Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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photorespiration reductive pentose-phosphate cycle | chloroplast | magnesium ion binding monooxygenase activity ribulose-bisphosphate carboxylase activity | Glycine max | Acetylation Calvin cycle Carbon dioxide fixation Chloroplast Direct protein sequencing Disulfide bond Lyase Magnesium Metal-binding Methylation Monooxygenase Oxidoreductase Photorespiration Photosynthesis Plastid Reference proteome | MSPQTETKAS | MSPQTETKASVGFKAGVKDYKLTYYTPDYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYGLEPVAGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPTAYIKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIFKSQAETGEIKGHYLNATAGTCEEMMKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRL... | photorespiration reductive pentose-phosphate cycle chloroplast magnesium ion binding monooxygenase activity ribulose-bisphosphate carboxylase activity Glycine max Acetylation Calvin cycle Carbon dioxide fixation Chloroplast Direct protein sequencing Disulfide bond Lyase Magnesium Metal-binding Methylation Monooxygenas... |
BMP signaling pathway dorsal closure embryonic digestive tract morphogenesis female germ-line stem cell population maintenance follicle cell of egg chamber development imaginal disc-derived wing vein morphogenesis imaginal disc-derived wing vein specification larval fat body development maintenance of synapse structure... | dense core granule; endomembrane system; extracellular space; synapse | cytokine activity growth factor activity morphogen activity protein heterodimerization activity receptor ligand activity transforming growth factor beta receptor binding | Drosophila melanogaster | Cleavage on pair of basic residues Cytokine Developmental protein Disulfide bond Glycoprotein Growth factor Reference proteome Secreted Signal | MSGLRNTSEA | MSGLRNTSEAVAVLASLGLGMVLLMFVATTPPAVEATQSGIYIDNGKDQTIMHRVLSEDDKLDVSYEILEFLGIAERPTHLSSHQLSLRKSAPKFLLDVYHRITAEEGLSDQDEDDDYERGHRSRRSADLEEDEGEQQKNFITDLDKRAIDESDIIMTFLNKRHHNVDELRHEHGRRLWFDVSNVPNDNYLVMAELRIYQNANEGKWLTANREFTITVYAIGTGTLGQHTMEPLSSVNTTGDYVGWLELNVTEGLHEWLVKSKDNHGIYIGAHAVNRPDREVKLDDIGLIHRKVDDEFQPFMIGFFRGPELIKATAHSSH... | BMP signaling pathway dorsal closure embryonic digestive tract morphogenesis female germ-line stem cell population maintenance follicle cell of egg chamber development imaginal disc-derived wing vein morphogenesis imaginal disc-derived wing vein specification larval fat body development maintenance of synapse structure... |
activin receptor signaling pathway hematopoietic progenitor cell differentiation hemoglobin biosynthetic process male gonad development mesoderm development negative regulation of cell growth negative regulation of cell population proliferation negative regulation of G1/S transition of mitotic cell cycle ovarian follic... | activin A complex; extracellular region; extracellular space; inhibin A complex | cytokine activity growth factor activity hormone activity | Gallus gallus | Disulfide bond Glycoprotein Growth factor Hormone Reference proteome Secreted Signal | MPLLWKRGFL | MPLLWKRGFLLVICWIIVRSSPTPGSEGHSSVADCPSCALTTLSKDVPSSQPEMVEAVKKHILNMLHLRDRPNITQPVPKAALLNATKKLHVGKVGDDGYVEIEDDVGRRAEMNEVVEQTSEIITFAESGTPKKTLHFEISKEGSELSVVEHAEVWLFLKVSKANRSRTKVTIRLFQQQRQPKGNSEAAEDMEDMGLKGERSETLISEKAVDARKSTWHIFPISSSVQRLLDQGQSSLDVRIACDLCQETGASLVLLGKKKKKEDDGEGKEKDGGELTGEEEKEQSHRPFLMMLARHSEDRQHRRRERGLECDGKVNICC... | activin receptor signaling pathway hematopoietic progenitor cell differentiation hemoglobin biosynthetic process male gonad development mesoderm development negative regulation of cell growth negative regulation of cell population proliferation negative regulation of G1/S transition of mitotic cell cycle ovarian follic... |
activin receptor signaling pathway cellular response to insulin stimulus cellular response to starvation fat cell differentiation negative regulation of follicle-stimulating hormone secretion negative regulation of hepatocyte growth factor production negative regulation of insulin secretion positive regulation of folli... | extracellular space; perinuclear region of cytoplasm | cytokine activity growth factor activity hormone activity protein homodimerization activity | Gallus gallus | Cleavage on pair of basic residues Disulfide bond Glycoprotein Growth factor Hormone Reference proteome Secreted Signal | MDGAARRGVL | MDGAARRGVLAALLACGLLLLGAAATPTPPPAGSSPQDTCTSCGFRRPEEPGKVDGDFLEAVKRHILSRLQMRDRPNITHAVPKAAMVTALRKLHAGKVREDGRVEIPSLDGQASAGPPAHDPVSEIISFAETDDLASSRVRLYFFISNEGNQNLFVVQASLWLYLKLLPYVLEKGSRRKVRVKVYFQDPDTSNKWNVVEKKVDLKRSGWHTFPMTEAIQALFERGERRLNLDVQCEGCEEYSVLPIYVDPGEESHRPFLVVQARLADNKHRIRKRGLECDGRTNLCCRQQFYIDFRLIGWNDWIIAPSGYYGNYCEGSC... | activin receptor signaling pathway cellular response to insulin stimulus cellular response to starvation fat cell differentiation negative regulation of follicle-stimulating hormone secretion negative regulation of hepatocyte growth factor production negative regulation of insulin secretion positive regulation of folli... |
cardiac muscle hypertrophy in response to stress cGMP biosynthetic process cGMP-mediated signaling female pregnancy negative regulation of systemic arterial blood pressure neuropeptide signaling pathway positive regulation of cardiac muscle contraction positive regulation of heart rate positive regulation of potassium ... | cell projection; cytoplasm; extracellular space; perikaryon; protein-containing complex | hormone activity hormone receptor binding neuropeptide hormone activity neuropeptide receptor binding | Equus caballus | Cell projection Disulfide bond Hormone Phosphoprotein Reference proteome Secreted Signal Vasoactive Vasodilator | MGSFSTIMAS | MGSFSTIMASFLLFLAFQLQGQTRANPVYGSVSNGDLMDFKNLLDRLEDKMPLEDEVMPPQVLSDQSEEERAALSPLPEVPPWTGEVNPAQRDGGALGRGSWDSSDRSALLKSKLRALLAAPRSLRRSSCFGGRMDRIGAQSGLGCNSFRYRR | cardiac muscle hypertrophy in response to stress cGMP biosynthetic process cGMP-mediated signaling female pregnancy negative regulation of systemic arterial blood pressure neuropeptide signaling pathway positive regulation of cardiac muscle contraction positive regulation of heart rate positive regulation of potassium ... |
positive regulation by host of viral genome replication positive regulation of protein targeting to membrane positive regulation of viral process regulation of monoatomic ion transmembrane transport | azurophil granule membrane; blood microparticle; cytoskeleton; endoplasmic reticulum; extracellular exosome; extracellular space; melanosome; membrane; membrane raft; mitochondrion; perinuclear region of cytoplasm; plasma membrane; specific granule membrane; tertiary granule membrane; vesicle | identical protein binding protein homodimerization activity RNA polymerase binding | Homo sapiens | 3D-structure Alternative splicing Cell membrane Cytoplasm Cytoplasmic vesicle Cytoskeleton Direct protein sequencing Lipoprotein Membrane Palmitate Phosphoprotein Reference proteome | MAEKRHTRDS | MAEKRHTRDSEAQRLPDSFKDSPSKGLGPCGWILVAFSFLFTVITFPISIWMCIKIIKEYERAIIFRLGRILQGGAKGPGLFFILPCTDSFIKVDMRTISFDIPPQEILTKDSVTISVDGVVYYRVQNATLAVANITNADSATRLLAQTTLRNVLGTKNLSQILSDREEIAHNMQSTLDDATDAWGIKVERVEIKDVKLPVQLQRAMAAEAEASREARAKVIAAEGEMNASRALKEASMVITESPAALQLRYLQTLTTIAAEKNSTIVFPLPIDMLQGIIGAKHSHLG | positive regulation by host of viral genome replication positive regulation of protein targeting to membrane positive regulation of viral process regulation of monoatomic ion transmembrane transport azurophil granule membrane; blood microparticle; cytoskeleton; endoplasmic reticulum; extracellular exosome; extracellula... |
anti-Mullerian hormone signaling pathway gonadal mesoderm development Leydig cell differentiation Mullerian duct regression negative regulation of ovarian follicle development ovarian follicle development positive regulation of gene expression positive regulation of SMAD protein signal transduction preantral ovarian fo... | cytoplasm; extracellular region; extracellular space | growth factor activity signaling receptor binding transforming growth factor beta receptor binding type II transforming growth factor beta receptor binding | Mus musculus | Differentiation Disulfide bond Glycoprotein Gonadal differentiation Growth factor Reference proteome Secreted Signal | MQGPHLSPLV | MQGPHLSPLVLLLATMGAVLQPEAVENLATNTRGLIFLEDELWPPSSPPEPLCLVTVRGEGNTSRASLRVVGGLNSYEYAFLEAVQESRWGPQDLATFGVCSTDSQATLPALQRLGAWLGETGEQQLLVLHLAEVIWEPELLLKFQEPPPGGASRWEQALLVLYPGPGPQVTVTGTGLRGTQNLCPTRDTRYLVLTVDFPAGAWSGSGLILTLQPSREGATLSIDQLQAFLFGSDSRCFTRMTPTLVVLPPAEPSPQPAHGQLDTMPFPQPGLSLEPEALPHSADPFLETLTRLVRALRGPLTQASNTQLALDPGALASF... | anti-Mullerian hormone signaling pathway gonadal mesoderm development Leydig cell differentiation Mullerian duct regression negative regulation of ovarian follicle development ovarian follicle development positive regulation of gene expression positive regulation of SMAD protein signal transduction preantral ovarian fo... |
in utero embryonic development mannose metabolic process protein N-linked glycosylation protein N-linked glycosylation via asparagine UDP-N-acetylglucosamine catabolic process | Golgi medial cisterna; Golgi membrane; perinuclear region of cytoplasm | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity manganese ion binding protein N-acetylglucosaminyltransferase activity | Oryctolagus cuniculus | 3D-structure Cytoplasm Direct protein sequencing Disulfide bond Glycosyltransferase Golgi apparatus Manganese Membrane Metal-binding Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix | MLKKQSAGLV | MLKKQSAGLVLWGAILFVAWNALLLLFFWTRPVPSRLPSDNALDDDPASLTREVIRLAQDAEVELERQRGLLQQIREHHALWSQRWKVPTAAPPAQPHVPVTPPPAVIPILVIACDRSTVRRCLDKLLHYRPSAELFPIIVSQDCGHEETAQVIASYGSAVTHIRQPDLSNIAVQPDHRKFQGYYKIARHYRWALGQIFHNFNYPAAVVVEDDLEVAPDFFEYFQATYPLLKADPSLWCVSAWNDNGKEQMVDSSKPELLYRTDFFPGLGWLLLAELWAELEPKWPKAFWDDWMRRPEQRKGRACVRPEISRTMTFGRKG... | in utero embryonic development mannose metabolic process protein N-linked glycosylation protein N-linked glycosylation via asparagine UDP-N-acetylglucosamine catabolic process Golgi medial cisterna; Golgi membrane; perinuclear region of cytoplasm alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase act... |
chaperone-mediated protein folding negative regulation of microtubule polymerization or depolymerization negative regulation of neuron projection development | axonal growth cone; cytosol; microtubule; mitochondrion; nucleus | peptidyl-prolyl cis-trans isomerase activity tau protein binding | Oryctolagus cuniculus | 3D-structure Acetylation Chaperone Cytoplasm Cytoskeleton Direct protein sequencing Isomerase Isopeptide bond Methylation Microtubule Mitochondrion Nucleus Phosphoprotein Reference proteome Repeat Rotamase TPR repeat Ubl conjugation | MTAEEMKAAE | MTAEEMKAAESGAQSAPLPLEGVDISPKQDEGVLKVIKREGTGTETPMIGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAVATMKVGELCRITCKPEYAYGSAGSPPKIPPNATLVFEVELFEFKGEDLTDDEDGGIIRRIRTRGEGYARPNDGAIVEVALEGYYKDRLFDQRELRFEVGEGESLDLPCGLEKAIQRMEKGEHSILYLKPSYAFGNAGKEKFQIPPYAELKYEVHLKSFEKAKESWEMSSEEKLEQSAIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSSEEVQKAQALRLA... | chaperone-mediated protein folding negative regulation of microtubule polymerization or depolymerization negative regulation of neuron projection development axonal growth cone; cytosol; microtubule; mitochondrion; nucleus peptidyl-prolyl cis-trans isomerase activity tau protein binding Oryctolagus cuniculus 3D-structu... |
rhamnose transmembrane transport | plasma membrane | rhamnose transmembrane transporter activity symporter activity | Escherichia coli | Cell inner membrane Cell membrane Membrane Reference proteome Sugar transport Symport Transmembrane Transmembrane helix Transport | MSNAITMGIF | MSNAITMGIFWHLIGAASAACFYAPFKKVKKWSWETMWSVGGIVSWIILPWAISALLLPNFWAYYSSFSLSTRLPVFLFGAMWGIGNINYGLTMRYLGMSMGIGIAIGITLIVGTLMTPIINGNFDVLISTEGGRMTLLGVLVALIGVGIVTRAGQLKERKMGIKAEEFNLKKGLVLAVMCGIFSAGMSFAMNAAKPMHEAAAALGVDPLYVALPSYVVIMGGGAIINLGFCFIRLAKVKDLSLKADFSLAKSLIIHNVLLSTLGGLMWYLQFFFYAWGHARIPAQYDYISWMLHMSFYVLCGGIVGLVLKEWNNAGRRP... | rhamnose transmembrane transport plasma membrane rhamnose transmembrane transporter activity symporter activity Escherichia coli Cell inner membrane Cell membrane Membrane Reference proteome Sugar transport Symport Transmembrane Transmembrane helix Transport MSNAITMGIF MSNAITMGIFWHLIGAASAACFYAPFKKVKKWSWETMWSVGGIVSWIILP... |
actin cytoskeleton organization actin filament depolymerization actin filament organization aggregation involved in sorocarp development cell motility defense response to bacterium endocytosis gene expression hyperosmotic response intranuclear rod assembly mitotic cleavage furrow formation mitotic cytokinesis phagocyto... | actin cytoskeleton; anterior cell cortex; cell cortex; cell pole; cell projection; cell surface; cell tip; cleavage furrow; cortical cytoskeleton; extracellular matrix; intranuclear rod; mitotic spindle polar microtubule; pathogen-containing vacuole; phagocytic cup; phagocytic vesicle; plasma membrane; plasma membrane ... | actin filament binding protein self-association | Dictyostelium discoideum | Actin-binding Coiled coil Direct protein sequencing Reference proteome Repeat WD repeat | MSKVVRSSKY | MSKVVRSSKYRHVFAAQPKKEECYQNLKVTKSAWDSNYVAANTRYFGVIWDAAGGGSFAVIPHEASGKTTSVPLFNGHKSAVLDIAFHPFNENLVGSVSEDCNICIWGIPEGGLTDSISTPLQTLSGHKRKVGTISFNPVADNVAVTSSGDFLVKTWDVEQGKNLTTVEGHSDMITSCEWNHNGSQIVTTCKDKKARVFDPRTNSIVNEVVCHQGVKNSRAIFAKDKVITVGFSKTSERELHIYDPRAFTTPLSAQVVDSASGLLMPFYDADNSILYLAGKGDGNIRYYELVDESPYIHFLSEFKSATPQRGLCFLPKRC... | actin cytoskeleton organization actin filament depolymerization actin filament organization aggregation involved in sorocarp development cell motility defense response to bacterium endocytosis gene expression hyperosmotic response intranuclear rod assembly mitotic cleavage furrow formation mitotic cytokinesis phagocyto... |
carbon fixation carbon utilization photosynthesis | carboxysome | carbonate dehydratase activity zinc ion binding | Synechococcus elongatus | 3D-structure Bacterial microcompartment Carbon dioxide fixation Carboxysome Lyase Metal-binding Photosynthesis Reference proteome Zinc | MRKLIEGLRH | MRKLIEGLRHFRTSYYPSHRDLFEQFAKGQHPRVLFITCSDSRIDPNLITQSGMGELFVIRNAGNLIPPFGAANGGEGASIEYAIAALNIEHVVVCGHSHCGAMKGLLKLNQLQEDMPLVYDWLQHAQATRRLVLDNYSGYETDDLVEILVAENVLTQIENLKTYPIVRSRLFQGKLQIFGWIYEVESGEVLQISRTSSDDTGIDECPVRLPGSQEKAILGRCVVPLTEEVAVAPPEPEPVIAAVAAPPANYSSRGWLAPEQQQRIYRGNAS | carbon fixation carbon utilization photosynthesis carboxysome carbonate dehydratase activity zinc ion binding Synechococcus elongatus 3D-structure Bacterial microcompartment Carbon dioxide fixation Carboxysome Lyase Metal-binding Photosynthesis Reference proteome Zinc MRKLIEGLRH MRKLIEGLRHFRTSYYPSHRDLFEQFAKGQHPRVLFITC... |
angiotensin-activated signaling pathway carbon dioxide transport cellular response to fluid shear stress estrous cycle kidney development morphogenesis of an epithelium neuron cellular homeostasis odontogenesis of dentin-containing tooth one-carbon metabolic process osteoclast differentiation positive regulation of bon... | apical part of cell; axon; basolateral plasma membrane; cytoplasm; cytosol; extracellular space; microvillus; myelin sheath; plasma membrane | arylesterase activity carbonate dehydratase activity cyanamide hydratase activity zinc ion binding | Rattus norvegicus | Acetylation Cell membrane Cytoplasm Direct protein sequencing Lyase Membrane Metal-binding Phosphoprotein Reference proteome Zinc | MSHHWGYSKS | MSHHWGYSKSNGPENWHKEFPIANGDRQSPVDIDTGTAQHDPSLQPLLICYDKVASKSIVNNGHSFNVEFDDSQDFAVLKEGPLSGSYRLIQFHFHWGSSDGQGSEHTVNKKKYAAELHLVHWNTKYGDFGKAVQHPDGLAVLGIFLKIGPASQGLQKITEALHSIKTKGKRAAFANFDPCSLLPGNLDYWTYPGSLTTPPLLECVTWIVLKEPITVSSEQMSHFRKLNFNSEGEAEELMVDNWRPAQPLKNRKIKASFK | angiotensin-activated signaling pathway carbon dioxide transport cellular response to fluid shear stress estrous cycle kidney development morphogenesis of an epithelium neuron cellular homeostasis odontogenesis of dentin-containing tooth one-carbon metabolic process osteoclast differentiation positive regulation of bon... |
carbon utilization defense response to fungus negative regulation of stomatal complex development photosynthesis regulation of stomatal movement response to carbon dioxide response to cold | apoplast; chloroplast; chloroplast envelope; chloroplast stroma; chloroplast thylakoid membrane; cytosol; plasma membrane; stromule; thylakoid | carbonate dehydratase activity mRNA binding zinc ion binding | Arabidopsis thaliana | Acetylation Alternative splicing Cell membrane Chloroplast Lyase Membrane Phosphoprotein Plastid Reference proteome S-nitrosylation Transit peptide Zinc | MSTAPLSGFF | MSTAPLSGFFLTSLSPSQSSLQKLSLRTSSTVACLPPASSSSSSSSSSSSRSVPTLIRNEPVFAAPAPIIAPYWSEEMGTEAYDEAIEALKKLLIEKEELKTVAAAKVEQITAALQTGTSSDKKAFDPVETIKQGFIKFKKEKYETNPALYGELAKGQSPKYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDKVKYGGVGAAIEYAVLHLKVENIVVIGHSACGGIKGLMSFPLDGNNSTDFIEDWVKICLPAKSKVISELGDSAFEDQCGRCEREAVNVSLANLLTYPFVREGLVKGTLALKGGYYDFVKGA... | carbon utilization defense response to fungus negative regulation of stomatal complex development photosynthesis regulation of stomatal movement response to carbon dioxide response to cold apoplast; chloroplast; chloroplast envelope; chloroplast stroma; chloroplast thylakoid membrane; cytosol; plasma membrane; stromule... |
ADP biosynthetic process AMP metabolic process ATP metabolic process cellular response to hypoxia GTP metabolic process nucleobase-containing small molecule interconversion nucleoside triphosphate biosynthetic process phosphorylation regulation of oxidative phosphorylation ribonucleoside diphosphate biosynthetic proces... | cytoplasm; mitochondrial matrix; mitochondrion | adenylate kinase activity ATP binding GTP binding nucleoside diphosphate kinase activity nucleoside monophosphate kinase activity nucleoside triphosphate adenylate kinase activity | Homo sapiens | 3D-structure Acetylation ATP-binding GTP-binding Kinase Mitochondrion Nucleotide-binding Reference proteome Transferase | MASKLLRAVI | MASKLLRAVILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIKASTEVGEMAKQYIEKSLLVPDHVITRLMMSELENRRGQHWLLDGFPRTLGQAEALDKICEVDLVISLNIPFETLKDRLSRRWIHPPSGRVYNLDFNPPHVHGIDDVTGEPLVQQEDDKPEAVAARLRQYKDVAKPVIELYKSRGVLHQFSGTETNKIWPYVYTLFSNKITPIQSKEAY | ADP biosynthetic process AMP metabolic process ATP metabolic process cellular response to hypoxia GTP metabolic process nucleobase-containing small molecule interconversion nucleoside triphosphate biosynthetic process phosphorylation regulation of oxidative phosphorylation ribonucleoside diphosphate biosynthetic proces... |
deoxyribonucleoside monophosphate biosynthetic process digestive tract development DNA synthesis involved in mitotic DNA replication fetal process involved in parturition liver development nucleotide biosynthetic process phosphorylation protein homotetramerization response to copper ion response to cortisol response to... | cytoplasm; nucleus | ATP binding identical protein binding thymidine kinase activity zinc ion binding | Rattus norvegicus | Acetylation ATP-binding Cytoplasm DNA synthesis Kinase Nucleotide-binding Phosphoprotein Reference proteome Transferase Ubl conjugation | MSYINLPTVL | MSYINLPTVLPISPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQYKCLVIKYAKDTRYSNSFSTHDRNTMDALPACMLKDVAQEALGVAVIGIDEGQFFPDIVDFCETMANTGKTVIV | deoxyribonucleoside monophosphate biosynthetic process digestive tract development DNA synthesis involved in mitotic DNA replication fetal process involved in parturition liver development nucleotide biosynthetic process phosphorylation protein homotetramerization response to copper ion response to cortisol response to... |
aromatic compound catabolic process carboxylic acid catabolic process cholesterol metabolic process organophosphate catabolic process phosphatidylcholine metabolic process positive regulation of binding positive regulation of cholesterol efflux positive regulation of transporter activity response to toxic substance | blood microparticle; endoplasmic reticulum membrane; extracellular exosome; extracellular region; extracellular space; high-density lipoprotein particle; spherical high-density lipoprotein particle | acyl-L-homoserine-lactone lactonohydrolase activity aryldialkylphosphatase activity arylesterase activity calcium ion binding phospholipid binding protein homodimerization activity | Homo sapiens | 3D-structure Calcium Direct protein sequencing Disulfide bond Glycoprotein HDL Hydrolase Metal-binding Reference proteome Secreted Signal | MAKLIALTLL | MAKLIALTLLGMGLALFRNHQSSYQTRLNALREVQPVELPNCNLVKGIETGSEDLEILPNGLAFISSGLKYPGIKSFNPNSPGKILLMDLNEEDPTVLELGITGSKFDVSSFNPHGISTFTDEDNAMYLLVVNHPDAKSTVELFKFQEEEKSLLHLKTIRHKLLPNLNDIVAVGPEHFYGTNDHYFLDPYLQSWEMYLGLAWSYVVYYSPSEVRVVAEGFDFANGINISPDGKYVYIAELLAHKIHVYEKHANWTLTPLKSLDFNTLVDNISVDPETGDLWVGCHPNGMKIFFYDSENPPASEVLRIQNILTEEPKVTQV... | aromatic compound catabolic process carboxylic acid catabolic process cholesterol metabolic process organophosphate catabolic process phosphatidylcholine metabolic process positive regulation of binding positive regulation of cholesterol efflux positive regulation of transporter activity response to toxic substance blo... |
response to organophosphorus | high-density lipoprotein particle | acyl-L-homoserine-lactone lactonohydrolase activity antioxidant activity aryldialkylphosphatase activity arylesterase activity calcium ion binding | Oryctolagus cuniculus | Antioxidant Calcium Direct protein sequencing Disulfide bond Glycoprotein HDL Hydrolase Metal-binding Reference proteome Secreted Signal | MAKLTALTLL | MAKLTALTLLGLGLALFDGQKSSFQTRFNVHREVTPVELPNCNLVKGIDNGSEDLEILPNGLAFISAGLKYPGIMSFDPDKPGKILLMDLNEKDPVVLELSITGSTFDLSSFNPHGISTFTDEDNIVYLMVVNHPDSKSTVELFKFQEKEKSLLHLKTIRHKLLPSVNDIVAVGPEHFYATNDHYFIDPYLKSWEMHLGLAWSFVTYYSPNDVRVVAEGFDFANGINISPDGKYVYIAELLAHKIHVYEKHANWTLTPLKSLDFNTLVDNISVDPVTGDLWVGCHPNGMRIFYYDPKNPPASEVLRIQDILSKEPKVTVA... | response to organophosphorus high-density lipoprotein particle acyl-L-homoserine-lactone lactonohydrolase activity antioxidant activity aryldialkylphosphatase activity arylesterase activity calcium ion binding Oryctolagus cuniculus Antioxidant Calcium Direct protein sequencing Disulfide bond Glycoprotein HDL Hydrolase ... |
positive regulation of gene expression positive regulation of peptidyl-tyrosine phosphorylation protein homooligomerization protein insertion into plasma membrane | basement membrane; plasma membrane; side of membrane; synaptic cleft | copper ion binding | Gallus gallus | 3D-structure Amyloid Cell membrane Copper Direct protein sequencing Disulfide bond Glycoprotein GPI-anchor Lipoprotein Membrane Metal-binding Prion Reference proteome Repeat Signal | MARLLTTCCL | MARLLTTCCLLALLLAACTDVALSKKGKGKPSGGGWGAGSHRQPSYPRQPGYPHNPGYPHNPGYPHNPGYPHNPGYPHNPGYPQNPGYPHNPGYPGWGQGYNPSSGGSYHNQKPWKPPKTNFKHVAGAAAAGAVVGGLGGYAMGRVMSGMNYHFDSPDEYRWWSENSARYPNRVYYRDYSSPVPQDVFVADCFNITVTEYSIGPAAKKNTSEAVAAANQTEVEMENKVVTKVIREMCVQQYREYRLASGIQLHPADTWLAVLLLLLTTLFAMH | positive regulation of gene expression positive regulation of peptidyl-tyrosine phosphorylation protein homooligomerization protein insertion into plasma membrane basement membrane; plasma membrane; side of membrane; synaptic cleft copper ion binding Gallus gallus 3D-structure Amyloid Cell membrane Copper Direct protei... |
photosynthetic electron transport chain | plasma membrane | copper ion binding electron transfer activity oxidoreductase activity | Chloroflexus aurantiacus | 3D-structure Cell membrane Copper Direct protein sequencing Electron transport Glycoprotein Membrane Metal-binding Reference proteome Signal Transport | MSWRGSGRSN | MSWRGSGRSNFRSRSSSNGGSTFSGGSAGGPPLIVMMGLAFGAGLIMLIVMIASNATAGGFVAATPRPTATPRPTAAPAPTQPPAAQPTTAPATQAANAPGGSNVVNETPAQTVEVRAAPDALAFAQTSLSLPANTVVRLDFVNQNNLGVQHNWVLVNGGDDVAAAVNTAAQNNADALFVPPPDTPNALAWTAMLNAGESGSVTFRTPAPGTYLYICTFPGHYLAGMKGTLTVTP | photosynthetic electron transport chain plasma membrane copper ion binding electron transfer activity oxidoreductase activity Chloroflexus aurantiacus 3D-structure Cell membrane Copper Direct protein sequencing Electron transport Glycoprotein Membrane Metal-binding Reference proteome Signal Transport MSWRGSGRSN MSWRGSG... |
tetrahydrobiopterin biosynthetic process | mitochondrion | 6-pyruvoyltetrahydropterin synthase activity identical protein binding metal ion binding | Rattus norvegicus | 3D-structure Direct protein sequencing Lyase Metal-binding Phenylketonuria Phosphoprotein Reference proteome Tetrahydrobiopterin biosynthesis Zinc | MNAAVGLRRR | MNAAVGLRRRARLSRLVSFSASHRLHSPSLSAEENLKVFGKCNNPNGHGHNYKVVVTIHGEIDPVTGMVMNLTDLKEYMEEAIMKPLDHKNLDLDVPYFADVVSTTENVAVYIWENLQRLLPVGALYKVKVYETDNNIVVYKGE | tetrahydrobiopterin biosynthetic process mitochondrion 6-pyruvoyltetrahydropterin synthase activity identical protein binding metal ion binding Rattus norvegicus 3D-structure Direct protein sequencing Lyase Metal-binding Phenylketonuria Phosphoprotein Reference proteome Tetrahydrobiopterin biosynthesis Zinc MNAAVGLRRR ... |
cytokinetic process phagocytosis | cytoplasm; melanosome; midbody; nuclear envelope; nucleoplasm; spindle | calcium ion binding calcium-dependent phospholipid binding S100 protein binding | Bos taurus | Acetylation Alternative splicing Annexin Calcium Calcium/phospholipid-binding Cell cycle Cell division Cytoplasm Cytoskeleton Direct protein sequencing Nucleus Reference proteome Repeat | MSYPGYPPPA | MSYPGYPPPAGGYPPGAPGGGAWGGAGYPPPTMPPIGLDNVANYAGQFNQDYLSGVAANMSGTFGGANVPNLYPGAPGGGYPPVPPGGFGQPPPAQQPVPSYGMYPPPGGNPTSGMPSYPPYPGAPVPGQPMLPPGQQPPGVYPGQPPMTYPGQSPVPPPGQQPVPSYPGYSGSGTVTPAVSPAQFGNRGTITDASGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDAYEIKEAIKGAGTDEACLIEILASRSNEHIRELNRVYKTEFKKTL... | cytokinetic process phagocytosis cytoplasm; melanosome; midbody; nuclear envelope; nucleoplasm; spindle calcium ion binding calcium-dependent phospholipid binding S100 protein binding Bos taurus Acetylation Alternative splicing Annexin Calcium Calcium/phospholipid-binding Cell cycle Cell division Cytoplasm Cytoskeleton... |
cell differentiation negative regulation of Golgi to plasma membrane protein transport positive regulation of Golgi to plasma membrane protein transport | apical plasma membrane; basolateral plasma membrane; cytoplasm; cytoplasmic vesicle; exocytic vesicle; extracellular exosome; extracellular space; membrane; membrane raft; nucleoplasm; plasma membrane | calcium ion binding calcium-dependent phospholipid binding phosphatidylglycerol binding phosphatidylserine binding | Homo sapiens | 3D-structure Alternative splicing Annexin Calcium Calcium/phospholipid-binding Cell membrane Cytoplasmic vesicle Lipoprotein Membrane Myristate Reference proteome Repeat | MGNRHAKASS | MGNRHAKASSPQGFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVALLH | cell differentiation negative regulation of Golgi to plasma membrane protein transport positive regulation of Golgi to plasma membrane protein transport apical plasma membrane; basolateral plasma membrane; cytoplasm; cytoplasmic vesicle; exocytic vesicle; extracellular exosome; extracellular space; membrane; membrane r... |
DNA replication | host cell nucleus | ATP binding DNA binding endodeoxyribonuclease activity, producing 5'-phosphomonoesters helicase activity metal ion binding nucleotidyltransferase activity structural molecule activity | Tomato yellow leaf curl Sardinia virus | 3D-structure ATP-binding Covalent protein-DNA linkage DNA replication DNA-binding Endonuclease Helicase Host nucleus Host-virus interaction Hydrolase Metal-binding Multifunctional enzyme Nuclease Nucleotide-binding Nucleotidyltransferase Reference proteome Transferase | MPRSGRFSIK | MPRSGRFSIKAKNYFLTYPKCDLTKENALSQITNLQTPTNKLFIKICRELHENGEPHLHILIQFEGKYNCTNQRFFDLVSPTRSAHFHPNIQGAKSSSDVKSYIDKDGDVLEWGTFQIDGRSARGGQQTANDAYAKAINAGSKSQALDVIKELAPRDYVLHFHNINSNLDKVFQVPPAPYVSPFLSSSFDQVPDELEHWVSENVMDAAARPWRPVSIVIEGDSRTGKTTWARSLGPHNYLCGHLDLSQKVYSNNAWYNVIDDVDPHYLKHFKEFMGAQRDWQSNTKYGKPIQIKGGIPTIFLCNPGPQSSFKEYLDEEKN... | DNA replication host cell nucleus ATP binding DNA binding endodeoxyribonuclease activity, producing 5'-phosphomonoesters helicase activity metal ion binding nucleotidyltransferase activity structural molecule activity Tomato yellow leaf curl Sardinia virus 3D-structure ATP-binding Covalent protein-DNA linkage DNA repli... |
negative regulation of activation of membrane attack complex negative regulation of apoptotic process negative regulation of complement activation negative regulation of complement-dependent cytotoxicity positive regulation of T cell proliferation regulation of complement activation regulation of complement-dependent c... | cell surface; compact myelin; external side of plasma membrane; extracellular space; plasma membrane; sarcolemma | complement binding | Rattus norvegicus | Cell membrane Direct protein sequencing Disulfide bond Glycoprotein GPI-anchor Lipoprotein Membrane Reference proteome Signal | MRARRGFILL | MRARRGFILLLLLAVLCSTGVSLRCYNCLDPVSSCKTNSTCSPNLDACLVAVSGKQVYQQCWRFSDCNAKFILSRLEIANVQYRCCQADLCNKSFEDKPNNGAISLLGKTALLVTSVLAAILKPCF | negative regulation of activation of membrane attack complex negative regulation of apoptotic process negative regulation of complement activation negative regulation of complement-dependent cytotoxicity positive regulation of T cell proliferation regulation of complement activation regulation of complement-dependent c... |
proteolysis | host cell cytoplasm; T=13 icosahedral viral capsid | metal ion binding serine-type peptidase activity structural molecule activity | Avian infectious bursal disease virus | Capsid protein Host cytoplasm Hydrolase Metal-binding Protease Serine protease T=13 icosahedral capsid protein Virion | MTNLMDHTQQ | MTNLMDHTQQIVPFIRSLLMPTTGPASIPDDTLEKHTLRSETSTYNLTVGDTGSGLIVFFPGFPGSVVGAHYTLQSSGSYQFDQMLLTAQNLPVSYNYCRLVSRSLTVRSSTLPGGVYALNGTINAVTFQGSLSELTDYSYNGLMSATANINDKIGNVLVGEGVTVLSLPTSYDLSYVRLGDPIPAAGLDPKLMATCDSSDRPRVYTVTAADEYQFSSQLIPSGVKTTLFTANIDALTSLSVGGELIFSQVTIHSIEVDVTIYFIGFDGTEVTVKAVATDFGLTTGTNNLVPFNLGGPTSEITQPITSMKLEVVTYKRGG... | proteolysis host cell cytoplasm; T=13 icosahedral viral capsid metal ion binding serine-type peptidase activity structural molecule activity Avian infectious bursal disease virus Capsid protein Host cytoplasm Hydrolase Metal-binding Protease Serine protease T=13 icosahedral capsid protein Virion MTNLMDHTQQ MTNLMDHTQQ... |
cellular response to metal ion NAD biosynthetic process phosphorylation protein homotetramerization response to alkaline pH | adenylyltransferase complex; catalytic complex; cytoplasm; plasma membrane | ATP binding cis-regulatory region sequence-specific DNA binding identical protein binding magnesium ion binding nicotinamide-nucleotide adenylyltransferase activity ribosylnicotinamide kinase activity | Escherichia coli | ATP-binding Cell membrane Cytoplasm DNA-binding Kinase Membrane Multifunctional enzyme NAD Nucleotide-binding Pyridine nucleotide biosynthesis Reference proteome Repressor Transcription Transcription regulation Transferase | MSSFDYLKTA | MSSFDYLKTAIKQQGCTLQQVADASGMTKGYLSQLLNAKIKSPSAQKLEALHRFLGLEFPRQKKTIGVVFGKFYPLHTGHIYLIQRACSQVDELHIIMGFDDTRDRALFEDSAMSQQPTVPDRLRWLLQTFKYQKNIRIHAFNEEGMEPYPHGWDVWSNGIKKFMAEKGIQPDLIYTSEEADAPQYMEHLGIETVLVDPKRTFMSISGAQIRENPFRYWEYIPTEVKPFFVRTVAILGGESSGKSTLVNKLANIFNTTSAWEYGRDYVFSHLGGDEIALQYSDYDKIALGHAQYIDFAVKYANKVAFIDTDFVTTQAFCK... | cellular response to metal ion NAD biosynthetic process phosphorylation protein homotetramerization response to alkaline pH adenylyltransferase complex; catalytic complex; cytoplasm; plasma membrane ATP binding cis-regulatory region sequence-specific DNA binding identical protein binding magnesium ion binding nicotinam... |
pentose-phosphate shunt pentose-phosphate shunt, non-oxidative branch | cytosol | magnesium ion binding manganese ion binding protein homodimerization activity thiamine pyrophosphate binding transketolase activity | Escherichia coli | 3D-structure Acetylation Calcium Magnesium Metal-binding Reference proteome Thiamine pyrophosphate Transferase | MSSRKELANA | MSSRKELANAIRALSMDAVQKAKSGHPGAPMGMADIAEVLWRDFLKHNPQNPSWADRDRFVLSNGHGSMLIYSLLHLTGYDLPMEELKNFRQLHSKTPGHPEVGYTAGVETTTGPLGQGIANAVGMAIAEKTLAAQFNRPGHDIVDHYTYAFMGDGCMMEGISHEVCSLAGTLKLGKLIAFYDDNGISIDGHVEGWFTDDTAMRFEAYGWHVIRDIDGHDAASIKRAVEEARAVTDKPSLLMCKTIIGFGSPNKAGTHDSHGAPLGDAEIALTREQLGWKYAPFEIPSEIYAQWDAKEAGQAKESAWNEKFAAYAKAYPQ... | pentose-phosphate shunt pentose-phosphate shunt, non-oxidative branch cytosol magnesium ion binding manganese ion binding protein homodimerization activity thiamine pyrophosphate binding transketolase activity Escherichia coli 3D-structure Acetylation Calcium Magnesium Metal-binding Reference proteome Thiamine pyrophos... |
response to antibiotic response to toxic substance xenobiotic detoxification by transmembrane export across the cell outer membrane xenobiotic detoxification by transmembrane export across the plasma membrane | efflux pump complex; outer membrane-bounded periplasmic space; periplasmic side of plasma membrane; plasma membrane | identical protein binding xenobiotic transmembrane transporter activity | Escherichia coli | Antibiotic resistance Cell inner membrane Cell membrane Coiled coil Membrane Reference proteome Transmembrane Transmembrane helix Transport | MSANAETQTP | MSANAETQTPQQPVKKSGKRKRLLLLLTLLFIIIAVAIGIYWFLVLRHFEETDDAYVAGNQIQIMSQVSGSVTKVWADNTDFVKEGDVLVTLDPTDARQAFEKAKTALASSVRQTHQLMINSKQLQANIEVQKIALAKAQSDYNRRVPLGNANLIGREELQHARDAVTSAQAQLDVAIQQYNANQAMILGTKLEDQPAVQQAATEVRNAWLALERTRIISPMTGYVSRRAVQPGAQISPTTPLMAVVPATNMWVDANFKETQIANMRIGQPVTITTDIYGDDVKYTGKVVGLDMGTGSAFSLLPAQNATGNWIKVVQRLP... | response to antibiotic response to toxic substance xenobiotic detoxification by transmembrane export across the cell outer membrane xenobiotic detoxification by transmembrane export across the plasma membrane efflux pump complex; outer membrane-bounded periplasmic space; periplasmic side of plasma membrane; plasma memb... |
cell redox homeostasis NADP metabolic process | cytosol | dihydrolipoyl dehydrogenase activity flavin adenine dinucleotide binding identical protein binding NAD(P)+ transhydrogenase (B-specific) activity NAD(P)+ transhydrogenase activity | Escherichia coli | Cytoplasm Direct protein sequencing FAD Flavoprotein NAD NADP Oxidoreductase Reference proteome | MPHSYDYDAI | MPHSYDYDAIVIGSGPGGEGAAMGLVKQGARVAVIERYQNVGGGCTHWGTIPSKALRHAVSRIIEFNQNPLYSDHSRLLRSSFADILNHADNVINQQTRMRQGFYERNHCEILQGNARFVDEHTLALDCPDGSVETLTAEKFVIACGSRPYHPTDVDFTHPRIYDSDSILSMHHEPRHVLIYGAGVIGCEYASIFRGMDVKVDLINTRDRLLAFLDQEMSDSLSYHFWNSGVVIRHNEEYEKIEGCDDGVIMHLKSGKKLKADCLLYANGRTGNTDSLALQNIGLETDSRGQLKVNSMYQTAQPHVYAVGDVIGYPSLAS... | cell redox homeostasis NADP metabolic process cytosol dihydrolipoyl dehydrogenase activity flavin adenine dinucleotide binding identical protein binding NAD(P)+ transhydrogenase (B-specific) activity NAD(P)+ transhydrogenase activity Escherichia coli Cytoplasm Direct protein sequencing FAD Flavoprotein NAD NADP Oxidore... |
animal organ regeneration egg activation liver development myoblast differentiation myoblast fusion negative regulation of type B pancreatic cell apoptotic process regulation of protein catabolic process | cytoplasm; cytosol; membrane; postsynaptic density | calcium-dependent cysteine-type endopeptidase inhibitor activity protease binding | Rattus norvegicus | 3D-structure Acetylation Alternative splicing Isopeptide bond Phosphoprotein Protease inhibitor Reference proteome Repeat Thiol protease inhibitor Ubl conjugation | MSRPGPKPAA | MSRPGPKPAASSRPRRGAAASHTQEHVNEKNIGSSSKPAEKKGSDEVTASSAATGTSPRMSTTGAKAVKIESEKSQSSEPPVIHEKKPKGKPKEGSEPQTLPKHASDTGSKHAHKEKALSRSNEQIVSEKSSESKTKFQDAPSADGESVAGGVTVATASDKVVVKKKEKKSLTPTLPMESTLNKLSDKSGVNAALDDLIDTLGECEDTNKDDPPYTGPVVLDPMDSTYLEALGIKEGTIPPEYRKLLEKNEAITGPLPDSPKPMGIDHAIDALSSDFTCSSPTGKQTEKEKSTGESSKAQSAGVTRSAVPPQEKKRKVEE... | animal organ regeneration egg activation liver development myoblast differentiation myoblast fusion negative regulation of type B pancreatic cell apoptotic process regulation of protein catabolic process cytoplasm; cytosol; membrane; postsynaptic density calcium-dependent cysteine-type endopeptidase inhibitor activity ... |
cellular response to heat chaperone-mediated protein folding defense response to bacterium innate immune response protein folding protein stabilization | cytosol; perinuclear region of cytoplasm; plasma membrane; protein-containing complex | ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone unfolded protein binding | Arabidopsis thaliana | ATP-binding Chaperone Cytoplasm Immunity Innate immunity Nucleotide-binding Phosphoprotein Plant defense Reference proteome Stress response | MADAETFAFQ | MADAETFAFQAEINQLLSLIINTFYSNKEIFLRELISNSSDALDKIRFESLTDKSKLDGQPELFIRLVPDKSNKTLSIIDSGIGMTKADLVNNLGTIARSGTKEFMEALQAGADVSMIGQFGVGFYSAYLVAEKVVVTTKHNDDEQYVWESQAGGSFTVTRDVDGEPLGRGTKITLFLKDDQLEYLEERRLKDLVKKHSEFISYPIYLWTEKTTEKEISDDEDEDEPKKENEGEVEEVDEEKEKDGKKKKKIKEVSHEWELINKQKPIWLRKPEEITKEEYAAFYKSLTNDWEDHLAVKHFSVEGQLEFKAILFVPKRAP... | cellular response to heat chaperone-mediated protein folding defense response to bacterium innate immune response protein folding protein stabilization cytosol; perinuclear region of cytoplasm; plasma membrane; protein-containing complex ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone unfold... |
dopamine catabolic process hydrogen peroxide biosynthetic process negative regulation of serotonin secretion phenylethylamine catabolic process positive regulation of dopamine metabolic process response to aluminum ion response to corticosterone response to ethanol response to lipopolysaccharide response to selenium io... | dendrite; mitochondrial envelope; mitochondrial outer membrane; mitochondrion; neuronal cell body | aliphatic amine oxidase activity electron transfer activity flavin adenine dinucleotide binding identical protein binding monoamine oxidase activity phenethylamine:oxygen oxidoreductase (deaminating) activity primary amine oxidase activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Direct protein sequencing FAD Flavoprotein Membrane Mitochondrion Mitochondrion outer membrane Oxidoreductase Reference proteome Transmembrane Transmembrane helix | MSNKCDVVVV | MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGE... | dopamine catabolic process hydrogen peroxide biosynthetic process negative regulation of serotonin secretion phenylethylamine catabolic process positive regulation of dopamine metabolic process response to aluminum ion response to corticosterone response to ethanol response to lipopolysaccharide response to selenium io... |
negative regulation of DNA-templated transcription negative regulation of monoatomic ion transmembrane transport protein targeting signal transduction small GTPase mediated signal transduction substantia nigra development | cytoplasm; cytosol; extracellular exosome; focal adhesion; membrane; protein-containing complex; synapse | 14-3-3 protein binding identical protein binding protein domain specific binding transmembrane transporter binding | Homo sapiens | 3D-structure Acetylation Cytoplasm Direct protein sequencing Isopeptide bond Nitration Phosphoprotein Reference proteome Ubl conjugation | MEKTELIQKA | MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAWRVISSIEQKTDTSDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVFYLKMKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFYYEILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECDAAEGAEN | negative regulation of DNA-templated transcription negative regulation of monoatomic ion transmembrane transport protein targeting signal transduction small GTPase mediated signal transduction substantia nigra development cytoplasm; cytosol; extracellular exosome; focal adhesion; membrane; protein-containing complex; s... |
endocytosis intracellular protein transport vesicle-mediated transport | AP-2 adaptor complex; cellular bud neck; endocytic vesicle | clathrin binding | Saccharomyces cerevisiae | Cell membrane Coated pit Endocytosis Membrane Phosphoprotein Protein transport Reference proteome Transport | MSDQKVFARY | MSDQKVFARYKANEIVTDLQHFGVKKFKSNITRRKNALRKIIANLVLGNYGEMSVLFSELLKFWQIEDDLEVKRICHEYIRVIGALKPQQAREALPFIMDDFKSRDEKLQIMALRTLVLVPVKELSDQAFDCIISLVNHKSPPEQVTRTAIYALLDLDEIDHERVLGLSSILHDIVKAQSSSPEVIVAALHTLYSIHEKNANMEPFRIPLELAFDMLELLPELNEWNKATVLEVLTTSVVPQHYLDTHEMIELALPYLQQVNTYVVLNSLKFIMYLLNYVDVIKETLAEKLSNSVIALLDKPPELQFLVLRNVILLLLSR... | endocytosis intracellular protein transport vesicle-mediated transport AP-2 adaptor complex; cellular bud neck; endocytic vesicle clathrin binding Saccharomyces cerevisiae Cell membrane Coated pit Endocytosis Membrane Phosphoprotein Protein transport Reference proteome Transport MSDQKVFARY MSDQKVFARYKANEIVTDLQHFGVKKFK... |
cobalamin transport cobalt ion transport | apical plasma membrane; endosome; extracellular region; extracellular space; lysosomal lumen; microvillus | cargo receptor ligand activity cobalamin binding | Homo sapiens | 3D-structure Alternative splicing Cobalt Cobalt transport Disease variant Disulfide bond Glycoprotein Ion transport Phosphoprotein Reference proteome Secreted Signal Transport | MAWFALYLLS | MAWFALYLLSLLWATAGTSTQTQSSCSVPSAQEPLVNGIQVLMENSVTSSAYPNPSILIAMNLAGAYNLKAQKLLTYQLMSSDNNDLTIGQLGLTIMALTSSCRDPGDKVSILQRQMENWAPSSPNAEASAFYGPSLAILALCQKNSEATLPIAVRFAKTLLANSSPFNVDTGAMATLALTCMYNKIPVGSEEGYRSLFGQVLKDIVEKISMKIKDNGIIGDIYSTGLAMQALSVTPEPSKKEWNCKKTTDMILNEIKQGKFHNPMSIAQILPSLKGKTYLDVPQVTCSPDHEVQPTLPSNPGPGPTSASNITVIYTINN... | cobalamin transport cobalt ion transport apical plasma membrane; endosome; extracellular region; extracellular space; lysosomal lumen; microvillus cargo receptor ligand activity cobalamin binding Homo sapiens 3D-structure Alternative splicing Cobalt Cobalt transport Disease variant Disulfide bond Glycoprotein Ion trans... |
C21-steroid hormone metabolic process hippocampus development progesterone metabolic process regulation of steroid biosynthetic process response to corticosterone steroid biosynthetic process | cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; mitochondrial membrane | 3-beta-hydroxy-delta5-steroid dehydrogenase activity 3-keto sterol reductase activity 5alpha-androstane-3beta,17beta-diol dehydrogenase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor steroid binding steroid dehydrogenase activity | Rattus norvegicus | Acetylation Endoplasmic reticulum Lipid metabolism Membrane Mitochondrion NADP Oxidoreductase Reference proteome Steroid metabolism Transmembrane Transmembrane helix | MPGWSCLVTG | MPGWSCLVTGAGGFLGQRIVQMLVQEKELQEVRVLYRTFSPKHKEELSKLQTKAKVTVLRGDIVDAQFLRRACQGMSVIIHTAAALDIAGFLPRQTILDVNVKGTQLLLDACVEASVPAFIYSSSTGVAGPNSYKETILNDREEEHRESTWSNPYPYSKRMAEKAVLAANGSILKNGGTFHTCALRLPFIYGEESQIISTMVNRALKNNSIIKRHATFSIANPVYVGNAAWAHILAARGLRDPEKSQSIQGQFYYISDDTPHQSYDDLNYTLSKEWGFCLDSSWSLPLPLLYWLAFLLETVSFLLRPFYNYRPPFNRFMV... | C21-steroid hormone metabolic process hippocampus development progesterone metabolic process regulation of steroid biosynthetic process response to corticosterone steroid biosynthetic process cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; mitochondrial membrane 3-beta-hydroxy-delta... |
C21-steroid hormone metabolic process hippocampus development response to corticosterone steroid biosynthetic process | cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; mitochondrial membrane | 3-beta-hydroxy-delta5-steroid dehydrogenase activity 3-keto sterol reductase activity 5alpha-androstane-3beta,17beta-diol dehydrogenase activity cholesterol dehydrogenase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor steroid delta-isomerase activity | Macaca mulatta | Endoplasmic reticulum Isomerase Lipid metabolism Membrane Mitochondrion Multifunctional enzyme NAD NADP Oxidoreductase Reference proteome Steroid metabolism Steroidogenesis Transmembrane Transmembrane helix | MTGWSCLVTG | MTGWSCLVTGAGGFLGQRIVRLLVEEKELKEIRVLDKAFRPELREEFSKLQNKTKLTVLEGDILDEPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTSTLEVAGPNSYKEIIQNGHEEEPLENTWPAPYPYSKKLAEKAVLAANGWTLKNGGTLYTCALRPMYIYGEGGPFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRALRDPKKAPSVQGQFYYISDDTPHQSYDNLNYILSKEFGLCLDSRWSLPLALMYWIGFLLEVVSFLLSPVYSYQPPFNRHTV... | C21-steroid hormone metabolic process hippocampus development response to corticosterone steroid biosynthetic process cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; mitochondrial membrane 3-beta-hydroxy-delta5-steroid dehydrogenase activity 3-keto sterol reductase activity 5alpha-a... |
defense response to bacterium disruption by virus of host cell wall peptidoglycan during virus entry disruption of host cell envelope during viral entry killing of cells of another organism peptidoglycan metabolic process | membrane; viral inner membrane; virion membrane | lysozyme activity lytic transglycosylase activity | Enterobacteria phage PRD1 | Alternative initiation Antimicrobial Bacteriolytic enzyme Capsid inner membrane protein Degradation of host cell envelope components during virus entry Degradation of host peptidoglycans during virus entry Direct protein sequencing Lyase Membrane Reference proteome Transmembrane Transmembrane helix Viral genome ejectio... | MSGALQWWET | MSGALQWWETIGAASAQYNLDPRLVAGVVQTESSGNPRTTSGVGAMGLMQLMPATAKSLGVTNAYDPTQNIYGGAALLRENLDRYGDVNTALLAYHGGTNQANWGAKTKSYPGKVMKNINLLFGNSGPVVTPAAGIAPVSGAQEMTAVNISDYTAPDLTGLTMGAGSPDFTGGASGSWGEENIPWYRVDKHVANAAGSAYDAVTDAVSAPVEAAGNYALRGVVIIAAVAIVVVGLYFLFQDEINSAAMKMIPAGKAAGAAAKALA | defense response to bacterium disruption by virus of host cell wall peptidoglycan during virus entry disruption of host cell envelope during viral entry killing of cells of another organism peptidoglycan metabolic process membrane; viral inner membrane; virion membrane lysozyme activity lytic transglycosylase activity ... |
FtsZ-dependent cytokinesis peptidoglycan biosynthetic process regulation of cell shape | plasma membrane | DNA binding | Escherichia coli | Cell inner membrane Cell membrane Cell shape DNA-binding Membrane Reference proteome Signal-anchor Transmembrane Transmembrane helix | MNTEATHDQN | MNTEATHDQNEALTTGARLRNAREQLGLSQQAVAERLCLKVSTVRDIEEDKAPADLASTFLRGYIRSYARLVHIPEEELLPGLEKQAPLRAAKVAPMQSFSLGKRRKKRDGWLMTFTWLVLFVVIGLSGAWWWQDRKAQQEEITTMADQSSAELSSNSEQGQSVPLNTSTTTDPATTSTPPASVDTTATNTQTPAVTAPAPAVDPQQNAVVSPSQANVDTAATPAPTAATTPDGAAPLPTDQAGVTTPVADPNALVMNFTADCWLEVTDATGKKLFSGMQRKDGNLNLTGQAPYKLKIGAPAAVQIQYQGKPVDLSRFIR... | FtsZ-dependent cytokinesis peptidoglycan biosynthetic process regulation of cell shape plasma membrane DNA binding Escherichia coli Cell inner membrane Cell membrane Cell shape DNA-binding Membrane Reference proteome Signal-anchor Transmembrane Transmembrane helix MNTEATHDQN MNTEATHDQNEALTTGARLRNAREQLGLSQQAVAERLCLKVSTV... |
extracellular matrix disassembly proteolysis | extracellular space; mast cell granule | identical protein binding peptidase activity serine-type endopeptidase activity | Rattus norvegicus | Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Secreted Serine protease Signal Zymogen | MLKLLLLTLP | MLKLLLLTLPLLSSLVHAAPSLAMPREGIVGGQEASGNKWPWQVSLRVNDTYWMHFCGGSLIHPQWVLTAAHCVGPNKADPNKLRVQLRKQYLYYHDHLLTVSQIISHPDFYIAQDGADIALLKLTNPVNITSNVHTVSLPPASETFPSGTLCWVTGWGNINNDVSLPPPFPLEEVQVPIVENRLCDLKYHKGLNTGDNVHIVRDDMLCAGNEGHDSCQGDSGGPLVCKVEDTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIYRYVPKYF | extracellular matrix disassembly proteolysis extracellular space; mast cell granule identical protein binding peptidase activity serine-type endopeptidase activity Rattus norvegicus Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Secreted Serine protease Signal Zymogen MLKLLL... |
metabolic process | mitochondrial matrix | malate dehydrogenase (decarboxylating) (NAD+) activity metal ion binding NAD binding oxaloacetate decarboxylase activity | Ascaris suum | 3D-structure Allosteric enzyme Metal-binding Mitochondrion NAD Oxidoreductase Transit peptide | PRVRSFIAHQ | PRVRSFIAHQSGITSVIRRSPDIAHRMVRSLSVSSQRNKSVAHHEDVYSHNLPPMDEKEMALYKLYRPERVTPKKRSAELLKEPRLNKGMGFSLYERQYLGLHGLLPPAFMTQEQQAYRVITKLREQPNDLARYIQLDGLQDRNEKLFYRVVCDHVKELMPIVYTPTVGLACQNFGYIYRKPKGLYITINDNSVSKIYQILSNWHEEDVRAIVVTDGERILGLGDLGAYGIGIPVGKLALYVALGGVQPKWCLPVLLDVGTNNMDLLNDPFYIGLRHKRVRGKDYDTLLDNFMKACTKKYGQKTLIQFEDFANPNAFRLL... | metabolic process mitochondrial matrix malate dehydrogenase (decarboxylating) (NAD+) activity metal ion binding NAD binding oxaloacetate decarboxylase activity Ascaris suum 3D-structure Allosteric enzyme Metal-binding Mitochondrion NAD Oxidoreductase Transit peptide PRVRSFIAHQ PRVRSFIAHQSGITSVIRRSPDIAHRMVRSLSVSSQRNKSV... |
intracellular signal transduction negative regulation of hippo signaling negative regulation of protein localization to nucleus peptidyl-serine autophosphorylation peptidyl-serine phosphorylation positive regulation of protein binding protein phosphorylation | cytoplasm; cytosol; dendrite; extracellular exosome; plasma membrane | ATP binding protein serine kinase activity protein serine/threonine kinase activity tau protein binding tau-protein kinase activity | Homo sapiens | 3D-structure Alternative splicing ATP-binding Cell membrane Cell projection Cytoplasm Disease variant Kinase Membrane Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MSTRTPLPTV | MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAGHEEDELKPFV... | intracellular signal transduction negative regulation of hippo signaling negative regulation of protein localization to nucleus peptidyl-serine autophosphorylation peptidyl-serine phosphorylation positive regulation of protein binding protein phosphorylation cytoplasm; cytosol; dendrite; extracellular exosome; plasma m... |
endosomal lumen acidification Golgi lumen acidification intracellular pH reduction lysosomal lumen acidification positive regulation of Wnt signaling pathway proton transmembrane transport regulation of macroautophagy vacuolar acidification | azurophil granule membrane; clathrin-coated vesicle membrane; endosome membrane; extracellular exosome; ficolin-1-rich granule membrane; focal adhesion; Golgi membrane; lysosomal membrane; membrane; phagocytic vesicle membrane; plasma membrane; proton-transporting V-type ATPase complex; synaptic vesicle membrane; terti... | proton-transporting ATP synthase activity, rotational mechanism proton-transporting ATPase activity, rotational mechanism ubiquitin protein ligase binding | Homo sapiens | 3D-structure Cytoplasmic vesicle Host-virus interaction Hydrogen ion transport Ion transport Membrane Reference proteome Synapse Transmembrane Transmembrane helix Transport Ubl conjugation | MSESKSGPEY | MSESKSGPEYASFFAVMGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPEQIMKSIIPVVMAGIIAIYGLVVAVLIANSLNDDISLYKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK | endosomal lumen acidification Golgi lumen acidification intracellular pH reduction lysosomal lumen acidification positive regulation of Wnt signaling pathway proton transmembrane transport regulation of macroautophagy vacuolar acidification azurophil granule membrane; clathrin-coated vesicle membrane; endosome membrane... |
negative regulation of floral organ abscission phosphorylation | nucleus; plasma membrane | ATP binding protein serine kinase activity protein serine/threonine kinase activity | Arabidopsis thaliana | Alternative splicing ATP-binding Cell membrane Kinase Lipoprotein Membrane Myristate Nucleotide-binding Nucleus Palmitate Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MGACISFFSS | MGACISFFSSSSPSKTGLHSHATTNNHSNGTEFSSTTGATTNSSVGQQSQFSDISTGIISDSGKLLESPNLKVYNFLDLKTATKNFKPDSMLGQGGFGKVYRGWVDATTLAPSRVGSGMIVAIKRLNSESVQGFAEWRSEVNFLGMLSHRNLVKLLGYCREDKELLLVYEFMPKGSLESHLFRRNDPFPWDLRIKIVIGAARGLAFLHSLQREVIYRDFKASNILLDSNYDAKLSDFGLAKLGPADEKSHVTTRIMGTYGYAAPEYMATGHLYVKSDVFAFGVVLLEIMTGLTAHNTKRPRGQESLVDWLRPELSNKHRV... | negative regulation of floral organ abscission phosphorylation nucleus; plasma membrane ATP binding protein serine kinase activity protein serine/threonine kinase activity Arabidopsis thaliana Alternative splicing ATP-binding Cell membrane Kinase Lipoprotein Membrane Myristate Nucleotide-binding Nucleus Palmitate Phosp... |
viral budding via host ESCRT complex | host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid | RNA binding structural constituent of virion zinc ion binding | Cas-Br-E murine leukemia virus | Alternative initiation Capsid protein Coiled coil Host cell membrane Host cytoplasm Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Phosphoprotein RNA-binding Ubl conjugation Viral budding Viral budding via the host ESCRT complexes Viral matrix protein Viral nucleoprotein... | MGQTVTTPLS | MGQTVTTPLSLTLDHWKDVERTAHNQSVDVKKRRWVTFCSVEWPTFNVGWPQDGTFNRDIITQVKIKVFSPGPHGHPDQVPYIVTWEALAFDPPPWVKPFVHPKPPLPPSAPSLLPEPPLSTSPRSSLYPALTPSLGAKPKPQVLPDSGGPLIDLLTEDPPPYRDPGPPPSDRDRDDGEAAPAGEAPDPSPMASRLRGRRELPVADSTTSQAFPLRSGGNGQLQYWPFSSSDLYNWKNNNPSFSEDPGKLTALIESVLLTHQPTWDDCQQLLGTLLTGEEKQRVLLEARKAVRGEDGRPTQLPNEINDAFPLERPDWDYN... | viral budding via host ESCRT complex host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid RNA binding structural constituent of virion zinc ion binding Cas-Br-E murine leukemia virusAlternative initiation Capsid protein Coiled coil Host cell membrane Host cytoplasm Host endosome Host membra... |
cellular detoxification of aldehyde fructosamine catabolic process gamma-aminobutyric acid biosynthetic process retinoid metabolic process retinol metabolic process | axon; cytosol; synapse | 3-deoxyglucosone dehydrogenase activity aldehyde dehydrogenase (NAD+) activity aminobutyraldehyde dehydrogenase activity benzaldehyde dehydrogenase (NAD+) activity glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity retinal dehydrogenase activity | Gallus gallus | Cell projection Cytoplasm Lipid metabolism NAD Oxidoreductase Reference proteome | MKKQGSPSNP | MKKQGSPSNPAPVLPALPEPLKDLKIKYTKIFINNEWHDSVSGKKFEVFNPANEEKICEVAEGDKADIDKAVKAARKAFELGSPWRTMDASERGRLLNKLADLVERDRLTLATMEAIDGGKLFSTAYLMDLGACIKTIRYCAGWADKIHGRTVPMDGNFFTFTRHEPVGVCGQIIPWNFPLVMFIWKIAPALCCGNTVVVKPAEQTPLSALYMGSLIKEAGFPPGVVNIVPGFGPTAGAAISHHMDIDKVSFTGSTEVGKLIKEAAGKTNLKRVTLELGGKSPNIIFADADLDEAAEFAHIGLFYHQGQCCIAGSRIFVE... | cellular detoxification of aldehyde fructosamine catabolic process gamma-aminobutyric acid biosynthetic process retinoid metabolic process retinol metabolic process axon; cytosol; synapse 3-deoxyglucosone dehydrogenase activity aldehyde dehydrogenase (NAD+) activity aminobutyraldehyde dehydrogenase activity benzaldehyd... |
lipid droplet formation mitochondrial protein catabolic process phosphatidylethanolamine biosynthetic process protein autoprocessing regulation of mitochondrion organization | cytosol; Golgi apparatus; lipid droplet; mitochondrial inner membrane; mitochondrion; nucleus | phosphatidylserine decarboxylase activity | Cricetulus griseus | Cytoplasm Decarboxylase Lipid biosynthesis Lipid droplet Lipid metabolism Lyase Membrane Mitochondrion Mitochondrion inner membrane Phospholipid biosynthesis Phospholipid metabolism Pyruvate Transit peptide Transmembrane Transmembrane helix Zymogen | MAASVCRPYV | MAASVCRPYVRSLPGVMPWRSSSCHYEYTAMHHFLGSFQKLPFEPFNTGARKIHTAPVRSLFLLRPVPILLATGGGYAGYRQYEKYRDQKLEKLGLEIPPKLASHWEVALYKSVPTRLLSRAWGRLNQVELPYWLRRPVYSLYIWTFGVNMTEAAVEDLHHYRNLSEFFRRKLKPQARPVCGLHSVISPSDGKILTFGQVKNCEVEQVKGVTYSLESFLGPRTYTEDLSFPPASSRDSFRNQLVTREGNELYHCVIYLAPGDYHCFHSPTDWTVSHRRHFPGSLMSVNPGMARWIKELFCHNERVVLSGDWKHGFFSLTA... | lipid droplet formation mitochondrial protein catabolic process phosphatidylethanolamine biosynthetic process protein autoprocessing regulation of mitochondrion organization cytosol; Golgi apparatus; lipid droplet; mitochondrial inner membrane; mitochondrion; nucleus phosphatidylserine decarboxylase activity Cricetulus... |
cellular response to oxidative stress phosphorylation signal transduction | cytoplasm | ATP binding calmodulin binding calmodulin-dependent protein kinase activity protein kinase activity protein serine kinase activity | Saccharomyces cerevisiae | ATP-binding Calmodulin-binding Kinase Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MDDKVSEKES | MDDKVSEKESSPKQTEEDSEGKMAHVQPASYVNKKKYVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSAFRAERVQDFLDECTTGEYPVKFHRPYWDSVSNKAKQFILKALNLDPSKRPTAAELLEDPWIICTELKTHNLLPGLKEGLDAR... | cellular response to oxidative stress phosphorylation signal transduction cytoplasm ATP binding calmodulin binding calmodulin-dependent protein kinase activity protein kinase activity protein serine kinase activity Saccharomyces cerevisiae ATP-binding Calmodulin-binding Kinase Nucleotide-binding Phosphoprotein Referen... |
glycogen biosynthetic process | cytoplasm; nucleus | glycogen (starch) synthase activity identical protein binding molecular function inhibitor activity | Saccharomyces cerevisiae | 3D-structure Allosteric enzyme Direct protein sequencing Glycogen biosynthesis Glycosyltransferase Phosphoprotein Reference proteome Transferase | MSRDLQNHLL | MSRDLQNHLLFETATEVANRVGGIYSVLKSKAPITVAQYKDHYHLIGPLNKATYQNEVDILDWKKPEAFSDEMRPVQHALQTMESRGVHFVYGRWLIEGAPKVILFDLDSVRGYSNEWKGDLWSLVGIPSPENDFETNDAILLGYTVAWFLGEVAHLDSQHAIVAHFHEWLAGVALPLCRKRRIDVVTIFTTHATLLGRYLCASGSFDFYNCLESVDVDHEAGRFGIYHRYCIERAAAHSADVFTTVSQITAFEAEHLLKRKPDGILPNGLNVIKFQAFHEFQNLHALKKEKINDFVRGHFHGCFDFDLDNTLYFFIAGR... | glycogen biosynthetic process cytoplasm; nucleus glycogen (starch) synthase activity identical protein binding molecular function inhibitor activity Saccharomyces cerevisiae 3D-structure Allosteric enzyme Direct protein sequencing Glycogen biosynthesis Glycosyltransferase Phosphoprotein Reference proteome Transferase ... |
maturation of SSU-rRNA ribosomal small subunit assembly rRNA processing | mitochondrion; nuclear envelope; nucleolus; nucleus; small-subunit processome | mRNA binding nuclear localization sequence binding RNA binding single-stranded telomeric DNA binding | Saccharomyces cerevisiae | DNA-binding Methylation Nucleus Phosphoprotein Reference proteome Repeat RNA-binding rRNA processing Stress response | MAKTTKVKGN | MAKTTKVKGNKKEVKASKQAKEEKAKAVSSSSSESSSSSSSSSESESESESESESSSSSSSSDSESSSSSSSDSESEAETKKEESKDSSSSSSDSSSDEEEEEEKEETKKEESKESSSSDSSSSSSSDSESEKEESNDKKRKSEDAEEEEDEESSNKKQKNEETEEPATIFVGRLSWSIDDEWLKKEFEHIGGVIGARVIYERGTDRSRGYGYVDFENKSYAEKAIQEMQGKEIDGRPINCDMSTSKPAGNNDRAKKFGDTPSEPSDTLFLGNLSFNADRDAIFELFAKHGEVVSVRIPTHPETEQPKGFGYVQFSNMED... | maturation of SSU-rRNA ribosomal small subunit assembly rRNA processing mitochondrion; nuclear envelope; nucleolus; nucleus; small-subunit processome mRNA binding nuclear localization sequence binding RNA binding single-stranded telomeric DNA binding Saccharomyces cerevisiae DNA-binding Methylation Nucleus Phosphoprot... |
apoptotic cell clearance arachidonic acid metabolic process bone mineralization cellular response to calcium ion cellular response to interleukin-13 fatty acid oxidation hepoxilin biosynthetic process linoleic acid metabolic process lipid oxidation lipoxin A4 biosynthetic process lipoxygenase pathway negative regulatio... | cytoplasmic side of plasma membrane; cytosol; lipid droplet; membrane; plasma membrane | arachidonate 12(S)-lipoxygenase activity arachidonate 15-lipoxygenase activity iron ion binding linoleate 13S-lipoxygenase activity phosphatidylinositol-4,5-bisphosphate binding | Bos taurus | Calcium Cell membrane Cytoplasm Dioxygenase Fatty acid metabolism Iron Lipid droplet Lipid metabolism Lipid-binding Membrane Metal-binding Oxidoreductase Reference proteome | MGLYRVRVST | MGLYRVRVSTGSSFCAGSNNQVHLWLVGEHGEAALGWRLRPARGKEVEFQVDVSEYLGRLLFVKLRKRHLLSDDAWFCNWISVQGPGASGNEFRFPCYRWVEGDGILSLPEGTGRTVVDDPQGLFKKHREEELAERRKLYRWGNWKDGLILNIAGATINDLPVDERFLEDKRIDFEASLTKGLADLAIKDSLNILTCWKSLDDFNRIFWCGQSKLAERVRDSWKEDALFGYQFLNGTNPMLLRRSVRLPARLEFPPGMGELQAELEKELQQGTLFEADFSLLDGIKANVILCTQQYVAAPLVMLKLQPDGKLLPMAIQLQ... | apoptotic cell clearance arachidonic acid metabolic process bone mineralization cellular response to calcium ion cellular response to interleukin-13 fatty acid oxidation hepoxilin biosynthetic process linoleic acid metabolic process lipid oxidation lipoxin A4 biosynthetic process lipoxygenase pathway negative regulatio... |
behavioral fear response cell adhesion endothelial cell migration glucagon processing locomotory exploration behavior membrane fusion negative regulation of extracellular matrix disassembly negative regulation of neutrophil chemotaxis peptide hormone processing positive regulation of cell population proliferation prote... | apical plasma membrane; cell surface; endocytic vesicle; extracellular exosome; extracellular region; focal adhesion; intercellular canaliculus; lamellipodium; lamellipodium membrane; lysosomal membrane; membrane; membrane raft; plasma membrane | aminopeptidase activity chemorepellent activity dipeptidyl-peptidase activity identical protein binding protease binding protein homodimerization activity serine-type endopeptidase activity serine-type peptidase activity signaling receptor binding virus receptor activity | Homo sapiens | 3D-structure Aminopeptidase Cell adhesion Cell junction Cell membrane Cell projection Direct protein sequencing Disulfide bond Glycoprotein Host-virus interaction Hydrolase Membrane Protease Receptor Reference proteome Secreted Serine protease Signal-anchor Transmembrane Transmembrane helix | MKTPWKVLLG | MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADSRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQ... | behavioral fear response cell adhesion endothelial cell migration glucagon processing locomotory exploration behavior membrane fusion negative regulation of extracellular matrix disassembly negative regulation of neutrophil chemotaxis peptide hormone processing positive regulation of cell population proliferation prote... |
photosynthesis, light harvesting | chloroplast thylakoid membrane; photosystem I; photosystem II | chlorophyll binding metal ion binding | Pisum sativum | 3D-structure Acetylation Chlorophyll Chloroplast Chromophore Direct protein sequencing Magnesium Membrane Metal-binding Phosphoprotein Photosynthesis Photosystem I Photosystem II Plastid Thylakoid Transit peptide Transmembrane Transmembrane helix | MAASSMALSS | MAASSMALSSPTLTGKPVETSANPSSQELGGARFTMRKSATTKKVASSGSPWYGPDRVKYLGPFSGESPSYLTGEFPGDYGWDTAGLSADPETFSKNRELEVIHSRWAMLGALGCVFPELLSRNGVKFGEAVWFKAGSQIFSEGGLDYLGNPSLVHAQSILAIWATQVILMGAVEGYRIAGGPLGEVVDPLYPGGSFDPLGLADDPEAFAELKVKELKNGRLAMFSMFGFFVQAIVTGKGPLENLADHLSDPVNNNAWSYATNFVPGK | photosynthesis, light harvesting chloroplast thylakoid membrane; photosystem I; photosystem II chlorophyll binding metal ion binding Pisum sativum 3D-structure Acetylation Chlorophyll Chloroplast Chromophore Direct protein sequencing Magnesium Membrane Metal-binding Phosphoprotein Photosynthesis Photosystem I Photosys... |
glycerol-3-phosphate transmembrane transport phosphate ion transport polyphosphate metabolic process regulation of phosphate transmembrane transport | fungal-type vacuole membrane; vacuole-mitochondrion membrane contact site | glycerol-3-phosphate transmembrane transporter activity inorganic phosphate transmembrane transporter activity | Saccharomyces cerevisiae | Membrane Phosphate transport Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport Ubl conjugation Vacuole | MKFSHSLQFN | MKFSHSLQFNSVPEWSTKYLAYSQLKKLIYSLQKDKLYSNNKHHVVEPHDANDENLPLLADASPDDQFYISKFVAALNQELKKIDKFYISQETGLIANYNELKDDVMELENTNKATQLFNQQQQHQLQSVARNRKSKSQQRQRRFSSVSSTDSNPSLTDMSIDSAPVIHTQVSNTTNNGNSMQNLASASVSLSNSNPVYLSPFTQHRLSLKKRLISIYTQLSELKDFIELNQTGFSKICKKFDKSLNTNLKQNYLNYIKFHSHVFNPATINRIQHHITETILTYASLNKGTRRPSNTFNLDADRINNDENSSGNEEDEDG... | glycerol-3-phosphate transmembrane transport phosphate ion transport polyphosphate metabolic process regulation of phosphate transmembrane transport fungal-type vacuole membrane; vacuole-mitochondrion membrane contact site glycerol-3-phosphate transmembrane transporter activity inorganic phosphate transmembrane transpo... |
CTP salvage phosphorylation pyrimidine-containing compound salvage UMP salvage | cytoplasm; nucleus | ATP binding cytidine kinase activity uridine kinase activity | Saccharomyces cerevisiae | ATP-binding Cytoplasm Kinase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Transferase | MSHRIAPSKE | MSHRIAPSKERSSSFISILDDETRDTLKANAVMDGEVDVKKTKGKSSRYIPPWTTPYIIGIGGASGSGKTSVAAKIVSSINVPWTVLISLDNFYNPLGPEDRARAFKNEYDFDEPNAINLDLAYKCILNLKEGKRTNIPVYSFVHHNRVPDKNIVIYGASVVVIEGIYALYDRRLLDLMDLKIYVDADLDVCLARRLSRDIVSRGRDLDGCIQQWEKFVKPNAVKFVKPTMKNADAIIPSMSDNATAVNLIINHIKSKLELKSNEHLRELIKLGSSPSQDVLNRNIIHELPPTNQVLSLHTMLLNKNLNCADFVFYFDRL... | CTP salvage phosphorylation pyrimidine-containing compound salvage UMP salvage cytoplasm; nucleus ATP binding cytidine kinase activity uridine kinase activity Saccharomyces cerevisiae ATP-binding Cytoplasm Kinase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Transferase MSHRIAPSKE MSHRIAPSKERSSSFISILDDE... |
photosynthesis, light harvesting in photosystem I response to cold response to high light intensity response to low light intensity stimulus | chloroplast; chloroplast envelope; chloroplast thylakoid; chloroplast thylakoid membrane; cytosol; photosystem I; thylakoid | chlorophyll binding metal ion binding mRNA binding protein domain specific binding | Arabidopsis thaliana | 3D-structure Chlorophyll Chloroplast Chromophore Magnesium Membrane Metal-binding Phosphoprotein Photosynthesis Photosystem I Plastid Reference proteome Thylakoid Transit peptide Transmembrane Transmembrane helix | MATVTTHASA | MATVTTHASASIFRPCTSKPRFLTGSSGRLNRDLSFTSIGSSAKTSSFKVEAKKGEWLPGLASPDYLTGSLAGDNGFDPLGLAEDPENLKWFVQAELVNGRWAMLGVAGMLLPEVFTKIGIINVPEWYDAGKEQYFASSSTLFVIEFILFHYVEIRRWQDIKNPGSVNQDPIFKQYSLPKGEVGYPGGIFNPLNFAPTQEAKEKELANGRLAMLAFLGFVVQHNVTGKGPFENLLQHLSDPWHNTIVQTFN | photosynthesis, light harvesting in photosystem I response to cold response to high light intensity response to low light intensity stimulus chloroplast; chloroplast envelope; chloroplast thylakoid; chloroplast thylakoid membrane; cytosol; photosystem I; thylakoid chlorophyll binding metal ion binding mRNA binding prot... |
cell differentiation cellular response to oxidative stress embryonic placenta development negative regulation of inflammatory response positive regulation of endothelial cell proliferation positive regulation of erythrocyte differentiation positive regulation of glycolytic process positive regulation of hormone biosynt... | aryl hydrocarbon receptor complex; chromatin; cytoplasm; nuclear aryl hydrocarbon receptor complex; nuclear body; nucleoplasm; nucleus; RNA polymerase II transcription regulator complex | aryl hydrocarbon receptor binding cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific nuclear receptor activity protein heterodimerization activity protein homodimerization activity RNA polymerase II cis-regu... | Homo sapiens | 3D-structure Acetylation Activator Alternative splicing Direct protein sequencing DNA-binding Isopeptide bond Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation Ubl conjugation | MAATTANPEM | MAATTANPEMTSDVPSLGPAIASGNSGPGIQGGGAIVQRAIKRRPGLDFDDDGEGNSKFLRCDDDQMSNDKERFARSDDEQSSADKERLARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMKSLRGTGNTSTDGSYKPSFLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPVLNQPQSEWFGSTLYDQVHPDDVDKLREQLSTSENALTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGSSSVDPVSVNRLSFVRNRCRNGLGSVKDGEPHFVVVHCTGYIKAWPPAGV... | cell differentiation cellular response to oxidative stress embryonic placenta development negative regulation of inflammatory response positive regulation of endothelial cell proliferation positive regulation of erythrocyte differentiation positive regulation of glycolytic process positive regulation of hormone biosynt... |
cellular response to dithiothreitol cellular response to mycotoxin cellular response to UV-A cellular response to xenobiotic stimulus ceramide biosynthetic process negative regulation of telomerase activity positive regulation of mitophagy sphingolipid biosynthetic process | endoplasmic reticulum; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; membrane | sphingosine N-acyltransferase activity | Homo sapiens | Acetylation Alternative splicing Disease variant Endoplasmic reticulum Epilepsy Lipid biosynthesis Lipid metabolism Membrane Neurodegeneration Reference proteome Transferase Transmembrane Transmembrane helix | MAAAGPAAGP | MAAAGPAAGPTGPEPMPSYAQLVQRGWGSALAAARGCTDCGWGLARRGLAEHAHLAPPELLLLALGALGWTALRSAATARLFRPLAKRCCLQPRDAAKMPESAWKFLFYLGSWSYSAYLLFGTDYPFFHDPPSVFYDWTPGMAVPRDIAAAYLLQGSFYGHSIYATLYMDTWRKDSVVMLLHHVVTLILIVSSYAFRYHNVGILVLFLHDISDVQLEFTKLNIYFKSRGGSYHRLHALAADLGCLSFGFSWFWFRLYWFPLKVLYATSHCSLRTVPDIPFYFFFNALLLLLTLMNLYWFLYIVAFAAKVLTGQVHELKDL... | cellular response to dithiothreitol cellular response to mycotoxin cellular response to UV-A cellular response to xenobiotic stimulus ceramide biosynthetic process negative regulation of telomerase activity positive regulation of mitophagy sphingolipid biosynthetic process endoplasmic reticulum; endoplasmic reticulum m... |
brain development cellular response to dithiothreitol cellular response to mycotoxin cellular response to UV-A cellular response to xenobiotic stimulus ceramide biosynthetic process negative regulation of glucose import positive regulation of mitophagy sphingolipid biosynthetic process | endoplasmic reticulum; endoplasmic reticulum membrane; intracellular membrane-bounded organelle | N-acyltransferase activity sphingosine N-acyltransferase activity | Mus musculus | Acetylation Endoplasmic reticulum Lipid biosynthesis Lipid metabolism Membrane Reference proteome Transferase Transmembrane Transmembrane helix | MAAAAATPRL | MAAAAATPRLEAPEPMPSYAQMLQRSWASALAAAQGCGDCGWGLARRGLAEHAHLAAPELLLAVLCALGWTALRWAATTHIFRPLAKRCRLQPRDAARLPESAWKLLFYLACWSYCAYLLLGTSYPFFHDPPSVFYDWRSGMAVPWDIAVAYLLQGSFYCHSIYATVYMDSWRKDSVVMLVHHVVTLLLIASSYAFRYHNVGLLVFFLHDVSDVQLEFTKLNIYFKARGGAYHRLHGLVANLGCLSFCFCWFWFRLYWFPLKVLYATCHCSLQSVPDIPYYFFFNILLLLLMVMNIYWFLYIVAFAAKVLTGQMRELEDL... | brain development cellular response to dithiothreitol cellular response to mycotoxin cellular response to UV-A cellular response to xenobiotic stimulus ceramide biosynthetic process negative regulation of glucose import positive regulation of mitophagy sphingolipid biosynthetic process endoplasmic reticulum; endoplasmi... |
B cell differentiation B cell proliferation CD40 signaling pathway dendritic cell differentiation inflammatory response integrin-mediated signaling pathway isotype switching negative regulation of apoptotic process platelet activation positive regulation of B cell proliferation positive regulation of dendritic cell dif... | cell body; cell projection; cell surface; external side of plasma membrane; extracellular space; Golgi apparatus; plasma membrane | CD40 receptor binding cytokine activity integrin binding protein serine/threonine kinase activator activity tumor necrosis factor receptor binding | Mus musculus | Cell membrane Cytokine Disulfide bond Glycoprotein Membrane Reference proteome Secreted Signal-anchor Transmembrane Transmembrane helix | MIETYSQPSP | MIETYSQPSPRSVATGLPASMKIFMYLLTVFLITQMIGSVLFAVYLHRRLDKVEEEVNLHEDFVFIKKLKRCNKGEGSLSLLNCEEMRRQFEDLVKDITLNKEEKKENSFEMQRGDEDPQIAAHVVSEANSNAASVLQWAKKGYYTMKSNLVMLENGKQLTVKREGLYYVYTQVTFCSNREPSSQRPFIVGLWLKPSSGSERILLKAANTHSSSQLCEQQSVHLGGVFELQAGASVFVNVTEASQVIHRVGFSSFGLLKL | B cell differentiation B cell proliferation CD40 signaling pathway dendritic cell differentiation inflammatory response integrin-mediated signaling pathway isotype switching negative regulation of apoptotic process platelet activation positive regulation of B cell proliferation positive regulation of dendritic cell dif... |
acetate catabolic process acetyl-CoA biosynthetic process acetyl-CoA biosynthetic process from acetate chemotaxis peptidyl-lysine acetylation post-translational protein acetylation | cytosol | acetate-CoA ligase activity AMP binding ATP binding metal ion binding propionate-CoA ligase activity protein lysine deacetylase activity | Escherichia coli | Acetylation ATP-binding Ligase Magnesium Metal-binding Nucleotide-binding Reference proteome | MSQIHKHTIP | MSQIHKHTIPANIADRCLINPQQYEAMYQQSINVPDTFWGEQGKILDWIKPYQKVKNTSFAPGNVSIKWYEDGTLNLAANCLDRHLQENGDRTAIIWEGDDASQSKHISYKELHRDVCRFANTLLELGIKKGDVVAIYMPMVPEAAVAMLACARIGAVHSVIFGGFSPEAVAGRIIDSNSRLVITSDEGVRAGRSIPLKKNVDDALKNPNVTSVEHVVVLKRTGGKIDWQEGRDLWWHDLVEQASDQHQAEEMNAEDPLFILYTSGSTGKPKGVLHTTGGYLVYAALTFKYVFDYHPGDIYWCTADVGWVTGHSYLLYGP... | acetate catabolic process acetyl-CoA biosynthetic process acetyl-CoA biosynthetic process from acetate chemotaxis peptidyl-lysine acetylation post-translational protein acetylation cytosol acetate-CoA ligase activity AMP binding ATP binding metal ion binding propionate-CoA ligase activity protein lysine deacetylase act... |
cell cycle cell division dephosphorylation negative regulation of p38MAPK cascade regulation of p38MAPK cascade | cytoplasm; cytosol; nucleus; protein aggregate center | MAP kinase tyrosine phosphatase activity protein tyrosine phosphatase activity | Schizosaccharomyces pombe | Cell cycle Cell division Cytoplasm Hydrolase Mitosis Phosphoprotein Protein phosphatase Reference proteome | MNFSNGSKSS | MNFSNGSKSSTFTIAPSGSCIALPPQRGVATSKYAVHASCLQEYLDKEAWKDDTLIIDLRPVSEFSKSRIKGSVNLSLPATLIKRPAFSVARIISNLHDVDDKRDFQNWQEFSSILVCVPAWIANYVTNAEVIGEKFRKESYSGDFGILDLDYSKVSGKYPSVIDNSPVKSKLGALPSARPRLSYSAAQTAPISLSSEGSDYFSRPPPTPNVAGLSLNNFFCPLPENKDNKSSPFGSATVQTPCLHSVPDAFTNPDVATLYQKFLRLQSLEHQRLVSCSDRNSQWSTVDSLSNTSYKKNRYTDIVPYNCTRVHLKRTSPS... | cell cycle cell division dephosphorylation negative regulation of p38MAPK cascade regulation of p38MAPK cascade cytoplasm; cytosol; nucleus; protein aggregate center MAP kinase tyrosine phosphatase activity protein tyrosine phosphatase activity Schizosaccharomyces pombe Cell cycle Cell division Cytoplasm Hydrolase Mit... |
cell motility immune system process negative regulation of cell cycle negative regulation of inflammatory response PML body organization positive regulation of angiogenesis positive regulation of blood vessel endothelial cell migration positive regulation of cell migration positive regulation of cell population prolife... | cytoplasm; nucleoplasm; nucleus; transcription regulator complex | DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor binding histone acetyltransferase binding identical protein binding nuclear receptor coact... | Mus musculus | 3D-structure Acetylation Alternative splicing Cytoplasm DNA-binding Immunity Isopeptide bond Nucleus Phosphoprotein Proto-oncogene Reference proteome Transcription Transcription regulation Ubl conjugation | MKAAVDLKPT | MKAAVDLKPTLTIIKTEKVDLELFPSPDMECADVPLLTPSSKEMMSQALKATFSGFTKEQQRLGIPKDPRQWTETHVRDWVMWAVNEFSLKGVDFQKFCMSGAALCALGKECFLELAPDFVGDILWEHLEILQKEDVKPYQVNGANPTYPESCYTSDYFISYGIEHAQCVPPSEFSEPSFITESYQTLHPISSEELLSLKYENDYPSVILQDPLQTDTLQTDYFAIKQEVLTPDNMCLGRASRGKLGGQDSFESVESYDSCDRLTQSWSSQSSFNSLQRVPSYDSFDYEDYPAALPNHKPKGTFKDYVRDRADLNKDKPV... | cell motility immune system process negative regulation of cell cycle negative regulation of inflammatory response PML body organization positive regulation of angiogenesis positive regulation of blood vessel endothelial cell migration positive regulation of cell migration positive regulation of cell population prolife... |
G protein-coupled receptor signaling pathway negative regulation of MAPK cascade pheromone response MAPK cascade pheromone-dependent signal transduction involved in conjugation with cellular fusion positive regulation of conjugation with cellular fusion sporulation resulting in formation of a cellular spore | cortical dynamic polarity patch; cytosol; heterotrimeric G-protein complex; plasma membrane | G protein-coupled receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity metal ion binding | Schizosaccharomyces pombe | GTP-binding Lipoprotein Magnesium Metal-binding Myristate Nucleotide-binding Palmitate Pheromone response Reference proteome Sporulation Transducer | MGCMSSKYAD | MGCMSSKYADTSGGEVIQKKLSDTQTSNSSTTGSQNARVPVLENWLNIVLRGKPQNVESSGVRVKGNSTSGGNDIKVLLLGAGDSGKTTIMKQMRLLYSPGFSQVVRKQYRVMIFENIISSLCLLLEAMDNSNVSLLPENEKYRAVILRKHTSQPNEPFSPEIYEAVHALTLDTKLRTVQSCGTNLSLLDNFYYYQDHIDRIFDPQYIPSDQDILHCRIKTTGISEETFLLNRHHYRFFDVGGQRSERRKWIHCFENVTALLFLVSLAGYDQCLVEDNSGNQMQEALLLWDSICNSSWFSESAMILFLNKLDLFKRKVHI... | G protein-coupled receptor signaling pathway negative regulation of MAPK cascade pheromone response MAPK cascade pheromone-dependent signal transduction involved in conjugation with cellular fusion positive regulation of conjugation with cellular fusion sporulation resulting in formation of a cellular spore cortical dy... |
cellular response to type I interferon defense response to virus endosomal transport negative regulation of intracellular transport of viral material negative regulation of viral genome replication | cytoplasm; endoplasmic reticulum membrane; membrane; microtubule; nucleus; perinuclear region of cytoplasm | GTP binding GTPase activity microtubule binding | Sus scrofa | Acetylation Antiviral defense Cytoplasm Endoplasmic reticulum GTP-binding Immunity Innate immunity Membrane Nucleotide-binding Reference proteome Ubl conjugation | MVYSSCESKE | MVYSSCESKEPDSVSASNHLLLNGNDELVEKSHKTGPENNLYSQYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEEDEWKGKVSYRDSEIELSDASQVEKEVSAAQIAIAGEGVGISHELISLEVSSPHVPDLTLIDLPGITRVAVGNQPYDIEYQIKSLIKKYICKQETINLVVVPCNVDIATTEALRMAQEVDPEGDRTIGILTKPDLVDKGTEDKIVDVARNLVFHLKKGYMIVKCRGQQDIQEQLSLAKALQKEQAFFENHAHFRDLLEEGRAT... | cellular response to type I interferon defense response to virus endosomal transport negative regulation of intracellular transport of viral material negative regulation of viral genome replication cytoplasm; endoplasmic reticulum membrane; membrane; microtubule; nucleus; perinuclear region of cytoplasm GTP binding GTP... |
carbohydrate phosphorylation fructose 6-phosphate metabolic process glucose 6-phosphate metabolic process glucose metabolic process glycolytic process inflammatory response innate immune response intracellular glucose homeostasis mannose metabolic process | cytosol; mitochondrial outer membrane; mitochondrion | ATP binding fructokinase activity glucokinase activity glucosamine kinase activity glucose binding mannokinase activity | Bos taurus | Acetylation Allosteric enzyme ATP-binding Cytoplasm Glycolysis Immunity Inflammatory response Innate immunity Kinase Membrane Mitochondrion Mitochondrion outer membrane Nucleotide-binding Phosphoprotein Reference proteome Repeat Transferase | MIAAQLLAYY | MIAAQLLAYYFTELKDDQVKKIDKYLYAMRLSDETLLDIMNRFKKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEQNRPVHMESEVYDTPENIMHGSGSQLFDHVLECLGDFMEKKKIKDKKLPVGFTFSFPCRQSKIDQAILITWTKRFKARGAEGNYVVKLLDKAIKKRGDYDANIVAVVNDTVGTMIDCGYDDQHCEVGLIIGTGTNACYMEELRQIDFGWGDDGRMCINTEWGDLGDDGSLEDIRKEFDREFRRGSLNPGKQRFEKMVSGRYMEDVVRLVLVKMAKEGLLF... | carbohydrate phosphorylation fructose 6-phosphate metabolic process glucose 6-phosphate metabolic process glucose metabolic process glycolytic process inflammatory response innate immune response intracellular glucose homeostasis mannose metabolic process cytosol; mitochondrial outer membrane; mitochondrion ATP binding... |
blood vessel diameter maintenance cGMP biosynthetic process female pregnancy receptor guanylyl cyclase signaling pathway regulation of blood pressure | cell projection; extracellular region; perikaryon | hormone activity | Cavia porcellus | Cell projection Disulfide bond Hormone Phosphoprotein Reference proteome Secreted Vasoactive | NPMYNVVSNA | NPMYNVVSNADLVDFKNLLDHLEEKMPLEDEVVLPQVASEQNEEAGAVLSALPEVPSWPGEAGPAQREGGALGRGPWDSSDRSAPLKSKLRALLDAPRSLRRSSCFGGRMDRIGAQSSLGCNSFRYRR | blood vessel diameter maintenance cGMP biosynthetic process female pregnancy receptor guanylyl cyclase signaling pathway regulation of blood pressure cell projection; extracellular region; perikaryon hormone activity Cavia porcellus Cell projection Disulfide bond Hormone Phosphoprotein Reference proteome Secreted Vasoa... |
adenylate cyclase-modulating G protein-coupled receptor signaling pathway cell differentiation embryonic digit morphogenesis G protein-coupled receptor signaling pathway in utero embryonic development intracellular signal transduction negative regulation of vascular associated smooth muscle cell migration negative regu... | brush border membrane; cytoplasm; heterotrimeric G-protein complex; lateral plasma membrane; neuron projection; neuronal cell body | D5 dopamine receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity metal ion binding protein phosphatase 2A binding protein phosphatase regulator activity | Mus musculus | 3D-structure Cell membrane Cytoplasm GTP-binding Lipoprotein Magnesium Membrane Metal-binding Nucleotide-binding Palmitate Phosphoprotein Reference proteome Transducer | MSGVVRTLSR | MSGVVRTLSRCLLPAEAGARERRAGAARDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQHSENEKHGMFLMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKSVSIKKHFPDFKGDPH... | adenylate cyclase-modulating G protein-coupled receptor signaling pathway cell differentiation embryonic digit morphogenesis G protein-coupled receptor signaling pathway in utero embryonic development intracellular signal transduction negative regulation of vascular associated smooth muscle cell migration negative regu... |
adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway angiogenesis branching involved in blood vessel morphogenesis cell differentiation G protein-coupled receptor signaling pathway in utero embryonic development intracellular... | brush border membrane; cytoplasm; cytosol; heterotrimeric G-protein complex; melanosome; nucleus; plasma membrane | D5 dopamine receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity metal ion binding | Mus musculus | 3D-structure Cytoplasm Direct protein sequencing GTP-binding Lipoprotein Magnesium Membrane Metal-binding Nucleotide-binding Nucleus Palmitate Phosphoprotein Reference proteome Transducer | MADFLPSRSV | MADFLPSRSVLSVCFPGCVLTNGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNKNQLHGDKLMAFDTRAPMAAQGMVETRVFLQYLPAIRALWEDSGIQNAYDRRREFQLGESVKYFLDNLDKLGVPDYIPSQQDILLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRQTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQVVSIKDYFLEFEGDPHCLR... | adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway angiogenesis branching involved in blood vessel morphogenesis cell differentiation G protein-coupled receptor signaling pathway in utero embryonic development intracellular... |
adenine metabolic process AMP salvage cellular response to insulin stimulus central nervous system neuron development cerebral cortex neuron differentiation dendrite morphogenesis dopamine metabolic process dopaminergic neuron differentiation GMP catabolic process GMP salvage grooming behavior guanine salvage hypoxanth... | cytoplasm; cytosol | guanine phosphoribosyltransferase activity hypoxanthine phosphoribosyltransferase activity identical protein binding magnesium ion binding nucleotide binding | Rattus norvegicus | Acetylation Cytoplasm Direct protein sequencing Glycosyltransferase Isopeptide bond Magnesium Metal-binding Nucleotide-binding Phosphoprotein Purine salvage Reference proteome Transferase Ubl conjugation | MSTLSPSVVI | MSTLSPSVVISDDEPGYDLDLFCIPNHYAEDLEKVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVKQYSPKMVKVASLLVKRTSRSVGYRPDFVGFEIPDKFVVGYALDYNEHFRDLNHVCVISESGKAKYKA | adenine metabolic process AMP salvage cellular response to insulin stimulus central nervous system neuron development cerebral cortex neuron differentiation dendrite morphogenesis dopamine metabolic process dopaminergic neuron differentiation GMP catabolic process GMP salvage grooming behavior guanine salvage hypoxanth... |
cyclooxygenase pathway prostaglandin biosynthetic process regulation of blood pressure response to oxidative stress | cytoplasm; endoplasmic reticulum membrane; neuron projection | heme binding metal ion binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen peroxidase activity prostaglandin-endoperoxide synthase activity | Gallus gallus | Dioxygenase Disulfide bond Endoplasmic reticulum Fatty acid biosynthesis Fatty acid metabolism Glycoprotein Heme Iron Lipid biosynthesis Lipid metabolism Membrane Metal-binding Microsome Oxidoreductase Peroxidase Prostaglandin biosynthesis Prostaglandin metabolism Reference proteome Signal | MLLPCALLAA | MLLPCALLAALLAAGHAANPCCSLPCQNRGVCMTTGFDRYECDCTRTGYYGENCTTPEFFTWLKLILKPTPNTVHYILTHFKGVWNIINNISFLRDTIMRYVLTSRSHLIDSPPTYNSDYSYKSWEAYSNLSYYTRSLPPVGHDCPTPMGVKGKKELPDSKLIVEKFLLRRKFIPDPQGTNVMFTFFAQHFTHQFFKTDHKKGPGFTKAYGHGVDLNHIYGETLERQLKLRLRKDGKLKYQMIDGEMYPPTVKDTQAEMIYPPHVPEHLQFSVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWDDEQLFQTTRL... | cyclooxygenase pathway prostaglandin biosynthetic process regulation of blood pressure response to oxidative stress cytoplasm; endoplasmic reticulum membrane; neuron projection heme binding metal ion binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two at... |
cellular response to lipopolysaccharide inflammatory response macroautophagy negative regulation of protein K63-linked ubiquitination nervous system development positive regulation of dendrite extension positive regulation of neuron migration positive regulation of phospholipase A2 activity positive regulation of synap... | cytoplasm; extracellular exosome; nucleus; synapse | phospholipase A2 activator activity ubiquitin binding | Mus musculus | Acetylation Cytoplasm Developmental protein Neurogenesis Nucleus Phosphoprotein Reference proteome Repeat Synapse WD repeat | MASGASRYRL | MASGASRYRLSCSLPGHELDVRGLVCCLYPPGAFVSVSRDRTTRLWAPDSPNRGFTEMHCMSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSPMPLYILKGHKDTVCSLSSGKFGTLLSGSWDTTAKVWLNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTIKLWKAGRCERTFLGHEDCVRGLAILSETEFLSCANDASIRRWQITGECLEVYFGHTNYIYSISVFPNSKDFVTTAEDRSLRIWKHGECAQTIRLPAQSIWCCCVLENGDIVVGASDGIIRVFTESEERTASAEEIKAFERELSQA... | cellular response to lipopolysaccharide inflammatory response macroautophagy negative regulation of protein K63-linked ubiquitination nervous system development positive regulation of dendrite extension positive regulation of neuron migration positive regulation of phospholipase A2 activity positive regulation of synap... |
nitrogen compound metabolic process proteolysis involved in protein catabolic process | fungal-type vacuole; fungal-type vacuole lumen; vacuolar lumen; vacuolar membrane | carboxypeptidase activity metal ion binding metallocarboxypeptidase activity | Saccharomyces cerevisiae | Carboxypeptidase Glycoprotein Hydrolase Isopeptide bond Membrane Metal-binding Protease Reference proteome Transmembrane Transmembrane helix Ubl conjugation Vacuole Zinc | MIALPVEKAP | MIALPVEKAPRKSLWQRHRAFISGIVALIIIGTFFLTSGLHPAPPHEAKRPHHGKGPMHSPKCEKIEPLSPSFKHSVDTILHDPAFRNSSIEKLSNAVRIPTVVQDKNPNPADDPDFYKHFYELHDYFEKTFPNIHKHLKLEKVNELGLLYTWEGSDPDLKPLLLMAHQDVVPVNNETLSSWKFPPFSGHYDPETDFVWGRGSNDCKNLLIAEFEAIEQLLIDGFKPNRTIVMSLGFDEEASGTLGAASLASFLHERYGDDGIYSIIDEGEGIMEVDKDVFVATPINAEKGYVDFEVSILGHGGHSSVPPDHTTIGIASE... | nitrogen compound metabolic process proteolysis involved in protein catabolic process fungal-type vacuole; fungal-type vacuole lumen; vacuolar lumen; vacuolar membrane carboxypeptidase activity metal ion binding metallocarboxypeptidase activity Saccharomyces cerevisiae Carboxypeptidase Glycoprotein Hydrolase Isopeptid... |
aminophospholipid transport endosome to plasma membrane protein transport positive regulation of neuron projection development protein targeting to lysosome receptor-mediated endocytosis regulation of carbohydrate catabolic process sensory perception of sound | cytoplasm; endocytic vesicle membrane; lysosomal lumen; lysosomal membrane; plasma membrane | cargo receptor activity cholesterol binding enzyme binding phosphatidylcholine binding phosphatidylserine binding protein homodimerization activity protein-folding chaperone binding scavenger receptor activity | Rattus norvegicus | Direct protein sequencing Disulfide bond Glycoprotein Lipoprotein Lysosome Membrane Palmitate Receptor Reference proteome Transmembrane Transmembrane helix | MARCCFYTAG | MARCCFYTAGTLSLLLLVTSVTLLVARVFQKAVDQTIEKNMVLQNGTKVFDSWEKPPLPVYIQFYFFNVTNPEEILQGEIPLLEEVGPYTYRELRNKANVQFGENGTTISAVTNKAYIFERNQSVGDPTVDLIRTINIPLLTVVEMAQQPFLREIIEAMLKAYQQTLFVTHTVHELLWGYKDEVLSLVHIFRPDVSPNFGLFYERNGTNDGEYVFLTGEDNYLNFTKIVEWNGKTSLDWWTTDTCNMINGTDGDSFHPLISKDETLYIFPSDFCRSVYITFSSFENVEGLPAFRYKVPAEILANSSENAGFCIPEGNCMD... | aminophospholipid transport endosome to plasma membrane protein transport positive regulation of neuron projection development protein targeting to lysosome receptor-mediated endocytosis regulation of carbohydrate catabolic process sensory perception of sound cytoplasm; endocytic vesicle membrane; lysosomal lumen; lyso... |
de novo' IMP biosynthetic process purine nucleotide biosynthetic process | cytoplasm; nucleus | ATP binding phosphoribosylaminoimidazolesuccinocarboxamide synthase activity | Saccharomyces cerevisiae | 3D-structure Acetylation ATP-binding Ligase Nucleotide-binding Purine biosynthesis Reference proteome | MSITKTELDG | MSITKTELDGILPLVARGKVRDIYEVDAGTLLFVATDRISAYDVIMENSIPEKGILLTKLSEFWFKFLSNDVRNHLVDIAPGKTIFDYLPAKLSEPKYKTQLEDRSLLVHKHKLIPLEVIVRGYITGSAWKEYVKTGTVHGLKQPQGLKESQEFPEPIFTPSTKAEQGEHDENISPAQAAELVGEDLSRRVAELAVKLYSKCKDYAKEKGIIIADTKFEFGIDEKTNEIILVDEVLTPDSSRFWNGASYKVGESQDSYDKQFLRDWLTANKLNGVNGVKMPQDIVDRTRAKYIEAYETLTGSKWSH | de novo' IMP biosynthetic process purine nucleotide biosynthetic process cytoplasm; nucleus ATP binding phosphoribosylaminoimidazolesuccinocarboxamide synthase activity Saccharomyces cerevisiae 3D-structure Acetylation ATP-binding Ligase Nucleotide-binding Purine biosynthesis Reference proteome MSITKTELDG MSITKTELDGIL... |
cell wall organization teichoic acid biosynthetic process | cytoplasm | glycerol-3-phosphate cytidylyltransferase activity metal ion binding | Bacillus subtilis | 3D-structure Cell wall biogenesis/degradation Cytoplasm Direct protein sequencing Nucleotidyltransferase Reference proteome Teichoic acid biosynthesis Transferase | MKKVITYGTF | MKKVITYGTFDLLHWGHIKLLERAKQLGDYLVVAISTDEFNLQKQKKAYHSYEHRKLILETIRYVDEVIPEKNWEQKKQDIIDHNIDVFVMGDDWEGKFDFLKDQCEVVYLPRTEGISTTKIKEEIAGL | cell wall organization teichoic acid biosynthetic process cytoplasm glycerol-3-phosphate cytidylyltransferase activity metal ion binding Bacillus subtilis 3D-structure Cell wall biogenesis/degradation Cytoplasm Direct protein sequencing Nucleotidyltransferase Reference proteome Teichoic acid biosynthesis Transferase MK... |
cytoplasmic translation embryonic brain development negative regulation of apoptotic process negative regulation of transcription by RNA polymerase II regulation of translation translation | cytosol; cytosolic large ribosomal subunit; cytosolic ribosome; endoplasmic reticulum; membrane; nucleus; protein-containing complex | RNA binding structural constituent of ribosome translation regulator activity | Homo sapiens | 3D-structure Autism Autism spectrum disorder Citrullination Cytoplasm Developmental protein Direct protein sequencing Disease variant Intellectual disability Isopeptide bond Reference proteome Ribonucleoprotein Ribosomal protein Translation regulation Ubl conjugation | MGRRPARCYR | MGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQLSSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQVIMSIRTKLQNKEHVIEALRRAKFKFPGRQKIHISKKWGFTKFNADEFEDMVAEKRLIPDGCGVKYIPSRGPLDKWRALHS | cytoplasmic translation embryonic brain development negative regulation of apoptotic process negative regulation of transcription by RNA polymerase II regulation of translation translation cytosol; cytosolic large ribosomal subunit; cytosolic ribosome; endoplasmic reticulum; membrane; nucleus; protein-containing comple... |
meiotic spindle disassembly mitotic cytokinesis negative regulation of protein localization to nucleolus phosphorylation positive regulation of ascospore-type prospore membrane formation regulation of exit from mitosis | cellular bud neck; cytoplasm; spindle pole; spindle pole body | ATP binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity | Saccharomyces cerevisiae | ATP-binding Cell cycle Cell division Cytoplasm Cytoskeleton Kinase Mitosis Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MNSMADTDRV | MNSMADTDRVNLTPIQRASEKSVQYHLKQVIGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIVNSSALTLAGTLNWMAPEILGNRGASTLSDIWSLGATVVEMLTKNPPYHNLTDANIYYAVENDTYYPPSSFSEPLKDFLSKCFVKNMYKRPTADQLLKHVWINSTENVKVDKLNKFKEDFTDADYHWDADFQEEKLNISPSKFSLAAAPA... | meiotic spindle disassembly mitotic cytokinesis negative regulation of protein localization to nucleolus phosphorylation positive regulation of ascospore-type prospore membrane formation regulation of exit from mitosis cellular bud neck; cytoplasm; spindle pole; spindle pole body ATP binding protein kinase activity pro... |
cellular bud site selection cytoskeleton organization establishment or maintenance of actin cytoskeleton polarity negative regulation of actin filament polymerization positive regulation of transcription by RNA polymerase II regulation of cell shape regulation of cytokinesis regulation of DNA-templated transcription re... | cell tip; cellular bud neck; cellular bud tip; cytoplasm; incipient cellular bud site; Kelch-containing formin regulatory complex; microtubule cytoskeleton; nucleus; protein phosphatase type 1 complex | protein phosphatase regulator activity | Saccharomyces cerevisiae | Acetylation Cell cycle Cell division Phosphoprotein Reference proteome SH3 domain | MSNKEEHVDE | MSNKEEHVDETSASGVKEVSSIAARHDNGYAPSLITSTSGMDSFQSHALLNDPTLIEDYSDIINNRPTSGSKLTLGNEDSESMGGSVVVTPTSNKSSPFNSKLNILSNAAEKGHDVLRNRDDDKELEEENVEKHMHSNSKRDQRHYKENSSELPDSYDYSDSEFEDNLERRLQEIETDSVDSADKDEVHFSVNNTMNPDVDDFSDGLKYAISEDEDEEENYSDDDDFDRKFQDSGFQGEKDDLEEENDDYQPLSPPRELDPDKLYALYAFNGHDSSHCQLGQDEPCILLNDQDAYWWLVKRITDGKIGFAPAEILETFPE... | cellular bud site selection cytoskeleton organization establishment or maintenance of actin cytoskeleton polarity negative regulation of actin filament polymerization positive regulation of transcription by RNA polymerase II regulation of cell shape regulation of cytokinesis regulation of DNA-templated transcription re... |
intracellular signal transduction pheromone response MAPK cascade pheromone-dependent signal transduction involved in conjugation with cellular fusion phosphorylation | cytoplasm; cytosol; mitotic spindle pole body; nucleus | ATP binding MAP kinase activity protein serine kinase activity protein serine/threonine kinase activity | Schizosaccharomyces pombe | ATP-binding Kinase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MASATSTPTI | MASATSTPTIADGNSNKESVATSRSPHTHDLNFELPEEYEMINLIGQGAYGVVCAALHKPSGLKVAVKKIHPFNHPVFCLRTLREIKLLRHFRHENIISILDILPPPSYQELEDVYIVQELMETDLYRVIRSQPLSDDHCQYFTYQILRALKAMHSAGVVHRDLKPSNLLLNANCDLKVADFGLARSTTAQGGNPGFMTEYVATRWYRAPEIMLSFREYSKAIDLWSTGCILAEMLSARPLFPGKDYHSQITLILNILGTPTMDDFSRIKSARARKYIKSLPFTPKVSFKALFPQASPDAIDLLEKLLTFNPDKRITAEE... | intracellular signal transduction pheromone response MAPK cascade pheromone-dependent signal transduction involved in conjugation with cellular fusion phosphorylation cytoplasm; cytosol; mitotic spindle pole body; nucleus ATP binding MAP kinase activity protein serine kinase activity protein serine/threonine kinase act... |
activation of innate immune response cellular hyperosmotic salinity response cellular response to fatty acid cellular response to gamma radiation cellular response to leukemia inhibitory factor cellular response to X-ray DNA damage response double-strand break repair double-strand break repair via nonhomologous end joi... | chromosome, telomeric region; cytoplasm; DNA-dependent protein kinase complex; DNA-dependent protein kinase-DNA ligase 4 complex; Ku70:Ku80 complex; nonhomologous end joining complex; nucleolus; nucleoplasm; nucleus; plasma membrane; protein-containing complex; protein-DNA complex; ribonucleoprotein complex; site of DN... | 5'-deoxyribose-5-phosphate lyase activity ATP binding ATP hydrolysis activity ATP-dependent activity, acting on DNA damaged DNA binding DNA end binding DNA helicase activity double-stranded telomeric DNA binding protein-containing complex binding RNA binding telomeric DNA binding transcription cis-regulatory region bin... | Mus musculus | Acetylation Activator ADP-ribosylation ATP-binding Chromosome DNA damage DNA recombination DNA repair DNA-binding Helicase Hydrolase Immunity Innate immunity Isopeptide bond Nucleotide-binding Nucleus Phosphoprotein Reference proteome Ribosome biogenesis Transcription Transcription regulation Ubl conjugation | MAWSGNKAAV | MAWSGNKAAVVLCVDVGVAMGNSFPGEESPIEQAKKVMTMFVQRQVFSESKDEIALVLYGTDGTDNALAGKDQYQNITVCRHLMLPDFDLLEDIGNKIQPSSQQADFLDALIVCMDLIQRETIGKKFGKKHIEVFTDLSSPFSQDQLDVIICNLKKSGISLQFFLPFPIDKNGEPGERGDLDSGLDHLKPSFPQKGLTEQQKEGIRMVTRVMLSLEGEDGLDEIYSFSESLRQLCVFKKIERRSMPWPCQLTIGPNLSIKIVAYKSIVQEKFKKSWVVVDARTLKKEDIQKETVYCLNDDDETEVSKEDTIQGYRYGSDI... | activation of innate immune response cellular hyperosmotic salinity response cellular response to fatty acid cellular response to gamma radiation cellular response to leukemia inhibitory factor cellular response to X-ray DNA damage response double-strand break repair double-strand break repair via nonhomologous end joi... |
antibody-dependent cellular cytotoxicity antigen processing and presentation of exogenous peptide antigen via MHC class I cell surface receptor signaling pathway mast cell activation nerve development neutrophil chemotaxis phagocytosis, engulfment phagocytosis, recognition positive regulation of phagocytosis positive r... | cell surface; external side of plasma membrane | IgG binding IgG receptor activity immunoglobulin receptor binding transmembrane signaling receptor activity | Rattus norvegicus | Alternative splicing Cell membrane Disulfide bond Glycoprotein IgG-binding protein Immunoglobulin domain Membrane Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix | MTLETQMFQN | MTLETQMFQNAHSGSQWLLPPLTMLLLFAFADRQTANLPKAVVKRDPPWIQVLKEDTVTLTCEGTHNPGNSSTQWFHNQSSTWGQVQASYTFKATVNDSGEYRCRMAHTSLSDPVHLEVISDWLLLQTPQLVFEEGETITLRCHSWKNKQLTKVLLFQNGKPVRYYYQSSNFSIPKANHSHSGNYYCKAYLGRTMHVSKPVTITVQGSATASTSSLVWFHAAFCLVMCLLFAVDTGLYFCVRRNLQTSGEDWRKSLSVGKYKAPQDK | antibody-dependent cellular cytotoxicity antigen processing and presentation of exogenous peptide antigen via MHC class I cell surface receptor signaling pathway mast cell activation nerve development neutrophil chemotaxis phagocytosis, engulfment phagocytosis, recognition positive regulation of phagocytosis positive r... |
10-formyltetrahydrofolate biosynthetic process heart development histidine biosynthetic process methionine biosynthetic process methionine metabolic process neural tube closure neutrophil homeostasis one-carbon metabolic process purine nucleotide biosynthetic process purine ribonucleotide biosynthetic process response ... | cytosol | ATP binding formate-tetrahydrofolate ligase activity methenyltetrahydrofolate cyclohydrolase activity methylenetetrahydrofolate dehydrogenase (NAD+) activity methylenetetrahydrofolate dehydrogenase (NADP+) activity methylenetetrahydrofolate dehydrogenase activity | Rattus norvegicus | Acetylation Amino-acid biosynthesis ATP-binding Cytoplasm Direct protein sequencing Histidine biosynthesis Hydrolase Ligase Methionine biosynthesis Multifunctional enzyme NADP Nucleotide-binding One-carbon metabolism Oxidoreductase Phosphoprotein Purine biosynthesis Reference proteome | MAPAGILNGK | MAPAGILNGKVVSAQIRNRLKTQVTQMQEQVPGFTPGLAILQVGDRDDSNLYINVKLKAAQEIGIKATHIKLPRTSTESEVLKYVISLNEDATVHGFIVQLPLDSENSINTEAVINAIAPEKDVDGLTSINAGKLARGDLKDCFIPCTPKGCLELIKETGVQIAGRHAVVVGRSKIVGAPMHDLLLWNNATVTTCHSKTADLDKEVNKGDILVVATGQPEMVKGEWIKPGAVVIDCGINYVPDDTKPNGRKVVGDVAYDEAKEKASFITPVPGGVGPMTVAMLMQSTVESAQRFLKKFKPGKWTIQYNKLNLKTPVPSDI... | 10-formyltetrahydrofolate biosynthetic process heart development histidine biosynthetic process methionine biosynthetic process methionine metabolic process neural tube closure neutrophil homeostasis one-carbon metabolic process purine nucleotide biosynthetic process purine ribonucleotide biosynthetic process response ... |
fungal-type cell wall organization | cell periphery; cytosol; extracellular region; fungal-type cell wall; side of membrane | lipase activity structural constituent of cell wall | Saccharomyces cerevisiae | Cell wall Direct protein sequencing Glycoprotein GPI-anchor Hydrolase Lipoprotein Membrane Reference proteome Secreted Signal Stress response | MSVSKIAFVL | MSVSKIAFVLSAIASLAVADTSAAETAELQAIIGDINSHLSDYLGLETGNSGFQIPSDVLSVYQQVMTYTDDAYTTLFSELDFDAITKTIVKLPWYTTRLSSEIAAALASVSPASSEAASSSEAASSSKAASSSEATSSAAPSSSAAPSSSAAPSSSAESSSKAVSSSVAPTTSSVSTSTVETASNAGQRVNAGAASFGAVVAGAAALLL | fungal-type cell wall organization cell periphery; cytosol; extracellular region; fungal-type cell wall; side of membrane lipase activity structural constituent of cell wall Saccharomyces cerevisiae Cell wall Direct protein sequencing Glycoprotein GPI-anchor Hydrolase Lipoprotein Membrane Reference proteome Secreted S... |
cholesterol homeostasis cholesterol metabolic process cholesterol transport chylomicron remnant clearance chylomicron remodeling fatty acid biosynthetic process fatty acid metabolic process glycerophospholipid catabolic process heparan sulfate proteoglycan biosynthetic process high-density lipoprotein particle remodeli... | cell surface; early endosome; extracellular space; high-density lipoprotein particle; late endosome; microvillus | 1-acyl-2-lysophosphatidylserine acylhydrolase activity acetylesterase activity acylglycerol lipase activity acyltransferase activity apolipoprotein binding chylomicron binding heparan sulfate proteoglycan binding heparin binding identical protein binding lipase activity lipid binding lipoprotein lipase activity low-den... | Mus musculus | Glycoprotein HDL Heparin-binding Hydrolase Lipid degradation Lipid metabolism Reference proteome Secreted Signal | MGNPLQISIF | MGNPLQISIFLVFCIFIQSSACGQGVGTEPFGRSLGATEASKPLKKPETRFLLFQDENDRLGCRLRPQHPETLQECGFNSSQPLIMIIHGWSVDGLLENWIWKIVSALKSRQSQPVNVGLVDWISLAYQHYTIAVQNTRIVGQDVAALLLWLEESAKFSRSKVHLIGYSLGAHVSGFAGSSMDGKNKIGRITGLDPAGPMFEGTSPNERLSPDDANFVDAIHTFTREHMGLSVGIKQPIAHYDFYPNGGSFQPGCHFLELYKHIAEHGLNAITQTIKCAHERSVHLFIDSLQHSDLQSIGFQCSDMGSFSQGLCLSCKKG... | cholesterol homeostasis cholesterol metabolic process cholesterol transport chylomicron remnant clearance chylomicron remodeling fatty acid biosynthetic process fatty acid metabolic process glycerophospholipid catabolic process heparan sulfate proteoglycan biosynthetic process high-density lipoprotein particle remodeli... |
intestinal cholesterol absorption lipid catabolic process lipid metabolic process post-embryonic development response to lipid response to peptide hormone | extracellular space | all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity lipase activity metal ion binding triglyceride lipase activity | Rattus norvegicus | Calcium Direct protein sequencing Disulfide bond Hydrolase Lipid degradation Lipid metabolism Metal-binding Reference proteome Secreted Signal | MLMLWTFAVL | MLMLWTFAVLLGAVAGKEVCFDKLGCFSDDAPWSGTIDRPLKALPWSPAQINTRFLLYTNENQDNYQKITSDASSIRNSNFKTNRKTRIIIHGFIDKGEENWLSDMCKNMFKVESVNCICVDWKGGSRATYTQATQNVRVVGAEVALLVNVLKSDLGHPPDNVHLIGHSLGSHVAGEAGKRTFGAIGRITGLDAAEPYFQGTPEEVRLDPTDAQFVDAIHTDAAPIIPNLGFGMSQTVGHLDFFPNGGMEMPGCQKNILSQIVDIDGIWEGTRDFAACNHLRSYKYYTDSIVNPTGFSGFSCSSYNVFSANKCFPCGSEG... | intestinal cholesterol absorption lipid catabolic process lipid metabolic process post-embryonic development response to lipid response to peptide hormone extracellular space all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity lipase activity metal ion binding triglyceride lipase activity Rattus n... |
angiogenesis camera-type eye morphogenesis cell adhesion endodermal cell differentiation endothelial cell proliferation extracellular matrix organization positive regulation of cell-substrate adhesion | collagen type VIII trimer; collagen-containing extracellular matrix; endoplasmic reticulum lumen; extracellular region; extracellular space | extracellular matrix structural constituent conferring tensile strength | Homo sapiens | Angiogenesis Basement membrane Cell adhesion Collagen Extracellular matrix Hydroxylation Reference proteome Repeat Secreted Signal | MAVLPGPLQL | MAVLPGPLQLLGVLLTISLSSIRLIQAGAYYGIKPLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQ... | angiogenesis camera-type eye morphogenesis cell adhesion endodermal cell differentiation endothelial cell proliferation extracellular matrix organization positive regulation of cell-substrate adhesion collagen type VIII trimer; collagen-containing extracellular matrix; endoplasmic reticulum lumen; extracellular region;... |
cellular response to interleukin-4 cytoplasmic translation translation | cytoplasm; cytosol; cytosolic large ribosomal subunit; cytosolic ribosome; nucleolus; protein-containing complex; ribosome; synapse | 5S rRNA binding RNA binding structural constituent of ribosome | Mus musculus | 3D-structure Acetylation Cytoplasm Isopeptide bond Methylation Nucleus Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation | MSHRKFSAPR | MSHRKFSAPRHGSLGFLPRKRSSRHRGKVKSFPKDDASKPVHLTAFLGYKAGMTHIVREVDRPGSKVNKKEVVEAVTIVETPPMVVVGIVGYVETPRGLRTFKTVFAEHISDECKRRFYKNWHKSKKKAFTKYCKKWQDDTGKKQLEKDFNSMKKYCQVIRIIAHTQMRLLPLRQKKAHLMEIQVNGGTVAEKLDWARERLEQQVPVNQVFGQDEMIDVIGVTKGKGYKGVTSRWHTKKLPRKTHRGLRKVACIGAWHPARVAFSVARAGQKGYHHRTEINKKIYKIGQGYLIKDGKLIKNNASTDYDLSDKSINPLGGF... | cellular response to interleukin-4 cytoplasmic translation translation cytoplasm; cytosol; cytosolic large ribosomal subunit; cytosolic ribosome; nucleolus; protein-containing complex; ribosome; synapse 5S rRNA binding RNA binding structural constituent of ribosome Mus musculus 3D-structure Acetylation Cytoplasm Isopep... |
cellular response to gamma radiation cellular senescence cerebral cortex development DNA damage response DNA repair double-strand break repair via homologous recombination meiotic cell cycle spermatogenesis | centrosome; chromatin; chromosome; chromosome, telomeric region; condensed nuclear chromosome; male germ cell nucleus; nuclear speck; nucleoplasm; nucleosome; nucleus; replication fork; site of DNA damage; site of double-strand break; XY body | damaged DNA binding DNA binding enzyme binding histone binding protein heterodimerization activity structural constituent of chromatin | Mus musculus | Acetylation Cell cycle Chromosome DNA damage DNA recombination DNA repair DNA-binding Isopeptide bond Meiosis Nucleosome core Nucleus Phosphoprotein Reference proteome Ubl conjugation | MSGRGKTGGK | MSGRGKTGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGHYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKSSATVGPKAPAVGKKASQASQEY | cellular response to gamma radiation cellular senescence cerebral cortex development DNA damage response DNA repair double-strand break repair via homologous recombination meiotic cell cycle spermatogenesis centrosome; chromatin; chromosome; chromosome, telomeric region; condensed nuclear chromosome; male germ cell nuc... |
photoreceptor cell maintenance retina development in camera-type eye signal transduction visual perception | photoreceptor outer segment membrane; plasma membrane | 3',5'-cyclic-GMP phosphodiesterase activity 3',5'-cyclic-nucleotide phosphodiesterase activity metal ion binding | Mus musculus | Acetylation Cell membrane Cell projection cGMP Hydrolase Lipoprotein Membrane Metal-binding Methylation Prenylation Reference proteome Repeat Sensory transduction Vision | MGEVTAEEVE | MGEVTAEEVEKFLDSNIGFAKQYYNFHYRGKVISDLLGAKEAAVDFSNYHDVNSVEESEIIFDLLRDVQENLQAEKCTFNVMKKLCFLLRADRMSLFMYRTRNGIAELATRLFNVHKDAVLEDCLVMPDSEIVFPLDMGVVGHVAHSKKIANVPNTEEDEHFCDFVDNLTEYQTKNILASPIMNGKDVVAIIMAVNKIDEPHFTKRDEEILLKYLNFVNLIMKVFHLSYLHNCETRRGQILLWSGSKVFEELTDIERQFHKALYTVRAFLNCDRYSVGLLDMTKQKEFFDVWPVLMGEAPAYSGPRTPDGREINFYKVID... | photoreceptor cell maintenance retina development in camera-type eye signal transduction visual perception photoreceptor outer segment membrane; plasma membrane 3',5'-cyclic-GMP phosphodiesterase activity 3',5'-cyclic-nucleotide phosphodiesterase activity metal ion binding Mus musculus Acetylation Cell membrane Cell pr... |
cellular response to glucose starvation central nervous system development dehydroascorbic acid transport glucose import glucose import across plasma membrane glucose transmembrane transport long-chain fatty acid import across plasma membrane photoreceptor cell maintenance protein-containing complex assembly response t... | apical plasma membrane; basolateral plasma membrane; cortical actin cytoskeleton; cytosol; female germ cell nucleus; female pronucleus; glucose transporter complex; Golgi membrane; membrane raft; midbody; photoreceptor inner segment; plasma membrane; presynapse; vesicle | D-glucose transmembrane transporter activity dehydroascorbic acid transmembrane transporter activity glucose transmembrane transporter activity identical protein binding long-chain fatty acid transporter activity protein self-association | Bos taurus | Acetylation Cell membrane Glycoprotein Membrane Phosphoprotein Reference proteome Sugar transport Transmembrane Transmembrane helix Transport | MEPTSKKLTG | MEPTSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVQRYGEPIPPATLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTELRGALGTLHQLGIVVGILIAQVFGLDSIMGNQELWPLLLSVIFIPALLQCILLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTRDLQEMKEESRQMMREKKVTILELFRSAAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQPVYATIGSGIVNTAF... | cellular response to glucose starvation central nervous system development dehydroascorbic acid transport glucose import glucose import across plasma membrane glucose transmembrane transport long-chain fatty acid import across plasma membrane photoreceptor cell maintenance protein-containing complex assembly response t... |
chloride transmembrane transport gamma-aminobutyric acid signaling pathway regulation of postsynaptic membrane potential response to xenobiotic stimulus synaptic transmission, GABAergic | chloride channel complex; dendrite membrane; GABA-A receptor complex; GABA-ergic synapse; microtubule cytoskeleton; neuron projection; nucleolus; plasma membrane; postsynapse; postsynaptic membrane; synapse; synaptic membrane | chloride channel activity GABA-A receptor activity GABA-gated chloride ion channel activity inhibitory extracellular ligand-gated monoatomic ion channel activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | Mus musculus | Cell membrane Chloride Chloride channel Disulfide bond Glycoprotein Ion channel Ion transport Lipoprotein Membrane Palmitate Postsynaptic cell membrane Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MAAKLLLLLC | MAAKLLLLLCLFSGLHARSRRVEEDENEDSPSNQKWVLAPKSQDTDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAECQLQLHNFPMDAHACPLTFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDFMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTTLGITTVLTMTTLSTIARKSLPRVSYVTAMDLFV... | chloride transmembrane transport gamma-aminobutyric acid signaling pathway regulation of postsynaptic membrane potential response to xenobiotic stimulus synaptic transmission, GABAergic chloride channel complex; dendrite membrane; GABA-A receptor complex; GABA-ergic synapse; microtubule cytoskeleton; neuron projection;... |
base-excision repair DNA damage response DNA recombination DNA repair DNA replication DNA-templated DNA replication double-strand break repair via homologous recombination meiotic cell cycle mismatch repair nucleotide-excision repair protein localization to chromosome protein localization to site of double-strand break... | chromosome, telomeric region; DNA replication factor A complex; nucleoplasm; nucleus; PML body; site of DNA damage; site of double-strand break | chromatin-protein adaptor activity damaged DNA binding G-rich strand telomeric DNA binding metal ion binding single-stranded DNA binding single-stranded telomeric DNA binding | Homo sapiens | 3D-structure Acetylation ADP-ribosylation Direct protein sequencing Disease variant DNA damage DNA recombination DNA repair DNA replication DNA-binding Isopeptide bond Metal-binding Nucleus Phosphoprotein Reference proteome Ubl conjugation Zinc Zinc-finger | MVGQLSEGAI | MVGQLSEGAIAAIMQKGDTNIKPILQVINIRPITTGNSPPRYRLLMSDGLNTLSSFMLATQLNPLVEEEQLSSNCVCQIHRFIVNTLKDGRRVVILMELEVLKSAEAVGVKIGNPVPYNEGLGQPQVAPPAPAASPAASSRPQPQNGSSGMGSTVSKAYGASKTFGKAAGPSLSHTSGGTQSKVVPIASLTPYQSKWTICARVTNKSQIRTWSNSRGEGKLFSLELVDESGEIRATAFNEQVDKFFPLIEVNKVYYFSKGTLKIANKQFTAVKNDYEMTFNNETSVMPCEDDHHLPTVQFDFTGIDDLENKSKDSLVDII... | base-excision repair DNA damage response DNA recombination DNA repair DNA replication DNA-templated DNA replication double-strand break repair via homologous recombination meiotic cell cycle mismatch repair nucleotide-excision repair protein localization to chromosome protein localization to site of double-strand break... |
base-excision repair base-excision repair, gap-filling cell redox homeostasis DNA catabolic process DNA demethylation DNA recombination DNA repair positive regulation of transcription by RNA polymerase II regulation of apoptotic process regulation of mRNA stability telomere maintenance telomere maintenance via base-exc... | centrosome; chromosome, telomeric region; cytoplasm; endoplasmic reticulum; mitochondrion; nuclear speck; nucleolus; nucleoplasm; nucleus; perinuclear region of cytoplasm; ribosome | 3'-5' exonuclease activity 3'-5'-DNA exonuclease activity chromatin DNA binding class II DNA-(apurinic or apyrimidinic site) endonuclease activity damaged DNA binding DNA binding DNA endonuclease activity DNA-(abasic site) binding DNA-(apurinic or apyrimidinic site) endonuclease activity double-stranded DNA 3'-5' DNA e... | Homo sapiens | 3D-structure Acetylation Activator Cleavage on pair of basic residues Cytoplasm Direct protein sequencing Disulfide bond DNA damage DNA recombination DNA repair DNA-binding Endonuclease Endoplasmic reticulum Exonuclease Hydrolase Magnesium Metal-binding Mitochondrion Nuclease Nucleus Phosphoprotein Reference proteome R... | MPKRGKKGAV | MPKRGKKGAVAEDGDELRTEPEAKKSKTAAKKNDKEAAGEGPALYEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQCPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL | base-excision repair base-excision repair, gap-filling cell redox homeostasis DNA catabolic process DNA demethylation DNA recombination DNA repair positive regulation of transcription by RNA polymerase II regulation of apoptotic process regulation of mRNA stability telomere maintenance telomere maintenance via base-exc... |
circadian regulation of gene expression circadian rhythm glycosphingolipid metabolic process negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of tran... | ATF4-CREB1 transcription factor complex; cytoplasm; nucleus; transcription regulator complex | DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specif... | Mus musculus | Activator Alternative promoter usage Alternative splicing Biological rhythms Cytoplasm DNA-binding Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation Ubl conjugation | MSKCGRKKYM | MSKCGRKKYMRTNVRQMTMETVESQQDRSVTRSVAEHSSAHMQTGQISVPTLAQVSVAGSGTGRGSPAVTLVQLPSGQTVQVQGVIQTPHPSVIQSPQIQTVQVATIAETDDSADSEVIDSHKRREILSRRPSYRKILNELSSDVPGIPKIEEEKSEEEGTPPNIATMAVPTSIYQTSTGQYIAIAQGGTIQISNPGSDGVQGLQALTMTNSGAPPPGATIVQYAAQSADGTQQFFVPGSQVVVQDEETDLAPSHMAAATGDMPTYQIRAPTTALPQGVVMAASPGSLHSPQQLAEEATRKRELRLMKNREAAKECRRRK... | circadian regulation of gene expression circadian rhythm glycosphingolipid metabolic process negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of tran... |
cell cycle intracellular signal transduction positive regulation of dendritic spine development protein phosphorylation | cytoplasm; cytosol; nucleus; protein-containing complex; septin cytoskeleton | ATP binding MAP kinase activity protein heterodimerization activity protein kinase activity protein kinase binding protein serine kinase activity protein serine/threonine kinase activity | Rattus norvegicus | ATP-binding Cell cycle Cytoplasm Kinase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase Ubl conjugation | MAEKFESLMN | MAEKFESLMNIHGFDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVKHALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQGPLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILESIPVVHEEDRQELLSVIPVYIRNDMTEPHKPLTQLLPGISREALDFLEQILTFSPMDRLTAEEALSHPYMSIYS... | cell cycle intracellular signal transduction positive regulation of dendritic spine development protein phosphorylation cytoplasm; cytosol; nucleus; protein-containing complex; septin cytoskeleton ATP binding MAP kinase activity protein heterodimerization activity protein kinase activity protein kinase binding protein ... |
carbohydrate metabolic process carbon catabolite repression of transcription from RNA polymerase II promoter by glucose negative regulation of transcription by RNA polymerase II negative regulation of transcription from RNA polymerase II promoter by glucose positive regulation of filamentous growth of a population of u... | cytoplasm; nuclear envelope lumen; nucleus | DNA-binding transcription repressor activity, RNA polymerase II-specific metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding | Saccharomyces cerevisiae | 3D-structure Carbohydrate metabolism DNA-binding Metal-binding Nucleus Phosphoprotein Reference proteome Repeat Repressor Transcription Transcription regulation Zinc Zinc-finger | MQSPYPMTQV | MQSPYPMTQVSNVDDGSLLKESKSKSKVAAKSEAPRPHACPICHRAFHRLEHQTRHMRIHTGEKPHACDFPGCVKRFSRSDELTRHRRIHTNSHPRGKRGRKKKVVGSPINSASSSATSIPDLNTANFSPPLPQQHLSPLIPIAIAPKENSSRSSTRKGRKTKFEIGESGGNDPYMVSSPKTMAKIPVSVKPPPSLALNNMNYQTSSASTALSSLSNSHSGSRLKLNALSSLQMMTPIASSAPRTVFIDGPEQKQLQQQQNSLSPRYSNTVILPRPRSLTDFQGLNNANPNNNGSLRAQTQSSVQLKRPSSVLSLNDLLV... | carbohydrate metabolic process carbon catabolite repression of transcription from RNA polymerase II promoter by glucose negative regulation of transcription by RNA polymerase II negative regulation of transcription from RNA polymerase II promoter by glucose positive regulation of filamentous growth of a population of u... |
dAMP salvage nucleoside phosphate biosynthetic process phosphorylation pyrimidine nucleotide metabolic process | cytoplasm; cytosol; mitochondrion; nucleoplasm | ATP binding cytidine kinase activity deoxyadenosine kinase activity deoxycytidine kinase activity deoxyguanosine kinase activity protein homodimerization activity | Homo sapiens | 3D-structure ATP-binding Direct protein sequencing Kinase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Transferase | MATPPKRSCP | MATPPKRSCPSFSASSEGTRIKKISIEGNIAAGKSTFVNILKQLCEDWEVVPEPVARWCNVQSTQDEFEELTMSQKNGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESECMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL | dAMP salvage nucleoside phosphate biosynthetic process phosphorylation pyrimidine nucleotide metabolic process cytoplasm; cytosol; mitochondrion; nucleoplasm ATP binding cytidine kinase activity deoxyadenosine kinase activity deoxycytidine kinase activity deoxyguanosine kinase activity protein homodimerization activity... |
intercellular transport monoatomic ion transmembrane transport phototransduction phototransduction, visible light visual behavior | basolateral plasma membrane; gap junction; membrane; plasma membrane | gap junction channel activity | Drosophila melanogaster | Cell junction Cell membrane Gap junction Ion channel Ion transport Membrane Reference proteome Transmembrane Transmembrane helix Transport | MYKLLGSLKS | MYKLLGSLKSYLKWQDIQTDNAVFRLHNSFTTVLLLTCSLIITATQYVGQPISCIVNGVPPHVVNTFCWIHSTFTMPDAFRRQVGREVAHPGVANDFGDEDAKKYYTYYQWVCFVLFFQAMACYTPKFLWNKFEGGLMRMIVMGLNITICTREEKEAKRDALLDYLIKHVKRHKLYAIRYWACEFLCCINIIVQMYLMNRFFDGEFLSYGTNIMKLSDVPQEQRVDPMVYVFPRVTKCTFHKYGPSGSLQKHDSLCILPLNIVNEKTYVFIWFWFWILLVLLIGLIVFRGCIIFMPKFRPRLLNASNRMIPMEICRSLSR... | intercellular transport monoatomic ion transmembrane transport phototransduction phototransduction, visible light visual behavior basolateral plasma membrane; gap junction; membrane; plasma membrane gap junction channel activity Drosophila melanogaster Cell junction Cell membrane Gap junction Ion channel Ion transport ... |
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