Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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cellular response to ionizing radiation cellular response to organic cyclic compound cellular response to oxidative stress DNA damage response DNA dealkylation involved in DNA repair DNA repair mammary gland epithelial cell differentiation methylation negative regulation of apoptotic process positive regulation of DNA ... | nucleus | calcium ion binding DNA binding methylated-DNA--cysteine S-methyltransferase activity methyltransferase activity | Rattus norvegicus | Direct protein sequencing DNA damage DNA repair DNA-binding Metal-binding Methyltransferase Nucleus Phosphoprotein Reference proteome Transferase Zinc | MAEICKMKYT | MAEICKMKYTVLDSPLGKIELSGCERGLHGIRFLSGKTPNTDPTEAPACPEVLGGPEGVPEPLVQCTAWLEAYFHEPAATEGLPLPALHHPVFQQDSFTRQVLWKLLKVVKFGEMVSYQQLAALAGNPKAARAVGGAMRSNPVPILIPCHRVIRSDGAIGNYSGGGQTVKEWLLAHEGIPTGQPASKGLGLIGSWLKPSFESSSPKPSG | cellular response to ionizing radiation cellular response to organic cyclic compound cellular response to oxidative stress DNA damage response DNA dealkylation involved in DNA repair DNA repair mammary gland epithelial cell differentiation methylation negative regulation of apoptotic process positive regulation of DNA ... |
translational elongation | cytoplasm; cytosol; eukaryotic translation elongation factor 1 complex | guanyl-nucleotide exchange factor activity translation elongation factor activity | Homo sapiens | 3D-structure Acetylation Direct protein sequencing Elongation factor Isopeptide bond Phosphoprotein Protein biosynthesis Reference proteome Ubl conjugation | MGFGDLKSPA | MGFGDLKSPAGLQVLNDYLADKSYIEGYVPSQADVAVFEAVSSPPPADLCHALRWYNHIKSYEKEKASLPGVKKALGKYGPADVEDTTGSGATDSKDDDDIDLFGSDDEEESEEAKRLREERLAQYESKKAKKPALVAKSSILLDVKPWDDETDMAKLEECVRSIQADGLVWGSSKLVPVGYGIKKLQIQCVVEDDKVGTDMLEEQITAFEDYVQSMDVAAFNKI | translational elongation cytoplasm; cytosol; eukaryotic translation elongation factor 1 complex guanyl-nucleotide exchange factor activity translation elongation factor activity Homo sapiens 3D-structure Acetylation Direct protein sequencing Elongation factor Isopeptide bond Phosphoprotein Protein biosynthesis Referenc... |
proton motive force-driven ATP synthesis proton motive force-driven mitochondrial ATP synthesis substantia nigra development | membrane; mitochondrial inner membrane; mitochondrial matrix; mitochondrial proton-transporting ATP synthase complex; mitochondrial proton-transporting ATP synthase complex, coupling factor F(o); mitochondrion; nucleus | proton transmembrane transporter activity | Homo sapiens | 3D-structure Acetylation CF(0) Hydrogen ion transport Ion transport Membrane Mitochondrion Mitochondrion inner membrane Reference proteome Transit peptide Transport | MLSRVVLSAA | MLSRVVLSAAATAAPSLKNAAFLGPGVLQATRTFHTGQPHLVPVPPLPEYGGKVRYGLIPEEFFQFLYPKTGVTGPYVLGTGLILYALSKEIYVISAETFTALSVLGVMVYGIKKYGPFVADFADKLNEQKLAQLEEAKQASIQHIQNAIDTEKSQQALVQKRHYLFDVQRNNIAMALEVTYRERLYRVYKEVKNRLDYHISVQNMMRRKEQEHMINWVEKHVVQSISTQQEKETIAKCIADLKLLAKKAQAQPVM | proton motive force-driven ATP synthesis proton motive force-driven mitochondrial ATP synthesis substantia nigra development membrane; mitochondrial inner membrane; mitochondrial matrix; mitochondrial proton-transporting ATP synthase complex; mitochondrial proton-transporting ATP synthase complex, coupling factor F(o);... |
de novo' XMP biosynthetic process cellular response to interleukin-4 circadian rhythm GMP biosynthetic process GMP salvage GTP biosynthetic process lymphocyte proliferation purine nucleotide biosynthetic process | cytoplasm; cytosol; nucleus | DNA binding identical protein binding IMP dehydrogenase activity metal ion binding nucleotide binding RNA binding | Mus musculus | Acetylation CBS domain Cytoplasm Direct protein sequencing DNA-binding GMP biosynthesis Isopeptide bond Metal-binding NAD Nucleus Oxidoreductase Phosphoprotein Potassium Purine biosynthesis Reference proteome Repeat RNA-binding Ubl conjugation | MADYLISGGT | MADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMTKREDLVVAPAGVTLKEANEILQRSKKGKLPIVNENDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLALAGVDVVVLDSSQGNSIFQINMIKYIKEKYPSLQVIGGNVVTAAQAKNLIDAGVDA... | de novo' XMP biosynthetic process cellular response to interleukin-4 circadian rhythm GMP biosynthetic process GMP salvage GTP biosynthetic process lymphocyte proliferation purine nucleotide biosynthetic process cytoplasm; cytosol; nucleus DNA binding identical protein binding IMP dehydrogenase activity metal ion bindi... |
9-cis-retinoic acid biosynthetic process 9-cis-retinoic acid metabolic process apoptotic process cellular detoxification of aldehyde embryonic eye morphogenesis fructosamine catabolic process fructose catabolic process gamma-aminobutyric acid biosynthetic process maintenance of lens transparency negative regulation of ... | axon; cytosol; synapse | 3-chloroallyl aldehyde dehydrogenase activity 3-deoxyglucosone dehydrogenase activity aldehyde dehydrogenase (NAD+) activity aminobutyraldehyde dehydrogenase activity benzaldehyde dehydrogenase (NAD+) activity glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity identical protein binding NAD b... | Mus musculus | 3D-structure Acetylation Cell projection Cytoplasm Direct protein sequencing Lipid metabolism NAD Oxidoreductase Phosphoprotein Reference proteome | MSSPAQPAVP | MSSPAQPAVPAPLADLKIQHTKIFINNEWHNSVSGKKFPVLNPATEEVICHVEEGDKADVDKAVKAARQAFQIGSPWRTMDASERGRLLNKLADLMERDRLLLATMEALNGGKVFANAYLSDLGGCIKALKYCAGWADKIHGQTIPSDGDIFTYTRREPIGVCGQIIPWNFPMLMFIWKIGPALSCGNTVVVKPAEQTPLTALHLASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTQVGKLIKEAAGKSNLKRVTLELGGKSPCIVFADADLDIAVEFAHHGVFYHQGQCCVAASRIFVEESVYDEFV... | 9-cis-retinoic acid biosynthetic process 9-cis-retinoic acid metabolic process apoptotic process cellular detoxification of aldehyde embryonic eye morphogenesis fructosamine catabolic process fructose catabolic process gamma-aminobutyric acid biosynthetic process maintenance of lens transparency negative regulation of ... |
actin cytoskeleton organization adaptive immune response cellular response to glucocorticoid stimulus G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger granulocyte chemotaxis inflammatory response innate immune response monocyte chemotaxis negative regulation of exocytosis nega... | apical plasma membrane; basolateral plasma membrane; cytoplasm; early endosome membrane; extracellular exosome; extracellular space; lateral plasma membrane; motile cilium; nucleus; phagocytic cup; plasma membrane | calcium ion binding calcium-dependent phospholipid binding phospholipase A2 inhibitor activity | Rodentia sp | Acetylation Adaptive immunity Annexin Calcium Calcium/phospholipid-binding Cell membrane Cell projection Cilium Cytoplasm Cytoplasmic vesicle Endosome Immunity Inflammatory response Innate immunity Isopeptide bond Membrane Metal-binding Nucleus Phospholipase A2 inhibitor Phosphoprotein Repeat Secreted Ubl conjugation | MAMVSEFINQ | MAMVSEFINQACYLEKQEQEYIEIVKSYKGGPAHAVSPYPSFDPSSDVAALHKGIMVNGVDEATILDLLTKRYNAQRHHLKAVYIQETGEPLDETLKKALTGHIQELLLAMIKTPAQFDGNELRAAMKAVGTDEETLIEILWTRSNQQIREITSVYREELKKDIAKYQTSDTSGEFRDALLALAKGNRCEDMSVNQDIADTDARALYQAAERRNGTDVNVFNTILTTKKYPHLRNKFQNYRKYTEEDMKKALDIELKGQIEKCLTTIAKCGTSTPAFFAEKLYEAMKGAGTRHKTLIRIMVSRSEIDSDQIKVFYQKKYG... | actin cytoskeleton organization adaptive immune response cellular response to glucocorticoid stimulus G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger granulocyte chemotaxis inflammatory response innate immune response monocyte chemotaxis negative regulation of exocytosis nega... |
cyclooxygenase pathway icosanoid metabolic process intracellular chloride ion homeostasis positive regulation of vasoconstriction prostaglandin biosynthetic process response to ethanol response to fatty acid | cytosol; endoplasmic reticulum; endoplasmic reticulum membrane | 12-hydroxyheptadecatrienoic acid synthase activity heme binding hydroperoxy icosatetraenoate dehydratase activity iron ion binding monooxygenase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen thromboxane-A synthase activity | Homo sapiens | Alternative splicing Direct protein sequencing Disease variant Endoplasmic reticulum Fatty acid biosynthesis Fatty acid metabolism Heme Iron Isomerase Lipid biosynthesis Lipid metabolism Lyase Membrane Metal-binding Monooxygenase Oxidoreductase Prostaglandin biosynthesis Prostaglandin metabolism Reference proteome Tran... | MEALGFLKLE | MEALGFLKLEVNGPMVTVALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFFRQGFWESQMELRKLYGPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVAFGTPVDSWQAPEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLIRNVIALRDQQAAEERRRDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQHQPS... | cyclooxygenase pathway icosanoid metabolic process intracellular chloride ion homeostasis positive regulation of vasoconstriction prostaglandin biosynthetic process response to ethanol response to fatty acid cytosol; endoplasmic reticulum; endoplasmic reticulum membrane 12-hydroxyheptadecatrienoic acid synthase activit... |
pilus retraction type IV pilus-dependent motility | cytoplasm; type IV pilus | ATP binding ATP hydrolysis activity | Pseudomonas aeruginosa | 3D-structure ATP-binding Cytoplasm Fimbrium biogenesis Nucleotide-binding Reference proteome Transport | MDITELLAFS | MDITELLAFSAKQGASDLHLSAGLPPMIRVDGDVRRINLPPLEHKQVHALIYDIMNDKQRKDFEEFLETDFSFEVPGVARFRVNAFNQNRGAGAVFRTIPSKVLTMEELGMGEVFKRVSDVPRGLVLVTGPTGSGKSTTLAAMLDYLNNTKYHHILTIEDPIEFVHESKKCLVNQREVHRDTLGFSEALRSALREDPDIILVGEMRDLETIRLALTAAETGHLVFGTLHTTSAAKTIDRVVDVFPAEEKAMVRSMLSESLQSVISQTLIKKIGGGRVAAHEIMIGTPAIRNLIREDKVAQMYSAIQTGGSLGMQTLDMCL... | pilus retraction type IV pilus-dependent motility cytoplasm; type IV pilus ATP binding ATP hydrolysis activity Pseudomonas aeruginosa 3D-structure ATP-binding Cytoplasm Fimbrium biogenesis Nucleotide-binding Reference proteome Transport MDITELLAFS MDITELLAFSAKQGASDLHLSAGLPPMIRVDGDVRRINLPPLEHKQVHALIYDIMNDKQRKDFEEFLETDFS... |
gas vesicle organization regulation of DNA-templated transcription | cytoplasm; gas vesicle | DNA binding zinc ion binding | Halobacterium salinarum | Cytoplasm Gas vesicle Plasmid Reference proteome Repeat | MSVTDKRDEM | MSVTDKRDEMSTARDKFAESQQEFESYADEFAADITAKQDDVSDLVDAITDFQAEMTNTTDAFHTYGDEFAAEVDHLRADIDAQRDVIREMQDAFEAYADIFATDIADKQDIGNLLAAIEALRTEMNSTHGAFEAYADDFAADVAALRDISDLVAAIDDFQEEFIAVQDAFDNYAGDFDAEIDQLHAAIADQHDSFDATADAFAEYRDEFYRIEVEALLEAINDFQQDIGDFRAEFETTEDAFVAFARDFYGHEITAEEGAAEAEAEPVEADADVEAEAEVSPDEAGGESAGTEEEETEPAEVETAAPEVEGSPADTADE... | gas vesicle organization regulation of DNA-templated transcription cytoplasm; gas vesicle DNA binding zinc ion binding Halobacterium salinarum Cytoplasm Gas vesicle Plasmid Reference proteome Repeat MSVTDKRDEM MSVTDKRDEMSTARDKFAESQQEFESYADEFAADITAKQDDVSDLVDAITDFQAEMTNTTDAFHTYGDEFAAEVDHLRADIDAQRDVIREMQDAFEAYADIFATDIADK... |
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway chemical synaptic transmission negative regulation of adenylate cyclase activity positive regulation of calcineurin-NFAT signaling cascade positive regulation of calcium ion import across plasma membrane positive regulation of endosome to plasma ... | cytoplasmic side of plasma membrane; cytosol; dendrite membrane; dendritic spine; excitatory synapse; membrane raft; plasma membrane; postsynaptic density; postsynaptic recycling endosome; postsynaptic recycling endosome membrane; protein serine/threonine phosphatase complex | adenylate cyclase binding beta-2 adrenergic receptor binding calmodulin binding GABA receptor binding glutamate receptor binding molecular adaptor activity protein kinase A binding protein kinase A regulatory subunit binding protein phosphatase 2B binding scaffold protein binding SH3 domain binding | Homo sapiens | 3D-structure Calmodulin-binding Endosome Lipoprotein Membrane Palmitate Phosphoprotein Reference proteome Synapse | METTISEIHV | METTISEIHVENKDEKRSAEGSPGAERQKEKASMLCFKRRKKAAKALKPKAGSEAADVARKCPQEAGASDQPEPTRGAWASLKRLVTRRKRSESSKQQKPLEGEMQPAINAEDADLSKKKAKSRLKIPCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQTQTPLNDQATKAKSTQDLSEGISRKDGDEVCESNVSNSTTSGEKVISVELGLDNGHSAIQTGTLILEEIETIKEKQDVQPQQASPLETSETDHQQPVLSDVPPLPAIPDQQIVEEASNSTLESAPNGKDYESTEIVAEETKPKDTELSQESDFKEN... | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway chemical synaptic transmission negative regulation of adenylate cyclase activity positive regulation of calcineurin-NFAT signaling cascade positive regulation of calcium ion import across plasma membrane positive regulation of endosome to plasma ... |
cell migration negative regulation of canonical Wnt signaling pathway negative regulation of cell population proliferation positive regulation of MAPK cascade positive regulation of stress-activated MAPK cascade regulation of insulin-like growth factor receptor signaling pathway signal transduction | extracellular region; extracellular space; insulin-like growth factor binary complex | fibronectin binding identical protein binding insulin-like growth factor I binding insulin-like growth factor II binding signaling receptor binding | Homo sapiens | 3D-structure Direct protein sequencing Disulfide bond Glycoprotein Growth factor binding Reference proteome Secreted Signal | MTPHRLLPPL | MTPHRLLPPLLLLLALLLAASPGGALARCPGCGQGVQAGCPGGCVEEEDGGSPAEGCAEAEGCLRREGQECGVYTPNCAPGLQCHPPKDDEAPLRALLLGRGRCLPARAPAVAEENPKESKPQAGTARPQDVNRRDQQRNPGTSTTPSQPNSAGVQDTEMGPCRRHLDSVLQQLQTEVYRGAQTLYVPNCDHRGFYRKRQCRSSQGQRRGPCWCVDRMGKSLPGSPDGNGSSSCPTGSSG | cell migration negative regulation of canonical Wnt signaling pathway negative regulation of cell population proliferation positive regulation of MAPK cascade positive regulation of stress-activated MAPK cascade regulation of insulin-like growth factor receptor signaling pathway signal transduction extracellular region... |
viral entry into host cell viral penetration into host nucleus | host cell endoplasmic reticulum membrane; host cell nucleus; membrane; viral capsid | DNA binding structural molecule activity | Murine polyomavirus | Alternative initiation Alternative splicing Capsid protein DNA-binding Host endoplasmic reticulum Host membrane Host nucleus Late protein Lipoprotein Membrane Myristate Viral penetration into host nucleus Virion Virus entry into host cell | MGAFLAVLAE | MGAFLAVLAEVFDLASITGLSVESILSGEALTTAELLQSHINNLVVYGGLTEAEALAAVEVTPQAFAALTSLFPNFPQALGALAATEFTATGALTVGAAVSAALYPYYWDYRTPVADLNMALQIWYPDLDILFPGALPFARFVNYIDPANWAADLYRAVGRYFWERVQAAGINFIEQQMETGRELAMRSVTSLSETLSQYFENARWAVSGLSTSLYHGLESYYSQLGLSPIQQRQLARNLGHPQPYRYDLYDAPQLKGQVSATYVTKVDPPGGANQRSAPDWMLPLLLGLYGDLTPSWKDTLEELEAEEDGSHSQKAKRR... | viral entry into host cell viral penetration into host nucleus host cell endoplasmic reticulum membrane; host cell nucleus; membrane; viral capsid DNA binding structural molecule activity Murine polyomavirus Alternative initiation Alternative splicing Capsid protein DNA-binding Host endoplasmic reticulum Host membran... |
adaptive immune response B cell receptor signaling pathway integrin-mediated signaling pathway intracellular signal transduction phosphorylation regulation of platelet activation T cell receptor signaling pathway tissue regeneration | cell-cell junction; cytoskeleton; cytosol; plasma membrane | ATP binding lipid binding metal ion binding non-membrane spanning protein tyrosine kinase activity protein self-association | Mus musculus | 3D-structure Adaptive immunity Alternative splicing ATP-binding Cell membrane Cytoplasm Cytoskeleton Immunity Kinase Lipid-binding Membrane Metal-binding Nucleotide-binding Phosphoprotein Reference proteome SH2 domain SH3 domain Transferase Tyrosine-protein kinase Zinc Zinc-finger | MNFNTILEEI | MNFNTILEEILIKRSQQKKKTSLLNYKERLCVLPKSVLSYYEGRAEKKYRKGVIDISKIKCVEIVKNDDGVIPCQNKFPFQVVHDANTLYIFAPSPQSRDRWVKKLKEEIKNNNNIMIKYHPKFWADGSYQCCRQTEKLAPGCEKYNLFESSIRKTLPPAPEIKKRRPPPPIPPEEENTEEIVVAMYDFQATEAHDLRLERGQEYIILEKNDLHWWRARDKYGSEGYIPSNYVTGKKSNNLDQYEWYCRNTNRSKAEQLLRTEDKEGGFMVRDSSQPGLYTVSLYTKFGGEGSSGFRHYHIKETATSPKKYYLAEKHAFG... | adaptive immune response B cell receptor signaling pathway integrin-mediated signaling pathway intracellular signal transduction phosphorylation regulation of platelet activation T cell receptor signaling pathway tissue regeneration cell-cell junction; cytoskeleton; cytosol; plasma membrane ATP binding lipid binding me... |
arachidonic acid secretion defense response to bacterium lipid catabolic process phospholipid metabolic process | extracellular region | calcium ion binding heparin binding phospholipase A2 activity toxin activity | Bothrops asper | 3D-structure Antibiotic Antimicrobial Blood coagulation cascade inhibiting toxin Direct protein sequencing Disulfide bond Hemostasis impairing toxin Heparin-binding Lipoprotein Myotoxin Pharmaceutical Secreted Signal Toxin | MRTLWIMAVL | MRTLWIMAVLLVGVEGSLFELGKMILQETGKNPAKSYGAYGCNCGVLGRGKPKDATDRCCYVHKCCYKKLTGCNPKKDRYSYSWKDKTIVCGENNSCLKELCECDKAVAICLRENLNTYNKKYRYYLKPLCKKADAC | arachidonic acid secretion defense response to bacterium lipid catabolic process phospholipid metabolic process extracellular region calcium ion binding heparin binding phospholipase A2 activity toxin activity Bothrops asper 3D-structure Antibiotic Antimicrobial Blood coagulation cascade inhibiting toxin Direct protein... |
anatomical structure development cardiac muscle cell differentiation cell migration cell population proliferation developmental pigmentation heart development mammary gland specification muscle organ development myoblast migration myoblast proliferation negative regulation of transcription by RNA polymerase II neural c... | nucleoplasm; nucleus; transcription regulator complex | chromatin binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific HMG box domain binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA binding transcription coregul... | Mus musculus | Developmental protein Disease variant DNA-binding Homeobox Myogenesis Neurogenesis Nucleus Paired box Phosphoprotein Reference proteome Transcription Transcription regulation | MTTLAGAVPR | MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQA... | anatomical structure development cardiac muscle cell differentiation cell migration cell population proliferation developmental pigmentation heart development mammary gland specification muscle organ development myoblast migration myoblast proliferation negative regulation of transcription by RNA polymerase II neural c... |
detection of mechanical stimulus involved in sensory perception of touch mechanosensory behavior negative regulation of turning behavior involved in mating positive regulation of detection of mechanical stimulus involved in sensory perception of touch positive regulation of mechanosensory behavior potassium ion transpo... | axon; membrane; neuron projection membrane | ligand-gated sodium channel activity | Caenorhabditis elegans | 3D-structure Cell projection Glycoprotein Ion channel Ion transport Membrane Neurodegeneration Potassium Potassium transport Reference proteome Sodium Sodium channel Sodium transport Transmembrane Transmembrane helix Transport | MSWMQNLKNY | MSWMQNLKNYQHLRDPSEYMSQVYGDPLAYLQETTKFVTEREYYEDFGYGECFNSTESEVQCELITGEFDPKLLPYDKRLAWHFKEFCYKTSAHGIPMIGEAPNVYYRAVWVVLFLGCMIMLYLNAQSVLDKYNRNEKIVDIQLKFDTAPFPAITLCNLNPYKASLATSVDLVKRTLSAFDGAMGKAGGNKDHEEEREVVTEPPTTPAPTTKPARRRGKRDLSGAFFEPGFARCLCGSQGSSEQEDKDEEKEEELLETTTKKVFNINDADEEWDGMEEYDNEHYENYDVEATTGMNMMEECQSERTKFDEPTGFDDRCIC... | detection of mechanical stimulus involved in sensory perception of touch mechanosensory behavior negative regulation of turning behavior involved in mating positive regulation of detection of mechanical stimulus involved in sensory perception of touch positive regulation of mechanosensory behavior potassium ion transpo... |
actin filament organization apoptotic process apoptotic process involved in morphogenesis camera-type eye development embryonic camera-type eye morphogenesis lens development in camera-type eye lens fiber cell morphogenesis lens morphogenesis in camera-type eye microtubule-based process mitochondrion organization negat... | cytoplasm; cytosol; nucleoplasm; nucleus; protein-containing complex | identical protein binding metal ion binding structural constituent of eye lens structural molecule activity unfolded protein binding | Mus musculus | Acetylation Alternative splicing Chaperone Cytoplasm Eye lens protein Glycoprotein Metal-binding Methylation Nucleus Phosphoprotein Reference proteome Zinc | MDVTIQHPWF | MDVTIQHPWFKRALGPFYPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFRTVLDSGISELMTHMWFVMHQPHAGNPKNNPVKVRSDRDKFVIFLDVKHFSPEDLTVKVLEDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFSGPKVQSGLDAGHSERAIPVSREEKPSSAPSS | actin filament organization apoptotic process apoptotic process involved in morphogenesis camera-type eye development embryonic camera-type eye morphogenesis lens development in camera-type eye lens fiber cell morphogenesis lens morphogenesis in camera-type eye microtubule-based process mitochondrion organization negat... |
actin filament organization apoptotic process apoptotic process involved in morphogenesis camera-type eye development embryonic camera-type eye morphogenesis lens development in camera-type eye lens fiber cell morphogenesis lens morphogenesis in camera-type eye microtubule-based process mitochondrion organization negat... | cytoplasm; nucleus; protein-containing complex | identical protein binding metal ion binding structural constituent of eye lens structural molecule activity unfolded protein binding | Rattus norvegicus | Acetylation Alternative splicing Chaperone Cytoplasm Direct protein sequencing Eye lens protein Glycoprotein Metal-binding Methylation Nucleus Phosphoprotein Reference proteome Zinc | MDVTIQHPWF | MDVTIQHPWFKRALGPFYPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFRTVLDSGISELMTHMWFVMHQPHAGNPKNNPGKVRSDRDKFVIFLDVKHFSPEDLTVKVLEDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFSGPKVQSGLDAGHSERAIPVSREEKPSSAPSS | actin filament organization apoptotic process apoptotic process involved in morphogenesis camera-type eye development embryonic camera-type eye morphogenesis lens development in camera-type eye lens fiber cell morphogenesis lens morphogenesis in camera-type eye microtubule-based process mitochondrion organization negat... |
antibacterial humoral response antifungal humoral response bone morphogenesis innate immune response in mucosa iron ion transport negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity negative regulation of lipopolysaccharide-mediated signaling pathway negative regulation ... | early endosome; extracellular space; plasma membrane; recycling endosome; specific granule | cysteine-type endopeptidase inhibitor activity iron ion binding serine-type endopeptidase activity signaling receptor binding | Bos taurus | 3D-structure Antibiotic Antimicrobial Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Immunity Ion transport Iron Iron transport Metal-binding Osteogenesis Protease Reference proteome Repeat Secreted Serine protease Signal Transport | MKLFVPALLS | MKLFVPALLSLGALGLCLAAPRKNVRWCTISQPEWFKCRRWQWRMKKLGAPSITCVRRAFALECIRAIAEKKADAVTLDGGMVFEAGRDPYKLRPVAAEIYGTKESPQTHYYAVAVVKKGSNFQLDQLQGRKSCHTGLGRSAGWIIPMGILRPYLSWTESLEPLQGAVAKFFSASCVPCIDRQAYPNLCQLCKGEGENQCACSSREPYFGYSGAFKCLQDGAGDVAFVKETTVFENLPEKADRDQYELLCLNNSRAPVDAFKECHLAQVPSHAVVARSVDGKEDLIWKLLSKAQEKFGKNKSRSFQLFGSPPGQRDLLFK... | antibacterial humoral response antifungal humoral response bone morphogenesis innate immune response in mucosa iron ion transport negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity negative regulation of lipopolysaccharide-mediated signaling pathway negative regulation ... |
microtubule cytoskeleton organization microtubule polymerization mitotic cell cycle nuclear division nuclear migration by microtubule mediated pushing forces | cytoplasm; cytoplasmic microtubule; microtubule; nucleus; spindle; tubulin complex | GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton | Emericella nidulans | Cytoplasm Cytoskeleton GTP-binding Hydrolase Magnesium Metal-binding Microtubule Nucleotide-binding Reference proteome | MREVISLNVG | MREVISLNVGQAGCQIANSCWELYCLEHGIQPDGYLTEERKKEDPDHGFSTFFSETGQGKYVPRTIYADLEPNVVDEVRTGTYRSLFHPENLITGKEDASNNYARGHYTVGKEMIDQVLDKVRRMADSCSGLQGFLVFHSFGGGTGSGFGALLMERLSVDYGKKSKLEFCVYPAPQNATSVVEPYNSILTTHTTLEHSDCSFMVDNEAIYDICRRNLGIERPSYENLNRLIAQVVSSITASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVAYSPVISADKASHEANSVQDITMSCFEPNNQMVKCDPRNGKYMATCLLYR... | microtubule cytoskeleton organization microtubule polymerization mitotic cell cycle nuclear division nuclear migration by microtubule mediated pushing forces cytoplasm; cytoplasmic microtubule; microtubule; nucleus; spindle; tubulin complex GTP binding hydrolase activity metal ion binding structural constituent of cyto... |
microtubule-based process | chloroplast stroma; cytosol; Golgi apparatus; microtubule; plant-type cell wall; plasma membrane; plasmodesma; plastid; tubulin complex | GTP binding GTPase activity metal ion binding mRNA binding structural constituent of cytoskeleton | Arabidopsis thaliana | Cytoplasm Cytoskeleton GTP-binding Magnesium Metal-binding Microtubule Nucleotide-binding Reference proteome | MREILHIQGG | MREILHIQGGQCGNQIGAKFWEVICDEHGIDHTGQYVGDSPLQLERIDVYFNEASGGKYVPRAVLMDLEPGTMDSLRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELIDSVLDVVRKEAENSDCLQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMMTFSVFPSPKVSDTVVEPYNATLSVHQLVENADECMVLDNEALYDICFRTLKLANPTFGDLNHLISATMSGVTCCLRFPGQLNSDLRKLAVNLIPFPRLHFFMVGFAPLTSRGSQQYSALSVPELTQQMWDAKNMMCAADPRHGRYLTASAVFRGK... | microtubule-based process chloroplast stroma; cytosol; Golgi apparatus; microtubule; plant-type cell wall; plasma membrane; plasmodesma; plastid; tubulin complex GTP binding GTPase activity metal ion binding mRNA binding structural constituent of cytoskeleton Arabidopsis thaliana Cytoplasm Cytoskeleton GTP-binding Magn... |
intracellular calcium ion homeostasis plasma membrane repair response to bacterium response to wounding sorocarp development | cytoplasm; endosome membrane; nucleus; phagocytic vesicle; plasma membrane | calcium ion binding calcium-dependent phospholipid binding phosphatidylserine binding | Dictyostelium discoideum | Alternative splicing Annexin Calcium Calcium/phospholipid-binding Direct protein sequencing Reference proteome Repeat | MSYPPNQGYP | MSYPPNQGYPPQSNSPQPGQYGAPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQGYPPQQGYPPVGVPVGVPVGFAPGMVVGYHQGYFVGTITHDCKHDAEVLRKAMKGIGTNESDLIKVLANRNWAEREQIKREFSAKYSKDLIQDIKSETSGNFEKCLVALLTEPAHFDVEQIHSACAGAGTNENTIIEILVTRSNVQMEYIKQIFKNKHGKSLKDRLESEASGDFKKLLEKLTEPRDESPVINPMQVSKD... | intracellular calcium ion homeostasis plasma membrane repair response to bacterium response to wounding sorocarp development cytoplasm; endosome membrane; nucleus; phagocytic vesicle; plasma membrane calcium ion binding calcium-dependent phospholipid binding phosphatidylserine binding Dictyostelium discoideum Alternati... |
clathrin-dependent endocytosis protein folding synaptic vesicle endocytosis ubiquitin-dependent ERAD pathway | endoplasmic reticulum; endoplasmic reticulum membrane; melanosome membrane; mitochondrial membrane; presynapse | calcium ion binding carbohydrate binding unfolded protein binding | Canis lupus familiaris | 3D-structure Acetylation Calcium Chaperone Direct protein sequencing Disulfide bond Endoplasmic reticulum Lectin Lipoprotein Membrane Metal-binding Mitochondrion Palmitate Phosphoprotein Reference proteome Repeat Signal Transmembrane Transmembrane helix Ubl conjugation | MEGKWLLCML | MEGKWLLCMLLVLGTTIVQAHEGHDDDMIDIEDDLDDVIEEVEDSKSKPDTSAPTSPKVTYKAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVDEMKETKLPGDKGLVLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFHDKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGVYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEILVDQSIVNSGNLLNDMTPPVNPSREIEDPEDQKPEDWDERPKIPDPDAVKPDDWNEDAPAKIPDEEATK... | clathrin-dependent endocytosis protein folding synaptic vesicle endocytosis ubiquitin-dependent ERAD pathway endoplasmic reticulum; endoplasmic reticulum membrane; melanosome membrane; mitochondrial membrane; presynapse calcium ion binding carbohydrate binding unfolded protein binding Canis lupus familiaris 3D-structu... |
intracellular protein transport lysosomal transport protein targeting to lysosome secretion of lysosomal enzymes | endosome; late endosome; lysosomal membrane; perinuclear region of cytoplasm; trans-Golgi network | protein domain specific binding retromer complex binding | Mus musculus | Disulfide bond Glycoprotein Lysosome Membrane Phosphoprotein Receptor Reference proteome Signal Transmembrane Transmembrane helix Transport | MFPFSGCWRT | MFPFSGCWRTELLLLLLLAVAVRESWQIEEKSCDLVGEKDKESKNEVALLERLRPLFNKSFESTVGQGSDTYSYIFRVCREASNHSSGAGLVQINKSNDKETVVGRINETHIFNGSNWIMLIYKGGDEYDNHCGKEQRRAVVMISCNRHTLAANFNPVSEERGKVQDCFYLFEMDSSLACSPEVSHLSVGSILLVIFASLVAVYIIGGFLYQRLVVGAKGMEQFPHLAFWQDLGNLVADGCDFVCRSKPRNVPAAYRGVGDDQLGEESEERDDHLLPM | intracellular protein transport lysosomal transport protein targeting to lysosome secretion of lysosomal enzymes endosome; late endosome; lysosomal membrane; perinuclear region of cytoplasm; trans-Golgi network protein domain specific binding retromer complex binding Mus musculus Disulfide bond Glycoprotein Lysosome Me... |
camera-type eye development cartilage condensation embryonic skeletal system morphogenesis extracellular matrix organization muscle organ development muscle organ morphogenesis muscle tissue morphogenesis ossification positive regulation of myoblast differentiation positive regulation of skeletal muscle fiber developme... | nucleoplasm; nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding | Mus musculus | Activator Developmental protein Differentiation DNA-binding Myogenesis Nucleus Reference proteome Transcription Transcription regulation | MDMTDGCQFS | MDMTDGCQFSPSEYFYEGSCIPSPEDEFGDQFEPRVAAFGAHKAELQGSDDEEHVRAPTGHHQAGHCLMWACKACKRKSTTMDRRKAATMRERRRLKKVNQAFETLKRCTTTNPNQRLPKVEILRNAIRYIESLQELLREQVENYYSLPGQSCSEPTSPTSNCSDGMPECNSPVWSRKNSSFDSIYCPDVSNACAADKSSVSSLDCLSSIVDRITSTEPSELALQDTASLSPATSANSQPATPGPSSSRLIYHVL | camera-type eye development cartilage condensation embryonic skeletal system morphogenesis extracellular matrix organization muscle organ development muscle organ morphogenesis muscle tissue morphogenesis ossification positive regulation of myoblast differentiation positive regulation of skeletal muscle fiber developme... |
cellular response to copper ion cellular response to light intensity cellular response to oxidative stress cellular response to ozone cellular response to salt stress cellular response to sucrose stimulus cellular response to UV-B defense response to bacterium miRNA-mediated post-transcriptional gene silencing response... | cytosol; nucleus | copper ion binding superoxide dismutase activity | Arabidopsis thaliana | Antioxidant Copper Cytoplasm Disulfide bond Metal-binding Nucleus Oxidoreductase Reference proteome Zinc | MAKGVAVLNS | MAKGVAVLNSSEGVTGTIFFTQEGDGVTTVSGTVSGLKPGLHGFHVHALGDTTNGCMSTGPHFNPDGKTHGAPEDANRHAGDLGNITVGDDGTATFTITDCQIPLTGPNSIVGRAVVVHADPDDLGKGGHELSLATGNAGGRVACGIIGLQG | cellular response to copper ion cellular response to light intensity cellular response to oxidative stress cellular response to ozone cellular response to salt stress cellular response to sucrose stimulus cellular response to UV-B defense response to bacterium miRNA-mediated post-transcriptional gene silencing response... |
bone mineralization endocytosis glycoprotein metabolic process lipid homeostasis regulation of protein stability | endoplasmic reticulum quality control compartment; external side of plasma membrane; perinuclear region of cytoplasm | fucose binding mannose binding | Mus musculus | Calcium Disulfide bond Endocytosis Glycoprotein Lectin Lipoprotein Membrane Palmitate Phosphoprotein Receptor Reference proteome Signal-anchor Transmembrane Transmembrane helix | MEKDCQDIQQ | MEKDCQDIQQLDSEENDHQLSGDDEHGSHVQDPRIENPHWKGQPLSRPFPQRLCSTFRLSLLALAFNILLLVVICVVSSQSIQLQEEFRTLKETFSNFSSSTLMEFGALDTLGGSTNAILTSWLAQLEEKQQQLKADHSTLLFHLKHFPMDLRTLTCQLAYFQSNGTECCPVNWVEFGGSCYWFSRDGLTWAEADQYCQLENAHLLVINSREEQDFVVKHRSQFHIWIGLTDRDGSWKWVDGTDYRSNYRNWAFTQPDNWQGHEQGGGEDCAEILSDGHWNDNFCQQVNRWVCEKRRNITH | bone mineralization endocytosis glycoprotein metabolic process lipid homeostasis regulation of protein stability endoplasmic reticulum quality control compartment; external side of plasma membrane; perinuclear region of cytoplasm fucose binding mannose binding Mus musculus Calcium Disulfide bond Endocytosis Glycoprotei... |
cell differentiation intracellular signal transduction negative regulation of glial cell apoptotic process positive regulation of B cell receptor signaling pathway positive regulation of glial cell proliferation positive regulation of keratinocyte differentiation positive regulation of macrophage derived foam cell diff... | cell-cell junction; cytoplasm; cytosol; extracellular exosome; plasma membrane | ATP binding diacylglycerol-dependent serine/threonine kinase activity diacylglycerol-dependent, calcium-independent serine/threonine kinase activity enzyme binding metal ion binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity small GTPase binding | Homo sapiens | 3D-structure Alternative splicing ATP-binding Cytoplasm Differentiation Kinase Metal-binding Nucleotide-binding Phosphoprotein Reference proteome Repeat Serine/threonine-protein kinase Transferase Zinc Zinc-finger | MSSGTMKFNG | MSSGTMKFNGYLRVRIGEAVGLQPTRWSLRHSLFKKGHQLLDPYLTVSVDQVRVGQTSTKQKTNKPTYNEEFCANVTDGGHLELAVFHETPLGYDHFVANCTLQFQELLRTTGASDTFEGWVDLEPEGKVFVVITLTGSFTEATLQRDRIFKHFTRKRQRAMRRRVHQINGHKFMATYLRQPTYCSHCREFIWGVFGKQGYQCQVCTCVVHKRCHHLIVTACTCQNNINKVDSKIAEQRFGINIPHKFSIHNYKVPTFCDHCGSLLWGIMRQGLQCKICKMNVHIRCQANVAPNCGVNAVELAKTLAGMGLQPGNISPTS... | cell differentiation intracellular signal transduction negative regulation of glial cell apoptotic process positive regulation of B cell receptor signaling pathway positive regulation of glial cell proliferation positive regulation of keratinocyte differentiation positive regulation of macrophage derived foam cell diff... |
viral budding via host ESCRT complex | host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane | RNA binding structural molecule activity zinc ion binding | Human immunodeficiency virus type 1 group M subtype A | 3D-structure AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Methylation Myristate Phosphoprotein Reference proteome Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexe... | MGARASVLSG | MGARASVLSGKKLDSWEKIRLRPGGNKKYRLKHLVWASRELEKFTLNPGLLETAEGCQQILGQLQPALQTGTEELRSLYNTVAVLYCVHQRIDVKDTKEALNKIEEMQNKNKQRTQQAAANTGSSQNYPIVQNAQGQPVHQALSPRTLNAWVKVVEDKAFSPEVIPMFSALSEGATPQDLNMMLNVVGGHQAAMQMLKDTINEEAAEWDRLHPVHAGPIPPGQMREPRGSDIAGTTSTVQEQIGWMTGNPPIPVGDIYRRWIILGLNKIVRMYSPVSILDIRQGPKEPFRDYVDRFFKTLRAEQATQDVKNWMTETLLVQ... | viral budding via host ESCRT complex host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane RNA binding structural molecule activity zinc ion binding Human immunodeficiency virus type 1 group M subtype A 3D-structure AIDS Capsid protein Host cell membrane ... |
DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by viru... | extracellular region; host cell cytoplasm; host cell nucleolus | actinin binding cyclin binding metal ion binding protein domain specific binding protein serine/threonine phosphatase inhibitor activity RNA-binding transcription regulator activity trans-activation response element binding | Human immunodeficiency virus type 1 group M subtype A | Acetylation Activator AIDS Alternative splicing Apoptosis Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Isopeptide bond Metal-binding Methylation Modulation of host chromatin by virus Modulation of host PP1 ... | MEPVDPNLEP | MEPVDPNLEPWKHPGSQPTTACSNCYCKVCCWHCQLCFLKKGLGISYGKKKRKPRRGPPQGSKDHQTLIPKQPLPQSQRVSAGQEESKKKVESKAKTDRFA | DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by viru... |
suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy | extracellular region; host cell Golgi membrane; host cell plasma membrane; membrane; virion component | GTP binding SH3 domain binding | Human immunodeficiency virus type 1 group M subtype A | AIDS Apoptosis Early protein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host autophagy by virus Inhibition of host MHC class I molecule presentation by virus Inhibition of host MHC class II molecule presentation by viru... | MGGKWSKKSR | MGGKWSKKSRVEWPEVRKRMRETPAAAKGVGAVSQDLDKYGAVTSSNTSSTNASCAWLEAQEEGDVGFPVRPQVPLRPMTYKAAFDLSFFLKEKGGLDGLIHSQKRQEILDLWVYHTQGFFPDWQNYTPGPGIRYPLTFGWCYKLVPVDPAEVEEATGGENNSLLHPICQHGVDDEEKEVLMWKFDSTLALKHRAYELHPEFYKD | suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy extracellular region; host cell Golgi membrane; host cell plasma membrane; membr... |
acetyl-CoA biosynthetic process acetyl-CoA catabolic process adipose tissue development coenzyme A biosynthetic process coenzyme A metabolic process fatty acid beta-oxidation isoleucine catabolic process ketone body catabolic process ketone body metabolic process liver development metanephric proximal convoluted tubule... | endoplasmic reticulum; extracellular exosome; mitochondrial matrix; mitochondrion | acetyl-CoA C-acetyltransferase activity C-acetyltransferase activity cholesterol O-acyltransferase activity coenzyme A binding enzyme binding identical protein binding potassium ion binding | Homo sapiens | 3D-structure Acetylation Acyltransferase Alternative splicing Direct protein sequencing Disease variant Fatty acid metabolism Lipid metabolism Metal-binding Mitochondrion Potassium Reference proteome Transferase Transit peptide | MAVLAALLRS | MAVLAALLRSGARSRSPLLRRLVQEIRYVERSYVSKPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAV... | acetyl-CoA biosynthetic process acetyl-CoA catabolic process adipose tissue development coenzyme A biosynthetic process coenzyme A metabolic process fatty acid beta-oxidation isoleucine catabolic process ketone body catabolic process ketone body metabolic process liver development metanephric proximal convoluted tubule... |
cellular response to fibroblast growth factor stimulus determination of left/right symmetry embryonic axis specification positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II | nucleus | DNA-binding transcription factor activity RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II-specific DNA-binding transcription factor binding | Xenopus laevis | 3D-structure Activator Developmental protein DNA-binding Nucleus Reference proteome Transcription Transcription regulation | MSATESCAKN | MSATESCAKNVQYRVDHLLSAVENELQAGSEKGDPTEKELKVSLEERDLWTRFKELTNEMIVTKNGRRMFPVLKVSMSGLDPNAMYTVLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKDPVSFSKVKLTNKMNGGGQIMLNSLHKYEPRIHIVRVGGTQRMITSHSFPETQFIAVTAYQNEEITALKIKHNPFAKAFLDAKERNDYKDILDEGIDSQHSNFSQLGTWLIPNGGSLCSPNPHTQFGAPLSLSSPHGCERYSSLRNHRSAPYPSPYTHRNNSPNNLADNSSACLSMLQSHDNWS... | cellular response to fibroblast growth factor stimulus determination of left/right symmetry embryonic axis specification positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II nucleus DNA-binding transcription factor activity RNA polymerase II cis-regulatory region ... |
messenger ribonucleoprotein complex assembly nuclear polyadenylation-dependent mRNA catabolic process nuclear-transcribed mRNA catabolic process, nonsense-mediated decay rRNA processing termination of RNA polymerase II transcription | cytoplasm; mitochondrion; nucleus; ribonucleoprotein complex | ATP binding ATP hydrolysis activity ATP-dependent activity, acting on RNA mRNA binding RNA binding RNA helicase activity snoRNA binding | Saccharomyces cerevisiae | 3D-structure ATP-binding Cytoplasm Helicase Hydrolase Isopeptide bond Methylation Nonsense-mediated mRNA decay Nucleotide-binding Nucleus Phosphoprotein Reference proteome Ribosome biogenesis RNA-binding rRNA processing Ubl conjugation | MTYGGRDQQY | MTYGGRDQQYNKTNYKSRGGDFRGGRNSDRNSYNDRPQGGNYRGGFGGRSNYNQPQELIKPNWDEELPKLPTFEKNFYVEHESVRDRSDSEIAQFRKENEMTISGHDIPKPITTFDEAGFPDYVLNEVKAEGFDKPTGIQCQGWPMALSGRDMVGIAATGSGKTLSYCLPGIVHINAQPLLAPGDGPIVLVLAPTRELAVQIQTECSKFGHSSRIRNTCVYGGVPKSQQIRDLSRGSEIVIATPGRLIDMLEIGKTNLKRVTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVKQLAADYLNDPIQVQ... | messenger ribonucleoprotein complex assembly nuclear polyadenylation-dependent mRNA catabolic process nuclear-transcribed mRNA catabolic process, nonsense-mediated decay rRNA processing termination of RNA polymerase II transcription cytoplasm; mitochondrion; nucleus; ribonucleoprotein complex ATP binding ATP hydrolysis... |
positive regulation of formation of translation preinitiation complex translational initiation | cytoplasm; nucleus | ATP binding ATP hydrolysis activity DNA/RNA helicase activity mRNA binding RNA binding RNA helicase activity single-stranded RNA binding translation initiation factor activity | Saccharomyces cerevisiae | ATP-binding Cytoplasm Helicase Hydrolase Initiation factor Nucleotide-binding Protein biosynthesis Reference proteome RNA-binding | MADLPQKVSN | MADLPQKVSNLSINNKENGGGGGKSSYVPPHLRSRGKPSFERSTPKQEDKVTGGDFFRRAGRQTGNNGGFFGFSKERNGGTSANYNRGGSSNYKSSGNRWVNGKHIPGPKNAKLEAELFGVHDDPDYHSSGIKFDNYDNIPVDASGKDVPEPILDFSSPPLDELLMENIKLASFTKPTPVQKYSIPIVTKGRDLMACAQTGSGKTGGFLFPLFTELFRSGPSPVPEKAQSFYSRKGYPSALVLAPTRELATQIFEEARKFTYRSWVRPCVVYGGAPIGNQMREVDRGCDLLVATPGRLNDLLERGKVSLANIKYLVLDEA... | positive regulation of formation of translation preinitiation complex translational initiation cytoplasm; nucleus ATP binding ATP hydrolysis activity DNA/RNA helicase activity mRNA binding RNA binding RNA helicase activity single-stranded RNA binding translation initiation factor activity Saccharomyces cerevisiae ATP-... |
cell differentiation cellular response to nerve growth factor stimulus heart development nervous system development phosphorylation positive regulation of neuron projection development positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction regulation of phosphatidylinositol 3-kinase/p... | axon; plasma membrane; receptor complex | ATP binding neurotrophin binding neurotrophin receptor activity transmembrane receptor protein tyrosine kinase activity | Sus scrofa | ATP-binding Developmental protein Differentiation Disulfide bond Glycoprotein Immunoglobulin domain Kinase Leucine-rich repeat Membrane Neurogenesis Nucleotide-binding Phosphoprotein Receptor Reference proteome Repeat Signal Transferase Transmembrane Transmembrane helix Tyrosine-protein kinase | MDVSLCPAKC | MDVSLCPAKCSFWRIFLLGSVWLDYVGSVLACPANCVCSKTEINCRRPDDGNLFPLLEGQDSGNSNGNASINITDISRNITSIHIENWRGLHTLNAVDMELYTGLQKLTIKNSGLRSIQPRAFAKNPHLRYINLSSNRLTTLSWQLFQTLSLRELRLEQNFFNCSCDIRWMQLWQEQGEAKLNSQSLYCISADGSQLPLFRMNISQCDLPEISVSHVNLTVREGDNAVVTCNGSGSPLPDVDWIVTGLQSINTHQTNLNWTNVHAINLTLVNVTSEDNGFTLTCIAENVVGMSNASVALTVHYPPRVVSLEEPELRLEHC... | cell differentiation cellular response to nerve growth factor stimulus heart development nervous system development phosphorylation positive regulation of neuron projection development positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction regulation of phosphatidylinositol 3-kinase/p... |
blastocyst development cell cycle negative regulation of apoptotic signaling pathway phosphorylation regulation of apoptotic process regulation of cell cycle regulation of centrosome cycle regulation of mitotic cell cycle regulation of mitotic nuclear division regulation of RNA splicing | cyclin-dependent protein kinase holoenzyme complex; nucleoplasm; nucleus | ATP binding cyclin-dependent protein serine/threonine kinase activity protein serine kinase activity protein serine/threonine kinase activity | Mus musculus | Alternative initiation ATP-binding Cell cycle Isopeptide bond Kinase Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase Ubl conjugation | MGDEKDSWKV | MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKLREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREEYSDKGKVGHWSRSPLRPPRERFEMGDNRKPVKEEKVEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEEGSTSEESEEEEEEEEE... | blastocyst development cell cycle negative regulation of apoptotic signaling pathway phosphorylation regulation of apoptotic process regulation of cell cycle regulation of centrosome cycle regulation of mitotic cell cycle regulation of mitotic nuclear division regulation of RNA splicing cyclin-dependent protein kinase ... |
intracellular potassium ion homeostasis intracellular sodium ion homeostasis neurotransmitter uptake potassium ion import across plasma membrane proton transmembrane transport regulation of striated muscle contraction sodium ion export across plasma membrane | cell projection; cytoplasm; plasma membrane; sodium:potassium-exchanging ATPase complex | ATP binding ATP hydrolysis activity metal ion binding P-type sodium:potassium-exchanging transporter activity | Gallus gallus | ATP-binding Cell membrane Ion transport Magnesium Membrane Metal-binding Nucleotide-binding Phosphoprotein Potassium Potassium transport Reference proteome Sodium Sodium transport Sodium/potassium transport Translocase Transmembrane Transmembrane helix Transport | MDGREYSPAA | MDGREYSPAATTSENGGGRRKQKEKELDELKKEVNLDDHKLSLDELGRKYQVDLSRGLSNARAAEVLAQDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKIQINAENVVVGDLVEVKGGDRVPADMRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVISTGDRTVMGRIASLASGLEVGRTPIAMEIEHFIRLITGVAVFLGLSFFILSLILGYTWLEAVIFLI... | intracellular potassium ion homeostasis intracellular sodium ion homeostasis neurotransmitter uptake potassium ion import across plasma membrane proton transmembrane transport regulation of striated muscle contraction sodium ion export across plasma membrane cell projection; cytoplasm; plasma membrane; sodium:potassium... |
peptidyl-lysine hydroxylation | endoplasmic reticulum; rough endoplasmic reticulum membrane | iron ion binding L-ascorbic acid binding procollagen-lysine 5-dioxygenase activity | Gallus gallus | Dioxygenase Direct protein sequencing Endoplasmic reticulum Glycoprotein Iron Membrane Metal-binding Oxidoreductase Reference proteome Signal Vitamin C | MVPPAVLLPW | MVPPAVLLPWVVLPLLGVQGGSGSKQEENLLVLTVATKQTEGFRRFRRSAQFFNYKIQVLGLDEEWKGGDDKKPAGGGQKVRLLKSALKQHADKEDLVILFIESYDVLFASGPTELLKKFKQAKSKVVFSAENYIYPDRKLEAKYPPVRDGKRFLGSGGFIGYAPNLKKLVEEWKGKDDDSDQLFYTKIFLDPEKRENINISLDHRSRIFQNLNGALDEVVLKFENARVRARNLLYDTLPVIIHGNGPTKLQLNYLGNYIPQIWTFETGCTVCDEGLRSLTGIKDEALPMILIGIFIEQPTPFLSQFFLRLRNLHYPKQR... | peptidyl-lysine hydroxylation endoplasmic reticulum; rough endoplasmic reticulum membrane iron ion binding L-ascorbic acid binding procollagen-lysine 5-dioxygenase activity Gallus gallus Dioxygenase Direct protein sequencing Endoplasmic reticulum Glycoprotein Iron Membrane Metal-binding Oxidoreductase Reference proteom... |
cell wall biogenesis plant-type cell wall loosening plant-type cell wall organization or biogenesis xyloglucan metabolic process | apoplast; cytoplasm; Golgi apparatus; plant-type cell wall; plasma membrane; secretory vesicle | hydrolase activity, hydrolyzing O-glycosyl compounds polysaccharide binding xyloglucan:xyloglucosyl transferase activity | Arabidopsis thaliana | Apoplast Cell wall Cell wall biogenesis/degradation Disulfide bond Glycoprotein Glycosidase Hydrolase Reference proteome Secreted Signal Transferase | MSPFKIFFFT | MSPFKIFFFTTLLVAAFSVSAADFNTDVNVAWGNGRGKILNNGQLLTLSLDKSSGSGFQSKTEYLFGKIDMQIKLVPGNSAGTVTTFYLKSEGSTWDEIDFEFLGNMSGDPYTLHTNVYTQGKGDKEQQFHLWFDPTANFHTYSILWNPQRIILTVDDTPIREFKNYESLGVLFPKNKPMRMYASLWNADDWATRGGLVKTDWSKAPFMASYRNIKIDSKPNSNWYTQEMDSTSQARLKWVQKNYMIYNYCTDHRRFPQGAPKECTTSS | cell wall biogenesis plant-type cell wall loosening plant-type cell wall organization or biogenesis xyloglucan metabolic process apoplast; cytoplasm; Golgi apparatus; plant-type cell wall; plasma membrane; secretory vesicle hydrolase activity, hydrolyzing O-glycosyl compounds polysaccharide binding xyloglucan:xylogluco... |
positive regulation of transcription by RNA polymerase II response to cadmium ion | cytoplasm; nucleus; RNA polymerase II transcription regulator complex | DNA-binding transcription activator activity, RNA polymerase II-specific transcription cis-regulatory region binding | Saccharomyces cerevisiae | Activator Cadmium resistance Cytoplasm Disulfide bond DNA-binding Nucleus Reference proteome Transcription Transcription regulation | MGNILRKGQQ | MGNILRKGQQIYLAGDMKKQMLLNKDGTPKRKVGRPGRKRIDSEAKSRRTAQNRAAQRAFRDRKEAKMKSLQERVELLEQKDAQNKTTTDFLLCSLKSLLSEITKYRAKNSDDERILAFLDDLQEQQKRENEKGTSTAVSKAAKELPSPNSDENMTVNTSIEVQPHTQENEKVMWNIGSWNAPSLTNSWDSPPGNRTGAVTIGDESINGSEMPDFSLDLVSNDRQTGLEALDYDIHNYFPQHSERLTAEKIDTSACQCEIDQKYLPYETEDDTLFPSVLPLAVGSQCNNICNRKCIGTKPCSNKEIKCDLITSHLLNQKS... | positive regulation of transcription by RNA polymerase II response to cadmium ion cytoplasm; nucleus; RNA polymerase II transcription regulator complex DNA-binding transcription activator activity, RNA polymerase II-specific transcription cis-regulatory region binding Saccharomyces cerevisiae Activator Cadmium resista... |
C21-steroid hormone metabolic process hippocampus development response to corticosterone steroid biosynthetic process | cytoplasm; endoplasmic reticulum; endoplasmic reticulum membrane; intercellular bridge; intracellular membrane-bounded organelle; mitochondrial crista; mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrion; nucleolus | 3-beta-hydroxy-delta5-steroid dehydrogenase activity 3-keto sterol reductase activity 5alpha-androstane-3beta,17beta-diol dehydrogenase activity cholesterol dehydrogenase activity dihydrotestosterone 17-beta-dehydrogenase activity NAD binding oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as ... | Mus musculus | Endoplasmic reticulum Isomerase Lipid metabolism Membrane Mitochondrion Multifunctional enzyme NAD NADP Oxidoreductase Reference proteome Steroid metabolism Steroidogenesis Transmembrane Transmembrane helix | MAGWSCLVTG | MAGWSCLVTGAGGFVGQRIIKMLVQEKELQEVRALDKVFRPETKEEFSKLQTKTKVTVLEGDILDAQCLRRACQGISVVIHTAAVIDVTGVIPRQTILDVNLKGTQNLLEACVQASVPAFIFCSSVDVAGPNSYKKIVLNGHEEQNHESTWSDPYPYSKKMAEKAVLAANGSMLKNGGTLNTCALRPMYIYGERSPFIFNAIIRALKNKGILCVTGKFSIANPVYVENVAWAHILAARGLRDPKKSTSIQGQFYYISDDTPHQSYDDLNYTLSKEWGLRPNASWSLPLPLLYWLAFLLETVSFLLRPVYRYRPLFNRHLI... | C21-steroid hormone metabolic process hippocampus development response to corticosterone steroid biosynthetic process cytoplasm; endoplasmic reticulum; endoplasmic reticulum membrane; intercellular bridge; intracellular membrane-bounded organelle; mitochondrial crista; mitochondrial inner membrane; mitochondrial interm... |
dephosphorylation multicellular organism growth neural tube development neurogenesis post-anal tail morphogenesis | brush border; external side of plasma membrane; plasma membrane | alkaline phosphatase activity magnesium ion binding protease binding zinc ion binding | Mus musculus | Calcium Cell membrane Disulfide bond Glycoprotein GPI-anchor Hydrolase Lipoprotein Magnesium Membrane Metal-binding Reference proteome Signal Zinc | MQGPWVLLLL | MQGPWVLLLLGLRLQLSLSVIPVEEENPAFWNKKAAEALDAAKKLQPIQTSAKNLIIFLGDGMGVPTVTATRILKGQLEGHLGPETPLAMDRFPYMALSKTYSVDRQVPDSASTATAYLCGVKTNYKTIGLSAAARFDQCNTTFGNEVFSVMYRAKKAGKSVGVVTTTRVQHASPSGTYVHTVNRNWYGDADMPASALREGCKDIATQLISNMDINVILGGGRKYMFPAGTPDPEYPNDANETGTRLDGRNLVQEWLSKHQGSQYVWNREQLIQKAQDPSVTYLMGLFEPVDTKFDIQRDPLMDPSLKDMTETAVKVLSR... | dephosphorylation multicellular organism growth neural tube development neurogenesis post-anal tail morphogenesis brush border; external side of plasma membrane; plasma membrane alkaline phosphatase activity magnesium ion binding protease binding zinc ion binding Mus musculus Calcium Cell membrane Disulfide bond Glycop... |
dephosphorylation | myofibril; plasma membrane; side of membrane | alkaline phosphatase activity metal ion binding protease binding | Mus musculus | Calcium Cell membrane Disulfide bond Glycoprotein GPI-anchor Hydrolase Lipoprotein Magnesium Membrane Metal-binding Reference proteome Signal Zinc | MWGACLLLLG | MWGACLLLLGLSLQVCPSVIPVEEENPAFWNRKAAEALDAAKKLKPIQTSAKNLVILMGDGMGVSTVTATRILKGQQQGHLGPETQLAMDRFPHMALSKTYNTDKQIPDSAGTGTAFLCGVKTNMKVIGLSAAARFNQCNTTWGNEVVSVMHRAKKAGKSVGVVTTTSVQHASPAGTYAHTVNRGWYSDAQMPASALQDGCKDISTQLISNMDIDVILGGGRKFMFPKGTPDQEYPTDTKQAGTRLDGRNLVQEWLAKHQGARYVWNRSELIQASLNRSVTHLMGLFEPNDMKYEIHRDPAQDPSLAEMTEVAVRMLSRN... | dephosphorylation myofibril; plasma membrane; side of membrane alkaline phosphatase activity metal ion binding protease binding Mus musculus Calcium Cell membrane Disulfide bond Glycoprotein GPI-anchor Hydrolase Lipoprotein Magnesium Membrane Metal-binding Reference proteome Signal Zinc MWGACLLLLG MWGACLLLLGLSLQVCPSVIP... |
myofibril assembly platelet aggregation regulation of muscle contraction | cell cortex; cytoplasm; cytosol; muscle myosin complex; myofibril; stress fiber; Z disc | calcium ion binding myosin heavy chain binding structural constituent of muscle | Homo sapiens | Acetylation Alternative splicing Calcium Cytoplasm Cytoskeleton Metal-binding Motor protein Muscle protein Myosin Phosphoprotein Reference proteome Repeat | MSSKRAKAKT | MSSKRAKAKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDEYLEGMMSEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLRELLTTMGDRFTDEEVDEMYREAPIDKKGNFNYVEFTRILKHGAKDKDD | myofibril assembly platelet aggregation regulation of muscle contraction cell cortex; cytoplasm; cytosol; muscle myosin complex; myofibril; stress fiber; Z disc calcium ion binding myosin heavy chain binding structural constituent of muscle Homo sapiens Acetylation Alternative splicing Calcium Cytoplasm Cytoskeleton Me... |
viral entry into host cell viral penetration into host nucleus | host cell endoplasmic reticulum membrane; host cell nucleus; membrane; viral capsid | DNA binding structural molecule activity | Bovine polyomavirus | Alternative initiation Alternative splicing Capsid protein DNA-binding Host endoplasmic reticulum Host membrane Host nucleus Late protein Lipoprotein Membrane Myristate Reference proteome Transmembrane Transmembrane helix Viral penetration into host nucleus Virion Virus entry into host cell | MGALLTILAE | MGALLTILAEVFELATATGLSAEAILTGEAFTTAELLQAHIANLVEVGELSVAEALAATEVTSEAFEALQSISSVLPTAFIGVAATEGAILGSLITLTATSSALYPSTWKHSTPSANLNQEMALVPYIGDLDIFFPGAETISRFVYSIDPFRWASYLYNIVGRAVWEHLFRETRRQIAYHTTDIAGRTAQSIHHTIANFLENVRWTVSHLGTNLYSGLHNYYRQLPPLNPPQSRELARRLGVPQPDRQIFEKGEEGMKHPVSAEYVEKYGAPGGAEQRVAPDWLLPLLLGLYGDLTPAWEAEVEEEENEQDEEEYEPPQK... | viral entry into host cell viral penetration into host nucleus host cell endoplasmic reticulum membrane; host cell nucleus; membrane; viral capsid DNA binding structural molecule activity Bovine polyomavirus Alternative initiation Alternative splicing Capsid protein DNA-binding Host endoplasmic reticulum Host membrane... |
apoptotic process DNA catabolic process neutrophil activation involved in immune response regulation of acute inflammatory response regulation of neutrophil mediated cytotoxicity | extracellular exosome; extracellular region; nuclear envelope; nucleus; zymogen granule | actin binding deoxyribonuclease I activity DNA binding | Homo sapiens | 3D-structure Actin-binding Alternative splicing Apoptosis Calcium Cytoplasmic vesicle Direct protein sequencing Disulfide bond Endonuclease Glycoprotein Hydrolase Nuclease Nucleus Pharmaceutical Reference proteome Secreted Signal Systemic lupus erythematosus | MRGMKLLGAL | MRGMKLLGALLALAALLQGAVSLKIAAFNIQTFGETKMSNATLVSYIVQILSRYDIALVQEVRDSHLTAVGKLLDNLNQDAPDTYHYVVSEPLGRNSYKERYLFVYRPDQVSAVDSYYYDDGCEPCGNDTFNREPAIVRFFSRFTEVREFAIVPLHAAPGDAVAEIDALYDVYLDVQEKWGLEDVMLMGDFNAGCSYVRPSQWSSIRLWTSPTFQWLIPDSADTTATPTHCAYDRIVVAGMLLRGAVVPDSALPFNFQAAYGLSDQLAQAISDHYPVEVMLK | apoptotic process DNA catabolic process neutrophil activation involved in immune response regulation of acute inflammatory response regulation of neutrophil mediated cytotoxicity extracellular exosome; extracellular region; nuclear envelope; nucleus; zymogen granule actin binding deoxyribonuclease I activity DNA bindin... |
cell division in utero embryonic development mitotic cell cycle phase transition mitotic metaphase chromosome alignment mitotic spindle organization negative regulation of gene expression negative regulation of protein phosphorylation oocyte maturation positive regulation of attachment of spindle microtubules to kineto... | centrosome; cyclin B1-CDK1 complex; cytoplasm; cytosol; membrane; mitochondrial matrix; nucleus; outer kinetochore; spindle pole | cyclin-dependent protein serine/threonine kinase activator activity cyclin-dependent protein serine/threonine kinase regulator activity patched binding protein kinase binding protein-containing complex binding ubiquitin-like protein ligase binding | Mus musculus | Acetylation Cell cycle Cell division Cyclin Cytoplasm Cytoskeleton Mitosis Nucleus Phosphoprotein Reference proteome Ubl conjugation | MALRVTRNTK | MALRVTRNTKINAENKAKVSMAGAKRVPVTVTAASKPGLRPRTALGDIGNKVSEELQARVPLKREAKTLGTGKGTVKALPKPVEKVPVCEPEVELAEPEPEPELEHVREEKLSPEPILVDNPSPSPMETSGCAPAEEYLCQAFSDVILAVSDVDADDGADPNLCSEYVKDIYAYLRQLEEEQSVRPKYLQGREVTGNMRAILIDWLIQVQMKFRLLQETMYMTVSIIDRFMQNSCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTNNTYTKHQIRQMEMKILRVLNFSLGRPLPLHFLRRASKVGEVDVEQHTLA... | cell division in utero embryonic development mitotic cell cycle phase transition mitotic metaphase chromosome alignment mitotic spindle organization negative regulation of gene expression negative regulation of protein phosphorylation oocyte maturation positive regulation of attachment of spindle microtubules to kineto... |
G0 to G1 transition negative regulation of Notch signaling pathway positive regulation of transcription by RNA polymerase II | CKM complex; cyclin-dependent protein kinase holoenzyme complex; mediator complex; nucleoplasm; nucleus | cyclin-dependent protein serine/threonine kinase regulator activity identical protein binding | Homo sapiens | 3D-structure Activator Alternative splicing Cyclin Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation | MAGNFWQSSH | MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLSEEEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDARQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKMPKPKPPPNSEGEQGPNGSQNSSYSQS | G0 to G1 transition negative regulation of Notch signaling pathway positive regulation of transcription by RNA polymerase II CKM complex; cyclin-dependent protein kinase holoenzyme complex; mediator complex; nucleoplasm; nucleus cyclin-dependent protein serine/threonine kinase regulator activity identical protein bindi... |
cell division DNA replication initiation G1/S transition of mitotic cell cycle homologous chromosome pairing at meiosis negative regulation of transcription by RNA polymerase II positive regulation of mesenchymal stem cell proliferation protein phosphorylation regulation of cell cycle regulation of protein localization... | centrosome; cyclin E1-CDK2 complex; cytoplasm; cytosol; nucleoplasm; nucleus | cyclin-dependent protein serine/threonine kinase regulator activity kinase activity protein kinase binding | Homo sapiens | 3D-structure Alternative splicing Cell cycle Cell division Cyclin Nucleus Phosphoprotein Reference proteome Ubl conjugation | MPRERRERDA | MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQ... | cell division DNA replication initiation G1/S transition of mitotic cell cycle homologous chromosome pairing at meiosis negative regulation of transcription by RNA polymerase II positive regulation of mesenchymal stem cell proliferation protein phosphorylation regulation of cell cycle regulation of protein localization... |
cell division G1/S transition of mitotic cell cycle long-chain fatty acid metabolic process positive regulation of macroautophagy regulation of cell cycle regulation of cell division regulation of establishment or maintenance of cell polarity septin ring organization | cellular bud neck; cyclin-dependent protein kinase holoenzyme complex; cytoplasm; incipient cellular bud site; nucleus | cyclin-dependent protein serine/threonine kinase regulator activity protein kinase binding | Saccharomyces cerevisiae | Cell cycle Cell division Cyclin Cytoplasm Isopeptide bond Nucleus Phosphoprotein Reference proteome Ubl conjugation | MCEYSKALHI | MCEYSKALHILLKSPVTDDIIKFLTDTTLRVVPSSNYPTPPGSPGEKHLTRLPSLMTFITRLVRYTNVYTPTLLTAACYLNKLKRILPRDATGLPSTIHRIFLACLILSAKFHNDSSPLNKHWARYTDGLFTLEDINLMERQLLQLLNWDLRVNTEDLILDLQPLLEPIKQDLARSSDQRKRINMMMSMNRRTCAGTSPIRSNNRFKLYEKQRNVSIASDLSSATLVDSCNDLRRLKDVTNIANNTVANTNYVRTVEKWNDNVNRQSWDLEQIMSQHGF | cell division G1/S transition of mitotic cell cycle long-chain fatty acid metabolic process positive regulation of macroautophagy regulation of cell cycle regulation of cell division regulation of establishment or maintenance of cell polarity septin ring organization cellular bud neck; cyclin-dependent protein kinase h... |
cell division G2/M transition of mitotic cell cycle G2/MI transition of meiotic cell cycle mitotic cell cycle phase transition mitotic spindle organization positive regulation of mitotic spindle pole body separation regulation of meiosis I regulation of protein phosphorylation | cyclin-dependent protein kinase holoenzyme complex; cytoplasm; nucleus; spindle pole body | cyclin-dependent protein serine/threonine kinase regulator activity | Saccharomyces cerevisiae | Cell cycle Cell division Cyclin Mitosis Reference proteome | MSRSLLVENS | MSRSLLVENSRTINSNEEKGVNESQYILQKRNVPRTILGNVTNNANILQEISMNRKIGMKNFSKLNNFFPLKDDVSRADDFTSSFNDSRQGVKQEVLNNKENIPEYGYSEQEKQQCSNDDSFHTNSTALSCNRLIYSENKSISTQMEWQKKIMREDSKKKRPISTLVEQDDQKKFKLHELTTEEEVLEEYEWDDLDEEDCDDPLMVSEEVNDIFDYLHHLEIITLPNKANLYKHKNIKQNRDILVNWIIKIHNKFGLLPETLYLAINIMDRFLCEEVVQLNRLQLVGTSCLFIASKYEEIYSPSIKHFAYETDGACSVED... | cell division G2/M transition of mitotic cell cycle G2/MI transition of meiotic cell cycle mitotic cell cycle phase transition mitotic spindle organization positive regulation of mitotic spindle pole body separation regulation of meiosis I regulation of protein phosphorylation cyclin-dependent protein kinase holoenzyme... |
cell division DNA damage response G2/M transition of mitotic cell cycle mitotic cell cycle phase transition negative regulation of protein dephosphorylation positive regulation of mitotic spindle pole body separation positive regulation of protein phosphorylation regulation of mitotic spindle elongation regulation of p... | cellular bud neck; cyclin-dependent protein kinase holoenzyme complex; cytoplasm; nucleus; spindle; spindle pole body | cyclin-dependent protein serine/threonine kinase regulator activity | Saccharomyces cerevisiae | Acetylation Cell cycle Cell division Cyclin Mitosis Reference proteome | MSNPIENTEN | MSNPIENTENSQNTSSSRFLRNVQRLALNNVTNTTFQKSNANNPALTNFKSTLNSVKKEGSRIPQFTRESVSRSTAAQEEKRTLKENGIQLPKNNLLDDKENQDPSSQQFGALTSIKEGRAELPANISLQESSSAKEIIQHDPLKGVGSSTEVVHNSVENEKLHPARSQLQVRNTESETDSGKKRPISTIVEQELPKKFKVCDENGKEEYEWEDLDAEDVNDPFMVSEYVNDIFEYLHQLEVITLPKKEDLYQHRNIHQNRDILVNWLVKIHNKFGLLPETLYLAINIMDRFLGKELVQLDKLQLVGTSCLFIASKYEEV... | cell division DNA damage response G2/M transition of mitotic cell cycle mitotic cell cycle phase transition negative regulation of protein dephosphorylation positive regulation of mitotic spindle pole body separation positive regulation of protein phosphorylation regulation of mitotic spindle elongation regulation of p... |
cell division G2/M transition of mitotic cell cycle meiosis II mitotic cell cycle phase transition positive regulation of mitotic spindle pole body separation regulation of mitotic spindle assembly regulation of protein phosphorylation | cyclin-dependent protein kinase holoenzyme complex; cytoplasm; nucleus | cyclin-dependent protein serine/threonine kinase regulator activity | Saccharomyces cerevisiae | Cell cycle Cell division Cyclin Mitosis Reference proteome | MHHNSQSLSS | MHHNSQSLSSGHIRSPEDENVAPIGNLKHRTGSLSHISSAHPRVALSDVTNIVATNSSNNSISKPKVAPIKERLDSAAIIEEERLDANSVAQRKEADHNDLLTDREQEEPVEDDGESEEDEEEDQEPLLLQHYASDTLVWEHAFRTYYRTTLDPNDDDVYDVVMVAELSNEIFEYMRKLEDLYKPNPYYMDKQPELRWSFRSTLIDWIVQVHEKFQLLPETLYLCINIIDRYLCKEVVPVNKFQLVGAASLFIAAKYEEINCPTIKDFVYMSENCYSRNDLLDAERTILNGLEFELGWPGPMSFLRRISKADDYEHDTRT... | cell division G2/M transition of mitotic cell cycle meiosis II mitotic cell cycle phase transition positive regulation of mitotic spindle pole body separation regulation of mitotic spindle assembly regulation of protein phosphorylation cyclin-dependent protein kinase holoenzyme complex; cytoplasm; nucleus cyclin-depend... |
epoxygenase P450 pathway naphthalene catabolic process response to toxic substance xenobiotic metabolic process | cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle | arachidonic acid epoxygenase activity aromatase activity heme binding iron ion binding monooxygenase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen oxygen binding | Homo sapiens | Alternative splicing Endoplasmic reticulum Heme Iron Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Reference proteome | MDSISTAILL | MDSISTAILLLLLALVCLLLTLSSRDKGKLPPGPRPLSILGNLLLLCSQDMLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILRNFGMGKRSIEERILEEGSFLLAELRKTEGEPFDPTFVLSRSVSNIICSVLFGSRFDYDDERLLTIIRLINDNFQIMSSPWGELYDIFPSLLDWVPGPHQRIFQNFKCLRDLIAHSVHDHQASLDPRSPRDFIQCFLTKMAEEKEDPLSHFHMDTLLMTTHNLLFGGTKTVSTTLHHAFLALMKYPKV... | epoxygenase P450 pathway naphthalene catabolic process response to toxic substance xenobiotic metabolic process cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle arachidonic acid epoxygenase activity aromatase activity heme binding iron ion binding monooxygenase activity oxidoreductase... |
intracellular transport of viral protein in host cell suppression by virus of host gene expression suppression by virus of host translation initiation viral translational shunt | host cell cytoplasm | RNA binding | Human adenovirus C serotype 2 | Chaperone Eukaryotic host gene expression shutoff by virus Eukaryotic host translation shutoff by virus Host cytoplasm Host gene expression shutoff by virus Host-virus interaction Inhibition of eukaryotic host translation factors by virus Late protein Methylation Phosphoprotein Reference proteome RNA-binding Translatio... | MESVEKEDSL | MESVEKEDSLTAPFEFATTASTDAANAPTTFPVEAPPLEEEEVIIEQDPGFVSEDDEDRSVPTEDKKQDQDDAEANEEQVGRGDQRHGDYLDVGDDVLLKHLQRQCAIICDALQERSDVPLAIADVSLAYERHLFSPRVPPKRQENGTCEPNPRLNFYPVFAVPEVLATYHIFFQNCKIPLSCRANRSRADKQLALRQGAVIPDIASLDEVPKIFEGLGRDEKRAANALQQENSENESHCGVLVELEGDNARLAVLKRSIEVTHFAYPALNLPPKVMSTVMSELIVRRARPLERDANLQEQTEEGLPAVGDEQLARWLET... | intracellular transport of viral protein in host cell suppression by virus of host gene expression suppression by virus of host translation initiation viral translational shunt host cell cytoplasm RNA binding Human adenovirus C serotype 2 Chaperone Eukaryotic host gene expression shutoff by virus Eukaryotic host trans... |
auditory behavior cell morphogenesis involved in neuron differentiation cellular response to cocaine chloride transmembrane transport cranial nerve development D-aspartate import across plasma membrane gamma-aminobutyric acid biosynthetic process intracellular sodium ion homeostasis L-aspartate import across plasma mem... | basal plasma membrane; basolateral plasma membrane; cell periphery; cell projection; cell surface; dendritic spine; membrane protein complex; mitochondrial inner membrane; neuron projection; neuronal cell body; plasma membrane; synapse | acidic amino acid transmembrane transporter activity amino acid binding glutamate binding glutamate:sodium symporter activity high-affinity L-glutamate transmembrane transporter activity L-glutamate transmembrane transporter activity metal ion binding neutral L-amino acid transmembrane transporter activity | Rattus norvegicus | Alternative splicing Amino-acid transport Cell membrane Chloride Direct protein sequencing Glycoprotein Membrane Metal-binding Phosphoprotein Potassium Reference proteome Sodium Symport Transmembrane Transmembrane helix Transport | MTKSNGEEPR | MTKSNGEEPRMGSRMERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVSAVIVGTILGFALRPYKMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMGMRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMYREGKIVQVTAADAFLDLIRNMFPPNLVEACFKQFKTSYEKRSFKVPIQANETLLGAVINNVSEAMETLTRIREEMVPVPGSVNGVNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPLGILFLIAGKILEMEDMGVIGGQLAMYTVT... | auditory behavior cell morphogenesis involved in neuron differentiation cellular response to cocaine chloride transmembrane transport cranial nerve development D-aspartate import across plasma membrane gamma-aminobutyric acid biosynthetic process intracellular sodium ion homeostasis L-aspartate import across plasma mem... |
denitrification pathway nitrate assimilation | periplasmic space | copper ion binding nitrite reductase (NO-forming) activity | Achromobacter cycloclastes | 3D-structure Copper Direct protein sequencing FAD Flavoprotein Metal-binding Nitrate assimilation Oxidoreductase Periplasm Repeat Signal | MTEQLQMTRR | MTEQLQMTRRTMLAGAALAGAVAPLLHTAQAHAAGAAAAAGAAPVDISTLPRVKVDLVKPPFVHAHDQVAKTGPRVVEFTMTIEEKKLVIDREGTEIHAMTFNGSVPGPLMVVHENDYVELRLINPDTNTLLHNIDFHAATGALGGGALTQVNPGEETTLRFKATKPGVFVYHCAPEGMVPWHVTSGMNGAIMVLPRDGLKDEKGQPLTYDKIYYVGEQDFYVPKDEAGNYKKYETPGEAYEDAVKAMRTLTPTHIVFNGAVGALTGDHALTAAVGERVLVVHSQANRDTRPHLIGGHGDYVWATGKFRNPPDLDQETWL... | denitrification pathway nitrate assimilation periplasmic space copper ion binding nitrite reductase (NO-forming) activity Achromobacter cycloclastes3D-structure Copper Direct protein sequencing FAD Flavoprotein Metal-binding Nitrate assimilation Oxidoreductase Periplasm Repeat Signal MTEQLQMTRR MTEQLQMTRRTMLAGAALAGAVAP... |
protein folding response to oxidative stress | cytoplasm; cytosol; intracellular membrane-bounded organelle; mitochondrion; nucleus | cyclosporin A binding peptidyl-prolyl cis-trans isomerase activity | Drosophila melanogaster | Cytoplasm Direct protein sequencing Isomerase Phosphoprotein Reference proteome Rotamase | MVSFCATLIR | MVSFCATLIRQFRHRSAAAFQIAESAILANKSITLASSACSVNRGQLQFGIQIVREYSKASKMSTLPRVFFDMTADNEPLGRIVMELRSDVVPKTAENFRALCTGEKGFGYKGSIFHRVIPNFMCQGGDFTNHNGTGGKSIYGNKFPDENFELKHTGSGILSMANAGANTNGSQFFICTVKTAWLDNKHVVFGEVVEGLDVVKKIESYGSQSGKTSKKIIVANSGSL | protein folding response to oxidative stress cytoplasm; cytosol; intracellular membrane-bounded organelle; mitochondrion; nucleus cyclosporin A binding peptidyl-prolyl cis-trans isomerase activity Drosophila melanogaster Cytoplasm Direct protein sequencing Isomerase Phosphoprotein Reference proteome Rotamase MVSFCATLIR... |
chaeta development imaginal disc-derived leg segmentation positive regulation of autophagy positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II sex comb development snRNA 3'-end processing | CKM complex; mediator complex; nucleus | cyclin-dependent protein serine/threonine kinase regulator activity transcription coregulator activity | Drosophila melanogaster | Cyclin Developmental protein Nucleus Reference proteome Repressor Transcription Transcription regulation | MAGNFWQSSH | MAGNFWQSSHSQQWILDKPDLLRERQHDLLALNEDEYQKVFIFFANVIQVLGEQLKLRQQVIATATVYFKRFYARNSLKNIDPLLLAPTCILLASKVEEFGVISNSRLISICQSAIKTKFSYAYAQEFPYRTNHILECEFYLLENLDCCLIVYQPYRPLLQLVQDMGQEDQLLTLSWRIVNDSLRTDVCLLYPPYQIAIACLQIACVILQKDATKQWFAELNVDLDKVQEIVRAIVNLYELWKDWKEKDEIQMLLSKIPKPKPPPQR | chaeta development imaginal disc-derived leg segmentation positive regulation of autophagy positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II sex comb development snRNA 3'-end processing CKM complex; mediator complex; nucleus cyclin-dependent protein serine/threon... |
chemical synaptic transmission G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger gastric acid secretion immune response positive regulation of vasoconstriction | dendrite; plasma membrane; synapse | G protein-coupled serotonin receptor activity histamine receptor activity neurotransmitter receptor activity | Homo sapiens | 3D-structure Alternative splicing Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MAPNGTASSF | MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCCRLANRNSHKTSLRSN... | chemical synaptic transmission G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger gastric acid secretion immune response positive regulation of vasoconstriction dendrite; plasma membrane; synapse G protein-coupled serotonin receptor activity histamine receptor activity neurotran... |
acute inflammatory response to antigenic stimulus arachidonic acid secretion cellular response to hypoxia G protein-coupled receptor signaling pathway intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator maintenance of blood-brain barrier negative regulation of blood pressure negati... | endosome; plasma membrane | beta-2 adrenergic receptor binding bradykinin receptor activity protease binding protein heterodimerization activity type 1 angiotensin receptor binding | Rattus norvegicus | Alternative splicing Cell membrane Direct protein sequencing Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MDTRSSLCPK | MDTRSSLCPKTQAVVAVFWGPGCHLSTCIEMFNITTQALGSAHNGTFSEVNCPDTEWWSWLNAIQAPFLWVLFLLAALENIFVLSVFCLHKTNCTVAEIYLGNLAAADLILACGLPFWAITIANNFDWLFGEVLCRVVNTMIYMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWSCTLLLSSPMLVFRTMKDYREEGHNVTACVIVYPSRSWEVFTNMLLNLVGFLLPLSIITFCTVRIMQVLRNNEMKKFKEVQTEKKATVLVLAVLGLFVLCWFPFQISTFLDTLLRLGVLSGCWNERAVDIVTQ... | acute inflammatory response to antigenic stimulus arachidonic acid secretion cellular response to hypoxia G protein-coupled receptor signaling pathway intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator maintenance of blood-brain barrier negative regulation of blood pressure negati... |
calcium-mediated signaling cell surface receptor signaling pathway dendritic cell chemotaxis G protein-coupled receptor signaling pathway immune response neutrophil chemotaxis positive regulation of cytosolic calcium ion concentration receptor internalization | external side of plasma membrane; plasma membrane; secretory granule membrane | C-C chemokine binding C-C chemokine receptor activity chemokine receptor activity G protein-coupled receptor activity interleukin-8 binding interleukin-8 receptor activity | Homo sapiens | 3D-structure Cell membrane Chemotaxis Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MSNITDPQMW | MSNITDPQMWDFDDLNFTGMPPADEDYSPCMLETETLNKYVVIIAYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRHLVKFVCLGCWGLSMNLSLPFFLFRQAYHPNNSSPVCYEVLGNDTAKWRMVLRILPHTFGFIVPLFVMLFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQESCERRNNIGRALDATEILGFLHSCLNPIIYAFIGQNFRHGFLKIL... | calcium-mediated signaling cell surface receptor signaling pathway dendritic cell chemotaxis G protein-coupled receptor signaling pathway immune response neutrophil chemotaxis positive regulation of cytosolic calcium ion concentration receptor internalization external side of plasma membrane; plasma membrane; secretory... |
acute inflammatory response to antigenic stimulus calcium-mediated signaling cell surface receptor signaling pathway cellular defense response chemotaxis dendritic cell chemotaxis immune response inflammatory response interleukin-8-mediated signaling pathway metanephric tubule morphogenesis midbrain development negativ... | cell surface; external side of plasma membrane; mast cell granule; membrane; microtubule cytoskeleton; mitotic spindle; nucleoplasm; plasma membrane; secretory granule membrane | C-C chemokine binding C-C chemokine receptor activity C-X-C chemokine receptor activity G protein-coupled receptor activity interleukin-8 binding interleukin-8 receptor activity | Homo sapiens | 3D-structure Cell membrane Chemotaxis Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MEDFNMESDS | MEDFNMESDSFEDFWKGEDLSNYSYSSTLPPFLLDAAPCEPESLEINKYFVVIIYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRYLVKFICLSIWGLSLLLALPVLLFRRTVYSSNVSPACYEDMGNNTANWRMLLRILPQSFGFIVPLLIMLFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQETCERRNHIDRALDATEILGILHSCLNPLIYAFIGQK... | acute inflammatory response to antigenic stimulus calcium-mediated signaling cell surface receptor signaling pathway cellular defense response chemotaxis dendritic cell chemotaxis immune response inflammatory response interleukin-8-mediated signaling pathway metanephric tubule morphogenesis midbrain development negativ... |
acute-phase response antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to L-arginine cellular response to tumor necrosis factor cellular response to xenobiotic stimulus defense response to Gram-negative bacterium defense response to Gram-positive bacterium disruption of cell wall... | apical part of cell; extracellular space; protein-containing complex; zymogen granule | growth factor binding hormone activity identical protein binding metal ion binding oligosaccharide binding peptidoglycan binding signaling receptor activity | Rattus norvegicus | Acute phase Antimicrobial Direct protein sequencing Disulfide bond Inflammatory response Lectin Metal-binding Reference proteome Secreted Signal Zinc | MLHRLAFPVM | MLHRLAFPVMSWMLLSCLMLLSQVQGEDSPKKIPSARISCPKGSQAYGSYCYALFQIPQTWFDAELACQKRPEGHLVSVLNVAEASFLASMVKNTGNSYQYTWIGLHDPTLGGEPNGGGWEWSNNDIMNYVNWERNPSTALDRGFCGSLSRSSGFLRWRDTTCEVKLPYVCKFTG | acute-phase response antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to L-arginine cellular response to tumor necrosis factor cellular response to xenobiotic stimulus defense response to Gram-negative bacterium defense response to Gram-positive bacterium disruption of cell wall... |
anatomical structure morphogenesis cell differentiation cellular response to osmotic stress negative regulation of transcription by RNA polymerase II | chromatin; nucleus | cis-regulatory region sequence-specific DNA binding DNA binding, bending DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding tran... | Saccharomyces cerevisiae | DNA-binding Nucleus Reference proteome Repressor Transcription Transcription regulation | MNPKSSTPKI | MNPKSSTPKIPRPKNAFILFRQHYHRILIDEWTAQGVEIPHNSNISKIIGTKWKGLQPEDKAHWENLAEKEKLEHERKYPEYKYKPVRKSKKKQLLLKEIEQQQQQQQKEQQQQKQSQPQLQQPFNNNIVLMKRAHSLSPSSSVSSSNSYQFQLNNDLKRLPIPSVNTSNYMVSRSLSGLPLTHDKTARDLPQLSSQLNSIPYYSAPHDPSTRHHYLNVAQAQPRANSTPQLPFISSIINNSSQTPVTTTTTSTTTATSSPGKFSSSPNSSVLENNRLNSINNSNQYLPPPLLPSLQDFQLDQYQQLKQMGPTYIVKPLS... | anatomical structure morphogenesis cell differentiation cellular response to osmotic stress negative regulation of transcription by RNA polymerase II chromatin; nucleus cis-regulatory region sequence-specific DNA binding DNA binding, bending DNA-binding transcription factor activity, RNA polymerase II-specific DNA-bind... |
proteasomal protein catabolic process proteasomal ubiquitin-independent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process | cytosol; nucleus; proteasome complex; proteasome core complex, beta-subunit complex; proteasome storage granule | endopeptidase activity threonine-type endopeptidase activity | Saccharomyces cerevisiae | 3D-structure Cytoplasm Hydrolase Nucleus Protease Proteasome Reference proteome Threonine protease Zymogen | MAGLSFDNYQ | MAGLSFDNYQRNNFLAENSHTQPKATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNICDIQEEQVDITA | proteasomal protein catabolic process proteasomal ubiquitin-independent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process cytosol; nucleus; proteasome complex; proteasome core complex, beta-subunit complex; proteasome storage granule endopeptidase activity threonine-type endope... |
dephosphorylation invasive growth in response to glucose limitation pseudohyphal growth | cytoplasm; mitochondrion | protein tyrosine phosphatase activity | Saccharomyces cerevisiae | Cytoplasm Hydrolase Phosphoprotein Protein phosphatase Reference proteome | MAAAPWYIRQ | MAAAPWYIRQRDTDLLGKFKFIQNQEDGRLREATNGTVNSRWSLGVSIEPRNDARNRYVNIMPYERNRVHLKTLSGNDYINASYVKVNVPGQSIEPGYYIATQGPTRKTWDQFWQMCYHNCPLDNIVIVMVTPLVEYNREKCYQYWPRGGVDDTVRIASKWESPGGANDMTQFPSDLKIEFVNVHKVKDYYTVTDIKLTPTDPLVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLNSRGNPIIVHCSAGVGRTGTFIALDHLMHDTLDFKNITERSRHSDRATEEYTRDLIEQIVLQLRSQRMKMVQTKDQFLF... | dephosphorylation invasive growth in response to glucose limitation pseudohyphal growth cytoplasm; mitochondrion protein tyrosine phosphatase activity Saccharomyces cerevisiae Cytoplasm Hydrolase Phosphoprotein Protein phosphatase Reference proteome MAAAPWYIRQ MAAAPWYIRQRDTDLLGKFKFIQNQEDGRLREATNGTVNSRWSLGVSIEPRNDARNRY... |
ceramide biosynthetic process intracellular sphingolipid homeostasis sphingosine biosynthetic process | endoplasmic reticulum; endoplasmic reticulum membrane; SPOTS complex | pyridoxal phosphate binding serine C-palmitoyltransferase activity | Saccharomyces cerevisiae | 3D-structure Acyltransferase Cytoplasm Endoplasmic reticulum Lipid metabolism Membrane Phosphoprotein Pyridoxal phosphate Reference proteome Sphingolipid metabolism Transferase Transmembrane Transmembrane helix | MAHIPEVLPK | MAHIPEVLPKSIPIPAFIVTTSSYLWYYFNLVLTQIPGGQFIVSYIKKSHHDDPYRTTVEIGLILYGIIYYLSKPQQKKSLQAQKPNLSPQEIDALIEDWEPEPLVDPSATDEQSWRVAKTPVTMEMPIQNHITITRNNLQEKYTNVFNLASNNFLQLSATEPVKEVVKTTIKNYGVGACGPAGFYGNQDVHYTLEYDLAQFFGTQGSVLYGQDFCAAPSVLPAFTKRGDVIVADDQVSLPVQNALQLSRSTVYYFNHNDMNSLECLLNELTEQEKLEKLPAIPRKFIVTEGIFHNSGDLAPLPELTKLKNKYKFRLFVD... | ceramide biosynthetic process intracellular sphingolipid homeostasis sphingosine biosynthetic process endoplasmic reticulum; endoplasmic reticulum membrane; SPOTS complex pyridoxal phosphate binding serine C-palmitoyltransferase activity Saccharomyces cerevisiae 3D-structure Acyltransferase Cytoplasm Endoplasmic retic... |
negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription elongation by RNA polymerase II positive regulation of transcription initiation by RNA polymerase II regulation of transcription by RNA polymerase II RNA polymerase II... | core mediator complex; mediator complex; nucleus | transcription coactivator activity transcription coregulator activity | Saccharomyces cerevisiae | 3D-structure Activator Direct protein sequencing Nucleus Reference proteome Transcription Transcription regulation | MASRVDETTV | MASRVDETTVPSYYYYVDPETTYTYQQPNPLQDLISVYGLDDISRQVARTNLDGTKAVKLRKSYKNQIADLSGKFSTIPTRENGKGGQIAHILFQNNPDMMIQPPQQGQNMSEQQWREQLRNRDIALFQPPNFDWDLCSSVLSQFERSYPSEFANQNQGGAQAPFDIDDLAFDLDGTGKSQSGSNSGNNSKKRKNKSSGSSMATPTHSDSHEDMKRRRLE | negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription elongation by RNA polymerase II positive regulation of transcription initiation by RNA polymerase II regulation of transcription by RNA polymerase II RNA polymerase II... |
cell wall organization peptidoglycan biosynthetic process regulation of cell shape response to antibiotic | cytoplasm; plasma membrane | ATP binding D-alanine-D-alanine ligase activity metal ion binding | Enterococcus faecium | 3D-structure Antibiotic resistance ATP-binding Cell membrane Cell shape Cell wall biogenesis/degradation Direct protein sequencing Ligase Magnesium Manganese Membrane Metal-binding Nucleotide-binding Peptidoglycan synthesis Plasmid | MNRIKVAILF | MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGITKSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKSGEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPVAATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCAVLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETAKKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPR... | cell wall organization peptidoglycan biosynthetic process regulation of cell shape response to antibiotic cytoplasm; plasma membrane ATP binding D-alanine-D-alanine ligase activity metal ion binding Enterococcus faecium 3D-structure Antibiotic resistance ATP-binding Cell membrane Cell shape Cell wall biogenesis/degrada... |
thiamine biosynthetic process thiamine diphosphate biosynthetic process | cytosol | thiaminase activity | Bacillus subtilis | 3D-structure Hydrolase Reference proteome Thiamine biosynthesis | MKFSEECRSA | MKFSEECRSAAAEWWEGSFVHPFVQGIGDGTLPIDRFKYYVLQDSYYLTHFAKVQSFGAAYAKDLYTTGRMASHAQGTYEAEMALHREFAELLEISEEERKAFKPSPTAYSYTSHMYRSVLSGNFAEILAALLPCYWLYYEVGEKLLHCDPGHPIYQKWIGTYGGDWFRQQVEEQINRFDELAENSTEEVRAKMKENFVISSYYEYQFWGMAYRKEGWSDSAIKEVEECGASRHNG | thiamine biosynthetic process thiamine diphosphate biosynthetic process cytosol thiaminase activity Bacillus subtilis 3D-structure Hydrolase Reference proteome Thiamine biosynthesis MKFSEECRSA MKFSEECRSAAAEWWEGSFVHPFVQGIGDGTLPIDRFKYYVLQDSYYLTHFAKVQSFGAAYAKDLYTTGRMASHAQGTYEAEMALHREFAELLEISEEERKAFKPSPTAYSYTSHMYRSVLSGNFAE... |
thiamine biosynthetic process thiamine diphosphate biosynthetic process | cytoplasm | isomerase activity thiamine-phosphate diphosphorylase activity | Bacillus subtilis | 3D-structure Isomerase Reference proteome Thiamine biosynthesis | MELHAITDDS | MELHAITDDSKPVEELARIIITIQNEVDFIHIRERSKSAADILKLLDLIFEGGIDKRKLVMNGRVDIALFSTIHRVQLPSGSFSPKQIRARFPHLHIGRSVHSLEEAVQAEKEDADYVLFGHVFETDCKKGLEGRGVSLLSDIKQRISIPVIAIGGMTPDRLRDVKQAGADGIAVMSGIFSSAEPLEAARRYSRKLKEMRYEKAL | thiamine biosynthetic process thiamine diphosphate biosynthetic process cytoplasm isomerase activity thiamine-phosphate diphosphorylase activity Bacillus subtilis 3D-structure Isomerase Reference proteome Thiamine biosynthesis MELHAITDDS MELHAITDDSKPVEELARIIITIQNEVDFIHIRERSKSAADILKLLDLIFEGGIDKRKLVMNGRVDIALFSTIHRVQLPSGS... |
viral budding via host ESCRT complex | viral nucleocapsid | nucleic acid binding structural constituent of virion zinc ion binding | Bovine leukemia virus | Capsid protein Host-virus interaction Lipoprotein Metal-binding Myristate Phosphoprotein Repeat Ribosomal frameshifting Viral budding Viral budding via the host ESCRT complexes Viral matrix protein Viral nucleoprotein Viral release from host cell Virion Zinc Zinc-finger | MGNSPSYNPP | MGNSPSYNPPAGISPSDWLNLLQSAQRLNPRPSPSDFTDLKNYIHWFHKTQKKPWTFTSGGPASCPPGKFGRVPLVLATLNEVLSNDEGAPGASAPEEQPPPYDPPAVLPIISEGNRNRHRAWALRELQDIKKEIENKAPGSQVWIQTLRLAILQADPTPADLEQLCQYIASPVDQTAHMTSLTAAIAAEAANTLQGFNPKMGTLTQQSAQPNAGDLRSQYQNLWLQAWKNLPTRPSVQPWSTIVQGPAESYVEFVNRLQISLADNLPDGVPKEPIIDSLSYANANKECQQILQGRGLVAAPVGQKLQACAHWAPKTKQP... | viral budding via host ESCRT complex viral nucleocapsid nucleic acid binding structural constituent of virion zinc ion binding Bovine leukemia virus Capsid protein Host-virus interaction Lipoprotein Metal-binding Myristate Phosphoprotein Repeat Ribosomal frameshifting Viral budding Viral budding via the host ESCRT com... |
B cell receptor transport into membrane raft cell activation cell migration cell-cell adhesion chemokine receptor transport out of membrane raft cholesterol homeostasis glomerular parietal epithelial cell differentiation immune response-regulating cell surface receptor signaling pathway intrinsic apoptotic signaling pa... | cell surface; intracellular membrane-bounded organelle; membrane; membrane raft; plasma membrane; side of membrane | protein kinase binding protein tyrosine kinase activator activity | Homo sapiens | Alternative splicing Cell membrane Glycoprotein GPI-anchor Lipoprotein Membrane Reference proteome Signal | MGRAMVARLG | MGRAMVARLGLGLLLLALLLPTQIYSSETTTGTSSNSSQSTSNSGLAPNPTNATTKAAGGALQSTASLFVVSLSLLHLYS | B cell receptor transport into membrane raft cell activation cell migration cell-cell adhesion chemokine receptor transport out of membrane raft cholesterol homeostasis glomerular parietal epithelial cell differentiation immune response-regulating cell surface receptor signaling pathway intrinsic apoptotic signaling pa... |
angiogenesis camera-type eye morphogenesis cell-cell adhesion endothelial cell proliferation extracellular matrix organization | basement membrane; collagen trimer; collagen-containing extracellular matrix; endoplasmic reticulum lumen; extracellular matrix; extracellular region; extracellular space | extracellular matrix structural constituent extracellular matrix structural constituent conferring tensile strength protein-macromolecule adaptor activity | Homo sapiens | Angiogenesis Basement membrane Cell adhesion Collagen Corneal dystrophy Disease variant Extracellular matrix Hydroxylation Reference proteome Repeat Secreted Signal | MLGTLTPLSS | MLGTLTPLSSLLLLLLVLVLGCGPRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGL... | angiogenesis camera-type eye morphogenesis cell-cell adhesion endothelial cell proliferation extracellular matrix organization basement membrane; collagen trimer; collagen-containing extracellular matrix; endoplasmic reticulum lumen; extracellular matrix; extracellular region; extracellular space extracellular matrix s... |
cellular response to hypoxia response to absence of light response to mechanical stimulus thigmotropism | cytosol; plant-type vacuole; plasmodesma | calcium ion binding mRNA binding | Arabidopsis thaliana | Alternative splicing Calcium Metal-binding Reference proteome Repeat | MADKLTDDQI | MADKLTDDQITEYRESFRLFDKNGDGSITKKELGTMMRSIGEKPTKADLQDLMNEADLDGDGTIDFPEFLCVMAKNQGHDQAPRHTKKTMADKLTDDQITEYRESFRLFDKNGDGSITKKELRTVMFSLGKNRTKADLQDMMNEVDLDGDGTIDFPEFLYLMAKNQGHDQAPRHTKKTMVDYQLTDDQILEFREAFRVFDKNGDGYITVNELRTTMRSLGETQTKAELQDMINEADADGDGTISFSEFVCVMTGKMIDTQSKKETYRVVNQGQGQVQRHTRNDRAGGTNWERDIAVGVASNIIASPISDFMKDRFKDLFE... | cellular response to hypoxia response to absence of light response to mechanical stimulus thigmotropism cytosol; plant-type vacuole; plasmodesma calcium ion binding mRNA binding Arabidopsis thaliana Alternative splicing Calcium Metal-binding Reference proteome Repeat MADKLTDDQI MADKLTDDQITEYRESFRLFDKNGDGSITKKELGTMMRSIG... |
photorespiration reductive pentose-phosphate cycle | chloroplast | magnesium ion binding monooxygenase activity ribulose-bisphosphate carboxylase activity | Solanum tuberosum | Acetylation Calvin cycle Carbon dioxide fixation Chloroplast Direct protein sequencing Disulfide bond Lyase Magnesium Metal-binding Methylation Monooxygenase Oxidoreductase Photorespiration Photosynthesis Plastid Reference proteome | MSPQTETKAS | MSPQTETKASVGFKAGVKEYKLTYYTPEYQTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYRIERVVGEKDQYIAYVAYPLDLFEEGSVTNMLTSIVGNVFGFKALRALRLEDLRIPVAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALFKAQAETGEIKGHYLNATAGTCEEMMKRAVFARELGTPIVMHDYLTGGFTANTTLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRM... | photorespiration reductive pentose-phosphate cycle chloroplast magnesium ion binding monooxygenase activity ribulose-bisphosphate carboxylase activity Solanum tuberosum Acetylation Calvin cycle Carbon dioxide fixation Chloroplast Direct protein sequencing Disulfide bond Lyase Magnesium Metal-binding Methylation Monooxy... |
histidine catabolic process to glutamate and formamide histidine catabolic process to glutamate and formate | cytoplasm | urocanate hydratase activity | Pseudomonas putida | 3D-structure Cytoplasm Direct protein sequencing Histidine metabolism Lyase NAD | MTDNNKYRDV | MTDNNKYRDVEIRAPRGNKLTAKSWLTEAPLRMLMNNLDPQVAENPKELVVYGGIGRAARNWECYDKIVETLTRLEDDETLLVQSGKPVGVFKTHSNAPRVLIANSNLVPHWANWEHFNELDAKGLAMYGQMTAGSWIYIGSQGIVQGTYETFVEAGRQHYGGTVKAKWVLTAGLGGMGGAQPLAATLAGACSLNIECQQSRIDFRLETRYVDEQATDLDDALVRIAKYTAEGKAISIALHGNAAEILPELVKRGVRPDMVTDQTSAHDPLNGYLPAGWTWEQYRDRAQTEPAAVVKAAKQSMAVHVQAMLDFQKQGVPT... | histidine catabolic process to glutamate and formamide histidine catabolic process to glutamate and formate cytoplasm urocanate hydratase activity Pseudomonas putida 3D-structure Cytoplasm Direct protein sequencing Histidine metabolism Lyase NAD MTDNNKYRDV MTDNNKYRDVEIRAPRGNKLTAKSWLTEAPLRMLMNNLDPQVAENPKELVVYGGIGRAARNWE... |
positive regulation of DNA-templated transcription positive regulation of elastin biosynthetic process quorum sensing regulation of DNA-templated transcription regulation of elastin catabolic process regulation of gene expression | protein-DNA complex | DNA-binding transcription activator activity DNA-binding transcription factor activity sequence-specific DNA binding transcription cis-regulatory region binding | Pseudomonas aeruginosa | 3D-structure Activator DNA-binding Quorum sensing Reference proteome Transcription Transcription regulation | MALVDGFLEL | MALVDGFLELERSSGKLEWSAILQKMASDLGFSKILFGLLPKDSQDYENAFIVGNYPAAWREHYDRAGYARVDPTVSHCTQSVLPIFWEPSIYQTRKQHEFFEEASAAGLVYGLTMPLHGARGELGALSLSVEAENRAEANRFMESVLPTLWMLKDYALQSGAGLAFEHPVSKPVVLTSREKEVLQWCAIGKTSWEISVICNCSEANVNFHMGNIRRKFGVTSRRVAAIMAVNLGLITL | positive regulation of DNA-templated transcription positive regulation of elastin biosynthetic process quorum sensing regulation of DNA-templated transcription regulation of elastin catabolic process regulation of gene expression protein-DNA complex DNA-binding transcription activator activity DNA-binding transcription... |
acute-phase response fever generation inflammatory response to antigenic stimulus insulin secretion lipid metabolic process memory negative regulation of apoptotic process negative regulation of cell migration negative regulation of glutamate secretion negative regulation of heterotypic cell-cell adhesion negative regu... | centrosome; cytosol; extracellular region; extracellular space; nucleoplasm; vesicle | cytokine activity interleukin-1 receptor antagonist activity interleukin-1 receptor binding interleukin-1 type I receptor antagonist activity interleukin-1 type II receptor antagonist activity interleukin-1, type I receptor binding interleukin-1, type II receptor binding | Mus musculus | Alternative splicing Cytoplasm Disulfide bond Glycoprotein Reference proteome Secreted Signal | MEICWGPYSH | MEICWGPYSHLISLLLILLFHSEAACRPSGKRPCKMQAFRIWDTNQKTFYLRNNQLIAGYLQGPNIKLEEKIDMVPIDLHSVFLGIHGGKLCLSCAKSGDDIKLQLEEVNITDLSKNKEEDKRFTFIRSEKGPTTSFESAACPGWFLCTTLEADRPVSLTNTPEEPLIVTKFYFQEDQ | acute-phase response fever generation inflammatory response to antigenic stimulus insulin secretion lipid metabolic process memory negative regulation of apoptotic process negative regulation of cell migration negative regulation of glutamate secretion negative regulation of heterotypic cell-cell adhesion negative regu... |
carboxylic acid metabolic process cellular response to norepinephrine stimulus chronic inflammatory response to antigenic stimulus female pregnancy fever generation inflammatory response to antigenic stimulus insulin secretion lipid metabolic process memory negative regulation of apoptotic process negative regulation o... | extracellular region; extracellular space; vesicle | cytokine activity interleukin-1 receptor antagonist activity interleukin-1 receptor binding interleukin-1 type I receptor antagonist activity interleukin-1 type II receptor antagonist activity interleukin-1, type I receptor binding interleukin-1, type II receptor binding | Rattus norvegicus | Disulfide bond Glycoprotein Reference proteome Secreted Signal | MEICRGPYSH | MEICRGPYSHLISLLLILLFRSESAGHPAGKRPCKMQAFRIWDTNQKTFYLRNNQLIAGYLQGPNTKLEEKIDMVPIDFRNVFLGIHGGKLCLSCVKSGDDTKLQLEEVNITDLNKNKEEDKRFTFIRSETGPTTSFESLACPGWFLCTTLEADHPVSLTNTPKEPCTVTKFYFQEDQ | carboxylic acid metabolic process cellular response to norepinephrine stimulus chronic inflammatory response to antigenic stimulus female pregnancy fever generation inflammatory response to antigenic stimulus insulin secretion lipid metabolic process memory negative regulation of apoptotic process negative regulation o... |
ergosterol biosynthetic process methylation | endoplasmic reticulum; lipid droplet; mitochondrial outer membrane; mitochondrion | identical protein binding sterol 24-C-methyltransferase activity | Saccharomyces cerevisiae | Acetylation Endoplasmic reticulum Lipid biosynthesis Lipid metabolism Methyltransferase Microsome Mitochondrion Phosphoprotein Reference proteome S-adenosyl-L-methionine Steroid biosynthesis Steroid metabolism Sterol biosynthesis Sterol metabolism Transferase | MSETELRKRQ | MSETELRKRQAQFTRELHGDDIGKKTGLSALMSKNNSAQKEAVQKYLRNWDGRTDKDAEERRLEDYNEATHSYYNVVTDFYEYGWGSSFHFSRFYKGESFAASIARHEHYLAYKAGIQRGDLVLDVGCGVGGPAREIARFTGCNVIGLNNNDYQIAKAKYYAKKYNLSDQMDFVKGDFMKMDFEENTFDKVYAIEATCHAPKLEGVYSEIYKVLKPGGTFAVYEWVMTDKYDENNPEHRKIAYEIELGDGIPKMFHVDVARKALKNCGFEVLVSEDLADNDDEIPWYYPLTGEWKYVQNLANLATFFRTSYLGRQFTTAM... | ergosterol biosynthetic process methylation endoplasmic reticulum; lipid droplet; mitochondrial outer membrane; mitochondrion identical protein binding sterol 24-C-methyltransferase activity Saccharomyces cerevisiae Acetylation Endoplasmic reticulum Lipid biosynthesis Lipid metabolism Methyltransferase Microsome Mitoc... |
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway astrocyte activation calcium-mediated signaling cell adhesion cell surface receptor signaling pathway cellular response to amyloid-beta chemotaxis complement receptor mediated signaling pathway defense response to bacterium G protein-coupled rece... | cytoplasm; ficolin-1-rich granule membrane; membrane; plasma membrane; specific granule membrane; tertiary granule membrane | amyloid-beta binding cargo receptor activity complement receptor activity G protein-coupled receptor activity N-formyl peptide receptor activity scavenger receptor binding signaling receptor activity | Homo sapiens | 3D-structure Cell membrane Chemotaxis Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Transducer Transmembrane Transmembrane helix | METNFSTPLN | METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTS... | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway astrocyte activation calcium-mediated signaling cell adhesion cell surface receptor signaling pathway cellular response to amyloid-beta chemotaxis complement receptor mediated signaling pathway defense response to bacterium G protein-coupled rece... |
cardiac muscle contraction desensitization of G protein-coupled receptor signaling pathway G protein-coupled acetylcholine receptor signaling pathway G protein-coupled receptor signaling pathway heart development negative regulation of relaxation of smooth muscle negative regulation of striated muscle contraction negat... | cilium; cytoplasm; cytosol; membrane; plasma membrane; postsynapse; presynapse | alpha-2A adrenergic receptor binding ATP binding beta-adrenergic receptor kinase activity Edg-2 lysophosphatidic acid receptor binding G protein-coupled receptor binding G protein-coupled receptor kinase activity protein kinase activity | Homo sapiens | 3D-structure ATP-binding Cell membrane Cell projection Cytoplasm Kinase Membrane Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Synapse Transferase | MADLEAVLAD | MADLEAVLADVSYLMAMEKSKATPAARASKKILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKELLACSHPFSKSATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKP... | cardiac muscle contraction desensitization of G protein-coupled receptor signaling pathway G protein-coupled acetylcholine receptor signaling pathway G protein-coupled receptor signaling pathway heart development negative regulation of relaxation of smooth muscle negative regulation of striated muscle contraction negat... |
adenylate cyclase-activating adrenergic receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway cell-cell signaling G protein-coupled receptor signaling pathway neuron-glial cell signaling phospholipase C-activating G protein-coupled receptor signaling pathway positive regul... | plasma membrane | alpha1-adrenergic receptor activity identical protein binding | Homo sapiens | Cell membrane G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MTFRDLLSVS | MTFRDLLSVSFEGPRPDSSAGGSSAGGGGGSAGGAAPSEGPAVGGVPGGAGGGGGVVGAGSGEDNRSSAGEPGSAGAGGDVNGTAAVGGLVVSAQGVGVGVFLAAFILMAVAGNLLVILSVACNRHLQTVTNYFIVNLAVADLLLSATVLPFSATMEVLGFWAFGRAFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWVVALVVSVGPLLGWKEPVPPDERFCGITEEAGYAVFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGVKRERGKASEVVLRIHCRGAATGADGAHG... | adenylate cyclase-activating adrenergic receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway cell-cell signaling G protein-coupled receptor signaling pathway neuron-glial cell signaling phospholipase C-activating G protein-coupled receptor signaling pathway positive regul... |
cellular response to histamine chemical synaptic transmission digestive tract development epithelial cell morphogenesis G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger gastric acid secretion gastrin-induced gastric acid secretion gland development histamine-induced gastric ac... | dendrite; plasma membrane; synapse | G protein-coupled serotonin receptor activity heterocyclic compound binding histamine receptor activity neurotransmitter receptor activity | Rattus norvegicus | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MEPNGTVHSC | MEPNGTVHSCCLDSMALKVTISVVLTTLILITIAGNVVVCLAVSLNRRLRSLTNCFIVSLAATDLLLGLLVLPFSAIYQLSFTWSFGHVFCNIYTSLDVMLCTASILNLFMISLDRYCAVTDPLRYPVLVTPVRVAISLVFIWVISITLSFLSIHLGWNSRNGTRGGNDTFKCKVQVNEVYGLVDGLVTFYLPLLIMCVTYYRIFKIAREQAKRINHISSWKAATIREHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEAVEGIVLWLGYANSALNPILYAALNRDFRTAYQQLFHCKFASHNSHKTSLRLNN... | cellular response to histamine chemical synaptic transmission digestive tract development epithelial cell morphogenesis G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger gastric acid secretion gastrin-induced gastric acid secretion gland development histamine-induced gastric ac... |
angiogenesis calcium-mediated signaling cell adhesion cell chemotaxis chemokine-mediated signaling pathway immune response negative regulation of cell population proliferation negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage oculomotor nerve development positive regulation of cytos... | cell surface; clathrin-coated pit; early endosome; endosome; external side of plasma membrane; intracellular membrane-bounded organelle; plasma membrane; recycling endosome | C-C chemokine binding C-C chemokine receptor activity C-X-C chemokine binding C-X-C chemokine receptor activity coreceptor activity scavenger receptor activity | Homo sapiens | 3D-structure Cell adhesion Cell membrane Developmental protein Disease variant Disulfide bond Endosome G-protein coupled receptor Glycoprotein Host-virus interaction Membrane Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix Ubl conjugation | MDLHLFDYSE | MDLHLFDYSEPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMIANSVVVWVNIQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVTHLIFSINLFGSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPDTYYLKTVTSASNNETYCRSFYPEHSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLARAISASSDQEKHSSRKIIFSYVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALFTALHVTQCLSLVHCCVNPVLYSFINR... | angiogenesis calcium-mediated signaling cell adhesion cell chemotaxis chemokine-mediated signaling pathway immune response negative regulation of cell population proliferation negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage oculomotor nerve development positive regulation of cytos... |
monoatomic cation transport muscle cell cellular homeostasis musculoskeletal movement neuromuscular junction development neuromuscular process neuromuscular synaptic transmission neuron cellular homeostasis neuronal action potential regulation of membrane potential response to nicotine skeletal muscle contraction skele... | acetylcholine-gated channel complex; cell surface; membrane; neuromuscular junction; neuron projection; plasma membrane; postsynaptic specialization membrane; synapse | acetylcholine binding acetylcholine receptor activity acetylcholine-gated monoatomic cation-selective channel activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | Rattus norvegicus | Cell membrane Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MELTAVLLLL | MELTAVLLLLGLCSAGTVLGSEHETRLVAKLFKDYSSVVRPVGDHREIVQVTVGLQLIQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDVVLYNNADGDFAIVKFTKVLLDYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINPESDQPDLSNFMESGEWVIKEARGWKHWVFYSCCPNTPYLDITYHFVMQRLPLYFIVNVIIPCLLFSFLTSLVFYLPTDSGEKMTLSISVLLSLTVFLLVIVELIPSTSSAVPLIGKYMLFTMVFVIASIIITVIVINTHH... | monoatomic cation transport muscle cell cellular homeostasis musculoskeletal movement neuromuscular junction development neuromuscular process neuromuscular synaptic transmission neuron cellular homeostasis neuronal action potential regulation of membrane potential response to nicotine skeletal muscle contraction skele... |
behavioral response to nicotine monoatomic cation transport muscle cell development muscle contraction nervous system process neuromuscular synaptic transmission postsynaptic membrane organization regulation of membrane potential signal transduction skeletal muscle contraction synaptic transmission, cholinergic | acetylcholine-gated channel complex; neuromuscular junction; neuron projection; plasma membrane; postsynaptic specialization membrane; synapse | acetylcholine binding acetylcholine-gated monoatomic cation-selective channel activity channel activity ligand-gated monoatomic ion channel activity transmembrane signaling receptor activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | Rattus norvegicus | Cell membrane Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Phosphoprotein Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MALGALLLIL | MALGALLLILGILGTPLAPGARGSEAEGQLLKKLFSDYDSSVRPAQEVGDRVGVSIGLTLAQLISLNEKDEEMSTKVYLDLEWTDYRLSWDPAEHDGIESLRVTAESVWLPDVVLLNNNDGNFDVALDINVVVSFEGSVRWQPPGLYRSSCSIQVTYFPFDWQNCTMVFSSYSYDSSEVSLKTGPDPDGQERQEIYIHEGTFIENGQWEIIHKPSRLIHLPGDRRGGKEGHREEVIFYLIIRRKPLFYLVNVIAPCILITLLAIFVFYLPPDAGEKMGLSIFALLTLTVFLLLLADKVPETSLAVPIIIKYLMFTMILVT... | behavioral response to nicotine monoatomic cation transport muscle cell development muscle contraction nervous system process neuromuscular synaptic transmission postsynaptic membrane organization regulation of membrane potential signal transduction skeletal muscle contraction synaptic transmission, cholinergic acetylc... |
monoatomic cation transport musculoskeletal movement regulation of membrane potential skeletal muscle contraction skeletal muscle tissue growth | acetylcholine-gated channel complex; neuromuscular junction; neuron projection; plasma membrane; postsynaptic specialization membrane; synapse | acetylcholine binding acetylcholine-gated monoatomic cation-selective channel activity ligand-gated monoatomic ion channel activity transmembrane signaling receptor activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | Rattus norvegicus | 3D-structure Cell membrane Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Phosphoprotein Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MAGPVPTLGL | MAGPVPTLGLLAALVVCGSWGLNEEQRLIQHLFEEKGYNKELRPVARKEDIVDVALSLTLSNLISLKEVEETLTTNVWIDHAWIDSRLQWNANEFGNITVLRLPSDMVWLPEIVLENNNDGSFQISYACNVLVSDSGHVTWLPPAIFRSSCPISVTYFPFDWQNCSLKFSSLKYTAKEIRLSLKQEEEDNRSYPIEWIIIDPEGFTENGEWEIVHRAAKVNVDPSVPMDSTNHQDVTFYLIIRRKPLFYIINILVPCVLISFMINLVFYLPGDCGEKTSVAISVLLAQSVFLLLISKRLPATSMAIPLVGKFLLFGMVLV... | monoatomic cation transport musculoskeletal movement regulation of membrane potential skeletal muscle contraction skeletal muscle tissue growth acetylcholine-gated channel complex; neuromuscular junction; neuron projection; plasma membrane; postsynaptic specialization membrane; synapse acetylcholine binding acetylcholi... |
fructose 2,6-bisphosphate metabolic process fructose metabolic process | cytosol | 6-phosphofructo-2-kinase activity ATP binding fructose-2,6-bisphosphate 2-phosphatase activity | Rattus norvegicus | 3D-structure ATP-binding Hydrolase Kinase Multifunctional enzyme Nucleotide-binding Phosphoprotein Reference proteome Transferase | MASPRELTQN | MASPRELTQNPLKKIWMPYSNGRPALHASQRGVCMTNCPTLIVMVGLPARGKTYISKKLTRYLNWIGVPTREFNVGQYRRDMVKTYKSFEFFLPDNEEGLKIRKQCALAALNDVRKFLSEEGGHVAVFDATNTTRERRAMIFNFGEQNGYKTFFVESICVDPEVIAANIVQVKLGSPDYVNRDSDEATEDFMRRIECYENSYESLDEEQDRDLSYIKIMDVGQSYVVNRVADHIQSRIVYYLMNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFSKHLAQFISDQNIKDLKVWTSQMKRTIQTAEALSVPYEQ... | fructose 2,6-bisphosphate metabolic process fructose metabolic process cytosol 6-phosphofructo-2-kinase activity ATP binding fructose-2,6-bisphosphate 2-phosphatase activity Rattus norvegicus 3D-structure ATP-binding Hydrolase Kinase Multifunctional enzyme Nucleotide-binding Phosphoprotein Reference proteome Transferas... |
adenylate cyclase-activating adrenergic receptor signaling pathway adenylate cyclase-activating dopamine receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway associative learning cellular response to catecholamine stimulus dopamine receptor signaling pathway long-term syn... | axon; brush border membrane; ciliary membrane; cilium; dendrite; dendritic spine; glutamatergic synapse; neuronal cell body; non-motile cilium; plasma membrane; postsynaptic density membrane | dopamine binding dopamine neurotransmitter receptor activity dopamine neurotransmitter receptor activity, coupled via Gs G protein-coupled receptor activity G-protein alpha-subunit binding | Rattus norvegicus | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MLPPGRNRTA | MLPPGRNRTAQPARLGLQRQLAQVDAPAGSATPLGPAQVVTAGLLTLLIVWTLLGNVLVCAAIVRSRHLRAKMTNIFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGTFCDIWVAFDIMCSTASILNLCIISVDRYWAISRPFRYERKMTQRVALVMVGLAWTLSILISFIPVQLNWHRDKAGSQGQEGLLSNGTPWEEGWELEGRTENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSRGAYEPDPSLRASIKKETKVFKTLSMIMGVFVCCWLPFFILNCMVPFCSSGD... | adenylate cyclase-activating adrenergic receptor signaling pathway adenylate cyclase-activating dopamine receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway associative learning cellular response to catecholamine stimulus dopamine receptor signaling pathway long-term syn... |
activation of phospholipase C activity adenylate cyclase-activating G protein-coupled receptor signaling pathway amylin receptor signaling pathway cell surface receptor signaling pathway negative regulation of ossification ossification osteoclast differentiation positive regulation of calcium-mediated signaling positiv... | acrosomal vesicle; amylin receptor complex 1; amylin receptor complex 2; amylin receptor complex 3; axon; cilium; plasma membrane | amylin receptor activity amyloid-beta binding calcitonin binding calcitonin gene-related peptide receptor activity calcitonin receptor activity | Sus scrofa | Alternative splicing Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Signal Transducer Transmembrane Transmembrane helix | MRFTLTRWCL | MRFTLTRWCLTLFIFLNRPLPVLPDSADGAHTPTLEPEPFLYILGKQRMLEAQHRCYDRMQKLPPYQGEGLYCNRTWDGWSCWDDTPAGVLAEQYCPDYFPDFDAAEKVTKYCGEDGDWYRHPESNISWSNYTMCNAFTPDKLQNAYILYYLAIVGHSLSILTLLISLGIFMFLRYFNLLAPFNALLYPTRSISCQRVTLHKNMFLTYVLNSIIIIVHLVVIVPNGELVKRDPPICKVLHFFHQYMMSCNYFWMLCEGVYLHTLIVVSVFAEGQRLWWYHVLGWGFPLIPTTAHAITRAVLFNDNCWLSVDTNLLYIIHG... | activation of phospholipase C activity adenylate cyclase-activating G protein-coupled receptor signaling pathway amylin receptor signaling pathway cell surface receptor signaling pathway negative regulation of ossification ossification osteoclast differentiation positive regulation of calcium-mediated signaling positiv... |
aortic valve development cell surface receptor signaling pathway cellular response to growth factor stimulus cellular response to lipopolysaccharide extrinsic apoptotic signaling pathway glial cell-neuron signaling immune response inflammatory response intrinsic apoptotic signaling pathway in response to DNA damage neg... | axon; membrane; membrane raft; neuronal cell body; perinuclear region of cytoplasm; varicosity | tumor necrosis factor binding tumor necrosis factor receptor activity ubiquitin protein ligase binding | Mus musculus | Disulfide bond Glycoprotein Membrane Phosphoprotein Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix | MAPAALWVAL | MAPAALWVALVFELQLWATGHTVPAQVVLTPYKPEPGYECQISQEYYDRKAQMCCAKCPPGQYVKHFCNKTSDTVCADCEASMYTQVWNQFRTCLSCSSSCTTDQVEIRACTKQQNRVCACEAGRYCALKTHSGSCRQCMRLSKCGPGFGVASSRAPNGNVLCKACAPGTFSDTTSSTDVCRPHRICSILAIPGNASTDAVCAPESPTLSAIPRTLYVSQPEPTRSQPLDQEPGPSQTPSILTSLGSTPIIEQSTKGGISLPIGLIVGVTSLGLLMLGLVNCIILVQRKKKPSCLQRDAKVPHVPDEKSQDAVGLEQQHL... | aortic valve development cell surface receptor signaling pathway cellular response to growth factor stimulus cellular response to lipopolysaccharide extrinsic apoptotic signaling pathway glial cell-neuron signaling immune response inflammatory response intrinsic apoptotic signaling pathway in response to DNA damage neg... |
cellular response to xenobiotic stimulus cerebellum development corpus callosum development globus pallidus development optic nerve development positive regulation of monoatomic ion transmembrane transport positive regulation of potassium ion transmembrane transport potassium ion transmembrane transport protein homooli... | axolemma; axon terminus; calyx of Held; cell surface; dendrite; dendrite membrane; neuron projection membrane; neuronal cell body; neuronal cell body membrane; postsynaptic membrane; presynaptic membrane; voltage-gated potassium channel complex | delayed rectifier potassium channel activity kinesin binding transmembrane transporter binding voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential | Rattus norvegicus | Alternative splicing Cell membrane Cell projection Glycoprotein Ion channel Ion transport Membrane Phosphoprotein Potassium Potassium channel Potassium transport Reference proteome Synapse Transmembrane Transmembrane helix Transport Voltage-gated channel | MGQGDESERI | MGQGDESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVVFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILR... | cellular response to xenobiotic stimulus cerebellum development corpus callosum development globus pallidus development optic nerve development positive regulation of monoatomic ion transmembrane transport positive regulation of potassium ion transmembrane transport potassium ion transmembrane transport protein homooli... |
chloride transmembrane transport inter-male aggressive behavior monoatomic ion transport negative regulation of synaptic transmission olfactory behavior regulation of circadian sleep/wake cycle regulation of olfactory learning response to mechanical stimulus response to xenobiotic stimulus sleep | axon; chloride channel complex; dendrite; membrane; neuron projection; neuron projection membrane; neuronal cell body membrane; plasma membrane; postsynaptic membrane; synapse | GABA-A receptor activity GABA-gated chloride ion channel activity neurotransmitter receptor activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | Drosophila melanogaster | Alternative splicing Cell membrane Cell projection Chloride Chloride channel Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Postsynaptic cell membrane Receptor Reference proteome RNA editing Signal Synapse Transmembrane Transmembrane helix Transport | MSDSKMDKLA | MSDSKMDKLARMAPLPRTPLLTIWLAINMALIAQETGHKRIHTVQAATGGGSMLGDVNISAILDSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAA... | chloride transmembrane transport inter-male aggressive behavior monoatomic ion transport negative regulation of synaptic transmission olfactory behavior regulation of circadian sleep/wake cycle regulation of olfactory learning response to mechanical stimulus response to xenobiotic stimulus sleep axon; chloride channel ... |
tricarboxylic acid cycle | cytoplasm | ATP binding GTP binding magnesium ion binding succinate-CoA ligase (ADP-forming) activity succinate-CoA ligase (GDP-forming) activity | Thermus thermophilus | 3D-structure GTP-binding Ligase Magnesium Metal-binding Nucleotide-binding Tricarboxylic acid cycle | MNLHEYQAKE | MNLHEYQAKEILARYGVPVPPGKVAYTPEEAKRIAEEFGKRVVIKAQVHVGGRGKAGGVKLADTPQEAYEKAQAILGMNIKGLTVKKVLVAEAVDIAKEYYAGLILDRAKKRVVLMLSKEGGVDIEEVAAERPEAIHKFWIDPHKGFRPFEAREMVKRAGLEGNLNKLAQVLVALYRAYEGVDASIAEINPLVVTTDGGIVAADAKIVLDDNALFRHPDLAELREVEAEHPLEVEASNYGFAYVKLDGNIGIIGNGAGLVMYTLDLVNRVGGKPANFLDIGGGAKADVVYNALKVVLKDPDVKGVFINIFGGITRADEVA... | tricarboxylic acid cycle cytoplasm ATP binding GTP binding magnesium ion binding succinate-CoA ligase (ADP-forming) activity succinate-CoA ligase (GDP-forming) activity Thermus thermophilus3D-structure GTP-binding Ligase Magnesium Metal-binding Nucleotide-binding Tricarboxylic acid cycle MNLHEYQAKE MNLHEYQAKEILARYGVPVP... |
embryonic hemopoiesis immune response interleukin-3-mediated signaling pathway positive regulation of cell population proliferation positive regulation of tyrosine phosphorylation of STAT protein | extracellular space | cytokine activity growth factor activity interleukin-3 receptor binding | Macaca mulatta | Cytokine Disulfide bond Glycoprotein Growth factor Reference proteome Secreted Signal | MSRLPVLLLL | MSRLPVLLLLHLLVSPGLQAPMTQTTSLKTSWAKCSNMIDEIITHLNQPPLPSPDFNNLNEEDQTILVEKNLRRSNLEAFSKAVKSLQNASAIESILKNLPPCLPMATAAPTRPPIRITNGDRNDFRRKLKFYLKTLENEQAQ | embryonic hemopoiesis immune response interleukin-3-mediated signaling pathway positive regulation of cell population proliferation positive regulation of tyrosine phosphorylation of STAT protein extracellular space cytokine activity growth factor activity interleukin-3 receptor binding Macaca mulatta Cytokine Disulfid... |
negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription regulation of DNA-templated transcription | protein-DNA complex | DNA-binding transcription activator activity DNA-binding transcription factor activity DNA-binding transcription repressor activity transcription cis-regulatory region binding | Bacillus subtilis | 3D-structure Activator DNA-binding Reference proteome Repressor Transcription Transcription regulation | MSNITIYDVA | MSNITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTTTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIVFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGHTDIAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGAVAMRLLTKLMNKEPVEEHIV... | negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription regulation of DNA-templated transcription protein-DNA complex DNA-binding transcription activator activity DNA-binding transcription factor activity DNA-binding transcription repressor activity transcription cis-regula... |
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