Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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antibacterial humoral response biofilm matrix disassembly cellular response to lipopolysaccharide defense response to fungus defense response to Gram-negative bacterium defense response to Gram-positive bacterium monocyte chemotaxis negative regulation of T cell activation neutrophil activation neutrophil-mediated kill... | cytoplasm; cytoplasmic stress granule; cytosol; extracellular space; intracellular membrane-bounded organelle; lysosome; membrane; nucleus; plasma membrane; secretory granule | caspase binding heparin binding peptidase activity receptor ligand activity serine-type endopeptidase activity serine-type peptidase activity | Mus musculus | Antibiotic Antimicrobial Cell membrane Chemotaxis Cytoplasm Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Lysosome Membrane Nucleus Protease Reference proteome Secreted Serine protease Signal Zymogen | MQPLLLLLTF | MQPLLLLLTFILLQGDEAGKIIGGREARPHSYPYMAFLLIQSPEGLSACGGFLVREDFVLTAAHCLGSSINVTLGAHNIQMRERTQQLITVLRAIRHPDYNPQNIRNDIMLLQLRRRARRSGSVKPVALPQASKKLQPGDLCTVAGWGRVSQSRGTNVLQEVQLRVQMDQMCANRFQFYNSQTQICVGNPRERKSAFRGDSGGPLVCSNVAQGIVSYGSNNGNPPAVFTKIQSFMPWIKRTMRRFAPRYQRPANSLSQAQT | antibacterial humoral response biofilm matrix disassembly cellular response to lipopolysaccharide defense response to fungus defense response to Gram-negative bacterium defense response to Gram-positive bacterium monocyte chemotaxis negative regulation of T cell activation neutrophil activation neutrophil-mediated kill... |
elastin catabolic process evasion of host immune response via modulation of host complement system protein catabolic process proteolysis | extracellular region; extracellular space | fibrinogen binding IgE binding peptidase activity serine-type endopeptidase activity serine-type peptidase activity | Aspergillus fumigatus | Allergen Direct protein sequencing Glycoprotein Hydrolase Protease Reference proteome Secreted Serine protease Signal Virulence Zymogen | MLSIKRTLLL | MLSIKRTLLLLGAVLPAVFGAPVQETRRAAQKIPGKYIVTFKPGTDTATIESHTLWATDLHKRNLERRDTTSGEPPVGIEKSYKIKDFAAYAGSFDDATIEEIRKSADVAHVEEDQIWYLDALTTQKGAPWGLGSISHKGQASTDYIYDTSAGAGTYAYVVDSGINVNHVEFESRASLAYNAAGGSHVDSIGHGTHVAGTIGGKTYGVAKKTNLLSVKVFQGESSSTSIILDGFNWAVNDIVSKGRTKKAAINMSLGGGYSYAFNNAVENAFDEGVLSVVAAGNENSDASNTSPASAPNALTVAAINKSNARASFSNYGS... | elastin catabolic process evasion of host immune response via modulation of host complement system protein catabolic process proteolysis extracellular region; extracellular space fibrinogen binding IgE binding peptidase activity serine-type endopeptidase activity serine-type peptidase activity Aspergillus fumigatus Al... |
acetate catabolic process carbon utilization fatty acid catabolic process glyoxylate cycle tricarboxylic acid cycle | glyoxysome; peroxisomal matrix; peroxisome | isocitrate lyase activity metal ion binding methylisocitrate lyase activity | Emericella nidulans | 3D-structure Glyoxylate bypass Glyoxysome Lyase Magnesium Metal-binding Peroxisome Reference proteome Tricarboxylic acid cycle | MSYIEEEDQR | MSYIEEEDQRYWDEVAAVKNWWKDSRWRYTKRPFTAEQIVAKRGNLKIEYPSNVQAKKLWGILERNFKNKEASFTYGCLDPTMVTQMAKYLDTVYVSGWQSSSTASSTDEPSPDLADYPMNTVPNKVNHLWMAQLFHDRKQREERMTTPKDQRHKVANVDYLRPIIADADTGHGGLTAVMKLTKLFVERGAAGIHIEDQAPGTKKCGHMAGKVLVPISEHINRLVAIRAQADIMGTDLLAIARTDSEAATLITSTIDHRDHPFIIGSTNPDIQPLNDLMVMAEQAGKNGAELQAIEDEWLAKAGLKLFNDAVVDAINNSP... | acetate catabolic process carbon utilization fatty acid catabolic process glyoxylate cycle tricarboxylic acid cycle glyoxysome; peroxisomal matrix; peroxisome isocitrate lyase activity metal ion binding methylisocitrate lyase activity Emericella nidulans 3D-structure Glyoxylate bypass Glyoxysome Lyase Magnesium Metal-... |
ascending aorta development blood vessel morphogenesis bone mineralization cell chemotaxis cellular response to chemokine collagen fibril organization connective tissue development descending aorta development DNA biosynthetic process elastic fiber assembly heart development lung development muscle cell cellular homeos... | collagen trimer; collagen-containing extracellular matrix; extracellular region; extracellular space | collagen binding copper ion binding molecular adaptor activity protein-lysine 6-oxidase activity small molecule binding | Homo sapiens | Aortic aneurysm Copper Disease variant Disulfide bond Glycoprotein LTQ Metal-binding Oxidoreductase Reference proteome Secreted Signal Sulfation TPQ | MRFAWTVLLL | MRFAWTVLLLGPLQLCALVHCAPPAAGQQQPPREPPAAPGAWRQQIQWENNGQVFSLLSLGSQYQPQRRRDPGAAVPGAANASAQQPRTPILLIRDNRTAAARTRTAGSSGVTAGRPRPTARHWFQAGYSTSRAREAGASRAENQTAPGEVPALSNLRPPSRVDGMVGDDPYNPYKYSDDNPYYNYYDTYERPRPGGRYRPGYGTGYFQYGLPDLVADPYYIQASTYVQKMSMYNLRCAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDANTQRRVAEGHK... | ascending aorta development blood vessel morphogenesis bone mineralization cell chemotaxis cellular response to chemokine collagen fibril organization connective tissue development descending aorta development DNA biosynthetic process elastic fiber assembly heart development lung development muscle cell cellular homeos... |
folic acid biosynthetic process para-aminobenzoic acid biosynthetic process tetrahydrofolate biosynthetic process | cytosol | 4-amino-4-deoxychorismate lyase activity pyridoxal phosphate binding | Escherichia coli | 3D-structure Direct protein sequencing Folate biosynthesis Lyase Pyridoxal phosphate Reference proteome | MFLINGHKQE | MFLINGHKQESLAVSDRATQFGDGCFTTARVIDGKVSLLSAHIQRLQDACQRLMISCDFWPQLEQEMKTLAAEQQNGVLKVVISRGSGGRGYSTLNSGPATRILSVTAYPAHYDRLRNEGITLALSPVRLGRNPHLAGIKHLNRLEQVLIRSHLEQTNADEALVLDSEGWVTECCAANLFWRKGNVVYTPRLDQAGVNGIMRQFCIRLLAQSSYQLVEVQASLEESLQADEMVICNALMPVMPVCACGDVSFSSATLYEYLAPLCERPN | folic acid biosynthetic process para-aminobenzoic acid biosynthetic process tetrahydrofolate biosynthetic process cytosol 4-amino-4-deoxychorismate lyase activity pyridoxal phosphate binding Escherichia coli 3D-structure Direct protein sequencing Folate biosynthesis Lyase Pyridoxal phosphate Reference proteome MFLINGHK... |
cell wall organization peptidoglycan biosynthetic process peptidoglycan metabolic process | outer membrane-bounded periplasmic space; plasma membrane | lytic endotransglycosylase activity | Escherichia coli | 3D-structure Cell inner membrane Cell membrane Cell wall biogenesis/degradation Lyase Membrane Reference proteome Transmembrane Transmembrane helix | MKKVLLIILL | MKKVLLIILLLLVVLGIAAGVGVWKVRHLADSKLLIKEETIFTLKPGTGRLALGEQLYADKIINRPRVFQWLLRIEPDLSHFKAGTYRFTPQMTVREMLKLLESGKEAQFPLRLVEGMRLSDYLKQLREAPYIKHTLSDDKYATVAQALELENPEWIEGWFWPDTWMYTANTTDVALLKRAHKKMVKAVDSAWEGRADGLPYKDKNQLVTMASIIEKETAVASERDKVASVFINRLRIGMRLQTDPTVIYGMGERYNGKLSRADLETPTAYNTYTITGLPPGAIATPGADSLKAAAHPAKTPYLYFVADGKGGHTFNTNL... | cell wall organization peptidoglycan biosynthetic process peptidoglycan metabolic process outer membrane-bounded periplasmic space; plasma membrane lytic endotransglycosylase activity Escherichia coli 3D-structure Cell inner membrane Cell membrane Cell wall biogenesis/degradation Lyase Membrane Reference proteome Trans... |
antibacterial humoral response antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to lipopolysaccharide defense response to bacterium defense response to Gram-negative bacterium defense response to Gram-positive bacterium disruption of plasma membrane integrity in another organism... | extracellular space; intracellular membrane-bounded organelle; midbody; secretory granule | pore-forming activity protein homodimerization activity | Mus musculus | Antibiotic Antimicrobial Defensin Direct protein sequencing Disulfide bond Reference proteome Secreted Signal | MKPLVLLSAL | MKPLVLLSALVLLSFQVQADPIQNTDEETKTEEQSGEEDQAVSVSFGDREGASLQEESLRDLVCYCRTRGCKRRERMNGTCRKGHLMYTLCCR | antibacterial humoral response antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to lipopolysaccharide defense response to bacterium defense response to Gram-negative bacterium defense response to Gram-positive bacterium disruption of plasma membrane integrity in another organism... |
antibacterial humoral response antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to lipopolysaccharide defense response to bacterium defense response to Gram-negative bacterium defense response to Gram-positive bacterium disruption of plasma membrane integrity in another organism... | extracellular space; intracellular membrane-bounded organelle; midbody; secretory granule | pore-forming activity protein homodimerization activity | Mus musculus | Antibiotic Antimicrobial Defensin Direct protein sequencing Disulfide bond Reference proteome Secreted Signal | MKTLVLLSAL | MKTLVLLSALVLLAFQVQADPIQNTDEETKTEEQPGEDDQAVSVSFGDPEGSSLQEESLRDLVCYCRKRGCKRRERMNGTCRKGHLMYTLCCR | antibacterial humoral response antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to lipopolysaccharide defense response to bacterium defense response to Gram-negative bacterium defense response to Gram-positive bacterium disruption of plasma membrane integrity in another organism... |
antibacterial humoral response antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to lipopolysaccharide defense response to bacterium defense response to Gram-negative bacterium defense response to Gram-positive bacterium disruption of plasma membrane integrity in another organism... | azurophil granule; extracellular space; transport vesicle | phospholipid binding pore-forming activity protein homodimerization activity | Mus musculus | 3D-structure Antibiotic Antimicrobial Cytoplasmic vesicle Defensin Direct protein sequencing Disulfide bond Reference proteome Secreted Signal | MKTLVLLSAL | MKTLVLLSALVLLAFQVQADPIQNTDEETKTEEQPGEEDQAVSISFGGQEGSALHEKSLRGLLCYCRKGHCKRGERVRGTCGIRFLYCCPRR | antibacterial humoral response antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to lipopolysaccharide defense response to bacterium defense response to Gram-negative bacterium defense response to Gram-positive bacterium disruption of plasma membrane integrity in another organism... |
cellular response to oxidative stress hydrogen peroxide catabolic process | extracellular region | heme binding lactoperoxidase activity metal ion binding | Arthromyces ramosus | 3D-structure Calcium Direct protein sequencing Disulfide bond Glycoprotein Heme Hydrogen peroxide Iron Metal-binding Oxidoreductase Peroxidase Pyrrolidone carboxylic acid Secreted Signal | MKLSLFSTFA | MKLSLFSTFAAVIIGALALPQGPGGGGGSVTCPGGQSTSNSQCCVWFDVLDDLQTNFYQGSKCESPVRKILRIVFHDAIGFSPALTAAGQFGGGGADGSIIAHSNIELAFPANGGLTDTIEALRAVGINHGVSFGDLIQFATAVGMSNCPGSPRLEFLTGRSNSSQPSPPSLIPGPGNTVTAILDRMGDAGFSPDEVVDLLAAHSLASQEGLNSAIFRSPLDSTPQVFDTQFYIETLLKGTTQPGPSLGFAEELSPFPGEFRMRSDALLARDSRTACRWQSMTSSNEVMGQRYRAAMAKMSVLGFDRNALTDCSDVIPSA... | cellular response to oxidative stress hydrogen peroxide catabolic process extracellular region heme binding lactoperoxidase activity metal ion binding Arthromyces ramosus3D-structure Calcium Direct protein sequencing Disulfide bond Glycoprotein Heme Hydrogen peroxide Iron Metal-binding Oxidoreductase Peroxidase Pyrroli... |
cellular response to oxidative stress hydrogen peroxide catabolic process | extracellular region | heme binding lactoperoxidase activity metal ion binding | Coprinopsis cinerea | 3D-structure Calcium Direct protein sequencing Disulfide bond Glycoprotein Heme Hydrogen peroxide Iron Metal-binding Oxidoreductase Peroxidase Pyrrolidone carboxylic acid Secreted Signal | MKLSLLSTFA | MKLSLLSTFAAVIIGALALPQGPGGGGSVTCPGGQSTSNSQCCVWFDVLDDLQTNFYQGSKCESPVRKILRIVFHDAIGFSPALTAAGQFGGGGADGSIIAHSNIELAFPANGGLTDTVEALRAVGINHGVSFGDLIQFATAVGMSNCPGSPRLEFLTGRSNSSQPSPPSLIPGPGNTVTAILDRMGDAGFSPDEVVDLLAAHSLASQEGLNSAIFRSPLDSTPQVFDTQFYIETLLKGTTQPGPSLGFAEELSPFPGEFRMRSDALLARDSRTACRWQSMTSSNEVMGQRYRAAMAKMSVLGFDRNALTDCSDVIPSAV... | cellular response to oxidative stress hydrogen peroxide catabolic process extracellular region heme binding lactoperoxidase activity metal ion binding Coprinopsis cinerea 3D-structure Calcium Direct protein sequencing Disulfide bond Glycoprotein Heme Hydrogen peroxide Iron Metal-binding Oxidoreductase Peroxidase Pyrro... |
ascospore-type prospore membrane formation fungal-type cell wall organization | cellular birth scar; extracellular region; fungal-type cell wall; fungal-type vacuole; prospore membrane; side of membrane | structural constituent of cell wall | Saccharomyces cerevisiae | Cell wall Direct protein sequencing Glycoprotein GPI-anchor Lipoprotein Membrane Reference proteome Secreted Signal | MKFSTALSVA | MKFSTALSVALFALAKMVIADSEEFGLVSIRSGSDLQYLSVYSDNGTLKLGSGSGSFEATITDDGKLKFDDDKYAVVNEDGSFKEGSESDAATGFSIKDGHLNYKSSSGFYAIKDGSSYIFSSKQSDDATGVAIRPTSKSGSVAADFSPSDSSSSSSASASSASASSSTKHSSSIESVETSTTVETSSASSPTASVISQITDGQIQAPNTVYEQTENAGAKAAVGMGAGALAVAAAYLL | ascospore-type prospore membrane formation fungal-type cell wall organization cellular birth scar; extracellular region; fungal-type cell wall; fungal-type vacuole; prospore membrane; side of membrane structural constituent of cell wall Saccharomyces cerevisiae Cell wall Direct protein sequencing Glycoprotein GPI-anch... |
generation of catalytic spliceosome for first transesterification step generation of catalytic spliceosome for second transesterification step RNA splicing | nucleus; U2-type catalytic step 1 spliceosome; U2-type catalytic step 2 spliceosome | metal ion binding U2 snRNA binding | Saccharomyces cerevisiae | 3D-structure Metal-binding mRNA processing mRNA splicing Nucleus Reference proteome Spliceosome Zinc | MSERKAINKY | MSERKAINKYYPPDYNPLEAEKLSRKMAKKLKTMNKSHASIRLMTPFSMRCLECNEYIPKSRKFNGKKELLKEKYLDSIKIYRLTISCPRCANSIAFRTDPGNSDYVMEVGGVRNYVPQKPNDDLNAKTAVESIDETLQRLVREKEMEQNEKMGIKEQADDKMDLLEKRLAKIQQEQEDDEELENLRKKNLEMSQRAEMINRSKHAQQEKAVTTDDLDNLVDQVFDNHRQRTNKPGNNNDEKRTPLFNPTSTKGKIQKKSSVRTNPLGIVIKRGKSLK | generation of catalytic spliceosome for first transesterification step generation of catalytic spliceosome for second transesterification step RNA splicing nucleus; U2-type catalytic step 1 spliceosome; U2-type catalytic step 2 spliceosome metal ion binding U2 snRNA binding Saccharomyces cerevisiae 3D-structure Metal-... |
triglyceride catabolic process triglyceride metabolic process | cell periphery; cytoplasm; endoplasmic reticulum; lipid droplet; membrane; mitochondrial outer membrane; mitochondrion; plasma membrane | acylglycerol lipase activity lipase activity serine hydrolase activity | Saccharomyces cerevisiae | 3D-structure Cytoplasm Endoplasmic reticulum Hydrolase Lipid droplet Membrane Mitochondrion Mitochondrion outer membrane Reference proteome | MAPYPYKVQT | MAPYPYKVQTTVPELQYENFDGAKFGYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLEHFVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIGSGPLIILHPHTMYNKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYRAFLGSDPMSVPLYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFIQDCPSADKELKLYPGARHSIFSLETDKVFNTVFNDMKQWLDKHTTTEAKP | triglyceride catabolic process triglyceride metabolic process cell periphery; cytoplasm; endoplasmic reticulum; lipid droplet; membrane; mitochondrial outer membrane; mitochondrion; plasma membrane acylglycerol lipase activity lipase activity serine hydrolase activity Saccharomyces cerevisiae 3D-structure Cytoplasm En... |
branching involved in mammary gland duct morphogenesis motor neuron axon guidance negative regulation of mammary gland epithelial cell proliferation positive regulation of DNA-templated transcription positive regulation of gene expression positive regulation of keratinocyte differentiation positive regulation of transc... | chromosome; nucleolus; nucleus | DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Mus musculus | Activator Alternative splicing DNA-binding Isopeptide bond Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Ubl conjugation | MERRMKGGYL | MERRMKGGYLDQRVPYTFCSKSPGNGSLGEALMVPQGKLMDPGSLPPSDSEDLFQDLSHFQETWLAEAQVPDSDEQFVPDFHSENSFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHHGEQCLYSSAYDSPRQIAIKSPAPGAPGQSPLQPFSRAEQQQSLLRASSSSQSHPGHGYLGEHSSVFQQPVDMCHSFTSPQGGGREPLPAPYQHQLSEPCPPYPQQNFKQEYHDPLYEQAGQPASSQGGVSGHRYPGAGVVIKQERTDFAYDSDVPGCASMYLHPEGFSGPSPGDGVMGYGYEKSLRPFPDDVCIVPEKFEG... | branching involved in mammary gland duct morphogenesis motor neuron axon guidance negative regulation of mammary gland epithelial cell proliferation positive regulation of DNA-templated transcription positive regulation of gene expression positive regulation of keratinocyte differentiation positive regulation of transc... |
negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II | chromatin; cytosol; nucleoplasm; nucleus | chromatin binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded D... | Homo sapiens | 3D-structure Activator Alternative splicing DNA-binding Isopeptide bond Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation Ubl conjugation | MDSAITLWQF | MDSAITLWQFLLQLLQKPQNKHMICWTSNDGQFKLLQAEEVARLWGIRKNKPNMNYDKLSRALRYYYVKNIIKKVNGQKFVYKFVSYPEILNMDPMTVGRIEGDCESLNFSEVSSSSKDVENGGKDKPPQPGAKTSSRNDYIHSGLYSSFTLNSLNSSNVKLFKLIKTENPAEKLAEKKSPQEPTPSVIKFVTTPSKKPPVEPVAATISIGPSISPSSEETIQALETLVSPKLPSLEAPTSASNVMTAFATTPPISSIPPLQEPPRTPSPPLSSHPDIDTDIDSVASQPMELPENLSLEPKDQDSVLLEKDKVNNSSRSK... | negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II chromatin; cytosol; nucleoplasm; nucleus chromatin binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding... |
protein autophosphorylation regulation of rhodopsin mediated signaling pathway regulation of signal transduction signal transduction visual perception | cytoplasm; photoreceptor disc membrane | ATP binding rhodopsin kinase activity | Bos taurus | 3D-structure ATP-binding Cell projection Direct protein sequencing Kinase Lipoprotein Membrane Methylation Nucleotide-binding Phosphoprotein Prenylation Reference proteome Sensory transduction Serine/threonine-protein kinase Transferase Vision | MDFGSLETVV | MDFGSLETVVANSAFIAARGSFDASSGPASRDRKYLARLKLPPLSKCEALRESLDLGFEGMCLEQPIGKRLFQQFLRTHEQHGPALQLWKDIEDYDTADDALRPQKAQALRAAYLEPQAQLFCSFLDAETVARARAGAGDGLFQPLLRAVLAHLGQAPFQEFLDSLYFLRFLQWKWLEAQPMGEDWFLDFRVLGRGGFGEVFACQMKATGKLYACKKLNKKRLKKRKGYQGAMVEKKILAKVHSRFIVSLAYAFETKTDLCLVMTIMNGGDIRYHIYNVDEDNPGFQEPRAIFYTAQIVSGLEHLHQRNIIYRDLKPENV... | protein autophosphorylation regulation of rhodopsin mediated signaling pathway regulation of signal transduction signal transduction visual perception cytoplasm; photoreceptor disc membrane ATP binding rhodopsin kinase activity Bos taurus 3D-structure ATP-binding Cell projection Direct protein sequencing Kinase Lipopro... |
cellular response to reactive oxygen species fatty acid beta-oxidation negative regulation of epithelial cell proliferation negative regulation of fibroblast proliferation peroxisome organization pexophagy protein destabilization protein import into peroxisome matrix protein import into peroxisome matrix, receptor recy... | Cdc73/Paf1 complex; cytosol; membrane; peroxisomal membrane | protein transmembrane transporter activity ubiquitin protein ligase activity zinc ion binding | Homo sapiens | Acetylation Disease variant Disulfide bond Membrane Metal-binding Peroxisome Peroxisome biogenesis Peroxisome biogenesis disorder Protein transport Reference proteome Transferase Transmembrane Transmembrane helix Transport Ubl conjugation pathway Zellweger syndrome Zinc Zinc-finger | MASRKENAKS | MASRKENAKSANRVLRISQLDALELNKALEQLVWSQFTQCFHGFKPGLLARFEPEVKACLWVFLWRFTIYSKNATVGQSVLNIKYKNDFSPNLRYQPPSKNQKIWYAVCTIGGRWLEERCYDLFRNHHLASFGKVKQCVNFVIGLLKLGGLINFLIFLQRGKFATLTERLLGIHSVFCKPQNICEVGFEYMNRELLWHGFAEFLIFLLPLINVQKLKAKLSSWCIPLTGAPNSDNTLATSGKECALCGEWPTMPHTIGCEHIFCYFCAKSSFLFDVYFTCPKCGTEVHSLQPLKSGIEMSEVNAL | cellular response to reactive oxygen species fatty acid beta-oxidation negative regulation of epithelial cell proliferation negative regulation of fibroblast proliferation peroxisome organization pexophagy protein destabilization protein import into peroxisome matrix protein import into peroxisome matrix, receptor recy... |
acetylcholine biosynthetic process neuromuscular synaptic transmission neurotransmitter transport phosphatidylcholine biosynthetic process | cytoplasm; cytosol; neuron projection; nucleus; synapse | choline O-acetyltransferase activity | Homo sapiens | 3D-structure Acyltransferase Alternative splicing Congenital myasthenic syndrome Direct protein sequencing Disease variant Neurotransmitter biosynthesis Phosphoprotein Reference proteome Transferase | MGLRTAKKRG | MGLRTAKKRGLGGGGKWKREEGGGTRGRREVRPACFLQSGGRGDPGDVGGPAGNPGCSPHPRAATRPPPLPAHTPAHTPEWCGAASAEAAEPRRAGPHLCIPAPGLTKTPILEKVPRKMAAKTPSSEESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKLLERQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQLRFAASLISGVLSYKALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVAQNSSIMPEPEHVIVACCNQFFVLDVVIN... | acetylcholine biosynthetic process neuromuscular synaptic transmission neurotransmitter transport phosphatidylcholine biosynthetic process cytoplasm; cytosol; neuron projection; nucleus; synapse choline O-acetyltransferase activity Homo sapiens 3D-structure Acyltransferase Alternative splicing Congenital myasthenic syn... |
carnitine catabolic process carnitine metabolic process, CoA-linked cellular lipid catabolic process fatty acid beta-oxidation using acyl-CoA dehydrogenase long-chain fatty acid catabolic process negative regulation of fatty acid biosynthetic process negative regulation of fatty acid oxidation positive regulation of co... | cytoplasm; mitochondrial matrix; mitochondrial membrane; mitochondrion | fatty-acyl-CoA binding flavin adenine dinucleotide binding identical protein binding long-chain-acyl-CoA dehydrogenase activity palmitoyl-CoA oxidase activity | Homo sapiens | Acetylation FAD Fatty acid metabolism Flavoprotein Lipid metabolism Mitochondrion Oxidoreductase Phosphoprotein Reference proteome Transit peptide | MAARLLRGSL | MAARLLRGSLRVLGGHRAPRQLPAARCSHSGGEERLETPSAKKLTDIGIRRIFSPEHDIFRKSVRKFFQEEVIPHHSEWEKAGEVSREVWEKAGKQGLLGVNIAEHLGGIGGDLYSAAIVWEEQAYSNCSGPGFSIHSGIVMSYITNHGSEEQIKHFIPQMTAGKCIGAIAMTEPGAGSDLQGIKTNAKKDGSDWILNGSKVFISNGSLSDVVIVVAVTNHEAPSPAHGISLFLVENGMKGFIKGRKLHKMGLKAQDTAELFFEDIRLPASALLGEENKGFYYIMKELPQERLLIADVAISASEFMFEETRNYVKQRKAF... | carnitine catabolic process carnitine metabolic process, CoA-linked cellular lipid catabolic process fatty acid beta-oxidation using acyl-CoA dehydrogenase long-chain fatty acid catabolic process negative regulation of fatty acid biosynthetic process negative regulation of fatty acid oxidation positive regulation of co... |
ethanol oxidation response to ethanol retinoic acid metabolic process retinol metabolic process | cytosol; extracellular exosome | alcohol dehydrogenase (NAD+) activity alcohol dehydrogenase activity, zinc-dependent NAD-retinol dehydrogenase activity zinc ion binding | Homo sapiens | Alternative splicing Cytoplasm Metal-binding NAD Oxidoreductase Phosphoprotein Reference proteome Zinc | MSTTGQVIRC | MSTTGQVIRCKAAILWKPGAPFSIEEVEVAPPKAKEVRIKVVATGLCGTEMKVLGSKHLDLLYPTILGHEGAGIVESIGEGVSTVKPGDKVITLFLPQCGECTSCLNSEGNFCIQFKQSKTQLMSDGTSRFTCKGKSIYHFGNTSTFCEYTVIKEISVAKIDAVAPLEKVCLISCGFSTGFGAAINTAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIGVDVNKEKFKKAQELGATECLNPQDLKKPIQEVLFDMTDAGIDFCFEAIGNLDVLAAALASCNESYGVCVVVGVLPASVQLKISGQLFFSGRSLKGSVF... | ethanol oxidation response to ethanol retinoic acid metabolic process retinol metabolic process cytosol; extracellular exosome alcohol dehydrogenase (NAD+) activity alcohol dehydrogenase activity, zinc-dependent NAD-retinol dehydrogenase activity zinc ion binding Homo sapiens Alternative splicing Cytoplasm Metal-bindin... |
behavioral fear response cGMP-mediated signaling chemical synaptic transmission feeding behavior G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger G protein-coupled serotonin receptor signaling pathway intracellular calcium ion homeostasis locomotory behavior phospholipase C-ac... | dendrite; G protein-coupled serotonin receptor complex; plasma membrane; synapse | 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding G protein-coupled serotonin receptor activity Gq/11-coupled serotonin receptor activity identical protein binding neurotransmitter receptor activity serotonin binding | Homo sapiens | 3D-structure Alternative splicing Behavior Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome RNA editing Signal Transducer Transmembrane Transmembrane helix | MVNLRNAVHS | MVNLRNAVHSFLVHLIGLLVWQSDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSIVIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYVLRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQNARRRKKKERRPRGTMQAINNERKASKVLGIVFFVF... | behavioral fear response cGMP-mediated signaling chemical synaptic transmission feeding behavior G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger G protein-coupled serotonin receptor signaling pathway intracellular calcium ion homeostasis locomotory behavior phospholipase C-ac... |
antiviral innate immune response G protein-coupled receptor signaling pathway negative regulation of interleukin-6 production phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of interferon-alpha production positive regulation of osteoclast proliferation positive regulation of ... | cytosol; plasma membrane | bombesin receptor activity neuropeptide receptor activity | Homo sapiens | 3D-structure Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MPSKSLSNLS | MPSKSLSNLSVTTGANESGSVPEGWERDFLPASDGTTTELVIRCVIPSLYLLIITVGLLGNIMLVKIFITNSAMRSVPNIFISNLAAGDLLLLLTCVPVDASRYFFDEWMFGKVGCKLIPVIQLTSVGVSVFTLTALSADRYRAIVNPMDMQTSGALLRTCVKAMGIWVVSVLLAVPEAVFSEVARISSLDNSSFTACIPYPQTDELHPKIHSVLIFLVYFLIPLAIISIYYYHIAKTLIKSAHNLPGEYNEHTKKQMETRKRLAKIVLVFVGCFIFCWFPNHILYMYRSFNYNEIDPSLGHMIVTLVARVLSFGNSCVN... | antiviral innate immune response G protein-coupled receptor signaling pathway negative regulation of interleukin-6 production phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of interferon-alpha production positive regulation of osteoclast proliferation positive regulation of ... |
embryonic organ development hippo signaling positive regulation of cell growth positive regulation of DNA-templated transcription positive regulation of miRNA transcription positive regulation of transcription by RNA polymerase II protein-containing complex assembly regulation of transcription by RNA polymerase II | chromatin; nucleoplasm; nucleus; TEAD-YAP complex; transcription regulator complex | DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Homo sapiens | 3D-structure Acetylation Activator Alternative splicing Direct protein sequencing Disease variant DNA-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MEPSSWSGSE | MEPSSWSGSESPAENMERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLKDQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAPGFWPGMIQTGQPGSSQDVKPFVQQAYPIQPAVTAPIPGFEPASAPAPSVPAWQGRSIGTTKLRLVEFSAFLEQQRDPDSYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDAGAFYGVTSQYESSENMTV... | embryonic organ development hippo signaling positive regulation of cell growth positive regulation of DNA-templated transcription positive regulation of miRNA transcription positive regulation of transcription by RNA polymerase II protein-containing complex assembly regulation of transcription by RNA polymerase II chro... |
base-excision repair cell redox homeostasis cellular response to hydrogen peroxide DNA catabolic process DNA demethylation DNA recombination DNA repair negative regulation of smooth muscle cell migration positive regulation of G1/S transition of mitotic cell cycle positive regulation of transcription by RNA polymerase ... | centrosome; cytoplasm; endoplasmic reticulum; mitochondrion; nuclear speck; nucleolus; nucleoplasm; nucleus; perinuclear region of cytoplasm; transcription regulator complex | 3'-5' exonuclease activity 3'-5'-DNA exonuclease activity chromatin DNA binding class II DNA-(apurinic or apyrimidinic site) endonuclease activity damaged DNA binding DNA binding DNA-(abasic site) binding DNA-(apurinic or apyrimidinic site) endonuclease activity double-stranded DNA 3'-5' DNA exonuclease activity double... | Mus musculus | 3D-structure Acetylation Activator Cleavage on pair of basic residues Cytoplasm Direct protein sequencing Disulfide bond DNA damage DNA recombination DNA repair DNA-binding Endonuclease Endoplasmic reticulum Exonuclease Hydrolase Magnesium Metal-binding Mitochondrion Nuclease Nucleus Phosphoprotein Reference proteome R... | MPKRGKKAAA | MPKRGKKAAADDGEEPKSEPETKKSKGAAKKTEKEAAGEGPVLYEDPPDQKTSPSGKSATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLTHQYWSAPSDKEGYSGVGLLSRQCPLKVSYGIGEEEHDQEGRVIVAEFESFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKDLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTAYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL | base-excision repair cell redox homeostasis cellular response to hydrogen peroxide DNA catabolic process DNA demethylation DNA recombination DNA repair negative regulation of smooth muscle cell migration positive regulation of G1/S transition of mitotic cell cycle positive regulation of transcription by RNA polymerase ... |
adult locomotory behavior anterior/posterior pattern specification DNA-templated transcription embryonic forelimb morphogenesis embryonic skeletal system morphogenesis hindlimb morphogenesis mammary gland development negative regulation of transcription by RNA polymerase II peripheral nervous system neuron development ... | chromatin; nucleolus; nucleoplasm; nucleus | DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specif... | Homo sapiens | Developmental protein DNA-binding Homeobox Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MLGGSAGRLK | MLGGSAGRLKMSSSGTLSNYYVDSLIGHEGDEVFAARFGPPGPGAQGRPAGVADGPAATAAEFASCSFAPRSAVFSASWSAVPSQPPAAAAMSGLYHPYVPPPPLAASASEPGRYVRSWMEPLPGFPGGAGGGGGGGGGGPGRGPSPGPSGPANGRHYGIKPETRAAPAPATAASTTSSSSTSLSSSSKRTECSVARESQGSSGPEFSCNSFLQEKAAAATGGTGPGAGIGAATGTGGSSEPSACSDHPIPGCSLKEEEKQHSQPQQQQLDPNNPAANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVAR... | adult locomotory behavior anterior/posterior pattern specification DNA-templated transcription embryonic forelimb morphogenesis embryonic skeletal system morphogenesis hindlimb morphogenesis mammary gland development negative regulation of transcription by RNA polymerase II peripheral nervous system neuron development ... |
adult locomotory behavior anterior/posterior pattern specification DNA-templated transcription embryonic forelimb morphogenesis embryonic skeletal system development embryonic skeletal system morphogenesis forelimb morphogenesis hindlimb morphogenesis mammary gland development negative regulation of transcription by RN... | nucleolus; nucleoplasm; nucleus | DNA binding DNA-binding transcription factor activity DNA-binding transcription repressor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA bindi... | Mus musculus | Developmental protein DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation | MSSSGTLSNY | MSSSGTLSNYYVDSLIGHEGDEVFAARFGPPGPGTQGRPAGVADGPAAATAEFASCSFAPKSSVFSASWSAVAAQPPAAATMSGLYHPYVSPPPLAAAEPGRYVRSWMEPLPGFPGGAGGGGGSGGGGGGGPGPVPSPGGPANGRHYGIKPETGAAPAPAAASTSSSSSTSSSSSSKRTECSAARESQGSGGPEFPCNSFLRDKAAAATGNGPGVGIGTGPGAVGSSEPSACSDHPSPGCSLKEEEKQPPQPPQQQLDPNNPAANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARILNLTERQVKIWF... | adult locomotory behavior anterior/posterior pattern specification DNA-templated transcription embryonic forelimb morphogenesis embryonic skeletal system development embryonic skeletal system morphogenesis forelimb morphogenesis hindlimb morphogenesis mammary gland development negative regulation of transcription by RN... |
adult locomotory behavior anterior/posterior pattern specification embryonic limb morphogenesis embryonic skeletal system morphogenesis forelimb morphogenesis hindlimb morphogenesis negative regulation of cell cycle neuromuscular process peripheral nervous system neuron development proximal/distal pattern formation reg... | chromatin; cytoplasmic ribonucleoprotein granule; cytosol; nucleoplasm; nucleus; transcription repressor complex | chromatin binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Homo sapiens | Developmental protein Disease variant DNA-binding Homeobox Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MSFPNSSPAA | MSFPNSSPAANTFLVDSLISACRSDSFYSSSASMYMPPPSADMGTYGMQTCGLLPSLAKREVNHQNMGMNVHPYIPQVDSWTDPNRSCRIEQPVTQQVPTCSFTTNIKEESNCCMYSDKRNKLISAEVPSYQRLVPESCPVENPEVPVPGYFRLSQTYATGKTQEYNNSPEGSSTVMLQLNPRGAAKPQLSAAQLQMEKKMNEPVSGQEPTKVSQVESPEAKGGLPEERSCLAEVSVSSPEVQEKESKEEIKSDTPTSNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRMK... | adult locomotory behavior anterior/posterior pattern specification embryonic limb morphogenesis embryonic skeletal system morphogenesis forelimb morphogenesis hindlimb morphogenesis negative regulation of cell cycle neuromuscular process peripheral nervous system neuron development proximal/distal pattern formation reg... |
adult locomotory behavior anterior/posterior pattern specification embryonic limb morphogenesis embryonic skeletal system morphogenesis forelimb morphogenesis hindlimb morphogenesis neuromuscular process peripheral nervous system neuron development positive regulation of transcription by RNA polymerase II proximal/dist... | cytoplasmic ribonucleoprotein granule; cytosol; nucleoplasm; nucleus | chromatin binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription reg... | Mus musculus | Developmental protein DNA-binding Homeobox Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MSFPNSSPAA | MSFPNSSPAANTFLVDSLISACRSDSFYSSSASMYMPPPSADMGTYGMQTCGLLPSLAKREVNHQNMGMNVHPYIPQVDSWTDPNRSCRIEQPVTQQVPTCSFTANIKEESNCCMYSDKRNKLISAEVPSYQRLVPESCPVENPEVPVPGYFRLSQTYATGKTQEYNNSPEGSSTVMLQLNPRGAAKPQLSAAQLQMEKKMNESASGQEPTKVSQVESPEAKGGLPEDRSCLAEVSVSSPEVQEKESKEEIKSDTPTSNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRMK... | adult locomotory behavior anterior/posterior pattern specification embryonic limb morphogenesis embryonic skeletal system morphogenesis forelimb morphogenesis hindlimb morphogenesis neuromuscular process peripheral nervous system neuron development positive regulation of transcription by RNA polymerase II proximal/dist... |
intracellular protein transmembrane transport protein import protein targeting protein transport by the Sec complex | cell envelope Sec protein transport complex; cytoplasm; membrane raft; plasma membrane | ATP binding metal ion binding protein-exporting ATPase activity | Bacillus subtilis | 3D-structure ATP-binding Cell membrane Cytoplasm Membrane Metal-binding Nucleotide-binding Protein transport Reference proteome Translocase Translocation Transport Zinc | MLGILNKMFD | MLGILNKMFDPTKRTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMFPFKVQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHVVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANAFVRTLKAEKDYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSFT... | intracellular protein transmembrane transport protein import protein targeting protein transport by the Sec complex cell envelope Sec protein transport complex; cytoplasm; membrane raft; plasma membrane ATP binding metal ion binding protein-exporting ATPase activity Bacillus subtilis 3D-structure ATP-binding Cell membr... |
axon extension canonical Wnt signaling pathway cell fate commitment germ-line stem-cell niche homeostasis muscle organ development neuron differentiation open tracheal system development positive regulation of JNK cascade segment polarity determination | extracellular region; extracellular space | cytokine activity frizzled binding signaling receptor binding | Drosophila melanogaster | Developmental protein Disulfide bond Extracellular matrix Glycoprotein Lipoprotein Reference proteome Secreted Segmentation polarity protein Signal Wnt signaling pathway | MWKIHNKLLI | MWKIHNKLLIYILWIMEIRLVSSFTSVMLCGRIPGLTPGQRNMCREMPDALIALGEGHQLGAQECQHQFRGHRWNCSEVWQRNVFAHVIPTASREAAYTYAIASAGAAYAVTAACARGNISTCGCDVRHKATPTGGGTPDEPWKWGGCSADVDFGMRYARRFMDARELERDSRTLMNLHNNRAGRTLVKKMLRTDCKCHGVSGSCVMKTCWKSLPPFRLVGDRLMLKYQKAKTVQAVKGKRGLRLVLSRKKHAGTARAQKPVLDWPKRMELIYLEASPNYCERSLQTGSQGTSGRTCQRTGHGPQSCDLLCCGRGHNTQH... | axon extension canonical Wnt signaling pathway cell fate commitment germ-line stem-cell niche homeostasis muscle organ development neuron differentiation open tracheal system development positive regulation of JNK cascade segment polarity determination extracellular region; extracellular space cytokine activity frizzle... |
axon extension axon guidance canonical Wnt signaling pathway cell fate commitment chemorepulsion of axon dendrite guidance determination of muscle attachment site negative chemotaxis neuron differentiation positive regulation of axon extension positive regulation of axon guidance salivary gland morphogenesis Wnt signal... | dendrite; extracellular region; extracellular space | cytokine activity frizzled binding receptor ligand activity signaling receptor binding | Drosophila melanogaster | Developmental protein Disulfide bond Extracellular matrix Glycoprotein Lipoprotein Reference proteome Secreted Signal Wnt signaling pathway | MSCYRKRHFL | MSCYRKRHFLLWLLRAVCMLHLTARGAYATVGLQGVPTWIYLGLKSPFIEFGNQVEQLANSSIPLNMTKDEQANMHQEGLRKLGTFIKPVDLRDSETGFVKADLTKRLVFDRPNNITSRPIHPIQEEMDQKQIILLDEDTDENGLPASLTDEDRKFIVPMALKNISPDPRWAATTPSPSALQPNAKAISTIVPSPLAQVEGDPTSNIDDLKKHILFLHNMTKTNSNFESKFVKFPSLQKDKAKTSGAGGSPPNPKRPQRPIHQYSAPIAPPTPKVPAPDGGGVGGAAYNPGEQPIGGYYQNEELANNQSLLKPTDTDSHP... | axon extension axon guidance canonical Wnt signaling pathway cell fate commitment chemorepulsion of axon dendrite guidance determination of muscle attachment site negative chemotaxis neuron differentiation positive regulation of axon extension positive regulation of axon guidance salivary gland morphogenesis Wnt signal... |
alcohol metabolic process ethanol oxidation retinoic acid metabolic process retinol metabolic process secondary alcohol metabolic process | cytosol | alcohol dehydrogenase (NAD+) activity alcohol dehydrogenase activity, zinc-dependent butanol dehydrogenase activity NAD-retinol dehydrogenase activity zinc ion binding | Macaca mulatta | Acetylation Cytoplasm Metal-binding NAD Oxidoreductase Phosphoprotein Reference proteome Zinc | MSTAGKVIKC | MSTAGKVIKCKAAVLWEVMKPFSIEDVEVAPPKAYEVRIKMVTVGICGTDDHVVSGTMVTPLPVILGHEAAGIVESVGEGVTTVEPGDKVIPLALPQCGKCRICKTPERNYCLKNDVSNPRGTLQDGTSRFTCRGKPIHHFLGVSTFSQYTVVDENAVAKIDAASPMEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAVY... | alcohol metabolic process ethanol oxidation retinoic acid metabolic process retinol metabolic process secondary alcohol metabolic process cytosol alcohol dehydrogenase (NAD+) activity alcohol dehydrogenase activity, zinc-dependent butanol dehydrogenase activity NAD-retinol dehydrogenase activity zinc ion binding Macaca... |
calcineurin-mediated signaling penetration of zona pellucida | calcineurin complex; cytosol; mitochondrion; sperm flagellum; sperm midpiece; sperm mitochondrial sheath | calcium ion binding calcium-dependent protein serine/threonine phosphatase regulator activity phosphatase binding | Rattus norvegicus | Calcium Lipoprotein Metal-binding Mitochondrion Myristate Reference proteome Repeat | MGNEASYHSE | MGNEASYHSEMGTHFDHDEIKRLGRSFKKMDLDKSGSLSVDEFMSLPELQQNPLVGRVIDIFDTDGNGEVDFREFIVGTSQFSVKGDEEQKLRFAFRIYDMDNDGFISNGELFQVLKMMVGNNLKDWQLQQLVDKSILVLDKDGDGRISFEEFRDVVRTMEIHKKLVVFVDHGQED | calcineurin-mediated signaling penetration of zona pellucida calcineurin complex; cytosol; mitochondrion; sperm flagellum; sperm midpiece; sperm mitochondrial sheath calcium ion binding calcium-dependent protein serine/threonine phosphatase regulator activity phosphatase binding Rattus norvegicus Calcium Lipoprotein Me... |
central nervous system development chloride transmembrane transport gamma-aminobutyric acid signaling pathway regulation of postsynaptic membrane potential synaptic transmission, GABAergic | chloride channel complex; dendrite membrane; GABA-A receptor complex; GABA-ergic synapse; neuron projection; postsynapse; postsynaptic specialization membrane; synapse | GABA-A receptor activity GABA-gated chloride ion channel activity inhibitory extracellular ligand-gated monoatomic ion channel activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | Rattus norvegicus | Cell membrane Chloride Chloride channel Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MVSVQKVPAI | MVSVQKVPAIVLCSGVSLALLHVLCLATCLNESPGQNSKDEKLCPENFTRILDSLLDGYDNRLRPGFGGPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTKGPEKSVEVPKESSSLVQYDLIGQTVSSETIKSITGEYIVMTVYFHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMD... | central nervous system development chloride transmembrane transport gamma-aminobutyric acid signaling pathway regulation of postsynaptic membrane potential synaptic transmission, GABAergic chloride channel complex; dendrite membrane; GABA-A receptor complex; GABA-ergic synapse; neuron projection; postsynapse; postsynap... |
cellular response to histamine chloride transmembrane transport gamma-aminobutyric acid signaling pathway inhibitory synapse assembly roof of mouth development signal transduction synaptic transmission, GABAergic | chloride channel complex; cytoplasmic vesicle membrane; GABA-A receptor complex; neuron projection; plasma membrane; postsynaptic membrane; synapse | GABA-A receptor activity GABA-gated chloride ion channel activity identical protein binding neurotransmitter receptor activity | Homo sapiens | 3D-structure Alternative splicing Cell membrane Chloride Chloride channel Cytoplasmic vesicle Direct protein sequencing Disease variant Disulfide bond Epilepsy Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Tra... | MWGLAGGRLF | MWGLAGGRLFGIFSAPVLVAVVCCAQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLA... | cellular response to histamine chloride transmembrane transport gamma-aminobutyric acid signaling pathway inhibitory synapse assembly roof of mouth development signal transduction synaptic transmission, GABAergic chloride channel complex; cytoplasmic vesicle membrane; GABA-A receptor complex; neuron projection; plasma ... |
chloride transmembrane transport gamma-aminobutyric acid signaling pathway regulation of postsynaptic membrane potential response to xenobiotic stimulus synaptic transmission, GABAergic | chloride channel complex; dendrite membrane; GABA-A receptor complex; GABA-ergic synapse; microtubule cytoskeleton; neuron projection; nucleolus; postsynapse; postsynaptic membrane; synapse; synaptic membrane | chloride channel activity GABA-A receptor activity GABA-gated chloride ion channel activity inhibitory extracellular ligand-gated monoatomic ion channel activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | Rattus norvegicus | Cell membrane Chloride Chloride channel Disulfide bond Glycoprotein Ion channel Ion transport Lipoprotein Membrane Palmitate Postsynaptic cell membrane Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MAAKLLLLLC | MAAKLLLLLCLFSGLHARSRRVEEDDSEDSPSNQKWVLAPKSQDTDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAECQLQLHNFPMDAHACPLTFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDFMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTTLGITTVLTMTTLSTIARKSLPRVSYVTAMDLFV... | chloride transmembrane transport gamma-aminobutyric acid signaling pathway regulation of postsynaptic membrane potential response to xenobiotic stimulus synaptic transmission, GABAergic chloride channel complex; dendrite membrane; GABA-A receptor complex; GABA-ergic synapse; microtubule cytoskeleton; neuron projection;... |
ethanol catabolic process ethanol oxidation fatty acid omega-oxidation formaldehyde catabolic process positive regulation of blood pressure respiratory system process response to lipopolysaccharide response to nitrosative stress response to redox state retinoid metabolic process | cytosol; mitochondrion | alcohol dehydrogenase (NAD+) activity alcohol dehydrogenase activity, zinc-dependent fatty acid binding formaldehyde dehydrogenase activity identical protein binding S-(hydroxymethyl)glutathione dehydrogenase activity S-(hydroxymethyl)glutathione dehydrogenase NAD activity S-(hydroxymethyl)glutathione dehydrogenase NAD... | Mus musculus | Acetylation Cytoplasm Direct protein sequencing Lipid metabolism Metal-binding NAD Oxidoreductase Phosphoprotein Reference proteome Zinc | MANQVIRCKA | MANQVIRCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKILATAVCHTDAYTLSGADPEGCFPVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGKGLMPDGTSRFTCKGKSVFHFMGTSTFSEYTVVADISVAKIDPSAPLDKVCLLGCGISTGYGAAVNTAKVEPGSTCAVFGLGGVGLAVIMGCKVAGASRIIGIDINKDKFAKAKEFGASECISPQDFSKSIQEVLVEMTDGGVDYSFECIGNVKVMRSALEAAHKGWGVSVVVGVAASGEEISTRPFQLVTGRTWKGTAFG... | ethanol catabolic process ethanol oxidation fatty acid omega-oxidation formaldehyde catabolic process positive regulation of blood pressure respiratory system process response to lipopolysaccharide response to nitrosative stress response to redox state retinoid metabolic process cytosol; mitochondrion alcohol dehydroge... |
chemical synaptic transmission chloride transmembrane transport gamma-aminobutyric acid signaling pathway signal transduction visual perception | chloride channel complex; GABA-A receptor complex; GABA-ergic synapse; neuron projection; plasma membrane; postsynaptic membrane; synapse | chloride channel activity GABA-A receptor activity neurotransmitter receptor activity protein domain specific binding transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | Homo sapiens | Alternative initiation Cell membrane Chloride Chloride channel Disulfide bond Glycoprotein Ion channel Ion transport Membrane Postsynaptic cell membrane Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MPYFTRLILF | MPYFTRLILFLFCLMVLVESRKPKRKRWTGQVEMPKPSHLYKKNLDVTKIRKGKPQQLLRVDEHDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSASNKSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITTVLTMTTIITGVNASMPRVSY... | chemical synaptic transmission chloride transmembrane transport gamma-aminobutyric acid signaling pathway signal transduction visual perception chloride channel complex; GABA-A receptor complex; GABA-ergic synapse; neuron projection; plasma membrane; postsynaptic membrane; synapse chloride channel activity GABA-A recep... |
binding of sperm to zona pellucida chaperone-mediated protein folding positive regulation of establishment of protein localization to telomere positive regulation of telomerase RNA localization to Cajal body positive regulation of telomere maintenance via telomerase protein folding protein stabilization scaRNA localiza... | acrosomal vesicle; cell body; centrosome; chaperonin-containing T-complex; Golgi apparatus; heterochromatin; microtubule; microtubule organizing center; pericentriolar material; zona pellucida receptor complex | ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone protein folding chaperone ubiquitin protein ligase binding unfolded protein binding | Rattus norvegicus | Acetylation ATP-binding Chaperone Cytoplasm Cytoskeleton Direct protein sequencing Nucleotide-binding Phosphoprotein Reference proteome | MEGPLSVFGD | MEGPLSVFGDRSTGEAIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIINTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAVKYTDIRGQPRYPVNSVNILKAHGRSQIESMLINGYALNCVVGSQGMLKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIA... | binding of sperm to zona pellucida chaperone-mediated protein folding positive regulation of establishment of protein localization to telomere positive regulation of telomerase RNA localization to Cajal body positive regulation of telomere maintenance via telomerase protein folding protein stabilization scaRNA localiza... |
actin cytoskeleton organization barbed-end actin filament capping | actin cortical patch; actin cytoskeleton; cellular bud neck; cellular bud tip; F-actin capping protein complex; incipient cellular bud site; mating projection tip; plasma membrane | actin filament binding | Saccharomyces cerevisiae | Acetylation Actin capping Actin-binding Direct protein sequencing Phosphoprotein Reference proteome | MSSSKFEEVI | MSSSKFEEVINKIINDSPPGELREVYDDLIKITSENSKNTILDAIENYNVQNCIPIEVNGNSVIISKYNKEGAKFFDPVNSVIFSVNHLERKGLDIEPYEFTHAKIEKGQLKELHDKLHEYLLQSFPGDVSFAVYPVPEEISKISIIIVSTKYNPNNFWNGHWRSSYIYDLETRELSGQISTQVHYYEDGNVSFQSGKDINQSNVDDVVCTIRDIETNFENDLDLSFFDLNEKQFKALRRRLPVTRSKINWGSAIGSYRLGKNAAEGK | actin cytoskeleton organization barbed-end actin filament capping actin cortical patch; actin cytoskeleton; cellular bud neck; cellular bud tip; F-actin capping protein complex; incipient cellular bud site; mating projection tip; plasma membrane actin filament binding Saccharomyces cerevisiae Acetylation Actin capping... |
ceramide biosynthetic process | acyl-CoA ceramide synthase complex; endoplasmic reticulum; endoplasmic reticulum membrane; nuclear periphery | sphingosine N-acyltransferase activity | Saccharomyces cerevisiae | Acetylation Endoplasmic reticulum Glycoprotein Lipid biosynthesis Lipid metabolism Membrane Phosphoprotein Reference proteome Transferase Transmembrane Transmembrane helix | MSTIKPSPSN | MSTIKPSPSNNNLKVRSRPRRKSSIGKIDLGDTVPSLGTMFETKESKTAAKRRMQRLSEATKNDSDLVKKIWFSFREISYRHAWIAPLMILIAVYSAYFTSGNTTKTNVLHRFVAVSYQIGDTNAYGKGINDLCFVFYYMIFFTFLREFLMDVVIRPFAIRLHVTSKHRIKRIMEQMYAIFYTGVSGPFGIYCMYHSDLWFFNTKAMYRTYPDFTNPFLFKVFYLGQAAFWAQQACILVLQLEKPRKDHNELTFHHIVTLLLIWSSYVFHFTKMGLPIYITMDVSDFLLSFSKTLNYLDSGLAFFSFAIFVVAWIYLRHY... | ceramide biosynthetic process acyl-CoA ceramide synthase complex; endoplasmic reticulum; endoplasmic reticulum membrane; nuclear periphery sphingosine N-acyltransferase activity Saccharomyces cerevisiae Acetylation Endoplasmic reticulum Glycoprotein Lipid biosynthesis Lipid metabolism Membrane Phosphoprotein Reference... |
cell fate commitment epidermal cell fate specification negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II spermatid development stem cell population maintenance | axon; nucleus; perikaryon | DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding zinc ion binding | Caenorhabditis elegans | Activator Cell projection Developmental protein DNA-binding Metal-binding Nucleus Reference proteome Repeat Transcription Transcription regulation Zinc Zinc-finger | MDYEGKPVEF | MDYEGKPVEFTLGTSSGGASLAPTSSTTAASIAPFSYNTSATNYYNTTPSSYPMFLNYQYAGGTTVTTDMDAFSGMDMSMNNGVFGTQNNPSYFYPTTQLNTYGYDTLAAATTASGITVNNNQLNVNIVQGNGTIVPQPITQNIISTVSNVQSSVPINNSQPLTPTGLAGCSTSSGSSSASSSSANSTSTPKNTISKANRSSGGANNSQFSTEDRECVNCGVHNTPLWRRDGSGNYLCNACGLYFKMNHHARPLVKPKKRQQNAQKRTGIECVNCRTNTTTLWRRNGEGHPVCNACGLYFKLHKVERPITMKKDGIQTRN... | cell fate commitment epidermal cell fate specification negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II spermatid development stem cell population maintenance axon; nucleus; perikaryon DNA-binding transcription factor activity, RNA polymerase II-specifi... |
base-excision repair nucleotide-excision repair involved in interstrand cross-link repair nucleotide-excision repair, DNA damage recognition UV-damage excision repair | nucleotide-excision repair factor 1 complex; nucleus | damaged DNA binding zinc ion binding | Saccharomyces cerevisiae | 3D-structure DNA damage DNA repair DNA-binding Metal-binding Nucleus Reference proteome Zinc Zinc-finger | MTPEQKAKLE | MTPEQKAKLEANRKLAIERLRKRGILSSDQLNRIESRNEPLKTRPLAVTSGSNRDDNAAAAVHVPNHNGQPSALANTNTNTTSLYGSGVVDGSKRDASVLDKRPTDRIRPSIRKQDYIEYDFATMQNLNGGYINPKDKLPNSDFTDDQEFESEFGSKKQKTLQDWKKEQLERKMLYENAPPPEHISKAPKCIECHINIEMDPVLHDVFKLQVCKQCSKEHPEKYALLTKTECKEDYFLTDPELNDEDLFHRLEKPNPHSGTFARMQLFVRCEVEAFAFKKWGGEEGLDEEWQRREEGKAHRREKKYEKKIKEMRLKTRAQ... | base-excision repair nucleotide-excision repair involved in interstrand cross-link repair nucleotide-excision repair, DNA damage recognition UV-damage excision repair nucleotide-excision repair factor 1 complex; nucleus damaged DNA binding zinc ion binding Saccharomyces cerevisiae 3D-structure DNA damage DNA repair DN... |
phosphorylation regulation of cell cycle | cytosol; nucleus; protein kinase CK2 complex | ATP binding protein serine kinase activity protein serine/threonine kinase activity | Zea mays | 3D-structure ATP-binding Kinase Nucleotide-binding Reference proteome Serine/threonine-protein kinase Transferase | MSKARVYADV | MSKARVYADVNVLRPKEYWDYEALTVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEKCIIKILKPVKKKKIKREIKILQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYVNNTDFKVLYPTLTDYDIRYYIYELLKALDYCHSQGIMHRDVKPHNVMIDHELRKLRLIDWGLAEFYHPGKEYNVRVASRYFKGPELLVDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNHDQLVKIAKVLGTDGLNVYLNKYRIELDPQLEALVGRHSRKPWLKFMNADNQHLVSPEAIDFLDKLLRYDHQERLTALEAMTHPYFQ... | phosphorylation regulation of cell cycle cytosol; nucleus; protein kinase CK2 complex ATP binding protein serine kinase activity protein serine/threonine kinase activity Zea mays 3D-structure ATP-binding Kinase Nucleotide-binding Reference proteome Serine/threonine-protein kinase Transferase MSKARVYADV MSKARVYADVNVLRPK... |
response to hermaphrodite contact vulval location Wnt signaling pathway | axon; cilium; cytoplasm; dendrite; neuronal cell body; non-motile cilium; nucleus; perikaryon; protein kinase CK2 complex | protein kinase regulator activity | Caenorhabditis elegans | Alternative splicing Behavior Cell projection Cilium Phosphoprotein Reference proteome Wnt signaling pathway | MSSSEEVSWI | MSSSEEVSWITWFCGLRGNEFFCEVDEEYIQDRFNLTGLNEQVPKYRQALDMILDLEPDDIEDNATNTDLVEQAAEMLYGLIHARYILTNRGISQMVEKWRDHDFGVCPRVYCENQPMLPIGLSDVPGEAMVKLYCPRCNDVFVPRSSRHQHTDGSYFGTGFPHMLFFVHPDLRPRRPVTQFVPKLYGFKIHPVAYGGQEGNSGGNTANNVAAAQNNTTPAGQQSGGQFNNYGL | response to hermaphrodite contact vulval location Wnt signaling pathway axon; cilium; cytoplasm; dendrite; neuronal cell body; non-motile cilium; nucleus; perikaryon; protein kinase CK2 complex protein kinase regulator activity Caenorhabditis elegansAlternative splicing Behavior Cell projection Cilium Phosphoprotein Re... |
cell cycle cellular response to chemokine endoderm formation negative regulation of cell adhesion negative regulation of cell population proliferation negative regulation of MAP kinase activity negative regulation of MAPK cascade negative regulation of meiotic cell cycle negative regulation of monocyte chemotaxis negat... | cytoplasm; nucleus | MAP kinase tyrosine phosphatase activity MAP kinase tyrosine/serine/threonine phosphatase activity mitogen-activated protein kinase binding myosin phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity protein tyrosine/serine/threonine phosphatase activity protein tyros... | Homo sapiens | 3D-structure Cell cycle Hydrolase Nucleus Phosphoprotein Protein phosphatase Reference proteome Stress response | MVMEVGTLDA | MVMEVGTLDAGGLRALLGERAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAMGLEHIVPNAELRGRLLAGAYHAVVLLDERSAALDGAKRDGTLALAAGALCREARAAQVFFLKGGYEAFSASCPELCSKQSTPMGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAPHCSAE... | cell cycle cellular response to chemokine endoderm formation negative regulation of cell adhesion negative regulation of cell population proliferation negative regulation of MAP kinase activity negative regulation of MAPK cascade negative regulation of meiotic cell cycle negative regulation of monocyte chemotaxis negat... |
cell cycle cellular response to chemokine endoderm formation intracellular signal transduction negative regulation of apoptotic process negative regulation of cell adhesion negative regulation of cell population proliferation negative regulation of DNA biosynthetic process negative regulation of ERK1 and ERK2 cascade n... | cytoplasm; nucleus | growth factor binding MAP kinase tyrosine phosphatase activity MAP kinase tyrosine/serine/threonine phosphatase activity mitogen-activated protein kinase binding myosin phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity protein tyrosine/serine/threonine phosphatase ... | Mus musculus | Cell cycle Hydrolase Nucleus Phosphoprotein Protein phosphatase Reference proteome | MVMEVGILDA | MVMEVGILDAGGLRALLREGAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAMGLEHIVPNAELRGRLLAGAYHAVVLLDERSASLDGAKRDGTLALAAGALCREARSTQVFFLQGGYEAFSASCPELCSKQSTPTGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILSFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKDAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAPHCSAE... | cell cycle cellular response to chemokine endoderm formation intracellular signal transduction negative regulation of apoptotic process negative regulation of cell adhesion negative regulation of cell population proliferation negative regulation of DNA biosynthetic process negative regulation of ERK1 and ERK2 cascade n... |
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting serotonin receptor signaling pathway chemical synaptic transmission G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger intestine smooth muscle contraction regulation of behavio... | dendrite; glutamatergic synapse; neuronal dense core vesicle; plasma membrane | G protein-coupled serotonin receptor activity neurotransmitter receptor activity serotonin binding | Rattus norvegicus | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MSLPNQSLEG | MSLPNQSLEGLPQEASNRSLNATGAWDPEVLQALRISLVVVLSIITLATVLSNAFVLTTILLTKKLHTPANYLIGSLATTDLLVSILVMPISIAYTTTRTWNFGQILCDIWVSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAAVWAISICISIPPLFWRQATAHEEMSDCLVNTSQISYTIYSTCGAFYIPSILLIILYGRIYVAARSRILNPPSLYGKRFTTAQLITGSAGSSLCSLNPSLHESHTHTVGSPLFFNQVKIKLADSILERKRISAARERKATKTLGIILGAFIICWLPFFVVSLV... | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting serotonin receptor signaling pathway chemical synaptic transmission G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger intestine smooth muscle contraction regulation of behavio... |
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting serotonin receptor signaling pathway chemical synaptic transmission G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | dendrite; plasma membrane; synapse | G protein-coupled receptor activity G protein-coupled serotonin receptor activity neurotransmitter receptor activity serotonin binding | Homo sapiens | 3D-structure Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MNITNCTTEA | MNITNCTTEASMAIRPKTITEKMLICMTLVVITTLTTLLNLAVIMAIGTTKKLHQPANYLICSLAVTDLLVAVLVMPLSIIYIVMDRWKLGYFLCEVWLSVDMTCCTCSILHLCVIALDRYWAITNAIEYARKRTAKRAALMILTVWTISIFISMPPLFWRSHRRLSPPPSQCTIQHDHVIYTIYSTLGAFYIPLTLILILYYRIYHAAKSLYQKRGSSRHLSNRSTDSQNSFASCKLTQTFCVSDFSTSDPTTEFEKFHASIRIPPFDNDLDHPGERQQISSTRERKAARILGLILGAFILSWLPFFIKELIVGLSIYT... | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting serotonin receptor signaling pathway chemical synaptic transmission G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger dendrite; pl... |
creatine transmembrane transport embryonic brain development neurotransmitter transport nitrogen compound transport protein catabolic process sodium ion transmembrane transport | apical plasma membrane; glutamatergic synapse; plasma membrane; postsynaptic membrane; synapse | choline transmembrane transporter activity creatine transmembrane transporter activity creatine:sodium symporter activity gamma-aminobutyric acid:sodium:chloride symporter activity | Rattus norvegicus | Cell membrane Glycoprotein Ion transport Membrane Phosphoprotein Reference proteome Sodium Sodium transport Symport Transmembrane Transmembrane helix Transport | MAKKSAENGI | MAKKSAENGIYSVSGDEKKGPLIVSGPDGAPSKGDGPAGLGAPSSRLAVPPRETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFLEISLGQFMKAGSINVWNICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWATCGHTWNTPDCVEIFRHEDCANASLANLTCDQLADRRSPVIEFWENKVLRLSTGLEVPGALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLLVRGVLLPGALDGIIYYLKPDWSKLGSPQVWIDAGTQIFFSYAIG... | creatine transmembrane transport embryonic brain development neurotransmitter transport nitrogen compound transport protein catabolic process sodium ion transmembrane transport apical plasma membrane; glutamatergic synapse; plasma membrane; postsynaptic membrane; synapse choline transmembrane transporter activity creat... |
glycine import across plasma membrane glycine secretion, neurotransmission glycine transport negative regulation of NMDA glutamate receptor activity neurotransmitter uptake positive regulation of heme biosynthetic process positive regulation of hemoglobin biosynthetic process regulation of synaptic transmission, glycin... | apical plasma membrane; asymmetric synapse; basal plasma membrane; basolateral plasma membrane; dense core granule; endosome; hippocampal mossy fiber to CA3 synapse; lateral plasma membrane; membrane; parallel fiber to Purkinje cell synapse; plasma membrane; postsynaptic density; postsynaptic membrane; presynaptic memb... | glycine transmembrane transporter activity glycine:sodium symporter activity | Mus musculus | Alternative promoter usage Alternative splicing Amino-acid transport Cell membrane Membrane Neurotransmitter transport Phosphoprotein Reference proteome Symport Transmembrane Transmembrane helix Transport | MIGGDTRAAS | MIGGDTRAASAHPGMASAQGPVATPSPEQPFPGTTSVSLARPVLRVWHGAHSSGLLPNLIAQHSPAMAQNGAVPSEATKKDQNLTRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAYCNNPWNTPDCAGVLDASNLTNGSRPAALSGNLSHLFNYTLQRTSPSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWVVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRG... | glycine import across plasma membrane glycine secretion, neurotransmission glycine transport negative regulation of NMDA glutamate receptor activity neurotransmitter uptake positive regulation of heme biosynthetic process positive regulation of hemoglobin biosynthetic process regulation of synaptic transmission, glycin... |
glycine import across plasma membrane glycine secretion, neurotransmission glycine transport neurotransmitter uptake positive regulation of heme biosynthetic process positive regulation of hemoglobin biosynthetic process regulation of synaptic transmission, glycinergic sodium ion transmembrane transport synaptic transm... | apical plasma membrane; asymmetric synapse; basal plasma membrane; basolateral plasma membrane; dense core granule; endosome; hippocampal mossy fiber to CA3 synapse; lateral plasma membrane; parallel fiber to Purkinje cell synapse; plasma membrane; postsynaptic density; postsynaptic membrane; presynaptic membrane; syna... | glycine transmembrane transporter activity glycine:sodium symporter activity | Rattus norvegicus | Alternative promoter usage Amino-acid transport Cell membrane Glycoprotein Membrane Neurotransmitter transport Phosphoprotein Reference proteome Symport Transmembrane Transmembrane helix Transport | MAVAHGPVAT | MAVAHGPVATSSPEQNGAVPSEATKKDQNLTRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLVFCGIPLFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAYCNNPWNTPDCAGVLDASNLTNGSRPTALSGNLSHLFNYTLQRTSPSEEYWRLYVLKLSDDIGDFGEVRLPLLGCLGVSWVVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLEGAFTGIMYYLTPKWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKF... | glycine import across plasma membrane glycine secretion, neurotransmission glycine transport neurotransmitter uptake positive regulation of heme biosynthetic process positive regulation of hemoglobin biosynthetic process regulation of synaptic transmission, glycinergic sodium ion transmembrane transport synaptic transm... |
L-alpha-amino acid transmembrane transport neurotransmitter transport neutral amino acid transport proline transmembrane transport proline transport protein catabolic process sodium ion transmembrane transport | glutamatergic synapse; presynaptic membrane; Schaffer collateral - CA1 synapse; synapse; synaptic vesicle membrane | L-proline transmembrane transporter activity proline:sodium symporter activity | Rattus norvegicus | Amino-acid transport Cell membrane Glycoprotein Membrane Neurotransmitter transport Phosphoprotein Reference proteome Symport Synapse Transmembrane Transmembrane helix Transport | MKKLQEAHLR | MKKLQEAHLRKPVTPDLLMTPSDQGDVDLDVDFAADRGNWTGKLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAFLVPYFLMLAICGIPLFFLELSLGQFSSLGPLAVWKISPLFKGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSNLPWEHCGNWWNTERCLEHRGPKDGNGALPLNLSSTVSPSEEYWSRYVLHIQGSQGIGRPGEIRWNLCLCLLLAWVIVFLCILKGVKSSGKVVYFTATFPYLILLMLLVRGVTLPGAWKGIQFYLTPQFHHLLSSKVWIEAALQIFYSLGVGFGGLLTFASYNTFHQNIY... | L-alpha-amino acid transmembrane transport neurotransmitter transport neutral amino acid transport proline transmembrane transport proline transport protein catabolic process sodium ion transmembrane transport glutamatergic synapse; presynaptic membrane; Schaffer collateral - CA1 synapse; synapse; synaptic vesicle memb... |
cellular response to peptide hormone stimulus cellular response to starvation negative regulation of gene expression negative regulation of transcription by RNA polymerase II neuron apoptotic process positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II protein-con... | chromatin; dendrite; Mad-Max complex; MLL1 complex; Myc-Max complex; nucleus; PML body; protein-DNA complex; RNA polymerase II transcription regulator complex | DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor binding DNA-binding transcription repressor activity, RNA polymerase II-specific E-box binding identical protein binding protein dimerization activity protein-cont... | Mus musculus | 3D-structure Acetylation Activator Alternative splicing Cell projection DNA-binding Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation | MSDNDDIEVE | MSDNDDIEVESDEEQPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQVRALEKARSSAQLQTNYPSSDNSLYTNAKGGTISAFDGGSDSSSESEPEEPQSRKKLRMEAS | cellular response to peptide hormone stimulus cellular response to starvation negative regulation of gene expression negative regulation of transcription by RNA polymerase II neuron apoptotic process positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II protein-con... |
cell redox homeostasis | cytoplasm | flavin adenine dinucleotide binding trypanothione-disulfide reductase (NADP) activity | Trypanosoma cruzi | 3D-structure Cytoplasm Disulfide bond FAD Flavoprotein NADP Oxidoreductase Redox-active center | MMSKIFDLVV | MMSKIFDLVVIGAGSGGLEAAWNAATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEFDRTTLRAEWKKLIAVKDEAVLNINKSYEEMFRDTEGLEFFLGWGSLESKNVVNVRESADPASAVKERLETENILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNADGSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGVMIKNGGVQVDEYSRTNVS... | cell redox homeostasis cytoplasm flavin adenine dinucleotide binding trypanothione-disulfide reductase (NADP) activity Trypanosoma cruzi3D-structure Cytoplasm Disulfide bond FAD Flavoprotein NADP Oxidoreductase Redox-active center MMSKIFDLVV MMSKIFDLVVIGAGSGGLEAAWNAATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESA... |
protein processing involved in protein targeting to mitochondrion signal peptide processing | mitochondrial inner membrane; mitochondrial inner membrane peptidase complex; mitochondrion | endopeptidase activity serine-type endopeptidase activity | Saccharomyces cerevisiae | Direct protein sequencing Hydrolase Membrane Mitochondrion Mitochondrion inner membrane Protease Reference proteome | MTVGTLPIWS | MTVGTLPIWSKTFSYAIRSLCFLHIIHMYAYEFTETRGESMLPTLSATNDYVHVLKNFQNGRGIKMGDCIVALKPTDPNHRICKRVTGMPGDLVLVDPSTIVNYVGDVLVDEERFGTYIKVPEGHVWVTGDNLSHSLDSRTYNALPMGLIMGKIVAANNFDKPFWDGSIRNIWGFKWINNTFLDVQAKSN | protein processing involved in protein targeting to mitochondrion signal peptide processing mitochondrial inner membrane; mitochondrial inner membrane peptidase complex; mitochondrion endopeptidase activity serine-type endopeptidase activity Saccharomyces cerevisiae Direct protein sequencing Hydrolase Membrane Mitocho... |
signal peptide processing | plasma membrane | serine-type endopeptidase activity | Bacillus subtilis | Cell membrane Hydrolase Membrane Protease Reference proteome Transmembrane Transmembrane helix | MKSENVSKKK | MKSENVSKKKSILEWAKAIVIAVVLALLIRNFIFAPYVVDGDSMYPTLHNRERVFVNMTVKYIGEFDRGDIVVLNGDDVHYVKRIIGLPGDTVEMKNDQLYINGKKVDEPYLAANKKRAKQDGFDHLTDDFGPVKVPDNKYFVMGDNRRNSMDSRNGLGLFTKKQIAGTSKFVFYPFNEMRKTN | signal peptide processing plasma membrane serine-type endopeptidase activity Bacillus subtilis Cell membrane Hydrolase Membrane Protease Reference proteome Transmembrane Transmembrane helix MKSENVSKKK MKSENVSKKKSILEWAKAIVIAVVLALLIRNFIFAPYVVDGDSMYPTLHNRERVFVNMTVKYIGEFDRGDIVVLNGDDVHYVKRIIGLPGDTVEMKNDQLYINGKKVDEPYLAANKKRA... |
arginine catabolic process intracellular pH elevation | cytosol | arginine decarboxylase activity pyridoxal phosphate binding | Escherichia coli | 3D-structure Cytoplasm Decarboxylase Direct protein sequencing Lyase Pyridoxal phosphate Reference proteome | MKVLIVESEF | MKVLIVESEFLHQDTWVGNAVERLADALSQQNVTVIKSTSFDDGFAILSSNEAIDCLMFSYQMEHPDEHQNVRQLIGKLHERQQNVPVFLLGDREKALAAMDRDLLELVDEFAWILEDTADFIAGRAVAAMTRYRQQLLPPLFSALMKYSDIHEYSWAAPGHQGGVGFTKTPAGRFYHDYYGENLFRTDMGIERTSLGSLLDHTGAFGESEKYAARVFGADRSWSVVVGTSGSNRTIMQACMTDNDVVVVDRNCHKSIEQGLMLTGAKPVYMVPSRNRYGIIGPIYPQEMQPETLQKKISESPLTKDKAGQKPSYCVVTN... | arginine catabolic process intracellular pH elevation cytosol arginine decarboxylase activity pyridoxal phosphate binding Escherichia coli 3D-structure Cytoplasm Decarboxylase Direct protein sequencing Lyase Pyridoxal phosphate Reference proteome MKVLIVESEF MKVLIVESEFLHQDTWVGNAVERLADALSQQNVTVIKSTSFDDGFAILSSNEAIDCLMFSYQ... |
DNA replication DNA-templated DNA replication | DNA polymerase III complex; DNA polymerase III, clamp loader complex; replisome | DNA binding DNA-directed DNA polymerase activity | Escherichia coli | 3D-structure Direct protein sequencing DNA replication DNA-directed DNA polymerase Nucleotidyltransferase Reference proteome Transferase | MIRLYPEQLR | MIRLYPEQLRAQLNEGLRAAYLLLGNDPLLLQESQDAVRQVAAAQGFEEHHTFSIDPNTDWNAIFSLCQAMSLFASRQTLLLLLPENGPNAAINEQLLTLTGLLHDDLLLIVRGNKLSKAQENAAWFTALANRSVQVTCQTPEQAQLPRWVAARAKQLNLELDDAANQVLCYCYEGNLLALAQALERLSLLWPDGKLTLPRVEQAVNDAAHFTPFHWVDALLMGKSKRALHILQQLRLEGSEPVILLRTLQRELLLLVNLKRQSAHTPLRALFDKHRVWQNRRGMMGEALNRLSQTQLRQAVQLLTRTELTLKQDYGQSV... | DNA replication DNA-templated DNA replication DNA polymerase III complex; DNA polymerase III, clamp loader complex; replisome DNA binding DNA-directed DNA polymerase activity Escherichia coli 3D-structure Direct protein sequencing DNA replication DNA-directed DNA polymerase Nucleotidyltransferase Reference proteome Tra... |
cellular response to estradiol stimulus cellular response to leukemia inhibitory factor cerebellum development forebrain development G protein-coupled receptor signaling pathway glutamate receptor signaling pathway neuropeptide signaling pathway response to starvation spermatogenesis T cell differentiation | membrane; neuron projection; plasma membrane | neuropeptide binding somatostatin receptor activity | Rattus norvegicus | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MFPNGTAPSP | MFPNGTAPSPTSSPSSSPGGCGEGVCSRGPGSGAADGMEEPGRNSSQNGTLSEGQGSAILISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSVILGYANSCANP... | cellular response to estradiol stimulus cellular response to leukemia inhibitory factor cerebellum development forebrain development G protein-coupled receptor signaling pathway glutamate receptor signaling pathway neuropeptide signaling pathway response to starvation spermatogenesis T cell differentiation membrane; ne... |
calcium-mediated signaling G protein-coupled adenosine receptor signaling pathway G protein-coupled receptor signaling pathway histamine secretion by mast cell mast cell degranulation mucus secretion negative regulation of cell migration negative regulation of cell population proliferation phosphatidylinositol 3-kinase... | dendrite; neuromuscular junction; plasma membrane; presynaptic membrane; Schaffer collateral - CA1 synapse; synapse | G protein-coupled adenosine receptor activity | Rattus norvegicus | Alternative splicing Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MKANNTTTSA | MKANNTTTSALWLQITYITMEAAIGLCAVVGNMLVIWVVKLNRTLRTTTFYFIVSLALADIAVGVLVIPLAIAVSLEVQMHFYACLFMSCVLLVFTHASIMSLLAIAVDRYLRVKLTVRYRTVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKVTLELSQNSSTLSCHFRSVVGLDYMVFFSFITWILIPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFLFALCWLPLSIINFVSYFNVKIPEIAMCLGILLSHANSMMNPIVYACKIKKFKETYFVILRACRLCQTSDSLDSNLEQTTE | calcium-mediated signaling G protein-coupled adenosine receptor signaling pathway G protein-coupled receptor signaling pathway histamine secretion by mast cell mast cell degranulation mucus secretion negative regulation of cell migration negative regulation of cell population proliferation phosphatidylinositol 3-kinase... |
cell migration cell-matrix adhesion endosome to melanosome transport epithelial cell differentiation negative regulation of epithelial cell migration pigment cell differentiation pigment granule maturation pigmentation positive regulation of cell adhesion positive regulation of endocytosis positive regulation of integr... | cell surface; endosome lumen; endosome membrane; extracellular exosome; extracellular space; late endosome; late endosome membrane; lysosomal membrane; lysosome; melanosome; multivesicular body membrane; multivesicular body, internal vesicle; plasma membrane; protein-containing complex | protein-containing complex binding | Rattus norvegicus | Cell membrane Direct protein sequencing Endosome Glycoprotein Lipoprotein Lysosome Membrane Palmitate Protein transport Reference proteome Secreted Transmembrane Transmembrane helix Transport | MAVEGGMKCV | MAVEGGMKCVKFLLYVLLLAFCACAVGLIAIGVAVQVVLKQAITHETTAGSLLPVVIIAVGAFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAVAIAGYVFRDQVKSEFSKSFQKQMQNYLTDNKTATILDKLQKENKCCGASNYTDWERIPGMAKDRVPDSCCINITVGCGNDFKESTIHTQGCVETIAAWLRKNVLLVAGAALGIAFVEVLGIIFSCCLVKSIRSGYEVM | cell migration cell-matrix adhesion endosome to melanosome transport epithelial cell differentiation negative regulation of epithelial cell migration pigment cell differentiation pigment granule maturation pigmentation positive regulation of cell adhesion positive regulation of endocytosis positive regulation of integr... |
androgen catabolic process androgen metabolic process C21-steroid hormone metabolic process calcineurin-mediated signaling estrogen biosynthetic process female genitalia development female gonad development mammary gland development negative regulation of bone resorption negative regulation of chronic inflammatory resp... | axon terminus; dendritic spine; endoplasmic reticulum; endoplasmic reticulum membrane; neuronal cell body; synaptic vesicle; terminal bouton | aromatase activity heme binding iron ion binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | Mus musculus | Endoplasmic reticulum Heme Iron Lipid metabolism Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Reference proteome Transmembrane Transmembrane helix | MFLEMLNPMQ | MFLEMLNPMQYNVTIMVPETVTVSAMPLLLIMGLLLLIWNCESSSSIPGPGYCLGIGPLISHGRFLWMGIGSACNYYNKMYGEFMRVWISGEETLIISKSSSMFHVMKHSHYISRFGSKRGLQCIGMHENGIIFNNNPSLWRTIRPFFMKALTGPGLVRMVEVCVESIKQHLDRLGEVTDTSGYVDVLTLMRHIMLDTSNMLFLGIPLDESAIVKKIQGYFNAWQALLIKPNIFFKISWLYRKYERSVKDLKDEIAVLVEKKRHKVSTAEKLEDCMDFATDLIFAERRGDLTKENVNQCILEMLIAAPDTMSVTLYFMLL... | androgen catabolic process androgen metabolic process C21-steroid hormone metabolic process calcineurin-mediated signaling estrogen biosynthetic process female genitalia development female gonad development mammary gland development negative regulation of bone resorption negative regulation of chronic inflammatory resp... |
de novo' AMP biosynthetic process AMP biosynthetic process AMP salvage aspartate metabolic process IMP metabolic process purine nucleotide metabolic process | cytoplasm; membrane | actin filament binding adenylosuccinate synthase activity GTP binding GTPase activity identical protein binding magnesium ion binding | Mus musculus | 3D-structure Alternative splicing Cytoplasm GTP-binding Ligase Magnesium Membrane Metal-binding Nucleotide-binding Purine biosynthesis Reference proteome | MSGTRASNDR | MSGTRASNDRPPGTGGVKRGRLQQEAAATGSRVTVVLGAQWGDEGKGKVVDLLATDADIVSRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEKNEKKGLKDWEKRLIISDRAHLVFDFHQAVDGLQEVQRQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLSDFDEFSARFKNLAHQHQSMFPTLEIDVEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPPKKVLVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGD... | de novo' AMP biosynthetic process AMP biosynthetic process AMP salvage aspartate metabolic process IMP metabolic process purine nucleotide metabolic process cytoplasm; membrane actin filament binding adenylosuccinate synthase activity GTP binding GTPase activity identical protein binding magnesium ion binding Mus muscu... |
one-carbon metabolic process positive regulation of calcium-mediated signaling | cytoplasm | carbonate dehydratase activity hydro-lyase activity zinc ion binding | Mus musculus | Direct protein sequencing Metal-binding Phosphoprotein Reference proteome Zinc | MADLSFIEDA | MADLSFIEDAVAFPEKEEDEEEEEEEGVEWGYEEGVEWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTNDGHTIQVILKSKSVLSGGPLPQGQEFELYEVRFHWGRENQRGSEHTVNFKAFPMELHLIHWNSTLFGSIDEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCFNPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQMQIEEFRRLRTHVKGAELVEGCDGILGDNFRPTQPLSDRVIRAAFQ | one-carbon metabolic process positive regulation of calcium-mediated signaling cytoplasm carbonate dehydratase activity hydro-lyase activity zinc ion binding Mus musculus Direct protein sequencing Metal-binding Phosphoprotein Reference proteome Zinc MADLSFIEDA MADLSFIEDAVAFPEKEEDEEEEEEEGVEWGYEEGVEWGLVFPDANGEYQSPINLNSRE... |
activation of meiosis involved in egg activation apoptotic signaling pathway calcium ion transport cell differentiation cell projection morphogenesis G1/S transition of mitotic cell cycle long-term synaptic potentiation nervous system development neuromuscular process controlling balance phosphorylation positive regula... | calcium- and calmodulin-dependent protein kinase complex; centrosome; cytoplasm; cytosol; dendrite; glutamatergic synapse; neuron projection; perikaryon; postsynaptic density; sarcoplasmic reticulum membrane; spindle midzone | ATP binding calcium-dependent protein serine/threonine kinase activity calmodulin binding calmodulin-dependent protein kinase activity identical protein binding phospholipase binding protein homodimerization activity protein kinase binding protein serine kinase activity protein serine/threonine kinase activity structur... | Mus musculus | ATP-binding Calmodulin-binding Cytoplasm Cytoskeleton Differentiation Direct protein sequencing Kinase Membrane Neurogenesis Nucleotide-binding Phosphoprotein Reference proteome Sarcoplasmic reticulum Serine/threonine-protein kinase Synapse Transferase | MATTVTCTRF | MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLATRNFSVGRQT... | activation of meiosis involved in egg activation apoptotic signaling pathway calcium ion transport cell differentiation cell projection morphogenesis G1/S transition of mitotic cell cycle long-term synaptic potentiation nervous system development neuromuscular process controlling balance phosphorylation positive regula... |
articular cartilage development bone development | cell surface; collagen-containing extracellular matrix; extracellular matrix; extracellular space; sarcolemma; transport vesicle | cytokine binding extracellular matrix binding glycosaminoglycan binding | Mus musculus | Disulfide bond Extracellular matrix Glycoprotein Leucine-rich repeat Proteoglycan Reference proteome Repeat Secreted Signal | MCPLWLLTLL | MCPLWLLTLLLALSQALPFEQKGFWDFTLDDGLLMMNDEEASGSDTTSGVPDLDSVTPTFSAMCPFGCHCHLRVVQCSDLGLKTVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLSRVPAGLPDLKLLQVVYLHSNNITKVGIND... | articular cartilage development bone development cell surface; collagen-containing extracellular matrix; extracellular matrix; extracellular space; sarcolemma; transport vesicle cytokine binding extracellular matrix binding glycosaminoglycan binding Mus musculus Disulfide bond Extracellular matrix Glycoprotein Leucine-... |
negative regulation of angiogenesis negative regulation of endothelial cell migration negative regulation of vascular endothelial growth factor signaling pathway positive regulation of autophagy positive regulation of macroautophagy positive regulation of mitochondrial depolarization positive regulation of mitochondria... | collagen type VI trimer; collagen-containing extracellular matrix; extracellular space | collagen binding extracellular matrix binding glycosaminoglycan binding | Mus musculus | Disulfide bond Extracellular matrix Glycoprotein Leucine-rich repeat Proteoglycan Reference proteome Repeat Secreted Signal | MKATLIFFLL | MKATLIFFLLAQVSWAGPFEQRGLFDFMLEDEASGIIPYDPDNPLISMCPYRCQCHLRVVQCSDLGLDKVPWDFPPDTTLLDLQNNKITEIKEGAFKNLKDLHTLILVNNKISKISPEAFKPLVKLERLYLSKNQLKELPEKMPRTLQELRVHENEITKLRKSDFNGLNNVLVIELGGNPLKNSGIENGAFQGLKSLSYIRISDTNITAIPQGLPTSLTEVHLDGNKITKVDAPSLKGLINLSKLGLSFNSITVMENGSLANVPHLRELHLDNNKLLRVPAGLAQHKYIQVVYLHNNNISAVGQNDFCRAGHPSRKASYS... | negative regulation of angiogenesis negative regulation of endothelial cell migration negative regulation of vascular endothelial growth factor signaling pathway positive regulation of autophagy positive regulation of macroautophagy positive regulation of mitochondrial depolarization positive regulation of mitochondria... |
nervous system development nucleosome assembly positive regulation of neural precursor cell proliferation positive regulation of neurogenesis | chromatin; cytoplasm; melanosome; nucleus | chromatin binding histone binding histone chaperone activity kinase binding | Mus musculus | Acetylation Cytoplasm Direct protein sequencing Isopeptide bond Lipoprotein Methylation Neurogenesis Nucleus Phosphoprotein Prenylation Reference proteome | MADIDNKEQS | MADIDNKEQSELDQDLEDVEEVEEEETGEETKIKARQLTVQMMQNPQILAALQERLDGLVDTPTGYIESLPKVVKRRVNALKNLQVKCAQIEAKFYEEVHDLERKYAVLYQPLFDKRFEIINAIYEPTEEECEWKPDEEDEVSEELKEKAKIEDEKKDEEKEDPKGIPEFWLTVFKNVDLLSDMVQEHDEPILKHLKDIKVKFSDAGQPMSFVLEFHFEPNDYFTNEVLTKTYRMRSEPDDSDPFSFDGPEIMGCTGCQIDWKKGKNVTLKTIKKKQKHKGRGTVRTVTKTVSNDSFFNFFAPPEVPENGDLDDDAEAIL... | nervous system development nucleosome assembly positive regulation of neural precursor cell proliferation positive regulation of neurogenesis chromatin; cytoplasm; melanosome; nucleus chromatin binding histone binding histone chaperone activity kinase binding Mus musculus Acetylation Cytoplasm Direct protein sequencing... |
cerebral cortex development mRNA destabilization mRNA splice site recognition negative regulation of cell population proliferation negative regulation of epithelial cell proliferation negative regulation of gene expression positive regulation of gene expression positive regulation of multicellular organism growth post-... | cytoplasm; cytoplasmic stress granule; male germ cell nucleus; nucleoplasm; nucleus; perinucleolar compartment; ribonucleoprotein complex | BRE binding lncRNA binding mRNA 3'-UTR binding mRNA binding pre-mRNA binding RNA binding translation initiation factor binding | Mus musculus | Acetylation Activator Alternative splicing Cytoplasm Isopeptide bond mRNA processing mRNA splicing Nucleus Phosphoprotein Reference proteome Repeat RNA-binding Ubl conjugation | MNGTLDHPDQ | MNGTLDHPDQPDLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINILRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRTMAQTAIKAMHQAQTMEGCSSPMVVKFADTQKDKEQKRMAQQLQQQMQQISAASVWGNLAGLNTLGPQYLALYLQLLQQTASSGNLNTLSSLHPMGGLNAMQLQNLAALAAAASAAQNTPSGTNALTTSSSPLSVLTSSGSSPSSSSSNSVNPIASLGALQT... | cerebral cortex development mRNA destabilization mRNA splice site recognition negative regulation of cell population proliferation negative regulation of epithelial cell proliferation negative regulation of gene expression positive regulation of gene expression positive regulation of multicellular organism growth post-... |
brain development cytoskeleton-dependent cytokinesis flagellated sperm motility hematopoietic stem cell homeostasis negative regulation of stem cell proliferation neuron migration positive regulation of apoptotic process positive regulation of intrinsic apoptotic signaling pathway positive regulation of protein ubiquit... | axon; axon terminus; cell division site; cell projection; cytoplasm; cytosol; dendrite; microtubule cytoskeleton; mitochondrion; motile cilium; myelin sheath; nucleoplasm; perikaryon; septin complex; septin ring; sperm annulus; sperm flagellum; synaptic vesicle | GTP binding GTPase activity identical protein binding magnesium ion binding molecular adaptor activity | Mus musculus | Alternative splicing Cell cycle Cell division Cell projection Cilium Coiled coil Cytoplasm Cytoplasmic vesicle Differentiation Direct protein sequencing Flagellum GTP-binding Mitochondrion Nucleotide-binding Phosphoprotein Reference proteome Spermatogenesis Synapse Ubl conjugation | MDHSLGWQGN | MDHSLGWQGNSVPEDGTEAGIKHFLEDSSDDAELSKFVKDFPGSEPYHSAESKTRVARPQILEPRPQSPDLCDDDVEFRGSLWPQPSDSQQYFSAPAPLSPSSRPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDRKKCKIREEIEHFGIKIYQF... | brain development cytoskeleton-dependent cytokinesis flagellated sperm motility hematopoietic stem cell homeostasis negative regulation of stem cell proliferation neuron migration positive regulation of apoptotic process positive regulation of intrinsic apoptotic signaling pathway positive regulation of protein ubiquit... |
intracellular protein transport protein-containing complex disassembly regulation of receptor internalization regulation of synaptic vesicle priming SNARE complex disassembly synaptic transmission, glutamatergic synaptic vesicle endocytosis | glutamatergic synapse; myelin sheath; postsynapse; presynapse; presynaptic active zone membrane; synaptobrevin 2-SNAP-25-syntaxin-1a complex | SNARE binding soluble NSF attachment protein activity syntaxin binding | Mus musculus | Direct protein sequencing ER-Golgi transport Membrane Protein transport Reference proteome Transport | MDNAGKEREA | MDNAGKEREAVQLMAEAEKRVKASHSFLRGLFGGNTRIEEACEMYTRAANMFKMAKNWSAAGNAFCQAAKLHMQLQSKHDSATSFVDAGNAYKKADPQEAINCLNAAIDIYTDMGRFTIAAKHHITIAEIYETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKVAAYAAQLEQYQKAIEIYEQVGANTMDNPLLKYSAKDYFFKAALCHFIVDELNAKLALEKYEEMFPAFTDSRECKLLKKLLEAHEEQNSEAYTEAVKEFDSISRLDQWLTTMLLRIKKSIQGDGEGDGDLK | intracellular protein transport protein-containing complex disassembly regulation of receptor internalization regulation of synaptic vesicle priming SNARE complex disassembly synaptic transmission, glutamatergic synaptic vesicle endocytosis glutamatergic synapse; myelin sheath; postsynapse; presynapse; presynaptic acti... |
actin filament organization cell population proliferation central nervous system development positive regulation of cell population proliferation regulation of presynaptic cytosolic calcium ion concentration | cytoplasm; cytoskeleton; plasma membrane; presynaptic cytosol; presynaptic membrane; synaptic vesicle | actin filament binding calmodulin binding | Mus musculus | Actin-binding Calmodulin-binding Cell membrane Cytoplasm Cytoskeleton Lipoprotein Membrane Myristate Phosphoprotein Reference proteome | MGSQSSKAPR | MGSQSSKAPRGDVTAEEAAGASPAKANGQENGHVRSNGDLTPKGEGESPPVNGTDEAAGATGDAIEPAPPSQEAEAKGEVAPKETPKKKKKFSFKKPFKLSGLSFKRNRKEGGGDSSASSPTEEEQEQGEMSACSDEGTAQEGKAAATPESQEPQAKGAEASAASKEGDTEEEAGPQAAEPSTPSGPESGPTPASAEQNE | actin filament organization cell population proliferation central nervous system development positive regulation of cell population proliferation regulation of presynaptic cytosolic calcium ion concentration cytoplasm; cytoskeleton; plasma membrane; presynaptic cytosol; presynaptic membrane; synaptic vesicle actin fila... |
membrane fusion | azurophil granule lumen; cytoplasm; cytosol; extracellular exosome; extracellular region; plasma membrane | calcium ion binding protein heterodimerization activity protein homodimerization activity | Homo sapiens | 3D-structure Calcium Cytoplasm Direct protein sequencing Membrane Metal-binding Reference proteome Repeat | MAYPGYGGGF | MAYPGYGGGFGNFSIQVPGMQMGQPVPETGPAILLDGYSGPAYSDTYSSAGDSVYTYFSAVAGQDGEVDAEELQRCLTQSGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAALNAWKENFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKRYSKNGRIFFDDYVACCVKLRALTDFFRKRDHLQQGSANFIYDDFLQGTMAI | membrane fusion azurophil granule lumen; cytoplasm; cytosol; extracellular exosome; extracellular region; plasma membrane calcium ion binding protein heterodimerization activity protein homodimerization activity Homo sapiens 3D-structure Calcium Cytoplasm Direct protein sequencing Membrane Metal-binding Reference prote... |
angiogenesis axon guidance axonal fasciculation dendritic spine development dendritic spine morphogenesis ephrin receptor signaling pathway peptidyl-tyrosine phosphorylation positive regulation of synapse assembly spinothalamic tract morphogenesis | axon; dendrite; plasma membrane | ATP binding protein tyrosine kinase activity transmembrane-ephrin receptor activity | Gallus gallus | 3D-structure Alternative splicing ATP-binding Cell membrane Cell projection Developmental protein Disulfide bond Glycoprotein Kinase Membrane Neurogenesis Nucleotide-binding Receptor Reference proteome Repeat Signal Transferase Transmembrane Transmembrane helix Tyrosine-protein kinase | MGPLWFCCLP | MGPLWFCCLPLALLPLLAAVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVFESSQNNWLRTKYIRRRGAHRIHVEMKFSVRDCSSIPNVPGSCKETFNLYYYESDFDSATKTFPNWMENPWMKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSKNGFYLAFQDYGGCMSLIAVRVFYRKCPRVIQNGAVFQETLSGAESTSLVAARGTCISNAEEVDVPIKLYCNGDGEWLVPIGRCMCRPGYESVENGTVCRGCPSGTFKASQGDEGCVHCPINSRTTSEGATNCVCRNGYYRADADPVDM... | angiogenesis axon guidance axonal fasciculation dendritic spine development dendritic spine morphogenesis ephrin receptor signaling pathway peptidyl-tyrosine phosphorylation positive regulation of synapse assembly spinothalamic tract morphogenesis axon; dendrite; plasma membrane ATP binding protein tyrosine kinase acti... |
negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription | nucleoplasm | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific metal ion binding protein homodimerization activity RNA polyme... | Homo sapiens | 3D-structure Alternative splicing DNA-binding Isopeptide bond Metal-binding Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | MRPAVLGSPD | MRPAVLGSPDRAPPEDEGPVMVKLEDSEEEGEAALWDPGPEAARLRFRCFRYEEATGPQEALAQLRELCRQWLRPEVRSKEQMLELLVLEQFLGALPPEIQARVQGQRPGSPEEAAALVDGLRREPGGPRRWVTVQVQGQEVLSEKMEPSSFQPLPETEPPTPEPGPKTPPRTMQESPLGLQVKEESEVTEDSDFLESGPLAATQESVPTLLPEEAQRCGTVLDQIFPHSKTGPEGPSWREHPRALWHEEAGGIFSPGFALQLGSISAGPGSVSPHLHVPWDLGMAGLSGQIQSPSREGGFAHALLLPSDLRSEQDPTDE... | negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription nucleoplasm DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor ac... |
anatomical structure development cell differentiation positive regulation of transcription by RNA polymerase II response to retinoic acid retinoic acid receptor signaling pathway | RNA polymerase II transcription regulator complex; transcription regulator complex | cis-regulatory region sequence-specific DNA binding nuclear receptor activity nuclear steroid receptor activity retinoic acid-responsive element binding zinc ion binding | Gallus gallus | Alternative splicing DNA-binding Metal-binding Nucleus Receptor Reference proteome Transcription Transcription regulation Zinc Zinc-finger | MYGNYPHFIK | MYGNYPHFIKFPAGFGNSPVHASSTSVSPSSSLSVGSTVDGHHNYLEAPTNASRALPSPMNTIGSPVNALGSPYRVIASSIGSHPVALSSSAPGMNFVTHSPQPNVLNNVSSSEDIKPLPGLPGIGNMNYPSTSPGSLAKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQGSRERSENEAESTSGGSEDMPVERILEAELAVEPKTEAYSDVNTESSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSH... | anatomical structure development cell differentiation positive regulation of transcription by RNA polymerase II response to retinoic acid retinoic acid receptor signaling pathway RNA polymerase II transcription regulator complex; transcription regulator complex cis-regulatory region sequence-specific DNA binding nuclea... |
anatomical structure development cell differentiation hormone-mediated signaling pathway mRNA transcription by RNA polymerase II positive regulation of bone mineralization positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of vitamin D recept... | chromatin; cytosol; nucleolus; nucleoplasm; nucleus; RNA polymerase II transcription regulator complex | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific nuclear receptor activity nuclear steroid receptor activity retinoic acid-responsive element binding RNA polymerase II transcription regulatory region sequence-specific DNA bind... | Homo sapiens | 3D-structure Alternative splicing Cytoplasm DNA-binding Metal-binding Methylation Nucleus Receptor Reference proteome Transcription Transcription regulation Zinc Zinc-finger | MSWAARPPFL | MSWAARPPFLPQRHAAGQCGPVGVRKEMHCGVASRWRRRRPWLDPAAAAAAAVAGGEQQTPEPEPGEAGRDGMGDSGRDSRSPDSSSPNPLPQGVPPPSPPGPPLPPSTAPSLGGSGAPPPPPMPPPPLGSPFPVISSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVKPPVLGVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGEGAGGAPEEMPVDRILEAELAVEQKSDQGVE... | anatomical structure development cell differentiation hormone-mediated signaling pathway mRNA transcription by RNA polymerase II positive regulation of bone mineralization positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of vitamin D recept... |
anatomical structure development cardiac muscle cell proliferation cell differentiation cellular response to retinoic acid hormone-mediated signaling pathway in utero embryonic development maternal placenta development mRNA transcription by RNA polymerase II positive regulation of bone mineralization positive regulatio... | cytosol; nucleolus; nucleoplasm; nucleus; RNA polymerase II transcription regulator complex | chromatin DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific nuclear receptor activity nuclear receptor coactivator activity nuclear retinoic acid receptor binding nuclear steroid receptor activity nuclear thyroid hormone receptor binding nuclear vitamin D receptor binding protein-cont... | Mus musculus | Alternative splicing Cytoplasm DNA-binding Metal-binding Methylation Nucleus Receptor Reference proteome Transcription Transcription regulation Zinc Zinc-finger | MSWATRPPFL | MSWATRPPFLPPRHAAGQCGPVGVRKEMHCGVASRWRRRRPWLDPAAAAAAAGEQQALEPEPGEAGRDGMGDSGRDSRSPDSSSPNPLSQGIRPSSPPGPPLTPSAPPPPMPPPPLGSPFPVISSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVKPPVLGVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGDGAGGAPEEMPVDRILEAELAVEQKSDQGVEGPGATGGGGSSPN... | anatomical structure development cardiac muscle cell proliferation cell differentiation cellular response to retinoic acid hormone-mediated signaling pathway in utero embryonic development maternal placenta development mRNA transcription by RNA polymerase II positive regulation of bone mineralization positive regulatio... |
anatomical structure development cell differentiation positive regulation of transcription by RNA polymerase II regulation of myelination response to retinoic acid retinoic acid receptor signaling pathway | cytoplasm; RNA polymerase II transcription regulator complex | molecular condensate scaffold activity nuclear receptor activity nuclear steroid receptor activity retinoic acid-responsive element binding sequence-specific DNA binding sequence-specific double-stranded DNA binding zinc ion binding | Mus musculus | Cytoplasm DNA-binding Metal-binding Nucleus Receptor Reference proteome Transcription Transcription regulation Zinc Zinc-finger | MYGNYSHFMK | MYGNYSHFMKFPTGFGGSPGHTGSTSMSPSVALPTGKPMDSHPSYTDTPVSAPRTLSAVGTPLNALGSPYRVITSAMGPPSGALAAPPGINLVAPPSSQLNVVNSVSSSEDIKPLPGLPGIGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECASSSHEDMPVERILEAELAVEPKTESYGDMNVENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVS... | anatomical structure development cell differentiation positive regulation of transcription by RNA polymerase II regulation of myelination response to retinoic acid retinoic acid receptor signaling pathway cytoplasm; RNA polymerase II transcription regulator complex molecular condensate scaffold activity nuclear recepto... |
chaperone-mediated protein complex assembly negative regulation of DNA binding positive regulation of telomere maintenance via telomerase protein folding | cytoplasm; cytosol; nucleus | Hsp90 protein binding protein-folding chaperone binding | Saccharomyces cerevisiae | 3D-structure Acetylation Chaperone Reference proteome Repeat | MSDKVINPQV | MSDKVINPQVAWAQRSSTTDPERNYVLITVSIADCDAPELTIKPSYIELKAQSKPHVGDENVHHYQLHIDLYKEIIPEKTMHKVANGQHYFLKLYKKDLESEYWPRLTKEKVKYPYIKTDFDKWVDEDEQDEVEAEGNDAAQGMDFSQMMGGAGGAGGAGGMDFSQMMGGAGGAGSPDMAQLQQLLAQSGGNLDMGDFKENDEEDEEEEIEPEVKA | chaperone-mediated protein complex assembly negative regulation of DNA binding positive regulation of telomere maintenance via telomerase protein folding cytoplasm; cytosol; nucleus Hsp90 protein binding protein-folding chaperone binding Saccharomyces cerevisiae 3D-structure Acetylation Chaperone Reference proteome Re... |
intracellular signal transduction negative regulation of conjugation with cellular fusion negative regulation of transcription by RNA polymerase II phosphorylation response to pheromone | cell cortex; cytoplasm | ATP binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity | Saccharomyces cerevisiae | Acetylation ATP-binding Cytoplasm Kinase Nucleotide-binding Pheromone response Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MDEYSSIYSQ | MDEYSSIYSQPKTPRLKQEGFPDSIGDQHEKALIDENGEEDKKMASTEGTTGDSRSTPLTVSIPTFENVQALPTPMTYTPLSPGNLSMSPIDQSSLNIPKRRSHARLLDDMLSVTQPNQRVVSELIAPANLSPQRVVSLPTVTEEALVNDSVDSDNYTKEPYFPESSSSTEKCDDDIFQGFLLDHWDRPLLWKKVRPIGSGNFSTVLLYELMDQSNPKLKQVAVKRLKYPEELSNVEQINTSLRYKETLSRLENSLTRELQVLKSLNHPCIVKLLGINNPIFVTSKKPLCDLIIKTPRALPPCDMIMSYCPAGDLLAAVM... | intracellular signal transduction negative regulation of conjugation with cellular fusion negative regulation of transcription by RNA polymerase II phosphorylation response to pheromone cell cortex; cytoplasm ATP binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity Sac... |
extraction of mislocalized protein from mitochondrial outer membrane protein hexamerization protein targeting to mitochondrion | mitochondrial outer membrane; mitochondrion; peroxisomal membrane | ATP binding ATP hydrolysis activity membrane protein dislocase activity | Saccharomyces cerevisiae | 3D-structure ATP-binding Membrane Mitochondrion Mitochondrion outer membrane Nucleotide-binding Peroxisome Reference proteome Translocase Transmembrane Transmembrane helix | MSRKFDLKTI | MSRKFDLKTITDLSVLVGTGISLYYLVSRLLNDVESGPLSGKSRESKAKQSLQWEKLVKRSPALAEVTLDAYERTILSSIVTPDEINITFQDIGGLDPLISDLHESVIYPLMMPEVYSNSPLLQAPSGVLLYGPPGCGKTMLAKALAKESGANFISIRMSSIMDKWYGESNKIVDAMFSLANKLQPCIIFIDEIDSFLRERSSTDHEVTATLKAEFMTLWDGLLNNGRVMIIGATNRINDIDDAFLRRLPKRFLVSLPGSDQRYKILSVLLKDTKLDEDEFDLQLIADNTKGFSGSDLKELCREAALDAAKEYIKQKRQL... | extraction of mislocalized protein from mitochondrial outer membrane protein hexamerization protein targeting to mitochondrion mitochondrial outer membrane; mitochondrion; peroxisomal membrane ATP binding ATP hydrolysis activity membrane protein dislocase activity Saccharomyces cerevisiae 3D-structure ATP-binding Memb... |
anterograde axonal protein transport anterograde dendritic transport of messenger ribonucleoprotein complex anterograde dendritic transport of neurotransmitter receptor complex axon guidance intracellular mRNA localization motor neuron axon guidance mRNA transport synaptic vesicle transport | axon cytoplasm; axonal growth cone; ciliary rootlet; cytoplasm; dendrite; dendrite cytoplasm; distal axon; kinesin complex; microtubule; neuron projection; neuronal cell body; postsynaptic cytosol | apolipoprotein receptor binding ATP binding ATP hydrolysis activity microtubule binding microtubule motor activity plus-end-directed microtubule motor activity | Mus musculus | 3D-structure ATP-binding Cell projection Coiled coil Cytoplasm Cytoskeleton Direct protein sequencing Hydrolase Microtubule Motor protein Nucleotide-binding Phosphoprotein Reference proteome Transport | MADPAECSIK | MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMF... | anterograde axonal protein transport anterograde dendritic transport of messenger ribonucleoprotein complex anterograde dendritic transport of neurotransmitter receptor complex axon guidance intracellular mRNA localization motor neuron axon guidance mRNA transport synaptic vesicle transport axon cytoplasm; axonal growt... |
cytoplasmic microtubule organization establishment or maintenance of microtubule cytoskeleton polarity karyogamy involved in conjugation with cellular fusion meiotic centromere clustering meiotic spindle formation (spindle phase two) microtubule anchoring at mitotic spindle pole body microtubule bundle formation microt... | astral microtubule; cortical microtubule; kinesin complex; kinetochore; meiotic spindle pole; microtubule; microtubule minus-end; microtubule organizing center; microtubule plus-end; minus-end kinesin complex; mitotic spindle; mitotic spindle polar microtubule; nucleus | ATP binding ATP hydrolysis activity microtubule binding microtubule motor activity minus-end-directed microtubule motor activity | Emericella nidulans | ATP-binding Coiled coil Cytoplasm Cytoskeleton Microtubule Motor protein Nucleotide-binding Reference proteome | MENVQSRMQG | MENVQSRMQGSRIPGLKEMNPSGTNARSRLPQPGAIANKPTAVPQLARTRSTTESTRIGAGPPSAARSVNGATKAHTRANSYANSSTLTRSASAASRPRGPLSSSTSGRPKTSMSTSRRPNGHALPRPATSLDTHQEERSYGGLGKRGEWDQDEREQNLESLFETFVSRISQQGQESSGLKDALEVYKSRVGELEEAKSEQTEQNIRLKVELDVSKSRLAEAEDALKNAQRDHEIAIDELMSRQRAECESVRYESQKSLDALKAQHESELKELRRQFERELEDEKCARVRELNQLHSKTALDAQLSQIELDKTIKELAAT... | cytoplasmic microtubule organization establishment or maintenance of microtubule cytoskeleton polarity karyogamy involved in conjugation with cellular fusion meiotic centromere clustering meiotic spindle formation (spindle phase two) microtubule anchoring at mitotic spindle pole body microtubule bundle formation microt... |
cell differentiation cell division microtubule cytoskeleton organization microtubule-based movement mitotic spindle assembly mitotic spindle organization nervous system development regulation of cell migration | centriolar subdistal appendage; centriole; centrosome; cytoplasm; kinesin complex; lysosome; microtubule; nuclear body; nucleolus; nucleoplasm; sperm principal piece; spindle; spindle pole | ATP binding ATP hydrolysis activity microtubule binding microtubule motor activity protein kinase binding | Mus musculus | Acetylation Alternative splicing ATP-binding Cell cycle Cell division Coiled coil Cytoplasm Cytoskeleton Developmental protein Differentiation Lysosome Microtubule Mitosis Motor protein Neurogenesis Nucleotide-binding Phosphoprotein Reference proteome | MATANFGKIQ | MATANFGKIQIGIYVEIKRSDGRIHQAMVTSLNEDNESVTVEWIENGDTKGKEIDLESIFSLNPDLVPDEDIEPSPELPPPSSSSKVNKIVKNRRTVAAVKNDPPPRDNRVVGSARARPSQLPEQSSSAQQNGSVSDISPVQAAKKEFGPPSRRKSNCVKEVEKLQEKREKRRLQQQELREKRAQDVDATNPNYEIMCMIRDFRGSLDYRPLTTADPIDEHRICVCVRKRPLNKKETQMKDLDVITIPSKDVVMVHEPKQKVDLTRYLENQTFRFDYAFDDSAPNEMVYRFTARPLVETIFERGMATCFAYGQTGSGKTH... | cell differentiation cell division microtubule cytoskeleton organization microtubule-based movement mitotic spindle assembly mitotic spindle organization nervous system development regulation of cell migration centriolar subdistal appendage; centriole; centrosome; cytoplasm; kinesin complex; lysosome; microtubule; nucl... |
cell cycle cell division microtubule-based movement negative regulation of microtubule depolymerization nuclear migration along microtubule | cortical microtubule plus-end; cytoplasmic microtubule; kinesin complex; microtubule; mitochondrion; spindle pole body | ATP binding ATP hydrolysis activity microtubule binding microtubule motor activity plus-end-directed microtubule motor activity | Saccharomyces cerevisiae | ATP-binding Cell cycle Cell division Coiled coil Cytoplasm Cytoskeleton Microtubule Mitosis Motor protein Nucleotide-binding Reference proteome | MIQKMSPSLR | MIQKMSPSLRRPSTRSSSGSSNIPQSPSVRSTSSFSNLTRNSIRSTSNSGSQSISASSTRSNSPLRSVSAKSDPFLHPGRIRIRRSDSINNNSRKNDTYTGSITVTIRPKPRSVGTSRDHVGLKSPRYSQPRSNSHHGSNTFVRDPWFITNDKTIVHEEIGEFKFDHVFASHCTNLEVYERTSKPMIDKLLMGFNATIFAYGMTGSGKTFTMSGNEQELGLIPLSVSYLFTNIMEQSMNGDKKFDVIISYLEIYNERIYDLLESGLEESGSRISTPSRLYMSKSNSNGLGVELKIRDDSQYGVKVIGLTERRCESSEELL... | cell cycle cell division microtubule-based movement negative regulation of microtubule depolymerization nuclear migration along microtubule cortical microtubule plus-end; cytoplasmic microtubule; kinesin complex; microtubule; mitochondrion; spindle pole body ATP binding ATP hydrolysis activity microtubule binding micro... |
cell division mitotic nuclear membrane organization positive regulation of protein export from nucleus Ran protein signal transduction regulation of exit from mitosis regulation of mitotic spindle assembly regulation of mitotic spindle elongation | chromatin; cytoplasm; mitotic spindle midzone; nucleus | guanyl-nucleotide exchange factor activity | Schizosaccharomyces pombe | Cell cycle Cell division Guanine-nucleotide releasing factor Mitosis Nucleus Reference proteome Repeat | MTSNRSTRSS | MTSNRSTRSSTKREEVSKNGVEKRELDESDVMKNGKKPVKRAKVSSLPKPVRVPGSAKRINKIPELPTERLNVYVFGSGSMNELGMGEEEMDVVYRPRLNPILSTDKVGVVDLAVGGMHSAALSHDGRVYTWGVNDDYALGRLTKDQKDENGDKVDNDLLEGTPSKVEGALSHLRVTKVICSDNLTAAITDNGCCFTWGTFRCSDGVLGYSDSQKRTAEPTQMRLPEICQLATGTDHIIALTTTGKVYTWGNGQQFQLGRRMLERRRLQGLTPQPLALKNIISVGAGSYHSFAIDNKGRVYAWGLNITRQCGIEVEDEEE... | cell division mitotic nuclear membrane organization positive regulation of protein export from nucleus Ran protein signal transduction regulation of exit from mitosis regulation of mitotic spindle assembly regulation of mitotic spindle elongation chromatin; cytoplasm; mitotic spindle midzone; nucleus guanyl-nucleotide ... |
anterior/posterior axis specification, embryo bicoid mRNA localization embryonic development via the syncytial blastoderm mRNA splicing, via spliceosome ovarian nurse cell to oocyte transport pole plasm oskar mRNA localization regulation of pole plasm oskar mRNA localization spermatogenesis | cytoplasm; cytoplasmic ribonucleoprotein granule; P-body; precatalytic spliceosome | protein homodimerization activity single-stranded RNA binding | Drosophila melanogaster | 3D-structure Cytoplasm Developmental protein Phosphoprotein Reference proteome RNA-binding | MVADNIDAGV | MVADNIDAGVAIAVADQSSSPVGDKVELPAGNYILVGVDIDTTGRRLMDEIVQLAAYTPTDHFEQYIMPYMNLNPAARQRHQVRVISIGFYRMLKSMQTYKIIKSKSEIAALKDFLNWLEQLKTKAGPSSDGIVLIYHEERKFIPYMILESLKKYGLLERFTASVKSFANSINLAKASIGDANIKNYSLRKLSKILSTTKEEDAACSASTSGSGSGLGSGSSMVSDSVSISPRDSTVTNGDDKQSSKNAVQGKRELFDGNASVRAKLAFDVALQLSNSDGKPEPKSSEALENMFNAIRPFAKLVVSDVLELDIQIENLER... | anterior/posterior axis specification, embryo bicoid mRNA localization embryonic development via the syncytial blastoderm mRNA splicing, via spliceosome ovarian nurse cell to oocyte transport pole plasm oskar mRNA localization regulation of pole plasm oskar mRNA localization spermatogenesis cytoplasm; cytoplasmic ribon... |
cell population proliferation cellular response to granulocyte macrophage colony-stimulating factor stimulus embryonic placenta development granulocyte-macrophage colony-stimulating factor signaling pathway immune response macrophage differentiation monocyte differentiation myeloid dendritic cell differentiation negati... | extracellular space; granulocyte macrophage colony-stimulating factor receptor complex; intracellular membrane-bounded organelle | cytokine activity granulocyte macrophage colony-stimulating factor receptor binding growth factor activity | Ovis aries | 3D-structure Cytokine Disulfide bond Glycoprotein Growth factor Reference proteome Secreted Signal | MWLQNLLLLG | MWLQNLLLLGTVVCSFSAPTRQPSPVTRPWQHVDAIKEALSLLNDSTDTAAVMDETVEVVSEMFDSQEPTCLQTRLELYKQGLRGSLTSLTGSLTMMASHYKKHCPPTQETSCETQIITFKSFKENLKDFLFIIPFDCWEPVQK | cell population proliferation cellular response to granulocyte macrophage colony-stimulating factor stimulus embryonic placenta development granulocyte-macrophage colony-stimulating factor signaling pathway immune response macrophage differentiation monocyte differentiation myeloid dendritic cell differentiation negati... |
de novo' NAD biosynthetic process from tryptophan defense response inflammatory response kynurenic acid biosynthetic process multicellular organismal response to stress negative regulation of activated T cell proliferation negative regulation of interleukin-10 production negative regulation of T cell apoptotic process ... | cytoplasm; cytosol; smooth muscle contractile fiber; stereocilium bundle | amino acid binding heme binding indoleamine 2,3-dioxygenase activity metal ion binding oxygen binding tryptophan 2,3-dioxygenase activity | Mus musculus | Cytoplasm Dioxygenase Direct protein sequencing Heme Immunity Iron Metal-binding Oxidoreductase Reference proteome Tryptophan catabolism | MALSKISPTE | MALSKISPTEGSRRILEDHHIDEDVGFALPHPLVELPDAYSPWVLVARNLPVLIENGQLREEVEKLPTLSTDGLRGHRLQRLAHLALGYITMAYVWNRGDDDVRKVLPRNIAVPYCELSEKLGLPPILSYADCVLANWKKKDPNGPMTYENMDILFSFPGGDCDKGFFLVSLLVEIAASPAIKAIPTVSSAVERQDLKALEKALHDIATSLEKAKEIFKRMRDFVDPDTFFHVLRIYLSGWKCSSKLPEGLLYEGVWDTPKMFSGGSAGQSSIFQSLDVLLGIKHEAGKESPAEFLQEMREYMPPAHRNFLFFLESAPPV... | de novo' NAD biosynthetic process from tryptophan defense response inflammatory response kynurenic acid biosynthetic process multicellular organismal response to stress negative regulation of activated T cell proliferation negative regulation of interleukin-10 production negative regulation of T cell apoptotic process ... |
amino acid biosynthetic process aromatic amino acid family biosynthetic process chorismate biosynthetic process | cytoplasm; cytosol | chorismate synthase activity FMN binding FMN reductase (NAD(P)H) activity FMN reductase (NADPH) activity riboflavin reductase (NADPH) activity | Saccharomyces cerevisiae | 3D-structure Acetylation Amino-acid biosynthesis Aromatic amino acid biosynthesis Flavoprotein FMN Lyase Oxidoreductase Reference proteome Stress response | MSTFGKLFRV | MSTFGKLFRVTTYGESHCKSVGCIVDGVPPGMSLTEADIQPQLTRRRPGQSKLSTPRDEKDRVEIQSGTEFGKTLGTPIAMMIKNEDQRPHDYSDMDKFPRPSHADFTYSEKYGIKASSGGGRASARETIGRVASGAIAEKFLAQNSNVEIVAFVTQIGEIKMNRDSFDPEFQHLLNTITREKVDSMGPIRCPDASVAGLMVKEIEKYRGNKDSIGGVVTCVVRNLPTGLGEPCFDKLEAMLAHAMLSIPASKGFEIGSGFQGVSVPGSKHNDPFYFEKETNRLRTKTNNSGGVQGGISNGENIYFSVPFKSVATISQEQ... | amino acid biosynthetic process aromatic amino acid family biosynthetic process chorismate biosynthetic process cytoplasm; cytosol chorismate synthase activity FMN binding FMN reductase (NAD(P)H) activity FMN reductase (NADPH) activity riboflavin reductase (NADPH) activity Saccharomyces cerevisiae 3D-structure Acetyla... |
activation of cysteine-type endopeptidase activity involved in apoptotic process antimicrobial humoral immune response mediated by antimicrobial peptide apoptotic process astrocyte development autocrine signaling autophagy chronic inflammatory response endothelial cell migration innate immune response leukocyte migrati... | cytoplasm; cytoskeleton; extracellular region; plasma membrane | antioxidant activity calcium ion binding calcium-dependent protein binding | Bos taurus | Antimicrobial Antioxidant Apoptosis Autophagy Calcium Cell membrane Chemotaxis Cytoplasm Cytoskeleton Direct protein sequencing Immunity Inflammatory response Innate immunity Membrane Metal-binding Methylation Phosphoprotein Reference proteome Repeat Secreted Zinc | MEDKMSQMES | MEDKMSQMESSIETIINIFHQYSVRLGHYDTLIQKEFKQLVQKELPNFLKKQKKNEAAINEIMEDLDTNVDKQLSFEEFIMLVARLTVASHEEMHNTAPPGQGHRHGPGYGKGGSGSCSGQGSPDQGSHDLGSHGHGHGHSHGGHGHSHGGHGHSH | activation of cysteine-type endopeptidase activity involved in apoptotic process antimicrobial humoral immune response mediated by antimicrobial peptide apoptotic process astrocyte development autocrine signaling autophagy chronic inflammatory response endothelial cell migration innate immune response leukocyte migrati... |
protein transport retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum vesicle fusion with endoplasmic reticulum | cytoplasmic side of endoplasmic reticulum membrane; endoplasmic reticulum; Golgi to ER transport vesicle membrane; membrane; SNARE complex | SNAP receptor activity | Saccharomyces cerevisiae | 3D-structure Coiled coil Endoplasmic reticulum ER-Golgi transport Glycoprotein Membrane Protein transport Reference proteome Transmembrane Transmembrane helix Transport | MVVTFLQDLE | MVVTFLQDLEVLQDALLNNLQKLSAISRRKESGESKHDNKDSFAAIANEHNDEEEEIEFEDLVNIIESKVSDFESVLKCSIVEMTYKYPELKLQWEKSPRYDQCDKLHIVKLDKQMNEDIYAQLVEELDFVLQFVDWFYCYRLKVKEILRQHHKRDLAWNDEKRDRAIKFHAVDYDKLHQGTSSSSSLTSTSMEKASTREKLLSKTKQLTNNLVRGNQILQSGILQSDLNLDELRAQTNSLTQIDDKYTQFETVFKKTADLVKVLENASHQEKRDVYLSLGFLLCCVSWVLWRRIFKLPVKLGLWLLFKFFKGILVTLGL... | protein transport retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum vesicle fusion with endoplasmic reticulum cytoplasmic side of endoplasmic reticulum membrane; endoplasmic reticulum; Golgi to ER transport vesicle membrane; membrane; SNARE complex SNAP receptor activity Saccharomyces cerevisiae 3D... |
fatty acid beta-oxidation | fatty acid beta-oxidation multienzyme complex | 3-hydroxyacyl-CoA dehydrogenase activity 3-hydroxybutyryl-CoA epimerase activity delta(3)-delta(2)-enoyl-CoA isomerase activity enoyl-CoA hydratase activity NAD+ binding | Pseudomonas fragi | 3D-structure Direct protein sequencing Fatty acid metabolism Isomerase Lipid degradation Lipid metabolism Lyase Multifunctional enzyme NAD Oxidoreductase | MIYEGKAITV | MIYEGKAITVTALESGIVELKFDLKGESVNKFNRLTLNELRQAVDAIKADASVKGVIVSSGKDVFIVGADITEFVENFKLPDAELIAGNLEANKIFSDFEDLNVPTVAAINGIALGGGLEMCLAADFRVMADSAKIGLPEVKLGIYPGFGGTVRLPRLIGVDNAVEWIASGKENRAEDALKVSAVDAVVTADKLGAAALDLIKRAISGELDYKAKRQPKLEKLKLNAIEQMMAFETAKGFVAGQAGPNYPAPVEAIKTIQKAANFGRDKALEVEAAGFAKLAKTSASNCLIGLFLNDQELKKKAKVYDKIAKDVKQAAVL... | fatty acid beta-oxidation fatty acid beta-oxidation multienzyme complex 3-hydroxyacyl-CoA dehydrogenase activity 3-hydroxybutyryl-CoA epimerase activity delta(3)-delta(2)-enoyl-CoA isomerase activity enoyl-CoA hydratase activity NAD+ binding Pseudomonas fragi3D-structure Direct protein sequencing Fatty acid metabolism ... |
ER-dependent peroxisome organization peroxisome inheritance protein import into peroxisome membrane | endoplasmic reticulum; peroxisomal membrane; peroxisome | protein-macromolecule adaptor activity | Saccharomyces cerevisiae | Membrane Peroxisome Reference proteome Transmembrane Transmembrane helix | MAPNQRSRSL | MAPNQRSRSLLQRHRGKVLISLTGIAALFTTGSVVVFFVKRWLYKQQLRITEQHFIKEQIKRRFEQTQEDSLYTIYELLPVWRMVLNENDLNLDSIVTQLKDQKNQLTRAKSSESRESSPLKSKAELWNELELKSLIKLVTVTYTVSSLILLTRLQLNILTRNEYLDSAIKLTMQQENCNKLQNRFYNWVTSWWSDPEDKADDAMVMAAKKSKKEGQEVYINEQAFLSLSWWILNKGWLSYNEIITNQIEIEFDGIHPRDTLTLEEFSSRLTNIFRNTNSQIFQQNNNNLTSILLPKDSSGQEFLLSQTLDADALTSFHS... | ER-dependent peroxisome organization peroxisome inheritance protein import into peroxisome membrane endoplasmic reticulum; peroxisomal membrane; peroxisome protein-macromolecule adaptor activity Saccharomyces cerevisiae Membrane Peroxisome Reference proteome Transmembrane Transmembrane helix MAPNQRSRSL MAPNQRSRSLLQRHR... |
astrocyte activation involved in immune response lysosomal lumen acidification lysosomal transport lysosome organization microglial cell activation involved in immune response negative regulation of microglial cell activation negative regulation of neuron apoptotic process negative regulation of neutrophil activation n... | azurophil granule lumen; endoplasmic reticulum; endosome; extracellular exosome; extracellular region; extracellular space; Golgi apparatus; late endosome; lysosomal membrane; lysosome; membrane; plasma membrane; trans-Golgi network | cytokine activity growth factor activity protein-folding chaperone binding RNA binding | Homo sapiens | 3D-structure Alternative splicing Cytokine Direct protein sequencing Disulfide bond Glycoprotein Lysosome Neurodegeneration Neuronal ceroid lipofuscinosis Reference proteome Repeat Secreted Signal | MWTLVSWVAL | MWTLVSWVALTAGLVAGTRCPDGQFCPVACCLDPGGASYSCCRPLLDKWPTTLSRHLGGPCQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQRSGNNSVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCITPTGTHPLAKKLPAQRTNRAVALSSSVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSKENATTDLLTKLPAHTVGDVKCDMEVSCPDGYTCCRLQSGAWGCCPFTQAVCCEDHIH... | astrocyte activation involved in immune response lysosomal lumen acidification lysosomal transport lysosome organization microglial cell activation involved in immune response negative regulation of microglial cell activation negative regulation of neuron apoptotic process negative regulation of neutrophil activation n... |
acute-phase response negative regulation of fibrinolysis | extracellular space | serine-type endopeptidase inhibitor activity | Bos taurus | Acute phase Direct protein sequencing Disulfide bond Glycoprotein Protease inhibitor Reference proteome Secreted Serine protease inhibitor Signal Sulfation | MALLWGLLAL | MALLWGLLALILSCLSSLCSAQFSPVSTMEPLDLQLMDGQAQQKLPPLSLLKLDNQEPGGQIAPKKAPEDCKLSPTPEQTRRLARAMMTFTTDLFSLVAQSSTRPNLILSPLSVALALSHLALGAQNQTLQRLKEVLHADSGPCLPHLLSRLCQDLGPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPMSLTGMKGEDLANINRWVKEATEGKIEDFLSDLPDDTVLLLLNAIHFQGFWRSKFDPNLTQRGAFHLDEQFTVPVDMMQALTYPLHWFLLEQPEIQVAHFPFKNNMSFVVLMPTRFEWNASQVLANLTW... | acute-phase response negative regulation of fibrinolysis extracellular space serine-type endopeptidase inhibitor activity Bos taurus Acute phase Direct protein sequencing Disulfide bond Glycoprotein Protease inhibitor Reference proteome Secreted Serine protease inhibitor Signal Sulfation MALLWGLLAL MALLWGLLALILSCLSSLCS... |
mitochondrial translation valine catabolic process | mitochondrial inner membrane; mitochondrial small ribosomal subunit; mitochondrion | 3-hydroxyisobutyryl-CoA hydrolase activity structural constituent of ribosome | Saccharomyces cerevisiae | 3D-structure Branched-chain amino acid catabolism Hydrolase Mitochondrion Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein | MLRNTLKCAQ | MLRNTLKCAQLSSKYGFKTTTRTFMTTQPQLNVTDAPPVLFTVQDTARVITLNRPKKLNALNAEMSESMFKTLNEYAKSDTTNLVILKSSNRPRSFCAGGDVATVAIFNFNKEFAKSIKFFTDEYSLNFQIATYLKPIVTFMDGITMGGGVGLSIHTPFRIATENTKWAMPEMDIGFFPDVGSTFALPRIVTLANSNSQMALYLCLTGEVVTGADAYMLGLASHYVSSENLDALQKRLGEISPPFNNDPQSAYFFGMVNESIDEFVSPLPKDYVFKYSNEKLNVIEACFNLSKNGTIEDIMNNLRQYEGSAEGKAFAQEI... | mitochondrial translation valine catabolic process mitochondrial inner membrane; mitochondrial small ribosomal subunit; mitochondrion 3-hydroxyisobutyryl-CoA hydrolase activity structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Branched-chain amino acid catabolism Hydrolase Mitochondrion Phosphop... |
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