Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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mRNA processing NAD-cap decapping nuclear-transcribed mRNA catabolic process nucleic acid metabolic process | cytosol; Las1 complex; nucleus | 5'-hydroxyl dinucleotide hydrolase activity GDP binding metal ion binding mRNA 5'-diphosphatase activity phosphodiesterase decapping endonuclease activity RNA binding RNA NAD-cap (NAD-forming) hydrolase activity | Schizosaccharomyces pombe | 3D-structure Hydrolase Metal-binding mRNA processing Nuclease Nucleotide-binding Nucleus Phosphoprotein Reference proteome RNA-binding | MLREFSFYDV | MLREFSFYDVPPAHVPPVSEPLEIACYSLSRDRELLLDDSKLSYYYPPPLFSDLNTGFPNRFHPPKSDPDPISIVKDVLMTKGIQMNSSFLTWRGLITKIMCAPLDPRNHWETYLVMDPTSGIIMMEERTRSETSYANQDRMCYWGYKFEAISTLPEIWDACSRDQIEQRDNQDVVPDEQYCSIVKINIGKSKLILAGEVDCIWDKKPCSAKESDVHSDDGTIEEDASNAENPNLHYVELKTSKKYPLENYGMRKKLLKYWAQSFLLGIGRIIIGFRDDNGILIEMKELFTHQIPKMLRPYFKPNDWTPNRLLVVLEHAL... | mRNA processing NAD-cap decapping nuclear-transcribed mRNA catabolic process nucleic acid metabolic process cytosol; Las1 complex; nucleus 5'-hydroxyl dinucleotide hydrolase activity GDP binding metal ion binding mRNA 5'-diphosphatase activity phosphodiesterase decapping endonuclease activity RNA binding RNA NAD-cap (N... |
gamma-aminobutyric acid catabolic process glutamate metabolic process | cytosol; mitochondrion | 4-aminobutyrate transaminase activity 4-aminobutyrate:2-oxoglutarate transaminase activity pyridoxal phosphate binding | Schizosaccharomyces pombe | Aminotransferase Cytoplasm Pyridoxal phosphate Reference proteome Transferase | MSSTATVTES | MSSTATVTESTHFFPNEPQGPSIKTETIPGPKGKAAAEEMSKYHDISAVKFPVDYEKSIGNYLVDLDGNVLLDVYSQIATIPIGYNNPTLLKAAKSDEVATILMNRPALGNYPPKEWARVAYEGAIKYAPKGQKYVYFQMSGSDANEIAYKLAMLHHFNNKPRPTGDYTAEENESCLNNAAPGSPEVAVLSFRHSFHGRLFGSLSTTRSKPVHKLGMPAFPWPQADFPALKYPLEEHVEENAKEEQRCIDQVEQILTNHHCPVVACIIEPIQSEGGDNHASPDFFHKLQATLKKHDVKFIVDEVQTGVGSTGTLWAHEQW... | gamma-aminobutyric acid catabolic process glutamate metabolic process cytosol; mitochondrion 4-aminobutyrate transaminase activity 4-aminobutyrate:2-oxoglutarate transaminase activity pyridoxal phosphate binding Schizosaccharomyces pombe Aminotransferase Cytoplasm Pyridoxal phosphate Reference proteome Transferase MSS... |
mRNA transport NLS-bearing protein import into nucleus nuclear pore organization rRNA export from nucleus | nuclear envelope; nuclear membrane; nuclear periphery; nuclear pore; nuclear pore central transport channel; nuclear pore nuclear basket | nucleic acid binding phospholipid binding structural constituent of nuclear pore | Schizosaccharomyces pombe | Glycoprotein Membrane mRNA transport Nuclear pore complex Nucleus Phosphoprotein Protein transport Reference proteome Repeat Translocation Transport | MSFGGSGSIT | MSFGGSGSITNRSTLKPLSVDDLRSPSPQKEYRGFRTSVSNIPQEKKFVPSHLSHFGSSQQRRFAPEVSSPLAEPYESSSSFRLSLSSPPSSKFGGPSFGTPKPFLHTNRLGTGSLIEDAPPTQSIYDFSSSRQINALNVGQSSSPFSPVSEKVYDPSFTMSGAPQDSNTSVIVFGFPPELTNQVIAEFSRFGTIISENSLTASSAGFTPSKGPISGNWLQLTYAEPSSAAKAVLSNGMLINDSFMVGCIYSPAEAKEHVPKTLRNSNKDLEMTDASSSETSMSIPVHADAHFQSQSGLGKKVIVQHKNDIFKSSQKHQP... | mRNA transport NLS-bearing protein import into nucleus nuclear pore organization rRNA export from nucleus nuclear envelope; nuclear membrane; nuclear periphery; nuclear pore; nuclear pore central transport channel; nuclear pore nuclear basket nucleic acid binding phospholipid binding structural constituent of nuclear p... |
cell division chromosome segregation negative regulation of septation initiation signaling nuclear envelope organization phosphorylation positive regulation of G2/M transition of mitotic cell cycle | cytoplasm; cytosol; mitotic spindle; mitotic spindle pole body; nuclear envelope; nucleus | ATP binding protein serine kinase activity protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity | Schizosaccharomyces pombe | ATP-binding Cell cycle Cell division Cytoplasm Cytoskeleton Kinase Mitosis Nucleotide-binding Reference proteome Serine/threonine-protein kinase Transferase | MEKYKILECI | MEKYKILECIGHGSFGRIYKVQRLKDGALLAQKEIHFGNITRQEKQYIADEVNILRNLKHPNIVQYCGEELNRSAQVINLYMEYCGHGDLANLIQRYKEEKKRFTEQEVLKFFTQLLLALYRCHYGENAPACDSQWPREIFHPKQSVLHRDIKPANIFLDENNSVKLGDFGLSKLLDNTRVFTQSYVGTPYYMSPEIIRSSPYSAKSDVWALGCVIFEICMLTHPFEGRSYLELQRNICQGNLSCWDHHYSDDVFLLIRHCLEVNSDLRPTTYQLLRSPILSDIRSKLESERVVLEQSDLLHKKHQMLIQLENDLQFREQ... | cell division chromosome segregation negative regulation of septation initiation signaling nuclear envelope organization phosphorylation positive regulation of G2/M transition of mitotic cell cycle cytoplasm; cytosol; mitotic spindle; mitotic spindle pole body; nuclear envelope; nucleus ATP binding protein serine kinas... |
ascospore wall assembly ascospore wall chitin catabolic process | ascospore-type prospore; chitosan layer of spore wall; cytosol; nucleus | chitin binding chitin deacetylase activity identical protein binding metal ion binding | Schizosaccharomyces pombe | Cell wall biogenesis/degradation Chitin-binding Hydrolase Metal-binding Reference proteome Sporulation | MYETRDLTGN | MYETRDLTGNAGKPVDTNPWPNNSKIAVSFVVNYEEGGERSLLYEDEGFETFLTEAGLMPFPNRPVRERSIESCFEYGSRCGFWRILNLFKKHKVPFTCWAIGQAVEKNPVVVGAMEEAGCEVGSHSHRWINYEGVPPETEYEHIKKSVQAIQKASPSNSAPRSWYTGRASLNTRKLVCQVYKDLGLPQPFDSDEYNDDYPYWVADPLASKPGAEDDKGLLIVPYTLEVNDMKYAVAPGFCNSDDFYTYARDAFDVLYEEGLEGAPKMMTIGLHCRLTGRPGRFRGLQKLMEHITSKEGVWVATREQIAQAWSAKHPYKA | ascospore wall assembly ascospore wall chitin catabolic process ascospore-type prospore; chitosan layer of spore wall; cytosol; nucleus chitin binding chitin deacetylase activity identical protein binding metal ion binding Schizosaccharomyces pombe Cell wall biogenesis/degradation Chitin-binding Hydrolase Metal-bindin... |
protein catabolic process in the vacuole zymogen activation | fungal-type vacuole | serine-type carboxypeptidase activity | Schizosaccharomyces pombe | Carboxypeptidase Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Repeat Signal Vacuole Zymogen | MLMKQTFLYF | MLMKQTFLYFLLTCVVSAQFNGYVPPEQNGGDIVVPKDFYEKFGEDFIREQEESSAPLMNPVPERDEAEAPHHPKGHHEFNDDFEDDTALEHPGFKDKLDSFLQPARDFLHTVSDRLDNIFDDDEDEHVREKRPHDSADEDAPRRKHGKCKGKGKHHKGKHAKGKGKKSHPKPEDDSVFFDDERPKHHEFDDEDREFPAHHEPGEHMPPPPMHHKPGEHMPPPPMHHEPGEHMPPPPMHHEPGEHMPPPPMHHEPGEHMPPPPMHHEPGEHMPPPPMHHEPGEHMPPPPMHHEPGEHMPPPPMHHEPGEHMPPPPMHHEP... | protein catabolic process in the vacuole zymogen activation fungal-type vacuole serine-type carboxypeptidase activity Schizosaccharomyces pombe Carboxypeptidase Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Repeat Signal Vacuole Zymogen MLMKQTFLYF MLMKQTFLYFLLTCVVSAQFNGYVPPEQNGGDIVVPKDFYEKFGEDFIREQ... |
cell division dynein-driven meiotic oscillatory nuclear movement phosphatidylinositol phosphate biosynthetic process phosphorylation | cell division site; division septum; nucleus; plasma membrane | 1-phosphatidylinositol-3-phosphate 4-kinase activity 1-phosphatidylinositol-4-phosphate 5-kinase activity ATP binding phospholipid binding | Schizosaccharomyces pombe | ATP-binding Cell cycle Cell division Kinase Membrane Nucleotide-binding Nucleus Phosphoprotein Reference proteome Transferase | MKIDSNGIVN | MKIDSNGIVNPHSITNEIPSYDEKQAVDLNGNAFAPNGTFQKKDLISHKNDFERTMRHDVLHTNPKIEVRSETHIYEPNDSLFKENQDFPSNPTAHSPSSSSNDSVITATGVPDGILRDSPIVSALEPPSSNSSSSPQLQNLKHQLSSPQPSRAPIDRSSSNPVTSSQQPPNDRSTLSSSQKAKRPLKRSYSEKNSSNAEPSGSRSGDRGTNVSTSGSLLDGIPPDIGSASWAEAVKQKRVNMRRRREELDDECVLVGTRVSEGHENYVTAYNMLTGIRVGVSRCQAKMDRELTPADFTARHKFTFDITGNELTPSAKYD... | cell division dynein-driven meiotic oscillatory nuclear movement phosphatidylinositol phosphate biosynthetic process phosphorylation cell division site; division septum; nucleus; plasma membrane 1-phosphatidylinositol-3-phosphate 4-kinase activity 1-phosphatidylinositol-4-phosphate 5-kinase activity ATP binding phospho... |
transcription by RNA polymerase I transcription by RNA polymerase II transcription by RNA polymerase III transcription elongation by RNA polymerase I transcription initiation at RNA polymerase II promoter tRNA transcription by RNA polymerase III | cytosol; nucleolus; nucleus; RNA polymerase I complex; RNA polymerase II, core complex; RNA polymerase III complex | DNA binding DNA-directed 5'-3' RNA polymerase activity zinc ion binding | Schizosaccharomyces pombe | 3D-structure DNA-directed RNA polymerase Metal-binding Nucleus Reference proteome Transcription Zinc | MIIPIRCFSC | MIIPIRCFSCGKVIGDKWDTYLTLLQEDNTEGEALDKLGLQRYCCRRMILTHVDLIEKLLCYNPLSKQKNL | transcription by RNA polymerase I transcription by RNA polymerase II transcription by RNA polymerase III transcription elongation by RNA polymerase I transcription initiation at RNA polymerase II promoter tRNA transcription by RNA polymerase III cytosol; nucleolus; nucleus; RNA polymerase I complex; RNA polymerase II, ... |
negative regulation of cytoplasmic translational initiation in response to stress signaling | cytoplasm; cytosol; nucleus | ATP binding eukaryotic translation initiation factor 2alpha kinase activity protein serine kinase activity | Schizosaccharomyces pombe | ATP-binding Kinase Nucleotide-binding Phosphoprotein Protein synthesis inhibitor Reference proteome Serine/threonine-protein kinase Stress response Transferase | MLGTSTKCSK | MLGTSTKCSKRDCNYAKENISRIMPTIGLGYKQNFEKKTADTQSSCKLLLVALLESFCKHSDQTPEQSKQMFLYVAHSLQNSGIIDFEFSEELEPIRNAYADSLHNLLSKAFRSTLPMSSTKDSKKSRYSSPDGVLAKTASFLSVLSDGGYEDDVMNVKPSVNVLSNRLNHLPVEALESCFPQTTLESSTFADFCEHKDGTGNLSFSNFDSFPTVQRSRYASDFEELELLGKGGYGSVYKARNKFDGVEYALKKIPLRLRSFSTSSNIFRESRTLARLNHPNVIRFFSSWVELLPSSEKQIEEEPLASADETLSQSADID... | negative regulation of cytoplasmic translational initiation in response to stress signaling cytoplasm; cytosol; nucleus ATP binding eukaryotic translation initiation factor 2alpha kinase activity protein serine kinase activity Schizosaccharomyces pombe ATP-binding Kinase Nucleotide-binding Phosphoprotein Protein synth... |
cell wall mannoprotein biosynthetic process chain elongation of O-linked mannose residue protein O-linked mannosylation | endomembrane system; endoplasmic reticulum; endoplasmic reticulum membrane; nuclear membrane | dolichyl-phosphate-mannose-protein mannosyltransferase activity | Schizosaccharomyces pombe | Endoplasmic reticulum Glycoprotein Glycosyltransferase Membrane Nucleus Phosphoprotein Reference proteome Repeat Transferase Transmembrane Transmembrane helix | MDKQSTFQDP | MDKQSTFQDPKEKHRIQRDVKLSRPRKRFSFLDYVVVIFLTVVAFCVRAQRLMNPAKVVFEELRYYNYAVDYVNNKLLMDVYPPLGKLLFSLVAALTGNKYELNTLDEPGQQYPFTDVAYSMRLFTCLLGSLLVPLMYGTVYFPTKSKTAASLAALFVIFDNGLITMSRYIMIEIPALYFMSLTAFYWSVYEAQQKRPFSLRWHTSLLSTGVALGLALSTKLSAMFTFGWLLILAAFHLWNLLGDLSVPMYRIVKHLFSYIFYLIGVPITVYLAVFAVHSHIAYKASVADAFLPPEHRHALAGNRFDDQFADVAYGSLVT... | cell wall mannoprotein biosynthetic process chain elongation of O-linked mannose residue protein O-linked mannosylation endomembrane system; endoplasmic reticulum; endoplasmic reticulum membrane; nuclear membrane dolichyl-phosphate-mannose-protein mannosyltransferase activity Schizosaccharomyces pombe Endoplasmic reti... |
cardiolipin biosynthetic process mitochondrial membrane organization phospholipid homeostasis | mitochondrial inner membrane; mitochondrion | cardiolipin synthase (CMP-forming) cardiolipin synthase activity hydrolase activity | Schizosaccharomyces pombe | Alternative splicing Hydrolase Lipid biosynthesis Lipid metabolism Membrane Mitochondrion Mitochondrion inner membrane Phospholipid biosynthesis Phospholipid metabolism Reference proteome Transferase Transit peptide Transmembrane Transmembrane helix | MLHTINYRSW | MLHTINYRSWHLAARQLGRSTFRKFTTESSTKSPIADVCFAFDSIDGVLIRGGRGLKEGTKTLKFLQKNNIPFILLTNGGGMHESVRAQRLSKTLSVSLTEDDFCQSHTPFRALADKYKHVLVLGGKDNSVRETAEKYGFKSVINELDVIAKLGTPFWPFTSFNEEDIKDAKDFDVTRPIEAVFTYVDPVRLGLDLQLVMELGQSKNGVLGTVSKTANEGPDIYFSNADLIWPNEYPLPRLGQGAFAICCESVFKELTGKDLRNTKYGKPHKLTYDYAKNILMKKHKTLGITNPPKEIFMVGDNPESDIRGANNYGWTSI... | cardiolipin biosynthetic process mitochondrial membrane organization phospholipid homeostasis mitochondrial inner membrane; mitochondrion cardiolipin synthase (CMP-forming) cardiolipin synthase activity hydrolase activity Schizosaccharomyces pombe Alternative splicing Hydrolase Lipid biosynthesis Lipid metabolism Memb... |
glycerol catabolic process glycerol metabolic process phosphorylation | cytoplasm; cytosol | ATP binding glycerone kinase activity triokinase activity | Schizosaccharomyces pombe | ATP-binding Glycerol metabolism Kinase Nucleotide-binding Reference proteome Transferase | MDKHFINDPE | MDKHFINDPEVLVLDGLKSLADMNKTLTVHEEGKFIYFHDYNKKNVSVISGGGAGHEPTHSSFVGKGMLTAAVSGSIFASPSSKQIYTGIKQVESEAGTLVICKNYTGDILHFGMALEKQRTAGKKAELIAVADDVSVGRKKSGKVGRRGLSGTVLVHKIAGAAAARGLPLEAVTTIAKAAIDNLVSIGASLAHVHVPGHEPIAKEDEMKHDEMELGMGIHNEPGCKRISPIPSIDDLIAQMLKQMLDQSDKDRAYVKIEGDDEVVLLMNNLGGLSMLEFSAISHKVKEALAKEYKINPVRIFAGPFTTSLNGLGFGITL... | glycerol catabolic process glycerol metabolic process phosphorylation cytoplasm; cytosol ATP binding glycerone kinase activity triokinase activity Schizosaccharomyces pombe ATP-binding Glycerol metabolism Kinase Nucleotide-binding Reference proteome Transferase MDKHFINDPE MDKHFINDPEVLVLDGLKSLADMNKTLTVHEEGKFIYFHDYNKKNV... |
base-excision repair DNA repair phosphorylation single strand break repair | nucleolus; nucleus | ATP binding ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity double-stranded DNA binding polynucleotide 3'-phosphatase activity | Schizosaccharomyces pombe | ATP-binding DNA damage DNA repair Hydrolase Kinase Multifunctional enzyme Nucleotide-binding Nucleus Phosphoprotein Reference proteome Transferase | MSSKKRKSPP | MSSKKRKSPPQESLTSYFEKSSKSSKKYGSQNKDSDSSSTCLQQKIEIQWSITDSLYIAKYGKLKKTKKFIAFDLDGTLIKTKSGRVFSKDAADWTWWHPSVVPKLKALYQDNYSLVIFSNQNGIPRKPSAGHTFQMKIRAIFESLDLPIVLYAAILKDKFRKPLTGMWNSFLKDVNRSIDLSFIKYVGDAAGRPGDHNSTDLKFAENIGIKFETPEQFFLGHSFVPPNFESFHPKNYLVRNSSSHPYHFKKSEHQEIVVLVGFPSSGKSTLAESQIVTQGYERVNQDILKTKSKCIKAAIEALKKEKSVVIDNTNPTIE... | base-excision repair DNA repair phosphorylation single strand break repair nucleolus; nucleus ATP binding ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity double-stranded DNA binding polynucleotide 3'-phosphatase activity Schizosaccharomyces pombe ATP-binding DNA damage DNA repair Hydrolase Kinase Mul... |
U6 snRNA 3'-end processing | mitochondrion; nucleus | 3'-5'-RNA exonuclease activity lyase activity poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends | Schizosaccharomyces pombe | Hydrolase Lyase Nuclease Nucleus Reference proteome | MSLVCYESSS | MSLVCYESSSSGEDDDETISDNPRMLKVPKLQESFHELYKKKPKTFDSPEFHEGRIRGQKHIEGLWFVQTYLEVDLSKKVKKGIREFLNSQSRFQSLLCSEHNVPRRLHLSISENYRINYSTKNQLVHKWEQYTNNLNYRTLKFRLGKMCLLFNDEKTRMFLAFECKFSDENYKDLISHASDCMKEFTNRNLREDFLLHISFASSLTNEDEYQNWVSQDRESHFFKTMNEIINTKIQKDQFSESFIVDSLKLSIGHLIFTFPFCK | U6 snRNA 3'-end processing mitochondrion; nucleus 3'-5'-RNA exonuclease activity lyase activity poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends Schizosaccharomyces pombe Hydrolase Lyase Nuclease Nucleus Reference proteome MSLVCYESSS MSLVCYESSSSGEDDDETISDNPRMLKVPKLQESFHELYKKKPKTFDS... |
GMP salvage hypoxanthine metabolic process IMP salvage purine ribonucleoside salvage XMP salvage | cytoplasm; endoplasmic reticulum; nucleus | guanine phosphoribosyltransferase activity hypoxanthine phosphoribosyltransferase activity metal ion binding nucleotide binding pentosyltransferase activity xanthine phosphoribosyltransferase activity | Schizosaccharomyces pombe | Endoplasmic reticulum Glycosyltransferase Magnesium Metal-binding Nucleotide-binding Purine salvage Reference proteome Transferase | MDPVRLYYSY | MDPVRLYYSYNDIHKMCAQQAEKILETFRPDVIIAIGGGGFIPARILRTFLKKKGSKNIPIQAIGLSLYEELVSDSPEEVPGLEVKRTQWLDFSTLGMVDLVGKNILIVDEVDDTRTTLHYALRELQRDVAEQAKKLNREGEKTTFGIFVVHNKVKPKNAQLDKEILDKYYFTGCNTPDCWIMYPWEAQDIEEHDSHVAKMGDLKP | GMP salvage hypoxanthine metabolic process IMP salvage purine ribonucleoside salvage XMP salvage cytoplasm; endoplasmic reticulum; nucleus guanine phosphoribosyltransferase activity hypoxanthine phosphoribosyltransferase activity metal ion binding nucleotide binding pentosyltransferase activity xanthine phosphoribosylt... |
cellular detoxification of cadmium ion intracellular cobalt ion homeostasis intracellular zinc ion homeostasis zinc ion import into endoplasmic reticulum zinc ion import into organelle zinc ion transmembrane transport | endoplasmic reticulum membrane; fungal-type vacuole membrane; nuclear membrane | zinc ion transmembrane transporter activity | Schizosaccharomyces pombe | Endoplasmic reticulum Ion transport Membrane Nucleus Reference proteome Transmembrane Transmembrane helix Transport Zinc Zinc transport | MFDLARQTRI | MFDLARQTRIILLLGIDVTFFFIEIITGYAIDSLALIADSFHMLNDIVSLLVALWATRLAHSTSHEPKYTYGWQRAEILGALSNGVFLIALCMFIFMEAIERFIEPPSVSNPTLMFFVGSLGLLSNFVGIFLFHDHGHDHPHTHTAQNYDFPEEDDIESVLPSTIVHRCNTSQQEVSHTHTQVADSATESSPLLSYTGNHNGAGTSKPVNNHGSIEQDAPKQTKKRNLNMHGVFLHVLGDALGNIGVISAALFIKYTDYSWRFLFDPCISILLTFIILFSAIPLCKSAALILLQVAPQSIKLDDVSNLINHLDGVESVHE... | cellular detoxification of cadmium ion intracellular cobalt ion homeostasis intracellular zinc ion homeostasis zinc ion import into endoplasmic reticulum zinc ion import into organelle zinc ion transmembrane transport endoplasmic reticulum membrane; fungal-type vacuole membrane; nuclear membrane zinc ion transmembrane ... |
attachment of meiotic spindle microtubules to meiosis II kinetochore intracellular signal transduction mitotic cell cycle mitotic sister chromatid biorientation phosphorylation | chromosome, subtelomeric region; cytoplasm; cytosol; mating-type region heterochromatin; nucleus; pericentric heterochromatin | ATP binding histone H3T3 kinase activity protein serine kinase activity | Schizosaccharomyces pombe | ATP-binding Cell cycle Chromosome Cytoplasm Kinase Nucleotide-binding Reference proteome Serine/threonine-protein kinase Transferase | MESRSKVKTY | MESRSKVKTYGKNRRYINKDIEIWASLDERPCALKPRNIENFNNQERSDLEHIHSKPKKDSLLSWNILLKKGSYKENELLAKRNQNLVPTVIIPASPRDNASKSVVSKKEVVNLSSSVALSGKPANNSKLDPLHRLLQIVAQEDALPFSQFVKSQTFEIQKIGEASYSEVYQASNADDVPVVWKVIPFGEDGQAQYADVLNEVQISQWIKVDGFANLHQVVVVKGTYPSLLLEEWDRYLMQNGSENDRPDSYSSTQLYCVLCLDHSGTDLEHFELRSWRECWSVFYETLKILSLVETRYEFEHRDLHWGNILIRKADRSE... | attachment of meiotic spindle microtubules to meiosis II kinetochore intracellular signal transduction mitotic cell cycle mitotic sister chromatid biorientation phosphorylation chromosome, subtelomeric region; cytoplasm; cytosol; mating-type region heterochromatin; nucleus; pericentric heterochromatin ATP binding histo... |
actin cytoskeleton organization actin filament organization cell cycle cell division establishment or maintenance of cell polarity microtubule cytoskeleton organization regulation of cell shape regulation of exocytosis regulation of septum digestion after cytokinesis signal transduction small GTPase mediated signal tra... | cell division site; cytosol; nucleus; plasma membrane | GTP binding GTPase activity protein kinase binding | Schizosaccharomyces pombe | Cell cycle Cell division Cell membrane Cell shape GTP-binding Lipoprotein Membrane Methylation Nucleotide-binding Prenylation Reference proteome | MSSCFGSKKK | MSSCFGSKKKPIYRKIVILGDGAAGKTSLLNVFTKGYFPQVYEPTIFENYIHDIFVDGNSIELSLWDTAGQEEYDQLRSLSYSDTHVIMICFAVDSRDSLENVITKWLPEVSSNCPGVKLVLVALKCDLRGADEEQVDHSKIIDYEEGLAAAKKINAVRYLECSAKLNRGVNEAFTEAARVALAAQPRGTKDGADESHGTGCIIA | actin cytoskeleton organization actin filament organization cell cycle cell division establishment or maintenance of cell polarity microtubule cytoskeleton organization regulation of cell shape regulation of exocytosis regulation of septum digestion after cytokinesis signal transduction small GTPase mediated signal tra... |
tRNA methylation tRNA wobble base cytosine methylation | cytoplasm; nucleus | mRNA (cytidine-5-)-methyltransferase activity tRNA (cytidine-5-)-methyltransferase activity tRNA binding | Schizosaccharomyces pombe | Methyltransferase Nucleus Reference proteome RNA-binding S-adenosyl-L-methionine Transferase tRNA processing tRNA-binding | MGKRNKKVTQ | MGKRNKKVTQGKRAYNDKSEIVLENKQFEGYYKKQNLFRGKPNDEFDSFMEYMRKPLPTTFRICGYRHHAFELKNHFEKYYVPSLKNVVHEGQTIPPPTVLPWYPDGLAYIVDAQKDVIRKSPPLKRLQRFLVSENEAGNINRQEAVSMLPPLFLDVEPHHVILDMCAAPGSKTAQLIEAVYKKANIKDAAHDSKNLKSVEGLVIANDADPKRAQMLVHQINRLNSPNILVVNHDASTMPNIYVKGSSPSDGLNVIEEKKILKFDRILADVPCSGDGTFRKNLSLWREWSANSAFSLHPLQLRILIRGLQLLKVGGCLVY... | tRNA methylation tRNA wobble base cytosine methylation cytoplasm; nucleus mRNA (cytidine-5-)-methyltransferase activity tRNA (cytidine-5-)-methyltransferase activity tRNA binding Schizosaccharomyces pombe Methyltransferase Nucleus Reference proteome RNA-binding S-adenosyl-L-methionine Transferase tRNA processing tRNA-... |
mRNA processing regulation of DNA-templated transcription elongation regulation of transcription by RNA polymerase II transcription elongation by RNA polymerase II transcription elongation-coupled chromatin remodeling | chromatin; DSIF complex; nucleus | mRNA binding transcription elongation factor activity | Schizosaccharomyces pombe | 3D-structure mRNA processing Nucleus Phosphoprotein Reference proteome Repeat Transcription | MDTNSPKSID | MDTNSPKSIDKDANSTEVDAAEQDAASVKINSTRASPNGSDLLNDDSEAAKITTNEKQSSPVDSHNESPNDTTINKGEDGNENEVDNVNNNDKKEDEDNVEENEEEADANEEEEEDEEDDEEDEEDEDESGGGRRKRARHDRRNQFLDIEAEVDEDEEELEDEEDEIGREDGFIEEEVGADYVGDDRRHRELDRQRQELQSVDAERLAEEYREKYGRSQTVVGDTSNVPQRLLLPSVNDPNIWAVRCKIGKEKDIVFTIMRKAMDLQYTSSPLEIISAFQRDSLVGYIYVEARKQSHVLDALNGVLNVYTNNMILVPIKE... | mRNA processing regulation of DNA-templated transcription elongation regulation of transcription by RNA polymerase II transcription elongation by RNA polymerase II transcription elongation-coupled chromatin remodeling chromatin; DSIF complex; nucleus mRNA binding transcription elongation factor activity Schizosaccharom... |
phosphorylation positive regulation of transcription by RNA polymerase II positive regulation of transcription initiation by RNA polymerase II | euchromatin; mediator complex; nucleus | ATP binding cyclin-dependent protein serine/threonine kinase activity metal ion binding protein serine kinase activity RNA polymerase II CTD heptapeptide repeat kinase activity transcription coactivator activity | Schizosaccharomyces pombe | Activator ATP-binding Kinase Magnesium Metal-binding Nucleotide-binding Nucleus Reference proteome Repressor Serine/threonine-protein kinase Transcription Transcription regulation Transferase | MKDGYKIIGF | MKDGYKIIGFISSGTYGKVYKAVSSNSNDKRLFAIKKFKAESKQVSSNAQQTGVSQSAIREMMLCREIQHENIVSLVQVLLKDGTISMVFEYAEHDLLQIIHFHSRSRTRQIPPSILKSILWQIINGVAYLHENWIMHRDLKPANIMITATGKVKIGDLGLGRLIRDPILPFYSSDRVVVTIWYRAPELLLGAHDYTPAIDVWAIGCIYGEMLALSPLFKGDEIKMEDKKVVPFQSTQMLRIMELLGTPTEERWPGLKNYPEYYQLSSFEVRYWNNLLPQWYQTVKNRDPQGLDLLMKMLQYDPKSRITAKQALEHVFFT... | phosphorylation positive regulation of transcription by RNA polymerase II positive regulation of transcription initiation by RNA polymerase II euchromatin; mediator complex; nucleus ATP binding cyclin-dependent protein serine/threonine kinase activity metal ion binding protein serine kinase activity RNA polymerase II C... |
heterochromatin formation protein ubiquitination SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process | CLRC complex; cullin-RING ubiquitin ligase complex; cytoplasm; cytosol; nuclear SCF ubiquitin ligase complex; nucleus | cullin family protein binding histone H3K14 ubiquitin ligase activity ubiquitin protein ligase activity zinc ion binding | Schizosaccharomyces pombe | Chromatin regulator Cytoplasm Direct protein sequencing Metal-binding Nucleus Reference proteome Transcription Transcription regulation Ubl conjugation pathway Zinc Zinc-finger | MEDEMQIDKK | MEDEMQIDKKEVEIEQKPPRFEIKKWNAVALWQWDIVVDNCAICRNHIMDLCIECQANTDSAAAQECTVAWGTCNHAFHFHCISRWLNTRNVCPLDNREWEFQRYGH | heterochromatin formation protein ubiquitination SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process CLRC complex; cullin-RING ubiquitin ligase complex; cytoplasm; cytosol; nuclear SCF ubiquitin ligase complex; nucleus cullin family protein binding histo... |
mitotic spindle pole body duplication mitotic spindle pole body insertion into the nuclear envelope mitotic spindle pole body localization mRNA transport nuclear pore organization protein transport spindle pole body localization | cytoplasm; mitotic nuclear bridge midzone; mitotic nuclear bridge midzone membrane domain; mitotic spindle pole body; nuclear envelope; nuclear membrane; nuclear pore; nuclear pore transmembrane ring; spindle pole body | spindle pole body-nuclear membrane anchor activity | Schizosaccharomyces pombe | Cytoplasm Cytoskeleton Membrane mRNA transport Nuclear pore complex Nucleus Protein transport Reference proteome Translocation Transmembrane Transmembrane helix Transport | MVMLRTSFPS | MVMLRTSFPSGSRTKAVRYHTLLRPILQQRFLRACFALLCLCCITSYWFSSGPFISLSFWFLSLVRGFVCFFFMFPYFVMLKSRMSTQKVTKQSLGAQLFYDFSPKSFFLVYLTFAVSVSCLCLFYIKGHASSIRLQWIASPNAYELPSLNERFVYMTYFSHILILALTVEHLYLQRDSPSRPVINVSFFNYIFQNLGWLIRFSFRKSIICCLFTPFSYAILRSYIWRFAALLTSCCRRIAYTKTPPKWPLSLRLLLHSFWMAFIVCLTFQIALLIFRVFLYSGPMIRGKLLSARSNDPNGTLVDGMKTKKKPLTECIAT... | mitotic spindle pole body duplication mitotic spindle pole body insertion into the nuclear envelope mitotic spindle pole body localization mRNA transport nuclear pore organization protein transport spindle pole body localization cytoplasm; mitotic nuclear bridge midzone; mitotic nuclear bridge midzone membrane domain; ... |
regulation of telomere maintenance via telomerase telomere capping telomere maintenance | chromosome, telomeric repeat region; cytosol; nuclear telomere cap complex; nucleus; shelterin complex; telomere cap complex | G-rich strand telomeric DNA binding single-stranded telomeric DNA binding telomerase inhibitor activity | Schizosaccharomyces pombe | 3D-structure Chromosome DNA-binding Nucleus Reference proteome Telomere | MGEDVIDSLQ | MGEDVIDSLQLNELLNAGEYKIGELTFQSIRSSQELQKKNTIVNLFGIVKDFTPSRQSLHGTKDWVTTVYLWDPTCDTSSIGLQIHLFSKQGNDLPVIKQVGQPLLLHQITLRSYRDRTQGLSKDQFRYALWPDFSSNSKDTLCPQPMPRLMKTGDKEEQFALLLNKIWDEQTNKHKNGELLSTSSARQNQTGLSYPSVSFSLLSQITPHQRCSFYAQVIKTWYSDKNFTLYVTDYTENELFFPMSPYTSSSRWRGPFGRFSIRCILWDEHDFYCRNYIKEGDYVVMKNVRTKIDHLGYLECILHGDSAKRYNMSIEKVD... | regulation of telomere maintenance via telomerase telomere capping telomere maintenance chromosome, telomeric repeat region; cytosol; nuclear telomere cap complex; nucleus; shelterin complex; telomere cap complex G-rich strand telomeric DNA binding single-stranded telomeric DNA binding telomerase inhibitor activity Sch... |
ergosterol biosynthetic process | endomembrane system; endoplasmic reticulum; endoplasmic reticulum membrane; membrane | enzyme activator activity metal ion binding steroid binding | Schizosaccharomyces pombe | Endoplasmic reticulum Heme Iron Lipid biosynthesis Lipid metabolism Membrane Metal-binding Phosphoprotein Reference proteome Steroid biosynthesis Steroid metabolism Sterol biosynthesis Sterol metabolism Stress response Transmembrane Transmembrane helix | MASTQVVFIV | MASTQVVFIVTLFLYLLITRWRRKNEKSFIASEEPKQPEWRDYTPAELKEYNGSKNSLVFLAIKGTVYNVTMGSKFYGPQGPYSAFAGHDASRGLAKNSFDDEFIPDSDAEELDDCSDLNDEERQALNDWKAFFDQKYQAVGRLISPREARAAATISETEEKVAHN | ergosterol biosynthetic process endomembrane system; endoplasmic reticulum; endoplasmic reticulum membrane; membrane enzyme activator activity metal ion binding steroid binding Schizosaccharomyces pombe Endoplasmic reticulum Heme Iron Lipid biosynthesis Lipid metabolism Membrane Metal-binding Phosphoprotein Reference ... |
DNA repair DNA strand elongation involved in DNA replication DNA-templated DNA replication mitotic DNA replication leading strand elongation UV-damage excision repair | chromatin; Ctf18 RFC-like complex; cytosol; DNA replication factor C complex; Elg1 RFC-like complex; nucleus; Rad17 RFC-like complex | ATP binding ATP hydrolysis activity DNA binding DNA clamp unloader activity | Schizosaccharomyces pombe | ATP-binding Direct protein sequencing DNA damage DNA replication Nucleotide-binding Nucleus Reference proteome | MSIEKGKGRA | MSIEKGKGRAMDIDLPLGSESTLPWVEKYRPANLEDVVSHKDIISTLEKFISSNRVPHMLFYGPPGTGKTSTILACARKIYGPNYRNQLMELNASDDRGIDAVREQIKNFASTRQIFASTFKMIILDEADAMTLAAQNALRRVIEKYTKNVRFCIICNYINKISPAIQSRCTRFRFQPLPPKEIEKTVDHVIQSEHCNIDPDAKMAVLRLSKGDMRKALNILQACHAAYDHIDVSAIYNCVGHPHPSDIDYFLKSIMNDEFVIAFNTISSIKQQKGLALQDILTCIFEALDELEIKPNAKIFILDQLATIEHRMSFGCSE... | DNA repair DNA strand elongation involved in DNA replication DNA-templated DNA replication mitotic DNA replication leading strand elongation UV-damage excision repair chromatin; Ctf18 RFC-like complex; cytosol; DNA replication factor C complex; Elg1 RFC-like complex; nucleus; Rad17 RFC-like complex ATP binding ATP hydr... |
actin cytoskeleton organization ascospore formation ascospore-type prospore membrane formation spindle pole body organization | cell cortex; cell cortex of cell tip; central plaque of spindle pole body; cortical cytoskeleton; cytoplasm; cytosol; mating projection actin fusion focus; mating projection tip; medial cortex; myosin I complex; prospore membrane | calcium ion binding enzyme regulator activity | Schizosaccharomyces pombe | Cytoplasm Meiosis Membrane Reference proteome Repeat Sporulation | MPASKEQTDE | MPASKEQTDEMKEAFVLYDIDKDGLIPTSHVGSVLRSLGINVTDAELAKLSNELGDAIDEKKFMSFVSNKLRETESEEEYIKAFRVFDKDNSGYIETAKFADYMKTLGEKLSDNEVQLMVQEADPTNSGSFDYYDFVQRIMAK | actin cytoskeleton organization ascospore formation ascospore-type prospore membrane formation spindle pole body organization cell cortex; cell cortex of cell tip; central plaque of spindle pole body; cortical cytoskeleton; cytoplasm; cytosol; mating projection actin fusion focus; mating projection tip; medial cortex; ... |
DNA repair mRNA splicing, via spliceosome protein K63-linked ubiquitination | cytoplasm; cytosol; nuclear envelope; nucleus; post-mRNA release spliceosomal complex; Prp19 complex; spliceosomal complex; U2-type catalytic step 1 spliceosome | ubiquitin protein ligase activity ubiquitin-protein transferase activity | Schizosaccharomyces pombe | 3D-structure Direct protein sequencing DNA damage DNA repair mRNA processing mRNA splicing Nucleus Reference proteome Repeat Spliceosome Transferase Ubl conjugation pathway WD repeat | MFCSISGETP | MFCSISGETPKEPVISRVSGNVYEKRLIEQVIRETSKDPVTQQECTLEDLVPVKVPDFVRPRPPSATSLPALLSLFQEEWDSVALEQFELRRNLTETKQELSTALYSLDAALRVISRLTKERDEAREALAKFSDNIGTVSSKTIEVQEVEMGESDDQLKTSLRSTVEKTFQELSSKRKRTKLQPKWATDDAVSQLLQATPSTILENLETESTTSFFPSPENSSFVLCLHKDELLCLDIQSNSTLKIFEGSALACCWLTSSKIAVATADAISIFEFPVSSSGLQSVGEPTSSIPIDEKVNFLQAHPSGEYLLAASNEKCYI... | DNA repair mRNA splicing, via spliceosome protein K63-linked ubiquitination cytoplasm; cytosol; nuclear envelope; nucleus; post-mRNA release spliceosomal complex; Prp19 complex; spliceosomal complex; U2-type catalytic step 1 spliceosome ubiquitin protein ligase activity ubiquitin-protein transferase activity Schizosacc... |
intracellular monoatomic cation homeostasis intracellular potassium ion homeostasis intracellular signal transduction phosphorylation | cytosol | ATP binding protein serine kinase activity protein serine/threonine kinase activity | Schizosaccharomyces pombe | ATP-binding Cytoplasm Kinase Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MGEKDKLHEI | MGEKDKLHEISSKFASLGLGSLKSTPKARETTEPPPPSSQQPPSTPNGKEAASPSALKQNVRPSLNSVQQTPASIDAVASSSNVSLQSQQPLSKPVVSSKPNQTTAMPPPSNNPSRHVSSTSNKPAAVSPNPAAHHAELPSGSVPPSASVSRANSTATTTPHKAGVVSNPAAANVHVLSVAASPNPSTPSNGPAPVSTTATPSRNPVTRLQRIFSQNSVSRQNSRTGRGAAVANTEETNSTGGSETGGAANSSSTSNPSSAKWSRFTVYDDASHTHQLRPARRQEKLGKMLKDFLAGNSKKREEERIAKEAADAQHQLSL... | intracellular monoatomic cation homeostasis intracellular potassium ion homeostasis intracellular signal transduction phosphorylation cytosol ATP binding protein serine kinase activity protein serine/threonine kinase activity Schizosaccharomyces pombe ATP-binding Cytoplasm Kinase Nucleotide-binding Phosphoprotein Refe... |
chromatin remodeling regulation of DNA-templated transcription transcription initiation-coupled chromatin remodeling | Clr6 histone deacetylase complex I''; cytoplasm; cytosol; nucleus; Rpd3L complex; Rpd3L-Expanded complex; Rpd3S complex | H3-H4 histone complex chaperone activity histone binding | Schizosaccharomyces pombe | 3D-structure Chromatin regulator Direct protein sequencing Nucleus Reference proteome Repeat Transcription Transcription regulation WD repeat | MAVSAVPHPS | MAVSAVPHPSKQAQASEEGINQEKCINEEYKIWKKNSPFLYDLIITRALEWPCMSLQWYPEQQIFAEHGYTEQKMFLGVRADVGKYLLAVASIQLPYLNQTVPPTTMEGASAGDESSLRVNISNLYSHPESVCSAKLMPQDDSCVATVGNYHNDVLVFDKESFESYSSASESPLKPKYRLTKHTQPCTSVCWNFLSKGTLVSGSQDATLSCWDLNAYNESDSASVLKVHISSHEKQVSDVRFHYKHQDLLASVSYDQYLHVHDIRRPDASTKPARSVHAHSGPIHSVAFNPHNDFILATCSTDKTIALWDLRNLNQRLHT... | chromatin remodeling regulation of DNA-templated transcription transcription initiation-coupled chromatin remodeling Clr6 histone deacetylase complex I''; cytoplasm; cytosol; nucleus; Rpd3L complex; Rpd3L-Expanded complex; Rpd3S complex H3-H4 histone complex chaperone activity histone binding Schizosaccharomyces pombe ... |
regulation of cytoplasmic translational fidelity tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation | cytoplasm; cytosol; elongator holoenzyme complex; nucleus | 4 iron, 4 sulfur cluster binding metal ion binding tRNA binding tRNA uridine(34) acetyltransferase activity | Schizosaccharomyces pombe | 4Fe-4S Acyltransferase Cytoplasm Iron Iron-sulfur Metal-binding Reference proteome RNA-binding S-adenosyl-L-methionine Transferase tRNA processing tRNA-binding | MSTSSLAFLK | MSTSSLAFLKAKACAEIVAELIASENQNKVINLNALKMRISKKHQLSESPRLTDIIAAIPPDAYLKESLMRKLRAKPVRTASGIAVVAVMCKPHRCPHIAMTGNVCVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPYEQARGRVEQLRSLGHTVDKVEYIIMGGTFMSLPESYRHTFIANLHNALSGATTEDLDEAVKFSEQSETKCVGITIETRPDYCLDQHLDEMLRYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCETFQLAKDTGYKVVTHMMPDLPNVGMERDIFQFQEYFENPAFRTDGLKLYPTLVI... | regulation of cytoplasmic translational fidelity tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation cytoplasm; cytosol; elongator holoenzyme complex; nucleus 4 iron, 4 sulfur cluster binding metal ion binding tRNA binding tRNA uridine(34) acetyltransferase activity Schizosaccharomyces pombe 4Fe-4S Acyltransf... |
glutathione import across plasma membrane glutathione transmembrane transport protein transport | endoplasmic reticulum membrane; plasma membrane; plasma membrane of cell tip | glutathione transmembrane transporter activity oligopeptide transmembrane transporter activity | Schizosaccharomyces pombe | Cell membrane Coiled coil Endoplasmic reticulum Glycoprotein Membrane Peptide transport Phosphoprotein Protein transport Reference proteome Transmembrane Transmembrane helix Transport | MTARNSASIP | MTARNSASIPTSIRKTSENEVSGDETPAGVGNLSTKTASKTSLTFRQSSSDESTSSYSGNHHNINIQHHPNRPFRTNSSSFSPNDYSISESPSKSKKDGVHVSAVQLDNETDSEVESEVEELERELEAIEDSVYPEVRAAVNPTDDVNLPVNTWRTWVLTTIFVIVFAAVNQFFSLRYPALSISFIVAQLILFPLGKLLNLLPNWKIGYGRFSFYLNSSPFNVKEHAAITIAVSLTSSTAYATNILSAQTSFYKQNLSWGYKILIVLTSQMLGYGFAGLTRRWIVYPAAMIWPQTLVSTVLFRTLHGNSGNDIGVLKNNR... | glutathione import across plasma membrane glutathione transmembrane transport protein transport endoplasmic reticulum membrane; plasma membrane; plasma membrane of cell tip glutathione transmembrane transporter activity oligopeptide transmembrane transporter activity Schizosaccharomyces pombe Cell membrane Coiled coil... |
mRNA 5'-splice site recognition spliceosomal snRNP assembly | catalytic step 2 spliceosome; cytosol; nucleus; pICln-Sm protein complex; post-mRNA release spliceosomal complex; precatalytic spliceosome; Prp19 complex; spliceosomal complex; U1 snRNP; U2 snRNP; U2-type prespliceosome; U4/U6 x U5 tri-snRNP complex; U5 snRNP | RNA binding | Schizosaccharomyces pombe | 3D-structure Cytoplasm mRNA processing mRNA splicing Nucleus Reference proteome Ribonucleoprotein | MADLVDKPRS | MADLVDKPRSELSEIELARLEEYEFSAGPLSVLQQAVKNHDQVLINCRNNKKLLARVKAFDRHSNMVLENVKEMWTEKKRTASGKKGKAINKDRFISKMFLRGDGVVLVVRIPSA | mRNA 5'-splice site recognition spliceosomal snRNP assembly catalytic step 2 spliceosome; cytosol; nucleus; pICln-Sm protein complex; post-mRNA release spliceosomal complex; precatalytic spliceosome; Prp19 complex; spliceosomal complex; U1 snRNP; U2 snRNP; U2-type prespliceosome; U4/U6 x U5 tri-snRNP complex; U5 snRNP ... |
mRNA catabolic process nuclear-transcribed mRNA catabolic process, exonucleolytic nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' polyuridylation-dependent mRNA catabolic process | cytoplasm; cytosol; P-body | 3'-5'-RNA exonuclease activity metal ion binding poly(U) RNA binding | Schizosaccharomyces pombe | 3D-structure Cytoplasm Exonuclease Hydrolase Magnesium Manganese Metal-binding Nuclease Reference proteome RNA-binding | MDLKPNIRRK | MDLKPNIRRKEKRNLLKGEAALEKKGSIDRKTKNKAYPSTTHDPHQNDDSNIPGLGSGLLERIKDIVQRPTDTQLKGQDSNHKKASLTETKTEKAKVKPKAKKKNSKEKISKSSKQDEHKTDVHKESVSKLSKNLESRNNRDENSAKREKNNSHQVEADTNNATEMVSSNAKKSVYPLYYDSATVKKGLKSGTLFKGTLRILENHRSAFACMEDIPDFYVDGPIARNRAFHNDVVIVEPVMNNDSPTEKSNFLQNGVEKVKIKDHDDELGGAMEHLERLEIKSVASFKGDSRTRARVVAIEKRAEISKIVGILRAPGWSL... | mRNA catabolic process nuclear-transcribed mRNA catabolic process, exonucleolytic nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' polyuridylation-dependent mRNA catabolic process cytoplasm; cytosol; P-body 3'-5'-RNA exonuclease activity metal ion binding poly(U) RNA binding Schizosaccharomyces pombe ... |
calcium ion transmembrane transport cell volume homeostasis intracellular calcium ion homeostasis | cortical endoplasmic reticulum; endoplasmic reticulum membrane; membrane | calcium channel activity calcium ion binding mechanosensitive monoatomic ion channel activity | Schizosaccharomyces pombe | Endoplasmic reticulum Membrane Reference proteome Stress response Transmembrane Transmembrane helix | MNEHRREPHR | MNEHRREPHRRSGYQDDSAFTNTEKLVDELDHNVEPEQLLEKNRTDFKLMYVIVKFYRWFNNLSFITRWITIWFPLAGALVIPLAVGVSPYPNAKLGGVRIFWIFVWLEVAWGGFWVSRVIARLLPYILYPLMGILPFTMYKYTVILTALEMPLAIFFCSIVCVCTFSPIMIGKGNFTSTTVTTTTSATATPTASASSNAVESVFVTKTAASVPSWIKVITKILGAAVVTSIVLLLEKIFLHFIGFHYHEVQYQYRITDNKRNTAVLAKLLTAALDAPYHDSPRVRRQDYLLGLIDTRSMSESKGSGNGKLRKVKKISKN... | calcium ion transmembrane transport cell volume homeostasis intracellular calcium ion homeostasis cortical endoplasmic reticulum; endoplasmic reticulum membrane; membrane calcium channel activity calcium ion binding mechanosensitive monoatomic ion channel activity Schizosaccharomyces pombe Endoplasmic reticulum Membra... |
NLS-bearing protein import into nucleus protein import into nucleus | cytoplasm; nuclear envelope; nuclear periphery; nucleoplasm; nucleus | GTP binding nuclear import signal receptor activity nuclear localization sequence binding | Schizosaccharomyces pombe | Nucleus Protein transport Reference proteome Repeat Transport | MSASSRFIPE | MSASSRFIPEHRRQNYKGKGTFQADELRRRRETQQIEIRKQKREENLNKRRNLVDVQEPAEETIPLEQDKENDLELELQLPDLLKALYSDDIEAQIQATAKFRKALSKETNPPIQKVIDAGVVPRFVEFLSHENNLLKFEASWALTNVASGSSNQTHVVVEANAVPVFVSLLSSSEQDVREQAVWALGNIAGDSPMCRDHVLQCGVLEPLLNIIESNRRLSMLRNSTWTLSNMCRGKNPQPDWNSISQVIPVLSKLIYTLDEDVLVDALWAISYLSDGANEKIQAIIDAGIPRRLVELLMHPSAQVQTPALRSVGNIVTG... | NLS-bearing protein import into nucleus protein import into nucleus cytoplasm; nuclear envelope; nuclear periphery; nucleoplasm; nucleus GTP binding nuclear import signal receptor activity nuclear localization sequence binding Schizosaccharomyces pombe Nucleus Protein transport Reference proteome Repeat Transport MSAS... |
cell division mitotic sister chromatid biorientation mitotic sister chromatid segregation regulation of cell cycle regulation of mitotic cytokinesis signaling | chromatin; chromosome passenger complex; cytoplasm; kinetochore; meiotic spindle midzone; mitotic spindle; mitotic spindle midzone; nucleus; pericentric heterochromatin | metal ion binding | Schizosaccharomyces pombe | Cell cycle Cell division Centromere Chromosome Cytoplasm Cytoskeleton Metal-binding Mitosis Nucleus Phosphoprotein Reference proteome Repeat Zinc | MKPITSSSKR | MKPITSSSKRRWNRFRREMCNYSKRLDTFQKKKWPRAKPTPETLATVGFYYNPISESNSEERLDNVTCYMCTKSFYDWEDDDDPLKEHITHSPSCPWAYILSSKNNPNQNPQAAALTKCREQTFVDKVWPYTNRPDYHCEPSVMAASGFVYNPTADAKDAAHCLYCDINLHDWEPDDDPYTEHKRRRADCVFFTWKDPNSLSPTKLSFLSTSNIDPEDLTEDNSILPVSPTRDSTKSHKTLNFSPSRKNNLNARPLTMSLYTNTSEEKDSQPTRAPQSPTKPVLLTAPRRKNKSPKKSKPAVFKPVKPIFSDEDEDDDDL... | cell division mitotic sister chromatid biorientation mitotic sister chromatid segregation regulation of cell cycle regulation of mitotic cytokinesis signaling chromatin; chromosome passenger complex; cytoplasm; kinetochore; meiotic spindle midzone; mitotic spindle; mitotic spindle midzone; nucleus; pericentric heteroch... |
mRNA transport protein import into nucleus | cytoplasm; cytosol; mitotic spindle midzone; nuclear envelope; nuclear periphery; nucleus | GTP binding nuclear import signal receptor activity nuclear localization sequence binding | Schizosaccharomyces pombe | Cytoplasm mRNA transport Nucleus Protein transport Reference proteome Repeat Transport | MGDNPWVLQE | MGDNPWVLQEQVLVELSEVIKNSLSENSQTRNAALNLLEKAKDIPDLNNYLTCILINATELSVSIRSAAGLLLKNNVRVSSLESGSGLQSLDYTKSTVIRGLCDPEQLIRGISGNVITTIISRWGISTWPEVLPQLMEMLSSPASTTQEGAFSALTKICEDSAQELDRDFNGTRPLDFMIPRFIELARHENPKIRTDALFCLNQFVLIQSQSLYAHIDTFLETCYALATDVSPNVRKNVCQALVYLLDVRPDKIAPSLGSIVEYMLYSTQDSDQNVALEACEFWLAIAEQPDLCSALGPYLDKIVPMLLQGMVYSDMDLL... | mRNA transport protein import into nucleus cytoplasm; cytosol; mitotic spindle midzone; nuclear envelope; nuclear periphery; nucleus GTP binding nuclear import signal receptor activity nuclear localization sequence binding Schizosaccharomyces pombe Cytoplasm mRNA transport Nucleus Protein transport Reference proteome ... |
heme biosynthetic process protoporphyrinogen IX biosynthetic process | mitochondrial matrix; mitochondrion | 5-aminolevulinate synthase activity pyridoxal phosphate binding transaminase activity | Schizosaccharomyces pombe | Acyltransferase Heme biosynthesis Mitochondrion Pyridoxal phosphate Reference proteome Transferase Transit peptide | MERVVKLAAK | MERVVKLAAKHCPFVSKADPSALRRMAGAGLIRAGARCPVVRHALPVAAATGADVSRGFKSDSKQMAMEPSLDEIHLKAGVVNTGSRTCRHADAVKAAAEAATTTPVTKKHQMPKHYASDLNGVGPATTPRFDYDTFYREELDKKHRDKSYRYFNNINRLAKEYPLAHLADPNTRVEVWCSNDYLNMGGHKKIREAMHQCIETYGGGAGGTRNIAGHNQHAVRLEKSLADLHQKPAALVFGSCYVANDATLSTLGRKLPNCIFLSDEMNHASMINGIRNSRCEKIIFKHNDLVDLEAKLASLPLNRPKIIAFESVYSMSG... | heme biosynthetic process protoporphyrinogen IX biosynthetic process mitochondrial matrix; mitochondrion 5-aminolevulinate synthase activity pyridoxal phosphate binding transaminase activity Schizosaccharomyces pombe Acyltransferase Heme biosynthesis Mitochondrion Pyridoxal phosphate Reference proteome Transferase Tra... |
mRNA processing phosphorylation positive regulation of transcription by RNA polymerase II positive regulation of transcription elongation by RNA polymerase II | chromatin; CTDK-1 complex; cyclin/CDK positive transcription elongation factor complex; nuclear cyclin-dependent protein kinase holoenzyme complex; nucleolus; nucleus | ATP binding cyclin binding cyclin-dependent protein serine/threonine kinase activity RNA polymerase II CTD heptapeptide repeat kinase activity RNA polymerase II CTD heptapeptide repeat S2 kinase activity | Schizosaccharomyces pombe | ATP-binding Kinase mRNA processing Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transcription Transferase | MSYSKSTIYR | MSYSKSTIYRRQGTEPNSHFRRTVEEKSQLSGTNEESLGGHTLSSNAFKNNSSSISPSSSAKDPREQRKRTFPLNDTHSSRARQHERPFRSRKSRRRKGKKAFSPRPGSPPSPSFYRSGSQKRARNLTTKDYFAKRSESSSSASVSPISPSANRNDSKRQASSFRRSPPSSVHMKPSAFNGRKVSRRPSSSPPPIPSIPHETTSSDTQKKSSVSSGFPENKHGKFHFHIPNERRSRFDQPPSKRMALTSTARESVPAPLPSPPSGPIYTYTYPKPAYEKIDQIGEGTYGKVYKAINTVTGDLVALKRIRLEQEKDGFPIT... | mRNA processing phosphorylation positive regulation of transcription by RNA polymerase II positive regulation of transcription elongation by RNA polymerase II chromatin; CTDK-1 complex; cyclin/CDK positive transcription elongation factor complex; nuclear cyclin-dependent protein kinase holoenzyme complex; nucleolus; nu... |
phosphatidylcholine biosynthetic process phosphatidylethanolamine biosynthetic process protein autoprocessing | cell division site; cytosol; endosome membrane; fungal-type vacuole membrane; Golgi membrane; Golgi stack | metal ion binding phosphatidylserine decarboxylase activity phospholipid binding | Schizosaccharomyces pombe | Calcium Cytoplasm Decarboxylase Endosome Golgi apparatus Lipid biosynthesis Lipid metabolism Lyase Membrane Metal-binding Phospholipid biosynthesis Phospholipid metabolism Pyruvate Reference proteome Zymogen | MPFTKSCRSA | MPFTKSCRSANTLRKGIKNGKLILKIIVNDIDNVESCLSGDESNDSKKSSASFYMKLKYGSYRALADNILSTDENRKEDIAVFDVPLPNGLQIDTFTLCLYRKSKWKKQIVGEAYIGIQALLLSTNPDETCKYPVISPPSGRNKENQSPSHQICNLSLKWIIYDPEDADADSKTLAKAWLQQIKMNQTSIDPMSNISKSLKELEVDNVESDLEDSSFIAEPDSSIPPSESSVSISTDTGKETPPSKSKKSSNQPYVSIGEGNSDLLGFVFLEIISVSNLPPLKNVFRTGFDMDPFVITAFSKNIFRTKWLRHNLNPVYNE... | phosphatidylcholine biosynthetic process phosphatidylethanolamine biosynthetic process protein autoprocessing cell division site; cytosol; endosome membrane; fungal-type vacuole membrane; Golgi membrane; Golgi stack metal ion binding phosphatidylserine decarboxylase activity phospholipid binding Schizosaccharomyces pom... |
DNA damage response nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts pericentric heterochromatin formation protein localization protein ubiquitination regulatory ncRNA-mediated heterochromatin formation silent mating-type cassette heterochromatin formation subtelomeric heterochromatin formation ... | chromosome, telomeric region; CLRC complex; Cul4-RING E3 ubiquitin ligase complex; cytosol; nucleus; pericentric heterochromatin | ubiquitin protein ligase binding | Schizosaccharomyces pombe | Chromatin regulator Chromosome Cytoplasm Direct protein sequencing Isopeptide bond Nucleus Reference proteome Transcription Transcription regulation Ubl conjugation | MPPEAKRIVV | MPPEAKRIVVKGFDPRKSRQRQETYYVTMIDRLNMALQVVMAGLGLKTGYQELYSGVENLTRADQASRCFNILQHHMSSGIQLLKDSAESFIQLEGTETDTNACTVVVGCWNKWLERVEIVQNIFYYMDKTFLSHHPDYPTIEELSLSLFREKLMAVKNIQIPFLNSLLQSFENLHSSKSTDHAYLQDAMLMLHRTEMYSSVFVPMYLVMLSRFYDTESSQKIQELPLEEYLEYAMSSLEREDAYVEKFDIVRDKKSIRETVQRCLITSHLDTLTKGISQFIEKRDAHSCKLLYALLQFNHETEYLIQPWSDCLVDVGFK... | DNA damage response nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts pericentric heterochromatin formation protein localization protein ubiquitination regulatory ncRNA-mediated heterochromatin formation silent mating-type cassette heterochromatin formation subtelomeric heterochromatin formation ... |
DNA damage response DNA strand invasion double-strand break repair via homologous recombination meiotic DNA recombinase assembly meiotic joint molecule formation reciprocal meiotic recombination | cytosol; nucleus; Rad51B-Rad51C-Rad51D-XRCC2 complex; Rad51C-XRCC3 complex; replication fork; site of double-strand break | ATP binding ATP hydrolysis activity ATP-dependent DNA damage sensor activity DNA binding | Schizosaccharomyces pombe | ATP-binding DNA damage DNA repair Nucleotide-binding Nucleus Reference proteome | MLSSQHRLVT | MLSSQHRLVTQPAIRAYEAFSAPGFGFNSKLLDDAFGGSGLKRGYISEVCGAPGMGKTSLALQITANALLSGSRVIWVETCQPIPMERLRQLLDNHVPSSQDEEEKCDTDELLNLLDVVYAPNLVNILAFLRNFDQEKHLKEIGLLIIDNLSMPIQLAYPTSPEDYAYLRLRRNTSKKSSLSDSSQKENTLTLNKENEFSSKDDSNFAFHNSSTKTTINRRKKAIGTISSLLSKITSSCYVAIFVTTQMTSKVVSGIGAKLIPLLSTNWLDNLSYRLILYSRHSTEESKDGQSRPSHQLLRYAFMAKQPPAHSAESELAF... | DNA damage response DNA strand invasion double-strand break repair via homologous recombination meiotic DNA recombinase assembly meiotic joint molecule formation reciprocal meiotic recombination cytosol; nucleus; Rad51B-Rad51C-Rad51D-XRCC2 complex; Rad51C-XRCC3 complex; replication fork; site of double-strand break ATP... |
ascospore formation intracellular signal transduction phosphorylation regulation of meiotic nuclear division signaling | cell division site; cytoplasm; cytosol; nucleus | ATP binding protein serine kinase activity protein serine/threonine kinase activity | Schizosaccharomyces pombe | ATP-binding Kinase Meiosis Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Sporulation Transferase | MKKYLWGTPT | MKKYLWGTPTTNTVFTGKQPKYTKEVRKCISIDEVYNVVRKVGDGTFGSVYLATTKTPSKEVVAIKSMKKKLAKVSDATRLREVHSLLRLSENENIVNIFDLYIDQFRCLHIVMEFLDCNLYQLISTRKNDPLTLEQVQDIMRQIFKGLNHIHTNGFFHRDMKPENILISSNSDSSSFNVKIADFGLAREINSRPPYTEYVSTRWYRAPELLLRDSYYSFPVDIYAAGCMAFEIATLQPIFPGNDDFDQLYKMCEILGSPDEQSQNTGDKGGGIWDRAELLANKLGISLPKMAPLDFGDLFSPPWNLAFASMLSQLLKWD... | ascospore formation intracellular signal transduction phosphorylation regulation of meiotic nuclear division signaling cell division site; cytoplasm; cytosol; nucleus ATP binding protein serine kinase activity protein serine/threonine kinase activity Schizosaccharomyces pombe ATP-binding Kinase Meiosis Nucleotide-bind... |
double-strand break repair via homologous recombination mRNA export from nucleus proteasome assembly | cytoplasm; cytosol; nucleus; proteasome complex; proteasome regulatory particle, lid subcomplex | ion binding molecular adaptor activity | Schizosaccharomyces pombe | Cytoplasm mRNA transport Nucleus Reference proteome Transport | MSRAALPSLE | MSRAALPSLENLEDDDEFEDFATENWPMKDTELDTGDDTLWENNWDDEDIGDDDFSVQLQAELKKKGVAAN | double-strand break repair via homologous recombination mRNA export from nucleus proteasome assembly cytoplasm; cytosol; nucleus; proteasome complex; proteasome regulatory particle, lid subcomplex ion binding molecular adaptor activity Schizosaccharomyces pombe Cytoplasm mRNA transport Nucleus Reference proteome Trans... |
cellular response to oxidative stress positive regulation of autophagosome maturation positive regulation of vacuole fusion, non-autophagic regulation of aerobic respiration signaling | cytoplasm; fungal-type vacuole membrane; mitochondrial matrix | MAP kinase phosphatase activity metal ion binding myosin phosphatase activity protein serine/threonine phosphatase activity | Schizosaccharomyces pombe | Hydrolase Magnesium Manganese Membrane Metal-binding Protein phosphatase Reference proteome Vacuole | MSIRFLKRLR | MSIRFLKRLRAPLYIQNAYCSKNYFYRSFIQYYSPSNGPYLKISMNKAPQSLGLCTARGDSPTNQDRMAYGYLNNLKDTTNRDSPFFYGLFDGHGGTECSEFLSTNLGKIIENQDLNDTEKILKEVHSVGGYMAGLKPPFSLRTVLQSRDEDLLWRARLYYSFLQADMDYLTNYARPSPDSAVPGAVGTVAIITSKNNLSYWESDSYIIHLAHVGDTRALLCDSRTGRAHRLTFQHHPADVEEARRLRRYNMGFSRDSFGQKRFAWVANTRSFGDGYKLKKLGVVAEPQLTSIHSLRDDWSFLTLLSDGITDVVSDDEVV... | cellular response to oxidative stress positive regulation of autophagosome maturation positive regulation of vacuole fusion, non-autophagic regulation of aerobic respiration signaling cytoplasm; fungal-type vacuole membrane; mitochondrial matrix MAP kinase phosphatase activity metal ion binding myosin phosphatase activ... |
formation of cytoplasmic translation initiation complex translational initiation | cytosol; eukaryotic 43S preinitiation complex; eukaryotic 48S preinitiation complex; eukaryotic translation initiation factor 3 complex; eukaryotic translation initiation factor 3 complex, eIF3e; eukaryotic translation initiation factor 3 complex, eIF3m | RNA binding translation initiation factor activity translation initiation factor binding | Schizosaccharomyces pombe | Cytoplasm Initiation factor Phosphoprotein Protein biosynthesis Reference proteome | MSRFFKGGSS | MSRFFKGGSSDSDAESVDSSEENRLTSSRLKKQDDSSSEEESSEEESASSSESESSEEESESEESEVEVPKKKAVAASEDSESDSESSEEEEETESEEDSEVSDESESESESESESEEESESEEESDESERSGPSSFLKKPEKEEAKPAGLKFLRGESSEESSDEEEGRRVVKSAKDKRYEEFISCMETIKNAMSSNNWIVVSNEFDHLNKVSQKCKEAGRNPPPYIEFLSALDQKLESADKAFIKSLDAANGRAFNALKQRVRKNNRQFQSDIDRYRKDPEGFMKPAELNEIPKPAGKAGQDEVIVDGVATRGIVAPTE... | formation of cytoplasmic translation initiation complex translational initiation cytosol; eukaryotic 43S preinitiation complex; eukaryotic 48S preinitiation complex; eukaryotic translation initiation factor 3 complex; eukaryotic translation initiation factor 3 complex, eIF3e; eukaryotic translation initiation factor 3 ... |
negative regulation of mitotic DNA replication initiation protein polyubiquitination SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | cytoplasm; nuclear SCF ubiquitin ligase complex; SCF ubiquitin ligase complex | protein-macromolecule adaptor activity ubiquitin ligase-substrate adaptor activity | Schizosaccharomyces pombe | Cytoplasm Nucleus Reference proteome Repeat Ubl conjugation pathway WD repeat | MSLSRCPTDN | MSLSRCPTDNSSSRINSSVPLINSSSPATPPESFDPQVFPSSLIHGDNLLPQDDQIASDPRSESNSCNGNTSSSLPCTDSYQYPLKHSCTPSFLRKFNESIENVSYKCLDHSPPDSVPGDFSISLVPQRNFLYSHSSLPPKIISIDRNNRIKLDNSISSNSDNFPPSPKVDTSNTVSPGSKPISEDLEDLNLQSIVQTFEDLPEGIQSYAFFQLLRSCNRQSMRLLLNECEPLLKKDILSNLPFSIVQSILLNLDIHSFLSCRLVSPTWNRILDVHTSYWKHMFSLFGFQINENDWKYANPNLNRPPFLHNDQISDDYFP... | negative regulation of mitotic DNA replication initiation protein polyubiquitination SCF-dependent proteasomal ubiquitin-dependent protein catabolic process cytoplasm; nuclear SCF ubiquitin ligase complex; SCF ubiquitin ligase complex protein-macromolecule adaptor activity ubiquitin ligase-substrate adaptor activity Sc... |
regulation of transcription by RNA polymerase II septin ring organization transcription initiation-coupled chromatin remodeling | cytoplasm; cytosol; medial cortex septin ring; nucleus; SAGA complex | transcription coactivator activity | Schizosaccharomyces pombe | Cytoplasm Nucleus Reference proteome Transcription Transcription regulation | MERNNGLGDY | MERNNGLGDYTYRYHGKELSLDDFQNKQGIESSDDAFLSKIYENVSNFNVPRKLHDIEHKFSKEEPSLILHIHKFHFRFEQQDGAFTYNGPVKSILQYIRMELIPPDCLEVFRNSDVKFYDGCLTVRIIDHRQSPSADQTVQPQPGSTNQQQQNNTNPINNQPEDTKPNTNSPPVYHTVLRPTPETLWQDLCLLSESFANSLSDEAVLTLESNILLASEAPLFLTPAKSKAEMIQFMNQLADSAPPCTRKKPQGSAQLADEEAERLEKENLLLLMDDQRKRDFQPTFQRLQFIENVRRKRAILQQRQMQMQQQQKAQQQQ... | regulation of transcription by RNA polymerase II septin ring organization transcription initiation-coupled chromatin remodeling cytoplasm; cytosol; medial cortex septin ring; nucleus; SAGA complex transcription coactivator activity Schizosaccharomyces pombe Cytoplasm Nucleus Reference proteome Transcription Transcript... |
cellular detoxification glutathione catabolic process proteolysis | fungal-type vacuole; plasma membrane; vacuolar membrane | glutathione hydrolase activity leukotriene C4 gamma-glutamyl transferase activity | Schizosaccharomyces pombe | Acyltransferase Glycoprotein Hydrolase Membrane Protease Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix Vacuole | MSPTDTTPLL | MSPTDTTPLLYSWDDQSRHQDPDWHKLRNYHGAWYRRISRRRFSQFIFAFGLMTLFVLVYSISSNLHTPTQFTGHKVRGRRGAVASEVPVCSDIGVSMLADGGNAVDAAIASTFCIGVVNFFSSGIGGGGFMLIKHPNETAQSLTFREIAPGNVSKHMFDKNPMLAQVGPLSIAIPGELAGLYEAWKSHGLLDWSKLLEPNVKLAREGFPVTRAMERVLKLPEMAHLLKDPIWQPILMPNGKVLRAGDKMFRPAYAKTLEIIANKGIEPFYRGELTNSMVKFIQDNGGIVTVEDFGNYSTVFADALHTSYRGHDVYTCTL... | cellular detoxification glutathione catabolic process proteolysis fungal-type vacuole; plasma membrane; vacuolar membrane glutathione hydrolase activity leukotriene C4 gamma-glutamyl transferase activity Schizosaccharomyces pombe Acyltransferase Glycoprotein Hydrolase Membrane Protease Reference proteome Signal-anchor... |
meiotic cell cycle nucleophagy reticulophagy | cytoplasm; endoplasmic reticulum; phagophore assembly site | endoplasmic reticulum-autophagosome adaptor activity nucleic acid binding zinc ion binding | Schizosaccharomyces pombe | Endoplasmic reticulum Meiosis Metal-binding Phosphoprotein Reference proteome Zinc Zinc-finger | MNNPFKDMDC | MNNPFKDMDCYEILQVNHDSDLQEIKANYRKLALQYHPDRNPGIEDYNEIFSQINAAYNILSNDDKRKWHEKDYLRNQYSVQIEDVLQHLQTIEKIPFESTSAFVERLRQDEKIAGSTDDLPTLGDTTWLWTYAKPIYQKWLRFSTKKSFEWEALYNEEEESDAATRRLMKRQNQRQIQYCIQRYNELVRDLIGKACDLDPRRKNVVKLSDGERYNSLQEASRKQSERDRRQYQETFKNQSIASWTIIDQEETSSDDESLSKEIVNSNPIMCMVCNKNFRSQNQLENHENSKKHKKNLRKMNQEIKKHAKEAQKNAESNK... | meiotic cell cycle nucleophagy reticulophagy cytoplasm; endoplasmic reticulum; phagophore assembly site endoplasmic reticulum-autophagosome adaptor activity nucleic acid binding zinc ion binding Schizosaccharomyces pombe Endoplasmic reticulum Meiosis Metal-binding Phosphoprotein Reference proteome Zinc Zinc-finger MNN... |
tRNA N1-guanine methylation | cytoplasm; nucleolus; nucleus | tRNA (guanosine(9)-N1)-methyltransferase activity tRNA binding | Schizosaccharomyces pombe | 3D-structure Cytoplasm Methyltransferase Nucleus Phosphoprotein Reference proteome S-adenosyl-L-methionine Transferase tRNA processing | MENKDALDIG | MENKDALDIGKDDTNTSEADVSKNETQEQPVLSKSALKRLKRQQEWDAGREKRAEMRREKKRLRKEERKRKIEAGEVVKSQKKRIRLGKVVPSSIRIVLDCAFDDLMNDKEINSLCQQVTRCHSANRTALHPVELFATNFGGRLKTRQDFVLKGQQNNWKRYNPTTKSYLEEFESQKEKLVYLSADSDNTITELDEDKIYIIGAIVDKNRYKNLCQNKASEQGIKTAKLPIDEYIKITDRKILTVNQVFEILSLWLEYRDWEKAFMEVIPKRKGILLKSDESFDVSEDTRSQSNQSDSELEKEN | tRNA N1-guanine methylation cytoplasm; nucleolus; nucleus tRNA (guanosine(9)-N1)-methyltransferase activity tRNA binding Schizosaccharomyces pombe 3D-structure Cytoplasm Methyltransferase Nucleus Phosphoprotein Reference proteome S-adenosyl-L-methionine Transferase tRNA processing MENKDALDIG MENKDALDIGKDDTNTSEADVSKNET... |
DNA replication initiation DNA replication, synthesis of RNA primer | alpha DNA polymerase:primase complex; chromatin; cytoplasm; nucleus | DNA primase activity metal ion binding | Schizosaccharomyces pombe | DNA replication DNA-directed RNA polymerase Magnesium Manganese Metal-binding Nucleotidyltransferase Nucleus Primosome Reference proteome Transcription Transferase Zinc | MTVQIDELDD | MTVQIDELDDKDLDEIIANGTLDGAKQGAVDSETMIQYYRHLFPWKYLFQWLNHGPVVTNDFAHREFAFTLPNDAYIRYLSFSNWEELKKEALNLCPSRFEVGPVYSANPRDRKTIRKSTFHPLKKELVFDIDMTDYDDVRTCCSKTNICEKCWPFITIAVQVLDICFHEDFGFKHILWVYSGRRGIHAWICDEIACSLDDRSRRMIASYLQVVVGNPQGGVRLINNLKRPLHPHLTRSLNILKSAFVKIVLEDQDPWASKEGAENLLKLLPDKDLASALRKKWEVDPERSSKNKWSDIDTVLASGSIASISPSVIAIAK... | DNA replication initiation DNA replication, synthesis of RNA primer alpha DNA polymerase:primase complex; chromatin; cytoplasm; nucleus DNA primase activity metal ion binding Schizosaccharomyces pombe DNA replication DNA-directed RNA polymerase Magnesium Manganese Metal-binding Nucleotidyltransferase Nucleus Primosome... |
DNA replication initiation double-strand break repair via break-induced replication mitotic DNA replication initiation mitotic DNA replication preinitiation complex assembly | cytoplasm; DNA replication preinitiation complex; nuclear replication fork; nucleus | DNA replication origin binding single-stranded DNA binding | Schizosaccharomyces pombe | Cell cycle Cytoplasm DNA replication Nucleus Phosphoprotein Reference proteome | MHDESRTKQI | MHDESRTKQISSIKALLKKWEHEYVHTNNCKPSKEDVKKQPEIALLYKQYYELKRESSITPKKAKTKVDFKFQTPTKQRAETEANESPKAPRNDYLQVTPKTVDKSLLGPTPQLSRRVLNLLEDMSPIADSHVDQISDIKHNTSEISSTMIPTTPSKNPEPVAQHTPTVLETPSSYRLQVYTSPNLLRVNAPCRKSLSEMLRELKDIEDDYGSNEEKILQEFESFSSSSSESLVDRDISQPMKKKIKRQNRLVKLPPSMNLSKSHLEGLPEIDEDAENGIDDNEDTTASKDSSPFLDLQSERQNKKIMRNGLVIGKQVSQ... | DNA replication initiation double-strand break repair via break-induced replication mitotic DNA replication initiation mitotic DNA replication preinitiation complex assembly cytoplasm; DNA replication preinitiation complex; nuclear replication fork; nucleus DNA replication origin binding single-stranded DNA binding Sch... |
endosomal vesicle fusion Golgi to vacuole transport intracellular protein transport vacuole fusion vesicle docking vesicle fusion | endomembrane system; Golgi membrane; Golgi trans cisterna; late endosome; late endosome membrane; SNARE complex; trans-Golgi network | SNAP receptor activity SNARE binding | Schizosaccharomyces pombe | Coiled coil Golgi apparatus Membrane Protein transport Reference proteome Transport | MSNLLLIIDS | MSNLLLIIDSVSQKIRDRRKLEEFGQNPDEEIESSLKDVRQELQKLNEEQSRLEKNAQIPEYRVRESEAFLIRMQRRLESAEEEFEKQRRASSIPADGTSAFSANPQVASTNNKLTPLPSLQKTTSSSEGSDIEMEAMYPVDGNDPDPINVNVLAQMHQQMLNEQEESLGGIEASVQRQKRMGYAMNTELSEQNVLLDNMNNDADRIERRFDHAKNRLNKVSRKAKQYPRCFIILLLCALLLLVASI | endosomal vesicle fusion Golgi to vacuole transport intracellular protein transport vacuole fusion vesicle docking vesicle fusion endomembrane system; Golgi membrane; Golgi trans cisterna; late endosome; late endosome membrane; SNARE complex; trans-Golgi network SNAP receptor activity SNARE binding Schizosaccharomyces ... |
ergosterol biosynthetic process farnesyl diphosphate biosynthetic process geranyl diphosphate biosynthetic process geranylgeranyl diphosphate biosynthetic process | cytoplasm; cytosol; endoplasmic reticulum; nucleus | dimethylallyltranstransferase activity geranyltranstransferase activity metal ion binding | Schizosaccharomyces pombe | Cytoplasm Isoprene biosynthesis Lipid biosynthesis Lipid metabolism Magnesium Metal-binding Nucleus Reference proteome Transferase | MSAVDKRAKF | MSAVDKRAKFESALPVFVDEIVNYLKTINIPDDVTEWYKNSLFHNTLGGKYNRGLSVIDSYEILLGHPLDEAAYMKAAVLGWMVELLQSFFLIADDIMDASKTRRGQPCWYLMPGVGNIAINDAFMVESAIYFLLKKHFRQESCYVDLIELFHDVTFQTELGQQLDLLTAPEDSVDLSKFSLQKHSFIVIYKTAFYSFYLPVALAMHLAGVATPENLKCAQDILIILGKYFQVQDDYLDCYGDPTVTGKIGTDILDNKCSWIINLALAKCTPEQRVILDDNYGRKDSESEKRVKAVFEELNIRGEFENYEESEVSEIKKL... | ergosterol biosynthetic process farnesyl diphosphate biosynthetic process geranyl diphosphate biosynthetic process geranylgeranyl diphosphate biosynthetic process cytoplasm; cytosol; endoplasmic reticulum; nucleus dimethylallyltranstransferase activity geranyltranstransferase activity metal ion binding Schizosaccharomy... |
endocytic recycling mitophagy piecemeal microautophagy of the nucleus protein targeting to vacuole protein transport reticulophagy | autophagosome; cytosol; early endosome; endosome membrane; Golgi apparatus; phagophore assembly site; phagophore assembly site membrane | phosphatidylinositol-3-phosphate binding | Schizosaccharomyces pombe | Autophagy Coiled coil Cytoplasm Endosome Lipid-binding Membrane Phosphoprotein Protein transport Reference proteome Transport | MSDSVNLDEP | MSDSVNLDEPSTNSTHFLQCLVTEPRKELQGSRDTHVSYLIITKTNLSIFTRAECKVRRRFSDFVKLQEILSRMNEDCVVPPLPAKHKLEYIKGGRFSDNFINRRAKLLNRYITRCALHPVLHQSPHFIAFLENPNWNNYVRFFIQPKLNNTSKLDEISDSLLNAFSKLKEEPTEFDIQRDHVQQFMFGISNLEGSIQKLLRLEKALESDYEDVSIQFDRLASLDQALDVPIESIQNALQQTGTEYANLTEKLTLLLDTIKDVESYAHSLKELLKRRDQKQQDVEALQEYSAKLSLERDKISSGGSNGFSLSKTLDDLRG... | endocytic recycling mitophagy piecemeal microautophagy of the nucleus protein targeting to vacuole protein transport reticulophagy autophagosome; cytosol; early endosome; endosome membrane; Golgi apparatus; phagophore assembly site; phagophore assembly site membrane phosphatidylinositol-3-phosphate binding Schizosaccha... |
mitotic telomere maintenance via semi-conservative replication protein localization to chromosome, telomeric region telomere capping telomere maintenance telomere maintenance via telomerase telomere-telomerase complex assembly | chromosome, telomeric repeat region; shelterin complex; telomere cap complex | telomeric DNA binding | Schizosaccharomyces pombe | 3D-structure Chromosome DNA-binding Nucleus Reference proteome Telomere | MSNCLKHPWL | MSNCLKHPWLENGLLNLIKNADVLPIRVFKCQPLQIFEYIRYEHPIRCKLSDTEFYIEAEFSSQSISDLNNFTEKRITSLRGGIVTLGNFLIHLIPSQSGIIPWIQVESFNFQGCEGAVFGNPKAITTSALFNALLQSPYLAALANEFNRSIKEGSSYQEASLSQQEKPNDNTSNSRDIKNNIQFHWKNMTSLSIEECIIPKGQQLILEKESEENTTHGIYLEERKMAQGLHNSVSETPEVKQEDNDEDLDAYSWSSSTDSAGEIPSLPTNRKILEKIAEKPPPFESPLEDDETPDQTNEHEANQVNVSQLPLNPRGSGI... | mitotic telomere maintenance via semi-conservative replication protein localization to chromosome, telomeric region telomere capping telomere maintenance telomere maintenance via telomerase telomere-telomerase complex assembly chromosome, telomeric repeat region; shelterin complex; telomere cap complex telomeric DNA bi... |
autophagosome assembly cellular response to nitrogen starvation macroautophagy mitophagy piecemeal microautophagy of the nucleus positive regulation of protein phosphorylation protein transport reticulophagy | Atg1/ULK1 kinase complex; cytoplasm; fungal-type vacuole membrane; nucleus; phagophore assembly site; phagophore assembly site membrane | molecular adaptor activity protein kinase binding protein serine/threonine kinase activator activity | Schizosaccharomyces pombe | Autophagy Coiled coil Membrane Phosphoprotein Protein transport Reference proteome Transport Vacuole | MRFRLNDSFS | MRFRLNDSFSGKSWTIDNVQWTPQNLVAWIMELNIGLSDEAKLLLPNGMSLNETVLNSESDVVIYVLDQNLLTFTYDGDKIPSIPSLKGQPISNVLTGIIADSSSDQWKDKISKCLSLLSDILESSSKIHNQLSVCHDEYSTSIVSPEVAMNYLQRRQSGMKDLLFVFYERLDRVSVSDLLHDFLALPTGSLPITPLKILSTNWTKLDSWLNSISARYAEAQKRVQQCIGAANSIIVSPFKEVPSIKEGDDAYYHLRSVAQDAANILQEILKIESTSTTSQIKPKCNYETEITDCMEKLQSNLSELKSSRKSSLISLKSF... | autophagosome assembly cellular response to nitrogen starvation macroautophagy mitophagy piecemeal microautophagy of the nucleus positive regulation of protein phosphorylation protein transport reticulophagy Atg1/ULK1 kinase complex; cytoplasm; fungal-type vacuole membrane; nucleus; phagophore assembly site; phagophore... |
positive regulation of induction of conjugation with cellular fusion positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II response to stimulus | chromatin; nucleus; RNA polymerase II transcription regulator complex | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity RNA polymerase II cis-regulatory region sequence-specific DNA binding | Schizosaccharomyces pombe | DNA-binding Nucleus Phosphoprotein Reference proteome Sensory transduction Transcription Transcription regulation | MPSSNGSSDF | MPSSNGSSDFVRKLFNMLEEPEYRHILRWSDSGDSFIVLDTNEFTKTILPRHFKHSNFASFVRQLNKYDFHKVRHEEGAPSIYGEGAWEFRHDDFQLHHKDLLDNIKRKAPSKRNLANENTAPVIENLKQQVDSILDFQKLLDRNLSGLATSYQTILLKMFELKRGIESRDLLMSSIISYLCDLEGSTQRQANPGAMFVPSHPLQELLNAYQALAKGQVATTSPQQIPNQIQQASAATTASSKMTVDTNLGTAQPSLYNTPSSDYELANQEKPADSMASAASLNTPLSSNDHSLNPHAHGSYPMYEKFQPIQHPNPGSFT... | positive regulation of induction of conjugation with cellular fusion positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II response to stimulus chromatin; nucleus; RNA polymerase II transcription regulator complex DNA-binding transcription activator activity, RNA pol... |
pyridoxal biosynthetic process vitamin B6 catabolic process | cytoplasm; cytosol; nucleus | aldo-keto reductase (NADP) activity oxidoreductase activity pyridoxine:NADP 4-dehydrogenase activity | Schizosaccharomyces pombe | Cytoplasm Direct protein sequencing NADP Oxidoreductase Phosphoprotein Reference proteome | MPIVSGFKVG | MPIVSGFKVGPIGFGLMGLTWKPKQTPDEEAFEVMNYALSQGSNYWDAGEFYGVDPPTSNLDLLARYFEKYPENANKVFLSVKGGLDFKTLVPDGNPDFVSKSVENVIAHLRGTKKLDLFQCARVDPNVPIETTMKTLKGFVDSGKISCVGLSEVSAETIKRAHAVVPIAAVEVEYSLFSRDIETNGIMDICRKLSIPIIAYSPFCRGLLTGRIKTVEDLKEFAKSFPFLEYLDRFSPDVFAKNLPFLQAVEQLAKKFGMTMPEFSLLFIMASGNGLVIPIPGSTSVSRTKSNLNALNKSLSPEQFKEAKEVLSKYPIYG... | pyridoxal biosynthetic process vitamin B6 catabolic process cytoplasm; cytosol; nucleus aldo-keto reductase (NADP) activity oxidoreductase activity pyridoxine:NADP 4-dehydrogenase activity Schizosaccharomyces pombe Cytoplasm Direct protein sequencing NADP Oxidoreductase Phosphoprotein Reference proteome MPIVSGFKVG MPI... |
cell cycle cell division phosphorylation regulation of protein localization to mitotic spindle pole body septation initiation signaling | cytoplasm; cytosol; mitotic spindle pole body; new mitotic spindle pole body; nucleus | ATP binding protein serine kinase activity protein serine/threonine kinase activity | Schizosaccharomyces pombe | ATP-binding Cell cycle Cell division Cytoplasm Cytoskeleton Kinase Mitosis Nucleotide-binding Reference proteome Serine/threonine-protein kinase Transferase | MYPLNANSYT | MYPLNANSYTLLRKLGSGSFGVVWKARENVSGDIIAIKQIDLETGIDDITDIEQEVFMLSNCNSSNVIQYYGCFVDGYTLWILMEHMDGGSVSGLLKMGRLNEQVISIILREVLYGLNYLHGQNKIHRDIKAANILLSSSTGNVKLADFGVAAQLSNAASRRHTFVGTPFWMAPEVIQQTSYGLAADIWSLGITAIEMANGIPPRATMHPMRVIFEIPQSEPPKLDDHFSPTFRDFVSCCLDLNPNMRWSAKELLQHPFIKSAGTVKDIIPLLVQKENKLFDDSDQSVLEETINNTLKPFEEPIAEGNADIEDWTFETVK... | cell cycle cell division phosphorylation regulation of protein localization to mitotic spindle pole body septation initiation signaling cytoplasm; cytosol; mitotic spindle pole body; new mitotic spindle pole body; nucleus ATP binding protein serine kinase activity protein serine/threonine kinase activity Schizosaccharo... |
mRNA export from nucleus poly(A)+ mRNA export from nucleus protein import into nucleus stalled replication fork localization to nuclear periphery | cytosol; nuclear envelope; nuclear periphery; nuclear pore; nucleus | structural constituent of nuclear pore | Schizosaccharomyces pombe | mRNA transport Nuclear pore complex Nucleus Phosphoprotein Protein transport Reference proteome Translocation Transport | MESKEAKEKG | MESKEAKEKGVNTSDSKGSQIESSISDLREKSQHLFGVLLEPQVPVIQYGLNQLEEKARNLESKVLLTRDGDTKAHYLLAESGMNAEQTRQKIYSIHIHSPWDQLELDKKSLYEQPHTKLYNGQNVVASIENGYQSNVYEFQLRLMKNNGIAWENTKTEFMEDVGKLLHSKDNSGLGTSISMSLRPNLARPLLTASSVKSQSVRSLREVGSNLPIPTGSLTKIDGLNNQLSNDLTRSQTTNIFGFAEKASSFAAAVHKLNEARIRNQACHVWSLFASVSQMVNTEVIQLFDAWSLLAHMIDETRYGMGDFEARHLALDSS... | mRNA export from nucleus poly(A)+ mRNA export from nucleus protein import into nucleus stalled replication fork localization to nuclear periphery cytosol; nuclear envelope; nuclear periphery; nuclear pore; nucleus structural constituent of nuclear pore Schizosaccharomyces pombe mRNA transport Nuclear pore complex Nucl... |
cell redox homeostasis cellular response to oxidative stress hydrogen peroxide catabolic process protein refolding | cytoplasm; cytosol; mitochondrion; nucleus; peroxisome | peroxidase activity unfolded protein binding | Schizosaccharomyces pombe | Antioxidant Cytoplasm Disulfide bond Nucleus Oxidoreductase Peroxidase Redox-active center Reference proteome | MVAVGSTLPK | MVAVGSTLPKVTLWENKPEEVVEFPSQGKFIIVGVPGAFTPPCSSQVPGYIANEKQFAAKGISGIYVVAVNDVFVTKAWKKSFDGGEQSGVHFVADWNGEFTKAFDAGFDASGLLGPLRSKRYAAVVENGKVVKVFIENEVTDVDISSADKVLSSL | cell redox homeostasis cellular response to oxidative stress hydrogen peroxide catabolic process protein refolding cytoplasm; cytosol; mitochondrion; nucleus; peroxisome peroxidase activity unfolded protein binding Schizosaccharomyces pombe Antioxidant Cytoplasm Disulfide bond Nucleus Oxidoreductase Peroxidase Redox-a... |
nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts | chromatin; cytoplasm; Mei2 nuclear dot complex; nuclear body; nuclear exosome focus; nucleolar peripheral inclusion body; nucleolus; nucleoplasm; nucleus | lncRNA binding mRNA binding poly(A) binding | Schizosaccharomyces pombe | Nucleus Reference proteome RNA-binding | MSDQDALDTQ | MSDQDALDTQEKELLEMKERVAEMEAEAAKLRAMQEQLDNETEALRNDKESIDAQSVYVGNVDYSVTPEELQSHFASCGSVNRVTILCDKFTGHPKGFAYIEFSEPSLVPNALLLNGSMLHERPLKVTPKRTNVPGMSRGRGRGRGRGRGRGRGGYRGRARGFAPY | nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts chromatin; cytoplasm; Mei2 nuclear dot complex; nuclear body; nuclear exosome focus; nucleolar peripheral inclusion body; nucleolus; nucleoplasm; nucleus lncRNA binding mRNA binding poly(A) binding Schizosaccharomyces pombe Nucleus Reference prot... |
CDP-choline pathway phosphatidylethanolamine biosynthetic process protein autoprocessing | mitochondrial inner membrane; mitochondrion | phosphatidylserine decarboxylase activity | Schizosaccharomyces pombe | Decarboxylase Lipid biosynthesis Lipid metabolism Lyase Membrane Mitochondrion Mitochondrion inner membrane Phospholipid biosynthesis Phospholipid metabolism Pyruvate Reference proteome Transit peptide Transmembrane Transmembrane helix Zymogen | MLKFHRNVKP | MLKFHRNVKPQFGAFARYSSLGKHNSRKRVGIIRLAYGLTGIGLVGLAGFAWAQDRHEKTYQKKGVQVEGPWQFYVLTTLPLRTLSRWWGYVNRIEIPLWMRVPAFGLYSKIFGCNLTEADPDDVRQYKNLAEFFTRKLKPGARVIDPDAPIVIPADGKILNYGVIEGGQLEQVKGITYSLDALLGDEKLARLKRSHAIPSPDHIPHIRQEEFAKLNGIHYSLQDLMGHDHGERPSHVKDASAQHIDLLSSTKVAAKSQFTLFGSRETNCLYYAVIYLAPGDYHRFHSPTDWVVERRRHFSGELFSVSPFMARRLGNLFI... | CDP-choline pathway phosphatidylethanolamine biosynthetic process protein autoprocessing mitochondrial inner membrane; mitochondrion phosphatidylserine decarboxylase activity Schizosaccharomyces pombe Decarboxylase Lipid biosynthesis Lipid metabolism Lyase Membrane Mitochondrion Mitochondrion inner membrane Phospholip... |
cell division deactivation of mitotic spindle assembly checkpoint lateral attachment of mitotic spindle microtubules to kinetochore microtubule cytoskeleton organization microtubule depolymerization microtubule-based movement mitotic chromosome movement towards spindle pole mitotic metaphase chromosome recapture mitoti... | cortical microtubule; cytoplasm; cytosol; kinesin complex; kinesin I complex; kinetochore; microtubule cytoskeleton; mitotic spindle; mitotic spindle astral microtubule; mitotic spindle midzone; mitotic spindle pole body; nucleus; plus-end kinesin complex; post-anaphase microtubule array | ATP binding ATP hydrolysis activity microtubule binding plus-end-directed microtubule motor activity | Schizosaccharomyces pombe | ATP-binding Cell cycle Cell division Centromere Chromosome Chromosome partition Coiled coil Cytoplasm Cytoskeleton Kinetochore Microtubule Mitosis Motor protein Nucleotide-binding Reference proteome | MSRQSSITVT | MSRQSSITVTVRVRPFSTAESANLIASSDRLSFGTSSSLRNPGSGRQIRRVVKVLDGRVLVFDPPDETTATLSATNRRLSTSQQSLARLSRKSNNSAGFGRDLRYAFDRVFDETATQQQVYERTARPLLDNILDGFNATIFAYGATGCGKTHTISGTMQDPGLIYLTLKELFERMDHLRDEKIFDLRLSYLEIYNETIRDLLVSPTPNQAKPLNLREDADRRITVPGLTSLSPESLEEIIDIIMKGNANRTMSPTEANAASSRSHAVLQVTLIQKPRTAGINEDHTLATLSIIDLAGSERATATKLRGSRLFEGANINKS... | cell division deactivation of mitotic spindle assembly checkpoint lateral attachment of mitotic spindle microtubules to kinetochore microtubule cytoskeleton organization microtubule depolymerization microtubule-based movement mitotic chromosome movement towards spindle pole mitotic metaphase chromosome recapture mitoti... |
cell cycle DNA damage response DNA replication checkpoint signaling gene conversion at mating-type locus mating-type locus imprinting replication fork arrest replication fork processing | chromatin; mitochondrion; nucleus; replication fork protection complex | DNA binding double-stranded DNA binding Y-form DNA binding | Schizosaccharomyces pombe | Cell cycle DNA damage DNA replication inhibitor Nucleus Reference proteome | MSTAASDSGV | MSTAASDSGVEKLVEENKREEVKKNEEEKEFDLGLEENPDSVKKPRKRLAKFDEERLISENGIPKLRKMMRKVKLKGKGHEAKDLKQLLGMYHIWTHELYPRATFDDSISYLKTLGKHRSVKVRRRGWINEIAVENGSDSNASLFTGPSSNSLVNLTSGDPYVQDTADDAFVAQDNDTQLE | cell cycle DNA damage response DNA replication checkpoint signaling gene conversion at mating-type locus mating-type locus imprinting replication fork arrest replication fork processing chromatin; mitochondrion; nucleus; replication fork protection complex DNA binding double-stranded DNA binding Y-form DNA binding Schi... |
nuclear-transcribed mRNA catabolic process P-body assembly RNA folding spliceosomal snRNP assembly telomerase holoenzyme complex assembly | cytosol; Lsm1-7-Pat1 complex; Lsm2-8 complex; nucleolus; nucleus; P-body; spliceosomal complex; spliceosomal tri-snRNP complex; telomerase holoenzyme complex; U2 snRNP; U4/U6 x U5 tri-snRNP complex; U5 snRNP; U6 snRNP | U2 snRNA binding U6 snRNA binding | Schizosaccharomyces pombe | 3D-structure mRNA processing mRNA splicing Nucleus Reference proteome Ribonucleoprotein RNA-binding Spliceosome | MLPLTLLNAT | MLPLTLLNATQGRPILVELKNGETFNGHLENCDNYMNLTLREVIRTMPDGDKFFRLPECYIRGNNIKYLRIQDEVLSQVAKQQAQQRENRGSRFRGRGQRGRGNYGHTAPNRRGRGRGGHM | nuclear-transcribed mRNA catabolic process P-body assembly RNA folding spliceosomal snRNP assembly telomerase holoenzyme complex assembly cytosol; Lsm1-7-Pat1 complex; Lsm2-8 complex; nucleolus; nucleus; P-body; spliceosomal complex; spliceosomal tri-snRNP complex; telomerase holoenzyme complex; U2 snRNP; U4/U6 x U5 tr... |
cellular response to heat cellular response to misfolded protein cellular response to unfolded protein protein folding | cytoplasm; cytosol; nucleus; protein aggregate center | identical protein binding protein folding chaperone unfolded protein binding | Schizosaccharomyces pombe | 3D-structure Cytoplasm Nucleus Reference proteome Stress response | MSLQPFFGFP | MSLQPFFGFPPTVNDLFSDFVSYSPRLNNQIPGELSPSIDVHEGKDTVSVDVELPGVKKEDVQVHYDSGKLTISGEVVNERKNESTEGNQRWSERRFGSFSRTITIPAKIDADRIEANFSNGLLTVTLPKVEKSQTKKQIAIK | cellular response to heat cellular response to misfolded protein cellular response to unfolded protein protein folding cytoplasm; cytosol; nucleus; protein aggregate center identical protein binding protein folding chaperone unfolded protein binding Schizosaccharomyces pombe 3D-structure Cytoplasm Nucleus Reference pr... |
isoleucine biosynthetic process leucine biosynthetic process valine biosynthetic process | cytosol; mitochondrial matrix; mitochondrion; nucleus | branched-chain-amino-acid transaminase activity L-isoleucine transaminase activity L-leucine transaminase activity L-leucine:2-oxoglutarate aminotransferase activity L-valine transaminase activity pyridoxal phosphate binding | Schizosaccharomyces pombe | Amino-acid biosynthesis Aminotransferase Branched-chain amino acid biosynthesis Cytoplasm Mitochondrion Nucleus Pyridoxal phosphate Reference proteome Transferase Transit peptide | MSLMFLRRAG | MSLMFLRRAGNIKGRNIRFALQRGSVGYSQQSSEACKNFLNTTQLRTMVQTAALHGPKPMDSSHIKVTNVKELKPLPEWKSLKFGENFTDHMLIMKWNREKGWSTPEIVPFGKLCFHPASSVFHYGFECFEGMKAFRDEKGVPRLFRPIKNAERMLSTGTRISLPSFDPAELAEIIRKFVAHENRWVPDQRGYSLYIRPTFIGTDEALGVHHCDNAMLYVIASPVGPYYSSGFKAVKLCCSEESVRAWPGGTGHYKLGGNYAPSVLPQKEAAKKGYAQILWLYGDEDYITEVGTMNCFTVWINKNGEKEIITAPLDGMIL... | isoleucine biosynthetic process leucine biosynthetic process valine biosynthetic process cytosol; mitochondrial matrix; mitochondrion; nucleus branched-chain-amino-acid transaminase activity L-isoleucine transaminase activity L-leucine transaminase activity L-leucine:2-oxoglutarate aminotransferase activity L-valine tr... |
cellulose catabolic process | extracellular region | cellulase activity cellulose binding | Hypocrea jecorina | Carbohydrate metabolism Cellulose degradation Disulfide bond Glycoprotein Glycosidase Hydrolase Polysaccharide degradation Secreted Signal | MIQKLSNLLV | MIQKLSNLLVTALAVATGVVGHGHINDIVINGVWYQAYDPTTFPYESNPPIVVGWTAADLDNGFVSPDAYQNPDIICHKNATNAKGHASVKAGDTILFQWVPVPWPHPGPIVDYLANCNGDCETVDKTTLEFFKIDGVGLLSGGDPGTWASDVLISNNNTWVVKIPDNLAPGNYVLRHEIIALHSAGQANGAQNYPQCFNIAVSGSGSLQPSGVLGTDLYHATDPGVLINIYTSPLNYIIPGPTVVSGLPTSVAQGSSAATATASATVPGGGSGPTSRTTTTARTTQASSRPSSTPPATTSAPAGGPTQTLYGQCGGSGY... | cellulose catabolic process extracellular region cellulase activity cellulose binding Hypocrea jecorina Carbohydrate metabolism Cellulose degradation Disulfide bond Glycoprotein Glycosidase Hydrolase Polysaccharide degradation Secreted Signal MIQKLSNLLV MIQKLSNLLVTALAVATGVVGHGHINDIVINGVWYQAYDPTTFPYESNPPIVVGWTAADLDNGFVS... |
cell division meiosis I spindle assembly checkpoint signaling meiotic spindle assembly checkpoint signaling mitotic spindle assembly checkpoint signaling negative regulation of mitotic metaphase/anaphase transition | chromatin; cytoplasm; kinetochore; mitotic checkpoint complex; mitotic spindle microtubule; mitotic spindle pole body; nuclear periphery; nucleoplasm | anaphase-promoting complex binding | Schizosaccharomyces pombe | 3D-structure Cell cycle Cell division Mitosis Nucleus Reference proteome | MSSVPIRTNF | MSSVPIRTNFSLKGSSKLVSEFFEYAVNSILFQRGIYPAEDFKVVRKYGLNMLVSVDEEVKTYIRKIVSQLHKWMFAKKIQKLILVITSKCSGEDLERWQFNVEMVDTADQFQNIGNKEDELRVQKEIQALIRQITATVTFLPQLEEQCTFNVLVYADKDSEVPTDWVDSDPRILRDAEQVQLRSFSTSMHKIDCQVAYRVNP | cell division meiosis I spindle assembly checkpoint signaling meiotic spindle assembly checkpoint signaling mitotic spindle assembly checkpoint signaling negative regulation of mitotic metaphase/anaphase transition chromatin; cytoplasm; kinetochore; mitotic checkpoint complex; mitotic spindle microtubule; mitotic spind... |
conidium formation melanin biosynthetic process pigment biosynthetic process sporulation resulting in formation of a cellular spore | endosome | scytalone dehydratase activity | Aspergillus fumigatus | Conidiation Endosome Lyase Reference proteome Sporulation | MVEKKPNLTL | MVEKKPNLTLEFHDYLALKKVLFDWADSYDAKDWDRLRSIIAPTLTVDYRQIGLRKWDDMPAEDYMAMISDMDFLGDPTVKTQHLLGESWWEKISDTEVIGHHQLRAAHQVYTDSTLQTVKLKGHGHATNEHYYRKVDGVWKFAGLKPTVRWNEYQFEDVFRAAKPSV | conidium formation melanin biosynthetic process pigment biosynthetic process sporulation resulting in formation of a cellular spore endosome scytalone dehydratase activity Aspergillus fumigatus Conidiation Endosome Lyase Reference proteome Sporulation MVEKKPNLTL MVEKKPNLTLEFHDYLALKKVLFDWADSYDAKDWDRLRSIIAPTLTVDYRQIGLRK... |
sterol biosynthetic process | membrane | heme binding iron ion binding sterol 14-demethylase activity | Uncinula necator | Heme Iron Lipid biosynthesis Lipid metabolism Membrane Metal-binding Monooxygenase Oxidoreductase Steroid biosynthesis Steroid metabolism Sterol biosynthesis Sterol metabolism | MYIADILSDL | MYIADILSDLLTQQTTRYGWIFMVTSIAFSIILLAVGLNVLSQLLFRRPYEPPVVFHWFPIIGSTISYGIDPYKFYFDCRAKYGDIFTFILLGKKVTVYLGLQGNNFILNGKLKDVNAEEIYTNLTTPVFGRDVVYDCPNSKLMEQKKFMKTALTIEAFHSYVTIIQNEVEAYINNCVSFQGESGTVNISKVMAEITIYTASHALQGEEVRENFDSSFAALYHDLDMGFTPINFTFYWAPLPWNRARDHAQRTVARTYMNIIQARREEKRSGENKHDIMWELMRSTYKDGTPVPDREIAHMMIALLMAGQHSSSSTSSWI... | sterol biosynthetic process membrane heme binding iron ion binding sterol 14-demethylase activity Uncinula necator Heme Iron Lipid biosynthesis Lipid metabolism Membrane Metal-binding Monooxygenase Oxidoreductase Steroid biosynthesis Steroid metabolism Sterol biosynthesis Sterol metabolism MYIADILSDL MYIADILSDLLTQQTTRY... |
cell redox homeostasis cellular detoxification of hydrogen peroxide cellular response to reactive oxygen species hydrogen peroxide catabolic process L-methionine salvage from methionine sulphoxide sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) | cytoplasm; cytosol; nucleus | antioxidant activity protein-disulfide reductase activity | Schizosaccharomyces pombe | Disulfide bond Electron transport Redox-active center Reference proteome Transport | MVKQVSDSSE | MVKQVSDSSEFKSIVCQDKLVVVDFFATWCGPCKAIAPKFEQFSNTYSDATFIKVDVDQLSEIAAEAGVHAMPSFFLYKNGEKIEEIVGANPAKLEASIKANL | cell redox homeostasis cellular detoxification of hydrogen peroxide cellular response to reactive oxygen species hydrogen peroxide catabolic process L-methionine salvage from methionine sulphoxide sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) cytoplasm; cytos... |
maintenance of translational fidelity positive regulation of transcription by RNA polymerase II rescue of stalled ribosome | mitochondrion; nucleus | DNA binding ribosome binding transcription coactivator activity | Saccharomyces cerevisiae | 3D-structure Cytoplasm Direct protein sequencing DNA-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MSDWDTNTII | MSDWDTNTIIGSRARAGGSGPRANVARSQGQINAARRQGLVVSVDKKYGSTNTRGDNEGQRLTKVDRETDIVKPKKLDPNVGRAISRARTDKKMSQKDLATKINEKPTVVNDYEAARAIPNQQVLSKLERALGVKLRGNNIGSPLGAPKKK | maintenance of translational fidelity positive regulation of transcription by RNA polymerase II rescue of stalled ribosome mitochondrion; nucleus DNA binding ribosome binding transcription coactivator activity Saccharomyces cerevisiae 3D-structure Cytoplasm Direct protein sequencing DNA-binding Nucleus Phosphoprotein ... |
chromatin remodeling epigenetic regulation of gene expression positive regulation of DNA-templated transcription regulation of transcription by RNA polymerase II transcription initiation-coupled chromatin remodeling | chromatin; cytoplasm; RSC-type complex; SWI/SNF complex | DNA binding histone binding zinc ion binding | Schizosaccharomyces pombe | Chromatin regulator Cytoplasm DNA-binding Metal-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Zinc Zinc-finger | MTLDQVRIPF | MTLDQVRIPFLVEQTYPIIVPSYAGWFDMSKIHDIERRSNPEFFNGKSPLKTPSIYKDYRDFMINSYRLEPNEYLTVTACRRNLVGDVCAIIRVHAFLEQWGLINYQIDPETRPAFRLPPISGHVQAISNTPIVTQEMLAQHPPPSTVGGSSSQEFVKLEEKHYSPSLNAMEQTSPKEEDEKSDKVPRVDKVCFTCGVNCSQTWYHNLKNKKYDICPNCYKQGRFSSSFNSSDFLCMDAIDFNHDEEKPWSNQETLLLLEAIETYGDDWNQIALHVGSRTKEQCLIHFLQIPIEDPYRQKLQGDFSPFKKGFLPFDENEN... | chromatin remodeling epigenetic regulation of gene expression positive regulation of DNA-templated transcription regulation of transcription by RNA polymerase II transcription initiation-coupled chromatin remodeling chromatin; cytoplasm; RSC-type complex; SWI/SNF complex DNA binding histone binding zinc ion binding Sch... |
chemical synaptic transmission | glutamatergic synapse; plasma membrane; postsynaptic density; postsynaptic specialization | molecular adaptor activity protein-containing complex binding | Homo sapiens | 3D-structure Alternative splicing Cell membrane Membrane Phosphoprotein Reference proteome Synapse Ubl conjugation | MKGLSGSRSH | MKGLSGSRSHHHGVTCDSACDSLSHHSDRKPYLLSPVEHHPADHPYYTQRNSFQAECVGPFSDPLASSTFPRRHYTSQQELKDECALVPRTLATKANRIPANLLDQFERQLPLSRDGYHTLQYKRTAVEHRSDSPGRIRHLVHSVQKLFTKSHSLEGPSKGSVNGGKASPDEAQAARYGKRSKSKERRAEPKARPSTSPGWWSSDDNLDGDMCIYHAPSGVMTMGRCPDRSASQYFLEAYNTISEQAVKASRSNNDVKCSTCANLPVSLDTPLLKKSAWSSTLTVSRAREVYQKASVNMDQAMVKSESCQQERSCQYLQV... | chemical synaptic transmission glutamatergic synapse; plasma membrane; postsynaptic density; postsynaptic specialization molecular adaptor activity protein-containing complex binding Homo sapiens 3D-structure Alternative splicing Cell membrane Membrane Phosphoprotein Reference proteome Synapse Ubl conjugation MKGLSGSRS... |
actin cytoskeleton organization antigen receptor-mediated signaling pathway B cell receptor signaling pathway B-1 B cell homeostasis brown fat cell differentiation cytokine-mediated signaling pathway insulin receptor signaling pathway intracellular signal transduction nervous system development regulation of metabolic ... | actin filament; cytoplasm; cytosol; plasma membrane; ruffle; stress fiber | identical protein binding SH2 domain binding signaling adaptor activity transmembrane receptor protein tyrosine kinase adaptor activity | Homo sapiens | 3D-structure Alternative splicing Cell membrane Cytoplasm Membrane Phosphoprotein Reference proteome SH2 domain | MNGAGPGPAA | MNGAGPGPAAAAPVPVPVPVPDWRQFCELHAQAAAVDFAHKFCRFLRDNPAYDTPDAGASFSRHFAANFLDVFGEEVRRVLVAGPTTRGAAVSAEAMEPELADTSALKAAPYGHSRSSEDVSTHAATKARVRKGFSLRNMSLCVVDGVRDMWHRRASPEPDAAAAPRTAEPRDKWTRRLRLSRTLAAKVELVDIQREGALRFMVADDAAAGSGGSAQWQKCRLLLRRAVAEERFRLEFFVPPKASRPKVSIPLSAIIEVRTTMPLEMPEKDNTFVLKVENGAEYILETIDSLQKHSWVADIQGCVDPGDSEEDTELSCTR... | actin cytoskeleton organization antigen receptor-mediated signaling pathway B cell receptor signaling pathway B-1 B cell homeostasis brown fat cell differentiation cytokine-mediated signaling pathway insulin receptor signaling pathway intracellular signal transduction nervous system development regulation of metabolic ... |
bicellular tight junction assembly calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules cell adhesion circadian rhythm establishment of skin barrier female pregnancy positive regulation of cell migration positive regulation of metallopeptidase activity positive regulation of wound healing ... | apical plasma membrane; apicolateral plasma membrane; basal plasma membrane; bicellular tight junction; cell-cell junction; chloride channel complex; lateral plasma membrane; plasma membrane; tight junction | chloride channel activity identical protein binding structural molecule activity transmembrane signaling receptor activity | Homo sapiens | 3D-structure Cell junction Cell membrane Chloride Chloride channel Disulfide bond Ion channel Ion transport Membrane Phosphoprotein Reference proteome Tight junction Transmembrane Transmembrane helix Transport Williams-Beuren syndrome | MASMGLQVMG | MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTGQMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIVAGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGLLCCNCPPRTDKPYSAKYSAARSAAASNYV | bicellular tight junction assembly calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules cell adhesion circadian rhythm establishment of skin barrier female pregnancy positive regulation of cell migration positive regulation of metallopeptidase activity positive regulation of wound healing ... |
androgen receptor signaling pathway ceramide metabolic process intracellular steroid hormone receptor signaling pathway negative regulation of cell population proliferation phospholipid dephosphorylation phospholipid metabolic process protein kinase C-activating G protein-coupled receptor signaling pathway regulation o... | apical plasma membrane; caveola; extracellular exosome; membrane; membrane raft; plasma membrane | ceramide-1-phosphate phosphatase activity diacylglycerol diphosphate phosphatase activity lipid phosphatase activity phosphatidate phosphatase activity sphingosine-1-phosphate phosphatase activity | Homo sapiens | Alternative splicing Cell membrane Glycoprotein Hydrolase Lipid metabolism Membrane Reference proteome Transmembrane Transmembrane helix | MFDKTRLPYV | MFDKTRLPYVALDVLCVLLAGLPFAILTSRHTPFQRGVFCNDESIKYPYKEDTIPYALLGGIIIPFSIIVIILGETLSVYCNLLHSNSFIRNNYIATIYKAIGTFLFGAAASQSLTDIAKYSIGRLRPHFLDVCDPDWSKINCSDGYIEYYICRGNAERVKEGRLSFYSGHSSFSMYCMLFVALYLQARMKGDWARLLRPTLQFGLVAVSIYVGLSRVSDYKHHWSDVLTGLIQGALVAILVAVYVSDFFKERTSFKERKEEDSHTTLHETPTTGNHYPSNHQP | androgen receptor signaling pathway ceramide metabolic process intracellular steroid hormone receptor signaling pathway negative regulation of cell population proliferation phospholipid dephosphorylation phospholipid metabolic process protein kinase C-activating G protein-coupled receptor signaling pathway regulation o... |
Bergmann glial cell differentiation blood vessel development cell-cell adhesion mediated by integrin ceramide metabolic process gastrulation with mouth forming second homotypic cell-cell adhesion integrin-mediated signaling pathway negative regulation of protein phosphorylation phospholipid dephosphorylation phospholip... | adherens junction; basolateral plasma membrane; endoplasmic reticulum exit site; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment membrane; Golgi apparatus; Golgi membrane; membrane; membrane raft; plasma membrane; trans-Golgi network | ceramide-1-phosphate phosphatase activity integrin binding phosphatidate phosphatase activity sphingosine-1-phosphate phosphatase activity | Homo sapiens | Cell membrane Endoplasmic reticulum Glycoprotein Golgi apparatus Hydrolase Lipid metabolism Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix | MQNYKYDKAI | MQNYKYDKAIVPESKNGGSPALNNNPRRSGSKRVLLICLDLFCLFMAGLPFLIIETSTIKPYHRGFYCNDESIKYPLKTGETINDAVLCAVGIVIAILAIITGEFYRIYYLKKSRSTIQNPYVAALYKQVGCFLFGCAISQSFTDIAKVSIGRLRPHFLSVCNPDFSQINCSEGYIQNYRCRGDDSKVQEARKSFFSGHASFSMYTMLYLVLYLQARFTWRGARLLRPLLQFTLIMMAFYTGLSRVSDHKHHPSDVLAGFAQGALVACCIVFFVSDLFKTKTTLSLPAPAIRKEILSPVDIIDRNNHHNMM | Bergmann glial cell differentiation blood vessel development cell-cell adhesion mediated by integrin ceramide metabolic process gastrulation with mouth forming second homotypic cell-cell adhesion integrin-mediated signaling pathway negative regulation of protein phosphorylation phospholipid dephosphorylation phospholip... |
anterior/posterior pattern specification circadian regulation of gene expression circadian rhythm entrainment of circadian clock by photoperiod negative regulation of DNA-binding transcription factor activity negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II re... | chromatin; cytoplasm; nuclear body; nucleus | bHLH transcription factor binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific E-box binding MRF binding protein domain specific binding protein heterodimerization activity protein... | Homo sapiens | Biological rhythms Cytoplasm DNA-binding Isopeptide bond Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation Ubl conjugation | MERIPSAQPP | MERIPSAQPPPACLPKAPGLEHGDLPGMYPAHMYQVYKSRRGIKRSEDSKETYKLPHRLIEKKRRDRINECIAQLKDLLPEHLKLTTLGHLEKAVVLELTLKHVKALTNLIDQQQQKIIALQSGLQAGELSGRNVETGQEMFCSGFQTCAREVLQYLAKHENTRDLKSSQLVTHLHRVVSELLQGGTSRKPSDPAPKVMDFKEKPSSPAKGSEGPGKNCVPVIQRTFAHSSGEQSGSDTDTDSGYGGESEKGDLRSEQPCFKSDHGRRFTMGERIGAIKQESEEPPTKKNRMQLSDDEGHFTSSDLISSPFLGPHPHQPP... | anterior/posterior pattern specification circadian regulation of gene expression circadian rhythm entrainment of circadian clock by photoperiod negative regulation of DNA-binding transcription factor activity negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II re... |
cellular response to hormone stimulus growth hormone receptor signaling pathway intracellular signal transduction lactation mammary gland alveolus development negative regulation of apoptotic process negative regulation of multicellular organism growth negative regulation of receptor signaling pathway via JAK-STAT phos... | cytoplasm; cytosol; phosphatidylinositol 3-kinase complex | 1-phosphatidylinositol-3-kinase regulator activity growth hormone receptor binding insulin-like growth factor receptor binding JAK pathway signal transduction adaptor activity | Homo sapiens | 3D-structure Growth regulation Isopeptide bond Phosphoprotein Reference proteome SH2 domain Signal transduction inhibitor Ubl conjugation Ubl conjugation pathway | MTLRCLEPSG | MTLRCLEPSGNGGEGTRSQWGTAGSAEEPSPQAARLAKALRELGQTGWYWGSMTVNEAKEKLKEAPEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGKFRLDSIICVKSKLKQFDSVVHLIDYYVQMCKDKRTGPEAPRNGTVHLYLTKPLYTSAPSLQHLCRLTINKCTGAIWGLPLPTRLKDYLEEYKFQV | cellular response to hormone stimulus growth hormone receptor signaling pathway intracellular signal transduction lactation mammary gland alveolus development negative regulation of apoptotic process negative regulation of multicellular organism growth negative regulation of receptor signaling pathway via JAK-STAT phos... |
animal organ development intracellular signal transduction nervous system development signal transduction | extracellular region; extracellular space; plasma membrane | growth factor activity signaling receptor binding | Homo sapiens | Alternative splicing Cell membrane Disulfide bond EGF-like domain Glycoprotein Growth factor Immunoglobulin domain Membrane Reference proteome Secreted Transmembrane Transmembrane helix | MRQVCCSALP | MRQVCCSALPPPPLEKGRCSSYSDSSSSSSERSSSSSSSSSESGSSSRSSSNNSSISRPAAPPEPRPQQQPQPRSPAARRAAARSRAAAAGGMRRDPAPGFSMLLFGVSLACYSPSLKSVQDQAYKAPVVVEGKVQGLVPAGGSSSNSTREPPASGRVALVKVLDKWPLRSGGLQREQVISVGSCVPLERNQRYIFFLEPTEQPLVFKTAFAPLDTNGKNLKKEVGKILCTDCATRPKLKKMKSQTGQVGEKQSLKCEAAAGNPQPSYRWFKDGKELNRSRDIRIKYGNGRKNSRLQFNKVKVEDAGEYVCEAENILGKD... | animal organ development intracellular signal transduction nervous system development signal transduction extracellular region; extracellular space; plasma membrane growth factor activity signaling receptor binding Homo sapiens Alternative splicing Cell membrane Disulfide bond EGF-like domain Glycoprotein Growth factor... |
intracellular signal transduction negative regulation of signal transduction phosphatidylinositol phosphate biosynthetic process protein ubiquitination | cytosol; nucleus; phosphatidylinositol 3-kinase complex; plasma membrane | 1-phosphatidylinositol-3-kinase regulator activity SH3 domain binding | Homo sapiens | Alternative splicing Cell membrane Cytoplasm Growth regulation Membrane Nucleus Reference proteome SH2 domain Signal transduction inhibitor Ubl conjugation pathway | MVFRNVGRPP | MVFRNVGRPPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQPAGPGVKTVGGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQQQQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGELAASAASLTDMGGSAGRELDAGRKPKLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLD... | intracellular signal transduction negative regulation of signal transduction phosphatidylinositol phosphate biosynthetic process protein ubiquitination cytosol; nucleus; phosphatidylinositol 3-kinase complex; plasma membrane 1-phosphatidylinositol-3-kinase regulator activity SH3 domain binding Homo sapiens Alternative ... |
cell cycle DNA-templated DNA replication positive regulation of protein phosphorylation regulation of transcription by RNA polymerase II | chromatin; cytoplasm; cytosol; nucleoplasm; nucleus; NuRD complex; perinuclear region of cytoplasm | DNA polymerase binding | Homo sapiens | 3D-structure Alternative splicing Cell cycle Chromosome Disulfide bond Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Tumor suppressor | MSYKPNLAAH | MSYKPNLAAHMPAAALNAAGSVHSPSTSMATSSQYRQLLSDYGPPSLGYTQGTGNSQVPQSKYAELLAIIEELGKEIRPTYAGSKSAMERLKRGIIHARGLVRECLAETERNARS | cell cycle DNA-templated DNA replication positive regulation of protein phosphorylation regulation of transcription by RNA polymerase II chromatin; cytoplasm; cytosol; nucleoplasm; nucleus; NuRD complex; perinuclear region of cytoplasm DNA polymerase binding Homo sapiens 3D-structure Alternative splicing Cell cycle Chr... |
glycerol transmembrane transport water transport | basolateral plasma membrane; cell cortex; cell-cell junction; cytoplasm; cytoplasmic vesicle membrane; lipid droplet; plasma membrane | glycerol channel activity urea transmembrane transporter activity water channel activity | Homo sapiens | 3D-structure Alternative splicing Cell membrane Cytoplasm Cytoplasmic vesicle Lipid droplet Membrane Phosphoprotein Reference proteome Repeat Transmembrane Transmembrane helix Transport | MVQASGHRRS | MVQASGHRRSTRGSKMVSWSVIAKIQEILQRKMVREFLAEFMSTYVMMVFGLGSVAHMVLNKKYGSYLGVNLGFGFGVTMGVHVAGRISGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQLMVTGPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALVIGILVVIIGVSLGMNTGYAINPSRDLPPRIFTFIAGWGKQVFSNGENWWWVPVVAPLLGAYLGGIIYLVFIGSTIPREPLKLEDSVAYEDHGITVLPKMGSHEPTISPLTPVSVS... | glycerol transmembrane transport water transport basolateral plasma membrane; cell cortex; cell-cell junction; cytoplasm; cytoplasmic vesicle membrane; lipid droplet; plasma membrane glycerol channel activity urea transmembrane transporter activity water channel activity Homo sapiens 3D-structure Alternative splicing C... |
positive regulation of insulin secretion involved in cellular response to glucose stimulus | cortical endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum-plasma membrane contact site; plasma membrane | insulin binding phosphatidylinositol binding phosphatidylinositol transfer activity | Homo sapiens | 3D-structure Alternative splicing Cell membrane Endoplasmic reticulum Lipid transport Lipid-binding Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport | MDPGWGQRDV | MDPGWGQRDVGWAALLILFAASLLTVFAWLLQYARGLWLARARGDRGPGPALAGEPAGSLRELGVWRSLLRLRATRAGAAEEPGVRGLLASLFAFKSFRENWQRAWVRALNEQACRNGSSIQIAFEEVPQLPPRASISHVTCVDQSEHTMVLRCQLSAEEVRFPVSVTQQSPAAVSMETYHVTLTLPPTQLEVNLEEIPGEGLLISWAFTDRPDLSLTVLPKLQARERGEEQVELSTIEELIKDAIVSTQPAMMVNLRACSAPGGLVPSEKPPMMPQAQPAIPRPNRLFLRQLRASHLGNELEGTEELCCVAELDNPMQQ... | positive regulation of insulin secretion involved in cellular response to glucose stimulus cortical endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum-plasma membrane contact site; plasma membrane insulin binding phosphatidylinositol binding phosphatidylinositol transfer activity Homo sapiens ... |
clathrin coat assembly clathrin-dependent endocytosis positive regulation of T cell activation T cell receptor signaling pathway | clathrin-coated pit; cytoplasm; cytosol; nucleoplasm; plasma membrane | AP-2 adaptor complex binding | Homo sapiens | 3D-structure Alternative splicing Coated pit Coiled coil Disease variant Endocytosis Membrane Phosphoprotein Reference proteome | MSYFGEHFWG | MSYFGEHFWGEKNHGFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTHKKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKKAAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIGQVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGLSRREREPEPPAAVDFLEPDSGTCPEV... | clathrin coat assembly clathrin-dependent endocytosis positive regulation of T cell activation T cell receptor signaling pathway clathrin-coated pit; cytoplasm; cytosol; nucleoplasm; plasma membrane AP-2 adaptor complex binding Homo sapiens 3D-structure Alternative splicing Coated pit Coiled coil Disease variant Endocy... |
microtubule cytoskeleton organization | centrosome; cytoplasm; cytosol; midbody; nucleus | cadherin binding | Homo sapiens | Alternative splicing Cytoplasm Cytoskeleton Nucleus Phosphoprotein Reference proteome | MEADASVDMF | MEADASVDMFSKVLEHQLLQTTKLVEEHLDSEIQKLDQMDEDELERLKEKRLQALRKAQQQKQEWLSKGHGEYREIPSERDFFQEVKESENVVCHFYRDSTFRCKILDRHLAILSKKHLETKFLKLNVEKAPFLCERLHIKVIPTLALLKDGKTQDYVVGFTDLGNTDDFTTETLEWRLGSSDILNYSGNLMEPPFQNQKKFGTNFTKLEKKTIRGKKYDSDSDDD | microtubule cytoskeleton organization centrosome; cytoplasm; cytosol; midbody; nucleus cadherin binding Homo sapiens Alternative splicing Cytoplasm Cytoskeleton Nucleus Phosphoprotein Reference proteome MEADASVDMF MEADASVDMFSKVLEHQLLQTTKLVEEHLDSEIQKLDQMDEDELERLKEKRLQALRKAQQQKQEWLSKGHGEYREIPSERDFFQEVKESENVVCHFYRDSTFRCKI... |
nervous system development | cytosol | filamin binding hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides | Homo sapiens | 3D-structure Cytoplasm Direct protein sequencing Phosphoprotein Reference proteome | MSFQGKKSIP | MSFQGKKSIPRITSDRLLIRGGRIVNDDQSFYADVHVEDGLIKQIGENLIVPGGIKTIDAHGLMVLPGGVDVHTRLQMPVLGMTPADDFCQGTKAALAGGTTMILDHVFPDTGVSLLAAYEQWRERADSAACCDYSLHVDITRWHESIKEELEALVKEKGVNSFLVFMAYKDRCQCSDSQMYEIFSIIRDLGALAQVHAENGDIVEEEQKRLLELGITGPEGHVLSHPEEVEAEAVYRAVTIAKQANCPLYVTKVMSKGAADAIAQAKRRGVVVFGEPITASLGTDGSHYWSKNWAKAAAFVTSPPVNPDPTTADHLTCL... | nervous system development cytosol filamin binding hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides Homo sapiens 3D-structure Cytoplasm Direct protein sequencing Phosphoprotein Reference proteome MSFQGKKSIP MSFQGKKSIPRITSDRLLIRGGRIVNDDQSFYADVHVEDGLIKQIGENLIVPGGIKTIDAHGLMVLPGGVDVHT... |
branching involved in labyrinthine layer morphogenesis cellular response to interleukin-17 cellular response to leukemia inhibitory factor intracellular signal transduction negative regulation of apoptotic process negative regulation of inflammatory response negative regulation of insulin receptor signaling pathway neg... | cytoplasmic side of plasma membrane; cytosol; phosphatidylinositol 3-kinase complex | 1-phosphatidylinositol-3-kinase regulator activity miRNA binding phosphotyrosine residue binding protein kinase inhibitor activity protein tyrosine kinase inhibitor activity | Homo sapiens | Growth regulation Pharmaceutical Phosphoprotein Reference proteome SH2 domain Signal transduction inhibitor Ubl conjugation pathway | MVTHSKFPAA | MVTHSKFPAAGMSRPLDTSLRLKTFSSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCVLKLVHHYMPPPGAPSFPSPPTEPSSEVPEQPSAQPLPGSPPRRAYYIYSGGEKIPLVLSRPLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL | branching involved in labyrinthine layer morphogenesis cellular response to interleukin-17 cellular response to leukemia inhibitory factor intracellular signal transduction negative regulation of apoptotic process negative regulation of inflammatory response negative regulation of insulin receptor signaling pathway neg... |
defense response intracellular signal transduction negative regulation of signal transduction negative regulation of T cell activation phosphatidylinositol phosphate biosynthetic process proteasomal protein catabolic process protein ubiquitination receptor signaling pathway via JAK-STAT regulation of growth | cytoplasm; cytosol; immunological synapse; phosphatidylinositol 3-kinase complex | 1-phosphatidylinositol-3-kinase regulator activity | Homo sapiens | 3D-structure Growth regulation Reference proteome SH2 domain Signal transduction inhibitor Ubl conjugation pathway | MKKISLKTLR | MKKISLKTLRKSFNLNKSKEETDFMVVQQPSLASDFGKDDSLFGSCYGKDMASCDINGEDEKGGKNRSKSESLMGTLKRRLSAKQKSKGKAGTPSGSSADEDTFSSSSAPIVFKDVRAQRPIRSTSLRSHHYSPAPWPLRPTNSEETCIKMEVRVKALVHSSSPSPALNGVRKDFHDLQSETTCQEQANSLKSSASHNGDLHLHLDEHVPVVIGLMPQDYIQYTVPLDEGMYPLEGSRSYCLDSSSPMEVSAVPPQVGGRAFPEDESQVDQDLVVAPEIFVDQSVNGLLIGTTGVMLQSPRAGHDDVPPLSPLLPPMQNN... | defense response intracellular signal transduction negative regulation of signal transduction negative regulation of T cell activation phosphatidylinositol phosphate biosynthetic process proteasomal protein catabolic process protein ubiquitination receptor signaling pathway via JAK-STAT regulation of growth cytoplasm; ... |
flagellated sperm motility glucose metabolic process glycolytic process positive regulation of glycolytic process | cytosol; nucleus | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity NAD binding NADP binding | Homo sapiens | 3D-structure Cytoplasm Glycolysis NAD Oxidoreductase Reference proteome | MSKRDIVLTN | MSKRDIVLTNVTVVQLLRQPCPVTRAPPPPEPKAEVEPQPQPEPTPVREEIKPPPPPLPPHPATPPPKMVSVARELTVGINGFGRIGRLVLRACMEKGVKVVAVNDPFIDPEYMVYMFKYDSTHGRYKGSVEFRNGQLVVDNHEISVYQCKEPKQIPWRAVGSPYVVESTGVYLSIQAASDHISAGAQRVVISAPSPDAPMFVMGVNENDYNPGSMNIVSNASCTTNCLAPLAKVIHERFGIVEGLMTTVHSYTATQKTVDGPSRKAWRDGRGAHQNIIPASTGAAKAVTKVIPELKGKLTGMAFRVPTPDVSVVDLTCR... | flagellated sperm motility glucose metabolic process glycolytic process positive regulation of glycolytic process cytosol; nucleus glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity NAD binding NADP binding Homo sapiens 3D-structure Cytoplasm Glycolysis NAD Oxidoreductase Reference proteome MSKR... |
chaperone-mediated protein folding negative regulation of apoptotic process positive regulation of angiogenesis protein refolding response to heat | cytoplasm; cytosol; extracellular region; mitochondrion; nuclear speck; nucleus | protein folding chaperone protein homodimerization activity protein-folding chaperone binding structural constituent of eye lens unfolded protein binding | Homo sapiens | 3D-structure Chaperone Cytoplasm Direct protein sequencing Nucleus Phosphoprotein Reference proteome Secreted Stress response | MEIPVPVQPS | MEIPVPVQPSWLRRASAPLPGLSAPGRLFDQRFGEGLLEAELAALCPTTLAPYYLRAPSVALPVAQVPTDPGHFSVLLDVKHFSPEEIAVKVVGEHVEVHARHEERPDEHGFVAREFHRRYRLPPGVDPAAVTSALSPEGVLSIQAAPASAQAPPPAAAK | chaperone-mediated protein folding negative regulation of apoptotic process positive regulation of angiogenesis protein refolding response to heat cytoplasm; cytosol; extracellular region; mitochondrion; nuclear speck; nucleus protein folding chaperone protein homodimerization activity protein-folding chaperone binding... |
ascorbate homeostasis | cytoplasmic vesicle membrane; endoplasmic reticulum; endoplasmic reticulum membrane; vesicle | heme binding metal ion binding oxidoreductase activity transmembrane ascorbate ferrireductase activity transmembrane monodehydroascorbate reductase activity | Homo sapiens | Cytoplasmic vesicle Direct protein sequencing Electron transport Endoplasmic reticulum Heme Iron Membrane Metal-binding Reference proteome Translocase Transmembrane Transmembrane helix Transport | MALSAETESH | MALSAETESHIYRALRTASGAAAHLVALGFTIFVAVLARPGSSLFSWHPVLMSLAFSFLMTEALLVFSPESSLLHSLSRKGRARCHWVLQLLALLCALLGLGLVILHKEQLGKAHLVTRHGQAGLLAVLWAGLQCSGGVGLLYPKLLPRWPLAKLKLYHATSGLVGYLLGSASLLLGMCSLWFTASVTGAAWYLAVLCPVLTSLVIMNQVSNAYLYRKRIQP | ascorbate homeostasis cytoplasmic vesicle membrane; endoplasmic reticulum; endoplasmic reticulum membrane; vesicle heme binding metal ion binding oxidoreductase activity transmembrane ascorbate ferrireductase activity transmembrane monodehydroascorbate reductase activity Homo sapiens Cytoplasmic vesicle Direct protein ... |
transport along microtubule vesicle transport along microtubule | cytoplasm; cytoplasmic dynein complex; cytoplasmic ribonucleoprotein granule; cytosol; kinetochore; microtubule; nucleus; perinuclear region of cytoplasm; recycling endosome; spindle pole; vesicle | cytoskeletal motor activity dynein heavy chain binding dynein light chain binding microtubule binding microtubule motor activity spectrin binding | Homo sapiens | Acetylation Alternative splicing Centromere Chromosome Cytoplasm Cytoskeleton Dynein Kinetochore Microtubule Motor protein Phosphoprotein Reference proteome Repeat Transport WD repeat | MSDKSDLKAE | MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALLQSIGISPEPPLVQPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPDGV... | transport along microtubule vesicle transport along microtubule cytoplasm; cytoplasmic dynein complex; cytoplasmic ribonucleoprotein granule; cytosol; kinetochore; microtubule; nucleus; perinuclear region of cytoplasm; recycling endosome; spindle pole; vesicle cytoskeletal motor activity dynein heavy chain binding dyne... |
endoplasmic reticulum to Golgi vesicle-mediated transport intra-Golgi vesicle-mediated transport protein localization to axon protein transport retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum | COPI vesicle coat; cytosol; endoplasmic reticulum membrane; Golgi apparatus; Golgi membrane; nucleoplasm; transport vesicle | structural molecule activity | Homo sapiens | 3D-structure Alternative splicing Cytoplasm Cytoplasmic vesicle Direct protein sequencing ER-Golgi transport Golgi apparatus Membrane Phosphoprotein Protein transport Reference proteome Transport Ubl conjugation | MAPPAPGPAS | MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAYLAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFLLMAASIYLHDQNPDAALRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDATLTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLLQEALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRLVLQYAPSA | endoplasmic reticulum to Golgi vesicle-mediated transport intra-Golgi vesicle-mediated transport protein localization to axon protein transport retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum COPI vesicle coat; cytosol; endoplasmic reticulum membrane; Golgi apparatus; Golgi membrane; nucleoplasm; ... |
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