Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
|---|---|---|---|---|---|---|---|
angiotensin maturation basement membrane disassembly cellular response to glucose stimulus cytokine precursor processing extracellular matrix disassembly midbrain development positive regulation of angiogenesis protein catabolic process regulation of inflammatory response | collagen-containing extracellular matrix; cytoplasm; cytoplasmic ribonucleoprotein granule; cytosol; extracellular region; extracellular space; intracellular membrane-bounded organelle; secretory granule | endopeptidase activity peptide binding serine-type endopeptidase activity serine-type peptidase activity | Homo sapiens | 3D-structure Alternative splicing Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Secreted Serine protease Signal Zymogen | MLLLPLPLLL | MLLLPLPLLLFLLCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQAN | angiotensin maturation basement membrane disassembly cellular response to glucose stimulus cytokine precursor processing extracellular matrix disassembly midbrain development positive regulation of angiogenesis protein catabolic process regulation of inflammatory response collagen-containing extracellular matrix; cytop... |
cellular response to cholesterol cellular response to low-density lipoprotein particle stimulus cholesterol biosynthetic process cholesterol homeostasis cholesterol metabolic process epithelial cell differentiation lipid catabolic process medium-chain fatty acid metabolic process negative regulation of cholesterol stor... | cytoplasm; endoplasmic reticulum; endoplasmic reticulum lumen; extracellular space; lipid droplet | carboxylesterase activity carboxylic ester hydrolase activity hydrolase activity, acting on ester bonds protein homodimerization activity sterol esterase activity | Mus musculus | Direct protein sequencing Disulfide bond Endoplasmic reticulum Glycoprotein Hydrolase Phosphoprotein Reference proteome Serine esterase Signal | MWLHALVWAS | MWLHALVWASLAVCPILGHSLLPPVVDTTQGKVLGKYISLEGFEQPVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNATSYPPMCSQDAGWAKILSDMFSTEKEILPLKISEDCLYLNIYSPADLTKSSQLPVMVWIHGGGLVIGGASPYNGLALSAHENVVVVTIQYRLGIWGLFSTGDEHSPGNWAHLDQLAALRWVQDNIANFGGNPDSVTIFGESSGGISVSVLVLSPLGKDLFHRAISESGVVINTNVGKKNIQAVNEIIATLSQCNDTSSAAMVQCLRQKTESELLEISGKLVQYNISLSTMIDGVVLPKAP... | cellular response to cholesterol cellular response to low-density lipoprotein particle stimulus cholesterol biosynthetic process cholesterol homeostasis cholesterol metabolic process epithelial cell differentiation lipid catabolic process medium-chain fatty acid metabolic process negative regulation of cholesterol stor... |
fatty acid beta-oxidation | mitochondrial matrix; mitochondrion | delta(3)-delta(2)-enoyl-CoA isomerase activity identical protein binding intramolecular oxidoreductase activity, transposing C=C bonds | Rattus norvegicus | 3D-structure Acetylation Direct protein sequencing Fatty acid metabolism Isomerase Lipid metabolism Mitochondrion Reference proteome Transit peptide | MALAAARRVL | MALAAARRVLLQAGSRLGRRGAVDGARRFSNKRVLVEKEGEAGIAVMKFKNPPVNSLSLEFLTEFVISLEKLENDKSIRGVILTSERPGIFSAGLDLMEMYGRNPAHYAEYWKAVQELWLRLYLSNLTLISAINGASPAGGCLMALTCDYRIMADNSKYTIGLNESLLGIVAPFWLKDNYVNTIGHRAAERALQLGTLFPPAEALKVGLVDEVVPEDQVHSKARSVMAKWFTIPDHSRQLTKSMMRKATADNLIKQREADIQNFTSFISRDSIQKSLHVYLEKLKQKKG | fatty acid beta-oxidation mitochondrial matrix; mitochondrion delta(3)-delta(2)-enoyl-CoA isomerase activity identical protein binding intramolecular oxidoreductase activity, transposing C=C bonds Rattus norvegicus 3D-structure Acetylation Direct protein sequencing Fatty acid metabolism Isomerase Lipid metabolism Mitoc... |
endosomal lumen acidification Golgi lumen acidification proton transmembrane transport vacuolar acidification | fungal-type vacuole membrane; Golgi membrane; membrane; proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase, V0 domain | P-type proton-exporting transporter activity proton-transporting ATPase activity, rotational mechanism | Saccharomyces cerevisiae | 3D-structure Hydrogen ion transport Ion transport Membrane Reference proteome Transmembrane Transmembrane helix Transport Vacuole | MNKESKDDDM | MNKESKDDDMSLGKFSFSHFLYYLVLIVVIVYGLYKLFTGHGSDINFGKFLLRTSPYMWANLGIALCVGLSVVGAAWGIFITGSSMIGAGVRAPRITTKNLISIIFCEVVAIYGLIIAIVFSSKLTVATAENMYSKSNLYTGYSLFWAGITVGASNLICGIAVGITGATAAISDAADSALFVKILVIEIFGSILGLLGLIVGLLMAGKASEFQ | endosomal lumen acidification Golgi lumen acidification proton transmembrane transport vacuolar acidification fungal-type vacuole membrane; Golgi membrane; membrane; proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase, V0 domain P-typ... |
chemical synaptic transmission dopamine uptake involved in synaptic transmission monoamine transport neuron cellular homeostasis neurotransmitter transport norepinephrine transport norepinephrine uptake response to pain response to xenobiotic stimulus sodium ion transmembrane transport | cell surface; membrane; neuron projection; neuronal cell body membrane; plasma membrane; presynaptic membrane | actin binding alpha-tubulin binding beta-tubulin binding dopamine:sodium symporter activity metal ion binding monoamine transmembrane transporter activity neurotransmitter transmembrane transporter activity neurotransmitter:sodium symporter activity norepinephrine:sodium symporter activity | Homo sapiens | Alternative splicing Cell membrane Disease variant Disulfide bond Glycoprotein Membrane Metal-binding Neurotransmitter transport Reference proteome Sodium Symport Transmembrane Transmembrane helix Transport | MLLARMNPQV | MLLARMNPQVQPENNGADTGPEQPLRARKTAELLVVKERNGVQCLLAPRDGDAQPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQYNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFSSFTLNLPWTDCGHTWNSPNCTDPKLLNGSVLGNHTKYSKYKFTPAAEFYERGVLHLHESSGIHDIGLPQWQLLLCLMVVVIVLYFSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYLHIDFYRLKEATVWIDAATQIFFSLG... | chemical synaptic transmission dopamine uptake involved in synaptic transmission monoamine transport neuron cellular homeostasis neurotransmitter transport norepinephrine transport norepinephrine uptake response to pain response to xenobiotic stimulus sodium ion transmembrane transport cell surface; membrane; neuron pr... |
adenohypophysis development cognition dopamine biosynthetic process dopamine catabolic process dopamine transport dopamine uptake dopamine uptake involved in synaptic transmission hyaloid vascular plexus regression lactation locomotory behavior monoamine transport neurotransmitter transport neurotransmitter uptake nore... | axon; axon terminus; cell surface; dopaminergic synapse; flotillin complex; membrane raft; neuron projection; neuronal cell body; neuronal cell body membrane; plasma membrane; postsynaptic membrane; presynaptic membrane | amine binding dopamine binding dopamine:sodium symporter activity heterocyclic compound binding metal ion binding monoamine transmembrane transporter activity neurotransmitter transmembrane transporter activity norepinephrine:sodium symporter activity protease binding protein phosphatase 2A binding protein-containing c... | Rattus norvegicus | Cell membrane Cell projection Disulfide bond Glycoprotein Membrane Metal-binding Neurotransmitter transport Reference proteome Sodium Symport Transmembrane Transmembrane helix Transport | MSKSKCSVGP | MSKSKCSVGPMSSVVAPAKESNAVGPREVELILVKEQNGVQLTNSTLINPPQTPVEAQERETWSKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELALGQFNREGAAGVWKICPVLKGVGFTVILISFYVGFFYNVIIAWALHYFFSSFTMDLPWIHCNNTWNSPNCSDAHASNSSDGLGLNDTFGTTPAAEYFERGVLHLHQSRGIDDLGPPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAMDGIRAYLSVDFYRLCEASVWIDAATQVCFS... | adenohypophysis development cognition dopamine biosynthetic process dopamine catabolic process dopamine transport dopamine uptake dopamine uptake involved in synaptic transmission hyaloid vascular plexus regression lactation locomotory behavior monoamine transport neurotransmitter transport neurotransmitter uptake nore... |
associative learning chloride transmembrane transport gamma-aminobutyric acid import inorganic anion import across plasma membrane learning memory negative regulation of synaptic transmission, GABAergic neurotransmitter reuptake positive regulation of gamma-aminobutyric acid secretion response to calcium ion response t... | axon; cell surface; GABA-ergic synapse; neuronal cell body; plasma membrane; postsynaptic membrane; presynaptic membrane | amino acid:sodium symporter activity gamma-aminobutyric acid transmembrane transporter activity gamma-aminobutyric acid:sodium:chloride symporter activity identical protein binding metal ion binding sodium:chloride symporter activity | Rattus norvegicus | 3D-structure Cell membrane Cell projection Direct protein sequencing Disulfide bond Glycoprotein Membrane Metal-binding Neurotransmitter transport Phosphoprotein Reference proteome Sodium Symport Synapse Transmembrane Transmembrane helix Transport | MATDNSKVAD | MATDNSKVADGQISTEVSEAPVASDKPKTLVVKVQKKAGDLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWKQCDNPWNTDRCFSNYSLVNTTNMTSAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWVLVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDS... | associative learning chloride transmembrane transport gamma-aminobutyric acid import inorganic anion import across plasma membrane learning memory negative regulation of synaptic transmission, GABAergic neurotransmitter reuptake positive regulation of gamma-aminobutyric acid secretion response to calcium ion response t... |
inorganic cation transmembrane transport serotonin receptor signaling pathway | axon; cleavage furrow; glutamatergic synapse; neuron projection; neuronal cell body; postsynaptic membrane; presynaptic membrane; serotonin-activated cation-selective channel complex; synapse | acetylcholine-gated monoatomic cation-selective channel activity identical protein binding ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential serotonin binding serotonin-gated monoatomic cation channel activity | Mus musculus | 3D-structure Alternative splicing Cell membrane Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MRLCIPQVLL | MRLCIPQVLLALFLSMLTAPGEGSRRRATQARDTTQPALLRLSDHLLANYKKGVRPVRDWRKPTTVSIDVIMYAILNVDEKNQVLTTYIWYRQYWTDEFLQWTPEDFDNVTKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVHHRGEVQNYKPLQLVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINITLWRSPEEVRSDKSIFINQGEWELLEVFPQFKEFSIDISNSYAEMKFYVIIRRRPLFYAVSLLLPSIFLMVVDIVGFCLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMAL... | inorganic cation transmembrane transport serotonin receptor signaling pathway axon; cleavage furrow; glutamatergic synapse; neuron projection; neuronal cell body; postsynaptic membrane; presynaptic membrane; serotonin-activated cation-selective channel complex; synapse acetylcholine-gated monoatomic cation-selective ch... |
ethanol oxidation retinoic acid metabolic process retinol metabolic process | cytosol | alcohol dehydrogenase activity, zinc-dependent NAD-retinol dehydrogenase activity zinc ion binding | Gallus gallus | Acetylation Cytoplasm Direct protein sequencing Metal-binding NAD Oxidoreductase Reference proteome Zinc | MSTVGKVIKC | MSTVGKVIKCKAAVLWEANKPFSLEEVEVAPPKAHEVRIKIVATGICRSDDHVVTGALAMPFPIILGHEAAGVIESVGEKVTSLKPGDAVIPLFVPQCGECRSCLSTKGNLCIKNDLSSSPTGLMADGTTRFTCKGKAIHHFVGTSTFTEYTVVHETAAAKIDSAAPLEKVCLIGCGFSTGYGAVLQTAKVEAGSTCAVFGLGGVGLSVVMGCKAAGASRIIAVDINKDKFAKAKELGATECINPKDFKKPIHEVLTEMTGQGVDYSFEVIGRIETMTAALASCHNNYGVSVIVGVPPAAQKISFDPMLIFSGRTWKGSV... | ethanol oxidation retinoic acid metabolic process retinol metabolic process cytosol alcohol dehydrogenase activity, zinc-dependent NAD-retinol dehydrogenase activity zinc ion binding Gallus gallus Acetylation Cytoplasm Direct protein sequencing Metal-binding NAD Oxidoreductase Reference proteome Zinc MSTVGKVIKC MSTVGKV... |
cell adhesion defense response immune response negative regulation of viral life cycle positive regulation of gene expression positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding positive regulation of type III interferon production | cytosol; extracellular space; membrane | cytokine activity | Homo sapiens | Alternative splicing Cytokine Reference proteome Secreted Signal | MCFPKVLSDD | MCFPKVLSDDMKKLKARMVMLLPTSAQGLGAWVSACDTEDTVGHLGPWRDKDPALWCQLCLSSQHQAIERFYDKMQNAESGRGQVMSSLAELEDDFKEGYLETVAAYYEEQHPELTPLLEKERDGLRCRGNRSPVPDVEDPATEEPGESFCDKVMRWFQAMLQRLQTWWHGVLAWVKEKVVALVHAVQALWKQFQSFCCSLSELFMSSFQSYGAPRGDKEELTPQKCSEPQSSK | cell adhesion defense response immune response negative regulation of viral life cycle positive regulation of gene expression positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding positive regulation of type III interferon production cytosol; extracellular space; membrane cytokine act... |
actin crosslink formation actin filament bundle assembly parallel actin filament bundle assembly | cortical cytoskeleton; cytoplasm; filamentous actin; filopodium; intranuclear rod; phagocytic vesicle; pseudopodium | actin filament binding calcium ion binding | Dictyostelium discoideum | 3D-structure Actin-binding Calcium Direct protein sequencing Reference proteome | MAETKVAPNL | MAETKVAPNLTGIEQTKAGQSFTEKLSAEAMEFFCNVAKLPFSQQAVHFLNAYWAEVSKEAEFIYSVGWETIKYADMHCKGIQLVFKYDEGNDLDFDIALYFYEQLCKFCEDPKNKNYATTYPISQPQMLTALKRKQELREKVDVNFDGRVSFLEYLLYQYKDFANPADFCTRSMNHDEHPEIKKARLALEEVNKRIRAYEEEKARLTEESKIPGVKGLGATNMLAQIDSGPLKEQLNFALISAEAAVRTASKKYGGAAYSGGAGDAGAGSSAGAIWWMNRDLEEKKKRYGPQKK | actin crosslink formation actin filament bundle assembly parallel actin filament bundle assembly cortical cytoskeleton; cytoplasm; filamentous actin; filopodium; intranuclear rod; phagocytic vesicle; pseudopodium actin filament binding calcium ion binding Dictyostelium discoideum 3D-structure Actin-binding Calcium Dire... |
ATP synthesis coupled electron transport | plasma membrane; respirasome | copper ion binding cytochrome-c oxidase activity heme binding | Bacillus subtilis | Cell membrane Copper Electron transport Heme Iron Lipoprotein Membrane Metal-binding Palmitate Reference proteome Respiratory chain Signal Translocase Transmembrane Transmembrane helix Transport | MVKHWRLILL | MVKHWRLILLLALVPLLLSGCGKPFLSTLKPAGEVADKQYDLTVLSTLIMVVVVAVVSVIFFYVIVRFRRSRVGENTIPKQVEGNKFLEITWTVIPILLLIILVIPVVLYTLELADTSPMDKKGRKAEDALVVNVRANLYWWEFEYPDYGIITSQELIVPTDQRVYFNLKASDVKHSFWIPSVGGKLDTNTDNENKFFLTFDSKRSKEAGDMFFGKCAELCGPSHALMDFKVKTMSAKEFQGWTKEMKNYKSTAESDLAKQGEELFKEKNCLSCHAVEPNDKRAEAARTAPNLATFGERTKVAGVKEANKENVKAWLKDP... | ATP synthesis coupled electron transport plasma membrane; respirasome copper ion binding cytochrome-c oxidase activity heme binding Bacillus subtilis Cell membrane Copper Electron transport Heme Iron Lipoprotein Membrane Metal-binding Palmitate Reference proteome Respiratory chain Signal Translocase Transmembrane Trans... |
arachidonic acid secretion lipid catabolic process phospholipid metabolic process | extracellular region | calcium ion binding ion channel regulator activity phospholipase A2 activity toxin activity | Crotalus durissus terrificus | 3D-structure Blood coagulation cascade inhibiting toxin Calcium Direct protein sequencing Disulfide bond Hemostasis impairing toxin Hydrolase Ion channel impairing toxin Lipid degradation Lipid metabolism Metal-binding Neurotoxin Pharmaceutical Presynaptic neurotoxin Secreted Signal Toxin | MRALWIVAVL | MRALWIVAVLLVGVEGSLLQFNKMIKFETRKNAVPFYAFYGCYCGWGGQGRPKDATDRCCFVHDCCYGKLAKCNTKWDIYRYSLKSGYITCGKGTWCKEQICECDRVAAECLRRSLSTYKNEYMFYPDSRCREPSETC | arachidonic acid secretion lipid catabolic process phospholipid metabolic process extracellular region calcium ion binding ion channel regulator activity phospholipase A2 activity toxin activity Crotalus durissus terrificus 3D-structure Blood coagulation cascade inhibiting toxin Calcium Direct protein sequencing Disulf... |
DNA replication viral DNA genome replication | viral replication complex | ATP binding ATP hydrolysis activity DNA binding endonuclease activity helicase activity metal ion binding | Aleutian mink disease parvovirus | ATP-binding Covalent protein-DNA linkage DNA replication DNA-binding Endonuclease Helicase Host nucleus Hydrolase Magnesium Metal-binding Nuclease Nucleotide-binding Reference proteome Transcription Transcription regulation Viral DNA replication Viral genome packaging Viral release from host cell | MAQAQIDEQR | MAQAQIDEQRRLQDLYVQLKKEINDGEGVAWLFQQKTYTDKDNKPTKATPPLRTTSSDLRLAFDSIEENLTASNEHLTNNEINFCKLTLGKTLLLIDKHVKSHRWDSNKVNLIWQIEKGKTQQFHIHCCLGYFDKNEDPKDVQKSLGWFMKRLNKDLAVIYSNHHCDIQDIKDPEDRAKNLKVWIEDGPTKPYKYFNKQTKQDYNKPVHLRDYTFIYLFNKDKINTDSMDGYFAAGNGGIVDNLTNKERKTLRKMYLDEQSSDIMDANIDWEDGQDAPKVTDQTDSATTKTGTSLIWKSCATKVTSKKEVANPVQQPSKK... | DNA replication viral DNA genome replication viral replication complex ATP binding ATP hydrolysis activity DNA binding endonuclease activity helicase activity metal ion binding Aleutian mink disease parvovirus ATP-binding Covalent protein-DNA linkage DNA replication DNA-binding Endonuclease Helicase Host nucleus Hydro... |
cell division G2/M transition of mitotic cell cycle phosphorylation regulation of circadian rhythm rhythmic process | cytosol; nucleus | ATP binding cyclin-dependent protein serine/threonine kinase activity protein serine kinase activity protein serine/threonine kinase activity RNA polymerase II CTD heptapeptide repeat kinase activity | Xenopus laevis | ATP-binding Biological rhythms Cell cycle Cell division Kinase Mitosis Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MDEYTKIEKI | MDEYTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHPNIVCLLDVLMQDSRLYLIFEFLSMDLKKYLDSIPSGQYIDTMLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDNKGVIKLADFGLARAFGIPVRVYTHEVVTLWYRASEVLLGSVRYSTPVDVWSVGTIFAEIATKKPLFHGDSEIDQLFRIFRSLGTPNNEVWPEVESLQDYKNTFPKWKGGSLSSNVKNIDEDGLDLLSKMLVYDPAKRISARKAMLHPYFDDLDKSSLPANQIRN | cell division G2/M transition of mitotic cell cycle phosphorylation regulation of circadian rhythm rhythmic process cytosol; nucleus ATP binding cyclin-dependent protein serine/threonine kinase activity protein serine kinase activity protein serine/threonine kinase activity RNA polymerase II CTD heptapeptide repeat kin... |
chloride transmembrane transport | chloride channel complex; GABA-A receptor complex; neuron projection; postsynaptic membrane; synapse | chloride channel activity extracellular ligand-gated monoatomic ion channel activity GABA-A receptor activity neurotransmitter receptor activity | Gallus gallus | Alternative splicing Cell membrane Chloride Chloride channel Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MWTFQADRLS | MWTFQADRLSGIVSALAALCVACCAQSPSTGNISVVKEIVDKLLKGYDVRLRPDFGGNPVTVGMSIHISSIDQISEVNMDYTITMYFQQSWRDKRLAYNDLPLNLTLDNRVADQLWLPDTYFLNDKKSFLHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDQQNCTLEIESYGYTVDDIVFFWQGNDSAVTGMEVLELPQFTIIEQRLVSREVVFTTGSYLRLSLSFRIKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGVTTVLTMTTINTHLRETLPKIPYVKAIDVYLMGCFVFVFLAL... | chloride transmembrane transport chloride channel complex; GABA-A receptor complex; neuron projection; postsynaptic membrane; synapse chloride channel activity extracellular ligand-gated monoatomic ion channel activity GABA-A receptor activity neurotransmitter receptor activity Gallus gallus Alternative splicing Cell m... |
chemical synaptic transmission chloride transmembrane transport gamma-aminobutyric acid signaling pathway modulation of chemical synaptic transmission | chloride channel complex; GABA-A receptor complex; GABA-ergic synapse; glutamatergic synapse; neuron projection; plasma membrane; postsynaptic membrane; presynaptic membrane; synapse | chloride channel activity extracellular ligand-gated monoatomic ion channel activity GABA-A receptor activity identical protein binding ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential neurotransmitter receptor activity protein domain specific binding protein-contain... | Homo sapiens | 3D-structure Alternative splicing Cell membrane Chloride Chloride channel Disulfide bond Glycoprotein Ion channel Ion transport Membrane Postsynaptic cell membrane Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MLAVPNMRFG | MLAVPNMRFGIFLLWWGWVLATESRMHWPGREVHEMSKKGRPQRQRREVHEDAHKQVSPILRRSPDITKSPLTKSEQLLRIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITT... | chemical synaptic transmission chloride transmembrane transport gamma-aminobutyric acid signaling pathway modulation of chemical synaptic transmission chloride channel complex; GABA-A receptor complex; GABA-ergic synapse; glutamatergic synapse; neuron projection; plasma membrane; postsynaptic membrane; presynaptic memb... |
activation of cysteine-type endopeptidase activity involved in apoptotic process activation of plasma proteins involved in acute inflammatory response blood coagulation positive regulation of angiogenesis positive regulation of endothelial cell proliferation positive regulation of platelet-derived growth factor recepto... | cell surface; extracellular matrix; extracellular space; membrane | phospholipid binding | Oryctolagus cuniculus | 3D-structure Blood coagulation Disulfide bond Glycoprotein Hemostasis Lipoprotein Membrane Palmitate Reference proteome Repeat Signal Transmembrane Transmembrane helix | MAPPTRLQVP | MAPPTRLQVPRPGTAVPYTVLLGWLLAQVARAADTTGRAYNLTWKSTNFKTILEWEPKSIDHVYTVQISTRLENWKSKCFLTAETECDLTDEVVKDVGQTYMARVLSYPARNGNTTGFPEEPPFRNSPEFTPYLDTNLGQPTIQSFEQVGTKLNVTVQDARTLVRRNGTFLSLRAVFGKDLNYTLYYWRASSTGKKTATTNTNEFLIDVDKGENYCFSVQAVIPSRKRKQRSPESLTECTSREQGRAREMFFIIGAVVVVALLIIVLSVTVYKCRKARAGPSGKESSPLNIA | activation of cysteine-type endopeptidase activity involved in apoptotic process activation of plasma proteins involved in acute inflammatory response blood coagulation positive regulation of angiogenesis positive regulation of endothelial cell proliferation positive regulation of platelet-derived growth factor recepto... |
nitrogen fixation | periplasmic space | electron transfer activity heme binding metal ion binding | Bradyrhizobium diazoefficiens | Direct protein sequencing Electron transport Heme Iron Metal-binding Nitrogen fixation Periplasm Reference proteome Signal Transport | MHLHLRGICL | MHLHLRGICLVLAVASSSSSALAADAGHGADLAKRWCASCHVVANGQAVASADVPSFASVARRPDFSSEKLAFFLLDPHPKMPSFPLSRTEAGDIAAYIGSLRP | nitrogen fixation periplasmic space electron transfer activity heme binding metal ion binding Bradyrhizobium diazoefficiens Direct protein sequencing Electron transport Heme Iron Metal-binding Nitrogen fixation Periplasm Reference proteome Signal Transport MHLHLRGICL MHLHLRGICLVLAVASSSSSALAADAGHGADLAKRWCASCHVVANGQAVASA... |
cellular response to granulocyte macrophage colony-stimulating factor stimulus cellular response to interferon-alpha cellular response to interleukin-6 cellular response to lipopolysaccharide cellular response to tumor necrosis factor cellular response to type II interferon Fc receptor signaling pathway immune response... | extracellular region; ficolin-1-rich granule membrane; plasma membrane; specific granule membrane; tertiary granule membrane | IgA binding IgA receptor activity | Homo sapiens | 3D-structure Alternative splicing Cell membrane Disulfide bond Glycoprotein IgA-binding protein Immunoglobulin domain Membrane Receptor Reference proteome Repeat Secreted Signal Transmembrane Transmembrane helix | MDPKQTTLLC | MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVTGLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTDSIHQDYTTQNLIRMAVAGLVLVALLAILVENWHSHTALNKEASADVAEPSWSQQMCQPGLTFARTPSVCK | cellular response to granulocyte macrophage colony-stimulating factor stimulus cellular response to interferon-alpha cellular response to interleukin-6 cellular response to lipopolysaccharide cellular response to tumor necrosis factor cellular response to type II interferon Fc receptor signaling pathway immune response... |
acute-phase response animal organ regeneration cellular response to insulin stimulus cerebral cortex development male gonad development negative regulation of bone mineralization negative regulation of cell growth negative regulation of insulin receptor signaling pathway ossification positive regulation of bone resorpt... | collagen-containing extracellular matrix; extracellular matrix; extracellular region; extracellular space; protein-containing complex | cysteine-type endopeptidase inhibitor activity endopeptidase inhibitor activity kinase inhibitor activity receptor signaling protein tyrosine kinase inhibitor activity | Rattus norvegicus | Direct protein sequencing Disulfide bond Glycoprotein Phosphoprotein Reference proteome Repeat Secreted Signal | MKSLVLLLCF | MKSLVLLLCFAQLWSCQSAPQGAGLGFRELACDDPETEHVALIAVDYLNKHLLQGFRQILNQIDKVKVWSRRPFGEVYELEIDTLETTCHALDPTPLANCSVRQQAEHAVEGDCDFHILKQDGQFRVLHAQCHSTPDSAEDVRKFCPRCPILIRFNDTNVVHTVKTALAAFNAQNNGTYFKLVEISRAQNVPFPVSTLVEFVIAATDCTGQEVTDPAKCNLLAEKQYGFCKATLIHRLGGEEVSVACKLFQTQPQPANANPAGPAPTVGQAAPVAPPAGPPESVVVGPVAVPLGLPDHRTHHDLRHAFSPVASVESASGE... | acute-phase response animal organ regeneration cellular response to insulin stimulus cerebral cortex development male gonad development negative regulation of bone mineralization negative regulation of cell growth negative regulation of insulin receptor signaling pathway ossification positive regulation of bone resorpt... |
cell wall macromolecule catabolic process chitin catabolic process plant-type hypersensitive response polysaccharide catabolic process | vacuole | chitin binding chitinase activity | Nicotiana tabacum | Carbohydrate metabolism Chitin degradation Chitin-binding Direct protein sequencing Disulfide bond Glycosidase Hydrolase Hydroxylation Hypersensitive response Pathogenesis-related protein Plant defense Polysaccharide degradation Reference proteome Signal Vacuole | MRLREFTALS | MRLREFTALSSLLFSLLLLSASAEQCGSQAGGARCASGLCCSKFGWCGNTNDYCGPGNCQSQCPGGPTPPGGGDLGSIISSSMFDQMLKHRNDNACQGKGFYSYNAFINAARSFPGFGTSGDTTARKREIAAFFAQTSHETTGGWATAPDGPYAWGYCWLREQGSPGDYCTPSGQWPCAPGRKYFGRGPIQISHNYNYGPCGRAIGVDLLNNPDLVATDPVISFKSALWFWMTPQSPKPSCHDVIIGRWQPSSADRAANRLPGFGVITNIINGGLECGRGTDSRVQDRIGFYRRYCSILGVSPGDNLDCGNQRSFGNGLL... | cell wall macromolecule catabolic process chitin catabolic process plant-type hypersensitive response polysaccharide catabolic process vacuole chitin binding chitinase activity Nicotiana tabacum Carbohydrate metabolism Chitin degradation Chitin-binding Direct protein sequencing Disulfide bond Glycosidase Hydrolase Hydr... |
fatty acid biosynthetic process lipid oxidation oxylipin biosynthetic process | cytoplasm | iron ion binding linoleate 9S-lipoxygenase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | Glycine max | 3D-structure Cytoplasm Dioxygenase Fatty acid biosynthesis Fatty acid metabolism Iron Lipid biosynthesis Lipid metabolism Metal-binding Oxidoreductase Oxylipin biosynthesis Reference proteome | MFGIFDKGQK | MFGIFDKGQKIKGTVVLMPKNVLDFNAITSIGKGGVIDTATGILGQGVSLVGGVIDTATSFLGRNISMQLISATQTDGSGNGKVGKEVYLEKHLPTLPTLGARQDAFSIFFEWDASFGIPGAFYIKNFMTDEFFLVSVKLEDIPNHGTIEFVCNSWVYNFRSYKKNRIFFVNDTYLPSATPAPLLKYRKEELEVLRGDGTGKRKDFDRIYDYDVYNDLGNPDGGDPRPILGGSSIYPYPRRVRTGRERTRTDPNSEKPGEVYVPRDENFGHLKSSDFLTYGIKSLSHDVIPLFKSAIFQLRVTSSEFESFEDVRSLYEGG... | fatty acid biosynthetic process lipid oxidation oxylipin biosynthetic process cytoplasm iron ion binding linoleate 9S-lipoxygenase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Glycine max 3D-structure Cytoplasm Dioxygenase Fatty ... |
asymmetric cell division cytokinesis by cell plate formation DNA endoreduplication embryo development ending in seed dormancy gametophyte development guard mother cell cytokinesis guard mother cell differentiation meiotic cytokinesis phosphorylation pollen development positive regulation of cell population proliferatio... | cortical microtubule, transverse to long axis; cytoplasm; nucleus; preprophase band | ATP binding cyclin-dependent protein serine/threonine kinase activity kinase activity protein kinase activity protein serine kinase activity RNA polymerase II CTD heptapeptide repeat kinase activity | Arabidopsis thaliana | ATP-binding Cell cycle Cell division Cytoplasm Kinase Mitosis Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MDQYEKVEKI | MDQYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHSNIVKLQDVVHSEKRLYLVFEYLDLDLKKHMDSTPDFSKDLHMIKTYLYQILRGIAYCHSHRVLHRDLKPQNLLIDRRTNSLKLADFGLARAFGIPVRTFTHEVVTLWYRAPEILLGSHHYSTPVDIWSVGCIFAEMISQKPLFPGDSEIDQLFKIFRIMGTPYEDTWRGVTSLPDYKSAFPKWKPTDLETFVPNLDPDGVDLLSKMLLMDPTKRINARAALEHEYFKDLGGMP | asymmetric cell division cytokinesis by cell plate formation DNA endoreduplication embryo development ending in seed dormancy gametophyte development guard mother cell cytokinesis guard mother cell differentiation meiotic cytokinesis phosphorylation pollen development positive regulation of cell population proliferatio... |
defense response defense response to bacterium defense response to fungus hydrogen peroxide catabolic process pattern recognition receptor signaling pathway reactive oxygen species metabolic process response to light stimulus response to oxidative stress unidimensional cell growth | cytosol; extracellular region; plant-type cell wall; plant-type vacuole; secretory vesicle | heme binding lactoperoxidase activity metal ion binding peroxidase activity | Arabidopsis thaliana | Calcium Disulfide bond Glycoprotein Heme Hydrogen peroxide Iron Metal-binding Oxidoreductase Peroxidase Pyrrolidone carboxylic acid Reference proteome Secreted Signal Vacuole | MQFSSSSITS | MQFSSSSITSFTWTVLITVGCLMLCASFSDAQLTPTFYDTSCPTVTNIVRDTIVNELRSDPRIAGSILRLHFHDCFVNGCDASILLDNTTSFRTEKDALGNANSARGFPVIDRMKAAVERACPRTVSCADMLTIAAQQSVTLAGGPSWKVPLGRRDSLQAFLDLANANLPAPFFTLPQLKANFKNVGLDRPSDLVALSGAHTFGKNQCRFIMDRLYNFSNTGLPDPTLNTTYLQTLRGQCPRNGNQSVLVDFDLRTPLVFDNKYYVNLKEQKGLIQSDQELFSSPNATDTIPLVRAYADGTQTFFNAFVEAMNRMGNITP... | defense response defense response to bacterium defense response to fungus hydrogen peroxide catabolic process pattern recognition receptor signaling pathway reactive oxygen species metabolic process response to light stimulus response to oxidative stress unidimensional cell growth cytosol; extracellular region; plant-t... |
hydrogen peroxide catabolic process response to oxidative stress response to zinc ion | extracellular region; secretory vesicle; vacuole | heme binding lactoperoxidase activity metal ion binding | Arabidopsis thaliana | Calcium Disulfide bond Glycoprotein Heme Hydrogen peroxide Iron Metal-binding Oxidoreductase Peroxidase Pyrrolidone carboxylic acid Reference proteome Secreted Signal Vacuole | MGFSPSFSCS | MGFSPSFSCSAIGALILGCLLLQASNSNAQLRPDFYFGTCPFVFDIIGNIIVDELQTDPRIAASLLRLHFHDCFVRGCDASILLDNSTSFRTEKDAAPNANSARGFNVIDRMKVALERACPGRVSCADILTIASQISVLLSGGPWWPVPLGRRDSVEAFFALANTALPSPFFNLTQLKTAFADVGLNRTSDLVALSGGHTFGRAQCQFVTPRLYNFNGTNSPDPSLNPTYLVELRRLCPQNGNGTVLVNFDVVTPDAFDSQYYTNLRNGKGLIQSDQELFSTPGADTIPLVNQYSSDMSVFFRAFIDAMIRMGNLRPLTG... | hydrogen peroxide catabolic process response to oxidative stress response to zinc ion extracellular region; secretory vesicle; vacuole heme binding lactoperoxidase activity metal ion binding Arabidopsis thaliana Calcium Disulfide bond Glycoprotein Heme Hydrogen peroxide Iron Metal-binding Oxidoreductase Peroxidase Pyrr... |
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane suppression by virus of host tetherin activity suppression by virus of host type I interferon-mediated signaling pathway virion attachment to host cell | host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane | structural molecule activity | Human immunodeficiency virus type 2 subtype A | AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Inhibition of h... | MERGRNQLLI | MERGRNQLLIAILLASACLIYCRQQYVTVFYGVPAWKNASIPLFCATKNRDTWGTIQCLPDNDDYQEIPLNVTEAFDAWDNTITEQAIEDVWNLFETSIKPCVKLTPLCVAMKCNISTSDTTMIRTTTPSTAKEAPISDNSPCIRTNNCSGLEEEKIVKCHFNMTGLERDKKKQYNETWYSSDVVCDNSTDQTTNETTCYMNHCNTSVITESCDKHYWDAMRFRYCAPPGFAILRCNDTKYSGFAPNCSKVVASTCTRMMETQTSTWFGFNGTRAENRTYIYWHGKDNRTIISLNKHYNLSMYCRRPGNKTVVPITLMSG... | clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane suppression by virus of host tetherin activity suppression by virus of host type I interferon-mediated signaling pathway virion attachment to host cell host cell endosome membrane; host cell plasma membrane; membra... |
viral budding via host ESCRT complex | host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane | RNA binding structural molecule activity zinc ion binding | Human immunodeficiency virus type 2 subtype A | AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Phosphoprotein Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucleoprotein Viral release from hos... | MGARNSVLRG | MGARNSVLRGKKADELEKVRLRPGGKKKYKLKHIVWAANELDRFGLAESLLESKEGCQRILKVLDPLVPTGSENLKSLFNTVCVIWCIHAEEKVKDTEEAKRIALRHLAAETGTAEKMPDTSRPTAPPSGKGGNYPVQSIGGNYTHVPLSPRTLNAWVKLVEEKKFGAEVVPGFQALSEGCTPYDINQMLNCVGDHQAAMQIIREIINEEAADWDANHPIPGPLPAGQLRDPRGSDIAGTTSTVEEQIQWMFRAQNPVPVGNIYRRWIQIGLQKCVRMYNPTNILDIKQGPKESFQSYVDRFYKSLRAEQTDPAVKNWMT... | viral budding via host ESCRT complex host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane RNA binding structural molecule activity zinc ion binding Human immunodeficiency virus type 2 subtype A AIDS Capsid protein Host cell membrane Host cytoplasm Host e... |
dolichol biosynthetic process dolichol-linked oligosaccharide biosynthetic process | endoplasmic reticulum membrane; membrane | glycosyltransferase activity identical protein binding metal ion binding UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity | Cricetulus griseus | Endoplasmic reticulum Glycoprotein Glycosyltransferase Magnesium Membrane Metal-binding Transferase Transmembrane Transmembrane helix | MWAFPELPLP | MWAFPELPLPLLVNLFGSLLGFVATVTLIPAFRSHFIAARLCGQDLNKLSRQQIPESQGVICGAVFLIILFCFIPFPFLNCFVEEQCKAFPHHEFVALIGALLAICCMIFLGFADDVLNLRWRHKLLLPTAASLPLLMVYFTNFGNTTIVVPKPFRWILGLHLDLGILYYVYMGLLAVFCTNAINILAGINGLEAGQSLVISASIIVFNLVELEGDYRDDHVFSLYFMIPFFFTTLGLLYHNWYPSQVFVGDTFCYFAGMTFAVVGILGHFSKTMLLFFIPQVFNFLYSLPQLLHAIPCPRHRIPRLNPKTGKLEMSYSK... | dolichol biosynthetic process dolichol-linked oligosaccharide biosynthetic process endoplasmic reticulum membrane; membrane glycosyltransferase activity identical protein binding metal ion binding UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity UDP-N-acetylglucosamine-lysosomal... |
intracellular signal transduction peptide catabolic process peptide metabolic process proteolysis | mitochondrial intermembrane space | metal ion binding metalloendopeptidase activity peptidase activity peptide binding | Rattus norvegicus | Acetylation Cytoplasm Direct protein sequencing Hydrolase Metal-binding Metalloprotease Phosphoprotein Protease Reference proteome Zinc | MKPPAACAGD | MKPPAACAGDVVDTVSPCSTVNHLRWDLSAQQIRALTTQLIEQTKCVYDRVGAQDFEDVSYESTLKALADVEVTYTVQRNILDFPQHVSPNKDIRAASTEADKKLSEFDVEMSMRQDVYQRVVWLQEKIPKDSLKPEAARYLERLIKLGRRNGLHLPQDTQEKIKNIKKRLSLLCIDFNKNLNEDTTFLPFTREELGGLPEDFLNSLEKTEDGKLKVTLKYPHYFPLLKKCHVPETRRLLEEAFNCRCKEENCAILKELVSLRAQKSNLLGFRTHADYVLEMNMAKTSQTVATFLDELARKLKPLGEQERAVILELKEAE... | intracellular signal transduction peptide catabolic process peptide metabolic process proteolysis mitochondrial intermembrane space metal ion binding metalloendopeptidase activity peptidase activity peptide binding Rattus norvegicus Acetylation Cytoplasm Direct protein sequencing Hydrolase Metal-binding Metalloprotease... |
antimicrobial humoral response cell-cell junction maintenance collagen catabolic process mature conventional dendritic cell differentiation membrane protein ectodomain proteolysis negative regulation of phagocytosis neutrophil extravasation positive regulation of cell population proliferation positive regulation of GTP... | azurophil granule lumen; cytosol; extracellular exosome; extracellular region; extracellular space; intracellular membrane-bounded organelle; plasma membrane; plasma membrane raft | enzyme binding serine-type endopeptidase activity serine-type peptidase activity signaling receptor binding | Homo sapiens | 3D-structure Cell membrane Collagen degradation Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Membrane Protease Reference proteome Secreted Serine protease Signal Zymogen | MAHRPPSPAL | MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRRVEAKGRP | antimicrobial humoral response cell-cell junction maintenance collagen catabolic process mature conventional dendritic cell differentiation membrane protein ectodomain proteolysis negative regulation of phagocytosis neutrophil extravasation positive regulation of cell population proliferation positive regulation of GTP... |
adaptive immune response cell surface receptor signaling pathway Fc-gamma receptor signaling pathway positive regulation of protein localization to cell surface protein complex oligomerization protein-containing complex assembly T cell receptor signaling pathway | alpha-beta T cell receptor complex; cytoplasm; Fc-gamma receptor III complex; Golgi apparatus; plasma membrane; T cell receptor complex | identical protein binding protein heterodimerization activity protein homodimerization activity protein tyrosine kinase binding transmembrane signaling receptor activity | Mus musculus | Adaptive immunity Alternative splicing Cell membrane Direct protein sequencing Immunity Membrane Phosphoprotein Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix | MKWKVSVLAC | MKWKVSVLACILHVRFPGAEAQSFGLLDPKLCYLLDGILFIYGVIITALYLRAKFSRSAETAANLQDPNQLYNELNLGRREEYDVLEKKRARDPEMGGKQQRRRNPQEGVYNALQKDKMAEAYSEIGTKGERRRGKGHDGLYQGLSTATKDTYDALHMQTLAPR | adaptive immune response cell surface receptor signaling pathway Fc-gamma receptor signaling pathway positive regulation of protein localization to cell surface protein complex oligomerization protein-containing complex assembly T cell receptor signaling pathway alpha-beta T cell receptor complex; cytoplasm; Fc-gamma r... |
proteolysis | cytoplasm; cytosol; outer membrane-bounded periplasmic space | carboxypeptidase activity metal ion binding metalloendopeptidase activity | Escherichia coli | 3D-structure Calcium Carboxypeptidase Cytoplasm Direct protein sequencing Hydrolase Metal-binding Metalloprotease Protease Reference proteome Zinc | MTTMNPFLVQ | MTTMNPFLVQSTLPYLAPHFDQIANHHYRPAFDEGMQQKRAEIAAIALNPQMPDFNNTILALEQSGELLTRVTSVFFAMTAAHTNDELQRLDEQFSAELAELANDIYLNGELFARVDAVWQRRESLGLDSESIRLVEVIHQRFVLAGAKLAQADKAKLKVLNTEAATLTSQFNQRLLAANKSGGLVVNDIAQLAGMSEQEIALAAEAAREKGLDNKWLIPLLNTTQQPALAEMRDRATREKLFIAGWTRAEKNDANDTRAIIQRLVEIRAQQATLLGFPHYAAWKIADQMAKTPEAALNFMREIVPAARQRASDELASIQ... | proteolysis cytoplasm; cytosol; outer membrane-bounded periplasmic space carboxypeptidase activity metal ion binding metalloendopeptidase activity Escherichia coli 3D-structure Calcium Carboxypeptidase Cytoplasm Direct protein sequencing Hydrolase Metal-binding Metalloprotease Protease Reference proteome Zinc MTTMNPFLV... |
lipopolysaccharide core region biosynthetic process | cytosol; plasma membrane | ADP-heptose-lipopolysaccharide heptosyltransferase activity lipopolysaccharide heptosyltransferase activity | Escherichia coli | Cell inner membrane Cell membrane Direct protein sequencing Glycosyltransferase Lipopolysaccharide biosynthesis Membrane Reference proteome Transferase | MRVLIVKTSS | MRVLIVKTSSMGDVLHTLPALTDAQQAIPGIKFDWVVEEGFAQIPSWHAAVERVIPVAIRRWRKAWFSAPIKAERKAFREALQAENYDAVIDAQGLVKSAALVTRLAHGVKHGMDWQTAREPLASLFYNRKHHIAKQQHAVERTRELFAKSLGYSKPQTQGDYAIAQHFLTNLPTDAGEYAVFLHATTRDDKHWPEEHWRELIGLLADSGIRIKLPWGAPHEEERAKRLAEGFAYVEVLPKMSLEGVARVLAGAKFVVSVDTGLSHLTAALDRPNITVYGPTDPGLIGGYGKNQMVCRAPRENLINLNSQAVLEKLSSL | lipopolysaccharide core region biosynthetic process cytosol; plasma membrane ADP-heptose-lipopolysaccharide heptosyltransferase activity lipopolysaccharide heptosyltransferase activity Escherichia coli Cell inner membrane Cell membrane Direct protein sequencing Glycosyltransferase Lipopolysaccharide biosynthesis Membra... |
fatty acid biosynthetic process malonyl-CoA biosynthetic process negative regulation of fatty acid biosynthetic process | acetyl-CoA carboxylase complex; cytoplasm; cytosol | acetyl-CoA carboxylase activity ATP binding biotin carboxylase activity metal ion binding protein homodimerization activity | Escherichia coli | 3D-structure ATP-binding Biotin Direct protein sequencing Fatty acid biosynthesis Fatty acid metabolism Ligase Lipid biosynthesis Lipid metabolism Magnesium Manganese Metal-binding Nucleotide-binding Reference proteome | MLDKIVIANR | MLDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLLADETVCIGPAPSVKSYLNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVEEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFENGEFYFIEMNTRIQVEHPVTEMITGVDLIKEQLRIAAGQP... | fatty acid biosynthetic process malonyl-CoA biosynthetic process negative regulation of fatty acid biosynthetic process acetyl-CoA carboxylase complex; cytoplasm; cytosol acetyl-CoA carboxylase activity ATP binding biotin carboxylase activity metal ion binding protein homodimerization activity Escherichia coli 3D-struc... |
histidine biosynthetic process methionine biosynthetic process purine nucleotide biosynthetic process tetrahydrofolate interconversion | cytosol | methenyltetrahydrofolate cyclohydrolase activity methylenetetrahydrofolate dehydrogenase (NADP+) activity protein homodimerization activity | Escherichia coli | 3D-structure Amino-acid biosynthesis Direct protein sequencing Histidine biosynthesis Hydrolase Methionine biosynthesis Multifunctional enzyme NADP One-carbon metabolism Oxidoreductase Purine biosynthesis Reference proteome | MAAKIIDGKT | MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNPASQIYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDTLNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTLQACVEYHDPQDE | histidine biosynthetic process methionine biosynthetic process purine nucleotide biosynthetic process tetrahydrofolate interconversion cytosol methenyltetrahydrofolate cyclohydrolase activity methylenetetrahydrofolate dehydrogenase (NADP+) activity protein homodimerization activity Escherichia coli 3D-structure Amino-a... |
protein maturation protein-containing complex assembly | ATPase complex | lyase activity | Escherichia coli | 3D-structure Direct protein sequencing Lyase Reference proteome | MNNIQLAHGS | MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGV... | protein maturation protein-containing complex assembly ATPase complex lyase activity Escherichia coli 3D-structure Direct protein sequencing Lyase Reference proteome MNNIQLAHGS MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKL... |
DNA damage response | cytoplasm; cytosol | GTP binding GTPase activity identical protein binding transition metal ion binding | Escherichia coli | 3D-structure Chaperone GTP-binding Hydrolase Metal-binding Nucleotide-binding Reference proteome Zinc | MNPIAVTLLT | MNPIAVTLLTGFLGAGKTTLLRHILNEQHGYKIAVIENEFGEVSVDDQLIGDRATQIKTLTNGCICCSRSNELEDALLDLLDNLDKGNIQFDRLVIECTGMADPGPIIQTFFSHEVLCQRYLLDGVIALVDAVHADEQMNQFTIAQSQVGYADRILLTKTDVAGEAEKLHERLARINARAPVYTVTHGDIDLGLLFNTNGFMLEENVVSTKPRFHFIADKQNDISSIVVELDYPVDISEVSRVMENLLLESADKLLRYKGMLWIDGEPNRLLFQGVQRLYSADWDRPWGDEKPHSTMVFIGIQLPEEEIRAAFAGLRK | DNA damage response cytoplasm; cytosol GTP binding GTPase activity identical protein binding transition metal ion binding Escherichia coli 3D-structure Chaperone GTP-binding Hydrolase Metal-binding Nucleotide-binding Reference proteome Zinc MNPIAVTLLT MNPIAVTLLTGFLGAGKTTLLRHILNEQHGYKIAVIENEFGEVSVDDQLIGDRATQIKTLTNGCICCS... |
fatty acid biosynthetic process | cytoplasm | holo- synthase activity magnesium ion binding transferase activity | Escherichia coli | 3D-structure Cytoplasm Direct protein sequencing Fatty acid biosynthesis Fatty acid metabolism Lipid biosynthesis Lipid metabolism Magnesium Metal-binding Reference proteome Transferase | MAILGLGTDI | MAILGLGTDIVEIARIEAVIARSGDRLARRVLSDNEWAIWKTHHQPVRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVFNDELGKPRLRLWGEALKLAEKLGVANMHVTLADERHYACATVIIES | fatty acid biosynthetic process cytoplasm holo- synthase activity magnesium ion binding transferase activity Escherichia coli 3D-structure Cytoplasm Direct protein sequencing Fatty acid biosynthesis Fatty acid metabolism Lipid biosynthesis Lipid metabolism Magnesium Metal-binding Reference proteome Transferase MAILGLGT... |
cell cycle cell division cell wall organization peptidoglycan biosynthetic process peptidoglycan metabolic process proteolysis regulation of cell shape response to antibiotic | periplasmic space; plasma membrane | carboxypeptidase activity endopeptidase activity penicillin binding serine-type carboxypeptidase activity serine-type D-Ala-D-Ala carboxypeptidase activity serine-type endopeptidase activity | Escherichia coli | 3D-structure Antibiotic resistance Cell cycle Cell division Cell shape Cell wall biogenesis/degradation Direct protein sequencing Hydrolase Peptidoglycan synthesis Periplasm Reference proteome Signal | MRFSRFIIGL | MRFSRFIIGLTSCIAFSVQAANVDEYITQLPAGANLALMVQKVGASAPAIDYHSQQMALPASTQKVITALAALIQLGPDFRFTTTLETKGNVENGVLKGDLVARFGADPTLKRQDIRNMVATLKKSGVNQIDGNVLIDTSIFASHDKAPGWPWNDMTQCFSAPPAAAIVDRNCFSVSLYSAPKPGDMAFIRVASYYPVTMFSQVRTLPRGSAEAQYCELDVVPGDLNRFTLTGCLPQRSEPLPLAFAVQDGASYAGAILKDELKQAGITWSGTLLRQTQVNEPGTVVASKQSAPLHDLLKIMLKKSDNMIADTVFRMIGH... | cell cycle cell division cell wall organization peptidoglycan biosynthetic process peptidoglycan metabolic process proteolysis regulation of cell shape response to antibiotic periplasmic space; plasma membrane carboxypeptidase activity endopeptidase activity penicillin binding serine-type carboxypeptidase activity seri... |
DNA duplex unwinding DNA recombination DNA repair response to radiation | cytosol; Holliday junction helicase complex | ATP binding ATP hydrolysis activity DNA binding DNA helicase activity | Escherichia coli | ATP-binding DNA damage DNA recombination DNA repair DNA-binding Helicase Hydrolase Nucleotide-binding Reference proteome | MKGRLLDAVP | MKGRLLDAVPLSSLTGVGAALSNKLAKINLHTVQDLLLHLPLRYEDRTHLYPIGELLPGVYATVEGEVLNCNISFGGRRMMTCQISDGSGILTMRFFNFSAAMKNSLAAGRRVLAYGEAKRGKYGAEMIHPEYRVQGDLSTPELQETLTPVYPTTEGVKQATLRKLTDQALDLLDTCAIEELLPPELSQGMMTLPEALRTLHRPPPTLQLSDLETGQHPAQRRLILEELLAHNLSMLALRAGAQRFHAQPLSANDTLKNKLLAALPFKPTGAQARVVAEIERDMALDVPMMRLVQGDVGSGKTLVAALAALRAIAHGKQV... | DNA duplex unwinding DNA recombination DNA repair response to radiation cytosol; Holliday junction helicase complex ATP binding ATP hydrolysis activity DNA binding DNA helicase activity Escherichia coli ATP-binding DNA damage DNA recombination DNA repair DNA-binding Helicase Hydrolase Nucleotide-binding Reference prote... |
cellular response to nitrosative stress nitric oxide catabolic process response to nitrosative stress response to toxic substance | cytoplasm | FAD binding fatty acid binding heme binding hydroperoxide reductase activity metal ion binding nitric oxide dioxygenase activity oxygen binding oxygen carrier activity | Escherichia coli | 3D-structure Cytoplasm Detoxification Direct protein sequencing FAD Flavoprotein Heme Iron Metal-binding NAD NADP Oxidoreductase Oxygen transport Reference proteome Transport | MLDAQTIATV | MLDAQTIATVKATIPLLVETGPKLTAHFYDRMFTHNPELKEIFNMSNQRNGDQREALFNAIAAYASNIENLPALLPAVEKIAQKHTSFQIKPEQYNIVGEHLLATLDEMFSPGQEVLDAWGKAYGVLANVFINREAEIYNENASKAGGWEGTRDFRIVAKTPRSALITSFELEPVDGGAVAEYRPGQYLGVWLKPEGFPHQEIRQYSLTRKPDGKGYRIAVKREEGGQVSNWLHNHANVGDVVKLVAPAGDFFMAVADDTPVTLISAGVGQTPMLAMLDTLAKAGHTAQVNWFHAAENGDVHAFADEVKELGQSLPRFTA... | cellular response to nitrosative stress nitric oxide catabolic process response to nitrosative stress response to toxic substance cytoplasm FAD binding fatty acid binding heme binding hydroperoxide reductase activity metal ion binding nitric oxide dioxygenase activity oxygen binding oxygen carrier activity Escherichia ... |
brain segmentation canonical Wnt signaling pathway cell fate commitment cerebellum morphogenesis fourth ventricle development hindbrain development midbrain-hindbrain boundary development neuron differentiation | extracellular space | cytokine activity frizzled binding | Danio rerio | Developmental protein Differentiation Disulfide bond Extracellular matrix Glycoprotein Lipoprotein Neurogenesis Reference proteome Secreted Signal Wnt signaling pathway | MRVLALLLAV | MRVLALLLAVKAACVLLVSSLTGTGAVNNSGRWWGIVNVASSGNLLTNSKNVQLVLDPSLALLSRRQRKLIRQNPGILHAIAAGLHTAIKECKWQFRNRRWNCPTTHSPNVFGKIVNRGCRETAFVFAITSAGVTHAVARSCSEGAIESCTCDYRRRGPGGPDWHWGGCSDNVEFGRMFGREFVDSSERGRDLRYLTNLHNNEAGRMTVASEMQQECKCHGMSGSCTVRTCWMRLPSFRLVGDYLKDRFDGASRVVYANKGSNRASHRADPRHLEPENPAHKLPSSRDLVYFEKSPNFCSYNGKTGTHGTSGRTCNSSSP... | brain segmentation canonical Wnt signaling pathway cell fate commitment cerebellum morphogenesis fourth ventricle development hindbrain development midbrain-hindbrain boundary development neuron differentiation extracellular space cytokine activity frizzled binding Danio rerio Developmental protein Differentiation Dis... |
cGMP biosynthetic process cGMP-mediated signaling female pregnancy negative regulation of systemic arterial blood pressure neuropeptide signaling pathway receptor guanylyl cyclase signaling pathway regulation of blood pressure vasodilation | cell projection; cytoplasm; extracellular space; perikaryon | hormone activity hormone receptor binding | Sus scrofa | Cell projection Direct protein sequencing Disulfide bond Hormone Phosphoprotein Reference proteome Secreted Signal Vasoactive Vasodilator | MSSFTITVSF | MSSFTITVSFLLVLVFQFPGQTRANPVYGSVSNADLMDFKNLLDHLEDKMPLEDEAMPPQVLSEQNEEVGAPLSPLLEVPPWTGEVNPAQRDGGALGRGPWDASDRSALLKSKLRALLAAPRSLRRSSCFGGRMDRIGAQSGLGCNSFRY | cGMP biosynthetic process cGMP-mediated signaling female pregnancy negative regulation of systemic arterial blood pressure neuropeptide signaling pathway receptor guanylyl cyclase signaling pathway regulation of blood pressure vasodilation cell projection; cytoplasm; extracellular space; perikaryon hormone activity hor... |
autophagosome assembly insulin catabolic process insulin receptor recycling lipoprotein catabolic process positive regulation of apoptotic process protein catabolic process proteolysis regulation of establishment of protein localization response to nutrient levels | endosome lumen; endosome membrane; extracellular space; GABA-ergic synapse; lysosomal membrane; lysosome; melanosome; membrane raft; presynaptic endosome | aspartic-type endopeptidase activity aspartic-type peptidase activity endopeptidase activity hydrolase activity peptidase activity peptide binding | Rattus norvegicus | 3D-structure Aspartyl protease Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Lysosome Protease Reference proteome Secreted Signal Zymogen | MQTPGVLLLI | MQTPGVLLLILGLLDASSSALIRIPLRKFTSIRRTMTEVGGSVEDLILKGPITKYSMQSSPRTKEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQKAIGAVPLIQGEY... | autophagosome assembly insulin catabolic process insulin receptor recycling lipoprotein catabolic process positive regulation of apoptotic process protein catabolic process proteolysis regulation of establishment of protein localization response to nutrient levels endosome lumen; endosome membrane; extracellular space;... |
aerobic respiration cellular detoxification of hydrogen peroxide cellular response to growth factor stimulus cholesterol metabolic process hemoglobin metabolic process hydrogen peroxide catabolic process kidney development negative regulation of apoptotic process positive regulation of cell division positive regulation... | catalase complex; cytoplasm; cytosol; extracellular space; intracellular membrane-bounded organelle; mitochondrion; peroxisomal matrix; peroxisomal membrane; peroxisome; protein-containing complex | aminoacylase activity antioxidant activity catalase activity enzyme binding heme binding identical protein binding metal ion binding NADP binding oxidoreductase activity, acting on peroxide as acceptor protein homodimerization activity | Mus musculus | Acetylation Direct protein sequencing Heme Hydrogen peroxide Iron Metal-binding Mitogen NADP Oxidoreductase Peroxidase Peroxisome Phosphoprotein Reference proteome | MSDSRDPASD | MSDSRDPASDQMKQWKEQRASQRPDVLTTGGGNPIGDKLNIMTAGSRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITRYSKAKVFEHIGKRTPIAVRFSTVTGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDAILFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNADGEAVYCKFHYKTDQGIKNLPVGEAGRLAQEDPDYGLRDLFNAIANGNYPSWTFYIQVMTFKEAETFPFNPFDLTKVWPHKDYPLIPVGKLVLNK... | aerobic respiration cellular detoxification of hydrogen peroxide cellular response to growth factor stimulus cholesterol metabolic process hemoglobin metabolic process hydrogen peroxide catabolic process kidney development negative regulation of apoptotic process positive regulation of cell division positive regulation... |
negative regulation of adenylate cyclase activity | dendrite membrane; dendritic spine; excitatory synapse; membrane raft; plasma membrane; postsynaptic density; postsynaptic recycling endosome membrane | adenylate cyclase binding beta-2 adrenergic receptor binding calmodulin binding GABA receptor binding glutamate receptor binding molecular adaptor activity protein kinase A regulatory subunit binding | Bos taurus | Calmodulin-binding Endosome Lipoprotein Membrane Palmitate Phosphoprotein Reference proteome Synapse | MEITVSEIQV | MEITVSEIQVESKDETRSAEVRPQDERQEEKASMLCFKRRKKAAKAMKPKASSKAADAAKKCPPEARASDQPQRPGGAWDSIKRLVTRRKRSESSKQQKPFKAKLQSEINAEDANPSKKKAKSRLKIPCIKFSKGEKRSNHSKIIEDSDRSVKVQEAENLVTKTQTQSDDQATKSKSPQDVREDVSQKGDDEVCESNVNNSITSPGEKVISVELELDMGHSAIQRGTLILEKDTEMLEEKQSIQPQHVSPLEASDTEQELPVGSEVPPSSAVPDQQILEEARNGVLESGPDWKEHESREIVVEESKPKDTELSQELDFQE... | negative regulation of adenylate cyclase activity dendrite membrane; dendritic spine; excitatory synapse; membrane raft; plasma membrane; postsynaptic density; postsynaptic recycling endosome membrane adenylate cyclase binding beta-2 adrenergic receptor binding calmodulin binding GABA receptor binding glutamate recepto... |
negative regulation of transcription by RNA polymerase II regulation of cytokine production regulation of immune system process | nucleoplasm | DNA-binding transcription factor activity DNA-binding transcription repressor activity, RNA polymerase II-specific metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding | Homo sapiens | DNA-binding Isopeptide bond Metal-binding Nucleus Reference proteome Repeat Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | MDTASHSLVL | MDTASHSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFIHQTSECIKIQPTDIQPDIFSYLLHIMYTGKGPKQIVDHSRLEEGIRFLHADYLSHIATEMNQVFSPETVQSSNLYGIQISTTQKTVVKQGLEVKEAPSSNSGNRAAVQGDHPQLQLSLAIGLDDGTADQQRACPATQALEEHQKPPVSIKQERCDPESVISQSHPSPSSEVTGPTFTENSVKIHLCHYCGERFDSRSNLRQHLHTHVSGSLPFGVPASILESNDLGEVHPLNENSEALECRRLSSFIVKENEQQPDHTNRGTTEPL... | negative regulation of transcription by RNA polymerase II regulation of cytokine production regulation of immune system process nucleoplasm DNA-binding transcription factor activity DNA-binding transcription repressor activity, RNA polymerase II-specific metal ion binding RNA polymerase II cis-regulatory region sequenc... |
DNA replication initiation DNA strand elongation involved in DNA replication DNA unwinding involved in DNA replication double-strand break repair via break-induced replication mitotic DNA replication initiation pre-replicative complex assembly involved in nuclear cell cycle DNA replication premeiotic DNA replication si... | chromosome, telomeric region; CMG complex; cytoplasm; DNA replication preinitiation complex; MCM complex; nuclear pre-replicative complex; nuclear replication fork; nucleoplasm; nucleus; replication fork protection complex | ATP binding ATP hydrolysis activity chromatin binding DNA replication origin binding helicase activity MCM complex binding single-stranded DNA binding | Saccharomyces cerevisiae | 3D-structure ATP-binding DNA replication DNA-binding Helicase Hydrolase Nucleotide-binding Nucleus Phosphoprotein Reference proteome | MEGSTGFDGD | MEGSTGFDGDATTFFAPDAVFGDRVRRFQEFLDTFTSYRDSVRSIQVYNSNNAANYNDDQDDADERDLLGDDDGDDLEKEKKAASSTSLNILPHRIIISLDDLREFDRSFWSGILVEPAYFIPPAEKALTDLADSMDDVPHPNASAVSSRHPWKLSFKGSFGAHALSPRTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYRDYTDATTTLTTRIPTPAIYPTEDTEGNKLTTEYGYSTFIDHQRITVQEMPEMAPAGQLPRSIDVILDDDLVDKTKPGDRVNVVGVFKSLGAGGMNQSNSNTLIGFKTL... | DNA replication initiation DNA strand elongation involved in DNA replication DNA unwinding involved in DNA replication double-strand break repair via break-induced replication mitotic DNA replication initiation pre-replicative complex assembly involved in nuclear cell cycle DNA replication premeiotic DNA replication si... |
ascospore formation Golgi to plasma membrane protein transport Golgi to vacuole transport Golgi vesicle budding negative regulation of phosphatidylcholine biosynthetic process negative regulation of phosphatidylglycerol biosynthetic process phosphatidylinositol metabolic process phospholipid transport | cytoplasm; cytosol; Golgi apparatus; Golgi membrane | phosphatidylcholine transporter activity phosphatidylinositol transfer activity | Saccharomyces cerevisiae | 3D-structure Cytoplasm Direct protein sequencing Golgi apparatus Isopeptide bond Membrane Phosphoprotein Protein transport Reference proteome Transport Ubl conjugation | MVTQQEKEFL | MVTQQEKEFLESYPQNCPPDALPGTPGNLDSAQEKALAELRKLLEDAGFIERLDDSTLLRFLRARKFDVQLAKEMFENCEKWRKDYGTDTILQDFHYDEKPLIAKFYPQYYHKTDKDGRPVYFEELGAVNLHEMNKVTSEERMLKNLVWEYESVVQYRLPACSRAAGHLVETSCTIMDLKGISISSAYSVMSYVREASYISQNYYPERMGKFYIINAPFGFSTAFRLFKPFLDPVTVSKIFILGSSYQKELLKQIPAENLPVKFGGKSEVDESKGGLYLSDIGPWRDPKYIGPEGEAPEAFSMK | ascospore formation Golgi to plasma membrane protein transport Golgi to vacuole transport Golgi vesicle budding negative regulation of phosphatidylcholine biosynthetic process negative regulation of phosphatidylglycerol biosynthetic process phosphatidylinositol metabolic process phospholipid transport cytoplasm; cytoso... |
branched-chain amino acid catabolic process leucine biosynthetic process lipid metabolic process valine biosynthetic process | cytosol; mitochondrion | branched-chain-amino-acid transaminase activity identical protein binding L-isoleucine transaminase activity L-leucine transaminase activity L-leucine:2-oxoglutarate aminotransferase activity L-valine transaminase activity | Mus musculus | Acetylation Amino-acid biosynthesis Aminotransferase Branched-chain amino acid biosynthesis Cytoplasm Lipid metabolism Pyridoxal phosphate Reference proteome Transferase | MKDCSNGCSA | MKDCSNGCSAPFAGERGSEEVAETFRAKDLIITPATVLKEKPDPDSLVFGATFTDHMLTVEWSSASGWEKPHIKPFGNLPIHPAASVLHYAVELFEGLKAFRGVDNKIRLFRPDLNMDRMCRSAVRTTLPMFDKEELLKCILQLLQIDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPSKALLFVILSPVGPYFSSGSFTPVSLWANPKYIRAWKGGTGDCKMGGNYGASLLAQCEAVENGCQQVLWLYGKDNQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRQSILELAQQWGEFKVCERHLTMDDLATAL... | branched-chain amino acid catabolic process leucine biosynthetic process lipid metabolic process valine biosynthetic process cytosol; mitochondrion branched-chain-amino-acid transaminase activity identical protein binding L-isoleucine transaminase activity L-leucine transaminase activity L-leucine:2-oxoglutarate aminot... |
DNA catabolic process | extracellular region | endonuclease activity metal ion binding nucleic acid binding | Penicillium citrinum | 3D-structure Direct protein sequencing Disulfide bond Endonuclease Glycoprotein Hydrolase Metal-binding Nuclease Secreted Zinc | WGALGHATVA | WGALGHATVAYVAQHYVSPEAASWAQGILGSSSSSYLASIASWADEYRLTSAGKWSASLHFIDAEDNPPTNCNVDYERDCGSSGCSISAIANYTQRVSDSSLSSENHAEALRFLVHFIGDMTQPLHDEAYAVGGNKINVTFDGYHDNLHSDWDTYMPQKLIGGHALSDAESWAKTLVQNIESGNYTAQAIGWIKGDNISEPITTATRWASDANALVCTVVMPHGAAALQTGDLYPTYYDSVIDTIELQIAKGGYRLANWINEIHGSEIAK | DNA catabolic process extracellular region endonuclease activity metal ion binding nucleic acid binding Penicillium citrinum3D-structure Direct protein sequencing Disulfide bond Endonuclease Glycoprotein Hydrolase Metal-binding Nuclease Secreted Zinc WGALGHATVA WGALGHATVAYVAQHYVSPEAASWAQGILGSSSSSYLASIASWADEYRLTSAGKWSAS... |
biosynthetic process cellular response to insulin stimulus L-alanine catabolic process positive regulation of gluconeogenesis response to starvation | cytosol; extracellular exosome | L-alanine:2-oxoglutarate aminotransferase activity pyridoxal phosphate binding | Homo sapiens | Acetylation Aminotransferase Cytoplasm Direct protein sequencing Phosphoprotein Pyridoxal phosphate Reference proteome Transferase | MASSTGDRSQ | MASSTGDRSQAVRHGLRAKVLTLDGMNPRVRRVEYAVRGPIVQRALELEQELRQGVKKPFTEVIRANIGDAQAMGQRPITFLRQVLALCVNPDLLSSPNFPDDAKKRAERILQACGGHSLGAYSVSSGIQLIREDVARYIERRDGGIPADPNNVFLSTGASDAIVTVLKLLVAGEGHTRTGVLIPIPQYPLYSATLAELGAVQVDYYLDEERAWALDVAELHRALGQARDHCRPRALCVINPGNPTGQVQTRECIEAVIRFAFEERLFLLADEVYQDNVYAAGSQFHSFKKVLMEMGPPYAGQQELASFHSTSKGYMGEC... | biosynthetic process cellular response to insulin stimulus L-alanine catabolic process positive regulation of gluconeogenesis response to starvation cytosol; extracellular exosome L-alanine:2-oxoglutarate aminotransferase activity pyridoxal phosphate binding Homo sapiens Acetylation Aminotransferase Cytoplasm Direct pr... |
D-xylose metabolic process | cytoplasm | identical protein binding magnesium ion binding xylose isomerase activity | Streptomyces rubiginosus | 3D-structure Carbohydrate metabolism Cytoplasm Isomerase Magnesium Metal-binding Xylose metabolism | MNYQPTPEDR | MNYQPTPEDRFTFGLWTVGWQGRDPFGDATRRALDPVESVRRLAELGAHGVTFHDDDLIPFGSSDSEREEHVKRFRQALDDTGMKVPMATTNLFTHPVFKDGGFTANDRDVRRYALRKTIRNIDLAVELGAETYVAWGGREGAESGGAKDVRDALDRMKEAFDLLGEYVTSQGYDIRFAIEPKPNEPRGDILLPTVGHALAFIERLERPELYGVNPEVGHEQMAGLNFPHGIAQALWAGKLFHIDLNGQNGIKYDQDLRFGAGDLRAAFWLVDLLESAGYSGPRHFDFKPPRTEDFDGVWASAAGCMRNYLILKERAAAF... | D-xylose metabolic process cytoplasm identical protein binding magnesium ion binding xylose isomerase activity Streptomyces rubiginosus3D-structure Carbohydrate metabolism Cytoplasm Isomerase Magnesium Metal-binding Xylose metabolism MNYQPTPEDR MNYQPTPEDRFTFGLWTVGWQGRDPFGDATRRALDPVESVRRLAELGAHGVTFHDDDLIPFGSSDSEREEHVKRF... |
viral entry into host cell virion attachment to host cell | host cell plasma membrane; membrane; viral envelope; virion membrane | host cell surface receptor binding | Canine distemper virus | 3D-structure Glycoprotein Hemagglutinin Host cell membrane Host membrane Host-virus interaction Membrane Signal-anchor Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Virion Virus entry into host cell | MLPYQDKVGA | MLPYQDKVGAFYKDNARANSTKLSLVTEGHGGRRPPYLLFVLLILLVGILALLAITGVRFHQVSTSNMEFSRLLKEDMEKSEAVHHQVIDVLTPLFKIIGDEIGLRLPQKLNEIKQFILQKTNFFNPNREFDFRDLHWCINPPSTVKVNFTNYCESIGIRKAIASAANPILLSALSGGRGDIFPPHRCSGATTSVGKVFPLSVSLSMSLISRTSEVINMLTAISDGVYGKTYLLVPDDIEREFDTREIRVFEIGFIKRWLNDMPLLQTTNYMVLPKNSKAKVCTIAVGELTLASLCVEESTVLLYHDSSGSQDGILVVTL... | viral entry into host cell virion attachment to host cell host cell plasma membrane; membrane; viral envelope; virion membrane host cell surface receptor binding Canine distemper virus 3D-structure Glycoprotein Hemagglutinin Host cell membrane Host membrane Host-virus interaction Membrane Signal-anchor Transmembrane T... |
mRNA splicing, via spliceosome pseudohyphal growth retrotransposition RNA catabolic process RNA splicing, via transesterification reactions sno(s)RNA metabolic process | cytoplasm; nucleus | iron ion binding manganese ion binding RNA binding RNA lariat debranching enzyme activity zinc ion binding | Saccharomyces cerevisiae | Cytoplasm Hydrolase Iron Manganese Metal-binding mRNA processing Nucleus Phosphoprotein Reference proteome RNA-binding Zinc | MTKLRIAVQG | MTKLRIAVQGCCHGQLNQIYKEVSRIHAKTPIDLLIILGDFQSIRDGQDFKSIAIPPKYQRLGDFISYYNNEIEAPVPTIFIGGNHESMRHLMLLPHGGYVAKNIFYMGYSNVIWFKGIRIGSLSGIWKEWDFNKQRPDWNDLENNNWKANIRNLYHVRISDIAPLFMIKHRIDIMLSHDWPNGVVYHGDTKHLLKLKPFFEQDIKEGKLGSPVTWQLLRDLRPQWWLSAHLHVRFMASIKHNKRSHEPPNKSTSKTKKNNNEIDLDLSSDEDERSGIMNCQEENEYDSKYGETRFLALDKCLPRRRWLEILEIEPDTSH... | mRNA splicing, via spliceosome pseudohyphal growth retrotransposition RNA catabolic process RNA splicing, via transesterification reactions sno(s)RNA metabolic process cytoplasm; nucleus iron ion binding manganese ion binding RNA binding RNA lariat debranching enzyme activity zinc ion binding Saccharomyces cerevisiae ... |
generation of precursor metabolites and energy mitochondrial electron transport, cytochrome c to oxygen mitochondrial respirasome assembly regulation of oxidative phosphorylation | mitochondrial respirasome; mitochondrial respiratory chain complex IV; mitochondrion | cytochrome-c oxidase activity | Homo sapiens | Direct protein sequencing Membrane Mitochondrion Mitochondrion inner membrane Oxidoreductase Reference proteome Transit peptide Transmembrane Transmembrane helix | MQALRVSQAL | MQALRVSQALIRSFSSTARNRFQNRVREKQKLFQEDNDIPLYLKGGIVDNILYRVTMTLCLGGTVYSLYSLGWASFPRN | generation of precursor metabolites and energy mitochondrial electron transport, cytochrome c to oxygen mitochondrial respirasome assembly regulation of oxidative phosphorylation mitochondrial respirasome; mitochondrial respiratory chain complex IV; mitochondrion cytochrome-c oxidase activity Homo sapiens Direct protei... |
cellular respiration central nervous system development mitochondrial electron transport, cytochrome c to oxygen | mitochondrial inner membrane; mitochondrial membrane; mitochondrial respiratory chain complex IV; mitochondrion; respiratory chain complex IV | cytochrome-c oxidase activity | Homo sapiens | 3D-structure Direct protein sequencing Membrane Mitochondrion Mitochondrion inner membrane Reference proteome Transit peptide Transmembrane Transmembrane helix | MFPLVKSALN | MFPLVKSALNRLQVRSIQQTMARQSHQKRTPDFHDKYGNAVLASGATFCIVTWTYVATQVGIEWNLSPVGRVTPKEWRNQ | cellular respiration central nervous system development mitochondrial electron transport, cytochrome c to oxygen mitochondrial inner membrane; mitochondrial membrane; mitochondrial respiratory chain complex IV; mitochondrion; respiratory chain complex IV cytochrome-c oxidase activity Homo sapiens 3D-structure Direct pr... |
alcohol biosynthetic process carotenoid biosynthetic process farnesyl diphosphate biosynthetic process geranyl diphosphate biosynthetic process geranylgeranyl diphosphate biosynthetic process isoprenoid biosynthetic process isoprenoid metabolic process mycotoxin biosynthetic process | cytoplasm | dimethylallyltranstransferase activity farnesyltranstransferase activity geranyltranstransferase activity metal ion binding prenyltransferase activity | Neurospora crassa | Alternative initiation Carotenoid biosynthesis Cytoplasm Isoprene biosynthesis Magnesium Metal-binding Reference proteome Transferase | MEHVTMAVTS | MEHVTMAVTSSSPGPAPLSLLSNNDDFIAPFNINTKFPSAIVPPRTSSNQPISVAIPSNRISSAGLAATQQAQTRKRKASVAQISLPSMLPTSFSPYTMAPQPPQPPPNPDRFATEDFFSPSRRTWSEEKEKVLTGPYDYLNGHPGKDIRSQMVKAFDAWLDVPSESLEVITKVISMLHTASLLVDDVEDNSVLRRGFPVAHSIFGIPQTINTSNYVYFYALQELQKLKNPKAVSIFSEELLNLHRGQGMDLFWRDTLTCPTEDDYLEMVSNKTGGLFRLGIKLMQAESRSPVDCVPLVNIIGLIFQIADDYHNLWNREY... | alcohol biosynthetic process carotenoid biosynthetic process farnesyl diphosphate biosynthetic process geranyl diphosphate biosynthetic process geranylgeranyl diphosphate biosynthetic process isoprenoid biosynthetic process isoprenoid metabolic process mycotoxin biosynthetic process cytoplasm dimethylallyltranstransfer... |
protein folding protein transport | membrane raft; plasma membrane | peptidyl-prolyl cis-trans isomerase activity | Bacillus subtilis | 3D-structure Cell membrane Isomerase Lipoprotein Membrane Palmitate Reference proteome Rotamase Signal | MKKIAIAAIT | MKKIAIAAITATSILALSACSSGDKEVIAKTDAGDVTKGELYTNMKKTAGASVLTQLVQEKVLDKKYKVSDKEIDNKLKEYKTQLGDQYTALEKQYGKDYLKEQVKYELLTQKAAKDNIKVTDADIKEYWEGLKGKIRASHILVADKKTAEEVEKKLKKGEKFEDLAKEYSTDSSASKGGDLGWFAKEGQMDETFSKAAFKLKTGEVSDPVKTQYGYHIIKKTEERGKYDDMKKELKSEVLEQKLNDNAAVQEAVQKVMKKADIEVKDKDLKDTFNTSSTSNSTSSSSSNSK | protein folding protein transport membrane raft; plasma membrane peptidyl-prolyl cis-trans isomerase activity Bacillus subtilis 3D-structure Cell membrane Isomerase Lipoprotein Membrane Palmitate Reference proteome Rotamase Signal MKKIAIAAIT MKKIAIAAITATSILALSACSSGDKEVIAKTDAGDVTKGELYTNMKKTAGASVLTQLVQEKVLDKKYKVSDKEIDNKL... |
epithelial cell differentiation iron-sulfur cluster assembly rRNA import into mitochondrion rRNA transport | mitochondrial matrix; mitochondrion | 5S rRNA binding sulfurtransferase activity thiosulfate sulfurtransferase activity | Rattus norvegicus | Acetylation Direct protein sequencing Glycoprotein Mitochondrion Phosphoprotein Reference proteome Repeat RNA-binding Transferase | MVHQVLYRAL | MVHQVLYRALVSTKWLAESIRSGKVGPSLRVLDASWYSPGTRQARKEYQERHVPGASFFDIEECRDTTSPYEMMLPSEAHFGDYVGNLGISNDTHVVVYDGDDLGSFYAPRVWWMFRVFGHRTVSVLNGGFRNWLKEGHPVTSEPSRPEPAVFKATLNRSLLKTYEQVLENLQSKRFQLVDSRAQGRYLGTQPEPDAVGLDSGHIRGSVNVPFMNFLTEDGFEKSPEELRAIFQDKKVDLSQPLIATCRKGVTACHIALAAYLCGKPDVAVYDGSWSEWFRRAPPETRVSQGKSGKA | epithelial cell differentiation iron-sulfur cluster assembly rRNA import into mitochondrion rRNA transport mitochondrial matrix; mitochondrion 5S rRNA binding sulfurtransferase activity thiosulfate sulfurtransferase activity Rattus norvegicus Acetylation Direct protein sequencing Glycoprotein Mitochondrion Phosphoprote... |
dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis epidermal growth factor receptor signaling pathway epithelial cell proliferation involved in mammary gland duct elongation ERBB2-EGFR signaling pathway G protein-coupled receptor signaling pathway glial cell proliferation mammary gla... | cell surface; cytoplasm; extracellular space; membrane; nucleus | cytokine activity epidermal growth factor receptor binding growth factor activity receptor ligand activity transmembrane receptor protein tyrosine kinase activator activity | Rattus norvegicus | Cytokine Direct protein sequencing Disulfide bond EGF-like domain Glycoprotein Growth factor Membrane Reference proteome Signal Transmembrane Transmembrane helix | MRTPSLSLAL | MRTPSLSLALSVLSLLVLGSGHYAAGLELNGTSSGKGEPSSGDHSAGGLVVSEVSTISEMPSGSELSTGDYDYSEEYDNEPQISGYIVDDSVRVEQVIKPKENKTEGEKSSEKPKRKKKGGKGGKGRRNRKKKKNPCAAKFQNFCIHGECRYIENLEVVTCHCHQDYFGERCGEKTMKTQKKDDSDLSKIALAAIIVFVSAVSVAAIGIITAVLLRKRFFREYEEAEERRRLRQENGTAHAIA | dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis epidermal growth factor receptor signaling pathway epithelial cell proliferation involved in mammary gland duct elongation ERBB2-EGFR signaling pathway G protein-coupled receptor signaling pathway glial cell proliferation mammary gla... |
anther dehiscence negative regulation of auxin mediated signaling pathway negative regulation of DNA-templated transcription plasmodesmata-mediated intercellular transport | cytoplasm; microtubule cytoskeleton; nucleus; plasmodesma | DNA-binding transcription factor activity, RNA polymerase II-specific protein homodimerization activity RNA binding sequence-specific DNA binding | Zea mays | Cell junction Cytoplasm DNA-binding Homeobox Nucleus Reference proteome RNA-binding Transcription Transcription regulation | MEEITQHFGV | MEEITQHFGVGASSHGHGHGQHHHHHHHHHPWASSLSAVVAPLPPQPPSAGLPLTLNTVAATGNSGGSGNPVLQLANGGGLLDACVKAKEPSSSSPYAGDVEAIKAKIISHPHYYSLLTAYLECNKVGAPPEVSARLTEIAQEVEARQRTALGGLAAATEPELDQFMEAYHEMLVKFREELTRPLQEAMEFMRRVESQLNSLSISGRSLRNILSSGSSEEDQEGSGGETELPEVDAHGVDQELKHHLLKKYSGYLSSLKQELSKKKKKGKLPKEARQQLLSWWDQHYKWPYPSETQKVALAESTGLDLKQINNWFINQRK... | anther dehiscence negative regulation of auxin mediated signaling pathway negative regulation of DNA-templated transcription plasmodesmata-mediated intercellular transport cytoplasm; microtubule cytoskeleton; nucleus; plasmodesma DNA-binding transcription factor activity, RNA polymerase II-specific protein homodimeriza... |
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors | canonical inflammasome complex; cell leading edge; cytoplasm; cytoplasmic stress granule; lamellipodium; nucleus; plasma membrane | ATP binding ATP hydrolysis activity RNA binding RNA helicase activity | Xenopus laevis | ATP-binding Cell membrane Cell projection Cytoplasm Helicase Hydrolase Inflammasome Membrane Nucleotide-binding Nucleus Reference proteome RNA-binding | MSHVAVENVL | MSHVAVENVLNLDQQFAGLDLNSADAESGVAGTKGRYIPPHLRNKEASRNDSNWDSGRGGNGYINGMQDDRDGRMNGYDRGGYGSRGTGRSDRGFYDRENSGWNSGRDKDAYSSFGSRGDRGKGSLFNERGSGSRRTDDRRQDGFDGMGNRSDKSGFGRFDRGNSRWSDDRNDEDDWSKPLAPNDRVEQELFSGSNTGINFEKYDDIPVEATGSNCPPHIESFHDVTMGEIIMGNIQLTRYTRPTPVQKHAIPIIIEKRDLMACAQTGSGKTAAFLLPILSQIYADGPGDAMKHLQENGRYGRRKQFPLSLVLAPTRELA... | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors canonical inflammasome complex; cell leading edge; cytoplasm; cytoplasmic stress granule; lamellipodium; nucleus; plasma membrane ATP binding ATP hydrolysis activity RNA binding RNA helicase activity Xenopus laevis ATP-binding Cell ... |
basement membrane organization collagen catabolic process collagen fibril organization extracellular matrix disassembly extracellular matrix organization negative regulation of fat cell differentiation proteolysis | extracellular matrix; extracellular region; extracellular space; Golgi lumen | metalloendopeptidase activity serine-type endopeptidase activity zinc ion binding | Homo sapiens | Calcium Cleavage on pair of basic residues Collagen degradation Direct protein sequencing Disulfide bond Extracellular matrix Hydrolase Metal-binding Metalloprotease Protease Reference proteome Repeat Secreted Signal Zinc Zymogen | MAPAAWLRSA | MAPAAWLRSAAARALLPPMLLLLLQPPPLLARALPPDAHHLHAERRGPQPWHAALPSSPAPAPATQEAPRPASSLRPPRCGVPDPSDGLSARNRQKRFVLSGGRWEKTDLTYRILRFPWQLVQEQVRQTMAEALKVWSDVTPLTFTEVHEGRADIMIDFARYWHGDDLPFDGPGGILAHAFFPKTHREGDVHFDYDETWTIGDDQGTDLLQVAAHEFGHVLGLQHTTAAKALMSAFYTFRYPLSLSPDDCRGVQHLYGQPWPTVTSRTPALGPQAGIDTNEIAPLEPDAPPDACEASFDAVSTIRGELFFFKAGFVWRLR... | basement membrane organization collagen catabolic process collagen fibril organization extracellular matrix disassembly extracellular matrix organization negative regulation of fat cell differentiation proteolysis extracellular matrix; extracellular region; extracellular space; Golgi lumen metalloendopeptidase activity... |
axon guidance chemosensory jump behavior dendrite guidance dendrite morphogenesis detection of chemical stimulus involved in sensory perception of smell positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II synaptic target recognition | nucleus | DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding transcription corepressor activity | Drosophila melanogaster | Activator Alternative splicing DNA-binding Homeobox Nucleus Olfaction Reference proteome Repressor Sensory transduction Transcription Transcription regulation | MTMSMYSTTD | MTMSMYSTTDKMKMSAPSCFPGRYSPSYRSSEQMRRCMPNPSIHISSSCDSLESRLLEDASLLCNSWSARQNGDIFAGINDGILSRAEALAAVDIQKHQAQHVHSQMPSQIKHDVMYHHHSMSGPPQRPLQENPFSRQMHHSMDQLDMLDPTGSMTTLAPISESPLTPTHQHLHGSYHSMNHMMSHHHPGTLSGHTGGHHGHSAVHHPVITAAVAAAGLHPDTDTDPRELEAFAERFKQRRIKLGVTQADVGKALANLKLPGVGALSQSTICRFESLTLSHNNMIALKPILQAWLEEAEAQAKNKRRDPDAPSVLPAGEK... | axon guidance chemosensory jump behavior dendrite guidance dendrite morphogenesis detection of chemical stimulus involved in sensory perception of smell positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II synaptic target recognition nucleus DNA-binding transcriptio... |
negative regulation of interleukin-1 production perturbation by virus of host apoptosis regulation of apoptotic process suppression by virus of host apoptotic process | host cell mitochondrial outer membrane; host cell mitochondrion; membrane; mitochondrion | protein sequestering activity | Vaccinia virus ) | Early protein Host cytoplasm Host membrane Host mitochondrion Host mitochondrion outer membrane Host-virus interaction Inhibition of host apoptosis by viral BCL2-like protein Membrane Modulation of host cell apoptosis by virus Reference proteome | MLSMFMCNNI | MLSMFMCNNIVDYVDDIDNGIVQDIEDEASNNVDHDYVYPLPENMVYRFDKSTNILDYLSTERDHVMMAVRYYMSKQRLDDLYRQLPTKTRSYIDIINIYCDKVSNDYNRDMNIMYDMASTKSFTVYDINNEVNTILMDNKGLGVRLATISFITELGRRCMNPVETIKMFTLLSHTICDDYFVDYITDISPPDNTIPNTSTREYLKLIGITAIMFATYKTLKYMIG | negative regulation of interleukin-1 production perturbation by virus of host apoptosis regulation of apoptotic process suppression by virus of host apoptotic process host cell mitochondrial outer membrane; host cell mitochondrion; membrane; mitochondrion protein sequestering activity Vaccinia virus )Early protein Ho... |
bone development chaperone-mediated protein folding neutrophil chemotaxis nuclear transport positive regulation by host of viral genome replication positive regulation by host of viral process positive regulation of multicellular organism growth protein folding protein peptidyl-prolyl isomerization protein stabilizatio... | cytoplasm; endoplasmic reticulum chaperone complex; endoplasmic reticulum lumen; intracellular membrane-bounded organelle; melanosome; nucleoplasm; perinuclear region of cytoplasm; protein-containing complex; smooth endoplasmic reticulum | cyclosporin A binding peptidyl-prolyl cis-trans isomerase activity RNA polymerase binding | Rattus norvegicus | Acetylation Endoplasmic reticulum Isomerase Reference proteome Rotamase S-nitrosylation Signal | MLRLSERNMK | MLRLSERNMKVLFAAALIVGSVVFLLLPGPSVANDKKKGPKVTVKVYFDFQIGDEPVGRVTFGLFGKTVPKTVDNFVALATGEKGFGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTVKTSWLDGKHVVFGKVLEGMDVVRKVENTKTDSRDKPLKDVIIVDCGKIEVEKPFAIAKE | bone development chaperone-mediated protein folding neutrophil chemotaxis nuclear transport positive regulation by host of viral genome replication positive regulation by host of viral process positive regulation of multicellular organism growth protein folding protein peptidyl-prolyl isomerization protein stabilizatio... |
bone development chaperone-mediated protein folding neutrophil chemotaxis positive regulation by host of viral genome replication positive regulation by host of viral process positive regulation of multicellular organism growth protein folding protein peptidyl-prolyl isomerization protein stabilization | cytoplasm; endoplasmic reticulum; endoplasmic reticulum chaperone complex; endoplasmic reticulum lumen; intracellular membrane-bounded organelle; melanosome; nucleoplasm; perinuclear region of cytoplasm; protein-containing complex; smooth endoplasmic reticulum | cyclosporin A binding peptidyl-prolyl cis-trans isomerase activity RNA polymerase binding | Mus musculus | Acetylation Endoplasmic reticulum Isomerase Reference proteome Rotamase Signal | MLRLSERNMK | MLRLSERNMKVLFAAALIVGSVVFLLLPGPSVANDKKKGPKVTVKVYFDLQIGDESVGRVVFGLFGKTVPKTVDNFVALATGEKGFGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTVKTSWLDGKHVVFGKVLEGMDVVRKVESTKTDSRDKPLKDVIIVDSGKIEVEKPFAIAKE | bone development chaperone-mediated protein folding neutrophil chemotaxis positive regulation by host of viral genome replication positive regulation by host of viral process positive regulation of multicellular organism growth protein folding protein peptidyl-prolyl isomerization protein stabilization cytoplasm; endop... |
cell division DNA damage response endoplasmic reticulum unfolded protein response fat cell differentiation G1/S transition of mitotic cell cycle lactation liver regeneration mammary gland alveolus development mammary gland epithelial cell proliferation mitotic cell cycle phase transition mitotic G1 DNA damage checkpoin... | bicellular tight junction; cyclin D1-CDK4 complex; cyclin-dependent protein kinase holoenzyme complex; cytoplasm; cytosol; nuclear membrane; nucleoplasm; nucleus; transcription repressor complex | cyclin-dependent protein serine/threonine kinase activator activity cyclin-dependent protein serine/threonine kinase regulator activity enzyme binding histone deacetylase binding proline-rich region binding protein kinase activity protein kinase binding transcription corepressor activity | Homo sapiens | 3D-structure Cell cycle Cell division Chromosomal rearrangement Cyclin Cytoplasm DNA damage Isopeptide bond Membrane Nucleus Phosphoprotein Proto-oncogene Reference proteome Repressor Transcription Transcription regulation Ubl conjugation | MEHQLLCCEV | MEHQLLCCEVETIRRAYPDANLLNDRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKCDPDCLRACQEQIEALLESSLRQAQQNMDPKAAEEEEEEEEEVDLACTPTDVRDVDI | cell division DNA damage response endoplasmic reticulum unfolded protein response fat cell differentiation G1/S transition of mitotic cell cycle lactation liver regeneration mammary gland alveolus development mammary gland epithelial cell proliferation mitotic cell cycle phase transition mitotic G1 DNA damage checkpoin... |
intracellular protein transport protein geranylgeranylation protein targeting to membrane small GTPase mediated signal transduction vesicle-mediated transport visual perception | cytoplasm; cytosol; nucleus; Rab-protein geranylgeranyltransferase complex | GDP-dissociation inhibitor activity GTPase activator activity Rab geranylgeranyltransferase activity small GTPase binding | Homo sapiens | Alternative splicing Cytoplasm Disease variant GTPase activation Reference proteome Sensory transduction Vision | MADTLPSEFD | MADTLPSEFDVIVIGTGLPESIIAAACSRSGRRVLHVDSRSYYGGNWASFSFSGLLSWLKEYQENSDIVSDSPVWQDQILENEEAIALSRKDKTIQHVEVFCYASQDLHEDVEEAGALQKNHALVTSANSTEAADSAFLPTEDESLSTMSCEMLTEQTPSSDPENALEVNGAEVTGEKENHCDDKTCVPSTSAEDMSENVPIAEDTTEQPKKNRITYSQIIKEGRRFNIDLVSKLLYSRGLLIDLLIKSNVSRYAEFKNITRILAFREGRVEQVPCSRADVFNSKQLTMVEKRMLMKFLTFCMEYEKYPDEYKGYEEITF... | intracellular protein transport protein geranylgeranylation protein targeting to membrane small GTPase mediated signal transduction vesicle-mediated transport visual perception cytoplasm; cytosol; nucleus; Rab-protein geranylgeranyltransferase complex GDP-dissociation inhibitor activity GTPase activator activity Rab ge... |
behavioral response to ethanol cellular response to calcium ion cellular response to cAMP cellular response to cocaine cellular response to estradiol stimulus cellular response to estrogen stimulus cellular response to gonadotropin-releasing hormone cellular response to potassium ion cellular response to tumor necrosis... | axon terminus; dendrite; dense core granule; extracellular region; extracellular space; microtubule; multivesicular body; nucleus; perikaryon; secondary lysosome; secretory granule; varicosity | corticotropin-releasing hormone binding peptide binding | Homo sapiens | Direct protein sequencing Disulfide bond Glycoprotein Reference proteome Secreted Signal | MSPNFKLQCH | MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRCLDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNLFPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGIGDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQLEPYELENPNGNSIGEFCLS... | behavioral response to ethanol cellular response to calcium ion cellular response to cAMP cellular response to cocaine cellular response to estradiol stimulus cellular response to estrogen stimulus cellular response to gonadotropin-releasing hormone cellular response to potassium ion cellular response to tumor necrosis... |
behavioral response to ethanol cellular response to calcium ion cellular response to cAMP cellular response to cocaine cellular response to estradiol stimulus cellular response to estrogen stimulus cellular response to gonadotropin-releasing hormone cellular response to immobilization stress cellular response to potass... | axon terminus; dendrite; dense core granule; extracellular space; microtubule; multivesicular body; nucleus; perikaryon; secondary lysosome; secretory granule; varicosity | corticotropin-releasing hormone binding peptide binding | Rattus norvegicus | Disulfide bond Glycoprotein Reference proteome Secreted Signal | MSPNFKLQCH | MSPNFKLQCHFTLILLTALRGESRYLEVQEAAVYDPFLLFSANLKRNLAEEQPYRRALRCLDMLSLPGQFTFTADQPQLHCAAFFIGEPEEFITIHFDLVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLPTRERYTDFCESGLTRRSVTSSQNVAMVFFRVHEPGNGFTITIKTDPNLFPCNIISQTPSGRFALVVPYQHQNCSFSIIYPVTIKISDLALGHLHGLQLKKPAAGCGGTGDFVELLGGTGLDTSKMMLLVDLCYPFHGPAQMKISCDNAVVRMVSSGKHMNRVTFEYRQLEPLELETSTRNSIPEYCLS... | behavioral response to ethanol cellular response to calcium ion cellular response to cAMP cellular response to cocaine cellular response to estradiol stimulus cellular response to estrogen stimulus cellular response to gonadotropin-releasing hormone cellular response to immobilization stress cellular response to potass... |
amino acid metabolic process generation of precursor metabolites and energy hormone biosynthetic process thyroid hormone metabolic process | endoplasmic reticulum membrane | selenium binding thyroxine 5'-deiodinase activity | Rattus norvegicus | Endoplasmic reticulum Membrane Oxidoreductase Reference proteome Selenocysteine Thyroid hormones biosynthesis Transmembrane Transmembrane helix | MGLSQLWLWL | MGLSQLWLWLKRLVIFLQVALEVATGKVLMTLFPERVKQNILAMGQKTGMTRNPRFAPDNWVPTFFSIQYFWFVLKVRWQRLEDRAEYGGLAPNCTVVRLSGQKCNVWDFIQGSRPLVLNFGSCTUPSFLLKFDQFKRLVDDFASTADFLIIYIEEAHATDGWAFKNNVDIRQHRSLQDRLRAAHLLLARSPQCPVVVDTMQNQSSQLYAALPERLYVIQEGRICYKGKPGPWNYNPEEVRAVLEKLCIPPGHMPQF | amino acid metabolic process generation of precursor metabolites and energy hormone biosynthetic process thyroid hormone metabolic process endoplasmic reticulum membrane selenium binding thyroxine 5'-deiodinase activity Rattus norvegicus Endoplasmic reticulum Membrane Oxidoreductase Reference proteome Selenocysteine Th... |
endoplasmic reticulum to Golgi vesicle-mediated transport protein retention in ER lumen protein transport retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum T cell apoptotic process T cell differentiation | cis-Golgi network; COPI-coated vesicle membrane; endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment; endoplasmic reticulum-Golgi intermediate compartment membrane; Golgi membrane; transport vesicle | ER retention sequence binding KDEL sequence binding | Homo sapiens | Alternative splicing Cytoplasmic vesicle Endoplasmic reticulum ER-Golgi transport Golgi apparatus Membrane Phosphoprotein Protein transport Receptor Reference proteome Transmembrane Transmembrane helix Transport | MNLFRFLGDL | MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYNTCMKVVYIACSFTTVWLIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA | endoplasmic reticulum to Golgi vesicle-mediated transport protein retention in ER lumen protein transport retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum T cell apoptotic process T cell differentiation cis-Golgi network; COPI-coated vesicle membrane; endoplasmic reticulum; endoplasmic reticulum me... |
bile acid biosynthetic process cellular response to reactive oxygen species cholesterol homeostasis fatty acid beta-oxidation negative regulation of epithelial cell proliferation negative regulation of fibroblast proliferation nervous system development neuron migration peroxisome organization pexophagy protein destabi... | Cdc73/Paf1 complex; peroxisomal membrane; peroxisome | ubiquitin protein ligase activity zinc ion binding | Rattus norvegicus | Disulfide bond Membrane Metal-binding Peroxisome Peroxisome biogenesis Protein transport Reference proteome Transferase Transmembrane Transmembrane helix Transport Ubl conjugation pathway Zinc Zinc-finger | MAAREESTQS | MAAREESTQSANRVLRISQLDALELNKALEQLVWSQFTQCFHGFKPGLLARFEPEVKAFLWLFLWRFTIYSKNATVGQSVLNIQYKNDSSPNPVYQPPSKNQKLLYAVCTIGGRWLEERCYDLFRNRHLASFGKAKQCMNFVVGLLKLGELMNFLIFLQKGKFATLTERLLGIHSVFCKPQSMREVGFEYMNRELLWHGFAEFLVFLLPLINIQKLKAKLSSWCIPLTSTAGSDSTLGSSGKECALCGEWPTMPHTIGCEHVFCYYCVKSSFLFDMYFTCPKCGTEVHSVQPLKSGIEMSEVNAL | bile acid biosynthetic process cellular response to reactive oxygen species cholesterol homeostasis fatty acid beta-oxidation negative regulation of epithelial cell proliferation negative regulation of fibroblast proliferation nervous system development neuron migration peroxisome organization pexophagy protein destabi... |
cellular response to sodium phosphate mast cell degranulation negative regulation of voltage-gated potassium channel activity negative regulation of voltage-gated sodium channel activity neuropeptide signaling pathway ossification positive regulation of behavioral fear response positive regulation of peptide hormone se... | extracellular region; extracellular space; neuron projection; neuronal dense core vesicle; secretory granule lumen | neuropeptide hormone activity | Rattus norvegicus | Amidation Cell projection Cleavage on pair of basic residues Cytoplasmic vesicle Mast cell degranulation Reference proteome Secreted Signal | MRGSELSLLL | MRGSELSLLLLALVLCQAPRGPAAPVSTGAGGGTVLAKMYPRGSHWAVGHLMGKKSTDELPPLYAADRDGLKEQLRGYIRWEEAARNLLGLLEAAGNRSHQPPQDQPLGSLQPTWDPEDGSYFSDAQNAKLVDSLLQVLKGKEGTAS | cellular response to sodium phosphate mast cell degranulation negative regulation of voltage-gated potassium channel activity negative regulation of voltage-gated sodium channel activity neuropeptide signaling pathway ossification positive regulation of behavioral fear response positive regulation of peptide hormone se... |
cytokine-mediated signaling pathway defense response to protozoan immune response immunoglobulin mediated immune response interleukin-4-mediated signaling pathway negative regulation of T-helper 1 cell differentiation positive regulation of chemokine production positive regulation of cold-induced thermogenesis positive... | centriolar satellite; external side of plasma membrane; extracellular region; nucleoplasm; plasma membrane; receptor complex | cytokine receptor activity interleukin-4 receptor activity | Homo sapiens | 3D-structure Alternative splicing Cell membrane Disulfide bond Glycoprotein Immunity Membrane Phosphoprotein Receptor Reference proteome Secreted Signal Transmembrane Transmembrane helix | MGWLCSGLLF | MGWLCSGLLFPVSCLVLLQVASSGNMKVLQEPTCVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTCIPENNGGAGCVCHLLMDDVVSADNYTLDLWAGQQLLWKGSFKPSEHVKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYLEPSLRIAASTLKSGISYRARVRAWAQCYNTTWSEWSPSTKWHNSYREPFEQHLLLGVSVSCIVILAVCLLCYVSITKIKKEWWDQIPNPARSRLVAIIIQDAQGSQWEKRSRGQEPAKCPHWKNCLTKLLPCFLEHNMKR... | cytokine-mediated signaling pathway defense response to protozoan immune response immunoglobulin mediated immune response interleukin-4-mediated signaling pathway negative regulation of T-helper 1 cell differentiation positive regulation of chemokine production positive regulation of cold-induced thermogenesis positive... |
actin cytoskeleton organization apical junction assembly cell junction assembly cell migration cellular response to chemokine cleavage furrow formation cytoplasmic microtubule organization establishment of epithelial cell apical/basal polarity mitotic cleavage furrow formation positive regulation of canonical NF-kappaB... | apical junction complex; cell cortex; cleavage furrow; cytoplasmic side of plasma membrane; cytoskeleton; cytosol; dendritic spine; lamellipodium; midbody; nucleus; plasma membrane | G protein activity GTP binding GTPase activity protein kinase binding | Canis lupus familiaris | Cell cycle Cell division Cell membrane Cell projection Cytoplasm Cytoskeleton GTP-binding Hydrolase Isopeptide bond Lipoprotein Membrane Methylation Nucleotide-binding Nucleus Phosphoprotein Prenylation Proto-oncogene Reference proteome Ubl conjugation | MAAIRKKLVI | MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPTEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQARRGKKKSGCLVL | actin cytoskeleton organization apical junction assembly cell junction assembly cell migration cellular response to chemokine cleavage furrow formation cytoplasmic microtubule organization establishment of epithelial cell apical/basal polarity mitotic cleavage furrow formation positive regulation of canonical NF-kappaB... |
negative regulation by host of symbiont catalytic activity positive regulation of exocytosis protein transport Rab protein signal transduction regulation of protein localization retrograde transport, endosome to Golgi | cytosol; endoplasmic reticulum membrane; Golgi membrane; late endosome; lysosome; melanosome; phagocytic vesicle; phagocytic vesicle membrane; plasma membrane | GDP binding GTP binding GTPase activity | Canis lupus familiaris | 3D-structure Acetylation Cell membrane Cytoplasmic vesicle Endoplasmic reticulum Endosome Golgi apparatus GTP-binding Lipoprotein Membrane Nucleotide-binding Phosphoprotein Prenylation Protein transport Reference proteome Transport | MAGKSSLFKV | MAGKSSLFKVILLGDGGVGKSSLMNRYVTNKFDTQLFHTIGVEFLNKDLEVDGHFVTMQIWDTAGQERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNKIDISERQVSTEEAQAWCRDNGDYPYFETSAKDATNVAAAFEEAVRRVLATEDRSDHLIQTDTVSLHRKPKPSSSCC | negative regulation by host of symbiont catalytic activity positive regulation of exocytosis protein transport Rab protein signal transduction regulation of protein localization retrograde transport, endosome to Golgi cytosol; endoplasmic reticulum membrane; Golgi membrane; late endosome; lysosome; melanosome; phagocyt... |
axonogenesis cellular response to insulin stimulus endosomal transport establishment of neuroblast polarity Golgi to plasma membrane protein transport Golgi to plasma membrane transport polarized epithelial cell differentiation protein localization to basolateral plasma membrane protein localization to plasma membrane ... | cilium; endoplasmic reticulum membrane; endosome; endosome membrane; Golgi apparatus; Golgi membrane; insulin-responsive compartment; phagocytic vesicle membrane; recycling endosome; recycling endosome membrane; trans-Golgi network | G protein activity GDP binding GTP binding myosin V binding | Canis lupus familiaris | Acetylation Cell projection Cytoplasmic vesicle Endoplasmic reticulum Endosome Golgi apparatus GTP-binding Hydrolase Isopeptide bond Lipoprotein Membrane Nucleotide-binding Phosphoprotein Prenylation Protein transport Reference proteome Transport Ubl conjugation | MAKKTYDLLF | MAKKTYDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDDKRVVPKGKGEQIAREHGIRFFETSAKVNINIEKAFLTLAEDILRKTPVKEPNSENVDISSGGGVTGWKSKCC | axonogenesis cellular response to insulin stimulus endosomal transport establishment of neuroblast polarity Golgi to plasma membrane protein transport Golgi to plasma membrane transport polarized epithelial cell differentiation protein localization to basolateral plasma membrane protein localization to plasma membrane ... |
actin filament severing actin polymerization or depolymerization barbed-end actin filament capping cell projection assembly cellular response to type II interferon central nervous system development | actin cytoskeleton; centriole; cytoplasm; Flemming body; lamellipodium; melanosome; mitotic spindle; nucleolus; nucleoplasm; nucleus; phagocytic vesicle; ruffle | actin filament binding phosphatidylinositol-4,5-bisphosphate binding protein domain specific binding protein-containing complex binding | Mus musculus | Acetylation Actin capping Actin-binding Cell projection Cytoplasm Direct protein sequencing Nucleus Phosphoprotein Reference proteome Repeat | MYTPIPQSGS | MYTPIPQSGSPFPASVQDPGLHIWRVEKLKPVPIARESHGIFFSGDSYLVLHNGPEEASHLHLWIGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYYREGGVESAFHKTTSGARGAAIRKLYQVKGKKNIRATERPLSWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALAIRDSERQGKAQVEIITDGEEPAEMIQVLGPKPALKEGNPEEDITADQTRPNAQAAALYKVSDATGQMNLTKVADSSPFASELLIPDDCFVLDNGLCAQIYIWKGRKANEKERQAALQVADGF... | actin filament severing actin polymerization or depolymerization barbed-end actin filament capping cell projection assembly cellular response to type II interferon central nervous system development actin cytoskeleton; centriole; cytoplasm; Flemming body; lamellipodium; melanosome; mitotic spindle; nucleolus; nucleopla... |
arachidonic acid metabolic process cholesterol metabolic process estrogen metabolic process retinol metabolic process | endoplasmic reticulum membrane | aromatase activity estrogen 16-alpha-hydroxylase activity estrogen 2-hydroxylase activity heme binding hydroperoxy icosatetraenoate dehydratase activity iron ion binding | Mesocricetus auratus | Direct protein sequencing Endoplasmic reticulum Fatty acid metabolism Glycoprotein Heme Iron Lipid metabolism Lyase Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Reference proteome Steroid metabolism Sterol metabolism | MALSQYTSLS | MALSQYTSLSTELVLATAIFCIVFWVARALRTQVPKGLKTPPGPWGLPILGHVLTLGKNPHLSLTKLSKQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYSFTLITNGKSMTFNPDCGPVWAARRRLAQDALKSFSIASDPTSASSCYLEDHVIKEANHLVSKLQKLTAEVGHFEPVNQVVESVANVIGAMCFGKNFPRKSEEMLRIVKGSSDFVENVSSGNAVDFFPILRYLPNPDLKRFKNFNDNFVLFLQKTVQEHYQDFNKNSIQDITGALFKHSENSKDSGGLIPQEKIVNIVNDLFGAGFDTV... | arachidonic acid metabolic process cholesterol metabolic process estrogen metabolic process retinol metabolic process endoplasmic reticulum membrane aromatase activity estrogen 16-alpha-hydroxylase activity estrogen 2-hydroxylase activity heme binding hydroperoxy icosatetraenoate dehydratase activity iron ion binding M... |
arachidonic acid metabolic process xenobiotic metabolic process | cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; mitochondrion | anandamide 11,12 epoxidase activity anandamide 14,15 epoxidase activity anandamide 8,9 epoxidase activity aromatase activity heme binding iron ion binding monooxygenase activity oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin ... | Mus musculus | Endoplasmic reticulum Heme Iron Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Phosphoprotein Reference proteome | MELLTGAGLW | MELLTGAGLWSVAIFTVIFILLVDLMHRHQRWTSRYPPGPVPWPVLGNLLQVDLDNMPYSLYKLQNRYGDVFSLQMGWKPMVVINGLKAMKEVLLTCGEDTADRPQVPIFEYLGVKPGSQGVVLAPYGPEWREQRRFSVSTLRNFGLGKKSLEDWVTKEARHLCDAFTAQAGQPINPNTMLNNAVCNVIASLIFARRFEYEDPYLIRMQKVLEDSLTEISGLIPEVLNMFPILLRIPGLPGKVFQGQKSLLAIVENLLTENRNTWDPDQPPRNLTDAFLAEIEKVKGNAESSFNDENLRMVVLDLFTAGMVTTSTTLSWA... | arachidonic acid metabolic process xenobiotic metabolic process cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; mitochondrion anandamide 11,12 epoxidase activity anandamide 14,15 epoxidase activity anandamide 8,9 epoxidase activity aromatase activity heme binding iron ion binding mo... |
arachidonic acid metabolic process xenobiotic metabolic process | cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; mitochondrion | anandamide 11,12 epoxidase activity anandamide 14,15 epoxidase activity anandamide 8,9 epoxidase activity aromatase activity heme binding iron ion binding monooxygenase activity oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin ... | Mus musculus | Endoplasmic reticulum Heme Iron Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Reference proteome | MELLTGAGLW | MELLTGAGLWSVAIFTVIFILLVDLMHRHQHWTSRCPPGPVPWPVLGNLLQVDLGNMPYSLYKLQNRYGDVFSLQMGWKPMVVINGLKAMKEVLLTCGEDTADRPQVPIFEYLGVKPGSQGVVLAPYGPEWQEQRRFSVSTLRNFGLGKKSLEDWVTKEARHLCDAFTAQAGQSINPNTMLNNAVCNVIASLIFARRFEYEDPYLIRMLKMLKECFTEISGFIPGVLNEFPIFLRIPGLADMVFQGQKSFMAILDNLLTENRTTWDPDQPPRNLTDAFLAEIEKAKGNPESSFNDENLRMVVGDLFTAGMVTTSTTLSWA... | arachidonic acid metabolic process xenobiotic metabolic process cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; mitochondrion anandamide 11,12 epoxidase activity anandamide 14,15 epoxidase activity anandamide 8,9 epoxidase activity aromatase activity heme binding iron ion binding mo... |
estrogen metabolic process lipid hydroxylation oxidative demethylation retinoic acid metabolic process retinol metabolic process steroid biosynthetic process steroid metabolic process xenobiotic metabolic process | endoplasmic reticulum membrane | all-trans retinoic acid 18-hydroxylase activity aromatase activity estrogen 16-alpha-hydroxylase activity estrogen 2-hydroxylase activity heme binding iron ion binding monooxygenase activity oxygen binding retinoic acid 4-hydroxylase activity steroid hydroxylase activity testosterone 6-beta-hydroxylase activity | Homo sapiens | 3D-structure Alternative splicing Direct protein sequencing Endoplasmic reticulum Heme Iron Lipid biosynthesis Lipid metabolism Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Reference proteome Steroid biosynthesis | MDLIPNLAVE | MDLIPNLAVETWLLLAVSLILLYLYGTRTHGLFKKLGIPGPTPLPFLGNALSFRKGYWTFDMECYKKYRKVWGIYDCQQPMLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKNAISIAEDEEWKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVSIDSLNNPQDPFVENTKKLLRFNPLDPFVLSIKVFPFLTPILEALNITVFPRKVISFLTKSVKQIKEGRLKETQKHRVDFLQLMIDSQNSKDSETHKALSDLELMAQSIIFIFAGYETTSSVLSFIIYE... | estrogen metabolic process lipid hydroxylation oxidative demethylation retinoic acid metabolic process retinol metabolic process steroid biosynthetic process steroid metabolic process xenobiotic metabolic process endoplasmic reticulum membrane all-trans retinoic acid 18-hydroxylase activity aromatase activity estrogen ... |
hormone metabolic process organic hydroxy compound metabolic process oxidative demethylation progesterone metabolic process steroid metabolic process | endoplasmic reticulum membrane | aromatase activity heme binding iron ion binding monooxygenase activity steroid hydroxylase activity testosterone 6-beta-hydroxylase activity | Canis lupus familiaris | Endoplasmic reticulum Heme Iron Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Reference proteome | MDLIPSFSTE | MDLIPSFSTETWLLLAISLVLLYLYGTYTHGIFRKLGIPGPTPLPFVGTALGYRNGFYVFDMKCFSKYGRMWGFYDGRQPVLAITDPDMIKTVLVKECYSVFTNRRTLGPVGFMKSAISLSEDEEWKRMRTLLSPTFTTGKLKEMFPIIGQYGDVLVNNLRKEAEKGKAINLKDVFGAYSMDVITSTSFGVNIDSLNHPQDPFVENTKKLLKFDFLDPFFFSILLFPFLTPVFEILNIWLFPKKVTDFFRKSVERMKESRLKDKQKHRVDFLQLMINSQNSKEMDTHKALSDLELVAQSIIFIFAGYETTSTSLSFLMYE... | hormone metabolic process organic hydroxy compound metabolic process oxidative demethylation progesterone metabolic process steroid metabolic process endoplasmic reticulum membrane aromatase activity heme binding iron ion binding monooxygenase activity steroid hydroxylase activity testosterone 6-beta-hydroxylase activi... |
arachidonic acid metabolic process fatty acid metabolic process icosanoid biosynthetic process kidney development lauric acid metabolic process linoleic acid metabolic process response to testosterone | endoplasmic reticulum membrane; intracellular membrane-bounded organelle | alkane 1-monooxygenase activity arachidonic acid monooxygenase activity aromatase activity fatty acid omega-hydroxylase activity heme binding iron ion binding monooxygenase activity | Rattus norvegicus | Endoplasmic reticulum Heme Iron Lipid metabolism Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Phosphoprotein Reference proteome Transmembrane Transmembrane helix | MSGSALSFTI | MSGSALSFTIFPGSILGFLQIATVLTVLLLLFKTAQFYLHRRWLLRATQQFPSPPSHWFFGHKIPKDQEFQDILTRVKNFPSACPQWLWGSNVRIQVYDPDYMKLILGRSDPKSHHSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDTLKPYVGIMADSVRIMLDKWEQIVGQDSTLEIFQHITLMTLDTIMKCAFSQEGSVQLDRKYKSYIKAVEDLNNLSFFRIRNIFHQNDIIYSLSSNGRKARSAWQLAHEHTDQVIKSRKAQLQDEEELQKVKQKRRLDFLDILLFARIENGSSLSDKDLRAEVDTFMFEG... | arachidonic acid metabolic process fatty acid metabolic process icosanoid biosynthetic process kidney development lauric acid metabolic process linoleic acid metabolic process response to testosterone endoplasmic reticulum membrane; intracellular membrane-bounded organelle alkane 1-monooxygenase activity arachidonic ac... |
anatomical structure development anterior/posterior pattern specification blood vessel morphogenesis cell differentiation female gonad development fertilization forebrain development interneuron migration lymphatic endothelial cell fate commitment maternal placenta development negative regulation of cyclin-dependent pr... | cytosol; nucleoplasm; nucleus | DNA-binding transcription factor activity nuclear receptor activity protein homodimerization activity retinoic acid binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding zinc ion binding | Homo sapiens | 3D-structure Activator Alternative splicing Disease variant DNA-binding Metal-binding Nucleus Phosphoprotein Receptor Reference proteome Transcription Transcription regulation Zinc Zinc-finger | MAMVVSTWRD | MAMVVSTWRDPQDEVPGSQGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAGGQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVL... | anatomical structure development anterior/posterior pattern specification blood vessel morphogenesis cell differentiation female gonad development fertilization forebrain development interneuron migration lymphatic endothelial cell fate commitment maternal placenta development negative regulation of cyclin-dependent pr... |
arachidonic acid metabolic process epoxygenase P450 pathway icosanoid biosynthetic process response to testosterone xenobiotic metabolic process | cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle | arachidonic acid 11,12-epoxygenase activity arachidonic acid 14,15-epoxygenase activity arachidonic acid epoxygenase activity heme binding iron ion binding monooxygenase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one ... | Rattus norvegicus | Acetylation Endoplasmic reticulum Fatty acid metabolism Heme Iron Lipid metabolism Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Phosphoprotein Reference proteome | MELLGFTTLA | MELLGFTTLALVVSVTCLSLLSVWTKLRTRGRLPPGPTPLPIIGNLLQLNLKDIPASLSKLAKEYGPVYTLYFGTSPTVVLHGYDVVKEALLQQGDEFLGRGPLPIIEDTHKGYGLIFSNGERWKVMRRFSLMTLRNFGMGKRSLEERVQEEARCLVEELQKTKAQPFDPTFILACAPCNVICSILFNDRFQYNDKTFLNLMDLLNKNFQQVNSVWCQMYNLWPTIIKYLPGKHIEFAKRIDDVKNFILEKVKEHQKSLDPANPRDYIDCFLSKIEEEKDNLKSEFHLENLAVCGSNLFTAGTETTSTTLRFGLLLLMKY... | arachidonic acid metabolic process epoxygenase P450 pathway icosanoid biosynthetic process response to testosterone xenobiotic metabolic process cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle arachidonic acid 11,12-epoxygenase activity arachidonic acid 14,15-epoxygenase activity ara... |
glutathione metabolic process xenobiotic metabolic process | cytoplasm | glutathione transferase activity organic cyclic compound binding toxic substance binding | Mus musculus | 3D-structure Acetylation Cytoplasm Direct protein sequencing Reference proteome Transferase | MAAKPKLYYF | MAAKPKLYYFNGRGRMESIRWLLAAAGVEFEEEFLETREQYEKMQKDGHLLFGQVPLVEIDGMMLTQTRAILSYLAAKYNLYGKDLKERVRIDMYADGTQDLMMMIAVAPFKTPKEKEESYDLILSRAKTRYFPVFEKILKDHGEAFLVGNQLSWADIQLLEAILMVEELSAPVLSDFPLLQAFKTRISNIPTIKKFLQPGSQRKPPPDGPYVEVVRTVLKF | glutathione metabolic process xenobiotic metabolic process cytoplasm glutathione transferase activity organic cyclic compound binding toxic substance binding Mus musculus 3D-structure Acetylation Cytoplasm Direct protein sequencing Reference proteome Transferase MAAKPKLYYF MAAKPKLYYFNGRGRMESIRWLLAAAGVEFEEEFLETREQYEKMQK... |
epithelial cell differentiation glutathione metabolic process | mitochondrial matrix; mitochondrion; peroxisome | glutathione peroxidase activity glutathione transferase activity | Rattus norvegicus | 3D-structure Acetylation Direct protein sequencing Mitochondrion Reference proteome Transferase | MGPAPRVLEL | MGPAPRVLELFYDVLSPYSWLGFEVLCRYQHLWNIKLKLRPALLAGIMKDSGNQPPAMVPHKGQYILKEIPLLKQLFQVPMSVPKDFFGEHVKKGTVNAMRFLTAVSMEQPEMLEKVSRELWMRIWSRDEDITESQNILSAAEKAGMATAQAQHLLNKISTELVKSKLRETTGAACKYGAFGLPTTVAHVDGKTYMLFGSDRMELLAYLLGEKWMGPVPPTLNARL | epithelial cell differentiation glutathione metabolic process mitochondrial matrix; mitochondrion; peroxisome glutathione peroxidase activity glutathione transferase activity Rattus norvegicus 3D-structure Acetylation Direct protein sequencing Mitochondrion Reference proteome Transferase MGPAPRVLEL MGPAPRVLELFYDVLSPYSW... |
cinnamic acid biosynthetic process L-phenylalanine catabolic process | cytoplasm; protein-containing complex | amino acid binding phenylalanine ammonia-lyase activity | Petroselinum crispum | 3D-structure Cytoplasm Lyase Phenylalanine catabolism Phenylpropanoid metabolism | MENGNGATTN | MENGNGATTNGHVNGNGMDFCMKTEDPLYWGIAAEAMTGSHLDEVKKMVAEYRKPVVKLGGETLTISQVAAISARDGSGVTVELSEAARAGVKASSDWVMDSMNKGTDSYGVTTGFGATSHRRTKQGGALQKELIRFLNAGIFGNGSDNTLPHSATRAAMLVRINTLLQGYSGIRFEILEAITKFLNQNITPCLPLRGTITASGDLVPLSYIAGLLTGRPNSKAVGPTGVILSPEEAFKLAGVEGGFFELQPKEGLALVNGTAVGSGMASMVLFEANILAVLAEVMSAIFAEVMQGKPEFTDHLTHKLKHHPGQIEAAAI... | cinnamic acid biosynthetic process L-phenylalanine catabolic process cytoplasm; protein-containing complex amino acid binding phenylalanine ammonia-lyase activity Petroselinum crispum 3D-structure Cytoplasm Lyase Phenylalanine catabolism Phenylpropanoid metabolism MENGNGATTN MENGNGATTNGHVNGNGMDFCMKTEDPLYWGIAAEAMTGSHLD... |
cell cycle DNA-templated DNA replication DNA-templated DNA replication maintenance of fidelity error-prone translesion synthesis | cytoplasm; epsilon DNA polymerase complex; nuclear replication fork; nucleus | DNA binding | Saccharomyces cerevisiae | 3D-structure Cell cycle Cytoplasm Direct protein sequencing DNA replication DNA-binding Nucleus Phosphoprotein Reference proteome | MFGSGNVLPV | MFGSGNVLPVKIQPPLLRPLAYRVLSRKYGLSIKSDGLSALAEFVGTNIGANWRQGPATIKFLEQFAAVWKQQERGLFIDQSGVKEVIQEMKEREKVEWSHEHPIQHEENILGRTDDDENNSDDEMPIAADSSLQNVSLSSPMRQPTERDEYKQPFKPESSKALDWRDYFKVINASQQQRFSYNPHKMQFIFVPNKKQNGLGGIAGFLPDIEDKVQMFLTRYYLTNDRVMRNENFQNSDMFNPLSSMVSLQNELSNTNRQQQSSSMSITPIKNLLGRDAQNFLLLGLLNKNFKGNWSLEDPSGSVEIDISQTIPTQGHYY... | cell cycle DNA-templated DNA replication DNA-templated DNA replication maintenance of fidelity error-prone translesion synthesis cytoplasm; epsilon DNA polymerase complex; nuclear replication fork; nucleus DNA binding Saccharomyces cerevisiae 3D-structure Cell cycle Cytoplasm Direct protein sequencing DNA replication ... |
adrenal gland development cellular response to cAMP cellular response to epinephrine stimulus cellular response to forskolin cellular response to leptin stimulus cellular response to organic cyclic compound cholesterol metabolic process electron transport chain hormone biosynthetic process NADPH oxidation P450-containi... | mitochondrial crista; mitochondrial matrix; mitochondrion | 2 iron, 2 sulfur cluster binding electron transfer activity enzyme binding iron ion binding | Rattus norvegicus | 2Fe-2S Acetylation Cholesterol metabolism Electron transport Iron Iron-sulfur Lipid metabolism Metal-binding Mitochondrion Phosphoprotein Reference proteome Steroid metabolism Steroidogenesis Sterol metabolism Transit peptide Transport | MAAAPGARLL | MAAAPGARLLRAACASVAFRGLDCRRLLVCGTRAGPAVPQWTPSPHTLAEAGPGRPLSVSARARSSSEDKVTVHFKNRDGETLTTKGKVGDSLLDVVIENNLDIDGFGACEGTLACSTCHLIFEDHIYEKLDAITDEENDMLDLAFGLTNRSRLGCQVCLTKAMDNMTVRVPEAVADVRQSVDMSKNS | adrenal gland development cellular response to cAMP cellular response to epinephrine stimulus cellular response to forskolin cellular response to leptin stimulus cellular response to organic cyclic compound cholesterol metabolic process electron transport chain hormone biosynthetic process NADPH oxidation P450-containi... |
positive regulation of transcription by RNA polymerase II regulation of aerobic respiration regulation of carbohydrate metabolic process | CCAAT-binding factor complex; heterochromatin; nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific promoter-enhancer loop anchoring activity RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding sequence-specific DNA binding | Schizosaccharomyces pombe | Activator DNA-binding Nucleus Reference proteome Transcription Transcription regulation | MNPYEPVEGL | MNPYEPVEGLYVNAKQYHRILKRREARAKLEERLRGVQTTKKPYLHESRHKHAMRRPRGPGGRFLTADKVSKLRAQEAAEAAANGGSTGDDVNATNANDATVPATVSSEVTHTSEGYADSNDSRPSSISNSSESPAPINSATASMSPANNTSGNNITSPNVRGELDMSGNIAMSGGPTNTASTSGPVPHDMTVLPQTDSNTSNLMSSGSQLGSFATASTNGNNSTTTTTSSAAHPGSFHKGTNDYSSTLAGNEHSAFPGLDVYHDDSVSAGAAFIPHNPMDSIDHLDVNDPTATGLPVLPASDIDPLNLTGNTQDSMIIG... | positive regulation of transcription by RNA polymerase II regulation of aerobic respiration regulation of carbohydrate metabolic process CCAAT-binding factor complex; heterochromatin; nucleus DNA-binding transcription activator activity, RNA polymerase II-specific promoter-enhancer loop anchoring activity RNA polymeras... |
NAD biosynthetic process phosphorylation | cytoplasm; plasma membrane | ATP binding DNA binding nicotinamide-nucleotide adenylyltransferase activity ribosylnicotinamide kinase activity | Salmonella typhimurium | ATP-binding Cell membrane Cytoplasm DNA-binding Kinase Membrane Multifunctional enzyme NAD Nucleotide-binding Pyridine nucleotide biosynthesis Reference proteome Repressor Transcription Transcription regulation Transferase | MSSFDYLKTA | MSSFDYLKTAIKQQGCTLQQVADASGMTKGYLSQLLNAKIKSPSAQKLEALHRFLGLEFPRRQKNIGVVFGKFYPLHTGHIYLIQRACSQVDELHIIMGYDDTRDRGLFEDSAMSQQPTVSDRLRWLLQTFKYQKNIRIHAFNEEGMEPYPHGWDVWSNGIKAFMAEKGIQPSWIYTSEEADAPQYLEHLGIETVLVDPERTFMNISGAQIRENPFRYWEYIPTEVKPFFVRTVAILGGESSGKSTLVNKLANIFNTTSAWEYGRDYVFSHLGGDEMALQYSDYDKIALGHAQYIDFAVKYANKVAFIDTDFVTTQAFCK... | NAD biosynthetic process phosphorylation cytoplasm; plasma membrane ATP binding DNA binding nicotinamide-nucleotide adenylyltransferase activity ribosylnicotinamide kinase activity Salmonella typhimurium ATP-binding Cell membrane Cytoplasm DNA-binding Kinase Membrane Multifunctional enzyme NAD Nucleotide-binding Pyridi... |
apoptotic process cellular response to ionizing radiation cellular response to mechanical stimulus centrosome cycle DNA repair negative regulation of angiogenesis negative regulation of blood vessel endothelial cell migration negative regulation of peptidyl-serine phosphorylation of STAT protein negative regulation of ... | cytoplasm; nuclear speck; nucleoplasm; nucleus | kinase binding promoter-specific chromatin binding protein heterodimerization activity protein homodimerization activity | Homo sapiens | 3D-structure Alternative splicing Cell cycle DNA damage Growth arrest Nucleus Phosphoprotein Reference proteome | MTLEEFSAGE | MTLEEFSAGEQKTERMDKVGDALEEVLSKALSQRTITVGVYEAAKLLNVDPDNVVLCLLAADEDDDRDVALQIHFTLIQAFCCENDINILRVSNPGRLAELLLLETDAGPAASEGAEQPPDLHCVLVTNPHSSQWKDPALSQLICFCRESRYMDQWVPVINLPER | apoptotic process cellular response to ionizing radiation cellular response to mechanical stimulus centrosome cycle DNA repair negative regulation of angiogenesis negative regulation of blood vessel endothelial cell migration negative regulation of peptidyl-serine phosphorylation of STAT protein negative regulation of ... |
cellular response to amino acid stimulus cellular response to ethanol cellular response to zinc ion chloride transmembrane transport presynaptic modulation of chemical synaptic transmission protein homooligomerization response to amino acid | dendrite; GABA-ergic synapse; glutamatergic synapse; glycine-gated chloride channel complex; glycinergic synapse; neuron projection; perikaryon; plasma membrane; postsynaptic specialization membrane; presynaptic membrane; synapse | extracellularly glycine-gated chloride channel activity glycine binding glycine-gated chloride ion channel activity metal ion binding transmembrane signaling receptor activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | Rattus norvegicus | Cell membrane Cell projection Chloride Chloride channel Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Metal-binding Phosphoprotein Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport Zinc | MAHVRHFRTL | MAHVRHFRTLLSGFYFWEAALLLSLVATKETNSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWM... | cellular response to amino acid stimulus cellular response to ethanol cellular response to zinc ion chloride transmembrane transport presynaptic modulation of chemical synaptic transmission protein homooligomerization response to amino acid dendrite; GABA-ergic synapse; glutamatergic synapse; glycine-gated chloride cha... |
leukotriene biosynthetic process leukotriene metabolic process peptide catabolic process protein metabolic process proteolysis response to peptide hormone response to zinc ion type I pneumocyte differentiation | cytosol; nucleoplasm; nucleus | aminopeptidase activity epoxide hydrolase activity leukotriene-A4 hydrolase activity metalloaminopeptidase activity tripeptide aminopeptidase activity zinc ion binding | Mus musculus | Acetylation Cytoplasm Hydrolase Leukotriene biosynthesis Metal-binding Metalloprotease Phosphoprotein Protease Reference proteome Zinc | MPEVADTCSL | MPEVADTCSLASPASVCRTQHLHLRCSVDFARRTLTGTAALTVQSQEENLRSLTLDTKDLTIEKVVINGQEVKYTLGESQGYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKQHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGEAPDPEDPSRKIYRFNQRVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSANEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEG... | leukotriene biosynthetic process leukotriene metabolic process peptide catabolic process protein metabolic process proteolysis response to peptide hormone response to zinc ion type I pneumocyte differentiation cytosol; nucleoplasm; nucleus aminopeptidase activity epoxide hydrolase activity leukotriene-A4 hydrolase acti... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.