Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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cellular response to glucocorticoid stimulus cellular response to steroid hormone stimulus chromatin organization positive regulation of transcription by RNA polymerase II | centrosome; cytoplasm; mitochondrion; nuclear speck; nucleus; spindle | DNA-binding transcription factor activity nuclear glucocorticoid receptor activity nuclear receptor activity sequence-specific DNA binding steroid binding steroid hormone binding zinc ion binding | Ovis aries | Chromatin regulator Cytoplasm Cytoskeleton DNA-binding Isopeptide bond Lipid-binding Metal-binding Mitochondrion Nucleus Phosphoprotein Receptor Reference proteome Steroid-binding Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | ASAAVSAAPT | ASAAVSAAPTEKEFPKTHSDVSSEQQNLKGQKGSNGGSMKLHTTDQSTFDIWRKKLQDLEFSSESPSKETSDSPWRSDILIDENCLLSPLAGEDDSFLLEGSSNEDCKPLLLPDAKPKIKDNGDLILPSPNSVPLPQVKTEKEDFIELCTPGVIKQEKLGPVYCQASFPGANIIGNKMSAISVHGVSTSGGQMYHYDMNTASLSQQQDQKPIFKVIPPIPVGSENWNRCQGSGDDSLTSLGTLNFSGRSVFSNGYSSPGMRPDVSSPPSSSSAATGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQH | cellular response to glucocorticoid stimulus cellular response to steroid hormone stimulus chromatin organization positive regulation of transcription by RNA polymerase II centrosome; cytoplasm; mitochondrion; nuclear speck; nucleus; spindle DNA-binding transcription factor activity nuclear glucocorticoid receptor acti... |
box C/D RNA 3'-end processing ribosomal small subunit biogenesis rRNA methylation sno(s)RNA metabolic process snoRNA localization | box C/D RNP complex; Cajal body; chromosome; dense fibrillar component; fibrillar center; granular component; nucleolus; nucleoplasm; nucleus; small-subunit processome | ATPase binding histone H2AQ104 methyltransferase activity RNA binding rRNA methyltransferase activity TFIID-class transcription factor complex binding | Mus musculus | Acetylation Isopeptide bond Methylation Methyltransferase Nucleus Phosphoprotein Reference proteome Ribonucleoprotein RNA-binding rRNA processing S-adenosyl-L-methionine Transferase Ubl conjugation | MKPGFSPRGG | MKPGFSPRGGGFGGRGGFGDRGGRGGGRGGRGGFGGGRGGFGGGGRGRGGGGGGFRGRGGGGGRGGGFQSGGNRGRGGGRGGKRGNQSGKNVMVEPHRHEGVFICRGKEDALVTKNLVPGESVYGEKRVSISEGDDKIEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGHFVISIKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLEPYERDHAVVVGVYR... | box C/D RNA 3'-end processing ribosomal small subunit biogenesis rRNA methylation sno(s)RNA metabolic process snoRNA localization box C/D RNP complex; Cajal body; chromosome; dense fibrillar component; fibrillar center; granular component; nucleolus; nucleoplasm; nucleus; small-subunit processome ATPase binding histone... |
box C/D RNA 3'-end processing rRNA methylation | box C/D RNP complex; mitotic spindle; nucleolus; nucleus; small-subunit processome | histone H2AQ104 methyltransferase activity mRNA binding RNA binding rRNA methyltransferase activity | Schizosaccharomyces pombe | Methyltransferase Nucleus Phosphoprotein Reference proteome Ribonucleoprotein RNA-binding rRNA processing S-adenosyl-L-methionine Transferase | MAYTPGSRGG | MAYTPGSRGGRGGSRGGRGGFNGGRGGFGGGRGGARGGGRGGARGGRGGRGGARGGRGGSSGGRGGAKGGAKVIIEPHRHAGVFIARGKEDLLVTRNLVPGESVYNEKRISVDSPDGTKVEYRVWNPFRSKLAAGILGGLDNIYIKPGARVLYLGAANGTSVSHVADVVGPEGLVYAVEFSHRSGRDLLNMAKKRTNVIPIVEDARHVQKYRMLVGMVDVVFADVAQPDQARIVALNAAAFLKNEGGVVISVKASCIDSTADAAVVFAREVKKMQEEKIKPQEQLTLEPYERDHCIIVGKYLRHQ | box C/D RNA 3'-end processing rRNA methylation box C/D RNP complex; mitotic spindle; nucleolus; nucleus; small-subunit processome histone H2AQ104 methyltransferase activity mRNA binding RNA binding rRNA methyltransferase activity Schizosaccharomyces pombe Methyltransferase Nucleus Phosphoprotein Reference proteome Rib... |
adult somatic muscle development oscillatory muscle contraction sarcomere organization skeletal muscle myosin thick filament assembly striated muscle myosin thick filament assembly | A band; striated muscle myosin thick filament | structural constituent of muscle structural molecule activity conferring elasticity | Drosophila melanogaster | Muscle protein Phosphoprotein Reference proteome | MADEEDPWGF | MADEEDPWGFDDGGEEEKAASTQAGTPAPPSKAPSVASDHKADSVVAGTPANEEAAPEEVEEIKAPPPPPEDDGYRKPVQLYRHWVRPKFLQYKYMYNYRTNYYDDVIDYIDKKQTGVAREIPRPQTWAERVLRTRNISGSDIDSYAPAKRDKQLIQTLAASIRTYNYHTKAYINQRYASVL | adult somatic muscle development oscillatory muscle contraction sarcomere organization skeletal muscle myosin thick filament assembly striated muscle myosin thick filament assembly A band; striated muscle myosin thick filament structural constituent of muscle structural molecule activity conferring elasticity Drosophil... |
calcium ion import canonical glycolysis carbohydrate phosphorylation cellular response to insulin stimulus cellular response to leptin stimulus glucose 6-phosphate metabolic process glucose catabolic process glucose homeostasis glucose metabolic process glycolytic process intracellular glucose homeostasis NADP metaboli... | cytosol; mitochondrion; nucleoplasm | ATP binding fructokinase activity glucokinase activity glucose binding glucose sensor activity mannokinase activity | Homo sapiens | 3D-structure Allosteric enzyme Alternative splicing ATP-binding Cytoplasm Diabetes mellitus Disease variant Glycolysis Kinase Mitochondrion Nucleotide-binding Nucleus Reference proteome Transferase | MLDDRARMEA | MLDDRARMEAAKKEKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLLFHGEA... | calcium ion import canonical glycolysis carbohydrate phosphorylation cellular response to insulin stimulus cellular response to leptin stimulus glucose 6-phosphate metabolic process glucose catabolic process glucose homeostasis glucose metabolic process glycolytic process intracellular glucose homeostasis NADP metaboli... |
amyloid-beta clearance amyloid-beta clearance by cellular catabolic process amyloid-beta metabolic process antigen processing and presentation of endogenous peptide antigen via MHC class I bradykinin catabolic process hormone catabolic process insulin catabolic process insulin metabolic process insulin receptor recycli... | basolateral plasma membrane; cell surface; cytoplasm; cytosol; cytosolic proteasome complex; endosome lumen; external side of plasma membrane; extracellular exosome; extracellular space; mitochondrion; nucleus; peroxisomal matrix; peroxisome | amyloid-beta binding ATP binding ATP hydrolysis activity beta-endorphin binding endopeptidase activity identical protein binding insulin binding metalloendopeptidase activity peptidase activity peptide binding peptide hormone binding protein homodimerization activity protein-containing complex binding ubiquitin-depende... | Rattus norvegicus | 3D-structure Allosteric enzyme ATP-binding Cell membrane Cytoplasm Direct protein sequencing Hydrolase Membrane Metal-binding Metalloprotease Nucleotide-binding Protease Reference proteome Secreted Zinc | MRNGLVWLLH | MRNGLVWLLHPALPSTLHSILGARPPPVKRLCGFPKQIYSTMNNPAIQRIEDHIVKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIPGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDASCKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVREELLKFHSTYYSSNLMAICVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIP... | amyloid-beta clearance amyloid-beta clearance by cellular catabolic process amyloid-beta metabolic process antigen processing and presentation of endogenous peptide antigen via MHC class I bradykinin catabolic process hormone catabolic process insulin catabolic process insulin metabolic process insulin receptor recycli... |
cellular response to magnesium ion circulatory system development gene expression kidney development negative regulation of apoptotic process post-embryonic development potassium ion import across plasma membrane potassium ion transport regulation of monoatomic ion transmembrane transport renal sodium ion absorption re... | monoatomic ion channel complex; plasma membrane | ATP binding ATP-activated inward rectifier potassium channel activity inward rectifier potassium channel activity peptide binding phosphatidylinositol-4,5-bisphosphate binding potassium ion binding | Rattus norvegicus | Alternative splicing ATP-binding Cell membrane Glycoprotein Ion channel Ion transport Membrane Nucleotide-binding Phosphoprotein Potassium Potassium transport Reference proteome Transmembrane Transmembrane helix Transport Voltage-gated channel | MGASERSVFR | MGASERSVFRVLIRALTERMFKHLRRWFITHIFGRSRQRARLVSKEGRCNIEFGNVDAQSRFIFFVDIWTTVLDLKWRYKMTVFITAFLGSWFLFGLLWYVVAYVHKDLPEFYPPDNRTPCVENINGMTSAFLFSLETQVTIGYGFRFVTEQCATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANLRKSLLIGSHIYGKLLKTTITPEGETIILDQTNINFVVDAGNENLFFISPLTIYHIIDHNSPFFHMAAETLSQQDFELVVFLDGTVESTSATCQVRTSYVPEEVL... | cellular response to magnesium ion circulatory system development gene expression kidney development negative regulation of apoptotic process post-embryonic development potassium ion import across plasma membrane potassium ion transport regulation of monoatomic ion transmembrane transport renal sodium ion absorption re... |
cardiac muscle cell action potential cardiac muscle cell action potential involved in contraction cellular response to mechanical stimulus magnesium ion transport membrane repolarization during action potential membrane repolarization during cardiac muscle cell action potential positive regulation of potassium ion tran... | dendrite; dendritic spine; glutamatergic synapse; intercalated disc; membrane; neuronal cell body; plasma membrane; postsynaptic membrane; T-tubule; voltage-gated potassium channel complex | identical protein binding inward rectifier potassium channel activity phosphatidylinositol-4,5-bisphosphate binding voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization | Mus musculus | 3D-structure Ion channel Ion transport Lipoprotein Membrane Myristate Potassium Potassium transport Reference proteome S-nitrosylation Transmembrane Transmembrane helix Transport Voltage-gated channel | MGSVRTNRYS | MGSVRTNRYSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCRSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLDTSKVSKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEI... | cardiac muscle cell action potential cardiac muscle cell action potential involved in contraction cellular response to mechanical stimulus magnesium ion transport membrane repolarization during action potential membrane repolarization during cardiac muscle cell action potential positive regulation of potassium ion tran... |
cellular response to growth factor stimulus chemical synaptic transmission inorganic cation transmembrane transport monoatomic ion transmembrane transport regulation of presynaptic membrane potential response to cocaine response to ethanol serotonin receptor signaling pathway | axon; cleavage furrow; glutamatergic synapse; neuron projection; neuronal cell body; postsynaptic membrane; presynaptic membrane; serotonin-activated cation-selective channel complex; synapse | acetylcholine-gated monoatomic cation-selective channel activity identical protein binding ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential serotonin binding serotonin-gated monoatomic cation channel activity | Rattus norvegicus | Cell membrane Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MPLCIPQVLL | MPLCIPQVLLALFLSVLIAQGEGSRRRATQAHSTTQPALLRLSDHLLANYKKGVRPVRDWRKPTLVSIDVIMYAILNVDEKNQVLTTYIWYRQFWTDEFLQWTPEDFDNVTKLSIPTDSIWVPDILINEFVDVGKSPSIPYVYVHHQGEVQNYKPLQLVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRTPEEVRSDKSIFINQGEWELLGVFTKFQEFSIETSNSYAEMKFYVVIRRRPLFYAVSLLLPSIFLMVVDIVGFCLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMAL... | cellular response to growth factor stimulus chemical synaptic transmission inorganic cation transmembrane transport monoatomic ion transmembrane transport regulation of presynaptic membrane potential response to cocaine response to ethanol serotonin receptor signaling pathway axon; cleavage furrow; glutamatergic synaps... |
clathrin-dependent endocytosis protein folding synaptic vesicle endocytosis ubiquitin-dependent ERAD pathway | axon; dendrite cytoplasm; dendritic spine; endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum quality control compartment; glutamatergic synapse; lumenal side of endoplasmic reticulum membrane; melanosome membrane; membrane; mitochondria-associated endoplasmic reticulum membrane; mitochondrial... | apolipoprotein binding calcium ion binding carbohydrate binding ionotropic glutamate receptor binding unfolded protein binding | Mus musculus | Acetylation Calcium Chaperone Disulfide bond Endoplasmic reticulum Lectin Lipoprotein Membrane Metal-binding Mitochondrion Palmitate Phosphoprotein Reference proteome Repeat Signal Transmembrane Transmembrane helix Ubl conjugation | MEGKWLLCLL | MEGKWLLCLLLVLGTAAVEAHDGHDDDAIDIEDDLDDVIEEVEDSKSKSDASTPPSPKVTYKAPVPTGEVYFADSFDRGSLSGWILSKAKKDDTDDEIAKYDGKWEVDEMKETKLPGDKGLVLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTAELSLDQFHDKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGVYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIADPDAVKPDDWDEDAPSKIPDEEATK... | clathrin-dependent endocytosis protein folding synaptic vesicle endocytosis ubiquitin-dependent ERAD pathway axon; dendrite cytoplasm; dendritic spine; endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum quality control compartment; glutamatergic synapse; lumenal side of endoplasmic reticulum m... |
clathrin-dependent endocytosis protein folding synaptic vesicle endocytosis ubiquitin-dependent ERAD pathway | axon; dendrite cytoplasm; dendritic spine; endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum quality control compartment; glutamatergic synapse; melanosome membrane; membrane; mitochondria-associated endoplasmic reticulum membrane; mitochondrial membrane; neuronal cell body; nuclear membrane;... | apolipoprotein binding calcium ion binding carbohydrate binding ionotropic glutamate receptor binding unfolded protein binding | Rattus norvegicus | Acetylation Calcium Chaperone Direct protein sequencing Disulfide bond Endoplasmic reticulum Lectin Lipoprotein Membrane Metal-binding Mitochondrion Palmitate Phosphoprotein Reference proteome Repeat Signal Transmembrane Transmembrane helix Ubl conjugation | MEGKWLLCLL | MEGKWLLCLLLVLGTAAIQAHDGHDDDMIDIEDDLDDVIEEVEDSKSKSDTSTPPSPKVTYKAPVPTGEVYFADSFDRGSLSGWILSKAKKDDTDDEIAKYDGKWEVDEMKETKLPGDKGLVLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTSELNLDQFHDKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGVYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIADPDAVKPDDWDEDAPSKIPDEEATK... | clathrin-dependent endocytosis protein folding synaptic vesicle endocytosis ubiquitin-dependent ERAD pathway axon; dendrite cytoplasm; dendritic spine; endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum quality control compartment; glutamatergic synapse; melanosome membrane; membrane; mitochon... |
cell division G2/M transition of mitotic cell cycle phosphorylation regulation of circadian rhythm rhythmic process | cytosol; nucleus | ATP binding cyclin-dependent protein serine/threonine kinase activity protein serine kinase activity protein serine/threonine kinase activity RNA polymerase II CTD heptapeptide repeat kinase activity | Xenopus laevis | ATP-binding Biological rhythms Cell cycle Cell division Kinase Mitosis Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MDEYTKIEKI | MDEYTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHPNIVCLLDVLMQDSRLYLIFEFLSMDLKKYLDSIPSGQYIDTMLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDSKGVIKLADFGLARAFGIPVRVYTHEVVTLWYRAPEVLLGSVRYSTPVDVWSIGTIFAEIATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNSFPKWKGGSLSANVKNIDKDGLDLLAKMLIYDPAKRISARKALLHPYFDDLDKSSLPDNQIRN | cell division G2/M transition of mitotic cell cycle phosphorylation regulation of circadian rhythm rhythmic process cytosol; nucleus ATP binding cyclin-dependent protein serine/threonine kinase activity protein serine kinase activity protein serine/threonine kinase activity RNA polymerase II CTD heptapeptide repeat kin... |
cholesterol homeostasis gluconeogenesis glucose 6-phosphate metabolic process glucose homeostasis glucose-6-phosphate transport glycogen catabolic process glycogen metabolic process multicellular organism growth regulation of gene expression steroid metabolic process triglyceride metabolic process urate metabolic proce... | endoplasmic reticulum membrane; membrane | glucose-6-phosphatase activity phosphate ion binding phosphotransferase activity, alcohol group as acceptor | Homo sapiens | Alternative splicing Disease variant Endoplasmic reticulum Gluconeogenesis Glycogen storage disease Glycoprotein Hydrolase Membrane Reference proteome Transmembrane Transmembrane helix | MEEGMNVLHD | MEEGMNVLHDFGIQSTHYLQVNYQDSQDWFILVSVIADLRNAFYVLFPIWFHLQEAVGIKLLWVAVIGDWLNLVFKWILFGQRPYWWVLDTDYYSNTSVPLIKQFPVTCETGPGSPSGHAMGTAGVYYVMVTSTLSIFQGKIKPTYRFRCLNVILWLGFWAVQLNVCLSRIYLAAHFPHQVVAGVLSGIAVAETFSHIHSIYNASLKKYFLITFFLFSFAIGFYLLLKGLGVDLLWTLEKAQRWCEQPEWVHIDTTPFASLLKNLGTLFGLGLALNSSMYRESCKGKLSKWLPFRLSSIVASLVLLHVFDSLKPPSQVEL... | cholesterol homeostasis gluconeogenesis glucose 6-phosphate metabolic process glucose homeostasis glucose-6-phosphate transport glycogen catabolic process glycogen metabolic process multicellular organism growth regulation of gene expression steroid metabolic process triglyceride metabolic process urate metabolic proce... |
cholesterol homeostasis gluconeogenesis glucose 6-phosphate metabolic process glucose homeostasis glucose-6-phosphate transport glycogen catabolic process glycogen metabolic process lipid homeostasis multicellular organism growth regulation of gene expression steroid metabolic process triglyceride metabolic process ura... | endoplasmic reticulum; endoplasmic reticulum membrane; membrane | glucose-6-phosphatase activity phosphate ion binding phosphotransferase activity, alcohol group as acceptor | Mus musculus | Endoplasmic reticulum Gluconeogenesis Glycoprotein Hydrolase Membrane Reference proteome Transmembrane Transmembrane helix | MEEGMNILHD | MEEGMNILHDFGIQSTRYLQVNYQDSQDWFILVSVIADLRNAFYVLFPIWFHLKETVGINLLWVAVVGDWFNLVFKWILFGQRPYWWVLDTDYYSNSSVPIIKQFPVTCETGPGSPSGHAMGAAGVYYVMVTSTLAIFRGKKKPTYGFRCLNVILWLGFWAVQLNVCLSRIYLAAHFPHQVVAGVLSGIAVAETFSHIRGIYNASLRKYCLITIFLFGFALGFYLLLKGLGVDLLWTLEKAKRWCERPEWVHLDTTPFASLFKNLGTLLGLGLALNSSMYRKSCKGELSKLLPFRFACIVASLVLLHLFDSLKPPSQVEL... | cholesterol homeostasis gluconeogenesis glucose 6-phosphate metabolic process glucose homeostasis glucose-6-phosphate transport glycogen catabolic process glycogen metabolic process lipid homeostasis multicellular organism growth regulation of gene expression steroid metabolic process triglyceride metabolic process ura... |
post-embryonic development response to corticosterone response to nutrient levels response to peptide hormone response to prostaglandin E response to steroid hormone response to vitamin A response to xenobiotic stimulus thyroid hormone transport | extracellular space | hormone binding serine-type endopeptidase inhibitor activity thyroid hormone transmembrane transporter activity | Rattus norvegicus | Direct protein sequencing Glycoprotein Reference proteome Secreted Signal | MSMFFYLFLL | MSMFFYLFLLVLGLQATIHCAPHNSSEGKVTTCHLPQQNATLYKMPSINADFAFRLYRKLSVENPDLNIFFSPVSISAALAMLSFGSGSSTQTQILEVLGFNLTDTPVKELQQGFQHLICSLNFPNNELELQMGNAVFIGQQLKPLAKFLDDVKTLYETEVFSTDFSNVSAAQHEINSYVEKQTKGKIVGLIQDLKLNIIMILVNYIHFKAQWANPFRVSKTEESSNFSVDKSTTVQVPMMHQLEQYYHYVDVELNCTVLQMDYSANALALFVLPKEGHMEWVEAAMSSKTLKKWNHLLQKGWVELFVPKFSISATYDLG... | post-embryonic development response to corticosterone response to nutrient levels response to peptide hormone response to prostaglandin E response to steroid hormone response to vitamin A response to xenobiotic stimulus thyroid hormone transport extracellular space hormone binding serine-type endopeptidase inhibitor ac... |
anatomical structure morphogenesis cell differentiation cellular response to starvation chromatin organization hematopoietic stem cell homeostasis intracellular glucose homeostasis negative regulation of cell population proliferation positive regulation of hepatocyte differentiation positive regulation of transcription... | actin cytoskeleton; cytosol; nucleoplasm; nucleus | DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific protein domain specific binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA binding transcription cis-... | Mus musculus | Activator Chromatin regulator Developmental protein Differentiation DNA-binding Nucleus Reference proteome Spermatogenesis Transcription Transcription regulation | MLGSVKMEAH | MLGSVKMEAHDLAEWSYYPEAGEVYSPVNPVPTMAPLNSYMTLNPLSSPYPPGGLQASPLPTGPLAPPAPTAPLGPTFPSLGTGGSTGGSASGYVAPGPGLVHGKEMAKGYRRPLAHAKPPYSYISLITMAIQQAPGKMLTLSEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWALHPSSGNMFENGCYLRRQKRFKLEEKAKKGNSATSASRNGTAGSATSATTTAATAVTSPAQPQPTPSEPEAQSGDDVGGLDCASPPSSTPYFSGLELPGELKLDAPYNFNHPFSINNLMSEQTSTP... | anatomical structure morphogenesis cell differentiation cellular response to starvation chromatin organization hematopoietic stem cell homeostasis intracellular glucose homeostasis negative regulation of cell population proliferation positive regulation of hepatocyte differentiation positive regulation of transcription... |
endosome to melanosome transport intracellular protein transport melanosome assembly melanosome organization platelet dense granule organization vesicle-mediated transport | AP-1 adaptor complex; clathrin-coated vesicle; cytosol; early endosome; intracellular membrane-bounded organelle; lysosomal membrane; trans-Golgi network; trans-Golgi network membrane | clathrin adaptor activity | Mus musculus | 3D-structure Acetylation Cytoplasmic vesicle Golgi apparatus Membrane Phosphoprotein Protein transport Reference proteome Transport | MSASAVYVLD | MSASAVYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWIKHNNLYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDFGYPQTTDSKILQEYITQEGHKLETGAPRPPATVTNAVSWRSEGIKYRKNEVFLDVIEAVNLLVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRGKSKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMVKAKSQFKRRSTANNVEIHIPVPNDA... | endosome to melanosome transport intracellular protein transport melanosome assembly melanosome organization platelet dense granule organization vesicle-mediated transport AP-1 adaptor complex; clathrin-coated vesicle; cytosol; early endosome; intracellular membrane-bounded organelle; lysosomal membrane; trans-Golgi ne... |
dendrite morphogenesis DNA repair DNA replication | DNA replication factor C complex; nucleus | ATP binding ATP hydrolysis activity DNA binding DNA clamp loader activity | Drosophila melanogaster | Activator ATP-binding DNA replication DNA-binding Nucleotide-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MQRGIDSFFK | MQRGIDSFFKRLPAKAKSAEAENGETPSKAPKRRKAVIISSDEDEVVSPPETKKRKASKTASSEDDVVAATPEPIAKKARNGQKPALSKLKRHVDPTELFGGETKRVIVPKPKTKAVLEFENEDIDRSLMEVDLDESIKEAAPEKKVHSITRSSPSPKRAKNSSPEPPKPKSTKSKATTPRVKKEKPAADLESSVLTDEERHERKRASAVLYQKYKNRSSCLNPGSKEIPKGSPDCLSGLTFVVTGVLESMEREEAESVIKEYGGKVMTVVGKKLKYLVVGEEAGPKKLAVAEELNIPILSEDGLFDLIREKSGIAKQVK... | dendrite morphogenesis DNA repair DNA replication DNA replication factor C complex; nucleus ATP binding ATP hydrolysis activity DNA binding DNA clamp loader activity Drosophila melanogaster Activator ATP-binding DNA replication DNA-binding Nucleotide-binding Nucleus Phosphoprotein Reference proteome Transcription Trans... |
apical protein localization cilium assembly embryo development ending in birth or egg hatching intracellular protein transport nematode larval development receptor localization to non-motile cilium vesicle-mediated transport vulval development | AP-1 adaptor complex; clathrin-coated vesicle; dendrite | clathrin adaptor activity | Caenorhabditis elegans | Alternative splicing Cell projection Cytoplasmic vesicle Golgi apparatus Membrane Protein transport Reference proteome Transport | MATSAMFILD | MATSAMFILDLKGKTIISRNYRGDIDMTAIDKFIHLLMEKEEEGSAAPVLTYQDTNFVFIKHTNIYLVSACRSNVNVTMILSFLYKCVEVFSEYFKDVEEESVRDNFVVIYELLDEMMDFGFPQTTESRILQEYITQEGQKLISAPRPPMAVTNAVSWRSEGIKYRKNEVFLDVIESVNMLASANGTVLQSEIVGSVKMRVYLTGMPELRLGLNDKVLFEGSGRGKSKSVELEDVKFHQCVRLSRFDTDRTISFIPPDGAFELMSYRLTTVVKPLIWIETSIERHSHSRVSFIIKAKSQFKRRSTANNVEIIIPVPSDAD... | apical protein localization cilium assembly embryo development ending in birth or egg hatching intracellular protein transport nematode larval development receptor localization to non-motile cilium vesicle-mediated transport vulval development AP-1 adaptor complex; clathrin-coated vesicle; dendrite clathrin adaptor act... |
body morphogenesis clathrin-dependent endocytosis intracellular protein transport necroptotic process positive regulation of Wnt protein secretion protein localization to non-motile cilium receptor-mediated endocytosis regulation of neurogenesis | AP-2 adaptor complex; cytoplasmic vesicle; periciliary membrane compartment; synapse; synaptic vesicle | clathrin adaptor activity | Caenorhabditis elegans | Alternative splicing Cell membrane Coated pit Endocytosis Membrane Protein transport Reference proteome Transport | MIGGLFVYNH | MIGGLFVYNHKGEVLISRIYRDDVTRNAVDAFRVNVIHARQQVRSPVTNMARTSFFHVKRGNVWICAVTRQNVNAAMVFEFLKRFADTMQSYFGKLNEENVKNNFVLIYELLDEILDFGYPQNTDPGVLKTFITQQGVRTADAPVPVTKEEQSQITSQVTGQIGWRREGIKYRRNELFLDVIEYVNLLMNQQGQVLSAHVAGKVAMKSYLSGMPECKFGINDKITIEGKSKPGSDDPNKASRAAVAIDDCQFHQCVKLTKFETEHAISFIPPDGEYELMRYRTTKDIQLPFRVIPLVREVSRNKMEVKVVVKSNFKPSLL... | body morphogenesis clathrin-dependent endocytosis intracellular protein transport necroptotic process positive regulation of Wnt protein secretion protein localization to non-motile cilium receptor-mediated endocytosis regulation of neurogenesis AP-2 adaptor complex; cytoplasmic vesicle; periciliary membrane compartmen... |
endoplasmic reticulum to Golgi vesicle-mediated transport intra-Golgi vesicle-mediated transport intracellular protein transport retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum | COPI vesicle coat; cytosol; endoplasmic reticulum membrane; Golgi membrane; transport vesicle | structural molecule activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Coiled coil Cytoplasm Cytoplasmic vesicle Direct protein sequencing ER-Golgi transport Golgi apparatus Membrane Phosphoprotein Primary microcephaly Protein transport Reference proteome Repeat Transport WD repeat | MPLRLDIKRK | MPLRLDIKRKLTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVASLRGSNNVALGYDEGSIIVKLGREEPAMSMDANGKIIWAKHS... | endoplasmic reticulum to Golgi vesicle-mediated transport intra-Golgi vesicle-mediated transport intracellular protein transport retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum COPI vesicle coat; cytosol; endoplasmic reticulum membrane; Golgi membrane; transport vesicle structural molecule activit... |
actin cytoskeleton organization actin filament uncapping cardiac muscle cell development cell adhesion focal adhesion assembly microspike assembly muscle cell development negative regulation of potassium ion transmembrane transporter activity negative regulation of potassium ion transport negative regulation of protein... | actin filament; cell junction; cell projection; cortical actin cytoskeleton; cytoskeleton; cytosol; dendritic spine; extracellular exosome; extracellular region; filopodium; focal adhesion; glutamatergic synapse; platelet alpha granule lumen; postsynaptic actin cytoskeleton; postsynaptic density membrane; postsynaptic ... | actin filament binding calcium ion binding cytoskeletal protein binding FATZ binding identical protein binding integrin binding LIM domain binding nuclear receptor coactivator activity phosphatidylinositol-4,5-bisphosphate binding protein domain specific binding structural constituent of muscle titin binding titin Z do... | Homo sapiens | 3D-structure Actin-binding Alternative splicing Calcium Cardiomyopathy Cytoplasm Disease variant Metal-binding Phosphoprotein Reference proteome Repeat Ubl conjugation | MNQIEPGVQY | MNQIEPGVQYNYVYDEDEYMIQEEEWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNIQNFHTSWKDGLGLCALIHRHRPDLIDYSKLNKDDPIGNINLAMEIAEKHLDIPKMLDAEDIVNTPKPDERAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENERLMEEYERLASELLEWIRRTIPWLENRTPEKTMQAMQKKL... | actin cytoskeleton organization actin filament uncapping cardiac muscle cell development cell adhesion focal adhesion assembly microspike assembly muscle cell development negative regulation of potassium ion transmembrane transporter activity negative regulation of potassium ion transport negative regulation of protein... |
cholesterol efflux cholesterol homeostasis cholesterol metabolic process cholesterol storage low-density lipoprotein particle clearance macrophage derived foam cell differentiation positive regulation of amyloid precursor protein biosynthetic process very-low-density lipoprotein particle assembly | endoplasmic reticulum; endoplasmic reticulum membrane; membrane | cholesterol binding cholesterol O-acyltransferase activity fatty-acyl-CoA binding identical protein binding sterol O-acyltransferase activity | Homo sapiens | 3D-structure Acetylation Acyltransferase Alternative splicing Cholesterol metabolism Disulfide bond Endoplasmic reticulum Lipid metabolism Membrane Phosphoprotein Reference proteome Steroid metabolism Sterol metabolism Transferase Transmembrane Transmembrane helix | MVGEEKMSLR | MVGEEKMSLRNRLSKSRENPEEDEDQRNPAKESLETPSNGRIDIKQLIAKKIKLTAEAEELKPFFMKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSVLEGEKNNHRAKDLRAPPEQGKIFIARRSLLDELLEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFSLLSYAFGKFPTVVWTWWIMFLSTFSVPYFLFQHWATGYSKSSHPLIRSLFHGFLFMIFQIGVLGFGPTYVVLAYTLPPASRFIIIFEQIRFVMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRNPTVRW... | cholesterol efflux cholesterol homeostasis cholesterol metabolic process cholesterol storage low-density lipoprotein particle clearance macrophage derived foam cell differentiation positive regulation of amyloid precursor protein biosynthetic process very-low-density lipoprotein particle assembly endoplasmic reticulum;... |
actin cytoskeleton organization actin filament bundle assembly barbed-end actin filament capping cellular response to calcium ion positive regulation of adherens junction organization positive regulation of establishment of endothelial barrier positive regulation of protein binding | adherens junction; cytoplasm; cytoskeleton; cytosol; F-actin capping protein complex; focal adhesion; nuclear body; nucleoplasm; nucleus; plasma membrane; postsynaptic density | actin binding actin filament binding cadherin binding calmodulin binding protein dimerization activity protein heterodimerization activity protein homodimerization activity RNA binding RNA polymerase II-specific DNA-binding transcription factor binding spectrin binding | Homo sapiens | Acetylation Actin-binding Alternative splicing Calmodulin-binding Cell membrane Cytoplasm Cytoskeleton Direct protein sequencing Membrane Phosphoprotein Reference proteome | MNGDSRAAVV | MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSMILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMSLGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHIHTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILRNHGLVSVGESVEEAFYYIHN... | actin cytoskeleton organization actin filament bundle assembly barbed-end actin filament capping cellular response to calcium ion positive regulation of adherens junction organization positive regulation of establishment of endothelial barrier positive regulation of protein binding adherens junction; cytoplasm; cytoske... |
actin cytoskeleton organization actin filament bundle assembly barbed-end actin filament capping hemopoiesis leukocyte migration leukocyte tethering or rolling positive regulation of protein binding protein-containing complex assembly synapse assembly | cytoplasmic vesicle; cytoskeleton; cytosol; F-actin capping protein complex; plasma membrane; plasma membrane raft; postsynaptic density | actin binding actin filament binding calmodulin binding protein dimerization activity protein heterodimerization activity protein homodimerization activity protein kinase binding spectrin binding structural constituent of cytoskeleton | Homo sapiens | Actin-binding Alternative splicing Calmodulin-binding Cell membrane Cytoplasm Cytoskeleton Direct protein sequencing Membrane Phosphoprotein Reference proteome | MSEETVPEAA | MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQSPSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHTADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEVTASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAVSAMKWGLLPVSHNALLVGDMAYYDFNGEMEQEADRINLQKCLGPTCKILVLRNHGVVALGDTVEEAFYKIFHLQAACEIQVSAL... | actin cytoskeleton organization actin filament bundle assembly barbed-end actin filament capping hemopoiesis leukocyte migration leukocyte tethering or rolling positive regulation of protein binding protein-containing complex assembly synapse assembly cytoplasmic vesicle; cytoskeleton; cytosol; F-actin capping protein ... |
angiogenesis cell surface receptor signaling pathway decidualization embryo implantation endothelial tube morphogenesis neural retina development neutrophil chemotaxis odontogenesis of dentin-containing tooth photoreceptor cell maintenance positive regulation of endothelial cell migration positive regulation of interle... | acrosomal membrane; basolateral plasma membrane; endoplasmic reticulum membrane; endosome; extracellular exosome; focal adhesion; Golgi membrane; intracellular membrane-bounded organelle; melanosome; membrane; mitochondrion; photoreceptor inner segment; photoreceptor outer segment; plasma membrane; sarcolemma | cadherin binding mannose binding signaling receptor activity virus receptor activity | Homo sapiens | 3D-structure Alternative promoter usage Alternative splicing Angiogenesis Blood group antigen Cell membrane Cell projection Direct protein sequencing Disulfide bond Endoplasmic reticulum Endosome Glycoprotein Host cell receptor for virus entry Host-virus interaction Immunoglobulin domain Lectin Mannose-binding Membrane... | MAAALFVLLG | MAAALFVLLGFALLGTHGASGAAGFVQAPLSQQRWVGGSVELHCEAVGSPVPEIQWWFEGQGPNDTCSQLWDGARLDRVHIHATYHQHAASTISIDTLVEEDTGTYECRASNDPDRNHLTRAPRVKWVRAQAVVLVLEPGTVFTTVEDLGSKILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQKTEFKVDSDDQWGEYSCVFLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRS... | angiogenesis cell surface receptor signaling pathway decidualization embryo implantation endothelial tube morphogenesis neural retina development neutrophil chemotaxis odontogenesis of dentin-containing tooth photoreceptor cell maintenance positive regulation of endothelial cell migration positive regulation of interle... |
axis specification BMP signaling pathway convergent extension involved in gastrulation heart looping left/right pattern formation neuron development nodal signaling pathway positive regulation of cell division regulation of epiboly involved in gastrulation with mouth forming second regulation of nodal signaling pathway... | extracellular space; protein-containing complex | cytokine activity growth factor activity | Danio rerio | Cleavage on pair of basic residues Disulfide bond Glycoprotein Growth factor Mitogen Reference proteome Secreted Signal | MFLVLLRACL | MFLVLLRACLLTLSLCSPAEDDGLVQEKLFLSSMGLWSRPKPSHHAAVPSQMWKIFKQASKQTVNDPCVVSEYGVRGNIVRFMQDQGSLISAPAVHSFNCVRKHLFFNMSVLEEVEQLSLAQLEMKFKQDLLLLGPHVFSVDLYRVLKTTLKGVTHESSRKLLQSQTLSPGAHASVLVNLTNLAQSWRKPEKNFGMQLELQVMHLNNMLHDHAYVQIPDIHATLVVVSLNPLQCRSRRKRSASYYLPVTPSNVCKPRRLYIDFKDVGWQDWIIAPQGYLANYCHGECPFPLSESLNGTNHAILQTLVHSFDPKGTPQPCC... | axis specification BMP signaling pathway convergent extension involved in gastrulation heart looping left/right pattern formation neuron development nodal signaling pathway positive regulation of cell division regulation of epiboly involved in gastrulation with mouth forming second regulation of nodal signaling pathway... |
cellular response to tetrahydrofolate folic acid metabolic process glycine biosynthetic process from serine glycine metabolic process L-serine catabolic process L-serine metabolic process protein homotetramerization purine nucleobase biosynthetic process tetrahydrofolate interconversion tetrahydrofolate metabolic proce... | cytosol; nucleoplasm | glycine hydroxymethyltransferase activity mRNA 5'-UTR binding mRNA regulatory element binding translation repressor activity protein homodimerization activity pyridoxal phosphate binding serine binding | Ovis aries | Acetylation Cytoplasm Direct protein sequencing One-carbon metabolism Pyridoxal phosphate Reference proteome Transferase | MAAPVNKAPR | MAAPVNKAPRDADLWSLHEKMLAQPLKDNDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFIDELEVLCQKRALQVYGLDPECWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPRLIIAGTSCYSRNLDYARLRKIADDNGAYLMADMAHISGLVAAGVVPSPFEHCHVVSTTTHKTLRGCRAGMIFYRKGVRSVDPKTGKETRYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAM... | cellular response to tetrahydrofolate folic acid metabolic process glycine biosynthetic process from serine glycine metabolic process L-serine catabolic process L-serine metabolic process protein homotetramerization purine nucleobase biosynthetic process tetrahydrofolate interconversion tetrahydrofolate metabolic proce... |
cellular response to organic substance negative regulation of membrane protein ectodomain proteolysis negative regulation of metalloendopeptidase activity response to cytokine response to hormone visual perception | basement membrane; collagen-containing extracellular matrix; extracellular matrix; extracellular region; extracellular space; nucleus; platelet dense granule lumen | metal ion binding metalloendopeptidase inhibitor activity protease binding | Homo sapiens | 3D-structure Direct protein sequencing Disease variant Disulfide bond Extracellular matrix Metal-binding Metalloenzyme inhibitor Metalloprotease inhibitor Protease inhibitor Reference proteome Secreted Sensory transduction Signal Vision Zinc | MTPWLGLIVL | MTPWLGLIVLLGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEGPFGTLVYTIKQMKMYRGFTKMPHVQYIHTEASESLCGLKLEVNKYQYLLTGRVYDGKMYTGLCNFVERWDQLTLSQRKGLNYRYHLGCNCKIKSCYYLPCFVTSKNECLWTDMLSNFGYPGYQSKHYACIRQKGGYCSWYRGWAPPDKSIINATDP | cellular response to organic substance negative regulation of membrane protein ectodomain proteolysis negative regulation of metalloendopeptidase activity response to cytokine response to hormone visual perception basement membrane; collagen-containing extracellular matrix; extracellular matrix; extracellular region; e... |
desensitization of G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway phosphorylation receptor internalization signal transduction | cell projection; cytosol; plasma membrane; postsynapse; presynapse | ATP binding beta-adrenergic receptor kinase activity G protein-coupled receptor binding G protein-coupled receptor kinase activity protein kinase activity | Homo sapiens | ATP-binding Cell projection Kinase Nucleotide-binding Reference proteome Serine/threonine-protein kinase Synapse Transferase Ubl conjugation | MADLEAVLAD | MADLEAVLADVSYLMAMEKSKATPAARASKRIVLPEPSIRSVMQKYLAERNEITFDKIFNQKIGFLLFKDFCLNEINEAVPQVKFYEEIKEYEKLDNEEDRLCRSRQIYDAYIMKELLSCSHPFSKQAVEHVQSHLSKKQVTSTLFQPYIEEICESLRGDIFQKFMESDKFTRFCQWKNVELNIHLTMNEFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATEIILGLEHMHNRFVVYRDLKP... | desensitization of G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway phosphorylation receptor internalization signal transduction cell projection; cytosol; plasma membrane; postsynapse; presynapse ATP binding beta-adrenergic receptor kinase activity G protein-coupled receptor bin... |
cell differentiation floral meristem determinacy flower development meristem structural organization positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II | nucleus | DNA binding DNA-binding transcription factor activity protein heterodimerization activity RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription cis-regulatory region binding | Arabidopsis thaliana | Activator Coiled coil Developmental protein Differentiation DNA-binding Flowering Nucleus Reference proteome Transcription Transcription regulation | MGRGRVQLKR | MGRGRVQLKRIENKINRQVTFSKRRAGLLKKAHEISVLCDAEVALVVFSHKGKLFEYSTDSCMEKILERYERYSYAERQLIAPESDVNTNWSMEYNRLKAKIELLERNQRHYLGEDLQAMSPKELQNLEQQLDTALKHIRTRKNQLMYESINELQKKEKAIQEQNSMLSKQIKEREKILRAQQEQWDQQNQGHNMPPPLPPQQHQIQHPYMLSHQPSPFLNMGGLYQEDDPMAMRRNDLELTLEPVYNCNLGCFAA | cell differentiation floral meristem determinacy flower development meristem structural organization positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II nucleus DNA binding DNA-binding transcription factor activity protein heterodimerization activity RNA polymera... |
cell differentiation positive regulation of transcription by RNA polymerase II specification of floral organ identity | nucleus | DNA-binding transcription factor activity protein dimerization activity RNA polymerase II transcription regulatory region sequence-specific DNA binding | Arabidopsis thaliana | Activator Coiled coil Developmental protein Differentiation DNA-binding Flowering Nucleus Reference proteome Transcription Transcription regulation | MARGKIQIKR | MARGKIQIKRIENQTNRQVTYSKRRNGLFKKAHELTVLCDARVSIIMFSSSNKLHEYISPNTTTKEIVDLYQTISDVDVWATQYERMQETKRKLLETNRNLRTQIKQRLGECLDELDIQELRRLEDEMENTFKLVRERKFKSLGNQIETTKKKNKSQQDIQKNLIHELELRAEDPHYGLVDNGGDYDSVLGYQIEGSRAYALRFHQNHHHYYPNHGLHAPSASDIITFHLLE | cell differentiation positive regulation of transcription by RNA polymerase II specification of floral organ identity nucleus DNA-binding transcription factor activity protein dimerization activity RNA polymerase II transcription regulatory region sequence-specific DNA binding Arabidopsis thaliana Activator Coiled coil... |
amyloid fibril formation mRNA stabilization positive regulation of double-strand break repair via homologous recombination protein homooligomerization regulation of DNA-templated transcription regulation of RNA splicing regulation of transcription by RNA polymerase II RNA splicing | cytoplasm; intracellular non-membrane-bounded organelle; nucleoplasm; nucleus | chromatin binding DNA binding identical protein binding metal ion binding molecular condensate scaffold activity mRNA 3'-UTR binding RNA binding transcription coactivator activity transcription coregulator activity | Homo sapiens | 3D-structure Alternative splicing Amyotrophic lateral sclerosis Chromosomal rearrangement Direct protein sequencing Disease variant DNA-binding Isopeptide bond Metal-binding Methylation Neurodegeneration Nucleus Phosphoprotein Proto-oncogene Reference proteome Repeat RNA-binding Ubl conjugation Zinc Zinc-finger | MASNDYTQQA | MASNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQP... | amyloid fibril formation mRNA stabilization positive regulation of double-strand break repair via homologous recombination protein homooligomerization regulation of DNA-templated transcription regulation of RNA splicing regulation of transcription by RNA polymerase II RNA splicing cytoplasm; intracellular non-membrane-... |
chromatin remodeling positive regulation of histone acetylation positive regulation of transcription by RNA polymerase I positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase III regulation of double-strand break repair regulation of double-strand break repair ... | B-WICH complex; contractile fiber; nucleolus; nucleoplasm; nucleus | DNA binding histone binding RNA binding | Homo sapiens | 3D-structure Acetylation ADP-ribosylation Alternative splicing Chromatin regulator Chromosomal rearrangement Direct protein sequencing DNA-binding Nucleus Phosphoprotein Proto-oncogene Reference proteome | MSASAPAAEG | MSASAPAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKVERLTMQVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPP... | chromatin remodeling positive regulation of histone acetylation positive regulation of transcription by RNA polymerase I positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase III regulation of double-strand break repair regulation of double-strand break repair ... |
cellular detoxification of cadmium ion cellular response to cadmium ion glutathione biosynthetic process phytochelatin biosynthetic process phytochelatin-metal complex formation | cytosol; glutathione synthase complex | ATP binding glutathione binding glutathione synthase activity magnesium ion binding protein homodimerization activity | Schizosaccharomyces pombe | ATP-binding Direct protein sequencing Glutathione biosynthesis Ligase Magnesium Metal-binding Nucleotide-binding Phosphoprotein Reference proteome | MEIEKYTPEQ | MEIEKYTPEQIEELGKGARDFAFAHGVVFTELSVSKEGRNIATQIPITLFPSVIPHGAFVEAVSVQKAYNKLYAKIANDYEFLRLHLQSITKYDEFMNKLWNLYQKHREAVAHLKENQFQPLSLGVFRSDYMVHQDDSFIGCKQVEFNTISVSFGGVSKAVSNLHAYCSQSGLYRKPLTTNYLTVNTSVSGICTGISNAVDAYRDYVKNITSKMNIASDNTKPIVLFVVKGGERNITDQRTLEYELLNRFHVISKRIDIAELNSLIHDKSSNKLYMKTSFTTYEVAVVYYRVGYALDDYPSQEAWDMRLTIENTLAIKCP... | cellular detoxification of cadmium ion cellular response to cadmium ion glutathione biosynthetic process phytochelatin biosynthetic process phytochelatin-metal complex formation cytosol; glutathione synthase complex ATP binding glutathione binding glutathione synthase activity magnesium ion binding protein homodimeriza... |
actin cytoskeleton organization cytogamy negative regulation of protein kinase C signaling negative regulation of Rho protein signal transduction regulation of cell wall (1->3)-beta-D-glucan biosynthetic process regulation of fungal-type cell wall organization signal transduction sporulation resulting in formation of a... | cellular bud neck; cellular bud tip; cytoplasm; incipient cellular bud site; mating projection tip; mitochondrion; site of polarized growth | GTPase activator activity metal ion binding | Saccharomyces cerevisiae | Acetylation Cytoplasm GTPase activation LIM domain Metal-binding Phosphoprotein Reference proteome Repeat Sporulation Zinc | MIQNSAGYRS | MIQNSAGYRSLNTASPMTVQVKNQKKICARCNKLVIPDSQRTKTTLKALGKYYHESCFTCQDCQKPLKPKYFPYQVDKTSESILLCQYDYFRRHNLLCHVCDTPLRGLYYTAFGYRYDEEHFSCTICATPCGVKKCFMYGNQLYCKYHFLKYFSKRCKGCEFPISDQYIEFPKGEEIHCWHPECYGIHKYWHVNLAAETVGLQYLPKLEYNPNSGDKDINPTAYELDKQMQAFNFILSKTWSVLYRFEEEAASCISDMFQYLTSNDQLKGIESTGLLVLKIDCLFRGLDTLNLSTNKSMPVNSDQECIENNAMAASKYSK... | actin cytoskeleton organization cytogamy negative regulation of protein kinase C signaling negative regulation of Rho protein signal transduction regulation of cell wall (1->3)-beta-D-glucan biosynthetic process regulation of fungal-type cell wall organization signal transduction sporulation resulting in formation of a... |
cytoplasmic translation negative regulation of autophagy negative regulation of microtubule depolymerization | cytoplasm; cytoplasmic stress granule; cytosol; microtubule; mitochondrion | calcium ion binding | Saccharomyces cerevisiae | Cytoplasm Cytoskeleton Direct protein sequencing Microtubule Mitochondrion Phosphoprotein Protein biosynthesis Reference proteome | MIIYKDIFSN | MIIYKDIFSNDELLSDAYDAKLVDDVIYEADCAMVNVGGDNIDIGANPSAEGGDDDVEEGAEMVNNVVHSFRLQQTAFDKKSFLTYIKGYMKAVKAKLQETNPEEVPKFEKGAQTYVKKVIGSFKDWEFFTGESMDPDAMVVMLNYREDGTTPFVAIWKHGIVEEKI | cytoplasmic translation negative regulation of autophagy negative regulation of microtubule depolymerization cytoplasm; cytoplasmic stress granule; cytosol; microtubule; mitochondrion calcium ion binding Saccharomyces cerevisiae Cytoplasm Cytoskeleton Direct protein sequencing Microtubule Mitochondrion Phosphoprotein ... |
canonical NF-kappaB signal transduction cell redox homeostasis erythrocyte homeostasis fibroblast proliferation hydrogen peroxide catabolic process leukocyte activation natural killer cell activation natural killer cell mediated cytotoxicity regulation of non-canonical NF-kappaB signal transduction regulation of stress... | cytoplasm; cytosol; euchromatin; mitochondrial matrix; mitochondrion; myelin sheath; nucleus; peroxisomal matrix | heme binding identical protein binding peroxidase activity peroxiredoxin activity thioredoxin peroxidase activity | Mus musculus | Acetylation Antioxidant Cytoplasm Direct protein sequencing Disulfide bond Isopeptide bond Oxidoreductase Peroxidase Phosphoprotein Redox-active center Reference proteome Ubl conjugation | MSSGNAKIGY | MSSGNAKIGYPAPNFKATAVMPDGQFKDISLSEYKGKYVVFFFYPLDFTFVCPTEIIAFSDRADEFKKLNCQVIGASVDSHFCHLAWINTPKKQGGLGPMNIPLISDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITINDLPVGRSVDEIIRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVNKSKEYFSKQK | canonical NF-kappaB signal transduction cell redox homeostasis erythrocyte homeostasis fibroblast proliferation hydrogen peroxide catabolic process leukocyte activation natural killer cell activation natural killer cell mediated cytotoxicity regulation of non-canonical NF-kappaB signal transduction regulation of stress... |
cell redox homeostasis cellular response to oxidative stress defense response to tumor cell extrinsic apoptotic signaling pathway hydrogen peroxide catabolic process hydrogen peroxide metabolic process leukocyte activation negative regulation of extrinsic apoptotic signaling pathway negative regulation of extrinsic apo... | cytosol | antioxidant activity thioredoxin peroxidase activity | Rattus norvegicus | Acetylation Antioxidant Cytoplasm Direct protein sequencing Disulfide bond Oxidoreductase Peroxidase Phosphoprotein Redox-active center Reference proteome | MASGNAHIGK | MASGNAHIGKPAPDFTGTAVVDGAFKEIKLSDYRGKYVVLFFYPLDFTFVCPTEIIAFSDHAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTKSLSQNYGVLKNDEGIAYRGLFIIDAKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPGSDTIKPNVDDSKEYFSKHN | cell redox homeostasis cellular response to oxidative stress defense response to tumor cell extrinsic apoptotic signaling pathway hydrogen peroxide catabolic process hydrogen peroxide metabolic process leukocyte activation negative regulation of extrinsic apoptotic signaling pathway negative regulation of extrinsic apo... |
cell redox homeostasis cellular response to reactive oxygen species hydrogen peroxide catabolic process maternal placenta development mitochondrion organization myeloid cell differentiation negative regulation of apoptotic process positive regulation of cell population proliferation regulation of mitochondrial membrane... | cytosol; early endosome; mitochondrial matrix; mitochondrion; nucleoplasm; plasma membrane; protein-containing complex | cysteine-type endopeptidase inhibitor activity involved in apoptotic process identical protein binding protein kinase binding thioredoxin peroxidase activity | Bos taurus | 3D-structure Acetylation Antioxidant Cytoplasm Direct protein sequencing Disulfide bond Endosome Lipoprotein Mitochondrion Oxidoreductase Palmitate Peroxidase Phosphoprotein Redox-active center Reference proteome Transit peptide | MAATAGRLFR | MAATAGRLFRASLIRHVSAIPWGISASAALRPAASRRMCLTNALWSGSDQAKFAFSTSSSYHAPAVTQHAPYFKGTAVVSGEFKEISLDDFKGKYLVLFFYPLDFTFVCPTEIIAFSDKASEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGPGLALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQFVEAHGEVCPANWTPESPTIKPHPTASREYFEKVNQ | cell redox homeostasis cellular response to reactive oxygen species hydrogen peroxide catabolic process maternal placenta development mitochondrion organization myeloid cell differentiation negative regulation of apoptotic process positive regulation of cell population proliferation regulation of mitochondrial membrane... |
asymmetric neuroblast division cartilage condensation cartilage development cell fate commitment cellular response to transforming growth factor beta stimulus central nervous system neuron differentiation chondrocyte differentiation in utero embryonic development negative regulation of DNA-templated transcription oligo... | nucleus; transcription regulator complex | cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding transcription cis-regulatory region binding | Mus musculus | 3D-structure Activator Alternative splicing Coiled coil Differentiation DNA-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MLTDPDLPQE | MLTDPDLPQEFERMSSKRPASPYGETDGEVAMVTSRQKVEEEESERLPAFHLPLHVSFPNKPHSEEFQPVSLLTQETCGPRTPTVQHNTMEVDGNKVMSSLSPYNSSTSPQKAEEGGRQSGESVSSAALGTPERRKGSLADVVDTLKQRKMEELIKNEPEDTPSIEKLLSKDWKDKLLAMGSGNFGEIKGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQIARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAAQQGFLLPPGFSYKAGCSDPYPVQLIP... | asymmetric neuroblast division cartilage condensation cartilage development cell fate commitment cellular response to transforming growth factor beta stimulus central nervous system neuron differentiation chondrocyte differentiation in utero embryonic development negative regulation of DNA-templated transcription oligo... |
asymmetric neuroblast division cartilage condensation cartilage development cell fate commitment cellular response to transforming growth factor beta stimulus chondrocyte differentiation positive regulation of cartilage development positive regulation of chondrocyte differentiation positive regulation of mesenchymal st... | chromatin; nucleus | DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding transcription cis-regulatory region binding | Homo sapiens | Activator Alternative splicing Coiled coil Differentiation DNA-binding Intellectual disability Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MLTDPDLPQE | MLTDPDLPQEFERMSSKRPASPYGEADGEVAMVTSRQKVEEEESDGLPAFHLPLHVSFPNKPHSEEFQPVSLLTQETCGHRTPTSQHNTMEVDGNKVMSSFAPHNSSTSPQKAEEGGRQSGESLSSTALGTPERRKGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAMGSGNFGEIKGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQIARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAAQQGFLLPPGFSYKAGCSDPYPVQLIP... | asymmetric neuroblast division cartilage condensation cartilage development cell fate commitment cellular response to transforming growth factor beta stimulus chondrocyte differentiation positive regulation of cartilage development positive regulation of chondrocyte differentiation positive regulation of mesenchymal st... |
brain development cartilage condensation cartilage development cell fate commitment cellular response to transforming growth factor beta stimulus central nervous system development chondrocyte differentiation muscle organ development negative regulation of cardiac muscle cell differentiation positive regulation of cart... | chromatin; cytoplasm; nucleoplasm; nucleus | DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity protein homodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding transcription cis-regulatory region binding | Homo sapiens | Activator Alternative splicing Autism spectrum disorder Coiled coil Cytoplasm Developmental protein Differentiation Disease variant DNA-binding Intellectual disability Isopeptide bond Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation Ubl conjugation | MSSKQATSPF | MSSKQATSPFACAADGEDAMTQDLTSREKEEGSDQHVASHLPLHPIMHNKPHSEELPTLVSTIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDREIMTSVTFGTPERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEIKGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQIARQQQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITYKPGDNYPVQFIPSTMAAAAASGL... | brain development cartilage condensation cartilage development cell fate commitment cellular response to transforming growth factor beta stimulus central nervous system development chondrocyte differentiation muscle organ development negative regulation of cardiac muscle cell differentiation positive regulation of cart... |
angiogenesis blood vessel endothelial cell migration cell maturation embryonic heart tube development endocardial cell differentiation endocardium formation establishment of endothelial barrier hair cycle process hair follicle development heart looping in utero embryonic development lymphangiogenesis lymphatic endothel... | chromatin; nucleus; transcription regulator complex | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding transcription cis-regulatory region binding | Homo sapiens | Activator Disease variant DNA-binding Hypotrichosis Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MQRSPPGYGA | MQRSPPGYGAQDDPPARRDCAWAPGHGAAADTRGLAAGPAALAAPAAPASPPSPQRSPPRSPEPGRYGLSPAGRGERQAADESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLGKAWKELNAAEKRPFVEEAERLRVQHLRDHPNYKYRPRRKKQARKARRLEPGLLLPGLAPPQPPPEPFPAASGSARAFRELPPLGAEFDGLGLPTPERSPLDGLEPGEAAFFPPPAAPEDCALRPFRAPYAPTELSRDPGGCYGAPLAEALRTAPPAAPLAGLYYGTLGTPGPYPGPLSPPPEAPPLESAEPLGPAADLWA... | angiogenesis blood vessel endothelial cell migration cell maturation embryonic heart tube development endocardial cell differentiation endocardium formation establishment of endothelial barrier hair cycle process hair follicle development heart looping in utero embryonic development lymphangiogenesis lymphatic endothel... |
termination of RNA polymerase III transcription transcription by RNA polymerase III transcription initiation at RNA polymerase III promoter tRNA transcription by RNA polymerase III | nucleoplasm; nucleus; RNA polymerase III complex | DNA binding DNA-directed 5'-3' RNA polymerase activity | Saccharomyces cerevisiae | 3D-structure DNA-directed RNA polymerase Nucleus Phosphoprotein Reference proteome Transcription | MFILSKIADL | MFILSKIADLVRIPPDQFHRDTISAITHQLNNKFANKIIPNVGLCITIYDLLTVEEGQLKPGDGSSYINVTFRAVVFKPFLGEIVTGWISKCTAEGIKVSLLGIFDDIFIPQNMLFEGCYYTPEESAWIWPMDEETKLYFDVNEKIRFRIEREVFVDVKPKSPKERELEERAQLENEIEGKNEETPQNEKPPAYALLGSCQTDGMGLVSWWE | termination of RNA polymerase III transcription transcription by RNA polymerase III transcription initiation at RNA polymerase III promoter tRNA transcription by RNA polymerase III nucleoplasm; nucleus; RNA polymerase III complex DNA binding DNA-directed 5'-3' RNA polymerase activity Saccharomyces cerevisiae 3D-struct... |
mRNA polyadenylation protein polyubiquitination protein ubiquitination termination of RNA polymerase II transcription, poly(A)-coupled ubiquitin-dependent protein catabolic process | cytosol; mRNA cleavage and polyadenylation specificity factor complex; nucleus | pre-mRNA binding ubiquitin protein ligase activity zinc ion binding | Saccharomyces cerevisiae | 3D-structure Metal-binding mRNA processing Nucleus Phosphoprotein Reference proteome Zinc Zinc-finger | MSSTIFYRFK | MSSTIFYRFKSQRNTSRILFDGTGLTVFDLKREIIQENKLGDGTDFQLKIYNPDTEEEYDDDAFVIPRSTSVIVKRSPAIKSFSVHSRLKGNVGAAALGNATRYVTGRPRVLQKRQHTATTTANVSGTTEEERIASMFATQENQWEQTQEEMSAATPVFFKSQTNKNSAQENEGPPPPGYMCYRCGGRDHWIKNCPTNSDPNFEGKRIRRTTGIPKKFLKSIEIDPETMTPEEMAQRKIMITDEGKFVVQVEDKQSWEDYQRKRENRQIDGDETIWRKGHFKDLPDDLKCPLTGGLLRQPVKTSKCCNIDFSKEALENAL... | mRNA polyadenylation protein polyubiquitination protein ubiquitination termination of RNA polymerase II transcription, poly(A)-coupled ubiquitin-dependent protein catabolic process cytosol; mRNA cleavage and polyadenylation specificity factor complex; nucleus pre-mRNA binding ubiquitin protein ligase activity zinc ion ... |
DNA damage response protein ubiquitination regulation of protein complex stability telomere maintenance transcription-coupled nucleotide-excision repair ubiquitin-dependent protein catabolic process | chromatin; chromosome, telomeric region; cytoplasm; nucleus | DNA binding ubiquitin binding | Saccharomyces cerevisiae | Chromosome Cytoplasm DNA damage DNA repair DNA-binding Nucleus Phosphoprotein Reference proteome Telomere Ubl conjugation Ubl conjugation pathway | MSTQFRKSNH | MSTQFRKSNHNSHSSKKLNPALKSKIDTLTELFPDWTSDDLIDIVQEYDDLETIIDKITSGAVTRWDEVKKPAKKEKYEKKEQQHSYVPQQHLPNPEDDITYKSSNNSNSFTSTKHNSSNNYTQARNKKKVQTPRAHTTGKHVNLDKGKHVPSKPVSNTTSWAAAVSVDTKHDVPQDSNDNNNEELEAQGQQAQEKNQEKEQEEQQQQEGHNNKEEHKQIEQPSLSSKKTTSRTSASQPKKMSWAAIATPKPKAVKKTESPLENVAELKKEISDIKKDDQKSEASEEKVNEQETSAQEQEEETAEPSEENEDRVPEVDGE... | DNA damage response protein ubiquitination regulation of protein complex stability telomere maintenance transcription-coupled nucleotide-excision repair ubiquitin-dependent protein catabolic process chromatin; chromosome, telomeric region; cytoplasm; nucleus DNA binding ubiquitin binding Saccharomyces cerevisiae Chrom... |
adaptive immune response antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II chaperone cofactor-dependent protein refolding MHC class II protein complex assembly peptide antigen assembly with MHC class II protein complex positive regulation of immune res... | intracellular membrane-bounded organelle; late endosome membrane; lysosomal membrane; MHC class II protein complex | MHC class II protein complex binding peptide antigen binding | Mus musculus | Adaptive immunity Disulfide bond Endosome Glycoprotein Immunity Lysosome Membrane MHC II Reference proteome Signal Transmembrane Transmembrane helix | MAALWLLLLV | MAALWLLLLVLSLHCMGAGGFVAHVESTCVLDDAGTPQDFTYCVSFNKDLLACWDPIVGKIVPCEFGVLYPLAENFSRILNKEESLLQRLQNGLPDCASHTQPFWNALTHRTRPPSVRVAQTTPFNTREPVMLACYVWGFYPADVTITWMKNGQLVPSHSNKEKTAQPNGDWTYQTVSYLALTPSYGDVYTCVVQHSGTSEPIRGDWTPGLSPIQTVKVSVSAATLGLGFIIFCVGFFRWRKSHSSSYTPLSGSTYPEGRH | adaptive immune response antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II chaperone cofactor-dependent protein refolding MHC class II protein complex assembly peptide antigen assembly with MHC class II protein complex positive regulation of immune res... |
cellular response to calcium ion starvation cellular response to starvation negative regulation of mitochondrial depolarization | cytoplasm; extracellular space; protein-containing complex | DNA binding enterobactin binding fatty acid binding metal ion binding pyridoxal phosphate binding toxic substance binding | Equus caballus | 3D-structure Allergen Calcium Cleavage on pair of basic residues Copper Disulfide bond Lipid-binding Metal-binding Methylation Phosphoprotein Reference proteome Repeat Secreted Signal Zinc | MKWVTFVSLL | MKWVTFVSLLFLFSSAYSRGVLRRDTHKSEIAHRFNDLGEKHFKGLVLVAFSQYLQQCPFEDHVKLVNEVTEFAKKCAADESAENCDKSLHTLFGDKLCTVATLRATYGELADCCEKQEPERNECFLTHKDDHPNLPKLKPEPDAQCAAFQEDPDKFLGKYLYEVARRHPYFYGPELLFHAEEYKADFTECCPADDKLACLIPKLDALKERILLSSAKERLKCSSFQNFGERAVKAWSVARLSQKFPKADFAEVSKIVTDLTKVHKECCHGDLLECADDRADLAKYICEHQDSISGKLKACCDKPLLQKSHCIAEVKEDD... | cellular response to calcium ion starvation cellular response to starvation negative regulation of mitochondrial depolarization cytoplasm; extracellular space; protein-containing complex DNA binding enterobactin binding fatty acid binding metal ion binding pyridoxal phosphate binding toxic substance binding Equus cabal... |
proteolysis regulation of catalytic activity self proteolysis | cytoplasm; cytosol; plasma membrane | calcium ion binding calcium-dependent cysteine-type endopeptidase activity | Sus scrofa | Autocatalytic cleavage Calcium Cell membrane Cytoplasm Hydrolase Membrane Metal-binding Phosphoprotein Protease Reference proteome Repeat Thiol protease | MAEEVITPVY | MAEEVITPVYCTGVSAQVQKLRAKELGLGRHENAIKYLGQDYEQLRAHCLQSGSLFRDEAFPPVPQSLGFKELGPNSSKTYGVKWKRPTELFSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNDTLLHRVVPHGQSFQNGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSALLEKAYAKVNGSYEALSGGSTSEGFEDFTGGVTEWYELRKAPSDLYSIILKALERGSLLGCSIDISSVLDMEAVTFKKLVKGHAYSVTGAKQVNYQGQMVNLIRMRNPWGEVEWTGAWSDGSSEWNGVDPY... | proteolysis regulation of catalytic activity self proteolysis cytoplasm; cytosol; plasma membrane calcium ion binding calcium-dependent cysteine-type endopeptidase activity Sus scrofa Autocatalytic cleavage Calcium Cell membrane Cytoplasm Hydrolase Membrane Metal-binding Phosphoprotein Protease Reference proteome Repea... |
nucleobase-containing small molecule interconversion positive regulation of membrane potential | cytosol; extracellular exosome; nucleus | glutathione disulfide oxidoreductase activity sodium channel regulator activity | Homo sapiens | 3D-structure Acetylation Cytoplasm Direct protein sequencing Disulfide bond Electron transport Redox-active center Reference proteome Transport | MAQEFVNCKI | MAQEFVNCKIQPGKVVVFIKPTCPYCRRAQEILSQLPIKQGLLEFVDITATNHTNEIQDYLQQLTGARTVPRVFIGKDCIGGCSDLVSLQQSGELLTRLKQIGALQ | nucleobase-containing small molecule interconversion positive regulation of membrane potential cytosol; extracellular exosome; nucleus glutathione disulfide oxidoreductase activity sodium channel regulator activity Homo sapiens 3D-structure Acetylation Cytoplasm Direct protein sequencing Disulfide bond Electron transpo... |
chromosome segregation female meiosis chromosome segregation meiotic spindle assembly checkpoint signaling mitotic spindle assembly checkpoint signaling phosphorylation protein localization to chromosome protein localization to kinetochore protein localization to meiotic spindle midzone | cytoplasm; kinetochore; nucleus | ATP binding identical protein binding kinetochore binding protein serine kinase activity protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity | Mus musculus | Acetylation Alternative splicing ATP-binding Kinase Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase Tyrosine-protein kinase | MEAEELIGSS | MEAEELIGSSVTIDSIMSKMRDIKNKINEDCTDELSLSKICADHTETVNQIMRVGNTPENWLNFLLKLEKNSSPLNDDLLNKLIGRYSQAIEVLPPDKYGQNESFARIQVRLAELKAIQEPDDARDYFQMARENCKKFAFVHVSFAQFELSQGNLKKSEQLLHKAVETGAVPLQMLETAMRNLHLQKKQLLPEEDKKSVSASTVLSAQEPFSSSLGNVQNRSISCESRGQAGAARVLYGENLPPQDAEVRHQNPFKQTHAAKRSCPFGRVPVNLLNSPDFYVKTDSSAVTQLTTRLALSSVPLPYVTCLLHLQLLALAGL... | chromosome segregation female meiosis chromosome segregation meiotic spindle assembly checkpoint signaling mitotic spindle assembly checkpoint signaling phosphorylation protein localization to chromosome protein localization to kinetochore protein localization to meiotic spindle midzone cytoplasm; kinetochore; nucleus ... |
circadian rhythm defense response to tumor cell defense response to virus granzyme-mediated programmed cell death signaling pathway immune response to tumor cell immunological synapse formation killing of cells of another organism positive regulation of killing of cells of another organism protein homooligomerization p... | cytolytic granule; cytoplasmic vesicle; endosome lumen; extracellular space; immunological synapse; membrane; plasma membrane | calcium ion binding identical protein binding pore-forming activity wide pore channel activity | Rattus norvegicus | Calcium Cell membrane Cytolysis Disulfide bond EGF-like domain Endosome Glycoprotein Lysosome Membrane Metal-binding Reference proteome Secreted Signal Transmembrane Transmembrane beta strand | MAAYLFLLGL | MAAYLFLLGLFLLLPRPVPAPCYTATRSECKQNHKFVPGVWAAGEGVDVTTLRRSSSFPVNTGKFLRPDRTCTLCKNALMNDGIQRLPVAIAHWRPHGSHCQRNVATTKVSSTEGVAREAAANINNDWRAGLDVNPKPEANVHVSVAGSHSKIANFAAEKAHQDQYNFNTDTVECRMYSFRLAQKPPLHPDFRKALKNLPHNFNSSTEHAYRRLISSYGTHFITAVDLGGRVSVLTALRTCQLTLDGLTADEVGDCLSVEAQVSIGAQASVSSEYKACEEKKKQHKIATSFHQTYRERHVEVLGGPLDSSNDLLFGNQAT... | circadian rhythm defense response to tumor cell defense response to virus granzyme-mediated programmed cell death signaling pathway immune response to tumor cell immunological synapse formation killing of cells of another organism positive regulation of killing of cells of another organism protein homooligomerization p... |
regulation of transcription by RNA polymerase II retrotransposon silencing | nucleus | DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding zinc ion binding | Homo sapiens | 3D-structure Alternative splicing DNA-binding Metal-binding Nucleus Reference proteome Repeat Repressor Transcription Transcription regulation Zinc Zinc-finger | MGPLQFRDVA | MGPLQFRDVAIEFSLEEWHCLDTAQRNLYRNVMLENYSNLVFLGIVVSKPDLIAHLEQGKKPLTMKRHEMVANPSVICSHFAQDLWPEQNIKDSFQKVILRRYEKRGHGNLQLIKRCESVDECKVHTGGYNGLNQCSTTTQSKVFQCDKYGKVFHKFSNSNRHNIRHTEKKPFKCIECGKAFNQFSTLITHKKIHTGEKPYICEECGKAFKYSSALNTHKRIHTGEKPYKCDKCDKAFIASSTLSKHEIIHTGKKPYKCEECGKAFNQSSTLTKHKKIHTGEKPYKCEECGKAFNQSSTLTKHKKIHTGEKPYVCEECGK... | regulation of transcription by RNA polymerase II retrotransposon silencing nucleus DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-spe... |
CDP-choline pathway cellular response to glucose starvation lipid droplet disassembly lipid metabolic process lipid transport phosphatidylcholine biosynthetic process phosphatidylethanolamine biosynthetic process phosphorylation | cytoplasm; cytosol; lipid droplet | ATP binding choline kinase activity cholinesterase activity ethanolamine kinase activity protein homodimerization activity protein tyrosine kinase activity | Homo sapiens | 3D-structure Acetylation Alternative splicing ATP-binding Cytoplasm Disease variant Epilepsy Intellectual disability Kinase Lipid biosynthesis Lipid droplet Lipid metabolism Nucleotide-binding Phospholipid biosynthesis Phospholipid metabolism Phosphoprotein Reference proteome Transferase Tyrosine-protein kinase | MKTKFCTGGE | MKTKFCTGGEAEPSPLGLLLSCGSGSAAPAPGVGQQRDAASDLESKQLGGQQPPLALPPPPPLPLPLPLPQPPPPQPPADEQPEPRTRRRAYLWCKEFLPGAWRGLREDEFHISVIRGGLSNMLFQCSLPDTTATLGDEPRKVLLRLYGAILQMRSCNKEGSEQAQKENEFQGAEAMVLESVMFAILAERSLGPKLYGIFPQGRLEQFIPSRRLDTEELSLPDISAEIAEKMATFHGMKMPFNKEPKWLFGTMEKYLKEVLRIKFTEESRIKKLHKLLSYNLPLELENLRSLLESTPSPVVFCHNDCQEGNILLLEGREN... | CDP-choline pathway cellular response to glucose starvation lipid droplet disassembly lipid metabolic process lipid transport phosphatidylcholine biosynthetic process phosphatidylethanolamine biosynthetic process phosphorylation cytoplasm; cytosol; lipid droplet ATP binding choline kinase activity cholinesterase activi... |
collagen and cuticulin-based cuticle development cuticle development involved in collagen and cuticulin-based cuticle molting cycle locomotion post-embryonic body morphogenesis regulation of gene expression | collagen trimer; extracellular region | structural constituent of collagen and cuticulin-based cuticle structural constituent of cuticle | Caenorhabditis elegans | Alternative splicing Collagen Cuticle Disulfide bond Reference proteome Repeat Signal | MKNNAKEDYR | MKNNAKEDYRTFSLTTNYSRQMIYRCVTGLQIGFSLFSFIIVCVALPIMYNHVQNTITYVDREMAYCEVRFLYFYCIKFFSTLQRSNDEAALELQYGKMRMTGNRTARGAYGSGASHGFRPTAYGDEITGAPLETECPGCCIPGPPGPRGSSGTPGKPGLPGNAGKPGMPGTTPNQTCPLNQVREPPPCRPCPKGPPGIKGWPGFPGDVGPPGPPGLKGIDGEDGAPGETGPTGPPGYRGGPGAPGDKGPTPEGDLKEGPPGDEGPPGPIGAPGMPGLPGRNGLTGGQGERGWPGVSGESGEPGYPGPEGPMGGQGPPGE... | collagen and cuticulin-based cuticle development cuticle development involved in collagen and cuticulin-based cuticle molting cycle locomotion post-embryonic body morphogenesis regulation of gene expression collagen trimer; extracellular region structural constituent of collagen and cuticulin-based cuticle structural c... |
neural retina development neuron migration neuron projection development neuron projection morphogenesis positive regulation of filopodium assembly regulation of synapse organization response to bacterium stem cell differentiation synapse assembly | axonal growth cone; dendritic spine; filopodium; glutamatergic synapse; neuron projection; neuronal cell body; parallel fiber to Purkinje cell synapse; plasma membrane; presynapse; presynaptic active zone membrane | calcium channel activity | Mus musculus | Acetylation Cell membrane Cell projection Direct protein sequencing Disulfide bond Glycoprotein Lipoprotein Membrane Neurogenesis Palmitate Phosphoprotein Reference proteome Synapse Transmembrane Transmembrane helix | MEENMEEGQT | MEENMEEGQTQKGCFECCIKCLGGIPYASLIATILLYAGVALFCGCGHEALSGTVNILQTYFELARTAGDTLDVFTMIDIFKYVIYGIAAAFFVYGILLMVEGFFTTGAIKDLYGDFKITTCGRCVSAWFIMLTYLFMLAWLGVTAFTSLPVYMYFNVWTICRNTTLVEGANLCLDLRQFGIVTIGEEKKICTASENFLRMCESTELNMTFHLFIVALAGAGAAVIAMVHYLMVLSANWAYVKDACRMQKYEDIKSKEEQELHDIHSTRSKERLNAYT | neural retina development neuron migration neuron projection development neuron projection morphogenesis positive regulation of filopodium assembly regulation of synapse organization response to bacterium stem cell differentiation synapse assembly axonal growth cone; dendritic spine; filopodium; glutamatergic synapse; ... |
axon development central nervous system myelination extracellular matrix assembly negative regulation of protein localization to cell surface negative regulation of serotonin uptake ossification positive regulation of bone mineralization protein transport regulation of actin cytoskeleton organization regulation of foca... | membrane raft; myelin sheath; plasma membrane | structural constituent of myelin sheath | Mus musculus | Alternative splicing Cell membrane Direct protein sequencing Glycoprotein Membrane Osteogenesis Phosphoprotein Protein transport Reference proteome Transmembrane Transmembrane helix Transport | MKPAMETAAE | MKPAMETAAEENTEQSQERKVNSRAEMEIGRYHWMYPGSKNHQYRPVPNLGDRAGPLSSPGCFECCIKCLGGVPYASLVATILCFSGVALFCGCGHVALAGTVAILEQHFSTNTSDHALLSEVIQLMQYVIYGIASFFFLYGIILLAEGFYTTSAVKELHGEFKTTACGRCISGMFVFLTYVLGVAWLGVFGFSAVPVFMFYNIWSTCEVIKSPQSNGTSGVEQICVDVRQYGIIPWNAFPGKICGSALENICNTNEFYMSYHLFIVACAGAGATVIALIHFLMILSSNWAYLKDASKMQAYQDIKAKEEQELQDIQSRS... | axon development central nervous system myelination extracellular matrix assembly negative regulation of protein localization to cell surface negative regulation of serotonin uptake ossification positive regulation of bone mineralization protein transport regulation of actin cytoskeleton organization regulation of foca... |
cellular response to transforming growth factor beta stimulus dephosphorylation N-terminal protein myristoylation negative regulation of BMP signaling pathway negative regulation of canonical NF-kappaB signal transduction negative regulation of non-canonical NF-kappaB signal transduction negative regulation of transcri... | cytosol; membrane; nucleoplasm; nucleus; plasma membrane | calmodulin-dependent protein phosphatase activity magnesium ion binding manganese ion binding myosin phosphatase activity protein serine/threonine phosphatase activity R-SMAD binding | Homo sapiens | 3D-structure Alternative splicing Cytoplasm Hydrolase Lipoprotein Magnesium Manganese Membrane Metal-binding Myristate Nucleus Phosphoprotein Protein phosphatase Reference proteome | MGAFLDKPKM | MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYDGHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAPKVSPEAVKKEAELDKYLECRVEEII... | cellular response to transforming growth factor beta stimulus dephosphorylation N-terminal protein myristoylation negative regulation of BMP signaling pathway negative regulation of canonical NF-kappaB signal transduction negative regulation of non-canonical NF-kappaB signal transduction negative regulation of transcri... |
N-terminal protein myristoylation negative regulation of canonical NF-kappaB signal transduction negative regulation of non-canonical NF-kappaB signal transduction positive regulation of canonical NF-kappaB signal transduction protein dephosphorylation | cytosol; membrane; nucleus | magnesium ion binding manganese ion binding myosin phosphatase activity phosphoprotein phosphatase activity R-SMAD binding | Oryctolagus cuniculus | Cytoplasm Hydrolase Lipoprotein Magnesium Manganese Membrane Metal-binding Myristate Nucleus Phosphoprotein Protein phosphatase Reference proteome | MGAFLDKPKM | MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLETWSFFAVYDGHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAPKVSPEAVKKEAELDKYLECRVEEIL... | N-terminal protein myristoylation negative regulation of canonical NF-kappaB signal transduction negative regulation of non-canonical NF-kappaB signal transduction positive regulation of canonical NF-kappaB signal transduction protein dephosphorylation cytosol; membrane; nucleus magnesium ion binding manganese ion bind... |
N-terminal protein myristoylation negative regulation of canonical NF-kappaB signal transduction negative regulation of defense response to virus negative regulation of interferon-beta production negative regulation of non-canonical NF-kappaB signal transduction positive regulation of canonical Wnt signaling pathway pr... | cytosol; membrane; nucleus | magnesium ion binding manganese ion binding myosin phosphatase activity protein serine/threonine phosphatase activity | Rattus norvegicus | Alternative splicing Cytoplasm Hydrolase Isopeptide bond Lipoprotein Magnesium Manganese Membrane Metal-binding Myristate Phosphoprotein Protein phosphatase Reference proteome Ubl conjugation | MGAFLDKPKT | MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYDGHAGSRVANYCSTHLLEHITTNEDFRAADKSGFALEPSVENVKTGIRTGFLKIDEYMRNFSDLRNGMDRSGSTAVGVMISPTHIYFINCGDSRAVLCRNGQVCFSTQDHKPCNPMEKERIQNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFVVLACDGIWDVMSNEELCEFVNSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFANAPKVSDEAVKRDLELDKHLESRV... | N-terminal protein myristoylation negative regulation of canonical NF-kappaB signal transduction negative regulation of defense response to virus negative regulation of interferon-beta production negative regulation of non-canonical NF-kappaB signal transduction positive regulation of canonical Wnt signaling pathway pr... |
dephosphorylation | mitochondrion | -phosphatase activity phosphatase regulator activity calcium ion binding magnesium ion binding | Bos taurus | 3D-structure Acetylation Calcium Direct protein sequencing Hydrolase Magnesium Metal-binding Mitochondrion Protein phosphatase Reference proteome Transit peptide | MPAPTQLFFP | MPAPTQLFFPLIRNCELSRIYGTACYCHHKHLCCSPPYIPQSRPRYTPHPAYATFYRPKESWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYSFKVPEFDGKNVSSVLGFDSNQLPANAPIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLNTGESTDIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNER... | dephosphorylation mitochondrion -phosphatase activity phosphatase regulator activity calcium ion binding magnesium ion binding Bos taurus 3D-structure Acetylation Calcium Direct protein sequencing Hydrolase Magnesium Metal-binding Mitochondrion Protein phosphatase Reference proteome Transit peptide MPAPTQLFFP MPAPTQLF... |
chromatin remodeling DNA repair negative regulation of heterochromatin formation regulation of DNA-templated transcription regulation of silent mating-type cassette heterochromatin formation snRNA transcription sporulation resulting in formation of a cellular spore | chromatin; nucleus; Swr1 complex | chromatin binding core promoter sequence-specific DNA binding lysine-acetylated histone binding TFIID-class transcription factor complex binding | Saccharomyces cerevisiae | Bromodomain Coiled coil DNA damage DNA repair Nucleus Phosphoprotein Reference proteome Repeat Sporulation Transcription Transcription regulation | MTDITPVQND | MTDITPVQNDVDVNGNNVNDDVSSNLKRPIDQGDPSNGLAEEENPANNQLHLKKARLDGDALTSSPAGLAENGIEGATLAANGENGYNATGSGAEDEQQGLKKEEGGQGTKQEDLDENSKQELPMEVPKEPAPAPPPEPDMNNLPQNPIPKHQQKHALLAIKAVKRLKDARPFLQPVDPVKLDIPFYFNYIKRPMDLSTIERKLNVGAYEVPEQITEDFNLMVNNSIKFNGPNAGISQMARNIQASFEKHMLNMPAKDAPPVIAKGRRSSAQEDAPIVIRRAQTHNGRPKRTIHPPKSKDIYPYESKKPKSKRLQQAMKF... | chromatin remodeling DNA repair negative regulation of heterochromatin formation regulation of DNA-templated transcription regulation of silent mating-type cassette heterochromatin formation snRNA transcription sporulation resulting in formation of a cellular spore chromatin; nucleus; Swr1 complex chromatin binding cor... |
protein secretion protein secretion by the type II secretion system | cell outer membrane; type II protein secretion system complex | identical protein binding | Pseudomonas aeruginosa | 3D-structure Cell outer membrane Membrane Protein transport Reference proteome Signal Transmembrane Transmembrane beta strand Transport | MSQPLLRALF | MSQPLLRALFAPSSRSYVPAVLLSLALGIQAAHAENSGGNAFVPAGNQQEAHWTINLKDADIREFIDQISEITGETFVVDPRVKGQVSVVSKAQLSLSEVYQLFLSVMSTHGFTVVAQGDQARIVPNAEAKTEAGGGQSAPDRLETRVIQVQQSPVSELIPLIRPLVPQYGHLAAVPSANALIISDRSANIARIEDVIRQLDQKGSHDYSVINLRYGWVMDAAEVLNNAMSRGQAKGAAGAQVIADARTNRLIILGPPQARAKLVQLAQSLDTPTARSANTRVIRLRHNDAKTLAETLGQISEGMKNNGGQGGEQTGGGR... | protein secretion protein secretion by the type II secretion system cell outer membrane; type II protein secretion system complex identical protein binding Pseudomonas aeruginosa 3D-structure Cell outer membrane Membrane Protein transport Reference proteome Signal Transmembrane Transmembrane beta strand Transport MSQPL... |
cellular response to epidermal growth factor stimulus peptidyl-tyrosine dephosphorylation regulation of epidermal growth factor receptor signaling pathway tissue regeneration | cell projection; cytoplasm; cytosol; focal adhesion; nucleus; podosome | non-membrane spanning protein tyrosine phosphatase activity phosphoprotein phosphatase activity protein tyrosine phosphatase activity SH3 domain binding | Mus musculus | Acetylation Cell junction Cell projection Cytoplasm Hydrolase Phosphoprotein Protein phosphatase Reference proteome | MEQVEILRRF | MEQVEILRRFIQRVQAMKSPDHNGEDNFARDFMRLRRLSTKYRTEKIYPTATGEKEENVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCENEQARTDYFIRTLLLEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQLYEIHGAQKIADGNEITTGTM... | cellular response to epidermal growth factor stimulus peptidyl-tyrosine dephosphorylation regulation of epidermal growth factor receptor signaling pathway tissue regeneration cell projection; cytoplasm; cytosol; focal adhesion; nucleus; podosome non-membrane spanning protein tyrosine phosphatase activity phosphoprotein... |
granulocyte colony-stimulating factor signaling pathway immune response positive regulation of actin filament polymerization positive regulation of cell population proliferation positive regulation of myeloid cell differentiation positive regulation of peptidyl-tyrosine phosphorylation positive regulation of phosphatid... | extracellular space | cytokine activity enzyme binding granulocyte colony-stimulating factor receptor binding growth factor activity | Bos taurus | 3D-structure Cytokine Disulfide bond Glycoprotein Growth factor Reference proteome Secreted Signal | MKLMVLQLLL | MKLMVLQLLLWHSALWTVHEATPLGPARSLPQSFLLKCLEQVRKIQADGAELQERLCAAHKLCHPEELMLLRHSLGIPQAPLSSCSSQSLQLTSCLNQLHGGLFLYQGLLQALAGISPELAPTLDTLQLDVTDFATNIWLQMEDLGAAPAVQPTQGAMPTFTSAFQRRAGGVLVASQLHRFLELAYRGLRYLAEP | granulocyte colony-stimulating factor signaling pathway immune response positive regulation of actin filament polymerization positive regulation of cell population proliferation positive regulation of myeloid cell differentiation positive regulation of peptidyl-tyrosine phosphorylation positive regulation of phosphatid... |
fibrinolysis hemostasis proteolysis sporulation resulting in formation of a cellular spore | extracellular region | metal ion binding serine-type endopeptidase activity | Bacillus subtilis subsp. natto | 3D-structure Blood coagulation Calcium Direct protein sequencing Fibrinolysis Hemostasis Hydrolase Metal-binding Protease Secreted Serine protease Signal Sporulation Zymogen | MRSKKLWISL | MRSKKLWISLLFALTLIFTMAFSNMSAQAAGKSSTEKKYIVGFKQTMSAMSSAKKKDVISEKGGKVQKQFKYVNAAAATLDEKAVKELKKDPSVAYVEEDHIAHEYAQSVPYGISQIKAPALHSQGYTGSNVKVAVIDSGIDSSHPDLNVRGGASFVPSETNPYQDGSSHGTHVAGTIAALNNSIGVLGVAPSASLYAVKVLDSTGSGQYSWIINGIEWAISNNMDVINMSLGGPTGSTALKTVVDKAVSSGIVVAAAAGNEGSSGSTSTVGYPAKYPSTIAVGAVNSSNQRASFSSVGSELDVMAPGVSIQSTLPGGTY... | fibrinolysis hemostasis proteolysis sporulation resulting in formation of a cellular spore extracellular region metal ion binding serine-type endopeptidase activity Bacillus subtilis subsp. natto3D-structure Blood coagulation Calcium Direct protein sequencing Fibrinolysis Hemostasis Hydrolase Metal-binding Protease Sec... |
endocytosis exocytosis maintenance of cell polarity piecemeal microautophagy of the nucleus sterol biosynthetic process sterol transport | cellular bud neck; cytosol; fungal-type vacuole membrane; intracellular membrane-bounded organelle; membrane | lipid binding oxysterol binding sterol transfer activity sterol transporter activity | Saccharomyces cerevisiae | Lipid biosynthesis Lipid metabolism Membrane Phosphoprotein Reference proteome Steroid biosynthesis Steroid metabolism Sterol biosynthesis Sterol metabolism Vacuole | MSQHASSSSW | MSQHASSSSWTSFLKSISSFNGDLSSLSAPPFILSPTSLTEFSQYWAEHPALFLEPSLIDGENYKDHCPFDPNVESKEVAQMLAVVRWFISTLRSQYCSRSESMGSEKKPLNPFLGEVFVGKWKNDEHPEFGETVLLSEQVSHHPPMTAFSIFNEKNDVSVQGYNQIKTGFTKTLTLTVKPYGHVILKIKDETYLITTPPLHIEGILVASPFVELGGRSFIQSSNGMLCVIEFSGRGYFTGKKNSFKARIYRSPQEHSHKENALYLISGQWSGVSTIIKKDSQVSHQFYDSSETPTEHLLVKPIEEQHPLESRRAWKDVA... | endocytosis exocytosis maintenance of cell polarity piecemeal microautophagy of the nucleus sterol biosynthetic process sterol transport cellular bud neck; cytosol; fungal-type vacuole membrane; intracellular membrane-bounded organelle; membrane lipid binding oxysterol binding sterol transfer activity sterol transporte... |
endocytosis ER to Golgi ceramide transport exocytosis maintenance of cell polarity piecemeal microautophagy of the nucleus post-Golgi vesicle-mediated transport sphingolipid metabolic process sterol transport | cytoplasm; cytosol; Golgi membrane; intracellular membrane-bounded organelle; membrane | lipid binding oxysterol binding phosphatidic acid binding phosphatidylinositol-4,5-bisphosphate binding phosphatidylinositol-4-phosphate binding sterol transfer activity sterol transporter activity | Saccharomyces cerevisiae | 3D-structure Cytoplasm Golgi apparatus Lipid transport Lipid-binding Membrane Phosphoprotein Reference proteome Transport | MSQYASSSSW | MSQYASSSSWTSFLKSIASFNGDLSSLSAPPFILSPISLTEFSQYWAEHPELFLEPSFINDDNYKEHCLIDPEVESPELARMLAVTKWFISTLKSQYCSRNESLGSEKKPLNPFLGELFVGKWENKEHPEFGETVLLSEQVSHHPPVTAFSIFNDKNKVKLQGYNQIKASFTKSLMLTVKQFGHTMLDIKDESYLVTPPPLHIEGILVASPFVELEGKSYIQSSTGLLCVIEFSGRGYFSGKKNSFKARIYKDSKDSKDKEKALYTISGQWSGSSKIIKANKKEESRLFYDAARIPAEHLNVKPLEEQHPLESRKAWYDV... | endocytosis ER to Golgi ceramide transport exocytosis maintenance of cell polarity piecemeal microautophagy of the nucleus post-Golgi vesicle-mediated transport sphingolipid metabolic process sterol transport cytoplasm; cytosol; Golgi membrane; intracellular membrane-bounded organelle; membrane lipid binding oxysterol ... |
anterior neural tube closure axon regeneration cardiac neural crest cell migration involved in outflow tract morphogenesis cell adhesion cellular response to folic acid folic acid metabolic process folic acid transport fusion of sperm to egg plasma membrane involved in single fertilization heart looping neural crest ce... | apical plasma membrane; basolateral plasma membrane; brush border membrane; clathrin-coated vesicle; endosome; external side of plasma membrane; extracellular region; membrane; nucleus | folic acid binding folic acid receptor activity signaling receptor activity | Mus musculus | Cell membrane Cytoplasmic vesicle Disulfide bond Endosome Folate-binding Glycoprotein GPI-anchor Lipoprotein Membrane Receptor Reference proteome Secreted Signal Transport | MAHLMTVQLL | MAHLMTVQLLLLVMWMAECAQSRATRARTELLNVCMDAKHHKEKPGPEDNLHDQCSPWKTNSCCSTNTSQEAHKDISYLYRFNWNHCGTMTSECKRHFIQDTCLYECSPNLGPWIQQVDQSWRKERILDVPLCKEDCQQWWEDCQSSFTCKSNWHKGWNWSSGHNECPVGASCHPFTFYFPTSAALCEEIWSHSYKLSNYSRGSGRCIQMWFDPAQGNPNEEVARFYAEAMSGAGFHGTWPLLCSLSLVLLWVIS | anterior neural tube closure axon regeneration cardiac neural crest cell migration involved in outflow tract morphogenesis cell adhesion cellular response to folic acid folic acid metabolic process folic acid transport fusion of sperm to egg plasma membrane involved in single fertilization heart looping neural crest ce... |
cell adhesion signal transduction | extracellular exosome; extracellular matrix; extracellular region; extracellular space; insulin-like growth factor ternary complex | insulin-like growth factor binding | Homo sapiens | 3D-structure Alternative splicing Cell adhesion Direct protein sequencing Disease variant Glycoprotein Leucine-rich repeat Reference proteome Repeat Secreted Signal | MALRKGGLAL | MALRKGGLALALLLLSWVALGPRSLEGADPGTPGEAEGPACPAACVCSYDDDADELSVFCSSRNLTRLPDGVPGGTQALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQ... | cell adhesion signal transduction extracellular exosome; extracellular matrix; extracellular region; extracellular space; insulin-like growth factor ternary complex insulin-like growth factor binding Homo sapiens 3D-structure Alternative splicing Cell adhesion Direct protein sequencing Disease variant Glycoprotein Leuc... |
cell adhesion cellular response to dexamethasone stimulus cellular response to epidermal growth factor stimulus cellular response to growth hormone stimulus cellular response to interleukin-1 response to nutrient levels | extracellular matrix; extracellular space; insulin-like growth factor ternary complex | insulin-like growth factor binding | Rattus norvegicus | Cell adhesion Direct protein sequencing Glycoprotein Leucine-rich repeat Reference proteome Repeat Secreted Signal | MALRTGGPAL | MALRTGGPALVVLLAFWVALGPCHLQGTDPGASADAEGPQCPVACTCSHDDYTDELSVFCSSKNLTHLPDDIPVSTRALWLDGNNLSSIPSAAFQNLSSLDFLNLQGSWLRSLEPQALLGLQNLYYLHLERNRLRNLAVGLFTHTPSLASLSLSSNLLGRLEEGLFQGLSHLWDLNLGWNSLVVLPDTVFQGLGNLHELVLAGNKLTYLQPALFCGLGELRELDLSRNALRSVKANVFVHLPRLQKLYLDRNLITAVAPGAFLGMKALRWLDLSHNRVAGLMEDTFPGLLGLHVLRLAHNAIASLRPRTFKDLHFLEELQ... | cell adhesion cellular response to dexamethasone stimulus cellular response to epidermal growth factor stimulus cellular response to growth hormone stimulus cellular response to interleukin-1 response to nutrient levels extracellular matrix; extracellular space; insulin-like growth factor ternary complex insulin-like g... |
apoptotic process blood vessel development cAMP-mediated signaling cell cycle cellular response to 2,3,7,8-tetrachlorodibenzodioxine cellular response to cAMP cellular response to forskolin cellular response to molecule of bacterial origin circadian regulation of gene expression negative regulation of DNA-templated tra... | aryl hydrocarbon receptor complex; chromatin; cytoplasm; cytosol; cytosolic aryl hydrocarbon receptor complex; nuclear aryl hydrocarbon receptor complex; nucleoplasm; nucleus; protein-containing complex; transcription regulator complex | cis-regulatory region sequence-specific DNA binding DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific E-box binding Hsp90 protein binding nuclear receptor activity protein heterodimerization activity protein homodimerization activity RNA polymera... | Homo sapiens | 3D-structure Acetylation Activator ADP-ribosylation Biological rhythms Cell cycle Cytoplasm DNA-binding Nucleus Receptor Reference proteome Repeat Repressor Retinitis pigmentosa Transcription Transcription regulation | MNSSSANITY | MNSSSANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSSPTERNGGQDNCRAANFREGLNLQEGEFLLQALNGFVLVVTTDALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNPSQCTESGQGIEEATGLPQTVVCYNPDQIPPENSPLMERCFICRLRCLLDNSSGFLAMNFQGKLKYLHGQKKKGKDGSILPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPIGCDAKGRIVLGYTEAELCTRGS... | apoptotic process blood vessel development cAMP-mediated signaling cell cycle cellular response to 2,3,7,8-tetrachlorodibenzodioxine cellular response to cAMP cellular response to forskolin cellular response to molecule of bacterial origin circadian regulation of gene expression negative regulation of DNA-templated tra... |
Cajal body organization chromatin organization DNA damage response dorsal/ventral axis specification, ovarian follicular epithelium double-strand break repair heat shock-mediated polytene chromosome puffing innate immune response maintenance of protein location in nucleus nucleolus organization polytene chromosome puff... | Cajal body; chromosome; euchromatin; histone locus body; nucleolus; polytene chromosome; polytene chromosome puff; site of DNA damage | DNA binding histone binding NAD binding NAD+ ADP-ribosyltransferase activity NAD+-protein ADP-ribosyltransferase activity NAD+-protein-serine ADP-ribosyltransferase activity nucleotidyltransferase activity zinc ion binding | Drosophila melanogaster | ADP-ribosylation Alternative splicing Chromatin regulator Chromosome DNA-binding Glycosyltransferase Metal-binding NAD Nucleotidyltransferase Nucleus Reference proteome Repeat Transferase Zinc Zinc-finger | MDIELPYLAE | MDIELPYLAEYARTGRATCKGCKSTISKDTLRIAVMVQSAFHDAKVPNWFHKTCFFKNQRPSSVGDIQNIGNLRFADQKELTDLVENIQEVISAQLGKKRSKAFNLALKDFGIEYAKSSRSTCRGCEQKINKDLVRLRKTVYDTEVGMKYGGQPLWHHLECFAQLRSELGWFASGEDMPGFQSLADDDQAKVKNAIPPIKSEELPDTKRAKMELSDTNEEGEKKQRLKDQNDAYFRFRDDIKNKMKKKDIDILLKFNNQQPVTGDTEKLFDQTADLLTFGAIESCSECNSCQFIVNKSGYICNGNHSEWTKCNKLLKEPT... | Cajal body organization chromatin organization DNA damage response dorsal/ventral axis specification, ovarian follicular epithelium double-strand break repair heat shock-mediated polytene chromosome puffing innate immune response maintenance of protein location in nucleus nucleolus organization polytene chromosome puff... |
apoptotic process cellular response to starvation epithelial cell differentiation intermediate filament organization regulation of protein secretion | cytoplasm; cytoskeleton; cytosol; intermediate filament; intermediate filament cytoskeleton | structural constituent of cytoskeleton | Homo sapiens | Apoptosis Coiled coil Cytoplasm Direct protein sequencing Intermediate filament Keratin Phosphoprotein Reference proteome | MDFSRRSFHR | MDFSRRSFHRSLSSSLQAPVVSTVGMQRLGTTPSVYGGAGGRGIRISNSRHTVNYGSDLTGGGDLFVGNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNAPRAGRDYSAYYRQIEELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTVEADLQGLNKVFDDLTLHKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTELRRTSQSLEIELQSHLSMKESLEHTLEETKAR... | apoptotic process cellular response to starvation epithelial cell differentiation intermediate filament organization regulation of protein secretion cytoplasm; cytoskeleton; cytosol; intermediate filament; intermediate filament cytoskeleton structural constituent of cytoskeleton Homo sapiens Apoptosis Coiled coil Cytop... |
epidermis development intermediate filament organization keratinization keratinocyte activation keratinocyte development keratinocyte migration keratinocyte proliferation peptide cross-linking positive regulation of epidermis development | cornified envelope; cytoplasm; cytosol; extracellular exosome; extracellular space; intermediate filament; keratin filament; membrane; nucleus | cytoskeletal protein binding structural constituent of cytoskeleton structural constituent of skin epidermis | Homo sapiens | Coiled coil Cytoplasm Disease variant Ichthyosis Intermediate filament Keratin Methylation Phosphoprotein Reference proteome | MSCQISCKSR | MSCQISCKSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYLDGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSKVDLLNQEIEFLKVLYDAE... | epidermis development intermediate filament organization keratinization keratinocyte activation keratinocyte development keratinocyte migration keratinocyte proliferation peptide cross-linking positive regulation of epidermis development cornified envelope; cytoplasm; cytosol; extracellular exosome; extracellular space... |
entrainment of circadian clock by photoperiod phototransduction, visible light retina development in camera-type eye retinal cell apoptotic process signal transduction visual perception | photoreceptor disc membrane; photoreceptor outer segment membrane; plasma membrane | 3',5'-cyclic-GMP phosphodiesterase activity 3',5'-cyclic-nucleotide phosphodiesterase activity metal ion binding | Homo sapiens | Acetylation Alternative splicing Cell projection cGMP Congenital stationary night blindness Disease variant Hydrolase Lipoprotein Magnesium Manganese Membrane Metal-binding Prenylation Reference proteome Repeat Retinitis pigmentosa Sensory transduction Vision Zinc | MSLSEEQARS | MSLSEEQARSFLDQNPDFARQYFGKKLSPENVAAACEDGCPPDCDSLRDLCQVEESTALLELVQDMQESINMERVVFKVLRRLCTLLQADRCSLFMYRQRNGVAELATRLFSVQPDSVLEDCLVPPDSEIVFPLDIGVVGHVAQTKKMVNVEDVAECPHFSSFADELTDYKTKNMLATPIMNGKDVVAVIMAVNKLNGPFFTSEDEDVFLKYLNFATLYLKIYHLSYLHNCETRRGQVLLWSANKVFEELTDIERQFHKAFYTVRAYLNCERYSVGLLDMTKEKEFFDVWSVLMGESQPYSGPRTPDGREIVFYKVIDYV... | entrainment of circadian clock by photoperiod phototransduction, visible light retina development in camera-type eye retinal cell apoptotic process signal transduction visual perception photoreceptor disc membrane; photoreceptor outer segment membrane; plasma membrane 3',5'-cyclic-GMP phosphodiesterase activity 3',5'-c... |
ketone body biosynthetic process leucine catabolic process lipid metabolic process mitochondrion organization | cytosol; mitochondrial matrix; mitochondrion; peroxisomal matrix; peroxisome; protein-containing complex | hydroxymethylglutaryl-CoA lyase activity magnesium ion binding manganese ion binding metal ion binding structural molecule activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Disease variant Disulfide bond Lipid metabolism Lyase Metal-binding Mitochondrion Peroxisome Reference proteome Transit peptide | MAAMRKALPR | MAAMRKALPRRLVGLASLRAVSTSSMGTLPKRVKIVEVGPRDGLQNEKNIVSTPVKIKLIDMLSEAGLSVIETTSFVSPKWVPQMGDHTEVLKGIQKFPGINYPVLTPNLKGFEAAVAAGAKEVVIFGAASELFTKKNINCSIEESFQRFDAILKAAQSANISVRGYVSCALGCPYEGKISPAKVAEVTKKFYSMGCYEISLGDTIGVGTPGIMKDMLSAVMQEVPLAALAVHCHDTYGQALANTLMALQMGVSVVDSSVAGLGGCPYAQGASGNLATEDLVYMLEGLGIHTGVNLQKLLEAGNFICQALNRKTSSKVAQ... | ketone body biosynthetic process leucine catabolic process lipid metabolic process mitochondrion organization cytosol; mitochondrial matrix; mitochondrion; peroxisomal matrix; peroxisome; protein-containing complex hydroxymethylglutaryl-CoA lyase activity magnesium ion binding manganese ion binding metal ion binding st... |
protein complex oligomerization suppression by virus of host autophagy virus-mediated pore formation in host cell membrane | host cell plasma membrane; membrane; virion membrane | monoatomic ion channel activity proton transmembrane transporter activity | Influenza A virus | 3D-structure Alternative splicing Disulfide bond Glycoprotein Host cell membrane Host membrane Host-virus interaction Hydrogen ion transport Inhibition of host autophagy by virus Ion channel Ion transport Lipoprotein Membrane Palmitate Phosphoprotein Reference proteome Signal-anchor Transmembrane Transmembrane helix Tr... | MSLLTEVETP | MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGILHLILWILDRLFFKCIYRLFKHGLKRGPSTEGVPESMREEYRKEQQNAVDADDSHFVNIELE | protein complex oligomerization suppression by virus of host autophagy virus-mediated pore formation in host cell membrane host cell plasma membrane; membrane; virion membrane monoatomic ion channel activity proton transmembrane transporter activity Influenza A virus 3D-structure Alternative splicing Disulfide bond Gly... |
cholesterol metabolic process lipid transport | cell surface; clathrin-coated pit; early endosome; Golgi apparatus; late endosome; low-density lipoprotein particle; lysosome | calcium ion binding low-density lipoprotein particle receptor activity | Cricetulus griseus | Cell membrane Cholesterol metabolism Coated pit Disulfide bond EGF-like domain Endocytosis Endosome Glycoprotein Golgi apparatus LDL Lipid metabolism Lipid transport Lysosome Membrane Phosphoprotein Receptor Reference proteome Repeat Signal Steroid metabolism Sterol metabolism Transmembrane Transmembrane helix Transpor... | MSTADLRLRW | MSTADLRLRWAIALLLAAAGAAAEDTCDRNEFRCRDGKCIASKWVCDGSPECPDGSDESSETCMSVTCQSKEFSCGGRVSRCIPNSWRCDGQTDCENGSDEQGCAPKTCSQDEFRCQDGKCISQKFVCDQDQDCVDGSDEAHCQAATCGPAHFRCNSSACIPSLWACDGDDDCEDGSDEWPQNCGGRDTAAAWSSSPCSSLEFHCGSSECIHRSWVCDGSADCKDKSDEEHCVTATCRPDEFQCADGTCIHGSRQCDREYDCKDMSDELGCINVTQCDGPNKFKCHSGECIALDKVCDSMRDCRDWSDEPIKDCRTNECL... | cholesterol metabolic process lipid transport cell surface; clathrin-coated pit; early endosome; Golgi apparatus; late endosome; low-density lipoprotein particle; lysosome calcium ion binding low-density lipoprotein particle receptor activity Cricetulus griseus Cell membrane Cholesterol metabolism Coated pit Disulfide... |
cholesterol metabolic process dendrite morphogenesis glycoprotein transport lipid transport positive regulation of dendrite development receptor-mediated endocytosis ventral spinal cord development very-low-density lipoprotein particle clearance | clathrin-coated pit; receptor complex; very-low-density lipoprotein particle | apolipoprotein binding calcium ion binding calcium-dependent protein binding reelin receptor activity very-low-density lipoprotein particle binding very-low-density lipoprotein particle receptor activity | Oryctolagus cuniculus | Cholesterol metabolism Coated pit Disulfide bond EGF-like domain Endocytosis Glycoprotein Isopeptide bond Lipid metabolism Lipid transport Membrane Receptor Reference proteome Repeat Signal Steroid metabolism Sterol metabolism Transmembrane Transmembrane helix Transport Ubl conjugation VLDL | MGTSARRALW | MGTSARRALWLLLALCWALRESGATATGRKTKCEASQFQCTNGRCITQLWKCDGDEDCVDGSDEKNCVKKTCAESDFVCNNGQCIPNRWQCDGDPDCEDGSDESPEQCHMRTCRINEISCGARSTQCIPVSWRCDGESDCDSGEDEENCGNVTCSSDEFTCSSGRCISRNFVCNGQDDCSDGSDELDCAPPTCGAHEFQCSTSSCIPISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQCGSGECIHKKWRCDGDPDCKDGSDEVNCPSRTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDEVNCKNVNQCLG... | cholesterol metabolic process dendrite morphogenesis glycoprotein transport lipid transport positive regulation of dendrite development receptor-mediated endocytosis ventral spinal cord development very-low-density lipoprotein particle clearance clathrin-coated pit; receptor complex; very-low-density lipoprotein partic... |
suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy | extracellular region; host cell Golgi membrane; host cell plasma membrane; membrane; virion component | GTP binding SH3 domain binding | Human immunodeficiency virus type 1 group M subtype B | AIDS Apoptosis Early protein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host autophagy by virus Inhibition of host MHC class I molecule presentation by virus Inhibition of host MHC class II molecule presentation by viru... | MGGKWSKRSM | MGGKWSKRSMAGWPTVRERMRRAEPAAERMRRAEPAADGVGAVSRDLERHGAITSSNTAATNADCAWLEAQEEEEVGFPVRPQVPLRPMTHKAAMDLSHFLKEKGGLEGLIHSQQRQDILDLWVYHTQGYFPDWQNYTPGGTRWPLTFGWCFKLVPVEPEKIEEANAGENNCLLHPMSQHGMDDPEREGLEWRFDSRLAFHHVARELHPEYYKN | suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy extracellular region; host cell Golgi membrane; host cell plasma membrane; membr... |
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral p... | host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane | structural molecule activity | Human immunodeficiency virus type 1 group M subtype B | 3D-structure AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Li... | MRATEIRKNY | MRATEIRKNYQHLWKGGTLLLGMLMICSAAEQLWVTVYYGVPVWKEATTTLFCASDAKAYDTEVHNVWATHACVPTDPNPQEVKLENVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVTLNCTDLRNATNTTSSSWETMEKGEIKNCSFNITTSIRDKVQKEYALFYNLDVVPIDNASYRLISCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNDKKFNGTGPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEIVIRSENFTNNAKTIIVQLNESVVINCTRPNNNTRKSINIGPGRALYTTGEIIGD... | clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral p... |
viral budding via host ESCRT complex | host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane | RNA binding structural molecule activity zinc ion binding | Human immunodeficiency virus type 1 group M subtype B | 3D-structure AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Methylation Myristate Phosphoprotein Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucleoprote... | MGARASVLSA | MGARASVLSAGELDKWEKIRLRPGGKKQYRLKHIVWASRELERFAVDPGLLETSEGCRQILGQLQPSLQTGSEELRSLYNTVATLYCVHQKIEVKDTKEALEKIEEEQNKSKKKAQQAAADTGNSSQVSQNYPIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTNNPPIPVGEIYKRWIILGLNKIVRMYSPTSILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNWMTET... | viral budding via host ESCRT complex host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane RNA binding structural molecule activity zinc ion binding Human immunodeficiency virus type 1 group M subtype B 3D-structure AIDS Capsid protein Host cell membrane ... |
DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by viru... | extracellular region; host cell cytoplasm; host cell nucleolus | actinin binding cyclin binding metal ion binding protein domain specific binding protein serine/threonine phosphatase inhibitor activity RNA-binding transcription regulator activity trans-activation response element binding | Human immunodeficiency virus type 1 group M subtype B | Acetylation Activator AIDS Alternative splicing Apoptosis Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Isopeptide bond Metal-binding Methylation Modulation of host chromatin by virus Modulation of host PP1 ... | MEPVDPNLEP | MEPVDPNLEPWKHPGSQPRTACNNCYCKKCCFHCQVCFTKKGLGISYGRKKRRQRRRPPQDSQTHQSSLSKQPTSQLRGDPTGPTESKKKVERETETDPVH | DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by viru... |
cell cycle cell division DNA recombination DNA repair DNA replication | virion component | ATP binding DNA ligase (ATP) activity metal ion binding | African swine fever virus | 3D-structure ATP-binding Cell cycle Cell division DNA damage DNA recombination DNA repair DNA replication Ligase Metal-binding Nucleotide-binding Reference proteome Virion | MLNQFPGQYS | MLNQFPGQYSNNIFCFPPIESETKSGKKASWIICVQVVQHNTIIPITDEMFSTDVKDAVAEIFTKFFVEEGAVRISKMTRVTEGKNLGKKNATTVVHQAFKDALSKYNRHARQKRGAHTNRGMIPPMLVKYFNIIPKTFFEEETDPIVQRKRNGVRAVACQQGDGCILLYSRTEKEFLGLDNIKKELKQLYLFIDVRVYLDGELYLHRKPLQWIAGQANAKTDSSELHFYVFDCFWSDQLQMPSNKRQQLLTNIFKQKEDLTFIHQVENFSVKNVDEALRLKAQFIKEGYEGAIVRNANGPYEPGYNNYHSAHLAKLKPL... | cell cycle cell division DNA recombination DNA repair DNA replication virion component ATP binding DNA ligase (ATP) activity metal ion binding African swine fever virus 3D-structure ATP-binding Cell cycle Cell division DNA damage DNA recombination DNA repair DNA replication Ligase Metal-binding Nucleotide-binding Ref... |
cytoplasmic translation translation translation at postsynapse translation at presynapse | cytoplasm; cytosol; cytosolic large ribosomal subunit; cytosolic ribosome; nucleolus; nucleus; postsynapse; postsynaptic density; presynapse; ribosome; synapse | large ribosomal subunit rRNA binding structural constituent of ribosome | Mus musculus | 3D-structure Acetylation Isopeptide bond Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding Ubl conjugation | MPPKFDPNEV | MPPKFDPNEVKVVYLRCTGGEVGATSALAPKIGPLGLSPKKVGDDIAKATGDWKGLRITVKLTIQNRQAQIEVVPSASALIIKALKEPPRDRKKQKNIKHSGNITFDEIVNIARQMRHRSLARELSGTIKEILGTAQSVGCNVDGRHPHDIIDDINSGAVECPAS | cytoplasmic translation translation translation at postsynapse translation at presynapse cytoplasm; cytosol; cytosolic large ribosomal subunit; cytosolic ribosome; nucleolus; nucleus; postsynapse; postsynaptic density; presynapse; ribosome; synapse large ribosomal subunit rRNA binding structural constituent of ribosome... |
cytoplasmic translation | cytoplasm; cytosol; cytosolic large ribosomal subunit; cytosolic ribosome; endoplasmic reticulum; nucleolus; polysomal ribosome; rough endoplasmic reticulum; synapse | RNA binding structural constituent of ribosome | Mus musculus | 3D-structure Cytoplasm Endoplasmic reticulum Isopeptide bond Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation | MGVDIRHNKD | MGVDIRHNKDRKVRRKEPKSQDIYLRLLVKLYRFLARRTNSTFNQVVLKRLFMSRTNRPPLSLSRMIRKMKLPGRENKTAVVVGTVTDDVRILEVPKLKVCALRVSSRARSRILKAGGKILTFDQLALESPKGRGTVLLSGPRKGREVYRHFGKAPGTPHSHTKPYVRSKGRKFERARGRRASRGYKN | cytoplasmic translation cytoplasm; cytosol; cytosolic large ribosomal subunit; cytosolic ribosome; endoplasmic reticulum; nucleolus; polysomal ribosome; rough endoplasmic reticulum; synapse RNA binding structural constituent of ribosome Mus musculus 3D-structure Cytoplasm Endoplasmic reticulum Isopeptide bond Phosphopr... |
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosomal small subunit assembly translation | cytoplasm; cytosol; cytosolic small ribosomal subunit | metal ion binding RNA binding structural constituent of ribosome | Saccharomyces cerevisiae | 3D-structure Cytoplasm Metal-binding Methylation Reference proteome Ribonucleoprotein Ribosomal protein Zinc Zinc-finger | MVLVQDLLHP | MVLVQDLLHPTAASEARKHKLKTLVQGPRSYFLDVKCPGCLNITTVFSHAQTAVTCESCSTILCTPTGGKAKLSEGTSFRRK | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosomal small subunit assembly translation cytoplasm; cytosol; cytosolic small ribosomal subunit metal ion binding RNA binding structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Cytoplasm Metal-binding Meth... |
osteoblast differentiation positive regulation of proteasomal protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process | cytoplasm; cytoplasmic ribonucleoprotein granule; cytosol; extracellular region; ficolin-1-rich granule lumen; membrane; nucleoplasm; nucleus; P-body; proteasome accessory complex; proteasome complex; proteasome regulatory particle, base subcomplex; secretory granule lumen | ATP binding ATP hydrolysis activity proteasome-activating activity | Homo sapiens | 3D-structure Acetylation Alternative splicing ATP-binding Cytoplasm Direct protein sequencing Nucleotide-binding Phosphoprotein Proteasome Reference proteome Ubl conjugation | MPDYLGADQR | MPDYLGADQRKTKEDEKDDKPIRALDEGDIALLKTYGQSTYSRQIKQVEDDIQQLLKKINELTGIKESDTGLAPPALWDLAADKQTLQSEQPLQVARCTKIINADSEDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMA... | osteoblast differentiation positive regulation of proteasomal protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process cytoplasm; cytoplasmic ribonucleoprotein granule; cytosol; extracellular region; ficolin-1-rich granule lumen; membrane;... |
intracellular iron ion homeostasis peptide metabolic process protein processing involved in protein targeting to mitochondrion protein stabilization | mitochondrial matrix; mitochondrion | metal ion binding metalloendopeptidase activity | Saccharomyces cerevisiae | Hydrolase Metal-binding Metalloprotease Mitochondrion Protease Reference proteome Transit peptide Zinc | MLRTIILKAG | MLRTIILKAGSNASIPSPSRQNKLLRFFATAGAVSRTSPGSIKKIFDDNSYWRNINGQDANNSKISQYLFKKNKTGLFKNPYLTSPDGLRKFSQVSLQQAQELLDKMRNDFSESGKLTYIMNLDRLSDTLCRVIDLCEFIRSTHPDDAFVRAAQDCHEQMFEFMNVLNTDVSLCNILKSVLNNPEVSSKLSAEELKVGKILLDDFEKSGIYMNPDVREKFIQLSQEISLVGQEFINHTDYPGSNSVKIPCKDLDNSKVSTFLLKQLNKDVKGQNYKVPTFGYAAYALLKSCENEMVRKKLWTALHSCSDKQVKRLSHLIK... | intracellular iron ion homeostasis peptide metabolic process protein processing involved in protein targeting to mitochondrion protein stabilization mitochondrial matrix; mitochondrion metal ion binding metalloendopeptidase activity Saccharomyces cerevisiae Hydrolase Metal-binding Metalloprotease Mitochondrion Proteas... |
Golgi to vacuole transport intracellular protein transport vesicle targeting, trans-Golgi to endosome vesicle-mediated transport | AP-1 adaptor complex; clathrin-coated pit; cytosol | clathrin binding | Saccharomyces cerevisiae | Cell membrane Coated pit Membrane Protein transport Reference proteome Transport | MPPLDKRIKK | MPPLDKRIKKFLKDSIRIAPKISGKGELSELRTGLVSQYPQTRKDAIKKTIQQMTLGKDVSSLFPDVLKNIATIDVEQKKLVYLYVMNYAETHPELCILAVNTFITDAQDPNPLIRCMAIRTMSMIRVDKILEYIETPLRRTLHDDNAYVRKTAVICVAKLFQLNKDLCVELGVVEDLVNALDDSNPLVIANATAALIEIHNMDMDAVDLSSLIQSHVSQFLLALNECTEWARIIILGTLSEYSAKDSLEAQDIIDRVTAHLQHVNPAVVLATIKVIVRNLPQIEYSSNSLIMKRLSSAFVSLMSTPPEMQYVALKNIRI... | Golgi to vacuole transport intracellular protein transport vesicle targeting, trans-Golgi to endosome vesicle-mediated transport AP-1 adaptor complex; clathrin-coated pit; cytosol clathrin binding Saccharomyces cerevisiae Cell membrane Coated pit Membrane Protein transport Reference proteome Transport MPPLDKRIKK MPPLD... |
intracellular signal transduction protein phosphorylation proteolysis | cytoplasm; nucleus | ATP binding calcium-dependent protein serine/threonine kinase activity calmodulin binding calmodulin-dependent protein kinase activity protein kinase activity protein serine kinase activity | Saccharomyces cerevisiae | ATP-binding Cytoplasm Kinase Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MFTSQRQLRQ | MFTSQRQLRQNGSPMSSSRSSQHSSGTASPISDSPASNRSYGRDLRGLMGIDIPANEPAFNRANSSDTIYFRPKKIYKMEHEHPSRSTLVQLQTRSQPDDVASSQVNPEGGTDDLELGDPCGNQSLYTIGAEYVPDLDFTKLVNEWQKSTEDLYEFRSSATPQVQIKDSGKGNYELWSSPDAILTQNKLRRDSFSQENSDSLSPEDSILSRNLHSKVKPIPLPRNSQQIFTPLSNLEAERRSSYTTSSNNNSITQNNKFSFAKLKYSLPTQSSAVPASFDSNASSLNFLPTTTLSTLSELQISPNDMMDLIQKLPRNFLN... | intracellular signal transduction protein phosphorylation proteolysis cytoplasm; nucleus ATP binding calcium-dependent protein serine/threonine kinase activity calmodulin binding calmodulin-dependent protein kinase activity protein kinase activity protein serine kinase activity Saccharomyces cerevisiae ATP-binding Cyt... |
G1/S transition of mitotic cell cycle phosphorylation regulation of G2/M transition of mitotic cell cycle regulation of gene expression response to organic substance signal transduction | cyclin-dependent protein kinase holoenzyme complex; cytoplasm; nucleus | ATP binding cyclin binding cyclin-dependent protein serine/threonine kinase activity protein serine kinase activity | Saccharomyces cerevisiae | ATP-binding Kinase Nucleotide-binding Reference proteome Serine/threonine-protein kinase Transferase | MATDTERCIF | MATDTERCIFRAFGQDFILNKHFHLTGKIGRGSHSLICSSTYTESNEETHVAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNIVWLFDTDIVFYPNGALNGVYLYEELMECDLSQIIRSEQRLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAELLGRKPMFEGKDYVDHLNHILQILGTPPEETLQEIASQKVYNYIFQFGNIPGRSFESILPGANPEALELLKKMLEFDPKKRITVEDALEHPYLSM... | G1/S transition of mitotic cell cycle phosphorylation regulation of G2/M transition of mitotic cell cycle regulation of gene expression response to organic substance signal transduction cyclin-dependent protein kinase holoenzyme complex; cytoplasm; nucleus ATP binding cyclin binding cyclin-dependent protein serine/thre... |
maturation of SSU-rRNA maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosome biogenesis | nucleolus; nucleoplasm; small-subunit processome | ATP binding ATP hydrolysis activity helicase activity identical protein binding RNA binding RNA helicase activity | Saccharomyces cerevisiae | ATP-binding Helicase Hydrolase Nucleotide-binding Nucleus Reference proteome RNA-binding rRNA processing | MAANSNSRVA | MAANSNSRVASNHTSKKQKVRRNIHPFTNNTRIKRASKIVKFNDSGEGDHVSDQRSNKENVLTYKSLKSRASDLLKMRETLPVYQHKREIMSYIESNPVTVLIGETGSGKSTQIPQFVLEKLYDTKKHGSIAVTQPRRVAAINLATRVAQEHGCKLGEQVGYSVRFDNTTTTRTRLKYLTDGMLLRELMMNSDLREYSVIVIDEAHERTVLTDLILGFLKSLIQGPRPDLRIIVMSATLQAEKFSEFFNNAPILFVEGRKFDVKQYYLKAPTDDIVDAVIRCCIQINQGEELGDILCFLPGQEEIDKAVTIMEKIAKYVS... | maturation of SSU-rRNA maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosome biogenesis nucleolus; nucleoplasm; small-subunit processome ATP binding ATP hydrolysis activity helicase activity identical protein binding RNA binding RNA helicase activity Saccharomyces cerevisiae ... |
CTP biosynthetic process DNA damage response DNA repair GTP biosynthetic process nucleoside triphosphate biosynthetic process phosphorylation UTP biosynthetic process | cytosol; mitochondrial intermembrane space; mitochondrion | ATP binding metal ion binding nucleoside diphosphate kinase activity | Saccharomyces cerevisiae | 3D-structure ATP-binding Cytoplasm DNA damage DNA repair Kinase Magnesium Metal-binding Mitochondrion Nucleotide metabolism Nucleotide-binding Phosphoprotein Reference proteome Transferase | MSSQTERTFI | MSSQTERTFIAVKPDGVQRGLVSQILSRFEKKGYKLVAIKLVKADDKLLEQHYAEHVGKPFFPKMVSFMKSGPILATVWEGKDVVRQGRTILGATNPLGSAPGTIRGDFGIDLGRNVCHGSDSVDSAEREINLWFKKEELVDWESNQAKWIYE | CTP biosynthetic process DNA damage response DNA repair GTP biosynthetic process nucleoside triphosphate biosynthetic process phosphorylation UTP biosynthetic process cytosol; mitochondrial intermembrane space; mitochondrion ATP binding metal ion binding nucleoside diphosphate kinase activity Saccharomyces cerevisiae ... |
conidiophore development conidium formation positive regulation of conidiophore development positive regulation of conidium formation positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II sporocarp development involved in asexual reproduction sporulation resulting in... | nucleus | DNA-binding transcription factor activity sequence-specific DNA binding | Emericella nidulans | Conidiation DNA-binding Nucleus Reference proteome Sporulation Transcription Transcription regulation | MASMNQPQPY | MASMNQPQPYMDVHSHLSSGQTYASHPATAGALTHYQYPQQPPVLQPTSTYGPASSYSQYPYPNSVASSQSVPPPTTSISSQVPAQLLPLPVTNHPVPTHGYGNNSGTPMQGYVYDPTGQMAPPGAKPRVTATLWEDEGSLCYQVEAKGVCVARREDNGMINGTKLLNVAGMTRGRRDGILKSEKVRNVVKIGPMHLKGVWIPFDRALEFANKEKITDLLYPLFVQHISNLLYHPANQNQRNMTVPDSRRLEGPQPVVRTPQAQQPPSLHHHSLQTPVPSHMSQPGGRPSLDRAHTFPTPPASASSLIGITSQNNSYDWN... | conidiophore development conidium formation positive regulation of conidiophore development positive regulation of conidium formation positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II sporocarp development involved in asexual reproduction sporulation resulting in... |
2-micrometer plasmid partitioning kinetochore assembly mitotic sister chromatid segregation protein localization to CENP-A containing chromatin rRNA transcription | 2-micrometer circle DNA; CENP-A containing nucleosome; condensed chromosome, centromeric region; nucleus | centromeric DNA binding protein heterodimerization activity sequence-specific DNA binding structural constituent of chromatin | Saccharomyces cerevisiae | 3D-structure Centromere Chromosome DNA-binding Nucleosome core Nucleus Reference proteome Ubl conjugation | MSSKQQWVSS | MSSKQQWVSSAIQSDSSGRSLSNVNRLAGDQQSINDRALSLLQRTRATKNLFPRREERRRYESSKSDLDIETDYEDQAGNLEIETENEEEAEMETEVPAPVRTHSYALDRYVRQKRREKQRKQSLKRVEKKYTPSELALYEIRKYQRSTDLLISKIPFARLVKEVTDEFTTKDQDLRWQSMAIMALQEASEAYLVGLLEHTNLLALHAKRITIMKKDMQLARRIRGQFI | 2-micrometer plasmid partitioning kinetochore assembly mitotic sister chromatid segregation protein localization to CENP-A containing chromatin rRNA transcription 2-micrometer circle DNA; CENP-A containing nucleosome; condensed chromosome, centromeric region; nucleus centromeric DNA binding protein heterodimerization a... |
amino acid metabolic process malate metabolic process pyruvate metabolic process | mitochondrial matrix; mitochondrion | malate dehydrogenase (decarboxylating) (NAD+) activity malic enzyme activity metal ion binding NAD binding oxaloacetate decarboxylase activity | Saccharomyces cerevisiae | Metal-binding Mitochondrion NAD Oxidoreductase Reference proteome Transit peptide | MLRTRLSVSV | MLRTRLSVSVAARSQLTRSLTASRTAPLRRWPIQQSRLYSSNTRSHKATTTRENTFQKPYSDEEVTKTPVGSRARKIFEAPHPHATRLTVEGAIECPLESFQLLNSPLFNKGSAFTQEEREAFNLEALLPPQVNTLDEQLERSYKQLCYLKTPLAKNDFMTSLRVQNKVLYFALIRRHIKELVPIIYTPTEGDAIAAYSHRFRKPEGVFLDITEPDSIECRLATYGGDKDVDYIVVSDSEGILGIGDQGIGGVRIAISKLALMTLCGGIHPGRVLPVCLDVGTNNKKLARDELYMGNKFSRIRGKQYDDFLEKFIKAVKK... | amino acid metabolic process malate metabolic process pyruvate metabolic process mitochondrial matrix; mitochondrion malate dehydrogenase (decarboxylating) (NAD+) activity malic enzyme activity metal ion binding NAD binding oxaloacetate decarboxylase activity Saccharomyces cerevisiae Metal-binding Mitochondrion NAD Ox... |
cellular response to oxidative stress peroxisome organization | cytosol; mitochondrial outer membrane; peroxisomal matrix | glutathione peroxidase activity phospholipid-hydroperoxide glutathione peroxidase activity thioredoxin-dependent peroxiredoxin activity | Saccharomyces cerevisiae | Antioxidant Disulfide bond Membrane Mitochondrion Mitochondrion outer membrane Oxidoreductase Peroxidase Peroxisome Redox-active center Reference proteome | MQEFYSFSPI | MQEFYSFSPIDENGNPFPFNSLRNKVVLIVNVASHCAFTPQYKELEYLYEKYKSHGLVIVAFPCGQFGNQEFEKDKEINKFCQDKYGVTFPILHKIRCNGQKQDPVYKFLKNSVSGKSGIKMIKWNFEKFVVDRNGKVVKRFSCMTRPLELCPIIEELLNQPPEEQI | cellular response to oxidative stress peroxisome organization cytosol; mitochondrial outer membrane; peroxisomal matrix glutathione peroxidase activity phospholipid-hydroperoxide glutathione peroxidase activity thioredoxin-dependent peroxiredoxin activity Saccharomyces cerevisiae Antioxidant Disulfide bond Membrane Mi... |
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