Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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protein folding ubiquitin-dependent ERAD pathway | endoplasmic reticulum; endoplasmic reticulum membrane; fungal-type vacuole; membrane | calcium ion binding carbohydrate binding unfolded protein binding | Schizosaccharomyces pombe | Calcium Chaperone Disulfide bond Endoplasmic reticulum Glycoprotein Lectin Membrane Phosphoprotein Reference proteome Repeat Signal Transmembrane Transmembrane helix | MKYGKVSFLA | MKYGKVSFLALLCSLYVRGSLADPESEQEPLVFNPTEVKAPLVEQFQGAWSERWIPSHAKRFVNGIEEMSYVGEWTVEESSGPGALKGEAGLVMKDEAAHHAISYEFDEPINEPEKDLVVQYEVNPEEGLNCGGAYLKLLAEPTHGEMSNSIDYRIMFGPDKCGVNDRVHFIFKHKNPLTGEYSEKHLDSRPASLLKPGITNLYTLIVKPDQTFEVRINGDVVRQGSLFYDFIPPVLPPVEIYDPEDIKPADWVDEPEIPDPNAVKPDDWDEDAPRMIPDPDAVKPEDWLEDEPLYIPDPEAQKPEDWDDEEDGDWIPSE... | protein folding ubiquitin-dependent ERAD pathway endoplasmic reticulum; endoplasmic reticulum membrane; fungal-type vacuole; membrane calcium ion binding carbohydrate binding unfolded protein binding Schizosaccharomyces pombe Calcium Chaperone Disulfide bond Endoplasmic reticulum Glycoprotein Lectin Membrane Phosphopr... |
intracellular signal transduction phosphorylation positive regulation of mitotic cytokinesis, division site positioning regulation of cell shape regulation of cell wall (1->3)-beta-D-glucan biosynthetic process | cell cortex of cell tip; cell division site; cytosol; division septum; mitotic actomyosin contractile ring; mitotic actomyosin contractile ring, intermediate layer; nucleus | ATP binding diacylglycerol-dependent, calcium-independent serine/threonine kinase activity lipid binding metal ion binding protein serine kinase activity protein serine/threonine kinase activity | Schizosaccharomyces pombe | ATP-binding Cell shape Coiled coil Cytoplasm Kinase Metal-binding Nucleotide-binding Phosphoprotein Reference proteome Repeat Serine/threonine-protein kinase Transferase Zinc Zinc-finger | MVQLDDALQD | MVQLDDALQDAYKKVEREESLILGAKAMVASTKNPEVKRRLESNIAVSENNIKYLRERIDALKVESGSERESQSDKDSSKKYSDSAKSTNSDDHLLSYNRSAFDLFNSEKPLSPEKISTMLQHLQMRLSIEQQCVSGIEKIMSLYSKEQKDKTDVIIKLKEGKQKVNLLKRSLKRYNELHIPFDISTPSSEEKQQASGLNFRGLAKPISGTLKVTIHSLRNIEHTSFLQTHSFTMPSYAVLYVDDAQVAKSRISQTDTWDETFIFDVHRAKEFQIIIYEKKKDFDIPIALILIPTTIIAEELRRKRNIQEMSETSWKPSI... | intracellular signal transduction phosphorylation positive regulation of mitotic cytokinesis, division site positioning regulation of cell shape regulation of cell wall (1->3)-beta-D-glucan biosynthetic process cell cortex of cell tip; cell division site; cytosol; division septum; mitotic actomyosin contractile ring; m... |
fungal-type cell wall biogenesis intracellular signal transduction negative regulation of glucose mediated signaling pathway phosphorylation regulation of cell wall (1->3)-beta-D-glucan biosynthetic process regulation of establishment or maintenance of cell polarity regulating cell shape regulation of fungal-type cell ... | cell division site; cell tip; division septum | ATP binding diacylglycerol-dependent serine/threonine kinase activity lipid binding metal ion binding protein serine kinase activity protein serine/threonine kinase activity | Schizosaccharomyces pombe | ATP-binding Cell shape Coiled coil Kinase Metal-binding Nucleotide-binding Phosphoprotein Reference proteome Repeat Serine/threonine-protein kinase Transferase Zinc Zinc-finger | MDMIDEAITE | MDMIDEAITEVVRKIERERSVIHGALSMKRLTQNQTVHQQLHSNIEESKKSIIYLEERLEKLKLRKNGVRKSNSEKPSVGIEKNPSFSTTKSAKSFSSTSSNIDSNLDLLNYDTPLTISKISFLLQQLEFKLSVEEQYRKGIEKMAKLYEREHDRRSIAEAEKKYVESAQKITLLKQALKRYHDLHIEIDEEDVPSTESRGNLNARRPQSGLLKITVGSLRNVTHSAGISKQTEMIVAIRAEDLERARTRPSRTDRFNETFEIDLEKTNEVEIVVYEKKNEKLLLPVGLLWIRLSDLVEKQRRKKVEQEVSDKGWVSADK... | fungal-type cell wall biogenesis intracellular signal transduction negative regulation of glucose mediated signaling pathway phosphorylation regulation of cell wall (1->3)-beta-D-glucan biosynthetic process regulation of establishment or maintenance of cell polarity regulating cell shape regulation of fungal-type cell ... |
DNA recombinase assembly double-strand break repair via homologous recombination double-strand break repair via single-strand annealing gene conversion at mating-type locus mating type switching mitotic recombination mitotic recombination-dependent replication fork processing replication fork processing stalled replica... | chromatin; nucleus; site of double-strand break | damaged DNA binding DNA end binding double-stranded DNA binding identical protein binding single-stranded DNA binding | Schizosaccharomyces pombe | DNA damage DNA recombination DNA repair Nucleus Phosphoprotein Reference proteome | MSFEQKQHVA | MSFEQKQHVASEDQGHFNTAYSHEEFNFLQSSLTRKLGPEYVSRRSGPGGFSVSYIESWKAIELANEIFGFNGWSSSIRSINVDFMDENKENGRISLGLSVIVRVTIKDGAYHEDIGYGSIDNCRGKASAFEKCKKEGTTDALKRALRNFGNSLGNCMYDKYYLREVGKMKPPTYHFDSGDLFRKTDPAARESFIKKQKTLNSTRTVNNQPLVNKGEQLAPRRAAELNDEQTREIEMYADEELDNIFVEDDIIAHLAVAEDTAHPAANNHHSEKAGTQINNKDKGSHNSAKPVQRSHTYPVAVPQNTSDSVGNAVTDTSP... | DNA recombinase assembly double-strand break repair via homologous recombination double-strand break repair via single-strand annealing gene conversion at mating-type locus mating type switching mitotic recombination mitotic recombination-dependent replication fork processing replication fork processing stalled replica... |
ergosterol biosynthetic process farnesyl diphosphate metabolic process isoprenoid biosynthetic process | endoplasmic reticulum; endoplasmic reticulum membrane; nuclear outer membrane-endoplasmic reticulum membrane network | farnesyl-diphosphate farnesyltransferase activity squalene synthase activity | Schizosaccharomyces pombe | Endoplasmic reticulum Isoprene biosynthesis Lipid biosynthesis Lipid metabolism Magnesium Membrane Multifunctional enzyme NADP Reference proteome Steroid biosynthesis Steroid metabolism Sterol biosynthesis Sterol metabolism Transferase Transmembrane Transmembrane helix | MSLANRIEEI | MSLANRIEEIRCLCQYKLWNDLPSYGEDENVPQNIRRCYQLLDMTSRSFAVVIKELPNGIREAVMIFYLVLRGLDTVEDDMTLPLDKKLPILRDFYKTIEVEGWTFNESGPNEKDRQLLVEFDVVIKEYLNLSEGYRNVISNITKEMGDGMAYYASLAEKNDGFSVETIEDFNKYCHYVAGLVGIGLSRLFAQSKLEDPDLAHSQAISNSLGLFLQKVNIIRDYREDFDDNRHFWPREIWSKYTSSFGDLCLPDNSEKALECLSDMTANALTHATDALVYLSQLKTQEIFNFCAIPQVMAIATLAAVFRNPDVFQTNVKI... | ergosterol biosynthetic process farnesyl diphosphate metabolic process isoprenoid biosynthetic process endoplasmic reticulum; endoplasmic reticulum membrane; nuclear outer membrane-endoplasmic reticulum membrane network farnesyl-diphosphate farnesyltransferase activity squalene synthase activity Schizosaccharomyces pom... |
thiamine biosynthetic process thiamine diphosphate biosynthetic process | cytosol; nucleus | 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP metal ion binding | Schizosaccharomyces pombe | Cytoplasm Iron Metal-binding Nucleus Pyridoxal phosphate Reference proteome Thiamine biosynthesis Transferase | MSTNKITFLT | MSTNKITFLTNWEATPYHLPIFLAQTRGYYEREGIEVAILEPTNPSDVTALIGSGKVDMGLKAMIHTLAAKARGYPVTSFGSLLNEPFTGLITLKGNGINDFKDIKGKRIGYVGEFGKIQLDDLCSKFGLSPSDYTAIRCGMNIAPAIINGEIDGGIGIECMQQVELERWCVSQGRPRSDVQMLRIDRLANLGCCCFCTILYIAHDEFIAKHPDKIKAFLRAIHSATLDMLKDPVQTYKEYIHFKREMGSELHREQFERCFAYFSHDISNVPRDWNKVTNYSKRLGIIPQDFEPNCTNGYLTWELDPDEKDPMGKQEAIA... | thiamine biosynthetic process thiamine diphosphate biosynthetic process cytosol; nucleus 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP metal ion binding Schizosaccharomyces pombe Cytoplasm Iron Metal-binding Nucleus Pyridoxal phosphate Reference proteome Thiamine biosynt... |
adenylate cyclase-activating G protein-coupled receptor signaling pathway cellular response to glucose starvation negative regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway positive regulation of protein export from nucleus regulation of protein phosphorylation | cAMP-dependent protein kinase complex; cytoplasm; cytosol; nucleus | cAMP binding cAMP-dependent protein kinase inhibitor activity protein kinase A catalytic subunit binding | Schizosaccharomyces pombe | cAMP cAMP-binding Nucleotide-binding Phosphoprotein Reference proteome Repeat | MSFEEVYEEL | MSFEEVYEELKALVDEQNPSDVLQFCYDFFGEKLKAERSVFRRGDTITESFSDGDESDFLSELNDMVAGPEAIGPDAKYVPELGGLKEMNVSYPQNYNLLRRQSVSTESMNPSAFALETKRTFPPKDPEDLKRLKRSVAGNFLFKNLDEEHYNEVLNAMTEKRIGEAGVAVIVQGAVGDYFYIVEQGEFDVYKRPELNITPEEVLSSGYGNYITTISPGEYFGELALMYNAPRAASVVSKTPNNVIYALDRTSFRRIVFENAYRQRMLYESLLEEVPILSSLDKYQRQKIADALQTVVYQAGSIVIRQGDIGNQFYLIED... | adenylate cyclase-activating G protein-coupled receptor signaling pathway cellular response to glucose starvation negative regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway positive regulation of protein export from nucleus regulation of protein phosphorylation cA... |
chromosome organization involved in meiotic cell cycle DNA recombinase assembly DNA recombination DNA strand invasion double-strand break repair involved in meiotic recombination double-strand break repair via homologous recombination mating type switching meiotic strand invasion mitotic recombination mitotic recombina... | chromatin; chromosome, centromeric region; condensed nuclear chromosome; nuclear envelope; nucleus; site of double-strand break | ATP binding ATP hydrolysis activity ATP-dependent activity, acting on DNA ATP-dependent DNA damage sensor activity DNA strand exchange activity double-stranded DNA binding identical protein binding single-stranded DNA binding Swi5-Sfr1 complex binding | Schizosaccharomyces pombe | ATP-binding DNA damage DNA recombination DNA repair DNA-binding Magnesium Nucleotide-binding Nucleus Reference proteome | MADTEVEMQV | MADTEVEMQVSAADTNNNENGQAQSNYEYDVNVQDEEDEAAAGPMPLQMLEGNGITASDIKKIHEAGYYTVESIAYTPKRQLLLIKGISEAKADKLLGEASKLVPMGFTTATEYHIRRSELITITTGSKQLDTLLQGGVETGSITELFGEFRTGKSQICHTLAVTCQLPIDMGGGEGKCLYIDTEGTFRPVRLLAVADRYGLNGEEVLDNVAYARAYNADHQLELLQQAANMMSESRFSLLVVDSCTALYRTDFSGRGELSARQMHLARFMRTLQRLADEFGIAVVITNQVVAQVDGISFNPDPKKPIGGNILAHSSTTR... | chromosome organization involved in meiotic cell cycle DNA recombinase assembly DNA recombination DNA strand invasion double-strand break repair involved in meiotic recombination double-strand break repair via homologous recombination mating type switching meiotic strand invasion mitotic recombination mitotic recombina... |
CDP metabolic process dCDP biosynthetic process deoxyribonucleotide biosynthetic process DNA replication dTTP biosynthetic process | cytoplasm; cytosol; ribonucleoside-diphosphate reductase complex | ATP binding ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor | Schizosaccharomyces pombe | Allosteric enzyme ATP-binding Deoxyribonucleotide synthesis Disulfide bond Nucleotide-binding Oxidoreductase Reference proteome | MFVYKRDGRQ | MFVYKRDGRQEKVAFDKITARVSRLCYGLDSDHVDPVEITQKVISGVYPGVTTIELDNLAAETAATMTTKHPDYAILAARIAVSNLHKQTEKVFSTVVQQLHDYVNPKTDKPAPMISDKIYDIVMKHKDELDSAIIYDRDFTYNFFGFKTLERSYLLRIDGKVAERPQHMIMRVAVGIHGEDIEAAIETYNLMSQRYFTHASPTLFNAGTPRPQLSSCFLVTMKDDSIEGIYDTLKMCAMISKTAGGIGINIHNIRATGSYIAGTNGTSNGIVPMIRVYNNTARYVDQGGNKRPGAFAAYLEPWHADVMDFLELRKTHGN... | CDP metabolic process dCDP biosynthetic process deoxyribonucleotide biosynthetic process DNA replication dTTP biosynthetic process cytoplasm; cytosol; ribonucleoside-diphosphate reductase complex ATP binding ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor Schizosaccharomyces pombe Allo... |
CDP metabolic process dCDP biosynthetic process purine deoxyribonucleoside triphosphate biosynthetic process purine nucleoside metabolic process pyrimidine deoxyribonucleoside triphosphate biosynthetic process pyrimidine nucleoside metabolic process | cytoplasm; cytosol; nucleus; ribonucleoside-diphosphate reductase complex | metal ion binding ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor | Schizosaccharomyces pombe | Cytoplasm Deoxyribonucleotide synthesis Iron Metal-binding Nucleus Oxidoreductase Reference proteome | MGLEHLEEFS | MGLEHLEEFSYPKEHGEEVEYDSEQGVRKIYVKSIKETFNFDNVSEEEKQEGGDYYLGKKEDELDEVVLRPNPHRFVLFPIKYHEIWQFYKKAEASFWTAEEIDLSKDLVDWDNKLNADERYFISTVLAYFAASDGIVNENLLERFSSEVQIPEARCVYGFQIMIENIHSETYSLLLDTYIREPKEKQRHFDAILTMGSIKAKAKWALRWINDEDSTYAIRLVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELICRDEGLHTDFACLMFSHLKHRPGRKVVEAIIVEAVDIEKEYFTDALPVSLLGMNKDLMCQY... | CDP metabolic process dCDP biosynthetic process purine deoxyribonucleoside triphosphate biosynthetic process purine nucleoside metabolic process pyrimidine deoxyribonucleoside triphosphate biosynthetic process pyrimidine nucleoside metabolic process cytoplasm; cytosol; nucleus; ribonucleoside-diphosphate reductase comp... |
chaperone cofactor-dependent protein refolding endoplasmic reticulum unfolded protein response IRE1-mediated unfolded protein response protein refolding ubiquitin-dependent ERAD pathway | cortical endoplasmic reticulum lumen; cytoplasm; endoplasmic reticulum; endoplasmic reticulum chaperone complex; endoplasmic reticulum lumen; membrane; nuclear membrane; nucleus; perinuclear endoplasmic reticulum lumen | ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone heat shock protein binding protein folding chaperone unfolded protein binding | Schizosaccharomyces pombe | ATP-binding Chaperone Endoplasmic reticulum Glycoprotein Hydrolase Nucleotide-binding Reference proteome Signal Stress response | MKKFQLFSIL | MKKFQLFSILSYFVALFLLPMAFASGDDNSTESYGTVIGIDLGTTYSCVAVMKNGRVEIIANDQGNRITPSYVAFTEDERLVGEAAKNQAPSNPENTIFDIKRLIGRKFDEKTMAKDIKSFPFHIVNDKNRPLVEVNVGGKKKKFTPEEISAMILSKMKQTAEAYLGKPVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVIRIVNEPTAAAIAYGLDKTDTEKHIVVYDLGGGTFDVSLLSIDNGVFEVLATSGDTHLGGEDFDNRVINYLARTYNRKNNVDVTKDLKAMGKLKREVEKAKRTLSSQKSVRIEIESFFNG... | chaperone cofactor-dependent protein refolding endoplasmic reticulum unfolded protein response IRE1-mediated unfolded protein response protein refolding ubiquitin-dependent ERAD pathway cortical endoplasmic reticulum lumen; cytoplasm; endoplasmic reticulum; endoplasmic reticulum chaperone complex; endoplasmic reticulum... |
intracellular pH reduction intracellular potassium ion homeostasis intracellular sodium ion homeostasis proton export across plasma membrane proton transmembrane transport regulation of membrane potential sodium ion export across plasma membrane sodium ion transmembrane transport | nuclear outer membrane-endoplasmic reticulum membrane network; perinuclear endoplasmic reticulum membrane; plasma membrane; plasma membrane of cell tip; prospore membrane | sodium:proton antiporter activity | Schizosaccharomyces pombe | 3D-structure Antiport Cell membrane Glycoprotein Ion transport Membrane Phosphoprotein Reference proteome Sodium Sodium transport Transmembrane Transmembrane helix Transport | MGWRQLDIDK | MGWRQLDIDKVHLALIVAGGFITFFCYFSEVFRKKLLVGEAVLGSITGLIFGPHAAKLVDPFSWGDHGDYLTVEICRIVLDVRVFASAIELPGAYFQHNFRSIIVMLLPVMAYGWLVTAGFAYALFPQINFLGSLLIAGCITSTDPVLSALIVGEGPLAKKTPERIRSLLIAESGCNDGMAVPFFYFAIKLLTVKPSRNAGRDWVLLVVLYECAFGIFFGCVIGYLLSFILKHAQKYRLIDAISYYSLPLAIPLLCSGIGTIIGVDDLLMSFFAGILFNWNDLFSKNISACSVPAFIDQTFSLLFFTYYGTIIPWNNFNW... | intracellular pH reduction intracellular potassium ion homeostasis intracellular sodium ion homeostasis proton export across plasma membrane proton transmembrane transport regulation of membrane potential sodium ion export across plasma membrane sodium ion transmembrane transport nuclear outer membrane-endoplasmic reti... |
cell cycle cell division regulation of transcription by RNA polymerase II transcription initiation at RNA polymerase II promoter | nucleus; transcription factor TFIIK complex | cyclin-dependent protein serine/threonine kinase activator activity cyclin-dependent protein serine/threonine kinase regulator activity protein serine/threonine kinase activator activity RNA polymerase II general transcription initiation factor activity | Schizosaccharomyces pombe | Cell cycle Cell division Cyclin Nucleus Phosphoprotein Reference proteome | MSADKFRDST | MSADKFRDSTHYRDWIFTEEDLSKTRAKVNEKFTNIVRERMLEELSLQNKEASLEVLPPTLTVEEELELVNYYSFQLNALSSALSLPTHIRSTAILFFKRFYLINSVMEYSPKIISFTSLFLATKCNDHYISIEQFCKNMPKTTPEEVLEYEFNVCQSLKWDLYVWLPFRPLQGFLLDCQTVLPKVAVEKFYECHDLSKKFLIETLHSDIYFLHSPSIIALGAIYHTNPTICLQYIEAKKIPELQPLIISISANLKATKKFKIEKKKAQDYGRKLYFCMNPLRNKSSALYLKRKAEEESTNNNKWAKKFSTSSNVLDKNP... | cell cycle cell division regulation of transcription by RNA polymerase II transcription initiation at RNA polymerase II promoter nucleus; transcription factor TFIIK complex cyclin-dependent protein serine/threonine kinase activator activity cyclin-dependent protein serine/threonine kinase regulator activity protein ser... |
cell division G1/S transition of mitotic cell cycle negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway regulation of cell shape regulation of TORC1 signaling | chromatin; cytoplasm; cytosol; nucleus; protein serine/threonine phosphatase complex | metal ion binding myosin phosphatase activity phosphoprotein phosphatase activity protein serine/threonine phosphatase activity | Schizosaccharomyces pombe | Cell cycle Cell division Cell shape Hydrolase Manganese Metal-binding Mitosis Nucleus Protein phosphatase Reference proteome | MFDLDEWIAT | MFDLDEWIATVRKCKYLPEHQLKRLCEMVKVILMEESNIQPVRTPVTVCGDIHGQFYDLLELFRVGGELPSTNYIFMGDFVDRGYFSLETFTLFMLLKARYPDKITLLRGNHESRQITQVYGFYDECQTKYGNANVWKYCCQVFDFLTLAAVIDNKILCVHGGLSPEVRTLDQIRILARAQEIPHEGSFCDLMWSDPEDIESWTVSPRGAGWLFGSKVTTEFSQINDLTLIARAHQLVQEGYKYHFADKNLVTVWSAPNYCYRCGNVASVMKVDESLEPEFRIFSAVADEDRTVPPSRKRSEYFI | cell division G1/S transition of mitotic cell cycle negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway regulation of cell shape regulation of TORC1 signaling chromatin; cytoplasm; cytosol; nucleus; protein serine/threonine phosphatase complex metal ion binding myosin phosphatase act... |
negative regulation of transcription by RNA polymerase II phosphorylation positive regulation of G2/M transition of mitotic cell cycle regulation of meiotic cell cycle signal transduction | cytoplasm; cytosol; nucleus | ATP binding cyclin-dependent protein serine/threonine kinase activity protein kinase activity protein serine kinase activity protein serine/threonine kinase activity | Schizosaccharomyces pombe | ATP-binding Kinase Nucleotide-binding Reference proteome Serine/threonine-protein kinase Transferase | MKSVGHFVPW | MKSVGHFVPWLTDIRHLTDGTISEVFVGERKNSKKLYVIKVQGLVFKRPPHDAMRGKLILESIGHPHIERIVDSFIDNEAGSVYLITSFKSFVLSDVMDEISIDTKCKIVLQISSALEYLEKHGILHRDIHPNNILLDSMNGPAYLSDFSIAWSKQHPGEEVQELIPQIGTGHYRAIETLFGCHSYGHEVDRWTFGILIAELFSNQALFDDGSSEGWPSELRLTSSIIQTLGTPNPSMWPELSTFPDWNKFIFHEYPPKPWSEILPSVDTSIQYIVSHLVTYSNRASPSFVIESFPKVSARLSQYA | negative regulation of transcription by RNA polymerase II phosphorylation positive regulation of G2/M transition of mitotic cell cycle regulation of meiotic cell cycle signal transduction cytoplasm; cytosol; nucleus ATP binding cyclin-dependent protein serine/threonine kinase activity protein kinase activity protein se... |
cell cycle cell division intracellular signal transduction peptidyl-serine phosphorylation positive regulation of mRNA splicing, via spliceosome positive regulation of protein export from nucleus positive regulation of protein import into nucleus regulation of mitotic nuclear division regulation of mRNA processing spli... | cell division site; cytoplasm; cytosol; mitotic spindle pole body; nucleus | ATP binding protein serine kinase activity protein serine/threonine kinase activity | Schizosaccharomyces pombe | ATP-binding Cell cycle Cell division Cytoplasm Kinase Mitosis Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MGSDGSSLSP | MGSDGSSLSPKVSQPGHTEIVDHVSEKVITNGKNVNKKVNAEVDGKSMVEKVKTHEENAEDYHYGGYHPVYIGEEFHHRRYVVERKLGWGHFSTVWLAYDRAAKRRVALKVVRSAEHYRETSIDEIRILQKIREGDEKHLGKKHIISLLDYFVHRGPNGAHVCMVFEVLGENLLSLIQSYGHRGVPVGIVKQIAYQLLIALDYLHRECGIIHTDLKPENVLICIDQDALQHIEAPATTSSPTSNTSSSKTRNNTGYTAKAPIIKRGQSVDNSAQERKTFAKNPTKNSKPAGQVIPSSPFTSTLSRFPSLEGAVSEISLRD... | cell cycle cell division intracellular signal transduction peptidyl-serine phosphorylation positive regulation of mRNA splicing, via spliceosome positive regulation of protein export from nucleus positive regulation of protein import into nucleus regulation of mitotic nuclear division regulation of mRNA processing spli... |
double-strand break repair via homologous recombination double-strand break repair via single-strand annealing double-strand break repair via single-strand annealing, removal of nonhomologous ends gene conversion at mating-type locus mating type switching nucleotide-excision repair nucleotide-excision repair involved i... | cytoplasm; mitotic spindle pole body; nucleotide-excision repair factor 1 complex; nucleus | 3' overhang single-stranded DNA endodeoxyribonuclease activity damaged DNA binding single-stranded DNA binding single-stranded DNA endodeoxyribonuclease activity | Schizosaccharomyces pombe | Cytoplasm Cytoskeleton DNA damage DNA repair DNA-binding Endonuclease Hydrolase Nuclease Nucleus Phosphoprotein Reference proteome | METKVHLPLA | METKVHLPLAYQQQVFNELIEEDGLCVIAPGLSLLQIAANVLSYFAVPGSLLLLVGANVDDIELIQHEMESHLEKKLITVNTETMSVDKREKSYLEGGIFAITSRILVMDLLTKIIPTEKITGIVLLHADRVVSTGTVAFIMRLYRETNKTGFIKAFSDDPEQFLMGINALSHCLRCLFLRHVFIYPRFHVVVAESLEKSPANVVELNVNLSDSQKTIQSCLLTCIESTMRELRRLNSAYLDMEDWNIESALHRSFDVIVRRQLDSVWHRVSPKTKQLVGDLSTLKFLLSALVCYDCVSFLKLLDTLVLSVNVSSYPSNA... | double-strand break repair via homologous recombination double-strand break repair via single-strand annealing double-strand break repair via single-strand annealing, removal of nonhomologous ends gene conversion at mating-type locus mating type switching nucleotide-excision repair nucleotide-excision repair involved i... |
actin filament organization adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway cAMP-mediated signaling negative regulation of cell growth negative regulation of conjugation with cellular fusion | cell septum; cytoplasm; division septum; growing cell tip | actin binding adenylate cyclase binding | Schizosaccharomyces pombe | Phosphoprotein Reference proteome | MSDMINIRET | MSDMINIRETGYNFTTILKRLEAATSRLEDLVESGHKPLPNMHRPSRDSNSQTHNISFNIGTPTAPTVSTGSPAVASLHDQVAAAISPRNRSLTSTSAVEAVPASISAYDEFCSKYLSKYMELSKKIGGLIAEQSEHVEKAFNLLRQVLSVALKAQKPDMDSPELLEFLKPIQSELLTITNIRDEHRTAPEFNQLSTVMSGISILGWVTVEPTPLSFMSEMKDSSQFYANRVMKEFKGKDDLQIEWVRSYLTLLTELITYVKTHFKTGLTWSTKQDAVPLKTALANLSASKTQAPSSGDSANGGLPPPPPPPPPSNDFWK... | actin filament organization adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway cAMP-mediated signaling negative regulation of cell growth negative regulation of conjugation with cellular fusion cell septum; cytoplasm; division septum; growing cell tip actin binding adenylate cyc... |
canonical glycolysis gluconeogenesis | cytosol; nucleus | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity phosphoglycerate mutase activity | Schizosaccharomyces pombe | 3D-structure Direct protein sequencing Glycolysis Isomerase Phosphoprotein Reference proteome | MTTEAAPNLL | MTTEAAPNLLVLTRHGESEWNKLNLFTGWKDPALSETGIKEAKLGGERLKSRGYKFDIAFTSALQRAQKTCQIILEEVGEPNLETIKSEKLNERYYGDLQGLNKDDARKKWGAEQVQIWRRSYDIAPPNGESLKDTAERVLPYYKSTIVPHILKGEKVLIAAHGNSLRALIMDLEGLTGDQIVKRELATGVPIVYHLDKDGKYVSKELIDN | canonical glycolysis gluconeogenesis cytosol; nucleus 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity phosphoglycerate mutase activity Schizosaccharomyces pombe 3D-structure Direct protein sequencing Glycolysis Isomerase Phosphoprotein Reference proteome MTTEAAPNLL MTTEAAPNLLVLTRHGESEWNKLNLFTGWKDPAL... |
chromatin looping homologous chromosome pairing at meiosis meiotic centromeric cohesion protection in anaphase I meiotic sister chromatid cohesion involved in meiosis I sister chromatid cohesion spindle attachment to meiosis I kinetochore | chromatin; cohesin complex; inner kinetochore; meiotic cohesin complex; meiotic spindle; nuclear chromosome; nucleus; pericentric heterochromatin | chromatin binding | Schizosaccharomyces pombe | Chromosome Meiosis Nucleus Phosphoprotein Reference proteome | MFYNQDVLTK | MFYNQDVLTKEKGGMGVIWLAATLGSKHSLRKLHKKDIMSVDIDEACDFVAFSPEPLALRLSSNLMIGVTRVWAHQYSFFHSQVSTLHLRVRKELDHFTSKPFKNIDIQNEQTNPKQLLLAEDPAFIPEVSLYDAFNLPSVDLHVDMSSFTQPKENPNISVLETLPDSTSYLINTSQNYSLRNNVSSFVYEDSRAFSTEEPLDFEFDENGDIQELTKGTINSDPSLQAASQHSNLGSVQREYNSEEQESRIHMFEIDEDVLPLPVPLQSVMDSEHNENEPRALKRRKVQKLLEPDENIELSTRTLSQWRKNYVERMIALE... | chromatin looping homologous chromosome pairing at meiosis meiotic centromeric cohesion protection in anaphase I meiotic sister chromatid cohesion involved in meiosis I sister chromatid cohesion spindle attachment to meiosis I kinetochore chromatin; cohesin complex; inner kinetochore; meiotic cohesin complex; meiotic s... |
mRNA branch site recognition mRNA cis splicing, via spliceosome spliceosomal complex assembly | commitment complex; nuclear speck; nucleus; U2-type prespliceosome; U2AF complex | mRNA binding poly-pyrimidine tract binding pre-mRNA 3'-splice site binding | Schizosaccharomyces pombe | 3D-structure mRNA processing mRNA splicing Nucleus Reference proteome Repeat RNA-binding | MDLSSRLSSG | MDLSSRLSSGSSRIPKRHRDYRDEEPRRERGSGGIGREDPRGHYGSERPRRRRRDESDFRRHRESRERSYREDERPRRERRYDDYEPRSLRYSSVGRSRSPPPSRERSVRSIEQELEQLRDVTPINQWKRKRSLWDIKPPGYELVTADQAKMSGVFPLPGAPRAAVTDPEKLLEFARSAEGSIIAPPPPLQPGASRQARRLVVTGIPNEFVEDAFVSFIEDLFISTTYHKPETKHFSSVNVCKEENFAILEVATPEDATFLWGLQSESYSNDVFLKFQRIQNYIVPQITPEVSQKRSDDYAKNDVLDSKDKIYISNLPLN... | mRNA branch site recognition mRNA cis splicing, via spliceosome spliceosomal complex assembly commitment complex; nuclear speck; nucleus; U2-type prespliceosome; U2AF complex mRNA binding poly-pyrimidine tract binding pre-mRNA 3'-splice site binding Schizosaccharomyces pombe 3D-structure mRNA processing mRNA splicing ... |
cell division DNA recombination G1/S transition of mitotic cell cycle mitotic cell cycle phase transition mitotic G1 cell size control checkpoint signaling negative regulation of conjugation with cellular fusion positive regulation of G1/S transition of mitotic cell cycle regulation of cell cycle switching, mitotic to ... | chromatin; cyclin-dependent protein kinase holoenzyme complex; cytoplasm; mitotic spindle pole body; nucleus; spindle pole body | cyclin-dependent protein serine/threonine kinase activator activity cyclin-dependent protein serine/threonine kinase regulator activity | Schizosaccharomyces pombe | Cell cycle Cell division Conjugation Cyclin Cytoplasm Cytoskeleton Mitosis Nucleus Phosphoprotein Reference proteome | MALYSISKPV | MALYSISKPVGSKINKHSYQDENTLVGKQALSKGTEKTKLSTNFEINLPRRTVLSDVSNVGKNNADEKDTKKAKRSFDESNLSTNEEADKPVESKFVKKLKVYSKNADPSVETLQKDRVSNVDDHLSSNPLMAEEYAPEIFEYIRKLDLKCLPNPKYMDQQKELTWKMREILNEWLVEIHSNFCLMPETLYLAVNIIDRFLSRRSCSLSKFQLTGITALLIASKYEEVMCPSIQNFVYMTDGAFTVEDVCVAERYMLNVLNFDLSYPSPLNFLRKISQAEGYDAQTRTLGKYLTEIYLFDHDLLRYPMSKIAAAAMYLSR... | cell division DNA recombination G1/S transition of mitotic cell cycle mitotic cell cycle phase transition mitotic G1 cell size control checkpoint signaling negative regulation of conjugation with cellular fusion positive regulation of G1/S transition of mitotic cell cycle regulation of cell cycle switching, mitotic to ... |
induction of conjugation with cellular fusion positive regulation of induction of conjugation with cellular fusion positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II | cytoplasm; cytosol; nucleus; RNA polymerase II transcription regulator complex; Tor2-Mei2-Ste11 complex | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific double-stranded DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA po... | Schizosaccharomyces pombe | Activator Cytoplasm DNA-binding Nucleus Phosphoprotein Reference proteome Stress response Transcription Transcription regulation | MSASLTAEQK | MSASLTAEQKDQKSSVKRPLNSFMLYRRDRQAEIPTSNHQSISRIIGQLWRNESAQVKKYYSDLSALERQKHMLENPEYKYTPKKRSTVRRRHKKVSPSSGSFVASDYVVLQQIAQSSKTLKQTEPEKPVNEEETLAALLAPALSYPKSGKSNLIETSELSCLSSSPMIRSHTIPSLSFTDQVSTTISTLDKSEQAPSSLGIYYRSPSSGSPIGRTKSVCLANKARIVPKRSMSSDGCVDKSYQMSKTPSLEANLPQNSSNCSARRVPKFDSKGTVSEQSNSDSPELSADKVLSHCSPIDARPSTPSCPNASISPKTPNT... | induction of conjugation with cellular fusion positive regulation of induction of conjugation with cellular fusion positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II cytoplasm; cytosol; nucleus; RNA polymerase II transcription regulator complex; Tor2-Mei2-Ste11 co... |
DNA protection DNA repair male gonad development purine nucleoside catabolic process response to cadmium ion response to oxidative stress | acrosomal vesicle; cytoplasm; cytosol; extracellular space; mitochondrial matrix; mitochondrion; nuclear membrane; nucleus | 2-hydroxy-ATP hydrolase activity 2-hydroxy-dATP hydrolase activity 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity ATP diphosphatase activity dATP diphosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-co... | Homo sapiens | 3D-structure Alternative initiation Cytoplasm Direct protein sequencing Hydrolase Magnesium Metal-binding Mitochondrion Nucleus Reference proteome RNA-binding Transit peptide | MGASRLYTLV | MGASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVESDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDTV | DNA protection DNA repair male gonad development purine nucleoside catabolic process response to cadmium ion response to oxidative stress acrosomal vesicle; cytoplasm; cytosol; extracellular space; mitochondrial matrix; mitochondrion; nuclear membrane; nucleus 2-hydroxy-ATP hydrolase activity 2-hydroxy-dATP hydrolase a... |
detoxification of copper ion response to copper ion | outer membrane-bounded periplasmic space; periplasmic space | copper ion binding ferroxidase activity oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor oxidoreductase activity, acting on metal ions oxidoreductase activity, acting on metal ions, oxygen as acceptor | Escherichia coli | 3D-structure Copper Direct protein sequencing Metal-binding Oxidoreductase Periplasm Reference proteome Repeat Signal | MQRRDFLKYS | MQRRDFLKYSVALGVASALPLWSRAVFAAERPTLPIPDLLTTDARNRIQLTIGAGQSTFGGKTATTWGYNGNLLGPAVKLQRGKAVTVDIYNQLTEETTLHWHGLEVPGEVDGGPQGIIPPGGKRSVTLNVDQPAATCWFHPHQHGKTGRQVAMGLAGLVVIEDDEILKLMLPKQWGIDDVPVIVQDKKFSADGQIDYQLDVMTAAVGWFGDTLLTNGAIYPQHAAPRGWLRLRLLNGCNARSLNFATSDNRPLYVIASDGGLLPEPVKVSELPVLMGERFEVLVEVNDNKPFDLVTLPVSQMGMAIAPFDKPHPVMRIQ... | detoxification of copper ion response to copper ion outer membrane-bounded periplasmic space; periplasmic space copper ion binding ferroxidase activity oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor oxidoreductase activity, acting on metal ions oxidoreductase activity,... |
cell redox homeostasis cytochrome complex assembly response to copper ion | plasma membrane | electron transfer activity protein-disulfide reductase (NAD(P)) activity protein-disulfide reductase activity | Escherichia coli | 3D-structure Cell inner membrane Cell membrane Cytochrome c-type biogenesis Direct protein sequencing Disulfide bond Electron transport Membrane NAD Oxidoreductase Redox-active center Reference proteome Signal Transmembrane Transmembrane helix Transport | MAQRIFTLIL | MAQRIFTLILLLCSTSVFAGLFDAPGRSQFVPADQAFAFDFQQNQHDLNLTWQIKDGYYLYRKQIRITPEHAKIADVQLPQGVWHEDEFYGKSEIYRDRLTLPVTINQASAGATLTVTYQGCADAGFCYPPETKTVPLSEVVANNAAPQPVSVPQQEQPTAQLPFSALWALLIGIGIAFTPCVLPMYPLISGIVLGGKQRLSTARALLLTFIYVQGMALTYTALGLVVAAAGLQFQAALQHPYVLIGLAIVFTLLAMSMFGLFTLQLPSSLQTRLTLMSNRQQGGSPGGVFVMGAIAGLICSPCTTAPLSAILLYIAQSG... | cell redox homeostasis cytochrome complex assembly response to copper ion plasma membrane electron transfer activity protein-disulfide reductase (NAD(P)) activity protein-disulfide reductase activity Escherichia coli 3D-structure Cell inner membrane Cell membrane Cytochrome c-type biogenesis Direct protein sequencing D... |
phosphoenolpyruvate-dependent sugar phosphotransferase system phosphorylation trehalose transport | plasma membrane | kinase activity protein-N(PI)-phosphohistidine-sugar phosphotransferase activity protein-phosphocysteine-trehalose phosphotransferase system transporter activity trehalose transmembrane transporter activity | Escherichia coli | Cell inner membrane Cell membrane Kinase Membrane Phosphoprotein Phosphotransferase system Reference proteome Sugar transport Transferase Transmembrane Transmembrane helix Transport | MMSKINQTDI | MMSKINQTDIDRLIELVGGRGNIATVSHCITRLRFVLNQPANARPKEIEQLPMVKGCFTNAGQFQVVIGTNVGDYYQALIASTGQAQVDKEQVKKAARHNMKWHEQLISHFAVIFFPLLPALISGGLILGFRNVIGDLPMSNGQTLAQMYPSLQTIYDFLWLIGEAIFFYLPVGICWSAVKKMGGTPILGIVLGVTLVSPQLMNAYLLGQQLPEVWDFGMFSIAKVGYQAQVIPALLAGLALGVIETRLKRIVPDYLYLVVVPVCSLILAVFLAHALIGPFGRMIGDGVAFAVRHLMTGSFAPIGAALFGFLYAPLVITG... | phosphoenolpyruvate-dependent sugar phosphotransferase system phosphorylation trehalose transport plasma membrane kinase activity protein-N(PI)-phosphohistidine-sugar phosphotransferase activity protein-phosphocysteine-trehalose phosphotransferase system transporter activity trehalose transmembrane transporter activity... |
division septum assembly FtsZ-dependent cytokinesis | cell division site; cytosol | identical protein binding protein homodimerization activity | Escherichia coli | 3D-structure Cell cycle Cell division Cytoplasm Reference proteome Septation | MQTQVLFEHP | MQTQVLFEHPLNEKMRTWLRIEFLIQQLTVNLPIVDHAGALHFFRNVSELLDVFERGEVRTELLKELDRQQRKLQTWIGVPGVDQSRIEALIQQLKAAGSVLISAPRIGQFLREDRLIALVRQRLSIPGGCCSFDLPTLHIWLHLPQAQRDSQVETWIASLNPLTQALTMVLDLIRQSAPFRKQTSLNGFYQDNGGDADLLRLNLSLDSQLYPQISGHKSRFAIRFMPLDTENGQVPERLDFELACC | division septum assembly FtsZ-dependent cytokinesis cell division site; cytosol identical protein binding protein homodimerization activity Escherichia coli 3D-structure Cell cycle Cell division Cytoplasm Reference proteome Septation MQTQVLFEHP MQTQVLFEHPLNEKMRTWLRIEFLIQQLTVNLPIVDHAGALHFFRNVSELLDVFERGEVRTELLKELDRQQRKLQ... |
glyoxylate cycle propionate catabolic process, 2-methylcitrate cycle regulation of translation tricarboxylic acid cycle | cytosol | 2-methylisocitrate dehydratase activity 4 iron, 4 sulfur cluster binding aconitate hydratase activity metal ion binding mRNA 3'-UTR binding mRNA binding | Escherichia coli | 3D-structure 4Fe-4S Direct protein sequencing Iron Iron-sulfur Lyase Metal-binding Reference proteome RNA-binding Tricarboxylic acid cycle | MLEEYRKHVA | MLEEYRKHVAERAAEGIAPKPLDANQMAALVELLKNPPAGEEEFLLDLLTNRVPPGVDEAAYVKAGFLAAIAKGEAKSPLLTPEKAIELLGTMQGGYNIHPLIDALDDAKLAPIAAKALSHTLLMFDNFYDVEEKAKAGNEYAKQVMQSWADAEWFLNRPALAEKLTVTVFKVTGETNTDDLSPAPDAWSRPDIPLHALAMLKNAREGIEPDQPGVVGPIKQIEALQQKGFPLAYVGDVVGTGSSRKSATNSVLWFMGDDIPHVPNKRGGGLCLGGKIAPIFFNTMEDAGALPIEVDVSNLNMGDVIDVYPYKGEVRNHE... | glyoxylate cycle propionate catabolic process, 2-methylcitrate cycle regulation of translation tricarboxylic acid cycle cytosol 2-methylisocitrate dehydratase activity 4 iron, 4 sulfur cluster binding aconitate hydratase activity metal ion binding mRNA 3'-UTR binding mRNA binding Escherichia coli 3D-structure 4Fe-4S Di... |
cellular response to oxidative stress chaperone-mediated protein complex assembly mitochondrial DNA metabolic process mitochondrial genome maintenance mitochondrion organization negative regulation of insulin receptor signaling pathway oxidation-dependent protein catabolic process protein catabolic process protein qual... | cytosol; membrane; mitochondrial matrix; mitochondrial nucleoid; mitochondrion; nucleoplasm | ADP binding ATP binding ATP hydrolysis activity ATP-dependent peptidase activity DNA polymerase binding G-quadruplex DNA binding identical protein binding insulin receptor substrate binding PH domain binding sequence-specific DNA binding serine-type endopeptidase activity single-stranded DNA binding single-stranded RNA... | Homo sapiens | 3D-structure Alternative splicing ATP-binding Cataract Deafness Disease variant DNA-binding Dwarfism Hydrolase Mitochondrion Nucleotide-binding Protease Reference proteome Serine protease Transit peptide | MAASTGYVRL | MAASTGYVRLWGAARCWVLRRPMLAAAGGRVPTAAGAWLLRGQRTCDASPPWALWGRGPAIGGQWRGFWEASSRGGGAFSGGEDASEGGAEEGAGGAGGSAGAGEGPVITALTPMTIPDVFPHLPLIAITRNPVFPRFIKIIEVKNKKLVELLRRKVRLAQPYVGVFLKRDDSNESDVVESLDEIYHTGTFAQIHEMQDLGDKLRMIVMGHRRVHISRQLEVEPEEPEAENKHKPRRKSKRGKKEAEDELSARHPAELAMEPTPELPAEVLMVEVENVVHEDFQVTEEVKALTAEIVKTIRDIIALNPLYRESVLQMMQA... | cellular response to oxidative stress chaperone-mediated protein complex assembly mitochondrial DNA metabolic process mitochondrial genome maintenance mitochondrion organization negative regulation of insulin receptor signaling pathway oxidation-dependent protein catabolic process protein catabolic process protein qual... |
dipeptide import across plasma membrane protein transport tripeptide import across plasma membrane | apical plasma membrane; membrane | dipeptide transmembrane transporter activity peptide:proton symporter activity tripeptide transmembrane transporter activity | Oryctolagus cuniculus | Cell membrane Glycoprotein Membrane Peptide transport Protein transport Reference proteome Symport Transmembrane Transmembrane helix Transport | MGMSKSLSCF | MGMSKSLSCFGYPLSIFFIVVNEFCERFSYYGMRALLILYFRNFIGWDDNLSTVIYHTFVALCYLTPILGALIADAWLGKFKTIVWLSIVYTIGQAVTSLSSVNELTDNNHDGTPDSLPVHVAVCMIGLLLIALGTGGIKPCVSAFGGDQFEEGQEKQRNRFFSIFYLAINAGSLLSTIITPMVRVQQCGIHVKQACYPLAFGIPAILMAVSLIVFIIGSGMYKKFKPQGNILSKVVKCICFAIKNRFRHRSKQFPKRAHWLDWAKEKYDERLIAQIKMVTRVLFLYIPLPMFWALFDQQGSRWTLQATTMSGRIGILEI... | dipeptide import across plasma membrane protein transport tripeptide import across plasma membrane apical plasma membrane; membrane dipeptide transmembrane transporter activity peptide:proton symporter activity tripeptide transmembrane transporter activity Oryctolagus cuniculus Cell membrane Glycoprotein Membrane Pepti... |
dipeptide transmembrane transport protein transport proton transmembrane transport tripeptide transmembrane transport | membrane; plasma membrane | dipeptide transmembrane transporter activity peptide:proton symporter activity proton transmembrane transporter activity tripeptide transmembrane transporter activity | Escherichia coli | 3D-structure Cell inner membrane Cell membrane Membrane Peptide transport Protein transport Reference proteome Transmembrane Transmembrane helix Transport | MNTTTPMGML | MNTTTPMGMLQQPRPFFMIFFVELWERFGYYGVQGVLAVFFVKQLGFSQEQAFVTFGAFAALVYGLISIGGYVGDHLLGTKRTIVLGALVLAIGYFMTGMSLLKPDLIFIALGTIAVGNGLFKANPASLLSKCYPPKDPRLDGAFTLFYMSINIGSLIALSLAPVIADRFGYSVTYNLCGAGLIIALLVYIACRGMVKDIGSEPDFRPMSFSKLLYVLLGSVVMIFVCAWLMHNVEVANLVLIVLSIVVTIIFFRQAFKLDKTGRNKMFVAFVLMLEAVVFYILYAQMPTSLNFFAINNVHHEILGFSINPVSFQALNPF... | dipeptide transmembrane transport protein transport proton transmembrane transport tripeptide transmembrane transport membrane; plasma membrane dipeptide transmembrane transporter activity peptide:proton symporter activity proton transmembrane transporter activity tripeptide transmembrane transporter activity Escherich... |
apoptotic process cell cycle cell division cellular response to exogenous dsRNA cellular response to starvation positive regulation of autophagosome assembly positive regulation of epidermal growth factor receptor signaling pathway positive regulation of protein phosphorylation Ras protein signal transduction receptor ... | cytosol; midbody; plasma membrane | ATPase binding G protein activity GDP binding GTP binding GTPase activity ubiquitin protein ligase binding | Rattus norvegicus | Apoptosis Cell cycle Cell division Cell membrane GTP-binding Hydrolase Lipoprotein Membrane Methylation Nucleotide-binding Prenylation Reference proteome | MAANKGKSQG | MAANKGKSQGSLVLHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKAEEDKIPLLVVGNKSDLEERRQVPVEEARGKAEEWGVQYVETSAKTRANVDKVFFDLMREIRAKKMSENKDKNGRKSGKSKKSFKERCCLL | apoptotic process cell cycle cell division cellular response to exogenous dsRNA cellular response to starvation positive regulation of autophagosome assembly positive regulation of epidermal growth factor receptor signaling pathway positive regulation of protein phosphorylation Ras protein signal transduction receptor ... |
carbohydrate metabolic process gluconeogenesis glucose metabolic process glycolytic process | cytoplasm; cytosol; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; tertiary granule lumen | magnesium ion binding phosphoglucomutase activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Carbohydrate metabolism Congenital disorder of glycosylation Cytoplasm Disease variant Glucose metabolism Glycogen storage disease Isomerase Magnesium Metal-binding Phosphoprotein Reference proteome | MVKIVTVKTQ | MVKIVTVKTQAYQDQKPGTSGLRKRVKVFQSSANYAENFIQSIISTVEPAQRQEATLVVGGDGRFYMKEAIQLIARIAAANGIGRLVIGQNGILSTPAVSCIIRKIKAIGGIILTASHNPGGPNGDFGIKFNISNGGPAPEAITDKIFQISKTIEEYAVCPDLKVDLGVLGKQQFDLENKFKPFTVEIVDSVEAYATMLRSIFDFSALKELLSGPNRLKIRIDAMHGVVGPYVKKILCEELGAPANSAVNCVPLEDFGGHHPDPNLTYAADLVETMKSGEHDFGAAFDGDGDRNMILGKHGFFVNPSDSVAVIAANIFSI... | carbohydrate metabolic process gluconeogenesis glucose metabolic process glycolytic process cytoplasm; cytosol; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; tertiary granule lumen magnesium ion binding phosphoglucomutase activity Homo sapiens 3D-structure Acetylation Alternative splicing C... |
centrosome cycle imaginal disc pattern formation maintenance of neuroblast polarity metaphase/anaphase transition of mitotic cell cycle mitotic cell cycle negative regulation of neuroblast proliferation positive regulation of canonical Wnt signaling pathway positive regulation of smoothened signaling pathway positive r... | cytosol; nucleus; protein phosphatase type 2A complex | protein phosphatase regulator activity | Drosophila melanogaster | Alternative splicing Reference proteome Repeat WD repeat | MGRWGRQSPV | MGRWGRQSPVLEPPDPQMQTTPPPPTLPPRTFMRQSSITKIGNMLNTAININGAKKPASNGEASWCFSQIKGALDDDVTDADIISCVEFNHDGELLATGDKGGRVVIFQRDPASKAANPRRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLQQKNPVHFLLSTNDKTVKLWKVSERDKSFGGYNTKEENGLIRDPQNVTALRVPSVKQIPLLVEASPRRTFANAHTYHINSISVNSDQETFLSADDLRINLWHLEVVNQSYNIVDIKPTNMEELTEVITAAEFHPTECNVFVYSSSKGTIRLCDMRSAALCDRHSK... | centrosome cycle imaginal disc pattern formation maintenance of neuroblast polarity metaphase/anaphase transition of mitotic cell cycle mitotic cell cycle negative regulation of neuroblast proliferation positive regulation of canonical Wnt signaling pathway positive regulation of smoothened signaling pathway positive r... |
blastocyst development cell cycle cell division circadian regulation of gene expression entrainment of circadian clock by photoperiod glycogen metabolic process MAPK cascade neuron differentiation positive regulation of glial cell proliferation protein dephosphorylation regulation of circadian rhythm regulation of nucl... | cleavage furrow; cytoplasm; cytosol; dendritic spine; focal adhesion; glutamatergic synapse; kinetochore; microtubule organizing center; midbody; mitochondrial outer membrane; mitochondrion; nuclear speck; nucleolus; nucleus; presynapse; protein-containing complex; PTW/PP1 phosphatase complex | lamin binding metal ion binding myosin phosphatase activity phosphatase activity phosphoprotein phosphatase activity protein domain specific binding protein kinase binding protein phosphatase 1 binding protein serine/threonine phosphatase activity protein-containing complex binding RNA binding | Homo sapiens | 3D-structure Acetylation Alternative splicing Biological rhythms Carbohydrate metabolism Cell cycle Cell division Centromere Chromosome Cytoplasm Cytoskeleton Direct protein sequencing Disulfide bond Glycogen metabolism Hydrolase Kinetochore Manganese Metal-binding Mitochondrion Nucleus Phosphoprotein Protein phosphata... | MADLDKLNID | MADLDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKKPNATRPVTPPRGMITKQ... | blastocyst development cell cycle cell division circadian regulation of gene expression entrainment of circadian clock by photoperiod glycogen metabolic process MAPK cascade neuron differentiation positive regulation of glial cell proliferation protein dephosphorylation regulation of circadian rhythm regulation of nucl... |
cell division glycogen metabolic process mitotic nuclear membrane reassembly protein dephosphorylation | cleavage furrow; kinetochore; membrane; midbody; mitochondrion; nuclear speck; nucleolus | metal ion binding myosin phosphatase activity protein serine/threonine phosphatase activity | Xenopus laevis | Carbohydrate metabolism Cell cycle Cell division Centromere Chromosome Cytoplasm Glycogen metabolism Hydrolase Kinetochore Manganese Membrane Metal-binding Mitochondrion Mitosis Nucleus Protein phosphatase Reference proteome | MADVDKLNID | MADVDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKKPNASRPVTPPRGMITKQ... | cell division glycogen metabolic process mitotic nuclear membrane reassembly protein dephosphorylation cleavage furrow; kinetochore; membrane; midbody; mitochondrion; nuclear speck; nucleolus metal ion binding myosin phosphatase activity protein serine/threonine phosphatase activity Xenopus laevis Carbohydrate metaboli... |
mitochondrial fission mitochondrial fragmentation involved in apoptotic process neuron differentiation positive regulation of neuron apoptotic process protein targeting to mitochondrion regulation of phosphoprotein phosphatase activity spermatid development | cytoplasm; cytoskeleton; cytosol; mitochondrial outer membrane; mitochondrion; protein phosphatase type 2A complex | protein phosphatase regulator activity protein-containing complex binding | Rattus norvegicus | Alternative splicing Apoptosis Cytoplasm Cytoskeleton Membrane Mitochondrion Mitochondrion outer membrane Phosphoprotein Reference proteome Repeat WD repeat | MEEDIDTRKI | MEEDIDTRKINNSFLRDHSYATEADIISTVEFNHTGELLATGDKGGRVVIFQREQESKNQVHRRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAYFLLSTNDKTVKLWKVSERDKRPEGYNLKDEEGRLRDPATITTLRVPVLRPMDLMVEATPRRVFANAHTYHINSISVNSDYETYMSADDLRINLWNFEITNQSFNIVDIKPANMEELTEVITAAEFHPHHCNTFVYSSSKGTIRLCDMRASALCDRHTKFFEEPEDPSNRSFFSEIISSISDVKFSHSGRYIMTRDYLTAKVWDLNMENRPVETYQ... | mitochondrial fission mitochondrial fragmentation involved in apoptotic process neuron differentiation positive regulation of neuron apoptotic process protein targeting to mitochondrion regulation of phosphoprotein phosphatase activity spermatid development cytoplasm; cytoskeleton; cytosol; mitochondrial outer membrane... |
cellular response to heat negative regulation of meiotic cell cycle process involved in oocyte maturation negative regulation of TORC1 signaling phosphorylation protein kinase A signaling | acrosomal vesicle; cAMP-dependent protein kinase complex; cytoplasm; cytosol; germinal vesicle; mitochondrion; nucleus; perinuclear region of cytoplasm; plasma membrane; sperm flagellum | AMP-activated protein kinase activity ATP binding cAMP-dependent protein kinase activity protein kinase A regulatory subunit binding protein serine kinase activity protein serine/threonine kinase activity | Sus scrofa | 3D-structure ATP-binding cAMP Cell membrane Cytoplasm Direct protein sequencing Kinase Lipoprotein Membrane Mitochondrion Myristate Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MGNAAAAKKG | MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFK... | cellular response to heat negative regulation of meiotic cell cycle process involved in oocyte maturation negative regulation of TORC1 signaling phosphorylation protein kinase A signaling acrosomal vesicle; cAMP-dependent protein kinase complex; cytoplasm; cytosol; germinal vesicle; mitochondrion; nucleus; perinuclear ... |
animal organ regeneration B cell differentiation cellular response to cytokine stimulus cellular response to glucocorticoid stimulus common myeloid progenitor cell proliferation cytokine-mediated signaling pathway dendritic cell differentiation hemopoiesis leukocyte homeostasis lymphocyte proliferation myeloid progenit... | endoplasmic reticulum; endoplasmic reticulum lumen; endosome membrane; plasma membrane; receptor complex | ATP binding cytokine receptor activity growth factor binding nuclear glucocorticoid receptor binding phosphatidylinositol 3-kinase activator activity protein self-association protein tyrosine kinase activity protein-containing complex binding transmembrane receptor protein tyrosine kinase activity vascular endothelial ... | Homo sapiens | 3D-structure Alternative splicing ATP-binding Disease variant Disulfide bond Endoplasmic reticulum Glycoprotein Host-virus interaction Immunoglobulin domain Kinase Membrane Nucleotide-binding Phosphoprotein Proto-oncogene Receptor Reference proteome Signal Transferase Transmembrane Transmembrane helix Tyrosine-protein ... | MPALARDGGQ | MPALARDGGQLPLLVVFSAMIFGTITNQDLPVIKCVLINHKNNDSSVGKSSSYPMVSESPEDLGCALRPQSSGTVYEAAAVEVDVSASITLQVLVDAPGNISCLWVFKHSSLNCQPHFDLQNRGVVSMVILKMTETQAGEYLLFIQSEATNYTILFTVSIRNTLLYTLRRPYFRKMENQDALVCISESVPEPIVEWVLCDSQGESCKEESPAVVKKEEKVLHELFGTDIRCCARNELGRECTRLFTIDLNQTPQTTLPQLFLKVGEPLWIRCKAVHVNHGFGLTWELENKALEEGNYFEMSTYSTNRTMIRILFAFVSSV... | animal organ regeneration B cell differentiation cellular response to cytokine stimulus cellular response to glucocorticoid stimulus common myeloid progenitor cell proliferation cytokine-mediated signaling pathway dendritic cell differentiation hemopoiesis leukocyte homeostasis lymphocyte proliferation myeloid progenit... |
activin receptor signaling pathway cellular response to growth factor stimulus extrinsic apoptotic signaling pathway G1/S transition of mitotic cell cycle hair follicle development in utero embryonic development negative regulation of cell growth negative regulation of gene expression nervous system development nodal s... | activin receptor complex; cell surface; cytosol; plasma membrane; receptor complex | activin binding activin receptor activity activin receptor activity, type I ATP binding I-SMAD binding inhibin binding metal ion binding protein serine/threonine kinase activity SMAD binding transmembrane receptor protein serine/threonine kinase activity ubiquitin protein ligase binding | Homo sapiens | 3D-structure Alternative splicing ATP-binding Cell membrane Glycoprotein Kinase Magnesium Manganese Membrane Metal-binding Nucleotide-binding Phosphoprotein Receptor Reference proteome Serine/threonine-protein kinase Signal Transferase Transmembrane Transmembrane helix Ubl conjugation | MAESAGASSF | MAESAGASSFFPLVVLLLAGSGGSGPRGVQALLCACTSCLQANYTCETDGACMVSIFNLDGMEHHVRTCIPKVELVPAGKPFYCLSSEDLRNTHCCYTDYCNRIDLRVPSGHLKEPEHPSMWGPVELVGIIAGPVFLLFLIIIIVFLVINYHQRVYHNRQRLDMEDPSCEMCLSKDKTLQDLVYDLSTSGSGSGLPLFVQRTVARTIVLQEIIGKGRFGEVWRGRWRGGDVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTIEGMIKLALSAASGLAHLHM... | activin receptor signaling pathway cellular response to growth factor stimulus extrinsic apoptotic signaling pathway G1/S transition of mitotic cell cycle hair follicle development in utero embryonic development negative regulation of cell growth negative regulation of gene expression nervous system development nodal s... |
cellular response to fibroblast growth factor stimulus cellular response to interleukin-1 cellular response to lipopolysaccharide cellular response to tumor necrosis factor embryonic digestive tract development immune response induction of positive chemotaxis inflammatory response intracellular signal transduction nega... | extracellular space | chemokine activity heparin binding interleukin-8 receptor binding | Ovis aries | Chemotaxis Citrullination Cytokine Disulfide bond Inflammatory response Reference proteome Secreted Signal | MTSKLAVALL | MTSKLAVALLAAFLLSAALCEAAVLSRMSTELRCQCIKTHSTPFHPKFIKELRVIESGPHCENSEIIVKLTNGKEVCLDPKEKWVQKVVQAFLKRAEKQDP | cellular response to fibroblast growth factor stimulus cellular response to interleukin-1 cellular response to lipopolysaccharide cellular response to tumor necrosis factor embryonic digestive tract development immune response induction of positive chemotaxis inflammatory response intracellular signal transduction nega... |
regulation of DNA-templated transcription rRNA base methylation | cytosol | RNA binding rRNA (cytosine-C5-)-methyltransferase activity | Escherichia coli | 3D-structure Cytoplasm Direct protein sequencing Methyltransferase Reference proteome RNA-binding rRNA processing S-adenosyl-L-methionine Transferase | MKKQRNLRSM | MKKQRNLRSMAAQAVEQVVEQGQSLSNILPPLQQKVSDKDKALLQELCFGVLRTLSQLDWLINKLMARPMTGKQRTVHYLIMVGLYQLLYTRIPPHAALAETVEGAIAIKRPQLKGLINGVLRQFQRQQEELLAEFNASDARYLHPSWLLKRLQKAYPEQWQSIVEANNQRPPMWLRINRTHHSRDSWLALLDEAGMKGFPHADYPDAVRLETPAPVHALPGFEDGWVTVQDASAQGCMTWLAPQNGEHILDLCAAPGGKTTHILEVAPEAQVVAVDIDEQRLSRVYDNLKRLGMKATVKQGDGRYPSQWCGEQQFDRIL... | regulation of DNA-templated transcription rRNA base methylation cytosol RNA binding rRNA (cytosine-C5-)-methyltransferase activity Escherichia coli 3D-structure Cytoplasm Direct protein sequencing Methyltransferase Reference proteome RNA-binding rRNA processing S-adenosyl-L-methionine Transferase MKKQRNLRSM MKKQRNLRSMA... |
monoatomic cation transmembrane transport potassium ion transmembrane transport potassium ion transport | plasma membrane; potassium ion-transporting ATPase complex; potassium:proton antiporter complex | P-type potassium transmembrane transporter activity | Escherichia coli | 3D-structure Cell inner membrane Cell membrane Ion transport Membrane Potassium Potassium transport Reference proteome Transmembrane Transmembrane helix Transport | MSAGVITGVL | MSAGVITGVLLVFLLLGYLVYALINAEAF | monoatomic cation transmembrane transport potassium ion transmembrane transport potassium ion transport plasma membrane; potassium ion-transporting ATPase complex; potassium:proton antiporter complex P-type potassium transmembrane transporter activity Escherichia coli 3D-structure Cell inner membrane Cell membrane Ion ... |
immune response necroptotic signaling pathway positive regulation of NF-kappaB transcription factor activity regulation of biological quality regulation of developmental process regulation of multicellular organismal process regulation of secretion vascular endothelial growth factor production | extracellular space; plasma membrane | cytokine activity tumor necrosis factor receptor binding | Peromyscus leucopus | Cell membrane Cytokine Disulfide bond Glycoprotein Lipoprotein Membrane Myristate Phosphoprotein Secreted Signal-anchor Transmembrane Transmembrane helix | MSTESMIRDV | MSTESMIRDVELAEEALPKKAWGPQNSSRCLCLSLFSFLLVAGATTLFCLLNFGVIGPQREEKFPNNLPIIGSMAQTLTLRSSSQNSSDKPVAHVVANHQVDEQLEWLSRGANALLANGMDLKDNQLVIPADGLYLVYSQVLFKGQGCSSYVLLTHTVSRFAVSYEDKVNLLSAIKSPCPKETPEGSELKPWYEPIYLGGVFQLEKGDRLSAEVNLPKYLDFAESGQVYFGVIAL | immune response necroptotic signaling pathway positive regulation of NF-kappaB transcription factor activity regulation of biological quality regulation of developmental process regulation of multicellular organismal process regulation of secretion vascular endothelial growth factor production extracellular space; plas... |
apoptotic process cellular response to mechanical stimulus hematopoietic or lymphoid organ development immune response myeloid dendritic cell differentiation positive regulation of canonical NF-kappaB signal transduction positive regulation of extrinsic apoptotic signaling pathway positive regulation of JNK cascade sig... | Golgi apparatus; plasma membrane | identical protein binding ubiquitin protein ligase binding | Homo sapiens | 3D-structure Alternative splicing Apoptosis Disulfide bond Glycoprotein Host-virus interaction Membrane Phosphoprotein Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix | MLLPWATSAP | MLLPWATSAPGLAWGPLVLGLFGLLAASQPQAVPPYASENQTCRDQEKEYYEPQHRICCSRCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGLEEIAPCTSKRKTQCRCQPGMFCAAWALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQNTSSPSARCQPHTRCENQGLVEAAPGTAQSDTTCKNPLEPLPPEMSGTMLMLAVLLPLAFFLLLATVFSCIWKSHPSLCRKLGSLLKRRPQGEGPNPVAGSWEPPKAHPYFPDLVQPLLPISGDVSPVSTGLPAAPVLEAGVPQ... | apoptotic process cellular response to mechanical stimulus hematopoietic or lymphoid organ development immune response myeloid dendritic cell differentiation positive regulation of canonical NF-kappaB signal transduction positive regulation of extrinsic apoptotic signaling pathway positive regulation of JNK cascade sig... |
extracellular matrix organization morphogenesis of an epithelium prostate gland morphogenesis regulation of epithelial cell proliferation | cornified envelope; cytoplasm; extracellular space; sarcoplasm | serine-type endopeptidase inhibitor activity | Homo sapiens | 3D-structure Alternative splicing Direct protein sequencing Glycoprotein Reference proteome Secreted | MDALQLANSA | MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHFENVKDVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESETKECPFRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDESTGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSEDTSDFSGMSETKGVALSNVIH... | extracellular matrix organization morphogenesis of an epithelium prostate gland morphogenesis regulation of epithelial cell proliferation cornified envelope; cytoplasm; extracellular space; sarcoplasm serine-type endopeptidase inhibitor activity Homo sapiens 3D-structure Alternative splicing Direct protein sequencing G... |
maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II transcription by RNA polymerase II transcription initiation at RNA polymerase II promoter transcription-coupled nucleotide-excision repair | nucleolus; nucleoplasm; nucleus; RNA polymerase II, core complex | DNA-directed 5'-3' RNA polymerase activity nucleic acid binding zinc ion binding | Homo sapiens | 3D-structure Acetylation DNA-directed RNA polymerase Metal-binding Nucleus Reference proteome Transcription Zinc Zinc-finger | MEPDGTYEPG | MEPDGTYEPGFVGIRFCQECNNMLYPKEDKENRILLYACRNCDYQQEADNSCIYVNKITHEVDELTQIIADVSQDPTLPRTEDHPCQKCGHKEAVFFQSHSARAEDAMRLYYVCTAPHCGHRWTE | maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II transcription by RNA polymerase II transcription initiation at RNA polymerase II promoter transcription-coupled nucleotide-excision repair nucleolus; nucleoplasm; nucleus; RNA polymerase II, core complex DNA-directed 5'-3' RNA ... |
cellular response to cobalt ion cellular response to dexamethasone stimulus cellular response to glucose stimulus cellular response to retinoic acid epithelial cell proliferation involved in prostate gland development kidney development negative regulation of angiogenesis negative regulation of endothelial cell migrati... | axon hillock; basement membrane; collagen-containing extracellular matrix; extracellular exosome; extracellular region; extracellular space; melanosome; perinuclear region of cytoplasm | serine-type endopeptidase inhibitor activity | Homo sapiens | 3D-structure Direct protein sequencing Dwarfism Glycoprotein Osteogenesis imperfecta Phosphoprotein Pyrrolidone carboxylic acid Reference proteome Secreted Signal | MQALVLLLCI | MQALVLLLCIGALLGHSSCQNPASPPEEGSPDPDSTGALVEEEDPFFKVPVNKLAAAVSNFGYDLYRVRSSTSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPDIHGTYKELLDTVTAPQKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLTGNPRLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHDIDRELKTVQAVLTVPKLKLS... | cellular response to cobalt ion cellular response to dexamethasone stimulus cellular response to glucose stimulus cellular response to retinoic acid epithelial cell proliferation involved in prostate gland development kidney development negative regulation of angiogenesis negative regulation of endothelial cell migrati... |
2-oxoglutarate metabolic process generation of precursor metabolites and energy histone succinylation L-lysine catabolic process to acetyl-CoA via saccharopine succinyl-CoA metabolic process tricarboxylic acid cycle | cytosol; membrane; mitochondrial matrix; mitochondrion; nucleoplasm; nucleus; oxoglutarate dehydrogenase complex | acyltransferase activity dihydrolipoyllysine-residue succinyltransferase activity | Homo sapiens | 3D-structure Acetylation Acyltransferase Alternative splicing Direct protein sequencing Disease variant Lipoyl Mitochondrion Nucleus Phosphoprotein Reference proteome Transferase Transit peptide Tricarboxylic acid cycle | MLSRSRCVSR | MLSRSRCVSRAFSRSLSAFQKGNCPLGRRSLPGVSLCQGPGYPNSRKVVINNSVFSVRFFRTTAVCKDDLVTVKTPAFAESVTEGDVRWEKAVGDTVAEDEVVCEIETDKTSVQVPSPANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSPSQPPSGKPVSAVKPTVAPPLAEPGAGKGLRSEHREKMNRMRQRIAQRLKEAQNTCAMLTTFNEIDMSNIQEMRARHKEAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDTTKEVVYRDYIDISVA... | 2-oxoglutarate metabolic process generation of precursor metabolites and energy histone succinylation L-lysine catabolic process to acetyl-CoA via saccharopine succinyl-CoA metabolic process tricarboxylic acid cycle cytosol; membrane; mitochondrial matrix; mitochondrion; nucleoplasm; nucleus; oxoglutarate dehydrogenase... |
purine nucleobase metabolic process purine nucleotide metabolic process response to cold | cytosol; GMP reductase complex | GMP reductase activity metal ion binding | Homo sapiens | 3D-structure Metal-binding NADP Oxidoreductase Potassium Purine metabolism Reference proteome | MPRIDADLKL | MPRIDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAVMSQHSMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECAGEVFERNGRKLKLFYGMSSDTAMNKHAGGVAEYRASEGKTVEVPYKGDVENTILDILGGLRSTCTYVG... | purine nucleobase metabolic process purine nucleotide metabolic process response to cold cytosol; GMP reductase complex GMP reductase activity metal ion binding Homo sapiens 3D-structure Metal-binding NADP Oxidoreductase Potassium Purine metabolism Reference proteome MPRIDADLKL MPRIDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNS... |
succinyl-CoA metabolic process tricarboxylic acid cycle | membrane; mitochondrion; succinate-CoA ligase complex (ADP-forming) | nucleotide binding succinate-CoA ligase (ADP-forming) activity succinate-CoA ligase (GDP-forming) activity | Dictyostelium discoideum | Direct protein sequencing Ligase Mitochondrion Nucleotide-binding Phosphoprotein Reference proteome Transit peptide Tricarboxylic acid cycle | MISAGMIARN | MISAGMIARNFGKRFFSTKPSVLINKHTKVICQGFTGNQGTFHSKQAIEYGTNMVGGVSPGKGGQKHLDLPVFNTVKEAKEATGANATVIYVPPPHAAAAIKEAIDAEMELVVCITEGIPQQDMVKVKYLLNKQNKTRLIGPNCPGIIKPGECKIGIMPGHIHKPGKIGIVSRSGTLTYEAVAQTTAVGLGQSTCIGIGGDPFNGTNFIDCLKMFTQDPQTEGIILIGEIGGEAEEEAAQWLIDNPTDKPVVSFIAGLSAPPGRRMGHAGAIISGGKGDANSKIEALKAAGVTVTFSPAKLGETILQKMNEKKNK | succinyl-CoA metabolic process tricarboxylic acid cycle membrane; mitochondrion; succinate-CoA ligase complex (ADP-forming) nucleotide binding succinate-CoA ligase (ADP-forming) activity succinate-CoA ligase (GDP-forming) activity Dictyostelium discoideum Direct protein sequencing Ligase Mitochondrion Nucleotide-bindin... |
arachidonic acid metabolic process lipoxygenase pathway negative regulation of ferroptosis response to oxidative stress spermatogenesis | cytosol; mitochondrion; nucleus | glutathione peroxidase activity phospholipid-hydroperoxide glutathione peroxidase activity | Sus scrofa | Alternative initiation Cytoplasm Developmental protein Direct protein sequencing Lipid metabolism Mitochondrion Oxidoreductase Peroxidase Phosphoprotein Reference proteome Selenocysteine Transit peptide | MSFSRLFRLL | MSFSRLFRLLKPTLLCGTLAVPGLAGTMCASRDDWRCARSMHEFSAKDIDGHMVNLDKYRGYVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRILAFPCNQFGRQEPGSDAEIKEFAAGYNVKFDMFSKICVNGDDAHPLWKWMKVQPKGRGMLGNAIKWNFTKFLIDKNGCVVKRYGPMEEPQVIEKDLPCYL | arachidonic acid metabolic process lipoxygenase pathway negative regulation of ferroptosis response to oxidative stress spermatogenesis cytosol; mitochondrion; nucleus glutathione peroxidase activity phospholipid-hydroperoxide glutathione peroxidase activity Sus scrofa Alternative initiation Cytoplasm Developmental pro... |
arachidonic acid metabolic process chromatin organization lipoxygenase pathway long-chain fatty acid biosynthetic process negative regulation of ferroptosis phospholipid metabolic process protein polymerization response to estradiol response to oxidative stress spermatogenesis | cytosol; extracellular exosome; mitochondrion; nuclear envelope; nucleus; protein-containing complex | glutathione peroxidase activity identical protein binding phospholipid-hydroperoxide glutathione peroxidase activity selenium binding | Homo sapiens | 3D-structure Alternative initiation Cytoplasm Developmental protein Dwarfism Lipid metabolism Mitochondrion Oxidoreductase Peroxidase Phosphoprotein Reference proteome Selenocysteine Transit peptide | MSLGRLCRLL | MSLGRLCRLLKPALLCGALAAPGLAGTMCASRDDWRCARSMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRILAFPCNQFGKQEPGSNEEIKEFAAGYNVKFDMFSKICVNGDDAHPLWKWMKIQPKGKGILGNAIKWNFTKFLIDKNGCVVKRYGPMEEPLVIEKDLPHYF | arachidonic acid metabolic process chromatin organization lipoxygenase pathway long-chain fatty acid biosynthetic process negative regulation of ferroptosis phospholipid metabolic process protein polymerization response to estradiol response to oxidative stress spermatogenesis cytosol; extracellular exosome; mitochondr... |
arachidonic acid metabolic process chromatin organization lipoxygenase pathway negative regulation of ferroptosis protein polymerization response to estradiol response to oxidative stress spermatogenesis | cytosol; mitochondrion; nuclear envelope; nucleolus; nucleus; protein-containing complex | glutathione peroxidase activity identical protein binding phospholipid-hydroperoxide glutathione peroxidase activity selenium binding | Rattus norvegicus | Alternative initiation Alternative splicing Cytoplasm Developmental protein Lipid metabolism Mitochondrion Nucleus Oxidoreductase Peroxidase Phosphoprotein Reference proteome Selenocysteine Transit peptide | MSWGRLSRLL | MSWGRLSRLLKPALLCGALAVPGLAGTMCASRDDWRCARSMHEFAAKDIDGHMVCLDKYRGCVCIVTNVASQUGKTDVNYTQLVDLHARYAECGLRILAFPCNQFGRQEPGSNQEIKEFAAGYNVRFDMYSKICVNGDDAHPLWKWMKVQPKGRGMLGNAIKWNFTKFLIDKNGCVVKRYGPMEEPQVIEKDLPCYL | arachidonic acid metabolic process chromatin organization lipoxygenase pathway negative regulation of ferroptosis protein polymerization response to estradiol response to oxidative stress spermatogenesis cytosol; mitochondrion; nuclear envelope; nucleolus; nucleus; protein-containing complex glutathione peroxidase acti... |
adenine metabolic process adenine salvage AMP salvage cellular response to insulin stimulus GMP salvage grooming behavior IMP salvage lactation purine ribonucleoside salvage | cytoplasm; cytosol | adenine binding adenine phosphoribosyltransferase activity AMP binding | Rattus norvegicus | Acetylation Cytoplasm Direct protein sequencing Glycosyltransferase Phosphoprotein Purine salvage Reference proteome Transferase | MSESELQLVA | MSESELQLVARRIRSFPDFPIPGVLFRDISPLLKDPDSFRASIRLLAGHLKSTHGGKIDYIAGLDSRGFLFGPSLAQELGVGCVLIRKRGKLPGPTVSASYSLEYGKAELEIQKDALEPGQKVVIVDDLLATGGTMCAACELLSQLRAEVVECVSLVELTSLKGREKLGPVPFFSLLQYE | adenine metabolic process adenine salvage AMP salvage cellular response to insulin stimulus GMP salvage grooming behavior IMP salvage lactation purine ribonucleoside salvage cytoplasm; cytosol adenine binding adenine phosphoribosyltransferase activity AMP binding Rattus norvegicus Acetylation Cytoplasm Direct protein s... |
exocytosis neuromuscular synaptic transmission neurotransmitter secretion regulation of short-term neuronal synaptic plasticity synaptic vesicle docking synaptic vesicle fusion to presynaptic active zone membrane synaptic vesicle priming synaptic vesicle transport vesicle fusion vesicle-mediated transport | cytoplasm; membrane; plasma membrane; SNARE complex; terminal bouton | SNAP receptor activity SNARE binding syntaxin binding | Drosophila melanogaster | Alternative splicing Coiled coil Reference proteome Repeat Synapse Synaptosome | MPADPSEEVA | MPADPSEEVAPQVPKTELEELQINAQGVADESLESTRRMLALCEESKEAGIRTLVALDDQGEQLDRIEEGMDQINADMREAEKNLSGMEKCCGICVLPCNKSQSFKEDDGTWKGNDDGKVVNNQPQRVMDDRNGMMAQAGYIGRITNDAREDEMEENMGQVNTMIGNLRNMALDMGSELENQNRQIDRINRKGESNEARIAVANQRAHQLLK | exocytosis neuromuscular synaptic transmission neurotransmitter secretion regulation of short-term neuronal synaptic plasticity synaptic vesicle docking synaptic vesicle fusion to presynaptic active zone membrane synaptic vesicle priming synaptic vesicle transport vesicle fusion vesicle-mediated transport cytoplasm; me... |
response to antibiotic rRNA base methylation tRNA methylation | cytosol | 4 iron, 4 sulfur cluster binding metal ion binding rRNA (adenine(2503)-C2-)-methyltransferase activity rRNA binding tRNA (adenine(37)-C2)-methyltransferase activity tRNA binding | Escherichia coli | 3D-structure 4Fe-4S Antibiotic resistance Cytoplasm Disulfide bond Iron Iron-sulfur Metal-binding Methyltransferase Reference proteome rRNA processing S-adenosyl-L-methionine Transferase tRNA processing | MSEQLVTPEN | MSEQLVTPENVTTKDGKINLLDLNRQQMREFFKDLGEKPFRADQVMKWMYHYCCDNFDEMTDINKVLRGKLKEVAEIRAPEVVEEQRSSDGTIKWAIAVGDQRVETVYIPEDDRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIVGAAKVTGQRPITNVVMMGMGEPLLNLNNVVPAMEIMLDDFGFGLSKRRVTLSTSGVVPALDKLGDMIDVALAISLHAPNDEIRDEIVPINKKYNIETFLAAVRRYLEKSNANQGRVTIEYVMLDHVNDGTEHAHQLAELLKDTPCKINLIPWNPFPGAPYG... | response to antibiotic rRNA base methylation tRNA methylation cytosol 4 iron, 4 sulfur cluster binding metal ion binding rRNA (adenine(2503)-C2-)-methyltransferase activity rRNA binding tRNA (adenine(37)-C2)-methyltransferase activity tRNA binding Escherichia coli 3D-structure 4Fe-4S Antibiotic resistance Cytoplasm Dis... |
complement activation cytolysis by host of symbiont cells negative regulation of protein binding | extracellular region; extracellular space; protein-containing complex | complement component C3b binding identical protein binding | Homo sapiens | 3D-structure Alternative splicing Direct protein sequencing Disulfide bond Glycoprotein Reference proteome Repeat Secreted Signal Sushi | MWLLVSVILI | MWLLVSVILISRISSVGGEAMFCDFPKINHGILYDEEKYKPFSQVPTGEVFYYSCEYNFVSPSKSFWTRITCAEEGWSPTPKCLRLCFFPFVENGHSESSGQTHLEGDTVQIICNTGYRLQNNENNISCVERGWSTPPKCRSTISAEKCGPPPPIDNGDITSFLLSVYAPGSSVEYQCQNLYQLEGNNQITCRNGQWSEPPKCLDPCVISQEIMEKYNIKLKWTNQQKLYSRTGDIVEFVCKSGYHPTKSHSFRAMCQNGKLVYPSCEEK | complement activation cytolysis by host of symbiont cells negative regulation of protein binding extracellular region; extracellular space; protein-containing complex complement component C3b binding identical protein binding Homo sapiens 3D-structure Alternative splicing Direct protein sequencing Disulfide bond Glycop... |
N-terminal protein myristoylation negative regulation of canonical NF-kappaB signal transduction negative regulation of defense response to virus negative regulation of interferon-beta production negative regulation of non-canonical NF-kappaB signal transduction positive regulation of canonical Wnt signaling pathway pr... | cytosol; membrane; nucleolus; nucleus | magnesium ion binding manganese ion binding myosin phosphatase activity protein serine/threonine phosphatase activity | Mus musculus | Alternative splicing Cytoplasm Hydrolase Isopeptide bond Lipoprotein Magnesium Manganese Membrane Metal-binding Myristate Phosphoprotein Protein phosphatase Reference proteome Ubl conjugation | MGAFLDKPKT | MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLDNWSFFAVYDGHAGSRVANYCSTHLLEHITTNEDFRAADKSGSALEPSVESVKTGIRTGFLKIDEYMRNFSDLRNGMDRSGSTAVGVMVSPTHMYFINCGDSRAVLCRNGQVCFSTQDHKPCNPVEKERIQNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEIVRAEEDEFVVLACDGIWDVMSNEELCEFVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSVVLVCFSNAPKVSEEAVKRDSELDKHLESRV... | N-terminal protein myristoylation negative regulation of canonical NF-kappaB signal transduction negative regulation of defense response to virus negative regulation of interferon-beta production negative regulation of non-canonical NF-kappaB signal transduction positive regulation of canonical Wnt signaling pathway pr... |
lipid A biosynthetic process | cell outer membrane | O-palmitoyltransferase activity | Escherichia coli | 3D-structure Acyltransferase Cell outer membrane Direct protein sequencing Membrane Reference proteome Signal Transferase | MNVSKYVAIF | MNVSKYVAIFSFVFIQLISVGKVFANADEWMTTFRENIAQTWQQPEHYDLYIPAITWHARFAYDKEKTDRYNERPWGGGFGLSRWDEKGNWHGLYAMAFKDSWNKWEPIAGYGWESTWRPLADENFHLGLGFTAGVTARDNWNYIPLPVLLPLASVGYGPVTFQMTYIPGTYNNGNVYFAWMRFQF | lipid A biosynthetic process cell outer membrane O-palmitoyltransferase activity Escherichia coli 3D-structure Acyltransferase Cell outer membrane Direct protein sequencing Membrane Reference proteome Signal Transferase MNVSKYVAIF MNVSKYVAIFSFVFIQLISVGKVFANADEWMTTFRENIAQTWQQPEHYDLYIPAITWHARFAYDKEKTDRYNERPWGGGFGLSRWDEKG... |
cellular detoxification of fluoride fluoride transmembrane transport | plasma membrane | fluoride channel activity fluoride transmembrane transporter activity metal ion binding | Escherichia coli | Cell inner membrane Cell membrane Ion channel Ion transport Membrane Metal-binding Reference proteome Sodium Transmembrane Transmembrane helix Transport | MLQLLLAVFI | MLQLLLAVFIGGGTGSVARWLLSMRFNPLHQAIPLGTLTANLIGAFIIGIGFAWFSRMTNIDPVWKVLITTGFCGGLTTFSTFSAEVVFLLQEGRFGWALLNVFVNLLGSFAMTALAFWLFSASTAH | cellular detoxification of fluoride fluoride transmembrane transport plasma membrane fluoride channel activity fluoride transmembrane transporter activity metal ion binding Escherichia coli Cell inner membrane Cell membrane Ion channel Ion transport Membrane Metal-binding Reference proteome Sodium Transmembrane Transme... |
carbohydrate metabolic process galactose catabolic process glucose 1-phosphate metabolic process glucose 6-phosphate metabolic process glucose metabolic process glycogen biosynthetic process intracellular calcium ion homeostasis intracellular monoatomic cation homeostasis trehalose biosynthetic process UDP-glucose meta... | cytoplasm; cytosol | magnesium ion binding phosphoglucomutase activity | Saccharomyces cerevisiae | Acetylation Carbohydrate metabolism Cytoplasm Direct protein sequencing Glucose metabolism Glycoprotein Isomerase Magnesium Metal-binding Phosphoprotein Reference proteome | MSFQIETVPT | MSFQIETVPTKPYEDQKPGTSGLRKKTKVFKDEPNYTENFIQSIMEAIPEGSKGATLVVGGDGRYYNDVILHKIAAIGAANGIKKLVIGQHGLLSTPAASHIMRTYEEKCTGGIILTASHNPGGPENDMGIKYNLSNGGPAPESVTNAIWEISKKLTSYKIIKDFPELDLGTIGKNKKYGPLLVDIIDITKDYVNFLKEIFDFDLIKKFIDNQRSTKNWKLLFDSMNGVTGPYGKAIFVDEFGLPADEVLQNWHPSPDFGGMHPDPNLTYASSLVKRVDREKIEFGAASDGDGDRNMIYGYGPSFVSPGDSVAIIAEYAA... | carbohydrate metabolic process galactose catabolic process glucose 1-phosphate metabolic process glucose 6-phosphate metabolic process glucose metabolic process glycogen biosynthetic process intracellular calcium ion homeostasis intracellular monoatomic cation homeostasis trehalose biosynthetic process UDP-glucose meta... |
cellular stress response to acidic pH chloride transmembrane transport proton transmembrane transport | plasma membrane | chloride:proton antiporter activity identical protein binding voltage-gated chloride channel activity | Escherichia coli | 3D-structure Antiport Cell inner membrane Cell membrane Chloride Ion transport Membrane Reference proteome Stress response Transmembrane Transmembrane helix Transport | MKTDTPSLET | MKTDTPSLETPQAARLRRRQLIRQLLERDKTPLAILFMAAVVGTLVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAPEAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGRMVLDIFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAVFIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGMQDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLI... | cellular stress response to acidic pH chloride transmembrane transport proton transmembrane transport plasma membrane chloride:proton antiporter activity identical protein binding voltage-gated chloride channel activity Escherichia coli 3D-structure Antiport Cell inner membrane Cell membrane Chloride Ion transport Memb... |
intracellular copper ion homeostasis intracellular iron ion homeostasis regulation of iron ion transport | chloride channel complex; early endosome; endoplasmic reticulum; endosome; endosome membrane; fungal-type vacuole; Golgi apparatus; Golgi medial cisterna; Golgi membrane; plasma membrane | voltage-gated chloride channel activity | Saccharomyces cerevisiae | CBS domain Chloride Chloride channel Endosome Golgi apparatus Ion channel Ion transport Membrane Reference proteome Repeat Transmembrane Transmembrane helix Transport | MPTTYVPINQ | MPTTYVPINQPIGDGEDVIDTNRFTNIPETQNFDQFVTIDKIAEENRPLSVDSDREFLNSKYRHYREVIWDRAKTFITLSSTAIVIGCIAGFLQVFTETLVNWKTGHCQRNWLLNKSFCCNGVVNEVTSTSNLLLKRQEFECEAQGLWIAWKGHVSPFIIFMLLSVLFALISTLLVKYVAPMATGSGISEIKVWVSGFEYNKEFLGFLTLVIKSVALPLAISSGLSVGKEGPSVHYATCCGYLLTKWLLRDTLTYSSQYEYITAASGAGVAVAFGAPIGGVLFGLEEIASANRFNSSTLWKSYYVALVAITTLKYIDPFR... | intracellular copper ion homeostasis intracellular iron ion homeostasis regulation of iron ion transport chloride channel complex; early endosome; endoplasmic reticulum; endosome; endosome membrane; fungal-type vacuole; Golgi apparatus; Golgi medial cisterna; Golgi membrane; plasma membrane voltage-gated chloride chann... |
cobalamin transport | cobalamin transport complex; membrane; outer membrane-bounded periplasmic space; periplasmic space | cobalamin binding | Escherichia coli | 3D-structure Direct protein sequencing Disulfide bond Periplasm Reference proteome Signal Transport | MAKSLFRALV | MAKSLFRALVALSFLAPLWLNAAPRVITLSPANTELAFAAGITPVGVSSYSDYPPQAQKIEQVSTWQGMNLERIVALKPDLVIAWRGGNAERQVDQLASLGIKVMWVDATSIEQIANALRQLAPWSPQPDKAEQAAQSLLDQYAQLKAQYADKPKKRVFLQFGINPPFTSGKESIQNQVLEVCGGENIFKDSRVPWPQVSREQVLARSPQAIVITGGPDQIPKIKQYWGEQLKIPVIPLTSDWFERASPRIILAAQQLCNALSQVD | cobalamin transport cobalamin transport complex; membrane; outer membrane-bounded periplasmic space; periplasmic space cobalamin binding Escherichia coli 3D-structure Direct protein sequencing Disulfide bond Periplasm Reference proteome Signal Transport MAKSLFRALV MAKSLFRALVALSFLAPLWLNAAPRVITLSPANTELAFAAGITPVGVSSYSDYPP... |
cellular organofluorine metabolic process demethylation electron transport chain fatty acid oxidation negative regulation of apoptotic process nitrate catabolic process nitric oxide catabolic process positive regulation of cholesterol biosynthetic process positive regulation of chondrocyte differentiation positive regu... | cytosol; endoplasmic reticulum membrane; intracellular membrane-bounded organelle | cytochrome-b5 reductase activity, acting on NAD(P)H electron transfer activity enzyme binding flavin adenine dinucleotide binding FMN binding hydrolase activity iron-cytochrome-c reductase activity NADP binding NADPH-hemoprotein reductase activity nitric oxide dioxygenase activity oxidoreductase activity | Mus musculus | Acetylation Endoplasmic reticulum FAD Flavoprotein FMN Membrane NADP Oxidoreductase Reference proteome Transmembrane Transmembrane helix | MGDSHEDTSA | MGDSHEDTSATVPEAVAEEVSLFSTTDIVLFSLIVGVLTYWFIFKKKKEEIPEFSKIQTTAPPVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEATGEESSIRQYELVVHEDMDTAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTTNRKLNQGTERHLMHLELDISDSKIRYESGDHV... | cellular organofluorine metabolic process demethylation electron transport chain fatty acid oxidation negative regulation of apoptotic process nitrate catabolic process nitric oxide catabolic process positive regulation of cholesterol biosynthetic process positive regulation of chondrocyte differentiation positive regu... |
luteinizing hormone secretion positive regulation of luteinizing hormone secretion regulation of hormone biosynthetic process regulation of testosterone secretion reproduction response to alkaloid response to serotonin | axon; extracellular region; extracellular space; perikaryon | gonadotropin hormone-releasing hormone activity gonadotropin-releasing hormone receptor binding | Gallus gallus | Amidation Cleavage on pair of basic residues Direct protein sequencing Hormone Pyrrolidone carboxylic acid Reference proteome Secreted Signal | MEKSRKILVG | MEKSRKILVGVLLFTASVAICLAQHWSYGLQPGGKRNAENLVESFQEIANEMESLGEGQKAECPGSYQHPRLSDLKETMASLIEGEARRKEI | luteinizing hormone secretion positive regulation of luteinizing hormone secretion regulation of hormone biosynthetic process regulation of testosterone secretion reproduction response to alkaloid response to serotonin axon; extracellular region; extracellular space; perikaryon gonadotropin hormone-releasing hormone ac... |
de novo' IMP biosynthetic process one-carbon metabolic process protein hexamerization purine nucleotide biosynthetic process | cytosol | formyltetrahydrofolate deformylase activity identical protein binding | Escherichia coli | Direct protein sequencing Hydrolase One-carbon metabolism Purine biosynthesis Reference proteome | MHSLQRKVLR | MHSLQRKVLRTICPDQKGLIARITNICYKHELNIVQNNEFVDHRTGRFFMRTELEGIFNDSTLLADLDSALPEGSVRELNPAGRRRIVILVTKEAHCLGDLLMKANYGGLDVEIAAVIGNHDTLRSLVERFDIPFELVSHEGLTRNEHDQKMADAIDAYQPDYVVLAKYMRVLTPEFVARFPNKIINIHHSFLPAFIGARPYHQAYERGVKIIGATAHYVNDNLDEGPIIMQDVIHVDHTYTAEDMMRAGRDVEKNVLSRALYKVLAQRVFVYGNRTIIL | de novo' IMP biosynthetic process one-carbon metabolic process protein hexamerization purine nucleotide biosynthetic process cytosol formyltetrahydrofolate deformylase activity identical protein binding Escherichia coli Direct protein sequencing Hydrolase One-carbon metabolism Purine biosynthesis Reference proteome MHS... |
androgen biosynthetic process male genitalia development steroid biosynthetic process testosterone biosynthetic process | endoplasmic reticulum; endoplasmic reticulum membrane; intracellular membrane-bounded organelle | 17-beta-hydroxysteroid dehydrogenase (NADP+) activity estradiol 17-beta-dehydrogenase activity testosterone 17-beta-dehydrogenase (NADP+) activity testosterone dehydrogenase activity | Homo sapiens | Alternative splicing Disease variant Endoplasmic reticulum Lipid biosynthesis Lipid metabolism NADP Oxidoreductase Pseudohermaphroditism Reference proteome Steroid biosynthesis | MGDVLEQFFI | MGDVLEQFFILTGLLVCLACLAKCVRFSRCVLLNYWKVLPKSFLRSMGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTKDDIYEHIKEKLAGLEIGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVKMTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQVLTPYAVSTAMTKYLNTNVITKTADEFVKESLNYVTIGGETCGCLAHEILAGFLSLIPAWAFYSGAFQRLLLTHYVAYLKLNTKVR | androgen biosynthetic process male genitalia development steroid biosynthetic process testosterone biosynthetic process endoplasmic reticulum; endoplasmic reticulum membrane; intracellular membrane-bounded organelle 17-beta-hydroxysteroid dehydrogenase (NADP+) activity estradiol 17-beta-dehydrogenase activity testoste... |
androgen metabolic process estrogen biosynthetic process in utero embryonic development placenta development response to retinoic acid steroid metabolic process | endoplasmic reticulum membrane; intracellular membrane-bounded organelle | 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity estradiol 17-beta-dehydrogenase activity testosterone dehydrogenase (NAD+) activity | Homo sapiens | Endoplasmic reticulum Lipid biosynthesis Lipid metabolism Membrane NAD Oxidoreductase Reference proteome Signal-anchor Steroid biosynthesis Transmembrane Transmembrane helix | MSTFFSDTAW | MSTFFSDTAWICLAVPTVLCGTVFCKYKKSSGQLWSWMVCLAGLCAVCLLILSPFWGLILFSVSCFLMYTYLSGQELLPVDQKAVLVTGGDCGLGHALCKYLDELGFTVFAGVLNENGPGAEELRRTCSPRLSVLQMDITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNIAGTSDKWEKLEKDILDHLPAEVQEDYGQDYILAQRNFLLLINSLASKDFSP... | androgen metabolic process estrogen biosynthetic process in utero embryonic development placenta development response to retinoic acid steroid metabolic process endoplasmic reticulum membrane; intracellular membrane-bounded organelle 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity estradiol 17-beta-d... |
cellular response to acidic pH cellular response to aldosterone cellular response to vasopressin intracellular sodium ion homeostasis multicellular organismal-level water homeostasis regulation of blood pressure sensory perception of salty taste sensory perception of sour taste sodium ion homeostasis sodium ion import ... | acrosomal vesicle; apical plasma membrane; ciliary membrane; cytoplasm; cytosol; external side of plasma membrane; extracellular exosome; motile cilium; plasma membrane; sodium channel complex; sperm principal piece | ligand-gated sodium channel activity WW domain binding | Homo sapiens | 3D-structure Alternative splicing Cell membrane Cell projection Cilium Cytoplasm Cytoplasmic vesicle Disease variant Flagellum Glycoprotein Ion channel Ion transport Membrane Reference proteome Sensory transduction Sodium Sodium channel Sodium transport Taste Transmembrane Transmembrane helix Transport Ubl conjugation | MEGNKLEEQD | MEGNKLEEQDSSPPQSTPGLMKGNKREEQGLGPEPAAPQQPTAEEEALIEFHRSYRELFEFFCNNTTIHGAIRLVCSQHNRMKTAFWAVLWLCTFGMMYWQFGLLFGEYFSYPVSLNINLNSDKLVFPAVTICTLNPYRYPEIKEELEELDRITEQTLFDLYKYSSFTTLVAGSRSRRDLRGTLPHPLQRLRVPPPPHGARRARSVASSLRDNNPQVDWKDWKIGFQLCNQNKSDCFYQTYSSGVDAVREWYRFHYINILSRLPETLPSLEEDTLGNFIFACRFNQVSCNQANYSHFHHPMYGNCYTFNDKNNSNLWMSS... | cellular response to acidic pH cellular response to aldosterone cellular response to vasopressin intracellular sodium ion homeostasis multicellular organismal-level water homeostasis regulation of blood pressure sensory perception of salty taste sensory perception of sour taste sodium ion homeostasis sodium ion import ... |
cellular response to acidic pH cellular response to aldosterone cellular response to vasopressin intracellular sodium ion homeostasis multicellular organismal-level water homeostasis regulation of blood pressure regulation of body fluid levels sensory perception of salty taste sensory perception of sour taste sodium io... | acrosomal vesicle; apical plasma membrane; ciliary membrane; cortical actin cytoskeleton; cytoplasm; cytosol; external side of plasma membrane; extracellular exosome; membrane; motile cilium; plasma membrane; sodium channel complex; sperm principal piece | actin binding ligand-gated sodium channel activity WW domain binding | Rattus norvegicus | Cell membrane Cell projection Cilium Cytoplasm Cytoplasmic vesicle Flagellum Glycoprotein Ion channel Ion transport Membrane Reference proteome Sensory transduction Sodium Sodium channel Sodium transport Taste Transmembrane Transmembrane helix Transport Ubl conjugation | MLDHTRAPEL | MLDHTRAPELNIDLDLHASNSPKGSMKGNQFKEQDPCPPQPMQGLGKGDKREEQGLGPEPSAPRQPTEEEEALIEFHRSYRELFQFFCNNTTIHGAIRLVCSKHNRMKTAFWAVLWLCTFGMMYWQFALLFEEYLSYPVSLNINLNSDKLVFPAVTVCTLNPYRYTEIKEELEELDRITEQTLFDLYKYNSSYTRQAGARRRSSRDLLGAFPHPLQRLRTPPPPYSGRTARSGSSSVRDNNPQVDRKDWKIGFQLCNQNKSDCFYQTYSSGVDAVREWYRFHYINILSRLSDTSPALEEEALGNFIFTCRFNQAPCNQAN... | cellular response to acidic pH cellular response to aldosterone cellular response to vasopressin intracellular sodium ion homeostasis multicellular organismal-level water homeostasis regulation of blood pressure regulation of body fluid levels sensory perception of salty taste sensory perception of sour taste sodium io... |
aldosterone metabolic process artery smooth muscle contraction cellular response to acidic pH cellular response to aldosterone cellular response to vasopressin epithelial fluid transport erythrocyte homeostasis gene expression intracellular sodium ion homeostasis leukocyte activation involved in inflammatory response m... | apical plasma membrane; cell surface; cytoplasmic vesicle membrane; external side of plasma membrane; extracellular exosome; membrane; plasma membrane; sodium channel complex | ligand-gated sodium channel activity WW domain binding | Rattus norvegicus | 3D-structure Cell membrane Cytoplasmic vesicle Glycoprotein Ion channel Ion transport Membrane Phosphoprotein Reference proteome Sensory transduction Sodium Sodium channel Sodium transport Taste Transmembrane Transmembrane helix Transport | MPVKKYLLKC | MPVKKYLLKCLHRLQKGPGYTYKELLVWYCNNTNTHGPKRIICEGPKKKAMWFLLTLLFACLVCWQWGVFIQTYLSWEVSVSLSMGFKTMNFPAVTVCNSSPFQYSKVKHLLKDLYKLMEAVLDKILAPKSSHTNTTSTLNFTIWNHTPLVLIDERNPDHPVVLNLFGDSHNSSNPAPGSTCNAQGCKVAMRLCSANGTVCTFRNFTSATQAVTEWYILQATNIFSQVLPQDLVGMGYAPDRIILACLFGTEPCSHRNFTPIFYPDYGNCYIFNWGMTEKALPSANPGTEFGLKLILDIGQEDYVPFLASTAGARLMLHE... | aldosterone metabolic process artery smooth muscle contraction cellular response to acidic pH cellular response to aldosterone cellular response to vasopressin epithelial fluid transport erythrocyte homeostasis gene expression intracellular sodium ion homeostasis leukocyte activation involved in inflammatory response m... |
cellular response to acidic pH cellular response to aldosterone cellular response to vasopressin intracellular sodium ion homeostasis multicellular organismal-level water homeostasis regulation of blood pressure response to hypoxia sensory perception of salty taste sensory perception of sour taste sodium ion homeostasi... | apical plasma membrane; cell surface; external side of plasma membrane; extracellular exosome; membrane; plasma membrane; sodium channel complex | ligand-gated sodium channel activity monoatomic ion channel activity WW domain binding | Rattus norvegicus | Cell membrane Glycoprotein Ion channel Ion transport Membrane Phosphoprotein Reference proteome Sensory transduction Sodium Sodium channel Sodium transport Taste Transmembrane Transmembrane helix Transport Ubl conjugation | MAPGEKIKAK | MAPGEKIKAKIKKNLPVRGPQAPTIKDLMHWYCMNTNTHGCRRIVVSRGRLRRLLWIAFTLTAVALIIWQCALLVFSFYTVSVSIKVHFQKLDFPAVTICNINPYKYSAVSDLLTDLDSETKQALLSLYGVKESRKRREAGSMPSTLEGTPPRFFKLIPLLVFNENEKGKARDFFTGRKRKISGKIIHKASNVMHVHESKKLVGFQLCSNDTSDCATYTFSSGINAIQEWYKLHYMNIMAQVPLEKKINMSYSAEELLVTCFFDGMSCDARNFTLFHHPMYGNCYTFNNKENATILSTSMGGSEYGLQVILYINEDEYNP... | cellular response to acidic pH cellular response to aldosterone cellular response to vasopressin intracellular sodium ion homeostasis multicellular organismal-level water homeostasis regulation of blood pressure response to hypoxia sensory perception of salty taste sensory perception of sour taste sodium ion homeostasi... |
protein secretion by the type II secretion system | plasma membrane; type II protein secretion system complex | ATP binding ATP hydrolysis activity metal ion binding protein-exporting ATPase activity | Vibrio cholerae serotype O1 | 3D-structure ATP-binding Cell inner membrane Cell membrane Membrane Metal-binding Nucleotide-binding Protein transport Reference proteome Translocase Transport Zinc | MTEMVISPAE | MTEMVISPAERQSIRRLPFSFANRFKLVLDWNEDFSQASIYYLAPLSMEALVETKRVVKHAFQLIELSQAEFESKLTQVYQRDSSEARQLMEDIGADSDDFFSLAEELPQNEDLLESEDDAPIIKLINAMLGEAIKEGASDIHIETFEKTLSIRFRVDGVLREVLAPSRKLSSLLVSRVKVMAKLDIAEKRVPQDGRISLRIGGRAVDVRVSTMPSSHGERVVMRLLDKNATRLDLHSLGMTAHNHDNFRRLIKRPHGIILVTGPTGSGKSTTLYAGLQELNSSERNILTVEDPIEFDIDGIGQTQVNPRVDMTFARGLR... | protein secretion by the type II secretion system plasma membrane; type II protein secretion system complex ATP binding ATP hydrolysis activity metal ion binding protein-exporting ATPase activity Vibrio cholerae serotype O1 3D-structure ATP-binding Cell inner membrane Cell membrane Membrane Metal-binding Nucleotide-bin... |
peptide catabolic process proteolysis | cytoplasm; cytosol | aminopeptidase activity identical protein binding manganese ion binding metalloaminopeptidase activity peptidase activity | Escherichia coli | 3D-structure Aminopeptidase Cytoplasm Hydrolase Manganese Metal-binding Protease Reference proteome | MTEAMKITLS | MTEAMKITLSTQPADARWGEKATYSINNDGITLHLNGADDLGLIQRAARKIDGLGIKHVQLSGEGWDADRCWAFWQGYKAPKGTRKVVWPDLDDAQRQELDNRLMIIDWVRDTINAPAEELGPSQLAQRAVDLISNVAGDRVTYRITKGEDLREQGYMGLHTVGRGSERSPVLLALDYNPTGDKEAPVYACLVGKGITFDSGGYSIKQTAFMDSMKSDMGGAATVTGALAFAITRGLNKRVKLFLCCADNLISGNAFKLGDIITYRNGKKVEVMNTDAEGRLVLADGLIDASAQKPEMIIDAATLTGAAKTALGNDYHAL... | peptide catabolic process proteolysis cytoplasm; cytosol aminopeptidase activity identical protein binding manganese ion binding metalloaminopeptidase activity peptidase activity Escherichia coli 3D-structure Aminopeptidase Cytoplasm Hydrolase Manganese Metal-binding Protease Reference proteome MTEAMKITLS MTEAMKITLSTQP... |
protein heterotrimerization SRP-dependent cotranslational protein targeting to membrane | chloroplast; chloroplast stroma; plasma membrane; protein-containing complex; signal recognition particle, endoplasmic reticulum targeting | 7S RNA binding ATP hydrolysis activity GTP binding GTPase activity protein domain specific binding | Arabidopsis thaliana | 3D-structure Chloroplast GTP-binding Hydrolase Nucleotide-binding Plastid Reference proteome Ribonucleoprotein RNA-binding Signal recognition particle Transit peptide | MEALQFSSVN | MEALQFSSVNRVPCTLSCTGNRRIKAAFSSAFTGGTINSASLSSSRNLSTREIWSWVKSKTVVGHGRYRRSQVRAEMFGQLTGGLEAAWSKLKGEEVLTKDNIAEPMRDIRRALLEADVSLPVVRRFVQSVSDQAVGMGVIRGVKPDQQLVKIVHDELVKLMGGEVSELQFAKSGPTVILLAGLQGVGKTTVCAKLACYLKKQGKSCMLIAGDVYRPAAIDQLVILGEQVGVPVYTAGTDVKPADIAKQGLKEAKKNNVDVVIMDTAGRLQIDKGMMDELKDVKKFLNPTEVLLVVDAMTGQEAAALVTTFNVEIGITGA... | protein heterotrimerization SRP-dependent cotranslational protein targeting to membrane chloroplast; chloroplast stroma; plasma membrane; protein-containing complex; signal recognition particle, endoplasmic reticulum targeting 7S RNA binding ATP hydrolysis activity GTP binding GTPase activity protein domain specific bi... |
cotranslational protein targeting to membrane protein targeting to ER SRP-dependent cotranslational protein targeting to membrane | cytoplasm; cytosol; extracellular region; ficolin-1-rich granule lumen; nucleus; secretory granule lumen; signal recognition particle, endoplasmic reticulum targeting | 7S RNA binding endoplasmic reticulum signal peptide binding RNA binding | Homo sapiens | 3D-structure Cytoplasm Direct protein sequencing Phosphoprotein Reference proteome Ribonucleoprotein RNA-binding Signal recognition particle | MVLLESEQFL | MVLLESEQFLTELTRLFQKCRTSGSVYITLKKYDGRTKPIPKKGTVEGFEPADNKCLLRATDGKKKISTVVSSKEVNKFQMAYSNLLRANMDGLKKRDKKNKTKKTKAAAAAAAAAPAAAATAPTTAATTAATAAQ | cotranslational protein targeting to membrane protein targeting to ER SRP-dependent cotranslational protein targeting to membrane cytoplasm; cytosol; extracellular region; ficolin-1-rich granule lumen; nucleus; secretory granule lumen; signal recognition particle, endoplasmic reticulum targeting 7S RNA binding endoplas... |
nucleoside phosphate metabolic process ribose phosphate metabolic process | cytosol | GDP-mannose hydrolase activity magnesium ion binding protein homodimerization activity | Escherichia coli | 3D-structure Hydrolase Magnesium Metal-binding Reference proteome | MTQQITLIKD | MTQQITLIKDKILSDNYFTLHNITYDLTRKDGEVIRHKREVYDRGNGATILLYNTKKKTVVLIRQFRVATWVNGNESGQLIESCAGLLDNDEPEVCIRKEAIEETGYEVGEVRKLFELYMSPGGVTELIHFFIAEYSDNQRANAGGGVEDEDIEVLELPFSQALEMIKTGEIRDGKTVLLLNYLQTSHLMD | nucleoside phosphate metabolic process ribose phosphate metabolic process cytosol GDP-mannose hydrolase activity magnesium ion binding protein homodimerization activity Escherichia coli 3D-structure Hydrolase Magnesium Metal-binding Reference proteome MTQQITLIKD MTQQITLIKDKILSDNYFTLHNITYDLTRKDGEVIRHKREVYDRGNGATILLYNTKK... |
acetylcholine catabolic process acetylcholine catabolic process in synaptic cleft acetylcholine metabolic process acetylcholine receptor signaling pathway cell adhesion choline metabolic process osteoblast development positive regulation of axonogenesis positive regulation of cold-induced thermogenesis positive regulat... | axon; basement membrane; cell surface; dendrite; endoplasmic reticulum lumen; extracellular region; extracellular space; Golgi apparatus; membrane; neuromuscular junction; neuronal cell body; nuclear envelope; perinuclear region of cytoplasm; plasma membrane; postsynaptic membrane; presynaptic membrane; side of membran... | acetylcholine binding acetylcholinesterase activity choline binding cholinesterase activity collagen binding hydrolase activity identical protein binding laminin binding protein homodimerization activity protein self-association serine hydrolase activity | Rattus norvegicus | Alternative splicing Cell membrane Disulfide bond Glycoprotein GPI-anchor Hydrolase Lipoprotein Membrane Neurotransmitter degradation Reference proteome Secreted Serine esterase Signal Synapse | MRPPWYPLHT | MRPPWYPLHTPSLASPLLFLLLSLLGGGARAEGREDPQLLVRVRGGQLRGIRLKAPGGPVSAFLGIPFAEPPVGSRRFMPPEPKRPWSGILDATTFQNVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLIWIYGGGFYSGASSLDVYDGRFLAQVEGTVLVSMNYRVGTFGFLALPGSREAPGNVGLLDQRLALQWVQENIAAFGGDPMSVTLFGESAGAASVGMHILSLPSRSLFHRAVLQSGTPNGPWATVSAGEARRRATLLARLVGCPPGGAGGNDTELISCLRTRPAQDLVDHEWHVL... | acetylcholine catabolic process acetylcholine catabolic process in synaptic cleft acetylcholine metabolic process acetylcholine receptor signaling pathway cell adhesion choline metabolic process osteoblast development positive regulation of axonogenesis positive regulation of cold-induced thermogenesis positive regulat... |
brain development glucose metabolic process lipid metabolic process lipid transport negative regulation of cytokine production involved in inflammatory response negative regulation of focal adhesion assembly negative regulation of lipoprotein lipid oxidation negative regulation of monocyte chemotactic protein-1 product... | cytosolic ribosome; dendrite; endoplasmic reticulum; extracellular space; neuronal cell body; perinuclear region of cytoplasm | cholesterol binding | Oryctolagus cuniculus | Disulfide bond Glycoprotein Lipid-binding Pyrrolidone carboxylic acid Reference proteome Secreted Signal Transport | MAPTLLLLLP | MAPTLLLLLPALAGLISVAQGQAFHLGRCPTPPVQENFDVHKYLGRWYEIEKIPVSFEKGNCIQANYSLMENGNIKVLNQELRPDGTVNQIEGQATQSNLTEPAKLGVKFFQLMPTAPYWVLATDYENYALVYSCTTIIWLFHMDHVWILGRNRYLPPETVTYLKDILTANNIDIEKMTVTDQVNCPEF | brain development glucose metabolic process lipid metabolic process lipid transport negative regulation of cytokine production involved in inflammatory response negative regulation of focal adhesion assembly negative regulation of lipoprotein lipid oxidation negative regulation of monocyte chemotactic protein-1 product... |
angiogenesis cell adhesion cell migration epithelial to mesenchymal transition regulation of transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway vasculogenesis | plasma membrane | glycosaminoglycan binding transforming growth factor beta receptor activity type I transforming growth factor beta receptor binding type II transforming growth factor beta receptor binding | Sus scrofa | Angiogenesis Cell adhesion Cell membrane Disulfide bond Glycoprotein Membrane Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix | MDRGVLPQAI | MDRGVLPQAIALLLAVCSFGPTAGLAEGVQCDLQPVDPKVTYTTSQVSEGCVAHVPNATVGVHILFLEFSKEVSTLELTVQMTNPNGARPQEVLLILSVNKNIHLTLQVPEIPLHLAYDSKLVFLQEAPKAVITELPPSTTKNQLFLWANTKGSIISAAELDNPQSILLRLDQAPTSPSRCTLEPRKDMGHTLEWKSHTQASVLGCHLEGVTGHKEAHILRVLPGSEAWPRTVTVEVELSCALRDPEAVLILQGPPYVSWLIDANHNVKAWTTGEYSFKIFPGSNIQGVNLPDTRQGLLEEARKLNASVIASFVELPLAS... | angiogenesis cell adhesion cell migration epithelial to mesenchymal transition regulation of transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway vasculogenesis plasma membrane glycosaminoglycan binding transforming growth factor beta receptor activity ty... |
phosphoenolpyruvate-dependent sugar phosphotransferase system phosphorylation response to organonitrogen compound | cytoplasm | kinase activity metal ion binding phosphoenolpyruvate-protein phosphotransferase activity | Escherichia coli | 3D-structure Cytoplasm Kinase Magnesium Metal-binding Phosphotransferase system Reference proteome Sugar transport Transferase Transport | MLTRLREIVE | MLTRLREIVEKVASAPRLNEALNILVTDICLAMDTEVCSVYLADHDRRCYYLMATRGLKKPRGRTVTLAFDEGIVGLVGRLAEPINLADAQKHPSFKYIPSVKEERFRAFLGVPIIQRRQLLGVLVVQQRELRQYDESEESFLVTLATQMAAILSQSQLTALFGQYRQTRIRALPAAPGVAIAEGWQDATLPLMEQVYQASTLDPALERERLTGALEEAANEFRRYSKRFAAGAQKETAAIFDLYSHLLSDTRLRRELFAEVDKGSVAEWAVKTVIEKFAEQFAALSDNYLKERAGDLRALGQRLLFHLDDANQGPNAWP... | phosphoenolpyruvate-dependent sugar phosphotransferase system phosphorylation response to organonitrogen compound cytoplasm kinase activity metal ion binding phosphoenolpyruvate-protein phosphotransferase activity Escherichia coli 3D-structure Cytoplasm Kinase Magnesium Metal-binding Phosphotransferase system Reference... |
galactitol metabolic process galactitol transmembrane transport phosphoenolpyruvate-dependent sugar phosphotransferase system | cytosol; transmembrane transporter complex | protein-N(PI)-phosphohistidine-sugar phosphotransferase activity protein-phosphocysteine-galactitol-phosphotransferase system transporter activity | Escherichia coli | Cytoplasm Direct protein sequencing Galactitol metabolism Phosphoprotein Phosphotransferase system Reference proteome Sugar transport Transferase Transport | MKRKIIVACG | MKRKIIVACGGAVATSTMAAEEIKELCQNHNIPVELIQCRVNEIETYMDGVHLICTTAKVDRSFGDIPLVHGMPFISGIGIEALQNKILTILQG | galactitol metabolic process galactitol transmembrane transport phosphoenolpyruvate-dependent sugar phosphotransferase system cytosol; transmembrane transporter complex protein-N(PI)-phosphohistidine-sugar phosphotransferase activity protein-phosphocysteine-galactitol-phosphotransferase system transporter activity Esch... |
exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) nonfunctional rRNA decay nuclear mRNA surveillance of mRNA 3'-... | chromatin; cytoplasmic exosome (RNase complex); exosome (RNase complex); nuclear exosome (RNase complex); nuclear exosome focus; nucleolus; nucleoplasm; nucleus | 3'-5'-RNA exonuclease activity endonuclease activity RNA binding RNA endonuclease activity RNA exonuclease activity RNA nuclease activity small GTPase binding | Schizosaccharomyces pombe | Cytoplasm Endonuclease Exonuclease Exosome Hydrolase Nuclease Nucleus Reference proteome RNA-binding rRNA processing | MSTVSGLKRP | MSTVSGLKRPQSSEKNHRDRVFVRATRGKVQKVVREQYLRNDIPCQSRACPLCRSKLPKDSRGNVLEPILSEKPMFLEKFGHHYLIPDSNIFYHCIDALEHPNNFFDVIILQTVFSEISSKSIPLYNRMKRLCQEKTKRFTPFSNEFFVDTFVERLDDESANDRNDRAIRNAASWFASHLASLGIKIVLLTDDRENARLAAEQGIQVSTLKDYVQYLPDSEILLDMVSAIADAIASKEQVESGTKNVYELHWSMSRLLACIKNGEVHKGLINISTYNYLEGSVVVPGYNKPVLVSGRENLNRAVQGDIVCIQILPQDQWK... | exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) nonfunctional rRNA decay nuclear mRNA surveillance of mRNA 3'-... |
ribosomal small subunit biogenesis | cytoplasm; plasma membrane | GDP binding GTP binding GTPase activity small ribosomal subunit rRNA binding | Streptococcus mutans serotype c | Cell membrane Cytoplasm GTP-binding Membrane Nucleotide-binding Reference proteome Ribosome biogenesis RNA-binding rRNA-binding | MSFKSGFVAI | MSFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKIMGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEKRGKGDNMIIERLKAAKVPVILVINKIDKVHPNQLLEQIDDFRNQMDFQEIVPISALQGNNVSHLVDLLVDHLEEGFQYFPADQITDHPERFLVSEMIREKVLLLTREEIPHSVAVVIDSMARDEETHKIHIRATIMVERDSQKGIIIGKKGAMLKKIGQMARRDIELMLGDKVYLETWVKVKKNWRDKKLDLADFGYNKKEY | ribosomal small subunit biogenesis cytoplasm; plasma membrane GDP binding GTP binding GTPase activity small ribosomal subunit rRNA binding Streptococcus mutans serotype c Cell membrane Cytoplasm GTP-binding Membrane Nucleotide-binding Reference proteome Ribosome biogenesis RNA-binding rRNA-binding MSFKSGFVAI MSFKSGFVAI... |
cellular response to xenobiotic stimulus | cell surface; external side of plasma membrane; protein-containing complex | calcium ion binding carbohydrate binding identical protein binding | Mus musculus | Disulfide bond Glycoprotein Lectin Membrane Phosphoprotein Reference proteome Signal-anchor Transmembrane Transmembrane helix | MDSENCSITE | MDSENCSITENSSSHLERGQKDHGTSIHFEKHHEGSIQVSIPWAVLIVVLITSLIIALIALNVGKYNCPGLYEKLESSDHHVATCKNEWISYKRTCYFFSTTTKSWALAQRSCSEDAATLAVIDSEKDMTFLKRYSGELEHWIGLKNEANQTWKWANGKEFNSWFNLTGSGRCVSVNHKNVTAVDCEANFHWVCSKPSR | cellular response to xenobiotic stimulus cell surface; external side of plasma membrane; protein-containing complex calcium ion binding carbohydrate binding identical protein binding Mus musculus Disulfide bond Glycoprotein Lectin Membrane Phosphoprotein Reference proteome Signal-anchor Transmembrane Transmembrane heli... |
chemical synaptic transmission neuromuscular junction development neurotransmitter secretion regulation of neurotransmitter secretion | cytoplasm; presynapse | calcium ion binding calcium sensitive guanylate cyclase activator activity | Drosophila melanogaster | Calcium Cytoplasm Lipoprotein Metal-binding Myristate Reference proteome Repeat RNA editing | MGKKSSKLKQ | MGKKSSKLKQDTIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPQGDPSKFASLVFRVFDENNDGSIEFEEFIRALSVTSKGNLDEKLQWAFRLYDVDNDGYITREEMYNIVDAIYQMVGQQPQSEDENTPQKRVDKIFDQMDKNHDGKLTLEEFREGSKADPRIVQALSLGGG | chemical synaptic transmission neuromuscular junction development neurotransmitter secretion regulation of neurotransmitter secretion cytoplasm; presynapse calcium ion binding calcium sensitive guanylate cyclase activator activity Drosophila melanogaster Calcium Cytoplasm Lipoprotein Metal-binding Myristate Reference p... |
folic acid biosynthetic process glutamine metabolic process para-aminobenzoic acid biosynthetic process tetrahydrofolate biosynthetic process tryptophan biosynthetic process | cytoplasm | 4-amino-4-deoxychorismate synthase activity | Saccharomyces cerevisiae | Cytoplasm Folate biosynthesis Glutamine amidotransferase Multifunctional enzyme Reference proteome Transferase | MLSDTIDTKQ | MLSDTIDTKQQQQQLHVLFIDSYDSFTYNVVRLIEQQTDISPGVNAVHVTTVHSDTFQSMDQLLPLLPLFDAIVVGPGPGNPNNGAQDMGIISELFENANGKLDEVPILGICLGFQAMCLAQGADVSELNTIKHGQVYEMHLNDAARACGLFSGYPDTFKSTRYHSLHVNAEGIDTLLPLCTTEDENGILLMSAQTKNKPWFGVQYHPESCCSELGGLLVSNFLKLSFINNVKTGRWEKKKLNGEFSDILSRLDRTIDRDPIYKVKEKYPKGEDTTYVKQFEVSEDPKLTFEICNIIREEKFVMSSSVISENTGEWSIIA... | folic acid biosynthetic process glutamine metabolic process para-aminobenzoic acid biosynthetic process tetrahydrofolate biosynthetic process tryptophan biosynthetic process cytoplasm 4-amino-4-deoxychorismate synthase activity Saccharomyces cerevisiae Cytoplasm Folate biosynthesis Glutamine amidotransferase Multifunc... |
cholesterol biosynthetic process farnesyl diphosphate metabolic process steroid biosynthetic process | endoplasmic reticulum; endoplasmic reticulum membrane; membrane | farnesyl-diphosphate farnesyltransferase activity metal ion binding squalene synthase activity | Homo sapiens | 3D-structure Alternative splicing Cholesterol biosynthesis Cholesterol metabolism Endoplasmic reticulum Lipid biosynthesis Lipid metabolism Magnesium Membrane Metal-binding Multifunctional enzyme NAD NADP Reference proteome Steroid biosynthesis Steroid metabolism Sterol biosynthesis Sterol metabolism Transferase Transm... | MEFVKCLGHP | MEFVKCLGHPEEFYNLVRFRIGGKRKVMPKMDQDSLSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQ... | cholesterol biosynthetic process farnesyl diphosphate metabolic process steroid biosynthetic process endoplasmic reticulum; endoplasmic reticulum membrane; membrane farnesyl-diphosphate farnesyltransferase activity metal ion binding squalene synthase activity Homo sapiens 3D-structure Alternative splicing Cholesterol b... |
carotenoid biosynthetic process | chromoplast stroma | farnesyltranstransferase activity geranylgeranyl-diphosphate geranylgeranyltransferase activity | Capsicum annuum | Carotenoid biosynthesis Chromoplast Isoprene biosynthesis Plastid Transferase Transit peptide | MSVALLWVVS | MSVALLWVVSPCDVSNGTGFLVSVREGNRIFDSSGRRNLACNERIKRGGGKQRWSFGSYLGGAQTGSGRKFSVRSAIVATPAGEMTMSSERMVYDVVLRQAALVKRQLRSTDELDVKKDIPIPGTLGLLSEAYDRCSEVCAEYAKTFYLGTMLMTPERRKAIWAIYVWCRRTDELVDGPNASHITPAALDRWEDRLEDVFSGRPFDMLDAALSDTVSKFPVDIQPFRDMIEGMRMDLRKSRYRNFDELYLYCYYVAGTVGLMSVPIMGIAPESKATTESVYNAALALGIANQLTNILRDVGEDARRGRVYLPQDELAQAG... | carotenoid biosynthetic process chromoplast stroma farnesyltranstransferase activity geranylgeranyl-diphosphate geranylgeranyltransferase activity Capsicum annuum Carotenoid biosynthesis Chromoplast Isoprene biosynthesis Plastid Transferase Transit peptide MSVALLWVVS MSVALLWVVSPCDVSNGTGFLVSVREGNRIFDSSGRRNLACNERIKRGGGKQ... |
axo-dendritic transport cell adhesion intracellular protein transport microtubule-based movement protein localization to synapse stress granule disassembly | axon; ciliary rootlet; cytoplasm; cytoplasmic vesicle; cytosol; growth cone; kinesin complex; membrane; membrane-bounded organelle; microtubule; neuron projection; neuronal cell body; vesicle | kinesin binding tubulin binding | Rattus norvegicus | Alternative splicing Calcium Cell adhesion Cell projection Coiled coil Cytoplasm Cytoplasmic vesicle Cytoskeleton Microtubule Motor protein Phosphoprotein Reference proteome Repeat TPR repeat | MHDNMSTMVY | MHDNMSTMVYMKEEKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSSMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDSDSSKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLC... | axo-dendritic transport cell adhesion intracellular protein transport microtubule-based movement protein localization to synapse stress granule disassembly axon; ciliary rootlet; cytoplasm; cytoplasmic vesicle; cytosol; growth cone; kinesin complex; membrane; membrane-bounded organelle; microtubule; neuron projection; ... |
cellular response to leukemia inhibitory factor GPI anchor biosynthetic process preassembly of GPI anchor in ER membrane | endoplasmic reticulum membrane; glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex; membrane | phosphatidylinositol N-acetylglucosaminyltransferase activity UDP-glycosyltransferase activity | Homo sapiens | Alternative splicing Disease variant Endoplasmic reticulum Epilepsy Glycoprotein Glycosyltransferase GPI-anchor biosynthesis Intellectual disability Lipid metabolism Membrane Phosphoprotein Reference proteome Transferase Transmembrane Transmembrane helix | MACRGGAGNG | MACRGGAGNGHRASATLSRVSPGSLYTCRTRTHNICMVSDFFYPNMGGVESHIYQLSQCLIERGHKVIIVTHAYGNRKGIRYLTSGLKVYYLPLKVMYNQSTATTLFHSLPLLRYIFVRERVTIIHSHSSFSAMAHDALFHAKTMGLQTVFTDHSLFGFADVSSVLTNKLLTVSLCDTNHIICVSYTSKENTVLRAALNPEIVSVIPNAVDPTDFTPDPFRRHDSITIVVVSRLVYRKGIDLLSGIIPELCQKYPDLNFIIGGEGPKRIILEEVRERYQLHDRVRLLGALEHKDVRNVLVQGHIFLNTSLTEAFCMAIVE... | cellular response to leukemia inhibitory factor GPI anchor biosynthetic process preassembly of GPI anchor in ER membrane endoplasmic reticulum membrane; glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex; membrane phosphatidylinositol N-acetylglucosaminyltransferase activity UDP-glycosyltran... |
folic acid metabolic process glycine biosynthetic process from serine L-serine catabolic process one-carbon metabolic process tetrahydrofolate interconversion tetrahydrofolate metabolic process | cytoplasm; mating projection tip; plasma membrane | glycine hydroxymethyltransferase activity pyridoxal phosphate binding serine binding zinc ion binding | Saccharomyces cerevisiae | Cytoplasm Direct protein sequencing Isopeptide bond One-carbon metabolism Phosphoprotein Pyridoxal phosphate Reference proteome Transferase Ubl conjugation | MPYTLSDAHH | MPYTLSDAHHKLITSHLVDTDPEVDSIIKDEIERQKHSIDLIASENFTSTSVFDALGTPLSNKYSEGYPGARYYGGNEHIDRMEILCQQRALKAFHVTPDKWGVNVQTLSGSPANLQVYQAIMKPHERLMGLYLPDGGHLSHGYATENRKISAVSTYFESFPYRVNPETGIIDYDTLEKNAILYRPKVLVAGTSAYCRLIDYKRMREIADKCGAYLMVDMAHISGLIAAGVIPSPFEYADIVTTTTHKSLRGPRGAMIFFRRGVRSINPKTGKEVLYDLENPINFSVFPGHQGGPHNHTIAALATALKQAATPEFKEYQT... | folic acid metabolic process glycine biosynthetic process from serine L-serine catabolic process one-carbon metabolic process tetrahydrofolate interconversion tetrahydrofolate metabolic process cytoplasm; mating projection tip; plasma membrane glycine hydroxymethyltransferase activity pyridoxal phosphate binding serine... |
folic acid metabolic process glycine biosynthetic process from serine L-serine catabolic process one-carbon metabolic process tetrahydrofolate interconversion tetrahydrofolate metabolic process | cytoplasm; mitochondrion | glycine hydroxymethyltransferase activity pyridoxal phosphate binding serine binding zinc ion binding | Saccharomyces cerevisiae | Mitochondrion One-carbon metabolism Pyridoxal phosphate Reference proteome Transferase Transit peptide | MFPRASALAK | MFPRASALAKCMATVHRRGLLTSGAQSLVSKPVSEGDPEMFDILQQERHRQKHSITLIPSENFTSKAVMDLLGSELQNKYSEGYPGERYYGGNEIIDKSESLCQARALELYGLDPAKWGVNVQPLSGAPANLYVYSAIMNVGERLMGLDLPDGGHLSHGYQLKSGTPISFISKYFQSMPYHVDHTTGLIDYDNLQVLAKAFRPKVIVAGTSAYSRLIDYARFKEISQGCGAYLMSDMAHISGLVAANVVPSPFEHSDIVTTTTHKSLRGPRGAMIFFRKGIKSVTKKGKEIPYELEKKINFSVFPGHQGGPHNHTIGAMA... | folic acid metabolic process glycine biosynthetic process from serine L-serine catabolic process one-carbon metabolic process tetrahydrofolate interconversion tetrahydrofolate metabolic process cytoplasm; mitochondrion glycine hydroxymethyltransferase activity pyridoxal phosphate binding serine binding zinc ion binding... |
carotene biosynthetic process carotenoid biosynthetic process | membrane | 15-cis-phytoene synthase activity farnesyltranstransferase activity geranylgeranyl-diphosphate geranylgeranyltransferase activity intramolecular lyase activity lycopene beta cyclase activity | Neurospora crassa | Carotenoid biosynthesis Isomerase Membrane Multifunctional enzyme Reference proteome Transferase Transmembrane Transmembrane helix | MYDYAFVHLK | MYDYAFVHLKFTVPAAVLLTAIAYPILNRIHLIQTGFLVVVAFTAALPWDAYLIKHKVWSYPPEAIVGPRLLGIPFEELFFFVIQTYITALVYILFNKPVLHALHLNNQQNPPAWMRVVKVTGQVVLVALSVWGWNAAQVHQETSYLGLILVWACPFLLAIWTLAGRFILSLPWYATVLPMFLPTFYLWAVDEFALHRGTWSIGSGTKLDFCLFGKLDIEEATFFLVTNMLIVGGMAAFDQYLAVIYAFPTLFPKVNRYPTTHMLLQSRLINTSRYDLERIEGLREAVERLRLKSRSFYLANSLFSGRLRIDLILLYSFC... | carotene biosynthetic process carotenoid biosynthetic process membrane 15-cis-phytoene synthase activity farnesyltranstransferase activity geranylgeranyl-diphosphate geranylgeranyltransferase activity intramolecular lyase activity lycopene beta cyclase activity Neurospora crassa Carotenoid biosynthesis Isomerase Membra... |
endosomal lumen acidification Golgi lumen acidification proton transmembrane transport vacuolar acidification | endosome membrane; fungal-type vacuole membrane; Golgi apparatus; Golgi membrane; late endosome; proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase, V0 domain | ATPase binding phosphatidylinositol-4-phosphate binding proton-transporting ATPase activity, rotational mechanism | Saccharomyces cerevisiae | 3D-structure Acetylation Coiled coil Endosome Glycoprotein Golgi apparatus Hydrogen ion transport Ion transport Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport | MNQEEAIFRS | MNQEEAIFRSADMTYVQLYIPLEVIREVTFLLGKMSVFMVMDLNKDLTAFQRGYVNQLRRFDEVERMVGFLNEVVEKHAAETWKYILHIDDEGNDIAQPDMADLINTMEPLSLENVNDMVKEITDCESRARQLDESLDSLRSKLNDLLEQRQVIFECSKFIEVNPGIAGRATNPEIEQEERDVDEFRMTPDDISETLSDAFSFDDETPQDRGALGNDLTRNQSVEDLSFLEQGYQHRYMITGSIRRTKVDILNRILWRLLRGNLIFQNFPIEEPLLEGKEKVEKDCFIIFTHGETLLKKVKRVIDSLNGKIVSLNTRSSE... | endosomal lumen acidification Golgi lumen acidification proton transmembrane transport vacuolar acidification endosome membrane; fungal-type vacuole membrane; Golgi apparatus; Golgi membrane; late endosome; proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase complex; vacuolar proton-tr... |
glycine biosynthetic process threonine catabolic process | cytosol | L-allo-threonine aldolase activity threonine aldolase activity | Saccharomyces cerevisiae | Isopeptide bond Lyase Phosphoprotein Pyridoxal phosphate Reference proteome Ubl conjugation | MTEFELPPKY | MTEFELPPKYITAANDLRSDTFTTPTAEMMEAALEASIGDAVYGEDVDTVRLEQTVARMAGKEAGLFCVSGTLSNQIAIRTHLMQPPYSILCDYRAHVYTHEAAGLAILSQAMVVPVVPSNGDYLTLEDIKSHYVPDDGDIHGAPTRLISLENTLHGIVYPLEELVRIKAWCMENGLKLHCDGARIWNAAAQSGVPLKQYGEIFDSISICLSKSMGAPIGSVLVGNLKFVKKATHFRKQQGGGIRQSGMMARMALVNINNDWKSQLLYSHSLAHELAEYCEAKGIPLESPADTNFVFINLKAARMDPDVLVKKGLKYNVK... | glycine biosynthetic process threonine catabolic process cytosol L-allo-threonine aldolase activity threonine aldolase activity Saccharomyces cerevisiae Isopeptide bond Lyase Phosphoprotein Pyridoxal phosphate Reference proteome Ubl conjugation MTEFELPPKY MTEFELPPKYITAANDLRSDTFTTPTAEMMEAALEASIGDAVYGEDVDTVRLEQTVARMAGKE... |
dipeptide transport heme transmembrane transport protein transport response to radiation | ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; membrane | ATP binding ATP hydrolysis activity heme transmembrane transporter activity | Escherichia coli | ATP-binding Cell inner membrane Cell membrane Membrane Nucleotide-binding Peptide transport Protein transport Reference proteome Translocase Transport | MSTQEATLQQ | MSTQEATLQQPLLQAIDLKKHYPVKKGMFAPERLVKALDGVSFNLERGKTLAVVGESGCGKSTLGRLLTMIEMPTGGELYYQGQDLLKHDPQAQKLRRQKIQIVFQNPYGSLNPRKKVGQILEEPLLINTSLSKEQRREKALSMMAKVGLKTEHYDRYPHMFSGGQRQRIAIARGLMLDPDVVIADEPVSALDVSVRAQVLNLMMDLQQELGLSYVFISHDLSVVEHIADEVMVMYLGRCVEKGTKDQIFNNPRHPYTQALLSATPRLNPDDRRERIKLSGELPSPLNPPPGCAFNARCRRRFGPCTQLQPQLKDYGGQL... | dipeptide transport heme transmembrane transport protein transport response to radiation ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; membrane ATP binding ATP hydrolysis activity heme transmembrane transporter activity Escherichia coli ATP-binding Cell inner membrane Cell membra... |
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