Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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cartilage development intracellular steroid hormone receptor signaling pathway negative regulation of transcription by RNA polymerase II positive regulation of cellular response to insulin stimulus positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of... | cytoplasm; fibrillar center; intercellular bridge; microtubule cytoskeleton; nucleoplasm; nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription repressor activity, RNA polymerase II-specific estrogen response element binding nuclear receptor activity nuclear steroid receptor activity protein domain specific binding RNA po... | Mus musculus | Acetylation Cytoplasm DNA-binding Isopeptide bond Metal-binding Nucleus Phosphoprotein Receptor Reference proteome Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | MSSQVVGIEP | MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVTLASGPAPARCLPGHKEEEDGEGAGSGEQGSGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAPVNALVSHLLVVEPEKLYAMPDPASPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGDLGAALLQLVRRLQALRL... | cartilage development intracellular steroid hormone receptor signaling pathway negative regulation of transcription by RNA polymerase II positive regulation of cellular response to insulin stimulus positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of... |
potassium ion transmembrane transport potassium ion transport regulation of resting membrane potential response to nicotine sodium ion transmembrane transport stabilization of membrane potential | apical plasma membrane; brush border membrane; dendrite; endosome; intracellular membrane-bounded organelle; inward rectifier potassium channel complex; membrane; perikaryon; plasma membrane; potassium channel complex; recycling endosome; synaptic membrane | identical protein binding inward rectifier potassium channel activity outward rectifier potassium channel activity potassium channel activity potassium ion leak channel activity sodium channel activity | Mus musculus | Cell membrane Cell projection Cytoplasmic vesicle Disulfide bond Endosome Glycoprotein Ion channel Ion transport Isopeptide bond Membrane Phosphoprotein Potassium Potassium channel Potassium transport Reference proteome Synapse Transmembrane Transmembrane helix Transport Ubl conjugation | MLQSLAGSSC | MLQSLAGSSCVRLVERHRSAWCFGFLVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHECLSEPQLEQFLGRVLEASNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGIPFTLLFLTAVVQRVTVHVTRRPVLYFHIRWGFSKQVVAIVHAVLLGFVTVSCFFFIPAAVFSVLEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQKFRELYKIGITCYLLLGLIAMLVVLETFCELHELKKFRKMFYVKKDKDEDLVHIMEHDQLSFSSVTEQVAGLKEEQKQSEP... | potassium ion transmembrane transport potassium ion transport regulation of resting membrane potential response to nicotine sodium ion transmembrane transport stabilization of membrane potential apical plasma membrane; brush border membrane; dendrite; endosome; intracellular membrane-bounded organelle; inward rectifier... |
mRNA export from nucleus mRNA processing positive regulation of DNA-templated transcription, elongation regulation of DNA recombination replication fork processing RNA export from nucleus RNA splicing viral mRNA export from host cell nucleus | catalytic step 2 spliceosome; cytoplasm; nuclear speck; nucleus; transcription export complex | C5-methylcytidine-containing RNA reader activity molecular adaptor activity mRNA binding RNA binding RNA folding chaperone single-stranded DNA binding | Mus musculus | 3D-structure Acetylation Alternative splicing Chaperone Citrullination Cytoplasm Methylation mRNA processing mRNA splicing mRNA transport Nucleus Phosphoprotein Reference proteome RNA-binding Spliceosome Transport | MADKMDMSLD | MADKMDMSLDDIIKLNRSQRGGRGGGRGRGRAGSQGGRGGAVQAAARVNRGGGPMRNRPAIARGAAGGGRNRPAPYSRPKQLPDKWQHDLFDSGFGGGAGVETGGKLLVSNLDFGVSDADIQELFAEFGTLKKAAVHYDRSGRSLGTADVHFERKADALKAMKQYNGVPLDGRPMNIQLVTSQIDTQRRPAQSINRGGMTRNRGSGGFGGGGTRRGTRGGSRGRGRGTGRNSKQQLSAEELDAQLDAYNARMDTS | mRNA export from nucleus mRNA processing positive regulation of DNA-templated transcription, elongation regulation of DNA recombination replication fork processing RNA export from nucleus RNA splicing viral mRNA export from host cell nucleus catalytic step 2 spliceosome; cytoplasm; nuclear speck; nucleus; transcription... |
cytokine-mediated signaling pathway positive regulation of connective tissue replacement positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II | cytoplasm; cytosol; fibrillar center; intracellular membrane-bounded organelle; nucleolus; nucleoplasm; nucleus | DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific double-stranded DNA binding metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequenc... | Mus musculus | Activator DNA-binding Metal-binding Nucleus Reference proteome Repeat Transcription Transcription regulation Zinc Zinc-finger | MDVLPMCSIF | MDVLPMCSIFQELQIVHETGYFSALPSLEEYWQQTCLELERYLQSEPCYVSASEIKFDSQEDLWTKFILAREKKEESELKISSSPPEDSLISSSFNYNLETNSLNSDVSSESSDSSEELSPTTKFTSDPIGEVLVNSGNLSSSVISTPPSSPEVNRESSQLWGCGPGDLPSPGKVRSGTSGKSGDKGNGDASPDGRRRVHRCHFNGCRKVYTKSSHLKAHQRTHTGEKPYRCSWEGCEWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL | cytokine-mediated signaling pathway positive regulation of connective tissue replacement positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II cytoplasm; cytosol; fibrillar center; intracellular membrane-bounded organelle; nucleolus; nucleoplasm; nucleus DNA binding ... |
cell cycle cell division clathrin coat assembly clathrin-dependent endocytosis intracellular protein transport | clathrin coat; clathrin coat of coated pit; clathrin coat of trans-Golgi network vesicle; clathrin complex; clathrin vesicle coat; clathrin-coated pit; clathrin-coated vesicle; cytoplasmic vesicle; glutamatergic synapse; plasma membrane; postsynaptic endocytic zone; postsynaptic endocytic zone cytoplasmic component; pr... | clathrin heavy chain binding GTPase binding peptide binding protein-containing complex binding structural molecule activity | Mus musculus | Acetylation Calcium Cell cycle Cell division Coated pit Cytoplasm Cytoplasmic vesicle Cytoskeleton Membrane Mitosis Phosphoprotein Reference proteome | MAELDPFGAP | MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAPGRATRRAAGGPDAVDGVMNGEYYQESNGPTDSYAAISEVDRLQSEPESIRKWREEQTERLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADLIGYVAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLISLKQAPLVH | cell cycle cell division clathrin coat assembly clathrin-dependent endocytosis intracellular protein transport clathrin coat; clathrin coat of coated pit; clathrin coat of trans-Golgi network vesicle; clathrin complex; clathrin vesicle coat; clathrin-coated pit; clathrin-coated vesicle; cytoplasmic vesicle; glutamaterg... |
negative regulation of protein glutathionylation positive regulation of inorganic anion transmembrane transport positive regulation of organic acid transport positive regulation of sodium ion export across plasma membrane potassium ion transport regulation of cardiac muscle cell contraction regulation of cardiac muscle... | apical plasma membrane; caveola; intercalated disc; sarcolemma; sodium:potassium-exchanging ATPase complex; T-tubule | ATPase binding myosin binding sodium channel regulator activity | Rattus norvegicus | Cell membrane Direct protein sequencing Glutathionylation Ion transport Lipoprotein Membrane Palmitate Phosphoprotein Potassium Potassium transport Reference proteome Signal Sodium Sodium transport Sodium/potassium transport Transmembrane Transmembrane helix Transport | MASPGHILIV | MASPGHILIVCVCLLSMASAEAPQEPDPFTYDYHTLRIGGLTIAGILFILGILIILSKRCRCKFNQQQRTGEPDEEEGTFRSSIRRLSTRRR | negative regulation of protein glutathionylation positive regulation of inorganic anion transmembrane transport positive regulation of organic acid transport positive regulation of sodium ion export across plasma membrane potassium ion transport regulation of cardiac muscle cell contraction regulation of cardiac muscle... |
apoptotic DNA fragmentation DNA catabolic process DNA damage response in utero embryonic development mitochondrial DNA catabolic process negative regulation of TOR signaling positive regulation of apoptotic DNA fragmentation positive regulation of apoptotic process positive regulation of autophagy positive regulation o... | mitochondrial inner membrane; mitochondrion; nucleus; perikaryon; perinuclear region of cytoplasm | DNA endonuclease activity DNA nuclease activity magnesium ion binding nucleic acid binding protein homodimerization activity RNA endonuclease activity single-stranded DNA endodeoxyribonuclease activity | Mus musculus | 3D-structure Disulfide bond Endonuclease Hydrolase Magnesium Metal-binding Mitochondrion Nuclease Phosphoprotein Reference proteome Transit peptide | MRALRAGLTL | MRALRAGLTLALGAGLGAAAEHWRRREGKAPGLLGRVPLLPVVAADLPALPGGPAGGTGELAKYGLPGVAQLRSRESYVLSYDPRTRGALWVLEQLRPERLRGDGDRSACDFREDDSVHAYHRATNADYRGSGFDRGHLAAAANHRWSQRAMDDTFYLSNVAPQVPHLNQNAWNNLERYSRSLTRTYQNVYVCTGPLFLPRTEADGKSYVKYQVIGKNHVAVPTHFFKVLILEAAGGQIELRSYVMPNAPVDETIPLERFLVPIESIERASGLLFVPNILARAGNLKAITAGSK | apoptotic DNA fragmentation DNA catabolic process DNA damage response in utero embryonic development mitochondrial DNA catabolic process negative regulation of TOR signaling positive regulation of apoptotic DNA fragmentation positive regulation of apoptotic process positive regulation of autophagy positive regulation o... |
cholesterol homeostasis cholesterol metabolic process circadian rhythm establishment of localization in cell lipid metabolic process lipid transport lipoprotein metabolic process lipoprotein transport low-density lipoprotein particle remodeling phospholipid transport plasma lipoprotein particle assembly protein secreti... | basolateral plasma membrane; brush border membrane; cytosol; endoplasmic reticulum; Golgi apparatus; microvillus membrane; receptor complex; vesicle | apolipoprotein binding ceramide 1-phosphate transfer activity cholesterol transfer activity lipid binding lipid transporter activity phosphatidylcholine transfer activity phosphatidylethanolamine transfer activity phospholipid transfer activity phospholipid transporter activity protein heterodimerization activity prote... | Mus musculus | Alternative promoter usage Cholesterol metabolism Disulfide bond Endoplasmic reticulum Golgi apparatus Lipid metabolism Lipid transport Lipid-binding Reference proteome Signal Steroid metabolism Sterol metabolism Transport | MILLAVLFLC | MILLAVLFLCFFSSYSASVKGHTTGLSLNNERLYKLTYSTEVFLDGGKGKPQDSVGYKISSDVDVVLLWRNPDGDDDQVIQVTITAVNVENAGQQRGEKSIFQGKSTPKIIGKDNLEALQRPMLLHLVRGKVKEFYSYENEPVGIENLKRGLASLFQMQLSSGTTNEVDISGDCKVTYQAQQDKVVKIKALDTCKIERSGFTTANQVLGVSSKATSVTTYKIEDSFVTAVLAEETRAFALNFQQTIAGKIVSKQKLELKTTEAGPRMIPGKQVAGVIKAVDSKYKAIPIVGQVLERVCKGCPSLAEHWKSIRKNLEPENL... | cholesterol homeostasis cholesterol metabolic process circadian rhythm establishment of localization in cell lipid metabolic process lipid transport lipoprotein metabolic process lipoprotein transport low-density lipoprotein particle remodeling phospholipid transport plasma lipoprotein particle assembly protein secreti... |
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib cellular response to exogenous dsRNA cellular response to lipopolysaccharide defense response to bacterium immune response ... | external side of plasma membrane; extracellular space; intracellular membrane-bounded organelle; plasma membrane | natural killer cell lectin-like receptor binding | Mus musculus | Cell membrane Disulfide bond Glycoprotein GPI-anchor Lipoprotein Membrane Reference proteome Signal | MAKAAVTKRH | MAKAAVTKRHHFMIQKLLILLSYGYTNGLDDAHSLRCNLTIKDPTPADPLWYEAKCLVDEILILHLSNINKTMTSGDPGETANATEVGECLTQPLKDLCQKLRNKVSNTKVDTHKTNGYPHLQVTMIYLQSQGQIPSATWEFNISDSYFFTFYTENMSWRSANDESGVIMNKWKDDGEFVKRLKFLIPECRQEVDEFLKQPKEKPRSTSRSPSITQLTSTSPLPPPSHSTSKKGFISVGLIFISLLFAFAFAM | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib cellular response to exogenous dsRNA cellular response to lipopolysaccharide defense response to bacterium immune response ... |
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib cellular response to exogenous dsRNA cellular response to lipopolysaccharide defense response to bacterium immune response ... | external side of plasma membrane; extracellular space; intracellular membrane-bounded organelle; plasma membrane | natural killer cell lectin-like receptor binding | Mus musculus | 3D-structure Cell membrane Disulfide bond Glycoprotein GPI-anchor Lipoprotein Membrane Reference proteome Signal | MAKAAVTKRH | MAKAAVTKRHHFMIQKLLILLSYGYTNGLDDAHSLRCNLTIKDPTPADPLWYEAKCFVGEILILHLSNINKTMTSGDPGETANATEVKKCLTQPLKNLCQKLRNKVSNTKVDTHKTNGYPHLQVTMIYPQSQGRTPSATWEFNISDSYFFTFYTENMSWRSANDESGVIMNKWKDDGEFVKQLKFLIHECSQKMDEFLKQSKEKPRSTSRSPSITQLTSTSPLPPPSHSTSKKGFISVGLIFISLLFAFAFAM | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib cellular response to exogenous dsRNA cellular response to lipopolysaccharide defense response to bacterium immune response ... |
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib cellular response to exogenous dsRNA cellular response to lipopolysaccharide defense response to bacterium immune response ... | external side of plasma membrane; extracellular space; intracellular membrane-bounded organelle; plasma membrane | natural killer cell lectin-like receptor binding | Mus musculus | 3D-structure Cell membrane Disulfide bond Glycoprotein GPI-anchor Lipoprotein Membrane Reference proteome Signal | MAKAAVTKRH | MAKAAVTKRHHFMIQKLLILLSYGYTNGLDDAHSLRCNLTIKAPTPADPLWYEAKCLVDEILILHLSNINKTMTSGDPGETANATEVGECLTQPVNDLCQKLRDKVSNTKVDTHKTNGYPHLQVTMIYPQSQGQTPSATWEFNISDSYFFTFYTENMSWRSANDESGVIMNKWNDDGDLVQRLKYFIPECRQKIDEFLKQSKEKPRSTSRSPSITQLTSTSPLPPPSHSTSKKGFISVGLIFISLLFAFAFAM | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib cellular response to exogenous dsRNA cellular response to lipopolysaccharide defense response to bacterium immune response ... |
extrinsic apoptotic signaling pathway in absence of ligand intracellular signal transduction protein phosphorylation regulation of translational initiation response to salt stress | cytoplasm; nucleoplasm; nucleus | ATP binding calcium-dependent protein serine/threonine kinase activity calmodulin binding calmodulin-dependent protein kinase activity metal ion binding protein serine kinase activity protein serine/threonine kinase activity | Mus musculus | ATP-binding Kinase Magnesium Metal-binding Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase Translation regulation | MVSSQKLEKP | MVSSQKLEKPIEMGSSEPLPIVDSDKRRKKKRKTRATDSLPGKFEDVYQLTSELLGEGAYAKVQGAVNLQSGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNRNILELIEFFEDDTRFYLVFEKLQGGSILAHIQKRKHFNEREASRVVRDVATALDFLHTKGIAHRDLKPENILCESPEKVSPVKICDFDLGSGVKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFRDEATFYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRMCQNKLFESIQEGKYEFPDKDWAHISNEAKDLISKLLVRDAKQ... | extrinsic apoptotic signaling pathway in absence of ligand intracellular signal transduction protein phosphorylation regulation of translational initiation response to salt stress cytoplasm; nucleoplasm; nucleus ATP binding calcium-dependent protein serine/threonine kinase activity calmodulin binding calmodulin-depende... |
negative regulation of polyamine transmembrane transport polyamine biosynthetic process polyamine metabolic process positive regulation of intracellular protein transport positive regulation of protein catabolic process | cytoplasm; nucleus | ornithine decarboxylase inhibitor activity | Mus musculus | Nucleus Phosphoprotein Polyamine biosynthesis Reference proteome Ribosomal frameshifting | MINTQDSSIL | MINTQDSSILPLSKCPQLQCCRHIVPGPLWCSDAPHPLSKIPGGRGGGRDPSLSALIYKDEKLTVTQDLPVNDGKPHIVHFQYEVTEVKVSSWDAVLSSQSLFVEIPDGLLADGSKEGLLALLEFAEEKMKVNYVFICFRKGREDRAPLLKTFSFLGFEIVRPGHPCVPSRPDVMFMVYPLDQNLSDED | negative regulation of polyamine transmembrane transport polyamine biosynthetic process polyamine metabolic process positive regulation of intracellular protein transport positive regulation of protein catabolic process cytoplasm; nucleus ornithine decarboxylase inhibitor activity Mus musculus Nucleus Phosphoprotein Po... |
negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II nucleocytoplasmic transport positive regulation of glycolytic process positive regulation of lipid biosynthetic process positive regulation of transcription by RNA polymerase II positive regulation of transcript... | cytoplasm; cytosol; nuclear membrane; nucleoplasm; nucleus; RNA polymerase II transcription regulator complex | DNA binding DNA-binding transcription factor activity DNA-binding transcription repressor activity, RNA polymerase II-specific protein heterodimerization activity protein homodimerization activity RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II-specific DNA-binding tran... | Mus musculus | Activator Alternative splicing Cytoplasm DNA-binding Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation | MTEPGASPED | MTEPGASPEDPWVKASFADAHAGEGRAGRARARRGSGRRGAPQLSPESPLLSGARGCREDSSHPACAKVEYAYSDNSLDPGLFVESTHKGSVVSRANSIGSTSASSVPNTDDEDSDYQQEAYKESYKDRRRRAHTQAEQKRRDAIKRGYDDLQTIVPTCQQQDFSIGSQKLSKAIVLQKTIDYIQFLHKEKKKQEEEVSTLRKDVTALKIMKVNYEQIVKAHQDNPHEGEDQVSDQVKFNVFQGIMDSLFQSFNASISVASFQELSACVFSWIEEHCEPQTLREIVIGVLHQLKNQLY | negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II nucleocytoplasmic transport positive regulation of glycolytic process positive regulation of lipid biosynthetic process positive regulation of transcription by RNA polymerase II positive regulation of transcript... |
adaptive immune response amino acid catabolic process L-phenylalanine catabolic process negative regulation of T cell activation negative regulation of T cell mediated immune response to tumor cell negative regulation of T cell proliferation positive regulation of regulatory T cell differentiation positive regulation o... | acrosomal vesicle; extracellular region; immunological synapse; lysosome; sperm midpiece | L-amino-acid oxidase activity L-phenylalaine oxidase activity polyamine oxidase activity | Mus spretus | Adaptive immunity Cytoplasmic vesicle FAD Flavoprotein Glycoprotein Immunity Lysosome Oxidoreductase Secreted | AFKDLKALGC | AFKDLKALGCKKAMNKFNKHTLLEYLLEEGNLSRPAVQLLGDVMSE | adaptive immune response amino acid catabolic process L-phenylalanine catabolic process negative regulation of T cell activation negative regulation of T cell mediated immune response to tumor cell negative regulation of T cell proliferation positive regulation of regulatory T cell differentiation positive regulation o... |
dephosphorylation ERBB2 signaling pathway in utero embryonic development negative regulation of epithelial cell migration negative regulation of ERK1 and ERK2 cascade nervous system development neuron differentiation signal transduction | cell junction; cytosol; plasma membrane | protein kinase binding protein tyrosine phosphatase activity | Rattus norvegicus | Alternative splicing Cell membrane Cytoplasm Glycoprotein Hydrolase Membrane Phosphoprotein Protein phosphatase Proteoglycan Receptor Reference proteome Signal Transmembrane Transmembrane helix | MRRAVGFPAL | MRRAVGFPALCLLLNLHAAGCFSRNNDHFLAIRQKKSWKPMFIYDHSQDIKKSLDIAQEAYKHNYPAPSEVQISKRHQIVDSAFPRPAYDPSLNLLAASGQDLEIENLPIPAANVIVVTLQMDIDKLNITLLRIFRQGVAAALGLLPQQVHINRLIEKKSQIELFVSPGNRKPGEPQALQAEEVLRSLNVDVLRQSLPQFGSIDVSPEKNVLQGQHEADKIWSKEGFYAVVIFLSIFIIIVTCLMIIYRLKERLQLSFRQDKEKNQEIHLSPIALQQAQSEAKAAHSMVQPDQAPKVLNVVVDPQGQCTPEIRNTASTSV... | dephosphorylation ERBB2 signaling pathway in utero embryonic development negative regulation of epithelial cell migration negative regulation of ERK1 and ERK2 cascade nervous system development neuron differentiation signal transduction cell junction; cytosol; plasma membrane protein kinase binding protein tyrosine pho... |
calcium-ion regulated exocytosis cellular response to calcium ion chemical synaptic transmission positive regulation of calcium ion-dependent exocytosis presynaptic dense core vesicle exocytosis regulation of calcium ion-dependent exocytosis regulation of dopamine secretion sensory perception of smell | exocytic vesicle; glutamatergic synapse; plasma membrane; presynapse; synaptic vesicle membrane | calcium ion binding calcium-dependent phospholipid binding clathrin binding identical protein binding phosphatidylinositol-4,5-bisphosphate binding phosphatidylserine binding protein heterodimerization activity protein homodimerization activity SNARE binding syntaxin binding | Rattus norvegicus | Calcium Cytoplasmic vesicle Disulfide bond Exocytosis Membrane Metal-binding Phosphoprotein Reference proteome Repeat Transmembrane Transmembrane helix | MSFRKEDGVS | MSFRKEDGVSSLCQKALHIITELCFAGQVEWDKCSGIFPADRSGQGGGGTDISVSLLAVVVSFCGLALLVVSLFVFWKLCWPCWKSKLVAPNVSTLPQSISSAPTEVFETEEKKEVEENEKPAPKAIEPAIKISHTSPDIPAEVQTALKEHLIKHARVQRQTTDPTSSSRHNSFRRHLPRQMNVSSVDFSMGTEPVLQRGETRTSIGRIKPELYKQKSVDSEGNRKDDVKTCGKLNFALQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKIYLLPDRKKKFQTRVHRKTLNPLFDELFQFPVVYDQLSNRKLHFSIYD... | calcium-ion regulated exocytosis cellular response to calcium ion chemical synaptic transmission positive regulation of calcium ion-dependent exocytosis presynaptic dense core vesicle exocytosis regulation of calcium ion-dependent exocytosis regulation of dopamine secretion sensory perception of smell exocytic vesicle;... |
chromatin organization convergent extension involved in axis elongation DNA repair embryo implantation embryonic placenta morphogenesis epithelial to mesenchymal transition genomic imprinting in utero embryonic development innate immune response negative regulation of DNA demethylation negative regulation of DNA-templa... | chromatin; euchromatin; heterochromatin; nucleoplasm; nucleus; protein-containing complex; RNA polymerase II transcription regulator complex | chromatin binding chromo shadow domain binding DNA binding Krueppel-associated box domain binding promoter-specific chromatin binding protein kinase activity SUMO transferase activity transcription coactivator activity transcription corepressor activity ubiquitin protein ligase activity ubiquitin protein ligase binding... | Rattus norvegicus | Acetylation ADP-ribosylation Bromodomain Chromatin regulator Citrullination Coiled coil Isopeptide bond Metal-binding Nucleus Phosphoprotein Reference proteome Repeat Repressor Transcription Transcription regulation Transferase Ubl conjugation Ubl conjugation pathway Zinc Zinc-finger | MAASAAAATA | MAASAAAATAAASAATAASAASGSPGSGEGSAGGEKRPAASSAAAASASASSPAGGGGEAQELLEHCGVCRERLRPERDPRLLPCLHSACSACLGPATPAAANNSGDGGSAGDGAMVDCPVCKQQCYSKDIVENYFMRDSGSKASSDSQDANQCCTSCEDNAPATSYCVECSEPLCETCVEAHQRVKYTKDHTVRSTGPAKTRDGERTVYCNVHKHEPLVLFCESCDTLTCRDCQLNAHKDHQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKNTKEVRSSIRQVSDVQKRVQVDVKMAILQIMKELNKRGRVLVNDAQ... | chromatin organization convergent extension involved in axis elongation DNA repair embryo implantation embryonic placenta morphogenesis epithelial to mesenchymal transition genomic imprinting in utero embryonic development innate immune response negative regulation of DNA demethylation negative regulation of DNA-templa... |
activated T cell proliferation axon guidance ephrin receptor signaling pathway positive regulation of T cell costimulation T cell mediated immunity type IV hypersensitivity | cell surface; dendrite; extracellular region; plasma membrane | ATP binding transmembrane-ephrin receptor activity | Mus musculus | Alternative splicing ATP-binding Cell membrane Glycoprotein Membrane Nucleotide-binding Receptor Reference proteome Repeat Secreted Signal Transmembrane Transmembrane helix | MATEGTTGSG | MATEGTTGSGSRVVAGMVCSLWLLVLGSSVLALEEVLLDTTGETSEIGWLTYPPGGWDEVSVLDDQRRLTRTFEACHVAGLPPGSGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVSGGTCRETFTLYYRQADEPDGPDSIAAWHLKRWTKVDTIAADESFPASSSSSSWAVGPHRTGQRVGLQLNVKERSFGPLTQRGFYVAFQDTGACLALVAVKLFSYTCPSVLRAFASFPETQASGAGGASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGRWMVAVGGCRCQPGHQPARGDKLCQACPEGSYKAL... | activated T cell proliferation axon guidance ephrin receptor signaling pathway positive regulation of T cell costimulation T cell mediated immunity type IV hypersensitivity cell surface; dendrite; extracellular region; plasma membrane ATP binding transmembrane-ephrin receptor activity Mus musculus Alternative splicing ... |
extracellular matrix assembly extracellular polysaccharide biosynthetic process hyaluronan biosynthetic process positive regulation of DNA-templated transcription positive regulation of hyaluranon cable assembly | cytoplasm; cytoplasmic vesicle; Golgi apparatus; Golgi membrane; hyaluranon cable; nucleus; plasma membrane | hyaluronan synthase activity identical protein binding | Mus musculus | Cell membrane Cytoplasmic vesicle Glycoprotein Glycosyltransferase Golgi apparatus Membrane Reference proteome Transferase Transmembrane Transmembrane helix | MPVQLTTALR | MPVQLTTALRVVGTSLFALVVLGGILAAYVTGYQFIHTEKHYLSFGLYGAILGLHLLIQSLFAFLEHRRMRRAGRPLKLHCSQRPRSVALCIAAYQEDPEYLRKCLRSAQRIAFPNLKVVMVVDGNRQEDTYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGETEASLQEGMERVRAVVWASTFSCIMQKWGGKREVMYTAFKALGNSVDYIQVCDSDTVLDPACTIEMLRVLEEDPQVGGVGGDVQILNKYDSWISFLSSVRYWMAFNVERACQSYFGCVQCISGPLGMYRNSLLQQFLEDWYHQKFLGSKCSFGDDRH... | extracellular matrix assembly extracellular polysaccharide biosynthetic process hyaluronan biosynthetic process positive regulation of DNA-templated transcription positive regulation of hyaluranon cable assembly cytoplasm; cytoplasmic vesicle; Golgi apparatus; Golgi membrane; hyaluranon cable; nucleus; plasma membrane ... |
abducens nerve formation anatomical structure formation involved in morphogenesis anatomical structure morphogenesis anterior/posterior pattern specification artery development artery morphogenesis cellular response to ethanol cellular response to retinoic acid central nervous system neuron differentiation cochlea deve... | nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific identical protein binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA binding | Rattus norvegicus | Developmental protein DNA-binding Glycoprotein Homeobox Nucleus Reference proteome Transcription Transcription regulation | MDNARLNSFL | MDNARLNSFLEYPILGSGDSGTCSARVYSSDHGITTFQSCAVSANSCGGDDRFLGGRGVQITSPHHHHHHHHHPQPATYQTSGNLGVSYSHSSCGPSYGAQNFSAPYGPYGLNQEADVSGGYPPCAPAVYSGNLSSPMVQHHHHHQGYAGGTVGSPQYIHHSYGQEHQSLALATYNNSLSPLHASHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGEYGYVGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARSEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPMSPATPPGSDEKTEESSEKSSSSPSAPS... | abducens nerve formation anatomical structure formation involved in morphogenesis anatomical structure morphogenesis anterior/posterior pattern specification artery development artery morphogenesis cellular response to ethanol cellular response to retinoic acid central nervous system neuron differentiation cochlea deve... |
N-terminal protein amino acid modification peptidyl-methionine modification protein processing | cytoplasm; cytosol; plasma membrane | aminopeptidase activity initiator methionyl aminopeptidase activity metal ion binding metalloaminopeptidase activity metalloexopeptidase activity | Mus musculus | Acetylation Aminopeptidase Cytoplasm Direct protein sequencing Glycoprotein Hydrolase Metal-binding Phosphoprotein Protease Reference proteome | MAGVEQAASF | MAGVEQAASFGGHLNGDLDPDDREEGTSSTAEEAAKKKRRKKKKGKGAVSAVQQELDKESGALVDEVAKQLESQALEEKERDDDDEDGDGDADGATGKKKKKKKKKRGPKVQTDPPSVPICDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDILLTAVKDATNTGIKCAGIDVRLCDVGEAIQEVMESYEVEIDGKTY... | N-terminal protein amino acid modification peptidyl-methionine modification protein processing cytoplasm; cytosol; plasma membrane aminopeptidase activity initiator methionyl aminopeptidase activity metal ion binding metalloaminopeptidase activity metalloexopeptidase activity Mus musculus Acetylation Aminopeptidase Cyt... |
positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II | nucleus; transcription regulator complex | chromatin binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA bindi... | Mus musculus | Activator DNA-binding Nucleus Reference proteome Transcription Transcription regulation | MDPRETTDPS | MDPRETTDPSLPPGPLTHLSLPDSSEVRLQSDGPSLLGSWTRSPPEHAIILREGVRTCLQQRCEQTVWILHAKVAQKSYGNEKRFFCPPPCVYLAGPGWRVKPMQDQALQSAETGPTVCGYMGLDGASGSAPETQKLNFEEQPDSREFGCAKTLYISDADKRKHFRLVLRLVLRGGQELGTFHSRLIKVISKPSQKKQSLKNTDLCISSGSKVSLFNRLRSQTVSTRYLSVEDGAFVASARQWAAFTLHLADGHCSQGDFPPQEGYIRYGSLVQLVCTVTGITLPPMIIRKVAKQCALLDVDEPISQLHKCAFQFPSDTP... | positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II nucleus; transcription regulator complex chromatin binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specif... |
blood coagulation G protein-coupled receptor signaling pathway ligand-gated ion channel signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of insulin secretion positive regulation of Rho protein signal transduction | apical plasma membrane; protein-containing complex | G protein-coupled receptor activity proteinase-activated receptor activity receptor ligand activity thrombin-activated receptor activity | Mus musculus | 3D-structure Blood coagulation Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Hemostasis Membrane Receptor Reference proteome Signal Transducer Transmembrane Transmembrane helix | MKILILVAAG | MKILILVAAGLLFLPVTVCQSGINVSDNSAKPTLTIKSFNGGPQNTFEEFPLSDIEGWTGATTTIKAECPEDSISTLHVNNATIGYLRSSLSTQVIPAIYILLFVVGVPANIVTLWKLSLRTKSISLVIFHTNLAIADLLFCVTLPFKIAYHLNGNNWVFGEVTCRITTVVFYGNMYCAILILTCMGINRYLATAHPFTYQKLPKRSFSMLMCGMVWVMVFLYMLPFVILKQEYHLVHSEITTCHDVVDACESPSSFRFYYFVSLAFFGFLIPFVIIIFCYTTLIHKLKSKDRIWLGYIKAVLLILVIFTICFAPTNIIL... | blood coagulation G protein-coupled receptor signaling pathway ligand-gated ion channel signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of insulin secretion positive regulation of Rho protein signal transduction apical plasma membrane; protein-containing com... |
antimicrobial humoral immune response mediated by antimicrobial peptide blood coagulation inflammatory response killing of cells of another organism negative regulation of blood coagulation negative regulation of cell adhesion negative regulation of proteolysis positive regulation of cytosolic calcium ion concentration... | collagen-containing extracellular matrix; extracellular region; extracellular space; perikaryon | cysteine-type endopeptidase inhibitor activity hormone activity protease binding signaling receptor binding | Mus musculus | Alternative splicing Blood coagulation Direct protein sequencing Disulfide bond Glycoprotein Hemostasis Inflammatory response Phosphoprotein Protease inhibitor Reference proteome Repeat Secreted Signal Thiol protease inhibitor Vasoactive Vasodilator | MKLITTLLLC | MKLITTLLLCSGLLLTLTQGEEAQEIDCNDEAVFQAVDFSLKQFNPGVKSGNQYMLHRVIEGTKTDGSPTFYSFKYLIKEGNCSAQSGLAWQDCDFKDAEEAATGECTATVGKRENEFFIVTQTCKIAPSKAPILKAYFPCIGCVHAISTDSPDLEPVLKHSIEHFNNNTDHSHLFTLRKVKSAHRQVVAGLNFDITYTIVQTNCSKERFPSLHGDCVALPNGDDGECRGNLFMDINNKIANFSQSCTLYSGDDLVEALPKPCPGCPRDIPVDSPELKEVLGHSIAQLNAENDHPFYYKIDTVKKATSQVVAGTKYVIEF... | antimicrobial humoral immune response mediated by antimicrobial peptide blood coagulation inflammatory response killing of cells of another organism negative regulation of blood coagulation negative regulation of cell adhesion negative regulation of proteolysis positive regulation of cytosolic calcium ion concentration... |
cytoskeleton organization establishment of mitochondrion localization intracellular signal transduction microtubule cytoskeleton organization negative regulation of epithelial to mesenchymal transition negative regulation of gene expression neuron migration positive regulation of gene expression protein phosphorylation... | cytoplasm; cytoskeleton; dendrite; plasma membrane | ATP binding magnesium ion binding phosphatidic acid binding phosphatidylinositol-4,5-bisphosphate binding phosphatidylserine binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity tau-protein kinase activity | Rattus norvegicus | ATP-binding Cell membrane Cell projection Cytoplasm Cytoskeleton Kinase Lipid-binding Magnesium Membrane Metal-binding Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase Wnt signaling pathway | MSARTPLPTV | MSARTPLPTVNERDTENHTSVDGYTETHIPPTKSSSRQNIPRCRNSITSATDEQPHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKCIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRVPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVGHEEEEL... | cytoskeleton organization establishment of mitochondrion localization intracellular signal transduction microtubule cytoskeleton organization negative regulation of epithelial to mesenchymal transition negative regulation of gene expression neuron migration positive regulation of gene expression protein phosphorylation... |
axon development establishment of cell polarity establishment or maintenance of cell polarity regulating cell shape establishment or maintenance of epithelial cell apical/basal polarity intracellular signal transduction microtubule cytoskeleton organization neuron migration peptidyl-serine phosphorylation positive regu... | actin filament; basal cortex; cytoplasm; dendrite; glutamatergic synapse; lateral plasma membrane; membrane; microtubule bundle; nucleus; plasma membrane; postsynapse | ATP binding lipid binding magnesium ion binding molecular function activator activity protein serine kinase activity protein serine/threonine kinase activity tau protein binding tau-protein kinase activity | Rattus norvegicus | 3D-structure ATP-binding Cell membrane Cell projection Cytoplasm Cytoskeleton Developmental protein Differentiation Kinase Lipid-binding Magnesium Membrane Metal-binding Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase Wnt signaling pathway | MSSARTPLPT | MSSARTPLPTLNERDTEQPTLGHLDSKPSSKSNMLRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPL... | axon development establishment of cell polarity establishment or maintenance of cell polarity regulating cell shape establishment or maintenance of epithelial cell apical/basal polarity intracellular signal transduction microtubule cytoskeleton organization neuron migration peptidyl-serine phosphorylation positive regu... |
axon guidance cell migration cellular response to follicle-stimulating hormone stimulus cellular response to retinoic acid endocardial cushion development ephrin receptor signaling pathway fasciculation of motor neuron axon fasciculation of sensory neuron axon fever generation negative regulation of endocytosis negativ... | dendrite; early endosome; GABA-ergic synapse; plasma membrane; presynapse | ATP binding ephrin receptor activity GPI-linked ephrin receptor activity growth factor binding transmembrane-ephrin receptor activity | Rattus norvegicus | ATP-binding Cell membrane Glycoprotein Kinase Membrane Nucleotide-binding Phosphoprotein Receptor Reference proteome Repeat Signal Transferase Transmembrane Transmembrane helix Tyrosine-protein kinase | MDCHLSILIL | MDCHLSILILFGCCVLSCSRELSPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVKFLEHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNSKEEDPPRMYCSTEGEWLVPIGKCTCNAGYEERGFICQACRPGFYKALDGVAKCTKCPPHSSTQEDGSMNCRCENNYFRAEKDPPSM... | axon guidance cell migration cellular response to follicle-stimulating hormone stimulus cellular response to retinoic acid endocardial cushion development ephrin receptor signaling pathway fasciculation of motor neuron axon fasciculation of sensory neuron axon fever generation negative regulation of endocytosis negativ... |
cartilage condensation myotube differentiation negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II skeletal muscle cell differentiation transcription by RNA polymerase II | actin cytoskeleton; cytosol; Golgi apparatus; nucleoplasm; nucleus; transcription regulator complex | chromatin binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific DNA bin... | Mus musculus | DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation | MHCHAELRLS | MHCHAELRLSSPGQLKAARRRYKTFMIDEILSKETCDYFEKLSLYSVCPSLVVRPKPLHSCTGSPSLRAYPLLSVITRQPTVISHLVPTGSGLTPVLTRHPVAAAEAAAAAAETPGGEALASSESETEQPTPRQKKPRRSRTIFTELQLMGLEKKFQKQKYLSTPDRLDLAQSLGLTQLQVKTWYQNRRMKWKKMVLKGGQEAPTKPKGRPKKNSIPTSEEIEAEEKMNSQAQSQELLESSERQEEPCDTQEPKACLVPLEVAEPIHQPQELSEASSEPPPLS | cartilage condensation myotube differentiation negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II skeletal muscle cell differentiation transcription by RNA polymerase II actin cytoskeleton; cytosol; Golgi a... |
defense response negative regulation of angiogenesis negative regulation of lymphangiogenesis | cytoplasmic vesicle; extracellular space | cysteine-type endopeptidase inhibitor activity | Mus musculus | Direct protein sequencing Disulfide bond Protease inhibitor Reference proteome Secreted Signal Thiol protease inhibitor Tumor suppressor | MAGLWKTFVL | MAGLWKTFVLVVALAVVSCEALRQLRYEEIVDRAIEAYNQGRQGRPLFRLLSATPPSSQNPATNIPLQFRIKETECTSTQERQPKDCDFLEDGEERNCTGKFFRRRQSTSLTLTCDRDCSREDTQETSFNDKQDVSEKEKFEDVPPHIRNIYEDAKYDIIGNILKNF | defense response negative regulation of angiogenesis negative regulation of lymphangiogenesis cytoplasmic vesicle; extracellular space cysteine-type endopeptidase inhibitor activity Mus musculus Direct protein sequencing Disulfide bond Protease inhibitor Reference proteome Secreted Signal Thiol protease inhibitor Tumor... |
cell population proliferation DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator DNA repair G2/M transition of mitotic cell cycle liver development negative regulation of DNA-templated transcription negative regulation of stress-activated MAPK cascade negativ... | nucleus | DNA binding DNA-binding transcription factor activity protein kinase binding RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific DNA binding transcription cis-regulatory region binding | Mus musculus | Activator Cell cycle DNA damage DNA repair DNA-binding Isopeptide bond Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Ubl conjugation | MRTSPRRPLI | MRTSPRRPLILKRRRLPLPVQNAPSETSEEEAKRSPAQPEPAPAQASQEVAESSSCKFPAGIKIINHPTTPNTQVVAIPSNADIQSIITALTAKGKESGTSGPNRFILISSGGPSSHPSQPQAHSSRDSKRAEVITETLGPKPAAKGVPVPKPPGAPPRQRQESYAGGEAAGCTLDNSLTNIQWLGKMSSDGLGPCSVKQELEEKENCHLEQNRVKVEEPSGVSTSWQDSVSERPPYSYMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETSANGKVSFWTIHPSANRHLTLDQ... | cell population proliferation DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator DNA repair G2/M transition of mitotic cell cycle liver development negative regulation of DNA-templated transcription negative regulation of stress-activated MAPK cascade negativ... |
acetylcholine transport bicellular tight junction assembly centrosome cycle maintenance of protein location in nucleus negative regulation of GTPase activity positive regulation of cell-substrate adhesion positive regulation of microtubule polymerization protein folding regulation of aerobic respiration regulation of g... | centrosome; cytoplasm; lateral plasma membrane; microtubule cytoskeleton; mitochondrial intermembrane space; mitochondrion; nucleus | GDP binding GTP binding GTPase activity | Rattus norvegicus | Cell cycle Cytoplasm Cytoskeleton GTP-binding Isopeptide bond Lipoprotein Mitochondrion Myristate Nucleotide-binding Nucleus Phosphoprotein Reference proteome Ubl conjugation | MGLLTILKKM | MGLLTILKKMKQKERDVRLLMLGLDNAGKTTILKKFNGEDVDTISPTLGFNIKTLEHRGFKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQRMQDCQRELQSLLVEERLAGATLLIFANKQDLPGALSCNAIQEALELDSIRSHHWRIQGCSAVTGEDLLPGIDWLLDDISSRVFTAD | acetylcholine transport bicellular tight junction assembly centrosome cycle maintenance of protein location in nucleus negative regulation of GTPase activity positive regulation of cell-substrate adhesion positive regulation of microtubule polymerization protein folding regulation of aerobic respiration regulation of g... |
ductus arteriosus closure female pregnancy kidney development negative regulation of cell cycle ovulation parturition positive regulation of apoptotic process positive regulation of vascular associated smooth muscle cell proliferation prostaglandin metabolic process regulation of prostaglandin catabolic process respons... | basolateral plasma membrane; cytoplasm; cytosol; extracellular space; nucleoplasm | 15-hydroxyprostaglandin dehydrogenase (NAD+) activity identical protein binding NAD binding NAD+ binding oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor prostaglandin E receptor activity | Rattus norvegicus | Cytoplasm Fatty acid metabolism Lipid metabolism NAD Oxidoreductase Prostaglandin metabolism Reference proteome Tumor suppressor | MHVNGKVALV | MHVNGKVALVTGAAQGIGKAFTEALLLHGAKVALVDWNLETGVKCKAALDEQFEPQKTLFIQCDVADQKQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEQTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINISSIAGLMPVAQQPVYCASKHGIIGFTRSAAMAANLMKSGVRLNVICPGFVKTPILESIEKEENMGQYIEYTDQIKAMMKFYGILDPSAIANGLINLIEDDALNGAIMKITASKGIHFQDYDLFPSFSKAP | ductus arteriosus closure female pregnancy kidney development negative regulation of cell cycle ovulation parturition positive regulation of apoptotic process positive regulation of vascular associated smooth muscle cell proliferation prostaglandin metabolic process regulation of prostaglandin catabolic process respons... |
bile acid and bile salt transport bile acid signaling pathway cellular response to xenobiotic stimulus regulation of bile acid secretion response to estrogen response to ethanol response to nutrient levels response to organic cyclic compound | basolateral plasma membrane; membrane | bile acid transmembrane transporter activity bile acid:sodium symporter activity | Mus musculus | Alternative splicing Cell membrane Glycoprotein Ion transport Lipid transport Membrane Phosphoprotein Reference proteome Sodium Sodium transport Symport Transmembrane Transmembrane helix Transport | MEAHNVSAPF | MEAHNVSAPFNFSLPPGFGHRATDTALSVILVVMLLLIMLSLGCTMEFSKIKAHFWKPKGVIIAIVAQYGIMPLSAFLLGKVFHLTSIEALAILICGCSPGGNLSNLFTLAMKGDMNLSIVMTTCSSFTALGMMPLLLYIYSKGIYDGDLKDKVPYKGIMLSLVMVLIPCAIGIFLKSKRPHYVPYVLKAGMIITFSLSVAVTVLSVINVGNSIMFVMTPHLLATSSLMPFTGFLMGYILSALFRLNPSCRRTISMETGFQNVQLCSTILNVTFPPEVIGPLFFFPLLYMIFQLAEGLLFIIIFRCYLKIKPQKDQTKIT... | bile acid and bile salt transport bile acid signaling pathway cellular response to xenobiotic stimulus regulation of bile acid secretion response to estrogen response to ethanol response to nutrient levels response to organic cyclic compound basolateral plasma membrane; membrane bile acid transmembrane transporter acti... |
calcium-mediated signaling cell chemotaxis immune response inflammatory response positive regulation of cytosolic calcium ion concentration signal transduction | actin filament; cytosol; early endosome; external side of plasma membrane; intracellular membrane-bounded organelle; nuclear membrane; nucleoplasm; plasma membrane; recycling endosome | C-C chemokine binding C-C chemokine receptor activity chemokine receptor activity scavenger receptor activity | Mus musculus | Cell membrane Disulfide bond Endosome G-protein coupled receptor Glycoprotein Inflammatory response Membrane Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MPTVASPLPL | MPTVASPLPLTTVGSENSSSIYDYDYLDDMTILVCRKDEVLSFGRVFLPVVYSLIFVLGLAGNLLLLVVLLHSAPRRRTMELYLLNLAVSNLLFVVTMPFWAISVAWHWVFGSFLCKVISTLYSINFYCGIFFITCMSLDKYLEIVHAQPLHRPKAQFRNLLLIVMVWITSLAISVPEMVFVQIHQTLDGVWHCYADFGGHATIWKLYLRFQLNLLGFLLPLLAMIFFYSRIGCVLVRLRPPGQGRALRMAAALVIVFFMLWFPYNLTLFLHSLLDLHVFGNCEISHRLDYTLQVTESLAFSHCCFTPVLYAFCSHRFRR... | calcium-mediated signaling cell chemotaxis immune response inflammatory response positive regulation of cytosolic calcium ion concentration signal transduction actin filament; cytosol; early endosome; external side of plasma membrane; intracellular membrane-bounded organelle; nuclear membrane; nucleoplasm; plasma membr... |
bleb assembly cell redox homeostasis cellular oxidant detoxification glycerophospholipid catabolic process hydrogen peroxide catabolic process positive regulation of mRNA splicing, via spliceosome response to oxidative stress response to reactive oxygen species | cytoplasm; cytosol; lysosome; mitochondrion; nucleus; perinuclear region of cytoplasm | 1-acylglycerophosphocholine O-acyltransferase activity calcium-independent phospholipase A2 activity glutathione peroxidase activity identical protein binding peroxidase activity peroxiredoxin activity phospholipase A2 activity ubiquitin protein ligase binding | Mus musculus | Acetylation Antioxidant Cytoplasm Direct protein sequencing Hydrolase Lipid degradation Lipid metabolism Lysosome Multifunctional enzyme Oxidoreductase Peroxidase Phosphoprotein Redox-active center Reference proteome Transferase | MPGGLLLGDE | MPGGLLLGDEAPNFEANTTIGRIRFHDFLGDSWGILFSHPRDFTPVCTTELGRAAKLAPEFAKRNVKLIALSIDSVEDHLAWSKDINAYNGETPTEKLPFPIIDDKGRDLAILLGMLDPVEKDDNNMPVTARVVFIFGPDKKLKLSILYPATTGRNFDEILRVVDSLQLTGTKPVATPVDWKKGESVMVVPTLSEEEAKQCFPKGVFTKELPSGKKYLRYTPQP | bleb assembly cell redox homeostasis cellular oxidant detoxification glycerophospholipid catabolic process hydrogen peroxide catabolic process positive regulation of mRNA splicing, via spliceosome response to oxidative stress response to reactive oxygen species cytoplasm; cytosol; lysosome; mitochondrion; nucleus; peri... |
antiviral innate immune response apoptotic process negative regulation of cardiac muscle hypertrophy negative regulation of protein dephosphorylation negative regulation of protein import into nucleus | endoplasmic reticulum; lipid droplet; membrane; mitochondrial crista; mitochondrial outer membrane; mitochondrion; neuromuscular junction; postsynaptic membrane; postsynaptic specialization, intracellular component | beta-tubulin binding microtubule binding molecular adaptor activity protein kinase A regulatory subunit binding protein kinase binding protein phosphatase 2B binding protein phosphatase binding RNA binding | Mus musculus | Alternative splicing Endoplasmic reticulum Membrane Mitochondrion Mitochondrion outer membrane Phosphoprotein Reference proteome RNA-binding Transit peptide Transmembrane | MAIQLRSLFP | MAIQLRSLFPLALPGMLALLGWWWFFSRKKDRLSSSDKQVETLKVGPAIKDRRLSEEACPGVLSVAPTVTQPPGREEQRCVDKPSTEPLALPRTRQVRRRSESSGNLPSVADTRSQPGPCRDEIAKVELSLMGDKAKSIPLGCPLLPKDASFPYEAVERCKQESALGKTPGRGWPSPYAASGEKARETGGTEGTGDAVLGENVSEEGLLSQECVSEVEKSEFPILAPGGGEGEEVSHGPPQVAELLKKEEYIVGKLPSSFVEPVHSEPVKDEDALEPQVKGSSNTSDRDLAGELDKDETVPENDQIKQAAFQLISQVILE... | antiviral innate immune response apoptotic process negative regulation of cardiac muscle hypertrophy negative regulation of protein dephosphorylation negative regulation of protein import into nucleus endoplasmic reticulum; lipid droplet; membrane; mitochondrial crista; mitochondrial outer membrane; mitochondrion; neur... |
actin polymerization or depolymerization axon guidance cellular response to type II interferon central nervous system development negative regulation of epithelial cell migration negative regulation of ruffle assembly positive regulation of actin filament polymerization positive regulation of stress fiber assembly prot... | cytoplasm; focal adhesion; lamellipodium; phagocytic vesicle; stress fiber | actin binding profilin binding SH3 domain binding | Rattus norvegicus | Actin-binding Alternative splicing Cell projection Coiled coil Cytoplasm Cytoskeleton Phosphoprotein Reference proteome SH3-binding | MFAFEEFSEQ | MFAFEEFSEQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIYHNTASNTFRVVGVKLQDQQVVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMNSQEGGPSTQRQVQNGPSPEEMDIQRRQVMEQQHRQESLERRISATGPILPPGHPSSAASATFSCSGPPPPPPPPVPPPPTGSTPPPPPPLPAGGAQGTNHDESSASGLAAALAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKLLAKRRKAASQTDKPADRKEDENQTEDPSTSPSPGSRATSQPP... | actin polymerization or depolymerization axon guidance cellular response to type II interferon central nervous system development negative regulation of epithelial cell migration negative regulation of ruffle assembly positive regulation of actin filament polymerization positive regulation of stress fiber assembly prot... |
anterior/posterior axon guidance apoptotic process axon guidance netrin-activated signaling pathway neuron projection development | membrane raft; neuron projection membrane; neuronal cell body membrane; plasma membrane | netrin receptor activity | Rattus norvegicus | Apoptosis Cell membrane Cell projection Developmental protein Disulfide bond Glycoprotein Immunoglobulin domain Membrane Phosphoprotein Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix | MAVRPGLWPV | MAVRPGLWPVLLGIVLAAWLRGSGAQQSATVANPVPGANPDLLPHFLVEPEDVYIVKNKPVLLVCKAVPATQIFFKCNGEWVRQVDHVIERSTDSSSGLPTMEVRINVSRQQVEKVFGLEEYWCQCVAWSSSGTTKSQKAYIRIAYLRKNFEQEPLAKEVSLEQGIVLPCRPPEGIPPAEVEWLRNEDLVDPSLDPNVYITREHSLVVRQARLADTANYTCVAKNIVARRRSTSAAVIVYVNGGWSTWTEWSVCSASCGRGWQKRSRSCTNPAPLNGGAFCEGQNVQKTACATLCPVDGSWSSWSKWSACGLDCTHWRSR... | anterior/posterior axon guidance apoptotic process axon guidance netrin-activated signaling pathway neuron projection development membrane raft; neuron projection membrane; neuronal cell body membrane; plasma membrane netrin receptor activity Rattus norvegicus Apoptosis Cell membrane Cell projection Developmental prote... |
anterior/posterior axon guidance apoptotic process axon guidance negative regulation of extrinsic apoptotic signaling pathway in absence of ligand negative regulation of neuron apoptotic process positive regulation of extrinsic apoptotic signaling pathway in absence of ligand positive regulation of phosphatidylinositol... | membrane raft; plasma membrane | netrin receptor activity | Rattus norvegicus | 3D-structure Apoptosis Cell membrane Developmental protein Disulfide bond Glycoprotein Immunoglobulin domain Lipoprotein Membrane Palmitate Phosphoprotein Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix | MRARSGARGA | MRARSGARGALLLALLLCWDPTPSLAGIDSGGQALPDSFPSAPAEQLPHFLLEPEDAYIVKNKPVELHCRAFPATQIYFKCNGEWVSQKGHVTQESLDEATGLRIREVQIEVSRQQVEELFGLEDYWCQCVAWSSSGTTKSRRAYIRIAYLRKNFDQEPLAKEVPLDHEVLLQCRPPEGVPVAEVEWLKNEDVIDPAQDTNFLLTIDHNLIIRQARLSDTANYTCVAKNIVAKRRSTTATVIVYVNGGWSSWAEWSPCSNRCGRGWQKRTRTCTNPAPLNGGAFCEGQACQKTACTTVCPVDGAWTEWSKWSACSTECAH... | anterior/posterior axon guidance apoptotic process axon guidance negative regulation of extrinsic apoptotic signaling pathway in absence of ligand negative regulation of neuron apoptotic process positive regulation of extrinsic apoptotic signaling pathway in absence of ligand positive regulation of phosphatidylinositol... |
adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway galanin-activated signaling pathway inositol phosphate metabolic process neuron projection development neuropeptide signaling p... | cilium; plasma membrane | galanin receptor activity neuropeptide binding peptide hormone binding | Rattus norvegicus | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MNGSGSQGAE | MNGSGSQGAENTSQEGGSGGWQPEAVLVPLFFALIFLVGTVGNALVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDDWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLALLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDLCTFVFSYLLPVLVLSLTYARTLRYLWRTVDPVTAGSGSQRAKRKVTRMIIIVAVLFCLCWMPHHALILCVWFGRFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRKICAGLLRPAPRRASG... | adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway galanin-activated signaling pathway inositol phosphate metabolic process neuron projection development neuropeptide signaling p... |
apoptotic process extracellular matrix organization negative regulation of bone resorption negative regulation of odontogenesis of dentin-containing tooth negative regulation of osteoclast differentiation response to arsenic-containing substance response to estrogen response to inorganic substance response to magnesium... | extracellular matrix; extracellular space; receptor complex | cytokine activity | Rattus norvegicus | Apoptosis Cytokine Disulfide bond Glycoprotein Reference proteome Repeat Secreted Signal | MNKWLCCALL | MNKWLCCALLVFLDIIEWTTQETFPPKYLHYDPETGRQLLCDKCAPGTYLKQHCTVRRKTLCVPCPDYSYTDSWHTSDECVYCSPVCKELQTVKQECNRTHNRVCECEEGRYLELEFCLKHRSCPPGLGVLQAGTPERNTVCKRCPDGFFSGETSSKAPCRKHTNCSSLGLLLIQKGNATHDNVCSGNREATQNCGIDVTLCEEAFFRFAVPTKIIPNWLSVLVDSLPGTKVNAESVERIKRRHSSQEQTFQLLKLWKHQNRDQEMVKKIIQDIDLCESSVQRHIGHANLTTEQLRILMESLPGKKISPDEIERTRKTCK... | apoptotic process extracellular matrix organization negative regulation of bone resorption negative regulation of odontogenesis of dentin-containing tooth negative regulation of osteoclast differentiation response to arsenic-containing substance response to estrogen response to inorganic substance response to magnesium... |
glycogen biosynthetic process | cytoplasm | glucose binding glycogenin glucosyltransferase activity glycosyltransferase activity manganese ion binding protein homodimerization activity UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity | Rattus norvegicus | Acetylation Glycogen biosynthesis Glycoprotein Manganese Metal-binding Phosphoprotein Reference proteome Transferase | MTDQAFVTLT | MTDQAFVTLTTNDAYAKGALVLGSSLKQHRTTRRTVVLASPQVSDSMRKVLETVFDEVIMVDVLDSGDSAHLTLMKRPELGITLTKLHCWSLTQYSKCVFMDADTLVLSNIDDLFEREELSAAPDPGWPDCFNSGVFVYQPSIETYNQLLHLASEQGSFDGGDQGLLNTYFSGWATTDITKHLPFVYNLSSLSIYSYLPAFKAFGKNAKVVHFLGRTKPWNYTYNPQTKSVKCESQDPIVSHPEFLNLWWDTFTTNVLPLLQHHGLVKDAGSYLMMEHVTGALSDLSFGEAPPASQPSLSSEERKERWEQGQADYMGADS... | glycogen biosynthetic process cytoplasm glucose binding glycogenin glucosyltransferase activity glycosyltransferase activity manganese ion binding protein homodimerization activity UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity Rattus norvegicus Acetylation Glycogen biosynthesis Glycoprote... |
endoplasmic reticulum unfolded protein response fibroblast apoptotic process intrinsic apoptotic signaling pathway intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress positive regulation of apoptotic process positive regulation of striated muscle cell apoptotic process protein autoprocessi... | cytoplasm; endoplasmic reticulum | cysteine-type endopeptidase activity cysteine-type endopeptidase activity involved in execution phase of apoptosis cysteine-type peptidase activity endopeptidase activity protease binding | Mus musculus | Apoptosis Hydrolase Phosphoprotein Protease Reference proteome Thiol protease Zymogen | MAARRTHERD | MAARRTHERDPIYKIKGLAKDMLDGVFDDLVEKNVLNGDELLKIGESASFILNKAENLVENFLEKTDMAGKIFAGHIANSQEQLSLQFSNDEDDGPQKICTPSSPSESKRKVEDDEMEVNAGLAHESHLMLTAPHGLQSSEVQDTLKLCPRDQFCKIKTERAKEIYPVMEKEGRTRLALIICNKKFDYLFDRDNADTDILNMQELLENLGYSVVLKENLTAQEMETELMQFAGRPEHQSSDSTFLVFMSHGILEGICGVKHRNKKPDVLHDDTIFKIFNNSNCRSLRNKPKILIMQACRGRYNGTIWVSTNKGIATADTD... | endoplasmic reticulum unfolded protein response fibroblast apoptotic process intrinsic apoptotic signaling pathway intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress positive regulation of apoptotic process positive regulation of striated muscle cell apoptotic process protein autoprocessi... |
activation of innate immune response acute inflammatory response to non-antigenic stimulus axonal fasciculation cellular response to staurosporine epithelial cell differentiation hepatocyte apoptotic process intrinsic apoptotic signaling pathway by p53 class mediator positive regulation of apoptotic process positive re... | axon; cytoplasm; cytosol; neuronal cell body; nucleoplasm; nucleus | cysteine-type endopeptidase activity cysteine-type endopeptidase activity involved in apoptotic process cysteine-type endopeptidase activity involved in execution phase of apoptosis endopeptidase activity identical protein binding | Mus musculus | Apoptosis Autocatalytic cleavage Cytoplasm Hydrolase Lipoprotein Nucleus Palmitate Phosphoprotein Protease Reference proteome Thiol protease Zymogen | MTETDGFYKS | MTETDGFYKSREVFDPAEQYKMDHKRRGVALIFNHERFFWHLTLPERRGTNADRDNLTRRFSDLGFEVKCFNDLRAEELLLKIHEVSTSSHIDADCFICVFLSHGEGNHVYAYDAKIEIQTLTGLFKGDKCQSLVGKPKIFIIQACRGSQHDVPVVPLDMVDHQTDKLDNVTQVDAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLCEMLARYGSSLEFTELLTLVNRKVSQRRVDFCKDPDAIGKKQVPCFASMLTKKLHFCPKPSK | activation of innate immune response acute inflammatory response to non-antigenic stimulus axonal fasciculation cellular response to staurosporine epithelial cell differentiation hepatocyte apoptotic process intrinsic apoptotic signaling pathway by p53 class mediator positive regulation of apoptotic process positive re... |
ADP catabolic process ADP metabolic process AMP catabolic process AMP metabolic process ATP metabolic process energy homeostasis erythrocyte homeostasis GTP metabolic process IMP biosynthetic process IMP salvage | cytosol | AMP deaminase activity metal ion binding | Mus musculus | Hydrolase Metal-binding Nucleotide metabolism Phosphoprotein Reference proteome Zinc | MPRQFPKLNM | MPRQFPKLNMSDLDEHVRLLAEKVFAKVLREEDSKDVMSLFTVPEDCPIGQKEAKERELQKELAEQKSVETAKRKKSFKMIRSQSLSLQMPTQQDWKGPPTASPAMSPATPLVPGATSKPGPAPYAMPEYQRVTISGDYCAGITVEDYEQAAKSLAKALMIREKYARLAYHRFPRTTAQYLAHQGESVPLEEGLPDFHPPPLPQEDPYCLDDAPPNLGYLVRMHGGVLFVYDNQTMLERQEPHSLPYPDLETYIVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSNPHRDFYNVRKVDTHIHAA... | ADP catabolic process ADP metabolic process AMP catabolic process AMP metabolic process ATP metabolic process energy homeostasis erythrocyte homeostasis GTP metabolic process IMP biosynthetic process IMP salvage cytosol AMP deaminase activity metal ion binding Mus musculus Hydrolase Metal-binding Nucleotide metabolism ... |
axon guidance dendrite regeneration extracellular matrix organization glial cell migration neuron migration neuron projection development response to axon injury | basement membrane; collagen-containing extracellular matrix; extracellular matrix; extracellular space; matrilin complex | calcium ion binding | Mus musculus | Alternative splicing Coiled coil Disulfide bond EGF-like domain Glycoprotein Reference proteome Repeat Secreted Signal | MEKMLVGCLL | MEKMLVGCLLMLGQLFLVLPVDGRERPQARFPSRGRHVRMYPQTALLESSCENKRADLVFIIDSSRSVNTYDYAKVKEFILDILQFLDIGPDVTRVGLLQYGSTVKNEFSLKTFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVPRIIMIVTDGRPQDSVAEVAAKARNTGILIFAIGVGQVDLNTLKAIGSEPHKDHVFLVANFSQIESLTSVFQNKLCTVHMCSVLEHNCAHFCLNTPGSYICKCKQGYILSTDQKTCRIQDLCATEDHGCEQLCVNMLGSFVCQCYSGYTLAEDGKRCTA... | axon guidance dendrite regeneration extracellular matrix organization glial cell migration neuron migration neuron projection development response to axon injury basement membrane; collagen-containing extracellular matrix; extracellular matrix; extracellular space; matrilin complex calcium ion binding Mus musculus Alte... |
anterior/posterior axon guidance apoptotic process axon guidance brain development chemorepulsion of axon dorsal root ganglion development ectopic germ cell programmed cell death netrin-activated signaling pathway positive regulation of apoptotic process positive regulation of developmental process positive regulation ... | axon; cell surface; dendrite; filopodium; growth cone; lamellipodium; neuronal cell body; plasma membrane; synapse | netrin receptor activity netrin receptor activity involved in chemorepulsion protein kinase binding tubulin binding | Mus musculus | Alternative splicing Apoptosis Cell membrane Cell projection Developmental protein Disulfide bond Glycoprotein Immunoglobulin domain Membrane Phosphoprotein Receptor Reference proteome Repeat Signal Synapse Synaptosome Transmembrane Transmembrane helix | MRKGLRATAA | MRKGLRATAARCGLGLGYLLQMLVLPALALLSASGTGSAAQDDEFFHELPETFPSDPPEPLPHFLIEPEEAYIVKNKPVNLYCKASPATQIYFKCNSEWVHQKDHVVDERVDETSGLIVREVSIEISRQQVEELFGPEDYWCQCVAWSSAGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKNEDIIDPAEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIVYVNGGWSTWTEWSVCNSRCGRGYQKRTRTCTNPAPLNGGAFCEGQSVQKIACTTLCPVDGRWT... | anterior/posterior axon guidance apoptotic process axon guidance brain development chemorepulsion of axon dorsal root ganglion development ectopic germ cell programmed cell death netrin-activated signaling pathway positive regulation of apoptotic process positive regulation of developmental process positive regulation ... |
cellular response to interleukin-4 circadian rhythm immune response natural killer cell differentiation negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II positive regulation of DNA-templated transcription positive regulation of gene expression regulation of DNA... | nucleus; RNA polymerase II transcription regulator complex | DNA-binding transcription factor activity DNA-binding transcription repressor activity, RNA polymerase II-specific identical protein binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding | Mus musculus | Activator Biological rhythms DNA-binding Isopeptide bond Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation Ubl conjugation | MQLRKMQTIK | MQLRKMQTIKKEPAPLDPTSSSDKMLLLNSALAEVAEDLASGEDLLLNEGSMGKNKSSACRRKREFIPDEKKDAMYWEKRRKNNEAAKRSREKRRLNDLVLENKLIALGEENATLKAELLSLKLKFGLISSTAYAQEIQKLSNSTAVYFQDYQTSKAAVSSFVDEHEPAMVAGSCISVIKHSPQSSLSDVSEVSSVEHTQESPAQGGCRSPENKFPVIKQEPVELESFAREAREERGTYSTSIYQSYMGSSFSTYSHSPPLLQVHGSTSNSPRTSEADEGVVGKSSDGEDEQQVPKGPIHSPVELQRVHATVVKVPEVNP... | cellular response to interleukin-4 circadian rhythm immune response natural killer cell differentiation negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II positive regulation of DNA-templated transcription positive regulation of gene expression regulation of DNA... |
anatomical structure morphogenesis B cell differentiation cell fate commitment cell migration cilium assembly endocrine pancreas development endoderm development enteroendocrine cell differentiation epithelial cell development glucose metabolic process liver development negative regulation of transforming growth factor... | nucleoplasm; nucleus | chromatin binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded D... | Mus musculus | 3D-structure Activator DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation | MNAQLTMEAI | MNAQLTMEAIGELHGVSHEPVPAPADLLGGSPHARSSVGHRGSHLPPAHPRSMGMASLLDGGSGGSDYHHHHRAPEHSLAGPLHPTMTMACETPPGMSMPTTYTTLTPLQPLPPISTVSDKFPHHHHHHHHHHHPHHHQRLAGNVSGSFTLMRDERGLASMNNLYTPYHKDVAGMGQSLSPLSGSGLGSIHNSQQGLPHYAHPGAAMPTDKMLTPNGFEAHHPAMLGRHGEQHLTPTSAGMVPINGLPPHHPHAHLNAQGHGQLLGTAREPNPSVTGAQVSNGSNSGQMEEINTKEVAQRITTELKRYSIPQAIFAQRVL... | anatomical structure morphogenesis B cell differentiation cell fate commitment cell migration cilium assembly endocrine pancreas development endoderm development enteroendocrine cell differentiation epithelial cell development glucose metabolic process liver development negative regulation of transforming growth factor... |
androgen metabolic process bile acid biosynthetic process brexanolone metabolic process C21-steroid hormone metabolic process estrogen metabolic process fatty acid beta-oxidation fatty acid metabolic process isoleucine catabolic process mitochondrial tRNA 3'-end processing mitochondrial tRNA 5'-end processing mitochond... | endoplasmic reticulum; mitochondrial inner membrane; mitochondrial nucleoid; mitochondrial ribonuclease P complex; mitochondrion; tRNA methyltransferase complex | 17-beta-hydroxysteroid dehydrogenase (NAD+) activity 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity 3-hydroxyacyl-CoA dehydrogenase activity acetoacetyl-CoA reductase activity amyloid-beta binding androstan-3-alpha,17-beta-diol dehydrogenase activity chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity cholate... | Mus musculus | Acetylation Direct protein sequencing Fatty acid metabolism Lipid metabolism Mitochondrion Mitochondrion nucleoid NAD Oxidoreductase Reference proteome Steroid metabolism tRNA processing | MAAAVRSVKG | MAAAVRSVKGLVAVVTGGASGPWLATAKRLVGQGATAVLLDVPDSEGESQAKKLGESCIFAPANVTSEKEIQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHQKKNKIHTLEDFQRVINVNLIGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIDGMTLPIARDLAPTGIRVVTIAPGLFATPLLTTLPEKVRNFLASQVPFPSRLGDPAEYAHLVQTIIENPFLNGEVIRLDGAIRMQP | androgen metabolic process bile acid biosynthetic process brexanolone metabolic process C21-steroid hormone metabolic process estrogen metabolic process fatty acid beta-oxidation fatty acid metabolic process isoleucine catabolic process mitochondrial tRNA 3'-end processing mitochondrial tRNA 5'-end processing mitochond... |
base-excision repair base-excision repair, AP site formation cellular response to cadmium ion DNA damage response DNA repair negative regulation of apoptotic process negative regulation of double-strand break repair via single-strand annealing nucleotide-excision repair regulation of DNA-templated transcription respons... | mitochondrion; nuclear matrix; nuclear speck; nucleoplasm; nucleus; protein-containing complex | 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity class I DNA-(apurinic or apyrimidinic site) endonuclease activity damaged DNA binding DNA binding DNA N-glycosylase activity microtubule binding oxidized base lesion DNA N-glycosylase activity oxidized purine DNA binding oxidized purine nucleobase lesion DNA N-glycosy... | Mus musculus | 3D-structure DNA damage DNA repair Glycosidase Hydrolase Lyase Multifunctional enzyme Nucleus Reference proteome | MLFRSWLPSS | MLFRSWLPSSMRHRTLSSSPALWASIPCPRSELRLDLVLASGQSFRWKEQSPAHWSGVLADQVWTLTQTEDQLYCTVYRGDDSQVSRPTLEELETLHKYFQLDVSLAQLYSHWASVDSHFQRVAQKFQGVRLLRQDPTECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPNLHALAGPEAETHLRKLGLGYRARYVRASAKAILEEQGGPAWLQQLRVAPYEEAHKALCTLPGVGAKVADCICLMALDKPQAVPVDVHVWQIAHRDYGWHPKTSQAKGPSPLANKELGNFFRNLWGPYAGWAQAVLFS... | base-excision repair base-excision repair, AP site formation cellular response to cadmium ion DNA damage response DNA repair negative regulation of apoptotic process negative regulation of double-strand break repair via single-strand annealing nucleotide-excision repair regulation of DNA-templated transcription respons... |
exocytosis proteolysis zymogen activation | axon; cytoplasmic vesicle; dendrite; plasma membrane; synapse; synaptic cleft; terminal bouton | peptidase activity serine-type endopeptidase activity | Mus musculus | 3D-structure Disulfide bond Glycoprotein Hydrolase Kringle Protease Reference proteome Repeat Secreted Serine protease Signal | MALARCVLAV | MALARCVLAVILGALSVVARADPVSRSPLHRPHPSPPRSQHAHYLPSSRRPPRTPRFPLPLRIPAAQRPQVLSTGHTPPTIPRRCGAGESWGNATNLGVPCLHWDEVPPFLERSPPASWAELRGQPHNFCRSPDGSGRPWCFYRNAQGKVDWGYCDCGQGPALPVIRLVGGNSGHEGRVELYHAGQWGTICDDQWDNADADVICRQLGLSGIAKAWHQAHFGEGSGPILLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCVPLTDGVIRLAGGKSTHEGRLEVYYKGQWGTVCDDGWTEMNTYVACRLLGFKYGK... | exocytosis proteolysis zymogen activation axon; cytoplasmic vesicle; dendrite; plasma membrane; synapse; synaptic cleft; terminal bouton peptidase activity serine-type endopeptidase activity Mus musculus 3D-structure Disulfide bond Glycoprotein Hydrolase Kringle Protease Reference proteome Repeat Secreted Serine protea... |
cell division chromosome segregation learning long-term memory long-term synaptic potentiation mitotic cell cycle modulation of chemical synaptic transmission negative regulation of ERK1 and ERK2 cascade negative regulation of G protein-coupled receptor signaling pathway negative regulation of MAP kinase activity negat... | centrosome; cytoplasm; dendrite; dendritic spine; glutamatergic synapse; microtubule; nuclear body; nucleus; plasma membrane; PML body; postsynaptic density; spindle; spindle pole | G-protein alpha-subunit binding GDP-dissociation inhibitor activity GTPase activating protein binding GTPase activator activity microtubule binding protein kinase binding signaling receptor complex adaptor activity | Rattus norvegicus | 3D-structure Cell cycle Cell division Cell membrane Cell projection Cytoplasm Cytoskeleton Developmental protein GTPase activation Membrane Microtubule Nucleus Phosphoprotein Reference proteome Repeat Signal transduction inhibitor Synapse | MPGKPKHLGV | MPGKPKHLGVPNGRMVLAVSDGELTSTSGSQAQGEGRGSSLSIHSLPSGPSSPFSTDEQPVASWAQSFERLLQDPRGLAYFTEFLKKEFSAENVTFWQACERFQQIPASDTKQLAQEAHNIYHEFLSSQALSPVNIDRQAWLSEEVLAQPRPDMFRAQQLQIFNLMKFDSYARFVKSPLYQECLLAEAEGRPLREPGSSHLGSPDTARKKPKLKPGKSLPLGVEELGQLPLAEGRPLRKSFRREMPGGAVNSALRRESQGSLNSSASLDLGFLAFVSSKSESHRKSLGSGEGESESRPGKYCCVYLPDGTASLALARPGL... | cell division chromosome segregation learning long-term memory long-term synaptic potentiation mitotic cell cycle modulation of chemical synaptic transmission negative regulation of ERK1 and ERK2 cascade negative regulation of G protein-coupled receptor signaling pathway negative regulation of MAP kinase activity negat... |
cellular response to ionizing radiation circadian regulation of gene expression circadian rhythm DNA damage checkpoint signaling negative regulation of DNA-templated transcription negative regulation of glucocorticoid receptor signaling pathway positive regulation of circadian rhythm positive regulation of DNA-template... | chromatoid body; chromosome; CLOCK-BMAL transcription complex; cytoplasm; cytosol; intracellular membrane-bounded organelle; nucleoplasm; nucleus; perichromatin fibrils; transcription regulator complex | chromatin DNA binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific E-box binding histone acetyltransferase activity protein dimerization activity RNA polymerase II cis-... | Mus musculus | 3D-structure Activator Acyltransferase Alternative splicing Biological rhythms Cytoplasm DNA damage DNA-binding Glycoprotein Isopeptide bond Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation Transferase Ubl conjugation | MVFTVSCSKM | MVFTVSCSKMSSIVDRDDSSIFDGLVEEDDKDKAKRVSRNKSEKKRRDQFNVLIKELGSMLPGNARKMDKSTVLQKSIDFLRKHKETTAQSDASEIRQDWKPTFLSNEEFTQLMLEALDGFFLAIMTDGSIIYVSESVTSLLEHLPSDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEYLKSKNQLEFCCHMLRGTIDPKEPSTYEYVRFIGNFKSLTSVSTSTHNGFEGTIQRTHRPSYEDRVCFVATVRLATPQFIKEMCTVEEPNEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHVDDLEN... | cellular response to ionizing radiation circadian regulation of gene expression circadian rhythm DNA damage checkpoint signaling negative regulation of DNA-templated transcription negative regulation of glucocorticoid receptor signaling pathway positive regulation of circadian rhythm positive regulation of DNA-template... |
axonogenesis cellular response to hormone stimulus cholecystokinin signaling pathway eating behavior feeding behavior forebrain development G protein-coupled receptor signaling pathway gastric acid secretion insulin secretion neuron migration positive regulation of cytosolic calcium ion concentration positive regulatio... | cytosol; endosome; membrane; nucleoplasm; plasma membrane; terminal bouton | cholecystokinin receptor activity peptide binding peptide hormone binding | Mus musculus | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MDVVDSLLMN | MDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSAVQILLYSFIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLIPGVVMVVAYGLISLELYQGIKFDASQKKSAKEKRLSSGGGGGGGSSSSRYEDSDGCYLQKSRPPRKLELQQLSTSSSGGRINRIRSSGSAANLIAKKRVI... | axonogenesis cellular response to hormone stimulus cholecystokinin signaling pathway eating behavior feeding behavior forebrain development G protein-coupled receptor signaling pathway gastric acid secretion insulin secretion neuron migration positive regulation of cytosolic calcium ion concentration positive regulatio... |
cellular senescence negative regulation of apoptotic signaling pathway negative regulation of transcription by RNA polymerase II regulation of cell cycle regulation of DNA-templated transcription regulation of transcription by RNA polymerase II | nucleoplasm; nucleus | chromatin binding DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific identical protein binding protein dimerization activity RNA polymerase II cis-regulatory region sequence-... | Mus musculus | Acetylation DNA-binding Nucleus Reference proteome Repressor Transcription Transcription regulation | MSIETLLEAA | MSIETLLEAARFLEWQAQQQQRAREEQERLRLEREREREQEQKRASNLARLAHALPVEEPRIEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQSLPPPPPLPPAAQPLPLAPRQPALVSTPGLSIKEPVTLPTRPQVPTPAPLLPDAKTTVAPTGSPKPLQPLPAPILTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEAKSSEQKKRPGGIGTREVHNKLEKNRRAHLKECFETLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREKIATQQRLAELKHELSQWMDVLEIDRVLRQ... | cellular senescence negative regulation of apoptotic signaling pathway negative regulation of transcription by RNA polymerase II regulation of cell cycle regulation of DNA-templated transcription regulation of transcription by RNA polymerase II nucleoplasm; nucleus chromatin binding DNA binding DNA-binding transcriptio... |
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway calcium-mediated signaling cell surface receptor signaling pathway cellular response to amyloid-beta chemotaxis complement receptor mediated signaling pathway defense response to bacterium G protein-coupled receptor signaling pathway immune respo... | cytoplasm; plasma membrane | amyloid-beta binding complement receptor activity N-formyl peptide receptor activity RAGE receptor binding scavenger receptor binding signaling receptor activity | Mus musculus | Cell membrane Chemotaxis Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Transducer Transmembrane Transmembrane helix | METNYSIPLN | METNYSIPLNGSDVVIYDSTISRVLWILSMVVVSITFFLGVLGNGLVIWVAGFRMPHTVTTIWYLNLALADFSFTATLPFLLVEMAMKEKWPFGWFLCKLVHIAVDVNLFGSVFLIAVIALDRCICVLHPVWAQNHRTVSLARNVVVGSWIFALILTLPLFLFLTTVRDARGDVHCRLSFVSWGNSVEERLNTAITFVTTRGIIRFIVSFSLPMSFVAICYGLITTKIHKKAFVNSSRPFRVLTGVVASFFICWFPFQLVALLGTVWLKEMQFSGSYKIIGRLVNPTSSLAFFNSCLNPILYVFMGQDFQERLIHSLSSR... | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway calcium-mediated signaling cell surface receptor signaling pathway cellular response to amyloid-beta chemotaxis complement receptor mediated signaling pathway defense response to bacterium G protein-coupled receptor signaling pathway immune respo... |
positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II | nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding | Mus musculus | Activator Alternative splicing Developmental protein DNA-binding Metal-binding Nucleus Reference proteome Transcription Transcription regulation Zinc Zinc-finger | MFGIQENIPR | MFGIQENIPRGGTTMKEEPLGSGMNPVRSWMHTAGVVDANTAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVDFVEKEKEPNNEKTNNGIHYKLQLLYSNGVRTEQDLYVRLIDSMTKQAIVYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSEGTAPSYLENATPCIKAISPSEGWTTGGATVIIIGDNFFDGLQVVFGTMLVWSELITPHAIRVQTPPRHI... | positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II nucleus DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific metal ion b... |
adipose tissue development brown fat cell differentiation cell fate determination positive regulation of cold-induced thermogenesis positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II | nucleus | chromatin binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding | Mus musculus | Activator Developmental protein DNA-binding Metal-binding Nucleus Reference proteome Transcription Transcription regulation Zinc Zinc-finger | MFGIQDTLGR | MFGIQDTLGRGPALKDKSLGAEMDSVRSWVRNVGVVDANVAAQSGVALSRAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVDFVENDKEQGNEKTNNGTHYKLQLLYSNGVRTEQDLYVRLIDSVTKQPIAYEGQNKNPEMCRVLLTHEVMCSRCCEKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKTAGNPRDMRRFQVVLSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSEATPCIKAISPSEGWTTGGAMVIIIGDNFFDGLQVVFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSY... | adipose tissue development brown fat cell differentiation cell fate determination positive regulation of cold-induced thermogenesis positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II nucleus chromatin binding DNA ... |
in utero embryonic development liver development N-glycan processing negative regulation of neuron projection development nitrogen compound metabolic process | endoplasmic reticulum; glucosidase II complex; intracellular membrane-bounded organelle | calcium ion binding phosphoprotein binding protein kinase C binding protein-containing complex binding RNA binding transmembrane transporter binding | Mus musculus | 3D-structure Alternative splicing Calcium Direct protein sequencing Disulfide bond Endoplasmic reticulum Glycoprotein Metal-binding Phosphoprotein Reference proteome Repeat Signal | MLLLLLLLLP | MLLLLLLLLPLCWAVEVKRPRGVSLSNHHFYEESKPFTCLDGTATIPFDQVNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYILSSRVNDGVCDCCDGTDEYNSGTVCENTCREKGRKEKESLQQLAEVTREGFRLKKILIEEWKTAREEKQSKLLELQAGKKSLEDQVETLRAAKEEAERPEKEAKDQHRKLWEEQQAAAKARREQERAASAFQELDDNMDGMVSLAELQTHPELDTDGDGALSEEEAQALLSGDTQTDTTSFYDRVWAAIRDKYRSEVPPTDIPVPEETEPKEEKPPVLPPTEEEEEEEEEPEE... | in utero embryonic development liver development N-glycan processing negative regulation of neuron projection development nitrogen compound metabolic process endoplasmic reticulum; glucosidase II complex; intracellular membrane-bounded organelle calcium ion binding phosphoprotein binding protein kinase C binding protei... |
cellular response to anoxia cellular response to brain-derived neurotrophic factor stimulus cellular response to calcium ion cellular response to cAMP cellular response to insulin stimulus myosin II filament disassembly negative regulation of apoptotic process phosphorylation positive regulation of dendritic spine morp... | dendritic spine; glutamatergic synapse; postsynaptic density | ATP binding calcium ion binding calmodulin binding elongation factor-2 kinase activity translation factor activity, RNA binding | Mus musculus | Acetylation ATP-binding Calcium Calmodulin-binding Kinase Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MADEDLIFCL | MADEDLIFCLEGVDGGRCSRAGHNADSDTDSDDDEGYFICPITDDHMSNQNVSSKVQSYYSNLTKTECGSTGSPASSFHFKEAWKHAIEKAKHMPDPWAEFHLEDIATEHATRHRYNAVTGEWLKDEVLIKMASQPFGRGAMRECFRTKKLSNFLHAQQWKGASNYVAKRYIEPVDRSVYFEDVQLQMEAKLWGEDYNRHKPPKQVDIMQMCIIELKDRPGQPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFYSHACNRICQSM... | cellular response to anoxia cellular response to brain-derived neurotrophic factor stimulus cellular response to calcium ion cellular response to cAMP cellular response to insulin stimulus myosin II filament disassembly negative regulation of apoptotic process phosphorylation positive regulation of dendritic spine morp... |
cell redox homeostasis extracellular matrix organization hydrogen peroxide catabolic process male gonad development negative regulation of male germ cell proliferation protein maturation by protein folding reactive oxygen species metabolic process response to oxidative stress spermatogenesis | cytoplasm; cytosol; endoplasmic reticulum; extracellular space; mitochondrion; smooth endoplasmic reticulum | identical protein binding molecular adaptor activity molecular sequestering activity thioredoxin peroxidase activity | Mus musculus | 3D-structure Antioxidant Cytoplasm Direct protein sequencing Disulfide bond Endoplasmic reticulum Oxidoreductase Peroxidase Redox-active center Reference proteome Signal | MEARSKLLDG | MEARSKLLDGTTASRRWTRKLVLLLPPLLLFLLRTESLQGLESDERFRTRENECHFYAGGQVYPGEASRVSVADHSLHLSKAKISKPAPYWEGTAVINGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRIEEFKSINTEVVACSVDSQFTHLAWINTPRRQGGLGPIRIPLLSDLNHQISKDYGVYLEDSGHTLRGLFIIDDKGVLRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDKLN | cell redox homeostasis extracellular matrix organization hydrogen peroxide catabolic process male gonad development negative regulation of male germ cell proliferation protein maturation by protein folding reactive oxygen species metabolic process response to oxidative stress spermatogenesis cytoplasm; cytosol; endopla... |
mRNA splicing, via spliceosome | Cajal body; catalytic step 2 spliceosome; cytosol; intracellular membrane-bounded organelle; nuclear speck; nucleoplasm; nucleus; U2-type catalytic step 2 spliceosome; U2-type precatalytic spliceosome; U4/U6 x U5 tri-snRNP complex | GTP binding GTPase activity U5 snRNA binding | Mus musculus | Acetylation GTP-binding Isopeptide bond mRNA processing mRNA splicing Nucleotide-binding Nucleus Phosphoprotein Reference proteome Spliceosome Ubl conjugation | MDTDLYDEFG | MDTDLYDEFGNYIGPELDSDEDDDELGRETKDLDEDEDEDEDDVGEHEDDHPGMEVVLHEDKKYYPTAEEVYGPEVETIVQEEDTQPLTEPIIKPVKTKKFTLMEQTLPVTVYEMDFLADLMDNSELIRNVTLCGHLHHGKTCFVDCLIEQTHPEIRKRYDQDLCYTDILFTEQERGVGIKSTPVTVVLPDTKGKSYLFNIMDTPGHVNFSDEVTAGLRISDGVVLFIDAAEGVMLNTERLIKHAVQERLAVTVCINKIDRLILELKLPPTDAYYKLRHIVDEVNGLISMYSTDENLILSPLLGNVCFSSSQYSICFTLG... | mRNA splicing, via spliceosome Cajal body; catalytic step 2 spliceosome; cytosol; intracellular membrane-bounded organelle; nuclear speck; nucleoplasm; nucleus; U2-type catalytic step 2 spliceosome; U2-type precatalytic spliceosome; U4/U6 x U5 tri-snRNP complex GTP binding GTPase activity U5 snRNA binding Mus musculus ... |
L-arginine import across plasma membrane L-arginine transmembrane transport L-lysine import across plasma membrane L-lysine transmembrane transport L-ornithine import across plasma membrane L-ornithine transmembrane transport lysine transport ornithine transport regulation of TOR signaling | plasma membrane | basic amino acid transmembrane transporter activity L-arginine transmembrane transporter activity L-lysine transmembrane transporter activity L-ornithine transmembrane transporter activity | Rattus norvegicus | Amino-acid transport Cell membrane Glycoprotein Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport | MLWQALRRFG | MLWQALRRFGQKLVRRRLLELGMGETRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKEKAGPSIVICFLVAALSSVLAGLCYAEFGARVPGSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNHISQTLKGTILLNMPHVLAEYPDFFALALVLLLTGLLVLGANESGLVTKVFTGMNLLVLGFVIISGFIKGELRNWKLTKEDYCLTMSESNGTCSLDSMGSGGFMPFGLEGILRGAATCFYAFVGFDCIATTGEEAQNPQRSIPMGIVISLSICFLAYFGVSSALTLMMPYYKLQPESP... | L-arginine import across plasma membrane L-arginine transmembrane transport L-lysine import across plasma membrane L-lysine transmembrane transport L-ornithine import across plasma membrane L-ornithine transmembrane transport lysine transport ornithine transport regulation of TOR signaling plasma membrane basic amino a... |
actin cytoskeleton organization actin filament polymerization cell division dendritic spine morphogenesis membrane invagination negative regulation of lymphocyte migration negative regulation of membrane tubulation plasma membrane tubulation positive regulation of chemotaxis positive regulation of clathrin-dependent en... | actin cap; cell leading edge; cytoplasmic vesicle; cytosol; glutamatergic synapse; Golgi membrane; lamellipodium; nucleus; postsynapse | actin binding cytoskeletal protein binding identical protein binding | Rattus norvegicus | 3D-structure Acetylation Actin-binding Cell cycle Cell division Cytoplasm Cytoskeleton Methylation Mitosis Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation | MSSGQQPPRR | MSSGQQPPRRVTNVGSLLLTPQENESLFSFLGKKCVTMSSAVVQLYAADRNCMWSKKCSGVACLVKDNPQRSYFLRIFDIKDGKLLWEQELYNNFVYNSPRGYFHTFAGDTCQVALNFANEEEAKKFRKAVTDLLGRRQRKSEKRRDAPNGPNLPMATVDIKNPEITTNRFYSSQVNNISHTKEKKKGKAKKKRLTKADIGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCGISEAQLKDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHSSGPPPPPARGRGAPPPPPSRAPTAAPP... | actin cytoskeleton organization actin filament polymerization cell division dendritic spine morphogenesis membrane invagination negative regulation of lymphocyte migration negative regulation of membrane tubulation plasma membrane tubulation positive regulation of chemotaxis positive regulation of clathrin-dependent en... |
protein O-linked glycosylation protein O-linked glycosylation via serine protein O-linked glycosylation via threonine | Golgi apparatus; Golgi membrane; perinuclear region of cytoplasm | carbohydrate binding manganese ion binding polypeptide N-acetylgalactosaminyltransferase activity | Mus musculus | Disulfide bond Glycoprotein Glycosyltransferase Golgi apparatus Lectin Manganese Membrane Metal-binding Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix | MAVRWTWAGK | MAVRWTWAGKSCLLLALLTLAYILVEFSVSTLYASPGAGGARELGPRRLPDLDTREEDLSQPLYIKPPADSHALGEWGRASKLQLNEGELKQQEELIERYAINIYLSDRISLHRHIEDKRMYECKAKKFHYRSLPTTSVIIAFYNEAWSTLLRTIHSVLETSPAVLLKEIILVDDLSDRIYLKAQLETYISNLERVRLIRTNKREGLVRARLIGATFATGDVLTFLDCHCECNTGWLEPLLERISRDETAIVCPVIDTIDWNTFEFYMQTGEPMIGGFDWRLTFQWHSVPKHERDRRTSRIDPIRSPTMAGGLFAVSKKY... | protein O-linked glycosylation protein O-linked glycosylation via serine protein O-linked glycosylation via threonine Golgi apparatus; Golgi membrane; perinuclear region of cytoplasm carbohydrate binding manganese ion binding polypeptide N-acetylgalactosaminyltransferase activity Mus musculus Disulfide bond Glycoprotei... |
autophagy calcium ion regulated lysosome exocytosis calcium ion-regulated exocytosis of neurotransmitter cellular response to calcium ion establishment of vesicle localization learning memory negative regulation of clathrin coat assembly negative regulation of clathrin-dependent endocytosis negative regulation of cytok... | axon; cell body; clathrin-coated vesicle membrane; cytoplasm; dendrite; dendritic spine; dopaminergic synapse; early phagosome; excitatory synapse; exocytic vesicle; inhibitory synapse; lysosomal membrane; lysosome; neuron projection; perikaryon; perinuclear region of cytoplasm; phagocytic cup; phagocytic vesicle; plas... | beta-tubulin binding clathrin binding identical protein binding metal ion binding phosphatidylserine binding SNARE binding translation initiation factor binding ubiquitin protein ligase binding | Rattus norvegicus | Calcium Cell projection Cytoplasmic vesicle Endosome Golgi apparatus Lysosome Membrane Metal-binding Phosphoprotein Reference proteome Repeat Synapse Transmembrane Transmembrane helix Ubl conjugation | MAEITNIRPS | MAEITNIRPSFDVSPVAAGLIGASVLVVCVSVTVFVWTCCHQQAEKKHKTPPYKFIHMLKGISIYPETLSNKKKIIKVRRDKDGSHRESGRGNLLVNAESGLLSHDRDPRGPSPASCIDQLPIKRDYGEELRSPMTSLTPGESKPTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDGQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPKM... | autophagy calcium ion regulated lysosome exocytosis calcium ion-regulated exocytosis of neurotransmitter cellular response to calcium ion establishment of vesicle localization learning memory negative regulation of clathrin coat assembly negative regulation of clathrin-dependent endocytosis negative regulation of cytok... |
B cell activation negative regulation of apoptotic signaling pathway negative regulation of protein dephosphorylation negative regulation of stress-activated MAPK cascade negative regulation of transcription by RNA polymerase II positive regulation of dephosphorylation positive regulation of transcription by RNA polyme... | cytoplasm; cytosol; microtubule | enzyme binding mitogen-activated protein kinase kinase binding protein domain specific binding protein phosphatase 2A binding protein phosphatase regulator activity protein-containing complex binding | Rattus norvegicus | Acetylation B-cell activation Chaperone Cytoplasm Phosphoprotein Reference proteome Ubl conjugation | MAASEEELLL | MAASEEELLLPRLPELFETSKKLLEELEVATEPTGSRTIQDKVSKGLELLEKAAGMLSQLDLFSRNEDLEEIASIDLKYLMVPALQGALTMKQVNPSKRLDHLQRAREHFIHFLTQCHCYHVAEFQLPQTKNNSAENNTARSSMAYPNLVAMASQRQAKIERYKQKKEVEHRLSALKSAVESGQADDERVREYYLLHLRRWIGISLEEIESIDQEIKILKDKDSPREESACQSSLPEKPPMKPFILTRNKAQAKVFGTGYPSLATMTVSDWYEQHQKYGALPDRGIAKPPSADFQRAAQQQEDQEQKDEENEEKALHRMR... | B cell activation negative regulation of apoptotic signaling pathway negative regulation of protein dephosphorylation negative regulation of stress-activated MAPK cascade negative regulation of transcription by RNA polymerase II positive regulation of dephosphorylation positive regulation of transcription by RNA polyme... |
cellular response to fibroblast growth factor stimulus cellular response to interleukin-2 cellular response to nerve growth factor stimulus cellular response to prolactin cellular response to wortmannin DNA damage checkpoint signaling DNA repair G2/M transition of mitotic cell cycle mRNA splicing, via spliceosome posit... | catalytic step 2 spliceosome; cytoplasm; DNA replication factor A complex; nuclear speck; nucleus; perinuclear region of cytoplasm; protein-DNA complex; Prp19 complex; spliceosomal complex; U2-type catalytic step 2 spliceosome | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific identical protein binding leucine zipper domain binding protein kinase binding protein phosphatase 1 binding RNA binding RNA polymerase II transcription regulatory region sequen... | Rattus norvegicus | Activator Cell cycle Coiled coil Cytoplasm Direct protein sequencing DNA damage DNA repair DNA-binding Isopeptide bond mRNA processing mRNA splicing Nucleus Phosphoprotein Reference proteome Repeat RNA-binding Spliceosome Transcription Transcription regulation Ubl conjugation | MPRIMIKGGV | MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKKKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKKDKQHLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEVA... | cellular response to fibroblast growth factor stimulus cellular response to interleukin-2 cellular response to nerve growth factor stimulus cellular response to prolactin cellular response to wortmannin DNA damage checkpoint signaling DNA repair G2/M transition of mitotic cell cycle mRNA splicing, via spliceosome posit... |
learning positive regulation of endocytosis synaptic vesicle endocytosis | axon terminus; cytoskeleton; extrinsic component of synaptic vesicle membrane; glutamatergic synapse; leading edge membrane; photoreceptor ribbon synapse; plasma membrane; presynapse; presynaptic endocytic zone; synapse; synaptic vesicle; terminal bouton | phosphatase binding phospholipid binding protein-containing complex binding | Rattus norvegicus | 3D-structure Coiled coil Cytoplasm Cytoplasmic vesicle Cytoskeleton Direct protein sequencing Membrane Phosphoprotein Reference proteome SH3 domain Synapse | MADIKTGIFA | MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAFSIQGAPSDSGPLRIAKTPSPPEEASPLPSPTASPNHTLAPASPAPVRPRSPSQTRKGPPVPPLPKVTPTKELQQENI... | learning positive regulation of endocytosis synaptic vesicle endocytosis axon terminus; cytoskeleton; extrinsic component of synaptic vesicle membrane; glutamatergic synapse; leading edge membrane; photoreceptor ribbon synapse; plasma membrane; presynapse; presynaptic endocytic zone; synapse; synaptic vesicle; terminal... |
endosome to lysosome transport lipid tube assembly muscle cell differentiation negative regulation of amyloid-beta formation negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel negative regulation of potassium ion transmembrane transport negative regulation of transcription... | axon; axon initial segment; axon terminus; cerebellar mossy fiber; cytosol; dendrite; endosome; extrinsic component of synaptic vesicle membrane; glutamatergic synapse; I band; lipid tube; membrane; microtubule; node of Ranvier; nuclear envelope; nucleus; plasma membrane; RNA polymerase II transcription repressor compl... | actin filament binding aspartic-type endopeptidase inhibitor activity GTPase binding identical protein binding phospholipid binding protease binding protein-containing complex binding protein-folding chaperone binding RNA polymerase binding tau protein binding | Rattus norvegicus | 3D-structure Acetylation Alternative splicing Cell membrane Coiled coil Cytoplasm Developmental protein Differentiation Direct protein sequencing Endocytosis Endosome Membrane Nucleus Phosphoprotein Reference proteome SH3 domain | MAEMGSKGVT | MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTYLASVKAMHEASKKLSECLQEVYEPEWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEKAAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVSLEKQHGSNTFTVKAQPSDSAPEKGNKSPSPPPDGSPAATPEIRVNHEPEPA... | endosome to lysosome transport lipid tube assembly muscle cell differentiation negative regulation of amyloid-beta formation negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel negative regulation of potassium ion transmembrane transport negative regulation of transcription... |
extracellular matrix assembly negative regulation of macroautophagy | extracellular exosome; extracellular space; Golgi membrane; intercellular bridge | FAD binding flavin-dependent sulfhydryl oxidase activity protein disulfide isomerase activity | Cavia porcellus | Disulfide bond FAD Flavoprotein Glycoprotein Oxidoreductase Phosphoprotein Reference proteome Secreted Signal | MTGCGRRSGW | MTGCGRRSGWLPPLRLLLLPLLLGGPGVGAAQLAALYSASDPLTLLQADTVRSTVLNSPSAWAVEFFASWCGHCIAFAPTWKALAKDIKDWRPALNLAALNCADETNNAVCRDFNIAGFPSVRFFKAFSKNSTGTTLPVAGANVQMLRERLIDALESHHDTWPSACPPLEPVKPKEIDTFFARNNQEYLVLIFEQENSYLGREVTLDLSQHHDLVVRRVLSTEANVVRKFGVADFPSCYLLFRNGSVSRVPVLVESRRFYTAYLQRLSEVTREGTPTPAVPTISDQIAPTVWKFADRSKIYMADLESALHYILRVEVGRF... | extracellular matrix assembly negative regulation of macroautophagy extracellular exosome; extracellular space; Golgi membrane; intercellular bridge FAD binding flavin-dependent sulfhydryl oxidase activity protein disulfide isomerase activity Cavia porcellus Disulfide bond FAD Flavoprotein Glycoprotein Oxidoreductase P... |
negative regulation of protein autophosphorylation nervous system development transmembrane receptor protein tyrosine kinase signaling pathway | external side of plasma membrane; receptor complex | glial cell-derived neurotrophic factor receptor activity | Mus musculus | Alternative splicing Cell membrane Glycoprotein GPI-anchor Lipoprotein Membrane Receptor Reference proteome Signal | MILANAFCLF | MILANAFCLFFFLDETLRSLASPSSPQGSELHGWRPQVDCVRANELCAAESNCSSRYRTLRQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEGEEFYEASPYEPVTSRLSDIFRLASIFSGTGADPVVSAKSNHCLDAAKACNLNDNCKKLRSSYISICNREISPTERCNRRKCHKALRQFFDRVPSEYTYRMLFCSCQDQACAERRRQTILPSCSYEDKEKPNCLDLRSLCRTDHLCRSRLADFHANCRASYRTITSCPADNYQACLGSYAGMIGFDMTPNYVDSNPTGIVVS... | negative regulation of protein autophosphorylation nervous system development transmembrane receptor protein tyrosine kinase signaling pathway external side of plasma membrane; receptor complex glial cell-derived neurotrophic factor receptor activity Mus musculus Alternative splicing Cell membrane Glycoprotein GPI-anch... |
cellular response to interferon-alpha cilium assembly immune system development regulation of gene expression response to UV smoothened signaling pathway | cytoplasm; cytosol; nuclear body; nucleoplasm; nucleus; ribonucleoprotein complex | metal ion binding misfolded RNA binding RNA binding U2 snRNA binding | Mus musculus | Acetylation Cilium biogenesis/degradation Cytoplasm Direct protein sequencing Metal-binding Phosphoprotein Reference proteome Repeat Ribonucleoprotein RNA-binding | MEGSANQLQP | MEGSANQLQPLSETQVVNSEGGCVWQVTDMNRLRRFLCFGSEGGTYYIKEQKLGLENAEALIRLIEDGRGCEVIQEIKSFSQEGRTAKQEPLLFALAVCSQCADINTKQAAFKAVPEVCRIPTHLFTFIQFKKDLKESMKCGMWGRALRKAVADWYNEKGGMAVALVVTKYKQRNGWSHKDLLRLSHLKPSSEGLAIVTKYITKGWKEVHEEYKEKALSVEAEKLLKYLEAVEKVKRTKDDLEVIHLIEEHQLVREHLLTNHLKSKEVWKALLQEMPLTALLRNLGKMTANSVLEPGNSEVSLICEKLSNEKLLKKARIH... | cellular response to interferon-alpha cilium assembly immune system development regulation of gene expression response to UV smoothened signaling pathway cytoplasm; cytosol; nuclear body; nucleoplasm; nucleus; ribonucleoprotein complex metal ion binding misfolded RNA binding RNA binding U2 snRNA binding Mus musculus Ac... |
brown fat cell differentiation cell cycle G protein-coupled receptor signaling pathway maternal process involved in female pregnancy negative regulation of cardiac muscle hypertrophy negative regulation of cell growth involved in cardiac muscle cell development negative regulation of G protein-coupled receptor signalin... | cytoplasm; cytoplasmic side of plasma membrane; cytosol; nucleolus; nucleus; plasma membrane | adenylate cyclase inhibitor activity beta-tubulin binding G-protein alpha-subunit binding GTPase activator activity | Mus musculus | Cell cycle Cell membrane Cytoplasm GTPase activation Membrane Nucleus Phosphoprotein Reference proteome Signal transduction inhibitor Translation regulation | MQSAMFLAVQ | MQSAMFLAVQHDCVPMDKSAGNGPKVEEKREKMKRTLLKDWKTRLSYFLQNSSAPGKPKTGKKSKQQTFIKPSPEEAQLWAEAFDELLASKYGLAAFRAFLKSEFCEENIEFWLACEDFKKTKSPQKLSSKARKIYTDFIEKEAPKEINIDFQTKSLIAQNIQEATSGCFTTAQKRVYSLMENNSYPRFLESEFYQDLCKKPQITTEPHAT | brown fat cell differentiation cell cycle G protein-coupled receptor signaling pathway maternal process involved in female pregnancy negative regulation of cardiac muscle hypertrophy negative regulation of cell growth involved in cardiac muscle cell development negative regulation of G protein-coupled receptor signalin... |
in utero embryonic development positive regulation of transcription by RNA polymerase III positive regulation of transcription elongation by RNA polymerase II snRNA transcription by RNA polymerase II snRNA transcription by RNA polymerase III transcription elongation by RNA polymerase II | Cajal body; cytosol; euchromatin; histone locus body; nuclear body; nuclear speck; nucleoplasm; transcription elongation factor complex | cis-regulatory region sequence-specific DNA binding phosphatase binding | Mus musculus | Acetylation Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MAALKEARSY | MAALKEARSYGLSCGRVSDGSRVSVFHVKLTDSALKAFESYRAHQDSVSLRPSIRFEGSQGHISIPQPDCPEEVRAFSFYLSNIGRDSPQGSFDCIQQYVSSYGDVHLDCLGSIQDKVTVCATDDSYQKARQSMAQAEEETRSRSAIVIKAGGRYMGKKVQFRKPAPGAADAVPSRKRATPINLASAIRKSSGSGASSVVQRPFRDRVLHLLALRPYRKAELLLRLQKDGLTQADKDTLDSLLQQVASVNPKDGTCTLQDCMYKSLQKDWPGYSEGDRQLLKRMLMRKLCQPQNATTDSSPPREHGRSASPSQKRPTDFI... | in utero embryonic development positive regulation of transcription by RNA polymerase III positive regulation of transcription elongation by RNA polymerase II snRNA transcription by RNA polymerase II snRNA transcription by RNA polymerase III transcription elongation by RNA polymerase II Cajal body; cytosol; euchromatin... |
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway cellular response to glucocorticoid stimulus glucose homeostasis neuropeptide signaling pathway positive regulation of cytokinesis regulation of insulin secretion | neuron projection; plasma membrane | neuropeptide binding somatostatin receptor activity | Mus musculus | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MEPLSLTSTP | MEPLSLTSTPSWNASAASSSSHNWSLVDPVSPMGARAVLVPVLYLLVCTVGLGGNTLVIYVVLRYAKMKTVTNVYILNLAVADVLFMLGLPFLATQNAVSYWPFGSFLCRLVMTLDGINQFTSIFCLMVMSVDRYLAVVHPLRSARWRRPRVAKLASAAVWVFSLLMSLPLLVFADVQEGWGTCNLSWPEPVGLWGAAFITYTSVLGFFGPLLVICLCYLLIVVKVKAAGMRVGSSRRRRSERKVTRMVVVVVLVFVGCWLPFFIVNIVNLAFTLPEEPTSAGLYFFVVVLSYANSCANPLLYGFLSDNFRQSFRKALCL... | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway cellular response to glucocorticoid stimulus glucose homeostasis neuropeptide signaling pathway positive regulation of cytokinesis regulation of insulin secretion neuron projection; plasma membrane neuropeptide binding somatostatin receptor activ... |
cell adhesion fibronectin fibril organization hyaluronan metabolic process negative regulation of BMP signaling pathway negative regulation of inflammatory response negative regulation of neutrophil chemotaxis negative regulation of osteoblast differentiation negative regulation of osteoclast differentiation ovarian cu... | extracellular region; extracellular space | calcium ion binding carboxylesterase activity fibronectin binding hyaluronic acid binding | Mus musculus | Calcium Cell adhesion Disulfide bond Glycoprotein Hydrolase Metal-binding Reference proteome Secreted Signal | MVVLLCLCVL | MVVLLCLCVLLWEEAHGWGFKNGIFHNSIWLEQAAGVYHREARAGRYKLTYAEAKAVCEFEGGRLATYKQLEAARKIGFHVCAAGWMAKGRVGYPIVKPGPNCGFGKTGIIDYGIRLNRSERWDAYCYNPHAKECGGVFTDPKRIFKSPGFPNEYDDNQVCYWHIRLKYGQRIHLSFLDFDLEHDPGCLADYVEIYDSYDDVHGFVGRYCGDELPEDIISTGNVMTLKFLSDASVTAGGFQIKYVTVDPASKSSQAKNTSTTGNKKFLPGRFSHL | cell adhesion fibronectin fibril organization hyaluronan metabolic process negative regulation of BMP signaling pathway negative regulation of inflammatory response negative regulation of neutrophil chemotaxis negative regulation of osteoblast differentiation negative regulation of osteoclast differentiation ovarian cu... |
apoptotic process cellular response to tumor necrosis factor necroptotic process negative regulation of apoptotic process negative regulation of necroptotic process negative regulation of phosphorylation negative regulation of reactive oxygen species metabolic process positive regulation of protein polyubiquitination p... | cytoplasm; cytosol; nucleoplasm; nucleus; protein-containing complex | cysteine-type endopeptidase inhibitor activity involved in apoptotic process metal ion binding protein-containing complex binding transferase activity ubiquitin protein ligase activity ubiquitin-protein transferase activity | Mus musculus | Apoptosis Cytoplasm Metal-binding Nucleus Phosphoprotein Reference proteome Repeat Transferase Ubl conjugation Ubl conjugation pathway Zinc Zinc-finger | MVQDSAFLAK | MVQDSAFLAKLMKSADTFELKYDFSCELYRLSTYSAFPRGVPVSERSLARAGFYYTGANDKVKCFCCGLMLDNWKQGDSPMEKHRKLYPSCNFVQTLNPANSLEASPRPSLPSTAMSTMPLSFASSENTGYFSGSYSSFPSDPVNFRANQDCPALSTSPYHFAMNTEKARLLTYETWPLSFLSPAKLAKAGFYYIGPGDRVACFACDGKLSNWERKDDAMSEHQRHFPSCPFLKDLGQSASRYTVSNLSMQTHAARIRTFSNWPSSALVHSQELASAGFYYTGHSDDVKCFCCDGGLRCWESGDDPWVEHAKWFPRCEYL... | apoptotic process cellular response to tumor necrosis factor necroptotic process negative regulation of apoptotic process negative regulation of necroptotic process negative regulation of phosphorylation negative regulation of reactive oxygen species metabolic process positive regulation of protein polyubiquitination p... |
apical junction assembly apoptotic process cell adhesion cell cycle cell division cell projection organization epithelial cell migration intracellular signal transduction positive regulation of cytokinesis positive regulation of mitotic cell cycle positive regulation of viral genome replication protein phosphorylation ... | apical junction complex; cleavage furrow; cytoplasm; cytoskeleton; lamellipodium; midbody; nucleus; perinuclear region of cytoplasm | ATP binding diacylglycerol-dependent serine/threonine kinase activity histone deacetylase binding kinase activity protein serine kinase activity protein serine/threonine kinase activity RNA polymerase binding small GTPase binding | Rattus norvegicus | Acetylation Apoptosis ATP-binding Cell adhesion Cell cycle Cell division Cell junction Cell projection Cilium biogenesis/degradation Coiled coil Cytoplasm Cytoskeleton Direct protein sequencing Kinase Membrane Nucleotide-binding Nucleus Phosphoprotein Reference proteome Repeat Serine/threonine-protein kinase Transcript... | MASNPDRGEI | MASNPDRGEILLTELQVDSRPLPFSENVSAVQKLDFSDTIVQQKLDDVKDRIKREIRKELKIKEGAENLRKVTTDKKNLAYVDNILKKSNKKLEELHHKLQELNAHIVVSDPEDYTDCPRTPDTPNSDSRSSTSNNRRLMALQKQLDIELKVKQGAENMIQMYSNGPSKDRKLHGTAQQLLQDNKTKIEVIRMHILQAVLTNELAFDNAKPVISPLELRNGRIIEHHFRIEFAVAEGAKNVMKLLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNELPKNHPKSSVVIEELSLVASPTLSPRQSMLSTQNQYS... | apical junction assembly apoptotic process cell adhesion cell cycle cell division cell projection organization epithelial cell migration intracellular signal transduction positive regulation of cytokinesis positive regulation of mitotic cell cycle positive regulation of viral genome replication protein phosphorylation ... |
axon extension axonogenesis brain development central nervous system projection neuron axonogenesis dendrite morphogenesis forebrain development negative regulation of protein localization to nucleus neuron migration neuron projection morphogenesis phosphorylation protein localization to nucleus response to virus | axon; growth cone; postsynaptic density | ATP binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity | Rattus norvegicus | ATP-binding Developmental protein Differentiation Kinase Neurogenesis Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MLELIEVNGT | MLELIEVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRISQHGGSSTSLSSTKVCSSMDENDGPGEEESDEGFQIPATITERYKVGRTIGDGNFAVVKECIERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELINMM... | axon extension axonogenesis brain development central nervous system projection neuron axonogenesis dendrite morphogenesis forebrain development negative regulation of protein localization to nucleus neuron migration neuron projection morphogenesis phosphorylation protein localization to nucleus response to virus axon;... |
bone mineralization cellular response to peptide cellular response to starvation circadian rhythm negative regulation of DNA-templated transcription positive regulation of osteoclast differentiation positive regulation of transcription by RNA polymerase II regulation of circadian rhythm regulation of DNA-templated tran... | nucleus | core promoter sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding... | Rattus norvegicus | Biological rhythms DNA-binding Metal-binding Nucleus Phosphoprotein Reference proteome Repeat Repressor Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | MLNFGASLQQ | MLNFGASLQQASEGKMELISEKSKEGAHPWDKAEQSDFEAVEALMSMSCDWKSHFKKYLENRPVTPVSDTSEEDSLLPGTPDLQTVPAFCLTPPYSPSDFEPSQGSNLTAPAPPTGHFRSLSDAAKPPSIAPFKEEEKSPLAAPPLPKAQATSVIRHTADAQLCNHQSCPVKAASILNYQDNSFRRRTHINVEATRKNIPCAAVSPNRPKPEPSTAANGAEKAGTAPYDFAVPSSETVICRSSQPAPTSPVQKSVLMSSPTVSTGGVPPLPVICQMVPLPANNSLVTTVVPSSPPSQPPAVCSPVLFMGTQVPKGTVMFV... | bone mineralization cellular response to peptide cellular response to starvation circadian rhythm negative regulation of DNA-templated transcription positive regulation of osteoclast differentiation positive regulation of transcription by RNA polymerase II regulation of circadian rhythm regulation of DNA-templated tran... |
phosphatidylserine biosynthetic process | endoplasmic reticulum membrane; membrane | L-serine-phosphatidylethanolamine phosphatidyltransferase activity | Cricetulus griseus | Endoplasmic reticulum Glycoprotein Lipid biosynthesis Lipid metabolism Membrane Phospholipid biosynthesis Phospholipid metabolism Phosphoprotein Transferase Transmembrane Transmembrane helix | MRRAERRVAG | MRRAERRVAGGSGSGSPLLEGRRSTESEVYDDGTNTFFWRAHTLTVLFILTCSLGYVTLLEETPQDTAYNTKRGIVASILVFLCFGVTQAKDGPFSRPHPAYWRFWLCVSVVYELFLIFILFQTVQDGRQFLKYVDPRLGVPLPERDYGGNCLIYDADNKTDPFHNIWDKLDGFVPAHFIGWYLKTLMIRDWWMCMIISVMFEFLEYSLEHQLPNFSECWWDHWIMDVLICNGLGIYCGMKTLEWLSLKTYKWQGLWNIPTYKGKMKRIAFQFTPYSWVRFEWKPASSLHRWLAVCGIILVFLLAELNTFYLKFVLWMPP... | phosphatidylserine biosynthetic process endoplasmic reticulum membrane; membrane L-serine-phosphatidylethanolamine phosphatidyltransferase activity Cricetulus griseus Endoplasmic reticulum Glycoprotein Lipid biosynthesis Lipid metabolism Membrane Phospholipid biosynthesis Phospholipid metabolism Phosphoprotein Transfe... |
adenylate cyclase-inhibiting serotonin receptor signaling pathway behavior bone remodeling cellular response to alkaloid cellular response to temperature stimulus cellular response to xenobiotic stimulus chemical synaptic transmission G protein-coupled receptor internalization negative regulation of serotonin secretion... | endoplasmic reticulum; G protein-coupled serotonin receptor complex; plasma membrane; presynaptic membrane; serotonergic synapse | G protein-coupled serotonin receptor activity serotonin binding | Cavia porcellus | Behavior Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MGNPEASCTP | MGNPEASCTPPAVLGSQTGLPHANVSAPPNNCSAPSHIYQDSIALPWKVLLVVLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAFTDLLVSILVMPISTMYTVTGRWTLGQALCDFWLSSDITCCTASIMHLCVIALDRYWAITDAVGYSAKRTPRRAAGMIALVWVFSICISLPPFFWRQAKAEEEVLDCLVNTDHVLYTVYSTGGAFYLPTLLLIALYGRIYVEARSRILKQTPNKTGKRLTRAQLITDSPGSTSSVTSINSRAPEVPCDSGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGVILG... | adenylate cyclase-inhibiting serotonin receptor signaling pathway behavior bone remodeling cellular response to alkaloid cellular response to temperature stimulus cellular response to xenobiotic stimulus chemical synaptic transmission G protein-coupled receptor internalization negative regulation of serotonin secretion... |
B cell differentiation positive regulation of transcription by RNA polymerase II regulation of apoptotic process regulation of B cell differentiation regulation of B cell proliferation regulation of lymphocyte differentiation regulation of transcription by RNA polymerase II response to bacterium T cell differentiation | cytoplasm; cytosol; nucleoplasm; nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity histone deacetylase binding identical protein binding metal ion binding promoter-specific chromatin binding protein heterodimerization activity protein homodimerization activity RNA polymerase II cis-regul... | Mus musculus | B-cell activation Cytoplasm DNA-binding Isopeptide bond Metal-binding Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | MEDIQPTVEL | MEDIQPTVELKSTEEQPLPTESPDALNDYSLPKPHEIENVDSREAPANEDEDAGEDSMKVKDEYSDRDENIMKPEPMGDAEESEMPYSYAREYSDYESIKLERHVPYDNSRPTGGKMNCDVCGLSCISFNVLMVHKRSHTGERPFQCNQCGASFTQKGNLLRHIKLHTGEKPFKCHLCNYACQRRDALTGHLRTHSVEKPYKCEFCGRSYKQRSSLEEHKERCRAFLQNPDLGDAASVEARHIKAEMGSERALVLDRLASNVAKRKSSMPQKFIGEKRHCFDANYNPGYMYEKENEMMQTRMMDQAINNAISYLGAEALR... | B cell differentiation positive regulation of transcription by RNA polymerase II regulation of apoptotic process regulation of B cell differentiation regulation of B cell proliferation regulation of lymphocyte differentiation regulation of transcription by RNA polymerase II response to bacterium T cell differentiation ... |
cellular response to insulin stimulus insulin receptor signaling pathway intracellular glucose homeostasis negative regulation of cell migration involved in sprouting angiogenesis negative regulation of MAPK cascade phosphatidylinositol 3-kinase/protein kinase B signal transduction phosphatidylinositol phosphate biosyn... | focal adhesion; nucleus; phosphatidylinositol 3-kinase complex; phosphatidylinositol 3-kinase complex, class IA | 1-phosphatidylinositol-3-kinase regulator activity phosphatidylinositol 3-kinase regulatory subunit binding phosphotyrosine residue binding protein heterodimerization activity protein phosphatase binding receptor tyrosine kinase binding | Mus musculus | 3D-structure Phosphoprotein Protein transport Reference proteome Repeat SH2 domain SH3 domain Stress response Transport Ubl conjugation | MAGAEGFQYR | MAGAEGFQYRAVYPFRRERPEDLELLPGDLLVVSRVALQALGVADGGERCPHNVGWMPGFNERTRQRGDFPGTYVEFLGPVALARPGPRPRGPRPLPARPLDGSSESGHILPDLAEQFSPPDPAPPILVKLVEAIEQAELDSECYSKPELPATRTDWSLSDLEQWDRTALYDAVKGFLLALPAAVVTPEAAAEAYRALREVAGPVGLVLEPPTLPLHQALTLRFLLQHLGRVARRAPSPDTAVHALASAFGPLLLRIPPSGGEGDGSEPVPDFPVLLLERLVQEHVEEQDAAPPALPPKPSKAKPAPTALANGGSPPSLQ... | cellular response to insulin stimulus insulin receptor signaling pathway intracellular glucose homeostasis negative regulation of cell migration involved in sprouting angiogenesis negative regulation of MAPK cascade phosphatidylinositol 3-kinase/protein kinase B signal transduction phosphatidylinositol phosphate biosyn... |
cell cycle intracellular signal transduction myoblast differentiation negative regulation of cell cycle phosphorylation | cytoplasm; mitochondrion; nucleoplasm; nucleus | ATP binding magnesium ion binding MAP kinase activity protein serine kinase activity protein serine/threonine kinase activity | Mus musculus | ATP-binding Cell cycle Cytoplasm Kinase Magnesium Metal-binding Mitochondrion Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Stress response Transcription Transcription regulation Transferase Ubl conjugation | MSSPPPARKG | MSSPPPARKGFYRQEVTKTAWEVRAVYQDLQPVGSGAYGAVCSAVDSRTGNKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDESLDDFTDFYLVMPFMGTDLGKLMKHETLSEDRIQFLVYQMLKGLKYIHAAGVIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKILFKGNDHLDQLKEIMKITGTPPPEFVQKLQSAEAKNYMEGLPELEKKDFASVLTNASPQAVNLLERMLVLDAEQRVTAAEALTHPYFESLRDTEDE... | cell cycle intracellular signal transduction myoblast differentiation negative regulation of cell cycle phosphorylation cytoplasm; mitochondrion; nucleoplasm; nucleus ATP binding magnesium ion binding MAP kinase activity protein serine kinase activity protein serine/threonine kinase activity Mus musculus ATP-binding Ce... |
protein O-linked glycosylation protein O-linked glycosylation via serine protein O-linked glycosylation via threonine | extracellular region; Golgi apparatus; Golgi cisterna membrane; perinuclear region of cytoplasm | carbohydrate binding manganese ion binding polypeptide N-acetylgalactosaminyltransferase activity | Mus musculus | 3D-structure Disulfide bond Glycoprotein Glycosyltransferase Golgi apparatus Lectin Manganese Membrane Metal-binding Reference proteome Secreted Signal-anchor Transferase Transmembrane Transmembrane helix | MRKFAYCKVV | MRKFAYCKVVLATSLVWVLLDMFLLLYFSECNKCEEKQERGLPAGDVLELVQKPHEGPGEMGKPVVIPKEDQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKTKVYPDNLPTTSVVIVFHNEAWSTLLRTVHSVINRSPRHMIEEIVLVDDASERDFLKRPLESYVKKLKVPVHVIRMEQRSGLIRARLKGAAVSRGQVITFLDAHCECTAGWLEPLLARIKHDRRTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGEN... | protein O-linked glycosylation protein O-linked glycosylation via serine protein O-linked glycosylation via threonine extracellular region; Golgi apparatus; Golgi cisterna membrane; perinuclear region of cytoplasm carbohydrate binding manganese ion binding polypeptide N-acetylgalactosaminyltransferase activity Mus musc... |
fatty acid catabolic process fatty acid metabolic process monoacylglycerol catabolic process positive regulation of vasoconstriction | endoplasmic reticulum membrane; Golgi membrane; organelle membrane | acylglycerol lipase activity amidase activity fatty acid amide hydrolase activity hydrolase activity, acting on ester bonds identical protein binding lipid binding phospholipid binding | Mus musculus | Endoplasmic reticulum Golgi apparatus Hydrolase Lipid degradation Lipid metabolism Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix | MVLSEVWTAL | MVLSEVWTALSGLSGVCLACSLLSAAVVLRWTRSQTARGAVTRARQKQRAGLETMDKAVQRFRLQNPDLDSEALLALPLLQLVQKLQSGELSPEAVLFTYLGKAWEVNKGTNCVTSYLTDCETQLSQAPRQGLLYGVPVSLKECFSYKGHASTLGLSLNEGVTSESDCVVVQVLKLQGAVPFVHTNVPQSMLSYDCSNPLFGQTMNPWKPSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSAFCGICGLKPTGNRLSKSGLKSCVYGQTAVQLSVGPMARDVDSLALCMKALLCEDLFRLDSTIPPLPFREEIYR... | fatty acid catabolic process fatty acid metabolic process monoacylglycerol catabolic process positive regulation of vasoconstriction endoplasmic reticulum membrane; Golgi membrane; organelle membrane acylglycerol lipase activity amidase activity fatty acid amide hydrolase activity hydrolase activity, acting on ester bo... |
protein maturation by protein folding protein targeting to mitochondrion regulation of protein kinase A signaling xenobiotic metabolic process | aryl hydrocarbon receptor complex; cytosol; membrane; plasma membrane | aryl hydrocarbon receptor binding GAF domain binding peptidyl-prolyl cis-trans isomerase activity transcription coregulator activity unfolded protein binding | Mus musculus | 3D-structure Cytoplasm Direct protein sequencing Phosphoprotein Reference proteome Repeat TPR repeat | MADLIARLRE | MADLIARLREDGIQKRVIQEGRGELPDFQDGTKATFHFRTLHSDNEGSVIDDSRTRGKPMELIVGKKFKLPVWETIVCTMREGEIAQFLCDIKHVVLYPLVAKSLRNIAEGKDPLEGQRHCCGIAQMHEHSSLGHADLDALQQNPQPLIFHIEMLKVESPGTYQQDPWAMTDEEKAKAVPVIHQEGNRLYREGQVKEAAAKYYDAIACLKNLQMKEQPGSPDWIQLDLQITPLLLNYCQCKLVAQEYYEVLDHCSSILNKYDDNVKAYFKRGKAHAAVWNAQEAQADFAKVLELDPALAPVVSRELRALETRIRQKDEED... | protein maturation by protein folding protein targeting to mitochondrion regulation of protein kinase A signaling xenobiotic metabolic process aryl hydrocarbon receptor complex; cytosol; membrane; plasma membrane aryl hydrocarbon receptor binding GAF domain binding peptidyl-prolyl cis-trans isomerase activity transcrip... |
cartilage condensation common myeloid progenitor cell proliferation dorsal spinal cord development olfactory bulb interneuron differentiation pattern specification process regulation of cell differentiation regulation of gene expression | nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific sequence-specific double-stranded DNA binding | Mus musculus | Developmental protein Differentiation DNA-binding Homeobox Neurogenesis Nucleus Reference proteome Transcription Transcription regulation | MMDGRLLEHP | MMDGRLLEHPHAQFGGSLGGVVGFPYPLGHHHVYELAGHQLQSAAAAAAAASVPFSIDGLLSGSCAAAAASVVNPTPLLPAACGVAGESQPFKLADSGDPDKESPGCKRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKKENTKKGPGRPAHNSHPTTCSGEPMDPEEIARKELEKMEKKKRKHEKKLLKSQSRHLHSPGGLSLHSAPSSDSDSGGGGLSPEPPEPPPPTAAAKGPGAHGSGIAGSAPVPPGEPPAPGTCDPAFYPSQRSGAGSQPRLGRPADKDTVPCGPGA... | cartilage condensation common myeloid progenitor cell proliferation dorsal spinal cord development olfactory bulb interneuron differentiation pattern specification process regulation of cell differentiation regulation of gene expression nucleus DNA-binding transcription factor activity, RNA polymerase II-specific seque... |
positive regulation of transcription by RNA polymerase II positive regulation of transcription initiation by RNA polymerase II transcription by RNA polymerase II transcription initiation at RNA polymerase II promoter | cytoplasm; cytosol; nucleus; transcription factor TFIIA complex; transcription factor TFIID complex; transcription preinitiation complex | DNA binding protein heterodimerization activity RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase II general transcription initiation factor activity RNA polymerase II general transcription initiation factor binding RNA polymerase II-specific DNA-binding transcription factor binding TBP-class... | Rattus norvegicus | Acetylation Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MANSANTNTV | MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASSITSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQIPAAGQQQPQAQPAQQQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDD... | positive regulation of transcription by RNA polymerase II positive regulation of transcription initiation by RNA polymerase II transcription by RNA polymerase II transcription initiation at RNA polymerase II promoter cytoplasm; cytosol; nucleus; transcription factor TFIIA complex; transcription factor TFIID complex; tr... |
(R)-carnitine transmembrane transport acetylcholine transport acyl carnitine transmembrane transport dopamine transport dopamine uptake epinephrine transport establishment or maintenance of transmembrane electrochemical gradient metanephric proximal tubule development monoamine transport monoatomic cation transmembrane... | apical plasma membrane; basal plasma membrane; basolateral plasma membrane; lateral plasma membrane; plasma membrane; presynapse | (R)-carnitine transmembrane transporter activity acetylcholine transmembrane transporter activity dopamine:sodium symporter activity identical protein binding monoamine transmembrane transporter activity neurotransmitter transmembrane transporter activity norepinephrine:sodium symporter activity organic anion transmemb... | Mus musculus | Cell membrane Glycoprotein Ion transport Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport | MPTVDDVLEH | MPTVDDVLEHVGEFGWFQKQAFLLLCLISASLAPIYVGIVFLGFTPDHHCRSPGVAELSQRCGWSPAEELNYTVPGLGSAGEASFLSQCMKYEVDWNQSTLDCVDPLSSLAANRSHLPLSPCEHGWVYDTPGSSIVTEFNLVCGDAWKVDLFQSCVNLGFFLGSLVVGYIADRFGRKLCLLVTTLVTSLSGVLTAVAPDYTSMLLFRLLQGMVSKGSWVSGYTLITEFVGSGYRRTTAILYQVAFTVGLVGLAGVAYAIPDWRWLQLAVSLPTFLFLLYYWFVPESPRWLLSQKRTTQAVRIMEQIAQKNRKVPPADLKM... | (R)-carnitine transmembrane transport acetylcholine transport acyl carnitine transmembrane transport dopamine transport dopamine uptake epinephrine transport establishment or maintenance of transmembrane electrochemical gradient metanephric proximal tubule development monoamine transport monoatomic cation transmembrane... |
establishment of epithelial cell polarity Golgi vesicle transport positive regulation of cell adhesion regulation of ARF protein signal transduction | adherens junction; bicellular tight junction; cytoplasm; cytosol; nucleoplasm; plasma membrane; ruffle | guanyl-nucleotide exchange factor activity phosphatidylinositol-3,4,5-trisphosphate binding | Mus musculus | 3D-structure Cell junction Cell membrane Coiled coil Cytoplasm Guanine-nucleotide releasing factor Lipid-binding Membrane Reference proteome Tight junction | MDEGGGGEGG | MDEGGGGEGGSVPEDLSLEEREELLDIRRRKKELIDDIERLKYEIAEVMTEIDNLTSVEESKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERDDFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVED... | establishment of epithelial cell polarity Golgi vesicle transport positive regulation of cell adhesion regulation of ARF protein signal transduction adherens junction; bicellular tight junction; cytoplasm; cytosol; nucleoplasm; plasma membrane; ruffle guanyl-nucleotide exchange factor activity phosphatidylinositol-3,4,... |
animal organ morphogenesis placenta development positive regulation of apoptotic process regulation of cell migration regulation of embryonic development regulation of gene expression regulation of glycogen metabolic process regulation of spongiotrophoblast cell proliferation | cytoplasm; membrane | phosphatidylinositol phosphate binding | Mus musculus | Cytoplasm Membrane Phosphoprotein Reference proteome | MASKIVMSSK | MASKIVMSSKTVKTSDEILCEGELEKRSDSLFQVWKKKRCVLTADRLRLFSGKTSPAKELFFHSILKVDCVEHTSKYVYFTIVTNYYKEIDFRCTVESCWNAAITMALIDFQNRRALQDFPRYRYQRSESEMPSEPGEQSALGP | animal organ morphogenesis placenta development positive regulation of apoptotic process regulation of cell migration regulation of embryonic development regulation of gene expression regulation of glycogen metabolic process regulation of spongiotrophoblast cell proliferation cytoplasm; membrane phosphatidylinositol ph... |
blood coagulation cell morphogenesis eye pigmentation gene expression inflammatory response intracellular transport intracellular zinc ion homeostasis lung development lung morphogenesis lysosome organization melanocyte differentiation melanosome assembly organelle organization pigmentation platelet dense granule organ... | BLOC-3 complex; cytoplasm; cytoplasmic vesicle | guanyl-nucleotide exchange factor activity protein dimerization activity | Mus musculus | Albinism Guanine-nucleotide releasing factor Reference proteome Repeat | MKCVLVATEG | MKCVLVATEGAEVLFYWTDEEFAESLRLKLQQSEDEEEELPVLEDQLSTLLAPVIISSMTMLEKLSDTYTCFSTENDNHLYVLHLFGEYLFVAINGDHSESEGDLRRKLCVLKYLFEVHFGLVTVDGQLIRKELRPPDLEERARVWKHFQRLLGTYSYLRDREQSFAVEAVERLIHPQLCEQSIETLERHVVQAINASPERGGEEVLHAFLLVHCKLLAFYSGHGASTLRPADLLALILLVQDLQPSPGTTEEEEEEEDSDSPQRRPKSSQNIPVQQARSQSTSVPTRSSRETDTDSISLPEEYFTPAPSPGDQSSGSLV... | blood coagulation cell morphogenesis eye pigmentation gene expression inflammatory response intracellular transport intracellular zinc ion homeostasis lung development lung morphogenesis lysosome organization melanocyte differentiation melanosome assembly organelle organization pigmentation platelet dense granule organ... |
cholesterol biosynthetic process neutrophil differentiation | cytoplasm; endoplasmic reticulum membrane; membrane; nuclear envelope; nuclear inner membrane; nuclear membrane; nuclear pore; nucleus | chromo shadow domain binding delta14-sterol reductase activity DNA binding NADPH binding nuclear localization sequence binding protein-folding chaperone binding | Rattus norvegicus | Acetylation Cholesterol biosynthesis Cholesterol metabolism Cytoplasm DNA-binding Endoplasmic reticulum Glycoprotein Lipid biosynthesis Lipid metabolism Membrane Nucleus Oxidoreductase Phosphoprotein Receptor Reference proteome Steroid biosynthesis Steroid metabolism Sterol biosynthesis Sterol metabolism Transmembrane ... | MPGRKFADGE | MPGRKFADGEVVRGRWPGSSLYYEVEILSHDSTSQLYTVKYKDGTELELKESDIKPLKSFKQRKSGSTSSSPSRRRSSRSRSRSRSRSPGRAPKGSRRSVSASYQADAKEKEMRREILQVKLTPLVLKPFANSVSVYNGEPEHMEKSATPPKNKQERVILSTEDSYIATQYSLRPRREEVKPKHRVRGTNLVTRGPVPLGTFQVTTPQRRDLEFGGVPGALLIMLGLPACVFLLLLQCAQKDPGLLQFPPPLPALRELWEARVCGVYLLWFFLQALFSLLPVGKVVEGTPLVDGRRLKYRLNGLYAFILTSAAVGTAVFW... | cholesterol biosynthetic process neutrophil differentiation cytoplasm; endoplasmic reticulum membrane; membrane; nuclear envelope; nuclear inner membrane; nuclear membrane; nuclear pore; nucleus chromo shadow domain binding delta14-sterol reductase activity DNA binding NADPH binding nuclear localization sequence bindin... |
negative regulation of receptor internalization negative regulation of transcription by RNA polymerase II positive regulation of cell growth positive regulation of cell migration positive regulation of cell population proliferation positive regulation of epithelial to mesenchymal transition positive regulation of exoso... | adherens junction; cytoplasm; cytoskeleton; cytosol; endoplasmic reticulum membrane; extracellular exosome; focal adhesion; interleukin-5 receptor complex; melanosome; membrane raft; nuclear membrane; nucleoplasm; plasma membrane; presynapse | cell adhesion molecule binding ephrin receptor binding frizzled binding growth factor binding identical protein binding interleukin-5 receptor binding ionotropic glutamate receptor binding neurexin family protein binding phosphatidylinositol-4,5-bisphosphate binding protein heterodimerization activity protein sequester... | Mus musculus | Acetylation Cell junction Cell membrane Cytoplasm Cytoskeleton Endoplasmic reticulum Lipid-binding Membrane Nucleus Phosphoprotein Reference proteome Repeat Secreted | MSLYPSLEDL | MSLYPSLEDLKVDKVIQAQTAYSANPASQAFVLVDASAALPPDGNLYPKLYPELSQYMGLSLNEAEICESMPMVSGAPAQGQLVARPSSVNYMVAPVTGNDAGIRRAEIKQGIREVILCKDQDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDRPFERTVTMHKDSSGHVGFIFKSGKITSIVKDSSAARNGLLTDHHICEINGQNVIGLKDAQIADILSTAGTVVTITIMPTFIFEHIIKRMAPSIMKSLMDHTIPEV | negative regulation of receptor internalization negative regulation of transcription by RNA polymerase II positive regulation of cell growth positive regulation of cell migration positive regulation of cell population proliferation positive regulation of epithelial to mesenchymal transition positive regulation of exoso... |
ceramide biosynthetic process fatty acid biosynthetic process myelin maintenance positive regulation of apoptotic process | endoplasmic reticulum membrane; mitochondrial membrane; mitochondrion | retinol isomerase activity sphingolipid delta-4 desaturase activity | Mus musculus | Endoplasmic reticulum Fatty acid biosynthesis Fatty acid metabolism Isomerase Lipid biosynthesis Lipid metabolism Lipoprotein Membrane Mitochondrion Myristate Oxidoreductase Phosphoprotein Reference proteome Transmembrane Transmembrane helix | MGSRVSREEF | MGSRVSREEFEWVYTDQPHAARRKEILAKYPEIKSLMKPDHNLIWIVAMMLLVQLASFYLVKDLDWKWVIFWSYVFGSCLNHSMTLAIHEISHNFPFGHHKALWNRWFGMFANLSLGVPYSISFKRYHMDHHRYLGADKIDVDIPTDFEGWFFCTTFRKFVWVILQPLFYAFRPLFINPKPITYLEIINTVIQITFDIIIYYVFGVKSLVYMLAATLLGLGLHPISGHFIAEHYMFLKGHETYSYYGPLNLLTFNVGYHNEHHDFPNVPGKNLPMVRKIASEYYDDLPHYNSWIKVLYDFVTDDTISPYSRMKRPPKGNE... | ceramide biosynthetic process fatty acid biosynthetic process myelin maintenance positive regulation of apoptotic process endoplasmic reticulum membrane; mitochondrial membrane; mitochondrion retinol isomerase activity sphingolipid delta-4 desaturase activity Mus musculus Endoplasmic reticulum Fatty acid biosynthesis F... |
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