Biological Process
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Cellular Component
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Molecular Function
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Organism
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Keywords
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Sequence 10
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Sequence
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Combined
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cell differentiation gamete generation
cytosol; membrane; nucleoplasm; nucleus; P granule
ATP binding ATP hydrolysis activity DNA binding RNA binding RNA helicase activity
Homo sapiens
Acetylation Alternative splicing ATP-binding Cytoplasm DNA-binding Helicase Hydrolase Isopeptide bond Methylation Nucleotide-binding Nucleus Phosphoprotein Reference proteome RNA-binding Ubl conjugation
MSHVVVKNDP
MSHVVVKNDPELDQQLANLDLNSEKQSGGASTASKGRYIPPHLRNREASKGFHDKDSSGWSCSKDKDAYSSFGSRDSRGKPGYFSERGSGSRGRFDDRGRSDYDGIGNRERPGFGRFERSGHSRWCDKSVEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVA...
cell differentiation gamete generation cytosol; membrane; nucleoplasm; nucleus; P granule ATP binding ATP hydrolysis activity DNA binding RNA binding RNA helicase activity Homo sapiens Acetylation Alternative splicing ATP-binding Cytoplasm DNA-binding Helicase Hydrolase Isopeptide bond Methylation Nucleotide-binding Nu...
cellular response to amino acid stimulus cytokine-mediated signaling pathway fat cell differentiation intracellular signal transduction macrophage differentiation negative regulation of CD8-positive, alpha-beta T cell differentiation negative regulation of insulin receptor signaling pathway negative regulation of recep...
cytoplasm; cytoplasmic ribonucleoprotein granule; cytoplasmic vesicle; cytosol; nucleoplasm; phosphatidylinositol 3-kinase complex
1-phosphatidylinositol-3-kinase regulator activity insulin-like growth factor receptor binding kinase inhibitor activity protein kinase binding protein kinase inhibitor activity
Homo sapiens
Cytoplasmic vesicle Disease variant Growth regulation Nucleus Reference proteome SH2 domain Signal transduction inhibitor Ubl conjugation pathway
MVAHNQVAAD
MVAHNQVAADNAVSTAAEPRRRPEPSSSSSSSPAAPARPRPCPAVPAPAPGDTHFRTFRSHADYRRITRASALLDACGFYWGPLSVHGAHERLRAEPVGTFLVRDSRQRNCFFALSVKMASGPTSIRVHFQAGRFHLDGSRESFDCLFELLEHYVAAPRRMLGAPLRQRRVRPLQELCRQRIVATVGRENLARIPLNPVLRDYLSSFPFQI
cellular response to amino acid stimulus cytokine-mediated signaling pathway fat cell differentiation intracellular signal transduction macrophage differentiation negative regulation of CD8-positive, alpha-beta T cell differentiation negative regulation of insulin receptor signaling pathway negative regulation of recep...
adult behavior in utero embryonic development negative regulation of transcription by RNA polymerase II positive regulation of gene expression regulation of cell population proliferation regulation of epidermal cell differentiation regulation of transcription by RNA polymerase II
nucleoplasm; nucleus; RNA polymerase II transcription regulator complex
DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific identical protein binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA b...
Homo sapiens
3D-structure Acetylation DNA-binding Isopeptide bond Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation Ubl conjugation
MTTPNKGNKA
MTTPNKGNKALKVKREPGENGTSLTDEELVTMSVRELNQHLRGLSKEEIVQLKQRRRTLKNRGYAASCRVKRVTQKEELEKQKAELQQEVEKLASENASMKLELDALRSKYEALQTFARTVARSPVAPARGPLAAGLGPLVPGKVAATSVITIVKSKTDARS
adult behavior in utero embryonic development negative regulation of transcription by RNA polymerase II positive regulation of gene expression regulation of cell population proliferation regulation of epidermal cell differentiation regulation of transcription by RNA polymerase II nucleoplasm; nucleus; RNA polymerase II...
base-excision repair base-excision repair, AP site formation cellular response to cadmium ion depurination depyrimidination DNA damage response negative regulation of apoptotic process negative regulation of double-strand break repair via single-strand annealing nucleotide-excision repair regulation of DNA-templated tr...
cytosol; mitochondrial matrix; nuclear matrix; nuclear speck; nucleoplasm; nucleus; protein-containing complex
8-oxo-7,8-dihydroguanine DNA N-glycosylase activity class I DNA-(apurinic or apyrimidinic site) endonuclease activity damaged DNA binding endonuclease activity microtubule binding oxidized purine DNA binding oxidized purine nucleobase lesion DNA N-glycosylase activity
Homo sapiens
3D-structure Alternative splicing DNA damage DNA repair Glycosidase Hydrolase Lyase Mitochondrion Multifunctional enzyme Nucleus Reference proteome
MPARALLPRR
MPARALLPRRMGHRTLASTPALWASIPCPRSELRLDLVLPSGQSFRWREQSPAHWSGVLADQVWTLTQTEEQLHCTVYRGDKSQASRPTPDELEAVRKYFQLDVTLAQLYHHWGSVDSHFQEVAQKFQGVRLLRQDPIECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPSLQALAGPEVEAHLRKLGLGYRARYVSASARAILEEQGGLAWLQQLRESSYEEAHKALCILPGVGTKVADCICLMALDKPQAVPVDVHMWHIAQRDYSWHPTTSQAKGPSPQTNKELGNFFRSLWGPYAGWAQAVLFS...
base-excision repair base-excision repair, AP site formation cellular response to cadmium ion depurination depyrimidination DNA damage response negative regulation of apoptotic process negative regulation of double-strand break repair via single-strand annealing nucleotide-excision repair regulation of DNA-templated tr...
bone mineralization calcitriol biosynthetic process from calciol calcium ion homeostasis calcium ion transport decidualization G1 to G0 transition negative regulation of calcidiol 1-monooxygenase activity negative regulation of cell growth negative regulation of cell population proliferation positive regulation of kera...
cytoplasm; mitochondrial outer membrane; mitochondrion
calcidiol 1-monooxygenase activity heme binding iron ion binding secalciferol 1-monooxygenase activity
Homo sapiens
Disease variant Heme Iron Lipid metabolism Membrane Metal-binding Mitochondrion Monooxygenase Oxidoreductase Reference proteome Transit peptide
MTQTLKYASR
MTQTLKYASRVFHRVRWAPELGASLGYREYHSARRSLADIPGPSTPSFLAELFCKGGLSRLHELQVQGAAHFGPVWLASFGTVRTVYVAAPALVEELLRQEGPRPERCSFSPWTEHRRCRQRACGLLTAEGEEWQRLRSLLAPLLLRPQAAARYAGTLNNVVCDLVRRLRRQRGRGTGPPALVRDVAGEFYKFGLEGIAAVLLGSRLGCLEAQVPPDTETFIRAVGSVFVSTLLTMAMPHWLRHLVPGPWGRLCRDWDQMFAFAQRHVERREAEAAMRNGGQPEKDLESGAHLTHFLFREELPAQSILGNVTELLLAGVD...
bone mineralization calcitriol biosynthetic process from calciol calcium ion homeostasis calcium ion transport decidualization G1 to G0 transition negative regulation of calcidiol 1-monooxygenase activity negative regulation of cell growth negative regulation of cell population proliferation positive regulation of kera...
G protein-coupled receptor signaling pathway
plasma membrane
G protein-coupled receptor activity
Homo sapiens
Cell membrane G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Transducer Transmembrane Transmembrane helix
MDTGPDQSYF
MDTGPDQSYFSGNHWFVFSVYLLTFLVGLPLNLLALVVFVGKLRCRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANGMHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAGLVSVACWLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAILLPVRLEMAVVLFVVPLIITSYCYSRLVWILGRGGSHRRQRRVAGLVAATLLNFLVCFGPYNVSHVVGYICGESPVWRIYVTLLSTLNSCVDPFVYYFSSSGFQADFHELLRRLCGLWGQWQQESSMELKEQKGGEEQRA...
G protein-coupled receptor signaling pathway plasma membrane G protein-coupled receptor activity Homo sapiens Cell membrane G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Transducer Transmembrane Transmembrane helix MDTGPDQSYF MDTGPDQSYFSGNHWFVFSVYLLTFLVGLPLNLLALVVFVGKLRCRPVAVDVLLLNLTASDLL...
antigen processing and presentation of endogenous peptide antigen via MHC class I MHC class Ib protein complex assembly peptide antigen assembly with MHC class I protein complex peptide antigen stabilization protein-containing complex assembly regulation of gene expression regulation of protein complex stability retrog...
endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment membrane; Golgi membrane; lumenal side of endoplasmic reticulum membrane; MHC class I peptide loading complex; phagocytic vesicle membrane; Tapasin-ERp57 complex
MHC class I protein binding MHC class I protein complex binding molecular adaptor activity peptide antigen binding protein folding chaperone TAP complex binding TAP1 binding TAP2 binding unfolded protein binding
Homo sapiens
3D-structure Alternative splicing Direct protein sequencing Disulfide bond Endoplasmic reticulum Glycoprotein Immunoglobulin domain Membrane Reference proteome Signal Transmembrane Transmembrane helix
MKSLSLLLAV
MKSLSLLLAVALGLATAVSAGPAVIECWFVEDASGKGLAKRPGALLLRQGPGEPPPRPDLDPELYLSVHDPAGALQAAFRRYPRGAPAPHCEMSRFVPLPASAKWASGLTPAQNCPRALDGAWLMVSISSPVLSLSSLLRPQPEPQQEPVLITMATVVLTVLTHTPAPRVRLGQDALLDLSFAYMPPTSEAASSLAPGPPPFGLEWRRQHLGKGHLLLAATPGLNGQMPAAQEGAVAFAAWDDDEPWGPWTGNGTFWLPTVQPFQEGTYLATIHLPYLQGQVTLELAVYKPPKVSLMPATLARAAPGEAPPELLCLVSHF...
antigen processing and presentation of endogenous peptide antigen via MHC class I MHC class Ib protein complex assembly peptide antigen assembly with MHC class I protein complex peptide antigen stabilization protein-containing complex assembly regulation of gene expression regulation of protein complex stability retrog...
regulation of transcription by RNA polymerase II
nucleus
DNA-binding transcription factor activity, RNA polymerase II-specific metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding
Homo sapiens
Alternative splicing DNA-binding Isopeptide bond Metal-binding Nucleus Reference proteome Repeat Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger
MNTNSKEVLS
MNTNSKEVLSLGVQVPEAWEELLTMKVEAKSHLQWQESRLKRSNPLAREIFRRHFRQLCYQETPGPREALTRLQELCYQWLRPHVSTKEQILDLLVLEQFLSILPKELQGWVREHCPESGEEAVILLEDLERELDEPQHEMVAHRHRQEVLCKEMVPLAEQTPLTLQSQPKEPQLTCDSAQKCHSIGETDEVTKTEDRELVLRKDCPKIVEPHGKMFNEQTWEVSQQDPSHGEVGEHKDRIERQWGNLLGEGQHKCDECGKSFTQSSGLIRHQRIHTGERPYECNECGKAFSRSSGLFNHRGIHNIQKRYHCKECGKVFS...
regulation of transcription by RNA polymerase II nucleus DNA-binding transcription factor activity, RNA polymerase II-specific metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding Homo sapiens Alternative splicing DNA-binding Isopeptide bo...
adaptation of rhodopsin mediated signaling cell adhesion eye development protein homooligomerization retina layer formation visual perception
external side of plasma membrane; extracellular space; neuron to neuron synapse; photoreceptor inner segment
phosphatidylinositol-3,4-bisphosphate binding phosphatidylserine binding
Homo sapiens
3D-structure Cell adhesion Cell membrane Disease variant Disulfide bond Lipid-binding Membrane Reference proteome Secreted Sensory transduction Signal Vision
MSRKIEGFLL
MSRKIEGFLLLLLFGYEATLGLSSTEDEGEDPWYQKACKCDCQGGPNALWSAGATSLDCIPECPYHKPLGFESGEVTPDQITCSNPEQYVGWYSSWTANKARLNSQGFGCAWLSKFQDSSQWLQIDLKEIKVISGILTQGRCDIDEWMTKYSVQYRTDERLNWIYYKDQTGNNRVFYGNSDRTSTVQNLLRPPIISRFIRLIPLGWHVRIAIRMELLECVSKCA
adaptation of rhodopsin mediated signaling cell adhesion eye development protein homooligomerization retina layer formation visual perception external side of plasma membrane; extracellular space; neuron to neuron synapse; photoreceptor inner segment phosphatidylinositol-3,4-bisphosphate binding phosphatidylserine bind...
epithelial cell proliferation fatty acid transport negative regulation of cell population proliferation nervous system development
cytosol; nucleus
fatty acid binding lipid binding
Homo sapiens
3D-structure Acetylation Alternative splicing Cytoplasm Direct protein sequencing Lipid-binding Reference proteome Transport
MVEAFCATWK
MVEAFCATWKLTNSQNFDEYMKALGVGFATRQVGNVTKPTVIISQEGDKVVIRTLSTFKNTEISFQLGEEFDETTADDRNCKSVVSLDGDKLVHIQKWDGKETNFVREIKDGKMVMTLTFGDVVAVRHYEKA
epithelial cell proliferation fatty acid transport negative regulation of cell population proliferation nervous system development cytosol; nucleus fatty acid binding lipid binding Homo sapiens 3D-structure Acetylation Alternative splicing Cytoplasm Direct protein sequencing Lipid-binding Reference proteome Transport M...
DNA repair mRNA splicing, via spliceosome negative regulation of chemokine-mediated signaling pathway protein ubiquitination snoRNA splicing
nuclear speck; nucleoplasm; nucleus; U2-type precatalytic spliceosome; U2-type spliceosomal complex
metal ion binding ubiquitin protein ligase activity
Homo sapiens
3D-structure Acetylation DNA damage DNA repair Metal-binding mRNA processing mRNA splicing Nucleus Phosphoprotein Reference proteome Spliceosome Transferase Ubl conjugation pathway Zinc Zinc-finger
MAEQLSPGKA
MAEQLSPGKAVDQVCTFLFKKPGRKGAAGRRKRPACDPEPGESGSSSDEGCTVVRPEKKRVTHNPMIQKTRDSGKQKAAYGDLSSEEEEENEPESLGVVYKSTRSAKPVGPEDMGATAVYELDTEKERDAQAIFERSQKIQEELRGKEDDKIYRGINNYQKYMKPKDTSMGNASSGMVRKGPIRAPEHLRATVRWDYQPDICKDYKETGFCGFGDSCKFLHDRSDYKHGWQIERELDEGRYGVYEDENYEVGSDDEEIPFKCFICRQSFQNPVVTKCRHYFCESCALQHFRTTPRCYVCDQQTNGVFNPAKELIAKLEKH...
DNA repair mRNA splicing, via spliceosome negative regulation of chemokine-mediated signaling pathway protein ubiquitination snoRNA splicing nuclear speck; nucleoplasm; nucleus; U2-type precatalytic spliceosome; U2-type spliceosomal complex metal ion binding ubiquitin protein ligase activity Homo sapiens 3D-structure A...
calcium ion transmembrane transport muscle contraction response to ATP signal transduction
cell junction; cytoplasm; dendritic spine; glutamatergic synapse; neuronal cell body; parallel fiber to Purkinje cell synapse; plasma membrane; postsynaptic specialization membrane; receptor complex
ATP binding channel activity extracellularly ATP-gated monoatomic cation channel activity protein-containing complex binding purinergic nucleotide receptor activity transmembrane signaling receptor activity
Homo sapiens
Alternative splicing Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Phosphoprotein Receptor Reference proteome Transmembrane Transmembrane helix Transport
MCPQLAGAGS
MCPQLAGAGSMGSPGATTGWGLLDYKTEKYVMTRNWRVGALQRLLQFGIVVYVVGWALLAKKGYQERDLEPQFSIITKLKGVSVTQIKELGNRLWDVADFVKPPQGENVFFLVTNFLVTPAQVQGRCPEHPSVPLANCWVDEDCPEGEGGTHSHGVKTGQCVVFNGTHRTCEIWSWCPVESGVVPSRPLLAQAQNFTLFIKNTVTFSKFNFSKSNALETWDPTYFKHCRYEPQFSPYCPVFRIGDLVAKAGGTFEDLALLGGSVGIRVHWDCDLDTGDSGCWPHYSFQLQEKSYNFRTATHWWEQPGVEARTLLKLYGIR...
calcium ion transmembrane transport muscle contraction response to ATP signal transduction cell junction; cytoplasm; dendritic spine; glutamatergic synapse; neuronal cell body; parallel fiber to Purkinje cell synapse; plasma membrane; postsynaptic specialization membrane; receptor complex ATP binding channel activity e...
actin cytoskeleton organization bicellular tight junction assembly calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules cell adhesion cell junction maintenance epithelial cell morphogenesis establishment of endothelial blood-brain barrier maintenance of blood-brain barrier negative regulat...
apical junction complex; apicolateral plasma membrane; bicellular tight junction; cell-cell junction; lateral plasma membrane; membrane; plasma membrane; protein-containing complex; tight junction
identical protein binding structural molecule activity transmembrane signaling receptor activity
Homo sapiens
Cell junction Cell membrane Membrane Phosphoprotein Reference proteome Tight junction Transmembrane Transmembrane helix Williams-Beuren syndrome
MSMGLEITGT
MSMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQMQCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVAGVLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLCCSCPPREKKYTATKVVYSAPRSTGPGASLGTGYDRKDYV
actin cytoskeleton organization bicellular tight junction assembly calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules cell adhesion cell junction maintenance epithelial cell morphogenesis establishment of endothelial blood-brain barrier maintenance of blood-brain barrier negative regulat...
cell surface pattern recognition receptor signaling pathway cellular response to fatty acid fat cell differentiation G protein-coupled receptor signaling pathway glucose homeostasis leukocyte chemotaxis involved in inflammatory response ligand-gated ion channel signaling pathway lipid storage mucosal immune response ne...
cell projection; plasma membrane
G protein-coupled receptor activity lipid binding
Homo sapiens
Cell membrane G-protein coupled receptor Glycoprotein Immunity Inflammatory response Lipid-binding Membrane Receptor Reference proteome Transducer Transmembrane Transmembrane helix
MLPDWKSSLI
MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPVHILLLSLTLADLLLLLLLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGISIERYLGVAFPVQYKLSRRPLYGVIAALVAWVMSFGHCTIVIIVQYLNTTEQVRSGNEITCYENFTDNQLDVVLPVRLELCLVLFFIPMAVTIFCYWRFVWIMLSQPLVGAQRRRRAVGLAVVTLLNFLVCFGPYNVSHLVGYHQRKSPWWRSIAVVFSSLNASLDPLLFYFSSSVVRRAFGRGLQVLRNQGSSLLGRRGKDTAEGTNEDRGVGQGE...
cell surface pattern recognition receptor signaling pathway cellular response to fatty acid fat cell differentiation G protein-coupled receptor signaling pathway glucose homeostasis leukocyte chemotaxis involved in inflammatory response ligand-gated ion channel signaling pathway lipid storage mucosal immune response ne...
inflammatory response innate immune response negative regulation of cytokine production involved in inflammatory response negative regulation of inflammatory response negative regulation of interleukin-1 beta production negative regulation of interleukin-12 production negative regulation of macrophage inflammatory prot...
autophagosome; canonical inflammasome complex; cytoplasm; cytoplasmic vesicle; cytosol; lamellipodium; microtubule; microtubule associated complex; nucleoplasm; nucleus; ruffle
actin binding identical protein binding ubiquitin protein ligase activity zinc ion binding
Homo sapiens
3D-structure Actin-binding Alternative splicing Amyloidosis Cell projection Coiled coil Cytoplasm Cytoplasmic vesicle Cytoskeleton Disease variant Immunity Inflammatory response Innate immunity Metal-binding Microtubule Nucleus Phosphoprotein Reference proteome Zinc Zinc-finger
MAKTPSDHLL
MAKTPSDHLLSTLEELVPYDFEKFKFKLQNTSVQKEHSRIPRSQIQRARPVKMATLLVTYYGEEYAVQLTLQVLRAINQRLLAEELHRAAIQEYSTQENGTDDSAASSSLGENKPRSLKTPDHPEGNEGNGPRPYGGGAASLRCSQPEAGRGLSRKPLSKRREKASEGLDAQGKPRTRSPALPGGRSPGPCRALEGGQAEVRLRRNASSAGRLQGLAGGAPGQKECRPFEVYLPSGKMRPRSLEVTISTGEKAPANPEILLTLEEKTAANLDSATEPRARPTPDGGASADLKEGPGNPEHSVTGRPPDTAASPRCHAQEG...
inflammatory response innate immune response negative regulation of cytokine production involved in inflammatory response negative regulation of inflammatory response negative regulation of interleukin-1 beta production negative regulation of interleukin-12 production negative regulation of macrophage inflammatory prot...
calcium ion transport cell volume homeostasis defense response establishment of localization in cell immune system process phospholipid translocation positive regulation of potassium ion transmembrane transport positive regulation of protein secretion positive regulation of T cell receptor signaling pathway potassium i...
cytosol; neuron projection; neuronal cell body; plasma membrane; vesicle; voltage-gated potassium channel complex
calcium-activated potassium channel activity calmodulin binding Intermediate conductance calcium-activated potassium channel activity potassium channel activity protein phosphatase binding small conductance calcium-activated potassium channel activity
Homo sapiens
3D-structure Calmodulin-binding Cell membrane Disease variant Hereditary hemolytic anemia Immunity Ion channel Ion transport Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport
MGGDLVLGLG
MGGDLVLGLGALRRRKRLLEQEKSLAGWALVLAGTGIGLMVLHAEMLWFGGCSWALYLFLVKCTISISTFLLLCLIVAFHAKEVQLFMTDNGLRDWRVALTGRQAAQIVLELVVCGLHPAPVRGPPCVQDLGAPLTSPQPWPGFLGQGEALLSLAMLLRLYLVPRAVLLRSGVLLNASYRSIGALNQVRFRHWFVAKLYMNTHPGRLLLGLTLGLWLTTAWVLSVAERQAVNATGHLSDTLWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVHNFMMDIQYTKEMKESAARVLQ...
calcium ion transport cell volume homeostasis defense response establishment of localization in cell immune system process phospholipid translocation positive regulation of potassium ion transmembrane transport positive regulation of protein secretion positive regulation of T cell receptor signaling pathway potassium i...
fructose 6-phosphate metabolic process glycolytic process
glycosome
6-phosphofructokinase activity ATP binding metal ion binding phosphate ion binding
Trypanosoma brucei brucei
3D-structure Allosteric enzyme ATP-binding Direct protein sequencing Glycolysis Glycosome Kinase Magnesium Metal-binding Nucleotide-binding Peroxisome Transferase
MAVESRSRVT
MAVESRSRVTSKLVKAHRAMLNSVTQEDLKVDRLPGADYPNPSKKYSSRTEFRDKTDYIMYNPRPRDEPSSENPVSVSPLLCELAAARSRIHFNPTETTIGIVTCGGICPGLNDVIRSITLTGINVYNVKRVIGFRFGYWGLSKKGSQTAIELHRGRVTNIHHYGGTILGSSRGPQDPKEMVDTLERLGVNILFTVGGDGTQRGALVISQEAKRRGVDISVFGVPKTIDNDLSFSHRTFGFQTAVEKAVQAIRAAYAEAVSANYGVGVVKLMGRDSGFIAAQAAVASAQANICLVPENPISEQEVMSLLERRFCHSRSCV...
fructose 6-phosphate metabolic process glycolytic process glycosome 6-phosphofructokinase activity ATP binding metal ion binding phosphate ion binding Trypanosoma brucei brucei3D-structure Allosteric enzyme ATP-binding Direct protein sequencing Glycolysis Glycosome Kinase Magnesium Metal-binding Nucleotide-binding Pero...
phosphorylation
cytoplasmic vesicle; extracellular region; host cell surface; microneme
ATP binding metal ion binding protein serine kinase activity protein serine/threonine kinase activity
Plasmodium falciparum
ATP-binding Cytoplasm Cytoplasmic vesicle Kinase Magnesium Metal-binding Nucleotide-binding Secreted Serine/threonine-protein kinase Transferase
MEIRVANKYA
MEIRVANKYALGKKLGSGSFGDIYVAKDIVTMEEFAVKLESTRSKHPQLLYESKLYKILGGGIGVPKVYWYGIEGDFTIMVLDLLGPSLEDLFTLCNRKFSLKTVRMTADQMLNRIEYVHSKNFIHRDIKPDNFLIGRGKKVTLIHIIDFGLAKKYRDSRSHTSYPYKEGKNLTGTARYASINTHLGIEQSRRDDIEALGYVLMYFLRGSLPWQGLKAISKKDKYDKIMEKKISTSVEVLCRNASFEFVTYLNYCRSLRFEDRPDYTYLRRLLKDLFIREGFTYDFLFDWTCVYASEKDKKKMLENKNRFDQTADQEGRD...
phosphorylation cytoplasmic vesicle; extracellular region; host cell surface; microneme ATP binding metal ion binding protein serine kinase activity protein serine/threonine kinase activity Plasmodium falciparum ATP-binding Cytoplasm Cytoplasmic vesicle Kinase Magnesium Metal-binding Nucleotide-binding Secreted Serine/...
anatomical structure morphogenesis cell differentiation G protein-coupled receptor signaling pathway
cytosol; membrane; plasma membrane; ruffle
G-protein beta/gamma-subunit complex binding GTP binding GTPase activity magnesium ion binding manganese ion binding myosin phosphatase activity protein serine/threonine phosphatase activity
Dictyostelium discoideum
Cell membrane Coiled coil Cytoplasm GTP-binding Hydrolase Magnesium Manganese Membrane Metal-binding Nucleotide-binding Protein phosphatase Reference proteome Transducer
MKKMLFMNKK
MKKMLFMNKKEKKEEQSPAHSSLAQQHQLAQQQYQLQQQQLQLQYQQHQQQLQLAQQQKQNEQNLAQLSTSTSSNSSVNNTTNTNTNTTNSSSISSNNNNNNNTAVPILKAHDFCGTIMILGHTESGKTTLQRQLEFIYGVTDPTDAKHYQRLIYGNTLATLIRFIENSERLNITLSPDNLARVKRIQSQPVELARNRLPRFPLKLGWDCKCIWEDKVIQSVYNHSKICSEIRTPGRPKYYMDRMFKVFDPSYTPTEMDIISAYDQKDTIQSSAIIHKRFKVDLFGCSGKQSSPKNWVGLHQNYKPNYIFYVVALKDYFS...
anatomical structure morphogenesis cell differentiation G protein-coupled receptor signaling pathway cytosol; membrane; plasma membrane; ruffle G-protein beta/gamma-subunit complex binding GTP binding GTPase activity magnesium ion binding manganese ion binding myosin phosphatase activity protein serine/threonine phosph...
cell redox homeostasis response to oxidative stress
apicoplast; cytoplasm
flavin adenine dinucleotide binding glutathione-disulfide reductase (NADP) activity
Plasmodium falciparum
Alternative initiation Apicoplast Cytoplasm Disulfide bond FAD Flavoprotein NADP Oxidoreductase Plastid Redox-active center Reference proteome Transit peptide
MYKHRYFHFF
MYKHRYFHFFFFFFFFLVSTKIIRSFTFLNNNTNLSNPVYFKKKANMVYDLIVIGGGSGGMAAARRAARHNAKVALVEKSRLGGTCVNVGCVPKKIMFNAASVHDILENSRHYGFDTKFSFNLPLLVERRDKYIQRLNNIYRQNLSKDKVDLYEGTASFLSENRILIKGTKDNNNKDNGPLNEEILEGRNILIAVGNKPVFPPVKGIENTISSDEFFNIKESKKIGIVGSGYIAVELINVIKRLGIDSYIFARGNRILRKFDESVINVLENDMKKNNINIVTFADVVEIKKVSDKNLSIHLSDGRIYEHFDHVIYCVGRS...
cell redox homeostasis response to oxidative stress apicoplast; cytoplasm flavin adenine dinucleotide binding glutathione-disulfide reductase (NADP) activity Plasmodium falciparum Alternative initiation Apicoplast Cytoplasm Disulfide bond FAD Flavoprotein NADP Oxidoreductase Plastid Redox-active center Reference proteo...
chromatin remodeling epigenetic regulation of gene expression response to mercury ion
nucleolar chromatin; nucleosome; nucleus
DNA binding protein heterodimerization activity structural constituent of chromatin
Dictyostelium discoideum
Acetylation Chromosome Direct protein sequencing DNA-binding Methylation Nucleosome core Nucleus Phosphoprotein Reference proteome
MARTKQTARK
MARTKQTARKSTGAKVPRKHIGSKQAHKQTPVSSSSGGVKKVHRFRPGTVALREIRKYQKSTDLLIRKLPFQRLVREIAQEFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIHLARRIRGERS
chromatin remodeling epigenetic regulation of gene expression response to mercury ion nucleolar chromatin; nucleosome; nucleus DNA binding protein heterodimerization activity structural constituent of chromatin Dictyostelium discoideum Acetylation Chromosome Direct protein sequencing DNA-binding Methylation Nucleosome ...
deoxyribonucleotide biosynthetic process DNA replication
nucleoplasm; ribonucleoside-diphosphate reductase complex
ATP binding ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
Trypanosoma brucei brucei
Allosteric enzyme ATP-binding Deoxyribonucleotide synthesis Disulfide bond Nucleotide-binding Oxidoreductase
MLETVKLVTK
MLETVKLVTKRDGSVEPYDEKVVRSRIVNLMSGIDSYYVDVDDLVRVVGEGVREGMSTSMLDELLAETAAYCVTKHPDYGLLAGRLAVTALHKTTTESVLDSFRVLHEHVSQATKRHAPLISEELWDIANKHSAALQQIINYERDFDFEYFGYKTLERSYLLRVHKGRGVMEVVERPQQMFLRVALGIHGEDLERVKETYDYMSQGFFTHATPTLFNAGTPFPQMSSCFLVAMREDSIDGIYDTLKQCAIISKSAGGIGIHMHNIRAAGSYIAGTNGTSNGLVPMLRVWNNTARYVDQGGGKRKGAFAIYLEPWHADIFG...
deoxyribonucleotide biosynthetic process DNA replication nucleoplasm; ribonucleoside-diphosphate reductase complex ATP binding ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor Trypanosoma brucei bruceiAllosteric enzyme ATP-binding Deoxyribonucleotide synthesis Disulfide bond Nucleotide-b...
appendage development brain development cellular response to hypoxia cellular response to insulin stimulus central nervous system development glial cell migration imaginal disc-derived leg joint morphogenesis insulin receptor signaling pathway negative regulation of transcription by RNA polymerase II oogenesis positive...
aryl hydrocarbon receptor complex; cytoplasm; nucleus; protein-containing complex; RNA polymerase II transcription regulator complex
DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific myosin binding protein heterodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-speci...
Drosophila melanogaster
Activator DNA-binding Nucleus Reference proteome Repeat Transcription Transcription regulation
MDEANIQDKE
MDEANIQDKERFASRENHCEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVAHMKALRGTGNTSSDGTYKPSFLTDQELKHLILEAADGFLFVVSCDSGRVIYVSDSVTPVLNYTQSDWYGTSLYEHIHPDDREKIREQLSTQESQNAGRILDLKSGTVKKEGHQSSMRLSMGARRGFICRMRVGNVNPESMVSGHLNRLKQRNSLGPSRDGTNYAVVHCTGYIKNWPPTDMFPNMHMERDVDDMSSHCCLVAIGRLQVTSTAANDMSGSNNQSEFITRHAMDGKFTFVDQRVLNILGYTPTELLGKICYD...
appendage development brain development cellular response to hypoxia cellular response to insulin stimulus central nervous system development glial cell migration imaginal disc-derived leg joint morphogenesis insulin receptor signaling pathway negative regulation of transcription by RNA polymerase II oogenesis positive...
calcium-mediated signaling cell differentiation chemical synaptic transmission exocytosis insulin receptor signaling pathway intracellular protein transport locomotion neurotransmitter secretion positive regulation of anterior/posterior axon guidance regulation of multicellular organism growth synaptic transmission, ch...
axon; basolateral plasma membrane; dendrite; endomembrane system; membrane; neuronal cell body; perikaryon; plasma membrane; presynaptic active zone membrane; SNARE complex; synaptic vesicle
protein-folding chaperone binding SNAP receptor activity SNARE binding structural constituent of cuticle
Caenorhabditis elegans
Alternative splicing Cell membrane Cell projection Coiled coil Cuticle Developmental protein Differentiation Membrane Neurogenesis Neurotransmitter transport Reference proteome Transmembrane Transmembrane helix Transport
MTKDRLSALK
MTKDRLSALKAAQSEDEQDDDMHMDTGNAQYMEEFFEQVEEIRGSVDIIANNVEEVKKKHSAILSNPVNDQKTKEELDELMAVIKRAANKVRGKLKLIENAIDHDEQGAGNADLRIRKTQHSTLSRRFVEVMTDYNKTQTDYRERCKGRIQRQLDIAGKQVGDEDLEEMIESGNPGVFTQGIITDTQQAKQTLADIEARHNDIMKLESSIRELHDMFMDMAMLVESQGEMVDRIEYNVEHAKEFVDRAVADTKKAVQYQSKARRKKICILVTGVILITGLIIFILFYAKVL
calcium-mediated signaling cell differentiation chemical synaptic transmission exocytosis insulin receptor signaling pathway intracellular protein transport locomotion neurotransmitter secretion positive regulation of anterior/posterior axon guidance regulation of multicellular organism growth synaptic transmission, ch...
apoptotic process compound eye photoreceptor cell differentiation eye development muscle cell cellular homeostasis muscle organ development regulation of alternative mRNA splicing, via spliceosome regulation of female receptivity regulation of gene expression regulation of RNA splicing response to stimulus rhabdomere d...
cytoplasm; H zone; nucleus; perinuclear region of cytoplasm; Z disc
metal ion binding nucleic acid binding RNA binding
Drosophila melanogaster
Alternative splicing Developmental protein Metal-binding Nucleus Reference proteome Repeat Sensory transduction Vision Zinc Zinc-finger
MANVVNMNSL
MANVVNMNSLLNGKDSRWLQLEVCREFQRNKCSRQDTECKFAHPPANVEVQNGKVTACYDSIKGRCNRDKPPCKYFHPPQHLKDQLLINGRNHLALKNALMQQMGIAPGQPVISGQVPAVATNPYLTGIPANSYSPYYTTGHLVPALLGPDPVTSQLGPVVPQTVQVAQQKIPRSDRLETSPLAAHHHQQQQQLQHQLNNINNNNNHSTAGAAATSTTATTTTNNAAAAAAAAAAAAAAAVMGHHTLEVGKKRAADTTDMFPLVFFCSFPSPCVFAFLNCSIFGFLRLWFSLFNLRH
apoptotic process compound eye photoreceptor cell differentiation eye development muscle cell cellular homeostasis muscle organ development regulation of alternative mRNA splicing, via spliceosome regulation of female receptivity regulation of gene expression regulation of RNA splicing response to stimulus rhabdomere d...
chromatin organization chromatin remodeling negative regulation of transcription by RNA polymerase II nucleosome organization
chromatin; euchromatin; nucleus; NuRD complex
ATP binding ATP hydrolysis activity ATP-dependent chromatin remodeler activity chromatin binding DNA binding helicase activity histone binding metal ion binding
Drosophila melanogaster
Activator ATP-binding Chromosome DNA-binding Helicase Hydrolase Metal-binding Nucleotide-binding Nucleus Reference proteome Repeat Transcription Transcription regulation Zinc Zinc-finger
MSSKRGADPD
MSSKRGADPDWKTPGKASKDKRPKTNAKKQKFRDEEYCKVCSDGGDLLCCDSCPSVYHRTCLSPPLKSIPKGDWICPRCIPLPGKAEKILSWRWALDRSVELRTSKGEKRREYFIKWHGMSYWHCEWIPEGQMLLHHASMVASFQRRSDMEEPSLEELDDQDGNLHERFYRYGIKPEWLLVQRVINHSEEPNGGTMYLVKWRELSYNDSSWERESDSIPGLNQAIALYKKLRSSNKGRQRDRPAPTIDLNKKYEDQPVFLKEAGLKLHPFQIEGVSWLRYSWGQGIPTILADEMGLGKTIQTVVFLYSLFKEGHCRGPFL...
chromatin organization chromatin remodeling negative regulation of transcription by RNA polymerase II nucleosome organization chromatin; euchromatin; nucleus; NuRD complex ATP binding ATP hydrolysis activity ATP-dependent chromatin remodeler activity chromatin binding DNA binding helicase activity histone binding metal...
cellular response to glyoxal cellular response to methylglyoxal glycolate biosynthetic process glyoxal metabolic process lactate biosynthetic process methylglyoxal metabolic process negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway response to oxidative stress
cytoplasm; mitochondrion; nucleus
glyoxalase III activity
Caenorhabditis elegans
Cytoplasm Lyase Reference proteome
MAAQKSALIL
MAAQKSALILLPPEDAEEIEVIVTGDVLVRGGLQVLYAGSSTEPVKCAKGARIVPDVALKDVKNKTFDIIIIPGGPGCSKLAECPVIGELLKTQVKSGGLIGAICAGPTVLLAHGIVAERVTCHYTVKDKMTEGGYKYLDDNVVISDRVITSKGPGTAFEFALKIVETLEGPEKTNSLLKPLCLAK
cellular response to glyoxal cellular response to methylglyoxal glycolate biosynthetic process glyoxal metabolic process lactate biosynthetic process methylglyoxal metabolic process negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway response to oxidative stress cytoplasm; mitochondrio...
determination of adult lifespan protein maturation by protein folding reproduction response to heat
cytoplasm; protein folding chaperone complex
ATPase inhibitor activity Hsp70 protein binding Hsp90 protein binding
Caenorhabditis elegans
3D-structure Cytoplasm Developmental protein Reference proteome Repeat Stress response TPR repeat
MTDAAIAEKD
MTDAAIAEKDLGNAAYKQKDFEKAHVHYDKAIELDPSNITFYNNKAAVYFEEKKFAECVQFCEKAVEVGRETRADYKLIAKAMSRAGNAFQKQNDLSLAVQWFHRSLSEFRDPELVKKVKELEKQLKAAERLAYINPELAQEEKNKGNEYFKKGDYPTAMRHYNEAVKRDPENAILYSNRAACLTKLMEFQRALDDCDTCIRLDSKFIKGYIRKAACLVAMREWSKAQRAYEDALQVDPSNEEAREGVRNCLRSNDEDPEKAKERSLADPEVQEILRDPGMRMILEQMSNDPGAVREHLKNPEIFQKLMKLRDAGVIQMR
determination of adult lifespan protein maturation by protein folding reproduction response to heat cytoplasm; protein folding chaperone complex ATPase inhibitor activity Hsp70 protein binding Hsp90 protein binding Caenorhabditis elegans3D-structure Cytoplasm Developmental protein Reference proteome Repeat Stress respo...
ATP metabolic process cell cycle cell division positive regulation of mitotic cell cycle
nucleus
ATP binding ATP hydrolysis activity hydrolase activity magnesium ion binding microtubule binding microtubule severing ATPase activity
Caenorhabditis elegans
3D-structure ATP-binding Cell cycle Cell division Hydrolase Magnesium Metal-binding Mitosis Nucleotide-binding Nucleus Reference proteome
MYSPKRVKLN
MYSPKRVKLNVTSGMRKRPETGENNDDLYPPTALARNGISPYFIGKPRRKIVVETPSDSAQQQPPFKSRSQQNGLDDELDGIIIDEDEDRTVDVSFSQKQDTRKLKSRPFLGEKSSFKLGEIPKPKEEKRREEPFTMRGFDFGSDDKVTKIRDKICDIVDPTNARRTDPNFIRQMHENTLKGIEVASNPHFKKTRAPTKNRAAIQNTLGTLYPSFTTAAGQDPQNSKFQVPLDRQSSSQSIGSLAGIPPARRAPDIPKRCSNPLIRKAMGMDTEGGGKDEKMSGLRAEPTLKHFDENIISLIESEIMSVNNEIGWADVAG...
ATP metabolic process cell cycle cell division positive regulation of mitotic cell cycle nucleus ATP binding ATP hydrolysis activity hydrolase activity magnesium ion binding microtubule binding microtubule severing ATPase activity Caenorhabditis elegans3D-structure ATP-binding Cell cycle Cell division Hydrolase Magnesi...
apoptotic cell clearance cell migration embryo development ending in birth or egg hatching establishment of meiotic spindle orientation negative regulation of gene expression positive chemotaxis regulation of apoptotic process regulation of cell cycle regulation of protein localization
calcineurin complex; cell periphery; centrosome; mitotic spindle; nuclear membrane
calcium ion binding enzyme regulator activity
Caenorhabditis elegans
3D-structure Acetylation Calcium Metal-binding Methylation Reference proteome Repeat
MADQLTEEQI
MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMTTK
apoptotic cell clearance cell migration embryo development ending in birth or egg hatching establishment of meiotic spindle orientation negative regulation of gene expression positive chemotaxis regulation of apoptotic process regulation of cell cycle regulation of protein localization calcineurin complex; cell periphe...
glycosylation N-glycan processing protein galactosylation
cytoplasm; Golgi cisterna membrane; intracellular organelle
beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity glycosyltransferase activity metal ion binding UDP-galactosyltransferase activity
Caenorhabditis elegans
Glycoprotein Glycosyltransferase Golgi apparatus Manganese Membrane Metal-binding Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix
MPRITASKIV
MPRITASKIVLLIALSFCITVIYHFPIATRSSKEYDEYGNEYENVASIESDIKNVRRLLDEVPDPSQNRLQFLKLDEHAFAFSAYTDDRNGNMGYKYVRVLMFITSQDNFSCEINGRKSTDVSLYEFSENHKMKWQMFILNCKLPDGIDFNNVSSVKVIRSTTKQFVDVPIRYRIQDEKIITPDEYDYKMSICVPALFGNGYDAKRIVEFIELNTLQGIEKIYIYTNQKELDGSMKKTLKYYSDNHKITLIDYTLPFREDGVWYHGQLATVTDCLLRNTGITKYTFFNDFDEFFVPVIKSRTLFETISGLFEDPTIGSQR...
glycosylation N-glycan processing protein galactosylation cytoplasm; Golgi cisterna membrane; intracellular organelle beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity glycosyltransferase activity metal ion binding UDP-galactosyltransferase activity Caenorhabditis elegansGlycoprotein Glycosy...
apoptotic cell clearance autophagy cellular response to toxic substance dauer larval development determination of adult lifespan embryo development ending in birth or egg hatching embryonic morphogenesis germ cell proliferation germ-line stem cell division nucleophagy plasma membrane repair positive regulation of autop...
cytoplasm; cytosol; extrinsic component of membrane; phagocytic vesicle; phagocytic vesicle membrane; phagophore assembly site membrane
phosphatidylinositol-3,5-bisphosphate binding phosphatidylinositol-3-phosphate binding phosphatidylinositol-4-phosphate binding phosphatidylinositol-5-phosphate binding
Caenorhabditis elegans
Alternative splicing Autophagy Cytoplasm Cytoplasmic vesicle Lipid-binding Membrane Reference proteome Repeat WD repeat
MSATTSEENP
MSATTSEENPDSINYIGFNQDSKVICVGHKDGYMFYKTADILENNTLTYEGENLTHLGLNNCLIIERLFSSALMVVISQKDPRVLHVYHFTSRNIICDHRFNKSVLTVRLNRDRIVVCLEDCIYIYNLKDMKMMHNIMDTPTNKLGVLDLTSNPGNALIAYPGSTDTGSVHLFDAINLSSVSTFNAHEGTIACLKFNQEGNMIATASTKGTVIRVYSVPNGHRLFEFRRGVTRCVNIYSLCFSSDSKYLTSSSNTETVHVFKLEKTEGVDNKPEASTEGGGWFDAINKTFSAYMPSQVLQVGELMTTERSFATAKLPGAA...
apoptotic cell clearance autophagy cellular response to toxic substance dauer larval development determination of adult lifespan embryo development ending in birth or egg hatching embryonic morphogenesis germ cell proliferation germ-line stem cell division nucleophagy plasma membrane repair positive regulation of autop...
carbohydrate transport UDP-N-acetylgalactosamine transmembrane transport UDP-N-acetylglucosamine transmembrane transport
Golgi membrane
UDP-galactose transmembrane transporter activity UDP-N-acetylgalactosamine transmembrane transporter activity UDP-N-acetylglucosamine transmembrane transporter activity
Caenorhabditis elegans
Golgi apparatus Membrane Reference proteome Sugar transport Transmembrane Transmembrane helix Transport
MNRANDTSSN
MNRANDTSSNLKLISLVVLIVQTTALVLTLRYSQTQKSEGPRYLSSTAVVCAEIIKLITCFFVIYRNNGYRFSGMLNELNREIFASPQTRADSLKVAVPAIMYVIQNNLLFFALKKLDAATYQVTYQLKILTTAIFSVTMLGKSLHRYNWMALILLTAGVALVQYPSGDSTTSKSTAAEHDASDNILGLGAVLAACFSSGFAGVYFEKILKTSKVSLWIRNIQLAFFSVFGALLVCWLYDWQAISDDGFLRGYNGVIWIVVLLQAYGGLVIALVVKYADNILKGFAVSLSIILSSFTSWLVLGDLTITTTFAIGATVVIF...
carbohydrate transport UDP-N-acetylgalactosamine transmembrane transport UDP-N-acetylglucosamine transmembrane transport Golgi membrane UDP-galactose transmembrane transporter activity UDP-N-acetylgalactosamine transmembrane transporter activity UDP-N-acetylglucosamine transmembrane transporter activity Caenorhabditis ...
actin cytoskeleton organization cell projection assembly establishment or maintenance of cell polarity mitochondrion organization muscle cell cellular homeostasis positive regulation of locomotion positive regulation of sarcomere organization striated muscle cell development substrate adhesion-dependent cell spreading
actin cytoskeleton; axon; basal plasma membrane; cytoplasm; focal adhesion; M band; perikaryon; striated muscle dense body
actin binding
Caenorhabditis elegans
Actin-binding Cell adhesion Cell projection Cytoplasm Cytoskeleton Reference proteome Repeat
MSTLGRSKTP
MSTLGRSKTPSRDEPKKPGVFEKLSGTLSRKKKAPEDEHGNQGGAHHATDEDEVLELELEGREALDQSLVPVLARNIWLEEGEIRRYLTKETARDQKLAQVVDLLIYWLNEELADQRIVVRHLQEDLFDGQIIQKLLEKLEQIRIEVPEVSQSEEGQRQKLQIVVQTANRILGQPREQEKWSADLIHQKDFTAIIQLLVLLALHYRAPVRFPDNVVANVVVAQKEHGQVKTHRITEQITTVQTELAPKGTRDAFDTLFDYGPDKLAHVKTSLLAFCNKHLNKINLEVSDLDNQFQDGVFLVLLVGLLEGYFVPLYHFNLQ...
actin cytoskeleton organization cell projection assembly establishment or maintenance of cell polarity mitochondrion organization muscle cell cellular homeostasis positive regulation of locomotion positive regulation of sarcomere organization striated muscle cell development substrate adhesion-dependent cell spreading ...
DNA amplification DNA replication initiation mitotic DNA replication checkpoint signaling
nuclear origin of replication recognition complex; nucleus
ATP binding ATP hydrolysis activity chromatin binding DNA binding metal ion binding
Drosophila melanogaster
3D-structure ATP-binding DNA replication DNA-binding Magnesium Metal-binding Nucleotide-binding Nucleus Phosphoprotein Reference proteome
MVNKENARSV
MVNKENARSVGQQVKWIGSQDELPPVKNLEHKNVYFYQKCIYGPLTLSVGDFILVSNADAAEPDTVSGCDVARILHMYELRELTDREPCRAIVQWYSWPKAIPHNKYDDDEVAIDFSLEVIEEHRPYDNDVALGAIYRKCIVLEGTSKTSAEEILKRHANKLKSTACPMFVSRYRFVKVKRSYRLIPLEIHLEQPEDNARPTRSSRKSLTAHRESKRSISARHDDTAGNKGSSVEKRRRASMAASSSVEFIDVNSFICENKVSPIKIVGGRSVVRLSEKKNAPEINANYLPASPLTEKNAKVETPKSRASAARRNLNLSL...
DNA amplification DNA replication initiation mitotic DNA replication checkpoint signaling nuclear origin of replication recognition complex; nucleus ATP binding ATP hydrolysis activity chromatin binding DNA binding metal ion binding Drosophila melanogaster 3D-structure ATP-binding DNA replication DNA-binding Magnesium ...
negative regulation of transcription by RNA polymerase II regulation of gene expression regulation of transcription by RNA polymerase II tissue development
CCAAT-binding factor complex; cytoplasm; nucleus; perikaryon
DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription repressor activity protein heterodimerization activity
Caenorhabditis elegans
Alternative splicing Cytoplasm DNA-binding Nucleus Reference proteome Repressor Transcription Transcription regulation
MSQFPEVLDN
MSQFPEVLDNNLLHAENNETAEYIQNDGTNQSEVFMEHPYTPNMHPINMPSIVEGAVHPYNNLIHHNDAIPPAKYASMRQMTEDFWREKKQKMTEISEEDMLNKSKNMSVPMARVKKIMRIDDDVRNFMIASDAPIFMAQAAEFFIEEMTAMGWQYVSEARRRILQKADIASAVQKSDQFDFLIDFLPPKTVPTTSTNGPGHMSEDSFQDPNMHSDFHQRTSNSSVNRSHHN
negative regulation of transcription by RNA polymerase II regulation of gene expression regulation of transcription by RNA polymerase II tissue development CCAAT-binding factor complex; cytoplasm; nucleus; perikaryon DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transc...
potassium ion transmembrane transport potassium ion transport regulation of muscle contraction stabilization of membrane potential
muscle cell projection membrane; plasma membrane; striated muscle dense body
outward rectifier potassium channel activity potassium channel activity potassium ion leak channel activity
Caenorhabditis elegans
Glycoprotein Ion channel Ion transport Membrane Potassium Potassium channel Potassium transport Reference proteome Transmembrane Transmembrane helix Transport
MKRQNIRTLS
MKRQNIRTLSLIVCTLTYLLVGAAVFDALETENEILQRKLVQRVREKLKTKYNMSNADYEILEATIVKSVPHKAGYQWKFSGAFYFATTVITTIGYGHSTPMTDAGKVFCMLYALAGIPLGLIMFQSIGERMNTFAAKLLRFIRRAAGKQPIVTSSDLIIFCTGWGGLLIFGGAFMFSSYENWTYFDAVYYCFVTLTTIGFGDYVALQKRGSLQTQPEYVFFSLVFILFGLTVISAAMNLLVLRFLTMNTEDERRDEQEAILAAQGLVRVGDPTADDDFGRLPLSDNVSLASCSCYQLPDEKLRHRHRKHTEPHGGPPTF...
potassium ion transmembrane transport potassium ion transport regulation of muscle contraction stabilization of membrane potential muscle cell projection membrane; plasma membrane; striated muscle dense body outward rectifier potassium channel activity potassium channel activity potassium ion leak channel activity Caen...
negative regulation of transcription by RNA polymerase II regulation of gene expression regulation of transcription by RNA polymerase II tissue development
CCAAT-binding factor complex; cytoplasm; perikaryon
DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity protein heterodimerization activity
Caenorhabditis elegans
Alternative splicing Cytoplasm DNA-binding Nucleus Reference proteome Repressor Transcription Transcription regulation
MDPKPINEGM
MDPKPINEGMLLEDHDHGMPEEEEITEDDMNGIHNIEEDTRTISEIAMELHHPNKSQVLLDQERFLPIANVVRIMKTQMDPQAKLAKDAKECAQECVSEFISFIASEAAEICNITKRKTITADDLLTAMEATGFDNYAEPMRIFLQKYRQAHKITGPIHRTHPDYVRPPQFQMDPFVRPLFFDTEQGRRCTETQYVINGSEIVKNAPLGEEWNEQTGTLNTRADGYYMEEPMEPMPMEEVEIEEHEEIIEQDSLGAIALEQQGQMQIYVDPKTKQHFAAKETPNGMELYPLIIQDTPLQLENVSGPNQFVMNMPDGRAIP...
negative regulation of transcription by RNA polymerase II regulation of gene expression regulation of transcription by RNA polymerase II tissue development CCAAT-binding factor complex; cytoplasm; perikaryon DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription f...
chromatin organization negative regulation of transcription by RNA polymerase II receptor guanylyl cyclase signaling pathway regulation of neuron differentiation signal transduction
cytoplasm; histone deacetylase complex; nucleus
calmodulin binding histone deacetylase activity RNA polymerase II-specific DNA-binding transcription factor binding transcription corepressor activity
Caenorhabditis elegans
Alternative splicing Chromatin regulator Hydrolase Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation
MEEASSSTGS
MEEASSSTGSAGGAGPSVPNLPSTSEAAIGQTNLEPESIALLQSQLQEYRQKQMDLIGHFQRAQQELSVQHMHNLYAALQQQQQLQNLQTERSAVNPLLISQQHSTEDQNSGPAAPLSLANSLTNLLSSSNGNLSVPQTPTKEHHPTAPTSNRKCDLPRSNSTTISQLTKDRLKNMIANRSKGESNSQSNLMSNSVTANGNGHDNGRKLKNSNSQVNVSSPHFEPYRLPTSLANAHNLQQASEFQLRKVNSEPNLKMRIRAKLLSKGSSPVQHVQQNNSQFNFTHPQLKRSDSETSQNVPLDFMQSSSQTNLPHLMLPSP...
chromatin organization negative regulation of transcription by RNA polymerase II receptor guanylyl cyclase signaling pathway regulation of neuron differentiation signal transduction cytoplasm; histone deacetylase complex; nucleus calmodulin binding histone deacetylase activity RNA polymerase II-specific DNA-binding tra...
apoptotic process involved in development embryo development ending in birth or egg hatching engulfment of apoptotic cell execution phase of apoptosis phosphatidylserine exposure on apoptotic cell surface programmed cell death
plasma membrane
phospholipid scramblase activity
Caenorhabditis elegans
Apoptosis Cell membrane Membrane Reference proteome Transmembrane Transmembrane helix
MFLKKHKSKL
MFLKKHKSKLLLVPRDEEQEDAGIVAVLTDRIPSVLLVRWFDLFCFGFAMCSYALDFFSDIGIAIFHFWAGRYLSGSLVLAFALLPSVIINIISMVWMLDDEMHWKRRAHPRRTGTFELNQKRFIPLSKMIVLCICQMGPLFWYYKALYYGWMFRKSSNENTDGEKRKCFSKMVEAERDATLLRFFEAFLESAPQLIIQGSIAASYFQNYYQTGTYPYWLYFQAASLLLSIISISWSVVVQNRSLRMIRDDKVNIWPHEAVLQFCWRFLTILARIITLVALVLIFGINVVPLISVHLLVTLVHVIFLQAIHIDACTHIEK...
apoptotic process involved in development embryo development ending in birth or egg hatching engulfment of apoptotic cell execution phase of apoptosis phosphatidylserine exposure on apoptotic cell surface programmed cell death plasma membrane phospholipid scramblase activity Caenorhabditis elegansApoptosis Cell membran...
actin filament organization
anchoring junction; cell cortex; cytoskeleton; cytosol
actin monomer binding
Caenorhabditis elegans
Actin-binding Cell junction Cytoplasm Cytoskeleton Reference proteome Repeat
MAAVTELPKM
MAAVTELPKMNQELAGAVREGLELKKVETTEKNVLPTKEDVAEEKQHVERIHEIEHFDSTKLHSTPVKEKIVLPSADDIKQEKQHLELTDKINNFPSENLKKTETIEKNVLPSPTDVAREKTLQMAASFDKSALHHVETIVSTDVRVTEAQ
actin filament organization anchoring junction; cell cortex; cytoskeleton; cytosol actin monomer binding Caenorhabditis elegansActin-binding Cell junction Cytoplasm Cytoskeleton Reference proteome Repeat MAAVTELPKM MAAVTELPKMNQELAGAVREGLELKKVETTEKNVLPTKEDVAEEKQHVERIHEIEHFDSTKLHSTPVKEKIVLPSADDIKQEKQHLELTDKINNFPSENLKKTET...
epigenetic regulation of gene expression gamete generation germ cell development germ-line stem cell division heterochromatin formation methylation negative regulation of gene expression regulation of gene expression regulation of transcription by RNA polymerase II tissue development
ESC/E(Z) complex; nucleosome; nucleus; PcG protein complex
chromatin binding histone H3K27 methyltransferase activity histone H3K27 trimethyltransferase activity histone methyltransferase activity
Caenorhabditis elegans
Developmental protein Methyltransferase Nucleus Reference proteome Repressor S-adenosyl-L-methionine Transcription Transcription regulation Transferase
MSNSEPSTST
MSNSEPSTSTPSGKTKKRGKKCETSMGKSKKSKNLPRFVKIQPIFSSEKIKETVCEQGIEECKRMLKGHFNAIKDDYDIRVKDELDTDIKDWLKDASSSVNEYRRRLQENLGEGRTIAKFSFKNCEKYEENDYKVSDSTVTWIKPDRTEEGDLMKKFRAPCSRIEVGDISPPMIYWVPIEQSVATPDQLRLTHMPYFGDGIDDGNIYEHLIDMFPDGIHGFSDNWSYVNDWILYKLCRAALKDYQGSPDVFYYTLYRLWPNKSSQREFSSAFPVLCENFAEKGFDPSSLEPWKKTKIAEGAQNLRNPTCYACLAYTCAIH...
epigenetic regulation of gene expression gamete generation germ cell development germ-line stem cell division heterochromatin formation methylation negative regulation of gene expression regulation of gene expression regulation of transcription by RNA polymerase II tissue development ESC/E(Z) complex; nucleosome; nucle...
anterior/posterior axon guidance cell division chromosome segregation dorsal/ventral axon guidance egg-laying behavior maintenance of mitotic sister chromatid cohesion
axon; chromatin; cytoplasm; nucleoplasm; nucleus; SMC loading complex
double-stranded DNA binding
Caenorhabditis elegans
Cell cycle Cell division Chromosome partition Cytoplasm Developmental protein Mitosis Nucleus Reference proteome
MNQDAVAKAL
MNQDAVAKALLGMAEALRTQDPPKLKMAIKCARSTLSMEISDEMKAICNLQLGKLLFFYTDNFELAKNHLQCAYDKMSAMGTFYTRDKMNAISMLADLHIHYQQWPLTSIKATIRHEITTTRGFPALSNKLMFQLIELMKIDKDVEGAIEMCQLAINSSHADPKMELYFRIAKTLVTYQLMHEEPDISDVTRIGSMIKVMENSTTSDKAHLECIKDFYVCTKLAYMFYEGKSRTSRQLLRQIQKSQTSGETKIHGIRWLGEPSITLLACVMNQICALVQSNTDRVEKYYHLVIKHADEIIFKSTRSPQEPGVVRCINMIK...
anterior/posterior axon guidance cell division chromosome segregation dorsal/ventral axon guidance egg-laying behavior maintenance of mitotic sister chromatid cohesion axon; chromatin; cytoplasm; nucleoplasm; nucleus; SMC loading complex double-stranded DNA binding Caenorhabditis elegansCell cycle Cell division Chromos...
chemical synaptic transmission nervous system development neuron-neuron synaptic transmission positive regulation of backward locomotion positive regulation of vulval development protein localization protein localization to basolateral plasma membrane protein localization to early endosome receptor localization to syna...
cytoplasm; dendrite; dendritic spine; Golgi apparatus; Golgi cisterna membrane; Golgi trans cisterna; neuron projection; neuronal cell body; perikaryon; plasma membrane; synapse; trans-Golgi network transport vesicle
small GTPase binding
Caenorhabditis elegans
Alternative splicing Cytoplasm Developmental protein Golgi apparatus Hydroxylation Membrane Neurogenesis Phosphoprotein Reference proteome Repeat Synapse Transport
MSSEAVAQAT
MSSEAVAQATAATTSPEHGVPTSSATPTPPPSKGGGAGGGGGGEQQQVPFQMIPPGHFFANPFLNPYIPTAGAPAQEGEAQPQMVFSPAQYQEVMHHYFQQMMAASGAQFPIPFPMQFQPALQQPRPSSQASSSHRSEDDNGRQTAGSVVSSNVSPNHREVRPAEDSTETSGVVQNNDELLVPTSTSSDVTIGDVIEKSDSPENSQESAGGEEKSEEKRKLSGDRTDSLIRKQMSEMEKEITRRSQNKNIKTIDDDGLAELIGGSSTRTVADDFSPFVDKSGLSYTAPAPPSTEKSAPKESLNQLRSSFNLPDDSTTVGP...
chemical synaptic transmission nervous system development neuron-neuron synaptic transmission positive regulation of backward locomotion positive regulation of vulval development protein localization protein localization to basolateral plasma membrane protein localization to early endosome receptor localization to syna...
box C/D snoRNP assembly chromatin remodeling DNA repair nematode larval development positive regulation of translation regulation of transcription by RNA polymerase II TOR signaling
cytoplasm; Ino80 complex; NuA4 histone acetyltransferase complex; nucleus; R2TP complex; Swr1 complex
ATP binding ATP hydrolysis activity DNA helicase activity
Caenorhabditis elegans
ATP-binding Chromatin regulator Cytoplasm DNA damage DNA repair Helicase Hydrolase Nucleotide-binding Nucleus Reference proteome Transcription Transcription regulation
MDMEVDEAIS
MDMEVDEAISGTSSSRLAPIEEVKPTPKQIKRIAAHSHVKGLGIDTETQEAHYEAAGFVGQAPARTAASIVVDMIRLKCMAGRAVLIAGPPATGKTAIALAMSQELGDGVPFVPLVASEVFSNEVKKTEVLMRSFRRAIGLRVKETKDVYEGEVTELSPVEASDNSGMGKTISHLVLSLKTAKGSKQLKLDPSIYDSILKQRVEVGDVIYIEANSGIVKRVGRCDVYASEFDLEADEFVPMPKGDVRKSKDIVQNVSLHDLDIANARPQGRQGDVSNIVSQLMTPKKTEVTDRLRSEINKVVNEYIESGVAELMPGVLFI...
box C/D snoRNP assembly chromatin remodeling DNA repair nematode larval development positive regulation of translation regulation of transcription by RNA polymerase II TOR signaling cytoplasm; Ino80 complex; NuA4 histone acetyltransferase complex; nucleus; R2TP complex; Swr1 complex ATP binding ATP hydrolysis activity ...
de novo' pyrimidine nucleobase biosynthetic process CDP biosynthetic process phosphorylation UDP biosynthetic process
cytoplasm; nucleus
ATP binding CMP kinase activity cytidylate kinase activity dCMP kinase activity UMP kinase activity
Caenorhabditis elegans
ATP-binding Cytoplasm Kinase Nucleotide-binding Nucleus Pyrimidine biosynthesis Reference proteome Transferase
MYNVVFVLGP
MYNVVFVLGPPGSGKGTICTQIHENLGYVHLSAGDLLRAERERAGSEYGALIEGHIKNGSIVPVEITCALLENAMIASKDANGFLIDGFPRNEDNWSGWNKQMGGKVNEQFVLFLSCPVDVCIDRCLHRGQGRTDDNVESLKKRVETYNQSTFPIIEHFEKVGMVREVNSERPVTEVYEDVVKVFAAANQK
de novo' pyrimidine nucleobase biosynthetic process CDP biosynthetic process phosphorylation UDP biosynthetic process cytoplasm; nucleus ATP binding CMP kinase activity cytidylate kinase activity dCMP kinase activity UMP kinase activity Caenorhabditis elegansATP-binding Cytoplasm Kinase Nucleotide-binding Nucleus Pyrim...
heparan sulfate proteoglycan biosynthetic process, enzymatic modification heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process positive regulation of multicellular organism growth regulation of axon guidance regulation of cell migration
Golgi apparatus; Golgi membrane
heparan sulfate 2-O-sulfotransferase activity
Caenorhabditis elegans
Developmental protein Disulfide bond Glycoprotein Golgi apparatus Membrane Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix
MLWKKRKVLY
MLWKKRKVLYFAGISVFILILLLLKLNSKPKANVWPTSSKIVIYNRIPKTGSTTFTNAIAYDLYKENGFSVLHVNMTKNRQVMSLPDQYTFVNNITTWTERLPAFYHGHVAFIDFQRFGIANPIYINIIREPLERLLSHYYFLRYGDNYRIGLKRSRAGNNETFDECYSRGGKDCDMKQMWIQIPYFCGHYHFCTEVGNPEALRVAKQNVLEKYLLVGTTSRMRDMIALLEVTVPDFFKGALGHFDSLDANRAHLRYTKKKIPPNDQTLSMIRRDEVYKMEREFYDFINNLFDAVFKKATNGISKADDLVKLPLQYHFEK...
heparan sulfate proteoglycan biosynthetic process, enzymatic modification heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process positive regulation of multicellular organism growth regulation of axon guidance regulation of cell migration Golgi apparatus; Golgi membrane heparan sul...
anatomical structure development cell differentiation egg-laying behavior embryonic morphogenesis locomotion mesodermal cell fate specification negative regulation of apoptotic process negative regulation of extrinsic apoptotic signaling pathway in absence of ligand nematode larval development positive regulation of ap...
nucleus
metal ion binding protein tyrosine phosphatase activity transcription coactivator activity
Caenorhabditis elegans
Alternative splicing Developmental protein Hydrolase Magnesium Metal-binding Nucleus Protein phosphatase Reference proteome Transcription Transcription regulation
MLPDSEGQKL
MLPDSEGQKLKTFLLGTGTTLDPSLDPTGNSNFSMATTSDSSTIWTALPASQPGDKDIPTVDLAAISEAYGSTSSTTSLTSSVTSQYQYNSYPQYAMYTSANPANYYQQVTANLRAGTTAFPYSLTTPSYYGSYPVDYTSAAAAYQNPYYTNLRGGTAAPYYNPLNATTAAAYASVASSVLGTDAVNLGTSSDGSTGVPSTVTSFSLKEKKPKVSKKKKTGSCSPGDETYARVFIWDIDDIAVISRNYLASVTHTNEFYARAANSVSHLMERIALNNFADVNEFLEGDITNIEDAVVDETTMDSGPIDNLRGLDVMRRVA...
anatomical structure development cell differentiation egg-laying behavior embryonic morphogenesis locomotion mesodermal cell fate specification negative regulation of apoptotic process negative regulation of extrinsic apoptotic signaling pathway in absence of ligand nematode larval development positive regulation of ap...
epigenetic regulation of gene expression methylation
chromatin; nucleus
histone H3K9 dimethyltransferase activity histone H3K9 trimethyltransferase activity histone H3K9me2 methyltransferase activity
Caenorhabditis elegans
Chromosome Methyltransferase Nucleus Reference proteome S-adenosyl-L-methionine Transferase
MERSRTGGSS
MERSRTGGSSTYSMSTANVPIITISDDDDELTIWEEPRKSPISSNSYSDERNHSLSSTSNSSVERSIIITISDDESEATERNQQEVVDRAISNNLTEKRRRSVESFHRLHSKERKLEVKSRKKSRTSSSSMEASTSCTFPARQTKTKRHKRKTYSTISSFAPHHSTICAELRNVNPARIADFRHPSIFEYSDMSLNERREHWKKEMKVIKKHNDIRLMHEEAVRFDDIIELDPTLNGYYRRFMGAEQSTRALFMAVRCLATFGRNFYEEPERDHGEEEIPEELDRYFEKLIYVAPRTRIRITDDIHLSNDTHRIPVYTDA...
epigenetic regulation of gene expression methylation chromatin; nucleus histone H3K9 dimethyltransferase activity histone H3K9 trimethyltransferase activity histone H3K9me2 methyltransferase activity Caenorhabditis elegansChromosome Methyltransferase Nucleus Reference proteome S-adenosyl-L-methionine Transferase MERSRT...
cell differentiation chromatin organization determination of adult lifespan embryo development ending in birth or egg hatching embryonic digestive tract morphogenesis gonad development hermaphrodite somatic sex determination mitochondrial unfolded protein response negative regulation of Notch signaling pathway negative...
chromatin; cytoplasm; germ cell nucleus; histone deacetylase complex; nucleus; NuRD complex
histone deacetylase activity RNA polymerase II-specific DNA-binding transcription factor binding
Caenorhabditis elegans
Chromatin regulator Chromosome Cytoplasm Developmental protein Hydrolase Nucleus Reference proteome Repressor Transcription Transcription regulation Ubl conjugation
MNSNGPLMEH
MNSNGPLMEHGKRRVAYYYDSNIGNYYYGQGHVMKPHRIRMTHHLVLNYGLYRNLEIFRPFPASFEDMTRFHSDEYMTFLKSANPDNLKSFNKQMLKFNVGEDCPLFDGLYEFCQLSSGGSLAAATKLNKQKVDIAINWMGGLHHAKKSEASGFCYTNDIVLGILELLKYHKRVLYVDIDVHHGDGVEEAFYTTDRVMTVSFHKYGDFFPGTGDLKDIGAGKGKLYSVNVPLRDGITDVSYQSIFKPIMTKVMERFDPCAVVLQCGADSLNGDRLGPFNLTLKGHGECARFFRSYNVPLMMVGGGGYTPRNVARCWTYET...
cell differentiation chromatin organization determination of adult lifespan embryo development ending in birth or egg hatching embryonic digestive tract morphogenesis gonad development hermaphrodite somatic sex determination mitochondrial unfolded protein response negative regulation of Notch signaling pathway negative...
acetylcholine secretion, neurotransmission cellular response to carbon dioxide larval feeding behavior negative regulation of nematode pharyngeal pumping neuropeptide processing peptide metabolic process positive regulation of acetylcholine secretion, neurotransmission positive regulation of defecation positive regulat...
axon; cytoplasmic vesicle; extracellular space; neuronal cell body; perikaryon; presynapse
carboxypeptidase activity metallocarboxypeptidase activity zinc ion binding
Caenorhabditis elegans
Carboxypeptidase Cell projection Cytoplasmic vesicle Glycoprotein Hydrolase Metal-binding Metalloprotease Protease Reference proteome Signal Zinc
MLHAMRPVLL
MLHAMRPVLLVAALLAVTAHAFLGFGSGSTHKDDAEWGHYHNQAQLEAKLGEINEKCPEITTLYEIGQSVEGRPLVVIQFSTTPGEHIPTKPEVKLIGNMHGNEPIGRELLLRFAETLCNGAINNDKEIVQLLNSTSIHILPSMNPDGFELALGTEPAQRQWLTGRSNINGVDLNRDFPDLDSIFYELQKIGVPKFDHLLSLFEDNVDRQPETIAVGQWTLSLPFVLSANFHEGDLVANYPFDAAIDENSQKTAYSASPDDGTFRWLAKSYADNHAHMSKNDHAPCDGTSQDAFARQGGITNGAKWYSVAGGMQDFNYLA...
acetylcholine secretion, neurotransmission cellular response to carbon dioxide larval feeding behavior negative regulation of nematode pharyngeal pumping neuropeptide processing peptide metabolic process positive regulation of acetylcholine secretion, neurotransmission positive regulation of defecation positive regulat...
dendrite morphogenesis dendrite self-avoidance gene expression insulin processing negative regulation of dauer entry negative regulation of protein localization to cell surface peptide hormone processing positive regulation of dendrite development positive regulation of dendrite extension positive regulation of dendrit...
axon; membrane; neuronal cell body; perikaryon; plasma membrane; trans-Golgi network
metal ion binding serine-type endopeptidase activity signaling receptor binding
Caenorhabditis elegans
Calcium Cell membrane Cell projection Cleavage on pair of basic residues Disulfide bond Glycoprotein Hydrolase Membrane Metal-binding Protease Reference proteome Serine protease Signal Transmembrane Transmembrane helix Zymogen
MSNISWYRHC
MSNISWYRHCSVRLQLVTLALFLLLGSASLGSAHIDEEFEDDVTTTISSIASPMRRTYTNEWAVRIAGGKVEEANRLANKYGYTNLGPIIPGDEYYLFRDDRKKSRSSRKTRSLSANQLQHEEDVMWMEQQVAKRRVKRGYRRIRRHTDDNDIFEEDDDGTQISKSRNRKHPDPNDPLWTDMWYLNRGEHHSDSTTRMDHNVKEAWDLGYTGKGVVVTILDDGLERTHPDISPNYDERASYDVNDRDNDPMPRYEFSDENRHGTRCAGEVAAIFNNSLCIVGIAYNANIGGIRMLDGDVTDAVEAASVGHNADYIDIYSA...
dendrite morphogenesis dendrite self-avoidance gene expression insulin processing negative regulation of dauer entry negative regulation of protein localization to cell surface peptide hormone processing positive regulation of dendrite development positive regulation of dendrite extension positive regulation of dendrit...
chemical synaptic transmission proteolysis
cytoplasm; nucleolus; nucleus; synapse
cysteine-type deubiquitinase activity
Caenorhabditis elegans
Cytoplasm Hydrolase Nucleus Protease Reference proteome Repeat Thiol protease Transcription Transcription regulation Ubl conjugation pathway
MSKDDPINSI
MSKDDPINSIFFEHQEAALCAQHALNMLLQDALYKWQDLRDLAIQMDKMEQQILGNANPTPGRSENMNESGYFSIQVLEKALETFSLKLTNIENPAMVDYKNNPLTARAYICNLREHWFVLRKFGNQWFELNSVNRGPKLLSDTYVSMFLHQVSSEGYSIFVVQGVLPRSDADDLISLCPVVPPKVTPKKEQKLEKVMTKFFNTVGKRLGGGSGAPPDSQEEKDLAIAFAMSMETKDGSEVSRSSAEIDEENLRKAIELSQAPGPSEPAEIPLLTRSRSSTPPGASEPFSNAEQQRRDRQKFLERFEKKKEERNDEK
chemical synaptic transmission proteolysis cytoplasm; nucleolus; nucleus; synapse cysteine-type deubiquitinase activity Caenorhabditis elegansCytoplasm Hydrolase Nucleus Protease Reference proteome Repeat Thiol protease Transcription Transcription regulation Ubl conjugation pathway MSKDDPINSI MSKDDPINSIFFEHQEAALCAQHALN...
axon guidance egg-laying behavior locomotion mesodermal cell migration neuron migration positive regulation of locomotion regulation of cell migration regulation of nematode male tail tip morphogenesis regulation of transcription by RNA polymerase II
nucleus; transcription regulator complex
DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding
Caenorhabditis elegans
Developmental protein DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation
MTDHPPIDTS
MTDHPPIDTSSYFDCYQQHQLPLQYTFTSSSNSNTSNSSTSPSHISDQFSSSGGPPYELSSHILTPSSVIPTPSPSVASASISSPTIPAFGCTMSEYSMEQMEAISTSLFQARDGDRLVAFFKQLESLYGPNAVDHLRSEAIIVAYTYALYHSNEFETLFHLLSNRHFQQRHYNDLQDIWHHARYKESQLKRGKELNPVEKYRLRRKFPAPKTIWDGEEIVYSFKDSSRKFLKQFFRNVSEYPTQEQKREISRATGLKIVQISNWFKNRRQRDKSNNSAKCSPPSSSSSTNGGSDFLPIITPQSFNLAAAPFNMNMIYGT...
axon guidance egg-laying behavior locomotion mesodermal cell migration neuron migration positive regulation of locomotion regulation of cell migration regulation of nematode male tail tip morphogenesis regulation of transcription by RNA polymerase II nucleus; transcription regulator complex DNA-binding transcription fa...
chromosome segregation DNA replication DNA topological change
chromosome; nucleolus; nucleus; spindle pole centrosome
DNA binding DNA topoisomerase type I (single strand cut, ATP-independent) activity
Caenorhabditis elegans
Alternative splicing Chromosome DNA-binding Isomerase Nucleus Reference proteome Topoisomerase
MSVVSNHHSN
MSVVSNHHSNGNGNSTVYDTNGNDEIKKEVKDEPMASDSEVPFGELMKRDKKEKKQKKRKAESGSDEDDYKPEKRKSSAKNGKKKDVGSDSEDDYKPEKKKSKKNNKKKAQESSEDDDEESEGDVSEEDVKPQIHSDDELEEEDEAPTTDDEEEQKRKEKERRKKEKREKKERKEKKRLEKENRKIKEEDDEDSDDEDDEKAKKKKRKSKGAEKSKPSTSKKDAGGKKEPPKKKVKKEEDIEDIWEWWKEEKKPAGVKWNSLQHCGPLFAPPYIPLPSHVHFKYGGEKMKLTLETEEIAQFYAGVLDHEYSTKEAFNKNF...
chromosome segregation DNA replication DNA topological change chromosome; nucleolus; nucleus; spindle pole centrosome DNA binding DNA topoisomerase type I (single strand cut, ATP-independent) activity Caenorhabditis elegansAlternative splicing Chromosome DNA-binding Isomerase Nucleus Reference proteome Topoisomerase MS...
chromosome organization chromosome segregation determination of adult lifespan DNA damage checkpoint signaling DNA unwinding involved in DNA replication double-strand break repair via homologous recombination meiotic cell cycle meiotic chromosome separation meiotic DNA double-strand break processing involved in recipro...
chromosome; cytoplasm; nucleus
3'-5' DNA helicase activity ATP binding ATP hydrolysis activity ATP-dependent activity, acting on DNA DNA binding enzyme binding four-way junction helicase activity metal ion binding
Caenorhabditis elegans
ATP-binding Chromosome DNA damage DNA repair DNA replication DNA-binding Helicase Hydrolase Metal-binding Nucleotide-binding Nucleus Reference proteome Repeat Zinc
MIKNREIEVA
MIKNREIEVAPPRRTIQFGGYTFVEPDLNFKAPIFSCCGSIRDPSCEEREEEYIDNGHDEEPPVEVNRIQESTSFDEPVSSPPRYRPSENPGPSSSSYEPGHYSFNEYQQFPSRPQKRLVDPPIVDLDEEPPIVDLDDSFDNFHVGSTSEEVVSGDIAPEEEEEEGHDSFDDFESVPAQPPSKNTLASLQKSDSEIALNQQRHDMHGRFRGFLQDDSEEFSDEVGLLGADMNKELYDTLKSKFGFNQFRHRQKQCILSTLMGHDTFVLMPTGAGKSLCYQLPAVILPGVTVVVSPLRSLIEDQKMKMKELGIGCEALTAD...
chromosome organization chromosome segregation determination of adult lifespan DNA damage checkpoint signaling DNA unwinding involved in DNA replication double-strand break repair via homologous recombination meiotic cell cycle meiotic chromosome separation meiotic DNA double-strand break processing involved in recipro...
dauer larval development determination of adult lifespan negative regulation of insulin receptor signaling pathway P granule assembly regulation of lipid storage response to heat signal transduction
cytosol; nucleus; protein phosphatase type 2A complex
protein kinase binding protein phosphatase activator activity
Caenorhabditis elegans
Cytoplasm Reference proteome
MHGSGHSLTG
MHGSGHSLTGAPHQIPPPRTQGAATGGQQLSATANQFVDKIDPFHNKRGTSRRLRINNSSRYNVDSAQELVQLALIKDTAANEQPALVIEKLVQCQHVFDFYDPVAQLKCKEIKRAALNELIDHITSTKGAIVETIYPAVIKMVAKNIFRVLPPSENCEFDPEEDEPTLEVSWPHLQLVYELFLRFLESPDFQASIGKKYIDQRFVLKLLDLFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKHINNMFLRFVYETDSFNGVGELLEILGSIINGFALPLKQEHKVFLVKVLLPLHKPKCLSLYHAQLAYCVVQFIEKD...
dauer larval development determination of adult lifespan negative regulation of insulin receptor signaling pathway P granule assembly regulation of lipid storage response to heat signal transduction cytosol; nucleus; protein phosphatase type 2A complex protein kinase binding protein phosphatase activator activity Caeno...
Arp2/3 complex-mediated actin nucleation cytoplasmic sequestering of protein determination of adult lifespan endocytic recycling exocytosis regulation of gene expression retrograde transport, endosome to Golgi
cytosol; early endosome; recycling endosome; WASH complex
actin binding alpha-tubulin binding gamma-tubulin binding
Caenorhabditis elegans
Actin-binding Reference proteome
MYHVPLIPRD
MYHVPLIPRDAGREETIFRINQSLQKLLRVSDEIFDRVEHRITRIHGKAEAIDRRTEVLEKKLESLQESDKVITFTLPRQLPKLPEEPPTSTSLFRINIDTEHFPGSEELPAFRRADDHVLRPCEPIDFTYELNKPDKFFLTSQVLKEYEQKGWERYKKRLLGGLRELSRSPEHIAELFYAGTSIPAFEGVSGDFSKKALDADDDGGTSRSGRTTDELAQLRLHEQLLEDTALSSTLMQEDSLDDNHPLAFRINFNEKKKKTAKMVEMPDSLPNLKGHAHDFTLRDPEIDEDRLLDILPADDQIPEASEPTEAEADAPTT...
Arp2/3 complex-mediated actin nucleation cytoplasmic sequestering of protein determination of adult lifespan endocytic recycling exocytosis regulation of gene expression retrograde transport, endosome to Golgi cytosol; early endosome; recycling endosome; WASH complex actin binding alpha-tubulin binding gamma-tubulin bi...
embryo development ending in birth or egg hatching meiotic cell cycle meiotic nuclear membrane disassembly negative regulation of G2/MI transition of meiotic cell cycle negative regulation of meiotic cell cycle process involved in oocyte maturation negative regulation of ovulation nematode larval development nematode m...
condensed chromosome; cytoplasm; extrinsic component of membrane; Golgi membrane; nuclear envelope; nucleus; perinuclear endoplasmic reticulum; plasma membrane
ATP binding cyclin-dependent protein serine/threonine kinase inhibitor activity metal ion binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity
Caenorhabditis elegans
ATP-binding Cell cycle Cytoplasm Developmental protein Differentiation Golgi apparatus Kinase Magnesium Membrane Metal-binding Nucleotide-binding Oogenesis Reference proteome Serine/threonine-protein kinase Spermatogenesis Transferase
MDDTEGNSSM
MDDTEGNSSMDSIRNGQSSPLPQVTPRLPQIPMMMRETPLSTKRERQAITPRFRRPAPKMIKTMPPTRSIWSVRKESVPLLVTPQGPKPLESPKYDHTNAQSFFEQVFQIDEIIGRGSFGEVFAARCREDSQLYAVKVSLAPIRQHSISKYREAESHMIIPPHKNLVKFYRAWEETGRLYIQTELCDQSLLKYCTEKHALPEDEIWNIFVDLLQAVHHLHSNDMIHDDIKPENIFLTKDMICKLGDFGLVINLKNPNDVKSAEEGDSKYLAPEVLNGRPTKSSDIFSLGMTILEATTDLDVPSNGDSWHQIRNGQIPDRF...
embryo development ending in birth or egg hatching meiotic cell cycle meiotic nuclear membrane disassembly negative regulation of G2/MI transition of meiotic cell cycle negative regulation of meiotic cell cycle process involved in oocyte maturation negative regulation of ovulation nematode larval development nematode m...
cell differentiation negative regulation of transcription by RNA polymerase II nematode male tail tip morphogenesis positive regulation of nematode male tail tip morphogenesis positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II sex differentiation
nucleus
DNA-binding transcription factor activity, RNA polymerase II-specific metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding
Caenorhabditis elegans
Alternative splicing Developmental protein Differentiation DNA-binding Metal-binding Nucleus Reference proteome Repeat Sexual differentiation Zinc
MLTEDPVSEI
MLTEDPVSEICEAKAVDELAEQEKNYYCQRCLNHGELKPRKGHKPDCRYLKCPCRECTMVEQRRQLNNLLSKKKIHCTPATQTRDGKRVRDPHCARCSAHGVLVPLRGHKRTMCQFVTCECTLCTLVEHRRNLMAAQIKLRRSQQKSRDGKEPKRNSRRKSKDMDMEMMVVTATDGQKIIGTSASPSPSSTTDTMSPSLSMSPPCSPSPLLAQYTLTLAAPIPIYPPIPMNQQLISLQQQQFLMSIIQNMAPSIGQQAPLLPGISAGSVSSAAILNEFWSMYLKNYGLQA
cell differentiation negative regulation of transcription by RNA polymerase II nematode male tail tip morphogenesis positive regulation of nematode male tail tip morphogenesis positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II sex differentiation nucleus DNA-bindi...
chemical synaptic transmission chloride transmembrane transport monoatomic ion transport
chloride channel complex; GABA-A receptor complex; neuron projection; postsynaptic membrane; synapse
chloride channel activity extracellular ligand-gated monoatomic ion channel activity GABA-A receptor activity neurotransmitter receptor activity
Caenorhabditis elegans
Cell membrane Chloride Chloride channel Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport
MRRSKTRRIF
MRRSKTRRIFHVSITLLLVSTIFCQNGTKPHNNSTSDQMSSSWSNRSQTMYSNASSLLSDLLLDYDIRLRPGFGGDALLLTMDIIIASFDSISEVDMDYTLTMYLHQYWTDERLRWSNEIPIDEMTLSGEFSQNIWVPDTFLANDKHSYLHEVTERNKMLRINVDGKVAYGMRLTSTLSCSMNLRNFPLDSQNCTVEIESYGYTTSEVLMKWNYPLAVHGVEQADVPQFTITGFHTEDSIVSTATGSYQRLSLVFQLRRSVGYFIFQTYLPCVLIVMLSWVSFWINHEATSARVALGITTVLTMTTISTGVRQSLPRISY...
chemical synaptic transmission chloride transmembrane transport monoatomic ion transport chloride channel complex; GABA-A receptor complex; neuron projection; postsynaptic membrane; synapse chloride channel activity extracellular ligand-gated monoatomic ion channel activity GABA-A receptor activity neurotransmitter rec...
endoplasmic reticulum to Golgi vesicle-mediated transport protein secretion Rab protein signal transduction regulation of glutamate receptor clustering regulation of postsynapse organization vesicle-mediated transport viral entry into host cell
cytoplasmic vesicle; endoplasmic reticulum exit site; Golgi apparatus; Golgi membrane; neuronal cell body; perikaryon; plasma membrane; postsynapse of neuromuscular junction; presynaptic active zone; type II terminal bouton; vesicle
GTP binding GTPase activity metal ion binding
Drosophila melanogaster
3D-structure Cell projection Cytoplasmic vesicle ER-Golgi transport Golgi apparatus GTP-binding Hydrolase Magnesium Metal-binding Nucleotide-binding Protein transport Reference proteome Synapse Transport
MSYAYLFKYI
MSYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQEAFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSNSNMVIMLIGNKSDLDSRREVKKEEGEAFAREHGLVFMETSARTAANVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGQQHSPTNPSLPGAGGAAGAANSGCC
endoplasmic reticulum to Golgi vesicle-mediated transport protein secretion Rab protein signal transduction regulation of glutamate receptor clustering regulation of postsynapse organization vesicle-mediated transport viral entry into host cell cytoplasmic vesicle; endoplasmic reticulum exit site; Golgi apparatus; Golg...
axon guidance compound eye morphogenesis defense response to fungus exocytosis germarium-derived egg chamber formation intra-Golgi vesicle-mediated transport intracellular protein transport oocyte microtubule cytoskeleton polarization phototransduction pole plasm oskar mRNA localization protein targeting to Golgi appar...
autophagosome; cytoplasmic vesicle; cytosol; endomembrane system; Golgi apparatus; Golgi membrane; lysosome; neuronal cell body; perikaryon; synapse
actin binding GTP binding GTPase activity
Drosophila melanogaster
3D-structure Actin-binding ER-Golgi transport Golgi apparatus GTP-binding Membrane Nucleotide-binding Reference proteome Synapse Transport
MSSGDFGNPL
MSSGDFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNTNSFHQTSKWIDDVRTERGSDVIIMLVGNKTDLSDKRQVSTEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMDSTENKPSEDMQEVVLKDSPNETKDPEGGCAC
axon guidance compound eye morphogenesis defense response to fungus exocytosis germarium-derived egg chamber formation intra-Golgi vesicle-mediated transport intracellular protein transport oocyte microtubule cytoskeleton polarization phototransduction pole plasm oskar mRNA localization protein targeting to Golgi appar...
adult walking behavior anatomical structure development brain development brain morphogenesis central complex development compound eye development compound eye morphogenesis eye-antennal disc morphogenesis glial cell migration glucose homeostasis mushroom body development neuron differentiation photoreceptor cell fate ...
nucleus
DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific DNA binding
Drosophila melanogaster
Alternative splicing Developmental protein DNA-binding Homeobox Nucleus Paired box Reference proteome Transcription Transcription regulation
MRNLPCLGTA
MRNLPCLGTAGGSGLGGIAGKPSPTMEAVEASTASHRHSTSSYFATTYYHLTDDECHSGVNQLGGVFVGGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATAEVVSKISQYKRECPSIFAWEIRDRLLQENVCTNDNIPSVSSINRVLRNLAAQKEQQSTGSGSSSTSAGNSISAKVSVSIGGNVSNVASGSRGTLSSSTDLMQTATPLNSSESGGASNSGEGSEQEAIYEKLRLLNTQHAAGPGPLEPARAAPLVGQSPNHLGTRSSHPQLVHGNHQALQQHQQQSWP...
adult walking behavior anatomical structure development brain development brain morphogenesis central complex development compound eye development compound eye morphogenesis eye-antennal disc morphogenesis glial cell migration glucose homeostasis mushroom body development neuron differentiation photoreceptor cell fate ...
chorion-containing eggshell formation mitotic cell cycle NLS-bearing protein import into nucleus protein import into nucleus regulation of nucleocytoplasmic transport
cytoplasm; nuclear envelope; nucleoplasm; nucleus; P granule
nuclear import signal receptor activity nuclear localization sequence binding small GTPase binding
Drosophila melanogaster
Cytoplasm Protein transport Reference proteome Repeat Transport
MTSDIAMQLI
MTSDIAMQLIAILEKTVSPDKNELLSAKNFLEQAAASNLPEFLKALSEILVNTANSAVARMAAGLQLKNHLTSKDEKVSQQYQDRWHQFPSEIRELIKNNILAALGTENTRPSCAAQCVAYVAVIELPINRWPMLIQTLVNKVVSEGSSEMHRESALEAIGYICQDIRFGVMENQSNDVLTAIIHGMRKVEPSNHVRLAATTALHNSLEFTKSNFEKDMERNFIMEVVCEATQCQDSQICVAALQCLVKIMTLYYQYMEPYMAQALFPITLAAMKSDNDAVALQGIEFWSNVCDEEIDLAIESQEATDQGRAPQRVSKHY...
chorion-containing eggshell formation mitotic cell cycle NLS-bearing protein import into nucleus protein import into nucleus regulation of nucleocytoplasmic transport cytoplasm; nuclear envelope; nucleoplasm; nucleus; P granule nuclear import signal receptor activity nuclear localization sequence binding small GTPase b...
acyl-CoA metabolic process androgen metabolic process ecdysone metabolic process estrogen metabolic process fatty acid metabolic process mitochondrial tRNA processing steroid metabolic process
mitochondrial ribonuclease P complex; mitochondrion
3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity 3-hydroxyacyl-CoA dehydrogenase activity 7-beta-hydroxysteroid dehydrogenase (NADP+) activity acetoacetyl-CoA reductase activity dihydrotestosterone 17-beta-dehydrogenase activity estradiol 17-beta-dehydrogenase activity isoursodeoxycholate 7-beta-dehydrogenase (NAD...
Drosophila melanogaster
Mitochondrion NAD Oxidoreductase Reference proteome tRNA processing
MIKNAVSLVT
MIKNAVSLVTGGASGLGRATAERLAKQGASVILADLPSSKGNEVAKELGDKVVFVPVDVTSEKDVSAALQTAKDKFGRLDLTVNCAGTATAVKTFNFNKNVAHRLEDFQRVININTVGTFNVIRLSAGLMGANEPNQDGQRGVIVNTASVAAFDGQIGQAAYSASKAAVVGMTLPIARDLSTQGIRICTIAPGLFNTPMLAALPEKVRTFLAKSIPFPQRLGEPSEYAHLVQAIYENPLLNGEVIRIDGALRMMP
acyl-CoA metabolic process androgen metabolic process ecdysone metabolic process estrogen metabolic process fatty acid metabolic process mitochondrial tRNA processing steroid metabolic process mitochondrial ribonuclease P complex; mitochondrion 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity 3-hydroxyacyl-CoA dehy...
mitochondrial fusion mitochondrion localization Nebenkern assembly positive regulation of mitochondrial fusion sperm mitochondrion organization spermatogenesis
membrane; mitochondrial envelope; mitochondrial outer membrane
GTP binding GTPase activity
Drosophila melanogaster
Coiled coil Developmental protein Differentiation GTP-binding Hydrolase Membrane Mitochondrion Mitochondrion outer membrane Nucleotide-binding Reference proteome Spermatogenesis Transmembrane Transmembrane helix
MAESDSGEST
MAESDSGESTSSVSSFISSSSSSRLSEFVDAKTELQDIYHDLSNYLSNFLTILEETVLLKDRQMLEHLCAFSSRVEAIAKVLSRDRMKVAFFGRTSNGKSAVINALLHEKILPSAMGHTTSCFCQVQANGSNETEHVKVEQEDEHMELSALSQLASAHSPGALKPSTLLQVNMAKNRCSILDYDVVLMDTPGVDVTAQLDDCLDSYCMDADVFILVLNAESTVSRVERQFFKDVASKLSRPNLFILNNRWDKASSLEPEMEQKVKDQHMERCVNLLVDELGVYSTAQEAWERIYHVSALEALHIRNGQITNPSGQTQQRY...
mitochondrial fusion mitochondrion localization Nebenkern assembly positive regulation of mitochondrial fusion sperm mitochondrion organization spermatogenesis membrane; mitochondrial envelope; mitochondrial outer membrane GTP binding GTPase activity Drosophila melanogaster Coiled coil Developmental protein Differentia...
proteasome-mediated ubiquitin-dependent protein catabolic process
cytoplasm; cytosol; nucleoplasm; nucleus; proteasome regulatory particle; proteasome regulatory particle, base subcomplex
ATP binding ATP hydrolysis activity proteasome-activating activity
Drosophila melanogaster
ATP-binding Cytoplasm Nucleotide-binding Nucleus Proteasome Reference proteome
MTVTNRMEIE
MTVTNRMEIESAYHKGEGFRSYYIQKIEELQLVVAEKHQNLRRLQAQRNELNAKVRMLREELQLLQEQGSYVGEVVKPMDKKKVLVKVHPEGKFVVDLDKNIDINDVTPNCRVALRNESYTLHKILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIKEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQKFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSSRIESGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDPALLRPGRIDRKIEFPPPN...
proteasome-mediated ubiquitin-dependent protein catabolic process cytoplasm; cytosol; nucleoplasm; nucleus; proteasome regulatory particle; proteasome regulatory particle, base subcomplex ATP binding ATP hydrolysis activity proteasome-activating activity Drosophila melanogaster ATP-binding Cytoplasm Nucleotide-binding ...
defense response to bacterium killing of cells of another organism monoatomic ion transport
extracellular region; membrane; other organism cell membrane
toxin activity
Eisenia fetida
3D-structure Antibiotic Antimicrobial Cytolysis Direct protein sequencing Disulfide bond Hemolysis Ion transport Membrane Secreted Target cell membrane Target membrane Toxin Transmembrane Transport
MSAKAAEGYE
MSAKAAEGYEQIEVDVVAVWKEGYVYENRGSTSVDQKITITKGMKNVNSETRTVTATHSIGSTISTGDAFEIGSVEVSYSHSHEESQVSMTETEVYESKVIEHTITIPPTSKFTRWQLNADVGGADIEYMYLIDEVTPIGGTQSIPQVITSRAKIIVGRQIILGKTEIRIKHAERKEYMTVVSRKSWPAATLGHSKLFKFVLYEDWGGFRIKTLNTMYSGYEYAYSSDQGGIYFDQGTDNPKQRWAINKSLPLRHGDVVTFMNKYFTRSGLCYDDGPATNVYCLDKREDKWILEVVG
defense response to bacterium killing of cells of another organism monoatomic ion transport extracellular region; membrane; other organism cell membrane toxin activity Eisenia fetida 3D-structure Antibiotic Antimicrobial Cytolysis Direct protein sequencing Disulfide bond Hemolysis Ion transport Membrane Secreted Target...
carbohydrate metabolic process N-glycan processing protein glycosylation
Golgi apparatus; Golgi membrane
calcium ion binding mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
Spodoptera frugiperda
Calcium Disulfide bond Glycoprotein Glycosidase Golgi apparatus Hydrolase Membrane Metal-binding Signal-anchor Transmembrane Transmembrane helix
MTGILPTYQR
MTGILPTYQRFVNGVPVPSISRRSFRLREKYLIVSVLLTFGIVWLGALFYLPEFKSSNSVNDSVYNVYKRIQKAGPELLMPPPLAQNDVGDFPVIGIAHHGEGGDDPHVIEDRNRLRAKIEEDMGMKVLERPQFDVAPSVSSSRGPSKPPVDAIEEPAVGNNAANKDVSPSGPKAESSDKFVAVALAPGADPEIKHKLETVKKMMLHAWYNYKLYAWGKNELKPMSKRAHLSSVFGAGELGATIVDGLDTLYLMGLNDEFREGRDWVAEHLHINEIDSDLSVFETTIRFVGGLLSCYALTGDTMFRDKAAEVGDALLPAF...
carbohydrate metabolic process N-glycan processing protein glycosylation Golgi apparatus; Golgi membrane calcium ion binding mannosyl-oligosaccharide 1,2-alpha-mannosidase activity Spodoptera frugiperda Calcium Disulfide bond Glycoprotein Glycosidase Golgi apparatus Hydrolase Membrane Metal-binding Signal-anchor Transm...
cellular response to starvation cuticle development cytoplasmic translation egg-laying behavior IRES-dependent viral translational initiation locomotory behavior muscle cell cellular homeostasis negative regulation of protein phosphorylation negative regulation of smoothened signaling pathway oogenesis positive regulat...
autophagosome; cytoplasm; cytosol; cytosolic ribosome; nucleus; ribonucleoprotein complex
protein kinase C binding protein-macromolecule adaptor activity ribosome binding structural constituent of ribosome translation regulator activity
Drosophila melanogaster
3D-structure Reference proteome Repeat Ribonucleoprotein Ribosomal protein WD repeat
MSETLQLRGT
MSETLQLRGTLIGHNGWVTQIATNPKDPDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYLNTVTVSPDGSLCTSGGKDSKALLWDLNDGKNLYTLEHNDIINALCFSPNRYWLCVAYGPSIKIWDLACKKTVEELRPEVVSPTSKADQPQCLSLAWSTDGQTLFAGYSDNTIRVWQVSVSAH
cellular response to starvation cuticle development cytoplasmic translation egg-laying behavior IRES-dependent viral translational initiation locomotory behavior muscle cell cellular homeostasis negative regulation of protein phosphorylation negative regulation of smoothened signaling pathway oogenesis positive regulat...
collagen catabolic process extracellular matrix organization proteolysis response to stimulus
extracellular matrix; extracellular space
metalloendopeptidase activity peptidase activity zinc ion binding
Canis lupus familiaris
Calcium Collagen degradation Disulfide bond Extracellular matrix Glycoprotein Hydrolase Metal-binding Metalloprotease Protease Reference proteome Repeat Secreted Signal Zinc Zymogen
MSPRQPLVLV
MSPRQPLVLVFLVLGCCSAAPRPHKPTVVVFPGDLRTNLTDKQLAEEYLFRYGYTQVAELSNDKQSLSRGLRLLQRRLALPETGELDKTTLEAMRAPRCGVPDLGKFQTFEGDLKWHHNDITYWIQNYSEDLPRDVIDDAFARAFAVWSAVTPLTFTRVYGPEADIIIQFGVREHGDGYPFDGKNGLLAHAFPPGPGIQGDAHFDDEELWTLGKGVVVPTHFGNADGAPCHFPFTFEGRSYSACTTDGRSDDTPWCSTTADYDTDRRFGFCPSEKLYAQDGNGDGKPCVFPFTFEGRSYSTCTTDGRSDGYRWCSTTADY...
collagen catabolic process extracellular matrix organization proteolysis response to stimulus extracellular matrix; extracellular space metalloendopeptidase activity peptidase activity zinc ion binding Canis lupus familiaris Calcium Collagen degradation Disulfide bond Extracellular matrix Glycoprotein Hydrolase Metal-...
regulation of phosphorylation
cytoplasm
protein serine/threonine phosphatase inhibitor activity
Sus scrofa
3D-structure Cytoplasm Direct protein sequencing Phosphoprotein Protein phosphatase inhibitor Reference proteome
MAAQRLGKRV
MAAQRLGKRVLSKLQSPSRARGPGGSPGGLQKRHARVTVKYDRRELQRRLDVEKWIDGRLEELYRGREADMPDEVNIDELLELESEEERSRKIQGLLKSCTNPTENFVQELLVKLRGLHKQPGLRQPSPSGDGSLSPRQDRARTAPP
regulation of phosphorylation cytoplasm protein serine/threonine phosphatase inhibitor activity Sus scrofa 3D-structure Cytoplasm Direct protein sequencing Phosphoprotein Protein phosphatase inhibitor Reference proteome MAAQRLGKRV MAAQRLGKRVLSKLQSPSRARGPGGSPGGLQKRHARVTVKYDRRELQRRLDVEKWIDGRLEELYRGREADMPDEVNIDELLELESEEER...
axon guidance morphogenesis of an epithelium muscle attachment nerve development
basement membrane; cytoplasm; cytoskeleton; dystroglycan complex; extracellular region; extracellular space; membrane; nucleoplasm; plasma membrane; postsynaptic membrane; sarcolemma
calcium ion binding laminin binding
Bos taurus
Cell membrane Cytoplasm Cytoskeleton Disulfide bond Glycoprotein Membrane Nucleus Phosphoprotein Postsynaptic cell membrane Reference proteome Secreted Signal Synapse Transmembrane Transmembrane helix
MRMSVGSAVP
MRMSVGSAVPLPLWGRTFLLLLSVAVTQSHWPSEPSEAVRDWENQLEASMHSALSDLHETVPTVVGIPDGTAVVGRSFRVTIPTDLIASNGEVIKVSAAGKEALPSWLHWDPQSHTLEGLPLDTDKGVHYISVSAARLGANGSHVPQTSSVFSIEVYPEDHSEPQSLRAASPDPGEVVSLVCAADEPVTVLTVILDADLTKMTPKQRIDLLRRMRGFSEVEPHNMKLVPVVNNRLFDMSAFMAGPGNAKKVVENGALLSWKLGCCLNQNSVPDIRGVEVPAREGAMSAQLGYPVVGWHIANKKPSLPKRIRRQIHATPTP...
axon guidance morphogenesis of an epithelium muscle attachment nerve development basement membrane; cytoplasm; cytoskeleton; dystroglycan complex; extracellular region; extracellular space; membrane; nucleoplasm; plasma membrane; postsynaptic membrane; sarcolemma calcium ion binding laminin binding Bos taurus Cell memb...
angiogenesis cartilage condensation cell adhesion cell migration cell-matrix adhesion chondrocyte differentiation chondrocyte proliferation DNA biosynthetic process fibroblast growth factor receptor signaling pathway integrin-mediated signaling pathway lung development negative regulation of gene expression ossificatio...
extracellular matrix; extracellular region; Golgi apparatus
heparin binding integrin binding
Bos taurus
Cell adhesion Disulfide bond DNA synthesis Extracellular matrix Heparin-binding Reference proteome Secreted Signal
MSATGLGPVR
MSATGLGPVRCAFVLLLALCSRPASSQDCSAPCQCPAGPAPRCPAGVSLVLDGCGCCRVCAKQLSELCTERDPCDPHKGLFCDFGSPANRKIGVCTAKDGAPCVFGGTVYQSGESFQSSCKYQCTCLDGSVGCVPLCSVDVRLPSPDCPFPRRVKLPGKCCEEWVCDEPKEHTVVGPALAAYRPEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNAFCRLEKQSRLCMVRPCEADLEENIKKGKKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGEVMKKSMMFI...
angiogenesis cartilage condensation cell adhesion cell migration cell-matrix adhesion chondrocyte differentiation chondrocyte proliferation DNA biosynthetic process fibroblast growth factor receptor signaling pathway integrin-mediated signaling pathway lung development negative regulation of gene expression ossificatio...
heparan sulfate proteoglycan biosynthetic process heparin biosynthetic process
Golgi apparatus; Golgi membrane
calcium ion binding heparosan-N-sulfate-glucuronate 5-epimerase activity protein homodimerization activity racemase and epimerase activity, acting on carbohydrates and derivatives
Bos taurus
Calcium Direct protein sequencing Golgi apparatus Isomerase Membrane Metal-binding Reference proteome Signal-anchor Transmembrane Transmembrane helix
MRCLAARVNY
MRCLAARVNYKTLIIICALFTLVTVLLWNKCSSDKAIQVPRHLSSGFRVDALEKKAAASESNNYVNHMAKQSEEAFPQEQQKAPPVVGGFNNNGGGRVLGLKYEEIDCLINDEHTIKGRREGNEVFLPFTWVEKYFDVYGKVVQYDGYDRFEFSHSYSKVYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYPIQIAQYGLSHYSKNLTEKPPHIEVYETAEDRDKNSKPNDWTVPKGCFMASVADKSRFTNVKQFIAPETSEGVSLQLGNTKDFIISFDLKFLTNGSVSVVLETTEKNQLFT...
heparan sulfate proteoglycan biosynthetic process heparin biosynthetic process Golgi apparatus; Golgi membrane calcium ion binding heparosan-N-sulfate-glucuronate 5-epimerase activity protein homodimerization activity racemase and epimerase activity, acting on carbohydrates and derivatives Bos taurus Calcium Direct pro...
adenine nucleotide transport cellular response to calcium ion mitochondrial ATP transmembrane transport
membrane; mitochondrial inner membrane; mitochondrion; peroxisomal membrane
adenine nucleotide transmembrane transporter activity ADP:inorganic phosphate antiporter activity ATP:inorganic phosphate antiporter activity calcium ion binding
Oryctolagus cuniculus
Acetylation Antiport Calcium Membrane Metal-binding Mitochondrion Mitochondrion inner membrane Peroxisome Reference proteome Repeat Transmembrane Transmembrane helix Transport
MLRWLRGFVL
MLRWLRGFVLPTAACQGAEPPTRYETLFQALDRNGDGVVDIRELQEGLKSLGIPLGQDAEEKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDADGTMTVDWNEWRDYFLFNPVADIEEIIRFWKHSTGIDIGDSLTIPDEFTEEERKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKVMMQVHGSKSMNIFGGFRQMIKEGGVRSLWRGNGTNVIKIAPETAVKFWVYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAVGKTG...
adenine nucleotide transport cellular response to calcium ion mitochondrial ATP transmembrane transport membrane; mitochondrial inner membrane; mitochondrion; peroxisomal membrane adenine nucleotide transmembrane transporter activity ADP:inorganic phosphate antiporter activity ATP:inorganic phosphate antiporter activit...
absorption of visible light adaptation of rhodopsin mediated signaling cellular response to light stimulus detection of temperature stimulus involved in thermoception G protein-coupled receptor signaling pathway gene expression microtubule cytoskeleton organization photoreceptor cell maintenance phototransduction podos...
cell-cell junction; Golgi apparatus; membrane; photoreceptor disc membrane; photoreceptor inner segment membrane; photoreceptor outer segment; photoreceptor outer segment membrane; plasma membrane; rod photoreceptor outer segment; sperm head plasma membrane; sperm midpiece
11-cis retinal binding G protein-coupled photoreceptor activity metal ion binding
Sus scrofa
Acetylation Cell projection Chromophore Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Metal-binding Palmitate Phosphoprotein Photoreceptor protein Receptor Reference proteome Retinal protein Sensory transduction Transducer Transmembrane Transmembrane helix Vision Zinc
MNGTEGPNFY
MNGTEGPNFYVPFSNKTGVVRSPFEYPQYYLAEPWQFSMLAAYMFMLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGLALTWVMALACAAPPLVGWSRYIPEGLQCSCGIDYYTLKPEVNNESFVIYMFVVHFSIPLVIIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVVAFLICWLPYASVAFYIFTHQGSDFGPIFMTIPAFFAKSASIYNPVIYIMMNKQFRNCMLTT...
absorption of visible light adaptation of rhodopsin mediated signaling cellular response to light stimulus detection of temperature stimulus involved in thermoception G protein-coupled receptor signaling pathway gene expression microtubule cytoskeleton organization photoreceptor cell maintenance phototransduction podos...
2-oxoglutarate metabolic process fatty acid alpha-oxidation isoprenoid metabolic process methyl-branched fatty acid metabolic process
9+0 non-motile cilium; peroxisome
ferrous iron binding L-ascorbic acid binding phytanoyl-CoA dioxygenase activity
Bos taurus
Dioxygenase Iron Metal-binding Oxidoreductase Peroxisome Reference proteome Transit peptide Vitamin C
MDRNRASARL
MDRNRASARLTVLLRHLGCRSAGTIIAHHTSGVGSLASFHPQQFQYTRENNVLSLEQRKFYEENGFLVIKNLVSDADIQRFRNEFERICRKEVKPLGLSVMRDVTITKSEYVPSEKVVSKVQDFQEDEELFRYCTLPEILKYVECFTGPNIMAMHTMLINKPPDSGKKTSRHPLHQDLHYFPFRPSNSIVCAWTAMEHIDRNNGCLVVLPGTHKGPLQPHDYPQWEGGVNIMFHGIQDYDKNNARVHLVMEKGDTVFFHPLLIHGSGRNKSQGFRKAISCHFADANCHYIDVEGTSQENIEKEVVDIVRKKYGFKDVTLK...
2-oxoglutarate metabolic process fatty acid alpha-oxidation isoprenoid metabolic process methyl-branched fatty acid metabolic process 9+0 non-motile cilium; peroxisome ferrous iron binding L-ascorbic acid binding phytanoyl-CoA dioxygenase activity Bos taurus Dioxygenase Iron Metal-binding Oxidoreductase Peroxisome Refe...
blood vessel remodeling calcium-mediated signaling cell chemotaxis immune response inflammatory response inflammatory response to wounding macrophage migration monocyte extravasation positive regulation of cytosolic calcium ion concentration positive regulation of monocyte chemotaxis positive regulation of synaptic tra...
cytoplasm; external side of plasma membrane; plasma membrane
C-C chemokine binding C-C chemokine receptor activity
Macaca mulatta
Alternative splicing Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Inflammatory response Membrane Phosphoprotein Receptor Reference proteome Sulfation Transducer Transmembrane Transmembrane helix
MLSTSRSRFI
MLSTSRSRFIRNTNGSGEEVTTFFDYDYGAPCHKFDVKQIGAQLLPPLYSLVFIFGFVGNMLVVLILINCKKLKSLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLFTGLYHIGYLGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIFTKCQEEDSVYICGPYFPRGWNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCRNEKKRHRAVRLIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTRQLDQATQVTETLGMTHCCINPIIYAFVGEKFRRYLSMFF...
blood vessel remodeling calcium-mediated signaling cell chemotaxis immune response inflammatory response inflammatory response to wounding macrophage migration monocyte extravasation positive regulation of cytosolic calcium ion concentration positive regulation of monocyte chemotaxis positive regulation of synaptic tra...
interleukin-6-mediated signaling pathway positive regulation of cell population proliferation positive regulation of tyrosine phosphorylation of STAT protein T-helper 17 cell lineage commitment vascular endothelial growth factor production
external side of plasma membrane; extracellular region; interleukin-6 receptor complex; receptor complex
interleukin-11 binding interleukin-11 receptor activity interleukin-6 binding interleukin-6 receptor activity
Sus scrofa
Cell membrane Disulfide bond Glycoprotein Immunoglobulin domain Membrane Receptor Reference proteome Repeat Secreted Signal Transmembrane Transmembrane helix
MLAVGCALLT
MLAVGCALLTALLAAPGMALAPRGCSKLEVAQDVLTSLPGASVTLTCPGGEPGDNATIHWVLRNQVTGSPDGRPAGVGRRLLLKSVQLSDSGNYSCYQDGVPAGSVRLLVDAPPEEPQLSCFRKSPLSNVGCEWRPRSPPSPTTKAVLLVRKFQNSPVEDFQEPCQYSLEAQRFFCQLAVPEGDNSFHIVTLCVANSAGSQSSTPQTFEGYGILQPDPPVNITVSAVDRNPRWLSVTWQDPPSWNSYFYRLQFELRYRAERSKTFTTWMVKELQHHCIIHDAWSGMRHVVQLRAQEEFGHGLWSEWSQEVTGIPWTESRS...
interleukin-6-mediated signaling pathway positive regulation of cell population proliferation positive regulation of tyrosine phosphorylation of STAT protein T-helper 17 cell lineage commitment vascular endothelial growth factor production external side of plasma membrane; extracellular region; interleukin-6 receptor c...
apoptotic process cellular response to cadmium ion cellular response to copper ion cellular response to diamide cellular response to heat cellular response to sodium arsenite cellular response to unfolded protein chromatin organization negative regulation of DNA-templated transcription negative regulation of gene expre...
chromosome, centromeric region; cytosol; nucleolus; nucleus; PML body
histone binding protein homodimerization activity RNA polymerase II-specific DNA-binding transcription factor binding transcription coactivator activity transcription corepressor activity
Chlorocebus aethiops
Acetylation Apoptosis Centromere Chaperone Chromatin regulator Chromosome Coiled coil Cytoplasm Isopeptide bond Nucleus Phosphoprotein Repressor Transcription Transcription regulation Ubl conjugation
MATANSIIVL
MATANSIIVLDDDDENEAAAQPGPSHPLPSTASPEAEAPSSSEPHGARGSSSSGGKKCYKLENEKLFQEFLELCKTQTADHPEVVPFLCNRQQRAHSLFLASAEFCNILSRVLSRAQSRPFKLYVYINELCTVLKGHSAKKKLNLAPVATTSNEPSGNNPPTHLSLDPTNAENTASQAPRTRGSRRQIQRLEQLLALYVAEIRRLQERELDLSELDDPDSTYLQEARLKRKLIRLFGRLCELKDCSSLTGRVIKQRIPYRGTRYPKVNRRIERLINKPGPDTFPDYGDVLRAVKKAAARHSLGLPRQQLQLMAQDAFRNV...
apoptotic process cellular response to cadmium ion cellular response to copper ion cellular response to diamide cellular response to heat cellular response to sodium arsenite cellular response to unfolded protein chromatin organization negative regulation of DNA-templated transcription negative regulation of gene expre...
fatty acid metabolic process lipopolysaccharide catabolic process
cytoplasmic vesicle; extracellular region
acyloxyacyl hydrolase activity calcium ion binding
Oryctolagus cuniculus
3D-structure Calcium Cytoplasmic vesicle Disulfide bond Glycoprotein Hydrolase Lipid metabolism Metal-binding Reference proteome Secreted Signal Zymogen
MKSPWRILVV
MKSPWRILVVSPLLLLPLHSSTSRAHDNQPGTIRSDHYTCVGCVLVVSVIEQLAQVHNSTVQASMERLCSYLPEEWVLKTACYMMVHVFGADIIKLFDKDVNADVVCHTLEFCKQEPGQPLCHLYPLPKESWKFTLEKARHIVKQSPIMKYTRSGAGICSLPFLAKICQKIKLAIKNSVPIKDVDSDKYSIFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDAHRDSNCNGIWGVDPKDGIPYEKKFCEGSQPRGIILLGDSAGAHFHIPPEWLTVSQMSVNSFLNLPTAVTNELDWPQLSGTTGFLDSASKIKENSIYL...
fatty acid metabolic process lipopolysaccharide catabolic process cytoplasmic vesicle; extracellular region acyloxyacyl hydrolase activity calcium ion binding Oryctolagus cuniculus 3D-structure Calcium Cytoplasmic vesicle Disulfide bond Glycoprotein Hydrolase Lipid metabolism Metal-binding Reference proteome Secreted S...
cellular response to dexamethasone stimulus muscle cell cellular homeostasis myoblast migration involved in skeletal muscle regeneration negative regulation of insulin receptor signaling pathway negative regulation of myoblast differentiation negative regulation of myoblast proliferation negative regulation of phosphat...
extracellular space
cytokine activity growth factor activity heparin binding identical protein binding protein homodimerization activity
Sus scrofa
Cleavage on pair of basic residues Cytokine Disulfide bond Glycoprotein Growth factor Heparin-binding Reference proteome Secreted Signal
MQKLQIYVYI
MQKLQIYVYIYLFMLIVAGPVDLNENSEQKENVEKEGLCNACMWRQNTKSSRLEAIKIQILSKLRLETAPNISKDAIRQLLPKAPPLRELIDQYDVQRDDSSDGSLEDDDYHATTETIITMPTESDLLMQVEGKPKCCFFKFSSKIQYNKVVKAQLWIYLRPVKTPTTVFVQILRLIKPMKDGTRYTGIRSLKLDMNPGTGIWQSIDVKTVLQNWLKQPESNLGIEIKALDENGHDLAVTFPGPGEDGLNPFLEVKVTDTPKRSRRDFGLDCDEHSTESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGECEFVFLQK...
cellular response to dexamethasone stimulus muscle cell cellular homeostasis myoblast migration involved in skeletal muscle regeneration negative regulation of insulin receptor signaling pathway negative regulation of myoblast differentiation negative regulation of myoblast proliferation negative regulation of phosphat...
cellular response to dexamethasone stimulus muscle cell cellular homeostasis myoblast migration involved in skeletal muscle regeneration negative regulation of fibroblast proliferation negative regulation of insulin receptor signaling pathway negative regulation of myoblast differentiation negative regulation of phosph...
extracellular space
cytokine activity growth factor activity heparin binding identical protein binding protein homodimerization activity
Bos taurus
Cleavage on pair of basic residues Cytokine Disease variant Disulfide bond Glycoprotein Growth factor Heparin-binding Reference proteome Secreted Signal
MQKLQISVYI
MQKLQISVYIYLFMLIVAGPVDLNENSEQKENVEKEGLCNACLWRENTTSSRLEAIKIQILSKLRLETAPNISKDAIRQLLPKAPPLLELIDQFDVQRDASSDGSLEDDDYHARTETVITMPTESDLLTQVEGKPKCCFFKFSSKIQYNKLVKAQLWIYLRPVKTPATVFVQILRLIKPMKDGTRYTGIRSLKLDMNPGTGIWQSIDVKTVLQNWLKQPESNLGIEIKALDENGHDLAVTFPEPGEDGLTPFLEVKVTDTPKRSRRDFGLDCDEHSTESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGECEFVFLQK...
cellular response to dexamethasone stimulus muscle cell cellular homeostasis myoblast migration involved in skeletal muscle regeneration negative regulation of fibroblast proliferation negative regulation of insulin receptor signaling pathway negative regulation of myoblast differentiation negative regulation of phosph...
cardiac muscle cell action potential involved in contraction magnesium ion transport potassium ion import across plasma membrane potassium ion transport protein homotetramerization regulation of heart rate by cardiac conduction regulation of membrane repolarization regulation of monoatomic ion transmembrane transport r...
membrane; plasma membrane; voltage-gated potassium channel complex
identical protein binding inward rectifier potassium channel activity phosphatidylinositol-4,5-bisphosphate binding voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization
Sus scrofa
Ion channel Ion transport Lipoprotein Membrane Myristate Potassium Potassium transport Reference proteome S-nitrosylation Transmembrane Transmembrane helix Transport Voltage-gated channel
MGSVRTNRYS
MGSVRTNRYSIVSSEEDGMKLATLAVANGFGNGKSKVHTRQQCRSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLDASKESKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEI...
cardiac muscle cell action potential involved in contraction magnesium ion transport potassium ion import across plasma membrane potassium ion transport protein homotetramerization regulation of heart rate by cardiac conduction regulation of membrane repolarization regulation of monoatomic ion transmembrane transport r...
axonogenesis cell motility
actin cytoskeleton; actin filament; axon; cytoplasm; cytoskeleton; dense body; focal adhesion; membrane; NuA4 histone acetyltransferase complex; nucleus; plasma membrane; protein-containing complex; synapse
ATP binding hydrolase activity protein kinase binding structural constituent of postsynaptic actin cytoskeleton
Canis lupus familiaris
Acetylation ATP-binding Cytoplasm Cytoskeleton Hydrolase Methylation Nucleotide-binding Nucleus Oxidation Reference proteome Ubl conjugation
MDDDIAALVV
MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITAL...
axonogenesis cell motility actin cytoskeleton; actin filament; axon; cytoplasm; cytoskeleton; dense body; focal adhesion; membrane; NuA4 histone acetyltransferase complex; nucleus; plasma membrane; protein-containing complex; synapse ATP binding hydrolase activity protein kinase binding structural constituent of postsy...
action potential cellular response to glucose stimulus cellular response to nutrient levels glucose homeostasis glutamate receptor signaling pathway negative regulation of insulin secretion positive regulation of calcium ion-dependent exocytosis positive regulation of catecholamine secretion positive regulation of long...
axon; dendrite; dendrite membrane; lateral plasma membrane; neuronal cell body membrane; perikaryon; plasma membrane; postsynaptic membrane; sarcolemma; voltage-gated potassium channel complex
delayed rectifier potassium channel activity protein heterodimerization activity
Sus scrofa
Cell membrane Cell projection Exocytosis Ion channel Ion transport Isopeptide bond Membrane Phosphoprotein Postsynaptic cell membrane Potassium Potassium channel Potassium transport Reference proteome Synapse Synaptosome Transmembrane Transmembrane helix Transport Ubl conjugation Voltage-gated channel
MPAGMTKHGS
MPAGMTKHGSRSTSSLPPEPMEIVRSKACSRRVRLNVGGLAHEVLWRTLDRLPRTRLGKLRDCNTHDSLLEVCDDYSLDDNEYFFDRHPGAFTSILNFYRTGRLHMMEEMCALSFSQELDYWGIDEIYLESCCQARYHQKKEQMNEELKREAETLREREGEEFDNTCCAEKRKKLWDLLEKPNSSVAAKILAIISIMFIVLSTIALSLNTLPELQSLDEFGQTTDNPQLAHVEAVCIAWFTMEYLLRFLSSPKKWKFFKGPLNAIDLLAILPYYVTIFLTESNKSVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSL...
action potential cellular response to glucose stimulus cellular response to nutrient levels glucose homeostasis glutamate receptor signaling pathway negative regulation of insulin secretion positive regulation of calcium ion-dependent exocytosis positive regulation of catecholamine secretion positive regulation of long...
cell differentiation cellular response to insulin stimulus fatty acid metabolic process hormone-mediated signaling pathway macrophage derived foam cell differentiation negative regulation of cholesterol storage negative regulation of inflammatory response negative regulation of transcription by RNA polymerase II positi...
cytoplasm; nucleoplasm
chromatin binding DNA-binding transcription factor activity DNA-binding transcription repressor activity, RNA polymerase II-specific E-box binding nuclear receptor activity RNA polymerase II cis-regulatory region sequence-specific DNA binding transcription cis-regulatory region binding zinc ion binding
Macaca mulatta
Activator Alternative splicing Biological rhythms Cytoplasm DNA-binding Glycoprotein Metal-binding Nucleus Phosphoprotein Receptor Reference proteome Transcription Transcription regulation Zinc Zinc-finger
MGETLGDSPI
MGETLGDSPIDPESDSFTDTLSANISQEITMVDTEMPFWPTNFGISSVDLSVMDDHSHSFDIKPFTTVDFSSISAPHYEDIPFTRTDPMVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEA...
cell differentiation cellular response to insulin stimulus fatty acid metabolic process hormone-mediated signaling pathway macrophage derived foam cell differentiation negative regulation of cholesterol storage negative regulation of inflammatory response negative regulation of transcription by RNA polymerase II positi...
bone morphogenesis collagen catabolic process extracellular matrix disassembly extracellular matrix organization proteolysis
extracellular matrix; extracellular space
calcium ion binding collagen binding endopeptidase activity metalloendopeptidase activity zinc ion binding
Equus caballus
Calcium Collagen degradation Disulfide bond Extracellular matrix Glycoprotein Hydrolase Metal-binding Metalloprotease Phosphoprotein Protease Reference proteome Repeat Secreted Signal Zinc Zymogen
MHPGVLAAFL
MHPGVLAAFLFLSWTRCWSLPVPNDDDDDDDMSEEDFQLAERYLKSYYYPLNPAGILKKTAANSVVDRLREMQSFFGLEVTGKLDDNTLDIMKKPRCGVPDVGEYNVFPRTLKWPKMNLTYRIVNYTPDLTHSEVEKAFKKAFKVWSDVTPLNFTRLYNGTADIMISFGTKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFVLPDDDVQGIQYLYGPGDEDPNPKHPKTPDKCDPSLSLDAITSLRGETMVFKDRFFWRLHPQLVDAE...
bone morphogenesis collagen catabolic process extracellular matrix disassembly extracellular matrix organization proteolysis extracellular matrix; extracellular space calcium ion binding collagen binding endopeptidase activity metalloendopeptidase activity zinc ion binding Equus caballus Calcium Collagen degradation Di...
defense response to virus
lysosome
lyase activity nucleic acid binding ribonuclease A activity
Aotus trivirgatus
Disulfide bond Endonuclease Glycoprotein Hydrolase Lyase Lysosome Nitration Nuclease Signal
MVPKLFTSQI
MVPKLFTSQICLLLLLGLLGVEGSLHAAPQKFTRAQWFSIQHIQTTPLRCTNAMRAINKYQHRCKNQNTFLHTTFAAVVNVCGNTNITCPRNASLNNCHHSRVQVPLTYCNLTGPPTITNCVYSSTQANMFYVVACDNRDQRDPPQYPVVPVHLDTTI
defense response to virus lysosome lyase activity nucleic acid binding ribonuclease A activity Aotus trivirgatus Disulfide bond Endonuclease Glycoprotein Hydrolase Lyase Lysosome Nitration Nuclease Signal MVPKLFTSQI MVPKLFTSQICLLLLLGLLGVEGSLHAAPQKFTRAQWFSIQHIQTTPLRCTNAMRAINKYQHRCKNQNTFLHTTFAAVVNVCGNTNITCPRNASLNNCHHSRV...
nucleoside diphosphate catabolic process platelet aggregation
caveola; plasma membrane
ADP phosphatase activity apyrase activity ATP binding ATP hydrolysis activity CDP phosphatase activity CTPase activity GDP phosphatase activity GTPase activity IDP phosphatase activity ITPase activity nucleoside diphosphate phosphatase activity ribonucleoside triphosphate phosphatase activity UDP phosphatase activity
Bos taurus
ATP-binding Calcium Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Magnesium Membrane Nucleotide-binding Reference proteome Transmembrane Transmembrane helix
MEDRRESELK
MEDRRESELKVFCSKNILSILGFSCIIAVIALLALGLTQNKALPENVKFGIVLDAGSSHTSLYIYRWPAEKENDTGVVTQIEESNVKGPGISGFAKKVNEINVYLTACMERAQKVIPSIQHMETPVYLGATAGMRLLRMENKQMADKILAAVASSISEYPFDFQGARIISGQEEGAYGWITVNYLLGKFTQKLSWFNLKPSKDDTQETYGALDLGGASTQITFVPQNETTESPNNNLYFRLYGKNYSVYTHSFLCYGKDQALLQKLALGLQGTNGIIHEPCFHSRYMRKIKMSVLNEGFCTKRHELNSSFYPLVDIEIRG...
nucleoside diphosphate catabolic process platelet aggregation caveola; plasma membrane ADP phosphatase activity apyrase activity ATP binding ATP hydrolysis activity CDP phosphatase activity CTPase activity GDP phosphatase activity GTPase activity IDP phosphatase activity ITPase activity nucleoside diphosphate phosphata...
epoxygenase P450 pathway xenobiotic metabolic process
cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; mitochondrial inner membrane
arachidonic acid epoxygenase activity aromatase activity heme binding Hsp70 protein binding Hsp90 protein binding iron ion binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
Bos taurus
Endoplasmic reticulum Fatty acid metabolism Heme Iron Lipid metabolism Membrane Metal-binding Microsome Mitochondrion Mitochondrion inner membrane Monooxygenase NADP Oxidoreductase Reference proteome
MAALGITVAL
MAALGITVALLVWMATLLFISIWKHIYSSWKLPPGPFPLPIIGNLLQLDIKNIPKSFTRLAERYGPVFTLYLGSQRAVVVHGYKPVKEVLLDYKNEFSGRGENPGFQMHKNNGIIFNNGSTWRDTRRFSLTTLRDLGMGKQGNEQRIQREAHFLLEVLRKTQGQPFDPTFVVGFAPYNVISDILFHKRFDYKDQTSLRLMSLFNENFYLLSSPWIQLYNNFPDYLQYLPGSHRKLLKNVSEVKSYALERVKDHQKSLEPSCPRGFLDTMLIEMAKERHSVDPMYTLENIAVTVADLLFAGTETTSTTLRYGLLILMKYPE...
epoxygenase P450 pathway xenobiotic metabolic process cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; mitochondrial inner membrane arachidonic acid epoxygenase activity aromatase activity heme binding Hsp70 protein binding Hsp90 protein binding iron ion binding oxidoreductase activi...
cellular response to calcium ion potassium ion transmembrane transport regulation of cell population proliferation regulation of membrane potential
axon; dendrite; early endosome membrane; nuclear inner membrane; perikaryon; plasma membrane; postsynaptic density membrane; presynaptic membrane; voltage-gated potassium channel complex
calmodulin binding delayed rectifier potassium channel activity phosphatidylinositol bisphosphate binding voltage-gated potassium channel activity
Bos taurus
Alternative splicing Calmodulin-binding Cell membrane Cell projection Endosome Glycoprotein Ion channel Ion transport Lipid-binding Membrane Nucleus Phosphoprotein Postsynaptic cell membrane Potassium Potassium channel Potassium transport Reference proteome Synapse Transmembrane Transmembrane helix Transport Voltage-ga...
MTMAGGRKGL
MTMAGGRKGLVAPQNTFLENIVRRSNDTNFVLGNAQIVDWPIVYSNDGFCKLSGYHRAEVMQKSSTCSFMYGELTDKDTIEKVRQTFENYEMNSFEILMYKKNRTPVWFFVKIAPIRNEQDKVVLFLCTFSDITAFKQPIEDDSCKGWGKFARLTRALTSSRGVLQQLAPSVQKGENVHKHSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCVFKTTWDWIILILTFYTAILVPYNVSFKTRQNNVAWLVVDSIVDVIFLVDIVLNFHTTFVGPAGEVISDPKLIRMNYLKTWFVIDLLSCLPYDVINAFENVDEVSA...
cellular response to calcium ion potassium ion transmembrane transport regulation of cell population proliferation regulation of membrane potential axon; dendrite; early endosome membrane; nuclear inner membrane; perikaryon; plasma membrane; postsynaptic density membrane; presynaptic membrane; voltage-gated potassium c...
cell differentiation cell fate commitment cellular response to insulin stimulus epithelial cell differentiation fatty acid metabolic process hormone-mediated signaling pathway macrophage derived foam cell differentiation negative regulation of cholesterol storage negative regulation of DNA-templated transcription negat...
cytoplasm; nucleus
chromatin binding DNA binding DNA-binding transcription factor activity DNA-binding transcription repressor activity, RNA polymerase II-specific E-box binding nuclear receptor activity RNA polymerase II cis-regulatory region sequence-specific DNA binding transcription cis-regulatory region binding zinc ion binding
Bos taurus
Activator Alternative splicing Biological rhythms Cytoplasm DNA-binding Metal-binding Nucleus Phosphoprotein Receptor Reference proteome Transcription Transcription regulation Zinc Zinc-finger
MGETLGDALI
MGETLGDALIDPESEPFAVTVSARTSQEITMVDTEMPFWPTNFGISSVDLSMMDDHSHAFDIKPFTTVDFSSISTPHYEDIPFPRADPMVADYKYDLKLQEYQSAIKVEPVSPPYYSEKTQLYSKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHISPLQEPSKEVAIRIFQGCQFRSVEA...
cell differentiation cell fate commitment cellular response to insulin stimulus epithelial cell differentiation fatty acid metabolic process hormone-mediated signaling pathway macrophage derived foam cell differentiation negative regulation of cholesterol storage negative regulation of DNA-templated transcription negat...
endocytosis protein transport
cytosol; early endosome; endocytic vesicle; recycling endosome
DNA binding guanyl-nucleotide exchange factor activity small GTPase binding zinc ion binding
Bos taurus
3D-structure Acetylation Coiled coil Cytoplasm Direct protein sequencing Endocytosis Endosome Metal-binding Phosphoprotein Protein transport Reference proteome Transport Ubl conjugation Ubl conjugation pathway Zinc Zinc-finger
MSLKSERRGI
MSLKSERRGIHVDQSELLCKKGCGYYGNPAWQGFCSKCWREEYHKARQKQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKTRKVTTVKKFFSASSRVGAKKAEIQEAKAPSPSINRQTSIETDRVSKEFIEFLKTFHKTGQEIYKQTKLFLEAMHYKRDLSIEEQSECTQDFYQNVAERMQTRGKVPPERVEKIMDQIEKYIMTRLYKYVFCPETTDDEKKDLAIQKRIRALHWVTPQMLCVPVNEEIPEVSDMVVKAITDIIEMDSKRVPRDKLACITKCSKHIFNAIKITKNEPASADDFLPTL...
endocytosis protein transport cytosol; early endosome; endocytic vesicle; recycling endosome DNA binding guanyl-nucleotide exchange factor activity small GTPase binding zinc ion binding Bos taurus 3D-structure Acetylation Coiled coil Cytoplasm Direct protein sequencing Endocytosis Endosome Metal-binding Phosphoprotein ...
apoptotic process DNA catabolic process neutrophil activation involved in immune response regulation of acute inflammatory response regulation of neutrophil mediated cytotoxicity
extracellular region; nuclear envelope; zymogen granule
actin binding deoxyribonuclease I activity
Oryctolagus cuniculus
Actin-binding Apoptosis Calcium Cytoplasmic vesicle Direct protein sequencing Disulfide bond Endonuclease Glycoprotein Hydrolase Nuclease Nucleus Reference proteome Secreted Signal
MRSEMLTALL
MRSEMLTALLTLAVLLQVAGSLKIAAFNIRSFGETKMSNATLTSYIVRILQRYDIALIQEVRDSHLTAVGKLLDKLNEKAADTYRFVASEPLGRRTYKERYLFVYRPDQVSVLDSYYYDDGCEPCGTDTFSREPAVVRFSSPSTKVREFAIVPLHSAPEDAVAEIDALYDVYLDVQKKWGLQDVMLMGDFNADYSYVTSSQWSSIRLRTNPAFKWLIPDTADTTATSTNCAYDRIVVAGPLLQDAVVPNSAAPFNFQAAYGLSNQLAQAISDHYPVEVTLA
apoptotic process DNA catabolic process neutrophil activation involved in immune response regulation of acute inflammatory response regulation of neutrophil mediated cytotoxicity extracellular region; nuclear envelope; zymogen granule actin binding deoxyribonuclease I activity Oryctolagus cuniculus Actin-binding Apopto...
blood coagulation proteolysis
extracellular region
calcium ion binding serine-type endopeptidase activity
Oryctolagus cuniculus
Blood coagulation Calcium Cleavage on pair of basic residues Disulfide bond EGF-like domain Gamma-carboxyglutamic acid Glycoprotein Hemostasis Hydrolase Hydroxylation Protease Reference proteome Repeat Secreted Serine protease Signal Zymogen
MANPLHLVLL
MANPLHLVLLGAALAGLLLSGSSVFISRRAANDVLARTRRANSFLEELKKGNLERECMEENCSYEEALEVFEDREKTNEFWNKYVDGDQCESNPCQNQGTCKDGLGMYTCSCVEGYEGQDCEPVTRKLCSLDNGGCDQFCKEEENSVLCSCASGYTLGDNGKSCISTELFPCGKVTLGRWRRSPATNSSEGPPEAPGPEQQDDGNLTATENPFNLLDSPEPPPEDDSSSLVRIVGGQDCRDGECPWQALLVNEENEGFCGGTILSEYHVLTAAHCLHQAKRFKVRVGDRDTEHEEGNEETHEVEVVVKHNRFVKETYDFD...
blood coagulation proteolysis extracellular region calcium ion binding serine-type endopeptidase activity Oryctolagus cuniculus Blood coagulation Calcium Cleavage on pair of basic residues Disulfide bond EGF-like domain Gamma-carboxyglutamic acid Glycoprotein Hemostasis Hydrolase Hydroxylation Protease Reference proteo...
cellular response to insulin stimulus macrophage derived foam cell differentiation positive regulation of DNA-templated transcription positive regulation of fat cell differentiation positive regulation of transcription by RNA polymerase II regulation of circadian rhythm regulation of DNA-templated transcription regulat...
cytoplasm; nucleus
chromatin binding DNA-binding transcription factor activity E-box binding nuclear receptor activity transcription cis-regulatory region binding zinc ion binding
Oryctolagus cuniculus
Activator Biological rhythms Cytoplasm DNA-binding Metal-binding Nucleus Phosphoprotein Receptor Reference proteome Transcription Transcription regulation Zinc Zinc-finger
MVDTEMPFWP
MVDTEMPFWPTNFGIGSVDLSVMDDHSHSFDIKPFTTVDFSSISAPHYEDLPFARADPMVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKTHEEPSNSLMAIECRVCSDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKNIPGFVSLDLNDQVTLLKYGV...
cellular response to insulin stimulus macrophage derived foam cell differentiation positive regulation of DNA-templated transcription positive regulation of fat cell differentiation positive regulation of transcription by RNA polymerase II regulation of circadian rhythm regulation of DNA-templated transcription regulat...
ethanol oxidation fatty acid omega-oxidation
cytoplasm
alcohol dehydrogenase (NAD+) activity S-(hydroxymethyl)glutathione dehydrogenase NAD activity S-(hydroxymethyl)glutathione dehydrogenase NADP activity zinc ion binding
Oryctolagus cuniculus
Acetylation Cytoplasm Lipid metabolism Metal-binding NAD Oxidoreductase Phosphoprotein Reference proteome Zinc
MANKVIKCKA
MANKVIKCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKIFATAVCHTDAYTLSGADPEGCFPVILGHEGAGIVESVGEGVTNLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGKGLMPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPSAPLDKVCLLGCGISTGYGAALNTAKVEPGSTCAVFGLGGVGLAAIMGCKAAGASRIIAVDINKDKFARAKEFGATECINPQDFSKPIQEVLVEKTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAGAGEEISTRPFQLVTGRTWKGTAFG...
ethanol oxidation fatty acid omega-oxidation cytoplasm alcohol dehydrogenase (NAD+) activity S-(hydroxymethyl)glutathione dehydrogenase NAD activity S-(hydroxymethyl)glutathione dehydrogenase NADP activity zinc ion binding Oryctolagus cuniculus Acetylation Cytoplasm Lipid metabolism Metal-binding NAD Oxidoreductase Pho...