Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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amphisome-lysosome fusion endoplasmic reticulum to Golgi vesicle-mediated transport Golgi to endosome transport Golgi vesicle fusion to target membrane intra-Golgi vesicle-mediated transport intracellular protein transport vacuole fusion, non-autophagic vesicle fusion vesicle fusion with Golgi apparatus | autophagosome membrane; cytosol; endoplasmic reticulum membrane; endosome; endosome membrane; fungal-type vacuole; Golgi apparatus; Golgi cis cisterna membrane; Golgi membrane; membrane; mitochondrion; plasma membrane; SNARE complex; vacuolar membrane | palmitoyltransferase activity SNAP receptor activity | Saccharomyces cerevisiae | 3D-structure Cell membrane Coiled coil Lipoprotein Membrane Methylation Palmitate Phosphoprotein Prenylation Reference proteome Transferase | MRIYYIGVFR | MRIYYIGVFRSGGEKALELSEVKDLSQFGFFERSSVGQFMTFFAETVASRTGAGQRQSIEEGNYIGHVYARSEGICGVLITDKEYPVRPAYTLLNKILDEYLVAHPKEEWADVTETNDALKMKQLDTYISKYQDPSQADAIMKVQQELDETKIVLHKTIENVLQRGEKLDNLVDKSESLTASSKMFYKQAKKSNSCCIIM | amphisome-lysosome fusion endoplasmic reticulum to Golgi vesicle-mediated transport Golgi to endosome transport Golgi vesicle fusion to target membrane intra-Golgi vesicle-mediated transport intracellular protein transport vacuole fusion, non-autophagic vesicle fusion vesicle fusion with Golgi apparatus autophagosome m... |
post-translational protein targeting to membrane, translocation response to unfolded protein | endoplasmic reticulum; endoplasmic reticulum chaperone complex; endoplasmic reticulum lumen | adenyl-nucleotide exchange factor activity ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone unfolded protein binding | Saccharomyces cerevisiae | ATP-binding Chaperone Endoplasmic reticulum Glycoprotein Hydrolase Nucleotide-binding Reference proteome Signal | MRNVLRLLFL | MRNVLRLLFLTAFVAIGSLAAVLGVDYGQQNIKAIVVSPQAPLELVLTPEAKRKEISGLSIKRLPGYGKDDPNGIERIYGSAVGSLATRFPQNTLLHLKPLLGKSLEDETTVTLYSKQHPGLEMVSTNRSTIAFLVDNVEYPLEELVAMNVQEIANRANSLLKDRDARTEDFVNKMSFTIPDFFDQHQRKALLDASSITTGIEETYLVSEGMSVAVNFVLKQRQFPPGEQQHYIVYDMGSGSIKASMFSILQPEDTTQPVTIEFEGYGYNPHLGGAKFTMDIGSLIENKFLETHPAIRTDELHANPKALAKINQAAEKAK... | post-translational protein targeting to membrane, translocation response to unfolded protein endoplasmic reticulum; endoplasmic reticulum chaperone complex; endoplasmic reticulum lumen adenyl-nucleotide exchange factor activity ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone unfolded protein... |
endocytosis Golgi to endosome transport late endosome to vacuole transport via multivesicular body sorting pathway multivesicular body assembly protein localization to endosome protein targeting to vacuole protein transport reticulophagy vacuole inheritance | cytosol; early endosome; endocytic vesicle; endomembrane system; endosome membrane; late endosome; mitochondrial outer membrane; mitochondrion; plasma membrane | GTP binding GTPase activity | Saccharomyces cerevisiae | 3D-structure Direct protein sequencing Endosome GTP-binding Lipoprotein Membrane Methylation Mitochondrion Nucleotide-binding Phosphoprotein Prenylation Protein transport Reference proteome Transport | MNTSVTSIKL | MNTSVTSIKLVLLGEAAVGKSSIVLRFVSNDFAENKEPTIGAAFLTQRVTINEHTVKFEIWDTAGQERFASLAPMYYRNAQAALVVYDVTKPQSFIKARHWVKELHEQASKDIIIALVGNKIDMLQEGGERKVAREEGEKLAEEKGLLFFETSAKTGENVNDVFLGIGEKIPLKTAEEQNSASNERESNNQRVDLNAANDGTSANSACSC | endocytosis Golgi to endosome transport late endosome to vacuole transport via multivesicular body sorting pathway multivesicular body assembly protein localization to endosome protein targeting to vacuole protein transport reticulophagy vacuole inheritance cytosol; early endosome; endocytic vesicle; endomembrane syste... |
endocytosis Golgi to endosome transport intracellular protein transport late endosome to vacuole transport via multivesicular body sorting pathway multivesicular body assembly protein localization to endosome protein targeting to vacuole | cytosol; endomembrane system; endoplasmic reticulum; fungal-type vacuole membrane; late endosome; plasma membrane | GTP binding GTPase activity | Saccharomyces cerevisiae | Cell membrane Direct protein sequencing Endoplasmic reticulum GTP-binding Isopeptide bond Lipoprotein Membrane Nucleotide-binding Phosphoprotein Prenylation Protein transport Reference proteome Transport Ubl conjugation | MLQFKLVLLG | MLQFKLVLLGDSSVGKSSIVHRFVKDTFDELRESTIGAAFLSQSITIHPNDGNETKDVVIKFEIWDTAGQERYKSLAPMYYRNANAALVVYDITQEDSLQKARNWVDELKNKVGDDDLVIYLLGNKVDLCQETPSTETSPDSNEGGDEEQKVRAISTEEAKQYAQEQGLLFREVSAKTGEGVKEIFQDIGEKLYDLKKDEILSKQNRQIGGGNNGQVDINLQRPSTNDPTSCCS | endocytosis Golgi to endosome transport intracellular protein transport late endosome to vacuole transport via multivesicular body sorting pathway multivesicular body assembly protein localization to endosome protein targeting to vacuole cytosol; endomembrane system; endoplasmic reticulum; fungal-type vacuole membrane;... |
amino acid import across plasma membrane amino acid metabolic process monocarboxylic acid transport negative regulation of neural precursor cell proliferation thyroid hormone generation thyroid hormone metabolic process thyroid hormone transport thyroid-stimulating hormone secretion transport across blood-brain barrier... | apical plasma membrane; plasma membrane | amino acid transmembrane transporter activity identical protein binding monocarboxylic acid transmembrane transporter activity thyroid hormone transmembrane transporter activity | Homo sapiens | Acetylation Cell membrane Disease variant Membrane Reference proteome Transmembrane Transmembrane helix Transport | MALQSQASEE | MALQSQASEEAKGPWQEADQEQQEPVGSPEPESEPEPEPEPEPVPVPPPEPQPEPQPLPDPAPLPELEFESERVHEPEPTPTVETRGTARGFQPPEGGFGWVVVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNRQVEFQAAWVGALAMGMIFFCSPIVSIFTDRLGCRITATAGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFAFQPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIRMLGDKIKLAQTFQVLSTFMFVLMLLSLTYRPLLPSSQDTPSKRGVRTLHQRFLAQLRKYFNMRVFRQRT... | amino acid import across plasma membrane amino acid metabolic process monocarboxylic acid transport negative regulation of neural precursor cell proliferation thyroid hormone generation thyroid hormone metabolic process thyroid hormone transport thyroid-stimulating hormone secretion transport across blood-brain barrier... |
coenzyme A biosynthetic process regulation of mitotic cell cycle response to salt stress | chromatin; CoA-synthesizing protein complex; nucleus; phosphopantothenoylcysteine decarboxylase complex | catalytic activity FMN binding identical protein binding protein serine/threonine phosphatase inhibitor activity | Saccharomyces cerevisiae | Coenzyme A biosynthesis Cytoplasm Nucleus Phosphoprotein Protein phosphatase inhibitor Reference proteome | MTAVASTSGK | MTAVASTSGKQDADHNQSIECPRFSRGQKEILLDHEDAKGKDSIINSPVSGRQSISPTLSNATTTTTKSIMNATGTSGAVVSNTPEPGLKRVPAVTFSDLKQQQKQDSLTQLKNDSERTKSPNSNPAPVSNSIPGNHAVIPNHTNTSRTTQLSGSPLVNEMKDYDPKKKDSALKIVDTMKPDKIMATSTPISRENNKVTAKAPTSITLRKEDAQDQANNVSGQINVRSTPEETPVKQSVIPSIIPKRENSKNLDPRLPQDDGKLHVLFGATGSLSVFKIKPMIKKLEEIYGRDRISIQVILTQSATQFFEQRYTKKIIKS... | coenzyme A biosynthetic process regulation of mitotic cell cycle response to salt stress chromatin; CoA-synthesizing protein complex; nucleus; phosphopantothenoylcysteine decarboxylase complex catalytic activity FMN binding identical protein binding protein serine/threonine phosphatase inhibitor activity Saccharomyces ... |
fungal-type cell wall organization IRE1-mediated unfolded protein response pexophagy response to acidic pH response to osmotic stress | fungal-type vacuole; mating projection tip; plasma membrane | transmembrane signaling receptor activity | Saccharomyces cerevisiae | Cell membrane Glycoprotein Membrane Phosphoprotein Reference proteome Signal Stress response Transmembrane Transmembrane helix | MLSFTTKNSF | MLSFTTKNSFRLLLLILSCISTIRAQFFVQSSSSNSSAVSTARSSVSRVSSSSSILSSSMVSSSSADSSSLTSSTSSRSLVSHTSSSTSIASISFTSFSFSSDSSTSSSSSASSDSSSSSSFSISSTSATSESSTSSTQTSTSSSSSLSSTPSSSSSPSTITSAPSTSSTPSTTAYNQGSTITSIINGKTILSNHYTTVTYTPSATADSSNKSKSSGLSKKNRNIVIGCVVGIGVPLILVILALIYMFCIQSSRTDFIDSDGKVVTAYRANKFTKWWYMLLGKKVSDEYHSDSPLGGSASSAGGLDLDEADDVMEQSSLF... | fungal-type cell wall organization IRE1-mediated unfolded protein response pexophagy response to acidic pH response to osmotic stress fungal-type vacuole; mating projection tip; plasma membrane transmembrane signaling receptor activity Saccharomyces cerevisiae Cell membrane Glycoprotein Membrane Phosphoprotein Referen... |
copper ion import intracellular iron ion homeostasis iron ion transport nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | fungal-type vacuole; plasma membrane | ferric-chelate reductase (NADPH) activity ferric-chelate reductase activity metal ion binding | Saccharomyces cerevisiae | Cell membrane Copper Copper transport Electron transport FAD Flavoprotein Glycoprotein Heme Ion transport Iron Iron transport Membrane Metal-binding NADP Oxidoreductase Reference proteome Signal Transmembrane Transmembrane helix Transport | MHWTSILSAI | MHWTSILSAILLFCLSGARASPAKTVIRNKVPLLVTNACTRIFQKVTWEYTSKSKRSSPVCSYEPAFQSMLYCIYETLDEKGYSNKTLEKTFSTIKKNCASYSDALQNMTNSEFYDVLNNGTRHMTPYVKGSANLTYPVEMDTQLRKAYYHALHGFYANLDVGNIYGGIICAYFVAIMAFAGVLHCMNYTPFKTVLLKQKLVGYVRGYLTLPTIGSKHASDFSYFRIFTGYLPTRLEGIIILGYLVLHTVFLAYGYEYDPENIIFKSRRVQVARYVADRSGVLAFAHFPLIVLFAGRNNFLEYISGVKYTSFIMFHKWLG... | copper ion import intracellular iron ion homeostasis iron ion transport nuclear-transcribed mRNA catabolic process, nonsense-mediated decay fungal-type vacuole; plasma membrane ferric-chelate reductase (NADPH) activity ferric-chelate reductase activity metal ion binding Saccharomyces cerevisiae Cell membrane Copper Co... |
plasma membrane lactate transport plasma membrane pyruvate transport plasma membrane selenite transport | cell periphery; fungal-type vacuole; mitochondrion; plasma membrane | secondary active monocarboxylate transmembrane transporter activity selenite:proton symporter activity sialic acid transmembrane transporter activity | Saccharomyces cerevisiae | Acetylation Isopeptide bond Membrane Phosphoprotein Reference proteome Repeat Transmembrane Transmembrane helix Transport Ubl conjugation | MSSSITDEKI | MSSSITDEKISGEQQQPAGRKLYYNTSTFAEPPLVDGEGNPINYEPEVYNPDHEKLYHNPSLPAQSIQDTRDDELLERVYSQDQGVEYEEDEEDKPNLSAASIKSYALTRFTSLLHIHEFSWENVNPIPELRKMTWQNWNYFFMGYFAWLSAAWAFFCVSVSVAPLAELYDRPTKDITWGLGLVLFVRSAGAVIFGLWTDKSSRKWPYITCLFLFVIAQLCTPWCDTYEKFLGVRWITGIAMGGIYGCASATAIEDAPVKARSFLSGLFFSAYAMGFIFAIIFYRAFGYFRDDGWKILFWFSIFLPILLIFWRLLWPETK... | plasma membrane lactate transport plasma membrane pyruvate transport plasma membrane selenite transport cell periphery; fungal-type vacuole; mitochondrion; plasma membrane secondary active monocarboxylate transmembrane transporter activity selenite:proton symporter activity sialic acid transmembrane transporter activit... |
double-strand break repair via nonhomologous end joining mitochondria-associated ubiquitin-dependent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process ribophagy ubiquitin recycling | cytoplasm; cytoplasmic side of mitochondrial outer membrane; endosome membrane; nucleus | protein-containing complex binding ubiquitin binding ubiquitin-dependent protein binding | Saccharomyces cerevisiae | 3D-structure Cytoplasm Direct protein sequencing Endosome Membrane Mitochondrion Mitochondrion outer membrane Nucleus Phosphoprotein Reference proteome Repeat Ubl conjugation pathway WD repeat | MGYQLSATLK | MGYQLSATLKGHDQDVRDVVAVDDSKVASVSRDGTVRLWSKDDQWLGTVVYTGQGFLNSVCYDSEKELLLFGGKDTMINGVPLFATSGEDPLYTLIGHQGNVCSLSFQDGVVISGSWDKTAKVWKEGSLVYNLQAHNASVWDAKVVSFSENKFLTASADKTIKLWQNDKVIKTFSGIHNDVVRHLAVVDDGHFISCSNDGLIKLVDMHTGDVLRTYEGHESFVYCIKLLPNGDIVSCGEDRTVRIWSKENGSLKQVITLPAISIWSVDCMSNGDIIVGSSDNLVRIFSQEKSRWASEDEINELSTQVEKSTISSKTIEFD... | double-strand break repair via nonhomologous end joining mitochondria-associated ubiquitin-dependent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process ribophagy ubiquitin recycling cytoplasm; cytoplasmic side of mitochondrial outer membrane; endosome membrane; nucleus protein-c... |
deadenylation-dependent decapping of nuclear-transcribed mRNA mRNA catabolic process negative regulation of translation | cytoplasmic stress granule | ATP binding eukaryotic initiation factor 4E binding mRNA binding | Saccharomyces cerevisiae | 3D-structure ATP-binding Cytoplasm Growth regulation Nucleotide-binding Phosphoprotein Reference proteome Translation regulation | MELNDPSIIS | MELNDPSIISSSQFSGELSDSDTAAATHKSQQAISNLFQKLAKKGREEKPIGSVESSTDSSNISVATSGNNKESNKKKNKKTAMLNFSSLTDPITNYKPMDLQYKTYAYSMNELYHLKPSLASASYEEDPLISELVRSLPKRKFWRLRMGPPDQKHANNHHFNGNNGGGSWKAGYKNGKNDERRMSRTKNMQGGKRRSQQDDEEKKIDQEMLEMDKNLQLGGDVGHSIADFEDWKAKMKELELKKLSKSKGISNSTAIAPRESASHETPTDLRPVIPRGPSSITDFLNLKRQDKKEESSQQTPGIPVGQPSLSKTSIEQV... | deadenylation-dependent decapping of nuclear-transcribed mRNA mRNA catabolic process negative regulation of translation cytoplasmic stress granule ATP binding eukaryotic initiation factor 4E binding mRNA binding Saccharomyces cerevisiae 3D-structure ATP-binding Cytoplasm Growth regulation Nucleotide-binding Phosphopro... |
protein folding protein import into mitochondrial intermembrane space protein maturation by protein folding | mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrion | 2 iron, 2 sulfur cluster binding oxidoreductase activity protein disulfide isomerase activity protein-disulfide reductase activity thiol oxidase activity | Saccharomyces cerevisiae | 3D-structure Direct protein sequencing Disulfide bond Membrane Mitochondrion Mitochondrion inner membrane Oxidoreductase Protein transport Redox-active center Reference proteome Signal-anchor Transit peptide Translocation Transmembrane Transmembrane helix Transport | MLRNLVVRNA | MLRNLVVRNACRNRPSIQVARGLCRHQTRRLMASSPQFGRNSNQEKTAGFIMGILSMAGALYFIAPNRKPLFASRKVESDKTAEEELSSGGEQSPENEDDNNSKSDENGDDNDSKNDETEAGPQLGGDKIGASKVAEDGELVVLAEEDNKSSEDKDTDESKVSTKDDEQSNEDNATANNQKDENISSENSEENTSDKTLDNNAGSSEKKDPEHSDDEKSQQGQSDDKTTTEDNNGEEESSKKTVSDSENSAKQSESSDEEKEELRKQEEKQMGPTEEEVQHEGAYNPDTGEINWDCPCLGGMAHGPCGEEFKSAFSCFVY... | protein folding protein import into mitochondrial intermembrane space protein maturation by protein folding mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrion 2 iron, 2 sulfur cluster binding oxidoreductase activity protein disulfide isomerase activity protein-disulfide reductase activity th... |
cell division chromosome organization chromosome segregation maintenance of protein location in nucleus | cytoplasm; nucleus; protein phosphatase type 1 complex | protein phosphatase activator activity protein serine/threonine phosphatase inhibitor activity | Saccharomyces cerevisiae | Cell cycle Cell division Leucine-rich repeat Mitosis Nucleus Phosphoprotein Reference proteome Repeat | MDKNSVNKDS | MDKNSVNKDSEEKDERHKIEVVDDTNPDFITADSELTQDLPDDVEVIDLVHLKIKSLEDLNLYRFKNLKQLCLRQNLIESISEVEVLPHDKIVDLDFYDNKIKHISSNVNKLTKLTSLDLSFNKIKHIKNLENLTDLENLYFVQNSISKIENLSTLKSLKNLELGGNKVHSIEPDSFEGLSNLEEIWLGKNSIPRLINLHPLKNLKILSIQSNKLKKIENLEELTNLEELYLSHNFITKIEGLEKNLKLTTLDVTSNKITSLENLNHLSNLTDIWASFNKIDQSFESLGENLSALSRLETIYLEGNPIQLENKTSYRRKL... | cell division chromosome organization chromosome segregation maintenance of protein location in nucleus cytoplasm; nucleus; protein phosphatase type 1 complex protein phosphatase activator activity protein serine/threonine phosphatase inhibitor activity Saccharomyces cerevisiae Cell cycle Cell division Leucine-rich re... |
generation of catalytic spliceosome for first transesterification step mRNA splicing, via spliceosome spliceosomal snRNP assembly spliceosomal tri-snRNP complex assembly spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) | cytoplasm; cytosol; nucleus; spliceosomal complex; U2-type catalytic step 2 spliceosome; U4/U6 x U5 tri-snRNP complex; U5 snRNP | GTP binding GTPase activity U5 snRNA binding | Saccharomyces cerevisiae | 3D-structure GTP-binding mRNA processing mRNA splicing Nucleotide-binding Nucleus Phosphoprotein Reference proteome | MEGDDLFDEF | MEGDDLFDEFGNLIGVDPFDSDEEESVLDEQEQYQTNTFEGSGNNNEIESRQLTSLGSKKELGISLEHPYGKEVEVLMETKNTQSPQTPLVEPVTERTKLQEHTIFTQLKKNIPKTRYNRDYMLSMANIPERIINVGVIGPLHSGKTSLMDLLVIDSHKRIPDMSKNVELGWKPLRYLDNLKQEIDRGLSIKLNGSTLLCTDLESKSRMINFLDAPGHVNFMDETAVALAASDLVLIVIDVVEGVTFVVEQLIKQSIKNNVAMCFVINKLDRLILDLKLPPMDAYLKLNHIIANINSFTKGNVFSPIDNNIIFASTKLGF... | generation of catalytic spliceosome for first transesterification step mRNA splicing, via spliceosome spliceosomal snRNP assembly spliceosomal tri-snRNP complex assembly spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) cytoplasm; cytosol; nucleus; spliceosomal complex; U2-type catalytic step ... |
nuclear division ribosomal large subunit biogenesis rRNA processing | nuclear periphery; nucleolus; preribosome, large subunit precursor | identical protein binding mRNA binding | Saccharomyces cerevisiae | 3D-structure Coiled coil Nucleus Phosphoprotein Reference proteome Ribosome biogenesis Ubl conjugation | MAKGFKLKEL | MAKGFKLKELLSHQKEIEKAEKLENDLKKKKSQELKKEEPTIVTASNLKKLEKKEKKADVKKEVAADTEEYQSQALSKKEKRKLKKELKKMQEQDATEAQKHMSGDEDESGDDREEEEEEEEEEEGRLDLEKLAKSDSESEDDSESENDSEEDEDVVAKEESEEKEEQEEEQDVPLSDVEFDSDADVVPHHKLTVNNTKAMKHALERVQLPWKKHSFQEHQSVTSETNTDEHIKDIYDDTERELAFYKQSLDAVLVARDELKRLKVPFKRPLDYFAEMVKSDEHMDKIKGKLIEEASDKKAREEARRQRQLKKFGKQVQN... | nuclear division ribosomal large subunit biogenesis rRNA processing nuclear periphery; nucleolus; preribosome, large subunit precursor identical protein binding mRNA binding Saccharomyces cerevisiae 3D-structure Coiled coil Nucleus Phosphoprotein Reference proteome Ribosome biogenesis Ubl conjugation MAKGFKLKEL MAKGFK... |
ATP transport cell wall organization GPI anchor biosynthetic process | endoplasmic reticulum; endoplasmic reticulum membrane; fungal-type cell wall; fungal-type vacuole; Golgi membrane; vacuolar membrane | mannose-ethanolamine phosphotransferase activity | Saccharomyces cerevisiae | Cell wall biogenesis/degradation Endoplasmic reticulum Glycoprotein Golgi apparatus GPI-anchor biosynthesis Membrane Reference proteome Transferase Transmembrane Transmembrane helix Vacuole | MWNKTRTTLL | MWNKTRTTLLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQSTPTPPAKRLFLIVGDGLRADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPTESRPGHVAMIAGFYEDVSAVTKGWKSNPVNFDSFFNQSTHTYSFGSPDILPMFKDGASDPNKVDTWMYDHTFEDFTQSSIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGLNKPVHNPFPVSDNYTENWELS... | ATP transport cell wall organization GPI anchor biosynthetic process endoplasmic reticulum; endoplasmic reticulum membrane; fungal-type cell wall; fungal-type vacuole; Golgi membrane; vacuolar membrane mannose-ethanolamine phosphotransferase activity Saccharomyces cerevisiae Cell wall biogenesis/degradation Endoplasmi... |
protein targeting to ER SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition | endoplasmic reticulum membrane; membrane; signal recognition particle receptor complex | GTP binding identical protein binding signal recognition particle binding | Saccharomyces cerevisiae | 3D-structure Endoplasmic reticulum GTP-binding Membrane Nucleotide-binding Receptor Reference proteome Transmembrane Transmembrane helix | MLSNTLIIAC | MLSNTLIIACLLVIGTTIALIAVQKASSKTGIKQKSYQPSIIIAGPQNSGKTSLLTLLTTDSVRPTVVSQEPLSAADYDGSGVTLVDFPGHVKLRYKLSDYLKTRAKFVKGLIFMVDSTVDPKKLTTTAEFLVDILSITESSCENGIDILIACNKSELFTARPPSKIKDALESEIQKVIERRKKSLNEVERKINEEDYAENTLDVLQSTDGFKFANLEASVVAFEGSINKRKISQWREWIDEKL | protein targeting to ER SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition endoplasmic reticulum membrane; membrane; signal recognition particle receptor complex GTP binding identical protein binding signal recognition particle binding Saccharomyces cerevisiae 3D-structure Endopla... |
cellular response to oxidative stress ergosterol biosynthetic process | mitochondrial intermembrane space; mitochondrial outer membrane; mitochondrion | cytochrome-b5 reductase activity, acting on NAD(P)H NADH dehydrogenase activity | Saccharomyces cerevisiae | Direct protein sequencing FAD Flavoprotein Membrane Mitochondrion Mitochondrion outer membrane NAD Oxidoreductase Phosphoprotein Reference proteome Transmembrane Transmembrane helix | MFSRLSRSHS | MFSRLSRSHSKALPIALGTVAIAAATAFYFANRNQHSFVFNESNKVFKGDDKWIDLPISKIEEESHDTRRFTFKLPTEDSEMGLVLASALFAKFVTPKGSNVVRPYTPVSDLSQKGHFQLVVKHYEGGKMTSHLFGLKPNDTVSFKGPIMKWKWQPNQFKSITLLGAGTGINPLYQLAHHIVENPNDKTKVNLLYGNKTPQDILLRKELDALKEKYPDKFNVTYFVDDKQDDQDFDGEISFISKDFIQEHVPGPKESTHLFVCGPPPFMNAYSGEKKSPKDQGELIGILNNLGYSKDQVFKF | cellular response to oxidative stress ergosterol biosynthetic process mitochondrial intermembrane space; mitochondrial outer membrane; mitochondrion cytochrome-b5 reductase activity, acting on NAD(P)H NADH dehydrogenase activity Saccharomyces cerevisiae Direct protein sequencing FAD Flavoprotein Membrane Mitochondrion... |
intracellular mRNA localization mating type switching mRNA transport | cellular bud tip; cytoplasm; cytosol; nucleus | lipid binding mRNA binding sequence-specific mRNA binding | Saccharomyces cerevisiae | 3D-structure Cytoplasm mRNA transport Nucleus Reference proteome RNA-binding Transport | MSKDKDIKVT | MSKDKDIKVTPGTCELVEQILALLSRYLSSYIHVLNKFISHLRRVATLRFERTTLIKFVKKLRFYNDCVLSYNASEFINEGKNELDPEADSFDKVILPIASMFVKCVETFDLLNYYLTQSLQKEILSKTLNEDLTLTAESILAIDDTYNHFVKFSQWMIESLRIGSNLLDLEVVQFAIKCADEDGTNIGETDNIFLQEILPVNSEEEFQTLSAAWHSILDGKLSALDEEFDVVATKWHDKFGKLKN | intracellular mRNA localization mating type switching mRNA transport cellular bud tip; cytoplasm; cytosol; nucleus lipid binding mRNA binding sequence-specific mRNA binding Saccharomyces cerevisiae 3D-structure Cytoplasm mRNA transport Nucleus Reference proteome RNA-binding Transport MSKDKDIKVT MSKDKDIKVTPGTCELVEQILAL... |
nuclear-transcribed mRNA catabolic process, no-go decay rescue of stalled ribosome | cytosolic ribosome | endonuclease activity K63-linked polyubiquitin modification-dependent protein binding polyubiquitin modification-dependent protein binding RNA endonuclease activity ubiquitin binding | Saccharomyces cerevisiae | 3D-structure Reference proteome Repeat Ubl conjugation pathway | MSMDNNDDHE | MSMDNNDDHESKLSILMDMFPAISKSKLQVHLLENNNDLDLTIGLLLKENDDKSTVDNELHQLYDMFPQLDCSVIKDQFVINEKSVESTISDLLNYETLQKLKDNQANSPDSVKRNEKKNNWESTNDHIESIIKFTDAPKNIAQEYLAENGFDTVKAIIKIILDYYDKRDFKKDVDTFKVKRSPNTTVRGGRVQSSTGLAHVLKKGKESANVAQESLKRPRSYKHSLDSPQMVELNELVADNRDLKAINHEFLQKCLQFYDGDVVKVLNISSLLIEDDKNITKTWNFDEGFTLTSRDNCKQHLPKFSTPQISRRNEVGNT... | nuclear-transcribed mRNA catabolic process, no-go decay rescue of stalled ribosome cytosolic ribosome endonuclease activity K63-linked polyubiquitin modification-dependent protein binding polyubiquitin modification-dependent protein binding RNA endonuclease activity ubiquitin binding Saccharomyces cerevisiae 3D-struct... |
coenzyme A biosynthetic process | CoA-synthesizing protein complex; cytoplasm; phosphopantothenoylcysteine decarboxylase complex | catalytic activity FMN binding identical protein binding | Saccharomyces cerevisiae | Coenzyme A biosynthesis Cytoplasm Phosphoprotein Reference proteome | MTDEKVNSDQ | MTDEKVNSDQNMNGKQGVNLISSLPTTQVPVSILTNKERRKSIHDESNFERSDSHEDQSKSNSNRRNIYKNDYSTNLRDFSFANLKQNSERNKDGHEIQINTSMPANTNGQQKRFSPSLPSAVSFTVPEVERLPYHRYSISNKPGKQQQQQEQLQQNQQQEEQQKAQLQEQNQRAKQQEEVKQIQEQVQKKQTERQQLIDEKERIANAIFKENTTNDGTDIRKHSVSSGTSNSEDEVDSPSMEKNSIVHMPGDFIYFNPKSNASKPITAKAAPLSANNSTHKNKEVITAPTGPRVPFTEFFQKEDDKKFHILIGATGSVA... | coenzyme A biosynthetic process CoA-synthesizing protein complex; cytoplasm; phosphopantothenoylcysteine decarboxylase complex catalytic activity FMN binding identical protein binding Saccharomyces cerevisiae Coenzyme A biosynthesis Cytoplasm Phosphoprotein Reference proteome MTDEKVNSDQ MTDEKVNSDQNMNGKQGVNLISSLPTTQVPV... |
cellular response to oxidative stress negative regulation of protein polymerization | cytoplasm; nucleus | ATP binding sulfiredoxin activity | Saccharomyces cerevisiae | Antioxidant ATP-binding Cytoplasm Disulfide bond Magnesium Nucleotide-binding Nucleus Oxidoreductase Reference proteome | MSLQSNSVKP | MSLQSNSVKPTEIPLSEIRRPLAPVLDPQKIDAMVATMKGIPTASKTCSLEQAEAAASAGELPPVDVLGVRVKGQTLYYAFGGCHRLQAYDRRARETQNAAFPVRCRVLPATPRQIRMYLGSSLDIE | cellular response to oxidative stress negative regulation of protein polymerization cytoplasm; nucleus ATP binding sulfiredoxin activity Saccharomyces cerevisiae Antioxidant ATP-binding Cytoplasm Disulfide bond Magnesium Nucleotide-binding Nucleus Oxidoreductase Reference proteome MSLQSNSVKP MSLQSNSVKPTEIPLSEIRRPLAPVL... |
mRNA branch site recognition mRNA splicing, via spliceosome spliceosomal complex assembly | commitment complex; nuclear speck; nucleus; U2-type prespliceosome; U2AF complex | mRNA binding poly-pyrimidine tract binding pre-mRNA 3'-splice site binding pre-mRNA branch point binding | Saccharomyces cerevisiae | mRNA processing mRNA splicing Phosphoprotein Reference proteome RNA-binding | MADEKRLEDL | MADEKRLEDLRSKIMESIGKSEKDVVPIENKRFNTDNAVIDTHFKRQKSDGELPKAPKSRNVSHSNNRGPSSIITMSTNRTTYEQTRAGPHRQSYRDASGRSYNRENRYSSHNTGPQWNNNPYNRQRDERRGRNERFDRRGRNGNGNYDRFNYQRKNEGSKFNGDRDKRQLQTNKYDMNYNSQNVMYPGSSFDSPAYYNMASSKANSRLVISGLSQSSDPSIVARLKDLLENFISGLQKTESNAEDFKISNFYIGEGRPDHIIVEFSSQICSTMVLACRSFFNAKLGTFDLKWRRPNDYVQQLDHLVDFCRGTVIALENL... | mRNA branch site recognition mRNA splicing, via spliceosome spliceosomal complex assembly commitment complex; nuclear speck; nucleus; U2-type prespliceosome; U2AF complex mRNA binding poly-pyrimidine tract binding pre-mRNA 3'-splice site binding pre-mRNA branch point binding Saccharomyces cerevisiae mRNA processing mR... |
cellular response to oxidative stress | cytoplasm; cytosol; nucleus | L-methionine-(R)-S-oxide reductase activity | Saccharomyces cerevisiae | 3D-structure Cytoplasm Nucleus Oxidoreductase Reference proteome Stress response | MGSSTGFHHA | MGSSTGFHHADHVNYSSNLNKEEILEQLLLSYEGLSDGQVNWVCNLSNASSLIWHAYKSLAVDINWAGFYVTQASEENTLILGPFQGKVACQMIQFGKGVCGTAASTKETQIVPDVNKYPGHIACDGETKSEIVVPIISNDGKTLGVIDIDCLDYEGFDHVDKEFLEKLAKLINKSCVFK | cellular response to oxidative stress cytoplasm; cytosol; nucleus L-methionine-(R)-S-oxide reductase activity Saccharomyces cerevisiae 3D-structure Cytoplasm Nucleus Oxidoreductase Reference proteome Stress response MGSSTGFHHA MGSSTGFHHADHVNYSSNLNKEEILEQLLLSYEGLSDGQVNWVCNLSNASSLIWHAYKSLAVDINWAGFYVTQASEENTLILGPFQGKVACQ... |
budding cell bud growth carbohydrate catabolic process cell wall organization fungal-type cell wall biogenesis | cellular bud; endoplasmic reticulum; plasma membrane; side of membrane | mannan endo-1,6-alpha-mannosidase activity | Saccharomyces cerevisiae | Cell membrane Cell wall biogenesis/degradation Glycoprotein Glycosidase GPI-anchor Hydrolase Lipoprotein Membrane Reference proteome Signal | MLVNKVIGLL | MLVNKVIGLLGVLFATRFTNAVELDLDNYESLQNATSLIAYGLMDYYTGNQYGKTVGMFSDPYYWWEAGGAWGCMLDYWFFMDNDTYNDEIIAAMIHQAGDDNDYIPLNQSTTEGNDDQAFWGIAAMTAAERNFTNPPENEPQWLYLAQAVFNTMALRWDADSCGGGLRWQIFVWNSGYDYKNTVSNGALFHIAARLARYTGNQTYVDWAEKVYEWMVGVNLISNGTYKYVYDGVSIDDNCTKVTSYQWTYNQGLLLAGSAYLYNFTGSDLWHTRTKEFLNASQVFFHDGIVYEAACQGPNSCNTDQRSFKAYFARFLGV... | budding cell bud growth carbohydrate catabolic process cell wall organization fungal-type cell wall biogenesis cellular bud; endoplasmic reticulum; plasma membrane; side of membrane mannan endo-1,6-alpha-mannosidase activity Saccharomyces cerevisiae Cell membrane Cell wall biogenesis/degradation Glycoprotein Glycosida... |
regulation of microtubule nucleation spindle pole body duplication | central plaque of spindle pole body; cytoplasm; intermediate layer of spindle pole body; nucleus | structural constituent of cytoskeleton | Saccharomyces cerevisiae | 3D-structure Coiled coil Cytoplasm Cytoskeleton Nucleus Phosphoprotein Reference proteome | MNGSPTPKRY | MNGSPTPKRYSSKSSRLYDDYYNIPYQYSNPTPMNRDYNDVGSRINADKLVPEEYKRNTEFINKAVQQNKELNFKLREKQNEIFELKKIAETLRSKLEKYVDITKKLEDQNLNLQIKISDLEKKLSDANSTFKEMRFPKVKDPMVDDDPVSENYDQINVPKHRAPDATGNPRTTNKVSNTSDQDSRLKAIERTLSVLTNYVMRSEDGNNDRMSPLPSPLNTILPINNRLNFQEPKRYNPTVKVNPSDDDIMMYESAELKRVEEEIEELKRKILVRKKHDLRKLSLNNQLQELQSMMDGDDNIKLDNVSKHNHATHRHSSQ... | regulation of microtubule nucleation spindle pole body duplication central plaque of spindle pole body; cytoplasm; intermediate layer of spindle pole body; nucleus structural constituent of cytoskeleton Saccharomyces cerevisiae 3D-structure Coiled coil Cytoplasm Cytoskeleton Nucleus Phosphoprotein Reference proteome M... |
ATP export endosome transport via multivesicular body sorting pathway intralumenal vesicle formation late endosome to vacuole transport protein transport ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway | cytoplasm; cytosol; ESCRT III complex; multivesicular body | identical protein binding | Saccharomyces cerevisiae | 3D-structure Endosome Isopeptide bond Membrane Protein transport Reference proteome Transport Ubl conjugation | MDYIKKAIWG | MDYIKKAIWGPDPKEQQRRIRSVLRKNGRNIEKSLRELTVLQNKTQQLIKKSAKKNDVRTVRLYAKELYQINKQYDRMYTSRAQLDSVRMKIDEAIRMNTLSNQMADSAGLMREVNSLVRLPQLRNTMIELEKELMKSGIISEMVDDTMESVGDVGEEMDEAVDEEVNKIVEQYTNEKFKNVDQVPTVELAANEEEQEIPDEKVDEEADRMVNEMRERLRALQN | ATP export endosome transport via multivesicular body sorting pathway intralumenal vesicle formation late endosome to vacuole transport protein transport ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway cytoplasm; cytosol; ESCRT III complex; multivesicular body identical protein... |
protein ubiquitination ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway | Dsc E3 ubiquitin ligase complex; fungal-type vacuole; Golgi apparatus; Golgi membrane | ubiquitin-protein transferase activity zinc ion binding | Saccharomyces cerevisiae | Golgi apparatus Membrane Metal-binding Reference proteome Signal Transferase Transmembrane Transmembrane helix Ubl conjugation pathway Zinc Zinc-finger | MEIDGNTLVF | MEIDGNTLVFIIVILFLFFSSPGGDGVSSQYEFNQLQRLKQQFRTEHNTFVNMTYTDSFRNITGLKLSYQDMLNNPLQNATYPLPGKDYDRWFPNQNYMVLPNDVIEAINTEVWNTSNDDASNLFPPNITSTLLGKIDLVSNNKYEKIRMPVPRFYEPATDFSEDIPPEGETYWSEWPSYGELHNVSFQHGEIAIQISHMSNLQDNNNYLRRNFINKKNDRWKLLNLQIDFSDKAEKEKHSIYSKAVYDIQRGRILSISQSSKFHSLFALPHYMSFQNDYNEKIFNDVKELVDEFWNFTDYTDVMTMKDVQDAYNNANFK... | protein ubiquitination ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway Dsc E3 ubiquitin ligase complex; fungal-type vacuole; Golgi apparatus; Golgi membrane ubiquitin-protein transferase activity zinc ion binding Saccharomyces cerev... |
transcription by RNA polymerase II transcription initiation at RNA polymerase II promoter transcription open complex formation at RNA polymerase II promoter | mitochondrion; nucleus; transcription factor TFIIE complex; transcription preinitiation complex | metal ion binding RNA polymerase II complex binding | Saccharomyces cerevisiae | 3D-structure Direct protein sequencing Metal-binding Nucleus Reference proteome Transcription Transcription regulation Zinc Zinc-finger | MDRPIDDIVK | MDRPIDDIVKNLLKFVVRGFYGGSFVLVLDAILFHSVLAEDDLKQLLSINKTELGPLIARLRSDRLISIHKQREYPPNSKSVERVYYYVKYPHAIDAIKWKVHQVVQRLKDDLDKNSEPNGYMCPICLTKYTQLEAVQLLNFDRTEFLCSLCDEPLVEDDSGKKNKEKQDKLNRLMDQIQPIIDSLKKIDDSRIEENTFEIALARLIPPQNQSHAAYTYNPKKGSTMFRPGDSAPLPNLMGTALGNDSSRRAGANSQATLHINITTASDEVAQRELQERQAEEKRKQNAVPEWHKQSTIGKTALGRLDNEEEFDPVVTAS... | transcription by RNA polymerase II transcription initiation at RNA polymerase II promoter transcription open complex formation at RNA polymerase II promoter mitochondrion; nucleus; transcription factor TFIIE complex; transcription preinitiation complex metal ion binding RNA polymerase II complex binding Saccharomyces c... |
DNA repair mRNA processing nuclear-transcribed mRNA poly(A) tail shortening postreplication repair | cytoplasm; P-body; PAN complex | ATP binding metal ion binding poly(A) binding protein kinase activity RNA binding | Saccharomyces cerevisiae | 3D-structure ATP-binding Coiled coil Cytoplasm Direct protein sequencing Metal-binding mRNA processing Nucleotide-binding Phosphoprotein Reference proteome Zinc Zinc-finger | MDKINPDWAK | MDKINPDWAKDIPCRNITIYGYCKKEKEGCPFKHSDNTTATTINDVPPPIDVGEATTPTMTSVPKFNAKVSASFTPMTVGSDSLTTVTNTTSAATNATGNIAMAATSATASTVNPMINPIVNSSLVNNNNNNSNISISIPTTASSSNYDPFNAPIFTPSSTSSIHTNANAHSFPFPSIANSGGININATDDNSNNMSMANNVPPPMQPPPIESSNLKYPRIYPPPHSLLQYHLYAPEQPSSLKSLLKPNERSADQLFIPNNIREDLTKKNLSILQVFPSSGKVIPSIVQDYFNLVPLNFNNNDFLNKTTLFKVFSNYDGK... | DNA repair mRNA processing nuclear-transcribed mRNA poly(A) tail shortening postreplication repair cytoplasm; P-body; PAN complex ATP binding metal ion binding poly(A) binding protein kinase activity RNA binding Saccharomyces cerevisiae 3D-structure ATP-binding Coiled coil Cytoplasm Direct protein sequencing Metal-bin... |
mRNA 3'-end processing mRNA polyadenylation sno(s)RNA 3'-end processing subtelomeric heterochromatin formation telomere maintenance termination of RNA polymerase II transcription, poly(A)-coupled | chromosome, telomeric region; mRNA cleavage and polyadenylation specificity factor complex; nucleus; Set1C/COMPASS complex | chromatin binding | Saccharomyces cerevisiae | Chromosome mRNA processing Nucleus Reference proteome Repeat Telomere WD repeat | MTTVSINKPN | MTTVSINKPNLLKFKHVKSFQPQEKDCGPVTSLNFDDNGQFLLTSSSNDTMQLYSATNCKFLDTIASKKYGCHSAIFTHAQNECIYSSTMKNFDIKYLNLETNQYLRYFSGHGALVNDLKMNPVNDTFLSSSYDESVRLWDLKISKPQVIIPSLVPNCIAYDPSGLVFALGNPENFEIGLYNLKKIQEGPFLIIKINDATFSQWNKLEFSNNGKYLLVGSSIGKHLIFDAFTGQQLFELIGTRAFPMREFLDSGSACFTPDGEFVLGTDYDGRIAIWNHSDSISNKVLRPQGFIPCVSHETCPRSIAFNPKYSMFVTADE... | mRNA 3'-end processing mRNA polyadenylation sno(s)RNA 3'-end processing subtelomeric heterochromatin formation telomere maintenance termination of RNA polymerase II transcription, poly(A)-coupled chromosome, telomeric region; mRNA cleavage and polyadenylation specificity factor complex; nucleus; Set1C/COMPASS complex c... |
cytoplasmic translation macroautophagy ribosomal large subunit biogenesis | cytosol; cytosolic large ribosomal subunit | RNA binding structural constituent of ribosome | Saccharomyces cerevisiae | 3D-structure Acetylation Cytoplasm Reference proteome Ribonucleoprotein Ribosomal protein | MSTDSIVKAS | MSTDSIVKASNWRLVEVGRVVLIKKGQSAGKLAAIVEIIDQKKVLIDGPKAGVPRQAINLGQVVLTPLTFALPRGARTATVSKKWAAAAVCEKWAASSWAKKIAQRERRAALTDFERFQVMVLRKQKRYTVKKALAKA | cytoplasmic translation macroautophagy ribosomal large subunit biogenesis cytosol; cytosolic large ribosomal subunit RNA binding structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Acetylation Cytoplasm Reference proteome Ribonucleoprotein Ribosomal protein MSTDSIVKAS MSTDSIVKASNWRLVEVGRVVLIKKGQSA... |
inositol phosphoceramide metabolic process sphingolipid biosynthetic process | endoplasmic reticulum; Golgi apparatus; Golgi cisterna membrane; inositol phosphoceramide synthase complex | inositol phosphoceramide synthase activity | Saccharomyces cerevisiae | Glycoprotein Golgi apparatus Lipid metabolism Membrane Phosphoprotein Reference proteome Sphingolipid metabolism Transferase Transmembrane Transmembrane helix | MANPFSRWFL | MANPFSRWFLSERPPNCHVADLETSLDPHQTLLKVQKYKPALSDWVHYIFLGSIMLFVFITNPAPWIFKILFYCFLGTLFIIPATSQFFFNALPILTWVALYFTSSYFPDDRRPPITVKVLPAVETILYGDNLSDILATSTNSFLDILAWLPYGLFHFGAPFVVAAILFVFGPPTVLQGYAFAFGYMNLFGVIMQNVFPAAPPWYKILYGLQSANYDMHGSPGGLARIDKLLGINMYTTAFSNSSVIFGAFPSLHSGCATMEALFFCYCFPKLKPLFIAYVCWLWWSTMYLTHHYFVDLMAGSVLSYVIFQYTKYTHLPI... | inositol phosphoceramide metabolic process sphingolipid biosynthetic process endoplasmic reticulum; Golgi apparatus; Golgi cisterna membrane; inositol phosphoceramide synthase complex inositol phosphoceramide synthase activity Saccharomyces cerevisiae Glycoprotein Golgi apparatus Lipid metabolism Membrane Phosphoprote... |
histone catabolic process positive regulation of proteasomal ubiquitin-dependent protein catabolic process protein polyubiquitination ubiquitin-dependent protein catabolic process | cytoplasm; ubiquitin ligase complex | ubiquitin conjugating enzyme binding ubiquitin protein ligase activity zinc ion binding | Saccharomyces cerevisiae | Metal-binding Reference proteome Repeat Transferase Ubl conjugation pathway Zinc Zinc-finger | MSSGTENDQF | MSSGTENDQFYSFDESDSSSIELYESHNTSEFTIHGLVFPKLISVTSQDSEFDINEDEDGVDTIYEGMLDAPLTKNNKRILCEGSVPNLSYECLTTKGIFERMLQRVDHLQPIFAIPSADILILLQHYDWNEERLLEVWTEKMDELLVELGLSTTANIKKDNDYNSHFREVEFKNDFTCIICCDKKDTETFALECGHEYCINCYRHYIKDKLHEGNIITCMDCSLALKNEDIDKVMGHPSSSKLMDSSIKSFVQKHNRNYKWCPFADCKSIVHLRDTSSLPEYTRLHYSPFVKCNSFHRFCFNCGFEVHSPADCKITTAW... | histone catabolic process positive regulation of proteasomal ubiquitin-dependent protein catabolic process protein polyubiquitination ubiquitin-dependent protein catabolic process cytoplasm; ubiquitin ligase complex ubiquitin conjugating enzyme binding ubiquitin protein ligase activity zinc ion binding Saccharomyces ce... |
endocytosis positive regulation of ubiquitin-dependent endocytosis regulation of intracellular transport ubiquitin-dependent endocytosis | cytoplasm; cytosol; early endosome; late endosome | protein-macromolecule adaptor activity ubiquitin protein ligase binding | Saccharomyces cerevisiae | Cytoplasm Phosphoprotein Reference proteome Ubl conjugation | MLQFNTENDT | MLQFNTENDTVAPVFPMEQDINAAPDAVPLVQTTTLQVFVKLAEPIVFLKGFETNGLSEIAPSILRGSLIVRVLKPNKLKSISITFKGISRTEWPEGIPPKREEFSDVETVVNHTWPFYQADDGMNSFTLEHHSSNNSSNRPSMSDEDYLLEKSGASVYIPPTAEPPKDNSNLSLDAYERNSLSSDNLSNKPVSSDVSHDDSKLLAIQKTPLPSSSRRGSVPANFHGNSLSPHTFISDLFTKTFSNSGATPSPEQEDNYLTPSKDSKEVFIFRPGDYIYTFEQPISQSYPESIKANFGSVEYKLSIDIERFGAFKSTIHT... | endocytosis positive regulation of ubiquitin-dependent endocytosis regulation of intracellular transport ubiquitin-dependent endocytosis cytoplasm; cytosol; early endosome; late endosome protein-macromolecule adaptor activity ubiquitin protein ligase binding Saccharomyces cerevisiae Cytoplasm Phosphoprotein Reference ... |
positive regulation of DNA-templated transcription rescue of stalled ribosome ribosome disassembly ribosome-associated ubiquitin-dependent protein catabolic process | cytoplasm; cytosolic ribosome; mitochondrion; nucleus | K63-linked polyubiquitin modification-dependent protein binding transcription coactivator activity zinc ion binding | Saccharomyces cerevisiae | 3D-structure Cytoplasm Isopeptide bond Phosphoprotein Reference proteome Ubl conjugation | MTRKQAIDYA | MTRKQAIDYAIKQVPQILPLEESDVKALCEQVLSTSSDDPEQIASKFLEFLGHEDLSFEFVMKFNELLNQNDKKEEKKTKNVHLEHTAPTSWKNESKQPTNNYINKKGDEKPKKLKDEKKSSTTRPTVQPSNQSTQSNPIKEKKEHRSKGKLQSLQEIDEAIKMLELRDSGSSKNCNCQGTRHPVFDIAPNCLHCGKVVCVIEGLNKGKCGHCHEQLISDNERTQMVEILNQEKNELNGSSSSLSNASNGANVPKKKTKTYKITSGMGKNLFAEQDKLFDFIERKRERERKRNEVLKLQEEKEESEAKERQASEHDHKAE... | positive regulation of DNA-templated transcription rescue of stalled ribosome ribosome disassembly ribosome-associated ubiquitin-dependent protein catabolic process cytoplasm; cytosolic ribosome; mitochondrion; nucleus K63-linked polyubiquitin modification-dependent protein binding transcription coactivator activity zi... |
cellular response to starvation chromatin organization DNA damage response meiotic cell cycle negative regulation of meiotic nuclear division protein methylation regulation of DNA-templated transcription | nucleus; Rpd3L-Expanded complex; Set3 complex | metal ion binding methylated histone binding | Saccharomyces cerevisiae | 3D-structure Activator Chromatin regulator Meiosis Metal-binding Phosphoprotein Reference proteome Repressor Transcription Transcription regulation Zinc Zinc-finger | MSVPNSKEQS | MSVPNSKEQSLLDDASTLLLFSKGKKRAEEASKIGSKTDTIEHDESHEREKKGAIEMAAAALATASTVSLPLKKATEQSAAEAATSTAAKEETENQPQKQPQWPVPDSYIVDPDAGIITCICDLNDDDGFTIQCDHCNRWQHAICYGIKDIGMAPDDYLCNSCDPREVDINLARKIQQERINVKTVEPSSSNNSASNKNNGRDRASSTTISDVGDSFSTDQDNTNHRDKRRKRNPSNNSIDSKNESASVNSSDGLTSMPKKKEHFLSAKDAYGAIYLPLKDNVFKSDLIEPFLNKHMDDNWVIQYPHKTFKSVSIEVKPY... | cellular response to starvation chromatin organization DNA damage response meiotic cell cycle negative regulation of meiotic nuclear division protein methylation regulation of DNA-templated transcription nucleus; Rpd3L-Expanded complex; Set3 complex metal ion binding methylated histone binding Saccharomyces cerevisiae ... |
chromosome organization maintenance of translational fidelity positive regulation of transcription by RNA polymerase II telomere maintenance telomere maintenance via recombination tRNA modification tRNA threonylcarbamoyladenosine metabolic process tRNA threonylcarbamoyladenosine modification | chromatin; cytoplasm; EKC/KEOPS complex; nucleoplasm; nucleus | chromatin DNA binding metal ion binding N(6)-L-threonylcarbamoyladenine synthase activity | Saccharomyces cerevisiae | Activator Acyltransferase Cytoplasm Metal-binding Nucleus Reference proteome Transcription Transcription regulation Transferase tRNA processing | MVNLNTIPPK | MVNLNTIPPKNGRDYYIALGLEGSANKLGVGIVKHPLLPKHANSDLSYDCEAEMLSNIRDTYVTPPGEGFLPRDTARHHRNWCIRLIKQALAEADIKSPTLDIDVICFTKGPGMGAPLHSVVIAARTCSLLWDVPLVGVNHCIGHIEMGREITKAQNPVVLYVSGGNTQVIAYSEKRYRIFGETLDIAIGNCLDRFARTLKIPNEPSPGYNIEQLAKKAPHKENLVELPYTVKGMDLSMSGILASIDLLAKDLFKGNKKNKILFDKTTGEQKVTVEDLCYSLQENLFAMLVEITERAMAHVNSNQVLIVGGVGCNVRLQE... | chromosome organization maintenance of translational fidelity positive regulation of transcription by RNA polymerase II telomere maintenance telomere maintenance via recombination tRNA modification tRNA threonylcarbamoyladenosine metabolic process tRNA threonylcarbamoyladenosine modification chromatin; cytoplasm; EKC/K... |
autophagy of mitochondrion division septum assembly fungal-type cell wall biogenesis fungal-type cell wall organization polysaccharide catabolic process | cell surface; extracellular region; fungal-type cell wall; mitochondrial inner membrane; mitochondrial outer membrane | hydrolase activity, acting on glycosyl bonds | Saccharomyces cerevisiae | Autophagy Carbohydrate metabolism Cell cycle Cell division Cell wall Cell wall biogenesis/degradation Glycosidase Hydrolase Membrane Mitochondrion Mitochondrion outer membrane Polysaccharide degradation Reference proteome Secreted Septation Signal Stress response | MKLSALLALS | MKLSALLALSASTAVLAAPAVHHSDNHHHNDKRAVVTVTQYVNADGAVVIPAATTATSAAADGKVESVAAATTTLSSTAAAATTSAAASSSSSSSSSSSSSSSVGSGDFEDGTISCSDFPSGQGAVSLDWLGLGGWASIMDMNGNTATSCQDGYYCSYACSPGYAKTQWPSEQPSDGRSVGGLYCKNGKLYRSNTDTNSLCVEGQGSAQAVNKVSGSIAICGTDYPGSENMVVPTVVGAGSSQPINVIKEDSYYQWQGKKTSAQYYVNNAGVSVEDGCIWGTEGSGVGNWAPVVLGAGYTDGITYLSIIPNPNNKEAPNF... | autophagy of mitochondrion division septum assembly fungal-type cell wall biogenesis fungal-type cell wall organization polysaccharide catabolic process cell surface; extracellular region; fungal-type cell wall; mitochondrial inner membrane; mitochondrial outer membrane hydrolase activity, acting on glycosyl bonds Sacc... |
carbohydrate metabolic process ribose phosphate biosynthetic process | cytoplasm; nucleus | oxidoreductase activity sedoheptulose-bisphosphatase activity | Saccharomyces cerevisiae | 3D-structure Carbohydrate metabolism Cytoplasm Hydrolase Nucleus Oxidoreductase Reference proteome | MPSLTPRCII | MPSLTPRCIIVRHGQTEWSKSGQYTGLTDLPLTPYGEGQMLRTGESVFRNNQFLNPDNITYIFTSPRLRARQTVDLVLKPLSDEQRAKIRVVVDDDLREWEYGDYEGMLTREIIELRKSRGLDKERPWNIWRDGCENGETTQQIGLRLSRAIARIQNLHRKHQSEGRASDIMVFAHGHALRYFAAIWFGLGVQKKCETIEEIQNVKSYDDDTVPYVKLESYRHLVDNPCFLLDAGGIGVLSYAHHNIDEPALELAGPFVSPPEEESQHGDV | carbohydrate metabolic process ribose phosphate biosynthetic process cytoplasm; nucleus oxidoreductase activity sedoheptulose-bisphosphatase activity Saccharomyces cerevisiae 3D-structure Carbohydrate metabolism Cytoplasm Hydrolase Nucleus Oxidoreductase Reference proteome MPSLTPRCII MPSLTPRCIIVRHGQTEWSKSGQYTGLTDLPLTP... |
glycogen biosynthetic process | cytoplasm | glycogenin glucosyltransferase activity glycosyltransferase activity metal ion binding UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity | Saccharomyces cerevisiae | Glycogen biosynthesis Glycoprotein Manganese Metal-binding Reference proteome Transferase | MYKKLAIATL | MYKKLAIATLLYSADYLPGVFALGHQVNKLLEEAGKKGDIETCLIVTTSLFNGTLSELAKNILQSIYTKIVLVEPLNCQEESIQKNSENLALLERPELSFALIKARLWELTQFEQVLYLDSDTLPLNKEFLKLFDIMSKQTTSQVGAIADIGWPDMFNSGVMMLIPDADTASVLQNYIFENTSIDGSDQGILNQFFNQNCCTDELVKDSFSREWVQLSFTYNVTIPNLGYQSSPAMNYFKPSIKLIHFIGKHKPWSLWSQKNFIKNEYHDQWNEVYEEFKEEHQLNNEVSKPKISDSDKTETPETITPVDAPPSNEPTTN... | glycogen biosynthetic process cytoplasm glycogenin glucosyltransferase activity glycosyltransferase activity metal ion binding UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity Saccharomyces cerevisiae Glycogen biosynthesis Glycoprotein Manganese Metal-binding Reference proteome Transferase ... |
cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of 5.8S rRNA maturation of LSU-rRNA | cytoplasm; Las1 complex; mitochondrion; nucleolus; nucleus; preribosome, large subunit precursor | endonuclease activity | Saccharomyces cerevisiae | 3D-structure Mitochondrion Nucleus Reference proteome | MIPPRIVPWR | MIPPRIVPWRDFAELEELKLWFYPKSKGTIEDKRQRAVQRVQSYRLKGSQYLPHVVDSTAQITCAVLLDEKEACLGVHQDSIPIRLSYVMALIRFVNGLLDPTQQSQFAIPLHTLAAKIGLPSWFVDLRHWGTHERDLPGLEMLRWAANEALSWLYDHYWNDEELEDDRDDDDDDDDTGYGYRRNDKLEKYMESLTKTLDKWKRLRNEFLEYKWVWENANDSLITSSNFSGDNLVNYDAEKRKSSHASSSETMIRENLRQWQELWKLSIYHNVVLEKFFNNYDPLLLKVLMLNLNNFDWKVIEWVARNYRTQQDDSNITT... | cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of 5.8S rRNA maturation of LSU-rRNA cytoplasm; Las1 complex; mitochondrion; nucleolus; nucleus; preribosome, large subunit precursor endonuclease activity Saccharomyces cerevisiae 3D-structure Mit... |
CDP-diacylglycerol biosynthetic process phospholipid biosynthetic process regulation of triglyceride metabolic process | cytoplasm; endoplasmic reticulum; endoplasmic reticulum membrane; lipid droplet | glycerol-3-phosphate O-acyltransferase activity glycerone-phosphate O-acyltransferase activity sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity | Saccharomyces cerevisiae | Acyltransferase Endoplasmic reticulum Lipid biosynthesis Lipid droplet Lipid metabolism Membrane Phospholipid biosynthesis Phospholipid metabolism Phosphoprotein Reference proteome Transferase Transmembrane Transmembrane helix | MSAPAADHNA | MSAPAADHNAAKPIPHVPQASRRYKNSYNGFVYNIHTWLYDVSVFLFNILFTIFFREIKVRGAYNVPEVGVPTILVCAPHANQFIDPALVMSQTRLLKTSAGKSRSRMPCFVTAESSFKKRFISFFGHAMGGIPVPRIQDNLKPVDENLEIYAPDLKNHPEIIKGRSKNPQTTPVNFTKRFSAKSLLGLPDYLSNAQIKEIPDDETIILSSPFRTSKSKVVELLTNGTNFKYAEKIDNTETFQSVFDHLHTKGCVGIFPEGGSHDRPSLLPIKAGVAIMALGAVAADPTMKVAVVPCGLHYFHRNKFRSRAVLEYGEPIV... | CDP-diacylglycerol biosynthetic process phospholipid biosynthetic process regulation of triglyceride metabolic process cytoplasm; endoplasmic reticulum; endoplasmic reticulum membrane; lipid droplet glycerol-3-phosphate O-acyltransferase activity glycerone-phosphate O-acyltransferase activity sn-1-glycerol-3-phosphate ... |
cellular response to oxidative stress iron-sulfur cluster assembly negative regulation of hydrogen peroxide-mediated programmed cell death negative regulation of nitric oxide biosynthetic process | CIA complex; cytoplasm; cytosol; mitochondrial intermembrane space | 2 iron, 2 sulfur cluster binding 4 iron, 4 sulfur cluster binding electron transfer activity metal ion binding molecular adaptor activity | Saccharomyces cerevisiae | 2Fe-2S 3D-structure 4Fe-4S Cytoplasm Iron Iron-sulfur Metal-binding Mitochondrion Phosphoprotein Reference proteome Ubl conjugation | MSQYKTGLLL | MSQYKTGLLLIHPAVTTTPELVENTKAQAASKKVKFVDQFLINKLNDGSITLENAKYETVHYLTPEAQTDIKFPKKLISVLADSLKPNGSLIGLSDIYKVDALINGFEIINEPDYCWIKMDSSKLNQTVSIPLKKKKTNNTKLQSGSKLPTFKKASSSTSNLPSFKKADHSRQPIVKETDSFKPPSFKMTTEPKVYRVVDDLIEDSDDDDFSSDSSKAQYFDQVDTSDDSIEEEELIDEDGSGKSMITMITCGKSKTKKKKACKDCTCGMKEQEENEINDIRSQQDKVVKFTEDELTEIDFTIDGKKVGGCGSCSLGDAF... | cellular response to oxidative stress iron-sulfur cluster assembly negative regulation of hydrogen peroxide-mediated programmed cell death negative regulation of nitric oxide biosynthetic process CIA complex; cytoplasm; cytosol; mitochondrial intermembrane space 2 iron, 2 sulfur cluster binding 4 iron, 4 sulfur cluster... |
cell wall organization glutathione metabolic process | cytoplasm | glutathione dehydrogenase (ascorbate) activity glutathione transferase activity | Saccharomyces cerevisiae | 3D-structure Cell wall biogenesis/degradation Cytoplasm Oxidoreductase Reference proteome Transferase | MSKQWASGTN | MSKQWASGTNGAFKRQVSSFRETISKQHPIYKPAKGRYWLYVSLACPWAHRTLITRALKGLTSVIGCSVVHWHLDEKGWRFLDMEKQLEDSEDFLEHWHDVAGGIRTAKEDSSKSFAEIKNDSQRFMVDATNEPHYGYKRISDLYYKSDPQYSARFTVPVLWDLETQTIVNNESSEIIRILNSSAFDEFVDDDHKKTDLVPAQLKTQIDDFNSWVYDSINNGVYKTGFAEKAEVYESEVNNVFEHLDKVEKILSDKYSKLKAKYGEEDRQKILGEFFTVGDQLTEADIRLYTTVIRFDPVYVQHFKCNFTSIRAGYPFIH... | cell wall organization glutathione metabolic process cytoplasm glutathione dehydrogenase (ascorbate) activity glutathione transferase activity Saccharomyces cerevisiae 3D-structure Cell wall biogenesis/degradation Cytoplasm Oxidoreductase Reference proteome Transferase MSKQWASGTN MSKQWASGTNGAFKRQVSSFRETISKQHPIYKPAKGRY... |
assembly of large subunit precursor of preribosome maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosomal large subunit assembly | nucleolus; preribosome, large subunit precursor | 5S rRNA binding 7S RNA binding rRNA binding | Saccharomyces cerevisiae | 3D-structure Nucleus Phosphoprotein Reference proteome | MIRTVKPKNA | MIRTVKPKNARAKRALVKREAKLVENVKQALFIPGQSCNKNLHDIMVDLSALKKPDMKRFNRKNDIHPFEDMSPLEFFSEKNDCSLMVLMTSSKKRKNNMTFIRTFGYKIYDMIELMVADNFKLLSDFKKLTFTVGLKPMFTFQGAAFDTHPVYKQIKSLFLDFFRGESTDLQDVAGLQHVISMTIQGDFQDGEPLPNVLFRVYKLKSYKSDQGGKRLPRIELVEIGPRLDFKIGRIHTPSPDMVTEAHKKPKQLEMKTKKNVELDIMGDKLGRIHMGKQDLGKLQTRKMKGLKSKFDQGTEEGDGEVDEDYEDEASYSD... | assembly of large subunit precursor of preribosome maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosomal large subunit assembly nucleolus; preribosome, large subunit precursor 5S rRNA b... |
mitochondrial protein catabolic process mitochondrial protein processing mitochondrial respiratory chain complex assembly protein quality control for misfolded or incompletely synthesized proteins TOR signaling | mitochondrial inner membrane; mitochondrion | metal ion binding metalloendopeptidase activity | Saccharomyces cerevisiae | Disulfide bond Hydrolase Membrane Metal-binding Metalloprotease Mitochondrion Mitochondrion inner membrane Protease Reference proteome Thioester bond Transmembrane Transmembrane helix Zinc | MLRNIIRFKG | MLRNIIRFKGFGKGTSGGFLKPVSFRVQLTRCYRYDNGPSYRRFNNGEYSQKSSFKSILLDKSSRKYLALLFGGCSLFYYTHLDKAPVSDRSRFIWVSRPLELTIGNYTYKSIWRQTQQEILPPQHPLSIKIENIFMKIVEAAYKDPSVDNSLLDGIKWEIHVVNDPTASPNAFVLPGGKVFIFSSILPICANDDGIATVLAHEFAHQLARHTAENLSKAPIYSLLGLVLYTVTGAHAINNILLDGFLRMPASRQMETEADYIGLMIMSRACFQPQESIKVWERMANFEKQMNRGGVVNMEFLSTHPASTRRIENMSKWL... | mitochondrial protein catabolic process mitochondrial protein processing mitochondrial respiratory chain complex assembly protein quality control for misfolded or incompletely synthesized proteins TOR signaling mitochondrial inner membrane; mitochondrion metal ion binding metalloendopeptidase activity Saccharomyces cer... |
cell budding phospholipid metabolic process sporulation resulting in formation of a cellular spore triglyceride catabolic process triglyceride mobilization | lipid droplet | calcium-independent phospholipase A2 activity lysophosphatidic acid acyltransferase activity sterol esterase activity triglyceride lipase activity | Saccharomyces cerevisiae | Hydrolase Lipid degradation Lipid droplet Lipid metabolism Phosphoprotein Reference proteome Sporulation | MSSKISDLTS | MSSKISDLTSTQNKPLLVTQQLIEKYYEQILGTSQNIIPILNPKNKFIRPSKDNSDVERVEEDAGKRLQTGKNKTTNKVNFNLDTGNEDKLDDDQETVTENENNDIEMVETDEGEDERQGSSLASKCKSFLYNVFVGNYERDILIDKVCSQKQHAMSFEEWCSAGARLDDLTGKTEWKQKLESPLYDYKLIKDLTSRMREERLNRNYAQLLYIIRTNWVRNLGNMGNVNLYRHSHVGTKYLIDEYMMESRLALESLMESDLDDSYLLGILQQTRRNIGRTALVLSGGGTFGLFHIGVLGTLFELDLLPRVISGSSAGAIV... | cell budding phospholipid metabolic process sporulation resulting in formation of a cellular spore triglyceride catabolic process triglyceride mobilization lipid droplet calcium-independent phospholipase A2 activity lysophosphatidic acid acyltransferase activity sterol esterase activity triglyceride lipase activity Sac... |
autophagy centriole replication centrosome cycle chromosome segregation negative regulation of hippo signaling negative regulation of insulin receptor signaling pathway negative regulation of smoothened signaling pathway positive regulation of Toll signaling pathway protein dephosphorylation receptor guanylyl cyclase s... | centriole; cytoplasm; cytosol; FAR/SIN/STRIPAK complex; nucleoplasm; protein phosphatase type 2A complex | protein phosphatase regulator activity | Drosophila melanogaster | Acetylation Reference proteome Repeat | MAASDKSVDD | MAASDKSVDDSLYPIAVLIDELKNEDVQLRLNSIKKLSTIALALGEERTRSELIPFLTETIYDEDEVLLALADQLGNFTSLVGGPEFAMYLIPPLESLATVEETVVRDKAVESLRTVAAEHSAQDLEIHVVPTLQRLVSGDWFTSRTSACGLFSVCYPRVTQPVKAELRANFRKLCQDETPMVRRAAANKLGEFAKVVETEYLKSDLIPNFVQLAQDDQDSVRLLAVEACVSIAQLLPQDDVEHLVLPTLRQCASDSSWRVRYMVAEKFVDLQKAVGPEITRVDLVPAFQYLLKDAEAEVRAAVATKVKDFCANLDKVNQ... | autophagy centriole replication centrosome cycle chromosome segregation negative regulation of hippo signaling negative regulation of insulin receptor signaling pathway negative regulation of smoothened signaling pathway positive regulation of Toll signaling pathway protein dephosphorylation receptor guanylyl cyclase s... |
adult somatic muscle development cardiac muscle tissue development heart contraction heart development muscle cell cellular homeostasis muscle contraction muscle organ development myofibril assembly nervous system development nuclear division sarcomere organization | striated muscle thin filament; troponin complex | actin binding | Drosophila melanogaster | Acetylation Actin-binding Alternative splicing Methylation Muscle protein Reference proteome | MADDEKKAAA | MADDEKKAAAPAAAPAAAAKPAAPAAAPAANGKAAPAANGKAAPAAAAAPAGPPKDPNDPKVKAEEAKKAKQAEIERKRAEVRKRMEEASKAKKAKKGFMTPERKKKLRLLLRKKAAEELKKEQERKAAERRRIIEERCGSPRNLSDASEGELQEICEEYYERMYICEGQKWDLEYEVRKKDWEINDLNAQVNDLRGKFVKPALKKVSKYENKFAKLQKKAAEFNFRNQLKVVKKKEFTLEEEEKEKKPDWSKGKPGDAKVKEEVEAEA | adult somatic muscle development cardiac muscle tissue development heart contraction heart development muscle cell cellular homeostasis muscle contraction muscle organ development myofibril assembly nervous system development nuclear division sarcomere organization striated muscle thin filament; troponin complex actin ... |
anatomical structure formation involved in morphogenesis axon extension axon guidance brain development cerebral cortex development dorsal/ventral pattern formation hair follicle development maintenance of epithelial cell apical/basal polarity mesoderm development negative regulation of gene expression, epigenetic nega... | nucleus | chromatin binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA... | Rattus norvegicus | Activator DNA-binding Homeobox LIM domain Metal-binding Nucleus Reference proteome Repeat Transcription Transcription regulation Zinc | MLFHSLSGPE | MLFHSLSGPEVHGVIDEMDRRQERGSGISSAIDRGDTETTMPSISSDRAALCAGCGGKISDRYYLLAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIYCKEDYYRRFSVQRCARCHLGISESEMVMRARDLVYHLNCFTCTTCNKMLTTGDHFGMKDSLVYCRLHFEALLQGEYPPHFNHADVARAAAAAEQLRVQDWAQLGLTLGLPYYNGVGTVQKGRPRKRKSPGPGADLAAYNAALSCNENDAEHLDRDQPYPSSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFR... | anatomical structure formation involved in morphogenesis axon extension axon guidance brain development cerebral cortex development dorsal/ventral pattern formation hair follicle development maintenance of epithelial cell apical/basal polarity mesoderm development negative regulation of gene expression, epigenetic nega... |
actin cytoskeleton organization excitatory chemical synaptic transmission heart development muscle structure development positive regulation of stress fiber assembly | actin cytoskeleton; adherens junction; cytoplasm; cytoskeleton; dendritic spine; early endosome lumen; early endosome membrane; filamentous actin; lamellipodium; nucleus; perinuclear region of cytoplasm; postsynaptic membrane; recycling endosome lumen; recycling endosome membrane; stress fiber; Z disc | actin binding actinin binding alpha-actinin binding metal ion binding muscle alpha-actinin binding protein homodimerization activity protein phosphatase binding | Rattus norvegicus | Cell projection Cytoplasm Cytoskeleton Endosome LIM domain Membrane Metal-binding Nucleus Phosphoprotein Reference proteome Synapse Synaptosome Zinc | MTHAVTLRGP | MTHAVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDSIQAINGESTELMTHLEAQNRIKGCHDHLTLSVSRPENKNWPSSPNDKAQAHRIHIDPEAQDGSPATSRRSSISGISLEDNRSGLGSPYGQPPRLPVPHNGSSNEVTLPSQMSALHVSPPPSADTPRILPRNRDCRVDLGSEVYRMLREPAEPAASEPKQSGSFRYLQGMLEAGEGGDRPGSGGSRNLKPAASKLGAPLSGLQGLPECTRCGHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGYFFLDERLYCENHAKARVKPPEGYDVVA... | actin cytoskeleton organization excitatory chemical synaptic transmission heart development muscle structure development positive regulation of stress fiber assembly actin cytoskeleton; adherens junction; cytoplasm; cytoskeleton; dendritic spine; early endosome lumen; early endosome membrane; filamentous actin; lamelli... |
fatty acid biosynthetic process gluconeogenesis glycolytic process phosphorylation | cytosol | ADP binding ATP binding phosphoglycerate kinase activity triose-phosphate isomerase activity | Thermotoga maritima | 3D-structure ATP-binding Cytoplasm Fatty acid biosynthesis Fatty acid metabolism Gluconeogenesis Glycolysis Isomerase Kinase Lipid biosynthesis Lipid metabolism Multifunctional enzyme Nucleotide-binding Reference proteome Transferase | MEKMTIRDVD | MEKMTIRDVDLKGKRVIMRVDFNVPVKDGVVQDDTRIRAALPTIKYALEQGAKVILLSHLGRPKGEPSPEFSLAPVAKRLSELLGKEVKFVPAVVGDEVKKAVEELKEGEVLLLENTRFHPGETKNDPELAKFWASLADIHVNDAFGTAHRAHASNVGIAQFIPSVAGFLMEKEIKFLSKVTYNPEKPYVVVLGGAKVSDKIGVITNLMEKADRILIGGAMMFTFLKALGKEVGSSRVEEDKIDLAKELLEKAKEKGVEIVLPVDAVIAQKIEPGVEKKVVRIDDGIPEGWMGLDIGPETIELFKQKLSDAKTVVWNGPM... | fatty acid biosynthetic process gluconeogenesis glycolytic process phosphorylation cytosol ADP binding ATP binding phosphoglycerate kinase activity triose-phosphate isomerase activity Thermotoga maritima 3D-structure ATP-binding Cytoplasm Fatty acid biosynthesis Fatty acid metabolism Gluconeogenesis Glycolysis Isomeras... |
xylan catabolic process | extracellular region | endo-1,4-beta-xylanase activity | Hypocrea jecorina | 3D-structure Carbohydrate metabolism Direct protein sequencing Glycoprotein Glycosidase Hydrolase Polysaccharide degradation Pyrrolidone carboxylic acid Secreted Signal Xylan degradation | MVSFTSLLAG | MVSFTSLLAGVAAISGVLAAPAAEVESVAVEKRQTIQPGTGYNNGYFYSYWNDGHGGVTYTNGPGGQFSVNWSNSGNFVGGKGWQPGTKNKVINFSGSYNPNGNSYLSVYGWSRNPLIEYYIVENFGTYNPSTGATKLGEVTSDGSVYDIYRTQRVNQPSIIGTATFYQYWSVRRNHRSSGSVNTANHFNAWAQQGLTLGTMDYQIVAVEGYFSSGSASITVS | xylan catabolic process extracellular region endo-1,4-beta-xylanase activity Hypocrea jecorina 3D-structure Carbohydrate metabolism Direct protein sequencing Glycoprotein Glycosidase Hydrolase Polysaccharide degradation Pyrrolidone carboxylic acid Secreted Signal Xylan degradation MVSFTSLLAG MVSFTSLLAGVAAISGVLAAPAAEVE... |
xylan catabolic process | extracellular region | endo-1,4-beta-xylanase activity | Hypocrea jecorina | 3D-structure Carbohydrate metabolism Direct protein sequencing Glycoprotein Glycosidase Hydrolase Polysaccharide degradation Secreted Signal Xylan degradation | MVAFSSLICA | MVAFSSLICALTSIASTLAMPTGLEPESSVNVTERGMYDFVLGAHNDHRRRASINYDQNYQTGGQVSYSPSNTGFSVNWNTQDDFVVGVGWTTGSSAPINFGGSFSVNSGTGLLSVYGWSTNPLVEYYIMEDNHNYPAQGTVKGTVTSDGATYTIWENTRVNEPSIQGTATFNQYISVRNSPRTSGTVTVQNHFNAWASLGLHLGQMNYQVVAVEGWGGSGSASQSVSN | xylan catabolic process extracellular region endo-1,4-beta-xylanase activity Hypocrea jecorina 3D-structure Carbohydrate metabolism Direct protein sequencing Glycoprotein Glycosidase Hydrolase Polysaccharide degradation Secreted Signal Xylan degradation MVAFSSLICA MVAFSSLICALTSIASTLAMPTGLEPESSVNVTERGMYDFVLGAHNDHRRRASI... |
microtubule-based process | cytoplasm; microtubule | GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton | Torpedo marmorata | Acetylation Cytoplasm Cytoskeleton GTP-binding Hydrolase Isopeptide bond Magnesium Metal-binding Microtubule Nucleotide-binding | MRECISIHVG | MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVSEITNACFEPANQMVKCDPRHGKYMACCLLYR... | microtubule-based process cytoplasm; microtubule GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton Torpedo marmorata Acetylation Cytoplasm Cytoskeleton GTP-binding Hydrolase Isopeptide bond Magnesium Metal-binding Microtubule Nucleotide-binding MRECISIHVG MRECISIHVGQAGVQIGNACWELYCL... |
activation of NF-kappaB-inducing kinase activity apoptotic process carbohydrate metabolic process cartilage development cellular response to tumor necrosis factor chitin catabolic process inflammatory response lung development positive regulation of angiogenesis positive regulation of ERK1 and ERK2 cascade positive reg... | cytoplasm; endoplasmic reticulum; extracellular exosome; extracellular matrix; extracellular region; extracellular space; perinuclear region of cytoplasm; specific granule lumen | carbohydrate binding chitin binding extracellular matrix structural constituent | Homo sapiens | 3D-structure Antimicrobial Apoptosis Asthma Cytoplasm Direct protein sequencing Disulfide bond Endoplasmic reticulum Glycoprotein Inflammatory response Lectin Reference proteome Schizophrenia Secreted Signal | MGVKASQTGF | MGVKASQTGFVVLVLLQCCSAYKLVCYYTSWSQYREGDGSCFPDALDRFLCTHIIYSFANISNDHIDTWEWNDVTLYGMLNTLKNRNPNLKTLLSVGGWNFGSQRFSKIASNTQSRRTFIKSVPPFLRTHGFDGLDLAWLYPGRRDKQHFTTLIKEMKAEFIKEAQPGKKQLLLSAALSAGKVTIDSSYDIAKISQHLDFISIMTYDFHGAWRGTTGHHSPLFRGQEDASPDRFSNTDYAVGYMLRLGAPASKLVMGIPTFGRSFTLASSETGVGAPISGPGIPGRFTKEAGTLAYYEICDFLRGATVHRILGQQVPYAT... | activation of NF-kappaB-inducing kinase activity apoptotic process carbohydrate metabolic process cartilage development cellular response to tumor necrosis factor chitin catabolic process inflammatory response lung development positive regulation of angiogenesis positive regulation of ERK1 and ERK2 cascade positive reg... |
amino acid metabolic process fatty acid metabolic process glutathione biosynthetic process glutathione catabolic process inflammatory response leukotriene D4 biosynthetic process proteolysis | plasma membrane | glutathione hydrolase activity leukotriene C4 gamma-glutamyl transferase activity leukotriene-C(4) hydrolase peptidyltransferase activity | Homo sapiens | Acyltransferase Alternative splicing Glutathione biosynthesis Glycoprotein Hydrolase Leukotriene biosynthesis Membrane Protease Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix Zymogen | MARGYGATVS | MARGYGATVSLVLLGLGLALAVIVLAVVLSRHQAPCGPQAFAHAAVAADSKVCSDIGRAILQQQGSPVDATIAALVCTSVVNPQSMGLGGGVIFTIYNVTTGKVEVINARETVPASHAPSLLDQCAQALPLGTGAQWIGVPGELRGYAEAHRRHGRLPWAQLFQPTIALLRGGHVVAPVLSRFLHNSILRPSLQASTLRQLFFNGTEPLRPQDPLPWPALATTLETVATEGVEVFYTGRLGQMLVEDIAKEGSQLTLQDLAKFQPEVVDALEVPLGDYTLYSPPPPAGGAILSFILNVLRGFNFSTESMARPEGRVNVYH... | amino acid metabolic process fatty acid metabolic process glutathione biosynthetic process glutathione catabolic process inflammatory response leukotriene D4 biosynthetic process proteolysis plasma membrane glutathione hydrolase activity leukotriene C4 gamma-glutamyl transferase activity leukotriene-C(4) hydrolase pept... |
energy homeostasis NADPH oxidation negative regulation of fatty acid oxidation organic acid metabolic process response to lipopolysaccharide taurine biosynthetic process toxin metabolic process xenobiotic metabolic process | endoplasmic reticulum membrane | flavin adenine dinucleotide binding hypotaurine dehydrogenase activity monooxygenase activity N,N-dimethylaniline monooxygenase activity NADP binding trimethylamine monooxygenase activity | Rattus norvegicus | Direct protein sequencing Endoplasmic reticulum FAD Flavoprotein Membrane Monooxygenase NADP Oxidoreductase Reference proteome Transmembrane Transmembrane helix | MVKRVAIVGA | MVKRVAIVGAGVSGLASIKCCLEEGLEPTCFERSCDLGGLWRFTEHVEEGRASLYNSVVSNSSKEMSCYSDFPFPEDYPNFVPNSLFLEYLQLYATQFNLLRCIYFNTKVCSITKRPDFAVSGQWEVVTVCQGKQSSDTFDAVMVCTGFLTNPHLPLDSFPGIQTFKGQYFHSRQYKHPDVFKDKRVLVVGMGNSGTDIAVEASHLAKKVFLSTTGGAWVISRVFDSGYPWDMIFMTRFQNMLRNLLPTPVVSWLISKKMNSWFNHVNYGVAPEDRTQLREPVLNDELPGRIITGKVLIKPSIKEVKENSVVFNNTPKEE... | energy homeostasis NADPH oxidation negative regulation of fatty acid oxidation organic acid metabolic process response to lipopolysaccharide taurine biosynthetic process toxin metabolic process xenobiotic metabolic process endoplasmic reticulum membrane flavin adenine dinucleotide binding hypotaurine dehydrogenase acti... |
regulation of systemic arterial blood pressure zymogen activation | acrosomal vesicle; apical part of cell; extracellular space; nucleus; secretory granule | endopeptidase activity peptidase activity serine-type endopeptidase activity serine-type peptidase activity | Mus musculus | 3D-structure Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Serine protease Signal Zymogen | MWFLILFLAL | MWFLILFLALSLGGIDAAPPLQSRVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA | regulation of systemic arterial blood pressure zymogen activation acrosomal vesicle; apical part of cell; extracellular space; nucleus; secretory granule endopeptidase activity peptidase activity serine-type endopeptidase activity serine-type peptidase activity Mus musculus 3D-structure Direct protein sequencing Disulf... |
brain renin-angiotensin system regulation of systemic arterial blood pressure zymogen activation | acrosomal vesicle; apical part of cell; extracellular space; nucleus; protein-containing complex; secretory granule | endopeptidase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides peptidase activity serine-type endopeptidase activity serine-type peptidase activity | Mus musculus | Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Serine protease Signal Zymogen | MWFLILFPAL | MWFLILFPALSLGGIDAAPPLQSRVVGGFNCEKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTTPPGADFSNDLMLLRLSKPADITDVVKPIALPTKEPKPGSTCLASGWGSITPTRWQKSDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGGGKDTCAGDSGGPLICDGILQGTTSNGPEPCGKPGVPAIYTNLIKFNSWIKDTMMKNA | brain renin-angiotensin system regulation of systemic arterial blood pressure zymogen activation acrosomal vesicle; apical part of cell; extracellular space; nucleus; protein-containing complex; secretory granule endopeptidase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear ami... |
adaptive immune response antigen processing and presentation of endogenous peptide antigen via MHC class I cytosol to endoplasmic reticulum transport defense response peptide antigen transport peptide transport protection from natural killer cell mediated cytotoxicity protein transport transmembrane transport | endoplasmic reticulum membrane; membrane; MHC class I peptide loading complex; TAP complex | ABC-type peptide antigen transporter activity ADP binding ATP binding ATP hydrolysis activity metal ion binding MHC class I protein binding MHC class Ib protein binding nucleotide binding peptide antigen binding peptide transmembrane transporter activity protein homodimerization activity protein-containing complex bind... | Rattus norvegicus | 3D-structure Adaptive immunity ATP-binding Endoplasmic reticulum Immunity Magnesium Membrane Metal-binding Nucleotide-binding Peptide transport Protein transport Reference proteome Translocase Transmembrane Transmembrane helix Transport | MAAHAWPTAA | MAAHAWPTAALLLLLVDWLLLRPVLPGIFSLLVPEVPLLRVWAVGLSRWAILGLGVRGVLGVTAGARGWLAALQPLVAALGLALPGLASFRKLSAWGALREGDNAGLLHWNSRLDAFVLSYVAALPAAALWHKLGGFWAPSGHKGAGDMLCRMLGFLDSKKGRLHLVLVLLILSCLGEMAIPFFTGRITDWILQDKTAPSFARNMWLMCILTIASTVLEFAGDGIYNITMGHMHSRVHGEVFRAVLHQETGFFLKNPTGSITSRVTEDTSNVCESISDKLNLFLWYLGRGLCLLAFMIWGSFYLTVVTLLSLPLLFLLPR... | adaptive immune response antigen processing and presentation of endogenous peptide antigen via MHC class I cytosol to endoplasmic reticulum transport defense response peptide antigen transport peptide transport protection from natural killer cell mediated cytotoxicity protein transport transmembrane transport endoplasm... |
antigen processing and presentation of endogenous peptide antigen via MHC class I antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent antigen proce... | endoplasmic reticulum; endoplasmic reticulum membrane; membrane; MHC class I peptide loading complex; nuclear speck; TAP complex | ABC-type peptide antigen transporter activity ABC-type peptide transporter activity ADP binding ATP binding ATP hydrolysis activity identical protein binding metal ion binding MHC class I protein binding MHC class Ib protein binding nucleotide binding peptide antigen binding protein homodimerization activity protein-co... | Mus musculus | Adaptive immunity ATP-binding Endoplasmic reticulum Immunity Magnesium Membrane Metal-binding Nucleotide-binding Peptide transport Protein transport Reference proteome Translocase Transmembrane Transmembrane helix Transport | MALSYLRPWV | MALSYLRPWVSLLLADMALLGLLQGSLGNLLPQGLPGLWIEGTLRLGVLWGLLKVGELLGLVGTLLPLLCLATPLFFSLRALVGGTASTSVVRVASASWGWLLAGYGAVALSWAVWAVLSPAGVQEKEPGQENRTLMKRLLKLSRPDLPFLIAAFFFLVVAVWGETLIPRYSGRVIDILGGDFDPDAFASAIFFMCLFSVGSSFSAGCRGGSFLFTMSRINLRIREQLFSSLLRQDLGFFQETKTGELNSRLSSDTSLMSRWLPFNANILLRSLVKVVGLYFFMLQVSPRLTFLSLLDLPLTIAAEKVYNPRHQAVLKEI... | antigen processing and presentation of endogenous peptide antigen via MHC class I antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent antigen proce... |
antigen processing and presentation of endogenous peptide antigen via MHC class I antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent antigen proce... | endoplasmic reticulum membrane; membrane; MHC class I peptide loading complex; TAP complex | ABC-type peptide antigen transporter activity ABC-type peptide transporter activity ADP binding ATP binding ATP hydrolysis activity identical protein binding metal ion binding MHC class I protein binding MHC class Ib protein binding nucleotide binding peptide antigen binding protein homodimerization activity protein-co... | Rattus norvegicus | Adaptive immunity ATP-binding Endoplasmic reticulum Immunity Magnesium Membrane Metal-binding Nucleotide-binding Peptide transport Protein transport Reference proteome Translocase Transmembrane Transmembrane helix Transport | MALSHPRPWA | MALSHPRPWASLLLVDLALLGLLQSSLGTLLPPGLPGLWLEGTLRLGVLWGLLKVGGLLRLVGTFLPLLCLTNPLFFSLRALVGSTMSTSVVRVASASWGWLLADYGAVALSLAVWAVLSPAGAQEKEPGQENNRALMIRLLRLSKPDLPFLIVAFIFLAMAVWWEMFIPHYSGRVIDILGGDFDPDAFASAIFFMCLFSVGSSLSAGCRGGSFLFAESRINLRIREQLFSSLLRQDLAFFQETKTGELNSRLSSDTSLMSQWLSLNANILLRSLVKVVGLYYFMLQVSPRLTFLSLLDLPLTIAAEKVYNPRHQAVLKE... | antigen processing and presentation of endogenous peptide antigen via MHC class I antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent antigen proce... |
positive regulation of antibacterial peptide production regulation of systemic arterial blood pressure zymogen activation | cornified envelope; epidermal lamellar body; extracellular space; secretory granule | peptidase activity serine-type endopeptidase activity | Rattus norvegicus | Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Serine protease Signal Zymogen | MWFLILFLDL | MWFLILFLDLSLGQIDAAPPGQSRVIGGYKCEKNSQPWQVALYSFTKYLCGGVLIDPSWVITAAHCSSNNYQVWLGRNNLLEDEPFAQHRLVSQSFPHPDYKPFLMRNHTRKPGDDHSNDLMLLHLSQPADITDGVKVIDLPTEEPKVGSTCLASGWGSTKPLIWEFPDDLQCVNIHLLSNEKCIKAYKEKVTDLMLCAGELEGGKDTCTGDSGGPLLCDGVLQGITSWGSVPCAKTNMPAIYTKLIKFTSWIKEVMKENP | positive regulation of antibacterial peptide production regulation of systemic arterial blood pressure zymogen activation cornified envelope; epidermal lamellar body; extracellular space; secretory granule peptidase activity serine-type endopeptidase activity Rattus norvegicus Direct protein sequencing Disulfide bond G... |
regulation of systemic arterial blood pressure zymogen activation | secretory granule | serine-type endopeptidase activity | Rattus norvegicus | Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Serine protease Signal Zymogen | MWFLILFLAL | MWFLILFLALSLGGIDAAPPGQSRIVGGYKCEKNSQPWQVAIINEYLCGGVLIDPSWVITAAHCYSNYYHVLLGRNNLFEDEPFAQYRFVNQSFPHPDYKPFLMRNHTRQRGDDYSNDLMLLHLSEPADITDGVKVIDLPTEEPKVGSTCLASGWGSTKPLNWELPDDLQCVNIHLLSNEKCIEAYEQKVTDLMLCAGEMDGRKDTCKGDSGGPLICDGVLQGITSWGNVPCAEPYNPGVYTKLIKFTSWIKEVMKENP | regulation of systemic arterial blood pressure zymogen activation secretory granule serine-type endopeptidase activity Rattus norvegicus Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Serine protease Signal Zymogen MWFLILFLAL MWFLILFLALSLGGIDAAPPGQSRIVGGYKCEKNSQPWQVAIINEYLCG... |
cell-cell signaling gap junction-mediated intercellular transport | connexin complex; plasma membrane | gap junction channel activity | Gallus gallus | Cell junction Cell membrane Disulfide bond Gap junction Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix | MGDWSFLGNI | MGDWSFLGNILEQVNEQSTVIGRVWLTVLFIFRILILGTAAELVWGDEQSDFVCNTQQPGCENVCYDEAFPISHIRLWVLQIIFVSTPSLVYFGHAVHHVRMEEKRKEREEAERRQQAEVDEEKLPLAPNQNKGNNPDGTKKFRLEGTLLRTYILHIIFKTLFEVGFIVGQYFLYGFRILPLYRCGRWPCPNLVDCFVSRPTEKTIFIMFMLVVAAVSLFLNLVEISHLILKRIRRALRRPAEEQMGEVPEKPLHAIAVSSIPKAKGYKLLEEEKPVSHYFPLTEVGVEPSPLPSAFNEFEEKIGMGPLEDLSRAFDERL... | cell-cell signaling gap junction-mediated intercellular transport connexin complex; plasma membrane gap junction channel activity Gallus gallus Cell junction Cell membrane Disulfide bond Gap junction Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix MGDWSFLGNI MGDWSFLGNILEQVNEQSTVIGRVWLTVLFIF... |
atrial cardiac muscle cell action potential AV node cell to bundle of His cell communication by electrical coupling cardiac muscle tissue development cell development cell-cell junction assembly cell-cell signaling chemical synaptic transmission gap junction assembly muscle contraction SA node cell to atrial cardiac mu... | connexin complex; endoplasmic reticulum; endoplasmic reticulum membrane; gap junction; intercalated disc; nucleoplasm; plasma membrane; synapse | gap junction channel activity gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling monoatomic ion channel activity | Homo sapiens | 3D-structure Cell junction Cell membrane Gap junction Membrane Reference proteome Transmembrane Transmembrane helix | MSWSFLTRLL | MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGCENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMRWKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDGLMKIYVLQLLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTGLCLLLNIWEMLHLGFGTIRDSLNSKRRELEDPGAYNYPFTWNTPSAPPGYNIAVKPDQIQYTELSNAKIAYKQNKANTAQ... | atrial cardiac muscle cell action potential AV node cell to bundle of His cell communication by electrical coupling cardiac muscle tissue development cell development cell-cell junction assembly cell-cell signaling chemical synaptic transmission gap junction assembly muscle contraction SA node cell to atrial cardiac mu... |
anatomical structure morphogenesis cell differentiation male gonad development male sex determination negative regulation of gene expression negative regulation of transcription by RNA polymerase II positive regulation of DNA-templated transcription positive regulation of gene expression positive regulation of male gon... | cytoplasm; nuclear speck; nucleus; transcription regulator complex | calmodulin binding DNA binding DNA binding, bending DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor binding enzyme binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding | Rattus norvegicus | Acetylation Activator Calmodulin-binding Cytoplasm Differentiation DNA-binding Nucleus Reference proteome Repressor Sexual differentiation Transcription Transcription regulation | MEGHVKRPMN | MEGHVKRPMNAFMVWSRGERRKLAQQNPSMQNSEISKHLGYQWKSLTEAEKRPFFQEAQRLKTLHREKYPNYKYQPHRRVKVPQRSYTLQREVASTKLYNLLQWDNNLHTIIYGQDWARAAHQSSKNQKSIYLQPVDIPTGYPLQQKQQHQQQQHVHLQQQQQQQHQFH | anatomical structure morphogenesis cell differentiation male gonad development male sex determination negative regulation of gene expression negative regulation of transcription by RNA polymerase II positive regulation of DNA-templated transcription positive regulation of gene expression positive regulation of male gon... |
auxin-activated signaling pathway protein transport regulation of auxin metabolic process response to brefeldin A vesicle-mediated transport to the plasma membrane | cytosol; early endosome; Golgi apparatus; trans-Golgi network | GTP binding GTPase activity mRNA binding phospholipase activator activity | Arabidopsis thaliana | 3D-structure Auxin signaling pathway Endosome ER-Golgi transport Golgi apparatus GTP-binding Hydrolase Lipoprotein Myristate Nucleotide-binding Protein transport Reference proteome Transport | MGLSFGKLFS | MGLSFGKLFSRLFAKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRDRVVEARDELHRMLNEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRQRHWYIQSTCATSGEGLYEGLDWLSNNIASKA | auxin-activated signaling pathway protein transport regulation of auxin metabolic process response to brefeldin A vesicle-mediated transport to the plasma membrane cytosol; early endosome; Golgi apparatus; trans-Golgi network GTP binding GTPase activity mRNA binding phospholipase activator activity Arabidopsis thaliana... |
canonical Wnt signaling pathway cellular response to interleukin-4 gamma-delta T cell differentiation immune response regulation of DNA-templated transcription regulation of gamma-delta T cell differentiation regulation of transcription by RNA polymerase II | beta-catenin-TCF complex; nuclear body; nucleoplasm; nucleus | beta-catenin binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding transcription cis-regulatory region binding | Homo sapiens | Activator Alternative promoter usage Alternative splicing DNA-binding Nucleus Reference proteome Repressor Transcription Transcription regulation Wnt signaling pathway | MPQLDSGGGG | MPQLDSGGGGAGGGDDLGAPDELLAFQDEGEEQDDKSRDSAAGPERDLAELKSSLVNESEGAAGGAGIPGVPGAGAGARGEAEALGREHAAQRLFPDKLPEPLEDGLKAPECTSGMYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAPADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPAIVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYE... | canonical Wnt signaling pathway cellular response to interleukin-4 gamma-delta T cell differentiation immune response regulation of DNA-templated transcription regulation of gamma-delta T cell differentiation regulation of transcription by RNA polymerase II beta-catenin-TCF complex; nuclear body; nucleoplasm; nucleus b... |
bicellular tight junction assembly centrosome cycle maintenance of protein location in nucleus negative regulation of GTPase activity positive regulation of cell-substrate adhesion positive regulation of microtubule polymerization protein folding regulation of aerobic respiration regulation of glycolytic process regula... | centrosome; cytoplasm; cytosol; focal adhesion; Golgi apparatus; lateral plasma membrane; microtubule cytoskeleton; mitochondrial intermembrane space; mitochondrial matrix; mitochondrion; nucleolus; nucleoplasm; nucleus | GDP binding GTP binding GTPase activity | Homo sapiens | 3D-structure Alternative splicing Cataract Cell cycle Cytoplasm Cytoskeleton Disease variant GTP-binding Isopeptide bond Lipoprotein Mitochondrion Myristate Nucleotide-binding Nucleus Phosphoprotein Reference proteome Ubl conjugation | MGLLTILKKM | MGLLTILKKMKQKERELRLLMLGLDNAGKTTILKKFNGEDIDTISPTLGFNIKTLEHRGFKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQRMQDCQRELQSLLVEERLAGATLLIFANKQDLPGALSSNAIREVLELDSIRSHHWCIQGCSAVTGENLLPGIDWLLDDISSRIFTAD | bicellular tight junction assembly centrosome cycle maintenance of protein location in nucleus negative regulation of GTPase activity positive regulation of cell-substrate adhesion positive regulation of microtubule polymerization protein folding regulation of aerobic respiration regulation of glycolytic process regula... |
cilium assembly Golgi to plasma membrane transport intraciliary transport kidney development mitotic cytokinesis photoreceptor cell development post-Golgi vesicle-mediated transport protein localization to ciliary membrane protein localization to cilium protein transport small GTPase mediated signal transduction smooth... | centrosome; cilium; cytoplasm; cytoplasmic microtubule; extracellular exosome; Golgi apparatus; Golgi membrane; microtubule cytoskeleton; midbody; nucleoplasm; nucleus; photoreceptor connecting cilium; spindle microtubule | GDP binding GTP binding GTPase activity magnesium ion binding microtubule binding | Homo sapiens | Cell cycle Cell division Cell projection Ciliopathy Cytoplasm Cytoskeleton Direct protein sequencing Disease variant Golgi apparatus GTP-binding Joubert syndrome Lipoprotein Magnesium Membrane Metal-binding Myristate Nucleotide-binding Nucleus Phosphoprotein Protein transport Reference proteome Transport | MGLLSILRKL | MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQGFKLNVWDIGGQRKIRPYWKNYFENTDILIYVIDSADRKRFEETGQELAELLEEEKLSCVPVLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDGMNWVCKNVNAKKK | cilium assembly Golgi to plasma membrane transport intraciliary transport kidney development mitotic cytokinesis photoreceptor cell development post-Golgi vesicle-mediated transport protein localization to ciliary membrane protein localization to cilium protein transport small GTPase mediated signal transduction smooth... |
innate immune response intracellular protein transport positive regulation of autophagy protein ubiquitination vesicle-mediated transport | cytoplasm; Golgi membrane; lysosomal membrane; nucleus; plasma membrane | enzyme activator activity GDP binding GTP binding GTPase activity identical protein binding ubiquitin protein ligase activity ubiquitin-protein transferase activity zinc ion binding | Homo sapiens | 3D-structure Alternative splicing Coiled coil Cytoplasm Golgi apparatus GTP-binding Host-virus interaction Immunity Innate immunity Lysosome Membrane Metal-binding Nucleotide-binding Reference proteome Transferase Ubl conjugation pathway Zinc Zinc-finger | MATLVVNKLG | MATLVVNKLGAGVDSGRQGSRGTAVVKVLECGVCEDVFSLQGDKVPRLLLCGHTVCHDCLTRLPLHGRAIRCPFDRQVTDLGDSGVWGLKKNFALLELLERLQNGPIGQYGAAEESIGISGESIIRCDEDEAHLASVYCTVCATHLCSECSQVTHSTKTLAKHRRVPLADKPHEKTMCSQHQVHAIEFVCLEEGCQTSPLMCCVCKEYGKHQGHKHSVLEPEANQIRASILDMAHCIRTFTEEISDYSRKLVGIVQHIEGGEQIVEDGIGMAHTEHVPGTAENARSCIRAYFYDLHETLCRQEEMALSVVDAHVREKLIW... | innate immune response intracellular protein transport positive regulation of autophagy protein ubiquitination vesicle-mediated transport cytoplasm; Golgi membrane; lysosomal membrane; nucleus; plasma membrane enzyme activator activity GDP binding GTP binding GTPase activity identical protein binding ubiquitin protein ... |
intracellular protein transport positive regulation of autophagy positive regulation of protein modification process protein ubiquitination vesicle-mediated transport | cytoplasm; Golgi membrane; lysosomal membrane; nucleus; plasma membrane | GDP binding GTP binding GTPase activity identical protein binding ubiquitin protein ligase activity ubiquitin-protein transferase activity zinc ion binding | Rattus norvegicus | Alternative splicing Coiled coil Cytoplasm Golgi apparatus GTP-binding Lysosome Membrane Metal-binding Nucleotide-binding Reference proteome Transferase Ubl conjugation pathway Zinc Zinc-finger | MAALAVNKPG | MAALAVNKPGAGVDSGRQGSRGTAVVKVLECGVCEDVFSLQGDKVPRLLLCGHTVCHDCLTRLPLHGRAIRCPFDRQVTDLGDSGVWGLKKNFALLELLERLQNGHIGQYGAAEEALGISGESIIRCDEDEAHVASVYCTVCATHLCSECSQVTHSTKTLAKHRRVPLADKPHEKTMCCQHQVHAIEFVCLEEACQTSPLMCCVCKEYGKHQGHKHSVLEPEANQIRASILDMAHCIRTFTEEISDYSRKLVGIVQHIEGGEQIVEDGIGMAHTEHVPGTAENARSCVRAYFSDLHETLCRQEEMALSVVDAHVREKLIW... | intracellular protein transport positive regulation of autophagy positive regulation of protein modification process protein ubiquitination vesicle-mediated transport cytoplasm; Golgi membrane; lysosomal membrane; nucleus; plasma membrane GDP binding GTP binding GTPase activity identical protein binding ubiquitin prote... |
adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway aggregation involved in sorocarp development chemotaxis to cAMP chemotaxis to folate cortical actin cytoskeleton organization G protein-coupled chemorepellent receptor... | cytoplasm; cytosol; heterotrimeric G-protein complex; phagocytic vesicle; plasma membrane; vesicle | enzyme activator activity G-protein alpha-subunit binding G-protein gamma-subunit binding protein kinase regulator activity signaling receptor complex adaptor activity | Dictyostelium discoideum | Cell membrane Chemotaxis Cytoplasm Membrane Reference proteome Repeat Sensory transduction Transducer WD repeat | MSSDISEKIQ | MSSDISEKIQQARRDAESMKEQIRANRDVMNDTTLKTFTRDLPGLPKMEGKIKVRRNLKGHLAKIYAMHWAEDNVHLVSASQDGKLLVWDGLTTNKVHAIPLRSSWVMTCAYSPTANFVACGGLDNICSIYNLRSREQPIRVCRELNSHTGYLSCCRFLNDRQIVTSSGDMTCILWDVENGTKITEFSDHNGDVMSVSVSPDKNYFISGACDATAKLWDLRSGKCVQTFTGHEADINAVQYFPNGLSFGTGSDDASCRLFDIRADRELMQYTHDNILCGITSVGFSFSGRFLFAGYDDFTCNVWDTLKGERVLSLTGHGN... | adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway aggregation involved in sorocarp development chemotaxis to cAMP chemotaxis to folate cortical actin cytoskeleton organization G protein-coupled chemorepellent receptor... |
autophagic cell death Golgi organization hypotonic response phagocytosis regulation of response to osmotic stress regulation of vesicle-mediated transport sorocarp development vesicle-mediated transport | contractile vacuolar membrane; Golgi apparatus; Golgi membrane; lipid droplet; pathogen-containing vacuole; plasma membrane | GTP binding GTPase activity | Dictyostelium discoideum | Cell membrane GTP-binding Hydrolase Lipoprotein Membrane Nucleotide-binding Prenylation Reference proteome | MYSFLFKYII | MYSFLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDNKAIKLQIWDTAGQESFRSITRSYYRGSAGALLVYDITRRDTFNHLTCWLKDARSYANSNMTIILIGNKSDMESKRAVSYEEGRQFADENGLIFLETSAKTASNVEEAFVNTASKIYEKIQKGDFDINNESFGIKLGAPTSKQDGTDQKPAGGGCCK | autophagic cell death Golgi organization hypotonic response phagocytosis regulation of response to osmotic stress regulation of vesicle-mediated transport sorocarp development vesicle-mediated transport contractile vacuolar membrane; Golgi apparatus; Golgi membrane; lipid droplet; pathogen-containing vacuole; plasma me... |
contractile vacuole organization defense response to bacterium endocytic recycling Golgi to endosome transport hypotonic response intracellular protein transport phagolysosome assembly involved in apoptotic cell clearance regulation of endosomal vesicle fusion regulation of pinocytosis response to osmotic stress | contractile vacuolar membrane; cytosol; early endosome; endomembrane system; lipid droplet; lysosomal membrane; lysosome; pathogen-containing vacuole; phagocytic vesicle; recycling endosome; spongiome; trans-Golgi network | GTP binding GTPase activity | Dictyostelium discoideum | Endosome GTP-binding Lipoprotein Membrane Methylation Nucleotide-binding Prenylation Reference proteome Vacuole | MSFPYEYIFK | MSFPYEYIFKYIIIGDMGVGKSCLLHQFTENKFVPDSPHTIGVEFGTRIVDVNNKKIKLQIWDTAGQERFRAVTRSYYRGAAGALLVYDITRRITYNHLTTWLTDARNLTNPNTVIMLIGNKKDLEGQRDVTYEEASAFAKQNGLIFVESSAKTGENVEEAFLRTAKLIFQSVQEGNVDLIPDGGITKNPPQTITDKPQDASKCSC | contractile vacuole organization defense response to bacterium endocytic recycling Golgi to endosome transport hypotonic response intracellular protein transport phagolysosome assembly involved in apoptotic cell clearance regulation of endosomal vesicle fusion regulation of pinocytosis response to osmotic stress contra... |
endosome to plasma membrane protein transport hypotonic response lipid catabolic process lipophagy phagocytosis phagosome-lysosome fusion positive regulation of macropinocytosis regulation of phagosome maturation regulation of vesicle-mediated transport | autophagosome membrane; cytosol; early phagosome; early phagosome membrane; endocytic vesicle; late endosome; late endosome membrane; lipid droplet; lysosomal membrane; lysosome; macropinosome; pathogen-containing vacuole; phagocytic vesicle; plasma membrane; post-lysosomal vacuole | G protein activity GTP binding | Dictyostelium discoideum | Autophagy Cytoplasmic vesicle Endosome GTP-binding Hydrolase Lipid degradation Lipid droplet Lipid metabolism Lipoprotein Lysosome Membrane Nucleotide-binding Prenylation Reference proteome | MATKKKVLLK | MATKKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKELMVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLCYDVNVAKTFENLDSWRDEFLIQAGPRDPDNFPFVVLGNKIDLENQRVVSQKRAASWCQSKGNIPYFETSAKEAINVEQAFQTIARNAIKLEDGLVFPIPTNIQVIPEPQPAKSGCC | endosome to plasma membrane protein transport hypotonic response lipid catabolic process lipophagy phagocytosis phagosome-lysosome fusion positive regulation of macropinocytosis regulation of phagosome maturation regulation of vesicle-mediated transport autophagosome membrane; cytosol; early phagosome; early phagosome ... |
cellular hypotonic response contractile vacuole organization exocytosis osmosensory signaling pathway protein localization to vacuolar membrane protein transport Rab protein signal transduction small GTPase mediated signal transduction | contractile vacuolar membrane; contractile vacuole; Golgi apparatus; lipid droplet; pathogen-containing vacuole; phagocytic vesicle; recycling endosome | GTP binding GTPase activating protein binding GTPase activity nucleotide binding | Dictyostelium discoideum | GTP-binding Lipoprotein Membrane Nucleotide-binding Prenylation Protein transport Reference proteome Transport Vacuole | MTSKGSQEEY | MTSKGSQEEYDYLYKIVLIGDSGVGKSNLLSRFTRNEFSLETKSTIGVEFATRTIQTEGKTIKAQVWDTAGQERYRAITSAYYRGAVGALLVYDIAKQATYKSVERWILELRENADRNIEIMLVGNKSDLRHLREVSTDEAKEFSEKHKLTFIETSALDSSNVELAFQNILTQIYHIMSRPSHSTGPQTTIDSNTETIILPTTSEPPAAKSGCC | cellular hypotonic response contractile vacuole organization exocytosis osmosensory signaling pathway protein localization to vacuolar membrane protein transport Rab protein signal transduction small GTPase mediated signal transduction contractile vacuolar membrane; contractile vacuole; Golgi apparatus; lipid droplet; ... |
adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway autophagic cell death positive regulation of aggregation involved in sorocarp development regulation of transcription by RNA polymerase II response to catechin sorocarp development | cytosol; nucleus | DNA binding DNA-binding transcription factor activity sequence-specific DNA binding | Dictyostelium discoideum | Activator Direct protein sequencing DNA-binding Nucleus Reference proteome Repeat Transcription Transcription regulation | MLSTHHHQGN | MLSTHHHQGNSSSSSSSSSPSQTIGGSDLSNISALPLPLPSIFTTAQNQMNPPILFPPTSSLLGGSSNTPSFLLPPSSIMSSNVFPSHDGQYPDMPNMVDQYQIHPNQNPHYNYQYQLMFMQQQAQQNQPPQQNQQQQHHQQQQQQPQHHQQMQQQQHHQQMQQQQQHHQQMQQQQHHQQMQHHQLQQHQHQHQQQQQQQQHQQQHHQQQQQQQQQHHQQQQHHQHSQPQQQHQHNQQQQHQHNQQQHQQQQNQIQMVPQQPQSLSNSGNNNNNNNNNNNSNNNNNNNNNNNSHQLNNLTLSQNNTSGSNTPSPSTKGKR... | adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway autophagic cell death positive regulation of aggregation involved in sorocarp development regulation of transcription by RNA polymerase II response to catechin sorocarp development cytosol; nucleus DNA binding DNA-binding transcription facto... |
tyrosyl-tRNA aminoacylation | cytoplasm; cytoplasmic stress granule; nucleus | ATP binding mRNA binding tyrosine-tRNA ligase activity | Saccharomyces cerevisiae | 3D-structure Acetylation Aminoacyl-tRNA synthetase ATP-binding Cytoplasm Direct protein sequencing Ligase Nucleotide-binding Nucleus Phosphoprotein Protein biosynthesis Reference proteome | MSSAATVDPN | MSSAATVDPNEAFGLITKNLQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGRPHCGYFVPMTKLADFLKAGCEVTVLLADLHAFLDNMKAPLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGADVVKQVANPLLSGLIYPLMQALDEQFLDVDCQFGGVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGGKMSASDPNSKIDLLEEPKQVKKKINSAFCSPGNVEENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFEEMKLAFKEEKLSPP... | tyrosyl-tRNA aminoacylation cytoplasm; cytoplasmic stress granule; nucleus ATP binding mRNA binding tyrosine-tRNA ligase activity Saccharomyces cerevisiae 3D-structure Acetylation Aminoacyl-tRNA synthetase ATP-binding Cytoplasm Direct protein sequencing Ligase Nucleotide-binding Nucleus Phosphoprotein Protein biosynth... |
icosanoid metabolic process intracellular chloride ion homeostasis positive regulation of vasoconstriction prostaglandin biosynthetic process response to ethanol response to fatty acid | cytosol; endoplasmic reticulum; endoplasmic reticulum membrane | 12-hydroxyheptadecatrienoic acid synthase activity heme binding hydroperoxy icosatetraenoate dehydratase activity iron ion binding monooxygenase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen thromboxane-A synthase activity | Mus musculus | Endoplasmic reticulum Fatty acid biosynthesis Fatty acid metabolism Heme Iron Isomerase Lipid biosynthesis Lipid metabolism Lyase Membrane Metal-binding Monooxygenase Oxidoreductase Prostaglandin biosynthesis Prostaglandin metabolism Reference proteome Transmembrane Transmembrane helix | MEVLGLLKFE | MEVLGLLKFEVSGTIVTVTLLVALLALLKWYSMSAFSRLEKLGIRHPKPSPFVGNLMFFRQGFWESQLELRERYGPLCGYYLGRRMHVVISEPDMIKQVLVENFSNFSNRMASGLEPKMVADSVLLLRDRRWEEVRGALMSSFSPEKLDEMTPLISQACELLVAHLKRYAASRDAFNIQRCYCCYTIDVVASVAFGTQVDSQNSPEDPFVQHCRRASTFCIPRPLLVLILSFPSIMVPLARILPNKNRDELNGFFNTLIRNVIALRDQQAAEERRRDFLQMVLDAQHSMNSVGVEGFDMVPESLSSSECTKEPPQRCHPT... | icosanoid metabolic process intracellular chloride ion homeostasis positive regulation of vasoconstriction prostaglandin biosynthetic process response to ethanol response to fatty acid cytosol; endoplasmic reticulum; endoplasmic reticulum membrane 12-hydroxyheptadecatrienoic acid synthase activity heme binding hydroper... |
mitochondrial alanyl-tRNA aminoacylation | chloroplast; mitochondrion; nucleus | alanine-tRNA ligase activity ATP binding tRNA binding zinc ion binding | Arabidopsis thaliana | Alternative initiation Aminoacyl-tRNA synthetase ATP-binding Cytoplasm Ligase Metal-binding Mitochondrion Nucleotide-binding Phosphoprotein Protein biosynthesis Reference proteome RNA-binding Transit peptide tRNA-binding Zinc | MRLVKAASLL | MRLVKAASLLISSTKPPSRVFYSSHLRRPFFSHFRFSSSSSTSSSVAVMPGSEPSETQWPAKRVRDTYVDFFRGKGHKFWPSSPVVPHNDPTLLFANAGMNQYKPIFLGTADPNTELSKLSRACNTQKCIRAGGKHNDLDDVGKDTYHHTFFEMLGNWSFGDYFKKEAIEWAWELLTKVYGLPTDRIYATYFGGDEKAGLQPDNEARDIWLKVLPSGRVLPFGCKDNFWEMGDTGPCGPCTEIHYDRIGNRDAASLVNNDDPTCLEIWNLVFIQFNRESDGSLKPLPAKHVDTGMGFERLTSVLQNKMSNYDTDVFMPIF... | mitochondrial alanyl-tRNA aminoacylation chloroplast; mitochondrion; nucleus alanine-tRNA ligase activity ATP binding tRNA binding zinc ion binding Arabidopsis thaliana Alternative initiation Aminoacyl-tRNA synthetase ATP-binding Cytoplasm Ligase Metal-binding Mitochondrion Nucleotide-binding Phosphoprotein Protein bio... |
defense response to bacterium killing of cells of another organism | extracellular region | signaling receptor binding | Lactococcus lactis subsp. lactis | Antibiotic Antimicrobial Bacteriocin Direct protein sequencing Lantibiotic Thioether bond | MKEQNSFNLL | MKEQNSFNLLQEVTESELDLILGAKGGSGVIHTISHECNMNSWQFVFTCCS | defense response to bacterium killing of cells of another organism extracellular region signaling receptor binding Lactococcus lactis subsp. lactis Antibiotic Antimicrobial Bacteriocin Direct protein sequencing Lantibiotic Thioether bond MKEQNSFNLL MKEQNSFNLLQEVTESELDLILGAKGGSGVIHTISHECNMNSWQFVFTCCS |
epithelial cell proliferation involved in lung morphogenesis ERBB2-ERBB3 signaling pathway ERK1 and ERK2 cascade face development heart development insulin-like growth factor receptor signaling pathway lung morphogenesis MAPK cascade myelination negative regulation of gene expression phosphorylation positive regulation... | cell cortex; cell-cell junction; cytoplasm; cytoplasmic side of plasma membrane; cytosol; early endosome; endoplasmic reticulum; focal adhesion; Golgi apparatus; late endosome; microtubule; mitochondrion; nucleus; perinuclear region of cytoplasm | ATP binding MAP kinase kinase activity MAP-kinase scaffold activity metal ion binding molecular adaptor activity PDZ domain binding protein serine kinase activity protein serine/threonine kinase activator activity protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosin... | Rattus norvegicus | Acetylation ATP-binding Cytoplasm Kinase Magnesium Membrane Metal-binding Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase Tyrosine-protein kinase | MLARRKPVLP | MLARRKPVLPALTINPTIAEGPSPTSEGASEAHLVDLQKKLEELDLDEQQRKRLEAFLTQKAKVGELKDDDFERISELGAGNGGVVTKARHRPSGLIMARKLIHLEIKPAVRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEDILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVELAIGRYPIPPPDAKELEASFGRPVVDGADGEPHSVSPRPRPPGRPISGHGMDSRPAMAIFE... | epithelial cell proliferation involved in lung morphogenesis ERBB2-ERBB3 signaling pathway ERK1 and ERK2 cascade face development heart development insulin-like growth factor receptor signaling pathway lung morphogenesis MAPK cascade myelination negative regulation of gene expression phosphorylation positive regulation... |
epithelial cell proliferation involved in lung morphogenesis ERBB2-ERBB3 signaling pathway ERK1 and ERK2 cascade face development heart development insulin-like growth factor receptor signaling pathway MAPK cascade myelination peptidyl-serine autophosphorylation positive regulation of axonogenesis positive regulation o... | cell-cell junction; cytoplasmic side of plasma membrane; cytosol; early endosome; endoplasmic reticulum; extracellular region; focal adhesion; Golgi apparatus; late endosome; microtubule; mitochondrion; nucleus; perinuclear region of cytoplasm; peroxisomal membrane | ATP binding MAP kinase kinase activity MAP-kinase scaffold activity metal ion binding PDZ domain binding protein serine kinase activity protein serine/threonine kinase activator activity protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity scaffold ... | Homo sapiens | 3D-structure Acetylation ATP-binding Cardiomyopathy Cytoplasm Direct protein sequencing Disease variant Ectodermal dysplasia Intellectual disability Kinase Magnesium Membrane Metal-binding Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase Tyrosine-protein kinase | MLARRKPVLP | MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQKAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQGTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRPPGRPVSGHGMDSRPAMAIFE... | epithelial cell proliferation involved in lung morphogenesis ERBB2-ERBB3 signaling pathway ERK1 and ERK2 cascade face development heart development insulin-like growth factor receptor signaling pathway MAPK cascade myelination peptidyl-serine autophosphorylation positive regulation of axonogenesis positive regulation o... |
central nervous system development positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase III | nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA binding | Homo sapiens | Alternative splicing DNA-binding Isopeptide bond Metal-binding Nucleus Reference proteome Repeat Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | MESLGLHTVT | MESLGLHTVTLSDGTTAYVQQAVKGEKLLEGQVIQLEDGTTAYIHQVTVQKEALSFEDGQPVQLEDGSMAYIHRTPREGYDPSTLEAVQLEDGSTAYIHHPVAVPSESTILAVQTEVGLEDLAAEDDEGFSADAVVALEQYASKVLHDSQIPRNGKGQQVGDRAFRCGYKGCGRLYTTAHHLKVHERAHTGDRPYRCDFPSCGKAFATGYGLKSHVRTHTGEKPYKCPEELCSKAFKTSGDLQKHVRTHTGERPFQCPFEGCGRSFTTSNIRKVHVRTHTGERPYTCPEPHCGRGFTSATNYKNHVRIHTGEKPYVCTVP... | central nervous system development positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase III nucleus DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA ... |
bile acid metabolic process cellular glucuronidation response to toxic substance sensory perception of chemical stimulus sensory perception of smell | membrane | glucuronosyltransferase activity | Rattus norvegicus | Glycoprotein Glycosyltransferase Lipid metabolism Membrane Olfaction Reference proteome Sensory transduction Signal Transferase Transmembrane Transmembrane helix | MLKNILLWSL | MLKNILLWSLQLSLLGMSLGGNVLIWPMEGSHWLNVKIIIDELLRKEHNVTVLVASGALFITPSVSPSLTFEIYPVPFGKEKIESVIKDFVLTWLENRPSPSTIWTFYKEMAKVIEEFHLVSRGICDGVLKNEKLMTKLQRGKFEVLLSDPVFPCGDIVALKLGIPFIYSLRFSPASTVEKHCGKVPFPPSYVPAILSELTDQMSFADRVRNFISYRMQDYMFETLWKQWDSYYSKALGRPTTLCETMGKAEIWLMRTYWDFEFPRPYLPNFEFVGGLHCKPAKPLPKEMEEFVQTSGEHGVVVFSLGSMVKNLTEEKAN... | bile acid metabolic process cellular glucuronidation response to toxic substance sensory perception of chemical stimulus sensory perception of smell membrane glucuronosyltransferase activity Rattus norvegicus Glycoprotein Glycosyltransferase Lipid metabolism Membrane Olfaction Reference proteome Sensory transduction Si... |
aromatic compound catabolic process cellular glucuronidation estrogen metabolic process response to xenobiotic stimulus | endoplasmic reticulum membrane | glucuronosyltransferase activity | Rattus norvegicus | Direct protein sequencing Endoplasmic reticulum Glycoprotein Glycosyltransferase Lipid metabolism Membrane Reference proteome Signal Steroid metabolism Transferase Transmembrane Transmembrane helix | MSGKWISALL | MSGKWISALLLLQISFCFKSGNCGKVLVWPMEYSHWMNIKIILEELVQKGHEVTVLRPSAFVFLDPKETSDLKFVTFPTSFSSHDLENFFTRFVNVWTYELPRDTCLSYFLYLQDTIDEYSDYCLTVCKEAVSNKQFMTKLQESKFDVVFSDAIGPCGELIAELLQIPFLYSLRFSPGYTIEQYIGGVLFPPSYVPMIFSGLAGQMTFIERVHNMICMLYFDFWFQTFREKKWDPFYSKTLGRPTTLAEIMGKAEMWLIRSYWDLEFPHPISPNVDYIGGLHCKPAKPLPKDIEDFVQSSGEHGVVVFSLGSMVRNMTEE... | aromatic compound catabolic process cellular glucuronidation estrogen metabolic process response to xenobiotic stimulus endoplasmic reticulum membrane glucuronosyltransferase activity Rattus norvegicus Direct protein sequencing Endoplasmic reticulum Glycoprotein Glycosyltransferase Lipid metabolism Membrane Reference p... |
mitochondrial translation | mitochondrial inner membrane; mitochondrial large ribosomal subunit; mitochondrion | structural constituent of ribosome | Saccharomyces cerevisiae | 3D-structure Direct protein sequencing Mitochondrion Reference proteome Ribonucleoprotein Ribosomal protein Transit peptide | MLKSIFAKRF | MLKSIFAKRFASTGSYPGSTRITLPRRPAKKIQLGKSRPAIYHQFNVKMELSDGSVVIRRSQYPKGEIRLIQDQRNNPLWNPSRDDLVVVDANSGGSLDRFNKRYSSLFSVDSTTPNSSSETVELSEENKKKTQIKKEEKEDVSEKAFGMDDYLSLLDDSEQQIKSGKLASKKRDKK | mitochondrial translation mitochondrial inner membrane; mitochondrial large ribosomal subunit; mitochondrion structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Direct protein sequencing Mitochondrion Reference proteome Ribonucleoprotein Ribosomal protein Transit peptide MLKSIFAKRF MLKSIFAKRFASTGS... |
COPII-coated vesicle cargo loading endoplasmic reticulum to Golgi vesicle-mediated transport intracellular protein transport membrane organization negative regulation of cargo loading into COPII-coated vesicle positive regulation of protein exit from endoplasmic reticulum regulation of cargo loading into COPII-coated v... | COPII vesicle coat; endoplasmic reticulum; endoplasmic reticulum exit site; Golgi apparatus; sarcoplasmic reticulum | GTP binding GTPase activity | Mus musculus | Endoplasmic reticulum ER-Golgi transport Golgi apparatus GTP-binding Nucleotide-binding Phosphoprotein Protein transport Reference proteome Transport | MSFIFEWIYN | MSFIFEWIYNGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLQMLKDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHEQARRVWKNYLPAINGIVFLVDCADHSRLMESKVELNALMTDETISNVPILILGNKIDRTDAISEEKLREIKGLYGQTTGKGNVTLKELNARPMEVFMCSVLKRQGYGEGFRWLSQYID | COPII-coated vesicle cargo loading endoplasmic reticulum to Golgi vesicle-mediated transport intracellular protein transport membrane organization negative regulation of cargo loading into COPII-coated vesicle positive regulation of protein exit from endoplasmic reticulum regulation of cargo loading into COPII-coated v... |
ATP biosynthetic process oxidative phosphorylation proton motive force-driven ATP synthesis proton motive force-driven mitochondrial ATP synthesis | membrane; mitochondrial inner membrane; mitochondrial matrix; mitochondrial proton-transporting ATP synthase complex; mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1); mitochondrion | proton-transporting ATP synthase activity, rotational mechanism RNA binding | Homo sapiens | 3D-structure Acetylation Alternative splicing ATP synthesis CF(1) Direct protein sequencing Hydrogen ion transport Ion transport Membrane Mitochondrion Mitochondrion inner membrane Phosphoprotein Reference proteome Transit peptide Transport | MFSRAGVAGL | MFSRAGVAGLSAWTLQPQWIQVRNMATLKDITRRLKSIKNIQKITKSMKMVAAAKYARAERELKPARIYGLGSLALYEKADIKGPEDKKKHLLIGVSSDRGLCGAIHSSIAKQMKSEVATLTAAGKEVMLVGIGDKIRGILYRTHSDQFLVAFKEVGRKPPTFGDASVIALELLNSGYEFDEGSIIFNKFRSVISYKTEEKPIFSLNTVASADSMSIYDDIDADVLQNYQEYNLANIIYYSLKESTTSEQSARMTAMDNASKNASEMIDKLTLTFNRTRQAVITKELIEIISGAAALD | ATP biosynthetic process oxidative phosphorylation proton motive force-driven ATP synthesis proton motive force-driven mitochondrial ATP synthesis membrane; mitochondrial inner membrane; mitochondrial matrix; mitochondrial proton-transporting ATP synthase complex; mitochondrial proton-transporting ATP synthase complex,... |
proton transmembrane transport regulation of macroautophagy synaptic vesicle lumen acidification | apical plasma membrane; clathrin-coated vesicle membrane; cytosol; endosome; extracellular exosome; lysosomal membrane; microvillus; proton-transporting two-sector ATPase complex; synaptic vesicle membrane; vacuolar proton-transporting V-type ATPase, V1 domain | ATPase binding proton-transporting ATPase activity, rotational mechanism | Homo sapiens | 3D-structure Acetylation Alternative splicing Cell membrane Cytoplasmic vesicle Direct protein sequencing Disease variant Hydrogen ion transport Ion transport Membrane Phosphoprotein Reference proteome Synapse Transport | MALSDADVQK | MALSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKKEKQIEQQKKIQMSNLMNQARLKVLRARDDLITDLLNEAKQRLSKVVKDTTRYQVLLDGLVLQGLYQLLEPRMIVRCRKQDFPLVKAAVQKAIPMYKIATKNDVDVQIDQESYLPEDIAGGVEIYNGDRKIKVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD | proton transmembrane transport regulation of macroautophagy synaptic vesicle lumen acidification apical plasma membrane; clathrin-coated vesicle membrane; cytosol; endosome; extracellular exosome; lysosomal membrane; microvillus; proton-transporting two-sector ATPase complex; synaptic vesicle membrane; vacuolar proton-... |
cell wall organization peptidoglycan catabolic process | outer membrane-bounded periplasmic space; periplasmic space | N-acetylmuramoyl-L-alanine amidase activity zinc ion binding | Escherichia coli | 3D-structure Cell wall biogenesis/degradation Hydrolase Periplasm Reference proteome Signal | MSTFKPLKTL | MSTFKPLKTLTSRRQVLKAGLAALTLSGMSQAIAKDELLKTSNGHSKPKAKKSGGKRVVVLDPGHGGIDTGAIGRNGSKEKHVVLAIAKNVRSILRNHGIDARLTRSGDTFIPLYDRVEIAHKHGADLFMSIHADGFTNPKAAGASVFALSNRGASSAMAKYLSERENRADEVAGKKATDKDHLLQQVLFDLVQTDTIKNSLTLGSHILKKIKPVHKLHSRNTEQAAFVVLKSPSVPSVLVETSFITNPEEERLLGTAAFRQKIATAIAEGVISYFHWFDNQKAHSKKR | cell wall organization peptidoglycan catabolic process outer membrane-bounded periplasmic space; periplasmic space N-acetylmuramoyl-L-alanine amidase activity zinc ion binding Escherichia coli 3D-structure Cell wall biogenesis/degradation Hydrolase Periplasm Reference proteome Signal MSTFKPLKTL MSTFKPLKTLTSRRQVLKAGLAAL... |
heme A biosynthetic process heme B biosynthetic process heme biosynthetic process heme O biosynthetic process protoporphyrinogen IX biosynthetic process | cytoplasm; cytosol; membrane; mitochondrial intermembrane space; mitochondrion | coproporphyrinogen oxidase activity protein homodimerization activity structural constituent of eye lens | Homo sapiens | 3D-structure Acetylation Alternative splicing Disease variant Heme biosynthesis Hereditary hemolytic anemia Mitochondrion Oxidoreductase Phosphoprotein Porphyrin biosynthesis Reference proteome Transit peptide | MALQLGRLSS | MALQLGRLSSGPCWLVARGGCGGPRAWSQCGGGGLRAWSQRSAAGRVCRPPGPAGTEQSRGLGHGSTSRGGPWVGTGLAAALAGLVGLATAAFGHVQRAEMLPKTSGTRATSLGRPEEEEDELAHRCSSFMAPPVTDLGELRRRPGDMKTKMELLILETQAQVCQALAQVDGGANFSVDRWERKEGGGGISCVLQDGCVFEKAGVSISVVHGNLSEEAAKQMRSRGKVLKTKDGKLPFCAMGVSSVIHPKNPHAPTIHFNYRYFEVEEADGNKQWWFGGGCDLTPTYLNQEDAVHFHRTLKEACDQHGPDLYPKFKKWCD... | heme A biosynthetic process heme B biosynthetic process heme biosynthetic process heme O biosynthetic process protoporphyrinogen IX biosynthetic process cytoplasm; cytosol; membrane; mitochondrial intermembrane space; mitochondrion coproporphyrinogen oxidase activity protein homodimerization activity structural constit... |
heme A biosynthetic process heme B biosynthetic process heme biosynthetic process heme O biosynthetic process potassium ion transport protoporphyrinogen IX biosynthetic process sodium ion transport | cytoplasm; cytosol; membrane; mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrion | coproporphyrinogen oxidase activity identical protein binding P-type sodium:potassium-exchanging transporter activity protein homodimerization activity structural constituent of eye lens | Mus musculus | Acetylation Direct protein sequencing Heme biosynthesis Mitochondrion Oxidoreductase Phosphoprotein Porphyrin biosynthesis Reference proteome Transit peptide | MALRLGRLGS | MALRLGRLGSDPWWRAVLGDYAQLRAASPRCASARVCQLPGTAGPQPRRGLGYGPWARGGSGLGTRLAATLAGLAGLAAAAFGHVQRAEMVPKSSGARSPSPGRREEDGDELARRCSTFMSSPVTELRELRRRPEDMKTKMELMIMETQAQVCRALAQVDGVADFTVDRWERKEGGGGITCVLQDGRVFEKAGVSISVVHGNLSEEAANQMRGRGKTLKTKDSKLPFTAMGVSSVIHPKNPYAPTMHFNYRYFEVEEADGNTHWWFGGGCDLTPTYLNQEDAVHFHRTLKEACDQHGPDIYPKFKKWCDDYFFIVHRGER... | heme A biosynthetic process heme B biosynthetic process heme biosynthetic process heme O biosynthetic process potassium ion transport protoporphyrinogen IX biosynthetic process sodium ion transport cytoplasm; cytosol; membrane; mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrion coproporphyri... |
heme biosynthetic process protoporphyrinogen IX biosynthetic process response to hydroperoxide | cytoplasm | coproporphyrinogen oxidase activity manganese ion binding protein homodimerization activity tetrapyrrole binding | Escherichia coli | Cytoplasm Direct protein sequencing Heme biosynthesis Manganese Metal-binding Oxidoreductase Porphyrin biosynthesis Reference proteome | MKPDAHQVKQ | MKPDAHQVKQFLLNLQDTICQQLTAVDGAEFVEDSWQREAGGGGRSRVLRNGGVFEQAGVNFSHVHGEAMPASATAHRPELAGRSFEAMGVSLVVHPHNPYVPTSHANVRFFIAEKPGADPVWWFGGGFDLTPFYGFEEDAIHWHRTARDLCLPFGEDVYPRYKKWCDEYFYLKHRNEQRGIGGLFFDDLNTPDFDRCFAFMQAVGKGYTDAYLPIVERRKAMAYGERERNFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEYDYQPKDGSPEAALSEFIKVRDWV | heme biosynthetic process protoporphyrinogen IX biosynthetic process response to hydroperoxide cytoplasm coproporphyrinogen oxidase activity manganese ion binding protein homodimerization activity tetrapyrrole binding Escherichia coli Cytoplasm Direct protein sequencing Heme biosynthesis Manganese Metal-binding Oxidore... |
G protein-coupled receptor internalization regulation of protein phosphorylation signal transduction visual perception | cytoplasm; photoreceptor inner segment; photoreceptor outer segment; synapse | G protein-coupled receptor binding opsin binding phosphoprotein binding | Homo sapiens | Alternative splicing Cell projection Disease variant Disulfide bond Reference proteome Sensory transduction Vision | MSKVFKKTSS | MSKVFKKTSSNGKLSIYLGKRDFVDHVDTVEPIDGVVLVDPEYLKCRKLFVMLTCAFRYGRDDLEVIGLTFRKDLYVQTLQVVPAESSSPQGPLTVLQERLLHKLGDNAYPFTLQMVTNLPCSVTLQPGPEDAGKPCGIDFEVKSFCAENPEETVSKRDYVRLVVRKVQFAPPEAGPGPSAQTIRRFLLSAQPLQLQAWMDREVHYHGEPISVNVSINNCTNKVIKKIKISVDQITDVVLYSLDKYTKTVFIQEFTETVAANSSFSQSFAVTPILAASCQKRGLALDGKLKHEDTNLASSTIIRPGMDKELLGILVSYKV... | G protein-coupled receptor internalization regulation of protein phosphorylation signal transduction visual perception cytoplasm; photoreceptor inner segment; photoreceptor outer segment; synapse G protein-coupled receptor binding opsin binding phosphoprotein binding Homo sapiens Alternative splicing Cell projection Di... |
cytoplasmic translation translation | cytoplasm; cytosol; cytosolic large ribosomal subunit; cytosolic ribosome; extracellular exosome; focal adhesion; membrane; nucleolus; nucleus; ribonucleoprotein complex; rough endoplasmic reticulum | RNA binding structural constituent of ribosome | Homo sapiens | 3D-structure Acetylation Citrullination Cytoplasm Direct protein sequencing Isopeptide bond Methylation Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation | MACARPLISV | MACARPLISVYSEKGESSGKNVTLPAVFKAPIRPDIVNFVHTNLRKNNRQPYAVSELAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRRVNTTQKRYAICSALAASALPALVMSKGHRIEEVPELPLVVEDKVEGYKKTKEAVLLLKKLKAWNDIKKVYASQRMRAGKGKMRNRRRIQRRGPCIIYNEDNGIIKAFRNIPGITLLNVSKLNILKLAPGGHVGRFCIWTESAFRKLDELYGTWRKAASLKSNYNLPMHKMINTDLSRILKSPEIQRALRAPRKKIHRRVLKKNPLK... | cytoplasmic translation translation cytoplasm; cytosol; cytosolic large ribosomal subunit; cytosolic ribosome; extracellular exosome; focal adhesion; membrane; nucleolus; nucleus; ribonucleoprotein complex; rough endoplasmic reticulum RNA binding structural constituent of ribosome Homo sapiens 3D-structure Acetylation ... |
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