYEGWERVKYNEDVGELHRTDANGNRIKLRFATMLARKK | methylation response to antibiotic response to tellurium ion response to toxic substance cytosol methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity Escherichia coli 3D-structure Antibiotic resistance Cytoplasm Detoxification Methyltransferase Reference proteome S-adenosyl-L-methionine ... |
cytoplasmic translation positive regulation of canonical Wnt signaling pathway ribosomal small subunit biogenesis translation | cytoplasm; cytosol; cytosolic ribosome; cytosolic small ribosomal subunit; Golgi apparatus; intracellular membrane-bounded organelle; membrane; nucleolus; nucleoplasm; small-subunit processome | RNA binding structural constituent of ribosome | Homo sapiens | 3D-structure Acetylation Direct protein sequencing Nucleus Reference proteome Ribonucleoprotein Ribosomal protein | MAEEGIAAGG | MAEEGIAAGGVMDVNTALQEVLKTALIHDGLARGIREAAKALDKRQAHLCVLASNCDEPMYVKLVEALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFKCKK | cytoplasmic translation positive regulation of canonical Wnt signaling pathway ribosomal small subunit biogenesis translation cytoplasm; cytosol; cytosolic ribosome; cytosolic small ribosomal subunit; Golgi apparatus; intracellular membrane-bounded organelle; membrane; nucleolus; nucleoplasm; small-subunit processome R... |
biosynthetic process cellular response to insulin stimulus L-alanine catabolic process positive regulation of gluconeogenesis response to nutrient levels response to starvation | cytoplasm; extracellular space | L-alanine:2-oxoglutarate aminotransferase activity pyridoxal phosphate binding | Rattus norvegicus | Acetylation Aminotransferase Cytoplasm Direct protein sequencing Phosphoprotein Pyridoxal phosphate Reference proteome Transferase | MASRVNDQSQ | MASRVNDQSQASRNGLKGKVLTLDTMNPCVRRVEYAVRGPIVQRALELEQELRQGVKKPFTEVIRANIGDAQAMGQRPITFFRQVLALCVYPNLLSSPDFPEDAKRRAERILQACGGHSLGAYSISSGIQPIREDVAQYIERRDGGIPADPNNIFLSTGASDAIVTMLKLLVSGEGRARTGVLIPIPQYPLYSAALAELDAVQVDYYLDEERAWALDIAELRRALCQARDRCCPRVLCVINPGNPTGQVQTRECIEAVIRFAFKEGLFLMADEVYQDNVYAEGSQFHSFKKVLMEMGPPYSTQQELASFHSVSKGYMGEC... | biosynthetic process cellular response to insulin stimulus L-alanine catabolic process positive regulation of gluconeogenesis response to nutrient levels response to starvation cytoplasm; extracellular space L-alanine:2-oxoglutarate aminotransferase activity pyridoxal phosphate binding Rattus norvegicus Acetylation Ami... |
lens induction in camera-type eye negative regulation of DNA-templated transcription negative regulation of gene expression olfactory placode formation positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transcription by RNA polymerase II | endoplasmic reticulum; intracellular membrane-bounded organelle; nucleoplasm; nucleus; RNA polymerase II transcription regulator complex; transcription regulator complex | chromatin binding DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific identical protein binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding sequence-specific DNA binding signaling receptor binding trans... | Mus musculus | Activator Alternative splicing DNA-binding Homeobox Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MNNPSETNKS | MNNPSETNKSSMESEDASTGTQTNGLDFQKQPVPVGGAISTAQAQAFLGHLHQVQLAGTSLQAAAQSLNVQSKSSEESGDSQQSSQPSSQPPSVQSAIPQTQLMLAGGQITGLTLTPAQQQLLLQQAQAQAQLLAAAVQQHSASQQHSAAGATISASAATPMTQIPLSQPIQIAQDLQQLQQLQQQNLNLQQFVLVHPTTNLQPAQFIISQTPQGQQGLLQAQNLLTQLPQQSQANLLQPQPSITLTSQPTTPTRTIAAASVQTLPQSQSTPKRIDTPSLEEPSDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGN... | lens induction in camera-type eye negative regulation of DNA-templated transcription negative regulation of gene expression olfactory placode formation positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transcription by RNA polymerase II endoplasmic reticulum; int... |
ethanol oxidation formaldehyde catabolic process | cytoplasm; cytosol | alcohol dehydrogenase activity, zinc-dependent identical protein binding S-(hydroxymethyl)glutathione dehydrogenase activity S-(hydroxymethyl)glutathione dehydrogenase NAD activity S-(hydroxymethyl)glutathione dehydrogenase NADP activity zinc ion binding | Escherichia coli | Cytoplasm Direct protein sequencing Metal-binding NAD Oxidoreductase Reference proteome Zinc | MKSRAAVAFA | MKSRAAVAFAPGKPLEIVEIDVAPPKKGEVLIKVTHTGVCHTDAFTLSGDDPEGVFPVVLGHEGAGVVVEVGEGVTSVKPGDHVIPLYTAECGECEFCRSGKTNLCVAVRETQGKGLMPDGTTRFSYNGQPLYHYMGCSTFSEYTVVAEVSLAKINPEANHEHVCLLGCGVTTGIGAVHNTAKVQPGDSVAVFGLGAIGLAVVQGARQAKAGRIIAIDTNPKKFDLARRFGATDCINPNDYDKPIKDVLLDINKWGIDHTFECIGNVNVMRAALESAHRGWGQSVIIGVAVAGQEISTRPFQLVTGRVWKGSAFGGVKGR... | ethanol oxidation formaldehyde catabolic process cytoplasm; cytosol alcohol dehydrogenase activity, zinc-dependent identical protein binding S-(hydroxymethyl)glutathione dehydrogenase activity S-(hydroxymethyl)glutathione dehydrogenase NAD activity S-(hydroxymethyl)glutathione dehydrogenase NADP activity zinc ion bindi... |
chromatin looping neural tube closure nucleosome assembly positive regulation of T-helper 17 cell lineage commitment protein localization to chromatin protein phosphorylation regulation of transcription by RNA polymerase II spermatogenesis | chromatin; cytoplasm; nuclear speck; nucleoplasm; nucleus | acetylation-dependent protein binding chromatin binding lysine-acetylated histone binding protein serine/threonine kinase activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Bromodomain Chromatin regulator Host-virus interaction Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation | MLQNVTPHNK | MLQNVTPHNKLPGEGNAGLLGLGPEAAAPGKRIRKPSLLYEGFESPTMASVPALQLTPANPPPPEVSNPKKPGRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQEEQELVVTIPKNSHKKGAKLAALQGSVTSAHQVPAVSSVSHTALYTPPPEIPTTVLNIPHPSVISSPLLKSLHSAGPPLLAVTAAPPAQPLAKKKGVKRKADTTTPTPTAILAPGSPASPPGSLEPKAARLPPMRRES... | chromatin looping neural tube closure nucleosome assembly positive regulation of T-helper 17 cell lineage commitment protein localization to chromatin protein phosphorylation regulation of transcription by RNA polymerase II spermatogenesis chromatin; cytoplasm; nuclear speck; nucleoplasm; nucleus acetylation-dependent ... |
termination of RNA polymerase III transcription transcription by RNA polymerase III transcription initiation at RNA polymerase III promoter tRNA transcription by RNA polymerase III | nucleoplasm; nucleus; RNA polymerase III complex | DNA binding | Saccharomyces cerevisiae | 3D-structure DNA-directed RNA polymerase Nucleus Phosphoprotein Reference proteome Transcription | MSSNKGNGRL | MSSNKGNGRLPSLKDSSSNGGGSAKPSLKFKPKAVARKSKEEREAAASKVKLEEESKRGNDKKHFNNKNKRVTGAGGQQRRMAKYLNNTHVISSGPLAAGNFVSEKGDLRRGFIKSEGSGSSLVQKGLETIDNGAESSENEAEDDDNEGVASKSKKKFNMGKEFEARNLIEDEDDGESEKSSDVDMDDEEWRSKRIEQLFPVRPVRVRHEDVETVKREIQEALSEKPTREPTPSVKTEPVGTGLQSYLEERERQVNEKLADLGLEKEFQSVDGKEAAAELELLNADHQHILRKLKKMNNKPERFMVFQLPTRLPAFERPA... | termination of RNA polymerase III transcription transcription by RNA polymerase III transcription initiation at RNA polymerase III promoter tRNA transcription by RNA polymerase III nucleoplasm; nucleus; RNA polymerase III complex DNA binding Saccharomyces cerevisiae 3D-structure DNA-directed RNA polymerase Nucleus Pho... |
cytoplasmic translation positive regulation of translational fidelity rRNA export from nucleus rRNA processing translation | cytoplasm; cytosol; cytosolic small ribosomal subunit; nucleolus; nucleoplasm; small-subunit processome | small ribosomal subunit rRNA binding structural constituent of ribosome | Saccharomyces cerevisiae | 3D-structure Acetylation Cytoplasm Direct protein sequencing Isopeptide bond Methylation Nucleus Reference proteome Ribonucleoprotein Ribosomal protein Ribosome biogenesis rRNA processing Ubl conjugation | MSAPEAQQQK | MSAPEAQQQKRGGFGGRNRGRPNRRGPRNTEEKGWVPVTKLGRLVKAGKITTIEEIFLHSLPVKEFQIIDTLLPGLQDEVMNIKPVQKQTRAGQRTRFKAVVVVGDSNGHVGLGIKTAKEVAGAIRAGIIIAKLSVIPIRRGYWGTNLGQPHSLATKTTGKCGSVTVRLIPAPRGSGIVASPAVKKLLQLAGVEDVYTQSNGKTRTLENTLKAAFVAIGNTYGFLTPNLWAEQPLPVSPLDIYSDEASAQKKRF | cytoplasmic translation positive regulation of translational fidelity rRNA export from nucleus rRNA processing translation cytoplasm; cytosol; cytosolic small ribosomal subunit; nucleolus; nucleoplasm; small-subunit processome small ribosomal subunit rRNA binding structural constituent of ribosome Saccharomyces cerevis... |
cellular response to interleukin-4 cytoplasmic translation translation | cytoplasm; cytosol; cytosolic ribosome; cytosolic small ribosomal subunit; nucleolus; nucleoplasm; postsynapse; ribonucleoprotein complex; ribosome; synapse | enzyme binding fibroblast growth factor binding mRNA binding protein-containing complex binding structural constituent of ribosome | Mus musculus | 3D-structure Acetylation Citrullination Cytoplasm Isopeptide bond Nucleus Phosphoprotein Reference proteome Repeat Ribonucleoprotein Ribosomal protein Ubl conjugation | MADDAGAAGG | MADDAGAAGGPGGPGGPGLGGRGGFRGGFGSGLRGRGRGRGRGRGRGRGARGGKAEDKEWIPVTKLGRLVKDMKIKSLEEIYLFSLPIKESEIIDFFLGASLKDEVLKIMPVQKQTRAGQRTRFKAFVAIGDYNGHVGLGVKCSKEVATAIRGAIILAKLSIVPVRRGYWGNKIGKPHTVPCKVTGRCGSVLVRLIPAPRGTGIVSAPVPKKLLMMAGIDDCYTSARGCTATLGNFAKATFDAISKTYSYLTPDLWKETVFTKSPYQEFTDHLVKTHTRVSVQRTQAPAVATT | cellular response to interleukin-4 cytoplasmic translation translation cytoplasm; cytosol; cytosolic ribosome; cytosolic small ribosomal subunit; nucleolus; nucleoplasm; postsynapse; ribonucleoprotein complex; ribosome; synapse enzyme binding fibroblast growth factor binding mRNA binding protein-containing complex bind... |
activation-induced cell death of T cells apoptotic process cellular response to amino acid starvation cellular response to hyperoxia cellular response to mechanical stimulus extrinsic apoptotic signaling pathway extrinsic apoptotic signaling pathway in absence of ligand Fas signaling pathway immune response motor neuro... | CD95 death-inducing signaling complex; cell surface; cytosol; death-inducing signaling complex; external side of plasma membrane; extracellular exosome; membrane raft; nuclear body; plasma membrane | calmodulin binding identical protein binding kinase binding signaling receptor activity tumor necrosis factor receptor activity | Homo sapiens | 3D-structure Alternative splicing Apoptosis Calmodulin-binding Cell membrane Direct protein sequencing Disease variant Disulfide bond Glycoprotein Lipoprotein Membrane Palmitate Phosphoprotein Receptor Reference proteome Repeat Secreted Signal Transmembrane Transmembrane helix | MLGIWTLLPL | MLGIWTLLPLVLTSVARLSSKSVNAQVTDINSKGLELRKTVTTVETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTLTSNTKCKEEGSRSNLGWLCLLLLPIPLIVWVKRKEVQKTCRKHRKENQGSHESPTLNPETVAINLSDVDLSKYITTIAGVMTLSQVKGFVRKNGVNEAKIDEIKNDNVQDTAEQKVQLLRNWHQLHGKKEAYDTLIKDLKKANLCTLAEKIQTIILKDITS... | activation-induced cell death of T cells apoptotic process cellular response to amino acid starvation cellular response to hyperoxia cellular response to mechanical stimulus extrinsic apoptotic signaling pathway extrinsic apoptotic signaling pathway in absence of ligand Fas signaling pathway immune response motor neuro... |
proteasomal protein catabolic process proteasomal ubiquitin-independent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process | cytoplasm; nucleus; proteasome complex; proteasome core complex, beta-subunit complex | endopeptidase activator activity | Saccharomyces cerevisiae | 3D-structure Cytoplasm Isopeptide bond Nucleus Phosphoprotein Proteasome Reference proteome Ubl conjugation | MSDPSSINGG | MSDPSSINGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFHYGHVFLGITGLATDVTTLNEMFRYKTNLYKLKEERAIEPETFTQLVSSSLYERRFGPYFVGPVVAGINSKSGKPFIAGFDLIGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPEDLFETISQALLNAADRDALSGWGAVVYIIKKDEVVKRYLKMRQD | proteasomal protein catabolic process proteasomal ubiquitin-independent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process cytoplasm; nucleus; proteasome complex; proteasome core complex, beta-subunit complex endopeptidase activator activity Saccharomyces cerevisiae 3D-structur... |
chromosome organization involved in meiotic cell cycle DNA recombinase assembly DNA strand invasion meiotic cell cycle meiotic joint molecule formation mitotic recombination reciprocal meiotic recombination sporulation resulting in formation of a cellular spore synaptonemal complex assembly | condensed nuclear chromosome; nucleus | ATP binding ATP hydrolysis activity ATP-dependent activity, acting on DNA ATP-dependent DNA damage sensor activity ATPase inhibitor activity DNA strand exchange activity double-stranded DNA binding single-stranded DNA binding | Saccharomyces cerevisiae | 3D-structure ATP-binding Cell cycle DNA-binding Meiosis Nucleotide-binding Nucleus Reference proteome Sporulation | MSVTGTEIDS | MSVTGTEIDSDTAKNILSVDELQNYGINASDLQKLKSGGIYTVNTVLSTTRRHLCKIKGLSEVKVEKIKEAAGKIIQVGFIPATVQLDIRQRVYSLSTGSKQLDSILGGGIMTMSITEVFGEFRCGKTQMSHTLCVTTQLPREMGGGEGKVAYIDTEGTFRPERIKQIAEGYELDPESCLANVSYARALNSEHQMELVEQLGEELSSGDYRLIVVDSIMANFRVDYCGRGELSERQQKLNQHLFKLNRLAEEFNVAVFLTNQVQSDPGASALFASADGRKPIGGHVLAHASATRILLRKGRGDERVAKLQDSPDMPEKEC... | chromosome organization involved in meiotic cell cycle DNA recombinase assembly DNA strand invasion meiotic cell cycle meiotic joint molecule formation mitotic recombination reciprocal meiotic recombination sporulation resulting in formation of a cellular spore synaptonemal complex assembly condensed nuclear chromosome... |
chromosome organization involved in meiotic cell cycle DNA recombinase assembly DNA recombination DNA strand invasion double-strand break repair double-strand break repair via homologous recombination heteroduplex formation meiotic joint molecule formation mitochondrial DNA repair mitotic recombination mitotic recombin... | condensed nuclear chromosome; mitochondrial matrix; nuclear chromosome | ATP binding ATP hydrolysis activity ATP-dependent activity, acting on DNA ATP-dependent DNA damage sensor activity DNA binding DNA strand exchange activity double-stranded DNA binding identical protein binding single-stranded DNA binding | Saccharomyces cerevisiae | 3D-structure ATP-binding Chromosome DNA damage DNA recombination DNA repair Nucleotide-binding Nucleus Reference proteome | MSQVQEQHIS | MSQVQEQHISESQLQYGNGSLMSTVPADLSQSVVDGNGNGSSEDIEATNGSGDGGGLQEQAEAQGEMEDEAYDEAALGSFVPIEKLQVNGITMADVKKLRESGLHTAEAVAYAPRKDLLEIKGISEAKADKLLNEAARLVPMGFVTAADFHMRRSELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLRLLDAAAQMMSESRFSLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLADQFGVA... | chromosome organization involved in meiotic cell cycle DNA recombinase assembly DNA recombination DNA strand invasion double-strand break repair double-strand break repair via homologous recombination heteroduplex formation meiotic joint molecule formation mitochondrial DNA repair mitotic recombination mitotic recombin... |
chaperone-mediated protein folding immune complex clearance intrinsic apoptotic signaling pathway negative regulation of amyloid fibril formation negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage negative regulation of protein-containing complex assembly positive regulation of apopt... | chromaffin granule; cytosol; endoplasmic reticulum lumen; extracellular space; Golgi apparatus; mitochondrial inner membrane; mitochondrion; nucleus; perinuclear endoplasmic reticulum lumen; perinuclear region of cytoplasm; spherical high-density lipoprotein particle | misfolded protein binding protein-folding chaperone binding ubiquitin protein ligase binding unfolded protein binding | Canis lupus familiaris | Chaperone Cytoplasm Cytoplasmic vesicle Disulfide bond Endoplasmic reticulum Glycoprotein Membrane Microsome Mitochondrion Nucleus Phosphoprotein Reference proteome Secreted Signal Ubl conjugation | MMKTLLLLVG | MMKTLLLLVGLLLTWDNGRVLGDQAVSDTELQEMSTEGSKYINKEIKNALKGVKQIKTLIEQTNEERKSLLSNLEEAKKKKEDALNDTKDSETKLKASQGVCNDTMMALWEECKPCLKQTCMKFYARVCRSGSGLVGHQLEEFLNQSSPFYFWMNGDRIDSLLENDRQQTHALDVMQDSFNRASSIMDELFQDRFFTREPQDTYHYSPFSLFQRRPFFNPKFRIARNIIPFPRFQPLNFHDMFQPFFDMIHQAQQAMDVNLHRIPYHFPIEFPEEDNRTVCKEIRHNSTGCLKMKDQCEKCQEILSVDCSSNNPAQVQLR... | chaperone-mediated protein folding immune complex clearance intrinsic apoptotic signaling pathway negative regulation of amyloid fibril formation negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage negative regulation of protein-containing complex assembly positive regulation of apopt... |
de novo' protein folding chaperone-mediated protein complex assembly negative regulation of DNA-templated transcription protein refolding protein targeting to ER protein targeting to mitochondrion protein transport response to heat response to oxygen levels tRNA import into nucleus ubiquitin-dependent ERAD pathway ubiq... | cytoplasm; cytosol; nucleus; perinuclear region of cytoplasm; transcription repressor complex; TRC complex | ATP binding ATPase activator activity Hsp70 protein binding metal ion binding protein-folding chaperone binding unfolded protein binding | Saccharomyces cerevisiae | 3D-structure Chaperone Cytoplasm Isopeptide bond Lipoprotein Metal-binding Methylation Prenylation Protein transport Reference proteome Repeat Stress response Transport Ubl conjugation Zinc Zinc-finger | MVKETKFYDI | MVKETKFYDILGVPVTATDVEIKKAYRKCALKYHPDKNPSEEAAEKFKEASAAYEILSDPEKRDIYDQFGEDGLSGAGGAGGFPGGGFGFGDDIFSQFFGAGGAQRPRGPQRGKDIKHEISASLEELYKGRTAKLALNKQILCKECEGRGGKKGAVKKCTSCNGQGIKFVTRQMGPMIQRFQTECDVCHGTGDIIDPKDRCKSCNGKKVENERKILEVHVEPGMKDGQRIVFKGEADQAPDVIPGDVVFIVSERPHKSFKRDGDDLVYEAEIDLLTAIAGGEFALEHVSGDWLKVGIVPGEVIAPGMRKVIEGKGMPIPK... | de novo' protein folding chaperone-mediated protein complex assembly negative regulation of DNA-templated transcription protein refolding protein targeting to ER protein targeting to mitochondrion protein transport response to heat response to oxygen levels tRNA import into nucleus ubiquitin-dependent ERAD pathway ubiq... |
co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway cytoplasmic polyadenylation mRNA polyadenylation | nucleoplasm; nucleus | ATP binding magnesium ion binding manganese ion binding poly(A) RNA polymerase activity RNA binding | Bos taurus | 3D-structure Acetylation Alternative splicing ATP-binding Direct protein sequencing Isopeptide bond Magnesium Manganese Metal-binding mRNA processing Nucleotide-binding Nucleus Phosphoprotein Reference proteome RNA-binding Transferase Ubl conjugation | MPFPVTTQGS | MPFPVTTQGSQQTQPPQKHYGITSPISLAAPKETDCLLTQKLVETLKPFGVFEEEEELQRRILILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPRHVDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNILGFLGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKWEWPNPVLLKQPEECNLNLPVWDPRVNPSDRYHLMPIITPAY... | co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway cytoplasmic polyadenylation mRNA polyadenylation nucleoplasm; nucleus ATP binding magnesium ion binding manganese ion binding poly(A) RNA polymerase activity RNA binding Bos taurus 3D-structure Acetylation Alternative splicing ATP-binding D... |
DNA-templated transcription positive regulation of proline catabolic process to glutamate positive regulation of transcription by RNA polymerase II proline metabolic process transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery | nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding zinc ion binding | Saccharomyces cerevisiae | 3D-structure Activator DNA-binding Metal-binding Nucleus Proline metabolism Reference proteome Transcription Transcription regulation Zinc | MVTDQGSRHS | MVTDQGSRHSIQSKQPAYVNKQPQKRQQRSSVACLSCRKRHIKCPGGNPCQKCVTSNAICEYLEPSKKIVVSTKYLQQLQKDLNDKTEENNRLKALLLERPVSVRGKDNSDDDERHINNAPSSDTLEVSSAPAAPIFDLMSNSNTASDNDNDDDNSNRITNNRSYDHSLEKYYKKAISIFKQPANANGENGNGANGHEDDDEDDEEISTNFAQRSGRLIESHNGFHYFVGSSSMTLFGLEIQSLVTKYISVKNFRPLPINTKNKILNSNLNPAISSFINSNNYLFSSYNFLNPISTIVNLNSINDNLSPLMFKIILKSDT... | DNA-templated transcription positive regulation of proline catabolic process to glutamate positive regulation of transcription by RNA polymerase II proline metabolic process transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery nucleus DNA-binding transcription activator activity, RNA pol... |
endocytosis endosomal lumen acidification Golgi lumen acidification intracellular copper ion homeostasis intracellular iron ion homeostasis protein targeting to vacuole proton transmembrane transport vacuolar acidification vacuole organization | fungal-type vacuole membrane; Golgi membrane; membrane; proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase, V0 domain | proton transmembrane transporter activity proton-transporting ATPase activity, rotational mechanism | Saccharomyces cerevisiae | 3D-structure Hydrogen ion transport Ion transport Membrane Reference proteome Transmembrane Transmembrane helix Transport Vacuole | MTELCPVYAP | MTELCPVYAPFFGAIGCASAIIFTSLGAAYGTAKSGVGICATCVLRPDLLFKNIVPVIMAGIIAIYGLVVSVLVCYSLGQKQALYTGFIQLGAGLSVGLSGLAAGFAIGIVGDAGVRGSSQQPRLFVGMILILIFAEVLGLYGLIVALLLNSRATQDVVC | endocytosis endosomal lumen acidification Golgi lumen acidification intracellular copper ion homeostasis intracellular iron ion homeostasis protein targeting to vacuole proton transmembrane transport vacuolar acidification vacuole organization fungal-type vacuole membrane; Golgi membrane; membrane; proton-transporting ... |
anaerobic respiration citrate metabolic process glyoxylate cycle response to oxidative stress tricarboxylic acid cycle | cytoplasm; cytosol | 4 iron, 4 sulfur cluster binding aconitate hydratase activity iron ion binding iron-responsive element binding metal ion binding mRNA 3'-UTR binding mRNA binding | Escherichia coli | 4Fe-4S Direct protein sequencing Iron Iron-sulfur Lyase Metal-binding Reference proteome RNA-binding Tricarboxylic acid cycle | MSSTLREASK | MSSTLREASKDTLQAKDKTYHYYSLPLAAKSLGDITRLPKSLKVLLENLLRWQDGNSVTEEDIHALAGWLKNAHADREIAYRPARVLMQDFTGVPAVVDLAAMREAVKRLGGDTAKVNPLSPVDLVIDHSVTVDRFGDDEAFEENVRLEMERNHERYVFLKWGKQAFSRFSVVPPGTGICHQVNLEYLGKAVWSELQDGEWIAYPDTLVGTDSHTTMINGLGVLGWGVGGIEAEAAMLGQPVSMLIPDVVGFKLTGKLREGITATDLVLTVTQMLRKHGVVGKFVEFYGDGLDSLPLADRATIANMSPEYGATCGFFPID... | anaerobic respiration citrate metabolic process glyoxylate cycle response to oxidative stress tricarboxylic acid cycle cytoplasm; cytosol 4 iron, 4 sulfur cluster binding aconitate hydratase activity iron ion binding iron-responsive element binding metal ion binding mRNA 3'-UTR binding mRNA binding Escherichia coli 4Fe... |
rescue of stalled ribosome response to heat ribosome disassembly | cytoplasm; cytosol | ATP binding ATP hydrolysis activity GTP binding GTPase activity guanosine tetraphosphate binding metal ion binding ribosomal large subunit binding ribosome binding rRNA binding | Escherichia coli | 3D-structure ATP-binding Cytoplasm GTP-binding Magnesium Metal-binding Nucleotide-binding Reference proteome | MFDRYDAGEQ | MFDRYDAGEQAVLVHIYFTQDKDMEDLQEFESLVSSAGVEALQVITGSRKAPHPKYFVGEGKAVEIAEAVKATGASVVLFDHALSPAQERNLERLCECRVIDRTGLILDIFAQRARTHEGKLQVELAQLRHLATRLVRGWTHLERQKGGIGLRGPGETQLETDRRLLRNRIVQIQSRLERVEKQREQGRQSRIKADVPTVSLVGYTNAGKSTLFNRITEARVYAADQLFATLDPTLRRIDVADVGETVLADTVGFIRHLPHDLVAAFKATLQETRQATLLLHVIDAADVRVQENIEAVNTVLEEIDAHEIPTLLVMNKID... | rescue of stalled ribosome response to heat ribosome disassembly cytoplasm; cytosol ATP binding ATP hydrolysis activity GTP binding GTPase activity guanosine tetraphosphate binding metal ion binding ribosomal large subunit binding ribosome binding rRNA binding Escherichia coli 3D-structure ATP-binding Cytoplasm GTP-bin... |
chaperone-mediated protein folding regulation of cytoplasmic translational fidelity response to pH tRNA methylation tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation tRNA wobble uridine modification | cytoplasm; cytosol; cytosolic tRNA wobble base thiouridylase complex; plasma membrane | GDP binding GTP binding GTPase activity identical protein binding potassium ion binding protein homodimerization activity | Escherichia coli | 3D-structure Cytoplasm GTP-binding Hydrolase Magnesium Metal-binding Nucleotide-binding Potassium Reference proteome tRNA processing | MSDNDTIVAQ | MSDNDTIVAQATPPGRGGVGILRISGFKAREVAETVLGKLPKPRYADYLPFKDADGSVLDQGIALWFPGPNSFTGEDVLELQGHGGPVILDLLLKRILTIPGLRIARPGEFSERAFLNDKLDLAQAEAIADLIDASSEQAARSALNSLQGAFSARVNHLVEALTHLRIYVEAAIDFPDEEIDFLSDGKIEAQLNDVIADLDAVRAEARQGSLLREGMKVVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLREASDEVERIGIERAWQEIEQADRVLFMVDGTTTDAVDPAEIWPEF... | chaperone-mediated protein folding regulation of cytoplasmic translational fidelity response to pH tRNA methylation tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation tRNA wobble uridine modification cytoplasm; cytosol; cytosolic tRNA wobble base thiouridylase complex; plasma membrane GDP binding GTP binding ... |
cytosine catabolic process | cytosol | 5-fluorocytosine deaminase activity cytosine deaminase activity ferrous iron binding identical protein binding isoguanine deaminase activity zinc ion binding | Escherichia coli | 3D-structure Cytosine metabolism Direct protein sequencing Hydrolase Iron Metal-binding Reference proteome Zinc | MSNNALQTII | MSNNALQTIINARLPGEEGLWQIHLQDGKISAIDAQSGVMPITENSLDAEQGLVIPPFVEPHIHLDTTQTAGQPNWNQSGTLFEGIERWAERKALLTHDDVKQRAWQTLKWQIANGIQHVRTHVDVSDATLTALKAMLEVKQEVAPWIDLQIVAFPQEGILSYPNGEALLEEALRLGADVVGAIPHFEFTREYGVESLHKTFALAQKYDRLIDVHCDEIDDEQSRFVETVAALAHHEGMGARVTASHTTAMHSYNGAYTSRLFRLLKMSGINFVANPLVNIHLQGRFDTYPKRRGITRVKEMLESGINVCFGHDDVFDPW... | cytosine catabolic process cytosol 5-fluorocytosine deaminase activity cytosine deaminase activity ferrous iron binding identical protein binding isoguanine deaminase activity zinc ion binding Escherichia coli 3D-structure Cytosine metabolism Direct protein sequencing Hydrolase Iron Metal-binding Reference proteome Zin... |
gamma-aminobutyric acid catabolic process nitrogen compound metabolic process protein homotetramerization | cytosol; protein-containing complex | glutarate-semialdehyde dehydrogenase (NADP+) activity identical protein binding NADP binding succinate-semialdehyde dehydrogenase (NAD+) activity succinate-semialdehyde dehydrogenase (NADP+) activity succinate-semialdehyde dehydrogenase activity | Escherichia coli | 3D-structure NADP Oxidoreductase Reference proteome | MKLNDSNLFR | MKLNDSNLFRQQALINGEWLDANNGEAIDVTNPANGDKLGSVPKMGADETRAAIDAANRALPAWRALTAKERATILRNWFNLMMEHQDDLARLMTLEQGKPLAEAKGEISYAASFIEWFAEEGKRIYGDTIPGHQADKRLIVIKQPIGVTAAITPWNFPAAMITRKAGPALAAGCTMVLKPASQTPFSALALAELAIRAGVPAGVFNVVTGSAGAVGNELTSNPLVRKLSFTGSTEIGRQLMEQCAKDIKKVSLELGGNAPFIVFDDADLDKAVEGALASKFRNAGQTCVCANRLYVQDGVYDRFAEKLQQAVSKLHIGD... | gamma-aminobutyric acid catabolic process nitrogen compound metabolic process protein homotetramerization cytosol; protein-containing complex glutarate-semialdehyde dehydrogenase (NADP+) activity identical protein binding NADP binding succinate-semialdehyde dehydrogenase (NAD+) activity succinate-semialdehyde dehydroge... |
cellular response to nitrogen starvation DNA damage response gamma-aminobutyric acid catabolic process gamma-aminobutyric acid transport response to carbon starvation | membrane; plasma membrane | gamma-aminobutyric acid transmembrane transporter activity secondary active transmembrane transporter activity | Escherichia coli | Amino-acid transport Cell inner membrane Cell membrane Direct protein sequencing Membrane Reference proteome Transmembrane Transmembrane helix Transport | MGQSSQPHEL | MGQSSQPHELGGGLKSRHVTMLSIAGVIGASLFVGSSVAIAEAGPAVLLAYLFAGLLVVMIMRMLAEMAVATPDTGSFSTYADKAIGRWAGYTIGWLYWWFWVLVIPLEANIAAMILHSWVPGIPIWLFSLVITLALTGSNLLSVKNYGEFEFWLALCKVIAILAFIFLGAVAISGFYPYAEVSGISRLWDSGGFMPNGFGAVLSAMLITMFSFMGAEIVTIAAAESDTPEKHIVRATNSVIWRISIFYLCSIFVVVALIPWNMPGLKAVGSYRSVLELLNIPHAKLIMDCVILLSVTSCLNSALYTASRMLYSLSRRGD... | cellular response to nitrogen starvation DNA damage response gamma-aminobutyric acid catabolic process gamma-aminobutyric acid transport response to carbon starvation membrane; plasma membrane gamma-aminobutyric acid transmembrane transporter activity secondary active transmembrane transporter activity Escherichia coli... |
nucleotide metabolic process | cytoplasm | dTTP diphosphatase activity identical protein binding manganese ion binding nucleoside triphosphate diphosphatase activity protein homodimerization activity UTP diphosphatase activity | Escherichia coli | 3D-structure Cytoplasm Hydrolase Nucleotide metabolism Reference proteome | MTSLYLASGS | MTSLYLASGSPRRQELLAQLGVTFERIVTGIEEQRQPQESAQQYVVRLAREKARAGVAQTAKDLPVLGADTIVILNGEVLEKPRDAEHAAQMLRKLSGQTHQVMTAVALADSQHILDCLVVTDVTFRTLTDEDIAGYVASDEPLDKAGAYGIQGLGGCFVRKINGSYHAVVGLPLVETYELLSNFNALREKRDKHDG | nucleotide metabolic process cytoplasm dTTP diphosphatase activity identical protein binding manganese ion binding nucleoside triphosphate diphosphatase activity protein homodimerization activity UTP diphosphatase activity Escherichia coli 3D-structure Cytoplasm Hydrolase Nucleotide metabolism Reference proteome MTSLYL... |
gamma-aminobutyric acid catabolic process L-fucose catabolic process rhamnose catabolic process | cytosol; protein-containing complex | glycolaldehyde dehydrogenase activity identical protein binding lactaldehyde dehydrogenase activity succinate-semialdehyde dehydrogenase (NAD+) activity | Escherichia coli | 3D-structure Direct protein sequencing NAD Oxidoreductase Reference proteome | MSVPVQHPMY | MSVPVQHPMYIDGQFVTWRGDAWIDVVNPATEAVISRIPDGQAEDARKAIDAAERAQPEWEALPAIERASWLRKISAGIRERASEISALIVEEGGKIQQLAEVEVAFTADYIDYMAEWARRYEGEIIQSDRPGENILLFKRALGVTTGILPWNFPFFLIARKMAPALLTGNTIVIKPSEFTPNNAIAFAKIVDEIGLPRGVFNLVLGRGETVGQELAGNPKVAMVSMTGSVSAGEKIMATAAKNITKVCLELGGKAPAIVMDDADLELAVKAIVDSRVINSGQVCNCAERVYVQKGIYDQFVNRLGEAMQAVQFGNPAER... | gamma-aminobutyric acid catabolic process L-fucose catabolic process rhamnose catabolic process cytosol; protein-containing complex glycolaldehyde dehydrogenase activity identical protein binding lactaldehyde dehydrogenase activity succinate-semialdehyde dehydrogenase (NAD+) activity Escherichia coli 3D-structure Direc... |
chromatin organization positive regulation of transcription by RNA polymerase II protein localization regulation of transcription by RNA polymerase II SAGA complex localization to transcription regulatory region | ADA complex; nucleus; SAGA complex; SLIK (SAGA-like) complex | methylated histone binding | Saccharomyces cerevisiae | 3D-structure Chromatin regulator Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MDGYWDVVVS | MDGYWDVVVSSLQDIYNANEVIPFDDELQTKKLNFLNMSKDQLQLHLNTFQEHMENVNRVHRILDNVRSNLSLMLNQSREEKSEENTEDAEEGEGTRMALSQGKKAVGKVGRSYWTSEYNPNAPILVGSEVAYKPRRGSADGEWIQCEVLKVVADGTRFEVRDPEPDELGNSGKVYKCNRKELLLIPPGFPTKNYPPGTKVLARYPETTTFYPAIVIGTKRDGTCRLRFDGEEEVDKETEVTRRLVLPSPTALANLARK | chromatin organization positive regulation of transcription by RNA polymerase II protein localization regulation of transcription by RNA polymerase II SAGA complex localization to transcription regulatory region ADA complex; nucleus; SAGA complex; SLIK (SAGA-like) complex methylated histone binding Saccharomyces cerevi... |
nuclear mRNA surveillance poly(A)+ mRNA export from nucleus telomere maintenance | chromosome, telomeric region; cytoplasm; cytoplasmic stress granule; cytosol; nucleus; P-body | chromatin binding mRNA binding single-stranded telomeric DNA binding | Saccharomyces cerevisiae | 3D-structure Chromosome Cytoplasm DNA-binding Nucleus Phosphoprotein Reference proteome Repeat RNA-binding Telomere | MERELGMYGN | MERELGMYGNDRSRSRSPVRRRLSDDRDRYDDYNDSSSNNGNGSRRQRRDRGSRFNDRYDQSYGGSRYHDDRNWPPRRGGRGRGGSRSFRGGRGGGRGRTLGPIVERDLERQFDATKRNFENSIFVRNLTFDCTPEDLKELFGTVGEVVEADIITSKGHHRGMGTVEFTKNESVQDAISKFDGALFMDRKLMVRQDNPPPEAAKEFSKKATREEIDNGFEVFIINLPYSMNWQSLKDMFKECGHVLRADVELDFNGFSRGFGSVIYPTEDEMIRAIDTFNGMEVEGRVLEVREGRFNKRKNNDRYNQRREDLEDTRGTEP... | nuclear mRNA surveillance poly(A)+ mRNA export from nucleus telomere maintenance chromosome, telomeric region; cytoplasm; cytoplasmic stress granule; cytosol; nucleus; P-body chromatin binding mRNA binding single-stranded telomeric DNA binding Saccharomyces cerevisiae 3D-structure Chromosome Cytoplasm DNA-binding Nucl... |
protein catabolic process protein import into mitochondrial intermembrane space protein quality control for misfolded or incompletely synthesized proteins | i-AAA complex; mitochondrion | misfolded protein binding | Saccharomyces cerevisiae | Membrane Mitochondrion Mitochondrion inner membrane Reference proteome Transmembrane Transmembrane helix | MAVFTPPSGN | MAVFTPPSGNSNSTDHTHTQDDHDKDDNDIKKFYIRPSLGLKLWGPLVPAPDNLPGLYTLITIQSAVGFFALWRLRRLYKLPPPRRIATGTHSDLSFGELPSEMIVNGKTKIKKDIADFPTLNRFSTTHGDIVLAPPPIIPRQSRFVSVRKLLWGLFGSLLLSQSLLELTRLNFLKYDPWCDEMKSVRDKKFFNNIVKYYHEGIDPTKIKVKDAMNGTPLSTNIPEVKQSVALARAQVEAQNPIIKWFGPLEYKPMSFNEYLNRMEFHLDMFEFFQNKRNIRENSIELINSISHNPQSSSTGLEGLSESKKLHLQNVEKR... | protein catabolic process protein import into mitochondrial intermembrane space protein quality control for misfolded or incompletely synthesized proteins i-AAA complex; mitochondrion misfolded protein binding Saccharomyces cerevisiae Membrane Mitochondrion Mitochondrion inner membrane Reference proteome Transmembrane... |
invasive growth in response to glucose limitation NAD biosynthesis via nicotinamide riboside salvage pathway pseudohyphal growth ubiquitin-dependent ERAD pathway | cytoplasm; nucleus | ATP binding ATP hydrolysis activity nicotinamide-nucleotide adenylyltransferase activity | Saccharomyces cerevisiae | ATP-binding Cytoplasm NAD Nucleotide-binding Nucleotidyltransferase Nucleus Pyridine nucleotide biosynthesis Reference proteome Transferase | MKKTFEQFRK | MKKTFEQFRKSNLLFQVLKGPQHLECQKLFVLDSSFNPPHLAHFQLLSQTIKNFKLKDTRSHVLLLLAVNNADKLPKPASFPTRLEMMCLFADYLQEKLPQSVVSVGLTVFSKFIDKDKILHEQFVKGCSADIGYLVGFDTIARIFDEKYYHPLKISDVMESFMSGSQLYCLARGDCHLSAESQLRYASDILEGKFEPVIPREWGARIHVMQNDYPALRNVSSSEIRNKLKNGQVESLKDELPLCIYDYLINNKTIFD | invasive growth in response to glucose limitation NAD biosynthesis via nicotinamide riboside salvage pathway pseudohyphal growth ubiquitin-dependent ERAD pathway cytoplasm; nucleus ATP binding ATP hydrolysis activity nicotinamide-nucleotide adenylyltransferase activity Saccharomyces cerevisiae ATP-binding Cytoplasm NA... |
fungal-type cell wall organization GPI anchor biosynthetic process protein mannosylation protein processing ubiquitin-dependent ERAD pathway | endoplasmic reticulum; endoplasmic reticulum membrane; glycosylphosphatidylinositol-mannosyltransferase I complex | mannosyltransferase activity | Saccharomyces cerevisiae | Endoplasmic reticulum Glycoprotein GPI-anchor biosynthesis Membrane Reference proteome Transmembrane Transmembrane helix | MVTRHRVTVL | MVTRHRVTVLYNAPEDIGNHMRQNDTHLTVRGGSGVVLQQRWLLERTGSLDKSFTRITWRPRADLARSLSVIENELSAGFSVYSNSSDVPERFITNPVYNSFHSEKFDIEQYLPPEVDLNLSWNPEDFTYDISVEPTQIQIVEYRLLKQGEEFTIARVKDEKLEVGVFFVDASDESDVDIGGIRCNWRMDDGKMERCQKTSLLYKQGHIAYNHSTTTTSLYLNEPIGLHPKIMIDLTDFEERPKCMYLMHLQLPLELFIDKFQSSPLLLFGEDDLELPEYSLRDKAWGSESIFELKAGTMNEVTLHTRYIEPSNNKGDKL... | fungal-type cell wall organization GPI anchor biosynthetic process protein mannosylation protein processing ubiquitin-dependent ERAD pathway endoplasmic reticulum; endoplasmic reticulum membrane; glycosylphosphatidylinositol-mannosyltransferase I complex mannosyltransferase activity Saccharomyces cerevisiae Endoplasmi... |
maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) rRNA methylation | nucleolus; nucleus; preribosome, large subunit precursor | rRNA (guanine) methyltransferase activity rRNA (guanosine-2'-O-)-methyltransferase activity rRNA (uridine-2'-O-)-methyltransferase activity | Saccharomyces cerevisiae | 3D-structure Coiled coil Methyltransferase Nucleus Phosphoprotein Reference proteome Ribosome biogenesis rRNA processing S-adenosyl-L-methionine Transferase | MGKTQKKNSK | MGKTQKKNSKGRLDRYYYLAKEKGYRARSSFKIIQINEKYGHFLEKSKVVIDLCAAPGSWCQVASKLCPVNSLIIGVDIVPMKPMPNVITFQSDITTEDCRSKLRGYMKTWKADTVLHDGAPNVGLGWVQDAFTQSQLTLQALKLAVENLVVNGTFVTKIFRSKDYNKLIWVFQQLFEKVEATKPPASRNVSAEIFVVCKGFKAPKRLDPRLLDPKEVFEELPDGQQNMESKIYNPEKKVRKRQGYEEGDNLLYHETSILDFVRTEDPISMLGEMNKFTIDENDHEWKILKKLKQTTDEFRSCIEDLKVLGKKDFKMILR... | maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) rRNA methylation nucleolus; nucleus; preribosome, large subunit precursor rRNA (guanine) methyltransferase activity rRNA (guanosine-2'-O-)-me... |
karyogamy involved in conjugation with cellular fusion meiotic cell cycle mRNA methylation positive regulation of transcription by RNA polymerase II | cytoplasm; cytosol; nucleus; RNA N6-methyladenosine methyltransferase complex | DNA-binding transcription factor activity mRNA binding | Saccharomyces cerevisiae | Cytoplasm Karyogamy Meiosis Nucleus Reference proteome | MAFQDPTYDQ | MAFQDPTYDQNKSRHINNSHLQGPNQETIEMKSKHVSFKPSRDFHTNDYSNNYIHGKSLPQQHVTNIENRVDGYPKLQKLFQAKAKQINQFATTPFGCKIGIDSIVPTLNHWIQNENLTFDVVMIGCLTENQFIYPILTQLPLDRLISKPGFLFIWANSQKINELTKLLNNEIWAKKFRRSEELVFVPIDKKSPFYPGLDQDDETLMEKMQWHCWMCITGTVRRSTDGHLIHCNVDTDLSIETKDTTNGAVPSHLYRIAENFSTATRRLHIIPARTGYETPVKVRPGWVIVSPDVMLDNFSPKRYKEEIANLGSNIPLKN... | karyogamy involved in conjugation with cellular fusion meiotic cell cycle mRNA methylation positive regulation of transcription by RNA polymerase II cytoplasm; cytosol; nucleus; RNA N6-methyladenosine methyltransferase complex DNA-binding transcription factor activity mRNA binding Saccharomyces cerevisiae Cytoplasm Ka... |
endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of SSU-rRNA ribosomal small subunit biogenesis rRNA processing | 90S preribosome; nucleolus; nucleoplasm; preribosome, small subunit precursor; small-subunit processome | RNA binding | Saccharomyces cerevisiae | 3D-structure Nucleus Reference proteome Ribonucleoprotein Ribosome biogenesis RNA-binding rRNA processing | MVSTHNRDKP | MVSTHNRDKPWDTDDIDKWKIEEFKEEDNASGQPFAEESSFMTLFPKYRESYLKTIWNDVTRALDKHNIACVLDLVEGSMTVKTTRKTYDPAIILKARDLIKLLARSVPFPQAVKILQDDMACDVIKIGNFVTNKERFVKRRQRLVGPNGNTLKALELLTKCYILVQGNTVSAMGPFKGLKEVRRVVEDCMKNIHPIYHIKELMIKRELAKRPELANEDWSRFLPMFKKRNVARKKPKKIRNVEKKVYTPFPPAQLPRKVDLEIESGEYFLSKREKQMKKLNEQKEKQMEREIERQEERAKDFIAPEEEAYKPNQN | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of SSU-rRNA ribosomal small subunit biogenesis rRNA processing 90S preribosome; nucleolus; nucleoplasm; preribosome, small subunit precursor; small-subunit proce... |
vacuole inheritance | fungal-type vacuole membrane; Myo2p-Vac17p-Vac8p transport complex | protein-membrane adaptor activity | Saccharomyces cerevisiae | 3D-structure Acetylation Membrane Phosphoprotein Reference proteome Vacuole | MATQALEDIT | MATQALEDITERLLIRSQEAILQLDLWIQRQQRSSICQTTDQESLDKLSQQYNQYMSQLNSLYVRSESVRDKLSKEQQRRLITEDNEHQRIEDLVREFQDITLRLNELATVPNEAPNDSPQSQSTRSSLGSFQPRPLKIIERQRLCMVTPSKPPKKSVGFNPINEVDCPSKTNSLPCSPKKQPARNRTLRAAKSHDTGLNKSKKPSSSDTYESFFKNRQRLSLTFFDEMDDEDFDSDQDTIILPNISTPPHVGVTAKGAEFEPLRRYNSHESILSNKPAPSKSLNLGSFSASFFRPSNPTFGTSISNVQVNCHPTVAATM... | vacuole inheritance fungal-type vacuole membrane; Myo2p-Vac17p-Vac8p transport complex protein-membrane adaptor activity Saccharomyces cerevisiae 3D-structure Acetylation Membrane Phosphoprotein Reference proteome Vacuole MATQALEDIT MATQALEDITERLLIRSQEAILQLDLWIQRQQRSSICQTTDQESLDKLSQQYNQYMSQLNSLYVRSESVRDKLSKEQQRRLITEDN... |
ATP export endosome to lysosome transport late endosome to vacuole transport negative regulation of protein polyubiquitination protein modification process protein targeting to membrane protein targeting to vacuole protein transport reticulophagy ubiquitin-dependent protein catabolic process via the multivesicular body... | cytoplasmic side of plasma membrane; cytosol; endosome; ESCRT I complex; late endosome membrane | ubiquitin binding | Saccharomyces cerevisiae | 3D-structure Coiled coil Cytoplasm Endosome Membrane Protein transport Reference proteome Transport | MSANGKISVP | MSANGKISVPEAVVNWLFKVIQPIYNDGRTTFHDSLALLDNFHSLRPRTRVFTHSDGTPQLLLSIYGTISTGEDGSSPHSIPVIMWVPSMYPVKPPFISINLENFDMNTISSSLPIQEYIDSNGWIALPILHCWDPAAMNLIMVVQELMSLLHEPPQDQAPSLPPKPNTQLQQEQNTPPLPPKPKSPHLKPPLPPPPPPQPASNALDLMDMDNTDISPTNHHEMLQNLQTVVNELYREDVDYVADKILTRQTVMQESIARFHEIIAIDKNHLRAVEQAIEQTMHSLNAQIDVLTANRAKVQQFSSTSHVDDEDVNSIAVA... | ATP export endosome to lysosome transport late endosome to vacuole transport negative regulation of protein polyubiquitination protein modification process protein targeting to membrane protein targeting to vacuole protein transport reticulophagy ubiquitin-dependent protein catabolic process via the multivesicular body... |
branched-chain amino acid biosynthetic process isoleucine biosynthetic process valine biosynthetic process | acetolactate synthase complex; mitochondrial nucleoid; mitochondrion | acetolactate synthase regulator activity enzyme regulator activity | Saccharomyces cerevisiae | 3D-structure Amino-acid biosynthesis Branched-chain amino acid biosynthesis Direct protein sequencing Mitochondrion Reference proteome Transit peptide | MLRSLLQSGH | MLRSLLQSGHRRVVASSCATMVRCSSSSTSALAYKQMHRHATRPPLPTLDTPSWNANSAVSSIIYETPAPSRQPRKQHVLNCLVQNEPGVLSRVSGTLAARGFNIDSLVVCNTEVKDLSRMTIVLQGQDGVVEQARRQIEDLVPVYAVLDYTNSEIIKRELVMARISLLGTEYFEDLLLHHHTSTNAGAADSQELVAEIREKQFHPANLPASEVLRLKHEHLNDITNLTNNFGGRVVDISETSCIVELSAKPTRISAFLKLVEPFGVLECARSGMMALPRTPLKTSTEEAADEDEKISEIVDISQLPPG | branched-chain amino acid biosynthetic process isoleucine biosynthetic process valine biosynthetic process acetolactate synthase complex; mitochondrial nucleoid; mitochondrion acetolactate synthase regulator activity enzyme regulator activity Saccharomyces cerevisiae 3D-structure Amino-acid biosynthesis Branched-chain... |
acetate transport ammonium transmembrane transport meiotic cell cycle monoatomic ion transport nitrogen utilization transmembrane transport | mitochondrion; plasma membrane; vacuolar membrane | acetate transmembrane transporter activity ammonium transmembrane transporter activity | Saccharomyces cerevisiae | Ammonia transport Cell membrane Ion transport Meiosis Membrane Reference proteome Transmembrane Transmembrane helix Transport Vacuole | MSDKEQTSGN | MSDKEQTSGNTDLENAPAGYYSSHDNDVNGVAEDERPSHDSLGKIYTGGDNNEYIYIGRQKFLKSDLYQAFGGTLNPGLAPAPVHKFANPAPLGLSAFALTTFVLSMFNARAQGITVPNVVVGCAMFYGGLVQLIAGIWEIALENTFGGTALCSYGGFWLSFAAIYIPWFGILEAYEDNESDLNNALGFYLLGWAIFTFGLTVCTMKSTVMFFLLFFLLALTFLLLSIGHFANRLGVTRAGGVLGVVVAFIAWYNAYAGVATKQNSYVLARPFPLPSTERVIF | acetate transport ammonium transmembrane transport meiotic cell cycle monoatomic ion transport nitrogen utilization transmembrane transport mitochondrion; plasma membrane; vacuolar membrane acetate transmembrane transporter activity ammonium transmembrane transporter activity Saccharomyces cerevisiae Ammonia transport... |
double-strand break repair double-strand break repair via nonhomologous end joining | nucleus | DNA binding DNA-directed DNA polymerase activity metal ion binding | Saccharomyces cerevisiae | Direct protein sequencing DNA damage DNA repair DNA-directed DNA polymerase Magnesium Metal-binding Nucleotidyltransferase Nucleus Reference proteome Transferase | MSLKGKFFAF | MSLKGKFFAFLPNPNTSSNKFFKSILEKKGATIVSSIQNCLQSSRKEVVILIEDSFVDSDMHLTQKDIFQREAGLNDVDEFLGKIEQSGIQCVKTSCITKWVQNDKFAFQKDDLIKFQPSIIVISDNADDGQSSTDKESEISTDVESERNDDSNNKDMIQASKPLKRLLQGDKGRASLVTDKTKYKNNELIIGALKRLTKKYEIEGEKFRARSYRLAKQSMENCDFNVRSGEEAHTKLRNIGPSIAKKIQVILDTGVLPGLNDSVGLEDKLKYFKNCYGIGSEIAKRWNLLNFESFCVAAKKDPEEFVSDWTILFGWSYY... | double-strand break repair double-strand break repair via nonhomologous end joining nucleus DNA binding DNA-directed DNA polymerase activity metal ion binding Saccharomyces cerevisiae Direct protein sequencing DNA damage DNA repair DNA-directed DNA polymerase Magnesium Metal-binding Nucleotidyltransferase Nucleus Refe... |
actin cortical patch assembly budding cell bud growth cell cycle endocytosis positive regulation of endocytosis septin cytoskeleton organization unidimensional cell growth | cell division site; cellular bud neck; cellular bud neck septin ring; cellular bud tip; cytoplasm; endocytic patch; endocytic vesicle; mating projection base; mating projection tip; plasma membrane; prospore membrane; Syp1 complex | enzyme inhibitor activity identical protein binding | Saccharomyces cerevisiae | 3D-structure Cell cycle Endocytosis Isopeptide bond Phosphoprotein Reference proteome Ubl conjugation | MTEQRTKYAD | MTEQRTKYADSILTTKSPYEATETIRIRLSQVKLLNKDFYLLFKELANLKRNYAQQLRKIIAENEDITKILNAQMIESNVLTPQEMSAFRFNSLGELRNVWDTVIEELKSDLKSSTEYYNTLDQQVVRELKESVENNTSWRESKDLHSKLSKNAASIEHYSKNNENSSHLEEARRQWDQQSPYLFELFETIDYNRLDTLKNCMLRFQTSFSDYLLNTTKECETVMTKFLAFEPQSEIDRFAKDASQYNFQLSSSSKEVVPNNASPASATGARPVSVSNGAANTEREKKSPQKDKRKSAFGNIGHRLASASSSLTHNDLMN... | actin cortical patch assembly budding cell bud growth cell cycle endocytosis positive regulation of endocytosis septin cytoskeleton organization unidimensional cell growth cell division site; cellular bud neck; cellular bud neck septin ring; cellular bud tip; cytoplasm; endocytic patch; endocytic vesicle; mating projec... |
endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosomal small subunit export from nucleus rRNA (guanine-N7)-methylation | cytoplasm; nucleolus; nucleus; tRNA methyltransferase complex | rRNA (guanine) methyltransferase activity | Saccharomyces cerevisiae | 3D-structure Cytoplasm Methyltransferase Nucleus Reference proteome rRNA processing S-adenosyl-L-methionine Transferase | MSRPEELAPP | MSRPEELAPPEIFYNDSEAHKYTGSTRVQHIQAKMTLRALELLNLQPCSFILDIGCGSGLSGEILTQEGDHVWCGLDISPSMLATGLSRELEGDLMLQDMGTGIPFRAGSFDAAISISAIQWLCNADTSYNDPKQRLMRFFNTLYAALKKGGKFVAQFYPKNDDQVDDILQSAKVAGFSGGLVVDDPESKKNKKYYLVLSSGAPPQGEEQVNLDGVTMDEENVNLKKQLRQRLKGGKDKESAKSFILRKKELMKRRGRKVAKDSKFTGRKRRHRF | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosomal small subunit export from nucleus rRNA (guanine-N7)-methylation cytoplasm; nucleolus; nucleus; tRNA methyltransferase complex rRNA (guanine) methyltransferase act... |
endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-... | 90S preribosome; cytoplasm; nucleolus; nucleoplasm; Pwp2p-containing subcomplex of 90S preribosome; small-subunit processome | mRNA binding | Saccharomyces cerevisiae | 3D-structure Nucleus Phosphoprotein Reference proteome Repeat Ribonucleoprotein Ribosome biogenesis rRNA processing WD repeat | MKSDFKFSNL | MKSDFKFSNLLGTVYRQGNITFSDDGKQLLSPVGNRVSVFDLINNKSFTFEYEHRKNIAAIDLNKQGTLLISIDEDGRAILVNFKARNVLHHFNFKEKCSAVKFSPDGRLFALASGRFLQIWKTPDVNKDRQFAPFVRHRVHAGHFQDITSLTWSQDSRFILTTSKDLSAKIWSVDSEEKNLAATTFNGHRDYVMGAFFSHDQEKIYTVSKDGAVFVWEFTKRPSDDDDNESEDDDKQEEVDISKYSWRITKKHFFYANQAKVKCVTFHPATRLLAVGFTSGEFRLYDLPDFTLIQQLSMGQNPVNTVSVNQTGEWLAFG... | endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-... |
cellular response to amino acid starvation GCN2-mediated signaling negative regulation of kinase activity negative regulation of protein phosphorylation negative regulation of protein-containing complex assembly regulation of translational initiation | cytoplasm; nucleus | actin monomer binding polysome binding protein kinase inhibitor activity ribosome binding | Saccharomyces cerevisiae | 3D-structure Actin-binding Cytoplasm Isopeptide bond Nucleus Reference proteome Repressor Stress response Translation regulation Ubl conjugation | MDDDHEQLVE | MDDDHEQLVEELEAVEAIYPDLLSKKQEDGSIIVVKVPQHEYMTLQISFPTHYPSEEAPNVIEVGVCTSLAKRDLYDTKYLQHLFQEVMDSVFHRGSVCLFDFLTELDGVLYVEPEEETEPVQQSDIPTDPFEGWTASDPITDRGSTFMAFAAHVTSEEQAFAMLDLLKTDSKMRKANHVMSAWRIKQDGSAATYQDSDDDGETAAGSRMLHLITIMDVWNVIVVVARWFGGAHIGPDRFKHINSTAREAVVRAGFDS | cellular response to amino acid starvation GCN2-mediated signaling negative regulation of kinase activity negative regulation of protein phosphorylation negative regulation of protein-containing complex assembly regulation of translational initiation cytoplasm; nucleus actin monomer binding polysome binding protein kin... |
autophagy macroautophagy membrane disassembly multivesicular body membrane disassembly neutral lipid catabolic process pexophagy phosphatidylserine catabolic process piecemeal microautophagy of the nucleus vacuolar protein processing | endoplasmic reticulum; membrane; multivesicular body membrane; vacuolar lumen | phospholipase activity triglyceride lipase activity | Saccharomyces cerevisiae | Autophagy Endosome Glycoprotein Hydrolase Lipid degradation Lipid metabolism Membrane Reference proteome Signal-anchor Transmembrane Transmembrane helix | MLHKSPSRKR | MLHKSPSRKRFASPLHLGCILTLTVLCLIAYYFALPDYLSVGKSSSRGAMDQKSDGTFRLKSIYRHGVGANHRLHQRLEVTPEVISAAGMLYQETTTQGQDFEDQEPLWTTNAEYATTNPFDFEFELRRMPLLMKRMKERDPEFIESYIYGETYMTEEEEHAMWIDDDIVAPNITDRGTVVSLALMSSNAYVRIPQTGDWRNVTEPWNETEPEDFGWDGDGIRGHVFYNEVENIVVLSIKGTSAQGLPGSGEDETTGNDKINDNLLFSCCCARVSYLWTTVCDCYVKSYICDESCLEKELRRKDRFYSAVVDIYKGVLKE... | autophagy macroautophagy membrane disassembly multivesicular body membrane disassembly neutral lipid catabolic process pexophagy phosphatidylserine catabolic process piecemeal microautophagy of the nucleus vacuolar protein processing endoplasmic reticulum; membrane; multivesicular body membrane; vacuolar lumen phosphol... |
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