Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
|---|---|---|---|---|---|---|---|
regulation of cytokine production T cell mediated immunity T cell receptor signaling pathway | external side of plasma membrane; membrane; plasma membrane | signaling receptor binding | Homo sapiens | 3D-structure Adaptive immunity Alternative splicing Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Immunity Immunoglobulin domain Membrane Reference proteome Repeat Signal Transmembrane Transmembrane helix | MKMASSLAFL | MKMASSLAFLLLNFHVSLFLVQLLTPCSAQFSVLGPSGPILAMVGEDADLPCHLFPTMSAETMELRWVSSSLRQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNVTASDSGKYLCYFQDGDFYEKALVELKVAALGSDLHIEVKGYEDGGIHLECRSTGWYPQPQIKWSDTKGENIPAVEAPVVADGVGLYAVAASVIMRGSSGGGVSCIIRNSLLGLEKTASISIADPFFRSAQPWIAALAGTLPISLLLLAGASYFLWRQQKEKIALSRETEREREMKEMGYAATEQEISLREKLQEELKWRKIQYM... | regulation of cytokine production T cell mediated immunity T cell receptor signaling pathway external side of plasma membrane; membrane; plasma membrane signaling receptor binding Homo sapiens 3D-structure Adaptive immunity Alternative splicing Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Immunit... |
activated T cell proliferation adaptive immune response positive regulation of cytokine production positive regulation of type II interferon production regulation of cytokine production T cell receptor signaling pathway | external side of plasma membrane; plasma membrane | signaling receptor binding | Homo sapiens | 3D-structure Adaptive immunity Alternative splicing Cell membrane Disulfide bond Glycoprotein Immunity Immunoglobulin domain Membrane Reference proteome Repeat Signal Transmembrane Transmembrane helix | MKMASFLAFL | MKMASFLAFLLLNFRVCLLLLQLLMPHSAQFSVLGPSGPILAMVGEDADLPCHLFPTMSAETMELKWVSSSLRQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNVTASDSGKYLCYFQDGDFYEKALVELKVAALGSDLHVDVKGYKDGGIHLECRSTGWYPQPQIQWSNNKGENIPTVEAPVVADGVGLYAVAASVIMRGSSGEGVSCTIRSSLLGLEKTASISIADPFFRSAQRWIAALAGTLPVLLLLLGGAGYFLWQQQEEKKTQFRKKKREQELREMAWSTMKQEQSTRVKLLEELRWRSIQYA... | activated T cell proliferation adaptive immune response positive regulation of cytokine production positive regulation of type II interferon production regulation of cytokine production T cell receptor signaling pathway external side of plasma membrane; plasma membrane signaling receptor binding Homo sapiens 3D-structu... |
acinar cell differentiation bile acid metabolic process calcineurin-mediated signaling cellular response to leukemia inhibitory factor cholesterol homeostasis embryo development ending in birth or egg hatching homeostatic process hormone-mediated signaling pathway pancreas morphogenesis positive regulation of DNA-templ... | chromatin; cytoplasm; nucleoplasm; nucleus; RNA polymerase II transcription regulator complex | chromatin binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific nuclear receptor activity phospholipid binding RNA polymerase II cis-regulatory region sequence-specific ... | Homo sapiens | 3D-structure Activator Alternative splicing DNA-binding Isopeptide bond Lipid-binding Metal-binding Nucleus Receptor Reference proteome Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | MSSNSDTGDL | MSSNSDTGDLQESLKHGLTPIGAGLPDRHGSPIPARGRLVMLPKVETEALGLARSHGEQGQMPENMQVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKGLPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMGYSYMDSYQTSSPASIPHLILELLKCEPDEPQVQA... | acinar cell differentiation bile acid metabolic process calcineurin-mediated signaling cellular response to leukemia inhibitory factor cholesterol homeostasis embryo development ending in birth or egg hatching homeostatic process hormone-mediated signaling pathway pancreas morphogenesis positive regulation of DNA-templ... |
double-strand break repair via homologous recombination double-strand break repair via nonhomologous end joining proteasome-mediated ubiquitin-dependent protein catabolic process protein K63-linked deubiquitination regulation of proteasomal protein catabolic process response to ethanol ubiquitin-dependent protein catab... | cytosol; cytosolic proteasome complex; extracellular region; ficolin-1-rich granule lumen; nucleoplasm; nucleus; proteasome accessory complex; proteasome complex; proteasome regulatory particle, lid subcomplex; secretory granule lumen | endopeptidase activator activity K63-linked deubiquitinase activity metal ion binding metal-dependent deubiquitinase activity metallopeptidase activity proteasome binding | Homo sapiens | 3D-structure Direct protein sequencing DNA damage DNA repair Hydrolase Metal-binding Metalloprotease Phosphoprotein Protease Proteasome Reference proteome Ubl conjugation pathway Zinc | MDRLLRLGGG | MDRLLRLGGGMPGLGQGPPTDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKHNESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCLAAMLDTVVFK | double-strand break repair via homologous recombination double-strand break repair via nonhomologous end joining proteasome-mediated ubiquitin-dependent protein catabolic process protein K63-linked deubiquitination regulation of proteasomal protein catabolic process response to ethanol ubiquitin-dependent protein catab... |
negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding positive regulation of transcription by RNA polymerase II ribosome biogenesis | cytoplasm; nucleolus; nucleoplasm | DNA binding preribosome binding zinc ion binding | Homo sapiens | 3D-structure Cytoplasm DNA-binding Metal-binding Nucleus Reference proteome Ribosome biogenesis Transcription Transcription regulation Zinc Zinc-finger | MGRSRRTGAH | MGRSRRTGAHRAHSLARQMKAKRRRPDLDEIHRELRPQGSARPQPDPNAEFDPDLPGGGLHRCLACARYFIDSTNLKTHFRSKDHKKRLKQLSVEPYSQEEAERAAGMGSYVPPRRLAVPTEVSTEVPEMDTST | negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding positive regulation of transcription by RNA polymerase II ribosome biogenesis cytoplasm; nucleolus; nucleoplasm DNA binding preribosome binding zinc ion binding Homo sapiens 3D-structure Cytoplasm DNA-binding Metal-binding Nucleus ... |
cytoskeleton organization endocytosis endosome to lysosome transport lipid tube assembly negative regulation of amyloid-beta formation negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process negative regulation of calcium ion transmembrane transport via high v... | actin cytoskeleton; axon; axon initial segment; axon terminus; cerebellar mossy fiber; cytoplasm; cytosol; dendrite; endosome; extrinsic component of synaptic vesicle membrane; glutamatergic synapse; I band; lipid tube; membrane; node of Ranvier; nuclear envelope; nucleus; plasma membrane; RNA polymerase II transcripti... | actin filament binding aspartic-type endopeptidase inhibitor activity clathrin binding GTPase binding identical protein binding phospholipid binding protease binding protein-folding chaperone binding RNA polymerase binding tau protein binding | Homo sapiens | 3D-structure Acetylation Alternative splicing Cell membrane Coiled coil Cytoplasm Developmental protein Differentiation Disease variant Endocytosis Endosome Host-virus interaction Membrane Nucleus Phosphoprotein Reference proteome SH3 domain | MAEMGSKGVT | MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEKAAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAG... | cytoskeleton organization endocytosis endosome to lysosome transport lipid tube assembly negative regulation of amyloid-beta formation negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process negative regulation of calcium ion transmembrane transport via high v... |
bicellular tight junction assembly calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules cell adhesion cell-cell junction assembly establishment of blood-retinal barrier face morphogenesis learning maintenance of blood-brain barrier myelination negative regulation of angiogenesis negative r... | apicolateral plasma membrane; bicellular tight junction; cell junction; cell-cell junction; lateral plasma membrane; membrane; paranode region of axon; plasma membrane; Schmidt-Lanterman incisure; tight junction | identical protein binding structural molecule activity | Homo sapiens | Cell junction Cell membrane Membrane Reference proteome Tight junction Transmembrane Transmembrane helix | MGSAALEILG | MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALTGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCLLCCGAWVCTGRPDLSFPVKYSAPRRPTATGDYDKKNYV | bicellular tight junction assembly calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules cell adhesion cell-cell junction assembly establishment of blood-retinal barrier face morphogenesis learning maintenance of blood-brain barrier myelination negative regulation of angiogenesis negative r... |
NLS-bearing protein import into nucleus protein import into nucleus protein-containing complex assembly viral entry into host cell viral penetration into host nucleus | cytosol; host cell; NLS-dependent protein nuclear import complex; nuclear pore; nucleoplasm; nucleus | nuclear import signal receptor activity nuclear localization sequence binding | Homo sapiens | Acetylation Cytoplasm Disease variant Hereditary spastic paraplegia Host-virus interaction Neurodegeneration Nucleus Phosphoprotein Protein transport Reference proteome Repeat Transport Viral penetration into host nucleus Virus entry into host cell | MAENPSLENH | MAENPSLENHRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQNVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQ... | NLS-bearing protein import into nucleus protein import into nucleus protein-containing complex assembly viral entry into host cell viral penetration into host nucleus cytosol; host cell; NLS-dependent protein nuclear import complex; nuclear pore; nucleoplasm; nucleus nuclear import signal receptor activity nuclear loca... |
axonogenesis establishment of Golgi localization establishment or maintenance of cell polarity Golgi localization Golgi reassembly intrinsic apoptotic signaling pathway in response to hydrogen peroxide positive regulation of axonogenesis positive regulation of stress-activated MAPK cascade protein autophosphorylation p... | cytoplasm; extracellular exosome; Golgi apparatus | ATP binding metal ion binding protein homodimerization activity protein kinase activity protein serine kinase activity protein serine/threonine kinase activity | Homo sapiens | 3D-structure Alternative splicing ATP-binding Cytoplasm Golgi apparatus Kinase Magnesium Metal-binding Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MAHLRGFANQ | MAHLRGFANQHSRVDPEELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNSPPTLEGQHSKPFKEFVEACLNKDPRFRPTAKELLKHKFITRYTKKTSFLTELIDRYKRWKSEGHGEESSSEDSDIDGEAEDGEQGPIWT... | axonogenesis establishment of Golgi localization establishment or maintenance of cell polarity Golgi localization Golgi reassembly intrinsic apoptotic signaling pathway in response to hydrogen peroxide positive regulation of axonogenesis positive regulation of stress-activated MAPK cascade protein autophosphorylation p... |
arachidonic acid metabolic process fatty acid catabolic process monoacylglycerol catabolic process positive regulation of vasoconstriction | cytoskeleton; endoplasmic reticulum membrane; organelle membrane | acylglycerol lipase activity amidase activity fatty acid amide hydrolase activity identical protein binding phospholipid binding | Homo sapiens | Cytoplasm Cytoskeleton Direct protein sequencing Hydrolase Lipid degradation Lipid metabolism Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix | MVQYELWAAL | MVQYELWAALPGASGVALACCFVAAAVALRWSGRRTARGAVVRARQRQRAGLENMDRAAQRFRLQNPDLDSEALLALPLPQLVQKLHSRELAPEAVLFTYVGKAWEVNKGTNCVTSYLADCETQLSQAPRQGLLYGVPVSLKECFTYKGQDSTLGLSLNEGVPAECDSVVVHVLKLQGAVPFVHTNVPQSMFSYDCSNPLFGQTVNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSSFCGICGLKPTGNRLSKSGLKGCVYGQEAVRLSVGPMARDVESLALCLRALLCEDMFRLDPTVPPLPFREEVYT... | arachidonic acid metabolic process fatty acid catabolic process monoacylglycerol catabolic process positive regulation of vasoconstriction cytoskeleton; endoplasmic reticulum membrane; organelle membrane acylglycerol lipase activity amidase activity fatty acid amide hydrolase activity identical protein binding phosphol... |
angiogenesis cell redox homeostasis endothelium development integrin activation negative regulation of angiogenesis negative regulation of endothelial cell apoptotic process negative regulation of endothelial cell migration negative regulation of endothelial cell proliferation regulation of angiogenesis regulation of e... | cell-cell junction; cytoplasm; cytoskeleton; extracellular space; plasma membrane; protein-containing complex | GTPase regulator activity microtubule binding phosphatidylinositol-4,5-bisphosphate binding | Homo sapiens | 3D-structure Alternative splicing Angiogenesis ANK repeat Cell junction Cell membrane Cytoplasm Cytoskeleton Disease variant Membrane Reference proteome Repeat | MGNPENIEDA | MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQGNSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDNTKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRPSPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQYTNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSD... | angiogenesis cell redox homeostasis endothelium development integrin activation negative regulation of angiogenesis negative regulation of endothelial cell apoptotic process negative regulation of endothelial cell migration negative regulation of endothelial cell proliferation regulation of angiogenesis regulation of e... |
cell population proliferation maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) regulation of cell cycle ribosomal large subunit biogenesis rRNA processing | chromosome; cytosol; membrane; nucleolus; nucleoplasm; PeBoW complex; preribosome, large subunit precursor | ribonucleoprotein complex binding RNA binding | Homo sapiens | 3D-structure Acetylation Alternative splicing Chromosome Isopeptide bond Nucleus Reference proteome Ribosome biogenesis rRNA processing Ubl conjugation | MGGLEKKKYE | MGGLEKKKYERGSATNYITRNKARKKLQLSLADFRRLCILKGIYPHEPKHKKKVNKGSTAARTFYLIKDIRFLLHEPIVNKFREYKVFVRKLRKAYGKSEWNTVERLKDNKPNYKLDHIIKERYPTFIDALRDLDDALSMCFLFSTFPRTGKCHVQTIQLCRRLTVEFMHYIIAARALRKVFLSIKGIYYQAEVLGQPIVWITPYAFSHDHPTDVDYRVMATFTEFYTTLLGFVNFRLYQLLNLHYPPKLEGQAQAEAKAGEGTYALDSESCMEKLAALSASLARVVVPATEEEAEVDEFPTDGEMSAQEEDRRKELEAQ... | cell population proliferation maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) regulation of cell cycle ribosomal large subunit biogenesis rRNA processing chromosome; cytosol; membrane; nucl... |
adaptive immune memory response involving T cells and B cells regulation of cell growth T cell mediated cytotoxicity | Golgi membrane; secretory granule | peptidase activator activity involved in apoptotic process | Homo sapiens | Alternative splicing Apoptosis Coiled coil Golgi apparatus Membrane Phosphoprotein Reference proteome Signal-anchor Transmembrane Transmembrane helix | MAITQFRLFK | MAITQFRLFKFCTCLATVFSFLKRLICRSGRGRKLSGDQITLPTTVDYSSVPKQTDVEEWTSWDEDAPTSVKIEGGNGNVATQQNSLEQLEPDYFKDMTPTIRKTQKIVIKKREPLNFGIPDGSTGFSSRLAATQDLPFIHQSSELGDLDTWQENTNAWEEEEDAAWQAEEVLRQQKLADREKRAAEQQRKKMEKEAQRLMKKEQNKIGVKLS | adaptive immune memory response involving T cells and B cells regulation of cell growth T cell mediated cytotoxicity Golgi membrane; secretory granule peptidase activator activity involved in apoptotic process Homo sapiens Alternative splicing Apoptosis Coiled coil Golgi apparatus Membrane Phosphoprotein Reference prot... |
actin cytoskeleton organization chemical synaptic transmission intracellular signal transduction negative regulation of receptor internalization negative regulation of transcription by RNA polymerase II positive regulation of cell growth positive regulation of cell migration positive regulation of cell population proli... | adherens junction; azurophil granule lumen; blood microparticle; cytoplasm; cytoskeleton; cytosol; endoplasmic reticulum membrane; extracellular exosome; extracellular region; extracellular space; extracellular vesicle; focal adhesion; interleukin-5 receptor complex; melanosome; membrane; membrane raft; nuclear membran... | cell adhesion molecule binding cytoskeletal anchor activity ephrin receptor binding frizzled binding growth factor binding identical protein binding interleukin-5 receptor binding ionotropic glutamate receptor binding neurexin family protein binding phosphatidylinositol-4,5-bisphosphate binding protein heterodimerizati... | Homo sapiens | 3D-structure Acetylation Alternative splicing Cell junction Cell membrane Cytoplasm Cytoskeleton Direct protein sequencing Endoplasmic reticulum Lipid-binding Membrane Nucleus Phosphoprotein Reference proteome Repeat Secreted | MSLYPSLEDL | MSLYPSLEDLKVDKVIQAQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLSLNEEEIRANVAVVSGAPLQGQLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKDQDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV | actin cytoskeleton organization chemical synaptic transmission intracellular signal transduction negative regulation of receptor internalization negative regulation of transcription by RNA polymerase II positive regulation of cell growth positive regulation of cell migration positive regulation of cell population proli... |
maturation of SSU-rRNA ribosomal small subunit biogenesis RNA processing RNA splicing RNA splicing, via transesterification reactions | chromosome; Mpp10 complex; nucleolus; nucleoplasm; small-subunit processome; sno(s)RNA-containing ribonucleoprotein complex | RNA binding | Homo sapiens | 3D-structure Acetylation Chromosome Coiled coil Isopeptide bond Nucleus Phosphoprotein Reference proteome Ribonucleoprotein Ribosome biogenesis rRNA processing Ubl conjugation | MAPQVWRRRT | MAPQVWRRRTLERCLTEVGKATGRPECFLTIQEGLASKFTSLTKVLYDFNKILENGRIHGSPLQKLVIENFDDEQIWQQLELQNEPILQYFQNAVSETINDEDISLLPESEEQEREEDGSEIEADDKEDLEDLEEEEVSDMGNDDPEMGERAENSSKSDLRKSPVFSDEDSDLDFDISKLEQQSKVQNKGQGKPREKSIVDDKFFKLSEMEAYLENIEKEEERKDDNDEEEEDIDFFEDIDSDEDEGGLFGSKKLKSGKSSRNLKYKDFFDPVESDEDITNVHDDELDSNKEDDEIAEEEAEELSISETDEDDDLQENED... | maturation of SSU-rRNA ribosomal small subunit biogenesis RNA processing RNA splicing RNA splicing, via transesterification reactions chromosome; Mpp10 complex; nucleolus; nucleoplasm; small-subunit processome; sno(s)RNA-containing ribonucleoprotein complex RNA binding Homo sapiens 3D-structure Acetylation Chromosome C... |
ribosomal small subunit biogenesis rRNA processing | box C/D RNP complex; cytoplasm; fibrillar center; membrane; nucleolus; nucleoplasm; pre-snoRNP complex; small-subunit processome; sno(s)RNA-containing ribonucleoprotein complex | cadherin binding histone methyltransferase binding RNA binding snoRNA binding | Homo sapiens | 3D-structure Acetylation Cytoplasm Direct protein sequencing Isopeptide bond Methylation Neurodegeneration Nucleus Phosphoprotein Reference proteome Ribonucleoprotein Ribosome biogenesis Spinocerebellar ataxia Ubl conjugation | MVLLHVLFEH | MVLLHVLFEHAVGYALLALKEVEEISLLQPQVEESVLNLGKFHSIVRLVAFCPFASSQVALENANAVSEGVVHEDLRLLLETHLPSKKKKVLLGVGDPKIGAAIQEELGYNCQTGGVIAEILRGVRLHFHNLVKGLTDLSACKAQLGLGHSYSRAKVKFNVNRVDNMIIQSISLLDQLDKDINTFSMRVREWYGYHFPELVKIINDNATYCRLAQFIGNRRELNEDKLEKLEELTMDGAKAKAILDASRSSMGMDISAIDLINIESFSSRVVSLSEYRQSLHTYLRSKMSQVAPSLSALIGEAVGARLIAHAGSLTNLAK... | ribosomal small subunit biogenesis rRNA processing box C/D RNP complex; cytoplasm; fibrillar center; membrane; nucleolus; nucleoplasm; pre-snoRNP complex; small-subunit processome; sno(s)RNA-containing ribonucleoprotein complex cadherin binding histone methyltransferase binding RNA binding snoRNA binding Homo sapiens 3... |
calcium-mediated signaling cell chemotaxis G protein-coupled receptor signaling pathway immune response inflammatory response positive regulation of cytosolic calcium ion concentration viral genome replication | external side of plasma membrane; plasma membrane | C-C chemokine binding C-C chemokine receptor activity C-X-C chemokine receptor activity coreceptor activity G protein-coupled receptor activity | Homo sapiens | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MAEHDYHEDY | MAEHDYHEDYGFSSFNDSSQEEHQDFLQFSKVFLPCMYLVVFVCGLVGNSLVLVISIFYHKLQSLTDVFLVNLPLADLVFVCTLPFWAYAGIHEWVFGQVMCKSLLGIYTINFYTSMLILTCITVDRFIVVVKATKAYNQQAKRMTWGKVTSLLIWVISLLVSLPQIIYGNVFNLDKLICGYHDEAISTVVLATQMTLGFFLPLLTMIVCYSVIIKTLLHAGGFQKHRSLKIIFLVMAVFLLTQMPFNLMKFIRSTHWEYYAMTSFHYTIMVTEAIAYLRACLNPVLYAFVSLKFRKNFWKLVKDIGCLPYLGVSHQWKS... | calcium-mediated signaling cell chemotaxis G protein-coupled receptor signaling pathway immune response inflammatory response positive regulation of cytosolic calcium ion concentration viral genome replication external side of plasma membrane; plasma membrane C-C chemokine binding C-C chemokine receptor activity C-X-C ... |
innate immune response RNA catabolic process | azurophil granule lumen; endoplasmic reticulum lumen; extracellular exosome; extracellular region; extracellular space; lysosomal lumen; lysosome; mitochondrial intermembrane space | ribonuclease T2 activity RNA binding RNA endonuclease activity RNA nuclease activity | Homo sapiens | 3D-structure Alternative splicing Disease variant Disulfide bond Endonuclease Endoplasmic reticulum Glycoprotein Hydrolase Immunity Innate immunity Lyase Lysosome Mitochondrion Nuclease Reference proteome Secreted Signal | MRPAALRGAL | MRPAALRGALLGCLCLALLCLGGADKRLRDNHEWKKLIMVQHWPETVCEKIQNDCRDPPDYWTIHGLWPDKSEGCNRSWPFNLEEIKDLLPEMRAYWPDVIHSFPNRSRFWKHEWEKHGTCAAQVDALNSQKKYFGRSLELYRELDLNSVLLKLGIKPSINYYQVADFKDALARVYGVIPKIQCLPPSQDEEVQTIGQIELCLTKQDQQLQNCTEPGEQPSPKQEVWLANGAAESRGLRVCEDGPVFYPPPKKTKH | innate immune response RNA catabolic process azurophil granule lumen; endoplasmic reticulum lumen; extracellular exosome; extracellular region; extracellular space; lysosomal lumen; lysosome; mitochondrial intermembrane space ribonuclease T2 activity RNA binding RNA endonuclease activity RNA nuclease activity Homo sapi... |
blastocyst formation marginal zone B cell differentiation pattern specification process positive regulation of Notch signaling pathway regulation of Notch signaling pathway | extracellular space; Golgi membrane | metal ion binding O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity | Homo sapiens | Alternative splicing Developmental protein Disulfide bond Glycoprotein Glycosyltransferase Golgi apparatus Manganese Membrane Metal-binding Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix | MQCRLPRGLA | MQCRLPRGLAGALLTLLCMGLLCLRYHLNLSPQRVQGTPELSQPNPGPPKLQLHDVFIAVKTTRAFHRLRLELLLDTWVSRTREQTFVFTDSPDKGLQERLGSHLVVTNCSAEHSHPALSCKMAAEFDTFLASGLRWFCHVDDDNYVNPRALLQLLRAFPLARDVYVGRPSLNRPIHASEPQPHNRTRLVQFWFATGGAGFCINRKLALKMAPWASGSRFMDTSALIRLPDDCTMGYIIECKLGGRLQPSPLFHSHLETLQLLRTAQLPEQVTLSYGVFEGKLNVIKLQGPFSPEEDPSRFRSLHCLLYPDTPWCPQLGA... | blastocyst formation marginal zone B cell differentiation pattern specification process positive regulation of Notch signaling pathway regulation of Notch signaling pathway extracellular space; Golgi membrane metal ion binding O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity Homo sapiens Alternative spl... |
calcium-mediated signaling cell chemotaxis immune response inflammatory response intracellular signal transduction positive regulation of cytosolic calcium ion concentration | actin filament; cytosol; early endosome; external side of plasma membrane; intracellular membrane-bounded organelle; nuclear membrane; nucleoplasm; plasma membrane; recycling endosome | C-C chemokine binding C-C chemokine receptor activity chemokine receptor activity scavenger receptor activity | Homo sapiens | Cell membrane Disulfide bond Endosome G-protein coupled receptor Glycoprotein Inflammatory response Membrane Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MAATASPQPL | MAATASPQPLATEDADSENSSFYYYDYLDEVAFMLCRKDAVVSFGKVFLPVFYSLIFVLGLSGNLLLLMVLLRYVPRRRMVEIYLLNLAISNLLFLVTLPFWGISVAWHWVFGSFLCKMVSTLYTINFYSGIFFISCMSLDKYLEIVHAQPYHRLRTRAKSLLLATIVWAVSLAVSIPDMVFVQTHENPKGVWNCHADFGGHGTIWKLFLRFQQNLLGFLLPLLAMIFFYSRIGCVLVRLRPAGQGRALKIAAALVVAFFVLWFPYNLTLFLHTLLDLQVFGNCEVSQHLDYALQVTESIAFLHCCFSPILYAFSSHRFR... | calcium-mediated signaling cell chemotaxis immune response inflammatory response intracellular signal transduction positive regulation of cytosolic calcium ion concentration actin filament; cytosol; early endosome; external side of plasma membrane; intracellular membrane-bounded organelle; nuclear membrane; nucleoplasm... |
chloride transmembrane transport | chloride channel complex; GABA-A receptor complex; neuron projection; postsynaptic membrane; synapse | chloride channel activity extracellular ligand-gated monoatomic ion channel activity GABA-A receptor activity neurotransmitter receptor activity | Homo sapiens | Cell membrane Chloride Chloride channel Disulfide bond Glycoprotein Ion channel Ion transport Membrane Postsynaptic cell membrane Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MNYSLHLAFV | MNYSLHLAFVCLSLFTERMCIQGSQFNVEVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYLRQRWMDQRLVFEGNKSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIERYFTLVTRSQQETGNYTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWISLDSVPARTCIGVTTVLSMTTLMIGSRTSLPNTNCFIKAIDVYLGICFSFVFGA... | chloride transmembrane transport chloride channel complex; GABA-A receptor complex; neuron projection; postsynaptic membrane; synapse chloride channel activity extracellular ligand-gated monoatomic ion channel activity GABA-A receptor activity neurotransmitter receptor activity Homo sapiens Cell membrane Chloride Chlor... |
cell surface pattern recognition receptor signaling pathway complement activation, lectin pathway G protein-coupled receptor signaling pathway negative regulation of viral entry into host cell positive regulation of interleukin-8 production positive regulation of opsonization protein localization to cell surface proteo... | collagen trimer; collagen-containing extracellular matrix; external side of plasma membrane; extracellular region; extracellular space; ficolin-1-rich granule lumen; plasma membrane; secretory granule lumen; serine-type endopeptidase complex | antigen binding carbohydrate binding carbohydrate derivative binding G protein-coupled receptor binding metal ion binding pattern recognition receptor activity sialic acid binding signaling receptor binding | Homo sapiens | 3D-structure Calcium Cell membrane Collagen Direct protein sequencing Disulfide bond Glycoprotein Immunity Innate immunity Lectin Membrane Metal-binding Reference proteome Repeat Secreted Signal | MELSGATMAR | MELSGATMARGLAVLLVLFLHIKNLPAQAADTCPEVKVVGLEGSDKLTILRGCPGLPGAPGPKGEAGVIGERGERGLPGAPGKAGPVGPKGDRGEKGMRGEKGDAGQSQSCATGPRNCKDLLDRGYFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDWAAYKQGFGSQLGEFWLGNDNIHALTAQGSSELRVDLVDFEGNHQFAKYKSFKVADEAEKYKLVLGAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNGLYLMGPHESYANGINWSAAKGYKYSYKVSE... | cell surface pattern recognition receptor signaling pathway complement activation, lectin pathway G protein-coupled receptor signaling pathway negative regulation of viral entry into host cell positive regulation of interleukin-8 production positive regulation of opsonization protein localization to cell surface proteo... |
cellular response to reactive oxygen species peroxisome organization proteasome-mediated ubiquitin-dependent protein catabolic process protein import into peroxisome matrix protein import into peroxisome matrix, receptor recycling protein import into peroxisome matrix, substrate release protein monoubiquitination prote... | cytosol; peroxisomal importomer complex; peroxisomal membrane; peroxisome | protein transmembrane transporter activity ubiquitin ligase activator activity ubiquitin-protein transferase activity zinc ion binding | Homo sapiens | Disease variant Membrane Metal-binding Peroxisome Peroxisome biogenesis disorder Protein transport Reference proteome Transmembrane Transmembrane helix Transport Ubl conjugation pathway Zellweger syndrome Zinc Zinc-finger | MAEHGAHFTA | MAEHGAHFTAASVADDQPSIFEVVAQDSLMTAVRPALQHVVKVLAESNPTHYGFLWRWFDEIFTLLDLLLQQHYLSRTSASFSENFYGLKRIVMGDTHKSQRLASAGLPKQQLWKSIMFLVLLPYLKVKLEKLVSSLREEDEYSIHPPSSRWKRFYRAFLAAYPFVNMAWEGWFLVQQLRYILGKAQHHSPLLRLAGVQLGRLTVQDIQALEHKPAKASMMQQPARSVSEKINSALKKAVGGVALSLSTGLSVGVFFLQFLDWWYSSENQETIKSLTALPTPPPPVHLDYNSDSPLLPKMKTVCPLCRKTRVNDTVLATS... | cellular response to reactive oxygen species peroxisome organization proteasome-mediated ubiquitin-dependent protein catabolic process protein import into peroxisome matrix protein import into peroxisome matrix, receptor recycling protein import into peroxisome matrix, substrate release protein monoubiquitination prote... |
monoatomic anion transport phosphate-containing compound metabolic process sodium ion transport | apical plasma membrane; membrane; plasma membrane | sodium:phosphate symporter activity transmembrane transporter activity urate transmembrane transporter activity | Homo sapiens | Alternative splicing Cell membrane Glycoprotein Ion transport Membrane Reference proteome Sodium Sodium transport Symport Transmembrane Transmembrane helix Transport | MDGKPATRKG | MDGKPATRKGPDFCSLRYGLALIMHFSNFTMITQRVSLSIAIIAMVNTTQQQGLSNASTEGPVADAFNNSSISIKEFDTKASVYQWSPETQGIIFSSINYGIILTLIPSGYLAGIFGAKKMLGAGLLISSLLTLFTPLAADFGVILVIMVRTVQGMAQGMAWTGQFTIWAKWAPPLERSKLTTIAGSGSAFGSFIILCVGGLISQALSWPFIFYIFGSTGCVCCLLWFTVIYDDPMHHPCISVREKEHILSSLAQQPSSPGRAVPIKAMVTCLPLWAIFLGFFSHFWLCTIILTYLPTYISTLLHVNIRDSGVLSSLPFI... | monoatomic anion transport phosphate-containing compound metabolic process sodium ion transport apical plasma membrane; membrane; plasma membrane sodium:phosphate symporter activity transmembrane transporter activity urate transmembrane transporter activity Homo sapiens Alternative splicing Cell membrane Glycoprotein I... |
digestion monocyte differentiation transcription by RNA polymerase II | cytoplasm; cytosol; nuclear body; nucleoplasm; nucleus | metal ion binding quercetin 2,3-dioxygenase activity transcription coregulator activity | Homo sapiens | 3D-structure Cytoplasm Dioxygenase Iron Metal-binding Nucleus Oxidoreductase Reference proteome Transcription Transcription regulation | MGSSKKVTLS | MGSSKKVTLSVLSREQSEGVGARVRRSIGRPELKNLDPFLLFDEFKGGRPGGFPDHPHRGFETVSYLLEGGSMAHEDFCGHTGKMNPGDLQWMTAGRGILHAEMPCSEEPAHGLQLWVNLRSSEKMVEPQYQELKSEEIPKPSKDGVTVAVISGEALGIKSKVYTRTPTLYLDFKLDPGAKHSQPIPKGWTSFIYTISGDVYIGPDDAQQKIEPHHTAVLGEGDSVQVENKDPKRSHFVLIAGEPLREPVIQHGPFVMNTNEEISQAILDFRNAKNGFERAKTWKSKIGN | digestion monocyte differentiation transcription by RNA polymerase II cytoplasm; cytosol; nuclear body; nucleoplasm; nucleus metal ion binding quercetin 2,3-dioxygenase activity transcription coregulator activity Homo sapiens 3D-structure Cytoplasm Dioxygenase Iron Metal-binding Nucleus Oxidoreductase Reference proteom... |
cell-cell signaling cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to type II interferon chemokine-mediated signaling pathway chemotaxis eosinophil chemotaxis G protein-coupled receptor signaling pathway immune response inflammatory response lymphocyte chemotaxis monocyt... | extracellular region; extracellular space | CCR chemokine receptor binding chemokine activity | Homo sapiens | Chemotaxis Cytokine Direct protein sequencing Disulfide bond Reference proteome Secreted Signal | MDRLQTALLV | MDRLQTALLVVLVLLAVALQATEAGPYGANMEDSVCCRDYVRYRLPLRVVKHFYWTSDSCPRPGVVLLTFRDKEICADPRVPWVKMILNKLSQ | cell-cell signaling cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to type II interferon chemokine-mediated signaling pathway chemotaxis eosinophil chemotaxis G protein-coupled receptor signaling pathway immune response inflammatory response lymphocyte chemotaxis monocyt... |
endochondral ossification ether lipid biosynthetic process fatty acid beta-oxidation neuron migration peroxisome organization protein import into peroxisome matrix protein targeting to peroxisome | cytosol; peroxisomal matrix; peroxisomal membrane; peroxisome | enzyme binding peroxisome matrix targeting signal-2 binding protein homodimerization activity | Homo sapiens | Alternative splicing Cataract Cytoplasm Deafness Disease variant Ichthyosis Peroxisome Peroxisome biogenesis disorder Protein transport Reference proteome Repeat Retinitis pigmentosa Rhizomelic chondrodysplasia punctata Transport WD repeat | MSAVCGGAAR | MSAVCGGAARMLRTPGRHGYAAEFSPYLPGRLACATAQHYGIAGCGTLLILDPDEAGLRLFRSFDWNDGLFDVTWSENNEHVLITCSGDGSLQLWDTAKAAGPLQVYKEHAQEVYSVDWSQTRGEQLVVSGSWDQTVKLWDPTVGKSLCTFRGHESIIYSTIWSPHIPGCFASASGDQTLRIWDVKAAGVRIVIPAHQAEILSCDWCKYNENLLVTGAVDCSLRGWDLRNVRQPVFELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWNFSKPDSLLETVEHHTEFTCGLDFSLQSPTQVADCSWDETIKIYDPACLT... | endochondral ossification ether lipid biosynthetic process fatty acid beta-oxidation neuron migration peroxisome organization protein import into peroxisome matrix protein targeting to peroxisome cytosol; peroxisomal matrix; peroxisomal membrane; peroxisome enzyme binding peroxisome matrix targeting signal-2 binding pr... |
dopamine secretion gene expression NLS-bearing protein import into nucleus protein import into nucleus | cytosol; NLS-dependent protein nuclear import complex; nuclear membrane; nuclear pore; nucleoplasm; nucleus | nuclear import signal receptor activity nuclear localization sequence binding | Homo sapiens | 3D-structure Acetylation Cytoplasm Host-virus interaction Nucleus Phosphoprotein Protein transport Reference proteome Repeat Transport | MADNEKLDNQ | MADNEKLDNQRLKNFKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPHEDICEDSDIDGDYRVQNTSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQ... | dopamine secretion gene expression NLS-bearing protein import into nucleus protein import into nucleus cytosol; NLS-dependent protein nuclear import complex; nuclear membrane; nuclear pore; nucleoplasm; nucleus nuclear import signal receptor activity nuclear localization sequence binding Homo sapiens 3D-structure Acety... |
calcium ion transport negative regulation of ATPase-coupled calcium transmembrane transporter activity negative regulation of calcium ion binding negative regulation of calcium ion import negative regulation of calcium ion transmembrane transporter activity negative regulation of catalytic activity negative regulation ... | membrane; sarcoplasmic reticulum; sarcoplasmic reticulum membrane | ATPase binding enzyme inhibitor activity | Homo sapiens | 3D-structure Endoplasmic reticulum Membrane Reference proteome Sarcoplasmic reticulum Transmembrane Transmembrane helix | MGINTRELFL | MGINTRELFLNFTIVLITVILMWLLVRSYQY | calcium ion transport negative regulation of ATPase-coupled calcium transmembrane transporter activity negative regulation of calcium ion binding negative regulation of calcium ion import negative regulation of calcium ion transmembrane transporter activity negative regulation of catalytic activity negative regulation ... |
innate immune response negative regulation of defense response to virus positive regulation of autophagy positive regulation of canonical NF-kappaB signal transduction positive regulation of DNA-binding transcription factor activity positive regulation of NF-kappaB transcription factor activity positive regulation of v... | cytoplasm; cytosol; nucleoplasm | protein homodimerization activity protein kinase binding transcription coactivator activity ubiquitin protein ligase activity zinc ion binding | Homo sapiens | Cytoplasm Immunity Innate immunity Metal-binding Phosphoprotein Reference proteome Transferase Ubl conjugation pathway Zinc Zinc-finger | MASTTSTKKM | MASTTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCPQCRAPFHMDSLRPNKQLGSLIEALKETDQEMSCEEHGEQFHLFCEDEGQLICWRCERAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELEEKCQGSAQKLLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYFDVKKMLRSHQVSVTLDPDTAHHELILSEDRRQVTRGYTQ... | innate immune response negative regulation of defense response to virus positive regulation of autophagy positive regulation of canonical NF-kappaB signal transduction positive regulation of DNA-binding transcription factor activity positive regulation of NF-kappaB transcription factor activity positive regulation of v... |
G1/S transition of mitotic cell cycle negative regulation of fat cell proliferation positive regulation of cell population proliferation positive regulation of transcription by RNA polymerase II positive regulation of vascular associated smooth muscle cell apoptotic process protein import into nucleus regulation of tra... | chromatin; nucleoplasm; nucleus; RNA polymerase II transcription regulator complex | cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific protein dimerization activity RNA poly... | Homo sapiens | Activator Alternative splicing Cell cycle DNA-binding Nucleus Reference proteome Transcription Transcription regulation | MRKGIQPALE | MRKGIQPALEQYLVTAGGGEGAAVVAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQILTTNTSTTSCSSSLQSGAVAAGPLLPSAPGAEQTAGSLLYTTPHGPSSRAGLLQQPPALGRGGSGGGGGPPAKRRLELGESGHQYLSDGLKTPKGKGRAALRSPDSPKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDITNVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCTLDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVIVVKA... | G1/S transition of mitotic cell cycle negative regulation of fat cell proliferation positive regulation of cell population proliferation positive regulation of transcription by RNA polymerase II positive regulation of vascular associated smooth muscle cell apoptotic process protein import into nucleus regulation of tra... |
COPII vesicle coating G1/S transition of mitotic cell cycle innate immune response negative regulation of cGAS/STING signaling pathway protein dephosphorylation | cytoplasm; cytosol; mitochondrion; nucleoplasm | metal ion binding myosin phosphatase activity protein serine/threonine phosphatase activity | Homo sapiens | Acetylation Alternative splicing Cell cycle Cytoplasm Direct protein sequencing Hydrolase Immunity Innate immunity Manganese Metal-binding Mitochondrion Protein phosphatase Reference proteome | MAPLDLDKYV | MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYFL | COPII vesicle coating G1/S transition of mitotic cell cycle innate immune response negative regulation of cGAS/STING signaling pathway protein dephosphorylation cytoplasm; cytosol; mitochondrion; nucleoplasm metal ion binding myosin phosphatase activity protein serine/threonine phosphatase activity Homo sapiens Acetyla... |
CTP biosynthetic process GTP biosynthetic process lipid transport nucleoside metabolic process phosphorylation UTP biosynthetic process | mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrial matrix; mitochondrion | ATP binding cardiolipin binding metal ion binding nucleoside diphosphate kinase activity | Homo sapiens | 3D-structure Alternative splicing ATP-binding Direct protein sequencing Kinase Lipid-binding Magnesium Membrane Metal-binding Mitochondrion Nucleotide metabolism Nucleotide-binding Reference proteome Transferase Transit peptide | MGGLFWRSAL | MGGLFWRSALRGLRCGPRAPGPSLLVRHGSGGPSWTRERTLVAVKPDGVQRRLVGDVIQRFERRGFTLVGMKMLQAPESVLAEHYQDLRRKPFYPALIRYMSSGPVVAMVWEGYNVVRASRAMIGHTDSAEAAPGTIRGDFSVHISRNVIHASDSVEGAQREIQLWFQSSELVSWADGGQHSSIHPA | CTP biosynthetic process GTP biosynthetic process lipid transport nucleoside metabolic process phosphorylation UTP biosynthetic process mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrial matrix; mitochondrion ATP binding cardiolipin binding metal ion binding nucleoside diphosphate kinase act... |
catabolic process prostaglandin metabolic process xenobiotic metabolic process | endoplasmic reticulum; endoplasmic reticulum lumen; intracellular membrane-bounded organelle | carboxylesterase activity carboxylic ester hydrolase activity methylumbelliferyl-acetate deacetylase activity | Homo sapiens | Alternative initiation Alternative splicing Direct protein sequencing Disulfide bond Endoplasmic reticulum Glycoprotein Hydrolase Lipid metabolism Pyrrolidone carboxylic acid Reference proteome Serine esterase Signal | MRLHRLRARL | MRLHRLRARLSAVACGLLLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAINKPFKMIPGVVDGVFLP... | catabolic process prostaglandin metabolic process xenobiotic metabolic process endoplasmic reticulum; endoplasmic reticulum lumen; intracellular membrane-bounded organelle carboxylesterase activity carboxylic ester hydrolase activity methylumbelliferyl-acetate deacetylase activity Homo sapiens Alternative initiation Al... |
learning or memory mannose metabolic process oligosaccharide catabolic process protein deglycosylation protein modification process | azurophil granule lumen; extracellular exosome; extracellular region; extracellular space; intracellular membrane-bounded organelle; lysosomal lumen; lysosome; nucleoplasm | alpha-mannosidase activity carbohydrate binding metal ion binding | Homo sapiens | Alternative splicing Direct protein sequencing Disease variant Disulfide bond Glycoprotein Glycosidase Hydrolase Lysosome Metal-binding Reference proteome Signal Zinc Zymogen | MGAYARASGV | MGAYARASGVCARGCLDSAGPWTMSRALRPPLPPLCFFLLLLAAAGARAGGYETCPTVQPNMLNVHLLPHTHDDVGWLKTVDQYFYGIKNDIQHAGVQYILDSVISALLADPTRRFIYVEIAFFSRWWHQQTNATQEVVRDLVRQGRLEFANGGWVMNDEAATHYGAIVDQMTLGLRFLEDTFGNDGRPRVAWHIDPFGHSREQASLFAQMGFDGFFFGRLDYQDKWVRMQKLEMEQVWRASTSLKPPTADLFTGVLPNGYNPPRNLCWDVLCVDQPLVEDPRSPEYNAKELVDYFLNVATAQGRYYRTNHTVMTMGSDF... | learning or memory mannose metabolic process oligosaccharide catabolic process protein deglycosylation protein modification process azurophil granule lumen; extracellular exosome; extracellular region; extracellular space; intracellular membrane-bounded organelle; lysosomal lumen; lysosome; nucleoplasm alpha-mannosidas... |
fructose 1,6-bisphosphate metabolic process fructose 6-phosphate metabolic process fructose metabolic process gluconeogenesis sucrose biosynthetic process | anchoring junction; cytoplasm; cytosol; extracellular exosome; nucleus; plasma membrane; Z disc | fructose 1,6-bisphosphate 1-phosphatase activity identical protein binding metal ion binding | Homo sapiens | 3D-structure Allosteric enzyme Calcium Carbohydrate metabolism Cell junction Cytoplasm Disease variant Gluconeogenesis Hydrolase Leukodystrophy Magnesium Metal-binding Nucleus Phosphoprotein Reference proteome | MTDRSPFETD | MTDRSPFETDMLTLTRYVMEKGRQAKGTGELTQLLNSMLTAIKAISSAVRKAGLAHLYGIAGSVNVTGDEVKKLDVLSNSLVINMVQSSYSTCVLVSEENKDAIITAKEKRGKYVVCFDPLDGSSNIDCLASIGTIFAIYRKTSEDEPSEKDALQCGRNIVAAGYALYGSATLVALSTGQGVDLFMLDPALGEFVLVEKDVKIKKKGKIYSLNEGYAKYFDAATTEYVQKKKFPEDGSAPYGARYVGSMVADVHRTLVYGGIFLYPANQKSPKGKLRLLYECNPVAYIIEQAGGLATTGTQPVLDVKPEAIHQRVPLILG... | fructose 1,6-bisphosphate metabolic process fructose 6-phosphate metabolic process fructose metabolic process gluconeogenesis sucrose biosynthetic process anchoring junction; cytoplasm; cytosol; extracellular exosome; nucleus; plasma membrane; Z disc fructose 1,6-bisphosphate 1-phosphatase activity identical protein bi... |
anaphase-promoting complex-dependent catabolic process cell division exit from mitosis free ubiquitin chain polymerization positive regulation of exit from mitosis positive regulation of mitotic metaphase/anaphase transition positive regulation of ubiquitin protein ligase activity protein K11-linked ubiquitination prot... | anaphase-promoting complex; cytosol; nucleoplasm; nucleus; plasma membrane; ubiquitin ligase complex | ATP binding ubiquitin conjugating enzyme activity ubiquitin protein ligase activity ubiquitin-like protein ligase binding ubiquitin-protein transferase activity | Homo sapiens | 3D-structure Acetylation Alternative splicing ATP-binding Cell cycle Cell division Mitosis Nucleotide-binding Phosphoprotein Reference proteome Transferase Ubl conjugation Ubl conjugation pathway | MASQNRDPAA | MASQNRDPAATSVAAARKGAEPSGGAARGPVGKRLQQELMTLMMSGDKGISAFPESDNLFKWVGTIHGAAGTVYEDLRYKLSLEFPSGYPYNAPTVKFLTPCYHPNVDTQGNICLDILKEKWSALYDVRTILLSIQSLLGEPNIDSPLNTHAAELWKNPTAFKKYLQETYSKQVTSQEP | anaphase-promoting complex-dependent catabolic process cell division exit from mitosis free ubiquitin chain polymerization positive regulation of exit from mitosis positive regulation of mitotic metaphase/anaphase transition positive regulation of ubiquitin protein ligase activity protein K11-linked ubiquitination prot... |
phosphorylation pyridoxal 5'-phosphate salvage pyridoxal metabolic process pyridoxamine metabolic process | cytosol; extracellular exosome; extracellular region; nucleoplasm; nucleus; secretory granule lumen; specific granule lumen | ATP binding lithium ion binding magnesium ion binding potassium ion binding protein homodimerization activity pyridoxal kinase activity pyridoxal phosphate binding sodium ion binding zinc ion binding | Homo sapiens | 3D-structure Acetylation Alternative splicing ATP-binding Charcot-Marie-Tooth disease Cobalt Cytoplasm Disease variant Kinase Magnesium Manganese Metal-binding Neurodegeneration Neuropathy Nucleotide-binding Phosphoprotein Reference proteome Sodium Transferase Zinc | MEEECRVLSI | MEEECRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSDELQELYEGLRLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQSKRDIEDPEIVVQATVL | phosphorylation pyridoxal 5'-phosphate salvage pyridoxal metabolic process pyridoxamine metabolic process cytosol; extracellular exosome; extracellular region; nucleoplasm; nucleus; secretory granule lumen; specific granule lumen ATP binding lithium ion binding magnesium ion binding potassium ion binding protein homodi... |
monounsaturated fatty acid biosynthetic process positive regulation of cold-induced thermogenesis response to fatty acid unsaturated fatty acid biosynthetic process | endoplasmic reticulum; endoplasmic reticulum membrane; membrane; nucleolus | iron ion binding oxidoreductase activity palmitoyl-CoA 9-desaturase activity stearoyl-CoA 9-desaturase activity | Homo sapiens | 3D-structure Direct protein sequencing Endoplasmic reticulum Fatty acid biosynthesis Fatty acid metabolism Iron Lipid biosynthesis Lipid metabolism Membrane Metal-binding Oxidoreductase Phosphoprotein Reference proteome Transmembrane Transmembrane helix | MPAHLLQDDI | MPAHLLQDDISSSYTTTTTITAPPSRVLQNGGDKLETMPLYLEDDIRPDIKDDIYDPTYKDKEGPSPKVEYVWRNIILMSLLHLGALYGITLIPTCKFYTWLWGVFYYFVSALGITAGAHRLWSHRSYKARLPLRLFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGSTLDLSDLEAEKLVMFQRRYYKPGLLMMCFILPTLVPWYFWGETFQNSVFVATFLRYAVVLNATWLVNSAAHLFGYRPYDKNISPRENILVSLGAVGEGFHNYHHSFPYDYSASEYRWHINFT... | monounsaturated fatty acid biosynthetic process positive regulation of cold-induced thermogenesis response to fatty acid unsaturated fatty acid biosynthetic process endoplasmic reticulum; endoplasmic reticulum membrane; membrane; nucleolus iron ion binding oxidoreductase activity palmitoyl-CoA 9-desaturase activity ste... |
DNA damage response nucleotide-excision repair transcription by RNA polymerase II transcription initiation at RNA polymerase II promoter UV protection | nucleotide-excision repair factor 3 complex; transcription factor TFIIH holo complex; transcription preinitiation complex | 3'-5' DNA helicase activity ATP binding ATP hydrolysis activity DNA binding | Dictyostelium discoideum | ATP-binding DNA damage DNA repair DNA-binding Helicase Hydrolase Nucleotide-binding Nucleus Reference proteome Transcription Transcription regulation | MSSGDSNLKR | MSSGDSNLKRRRGGNTGQSSKSYNTWTDYEEDLEESGEFNQSIKKTTNTSSATLTSSEEKGSLLDYSKRCILKQDNKSRPIWVCPDGHIFLETFSAIYKQASDFLVAIAEPVCRPQNIHEYQLTPYSLYAAVSVGLETNDIITVLGRLSKLALPKEVEQFVRQCTQSYGKVKLVLQKNKYFVESAYPEVLEFLLKDSSIATARIKPTLEESVVDPKTGFIINKEVVTGAQISGGLQANQSLDPVLKNDALSNLLEEEEEDTVNNSDQHFHSFEIDPQQVEEVKKRCIQLDYPVLEEYDFRNDTVNPNLNIDLKPTTMIRP... | DNA damage response nucleotide-excision repair transcription by RNA polymerase II transcription initiation at RNA polymerase II promoter UV protection nucleotide-excision repair factor 3 complex; transcription factor TFIIH holo complex; transcription preinitiation complex 3'-5' DNA helicase activity ATP binding ATP hyd... |
cell differentiation culmination involved in sorocarp development positive regulation of gene expression receptor signaling pathway via STAT sporulation resulting in formation of a cellular spore | nucleoplasm; nucleus | sequence-specific DNA binding | Dictyostelium discoideum | Developmental protein Differentiation DNA-binding Nucleus Reference proteome Sporulation Transcription Transcription regulation | MNQSQNFHNI | MNQSQNFHNIDLGHYGAQGSNQSFNNNNNGNNGMMMNQQQMQQHVVPHLHHLQQQQQQPQQQQLRNVPDYSNSPNGTTNGSTMSPNCINTNNNNNNNNNNNNNSNNNNNNNNNASNNLTSNKSSSTNTPQIGQLQASPANLTNSPSAISSPITISNNSSLNSPSTTSSPNLLLNGTSNKRIMISQQTCLVEEKFSKNGVQKNVHVVVKNNPFLLTLSLLDSSLNFHQLTPEVQLVYDSESLKEVDSATVKPLEYKTRANEEGDQLTIELRIKVLSSQLEDMLFRAKVKIVDPRTRKETHGLSVITHPIRVVSKPDQVKKK... | cell differentiation culmination involved in sorocarp development positive regulation of gene expression receptor signaling pathway via STAT sporulation resulting in formation of a cellular spore nucleoplasm; nucleus sequence-specific DNA binding Dictyostelium discoideum Developmental protein Differentiation DNA-bindin... |
chemotaxis to cAMP detection of mechanical stimulus hyperosmotic response mitotic actomyosin contractile ring assembly actin filament organization mitotic cytokinesis negative regulation of actin filament polymerization protein localization to cleavage furrow regulation of actin cytoskeleton organization regulation of ... | cell cortex; cell trailing edge; cleavage furrow; cytosol; filopodium; lamellipodium | actin filament binding calmodulin binding GTPase activator activity identical protein binding small GTPase binding | Dictyostelium discoideum | Cell cycle Cell division Coiled coil Reference proteome | MEGLEIEDED | MEGLEIEDEDVILLDEDDDSSSSSTVNNSSSNIKNNGNTNNNIGNDDSNKVTLMTSLREKGWGSGMLVDKEKNQYGTIKSYKDDKSSPWFEERQVIATLYKARVLLHEMIYTKMNQERLLSGNLCVGEIQSLLNTQKEDVETDWIAEIQELKRNMVAEIRRNHLLERDVNKLDKRIALLIKHRSNIKDLLLEQNKGKKDKKKKGDDKAEYITLDQKQLESYQNLFYLLQTEPHYLAKLVTLIQADQMEDFLDTVFLTLFGDDFSPREEFLILSLFRLAIGQEMSRIKSAGDLLAVESVVPKMIITYTRRKQGHEFLKQII... | chemotaxis to cAMP detection of mechanical stimulus hyperosmotic response mitotic actomyosin contractile ring assembly actin filament organization mitotic cytokinesis negative regulation of actin filament polymerization protein localization to cleavage furrow regulation of actin cytoskeleton organization regulation of ... |
intracellular protein transport mitotic cytokinesis regulation of filopodium assembly vesicle-mediated transport | cytosol; Golgi apparatus; pathogen-containing vacuole; perinuclear region of cytoplasm; phagocytic vesicle; plasma membrane | GTP binding GTPase activity | Dictyostelium discoideum | ER-Golgi transport Golgi apparatus GTP-binding Hydrolase Lipoprotein Myristate Nucleotide-binding Protein transport Reference proteome Transport | MGLAFGKLFS | MGLAFGKLFSRFFGKKDMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEFKNINFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIQEACDELTKMLNEDELRDAVLLVFCNKQDLPNAMSVAEVTDKLNLHSLRSRKWYIQSTCATSGDGLYEGLDWLSNTLTSSSK | intracellular protein transport mitotic cytokinesis regulation of filopodium assembly vesicle-mediated transport cytosol; Golgi apparatus; pathogen-containing vacuole; perinuclear region of cytoplasm; phagocytic vesicle; plasma membrane GTP binding GTPase activity Dictyostelium discoideum ER-Golgi transport Golgi appar... |
culmination involved in sorocarp development defense response negative regulation of DNA-templated transcription positive regulation of gene expression receptor signaling pathway via JAK-STAT receptor signaling pathway via STAT regulation of cell population proliferation regulation of gene expression regulation of tran... | cytosol; nucleus | DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific identical protein binding RNA polymerase II cis-regulatory region sequence-specific DNA binding | Dictyostelium discoideum | 3D-structure Coiled coil Cytoplasm Direct protein sequencing DNA-binding Nucleus Phosphoprotein Reference proteome Repressor SH2 domain Transcription Transcription regulation | MSSAEFSMDD | MSSAEFSMDDFEDTFDSNATISTKDLFEGSDRLPLNQSINTTIQNLYLPNGGFAIGDQSQQQYYQAMPPLNQSDQFNLGRSNNLTPRTNQLQQLQQQQQQQQQPQQQQQQQTYGTQSPIHMSQTPSSPLSSPLPSPTPFSRQQSYNNNNSNNTSSSQNYNNNNININNNNNNNNTNNNNNNNNGNNSNGNNGNNNNNNNNNNNNNTNNNNNNNQQQQQQQQQQQQQQQQQQQQQQQGNPNLSSPQPILDTIYKLLSEQEQTLVQMIHEQSLLLNRLPPTLDENSLAPLKSLSQKQITLSGQMNTEMSALDATKKGMILEP... | culmination involved in sorocarp development defense response negative regulation of DNA-templated transcription positive regulation of gene expression receptor signaling pathway via JAK-STAT receptor signaling pathway via STAT regulation of cell population proliferation regulation of gene expression regulation of tran... |
axon guidance border follicle cell migration cell fate commitment dsRNA transport follicle cell of egg chamber development follicle cell of egg chamber-cell adhesion germ cell development germarium-derived egg chamber formation glycosphingolipid biosynthetic process insect visual primordium formation maintenance of pol... | cytoplasm; membrane | beta-1,4-mannosyltransferase activity | Drosophila melanogaster | Developmental protein Glycosyltransferase Membrane Reference proteome Transferase Transmembrane Transmembrane helix | MNSTTKHLLH | MNSTTKHLLHCTLLITVIVTFEVFSGGIKIDENSFTLVDPWTEYGQLATVLLYLLRFLTLLTLPQVLFNFCGLVFYNAFPEKVVLKGSPLLAPFICIRVVTRGDFPDLVKTNVLRNMNTCLDTGLENFLIEVVTDKAVNLSQHRRIREIVVPKEYKTRTGALFKSRALQYCLEDNVNVLNDSDWIVHLDEETLLTENSVRGIINFVLDGKHPFGQGLITYANENVVNWLTTLADSFRVSDDMGKLRLQFKLFHKPLFSWKGSYVVTQVSAERSVSFDNGIDGSVAEDCFFAMRAFSQGYTFNFIEGEMYEKSPFTLLDFL... | axon guidance border follicle cell migration cell fate commitment dsRNA transport follicle cell of egg chamber development follicle cell of egg chamber-cell adhesion germ cell development germarium-derived egg chamber formation glycosphingolipid biosynthetic process insect visual primordium formation maintenance of pol... |
apposition of dorsal and ventral imaginal disc-derived wing surfaces axon ensheathment cell adhesion cell differentiation cell migration germ-line stem cell population maintenance glial cell migration mesoderm development mesodermal cell migration muscle attachment muscle cell fate determination muscle organ developmen... | cytoplasm; nucleus | mRNA 3'-UTR binding mRNA binding | Drosophila melanogaster | Alternative splicing Developmental protein Nucleus Reference proteome RNA-binding | MSVCESKAVV | MSVCESKAVVQQQLQQHLQQQAAAAVVAVAQQQQAQAQAQAQAQAQQQQQAPQVVVPMTPQHLTPQQQQQSTQSIADYLAQLLKDRKQLAAFPNVFTHVERLLDEEIARVRASLFQINGVKKEPLTLPEPEGSVVTMNEKVYVPVREHPDFNFVGRILGPRGMTAKQLEQETGCKIMVRGKGSMRDKKKEDANRGKPNWEHLSDDLHVLITVEDTENRATVKLAQAVAEVQKLLVPQAEGEDELKKRQLMELAIINGTYRDTTAKSVAVCDEEWRRLVAASDSRLLTSTGLPGLAAQIRAPAAAPLGAPLILNPRMTVPT... | apposition of dorsal and ventral imaginal disc-derived wing surfaces axon ensheathment cell adhesion cell differentiation cell migration germ-line stem cell population maintenance glial cell migration mesoderm development mesodermal cell migration muscle attachment muscle cell fate determination muscle organ developmen... |
apoptotic process negative regulation of peptidoglycan recognition protein signaling pathway negative regulation of Toll signaling pathway neuron remodeling nurse cell apoptotic process positive regulation of compound eye retinal cell programmed cell death programmed cell death programmed cell death involved in cell de... | cytoplasm; nucleus; plasma membrane | BIR domain binding cysteine-type endopeptidase activity cysteine-type endopeptidase activity involved in apoptotic process cysteine-type endopeptidase activity involved in execution phase of apoptosis ubiquitin protein ligase binding | Drosophila melanogaster | 3D-structure Apoptosis Hydrolase Protease Reference proteome Thiol protease Zymogen | MDATNNGESA | MDATNNGESADQVGIRVGNPEQPNDHTDALGSVGSGGAGSSGLVAGSSHPYGSGAIGQLANGYSSPSSSYRKNVAKMVTDRHAAEYNMRHKNRGMALIFNHEHFEVPTLKSRAGTNVDCENLTRVLKQLDFEVTVYKDCRYKDILRTIEYAASQNHSDSDCILVAILSHGEMGYIYAKDTQYKLDNIWSFFTANHCPSLAGKPKLFFIQACQGDRLDGGVTMQRSQTETDGDSSMSYKIPVHADFLIAYSTVPGFYSWRNTTRGSWFMQSLCAELAANGKRLDILTLLTFVCQRVAVDFESCTPDTPEMHQQKQIPCITT... | apoptotic process negative regulation of peptidoglycan recognition protein signaling pathway negative regulation of Toll signaling pathway neuron remodeling nurse cell apoptotic process positive regulation of compound eye retinal cell programmed cell death programmed cell death programmed cell death involved in cell de... |
memory peptide metabolic process regulation of imaginal disc-derived wing size response to fungus sexual reproduction | extracellular region; extracellular space; membrane | copper ion binding peptidylglycine monooxygenase activity | Drosophila melanogaster | Copper Disulfide bond Glycoprotein Metal-binding Monooxygenase Oxidoreductase Reference proteome Secreted Signal | MPRISEIAAS | MPRISEIAASVGLLLLIGVISVDGLVKEGDYQNSLYQQNLESNSATGATASFPFLMPNVSPQTPDLYLCTPIKVDPTTTYYIVGFNPNATMNTAHHMLLYGCGEPGTSKTTWNCGEMNRASQEESASPCGPHSNSQIVYAWARDAQKLNLPEGVGFKVGKNSPIKYLVLQVHYAHIDKFKDGSTDDSGVFLDYTEEPRKKLAGTLLLGTDGQIPAMKTEHLETACEVNEQKVLHPFAYRVHTHGLGKVVSGYRVRTNSDGEQEWLQLGKRDPLTPQMFYNTSNTDPIIEGDKIAVRCTMQSTRHRTTKIGPTNEDEMCNF... | memory peptide metabolic process regulation of imaginal disc-derived wing size response to fungus sexual reproduction extracellular region; extracellular space; membrane copper ion binding peptidylglycine monooxygenase activity Drosophila melanogaster Copper Disulfide bond Glycoprotein Metal-binding Monooxygenase Oxido... |
chromosome condensation chromosome segregation establishment of protein localization meiotic spindle midzone assembly mitotic cell cycle mitotic cytokinesis mitotic spindle midzone assembly mitotic spindle organization phosphorylation positive regulation of mitotic cell cycle spindle assembly checkpoint positive regula... | chromosome passenger complex; condensed chromosome; condensed nuclear chromosome; cytoplasm; kinetochore; microtubule cytoskeleton; midbody; spindle; spindle microtubule; spindle midzone; spindle pole centrosome | ATP binding ATPase binding histone H3 kinase activity kinesin binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity | Caenorhabditis elegans | ATP-binding Cell cycle Cell division Chromatin regulator Chromosome Chromosome partition Cytoplasm Cytoskeleton Developmental protein Kinase Meiosis Mitosis Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MENKPPVINL | MENKPPVINLPEKETVNTPQKGGKFTINDFEIGRPLGKGKFGSVYLARTKTGHFHVAIKVLFKSQLISGGVEHQLEREIEIQSHLNHPNIIKLYTYFWDAKKIYLVLEYAPGGEMYKQLTVSKRFSEPTAAKYMYEIADALSYCHRKNVIHRDIKPENLLIGSQGELKIGDFGWSVHAPSNKRQTMCGTMDYLPPEMVNGADHSDAVDLWAIGVLCYEFLVGKPPFEHEDQSKTYAAIKAARFTYPDSVKKGARDLIGRLLVVDPKARCTLEQVKEHYWIQGMMEAKIRAEKQQKIEKEASLRNH | chromosome condensation chromosome segregation establishment of protein localization meiotic spindle midzone assembly mitotic cell cycle mitotic cytokinesis mitotic spindle midzone assembly mitotic spindle organization phosphorylation positive regulation of mitotic cell cycle spindle assembly checkpoint positive regula... |
actin filament organization embryo development ending in birth or egg hatching locomotion muscle thin filament assembly myofibril assembly negative regulation of actin filament depolymerization nematode larval development pointed-end actin filament capping sarcomere organization | cytoplasm; cytoskeleton; myofibril; striated muscle thin filament; terminal web | actin filament binding tropomyosin binding | Caenorhabditis elegans | 3D-structure Actin-binding Alternative splicing Cytoplasm Cytoskeleton Reference proteome | MSQAKTDYYS | MSQAKTDYYSEEKTFSAPSANSQQGTQLPSKVYNKGLKDLEDNDIEGLLSSLSIDELEDLNNDFDPDNSMLPPSQRCRDQTDKEPTGPYKRDNLLKFLEDKAKTEKDWEDVCPYTPGQKRGKVYDSDSGRNSEEPENGKMEMPIEIDLDDDEEELECALVTAPEKDLVDLAGILGMHNVLNQPQYYNALKGKTQDESTGTTFNGIMQSYVPRIVPDEPDNDTDVESCINRLREDDTDLKEVNINNMKRVSKERIRSLIEAACNSKHIEKFSLANTAISDSEARGLIELIETSPSLRVLNVESNFLTPELLARLLRSTLVT... | actin filament organization embryo development ending in birth or egg hatching locomotion muscle thin filament assembly myofibril assembly negative regulation of actin filament depolymerization nematode larval development pointed-end actin filament capping sarcomere organization cytoplasm; cytoskeleton; myofibril; stri... |
endosome to lysosome transport ephrin receptor signaling pathway negative regulation of MAPK cascade protein localization to non-motile cilium protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway response to hermaphrodite contact | cilium; early endosome; endosome; ESCRT-0 complex | phosphatidylinositol binding ubiquitin binding | Caenorhabditis elegans | Alternative splicing Cell projection Cilium Developmental protein Endosome Protein transport Reference proteome SH3 domain Transport | MKKQKSFPMS | MKKQKSFPMSAYEDLLGKITAPTITVENWEGILAFCDMINNDFEGSKTGIKSLRKRLNNRDPHVVLLAISVLDSCWANCEERFRKEVSSAQFINELKALCTSSQRQVAEKMRLTVQKWVDTECKTEQSLSLIVTLHKNLVADGYSFVVDDPKSKTKAIDAKFANDPNYVGSAQEEEAIAKAIAASLADAEKQEKAKKSTSTMYPSAKASSPAVQTNSNIPEKNVRALYDFEAAESNELSFVAGDIITITDESNPHWWTGRIGTQQGLFPSSFVTNQLDDLKSKETDSSQKAPEVVASINEAILVRCLQVLHECDPTGERQ... | endosome to lysosome transport ephrin receptor signaling pathway negative regulation of MAPK cascade protein localization to non-motile cilium protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway response to hermaphrodite contact cilium; earl... |
cell division DNA endoreduplication embryo development ending in birth or egg hatching G1/S transition of mitotic cell cycle germ cell development germline cell cycle switching, mitotic to meiotic cell cycle gonad development meiotic cell cycle positive regulation of cell population proliferation positive regulation of... | centriole; centrosome; chromatin; cyclin E1-CDK2 complex; cyclin-dependent protein kinase holoenzyme complex; cytoplasm; nucleus | cyclin-dependent protein serine/threonine kinase regulator activity | Caenorhabditis elegans | Alternative splicing Cell cycle Cell division Cyclin Cytoplasm Cytoskeleton Meiosis Mitosis Nucleus Reference proteome | MAGRKSSRTA | MAGRKSSRTAERVPTTQKPERKSAILSPHDELRERLLETAIDMKENIPQRNTRNSSVGSQKSDCSETRKRRSTKEGPAAKRHSGEKHRNGSREDSLEYISEYSDDREVGSSSSQSSRTRGQPLPAMPEEEEVFDKSSSSDNLAESEESHEMVRLEERQDIEEEIEDDFDDEEEDVVNDKEEYEEIESEDEDDYPVQNEGFAVTKRLMNDEHMVTAPTFLSTAKCDGIGSPTKVWSLMVKRDEIPRATRFLLGNHPDMDDEKRRILIDWMMEVCESEKLHRETFHLAVDYVDRYLESSNVECSTDNFQLVGTAALFIAAKY... | cell division DNA endoreduplication embryo development ending in birth or egg hatching G1/S transition of mitotic cell cycle germ cell development germline cell cycle switching, mitotic to meiotic cell cycle gonad development meiotic cell cycle positive regulation of cell population proliferation positive regulation of... |
negative regulation of DNA-templated transcription response to ethanol response to heat response to osmotic stress response to oxidative stress | nucleolus; nucleus | 2-oxoglutarate-dependent dioxygenase activity histone H3K36 demethylase activity histone H3K36me/H3K36me2 demethylase activity histone H3K4 demethylase activity histone H3K4me/H3K4me2/H3K4me3 demethylase activity iron ion binding | Caenorhabditis elegans | Alternative splicing Chromatin regulator Dioxygenase Iron Metal-binding Nucleus Oxidoreductase Reference proteome Repressor Transcription Transcription regulation | MGKKKNSNKS | MGKKKNSNKSAAAAPAVKHNDRWSSIELGEAKSAAVSHYKEPSKEPKFVHPAKLEKVKRIHDGLNIDRVLSHGPVPKQNGGTKRKHVEVTTQKLENKKPKVEVKKEDEKSKNKKMKNQNKHTALVQNETSTRSTYFVEEPDNENKVTLISNGREIAFKKTEVVESDDEQMIGLDSDEELEDEDETDIDEDEMMIDPKDIERYINFESVEDEEDMEDEEIEDEEFEDEEFEDEEEEADEQEEEEEDVSDEESVVSEMDADSDDEGFIAGKDREAHVISKDKFTRNAPAVDFDKFPFTDEDSVVTSSRAFGFMISPCDVQTF... | negative regulation of DNA-templated transcription response to ethanol response to heat response to osmotic stress response to oxidative stress nucleolus; nucleus 2-oxoglutarate-dependent dioxygenase activity histone H3K36 demethylase activity histone H3K36me/H3K36me2 demethylase activity histone H3K4 demethylase activ... |
cellular response to light stimulus entrainment of circadian clock by photoperiod G protein-coupled receptor signaling pathway negative regulation of transcription by RNA polymerase II phototransduction sensory perception of sound thermotaxis visual perception | membrane; rhabdomere | G protein-coupled photoreceptor activity | Drosophila melanogaster | Alternative splicing Chromophore Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Photoreceptor protein Receptor Reference proteome Retinal protein Sensory transduction Transducer Transmembrane Transmembrane helix Vision | MASLHPPSFA | MASLHPPSFAYMRDGRNLSLAESVPAEIMHMVDPYWYQWPPLEPMWFGIIGFVIAILGTMSLAGNFIVMYIFTSSKGLRTPSNMFVVNLAFSDFMMMFTMFPPVVLNGFYGTWIMGPFLCELYGMFGSLFGCVSIWSMTLIAYDRYCVIVKGMARKPLTATAAVLRLMVVWTICGAWALMPLFGWNRYVPEGNMTACGTDYFAKDWWNRSYIIVYSLWVYLTPLLTIIFSYWHIMKAVAAHEKAMREQAKKMNVASLRNSEADKSKAIEIKLAKVALTTISLWFFAWTPYTIINYAGIFESMHLSPLSTICGSVFAKANA... | cellular response to light stimulus entrainment of circadian clock by photoperiod G protein-coupled receptor signaling pathway negative regulation of transcription by RNA polymerase II phototransduction sensory perception of sound thermotaxis visual perception membrane; rhabdomere G protein-coupled photoreceptor activi... |
DNA repair DNA replication nematode pharynx development nucleosome assembly nucleosome disassembly pharynx development positive regulation of cell cycle regulation of chromatin organization regulation of embryonic development | FACT complex; nucleus | DNA binding histone binding nucleosome binding | Caenorhabditis elegans | Chromosome DNA damage DNA repair DNA replication DNA-binding Nucleus Reference proteome Transcription Transcription regulation | MTELKFKGVY | MTELKFKGVYVEDIGHLTCGTLTLTENSINFIGDKGGKSVYITGTDVDKLKWQKLGNKPGLRVGLSDGGAHRFGGFLDDDLQKIQSFTSSNWSKSINQSNLFINGWNYGQADVKGKNIEFSWENEPIFEIPCTNVSNVIANKNEAILEFHQNEQSKVQLMEMRFHMPVDLENEEDTDKVEEFKKAVLAYAGLEAETEQPICLLTDILCTTPRGRYDIKVYPTSIALHGKTYDYKIPVKTINRLFLVPHKDGRQVYFVLSLNPPIRQGQTHYSYLIFEFGKDEEEDLELSLTDEQLDYFNGNLQREMTGPIYETISILFKS... | DNA repair DNA replication nematode pharynx development nucleosome assembly nucleosome disassembly pharynx development positive regulation of cell cycle regulation of chromatin organization regulation of embryonic development FACT complex; nucleus DNA binding histone binding nucleosome binding Caenorhabditis elegansChr... |
axon extension involved in regeneration axon regeneration formation of growth cone in injured axon MAPK cascade microtubule polymerization p38MAPK cascade phosphorylation positive regulation of axon extension positive regulation of axon extension involved in regeneration regulation of 3'-UTR-mediated mRNA stabilization... | axon; cilium; cytoplasm; dendrite; neuronal cell body; synapse | ATP binding MAP kinase kinase kinase activity metal ion binding protein kinase activity protein serine kinase activity ubiquitin protein ligase binding | Caenorhabditis elegans | Alternative splicing ATP-binding Cell projection Cytoplasm Kinase Magnesium Metal-binding Neurogenesis Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Synapse Transferase Ubl conjugation | MTSTTMVTTL | MTSTTMVTTLDLVTPTSEEQPGPAPESSDFSTVVLSPDGSELVTQSAPNTPIQHREQANAEFGQKEGSPDPKNMVAATGNASKPSLNSFYADGLGQLRNGLFSCFQPVFGYFGTKTTVEIEKSEDELWEIPFDAISELEWLGSGSQGAVFRGQLENRTVAVKKVNQLKETEIKHLRHLRHQNIIEFLGVCSKSPCYCIVMEYCSKGQLCTVLKSRNTITRELFAQWVKEIADGMHYLHQNKVIHRDLKSPNILISAEDSIKICDFGTSHMQKKMDSTMMSFCGTVSWMAPEMIKKQPCNEKVDVYSFGVVLWEMLTRETP... | axon extension involved in regeneration axon regeneration formation of growth cone in injured axon MAPK cascade microtubule polymerization p38MAPK cascade phosphorylation positive regulation of axon extension positive regulation of axon extension involved in regeneration regulation of 3'-UTR-mediated mRNA stabilization... |
heparan sulfate proteoglycan biosynthetic process pharynx development protein glycosylation | endoplasmic reticulum; Golgi apparatus; protein-containing complex | enzyme binding glycosyltransferase activity | Caenorhabditis elegans | Endoplasmic reticulum Glycoprotein Golgi apparatus Reference proteome Signal | MQNVMKFHLV | MQNVMKFHLVIFMLFGSVRLQNPTIERKQCTMSNCFDFSKCSTSKKVYIHPMEKRFEESPQSVIYSKILKHFLESNHYTNDPNEACIFLLGIDTTDRDVRSQNYVKNVNDYIESLDPSVWNNGRNHLIFNFYHGTFPDYDDHNLNFDTGEAMIARASSSENNFIKVFDVSLPLFHENHPYEIKESKSERNDDRIENQRKYLVSFKGKRYVYGIGSGTRNLVHHLHNGDDIVMVTTCKHNNDWQVYQDDRCQRDNDEYDRWEYDELLANSTFCLVPRGRRLGSFRFLETLRSGCVPVVISDSWILPFSETIDWNSAAIVVA... | heparan sulfate proteoglycan biosynthetic process pharynx development protein glycosylation endoplasmic reticulum; Golgi apparatus; protein-containing complex enzyme binding glycosyltransferase activity Caenorhabditis elegansEndoplasmic reticulum Glycoprotein Golgi apparatus Reference proteome Signal MQNVMKFHLV MQNVMKF... |
embryonic morphogenesis heparan sulfate proteoglycan biosynthetic process pharynx development protein glycosylation | endoplasmic reticulum membrane; Golgi apparatus; Golgi membrane; protein-containing complex | acetylglucosaminyltransferase activity enzyme binding glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity glycosyltransferase activity heparan sulfate N-acetylglucosaminyltransferase activity ... | Caenorhabditis elegans | Disulfide bond Endoplasmic reticulum Glycoprotein Glycosyltransferase Golgi apparatus Manganese Membrane Metal-binding Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix | MAIKLNGSSR | MAIKLNGSSRSFVPSLRVSAFLIFIFFVITYIIIYNVSFSEPSWITQDALKQNIENLDDYDASCSGYSIGRILREQKRILASVRLELTESQVKIEEIRTVQEELQRLIPQKQLELSALEGEIEAAQRQLEELRETQNVKVFLPFSPLQIPRELEQPSQISPNQLDDIIDYSRCSISSFMPVYVDIITSGQSEKEWLNVFQEVIPNLVETPDKACIKIHISNGIASPNTTFNSILFNVGSPIINFQSKSIHVQASKIRSFDFPVDVNHIAVEKVDLTPLLPFQRENLISLIVDNTELNFSAFSSLSAEPSRRPIVIVKCSQ... | embryonic morphogenesis heparan sulfate proteoglycan biosynthetic process pharynx development protein glycosylation endoplasmic reticulum membrane; Golgi apparatus; Golgi membrane; protein-containing complex acetylglucosaminyltransferase activity enzyme binding glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-a... |
D-amino acid catabolic process | cytoplasm; extracellular region | D-amino-acid oxidase activity D-aspartate oxidase activity FAD binding | Caenorhabditis elegans | FAD Flavoprotein Glycoprotein Oxidoreductase Reference proteome Secreted Signal | MLYALLLLFG | MLYALLLLFGGVSTVSSLRVAVVGEGVIGLSTATAILDLAEKRNIPAPEIHIFHHKPFEKILSRHIAGLFRIDSGSEIDRKYGYDTFEKLATLWREYGGLSGVQLVSGHILSDSKTKLDSQRESYGSLVYNYRDLAEPELFGPTSLFDLPRNTTTRGIHYTAYTSEGLRFCPFLKKELMTKGVRFTQRRIGNLEELGAEFDVVVNSAGLLGGVLAGDDAGNMKPIRGVLIRVDAPWQKHFLYRDFSTITIPVIDHVYMGTVKQEGAFGPNNVTSADIQDITSRYVALQPSFKRVHMLSSFVGYRPGRKQVRVEKQIRETN... | D-amino acid catabolic process cytoplasm; extracellular region D-amino-acid oxidase activity D-aspartate oxidase activity FAD binding Caenorhabditis elegansFAD Flavoprotein Glycoprotein Oxidoreductase Reference proteome Secreted Signal MLYALLLLFG MLYALLLLFGGVSTVSSLRVAVVGEGVIGLSTATAILDLAEKRNIPAPEIHIFHHKPFEKILSRHIAGLFRID... |
cortical actin cytoskeleton organization dephosphorylation eggshell formation motor neuron axon guidance oocyte maturation polar body extrusion after meiotic divisions positive regulation of protein localization to cell cortex | cell cortex; nucleus | protein kinase binding protein kinase inhibitor activity protein tyrosine phosphatase activity | Caenorhabditis elegans | Cytoplasm Developmental protein Reference proteome | MALNSEVMFR | MALNSEVMFREQINAMRSQAGRKRATSLQSFCSGNTDDSSADSTDNMDMMVDYPQQKGVSCMRARFNSESTLSKSFRKKVKKLAQKDRRSKERLNGNSEEDAIEVPRGAPSTYAAPSKLRKSKALDCLVSEKPKDEGRREDSGHGADIEMAKGHFNNVRMKVFAARTAMQVEPALVMKTRKALEMKNAVLENHQSPGAFSLHAAYKIAASAESRVGSITPCNKKVTKEAMANLIRSSYDDTEITQELLFSSKFDTKWKGRYTDIYMRRDENGKKPKRPVNGQGWVMPLKSICEKFGINSTFFTNHRIDLKSARDQVLLMR... | cortical actin cytoskeleton organization dephosphorylation eggshell formation motor neuron axon guidance oocyte maturation polar body extrusion after meiotic divisions positive regulation of protein localization to cell cortex cell cortex; nucleus protein kinase binding protein kinase inhibitor activity protein tyrosin... |
molting cycle phosphorylation positive regulation of endocytosis | cytoplasm | ATP binding metal ion binding protein serine kinase activity protein serine/threonine kinase activity | Caenorhabditis elegans | ATP-binding Cytoplasm Developmental protein Kinase Magnesium Metal-binding Nucleotide-binding Reference proteome Serine/threonine-protein kinase Transferase | MDNYEKVRVV | MDNYEKVRVVGRGAFGVCWLCRGKNDASHQKVIIKLINTHGMTEKEENSIQSEVNLLKKVQHPLIIGYIDSFIMDNQLGIVMQYAEGGTLERLINDQRAIKDSNMREYFPEKTVLDYFTQILIALNHMHQKNIVHRDLKPQNILMNRRKTVLKLSDFGISKELGTKSAASTVIGTPNYLSPEICESRPYNQKSDMWSLGCVLYELLQLERAFDGENLPAIVMKITRSKQNPLGDHVSNDVKMLVENLLKTHTDKRPDVSQLLSDPLVLPYLISIHCDLGRIEPPPTDKRKPSASLSSRLRTYPTQSTLRPYSLSSNAPTT... | molting cycle phosphorylation positive regulation of endocytosis cytoplasm ATP binding metal ion binding protein serine kinase activity protein serine/threonine kinase activity Caenorhabditis elegansATP-binding Cytoplasm Developmental protein Kinase Magnesium Metal-binding Nucleotide-binding Reference proteome Serine/t... |
cell differentiation innate immune response phosphorylation spermatid development transmembrane receptor protein tyrosine kinase signaling pathway | cytoplasm; extrinsic component of cytoplasmic side of plasma membrane; plasma membrane | ATP binding non-membrane spanning protein tyrosine kinase activity signaling receptor binding | Caenorhabditis elegans | ATP-binding Cell membrane Cytoplasm Differentiation Kinase Membrane Nucleotide-binding Reference proteome SH2 domain Spermatogenesis Transferase Tyrosine-protein kinase | MRSKSSEGDL | MRSKSSEGDLQPEDTQSREDKETTATYSEDTKPETQKERNAALDNLAKTPIQLVVQPTPLTPAITPCEAPPPPPPPKPSSDNNNSKRLKVKDQLIEVPSDEVGRVENNIDNFPFYHGFMGRNECEAMLSNHGDFLIRMTEIGKRVAYVISIKWKYQNIHVLVKRTKTKKLYWTKKYAFKSICELIAYHKRNHKPIYEGMTLICGLARHGWQLNNEQVTLNKKLGEGQFGEVHKGSLKTSVFAAPVTVAVKTLHQNHLSANEKILFLREANVMLTLSHPNVIKFYGVCTMKEPIMIVMEFCDGKSLEDALLSKEEKVSAED... | cell differentiation innate immune response phosphorylation spermatid development transmembrane receptor protein tyrosine kinase signaling pathway cytoplasm; extrinsic component of cytoplasmic side of plasma membrane; plasma membrane ATP binding non-membrane spanning protein tyrosine kinase activity signaling receptor ... |
cortical granule exocytosis eggshell formation embryo development ending in birth or egg hatching exocytosis membrane addition at site of mitotic cytokinesis mitotic cytokinesis protein transport receptor-mediated endocytosis | apical plasma membrane; centrosome; cortical granule; cytosol; Golgi apparatus; Golgi membrane; Golgi trans cisterna membrane; recycling endosome; recycling endosome membrane; spindle; transport vesicle | GTP binding GTPase activity | Caenorhabditis elegans | Cell membrane Cytoplasm Cytoplasmic vesicle Cytoskeleton Endosome Golgi apparatus GTP-binding Lipoprotein Membrane Nucleotide-binding Prenylation Protein transport Reference proteome Transport | MGSRDDEYDY | MGSRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSISVEGKTVKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHVTYENVERWLKELRDHADQNIVIMLVGNKSDLRHLRAVPTDEAKIYAERNQLSFIETSALDSTNVEAAFTNILTEIYKSVSNKHVGTDRQGYGGGSGTIIPSPASDPPKKQCCIP | cortical granule exocytosis eggshell formation embryo development ending in birth or egg hatching exocytosis membrane addition at site of mitotic cytokinesis mitotic cytokinesis protein transport receptor-mediated endocytosis apical plasma membrane; centrosome; cortical granule; cytosol; Golgi apparatus; Golgi membrane... |
detection of mechanical stimulus involved in sensory perception of touch mechanosensory behavior positive regulation of detection of mechanical stimulus involved in sensory perception of touch positive regulation of mechanosensory behavior potassium ion transport response to mechanical stimulus | axon; plasma membrane | arylesterase activity sodium channel activity | Caenorhabditis elegans | Cell membrane Cell projection Disulfide bond Glycoprotein Hydrolase Ion channel Ion transport Membrane Neurodegeneration Potassium Potassium transport Reference proteome Sodium Sodium channel Sodium transport Transmembrane Transmembrane helix Transport | MGLQSAAAHF | MGLQSAAAHFINRFIIWITIFMVACFLLRLLVVLDLNKRVYNHTPGPCRVLTDNYKGTAGMTYVESQKRVYITLGYGRAHDLKTKTGIAFYKTNRTDGRSQQEMYDLIEMTINWNGYEYKKEFIPTGIDSYSSSNGRVLLYVINAHPNHQCIHFFQIVESSKLNHRKAICDPSFSSLQDIAVVGPDRLFVTNMAAFGRGWAQILEFSLQTGQGAVYYYDGSKLSTAASSLIAPTGIGYDAKRRILYVGSMIRESIFAYKVAKDTTLELLYEMMLLTSPIGVFVESKTGDIWIAAHPVIHESAWHYTHPENQNIHSPSQIL... | detection of mechanical stimulus involved in sensory perception of touch mechanosensory behavior positive regulation of detection of mechanical stimulus involved in sensory perception of touch positive regulation of mechanosensory behavior potassium ion transport response to mechanical stimulus axon; plasma membrane ar... |
endosomal transport positive regulation of gut granule assembly positive regulation of intracellular protein transport | BLOC complex; BLOC-1 complex; cytoplasm; endosome | protein homodimerization activity | Caenorhabditis elegans | Cytoplasm Endosome Reference proteome | MSNTEHNVES | MSNTEHNVESKNVTDTLDEILRLQEDIQARIGSSNHNLETNFESIKDFVSRAHAYIPILNQISKDMIEICERTQALKKKTSQLELSDTNIEDGSTTSTPTTTNKSQ | endosomal transport positive regulation of gut granule assembly positive regulation of intracellular protein transport BLOC complex; BLOC-1 complex; cytoplasm; endosome protein homodimerization activity Caenorhabditis elegansCytoplasm Endosome Reference proteome MSNTEHNVES MSNTEHNVESKNVTDTLDEILRLQEDIQARIGSSNHNLETNFESIK... |
cell differentiation gamete generation | nucleus; P granule | ATP binding ATP hydrolysis activity DEAD/H-box RNA helicase binding JUN kinase binding protein self-association RNA binding RNA helicase activity zinc ion binding | Caenorhabditis elegans | ATP-binding Cytoplasm Helicase Hydrolase Metal-binding Nucleotide-binding Reference proteome Repeat RNA-binding Zinc Zinc-finger | MDKSPTKTSI | MDKSPTKTSIRTKFARHQPISDVDTTEQSSSCIKKDDRGLSSFGVQSSVFSRRSCRMSELEAKPTIISEDQRIAVRSEIGGSFSGFDDKVDNVFHSNNNLHGSPSTTELECPGIMNPRFLVGRSLNSRSRAVTRGSKRTSNVKENEGSIHRSDDQVSTENCSAKDEERDRDSGGVSSYGNKRSDEFCGTSPILEAKGFGISNTCFNCKKYGHRATECSAPQRECANCGDPNHRANECASWSKNGVQEPTKVTYVPVVDKMEEVFSMLKINAGDFFDKFFDASVQLVSRGQPVTIQPCKSFSDSDIPQSMRRNVERAGYTR... | cell differentiation gamete generation nucleus; P granule ATP binding ATP hydrolysis activity DEAD/H-box RNA helicase binding JUN kinase binding protein self-association RNA binding RNA helicase activity zinc ion binding Caenorhabditis elegansATP-binding Cytoplasm Helicase Hydrolase Metal-binding Nucleotide-binding Ref... |
endocytic recycling Golgi organization Golgi vesicle transport lysosomal transport negative regulation of dense core granule transport positive regulation of dense core granule transport positive regulation of locomotion involved in locomotory behavior retrograde transport, endosome to Golgi | cytosol; EARP complex; GARP complex; membrane | syntaxin binding | Caenorhabditis elegans | Coiled coil Golgi apparatus Reference proteome | MSSVLDVTKP | MSSVLDVTKPDFDVEAFVVKLLREKSLDGLVKEEEEMVSAVRRLDSDVHQIVYENYNKFLTATNTVRKIQDEFTQLDSEMKSLSRSMSTISTLIGNLDGVLGEKRDDILQLGSSYKVVNSLKHIFDLPHVLRSEFDERNYGEVLRMFKLAEESLSQYKDVPTVQLVLQKSKKIYDMTENQLMDQLRNPASGAELVSEAVDLLLTIGRDEDEVQKVLLTCSEQSLRVDLKELSANHSDVLDLVDKASESFIPNLTLIATTHDRLFEDKREDLITVLKTEMNSLHALVSKVFLSSSDAKDCSIVVRALDRYFRKISTCRYVI... | endocytic recycling Golgi organization Golgi vesicle transport lysosomal transport negative regulation of dense core granule transport positive regulation of dense core granule transport positive regulation of locomotion involved in locomotory behavior retrograde transport, endosome to Golgi cytosol; EARP complex; GARP... |
proteolysis spermatid development | extracellular space; secretory vesicle | serine-type endopeptidase activity | Caenorhabditis elegans | Cytoplasmic vesicle Differentiation Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Secreted Serine protease Signal Spermatogenesis | MRPRIIVFLF | MRPRIIVFLFQVLVVIKGTKLKYYNDELCGRQSTYTSFMLTDAAGNTGNPTHLAPWAVQIRVKARKGDFEVICGGTLITLKHVLTAAHCFQKHFGAKKEGGEENSMSGRYCESNQRFTDSEILTRTVVTVGAMCTRLEQKYGCVNEKQNGKTLKISRFAIGDFYKTHCEQGNDIVILELESTIDDVEGANYACLPFLPEVNIQSGANVTSFGWGSDPGKGFDNAAFPMIQVLTLATETLATCEENWGTSIPFDSFCTAEEEDKNVCSGDSGGGLTFHQSDSAREFIIAIVSYGSDCVQLIGGSEPRSQINTDVRKHQKFI... | proteolysis spermatid development extracellular space; secretory vesicle serine-type endopeptidase activity Caenorhabditis elegansCytoplasmic vesicle Differentiation Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Secreted Serine protease Signal Spermatogenesis MRPRIIVFLF MRPRIIVFLFQVLVVIKGTKLKYYNDELC... |
lipid modification nematode larval development phosphatidylcholine biosynthetic process phosphatidylethanolamine biosynthetic process phosphatidylserine biosynthetic process positive regulation of growth rate post-embryonic body morphogenesis | endoplasmic reticulum; endoplasmic reticulum membrane; membrane | 1-acylglycerophosphocholine O-acyltransferase activity 1-acylglycerophosphoethanolamine O-acyltransferase activity 1-acylglycerophosphoserine O-acyltransferase activity lysophospholipid acyltransferase activity O-acyltransferase activity | Caenorhabditis elegans | Acyltransferase Alternative splicing Endoplasmic reticulum Lipid biosynthesis Lipid metabolism Membrane Phospholipid biosynthesis Phospholipid metabolism Reference proteome Transferase Transmembrane Transmembrane helix | MGVVGALSEV | MGVVGALSEVTSASEDALRLLISVLAGYPLAVVHRTFFYNKPAQHQHLFFVIVGLSLWMFNCGSSVIHPILSIFGAFFITNFMAGTDASIYAAHIVFLGHLLIGYWFHETDTYDITWTTPFCIMTLRFIGLVMDVYDGAQKPEHLKPDQKLTAISDKPGLLEIAAFGLFFQGTLVGPQFTLSKFRSFVNGDWLDSDGQPPKSAFLPSIGRFLAGCTYMVLHQWGQFWIPDQYFNSDAYNNLSFFWRWSWVTLWFRLTMYKYCAMWLITEGASILSGLGHNGKDAEGNDRWDGVRDLHIIKWETGHDYNSVVESFNCGTNT... | lipid modification nematode larval development phosphatidylcholine biosynthetic process phosphatidylethanolamine biosynthetic process phosphatidylserine biosynthetic process positive regulation of growth rate post-embryonic body morphogenesis endoplasmic reticulum; endoplasmic reticulum membrane; membrane 1-acylglycero... |
positive regulation of proteasomal ubiquitin-dependent protein catabolic process protein polyubiquitination ubiquitin-dependent protein catabolic process | cytoplasm; nucleus; ubiquitin ligase complex | ubiquitin conjugating enzyme binding ubiquitin protein ligase activity zinc ion binding | Caenorhabditis elegans | Cytoplasm Metal-binding Nucleus Reference proteome Repeat Transferase Ubl conjugation pathway Zinc Zinc-finger | MSSDDEINMD | MSSDDEINMDDSDSSQGEIDDGCMSDDDGIVLESREQNSSDYKDNGEPDNEVLNHDSLEAEMKKTITDVQAVLQVKTGVCRILLHKYKWNKESLLERFYEHPDTTTFLIDAHVIPRRQERLPAGDAECDICCSLGELSGLSCNHRACTQCWKAYLTNKIANNAQSEIECMAPNCKLLIEDEKVMFYITDPTVIATYRKLIVASYVETNRLLKWCPGIDCGKAVRVSHWEPRLVVCSCGSRFCFSCGHDWHEPVNCRLLKLWLKKCNDDSETSNWINANTKECPKCMITIEKDGGCNHMTCKNTACRFEFCWMCLGPWEPH... | positive regulation of proteasomal ubiquitin-dependent protein catabolic process protein polyubiquitination ubiquitin-dependent protein catabolic process cytoplasm; nucleus; ubiquitin ligase complex ubiquitin conjugating enzyme binding ubiquitin protein ligase activity zinc ion binding Caenorhabditis elegansCytoplasm M... |
chromosome segregation mitotic cytokinesis nuclear envelope organization response to X-ray | nuclear envelope; nuclear inner membrane | lamin binding | Caenorhabditis elegans | Cell cycle Membrane Nucleus Reference proteome Transmembrane Transmembrane helix | MDVSQLTDAE | MDVSQLTDAELRDSLKSHGVSVGPIVATTRKLYEKKLIKLSDGSINNQSNLNDSQFNEDSLIISSSPKKSPPQRVFQNVSAATAAATTSPESDSDDCEESMRYLTEEEMAADRASARQAQSNKGGFLGSTITFTILFVFIAVFAYFLIENAEQLKLVAETNPEDTI | chromosome segregation mitotic cytokinesis nuclear envelope organization response to X-ray nuclear envelope; nuclear inner membrane lamin binding Caenorhabditis elegansCell cycle Membrane Nucleus Reference proteome Transmembrane Transmembrane helix MDVSQLTDAE MDVSQLTDAELRDSLKSHGVSVGPIVATTRKLYEKKLIKLSDGSINNQSNLNDSQFNEDS... |
apoptotic process cellular response to starvation execution phase of apoptosis negative regulation of neuromuscular synaptic transmission negative regulation of Toll signaling pathway neuron remodeling nurse cell apoptotic process oogenesis ovarian nurse cell to oocyte transport positive regulation of autophagy positiv... | cytoplasm; cytosol; messenger ribonucleoprotein complex; mitochondrion; neuronal cell body; neuronal ribonucleoprotein granule | BIR domain binding cysteine-type endopeptidase activity cysteine-type endopeptidase activity involved in execution phase of apoptosis | Drosophila melanogaster | Apoptosis Direct protein sequencing Hydrolase Protease Reference proteome Thiol protease Zymogen | MTDECVTRNY | MTDECVTRNYGVGIRSPNGSENRGSFIMADNTDAKGCTPESLVVGGATAASPLPANKFVARMPVERYASEYNMSHKHRGVALIFNHEFFDIPSLKSRTGTNVDAQELKKAFENLGFAVSVHKDCKLRDILKHVGKAAELDHTDNDCLAVAILSHGEHGYLYAKDTQYKLDNIWHYFTATFCPSLAGKPKLFFIQACQGDRLDGGITLEKGVTETDGESSTSYKIPIHADFLFSYSTIPGYFSWRNINNGSWYMQSLIRELNANGKKYDLLTLLTFVNQRVALDFESNVPATPMMDRQKQIPCLTSMLTRILRFGDKPNGN... | apoptotic process cellular response to starvation execution phase of apoptosis negative regulation of neuromuscular synaptic transmission negative regulation of Toll signaling pathway neuron remodeling nurse cell apoptotic process oogenesis ovarian nurse cell to oocyte transport positive regulation of autophagy positiv... |
amyloid precursor protein catabolic process amyloid-beta metabolic process calcium ion transport egg-laying behavior embryo development ending in birth or egg hatching gonad development membrane protein ectodomain proteolysis negative regulation of apoptotic process nematode larval development Notch receptor processing... | apical plasma membrane; cell cortex; cell surface; ciliary rootlet; dendritic shaft; endoplasmic reticulum membrane; Golgi membrane; growth cone; lysosomal membrane; membrane raft; mitochondrial inner membrane; neuromuscular junction; neuronal cell body; nucleus; perinuclear region of cytoplasm; Z disc | aspartic endopeptidase activity, intramembrane cleaving endopeptidase activity | Caenorhabditis elegans | Endoplasmic reticulum Golgi apparatus Membrane Notch signaling pathway Reference proteome Transmembrane Transmembrane helix | MPRTKRVYSG | MPRTKRVYSGKTITGVLYPVAICMLFVAINVKLSQPEQQEQSKVVYGLFHSYDTADSGTITLYLIGFLILTTSLGVFCYQMKFYKAIKVYVLANSIGILLVYSVFHFQRIAEAQSIPVSVPTFFFLILQFGGLGITCLHWKSHRRLHQFYLIMLAGLTAIFILNILPDWTVWMALTAISFWDIVAVLTPCGPLKMLVETANRRGDDKFPAILYNSSSYVNEVDSPDTTRSNSTPLTEFNNSSSSRLLESDSLLRPPVIPRQIREVREVEGTIRLGMGDFVFYSLMLGNTVQTCPLPTVVACFVSNLVGLTITLPIVTLSQ... | amyloid precursor protein catabolic process amyloid-beta metabolic process calcium ion transport egg-laying behavior embryo development ending in birth or egg hatching gonad development membrane protein ectodomain proteolysis negative regulation of apoptotic process nematode larval development Notch receptor processing... |
chromatin remodeling positive regulation of double-strand break repair regulation of G1/S transition of mitotic cell cycle regulation of mitotic metaphase/anaphase transition regulation of nucleotide-excision repair regulation of transcription by RNA polymerase II | condensed chromosome; nuclear envelope; nucleoplasm; nucleus; SWI/SNF complex | RNA polymerase II-specific DNA-binding transcription factor binding transcription coregulator activity | Caenorhabditis elegans | Chromatin regulator Chromosome Nucleus Reference proteome Transcription Transcription regulation | MHSQQRPNPQ | MHSQQRPNPQMNRHPYGTPGSAPQMRRPGGFAGQPPQMHGPRMVAPPAAPLPKKKKYADKCIHPKIRELEPDAENYMALLASEQKLDSTLSRKKLDIQEALKRPSKVKKRLRIYISHTFIEEKQPEKDTDEASLPMWELRVEGRLLDEQPPAPAIPGQRPVPKRKFSSFFKSLVIELDKEMYGPDQHLVEWHRTPQTNETDGFQVKRAGDRPVKCRILLLLDNHPAKFKLHPRLAKVLGIATETRPKIIEALWQYIKTHGLQDPQERDIINCDTFLSQCFGVNRMRFMEVPNKLHQLLQQTDPLEFNHIIQRPKEGQEQV... | chromatin remodeling positive regulation of double-strand break repair regulation of G1/S transition of mitotic cell cycle regulation of mitotic metaphase/anaphase transition regulation of nucleotide-excision repair regulation of transcription by RNA polymerase II condensed chromosome; nuclear envelope; nucleoplasm; nu... |
anatomical structure development cell differentiation defense response to Gram-negative bacterium negative regulation of protein localization to nucleus regulation of innate immune response regulation of transcription by RNA polymerase II | nucleus | nuclear receptor activity RNA polymerase II cis-regulatory region sequence-specific DNA binding steroid hormone binding zinc ion binding | Caenorhabditis elegans | Alternative splicing DNA-binding Metal-binding Nucleus Receptor Reference proteome Transcription Transcription regulation Zinc Zinc-finger | MDFLISTSLS | MDFLISTSLSESTSTSADFCVVCGDKAIGKHYGAVACNGCKGFFRRSVWQNLQYTCRFNKQCNIDKDHRNACRYCRFQKCLADGMKPEAIQNERDRIGSTKRRKRSGANSENNSDSEGTPSPKIEVMGNSVSRKLIEMLLDIEHRLASNQSMNALLRDESEMKNSRQRAVNYLIGWTNMLHPLPEVPLADKVLLLKKFSSAFTLLGTLQRSMALPHFVLPNDQVLSISASHPPELFEALTRIIDELLTPLRRLRTDHAEFSCLKALLLLNPDVVGISNNTRERIREARDALLKTLFAYMSNTQNSIDASLRVSSLLMIIP... | anatomical structure development cell differentiation defense response to Gram-negative bacterium negative regulation of protein localization to nucleus regulation of innate immune response regulation of transcription by RNA polymerase II nucleus nuclear receptor activity RNA polymerase II cis-regulatory region sequenc... |
DNA damage response, signal transduction by p53 class mediator DNA repair-dependent chromatin remodeling dosage compensation by hyperactivation of X chromosome negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II ... | MSL complex; NSL complex; nuclear chromosome; nucleus; polytene chromosome interband; transcription regulator complex; X chromosome; X chromosome located dosage compensation complex, transcription activating | chromatin binding histone acetyltransferase activity histone H4K16 acetyltransferase activity metal ion binding transcription coregulator activity | Drosophila melanogaster | 3D-structure Acetylation Acyltransferase Chromatin regulator Chromosome Metal-binding Nucleus Reference proteome Transferase Zinc Zinc-finger | MSEAELEQTP | MSEAELEQTPSAGHVQEQPIEEEHEPEQEPTDAYTIGGPPRTPVEDAAAELSASLDVSGSDQSAEQSLDLSGVQAEAAAESEPPAKRQHRDISPISEDSTPASSTSTSSTRSSSSSRYDDVSEAEEAPPEPEPEQPQQQQQEEKKEDGQDQVKSPGPVELEAQEPAQPQKQKEVVDQEIETEDEPSSDTVICVADINPYGSGSNIDDFVMDPDAPPNAIITEVVTIPAPLHLKGTQQLGLPLAAPPPPPPPPAAEQVPETPASPTDDGEEPPAVYLSPYIRSRYMQESTPGLPTRLAPRDPRQRNMPPPAVVLPIQTVLS... | DNA damage response, signal transduction by p53 class mediator DNA repair-dependent chromatin remodeling dosage compensation by hyperactivation of X chromosome negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II ... |
amyloid precursor protein catabolic process amyloid-beta formation amyloid-beta metabolic process apoptotic process calcium ion transport membrane protein ectodomain proteolysis negative regulation of apoptotic process Notch receptor processing Notch receptor processing, ligand-dependent Notch signaling pathway protein... | apical plasma membrane; cell cortex; cell surface; ciliary rootlet; dendritic shaft; endoplasmic reticulum membrane; gamma-secretase complex; Golgi membrane; growth cone; lysosomal membrane; membrane raft; mitochondrial inner membrane; neuromuscular junction; neuronal cell body; nucleus; perinuclear region of cytoplasm... | aspartic endopeptidase activity, intramembrane cleaving endopeptidase activity | Drosophila melanogaster | Alternative splicing Endoplasmic reticulum Glycoprotein Golgi apparatus Hydrolase Membrane Notch signaling pathway Protease Reference proteome Transmembrane Transmembrane helix | MAAVNLQASC | MAAVNLQASCSSGLASEDDANVGSQIGAAERLERPPRRQQQRNNYGSSNQDQPDAAILAVPNVVMREPCGSRPSRLTGGGGGSGGPPTNEMEEEQGLKYGAQHVIKLFVPVSLCMLVVVATINSISFYNSTDVYLLYTPFHEQSPEPSVKFWSALANSLILMSVVVVMTFLLIVLYKKRCYRIIHGWLILSSFMLLFIFTYLYLEELLRAYNIPMDYPTALLIMWNFGVVGMMSIHWQGPLRLQQGYLIFVAALMALVFIKYLPEWTAWAVLAAISIWDLIAVLSPRGPLRILVETAQERNEQIFPALIYSSTVVYALVN... | amyloid precursor protein catabolic process amyloid-beta formation amyloid-beta metabolic process apoptotic process calcium ion transport membrane protein ectodomain proteolysis negative regulation of apoptotic process Notch receptor processing Notch receptor processing, ligand-dependent Notch signaling pathway protein... |
adenylate cyclase-activating adrenergic receptor signaling pathway dopamine receptor signaling pathway octopamine or tyramine signaling pathway | membrane; plasma membrane | G protein-coupled amine receptor activity octopamine receptor activity tyramine receptor activity | Caenorhabditis elegans | Alternative promoter usage Alternative splicing Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MFRNYTDSVQ | MFRNYTDSVQEMVLRAIDSIRDSVINASSAVSTTTLPPLDIPMTSMKPPSIIPTVELVLGTITYLVIIAMTVVGNTLVVVAVFSYRPLKKVQNYFLVSLAASDLAVAIFVMPLHVVTFLAGGKWLLGVTVCQFFTTADILLCTSSILNLCAIALDRYWAIHNPINYAQKRTTKFVCIVIVIVWILSMLISVPPIIGWNNWQENMMEDSCGLSTEKAFVVFSAAGSFFLPLLVMVVVYVKIFISARQRIRTNRGRSALMRIQNAEGDDDYRKMSIKRASVESARTSSRVGEKTPLVIADGQTTVTTLAAHSTDGGSLPKDE... | adenylate cyclase-activating adrenergic receptor signaling pathway dopamine receptor signaling pathway octopamine or tyramine signaling pathway membrane; plasma membrane G protein-coupled amine receptor activity octopamine receptor activity tyramine receptor activity Caenorhabditis elegansAlternative promoter usage Alt... |
cortical cytoskeleton organization embryo development ending in birth or egg hatching microtubule cytoskeleton organization mitotic spindle assembly mitotic spindle organization positive regulation of B cell differentiation protein localization to organelle regulation of dephosphorylation | centrosome; cytoplasm; protein phosphatase type 2A complex | protein phosphatase 2A binding | Caenorhabditis elegans | Alternative splicing Cell cycle Cytoplasm Cytoskeleton Reference proteome | MPTDEPSKRK | MPTDEPSKRKSILPTIPTSLMLKKSNEALSDFERTFNDRVMDIFAENRRIDVEEFKKNAECFLNIIRSNKIDLNWGEGGESRYVTITRLMKILKTSPQSIKDLLPHNTVSNFVKITNYNLTIDITLLEELVRTVIHAEESYIKLLPFSENSTEISSYSLQDFVATHFIPIMIEEPENPVYYTAYAVGTIFFLLGARRRDCVYLKDLLASTLLLQLEECIHAENHCLSPPKIDVFTVAQFRTTLSEFRFLDSQRKGLLAPADLKFFRDGIFNEVFTKRIFEISITYEDGRIDFKAFVDFVTALKFRHTTASAKYHFEILDL... | cortical cytoskeleton organization embryo development ending in birth or egg hatching microtubule cytoskeleton organization mitotic spindle assembly mitotic spindle organization positive regulation of B cell differentiation protein localization to organelle regulation of dephosphorylation centrosome; cytoplasm; protein... |
cell fate specification determination of adult lifespan intracellular receptor signaling pathway neurogenesis positive regulation of transcription by RNA polymerase II protein maturation by protein folding regulation of transcription by RNA polymerase II response to xenobiotic stimulus social behavior | aryl hydrocarbon receptor complex; cytoplasm; nucleus; protein folding chaperone complex; RNA polymerase II transcription regulator complex | DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II-specific DNA-binding transcription factor binding | Caenorhabditis elegans | Alternative splicing Developmental protein DNA-binding Nucleus Receptor Reference proteome Repeat Transcription Transcription regulation | MAQDIFMDPW | MAQDIFMDPWQSATSFAMEDEDMGMPSGKYARMEDEMGENKERFARENHSEIERRRRNKMTHYINELAEMVPQCASLGRKPDKLTILRMAVSHMKGIRGHTAQDETSYKPSFLTDQELKHLILEAANGFLFVVCCQTGKVLYVADSITPVLNLKQEDWLQRNLNELIHPDDQDKIRDQLCGSEVSVNKVLDLKSGSVKREGASTRVHMSCRRGFICRMRVGALEPLHRLRNRRPLFQHAGQNYVVMHCTGYIKNAPPQGINAPASSCLVAIARLQVASMPVCADPTSTNQFSVRVSEDGKMTFIDARVSDLIGLSSDQLI... | cell fate specification determination of adult lifespan intracellular receptor signaling pathway neurogenesis positive regulation of transcription by RNA polymerase II protein maturation by protein folding regulation of transcription by RNA polymerase II response to xenobiotic stimulus social behavior aryl hydrocarbon ... |
acetylcholine biosynthetic process choline transport | axon; neuron projection; neuronal cell body; plasma membrane; synapse; synaptic vesicle | choline transmembrane transporter activity choline:sodium symporter activity | Caenorhabditis elegans | Glycoprotein Ion transport Membrane Neurotransmitter biosynthesis Reference proteome Sodium Sodium transport Symport Transmembrane Transmembrane helix Transport | MADLLGIVAI | MADLLGIVAIVFFYVLILVVGIWAGRKSKSSKELESEAGAATEEVMLAGRNIGTLVGIFTMTATWVGGAYINGTAEALYNGGLLGCQAPVGYAISLVMGGLLFAKKMREEGYITMLDPFQHKYGQRIGGLMYVPALLGETFWTAAILSALGATLSVILGIDMNASVTLSACIAVFYTFTGGYYAVAYTDVVQLFCIFVGLWVCVPAAMVHDGAKDISRNAGDWIGEIGGFKETSLWIDCMLLLVFGGIPWQVYFQRVLSSKTAHGAQTLSFVAGVGCILMAIPPALIGAIARNTDWRMTDYSPWNNGTKVESIPPDKRNM... | acetylcholine biosynthetic process choline transport axon; neuron projection; neuronal cell body; plasma membrane; synapse; synaptic vesicle choline transmembrane transporter activity choline:sodium symporter activity Caenorhabditis elegansGlycoprotein Ion transport Membrane Neurotransmitter biosynthesis Reference prot... |
negative regulation of transcription by RNA polymerase II nematode larval development neuron development neuron fate determination neuron fate specification positive regulation of neuron differentiation positive regulation of transdifferentiation | nucleus | zinc ion binding | Caenorhabditis elegans | Alternative splicing Metal-binding Neurogenesis Nucleus Reference proteome Repeat Repressor Transcription Transcription regulation Zinc Zinc-finger | MSSISNNPDF | MSSISNNPDFSSIDPAVLMSLLMKSSGSLPTPPDTHSDGSESPDSTASDSSDKKRRRKPESKDIVRVAEEAEAAAATCSSIPSSSDTKENETEEDQNMTCDTTTNNAQKPTEQTATSADVVTSSVPSGLEGVPSFLFSQFMAPSFQKQLEIFTSGNMMSATHSDTSPSDVDSVLDGGVVTAEETSSSKSPMMTSSDTPKTPLTASSPPHSSGSESRVMSPITHTNISDELSISTTPTVAFTPNGSIPSPGTGYSWSIRREGKLACPTPGCDGSGHQTGLYTHHRSLSGCPRRPDKTVIQMLALRQDTVLRCTTAGCSGKG... | negative regulation of transcription by RNA polymerase II nematode larval development neuron development neuron fate determination neuron fate specification positive regulation of neuron differentiation positive regulation of transdifferentiation nucleus zinc ion binding Caenorhabditis elegansAlternative splicing Metal... |
autophagy lipid metabolic process regulation of DNA-templated transcription response to starvation triglyceride metabolic process | nucleus | DNA-binding transcription factor activity RNA polymerase II cis-regulatory region sequence-specific DNA binding zinc ion binding | Caenorhabditis elegans | Alternative splicing DNA-binding Metal-binding Nucleus Receptor Reference proteome Transcription Transcription regulation Zinc Zinc-finger | MFSTLSPSAI | MFSTLSPSAIDDILRHAVHFGQGTTAIAPSPVTFISTTTQQSLGATYPGVFNPTTPTFNHYQHQALPVTMHTSTSSAHHTTTGHGRGRRKNSTINLVCVVCGDQAFGKHYGVNACNGCKGFFRRSVWHNRQYLCRFEGRCAIAKEHRNVCRACRLKQCFVAGMNPRAVQSERVEREQNGSPNQIEEDDYKDLSSPDTCSVEIQTDVDEQKPSSNNSAPLPSMELEMAKLSEQIVEMHRAVCSYVDPVTKRENFDMKMETETTKIAFMNAFYNPEMIGPRTPLDITGRRVATVKDVMDEWKRNFVLFSDWLRALPEYNQMS... | autophagy lipid metabolic process regulation of DNA-templated transcription response to starvation triglyceride metabolic process nucleus DNA-binding transcription factor activity RNA polymerase II cis-regulatory region sequence-specific DNA binding zinc ion binding Caenorhabditis elegansAlternative splicing DNA-bindin... |
aerotaxis behavior cGMP-mediated signaling defense response to Gram-negative bacterium response to hyperoxia response to oxygen levels | dendrite; guanylate cyclase complex, soluble; neuronal cell body | carbon monoxide binding GTP binding guanylate cyclase activity heme binding metal ion binding nitric oxide binding oxygen binding oxygen sensor activity | Caenorhabditis elegans | Behavior Cell projection cGMP biosynthesis Coiled coil Cytoplasm GTP-binding Heme Iron Lyase Magnesium Metal-binding Nucleotide-binding Reference proteome | MFGWIHESFR | MFGWIHESFRQLVTRKYGKDIWEKIVHMSKFELGTESEIAHYYNDDETLRLVNSMANVIGIPIEEIWEAYGGFLIQFTMETGWDELLRAMAPDLEGFLDSLDSLHYFIDHVVYKTKLRGPSFRCDVQADGTLLLHYYSKRSGLYPIVKGVVREVARRIYDTEVVMKVQERKQEHLDAFVTEHVVFVITQIENANSTQPKSISSKADSQIDLSTGIYEISSSDFSLAFPYHICFDPDLFVEHFGNFIKKTFPNAMRQETRVTDLLELVHPEVPFSYESIKYYKNSLFVFRLKGLGDIVHNANDEAKTVLLKGSMVFIDEGK... | aerotaxis behavior cGMP-mediated signaling defense response to Gram-negative bacterium response to hyperoxia response to oxygen levels dendrite; guanylate cyclase complex, soluble; neuronal cell body carbon monoxide binding GTP binding guanylate cyclase activity heme binding metal ion binding nitric oxide binding oxyge... |
fatty acid transport lipid transport long-chain fatty acid transport | cytosol; lysosome; nucleus | fatty acid binding lipid binding long-chain fatty acid binding long-chain fatty acid transporter activity oleic acid binding | Caenorhabditis elegans | 3D-structure Lipid-binding Lysosome Nucleus Reference proteome Transport | MVSMKEFIGR | MVSMKEFIGRWKLVHSENFEEYLKEIGVGLLIRKAASLTSPTLEIKLDGDTWHFNQYSTFKNNKLAFKIREKFVEIAPDERSYNTLVTFENGKFISHQDKIKENHHSSVFTTWLENGKLLQTYQSGSVICRREFVKE | fatty acid transport lipid transport long-chain fatty acid transport cytosol; lysosome; nucleus fatty acid binding lipid binding long-chain fatty acid binding long-chain fatty acid transporter activity oleic acid binding Caenorhabditis elegans3D-structure Lipid-binding Lysosome Nucleus Reference proteome Transport MVSM... |
cell fate commitment cell fate specification negative regulation of transcription by RNA polymerase II neuron differentiation neuron fate specification positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II | nucleus | DNA binding sequence-specific DNA binding | Caenorhabditis elegans | Developmental protein DNA-binding Nucleus Reference proteome Transcription Transcription regulation | MSVRIDEPQL | MSVRIDEPQLFVSMSKEPTQETVNVGGHHDDSSSNCDERVDDQTEEQKSPPASPDLTANLNVFDLESRQKVVQRLLNSQLNLSNLRAPLNLPPIFQALQGPFSIQQQLLGLASGLTAISPGLDDYDEENTNQGEPEDLTLGGFRKETSVKSEEPSESGINASGPAWSYEEQFKQLYELSDDVKRKEWLDDWLNFMHRIGKPVTRIPIMAKQVLDLYELYRLVVQHGGLVEIINKKLWREITKGLNLPSSITSAAFTLRTQYQKYLYDYECEKEKLSNQSDLQQAIDGNRREAPGRRTAPSFPLPFQLPHAASAAATMLNN... | cell fate commitment cell fate specification negative regulation of transcription by RNA polymerase II neuron differentiation neuron fate specification positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II nucleus DNA binding sequence-specific DNA binding Caenorhabdi... |
cell-cell adhesion heterochromatin formation nuclear envelope organization nuclear migration nuclear pore localization protein localization to nuclear envelope | hemidesmosome; intermediate filament; nuclear envelope; nuclear lamina | structural constituent of cytoskeleton | Caenorhabditis elegans | Cell junction Coiled coil Intermediate filament Reference proteome | MTDPDSYRSS | MTDPDSYRSSITSRPSFNRTVTSSSQNYGAPGSGNRVLKIVTETHSSSVSSGLSPYGQNAASTIRDNREREKKEIMELNDRLASYIEKVRFLDAQNRKLDADLKMLQGRFGKSTGSVKVMYEMEITTATNVVKQTGKDHGETEKEIRKLQDQLDELRKKFEEAQRGRAEDRLKIDDLLVTLSNLEAEINLLKRRIALLEEEVARLKKENFRLTSELQRVRIELDQETLLRIDNQNKVKTILEEIDFMKRGFETELKELQAQAARDTTSENREYFKNELANAMRDIRAEYDQIMNGNRNDMESWYQLRVQEINTQSNRQNA... | cell-cell adhesion heterochromatin formation nuclear envelope organization nuclear migration nuclear pore localization protein localization to nuclear envelope hemidesmosome; intermediate filament; nuclear envelope; nuclear lamina structural constituent of cytoskeleton Caenorhabditis elegansCell junction Coiled coil In... |
courtship behavior olfactory behavior response to ethanol response to pheromone sensory perception of smell | extracellular region | dibutyl phthalate binding diphenyl phthalate binding odorant binding pheromone binding | Drosophila melanogaster | 3D-structure Behavior Disulfide bond Olfaction Pheromone response Pheromone-binding Reference proteome Secreted Sensory transduction Signal Transport | MKHWKRRSSA | MKHWKRRSSAVFAIVLQVLVLLLPDPAVAMTMEQFLTSLDMIRSGCAPKFKLKTEDLDRLRVGDFNFPPSQDLMCYTKCVSLMAGTVNKKGEFNAPKALAQLPHLVPPEMMEMSRKSVEACRDTHKQFKESCERVYQTAKCFSENADGQFMWP | courtship behavior olfactory behavior response to ethanol response to pheromone sensory perception of smell extracellular region dibutyl phthalate binding diphenyl phthalate binding odorant binding pheromone binding Drosophila melanogaster 3D-structure Behavior Disulfide bond Olfaction Pheromone response Pheromone-bind... |
chondroitin sulfate biosynthetic process epithelial cell migration, open tracheal system fibroblast growth factor receptor signaling pathway glycosaminoglycan biosynthetic process heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process mesoderm migration involved in gastrulation seg... | nucleus | NAD binding UDP-glucose 6-dehydrogenase activity | Drosophila melanogaster | NAD Oxidoreductase Reference proteome Wnt signaling pathway | MKVCCIGAGY | MKVCCIGAGYVGGPTCAVMALKCPDIVITLVDKSSERIAQWNSDKLPIYEPGLDEVVKKCRNVNLFFSTDIETAIKEADLIFISVNTPTKTCGNGKGRAADLKYVESAARMIAEIAQSNKIVVEKSTVPVRAAESIMHILRANQKPGIHYDILSNPEFLAEGTAINDLLNADRVLIGGEETPEGHQAVEKLSWIYEHWIPKQNILTTNTWSSELSKLAANAFLAQRISSINSLSAVCEATGADVSEVARAVGLDSRIGSKFLQASVGFGGSCFQKDILNLIYICENLNLPEVAAYWQQVIDMNEYQKRRFSQKIIESLFN... | chondroitin sulfate biosynthetic process epithelial cell migration, open tracheal system fibroblast growth factor receptor signaling pathway glycosaminoglycan biosynthetic process heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process mesoderm migration involved in gastrulation seg... |
chemical synaptic transmission negative regulation of canonical Wnt signaling pathway negative regulation of DNA-templated transcription regulation of axonogenesis regulation of synapse structure or activity | nucleus; synapse; transcription regulator complex | RNA polymerase II-specific DNA-binding transcription factor binding transcription corepressor activity | Caenorhabditis elegans | Developmental protein Nucleus Reference proteome Repeat Transcription Transcription regulation WD repeat | MKASYLETLD | MKASYLETLDRIKDEHAEMSKHVNQQRSDIEKVALEKENMNRSYMTYAEVSNTLRSDLRKAEEINKRLQEFIMQSLAPQLSQDNQANCLAALEAFKTASPRENGNGAPALPPGFPPGAAGMLGMMPNMPFGMSPAMSQLFNQFASPHVNGGDGAGGSSGGASEAKKAKLEDPDDGELEIDVTNDDHPSTASNGGAANKNGRDSTNSVASSGASTPSIASNSRARQQQQPLAGLQGLEQMNFLAGFNPNLLRQASAAGGFNFLNDPHAQARLAAAIGQIGSRPAYSFKIVDGGVPTPTSFPPDAQKGPGIPTGLKKKMELN... | chemical synaptic transmission negative regulation of canonical Wnt signaling pathway negative regulation of DNA-templated transcription regulation of axonogenesis regulation of synapse structure or activity nucleus; synapse; transcription regulator complex RNA polymerase II-specific DNA-binding transcription factor bi... |
defecation nematode larval development regulation of hindgut contraction regulation of nematode pharyngeal pumping synaptic transmission, cholinergic synaptic vesicle exocytosis vesicle fusion | axon; cortical granule; neuron projection; plasma membrane; presynaptic active zone; SNARE complex; synaptic vesicle; synaptic vesicle membrane | SNAP receptor activity syntaxin binding | Caenorhabditis elegans | Cell membrane Coiled coil Cytoplasmic vesicle Membrane Reference proteome Synapse Synaptosome Transmembrane Transmembrane helix | MDAQGDAGAQ | MDAQGDAGAQGGSQGGPRPSNKRLQQTQAQVDEVVGIMKVNVEKVLERDQKLSQLDDRADALQEGASQFEKSAATLKRKYWWKNIKMMIIMCAIVVILIIIIVLWAGGK | defecation nematode larval development regulation of hindgut contraction regulation of nematode pharyngeal pumping synaptic transmission, cholinergic synaptic vesicle exocytosis vesicle fusion axon; cortical granule; neuron projection; plasma membrane; presynaptic active zone; SNARE complex; synaptic vesicle; synaptic ... |
spermidine biosynthetic process spermine biosynthetic process | cytosol | adenosylmethionine decarboxylase activity | Caenorhabditis elegans | Autocatalytic cleavage Decarboxylase Lyase Polyamine biosynthesis Pyruvate Reference proteome S-adenosyl-L-methionine Schiff base Spermidine biosynthesis Zymogen | MSATSATNFA | MSATSATNFAVQTHPVKAPDEEYFFEGAEKLLELWFCSSTQNETRSLRIIPREEIDAMLDIARCKILHSKHNESIDSYVLSESSLFISDNRVILKTCGTTRLLAALPVIMQLAGAYAGLDQVQSVYYSRKNFLRPDLQPSLHKNFDAEVEYLDSFFVDGHAYCLGSLKQDRWYLYTFHREVEFPAHKQPDHTLEILMSDLDEEVLHKFTKDYAVDGNDCFMRAGIDKIIPAGADVHDELFDPCGYSMNAYMNDTDQYATIHVTPEKAFSFASFETNQDLVCLYSQTRKVLQCFRPNKILMTVFANDISEKGKDAQQQLWD... | spermidine biosynthetic process spermine biosynthetic process cytosol adenosylmethionine decarboxylase activity Caenorhabditis elegansAutocatalytic cleavage Decarboxylase Lyase Polyamine biosynthesis Pyruvate Reference proteome S-adenosyl-L-methionine Schiff base Spermidine biosynthesis Zymogen MSATSATNFA MSATSATNFAVQT... |
amoeboid sperm motility cell differentiation egg-laying behavior male meiosis chromosome segregation regulation of pseudopodium assembly reproduction spermatogenesis | chromatin; cytoplasm; nucleus; pseudopodium | metal ion binding myosin phosphatase activity protein serine/threonine phosphatase activity | Caenorhabditis elegans | Cell projection Chromosome Cytoplasm Differentiation Hydrolase Manganese Metal-binding Protein phosphatase Reference proteome Spermatogenesis | MTAPMDVDNL | MTAPMDVDNLMSRLLNVGMSGGRLTTSVNEQELQTCCAVAKSVFASQASLLEVEPPIIVCGDIHGQYSDLLRIFDKNGFPPDVNFLFLGDYVDRGRQNIETICLMLCFKIKYPENFFMLRGNHECPAINRVYGFYEECNRRYKSTRLWSIFQDTFNWMPLCGLIGSRILCMHGGLSPHLQTLDQLRQLPRPQDPPNPSIGIDLLWADPDQWVKGWQANTRGVSYVFGQDVVADVCSRLDIDLVARAHQVVQDGYEFFASKKMVTIFSAPHYCGQFDNSAATMKVDENMVCTFVMYKPTPKSMRRG | amoeboid sperm motility cell differentiation egg-laying behavior male meiosis chromosome segregation regulation of pseudopodium assembly reproduction spermatogenesis chromatin; cytoplasm; nucleus; pseudopodium metal ion binding myosin phosphatase activity protein serine/threonine phosphatase activity Caenorhabditis ele... |
activation of adenylate cyclase activity adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting serotonin receptor signaling pathway chemical synaptic transmission G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger positive regulat... | dendrite; plasma membrane; receptor complex; synapse | beta-adrenergic receptor activity beta3-adrenergic receptor activity G protein-coupled serotonin receptor activity neurotransmitter receptor activity protein homodimerization activity serotonin binding | Canis lupus familiaris | 3D-structure Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MAPWPHGNGS | MAPWPHGNGSVASWPAAPTPTPDAANTSGLPGAPWAVALAGALLALEVLATVGGNLLVIVAIARTPRLQTMTNVFVTSLATADLVVGLLVVPPGATLALTGRWPLGATGCELWTSVDVLCVTASIETLCALAVDRYLAVTNPLRYGALVTKRRARAAVVLVWVVSAAVSFAPIMSKWWRVGADAEAQRCHSNPHCCAFASNIPYALLSSSVSFYLPLLVMLFVYARVFLVATRQLRLLRRELGRFPPAESPPAASRSRSPGPARRCASPAAVPSDRLRPARLLPLREHRALRTLGLIVGTFTLCWLPFFVANVMRALGGP... | activation of adenylate cyclase activity adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting serotonin receptor signaling pathway chemical synaptic transmission G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger positive regulat... |
androgen metabolic process bile acid biosynthetic process brexanolone metabolic process C21-steroid hormone metabolic process estrogen metabolic process fatty acid beta-oxidation fatty acid metabolic process isoleucine catabolic process mitochondrial tRNA 3'-end processing mitochondrial tRNA 5'-end processing mitochond... | mitochondrial nucleoid; mitochondrial ribonuclease P complex; mitochondrion | 17-beta-hydroxysteroid dehydrogenase (NAD+) activity 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity 3-hydroxyacyl-CoA dehydrogenase activity androstan-3-alpha,17-beta-diol dehydrogenase activity chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity cholate 7-alpha-dehydrogenase activity estradiol 17-beta-dehydr... | Bos taurus | Acetylation Direct protein sequencing Fatty acid metabolism Lipid metabolism Mitochondrion Mitochondrion nucleoid NAD Oxidoreductase Reference proteome Steroid metabolism tRNA processing | MAAACRSVKG | MAAACRSVKGLVALITGGASGLGLATAERLVGQGATAVLLDLPNSDGETQAKKLGKSCAFAPADVTSEKDVQAALTLAREKFGRVDVAVNCAGIAVASKTYNLKKSQAHTLEDFQRVINVNLIGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPMGIRVMTIAPGLFGTPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQAIIENSFLNGEVIRLDGAIRMQP | androgen metabolic process bile acid biosynthetic process brexanolone metabolic process C21-steroid hormone metabolic process estrogen metabolic process fatty acid beta-oxidation fatty acid metabolic process isoleucine catabolic process mitochondrial tRNA 3'-end processing mitochondrial tRNA 5'-end processing mitochond... |
dephosphorylation insulin secretion involved in cellular response to glucose stimulus lipid metabolic process neurotransmitter secretion | secretory granule membrane; synaptic vesicle membrane | protein tyrosine phosphatase activity | Macaca nemestrina | Acetylation Cytoplasmic vesicle Glycoprotein Hydrolase Lipid metabolism Membrane Phospholipid metabolism Phosphoprotein Protein phosphatase Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix | MALPLLLLLL | MALPLLLLLLLLLPPRVLPAAPSSVPHGRQLPGRLGCLLEEGLCGASEACVNDGVFGRCQKVPAMDFYRYEVSPVALQRLRVALQKLSGTGFTWQDDYTQYVMDQELADLPKTYLRHPEASGPARPSKHSIGSERRYSQEGGAALAKAFRRHLPFLEALSQAPASDALARTRMAQDRPRAEGDDRFSKSILTYVAHTSVLTYPPGPQAQLPEDLLPRTLSQLQPDELSPKVDSSVERHHLMAALSAYAAQRPPAPPGKGSLEPQYLLRAPSRMPRPLLSPAVPQKWPSPLGDPEDPPSTGEGARIHTLLKDLQRQPAEAR... | dephosphorylation insulin secretion involved in cellular response to glucose stimulus lipid metabolic process neurotransmitter secretion secretory granule membrane; synaptic vesicle membrane protein tyrosine phosphatase activity Macaca nemestrina Acetylation Cytoplasmic vesicle Glycoprotein Hydrolase Lipid metabolism M... |
G protein-coupled receptor signaling pathway phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of MAP kinase activity positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction | cytoplasm; membrane; nucleus; phosphatidylinositol 3-kinase complex; phosphatidylinositol 3-kinase complex, class IB; plasma membrane | 1-phosphatidylinositol-3-kinase regulator activity G-protein beta/gamma-subunit complex binding | Sus scrofa | 3D-structure Acetylation Cell membrane Cytoplasm Direct protein sequencing Membrane Nucleus Phosphoprotein Reference proteome | MQPGATTCTE | MQPGATTCTEDRIQHALERCLHGLSLSRRSTSWSAGLCLNCWSLQELVSRDPGHFLILLEQILQKTREVQEKGTYDLLAPLALLFYSTVLCTPHFPPDSDLLLKAARTYHRFLTWPVPYCSICQELLTFIDAELKAPGISYQRLVRAEQGLSTRSHRSSTVTVLLLNPVEVQAEFLDVADKLSTPGPSPHSAYITLLLHAFQATFGAHCDLSGLHRRLQSKTLAELEAIFTETAEAQELASGIGDAAEARQWLRTKLQAVGEKAGFPGVLDTAKPGKLRTIPIPVARCYTYSWNQDSFDILQEILLKEQELLQPEILDDE... | G protein-coupled receptor signaling pathway phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of MAP kinase activity positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction cytoplasm; membrane; nucleus; phosphatidylinositol 3-kinase complex; phosph... |
activation of innate immune response cellular response to heat cellular response to virus positive regulation of defense response to virus by host positive regulation of interferon-beta production positive regulation of nitric oxide biosynthetic process protein folding protein stabilization regulation of apoptotic proc... | cytoplasm; cytosol; melanosome; mitochondrion; myelin sheath; neuronal cell body; nucleus; perinuclear region of cytoplasm; plasma membrane; protein-containing complex | ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone disordered domain specific binding nitric-oxide synthase regulator activity TPR domain binding unfolded protein binding | Sus scrofa | Acetylation ATP-binding Cell membrane Chaperone Cytoplasm Hydrolase Membrane Mitochondrion Nucleotide-binding Nucleus Phosphoprotein Reference proteome S-nitrosylation Stress response Ubl conjugation | MPEETQTQDQ | MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTND... | activation of innate immune response cellular response to heat cellular response to virus positive regulation of defense response to virus by host positive regulation of interferon-beta production positive regulation of nitric oxide biosynthetic process protein folding protein stabilization regulation of apoptotic proc... |
acetylcholine transport dopamine transport epinephrine transport histamine transport monoatomic ion transport norepinephrine transport organic cation transport prostaglandin transport putrescine transport serotonin transport spermidine transport thiamine transmembrane transport | apical plasma membrane; basal plasma membrane; basolateral plasma membrane | acetylcholine transmembrane transporter activity monoamine transmembrane transporter activity neurotransmitter transmembrane transporter activity organic anion transmembrane transporter activity organic cation transmembrane transporter activity prostaglandin transmembrane transporter activity putrescine transmembrane t... | Sus scrofa | Cell membrane Glycoprotein Ion transport Membrane Reference proteome Transmembrane Transmembrane helix Transport | MLTVDDILEH | MLTVDDILEHTGEFNFFQKQTFFLLALLSAAFTPIYVGIVFLGFIPDHRCRSPGVAELSQRCGWSLAEELNYTVPGPGPAGQAFPRQCRRYEVDWNQSTLGCVDPLAGLAANSSHLPLGPCRYGWVYDTPGSSIVTEFDLVCANSWLLDLFQSAVNVGFFIGSVGIGYIADRFGRKLCLLLTILINAVSGVLMAISPTYTWMLVFRLIQGLVSKAGWMIGYILITEFVGLSYRRTVGIFYQVAFTFGLLVLAGVAYALPHWRWLQFTVTLPNFCFLFYYWCVPESPRWLISQNKNAKAMSIIKHIAKKNGKSLPASLQSL... | acetylcholine transport dopamine transport epinephrine transport histamine transport monoatomic ion transport norepinephrine transport organic cation transport prostaglandin transport putrescine transport serotonin transport spermidine transport thiamine transmembrane transport apical plasma membrane; basal plasma memb... |
extrinsic apoptotic signaling pathway in absence of ligand intrinsic apoptotic signaling pathway in response to DNA damage negative regulation of apoptotic process negative regulation of autophagy negative regulation of cellular pH reduction negative regulation of intrinsic apoptotic signaling pathway regulation of mit... | endoplasmic reticulum membrane; membrane; mitochondrial outer membrane; mitochondrion; nuclear membrane | protein heterodimerization activity protein homodimerization activity | Bos taurus | Apoptosis Cytoplasm Endoplasmic reticulum Membrane Mitochondrion Mitochondrion outer membrane Nucleus Phosphoprotein Reference proteome Transmembrane Transmembrane helix Ubl conjugation | MAHAGGTGYD | MAHAGGTGYDNREIVMKYIHYKLSQRGYEWDAGDAGAAPPGAAPAPGILSSQPGRTPAPSRTSPPPPPAAAAGPAPSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLHLTPFTARERFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDSIALWMTEYLNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKALLSLALVGACITLGAYLGHK | extrinsic apoptotic signaling pathway in absence of ligand intrinsic apoptotic signaling pathway in response to DNA damage negative regulation of apoptotic process negative regulation of autophagy negative regulation of cellular pH reduction negative regulation of intrinsic apoptotic signaling pathway regulation of mit... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.