Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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heme catabolic process heme oxidation response to hypoxia response to oxidative stress | endoplasmic reticulum membrane; plasma membrane | heme binding heme oxygenase (decyclizing) activity metal ion binding | Mus musculus | Acetylation Endoplasmic reticulum Heme Iron Membrane Metal-binding Microsome Oxidoreductase Phosphoprotein Reference proteome Repeat Transmembrane Transmembrane helix | MSSEVETSEG | MSSEVETSEGVDESEKNSMAPEKENHTKMADLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKELFKLATTALYFTYSALEEEMDRNKDHPAFAPLYFPTELHRKAALIKDMKYFFGENWEEQVKCSEAAQKYVDRIHYVGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFEHVDNAQQFKQFYRARMNALDLNLKTKERIVEEANKAFEYNMQIFSELDQAGSMLARETLEDGLPVHDGKGDIRKCPFYAAQPDKGTLGGSNCPFQTTVAVLRKPSLQLILAASVALVAGLLAWYYM | heme catabolic process heme oxidation response to hypoxia response to oxidative stress endoplasmic reticulum membrane; plasma membrane heme binding heme oxygenase (decyclizing) activity metal ion binding Mus musculus Acetylation Endoplasmic reticulum Heme Iron Membrane Metal-binding Microsome Oxidoreductase Phosphoprotein Reference proteome Repeat Transmembrane Transmembrane helix MSSEVETSEG MSSEVETSEGVDESEKNSMAPEKENHTKMADLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKELFKLATTALYFTYSALEEEMDRNKDHPAFAPLYFPTELHRKAALIKDMKYFFGENWEEQVKCSEAAQKYVDRIHYVGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFEHVDNAQQFKQFYRARMNALDLNLKTKERIVEEANKAFEYNMQIFSELDQAGSMLARETLEDGLPVHDGKGDIRKCPFYAAQPDKGTLGGSNCPFQTTVAVLRKPSLQLILAASVALVAGLLAWYYM |
endosome to lysosome transport intracellular protein transport organelle assembly organelle localization positive regulation of receptor localization to synapse positive regulation of T cell mediated cytotoxicity regulation of protein localization to plasma membrane synaptic vesicle exocytosis vesicle docking vesicle fusion vesicle-mediated transport | azurophil granule; early endosome; early endosome membrane; endocytic vesicle; endomembrane system; endosome; immunological synapse; late endosome; late endosome membrane; lysosomal membrane; lysosome; perinuclear region of cytoplasm; plasma membrane; recycling endosome; SNARE complex; synaptic vesicle; synaptic vesicle membrane; terminal bouton; tertiary granule; vesicle | chloride channel inhibitor activity protein-containing complex binding SNAP receptor activity SNARE binding syntaxin binding | Rattus norvegicus | Acetylation Coiled coil Endosome Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix | MSYTPGIGGD | MSYTPGIGGDPAQLAQRISSNIQKITQCSAEIQRTLNQLGTPQDTPELRQQLQQEQQYTNQLAKETDKYIKEFGFLPTTPSEQRQRKIQKDRLVAEFTTALTNFQKVQRQAAEREKEFVARVRASSRVSGGFPEDSSKEKNFVSWESQTQPQVQVQDEEITEDDLRLIHERESSIRQLEADIMDINEIFKDLGMMIHEQGDVIDSIEANVESAEVHVQQANQQLSRAANYQRKSRKTLCIIILILVVGIVIIFFIVWGLKG | endosome to lysosome transport intracellular protein transport organelle assembly organelle localization positive regulation of receptor localization to synapse positive regulation of T cell mediated cytotoxicity regulation of protein localization to plasma membrane synaptic vesicle exocytosis vesicle docking vesicle fusion vesicle-mediated transport azurophil granule; early endosome; early endosome membrane; endocytic vesicle; endomembrane system; endosome; immunological synapse; late endosome; late endosome membrane; lysosomal membrane; lysosome; perinuclear region of cytoplasm; plasma membrane; recycling endosome; SNARE complex; synaptic vesicle; synaptic vesicle membrane; terminal bouton; tertiary granule; vesicle chloride channel inhibitor activity protein-containing complex binding SNAP receptor activity SNARE binding syntaxin binding Rattus norvegicus Acetylation Coiled coil Endosome Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix MSYTPGIGGD MSYTPGIGGDPAQLAQRISSNIQKITQCSAEIQRTLNQLGTPQDTPELRQQLQQEQQYTNQLAKETDKYIKEFGFLPTTPSEQRQRKIQKDRLVAEFTTALTNFQKVQRQAAEREKEFVARVRASSRVSGGFPEDSSKEKNFVSWESQTQPQVQVQDEEITEDDLRLIHERESSIRQLEADIMDINEIFKDLGMMIHEQGDVIDSIEANVESAEVHVQQANQQLSRAANYQRKSRKTLCIIILILVVGIVIIFFIVWGLKG |
negative regulation of DNA-templated transcription negative regulation of gene expression negative regulation of osteoclast differentiation negative regulation of protein sumoylation negative regulation of transcription by RNA polymerase II positive regulation of gene expression positive regulation of membrane potential positive regulation of protein sumoylation protein sumoylation regulation of transcription by RNA polymerase II response to hormone TNFSF11-mediated signaling pathway | cytoplasm; dendrite; nuclear speck; nucleus | ionotropic glutamate receptor binding NF-kappaB binding potassium channel regulator activity SUMO ligase activity SUMO transferase activity transcription coregulator activity transmembrane transporter binding zinc ion binding | Rattus norvegicus | Cytoplasm Isopeptide bond Metal-binding Nucleus Reference proteome Transcription Transcription regulation Transferase Ubl conjugation Ubl conjugation pathway Zinc Zinc-finger | MAELGELKHM | MAELGELKHMVMSFRVSELQVLLGFAGRNKSGRKHELLAKALHLLKSSCAPSVQMKIKELYRRRFPRKTLGPSDLSLLSLPPGTSPVGSPSPLASIPPTLLTPGTLLGPKREVDMHPPLPQPVHPDVTMKPLPFYEVYGELIRPTTLASTSSQRFEEAHFTFALTPQQLQQILTSREVLPGAKCDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYLPPTKNGAEPKRPSRPINITPLARLSATVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHLQSFDAALYLQMNEKKPTWTCPVCDKKAPYESLIIDGLFMEILNSCSDCDEIQFMEDGSWCPMKPKKEASEVCPPPGYGLDGLQYSPVQEGNQSENKKRVEVIDLTIESSSDEEDLPPTKKHCPVTSAAIPALPGSKGALTSGHQPSSVLRSPAMGTLGSDFLSSLPLHEYPPAFPLGADIQGLDLFSFLQTESQHYSPSVITSLDEQDTLGHFFQFRGTPPHFLGPLAPTLGSSHRSATPAPAPGRVSSIVAPGSSLREGHGGPLPSGPSLTGCRSDVISLD | negative regulation of DNA-templated transcription negative regulation of gene expression negative regulation of osteoclast differentiation negative regulation of protein sumoylation negative regulation of transcription by RNA polymerase II positive regulation of gene expression positive regulation of membrane potential positive regulation of protein sumoylation protein sumoylation regulation of transcription by RNA polymerase II response to hormone TNFSF11-mediated signaling pathway cytoplasm; dendrite; nuclear speck; nucleus ionotropic glutamate receptor binding NF-kappaB binding potassium channel regulator activity SUMO ligase activity SUMO transferase activity transcription coregulator activity transmembrane transporter binding zinc ion binding Rattus norvegicus Cytoplasm Isopeptide bond Metal-binding Nucleus Reference proteome Transcription Transcription regulation Transferase Ubl conjugation Ubl conjugation pathway Zinc Zinc-finger MAELGELKHM MAELGELKHMVMSFRVSELQVLLGFAGRNKSGRKHELLAKALHLLKSSCAPSVQMKIKELYRRRFPRKTLGPSDLSLLSLPPGTSPVGSPSPLASIPPTLLTPGTLLGPKREVDMHPPLPQPVHPDVTMKPLPFYEVYGELIRPTTLASTSSQRFEEAHFTFALTPQQLQQILTSREVLPGAKCDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYLPPTKNGAEPKRPSRPINITPLARLSATVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHLQSFDAALYLQMNEKKPTWTCPVCDKKAPYESLIIDGLFMEILNSCSDCDEIQFMEDGSWCPMKPKKEASEVCPPPGYGLDGLQYSPVQEGNQSENKKRVEVIDLTIESSSDEEDLPPTKKHCPVTSAAIPALPGSKGALTSGHQPSSVLRSPAMGTLGSDFLSSLPLHEYPPAFPLGADIQGLDLFSFLQTESQHYSPSVITSLDEQDTLGHFFQFRGTPPHFLGPLAPTLGSSHRSATPAPAPGRVSSIVAPGSSLREGHGGPLPSGPSLTGCRSDVISLD |
protein ubiquitination ubiquitin-dependent protein catabolic process | cytoplasm | identical protein binding metal ion binding PDZ domain binding ubiquitin-protein transferase activity | Mus musculus | 3D-structure Alternative splicing Cytoplasm Metal-binding Phosphoprotein Reference proteome Repeat Transferase Ubl conjugation pathway Zinc Zinc-finger | MNQPDLADDP | MNQPDLADDPDPSPEPLCIVCGQNHSPEENHFYTYTEDVDDDLICHICLQALLDPLDTPCGHTYCTLCLTNFLVEKDFCPVDRKPVVLQHCKKSSILVNKLLNKLLVTCPFTEHCTEVLQRCDLQHHFQTSCKGASHYGLTKDRKRRSQDGCPDGCASLMATTLSPEVSAAATISLMTDEPGLDNPAYVSSVEDGEPVANSSDSGRSNRTRARPFERSTMRSRSFKKINRALSALRRTKSGSVVANHVDQGRDNSENTTVPEVFPRLFHLIPDGEITSIKINRADPSESLSIRLVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDIILKVNGMDISNVPHNYAVRLLRQPCQVLRLTVLREQKFRSRSNAHVPDSYGPRDDSFHVILNKSSPEEQLGIKLVRRVDEPGVFIFNVLNGGVADRHGQLEENDRVLAINGHDLRFGSPESAAHLIQASERRVHLVVSRQVRQSSPDIFQEAGWISNGQQSPGPGERNTASKPAATCHEKVVSVWKDPSESLGMTVGGGASHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVNGIELTEVSRTEAVAILKSAPSSVVLKALEVKEQEAQEDCSPAALDSNHNVTPPGDWSPSWVMWLELPQYLCNCKDVILRRNTAGSLGFCIVGGYEEYSGNKPFFIKSIVEGTPAYNDGRIRCGDILLAVNGRSTSGMIHACLARMLKELKGRITLTIASWPGTFL | protein ubiquitination ubiquitin-dependent protein catabolic process cytoplasm identical protein binding metal ion binding PDZ domain binding ubiquitin-protein transferase activity Mus musculus 3D-structure Alternative splicing Cytoplasm Metal-binding Phosphoprotein Reference proteome Repeat Transferase Ubl conjugation pathway Zinc Zinc-finger MNQPDLADDP MNQPDLADDPDPSPEPLCIVCGQNHSPEENHFYTYTEDVDDDLICHICLQALLDPLDTPCGHTYCTLCLTNFLVEKDFCPVDRKPVVLQHCKKSSILVNKLLNKLLVTCPFTEHCTEVLQRCDLQHHFQTSCKGASHYGLTKDRKRRSQDGCPDGCASLMATTLSPEVSAAATISLMTDEPGLDNPAYVSSVEDGEPVANSSDSGRSNRTRARPFERSTMRSRSFKKINRALSALRRTKSGSVVANHVDQGRDNSENTTVPEVFPRLFHLIPDGEITSIKINRADPSESLSIRLVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDIILKVNGMDISNVPHNYAVRLLRQPCQVLRLTVLREQKFRSRSNAHVPDSYGPRDDSFHVILNKSSPEEQLGIKLVRRVDEPGVFIFNVLNGGVADRHGQLEENDRVLAINGHDLRFGSPESAAHLIQASERRVHLVVSRQVRQSSPDIFQEAGWISNGQQSPGPGERNTASKPAATCHEKVVSVWKDPSESLGMTVGGGASHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVNGIELTEVSRTEAVAILKSAPSSVVLKALEVKEQEAQEDCSPAALDSNHNVTPPGDWSPSWVMWLELPQYLCNCKDVILRRNTAGSLGFCIVGGYEEYSGNKPFFIKSIVEGTPAYNDGRIRCGDILLAVNGRSTSGMIHACLARMLKELKGRITLTIASWPGTFL |
dephosphorylation | cytoplasm; early endosome; nucleus; plasma membrane | protein tyrosine phosphatase activity | Mus musculus | 3D-structure Cell membrane Cytoplasm Disulfide bond Endosome Hydrolase Lipoprotein Membrane Methylation Prenylation Protein phosphatase Reference proteome | MNRPAPVEIS | MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALIECGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGHCCVQ | dephosphorylation cytoplasm; early endosome; nucleus; plasma membrane protein tyrosine phosphatase activity Mus musculus 3D-structure Cell membrane Cytoplasm Disulfide bond Endosome Hydrolase Lipoprotein Membrane Methylation Prenylation Protein phosphatase Reference proteome MNRPAPVEIS MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALIECGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGHCCVQ |
camera-type eye development circadian rhythm detection of light stimulus involved in visual perception neural retina development response to light stimulus retina homeostasis retinal metabolic process retinoid metabolic process retinol metabolic process zeaxanthin biosynthetic process | cell body; cytoplasm; endoplasmic reticulum membrane; membrane; nucleus; plasma membrane | all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity beta-carotene 15,15'-dioxygenase activity cardiolipin binding isomerase activity metal ion binding phosphatidylcholine binding phosphatidylserine binding retinol isomerase activity | Rattus norvegicus | Acetylation Cell membrane Cytoplasm Endoplasmic reticulum Hydrolase Iron Isomerase Lipid metabolism Lipoprotein Membrane Metal-binding Microsome Palmitate Phosphoprotein Reference proteome Sensory transduction Vision | MSIQIEHPAG | MSIQIEHPAGGYKKLFETVEELSTPLTAHVTGRIPLWLTGSLLRCGPGLFEVGSEPFYHLFDGQALLHKFDFKEGHVTYYRRFIRTDAYVRAMTEKRIVITEFGTCAFPDPCKNIFSRFFSYFRGVEITDNALVNIYPVGEDYYACTETNFITKINPETLETIKQVDLCNYVSVNGATAHPHIESDGTVYNIGNCFGKNFTVAYNIIKIPPLKADKEDPINKSEVVVQFPCSDRFKPSYVHSFGLTPNYIVFVETPVKINLFKFLSSWSLWGANYMDCFESNESMGVWLHVADKKRRKYFNNKYRTSPFNLFHHINTYEDNGFLIVDLCCWKGFEFVYNYLYLANLRENWEEVKRNAMKAPQPEVRRYVLPLTIDKADTGRNLVTLPHTTATAILCSDETIWLEPEVLFSGPRQAFEFPQINYQKCGGKPYTYAYGLGLNHFVPDKLCKLNVKTKEIWMWQEPDSYPSEPIFVSQPDALEEDDGVVLSVVVSPGAGQKPAYLLVLNAKDLSEIARAEVETNIPVTFHGLFKKP | camera-type eye development circadian rhythm detection of light stimulus involved in visual perception neural retina development response to light stimulus retina homeostasis retinal metabolic process retinoid metabolic process retinol metabolic process zeaxanthin biosynthetic process cell body; cytoplasm; endoplasmic reticulum membrane; membrane; nucleus; plasma membrane all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity beta-carotene 15,15'-dioxygenase activity cardiolipin binding isomerase activity metal ion binding phosphatidylcholine binding phosphatidylserine binding retinol isomerase activity Rattus norvegicus Acetylation Cell membrane Cytoplasm Endoplasmic reticulum Hydrolase Iron Isomerase Lipid metabolism Lipoprotein Membrane Metal-binding Microsome Palmitate Phosphoprotein Reference proteome Sensory transduction Vision MSIQIEHPAG MSIQIEHPAGGYKKLFETVEELSTPLTAHVTGRIPLWLTGSLLRCGPGLFEVGSEPFYHLFDGQALLHKFDFKEGHVTYYRRFIRTDAYVRAMTEKRIVITEFGTCAFPDPCKNIFSRFFSYFRGVEITDNALVNIYPVGEDYYACTETNFITKINPETLETIKQVDLCNYVSVNGATAHPHIESDGTVYNIGNCFGKNFTVAYNIIKIPPLKADKEDPINKSEVVVQFPCSDRFKPSYVHSFGLTPNYIVFVETPVKINLFKFLSSWSLWGANYMDCFESNESMGVWLHVADKKRRKYFNNKYRTSPFNLFHHINTYEDNGFLIVDLCCWKGFEFVYNYLYLANLRENWEEVKRNAMKAPQPEVRRYVLPLTIDKADTGRNLVTLPHTTATAILCSDETIWLEPEVLFSGPRQAFEFPQINYQKCGGKPYTYAYGLGLNHFVPDKLCKLNVKTKEIWMWQEPDSYPSEPIFVSQPDALEEDDGVVLSVVVSPGAGQKPAYLLVLNAKDLSEIARAEVETNIPVTFHGLFKKP |
negative regulation of translation positive regulation of toll-like receptor 3 signaling pathway proteasome-mediated ubiquitin-dependent protein catabolic process protein K63-linked ubiquitination protein polyubiquitination protein transport protein ubiquitination regulation protein catabolic process at postsynapse | cytoplasm; dendrite; early endosome; glutamatergic synapse; Golgi apparatus; postsynapse | identical protein binding translation repressor activity ubiquitin protein ligase activity ubiquitin-protein transferase activity zinc ion binding | Rattus norvegicus | Acetylation Cell projection Coiled coil Cytoplasm Endosome Golgi apparatus Metal-binding Phosphoprotein Protein transport Reference proteome Repeat Transferase Transport Zinc Zinc-finger | MAKREDSPGP | MAKREDSPGPEVQPMDKQFLVCSICLDRYRCPKVLPCLHTFCERCLQNYIPPQSLTLSCPVCRQTSILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSAVAGRPLSCPNHEGKTMEFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVGGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLESICGAKQKVLQTQLDTLRQGQEHIGSSCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELVLEVDGLRRSVLNLGALLTTSAAAHETVATGEGLRQALVGQPASLTVTTKDKDGRLVRTGSAELCAEITGPDGMRLAVPVVDHKNGTYELVYTARTEGDLLLSVLLYGQPVRGSPFRVRALRPGDLPPSPDDVKRRVKSPGGPGSHVRQKAVRRPSSMYSTGGKRKDNPIVDELVFRVGSRGREKGEFTNLHPLSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGPKGVAVDRNGHIIVVDNKSCCVFTFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNHSVKVYSADGEFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTSAEPLYGPQGLALTSDGHVVVADAGNHCFKAYRYLQ | negative regulation of translation positive regulation of toll-like receptor 3 signaling pathway proteasome-mediated ubiquitin-dependent protein catabolic process protein K63-linked ubiquitination protein polyubiquitination protein transport protein ubiquitination regulation protein catabolic process at postsynapse cytoplasm; dendrite; early endosome; glutamatergic synapse; Golgi apparatus; postsynapse identical protein binding translation repressor activity ubiquitin protein ligase activity ubiquitin-protein transferase activity zinc ion binding Rattus norvegicus Acetylation Cell projection Coiled coil Cytoplasm Endosome Golgi apparatus Metal-binding Phosphoprotein Protein transport Reference proteome Repeat Transferase Transport Zinc Zinc-finger MAKREDSPGP MAKREDSPGPEVQPMDKQFLVCSICLDRYRCPKVLPCLHTFCERCLQNYIPPQSLTLSCPVCRQTSILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSAVAGRPLSCPNHEGKTMEFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVGGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLESICGAKQKVLQTQLDTLRQGQEHIGSSCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELVLEVDGLRRSVLNLGALLTTSAAAHETVATGEGLRQALVGQPASLTVTTKDKDGRLVRTGSAELCAEITGPDGMRLAVPVVDHKNGTYELVYTARTEGDLLLSVLLYGQPVRGSPFRVRALRPGDLPPSPDDVKRRVKSPGGPGSHVRQKAVRRPSSMYSTGGKRKDNPIVDELVFRVGSRGREKGEFTNLHPLSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGPKGVAVDRNGHIIVVDNKSCCVFTFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNHSVKVYSADGEFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTSAEPLYGPQGLALTSDGHVVVADAGNHCFKAYRYLQ |
peptidyl-tyrosine sulfation | Golgi apparatus; Golgi membrane | protein homodimerization activity protein-tyrosine sulfotransferase activity | Mus musculus | Disulfide bond Glycoprotein Golgi apparatus Membrane Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix | MVGKLKQNLL | MVGKLKQNLLLACLVISSVTVFYLGQHAMECHHRIEERSQPARLENPKATVRAGLDIKANKTFTYHKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWSRSSKEKIRLDEAGVTDEVLDSAMQAFLLEVIVKHGEPAPYLCNKDPFALKSLTYLARLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLHIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKPDPKILENTRRVYKGEFQLPDFLKEKPQTEQVE | peptidyl-tyrosine sulfation Golgi apparatus; Golgi membrane protein homodimerization activity protein-tyrosine sulfotransferase activity Mus musculus Disulfide bond Glycoprotein Golgi apparatus Membrane Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix MVGKLKQNLL MVGKLKQNLLLACLVISSVTVFYLGQHAMECHHRIEERSQPARLENPKATVRAGLDIKANKTFTYHKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWSRSSKEKIRLDEAGVTDEVLDSAMQAFLLEVIVKHGEPAPYLCNKDPFALKSLTYLARLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLHIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKPDPKILENTRRVYKGEFQLPDFLKEKPQTEQVE |
animal organ morphogenesis canonical Wnt signaling pathway cell fate commitment cell-cell signaling cellular response to starvation chondrocyte differentiation forebrain regionalization hematopoietic stem cell proliferation lung induction male gonad development mesenchymal-epithelial cell signaling neuron differentiation positive regulation of branching involved in ureteric bud morphogenesis signal transduction | extracellular space; intracellular membrane-bounded organelle | cytokine activity frizzled binding signaling receptor binding | Mus musculus | Developmental protein Disulfide bond Extracellular matrix Glycoprotein Lipoprotein Reference proteome Secreted Signal Wnt signaling pathway | MLKLQGEDEA | MLKLQGEDEAAQLAPRRARVPVPRPTAPDVSPSSARLGLACLLLLLLLTLPARVDTSWWYIGALGARVICDNIPGLVSRQRQLCQRYPDIMRSVGEGAREWIRECQHQFRHHRWNCTTLDRDHTVFGRAMLRSSREAAFVYAISSAGVVHAITRACSQGELSVCSCDPYTRGRHHDQRGDFDWGGCSDNIHYGVRFAKAFVDAKEKRLKDARALMNLHNNRCGRTAVRRFLKLECKCHGVSGSCTLRTCWRALSDFRRTGDYLRRRYDGAVQVTATQDGANFTAARQGYRHATRTDLVYFDNSPDYCVLDKAAGSLGTAGRVCSKTSKGTDGCEIMCCGRGYDTTRVTRVTQCECKFHWCCAVRCKECRNTVDVHTCKAPKKAEWLDQT | animal organ morphogenesis canonical Wnt signaling pathway cell fate commitment cell-cell signaling cellular response to starvation chondrocyte differentiation forebrain regionalization hematopoietic stem cell proliferation lung induction male gonad development mesenchymal-epithelial cell signaling neuron differentiation positive regulation of branching involved in ureteric bud morphogenesis signal transduction extracellular space; intracellular membrane-bounded organelle cytokine activity frizzled binding signaling receptor binding Mus musculus Developmental protein Disulfide bond Extracellular matrix Glycoprotein Lipoprotein Reference proteome Secreted Signal Wnt signaling pathway MLKLQGEDEA MLKLQGEDEAAQLAPRRARVPVPRPTAPDVSPSSARLGLACLLLLLLLTLPARVDTSWWYIGALGARVICDNIPGLVSRQRQLCQRYPDIMRSVGEGAREWIRECQHQFRHHRWNCTTLDRDHTVFGRAMLRSSREAAFVYAISSAGVVHAITRACSQGELSVCSCDPYTRGRHHDQRGDFDWGGCSDNIHYGVRFAKAFVDAKEKRLKDARALMNLHNNRCGRTAVRRFLKLECKCHGVSGSCTLRTCWRALSDFRRTGDYLRRRYDGAVQVTATQDGANFTAARQGYRHATRTDLVYFDNSPDYCVLDKAAGSLGTAGRVCSKTSKGTDGCEIMCCGRGYDTTRVTRVTQCECKFHWCCAVRCKECRNTVDVHTCKAPKKAEWLDQT |
desensitization of G protein-coupled receptor signaling pathway G protein-coupled receptor internalization phosphorylation receptor internalization regulation of signal transduction signal transduction | cell cortex; cytoplasm; cytosol; dendrite; neuronal cell body; plasma membrane | ATP binding protein kinase activity rhodopsin kinase activity | Mus musculus | Acetylation ATP-binding Cytoplasm Kinase Lipoprotein Nucleotide-binding Palmitate Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MELENFVANN | MELENFVANNLLLKARLGFNKQTGRSKKWRELLKFPPVSMCTELRWSIEKDFSSLCDKQPIGRLLFRQFCDTKPDLKRCIEFLDAVAEYEVTIEEEQREFGLAIFSRFFKEKSEVPLPEIPPDIVKECKWNLKQNSPSQNVFEECAGIVCKYLSETPFEEYQESTYFNRFLQWKWLERRPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKRILEKLHSRFVVSLAYTYETKDALCLVLTIMNGGDLKYHIYNLGDPGFEEPRAVFYAAELCCGLEDLQRKRIVYRDLKPENILLDDHGHIRISDLGLAMEVPEGEMVRGRVGTVGYMAPEIINHEKYTFSPDWWGLGCLIYEMIAGHSPFRKYKEKVNREELERRVKNETEEYSERFSEDAKSICSMLLIKDPSKRLGCQRDGVSAVKQHPIFKDINFSRLEANMLDPPFIPDPQAIYCRNILDIGQFSVVKGVNLDTNDEIFYAEFATGSVTIPWQNEMIESGCFKDLNENEDDLSSLEKYKMCSSILRPKRNFFRRLFRRTGCLNIALSEEREPTEH | desensitization of G protein-coupled receptor signaling pathway G protein-coupled receptor internalization phosphorylation receptor internalization regulation of signal transduction signal transduction cell cortex; cytoplasm; cytosol; dendrite; neuronal cell body; plasma membrane ATP binding protein kinase activity rhodopsin kinase activity Mus musculus Acetylation ATP-binding Cytoplasm Kinase Lipoprotein Nucleotide-binding Palmitate Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase MELENFVANN MELENFVANNLLLKARLGFNKQTGRSKKWRELLKFPPVSMCTELRWSIEKDFSSLCDKQPIGRLLFRQFCDTKPDLKRCIEFLDAVAEYEVTIEEEQREFGLAIFSRFFKEKSEVPLPEIPPDIVKECKWNLKQNSPSQNVFEECAGIVCKYLSETPFEEYQESTYFNRFLQWKWLERRPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKRILEKLHSRFVVSLAYTYETKDALCLVLTIMNGGDLKYHIYNLGDPGFEEPRAVFYAAELCCGLEDLQRKRIVYRDLKPENILLDDHGHIRISDLGLAMEVPEGEMVRGRVGTVGYMAPEIINHEKYTFSPDWWGLGCLIYEMIAGHSPFRKYKEKVNREELERRVKNETEEYSERFSEDAKSICSMLLIKDPSKRLGCQRDGVSAVKQHPIFKDINFSRLEANMLDPPFIPDPQAIYCRNILDIGQFSVVKGVNLDTNDEIFYAEFATGSVTIPWQNEMIESGCFKDLNENEDDLSSLEKYKMCSSILRPKRNFFRRLFRRTGCLNIALSEEREPTEH |
desensitization of G protein-coupled receptor signaling pathway phosphorylation regulation of signal transduction Wnt signaling pathway | cytoplasm; membrane | ATP binding beta-adrenergic receptor kinase activity G protein-coupled receptor kinase activity | Mus musculus | Alternative splicing ATP-binding Kinase Lipoprotein Membrane Nucleotide-binding Palmitate Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase Wnt signaling pathway | MELENIVANT | MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQPIGRLLFREFCATRPELTRCTAFLDGVSEYEVTPDEKRKACGRRLMQNFLSHTGPDLIPEVPRQLVSNCAQRLEQGPCKDLFQELTRLTHEYLSTAPFADYLDSIYFNRFLQWKWLERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVRNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVAEEYTDRFSSQARSLCSQLLSKDPAERLGCRGGGAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDIEQFSTVKGVDLEPTDQDFYQKFATGSVSIPWQNEMVETECFQELNVFGLDGSVPPDLDWKGQPTAPPKKGLLQRLFSRQDCCGNCSDSEEELPTRL | desensitization of G protein-coupled receptor signaling pathway phosphorylation regulation of signal transduction Wnt signaling pathway cytoplasm; membrane ATP binding beta-adrenergic receptor kinase activity G protein-coupled receptor kinase activity Mus musculus Alternative splicing ATP-binding Kinase Lipoprotein Membrane Nucleotide-binding Palmitate Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase Wnt signaling pathway MELENIVANT MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQPIGRLLFREFCATRPELTRCTAFLDGVSEYEVTPDEKRKACGRRLMQNFLSHTGPDLIPEVPRQLVSNCAQRLEQGPCKDLFQELTRLTHEYLSTAPFADYLDSIYFNRFLQWKWLERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVRNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVAEEYTDRFSSQARSLCSQLLSKDPAERLGCRGGGAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDIEQFSTVKGVDLEPTDQDFYQKFATGSVSIPWQNEMVETECFQELNVFGLDGSVPPDLDWKGQPTAPPKKGLLQRLFSRQDCCGNCSDSEEELPTRL |
camera-type eye development cell population proliferation eye development positive regulation of cell population proliferation | nucleus | metal ion binding nucleotide binding nucleotidyltransferase activity | Mus musculus | Developmental protein Magnesium Metal-binding Nucleotide-binding Nucleotidyltransferase Nucleus Reference proteome Transferase | MIAAQAKLVY | MIAAQAKLVYHLNKYYNEKCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLNEMDNRYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMVADTSEVKLRIRDRYVVQITPAFKCTGIWPRSAAHWPLPHIPWPGPNRVAEVKAEGFNLLSKECHSLAGKQSSAESDAWVLQFAEAENRLQMGGCRKKCLSILKTLRDRHLELPGQPLNNYHMKTLVSYECEKHPRESDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALENAAKQTWRLAREILTNPKSLEKL | camera-type eye development cell population proliferation eye development positive regulation of cell population proliferation nucleus metal ion binding nucleotide binding nucleotidyltransferase activity Mus musculus Developmental protein Magnesium Metal-binding Nucleotide-binding Nucleotidyltransferase Nucleus Reference proteome Transferase MIAAQAKLVY MIAAQAKLVYHLNKYYNEKCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLNEMDNRYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMVADTSEVKLRIRDRYVVQITPAFKCTGIWPRSAAHWPLPHIPWPGPNRVAEVKAEGFNLLSKECHSLAGKQSSAESDAWVLQFAEAENRLQMGGCRKKCLSILKTLRDRHLELPGQPLNNYHMKTLVSYECEKHPRESDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALENAAKQTWRLAREILTNPKSLEKL |
apoptotic process cellular response to cold lipid droplet fusion lipid metabolic process lipid storage negative regulation of cold-induced thermogenesis negative regulation of cytokine production negative regulation of execution phase of apoptosis negative regulation of lipid catabolic process negative regulation of transforming growth factor beta receptor signaling pathway negative regulation of tumor necrosis factor production positive regulation of sequestering of triglyceride regulation of apoptotic DNA fragmentation regulation of apoptotic process response to stilbenoid temperature homeostasis | cytoplasm; lipid droplet; mitochondrial envelope; mitochondrion; nucleus | lipid transfer activity phosphatidic acid binding protein homodimerization activity | Mus musculus | Activator Apoptosis Lipid droplet Nucleus Reference proteome Transcription Transcription regulation | METARDYAGA | METARDYAGALIRPLTFMGLQTKKVLLTPLIHPARPFRVSNHDRSSRRGVMASSLQELISKTLDVLVITTGLVTLVLEEDGTVVDTEEFFQTLRDNTHFMILEKGQKWTPGSKYVPVCKQPKKSGIARVTFDLYRLNPKDFLGCLNVKATMYEMYSVSYDIRCTSFKAVLRNLLRFMSYAAQMTGQFLVYAGTYMLRVLGDTEEQPSPKPSTKGWFM | apoptotic process cellular response to cold lipid droplet fusion lipid metabolic process lipid storage negative regulation of cold-induced thermogenesis negative regulation of cytokine production negative regulation of execution phase of apoptosis negative regulation of lipid catabolic process negative regulation of transforming growth factor beta receptor signaling pathway negative regulation of tumor necrosis factor production positive regulation of sequestering of triglyceride regulation of apoptotic DNA fragmentation regulation of apoptotic process response to stilbenoid temperature homeostasis cytoplasm; lipid droplet; mitochondrial envelope; mitochondrion; nucleus lipid transfer activity phosphatidic acid binding protein homodimerization activity Mus musculus Activator Apoptosis Lipid droplet Nucleus Reference proteome Transcription Transcription regulation METARDYAGA METARDYAGALIRPLTFMGLQTKKVLLTPLIHPARPFRVSNHDRSSRRGVMASSLQELISKTLDVLVITTGLVTLVLEEDGTVVDTEEFFQTLRDNTHFMILEKGQKWTPGSKYVPVCKQPKKSGIARVTFDLYRLNPKDFLGCLNVKATMYEMYSVSYDIRCTSFKAVLRNLLRFMSYAAQMTGQFLVYAGTYMLRVLGDTEEQPSPKPSTKGWFM |
apoptotic process COPII-coated vesicle cargo loading execution phase of apoptosis lipid droplet fusion lipid storage positive regulation of apoptotic process regulation of apoptotic process regulation of triglyceride metabolic process very-low-density lipoprotein particle assembly | COPI-coated vesicle; COPII vesicle coat; cytosol; endoplasmic reticulum; endoplasmic reticulum membrane; Golgi apparatus; lipid droplet; perinuclear region of cytoplasm | identical protein binding lipid transfer activity molecular adaptor activity phosphatidic acid binding | Mus musculus | Apoptosis Cytoplasmic vesicle Endoplasmic reticulum Golgi apparatus Lipid droplet Membrane Phosphoprotein Reference proteome | MEYLSAFNPN | MEYLSAFNPNGLLRSVSTVSSELSRRVWNSAPPPQRPFRVCDHKRTVRKGLTAASLQELLDKVLETLLLRGVLTLVLEEDGTAVDSEDFFQLLEDDTCLMVLEQGQSWSPKSGMLSYGLGREKPKHSKDIARITFDVYKQNPRDLFGSLNVKATFYGLYSMSCDFQGVGPKRVLRELLRWTSSLLQGLGHMLLGISSTLRHVVEGADRWQWHGQRHLHS | apoptotic process COPII-coated vesicle cargo loading execution phase of apoptosis lipid droplet fusion lipid storage positive regulation of apoptotic process regulation of apoptotic process regulation of triglyceride metabolic process very-low-density lipoprotein particle assembly COPI-coated vesicle; COPII vesicle coat; cytosol; endoplasmic reticulum; endoplasmic reticulum membrane; Golgi apparatus; lipid droplet; perinuclear region of cytoplasm identical protein binding lipid transfer activity molecular adaptor activity phosphatidic acid binding Mus musculus Apoptosis Cytoplasmic vesicle Endoplasmic reticulum Golgi apparatus Lipid droplet Membrane Phosphoprotein Reference proteome MEYLSAFNPN MEYLSAFNPNGLLRSVSTVSSELSRRVWNSAPPPQRPFRVCDHKRTVRKGLTAASLQELLDKVLETLLLRGVLTLVLEEDGTAVDSEDFFQLLEDDTCLMVLEQGQSWSPKSGMLSYGLGREKPKHSKDIARITFDVYKQNPRDLFGSLNVKATFYGLYSMSCDFQGVGPKRVLRELLRWTSSLLQGLGHMLLGISSTLRHVVEGADRWQWHGQRHLHS |
cell fate specification embryonic cranial skeleton morphogenesis embryonic skeletal system morphogenesis negative regulation of transcription by RNA polymerase II positive regulation of DNA-templated transcription regulation of transcription by RNA polymerase II | nucleus; RNA polymerase II transcription repressor complex | DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific protein homodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Mus musculus | DNA-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MSERRRSAVA | MSERRRSAVALSSRAHAFSVEALIGSNKKRKLRDWEEKGLDLSMEALSPAGPLGDTDDPATHGLEPHPDSEQSTGSDSEVLTERTSCSFSTHTDLASGAAGPVPAAMSSMEEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRTGLEAIMETYAFWRPPVRTLTFEDFTTMQKQQGGSTGTSPTTSSTGTPSPSASSHLLSPSCSPPTFHLAPNTFNVGCRESQLCNLNLSDYPPCARSNMAALQSYPGLSDSGYNRLQSGTASATQPSETFMPQRTPSLISGIPTPPSLPSNSKMEAYGGQLGSFPTSQFQYVMQAGNAASSSSSPHMFGGSHMQQSSYNAFSLHNPYNLYGYNFPTSPRLAASPEKLSASQSTLLCSSPSNGAFGERQYLPTGMEHSMHMISPSTNNQQATNTCDGRQYGAVPGSASQMSVHMV | cell fate specification embryonic cranial skeleton morphogenesis embryonic skeletal system morphogenesis negative regulation of transcription by RNA polymerase II positive regulation of DNA-templated transcription regulation of transcription by RNA polymerase II nucleus; RNA polymerase II transcription repressor complex DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific protein homodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding Mus musculus DNA-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation MSERRRSAVA MSERRRSAVALSSRAHAFSVEALIGSNKKRKLRDWEEKGLDLSMEALSPAGPLGDTDDPATHGLEPHPDSEQSTGSDSEVLTERTSCSFSTHTDLASGAAGPVPAAMSSMEEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRTGLEAIMETYAFWRPPVRTLTFEDFTTMQKQQGGSTGTSPTTSSTGTPSPSASSHLLSPSCSPPTFHLAPNTFNVGCRESQLCNLNLSDYPPCARSNMAALQSYPGLSDSGYNRLQSGTASATQPSETFMPQRTPSLISGIPTPPSLPSNSKMEAYGGQLGSFPTSQFQYVMQAGNAASSSSSPHMFGGSHMQQSSYNAFSLHNPYNLYGYNFPTSPRLAASPEKLSASQSTLLCSSPSNGAFGERQYLPTGMEHSMHMISPSTNNQQATNTCDGRQYGAVPGSASQMSVHMV |
cell migration cell-matrix adhesion epithelial cell-cell adhesion integrin-mediated signaling pathway stress fiber assembly transforming growth factor beta receptor signaling pathway | cell leading edge; cell surface; focal adhesion; glutamatergic synapse; integrin alphav-beta5 complex; integrin complex; plasma membrane; receptor complex; synaptic membrane | integrin binding metal ion binding | Mus musculus | Alternative splicing Calcium Cell adhesion Cell membrane Disulfide bond EGF-like domain Glycoprotein Integrin Magnesium Membrane Metal-binding Phosphoprotein Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix | MPRVPATLYA | MPRVPATLYACLLGLCALVPRLAGLNICTSGSATSCEECLLIHPKCAWCSKEYFGNPRSITSRCDLKANLIRNGCEGEIESPASSTHVLRNLPLSSKGSSATGSDVIQMTPQEIAVSLRPGEQTTFQLQVRQVEDYPVDLYYLMDLSLSMKDDLENIRSLGTKLAEEMRKLTSNFRLGFGSFVDKDISPFSYTAPRYQTNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVSRNRDAPEGGFDAVLQAAVCKEKIGWRKDALHLLVFTTDDVPHIALDGKLGGLVQPHDGQCHLNEANEYTASNQMDYPSLALLGEKLAENNINLIFAVTKNHYMLYKNFTALIPGTTVEILHGDSKNIIQLIINAYSSIRAKVELSVWDQPEDLNLFFTATCQDGISYPGQRKCEGLKIGDTASFEVSVEARSCPGRQAAQSFTLRPVGFRDSLQVEVAYNCTCGCSTGLEPNSARCSGNGTYTCGLCECDPGYLGTRCECQEGENQSGYQNLCREAEGKPLCSGRGECSCNQCSCFESEFGRIYGPFCECDSFSCARNKGVLCSGHGECHCGECKCHAGYIGDNCNCSTDVSTCKAKDGQICSDRGRCVCGQCQCTEPGAFGETCEKCPTCPDACSSKRDCVECLLLHQGKPDNQTCHHQCKDEVITWVDTIVKDDQEAVLCFYKTAKDCVMMFSYTELPNGRSNLTVLREPECGSAPNAMTILLAVVGSILLIGMALLAIWKLLVTIHDRREFAKFQSERSRARYEMASNPLYRKPISTHTVDFAFNKFNKSYNGSV | cell migration cell-matrix adhesion epithelial cell-cell adhesion integrin-mediated signaling pathway stress fiber assembly transforming growth factor beta receptor signaling pathway cell leading edge; cell surface; focal adhesion; glutamatergic synapse; integrin alphav-beta5 complex; integrin complex; plasma membrane; receptor complex; synaptic membrane integrin binding metal ion binding Mus musculus Alternative splicing Calcium Cell adhesion Cell membrane Disulfide bond EGF-like domain Glycoprotein Integrin Magnesium Membrane Metal-binding Phosphoprotein Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix MPRVPATLYA MPRVPATLYACLLGLCALVPRLAGLNICTSGSATSCEECLLIHPKCAWCSKEYFGNPRSITSRCDLKANLIRNGCEGEIESPASSTHVLRNLPLSSKGSSATGSDVIQMTPQEIAVSLRPGEQTTFQLQVRQVEDYPVDLYYLMDLSLSMKDDLENIRSLGTKLAEEMRKLTSNFRLGFGSFVDKDISPFSYTAPRYQTNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVSRNRDAPEGGFDAVLQAAVCKEKIGWRKDALHLLVFTTDDVPHIALDGKLGGLVQPHDGQCHLNEANEYTASNQMDYPSLALLGEKLAENNINLIFAVTKNHYMLYKNFTALIPGTTVEILHGDSKNIIQLIINAYSSIRAKVELSVWDQPEDLNLFFTATCQDGISYPGQRKCEGLKIGDTASFEVSVEARSCPGRQAAQSFTLRPVGFRDSLQVEVAYNCTCGCSTGLEPNSARCSGNGTYTCGLCECDPGYLGTRCECQEGENQSGYQNLCREAEGKPLCSGRGECSCNQCSCFESEFGRIYGPFCECDSFSCARNKGVLCSGHGECHCGECKCHAGYIGDNCNCSTDVSTCKAKDGQICSDRGRCVCGQCQCTEPGAFGETCEKCPTCPDACSSKRDCVECLLLHQGKPDNQTCHHQCKDEVITWVDTIVKDDQEAVLCFYKTAKDCVMMFSYTELPNGRSNLTVLREPECGSAPNAMTILLAVVGSILLIGMALLAIWKLLVTIHDRREFAKFQSERSRARYEMASNPLYRKPISTHTVDFAFNKFNKSYNGSV |
cellular ketone metabolic process in utero embryonic development N-terminal peptidyl-glycine N-myristoylation protein localization to membrane | cytoplasm; cytosol; plasma membrane | glycylpeptide N-tetradecanoyltransferase activity myristoyltransferase activity peptidyl-lysine N6-myristoyltransferase activity | Mus musculus | Acyltransferase Cytoplasm Membrane Phosphoprotein Reference proteome Transferase | MADESETAVK | MADESETAVKLPAPSLPLMMEGNGNGHEHCSDCENEEDNSHNRSGLSPANDTGAKKKKKKQKKKKEKGSDMESTQDQPVKMTSLPAERIQEIQKAIELFSVGQGPAKTMEEASKRSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMEKKDIPVVHQLLSRYLKQFHLTPVMNQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ | cellular ketone metabolic process in utero embryonic development N-terminal peptidyl-glycine N-myristoylation protein localization to membrane cytoplasm; cytosol; plasma membrane glycylpeptide N-tetradecanoyltransferase activity myristoyltransferase activity peptidyl-lysine N6-myristoyltransferase activity Mus musculus Acyltransferase Cytoplasm Membrane Phosphoprotein Reference proteome Transferase MADESETAVK MADESETAVKLPAPSLPLMMEGNGNGHEHCSDCENEEDNSHNRSGLSPANDTGAKKKKKKQKKKKEKGSDMESTQDQPVKMTSLPAERIQEIQKAIELFSVGQGPAKTMEEASKRSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMEKKDIPVVHQLLSRYLKQFHLTPVMNQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ |
actin cytoskeleton organization actomyosin structure organization cell cycle cell division cortical actin cytoskeleton organization positive regulation of protein localization to cell cortex regulation of cell shape | actin cytoskeleton; cell cortex; cell junction; COP9 signalosome; cytoskeleton; nucleoplasm; plasma membrane | actin binding PH domain binding spectrin binding structural molecule activity | Mus musculus | Acetylation Actin-binding Cell cycle Cell division Cell membrane Cytoplasm Cytoskeleton Membrane Mitosis Phosphoprotein Reference proteome Transport | MTTEVGSASE | MTTEVGSASEVKKGSDQAGADASKEKAKEVENEQTPVSEPEEEKGSQPGPPVERQSTPRLRKRGKDPSENRGISRFIPPWLKKQRSYNLVVAKDGGDKKEPTQADVEDQILGKEESLPEEESRAKGDAEEMAQRKHLEVQVEVREAKPALKSSVETQPAEEVRKDKEETIQDTQEEKLEGGAAKRETKEVQTSELKAEVASQKATKKTKTVLAKVTLLDGTEYSCDLEKRAKGQVLFDRVCEHLNLLEKDYFGLLFQDHPEQKNWLDPAKEIKRQLKNLPWLFTFNVKFYPPDPSQLTEDITRYFLCLQLRQDIASGRLPCSFVTHALLGSYTLQAEHGDYDPEEYDSIDLGDFQFAPAHTKELEEKVSELHKTHRGLSPAQADSQFLENAKRLSMYGVDLHHAKDSEGVDIKLGVCANGLLIYKDRLRINRFAWPKILKISYKRSNFYIKVRPAELEQFESTIGFKLPNHRAAKRLWKVCVEHHTFYRLVSPEQPPKTKFLTLGSKFRYSGRTQAQTREASTLIDRPAPQFERASSKRVSRSLDGAPIGVVDQSPPGEGSVPGPGVISYTTIQDGRRDSKSPTKATPLPAEGKKNTLRVDGDNIYVRHSNLMLEDLDKAQEAILKHQASISELKRNFMASTPEPRPSEWEKRRVTPLPFQPQASSHETLNVVEEKKRAEVGKDESVITEEMNGKEMSPGHGPGETRKVEPVAHKDSTSLSSESSSSSSESEEDVGEYQPHHRVTEGTIREEQEECDEELEEEPGQGAKVVEREAAVPDAVPDRQAGASVLPVETEAQEHVVAQKLPGEKGAHGGTAEQDPREEAEEDPHRVNGEVPHLDLDGLPEIICCSEPPVVKTEMVTISDASQRTEISTKEVPIVQTETKTITYESPQIDGGAGGDSGVLLTAQTITSESASTTTTTHITKTVKGGISETRIEKRIVITGDAALDHDQALAQAIREAREQHPDMSVTRVVVHKETELAEEGEE | actin cytoskeleton organization actomyosin structure organization cell cycle cell division cortical actin cytoskeleton organization positive regulation of protein localization to cell cortex regulation of cell shape actin cytoskeleton; cell cortex; cell junction; COP9 signalosome; cytoskeleton; nucleoplasm; plasma membrane actin binding PH domain binding spectrin binding structural molecule activity Mus musculus Acetylation Actin-binding Cell cycle Cell division Cell membrane Cytoplasm Cytoskeleton Membrane Mitosis Phosphoprotein Reference proteome Transport MTTEVGSASE MTTEVGSASEVKKGSDQAGADASKEKAKEVENEQTPVSEPEEEKGSQPGPPVERQSTPRLRKRGKDPSENRGISRFIPPWLKKQRSYNLVVAKDGGDKKEPTQADVEDQILGKEESLPEEESRAKGDAEEMAQRKHLEVQVEVREAKPALKSSVETQPAEEVRKDKEETIQDTQEEKLEGGAAKRETKEVQTSELKAEVASQKATKKTKTVLAKVTLLDGTEYSCDLEKRAKGQVLFDRVCEHLNLLEKDYFGLLFQDHPEQKNWLDPAKEIKRQLKNLPWLFTFNVKFYPPDPSQLTEDITRYFLCLQLRQDIASGRLPCSFVTHALLGSYTLQAEHGDYDPEEYDSIDLGDFQFAPAHTKELEEKVSELHKTHRGLSPAQADSQFLENAKRLSMYGVDLHHAKDSEGVDIKLGVCANGLLIYKDRLRINRFAWPKILKISYKRSNFYIKVRPAELEQFESTIGFKLPNHRAAKRLWKVCVEHHTFYRLVSPEQPPKTKFLTLGSKFRYSGRTQAQTREASTLIDRPAPQFERASSKRVSRSLDGAPIGVVDQSPPGEGSVPGPGVISYTTIQDGRRDSKSPTKATPLPAEGKKNTLRVDGDNIYVRHSNLMLEDLDKAQEAILKHQASISELKRNFMASTPEPRPSEWEKRRVTPLPFQPQASSHETLNVVEEKKRAEVGKDESVITEEMNGKEMSPGHGPGETRKVEPVAHKDSTSLSSESSSSSSESEEDVGEYQPHHRVTEGTIREEQEECDEELEEEPGQGAKVVEREAAVPDAVPDRQAGASVLPVETEAQEHVVAQKLPGEKGAHGGTAEQDPREEAEEDPHRVNGEVPHLDLDGLPEIICCSEPPVVKTEMVTISDASQRTEISTKEVPIVQTETKTITYESPQIDGGAGGDSGVLLTAQTITSESASTTTTTHITKTVKGGISETRIEKRIVITGDAALDHDQALAQAIREAREQHPDMSVTRVVVHKETELAEEGEE |
amino acid import across plasma membrane amino acid metabolic process hormone transport negative regulation of neural precursor cell proliferation thyroid hormone generation thyroid hormone metabolic process thyroid hormone transport thyroid-stimulating hormone secretion transport across blood-brain barrier | apical plasma membrane; plasma membrane | amino acid transmembrane transporter activity identical protein binding monocarboxylic acid transmembrane transporter activity thyroid hormone transmembrane transporter activity | Mus musculus | Acetylation Cell membrane Membrane Phosphoprotein Reference proteome Repeat Transmembrane Transmembrane helix Transport | MALPSPASEE | MALPSPASEEAEGPCQEANQEYQEPVCSPVPEPEPEPEPEPEPDPEPVPVPPPEPQPEPEPQPLPDPAPLPELGFEAEPVQEPEPTPTVETRGTARGFQPPEGGFGWIVVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNRQVEFQAAWVGALAMGMIFFCSPIVSIFTDRLGCRITATTGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFAFQPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIKMLGDKIKLAQTFQVLSTFMFVLTLLSLTYRPLLPSSQDTPSKRGAHTLRQRFLVQFRKYFNMRVFRQRTYRIWAFGIAAAALGYFVPYVHLMKYVEDKFKEIKETWVLLVCIGATSGLGRLVSGHISDSIPGLKKIYLQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFITIMAPIAFELVGPMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFGDYHVAFYFAGVPPIIGAVILFFVPLMHQRMFKKEQRDSSKDKMLSHDPDPNGELLPGSPTPEEPI | amino acid import across plasma membrane amino acid metabolic process hormone transport negative regulation of neural precursor cell proliferation thyroid hormone generation thyroid hormone metabolic process thyroid hormone transport thyroid-stimulating hormone secretion transport across blood-brain barrier apical plasma membrane; plasma membrane amino acid transmembrane transporter activity identical protein binding monocarboxylic acid transmembrane transporter activity thyroid hormone transmembrane transporter activity Mus musculus Acetylation Cell membrane Membrane Phosphoprotein Reference proteome Repeat Transmembrane Transmembrane helix Transport MALPSPASEE MALPSPASEEAEGPCQEANQEYQEPVCSPVPEPEPEPEPEPEPDPEPVPVPPPEPQPEPEPQPLPDPAPLPELGFEAEPVQEPEPTPTVETRGTARGFQPPEGGFGWIVVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNRQVEFQAAWVGALAMGMIFFCSPIVSIFTDRLGCRITATTGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFAFQPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIKMLGDKIKLAQTFQVLSTFMFVLTLLSLTYRPLLPSSQDTPSKRGAHTLRQRFLVQFRKYFNMRVFRQRTYRIWAFGIAAAALGYFVPYVHLMKYVEDKFKEIKETWVLLVCIGATSGLGRLVSGHISDSIPGLKKIYLQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFITIMAPIAFELVGPMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFGDYHVAFYFAGVPPIIGAVILFFVPLMHQRMFKKEQRDSSKDKMLSHDPDPNGELLPGSPTPEEPI |
arachidonic acid metabolic process chromatin organization lipoxygenase pathway negative regulation of ferroptosis protein polymerization response to estradiol response to oxidative stress spermatogenesis | cytosol; mitochondrial inner membrane; mitochondrion; nuclear envelope; nucleus; protein-containing complex | glutathione peroxidase activity identical protein binding phospholipid-hydroperoxide glutathione peroxidase activity selenium binding | Mus musculus | 3D-structure Alternative initiation Alternative splicing Cytoplasm Developmental protein Lipid metabolism Mitochondrion Nucleus Oxidoreductase Peroxidase Phosphoprotein Reference proteome Selenocysteine Transit peptide | MSWGRLSRLL | MSWGRLSRLLKPALLCGALAAPGLAGTMCASRDDWRCARSMHEFSAKDIDGHMVCLDKYRGFVCIVTNVASQUGKTDVNYTQLVDLHARYAECGLRILAFPCNQFGRQEPGSNQEIKEFAAGYNVKFDMYSKICVNGDDAHPLWKWMKVQPKGRGMLGNAIKWNFTKFLIDKNGCVVKRYGPMEEPQVIEKDLPCYL | arachidonic acid metabolic process chromatin organization lipoxygenase pathway negative regulation of ferroptosis protein polymerization response to estradiol response to oxidative stress spermatogenesis cytosol; mitochondrial inner membrane; mitochondrion; nuclear envelope; nucleus; protein-containing complex glutathione peroxidase activity identical protein binding phospholipid-hydroperoxide glutathione peroxidase activity selenium binding Mus musculus 3D-structure Alternative initiation Alternative splicing Cytoplasm Developmental protein Lipid metabolism Mitochondrion Nucleus Oxidoreductase Peroxidase Phosphoprotein Reference proteome Selenocysteine Transit peptide MSWGRLSRLL MSWGRLSRLLKPALLCGALAAPGLAGTMCASRDDWRCARSMHEFSAKDIDGHMVCLDKYRGFVCIVTNVASQUGKTDVNYTQLVDLHARYAECGLRILAFPCNQFGRQEPGSNQEIKEFAAGYNVKFDMYSKICVNGDDAHPLWKWMKVQPKGRGMLGNAIKWNFTKFLIDKNGCVVKRYGPMEEPQVIEKDLPCYL |
cytoplasmic microtubule organization establishment of protein localization mRNA processing protein localization to microtubule regulation of postsynaptic density assembly regulation of postsynaptic density protein 95 clustering RNA splicing | cytoplasm; dendrite; dendritic shaft; dendritic spine; glutamatergic synapse; neuronal cell body; postsynaptic density; postsynaptic density, intracellular component; spliceosomal complex | microtubule binding PDZ domain binding protein-containing complex binding scaffold protein binding | Mus musculus | Cell projection Cytoplasm mRNA processing mRNA splicing Reference proteome Spliceosome Synapse | MVCEKCEKKL | MVCEKCEKKLGRVITPDTWKDGARNTTESGGRKLNENKALTSKKARFDPYGKNKFSTCRICKSSVHQPGSHYCQGCAYKKGICAMCGKKVLDTKNYKQTSV | cytoplasmic microtubule organization establishment of protein localization mRNA processing protein localization to microtubule regulation of postsynaptic density assembly regulation of postsynaptic density protein 95 clustering RNA splicing cytoplasm; dendrite; dendritic shaft; dendritic spine; glutamatergic synapse; neuronal cell body; postsynaptic density; postsynaptic density, intracellular component; spliceosomal complex microtubule binding PDZ domain binding protein-containing complex binding scaffold protein binding Mus musculus Cell projection Cytoplasm mRNA processing mRNA splicing Reference proteome Spliceosome Synapse MVCEKCEKKL MVCEKCEKKLGRVITPDTWKDGARNTTESGGRKLNENKALTSKKARFDPYGKNKFSTCRICKSSVHQPGSHYCQGCAYKKGICAMCGKKVLDTKNYKQTSV |
apoptotic mitochondrial changes male gonad development positive regulation of protein-containing complex assembly positive regulation of release of cytochrome c from mitochondria regulation of apoptotic process spermatogenesis | Bcl-2 family protein complex; endomembrane system; mitochondrial envelope; mitochondrial membrane | BH domain binding protein-containing complex binding | Mus musculus | Apoptosis Membrane Mitochondrion Reference proteome Transmembrane Transmembrane helix | MSEARLMARD | MSEARLMARDVIKTVPHDQVPQPPVASETPSMKEPVRDVDLMECVEGRNQVALRLACIGDEMDLCLRSPRLVQLPGIAIHRLAVTYSRTGVRGIFRSLIRSLTNLRENIWSWRVLTPGAWVSPDQDPGQLFPMVLLVFLLLGGAWYLQLQ | apoptotic mitochondrial changes male gonad development positive regulation of protein-containing complex assembly positive regulation of release of cytochrome c from mitochondria regulation of apoptotic process spermatogenesis Bcl-2 family protein complex; endomembrane system; mitochondrial envelope; mitochondrial membrane BH domain binding protein-containing complex binding Mus musculus Apoptosis Membrane Mitochondrion Reference proteome Transmembrane Transmembrane helix MSEARLMARD MSEARLMARDVIKTVPHDQVPQPPVASETPSMKEPVRDVDLMECVEGRNQVALRLACIGDEMDLCLRSPRLVQLPGIAIHRLAVTYSRTGVRGIFRSLIRSLTNLRENIWSWRVLTPGAWVSPDQDPGQLFPMVLLVFLLLGGAWYLQLQ |
cardiac left ventricle morphogenesis chemical synaptic transmission eating behavior G protein-coupled receptor signaling pathway generation of ovulation cycle rhythm negative regulation of acute inflammatory response to antigenic stimulus negative regulation of apoptotic process negative regulation of glutamate secretion negative regulation of synaptic transmission, GABAergic outflow tract morphogenesis positive regulation of acute inflammatory response positive regulation of cell population proliferation positive regulation of ERK1 and ERK2 cascade positive regulation of smooth muscle cell proliferation synaptic signaling via neuropeptide | GABA-ergic synapse; membrane; neuron projection; plasma membrane; presynapse | neuropeptide binding neuropeptide Y receptor activity pancreatic polypeptide receptor activity peptide YY receptor activity | Mus musculus | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MEVKLEEHFN | MEVKLEEHFNKTFVTENNTAASQNTASPAWEDYRGTENNTSAARNTAFPVWEDYRGSVDDLQYFLIGLYTFVSLLGFMGNLLILMAVMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKAMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELKETFGSALLSSKYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSHKENRLEENEMINLTLHPSKKSRDQAKPPSTQKWSYSFIRKHRRRYSKKTACVLPAPAGPSQEKHLTVPENPGSVRSQLSPSSKVIPGVPICFEVKPEESSDAQEMRVKRSLTRIKKRSRSVFYRLTILILVFAVSWMPLHVFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLRALIHCLHMS | cardiac left ventricle morphogenesis chemical synaptic transmission eating behavior G protein-coupled receptor signaling pathway generation of ovulation cycle rhythm negative regulation of acute inflammatory response to antigenic stimulus negative regulation of apoptotic process negative regulation of glutamate secretion negative regulation of synaptic transmission, GABAergic outflow tract morphogenesis positive regulation of acute inflammatory response positive regulation of cell population proliferation positive regulation of ERK1 and ERK2 cascade positive regulation of smooth muscle cell proliferation synaptic signaling via neuropeptide GABA-ergic synapse; membrane; neuron projection; plasma membrane; presynapse neuropeptide binding neuropeptide Y receptor activity pancreatic polypeptide receptor activity peptide YY receptor activity Mus musculus Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix MEVKLEEHFN MEVKLEEHFNKTFVTENNTAASQNTASPAWEDYRGTENNTSAARNTAFPVWEDYRGSVDDLQYFLIGLYTFVSLLGFMGNLLILMAVMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKAMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELKETFGSALLSSKYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSHKENRLEENEMINLTLHPSKKSRDQAKPPSTQKWSYSFIRKHRRRYSKKTACVLPAPAGPSQEKHLTVPENPGSVRSQLSPSSKVIPGVPICFEVKPEESSDAQEMRVKRSLTRIKKRSRSVFYRLTILILVFAVSWMPLHVFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLRALIHCLHMS |
mRNA catabolic process NAD-cap decapping nuclear mRNA surveillance nuclear-transcribed mRNA catabolic process nucleic acid metabolic process RNA destabilization | cytosol; nucleoplasm; nucleus; plasma membrane | 5'-3' exonuclease activity magnesium ion binding mRNA 5'-diphosphatase activity mRNA binding nucleotide binding RNA NAD-cap (NAD-forming) hydrolase activity | Mus musculus | 3D-structure Exonuclease Hydrolase Magnesium Metal-binding Nuclease Nucleotide-binding Nucleus Phosphoprotein Reference proteome RNA-binding | MEPRGTKRKA | MEPRGTKRKAEKTEVEKPLNKLPRAVPSLRTQPSLYSGPFPFYRRPSELGCFSLDAQRQYHGDARALRYYSPPPINGPGPDFDLRDGYPDRYQPRDEEVQERLDHLLRWVLEHRNQLEGGPGWLAGATVTWRGHLTKLLTTPYERQEGWQLAASRFQGTLYLSEVETPAARAQRLARPPLLRELMYMGYKFEQYMCADKPGGSPDPSGEVNTNVAYCSVLRSRLGNHPLLFSGEVDCLNPQAPCTQPPSCYVELKTSKEMHSPGQWRSFYRHKLLKWWAQSFLPGVPHVVAGFRNPEGFVCSLKTFPTMEMFENVRNDREGWNPSVCMNFCAAFLSFAQSTVVQDDPRLVHLFSWEPGGPVTVSVHRDAPYAFLPSWYVETMTQDLPPLSKTPSPKD | mRNA catabolic process NAD-cap decapping nuclear mRNA surveillance nuclear-transcribed mRNA catabolic process nucleic acid metabolic process RNA destabilization cytosol; nucleoplasm; nucleus; plasma membrane 5'-3' exonuclease activity magnesium ion binding mRNA 5'-diphosphatase activity mRNA binding nucleotide binding RNA NAD-cap (NAD-forming) hydrolase activity Mus musculus 3D-structure Exonuclease Hydrolase Magnesium Metal-binding Nuclease Nucleotide-binding Nucleus Phosphoprotein Reference proteome RNA-binding MEPRGTKRKA MEPRGTKRKAEKTEVEKPLNKLPRAVPSLRTQPSLYSGPFPFYRRPSELGCFSLDAQRQYHGDARALRYYSPPPINGPGPDFDLRDGYPDRYQPRDEEVQERLDHLLRWVLEHRNQLEGGPGWLAGATVTWRGHLTKLLTTPYERQEGWQLAASRFQGTLYLSEVETPAARAQRLARPPLLRELMYMGYKFEQYMCADKPGGSPDPSGEVNTNVAYCSVLRSRLGNHPLLFSGEVDCLNPQAPCTQPPSCYVELKTSKEMHSPGQWRSFYRHKLLKWWAQSFLPGVPHVVAGFRNPEGFVCSLKTFPTMEMFENVRNDREGWNPSVCMNFCAAFLSFAQSTVVQDDPRLVHLFSWEPGGPVTVSVHRDAPYAFLPSWYVETMTQDLPPLSKTPSPKD |
androgen metabolic process bile acid biosynthetic process brexanolone metabolic process C21-steroid hormone metabolic process estrogen metabolic process fatty acid beta-oxidation fatty acid metabolic process isoleucine catabolic process Leydig cell differentiation male gonad development mitochondrial tRNA 3'-end processing mitochondrial tRNA 5'-end processing mitochondrial tRNA methylation mitochondrion organization protein homotetramerization | endoplasmic reticulum; mitochondrial nucleoid; mitochondrial ribonuclease P complex; mitochondrion; tRNA methyltransferase complex | 17-beta-hydroxysteroid dehydrogenase (NAD+) activity 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity 3-hydroxyacyl-CoA dehydrogenase activity acetoacetyl-CoA reductase activity amyloid-beta binding androstan-3-alpha,17-beta-diol dehydrogenase activity chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity cholate 7-alpha-dehydrogenase activity estradiol 17-beta-dehydrogenase activity identical protein binding isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity NAD binding nuclear estrogen receptor binding steroid binding testosterone dehydrogenase (NAD+) activity testosterone dehydrogenase activity tRNA binding ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity | Rattus norvegicus | 3D-structure Acetylation Direct protein sequencing Fatty acid metabolism Lipid metabolism Mitochondrion Mitochondrion nucleoid NAD Oxidoreductase Reference proteome Steroid metabolism tRNA processing | MAAAVRSVKG | MAAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIENPFLNGEVIRLDGAIRMQP | androgen metabolic process bile acid biosynthetic process brexanolone metabolic process C21-steroid hormone metabolic process estrogen metabolic process fatty acid beta-oxidation fatty acid metabolic process isoleucine catabolic process Leydig cell differentiation male gonad development mitochondrial tRNA 3'-end processing mitochondrial tRNA 5'-end processing mitochondrial tRNA methylation mitochondrion organization protein homotetramerization endoplasmic reticulum; mitochondrial nucleoid; mitochondrial ribonuclease P complex; mitochondrion; tRNA methyltransferase complex 17-beta-hydroxysteroid dehydrogenase (NAD+) activity 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity 3-hydroxyacyl-CoA dehydrogenase activity acetoacetyl-CoA reductase activity amyloid-beta binding androstan-3-alpha,17-beta-diol dehydrogenase activity chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity cholate 7-alpha-dehydrogenase activity estradiol 17-beta-dehydrogenase activity identical protein binding isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity NAD binding nuclear estrogen receptor binding steroid binding testosterone dehydrogenase (NAD+) activity testosterone dehydrogenase activity tRNA binding ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity Rattus norvegicus 3D-structure Acetylation Direct protein sequencing Fatty acid metabolism Lipid metabolism Mitochondrion Mitochondrion nucleoid NAD Oxidoreductase Reference proteome Steroid metabolism tRNA processing MAAAVRSVKG MAAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIENPFLNGEVIRLDGAIRMQP |
negative regulation of T cell receptor signaling pathway positive regulation of interleukin-2 production positive regulation of T cell proliferation regulation of cytokine production T cell receptor signaling pathway | external side of plasma membrane | signaling receptor binding | Mus musculus | 3D-structure Alternative splicing Disulfide bond Glycoprotein Immunoglobulin domain Membrane Reference proteome Repeat Signal-anchor Transmembrane Transmembrane helix | MVDCPRYSLS | MVDCPRYSLSGVAASFLFVLLTIKHPDDFRVVGPNLPILAKVGEDALLTCQLLPKRTTAHMEVRWYRSDPDMPVIMYRDGAEVTGLPMEGYGGRAEWMEDSTEEGSVALKIRQVQPSDDGQYWCRFQEGDYWRETSVLLQVAALGSSPNIHVEGLGEGEVQLVCTSRGWFPEPEVHWEGIWGEKLMSFSENHVPGEDGLFYVEDTLMVRNDSVETISCFIYSHGLRETQEATIALSERLQTELASVSVIGHSQPSPVQVGENIELTCHLSPQTDAQNLEVRWLRSRYYPAVHVYANGTHVAGEQMVEYKGRTSLVTDAIHEGKLTLQIHNARTSDEGQYRCLFGKDGVYQEARVDVQVMAVGSTPRITREVLKDGGMQLRCTSDGWFPRPHVQWRDRDGKTMPSFSEAFQQGSQELFQVETLLLVTNGSMVNVTCSISLPLGQEKTARFPLSGW | negative regulation of T cell receptor signaling pathway positive regulation of interleukin-2 production positive regulation of T cell proliferation regulation of cytokine production T cell receptor signaling pathway external side of plasma membrane signaling receptor binding Mus musculus 3D-structure Alternative splicing Disulfide bond Glycoprotein Immunoglobulin domain Membrane Reference proteome Repeat Signal-anchor Transmembrane Transmembrane helix MVDCPRYSLS MVDCPRYSLSGVAASFLFVLLTIKHPDDFRVVGPNLPILAKVGEDALLTCQLLPKRTTAHMEVRWYRSDPDMPVIMYRDGAEVTGLPMEGYGGRAEWMEDSTEEGSVALKIRQVQPSDDGQYWCRFQEGDYWRETSVLLQVAALGSSPNIHVEGLGEGEVQLVCTSRGWFPEPEVHWEGIWGEKLMSFSENHVPGEDGLFYVEDTLMVRNDSVETISCFIYSHGLRETQEATIALSERLQTELASVSVIGHSQPSPVQVGENIELTCHLSPQTDAQNLEVRWLRSRYYPAVHVYANGTHVAGEQMVEYKGRTSLVTDAIHEGKLTLQIHNARTSDEGQYRCLFGKDGVYQEARVDVQVMAVGSTPRITREVLKDGGMQLRCTSDGWFPRPHVQWRDRDGKTMPSFSEAFQQGSQELFQVETLLLVTNGSMVNVTCSISLPLGQEKTARFPLSGW |
antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of peptide antigen basement membrane disassembly bone resorption collagen catabolic process immune response positive regulation of apoptotic signaling pathway positive regulation of cation channel activity positive regulation of inflammatory response protein processing proteolysis proteolysis involved in protein catabolic process response to acidic pH | cell surface; early endosome lumen; extracellular space; intracellular membrane-bounded organelle; late endosome; lysosome; membrane; phagocytic vesicle | collagen binding cysteine-type endopeptidase activator activity involved in apoptotic process cysteine-type endopeptidase activity cysteine-type peptidase activity fibronectin binding laminin binding peptidase activity proteoglycan binding | Mus musculus | 3D-structure Cytoplasmic vesicle Disulfide bond Glycoprotein Hydrolase Lysosome Protease Reference proteome Secreted Signal Thiol protease Zymogen | MRAPGHAAIR | MRAPGHAAIRWLFWMPLVCSVAMEQLQRDPTLDYHWDLWKKTHEKEYKDKNEEEVRRLIWEKNLKFIMIHNLEYSMGMHTYQVGMNDMGDMTNEEILCRMGALRIPRQSPKTVTFRSYSNRTLPDTVDWREKGCVTEVKYQGSCGACWAFSAVGALEGQLKLKTGKLISLSAQNLVDCSNEEKYGNKGCGGGYMTEAFQYIIDNGGIEADASYPYKATDEKCHYNSKNRAATCSRYIQLPFGDEDALKEAVATKGPVSVGIDASHSSFFFYKSGVYDDPSCTGNVNHGVLVVGYGTLDGKDYWLVKNSWGLNFGDQGYIRMARNNKNHCGIASYCSYPEI | antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of peptide antigen basement membrane disassembly bone resorption collagen catabolic process immune response positive regulation of apoptotic signaling pathway positive regulation of cation channel activity positive regulation of inflammatory response protein processing proteolysis proteolysis involved in protein catabolic process response to acidic pH cell surface; early endosome lumen; extracellular space; intracellular membrane-bounded organelle; late endosome; lysosome; membrane; phagocytic vesicle collagen binding cysteine-type endopeptidase activator activity involved in apoptotic process cysteine-type endopeptidase activity cysteine-type peptidase activity fibronectin binding laminin binding peptidase activity proteoglycan binding Mus musculus 3D-structure Cytoplasmic vesicle Disulfide bond Glycoprotein Hydrolase Lysosome Protease Reference proteome Secreted Signal Thiol protease Zymogen MRAPGHAAIR MRAPGHAAIRWLFWMPLVCSVAMEQLQRDPTLDYHWDLWKKTHEKEYKDKNEEEVRRLIWEKNLKFIMIHNLEYSMGMHTYQVGMNDMGDMTNEEILCRMGALRIPRQSPKTVTFRSYSNRTLPDTVDWREKGCVTEVKYQGSCGACWAFSAVGALEGQLKLKTGKLISLSAQNLVDCSNEEKYGNKGCGGGYMTEAFQYIIDNGGIEADASYPYKATDEKCHYNSKNRAATCSRYIQLPFGDEDALKEAVATKGPVSVGIDASHSSFFFYKSGVYDDPSCTGNVNHGVLVVGYGTLDGKDYWLVKNSWGLNFGDQGYIRMARNNKNHCGIASYCSYPEI |
DNA-templated transcription epithelial cell differentiation intestinal epithelial cell differentiation negative regulation of DNA-templated transcription negative regulation of neuron projection development negative regulation of Notch signaling pathway negative regulation of transcription by RNA polymerase II positive regulation of neuron projection development | nucleus | metal ion binding transcription corepressor activity | Mus musculus | 3D-structure Alternative splicing Coiled coil Direct protein sequencing Isopeptide bond Metal-binding Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | MVGVPGAAAF | MVGVPGAAAFQLGCEKRVPAMPGSPVEVKIQSRSSPPIMPPLPPINPGGPRPVSFTPTALSNGINHSPPTLNGAPSPPQRFSNGPASSTSSALTNQQLPATCGARQLSKLKRFLTTLQQFGNDISPEIGEKVRTLVLALVNSTVTIEEFHCKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARAAKQTPSQYLAQHEHLLLNTSIASPADSSELLMEVHGNGKRPSPERRDENNFERDTVPPEPPAKRVCTISPAPRHSPALTVPLMNPGGQFHPTPPPLQHYTLEDIATSHLYREPNKMLEHREVRERHHNLSLNGGYQDELVDHRLTEREWADEWKHLDHALNCIMEMVEKTRRSMAVLRRCQESDREELNYWKRRFNENTELRKTGTELVSRQHSPGSTDSLSNDSQREFTSRPATGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTENCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQSLHGHSPHSQSRPLLPGGRGSARSADCSVPSPALDKTSATTSRSSTPASVTAIDANGL | DNA-templated transcription epithelial cell differentiation intestinal epithelial cell differentiation negative regulation of DNA-templated transcription negative regulation of neuron projection development negative regulation of Notch signaling pathway negative regulation of transcription by RNA polymerase II positive regulation of neuron projection development nucleus metal ion binding transcription corepressor activity Mus musculus 3D-structure Alternative splicing Coiled coil Direct protein sequencing Isopeptide bond Metal-binding Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger MVGVPGAAAF MVGVPGAAAFQLGCEKRVPAMPGSPVEVKIQSRSSPPIMPPLPPINPGGPRPVSFTPTALSNGINHSPPTLNGAPSPPQRFSNGPASSTSSALTNQQLPATCGARQLSKLKRFLTTLQQFGNDISPEIGEKVRTLVLALVNSTVTIEEFHCKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARAAKQTPSQYLAQHEHLLLNTSIASPADSSELLMEVHGNGKRPSPERRDENNFERDTVPPEPPAKRVCTISPAPRHSPALTVPLMNPGGQFHPTPPPLQHYTLEDIATSHLYREPNKMLEHREVRERHHNLSLNGGYQDELVDHRLTEREWADEWKHLDHALNCIMEMVEKTRRSMAVLRRCQESDREELNYWKRRFNENTELRKTGTELVSRQHSPGSTDSLSNDSQREFTSRPATGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTENCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQSLHGHSPHSQSRPLLPGGRGSARSADCSVPSPALDKTSATTSRSSTPASVTAIDANGL |
exocytic insertion of neurotransmitter receptor to postsynaptic membrane exocytosis histamine secretion by mast cell membrane fusion protein-containing complex assembly regulation of exocytosis synaptic vesicle fusion to presynaptic active zone membrane synaptic vesicle priming vesicle-mediated transport vesicle-mediated transport in synapse | adherens junction; azurophil granule; cytoplasm; cytoplasmic vesicle; cytoplasmic vesicle membrane; GABA-ergic synapse; glutamatergic synapse; mitochondrion; plasma membrane; postsynapse; SNARE complex; specific granule; synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex; terminal bouton | SNAP receptor activity syntaxin binding syntaxin-1 binding | Rattus norvegicus | Acetylation Cell membrane Coiled coil Cytoplasmic vesicle Direct protein sequencing Lipoprotein Membrane Palmitate Phosphoprotein Protein transport Reference proteome Repeat Synapse Synaptosome Transport | MDDLSPEEIQ | MDDLSPEEIQLRAHQVTDESLESTRRILGLAIESQDAGIKTITMLDEQGEQLNRIEEGMDQINKDMREAEKTLTELNKCCGLCVCPCNRTKNFESGKNYKATWGDGGDSSPSNVVSKQPSRITNGQPQQTTGAASGGYIKRITNDAREDEMEENLTQVGSILGNLKNMALDMGNEIDAQNQQIQKITEKADTNKNRIDIANTRAKKLIDS | exocytic insertion of neurotransmitter receptor to postsynaptic membrane exocytosis histamine secretion by mast cell membrane fusion protein-containing complex assembly regulation of exocytosis synaptic vesicle fusion to presynaptic active zone membrane synaptic vesicle priming vesicle-mediated transport vesicle-mediated transport in synapse adherens junction; azurophil granule; cytoplasm; cytoplasmic vesicle; cytoplasmic vesicle membrane; GABA-ergic synapse; glutamatergic synapse; mitochondrion; plasma membrane; postsynapse; SNARE complex; specific granule; synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex; terminal bouton SNAP receptor activity syntaxin binding syntaxin-1 binding Rattus norvegicus Acetylation Cell membrane Coiled coil Cytoplasmic vesicle Direct protein sequencing Lipoprotein Membrane Palmitate Phosphoprotein Protein transport Reference proteome Repeat Synapse Synaptosome Transport MDDLSPEEIQ MDDLSPEEIQLRAHQVTDESLESTRRILGLAIESQDAGIKTITMLDEQGEQLNRIEEGMDQINKDMREAEKTLTELNKCCGLCVCPCNRTKNFESGKNYKATWGDGGDSSPSNVVSKQPSRITNGQPQQTTGAASGGYIKRITNDAREDEMEENLTQVGSILGNLKNMALDMGNEIDAQNQQIQKITEKADTNKNRIDIANTRAKKLIDS |
cytokine-mediated signaling pathway defense response to Gram-positive bacterium negative regulation of cellular extravasation negative regulation of interleukin-17 production negative regulation of interleukin-6 production negative regulation of neuron apoptotic process negative regulation of T cell extravasation negative regulation of T-helper 17 type immune response negative regulation of tumor necrosis factor production negative regulation of type 2 immune response positive regulation of T-helper 1 type immune response positive regulation of type II interferon production regulation of isotype switching to IgG isotypes | cytoplasm; external side of plasma membrane; extracellular region; plasma membrane; receptor complex | cytokine binding interleukin-27 receptor activity | Mus musculus | 3D-structure Glycoprotein Membrane Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix | MNRLRVARLT | MNRLRVARLTPLELLLSLMSLLLGTRPHGSPGPLQCYSVGPLGILNCSWEPLGDLETPPVLYHQSQKYHPNRVWEVKVPSKQSWVTIPREQFTMADKLLIWGTQKGRPLWSSVSVNLETQMKPDTPQIFSQVDISEEATLEATVQWAPPVWPPQKVLICQFRYKECQAETWTRLEPQLKTDGLTPVEMQNLEPGTCYQVSGRCQVENGYPWGEWSSPLSFQTPFLDPEDVWVSGTVCETSGKRAALLVWKDPRPCVQVTYTVWFGAGDITTTQEEVPCCKSPVPAWMEWAVVSPGNSTSWVPPTNLSLVCLAPESAPCDVGVSSADGSPGIKVTWKQGTRKPLEYVVDWAQDGDSLDKLNWTRLPPGNLSTLLPGEFKGGVPYRITVTAVYSGGLAAAPSVWGFREELVPLAGPAVWRLPDDPPGTPVVAWGEVPRHQLRGQATHYTFCIQSRGLSTVCRNVSSQTQTATLPNLHLGSFKLWVTVSTVAGQGPPGPNLSLHLPDNRIRWKALPWFLSLWGLLLMGCGLSLASTRCLQARCLHWRHKLLPQWIWERVPDPANSNSGQPYIKEVSLPQPPKDGPILEVEEVELQPVVESPKASAPIYSGYEKHFLPTPEELGLLV | cytokine-mediated signaling pathway defense response to Gram-positive bacterium negative regulation of cellular extravasation negative regulation of interleukin-17 production negative regulation of interleukin-6 production negative regulation of neuron apoptotic process negative regulation of T cell extravasation negative regulation of T-helper 17 type immune response negative regulation of tumor necrosis factor production negative regulation of type 2 immune response positive regulation of T-helper 1 type immune response positive regulation of type II interferon production regulation of isotype switching to IgG isotypes cytoplasm; external side of plasma membrane; extracellular region; plasma membrane; receptor complex cytokine binding interleukin-27 receptor activity Mus musculus 3D-structure Glycoprotein Membrane Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix MNRLRVARLT MNRLRVARLTPLELLLSLMSLLLGTRPHGSPGPLQCYSVGPLGILNCSWEPLGDLETPPVLYHQSQKYHPNRVWEVKVPSKQSWVTIPREQFTMADKLLIWGTQKGRPLWSSVSVNLETQMKPDTPQIFSQVDISEEATLEATVQWAPPVWPPQKVLICQFRYKECQAETWTRLEPQLKTDGLTPVEMQNLEPGTCYQVSGRCQVENGYPWGEWSSPLSFQTPFLDPEDVWVSGTVCETSGKRAALLVWKDPRPCVQVTYTVWFGAGDITTTQEEVPCCKSPVPAWMEWAVVSPGNSTSWVPPTNLSLVCLAPESAPCDVGVSSADGSPGIKVTWKQGTRKPLEYVVDWAQDGDSLDKLNWTRLPPGNLSTLLPGEFKGGVPYRITVTAVYSGGLAAAPSVWGFREELVPLAGPAVWRLPDDPPGTPVVAWGEVPRHQLRGQATHYTFCIQSRGLSTVCRNVSSQTQTATLPNLHLGSFKLWVTVSTVAGQGPPGPNLSLHLPDNRIRWKALPWFLSLWGLLLMGCGLSLASTRCLQARCLHWRHKLLPQWIWERVPDPANSNSGQPYIKEVSLPQPPKDGPILEVEEVELQPVVESPKASAPIYSGYEKHFLPTPEELGLLV |
actin cytoskeleton organization establishment or maintenance of actin cytoskeleton polarity fibroblast migration heart development maintenance of cell polarity muscle structure development regulation of transcription by RNA polymerase II response to hypoxia stress fiber assembly | actin cytoskeleton; adherens junction; cytoplasm; cytoskeleton; filamentous actin; stress fiber; transcription regulator complex; Z disc | actin binding metal ion binding muscle alpha-actinin binding transcription coactivator activity | Mus musculus | Acetylation Cytoplasm Cytoskeleton LIM domain Metal-binding Phosphoprotein Reference proteome Zinc | MTTQQIVLQG | MTTQQIVLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAAIANLCIGDLITAIDGEDTSSMTHLEAQNKIKGCADNMTLTVSRSEQKIWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAHNRSAMPFTASPAPSTRVITNQYNSPTGLYSSENISNFNNAVESKTSASGEEANSRPVVQPHPSGSLIIDKDSEVYKMLQEKQELNEPPKQSTSFLVLQEILESDGKGDPNKPSGFRSVKAPVTKVAASVGNAQKLPICDKCGTGIVGVFVKLRDHHRHPECYVCTDCGINLKQKGHFFVEDQIYCEKHARERVTPPEGYDVVTVFRE | actin cytoskeleton organization establishment or maintenance of actin cytoskeleton polarity fibroblast migration heart development maintenance of cell polarity muscle structure development regulation of transcription by RNA polymerase II response to hypoxia stress fiber assembly actin cytoskeleton; adherens junction; cytoplasm; cytoskeleton; filamentous actin; stress fiber; transcription regulator complex; Z disc actin binding metal ion binding muscle alpha-actinin binding transcription coactivator activity Mus musculus Acetylation Cytoplasm Cytoskeleton LIM domain Metal-binding Phosphoprotein Reference proteome Zinc MTTQQIVLQG MTTQQIVLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAAIANLCIGDLITAIDGEDTSSMTHLEAQNKIKGCADNMTLTVSRSEQKIWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAHNRSAMPFTASPAPSTRVITNQYNSPTGLYSSENISNFNNAVESKTSASGEEANSRPVVQPHPSGSLIIDKDSEVYKMLQEKQELNEPPKQSTSFLVLQEILESDGKGDPNKPSGFRSVKAPVTKVAASVGNAQKLPICDKCGTGIVGVFVKLRDHHRHPECYVCTDCGINLKQKGHFFVEDQIYCEKHARERVTPPEGYDVVTVFRE |
autophagosome maturation autophagosome membrane docking cellular response to type II interferon defense response to virus establishment of localization in cell membrane fusion mucus secretion negative regulation of secretion by cell positive regulation of histamine secretion by mast cell positive regulation of pancreatic amylase secretion protein transport protein-containing complex assembly regulation of endocytosis regulation of protein localization to plasma membrane SNARE complex assembly vesicle fusion vesicle-mediated transport viral entry into host cell zymogen granule exocytosis | azurophil granule membrane; basal part of cell; basolateral part of cell; basolateral plasma membrane; cell surface; cytoplasm; cytosol; early endosome; early endosome membrane; late endosome membrane; lysosomal membrane; lysosome; membrane; midbody; mitochondrion; mucin granule; perinuclear region of cytoplasm; phagocytic vesicle; plasma membrane; recycling endosome; secretory granule; secretory granule membrane; SNARE complex; vesicle; zymogen granule; zymogen granule membrane | chloride channel inhibitor activity SNAP receptor activity syntaxin binding | Mus musculus | 3D-structure Acetylation Antiviral defense Autophagy Cell membrane Coiled coil Cytoplasmic vesicle Endosome Lysosome Membrane Phosphoprotein Protein transport Reference proteome Transmembrane Transmembrane helix Transport | MEEASGSAGN | MEEASGSAGNDRVRNLQSEVEGVKNIMTQNVERILSRGENLDHLRNKTEDLEATSEHFKTTSQKVARKFWWKNVKMIVIICVIVLIIVILIILFATGTIPT | autophagosome maturation autophagosome membrane docking cellular response to type II interferon defense response to virus establishment of localization in cell membrane fusion mucus secretion negative regulation of secretion by cell positive regulation of histamine secretion by mast cell positive regulation of pancreatic amylase secretion protein transport protein-containing complex assembly regulation of endocytosis regulation of protein localization to plasma membrane SNARE complex assembly vesicle fusion vesicle-mediated transport viral entry into host cell zymogen granule exocytosis azurophil granule membrane; basal part of cell; basolateral part of cell; basolateral plasma membrane; cell surface; cytoplasm; cytosol; early endosome; early endosome membrane; late endosome membrane; lysosomal membrane; lysosome; membrane; midbody; mitochondrion; mucin granule; perinuclear region of cytoplasm; phagocytic vesicle; plasma membrane; recycling endosome; secretory granule; secretory granule membrane; SNARE complex; vesicle; zymogen granule; zymogen granule membrane chloride channel inhibitor activity SNAP receptor activity syntaxin binding Mus musculus 3D-structure Acetylation Antiviral defense Autophagy Cell membrane Coiled coil Cytoplasmic vesicle Endosome Lysosome Membrane Phosphoprotein Protein transport Reference proteome Transmembrane Transmembrane helix Transport MEEASGSAGN MEEASGSAGNDRVRNLQSEVEGVKNIMTQNVERILSRGENLDHLRNKTEDLEATSEHFKTTSQKVARKFWWKNVKMIVIICVIVLIIVILIILFATGTIPT |
embryonic brain development endoplasmic reticulum organization G1 to G0 transition involved in cell differentiation neuron differentiation positive regulation of glial cell differentiation positive regulation of neuron differentiation protein autoubiquitination protein homooligomerization regulation of cell cycle response to hydroperoxide | cell body; cytoplasm; endosome; membrane; neuron projection; nuclear body; nucleoplasm; nucleus; perikaryon; postsynaptic density; synaptic vesicle | GTP binding GTPase activity protein self-association ubiquitin protein ligase activity zinc ion binding | Rattus norvegicus | Cell projection Cytoplasm Cytoplasmic vesicle Endosome GTP-binding Membrane Metal-binding Neurogenesis Nucleotide-binding Nucleus Reference proteome Synapse Transferase Transmembrane Transmembrane helix Ubl conjugation Ubl conjugation pathway Zinc Zinc-finger | MPRPVLSVTA | MPRPVLSVTAFCHRLGKRESKRSFMGNSSNSWSHASFPKLELGLGQRPSPPRESPTCSICLERLREPISLDCGHDFCIRCFSTHRIPGCELPCCPECRKICKQKKGLRSLGERMKLLPQRPLPPALQETCAVRAERLLLVRINASGGLILRMGAINRCLKHPLARDTPVCLLAVLGEQHSGKSFLLDHLLRGLPGLESGDSTRPRAEGSLPGIRWGANGLTRGIWMWSHPFLLGKEGKKVAVFLVDTGDVMSPELSRETRVKLCALTMMLSSYQILNTSQELKDTDLGYLEMFVHVAEVMGKHYGMVPIQHLDLLVRDSSHHNKSGQGHVGDILQKLSGKYPKVQELLLGKRARCYLLPAPERQWVNKGQASPGGNTEDDFSHHFRAYISDVLSTAPQHAKSRCQGYWSEGRAMARGDRRLLTGQQLAQEIKNLSGWMGKSGPSFSSPDEMAAQLHDLRKVEAAKKEFEEYVRQQDIATKRIFSALRVLPDTMRNLLSTQKDAILARHGVALLCKEREQTLEALEAELQAEAKAFMDSYTMRFCGHLAAVGGAVGAGLMGLAGGVVGAGMAAAALAAEAGMVAAGAAVGATGAAVVGGGVGAGLAATVGCMEKEEDERVQGGDREPLLQEE | embryonic brain development endoplasmic reticulum organization G1 to G0 transition involved in cell differentiation neuron differentiation positive regulation of glial cell differentiation positive regulation of neuron differentiation protein autoubiquitination protein homooligomerization regulation of cell cycle response to hydroperoxide cell body; cytoplasm; endosome; membrane; neuron projection; nuclear body; nucleoplasm; nucleus; perikaryon; postsynaptic density; synaptic vesicle GTP binding GTPase activity protein self-association ubiquitin protein ligase activity zinc ion binding Rattus norvegicus Cell projection Cytoplasm Cytoplasmic vesicle Endosome GTP-binding Membrane Metal-binding Neurogenesis Nucleotide-binding Nucleus Reference proteome Synapse Transferase Transmembrane Transmembrane helix Ubl conjugation Ubl conjugation pathway Zinc Zinc-finger MPRPVLSVTA MPRPVLSVTAFCHRLGKRESKRSFMGNSSNSWSHASFPKLELGLGQRPSPPRESPTCSICLERLREPISLDCGHDFCIRCFSTHRIPGCELPCCPECRKICKQKKGLRSLGERMKLLPQRPLPPALQETCAVRAERLLLVRINASGGLILRMGAINRCLKHPLARDTPVCLLAVLGEQHSGKSFLLDHLLRGLPGLESGDSTRPRAEGSLPGIRWGANGLTRGIWMWSHPFLLGKEGKKVAVFLVDTGDVMSPELSRETRVKLCALTMMLSSYQILNTSQELKDTDLGYLEMFVHVAEVMGKHYGMVPIQHLDLLVRDSSHHNKSGQGHVGDILQKLSGKYPKVQELLLGKRARCYLLPAPERQWVNKGQASPGGNTEDDFSHHFRAYISDVLSTAPQHAKSRCQGYWSEGRAMARGDRRLLTGQQLAQEIKNLSGWMGKSGPSFSSPDEMAAQLHDLRKVEAAKKEFEEYVRQQDIATKRIFSALRVLPDTMRNLLSTQKDAILARHGVALLCKEREQTLEALEAELQAEAKAFMDSYTMRFCGHLAAVGGAVGAGLMGLAGGVVGAGMAAAALAAEAGMVAAGAAVGATGAAVVGGGVGAGLAATVGCMEKEEDERVQGGDREPLLQEE |
atrial cardiac muscle cell development heart trabecula formation negative regulation of apoptotic process negative regulation of calcineurin-NFAT signaling cascade negative regulation of transcription by RNA polymerase II osteoblast differentiation regulation of transcription by RNA polymerase II response to hormone ventricular cardiac muscle cell development | M band; nucleus; Z disc | bHLH transcription factor binding identical protein binding metal ion binding transcription coregulator activity transcription corepressor activity transcription factor binding | Mus musculus | Cytoplasm Isopeptide bond LIM domain Metal-binding Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | MTERFDCHHC | MTERFDCHHCNESLYGKKYILKEENPHCVACFEELYANTCEECGTPIGCDCKDLSYKDRHWHEGCFHCSRCGSSLVDKPFAAKEEQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFTCQRCQQPIGTKSFIPKENQNFCVPCYEKQYALQCVQCKKPITTGGVTYREQPWHKECFVCTACKKQLSGQRFTARDEFPYCLTCFCDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI | atrial cardiac muscle cell development heart trabecula formation negative regulation of apoptotic process negative regulation of calcineurin-NFAT signaling cascade negative regulation of transcription by RNA polymerase II osteoblast differentiation regulation of transcription by RNA polymerase II response to hormone ventricular cardiac muscle cell development M band; nucleus; Z disc bHLH transcription factor binding identical protein binding metal ion binding transcription coregulator activity transcription corepressor activity transcription factor binding Mus musculus Cytoplasm Isopeptide bond LIM domain Metal-binding Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger MTERFDCHHC MTERFDCHHCNESLYGKKYILKEENPHCVACFEELYANTCEECGTPIGCDCKDLSYKDRHWHEGCFHCSRCGSSLVDKPFAAKEEQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFTCQRCQQPIGTKSFIPKENQNFCVPCYEKQYALQCVQCKKPITTGGVTYREQPWHKECFVCTACKKQLSGQRFTARDEFPYCLTCFCDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI |
proteasomal protein catabolic process ubiquitin-dependent protein catabolic process | cytoplasm; cytosol; nucleoplasm; nucleus; proteasome complex; proteasome core complex; proteasome core complex, alpha-subunit complex; synapse | ubiquitin protein ligase binding | Mus musculus | 3D-structure Acetylation Cytoplasm Direct protein sequencing Nucleus Phosphoprotein Proteasome Reference proteome | MSSIGTGYDL | MSSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSAVRPFGCSFMLGSYSANDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMTCRDVVKEVAKIIYIVHDEVKDKAFELELSWVGELTKGRHEIVPKDIREEAEKYAKESLKEEDESDDDNM | proteasomal protein catabolic process ubiquitin-dependent protein catabolic process cytoplasm; cytosol; nucleoplasm; nucleus; proteasome complex; proteasome core complex; proteasome core complex, alpha-subunit complex; synapse ubiquitin protein ligase binding Mus musculus 3D-structure Acetylation Cytoplasm Direct protein sequencing Nucleus Phosphoprotein Proteasome Reference proteome MSSIGTGYDL MSSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSAVRPFGCSFMLGSYSANDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMTCRDVVKEVAKIIYIVHDEVKDKAFELELSWVGELTKGRHEIVPKDIREEAEKYAKESLKEEDESDDDNM |
endosome to lysosome transport intracellular protein transport organelle assembly organelle localization positive regulation of receptor localization to synapse positive regulation of T cell mediated cytotoxicity regulation of protein localization to plasma membrane vesicle docking vesicle fusion vesicle-mediated transport | azurophil granule; early endosome; early endosome membrane; endocytic vesicle; endomembrane system; endosome; immunological synapse; late endosome; late endosome membrane; lysosomal membrane; lysosome; perinuclear region of cytoplasm; plasma membrane; recycling endosome; SNARE complex; synaptic vesicle; synaptic vesicle membrane; tertiary granule; vesicle | chloride channel inhibitor activity protein-containing complex binding SNAP receptor activity SNARE binding syntaxin binding | Mus musculus | 3D-structure Acetylation Coiled coil Endosome Iron Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix | MSYTPGIGGD | MSYTPGIGGDSAQLAQRISSNIQKITQCSVEIQRTLNQLGTPQDSPELRQLLQQKQQYTNQLAKETDKYIKEFGSLPTTPSEQRQRKIQKDRLVAEFTTSLTNFQKAQRQAAEREKEFVARVRASSRVSGGFPEDSSKEKNLVSWESQTQPQVQVQDEEITEDDLRLIHERESSIRQLEADIMDINEIFKDLGMMIHEQGDMIDSIEANVESAEVHVQQANQQLSRAADYQRKSRKTLCIIIFILVVRIVIICLIVWGLKG | endosome to lysosome transport intracellular protein transport organelle assembly organelle localization positive regulation of receptor localization to synapse positive regulation of T cell mediated cytotoxicity regulation of protein localization to plasma membrane vesicle docking vesicle fusion vesicle-mediated transport azurophil granule; early endosome; early endosome membrane; endocytic vesicle; endomembrane system; endosome; immunological synapse; late endosome; late endosome membrane; lysosomal membrane; lysosome; perinuclear region of cytoplasm; plasma membrane; recycling endosome; SNARE complex; synaptic vesicle; synaptic vesicle membrane; tertiary granule; vesicle chloride channel inhibitor activity protein-containing complex binding SNAP receptor activity SNARE binding syntaxin binding Mus musculus 3D-structure Acetylation Coiled coil Endosome Iron Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix MSYTPGIGGD MSYTPGIGGDSAQLAQRISSNIQKITQCSVEIQRTLNQLGTPQDSPELRQLLQQKQQYTNQLAKETDKYIKEFGSLPTTPSEQRQRKIQKDRLVAEFTTSLTNFQKAQRQAAEREKEFVARVRASSRVSGGFPEDSSKEKNLVSWESQTQPQVQVQDEEITEDDLRLIHERESSIRQLEADIMDINEIFKDLGMMIHEQGDMIDSIEANVESAEVHVQQANQQLSRAADYQRKSRKTLCIIIFILVVRIVIICLIVWGLKG |
neurotransmitter secretion synaptic vesicle clustering synaptic vesicle cycle | extrinsic component of synaptic vesicle membrane; glutamatergic synapse; postsynaptic density; presynapse; synapse; synaptic vesicle; synaptic vesicle membrane | ATP binding | Rattus norvegicus | ATP-binding Calcium Cytoplasmic vesicle Membrane Nucleotide-binding Phosphoprotein Reference proteome Synapse | MNFLRRRLSD | MNFLRRRLSDSSFVANLPNGYMPDLQRPESSSSSPASPATERRHPQPLAASFSSPGSSLFSSFSSAMKQTPQAPTGLMEPPTPVTPVVQRPRILLVIDDAHTDWSKYFHGKKVNGDIEIRVEQAEFSELNLAAYVTGGCMVDMQVVRNGTKIVRSFKPDFILVRQHAYSMALAEDYRSLVIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSLGPEKFPLVEQTFFPNHKPMLTAPNFPVVIKLGHAHAGMGKIKVENQHDYQDITSVVAMAKTYATTEAFIDSKYDIRIQKIGSNYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDSCSEMFGGLDICAVKAVHSKNGRDYIIEVMDSSMPLIGEHVEEDKQLMADLVVSKMSQLLVPGASVPSPLRPWGPQTKSAKSPGQGQLGPLLGQPQPRPPPQGGPRQAQSPQPPRSRSPSQQRLSPQGQQPVSPQSGSPQQQRSPGSPQLSRASGGSSPNQASKPTASLSSHTRPPVQGRSTSQQGEEPQKTASPHPHLNKSQSLTNSLSTSDTSHRGTPSEDEAKAETIRNLRKSFASLFSD | neurotransmitter secretion synaptic vesicle clustering synaptic vesicle cycle extrinsic component of synaptic vesicle membrane; glutamatergic synapse; postsynaptic density; presynapse; synapse; synaptic vesicle; synaptic vesicle membrane ATP binding Rattus norvegicus ATP-binding Calcium Cytoplasmic vesicle Membrane Nucleotide-binding Phosphoprotein Reference proteome Synapse MNFLRRRLSD MNFLRRRLSDSSFVANLPNGYMPDLQRPESSSSSPASPATERRHPQPLAASFSSPGSSLFSSFSSAMKQTPQAPTGLMEPPTPVTPVVQRPRILLVIDDAHTDWSKYFHGKKVNGDIEIRVEQAEFSELNLAAYVTGGCMVDMQVVRNGTKIVRSFKPDFILVRQHAYSMALAEDYRSLVIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSLGPEKFPLVEQTFFPNHKPMLTAPNFPVVIKLGHAHAGMGKIKVENQHDYQDITSVVAMAKTYATTEAFIDSKYDIRIQKIGSNYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDSCSEMFGGLDICAVKAVHSKNGRDYIIEVMDSSMPLIGEHVEEDKQLMADLVVSKMSQLLVPGASVPSPLRPWGPQTKSAKSPGQGQLGPLLGQPQPRPPPQGGPRQAQSPQPPRSRSPSQQRLSPQGQQPVSPQSGSPQQQRSPGSPQLSRASGGSSPNQASKPTASLSSHTRPPVQGRSTSQQGEEPQKTASPHPHLNKSQSLTNSLSTSDTSHRGTPSEDEAKAETIRNLRKSFASLFSD |
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled serotonin receptor signaling pathway negative regulation of insulin secretion | cell body; dendrite; heterotrimeric G-protein complex; membrane; plasma membrane | adenylate cyclase inhibitor activity G protein-coupled receptor binding G protein-coupled serotonin receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity metal ion binding | Mus musculus | GTP-binding Lipoprotein Magnesium Membrane Metal-binding Myristate Nucleotide-binding Palmitate Reference proteome Transducer | MGCRQSSEEK | MGCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLDACKEYKPLIIYNAIDSLTRIIRALAALKIDFHNPDRAYDAVQLFALTGPAESKGEITPELLGVMRRLWADPGAQACFGRSSEYHLEDNAAYYLNDLERIAAPDYIPTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLAEKIRRIPLSVCFPEYKGQNTYEEAAVYIQRQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled serotonin receptor signaling pathway negative regulation of insulin secretion cell body; dendrite; heterotrimeric G-protein complex; membrane; plasma membrane adenylate cyclase inhibitor activity G protein-coupled receptor binding G protein-coupled serotonin receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity metal ion binding Mus musculus GTP-binding Lipoprotein Magnesium Membrane Metal-binding Myristate Nucleotide-binding Palmitate Reference proteome Transducer MGCRQSSEEK MGCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLDACKEYKPLIIYNAIDSLTRIIRALAALKIDFHNPDRAYDAVQLFALTGPAESKGEITPELLGVMRRLWADPGAQACFGRSSEYHLEDNAAYYLNDLERIAAPDYIPTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLAEKIRRIPLSVCFPEYKGQNTYEEAAVYIQRQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC |
apoptotic process cell cycle cellular response to forskolin negative regulation of apoptotic process negative regulation of insulin secretion involved in cellular response to glucose stimulus protein phosphorylation regulation of mitotic cell cycle | cytoplasm | ATP binding protein serine kinase activity protein serine/threonine kinase activity | Rattus norvegicus | Apoptosis ATP-binding Cell cycle Cytoplasm Kinase Nucleotide-binding Phosphoprotein Proto-oncogene Reference proteome Serine/threonine-protein kinase Transferase Ubl conjugation | MLLSKFGSLA | MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKVYQVGAVLGSGGFGTVYAGSRIADGLPVAVKHVVKERVTEWGSLGGMAVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGFLLVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHNCGVVHRDIKDENLLVDLRSGELKLIDFGSGAVLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVCGDIPFEQDEEILRGRLFFRRRVSPECQQLIEWCLSLRPSERPSLDQIAAHPWMLGTEGSVPENCDLRLCALDTDDGASTTSSSESL | apoptotic process cell cycle cellular response to forskolin negative regulation of apoptotic process negative regulation of insulin secretion involved in cellular response to glucose stimulus protein phosphorylation regulation of mitotic cell cycle cytoplasm ATP binding protein serine kinase activity protein serine/threonine kinase activity Rattus norvegicus Apoptosis ATP-binding Cell cycle Cytoplasm Kinase Nucleotide-binding Phosphoprotein Proto-oncogene Reference proteome Serine/threonine-protein kinase Transferase Ubl conjugation MLLSKFGSLA MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKVYQVGAVLGSGGFGTVYAGSRIADGLPVAVKHVVKERVTEWGSLGGMAVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGFLLVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHNCGVVHRDIKDENLLVDLRSGELKLIDFGSGAVLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVCGDIPFEQDEEILRGRLFFRRRVSPECQQLIEWCLSLRPSERPSLDQIAAHPWMLGTEGSVPENCDLRLCALDTDDGASTTSSSESL |
cellular response to ionizing radiation DNA damage response DNA repair DNA strand resection involved in replication fork processing homologous recombination mitotic G2/M transition checkpoint negative regulation of apoptotic process negative regulation of protein export from nucleus positive regulation of apoptotic process positive regulation of cell cycle protein K6-linked ubiquitination protein polyubiquitination regulation of DNA damage checkpoint regulation of DNA repair regulation of phosphorylation | BRCA1-A complex; BRCA1-B complex; BRCA1-BARD1 complex; BRCA1-C complex; cytoplasm; cytoplasmic ribonucleoprotein granule; nuclear speck; nuclear ubiquitin ligase complex; nucleoplasm; nucleus | metal ion binding protein heterodimerization activity protein homodimerization activity RNA binding ubiquitin-protein transferase activity | Mus musculus | ANK repeat Cytoplasm DNA damage DNA repair Isopeptide bond Metal-binding Nucleus Phosphoprotein Reference proteome Repeat Transferase Ubl conjugation Ubl conjugation pathway Zinc Zinc-finger | MPRRPPRVCS | MPRRPPRVCSGNQPAPVPAMEPATDGLWAHSRAALARLEKLLRCSRCANILKEPVCLGGCEHIFCSGCISDCVGSGCPVCYTPAWILDLKINRQLDSMIQLSSKLQNLLHDNKDSKDNTSRASLFGDAERKKNSIKMWFSPRSKKVRYVVTKVSVQTQPQKAKDDKAQEASMYEFVSATPPVAVPKSAKTASRTSAKKHPKKSVAKINREENLRPETKDSRFDSKEELKEEKVVSCSQIPVMERPRVNGEIDLLASGSVVEPECSGSLTEVSLPLAEHIVSPDTVSKNEETPEKKVCVKDLRSGGSNGNRKGCHRPTTSTSDSCGSNIPSTSRGIGEPALLAENVVLVDCSSLPSGQLQVDVTLRRKSNASDDPLSLSPGTPPPLLNNSTHRQMMSSPSTVKLSSGMPARKRNHRGETLLHIASIKGDIPSVEYLLQNGNDPNVKDHAGWTPLHEACSHGHLKVVELLLQHNALVNTPGYQNDSPLHDAVKSGHIDIVKVLLSHGASRNAVNIFGVRPVDYTDNENIRSLLLLPEENESFSTSQCSIVNTGQRKNGPLVFIGSGLSSQQQKMLSKLETVLKAKKCMEFDSTVTHVIVPDEEAQSTLKCMLGILSGCWILKFDWVKACLDSKVREQEEKYEVPGGPQRSRLNREQLLPKLFDGCYFFLGGNFKHHPRDDLLKLIAAAGGKVLSRKPKPDSDVTQTINTVAYHAKPESDQRFCTQYIVYEDLFNCHPERVRQGKVWMAPSTWLISCIMAFELLPLDS | cellular response to ionizing radiation DNA damage response DNA repair DNA strand resection involved in replication fork processing homologous recombination mitotic G2/M transition checkpoint negative regulation of apoptotic process negative regulation of protein export from nucleus positive regulation of apoptotic process positive regulation of cell cycle protein K6-linked ubiquitination protein polyubiquitination regulation of DNA damage checkpoint regulation of DNA repair regulation of phosphorylation BRCA1-A complex; BRCA1-B complex; BRCA1-BARD1 complex; BRCA1-C complex; cytoplasm; cytoplasmic ribonucleoprotein granule; nuclear speck; nuclear ubiquitin ligase complex; nucleoplasm; nucleus metal ion binding protein heterodimerization activity protein homodimerization activity RNA binding ubiquitin-protein transferase activity Mus musculus ANK repeat Cytoplasm DNA damage DNA repair Isopeptide bond Metal-binding Nucleus Phosphoprotein Reference proteome Repeat Transferase Ubl conjugation Ubl conjugation pathway Zinc Zinc-finger MPRRPPRVCS MPRRPPRVCSGNQPAPVPAMEPATDGLWAHSRAALARLEKLLRCSRCANILKEPVCLGGCEHIFCSGCISDCVGSGCPVCYTPAWILDLKINRQLDSMIQLSSKLQNLLHDNKDSKDNTSRASLFGDAERKKNSIKMWFSPRSKKVRYVVTKVSVQTQPQKAKDDKAQEASMYEFVSATPPVAVPKSAKTASRTSAKKHPKKSVAKINREENLRPETKDSRFDSKEELKEEKVVSCSQIPVMERPRVNGEIDLLASGSVVEPECSGSLTEVSLPLAEHIVSPDTVSKNEETPEKKVCVKDLRSGGSNGNRKGCHRPTTSTSDSCGSNIPSTSRGIGEPALLAENVVLVDCSSLPSGQLQVDVTLRRKSNASDDPLSLSPGTPPPLLNNSTHRQMMSSPSTVKLSSGMPARKRNHRGETLLHIASIKGDIPSVEYLLQNGNDPNVKDHAGWTPLHEACSHGHLKVVELLLQHNALVNTPGYQNDSPLHDAVKSGHIDIVKVLLSHGASRNAVNIFGVRPVDYTDNENIRSLLLLPEENESFSTSQCSIVNTGQRKNGPLVFIGSGLSSQQQKMLSKLETVLKAKKCMEFDSTVTHVIVPDEEAQSTLKCMLGILSGCWILKFDWVKACLDSKVREQEEKYEVPGGPQRSRLNREQLLPKLFDGCYFFLGGNFKHHPRDDLLKLIAAAGGKVLSRKPKPDSDVTQTINTVAYHAKPESDQRFCTQYIVYEDLFNCHPERVRQGKVWMAPSTWLISCIMAFELLPLDS |
lactate transmembrane transport monocarboxylic acid transport plasma membrane lactate transport pyruvate transmembrane transport | basolateral plasma membrane; cytosol; glutamatergic synapse; hippocampal mossy fiber to CA3 synapse; nucleoplasm; parallel fiber to Purkinje cell synapse; plasma membrane; postsynaptic density membrane; Schaffer collateral - CA1 synapse | identical protein binding lactate transmembrane transporter activity monocarboxylic acid transmembrane transporter activity pyruvate transmembrane transporter activity symporter activity | Mus musculus | Cell membrane Cytoplasm Membrane Reference proteome Symport Transmembrane Transmembrane helix Transport | MPSEPSAPLP | MPSEPSAPLPQPLPPDGGWGWVVVCASFISIGFSYAFPKAVTVFFKDIQEIFNTTSSQIAWISSIMLAVMYAGGPISSVLVNNYGSRPVVIVGGLLCCIGMILASYSNSVIELYLTVGFIGGLGLAFNLQPALTIIGKYFYRRRPLANGCAMAGSPVFLSTLAPFNQYLFNNYGWKGSFLILGGIFLHSCVAGCLMRPVGPSPNTKKSKSKVGSRHDSTLKKASKVSTAQKVNRFLDFSLFMHRGFLIYLSGNVILFLGIFAPIIFLAQYAKHIGVDDYNSAFLLSVMAFIDMFARPSVGLIANTSLIRPRIQYLFSSAIIFTGICHLLCPLATTYSALVVYVVFFGLGFGSISSLLFECLMDIVGATRFSSAVGLTTIVECCPVLFGPPLAGKLLDITGEYKYLYIASGTVVLVSGTYLLIGNAINYRLLDKERKREKAKKKKSASHASREMEALNRSKQDEVTVKASNAHNPPSDRDKESNI | lactate transmembrane transport monocarboxylic acid transport plasma membrane lactate transport pyruvate transmembrane transport basolateral plasma membrane; cytosol; glutamatergic synapse; hippocampal mossy fiber to CA3 synapse; nucleoplasm; parallel fiber to Purkinje cell synapse; plasma membrane; postsynaptic density membrane; Schaffer collateral - CA1 synapse identical protein binding lactate transmembrane transporter activity monocarboxylic acid transmembrane transporter activity pyruvate transmembrane transporter activity symporter activity Mus musculus Cell membrane Cytoplasm Membrane Reference proteome Symport Transmembrane Transmembrane helix Transport MPSEPSAPLP MPSEPSAPLPQPLPPDGGWGWVVVCASFISIGFSYAFPKAVTVFFKDIQEIFNTTSSQIAWISSIMLAVMYAGGPISSVLVNNYGSRPVVIVGGLLCCIGMILASYSNSVIELYLTVGFIGGLGLAFNLQPALTIIGKYFYRRRPLANGCAMAGSPVFLSTLAPFNQYLFNNYGWKGSFLILGGIFLHSCVAGCLMRPVGPSPNTKKSKSKVGSRHDSTLKKASKVSTAQKVNRFLDFSLFMHRGFLIYLSGNVILFLGIFAPIIFLAQYAKHIGVDDYNSAFLLSVMAFIDMFARPSVGLIANTSLIRPRIQYLFSSAIIFTGICHLLCPLATTYSALVVYVVFFGLGFGSISSLLFECLMDIVGATRFSSAVGLTTIVECCPVLFGPPLAGKLLDITGEYKYLYIASGTVVLVSGTYLLIGNAINYRLLDKERKREKAKKKKSASHASREMEALNRSKQDEVTVKASNAHNPPSDRDKESNI |
establishment of skin barrier intrinsic apoptotic signaling pathway in response to DNA damage keratinization keratinocyte development keratinocyte differentiation keratinocyte proliferation negative regulation of innate immune response negative regulation of keratinocyte proliferation negative regulation of stem cell proliferation negative regulation of transcription by RNA polymerase II positive regulation of cell growth positive regulation of epidermal cell differentiation positive regulation of protein export from nucleus protein export from nucleus protein kinase A signaling regulation of cell cycle regulation of epidermal cell division release of cytochrome c from mitochondria signal transduction skin development stem cell proliferation | cytoplasm; cytosol; extracellular region; nucleus | identical protein binding phosphoprotein binding phosphoserine residue binding protein kinase binding protein sequestering activity | Mus musculus | Cytoplasm Direct protein sequencing Nucleus Phosphoprotein Reference proteome Secreted Ubl conjugation | MERASLIQKA | MERASLIQKAKLAEQAERYEDMAAFMKSAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEEGSEEKGPEVKEYREKVETELRGVCDTVLGLLDSHLIKGAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTADSAGEEGGEAPEEPQS | establishment of skin barrier intrinsic apoptotic signaling pathway in response to DNA damage keratinization keratinocyte development keratinocyte differentiation keratinocyte proliferation negative regulation of innate immune response negative regulation of keratinocyte proliferation negative regulation of stem cell proliferation negative regulation of transcription by RNA polymerase II positive regulation of cell growth positive regulation of epidermal cell differentiation positive regulation of protein export from nucleus protein export from nucleus protein kinase A signaling regulation of cell cycle regulation of epidermal cell division release of cytochrome c from mitochondria signal transduction skin development stem cell proliferation cytoplasm; cytosol; extracellular region; nucleus identical protein binding phosphoprotein binding phosphoserine residue binding protein kinase binding protein sequestering activity Mus musculus Cytoplasm Direct protein sequencing Nucleus Phosphoprotein Reference proteome Secreted Ubl conjugation MERASLIQKA MERASLIQKAKLAEQAERYEDMAAFMKSAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEEGSEEKGPEVKEYREKVETELRGVCDTVLGLLDSHLIKGAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTADSAGEEGGEAPEEPQS |
cell surface receptor signaling pathway cytokine-mediated signaling pathway oncostatin-M-mediated signaling pathway positive regulation of cell population proliferation response to cytokine | apical plasma membrane; external side of plasma membrane; oncostatin-M receptor complex; plasma membrane; receptor complex | ciliary neurotrophic factor receptor binding cytokine binding cytokine receptor activity growth factor binding oncostatin-M receptor activity | Mus musculus | Alternative splicing Disulfide bond Glycoprotein Membrane Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix | MAFSVVLHPA | MAFSVVLHPAFLLAVLSLRASRSEVLEEPLPLTPEIHKVSFQLKLQEVNLEWTVPALTHEELNMIFQIEISRLNISNTIWVENYSTTVKREEAVRWNWTSDIPLECVKHFIRIRALVDDTKSLPQSSWGNWSSWKEVNAKVSVEPDKSLIFPKDKVLEEGSNVTICLMYGQNVYNVSCKLQDEPIHGEQLDSHVSLLKLNNVVFLSDTGTNINCQATKGPKRIFGTVLFVSKVLEEPKNVSCETRDFKTLDCSWEPGVDTTLTWRKQRFQNYTLCESFSKRCEVSNYRNSYTWQITEGSQEMYNFTLTAENQLRKRSVNINFNLTHRVHPKAPQDVTLKIIGATKANMTWKVHSHGNNYTLLCQVKLQYGEVIHEHNVSVHMSANYLFSDLDPDTKYKAFVRCASANHFWKWSDWTQKEFSTPETAPSQALDVWRQVWSENGRRIVTLFWKPLLKSQANGKIISYNIVVENEAKPTESEHYCVWAPALSTNLSLDLQPYKIRITTNNSMGASPESLMVLSNDSGHEEVKEKTIKGIKDAFNISWEPVSGDTMGYVVDWCAHSQDQRCDLQWKNLGPNTTSTTITSDDFKPGVRYNFRIFERSVEHKARLVEKQRGYTQELAPLVNPKVEIPYSTPNSFVLRWPDYDSDFQAGFIKGYLVYVKSKEMQCNQPWERTLLPDNSVLCKYDINGSETKTLTVENLQPESLYEFFVTPYTSAGPGPNETFTKVTTPDARSHMLLQIILPMTLCVLLSIIVCYWKSQWVKEKCYPDIPNPYKSSILSLIKSKKNPHLIMNVKDCIPDVLEVINKAEGSKTQCVGSGKLHIEDVPTKPPIVPTEKDSSGPVPCIFFENFTYDQSAFDSGSHGLIPGPLKDTAHQLGLLAPPNKFQNVLKNDYMKPLVESPTEETSLIYVSQLASPMCGDKDTLATEPPVPVHGSEYKRQMVVPGSLASPSLKEDNSLTSTVLLGQGEQ | cell surface receptor signaling pathway cytokine-mediated signaling pathway oncostatin-M-mediated signaling pathway positive regulation of cell population proliferation response to cytokine apical plasma membrane; external side of plasma membrane; oncostatin-M receptor complex; plasma membrane; receptor complex ciliary neurotrophic factor receptor binding cytokine binding cytokine receptor activity growth factor binding oncostatin-M receptor activity Mus musculus Alternative splicing Disulfide bond Glycoprotein Membrane Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix MAFSVVLHPA MAFSVVLHPAFLLAVLSLRASRSEVLEEPLPLTPEIHKVSFQLKLQEVNLEWTVPALTHEELNMIFQIEISRLNISNTIWVENYSTTVKREEAVRWNWTSDIPLECVKHFIRIRALVDDTKSLPQSSWGNWSSWKEVNAKVSVEPDKSLIFPKDKVLEEGSNVTICLMYGQNVYNVSCKLQDEPIHGEQLDSHVSLLKLNNVVFLSDTGTNINCQATKGPKRIFGTVLFVSKVLEEPKNVSCETRDFKTLDCSWEPGVDTTLTWRKQRFQNYTLCESFSKRCEVSNYRNSYTWQITEGSQEMYNFTLTAENQLRKRSVNINFNLTHRVHPKAPQDVTLKIIGATKANMTWKVHSHGNNYTLLCQVKLQYGEVIHEHNVSVHMSANYLFSDLDPDTKYKAFVRCASANHFWKWSDWTQKEFSTPETAPSQALDVWRQVWSENGRRIVTLFWKPLLKSQANGKIISYNIVVENEAKPTESEHYCVWAPALSTNLSLDLQPYKIRITTNNSMGASPESLMVLSNDSGHEEVKEKTIKGIKDAFNISWEPVSGDTMGYVVDWCAHSQDQRCDLQWKNLGPNTTSTTITSDDFKPGVRYNFRIFERSVEHKARLVEKQRGYTQELAPLVNPKVEIPYSTPNSFVLRWPDYDSDFQAGFIKGYLVYVKSKEMQCNQPWERTLLPDNSVLCKYDINGSETKTLTVENLQPESLYEFFVTPYTSAGPGPNETFTKVTTPDARSHMLLQIILPMTLCVLLSIIVCYWKSQWVKEKCYPDIPNPYKSSILSLIKSKKNPHLIMNVKDCIPDVLEVINKAEGSKTQCVGSGKLHIEDVPTKPPIVPTEKDSSGPVPCIFFENFTYDQSAFDSGSHGLIPGPLKDTAHQLGLLAPPNKFQNVLKNDYMKPLVESPTEETSLIYVSQLASPMCGDKDTLATEPPVPVHGSEYKRQMVVPGSLASPSLKEDNSLTSTVLLGQGEQ |
dendritic spine morphogenesis methylation negative regulation of protein ubiquitination negative regulation of retinoic acid biosynthetic process | cytoplasm; cytosol; nucleus | metal ion binding methyltransferase activity modified amino acid binding protein-arginine N-methyltransferase activity protein-arginine omega-N asymmetric methyltransferase activity protein-arginine omega-N monomethyltransferase activity ribosome binding S-adenosylmethionine-dependent methyltransferase activity | Rattus norvegicus | 3D-structure Acetylation Cytoplasm Metal-binding Methyltransferase Phosphoprotein Reference proteome S-adenosyl-L-methionine Transferase Zinc Zinc-finger | MCSLAAGNGQ | MCSLAAGNGQGAELGPEPLELSDSGDDAGWEDEDADAEPAQGRQHTPCLFCDRLFRSAEETFSHCKLEHQFNIDGMVHKHGLEFYGYIKLINFIRLKNPTVEYMNSIYNPVPWDKDEYLKPVLEDDLLLQFDVEDLYEPVSAPFTYPNGLSENTSAVEKLKLMEARALSAEAALARAREDLQKMKQFAQDFVMNVDVRTCSSTTTIADLQEDEDGVYFSSYGHYGIHEEMLKDKVRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVIAVDQSEILYQAMDIIRLNKLEDTIVLIKGKIEEVSLPVEKVDVIISEWMGYFLLFESMLDSVLYAKSKYLAKGGSVYPDICTISLVAVSDVSKHADRIAFWDDVYGFNMSCMKKAVIPEAVVEVVDHKTLISDPCDIKHIDCHTTSISDLEFSSDFTLRTTKTAMCTAVAGYFDIYFEKNCHNRVVFSTGPQSTKTHWKQTIFLLEKPFPVKAGEALKGKITVHKNKKDPRSLIVTLTLNSSTQTYSLQ | dendritic spine morphogenesis methylation negative regulation of protein ubiquitination negative regulation of retinoic acid biosynthetic process cytoplasm; cytosol; nucleus metal ion binding methyltransferase activity modified amino acid binding protein-arginine N-methyltransferase activity protein-arginine omega-N asymmetric methyltransferase activity protein-arginine omega-N monomethyltransferase activity ribosome binding S-adenosylmethionine-dependent methyltransferase activity Rattus norvegicus 3D-structure Acetylation Cytoplasm Metal-binding Methyltransferase Phosphoprotein Reference proteome S-adenosyl-L-methionine Transferase Zinc Zinc-finger MCSLAAGNGQ MCSLAAGNGQGAELGPEPLELSDSGDDAGWEDEDADAEPAQGRQHTPCLFCDRLFRSAEETFSHCKLEHQFNIDGMVHKHGLEFYGYIKLINFIRLKNPTVEYMNSIYNPVPWDKDEYLKPVLEDDLLLQFDVEDLYEPVSAPFTYPNGLSENTSAVEKLKLMEARALSAEAALARAREDLQKMKQFAQDFVMNVDVRTCSSTTTIADLQEDEDGVYFSSYGHYGIHEEMLKDKVRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVIAVDQSEILYQAMDIIRLNKLEDTIVLIKGKIEEVSLPVEKVDVIISEWMGYFLLFESMLDSVLYAKSKYLAKGGSVYPDICTISLVAVSDVSKHADRIAFWDDVYGFNMSCMKKAVIPEAVVEVVDHKTLISDPCDIKHIDCHTTSISDLEFSSDFTLRTTKTAMCTAVAGYFDIYFEKNCHNRVVFSTGPQSTKTHWKQTIFLLEKPFPVKAGEALKGKITVHKNKKDPRSLIVTLTLNSSTQTYSLQ |
negative regulation of MAPK cascade positive regulation of MAPK cascade Ras protein signal transduction transmembrane receptor protein tyrosine kinase signaling pathway | cytoplasm | transmembrane receptor protein tyrosine kinase adaptor activity | Mus musculus | Phosphoprotein Reference proteome | MVRMEEPAVK | MVRMEEPAVKQGFLHLQQQQTFGKKWRRFAAVLYGESGCALARLELQDVPEKTRRGEATRKVVRLSDCLRVAEVGSEASSPRDTSAFILETKERLYLLAAPSAERSDWIQAICLLAFPGQRKGSPGLEEKSGSPCMEENELYSSSTTGLCKEYMVTIRPTEASERCRLRGSYTLRTGVSALELWGGPEPGTQLYDWPYRFLRRFGRDKATFSFEAGRRCLSGEGNFEFETRHGNEIFQALEKVIAVQKNATPSGPPSLPATGPMMPTVLPRPESPYSRPHDSLPSPSPGTLVPGMRPGAPEGEYAVPFDTVAHSLRKSFRGLLTGPPPHLPDPLYDSIQEDPGAPLPDHIYDEPEGVAALSLYDRTQRPSGETWREQATADGGPSSLQQDSSVPDWPQATEYDNVILKKGPK | negative regulation of MAPK cascade positive regulation of MAPK cascade Ras protein signal transduction transmembrane receptor protein tyrosine kinase signaling pathway cytoplasm transmembrane receptor protein tyrosine kinase adaptor activity Mus musculus Phosphoprotein Reference proteome MVRMEEPAVK MVRMEEPAVKQGFLHLQQQQTFGKKWRRFAAVLYGESGCALARLELQDVPEKTRRGEATRKVVRLSDCLRVAEVGSEASSPRDTSAFILETKERLYLLAAPSAERSDWIQAICLLAFPGQRKGSPGLEEKSGSPCMEENELYSSSTTGLCKEYMVTIRPTEASERCRLRGSYTLRTGVSALELWGGPEPGTQLYDWPYRFLRRFGRDKATFSFEAGRRCLSGEGNFEFETRHGNEIFQALEKVIAVQKNATPSGPPSLPATGPMMPTVLPRPESPYSRPHDSLPSPSPGTLVPGMRPGAPEGEYAVPFDTVAHSLRKSFRGLLTGPPPHLPDPLYDSIQEDPGAPLPDHIYDEPEGVAALSLYDRTQRPSGETWREQATADGGPSSLQQDSSVPDWPQATEYDNVILKKGPK |
aldehyde catabolic process cellular detoxification of aldehyde D-glucuronate catabolic process daunorubicin metabolic process doxorubicin metabolic process glucuronate catabolic process to xylulose 5-phosphate L-ascorbic acid biosynthetic process lipid metabolic process | apical plasma membrane; cytosol; synapse | alditol:NADP+ 1-oxidoreductase activity allyl-alcohol dehydrogenase activity glucuronolactone reductase activity glycerol dehydrogenase activity L-glucuronate reductase activity methylglyoxal reductase (NADPH-dependent, acetol producing) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor | Cricetulus griseus | Acetylation Cell membrane Cytoplasm Lipid metabolism Membrane NADP Oxidoreductase Phosphoprotein Reference proteome | MASCVLLHTG | MASCVLLHTGQKMPLIGLGTWKSNPGQVKAAIKYALSVGYRHIDCAAVYGNEIEIGEALKENVGPGKAVPREELFVTSKLWNTKHHPEDVEAALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNDDGTIRYDSTHYKETWKALEALVAKGLVKALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPVVLALAEKHGRSPAQILLRWQVQRKVVCIPKSITPSRILQNIQVFDFTFSPEEMKQLDALNKHWRYIVPMITVDGKSVPRDAGHPLYPFNDPY | aldehyde catabolic process cellular detoxification of aldehyde D-glucuronate catabolic process daunorubicin metabolic process doxorubicin metabolic process glucuronate catabolic process to xylulose 5-phosphate L-ascorbic acid biosynthetic process lipid metabolic process apical plasma membrane; cytosol; synapse alditol:NADP+ 1-oxidoreductase activity allyl-alcohol dehydrogenase activity glucuronolactone reductase activity glycerol dehydrogenase activity L-glucuronate reductase activity methylglyoxal reductase (NADPH-dependent, acetol producing) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor Cricetulus griseus Acetylation Cell membrane Cytoplasm Lipid metabolism Membrane NADP Oxidoreductase Phosphoprotein Reference proteome MASCVLLHTG MASCVLLHTGQKMPLIGLGTWKSNPGQVKAAIKYALSVGYRHIDCAAVYGNEIEIGEALKENVGPGKAVPREELFVTSKLWNTKHHPEDVEAALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNDDGTIRYDSTHYKETWKALEALVAKGLVKALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPVVLALAEKHGRSPAQILLRWQVQRKVVCIPKSITPSRILQNIQVFDFTFSPEEMKQLDALNKHWRYIVPMITVDGKSVPRDAGHPLYPFNDPY |
carbohydrate metabolic process chondroitin sulfate biosynthetic process gastrulation with mouth forming second glycosaminoglycan biosynthetic process heparan sulfate proteoglycan biosynthetic process neuron development protein hexamerization UDP-glucuronate biosynthetic process | nucleoplasm; nucleus | identical protein binding NAD binding UDP-glucose 6-dehydrogenase activity | Mus musculus | Acetylation Allosteric enzyme Carbohydrate metabolism NAD Oxidoreductase Phosphoprotein Reference proteome | MVEIKKICCI | MVEIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNEARINAWNSPTLPIYEPGLKEVVESCRGKNLFFSTNIDDAIREADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGDETPEGQKAVRALCAVYEHWVPKEKILTTNTWSSELSKLAANAFLAQRISSINSISALCEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYWQQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDEGAHLHIYDPKVPREQIVVDLSHPGVSADDQVSRLVTISKDPYEACDGAHALVICTEWDMFKELDYERIHKKMLKPAFIFDGRRVLDGLHSELQTIGFQIETIGKKVSSKRIPYTPGEIPKFSLQDPPNKKPKV | carbohydrate metabolic process chondroitin sulfate biosynthetic process gastrulation with mouth forming second glycosaminoglycan biosynthetic process heparan sulfate proteoglycan biosynthetic process neuron development protein hexamerization UDP-glucuronate biosynthetic process nucleoplasm; nucleus identical protein binding NAD binding UDP-glucose 6-dehydrogenase activity Mus musculus Acetylation Allosteric enzyme Carbohydrate metabolism NAD Oxidoreductase Phosphoprotein Reference proteome MVEIKKICCI MVEIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNEARINAWNSPTLPIYEPGLKEVVESCRGKNLFFSTNIDDAIREADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGDETPEGQKAVRALCAVYEHWVPKEKILTTNTWSSELSKLAANAFLAQRISSINSISALCEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYWQQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDEGAHLHIYDPKVPREQIVVDLSHPGVSADDQVSRLVTISKDPYEACDGAHALVICTEWDMFKELDYERIHKKMLKPAFIFDGRRVLDGLHSELQTIGFQIETIGKKVSSKRIPYTPGEIPKFSLQDPPNKKPKV |
angiogenesis camera-type eye development erythrocyte differentiation hemopoiesis positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II T cell differentiation | cytoplasm; nucleoplasm; nucleus; transcription regulator complex | chromatin binding DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA binding | Mus musculus | Activator DNA-binding Homeobox Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MMATQTLSID | MMATQTLSIDSYQDGQQMQVVTELKTEQDPNCSDPDAEGVSPPPIESQTPMDADKQAIYRHPLFPLLALLFEKCEQSTQGSEGTTSASFDVDIENFVRKQEKDGKPFFCEDPETDNLMVKAIQVLRIHLLELEKVNELCKDFCSRYIACLKTKMNSETLLSGEPGSPYSPVQSQQIQSAITGTLSPQGIVVPASALQQGNVTMATVAGGTVYQPVTVVTPQGQVVTQALSPGTIRIQNSQLQLQLNQDLSILHQEDGSSKNKRGVLPKHATNVMRSWLFQHIGHPYPTEDEKKQIAAQTNLTLLQVNNWFINARRRILQPMLDSSCSETPKTKKKPAQNRPVQRFWPDSLASGVAQATPSELAMSEGAVVTITTPVNMNVDSLQSLSSDGATLAVQQVMMAGQSEDESVDSTEDEGGALAPTHISGLVLENSDSLQ | angiogenesis camera-type eye development erythrocyte differentiation hemopoiesis positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II T cell differentiation cytoplasm; nucleoplasm; nucleus; transcription regulator complex chromatin binding DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA binding Mus musculus Activator DNA-binding Homeobox Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation MMATQTLSID MMATQTLSIDSYQDGQQMQVVTELKTEQDPNCSDPDAEGVSPPPIESQTPMDADKQAIYRHPLFPLLALLFEKCEQSTQGSEGTTSASFDVDIENFVRKQEKDGKPFFCEDPETDNLMVKAIQVLRIHLLELEKVNELCKDFCSRYIACLKTKMNSETLLSGEPGSPYSPVQSQQIQSAITGTLSPQGIVVPASALQQGNVTMATVAGGTVYQPVTVVTPQGQVVTQALSPGTIRIQNSQLQLQLNQDLSILHQEDGSSKNKRGVLPKHATNVMRSWLFQHIGHPYPTEDEKKQIAAQTNLTLLQVNNWFINARRRILQPMLDSSCSETPKTKKKPAQNRPVQRFWPDSLASGVAQATPSELAMSEGAVVTITTPVNMNVDSLQSLSSDGATLAVQQVMMAGQSEDESVDSTEDEGGALAPTHISGLVLENSDSLQ |
acyl-CoA metabolic process fatty acid biosynthetic process medium-chain fatty-acyl-CoA metabolic process | mitochondrial matrix; mitochondrion | ATP binding benzoate-CoA ligase activity butyrate-CoA ligase activity decanoate-CoA ligase activity fatty acid ligase activity fatty-acyl-CoA synthase activity metal ion binding | Rattus norvegicus | ATP-binding Fatty acid metabolism Ligase Lipid metabolism Magnesium Metal-binding Mitochondrion Nucleotide-binding Reference proteome Transit peptide | MHWLWKIPRL | MHWLWKIPRLCTFWGTEMFHRTFHMNIKKLMPIQWGHQEVPAKFNFASDVIDHWASLEKAGKRSPGPALWWMNGSGEELKWNFRELSEISKQTANVLTGACGLQRGDRVAVVLPRVPEWWLVTLGCMRSGLVFMPGTTQMKSTDILYRLQSSKARAIVAGDEVVQEVDAVAPDCSFLKIKLLVSEKNREGWLNFKALLKDASPIHQCVETVSQESAAIYFTSGTSGPPKMAEHSHCSLGLKAKMDAGWTGLGPSDTMWTISDTGWILNILGSFLEPWVLGTCIFVHLLPKFDPQTVLKVLSSYPINTLLGAPLIYRMLLQQDLSSYKFPHLHSCFSGGETLLPETLESWKAKTGLEIREIYGQTETGITCRVSRTMKVKPGYLGTAIVPYDVQVIDEQGNVLPPGKEGDMALRVKPIRPIGMFSGYVDNPKKTQANIRGDFWLLGDRGIKDTEGYFHFMGRTDDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPIRREVVKAFVVLAPEFLSHDQDQLTKVLQEHVKSVTAPYKYPRKVEFVLDLPKTITGKIERAKLRAKEWKTSG | acyl-CoA metabolic process fatty acid biosynthetic process medium-chain fatty-acyl-CoA metabolic process mitochondrial matrix; mitochondrion ATP binding benzoate-CoA ligase activity butyrate-CoA ligase activity decanoate-CoA ligase activity fatty acid ligase activity fatty-acyl-CoA synthase activity metal ion binding Rattus norvegicus ATP-binding Fatty acid metabolism Ligase Lipid metabolism Magnesium Metal-binding Mitochondrion Nucleotide-binding Reference proteome Transit peptide MHWLWKIPRL MHWLWKIPRLCTFWGTEMFHRTFHMNIKKLMPIQWGHQEVPAKFNFASDVIDHWASLEKAGKRSPGPALWWMNGSGEELKWNFRELSEISKQTANVLTGACGLQRGDRVAVVLPRVPEWWLVTLGCMRSGLVFMPGTTQMKSTDILYRLQSSKARAIVAGDEVVQEVDAVAPDCSFLKIKLLVSEKNREGWLNFKALLKDASPIHQCVETVSQESAAIYFTSGTSGPPKMAEHSHCSLGLKAKMDAGWTGLGPSDTMWTISDTGWILNILGSFLEPWVLGTCIFVHLLPKFDPQTVLKVLSSYPINTLLGAPLIYRMLLQQDLSSYKFPHLHSCFSGGETLLPETLESWKAKTGLEIREIYGQTETGITCRVSRTMKVKPGYLGTAIVPYDVQVIDEQGNVLPPGKEGDMALRVKPIRPIGMFSGYVDNPKKTQANIRGDFWLLGDRGIKDTEGYFHFMGRTDDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPIRREVVKAFVVLAPEFLSHDQDQLTKVLQEHVKSVTAPYKYPRKVEFVLDLPKTITGKIERAKLRAKEWKTSG |
endocytic recycling heme biosynthetic process hemoglobin biosynthetic process intralumenal vesicle formation late endosome to Golgi transport membrane invagination negative regulation of early endosome to late endosome transport negative regulation of phagocytosis negative regulation of protein catabolic process negative regulation of protein transport negative regulation of viral entry into host cell positive regulation of neuron projection development protein to membrane docking regulation of intracellular protein transport regulation of protein metabolic process regulation of Wnt signaling pathway response to bacterium transferrin transport | clathrin-coated vesicle; cytoplasm; cytosol; early endosome; early endosome membrane; early phagosome; endosome membrane; retromer complex | phosphatidylinositol-3,5-bisphosphate binding phosphatidylinositol-3-phosphate binding phosphatidylinositol-4-phosphate binding phosphatidylinositol-5-phosphate binding protein phosphatase binding retromer complex binding | Mus musculus | Acetylation Cytoplasmic vesicle Endosome Isopeptide bond Lipid-binding Methylation Phosphoprotein Protein transport Reference proteome Transport Ubl conjugation | MAETVADTRR | MAETVADTRRLITKPQNLNDAYGPPSNFLEIDVSNPQTVGVGRGRFTTYEIRVKTNLPIFKLKESTVRRRYSDFEWLRSELERESKVVVPPLPGKAFLRHVPFRGDDGIFDDNFIEERKQGLEQFINKVAGHPLAQNERCLHMFLQDEIIDKSYTPSKIRHA | endocytic recycling heme biosynthetic process hemoglobin biosynthetic process intralumenal vesicle formation late endosome to Golgi transport membrane invagination negative regulation of early endosome to late endosome transport negative regulation of phagocytosis negative regulation of protein catabolic process negative regulation of protein transport negative regulation of viral entry into host cell positive regulation of neuron projection development protein to membrane docking regulation of intracellular protein transport regulation of protein metabolic process regulation of Wnt signaling pathway response to bacterium transferrin transport clathrin-coated vesicle; cytoplasm; cytosol; early endosome; early endosome membrane; early phagosome; endosome membrane; retromer complex phosphatidylinositol-3,5-bisphosphate binding phosphatidylinositol-3-phosphate binding phosphatidylinositol-4-phosphate binding phosphatidylinositol-5-phosphate binding protein phosphatase binding retromer complex binding Mus musculus Acetylation Cytoplasmic vesicle Endosome Isopeptide bond Lipid-binding Methylation Phosphoprotein Protein transport Reference proteome Transport Ubl conjugation MAETVADTRR MAETVADTRRLITKPQNLNDAYGPPSNFLEIDVSNPQTVGVGRGRFTTYEIRVKTNLPIFKLKESTVRRRYSDFEWLRSELERESKVVVPPLPGKAFLRHVPFRGDDGIFDDNFIEERKQGLEQFINKVAGHPLAQNERCLHMFLQDEIIDKSYTPSKIRHA |
B cell differentiation definitive hemopoiesis embryonic camera-type eye morphogenesis embryonic placenta development embryonic process involved in female pregnancy embryonic skeletal system development enucleate erythrocyte differentiation erythrocyte differentiation granulocyte differentiation in utero embryonic development liver development lung development megakaryocyte differentiation monocyte differentiation myeloid progenitor cell differentiation natural killer cell differentiation negative regulation of DNA-templated transcription ossification positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of transcription by RNA polymerase II T cell differentiation trophectodermal cell differentiation | cytosol; nucleoplasm; nucleus; PML body; protein-DNA complex; transcription repressor complex | chromatin binding cis-regulatory region sequence-specific DNA binding DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific double-stranded DNA binding metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II-specific DNA-binding transcription factor binding sequence-specific double-stranded DNA binding | Mus musculus | Acetylation Activator Alternative splicing DNA-binding Isopeptide bond Metal-binding Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | MTAPEKPVKQ | MTAPEKPVKQEEMAALDVDGGGGGGGHGEYLQQQQQQQQQHGNGAAAAAAQDTQPSPLALLAATCSKIGPPSPGDDDEEAAVAAAAGVPAAAAGATGDLASAQLGGAPNRWEVLSATPTTIKDEAGNLVQIPGAATSSGQYVLPLQNLQNQQIFSVAPGSDSSNGTVSNVQYQVIPQIQSTDAQQVQIGFTGSSDNGGINQENSQIQIIPGSNQTLLASGTPPANIQNLIPQTGQVQVQGVAIGGSSFPGQTQVVANVPLGLPGNITFVPINSVDLDSLGLSGSSQTMTAGINADGHLINTGQAMDSSDNSERTGERVSPDVNETNADTDLFVPTSSSSQLPVTIDSTGILQQNTNSLTTTSGQVHSSDLQGNYIQSPVSEETQAQNIQVSTAQPVVQHLQLQDSQQPTSQAQIVQGITPQTIHGVQASGQNISQQALQNLQLQLNPGTFLIQAQTVTPSGQITWQTFQVQGVQNLQNLQIQNTAAQQITLTPVQTLTLGQVAAGGALTSTPVSLSTGQLPNLQTVTVNSIDSTGIQLHPGENADSPADIRIKEEEPDPEEWQLSGDSTLNTNDLTHLRVQVVDEEGDQQHQEGKRLRRVACTCPNCKEGGGRGTNLGKKKQHICHIPGCGKVYGKTSHLRAHLRWHSGERPFICNWMFCGKRFTRSDELQRHRRTHTGEKKFVCPECSKRFMRSDHLAKHIKTHQNKKVIHSSSTVLASVEAGRDDALITAGGTTLILANIQQGSVSGIGTVNTSATSNQDILTNTEIPLQLVTVSGNETME | B cell differentiation definitive hemopoiesis embryonic camera-type eye morphogenesis embryonic placenta development embryonic process involved in female pregnancy embryonic skeletal system development enucleate erythrocyte differentiation erythrocyte differentiation granulocyte differentiation in utero embryonic development liver development lung development megakaryocyte differentiation monocyte differentiation myeloid progenitor cell differentiation natural killer cell differentiation negative regulation of DNA-templated transcription ossification positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of transcription by RNA polymerase II T cell differentiation trophectodermal cell differentiation cytosol; nucleoplasm; nucleus; PML body; protein-DNA complex; transcription repressor complex chromatin binding cis-regulatory region sequence-specific DNA binding DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific double-stranded DNA binding metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II-specific DNA-binding transcription factor binding sequence-specific double-stranded DNA binding Mus musculus Acetylation Activator Alternative splicing DNA-binding Isopeptide bond Metal-binding Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger MTAPEKPVKQ MTAPEKPVKQEEMAALDVDGGGGGGGHGEYLQQQQQQQQQHGNGAAAAAAQDTQPSPLALLAATCSKIGPPSPGDDDEEAAVAAAAGVPAAAAGATGDLASAQLGGAPNRWEVLSATPTTIKDEAGNLVQIPGAATSSGQYVLPLQNLQNQQIFSVAPGSDSSNGTVSNVQYQVIPQIQSTDAQQVQIGFTGSSDNGGINQENSQIQIIPGSNQTLLASGTPPANIQNLIPQTGQVQVQGVAIGGSSFPGQTQVVANVPLGLPGNITFVPINSVDLDSLGLSGSSQTMTAGINADGHLINTGQAMDSSDNSERTGERVSPDVNETNADTDLFVPTSSSSQLPVTIDSTGILQQNTNSLTTTSGQVHSSDLQGNYIQSPVSEETQAQNIQVSTAQPVVQHLQLQDSQQPTSQAQIVQGITPQTIHGVQASGQNISQQALQNLQLQLNPGTFLIQAQTVTPSGQITWQTFQVQGVQNLQNLQIQNTAAQQITLTPVQTLTLGQVAAGGALTSTPVSLSTGQLPNLQTVTVNSIDSTGIQLHPGENADSPADIRIKEEEPDPEEWQLSGDSTLNTNDLTHLRVQVVDEEGDQQHQEGKRLRRVACTCPNCKEGGGRGTNLGKKKQHICHIPGCGKVYGKTSHLRAHLRWHSGERPFICNWMFCGKRFTRSDELQRHRRTHTGEKKFVCPECSKRFMRSDHLAKHIKTHQNKKVIHSSSTVLASVEAGRDDALITAGGTTLILANIQQGSVSGIGTVNTSATSNQDILTNTEIPLQLVTVSGNETME |
response to pH transepithelial chloride transport | chloride channel complex; intracellular membrane-bounded organelle; lysosomal membrane | antiporter activity ATP binding chloride transmembrane transporter activity voltage-gated chloride channel activity | Mus musculus | Antiport ATP-binding CBS domain Chloride Ion transport Lysosome Membrane Nucleotide-binding Phosphoprotein Reference proteome Repeat Transmembrane Transmembrane helix Transport | MANVSKKVSW | MANVSKKVSWSGRDRDDEEGAPLLRRTGQPDEETPLLNGAGPGARQSHSALFRIGQMNNVELDDELLDPEVDPPHTFPKEIPHNEKLLSLKYESLDYDNSENQLFLEEERRINHTAFRTVEIKRWVICALIGILTGLVACFIDIVVENLAGLKYRVIKDNIDKFTEKGGLSFSLLLWATLNSAFVLVGSVIVAFIEPVAAGSGIPQIKCFLNGVKIPHVVRLKTLVIKVSGVILSVVGGLAVGKEGPMIHSGSVIAAGISQGRSTSLKRDFKIFEYFRRDTEKRDFVSAGAAAGVSAAFGAPVGGVLFSLEEGASFWNQFLTWRIFFASMISTFTLNFVLSIYHGNMWDLSSPGLINFGRFDSEKMAYTIHEIPVFIAMGVVGGILGAVFNALNYWLTMFRIRYIHRPCLQVIEAMLVAAVTATVAFVLIYSSRDCQPLQGSSMSYPLQLFCADGEYNSMAAAFFNTPEKSVVSLFHDPPGSYNPMTLGLFTLVYFFLACWTYGLTVSAGVFIPSLLIGAAWGRLFGISLSYLTGAAIWADPGKYALMGAAAQLGGIVRMTLSLTVIMMEATSNVTYGFPIMLVLMTAKIVGDVFIEGLYDMHIQLQSVPFLHWEAPVTSHSLTAREVMSTPVTCLRRREKVGIIVDVLSDTASNHNGFPVVEDVGDTQPARLQGLILRSQLIVLLKHKVFVERSNMGLVQRRLRLKDFRDAYPRFPPIQSIHVSQDERECTMDLSEFMNPSPYTVPQEASLPRVFKLFRALGLRHLVVVDNHNQVVGLVTRKDLARYRLGKGGLEELSLAQT | response to pH transepithelial chloride transport chloride channel complex; intracellular membrane-bounded organelle; lysosomal membrane antiporter activity ATP binding chloride transmembrane transporter activity voltage-gated chloride channel activity Mus musculus Antiport ATP-binding CBS domain Chloride Ion transport Lysosome Membrane Nucleotide-binding Phosphoprotein Reference proteome Repeat Transmembrane Transmembrane helix Transport MANVSKKVSW MANVSKKVSWSGRDRDDEEGAPLLRRTGQPDEETPLLNGAGPGARQSHSALFRIGQMNNVELDDELLDPEVDPPHTFPKEIPHNEKLLSLKYESLDYDNSENQLFLEEERRINHTAFRTVEIKRWVICALIGILTGLVACFIDIVVENLAGLKYRVIKDNIDKFTEKGGLSFSLLLWATLNSAFVLVGSVIVAFIEPVAAGSGIPQIKCFLNGVKIPHVVRLKTLVIKVSGVILSVVGGLAVGKEGPMIHSGSVIAAGISQGRSTSLKRDFKIFEYFRRDTEKRDFVSAGAAAGVSAAFGAPVGGVLFSLEEGASFWNQFLTWRIFFASMISTFTLNFVLSIYHGNMWDLSSPGLINFGRFDSEKMAYTIHEIPVFIAMGVVGGILGAVFNALNYWLTMFRIRYIHRPCLQVIEAMLVAAVTATVAFVLIYSSRDCQPLQGSSMSYPLQLFCADGEYNSMAAAFFNTPEKSVVSLFHDPPGSYNPMTLGLFTLVYFFLACWTYGLTVSAGVFIPSLLIGAAWGRLFGISLSYLTGAAIWADPGKYALMGAAAQLGGIVRMTLSLTVIMMEATSNVTYGFPIMLVLMTAKIVGDVFIEGLYDMHIQLQSVPFLHWEAPVTSHSLTAREVMSTPVTCLRRREKVGIIVDVLSDTASNHNGFPVVEDVGDTQPARLQGLILRSQLIVLLKHKVFVERSNMGLVQRRLRLKDFRDAYPRFPPIQSIHVSQDERECTMDLSEFMNPSPYTVPQEASLPRVFKLFRALGLRHLVVVDNHNQVVGLVTRKDLARYRLGKGGLEELSLAQT |
cell surface pattern recognition receptor signaling pathway complement activation, lectin pathway G protein-coupled receptor signaling pathway negative regulation of viral entry into host cell positive regulation of interleukin-8 production positive regulation of opsonization protein localization to cell surface proteolysis recognition of apoptotic cell | collagen trimer; collagen-containing extracellular matrix; extracellular space; plasma membrane; serine-type endopeptidase complex | antigen binding calcium-dependent protein binding carbohydrate derivative binding G protein-coupled receptor binding identical protein binding mannan binding metal ion binding pattern recognition receptor activity proteoglycan binding sialic acid binding signaling receptor binding | Mus musculus | Calcium Collagen Complement activation lectin pathway Disulfide bond Glycoprotein Immunity Innate immunity Lectin Metal-binding Reference proteome Repeat Secreted Signal | MALGSAALFV | MALGSAALFVLTLTVHAAGTCPELKVLDLEGYKQLTILQGCPGLPGAAGPKGEAGAKGDRGESGLPGIPGKEGPTGPKGNQGEKGIRGEKGDSGPSQSCATGPRTCKELLTQGHFLTGWYTIYLPDCRPLTVLCDMDTDGGGWTVFQRRLDGSVDFFRDWTSYKRGFGSQLGEFWLGNDNIHALTTQGTSELRVDLSDFEGKHDFAKYSSFQIQGEAEKYKLILGNFLGGGAGDSLTPHNNRLFSTKDQDNDGSTSSCAMGYHGAWWYSQCHTSNLNGLYLRGPHKSYANGVNWKSWRGYNYSCKVSEMKVRLI | cell surface pattern recognition receptor signaling pathway complement activation, lectin pathway G protein-coupled receptor signaling pathway negative regulation of viral entry into host cell positive regulation of interleukin-8 production positive regulation of opsonization protein localization to cell surface proteolysis recognition of apoptotic cell collagen trimer; collagen-containing extracellular matrix; extracellular space; plasma membrane; serine-type endopeptidase complex antigen binding calcium-dependent protein binding carbohydrate derivative binding G protein-coupled receptor binding identical protein binding mannan binding metal ion binding pattern recognition receptor activity proteoglycan binding sialic acid binding signaling receptor binding Mus musculus Calcium Collagen Complement activation lectin pathway Disulfide bond Glycoprotein Immunity Innate immunity Lectin Metal-binding Reference proteome Repeat Secreted Signal MALGSAALFV MALGSAALFVLTLTVHAAGTCPELKVLDLEGYKQLTILQGCPGLPGAAGPKGEAGAKGDRGESGLPGIPGKEGPTGPKGNQGEKGIRGEKGDSGPSQSCATGPRTCKELLTQGHFLTGWYTIYLPDCRPLTVLCDMDTDGGGWTVFQRRLDGSVDFFRDWTSYKRGFGSQLGEFWLGNDNIHALTTQGTSELRVDLSDFEGKHDFAKYSSFQIQGEAEKYKLILGNFLGGGAGDSLTPHNNRLFSTKDQDNDGSTSSCAMGYHGAWWYSQCHTSNLNGLYLRGPHKSYANGVNWKSWRGYNYSCKVSEMKVRLI |
estrogen biosynthetic process extracellular matrix organization fatty acid elongation, saturated fatty acid positive regulation of cell-substrate adhesion | endoplasmic reticulum; extracellular matrix; fatty acid elongase complex | collagen binding estradiol 17-beta-dehydrogenase activity fibronectin binding heparin binding long-chain-3-hydroxyacyl-CoA dehydrogenase activity oxidoreductase activity very-long-chain 3-oxoacyl-CoA reductase activity | Mus musculus | Alternative splicing Endoplasmic reticulum Lipid biosynthesis Lipid metabolism Membrane NADP Oxidoreductase Reference proteome Steroid biosynthesis Transmembrane Transmembrane helix | MECAPPAAGF | MECAPPAAGFLYWVGASTIAYLALRASYSLFRAFQVWCVGNEALVGPRLGEWAVVTGGTDGIGKAYAEELAKRGMKIVLISRSQDKLNQVSNNIKEKFNVETRTIAVDFSLDDIYDKIKTGLSGLEIGVLVNNVGMSYEYPEYFLEIPDLDNTIKKLININVLSVCKVTRLVLPGMVERSKGVILNISSASGMLPVPLLTIYSATKAFVDFFSQCLHEEYKSKGIFVQSVMPYLVATKLAKIQKPTLDKPSAETFVKSAIKTVGLQTRTTGYVIHSLMGSINSIMPRWMYFKIIMGFSKSLRNRYLKKRKKN | estrogen biosynthetic process extracellular matrix organization fatty acid elongation, saturated fatty acid positive regulation of cell-substrate adhesion endoplasmic reticulum; extracellular matrix; fatty acid elongase complex collagen binding estradiol 17-beta-dehydrogenase activity fibronectin binding heparin binding long-chain-3-hydroxyacyl-CoA dehydrogenase activity oxidoreductase activity very-long-chain 3-oxoacyl-CoA reductase activity Mus musculus Alternative splicing Endoplasmic reticulum Lipid biosynthesis Lipid metabolism Membrane NADP Oxidoreductase Reference proteome Steroid biosynthesis Transmembrane Transmembrane helix MECAPPAAGF MECAPPAAGFLYWVGASTIAYLALRASYSLFRAFQVWCVGNEALVGPRLGEWAVVTGGTDGIGKAYAEELAKRGMKIVLISRSQDKLNQVSNNIKEKFNVETRTIAVDFSLDDIYDKIKTGLSGLEIGVLVNNVGMSYEYPEYFLEIPDLDNTIKKLININVLSVCKVTRLVLPGMVERSKGVILNISSASGMLPVPLLTIYSATKAFVDFFSQCLHEEYKSKGIFVQSVMPYLVATKLAKIQKPTLDKPSAETFVKSAIKTVGLQTRTTGYVIHSLMGSINSIMPRWMYFKIIMGFSKSLRNRYLKKRKKN |
cell-cell signaling fibroblast growth factor receptor signaling pathway myoblast proliferation positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis positive regulation of cell migration involved in sprouting angiogenesis positive regulation of fibroblast growth factor receptor signaling pathway positive regulation of myoblast proliferation | cell surface; extracellular region; plasma membrane | fibroblast growth factor binding growth factor binding | Mus musculus | Cell membrane Disulfide bond Glycoprotein Growth factor binding Membrane Reference proteome Secreted Signal | MRLHSLILLS | MRLHSLILLSFLLLATQAFSEKVRKRAKNAPHSTAEEGVEGSAPSLGKAQNKQRSRTSKSLTHGKFVTKDQATCRWAVTEEEQGISLKVQCTQADQEFSCVFAGDPTDCLKHDKDQIYWKQVARTLRKQKNICRNAKSVLKTRVCRKRFPESNLKLVNPNARGNTKPRKEKAEVSAREHNKVQEAVSTEPNRVKEDITLNPAATQTMAIRDPECLEDPDVLNQRKTALEFCGESWSSICTFFLNMLQATSC | cell-cell signaling fibroblast growth factor receptor signaling pathway myoblast proliferation positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis positive regulation of cell migration involved in sprouting angiogenesis positive regulation of fibroblast growth factor receptor signaling pathway positive regulation of myoblast proliferation cell surface; extracellular region; plasma membrane fibroblast growth factor binding growth factor binding Mus musculus Cell membrane Disulfide bond Glycoprotein Growth factor binding Membrane Reference proteome Secreted Signal MRLHSLILLS MRLHSLILLSFLLLATQAFSEKVRKRAKNAPHSTAEEGVEGSAPSLGKAQNKQRSRTSKSLTHGKFVTKDQATCRWAVTEEEQGISLKVQCTQADQEFSCVFAGDPTDCLKHDKDQIYWKQVARTLRKQKNICRNAKSVLKTRVCRKRFPESNLKLVNPNARGNTKPRKEKAEVSAREHNKVQEAVSTEPNRVKEDITLNPAATQTMAIRDPECLEDPDVLNQRKTALEFCGESWSSICTFFLNMLQATSC |
negative regulation of signal transduction regulation of G protein-coupled receptor signaling pathway response to ethanol | brush border; clathrin-coated vesicle; Golgi membrane | G-protein alpha-subunit binding GTPase activator activity | Rattus norvegicus | Lipoprotein Membrane Palmitate Phosphoprotein Reference proteome Signal transduction inhibitor | MPTPHEAEKQ | MPTPHEAEKQHTGPEEADRPPSMSSHDAAPSGPPSRNPCCLCWCCCCSCSWNQERQRAWQVSRESKLQPLPSCEVCTPPSPEEVQSWAQSFDKLMHSPTGRSVFRAFLRTEYSEENMLFWLACEELKTEADRHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINRKMQEPSPHTFDDAQLQIYTLMHRDSYPRFLTSPTYRSLLLQGAPQSSEA | negative regulation of signal transduction regulation of G protein-coupled receptor signaling pathway response to ethanol brush border; clathrin-coated vesicle; Golgi membrane G-protein alpha-subunit binding GTPase activator activity Rattus norvegicus Lipoprotein Membrane Palmitate Phosphoprotein Reference proteome Signal transduction inhibitor MPTPHEAEKQ MPTPHEAEKQHTGPEEADRPPSMSSHDAAPSGPPSRNPCCLCWCCCCSCSWNQERQRAWQVSRESKLQPLPSCEVCTPPSPEEVQSWAQSFDKLMHSPTGRSVFRAFLRTEYSEENMLFWLACEELKTEADRHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINRKMQEPSPHTFDDAQLQIYTLMHRDSYPRFLTSPTYRSLLLQGAPQSSEA |
dentate gyrus development mRNA destabilization muscle organ development negative regulation of inflammatory response negative regulation of long-term synaptic potentiation negative regulation of translation negative regulation of tumor necrosis factor production non-membrane-bounded organelle assembly nuclear pore complex assembly nuclear pore localization positive regulation of miRNA-mediated gene silencing positive regulation of translation post-transcriptional regulation of gene expression regulation of circadian sleep/wake cycle, sleep regulation of neurogenesis regulation of synaptic transmission, glutamatergic spermatid development | axon; cytoplasmic ribonucleoprotein granule; cytoplasmic stress granule; dendritic spine; intracellular non-membrane-bounded organelle; nuclear envelope | molecular condensate scaffold activity mRNA 3'-UTR AU-rich region binding mRNA binding protein heterodimerization activity protein homodimerization activity RNA strand annealing activity | Cricetulus griseus | Acetylation Cell projection Cytoplasm Developmental protein Differentiation Isopeptide bond Methylation Myogenesis Nucleus Phosphoprotein Repeat RNA-binding Spermatogenesis Synapse Ubl conjugation | MADVTVEVRG | MADVTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEISEGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKRVNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIYGESAEAVKKARGFMEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRETRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHGPSEKAINGPTSASGDEIPNVPRTPGEEKTKNLKEESTQEAAVLNGVS | dentate gyrus development mRNA destabilization muscle organ development negative regulation of inflammatory response negative regulation of long-term synaptic potentiation negative regulation of translation negative regulation of tumor necrosis factor production non-membrane-bounded organelle assembly nuclear pore complex assembly nuclear pore localization positive regulation of miRNA-mediated gene silencing positive regulation of translation post-transcriptional regulation of gene expression regulation of circadian sleep/wake cycle, sleep regulation of neurogenesis regulation of synaptic transmission, glutamatergic spermatid development axon; cytoplasmic ribonucleoprotein granule; cytoplasmic stress granule; dendritic spine; intracellular non-membrane-bounded organelle; nuclear envelope molecular condensate scaffold activity mRNA 3'-UTR AU-rich region binding mRNA binding protein heterodimerization activity protein homodimerization activity RNA strand annealing activity Cricetulus griseus Acetylation Cell projection Cytoplasm Developmental protein Differentiation Isopeptide bond Methylation Myogenesis Nucleus Phosphoprotein Repeat RNA-binding Spermatogenesis Synapse Ubl conjugation MADVTVEVRG MADVTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEISEGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKRVNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIYGESAEAVKKARGFMEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRETRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHGPSEKAINGPTSASGDEIPNVPRTPGEEKTKNLKEESTQEAAVLNGVS |
pexophagy protein import into peroxisome matrix protein import into peroxisome matrix, receptor recycling protein import into peroxisome matrix, substrate release protein import into peroxisome matrix, translocation protein targeting to peroxisome protein tetramerization | cytosol; peroxisomal matrix; peroxisome | peroxisome matrix targeting signal-1 binding protein carrier chaperone | Cavia porcellus | Alternative splicing Cytoplasm Isopeptide bond Peroxisome Phosphoprotein Protein transport Reference proteome Repeat Thioester bond TPR repeat Translocation Transport Ubl conjugation | MAMRELVEGE | MAMRELVEGECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASETVSKPLGVASEDELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQEIEQSNFRQAPQRAPGVADLALSENWAQEFLAAGDAVDVTQDYNETDWSQEFIAEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGAATTDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEFLKFVRQIGEGQVSLESVAGSGRAQAEQWAAEFIQQQGTSDAWVDQFTRPVNTSALDMEFERAKSAIESDVDFWDKLQAELEEMAKRDAEAHPWLSDYDDLTSASYDKGYQFEEENPLRDHPQPFEEGLLRLEEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNRTALMALAVSFTNESLQRQACETLRDWLRCTPAYAHLVTPAEEGAGGAGLGSSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMSENIWSTLRLALSMLGQSDAYRAADARDLSALLALFGLSQ | pexophagy protein import into peroxisome matrix protein import into peroxisome matrix, receptor recycling protein import into peroxisome matrix, substrate release protein import into peroxisome matrix, translocation protein targeting to peroxisome protein tetramerization cytosol; peroxisomal matrix; peroxisome peroxisome matrix targeting signal-1 binding protein carrier chaperone Cavia porcellus Alternative splicing Cytoplasm Isopeptide bond Peroxisome Phosphoprotein Protein transport Reference proteome Repeat Thioester bond TPR repeat Translocation Transport Ubl conjugation MAMRELVEGE MAMRELVEGECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASETVSKPLGVASEDELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQEIEQSNFRQAPQRAPGVADLALSENWAQEFLAAGDAVDVTQDYNETDWSQEFIAEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGAATTDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEFLKFVRQIGEGQVSLESVAGSGRAQAEQWAAEFIQQQGTSDAWVDQFTRPVNTSALDMEFERAKSAIESDVDFWDKLQAELEEMAKRDAEAHPWLSDYDDLTSASYDKGYQFEEENPLRDHPQPFEEGLLRLEEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNRTALMALAVSFTNESLQRQACETLRDWLRCTPAYAHLVTPAEEGAGGAGLGSSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMSENIWSTLRLALSMLGQSDAYRAADARDLSALLALFGLSQ |
chondrocyte differentiation chondrocyte proliferation ossification sulfate transmembrane transport sulfate transport | apical plasma membrane; microvillus membrane; plasma membrane | bicarbonate transmembrane transporter activity chloride transmembrane transporter activity oxalate transmembrane transporter activity secondary active sulfate transmembrane transporter activity solute:inorganic anion antiporter activity sulfate transmembrane transporter activity | Rattus norvegicus | Cell membrane Glycoprotein Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport | MSSENKEQHN | MSSENKEQHNLSPRDLPEEAYGFPPELPLGAQRGSSTDLRQFEPSDRRRAFRRIHMELHEKPDTNIRQLVMRKLQKSCQCNATKIRNRIFDFFPVLRWLPKYDLKKNILGDMMSGLIVGILLVPQSIAYSLLAGQEPIYGLYTSFFASIIYFLFGTSRHISVGIFGILCLMIGEVVDRELHKACPDIDTTSSSIAMFSNGCVVVNHTLDGLCDKSCYAIKIGSTVTFMAGVYQVAMGFFQVGFVSVYLSDALLSGFVTGASFTILTSQAKYLLGLSLPRSNGVGSVITTWIHIFRNIHKTNICDLITSLLCLLVLVPTKELNEYFKSKLPAPIPTELIVVVAATLASHFGKLNENYNSSIAGQIPTGFMPPQAPDWSLIPNVAVDAIAISIIGFAITVSLSEMFAKKHGYTVKANQEMYAIGFCNIIPSFFHCITTSAALAKTLVKESTGCQTQLSAIVTSLVLLLVLLLIAPLFYSLQKCVLGVITIVNLRGALLKFRDLPKMWRLSRMDTVIWFVTMLSSALLSTEIGLLVGVCFSMFCVILRTQMPKISLLGLEEESEIFESISTYKNLRSKSGIKVFRFIAPLYYINKECFKSALYKKTLNPVLVKAAWKKAAKRKLKEETVTFHGDPDEVSMQLSHDPLELHTVVIDCSAIQFLDTAGIHTLKEVRRDYEAIGIQVLLAQCNPSVRDSLAKGEYCKKEEENLLFYSLSEAVAFAEESQKEKGVCVVNGLSLSGD | chondrocyte differentiation chondrocyte proliferation ossification sulfate transmembrane transport sulfate transport apical plasma membrane; microvillus membrane; plasma membrane bicarbonate transmembrane transporter activity chloride transmembrane transporter activity oxalate transmembrane transporter activity secondary active sulfate transmembrane transporter activity solute:inorganic anion antiporter activity sulfate transmembrane transporter activity Rattus norvegicus Cell membrane Glycoprotein Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport MSSENKEQHN MSSENKEQHNLSPRDLPEEAYGFPPELPLGAQRGSSTDLRQFEPSDRRRAFRRIHMELHEKPDTNIRQLVMRKLQKSCQCNATKIRNRIFDFFPVLRWLPKYDLKKNILGDMMSGLIVGILLVPQSIAYSLLAGQEPIYGLYTSFFASIIYFLFGTSRHISVGIFGILCLMIGEVVDRELHKACPDIDTTSSSIAMFSNGCVVVNHTLDGLCDKSCYAIKIGSTVTFMAGVYQVAMGFFQVGFVSVYLSDALLSGFVTGASFTILTSQAKYLLGLSLPRSNGVGSVITTWIHIFRNIHKTNICDLITSLLCLLVLVPTKELNEYFKSKLPAPIPTELIVVVAATLASHFGKLNENYNSSIAGQIPTGFMPPQAPDWSLIPNVAVDAIAISIIGFAITVSLSEMFAKKHGYTVKANQEMYAIGFCNIIPSFFHCITTSAALAKTLVKESTGCQTQLSAIVTSLVLLLVLLLIAPLFYSLQKCVLGVITIVNLRGALLKFRDLPKMWRLSRMDTVIWFVTMLSSALLSTEIGLLVGVCFSMFCVILRTQMPKISLLGLEEESEIFESISTYKNLRSKSGIKVFRFIAPLYYINKECFKSALYKKTLNPVLVKAAWKKAAKRKLKEETVTFHGDPDEVSMQLSHDPLELHTVVIDCSAIQFLDTAGIHTLKEVRRDYEAIGIQVLLAQCNPSVRDSLAKGEYCKKEEENLLFYSLSEAVAFAEESQKEKGVCVVNGLSLSGD |
bone mineralization cell differentiation embryonic skeletal system development multicellular organism growth negative regulation of fat cell differentiation negative regulation of Notch signaling pathway negative regulation of vascular endothelial cell proliferation ossification osteoblast differentiation positive regulation of bone resorption positive regulation of cytokine production post-embryonic development regulation of gene expression | cytoplasm; external side of plasma membrane; extracellular space; membrane | calcium ion binding | Rattus norvegicus | Cytoplasm Disulfide bond EGF-like domain Glycoprotein Membrane Reference proteome Repeat Signal Transmembrane Transmembrane helix | MIATGALLRV | MIATGALLRVLLLLLAFGHSTYGAECDPACDPQHGFCEADNVCRCEPGWEGPLCEKCVTSPGCVNGLCEEPWQCVCKEGWDGKFCEIDIRACTSTPCANNGTCVDLEKGQYECSCTPGFSGKDCQHKAGPCVINGSPCQHGGACVDDEGRASHASCLCPPGFSGNFCEIVTNSCTPNPCENDGVCTDIGGDFRCRCPAGFVDKTCSRPVSNCASGPCLNGGTCLQHTQVSFECLCKPPFMGPTCAKKRGTSPVQVTHLPSGYGLTYRLTPGVHELPVQQPEHHILKVSMKELNKSAPLLTEGQAICFTILGVLTSLVVLGTVAIVFLNKCEAWVSNLRYNHMLRKKKNLLLQYNSGEELAVNIIFPEKIDMTTFNKEAGDEDI | bone mineralization cell differentiation embryonic skeletal system development multicellular organism growth negative regulation of fat cell differentiation negative regulation of Notch signaling pathway negative regulation of vascular endothelial cell proliferation ossification osteoblast differentiation positive regulation of bone resorption positive regulation of cytokine production post-embryonic development regulation of gene expression cytoplasm; external side of plasma membrane; extracellular space; membrane calcium ion binding Rattus norvegicus Cytoplasm Disulfide bond EGF-like domain Glycoprotein Membrane Reference proteome Repeat Signal Transmembrane Transmembrane helix MIATGALLRV MIATGALLRVLLLLLAFGHSTYGAECDPACDPQHGFCEADNVCRCEPGWEGPLCEKCVTSPGCVNGLCEEPWQCVCKEGWDGKFCEIDIRACTSTPCANNGTCVDLEKGQYECSCTPGFSGKDCQHKAGPCVINGSPCQHGGACVDDEGRASHASCLCPPGFSGNFCEIVTNSCTPNPCENDGVCTDIGGDFRCRCPAGFVDKTCSRPVSNCASGPCLNGGTCLQHTQVSFECLCKPPFMGPTCAKKRGTSPVQVTHLPSGYGLTYRLTPGVHELPVQQPEHHILKVSMKELNKSAPLLTEGQAICFTILGVLTSLVVLGTVAIVFLNKCEAWVSNLRYNHMLRKKKNLLLQYNSGEELAVNIIFPEKIDMTTFNKEAGDEDI |
cholesterol efflux cholesterol homeostasis cholesterol metabolic process cholesterol storage macrophage derived foam cell differentiation positive regulation of amyloid precursor protein biosynthetic process very-low-density lipoprotein particle assembly | endoplasmic reticulum; endoplasmic reticulum membrane; membrane | cholesterol binding cholesterol O-acyltransferase activity fatty-acyl-CoA binding sterol O-acyltransferase activity | Rattus norvegicus | Acetylation Acyltransferase Cholesterol metabolism Disulfide bond Endoplasmic reticulum Lipid metabolism Membrane Phosphoprotein Reference proteome Steroid metabolism Sterol metabolism Transferase Transmembrane Transmembrane helix | MVGEETSLRN | MVGEETSLRNRLSRSAENPEQDEAQKNLLDTHRNGHITMKQLIAKKRQLAAEAEELKPLFLKEVGCHFDDFVTNLIDKSASLDNGGCALTTFSILEEMKNNHRAKDLRAPPEQGKIFISRRSLLDELFEVDHIRTIYHMFIALLIIFILSTLVVDYIDEGRLVLEFSLLAYAFGQFPIVIWTWWAMFLSTLAIPYFLFQRWAHGYSKSSHPLIYSLIHGAFFLVFQLGILGFIPTYVVLAYTLPPASRFILILEQIRLVMKAHSYVRENVPRVLSAAKEKSSTVPVPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFLQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCVFNSILPGVLMLFLSFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYVYKDLLWFFSKRFRPAAMLAVFALSAVVHEYALAVCLSYFYPVLFVLFMFFGMAFNFIVNDSRKRPVWNIMVRASLFLGHGVILCFYSQEWYARQRCPLKNPTFLDYVRPRTWTCRYVF | cholesterol efflux cholesterol homeostasis cholesterol metabolic process cholesterol storage macrophage derived foam cell differentiation positive regulation of amyloid precursor protein biosynthetic process very-low-density lipoprotein particle assembly endoplasmic reticulum; endoplasmic reticulum membrane; membrane cholesterol binding cholesterol O-acyltransferase activity fatty-acyl-CoA binding sterol O-acyltransferase activity Rattus norvegicus Acetylation Acyltransferase Cholesterol metabolism Disulfide bond Endoplasmic reticulum Lipid metabolism Membrane Phosphoprotein Reference proteome Steroid metabolism Sterol metabolism Transferase Transmembrane Transmembrane helix MVGEETSLRN MVGEETSLRNRLSRSAENPEQDEAQKNLLDTHRNGHITMKQLIAKKRQLAAEAEELKPLFLKEVGCHFDDFVTNLIDKSASLDNGGCALTTFSILEEMKNNHRAKDLRAPPEQGKIFISRRSLLDELFEVDHIRTIYHMFIALLIIFILSTLVVDYIDEGRLVLEFSLLAYAFGQFPIVIWTWWAMFLSTLAIPYFLFQRWAHGYSKSSHPLIYSLIHGAFFLVFQLGILGFIPTYVVLAYTLPPASRFILILEQIRLVMKAHSYVRENVPRVLSAAKEKSSTVPVPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFLQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCVFNSILPGVLMLFLSFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYVYKDLLWFFSKRFRPAAMLAVFALSAVVHEYALAVCLSYFYPVLFVLFMFFGMAFNFIVNDSRKRPVWNIMVRASLFLGHGVILCFYSQEWYARQRCPLKNPTFLDYVRPRTWTCRYVF |
adult heart development cardiac muscle cell development cardiac muscle contraction cardiac muscle hypertrophy cardiac muscle hypertrophy in response to stress cardiac muscle tissue morphogenesis cardiac myofibril assembly detection of muscle stretch otic vesicle formation sarcomere organization sarcomerogenesis skeletal muscle contraction skeletal muscle myosin thick filament assembly skeletal muscle thin filament assembly somitogenesis | I band; Z disc | BMP binding FATZ binding molecular adaptor activity protein-macromolecule adaptor activity structural constituent of muscle titin binding titin Z domain binding transmembrane transporter binding | Mus musculus | Cytoplasm Phosphoprotein Reference proteome | MATSELSCQV | MATSELSCQVSEENQERREAFWAEWKDLTLSTRPEEGCSLHEEDTQRHETYHRQGQCQAVVQRSPWLVMRLGILGRGLQEYQLPYQRVLPLPIFTPTKVGASKEEREETPIQLRELLALETALGGQCVERQDVAEITKQLPPVVPVSKPGPLRRTLSRSMSQEAQRG | adult heart development cardiac muscle cell development cardiac muscle contraction cardiac muscle hypertrophy cardiac muscle hypertrophy in response to stress cardiac muscle tissue morphogenesis cardiac myofibril assembly detection of muscle stretch otic vesicle formation sarcomere organization sarcomerogenesis skeletal muscle contraction skeletal muscle myosin thick filament assembly skeletal muscle thin filament assembly somitogenesis I band; Z disc BMP binding FATZ binding molecular adaptor activity protein-macromolecule adaptor activity structural constituent of muscle titin binding titin Z domain binding transmembrane transporter binding Mus musculus Cytoplasm Phosphoprotein Reference proteome MATSELSCQV MATSELSCQVSEENQERREAFWAEWKDLTLSTRPEEGCSLHEEDTQRHETYHRQGQCQAVVQRSPWLVMRLGILGRGLQEYQLPYQRVLPLPIFTPTKVGASKEEREETPIQLRELLALETALGGQCVERQDVAEITKQLPPVVPVSKPGPLRRTLSRSMSQEAQRG |
cell differentiation chromosome segregation intracellular signal transduction negative regulation of viral genome replication positive regulation of viral genome replication protein phosphorylation regulation of mRNA processing spliceosomal complex assembly | chromatin; cytoplasm; cytosol; endoplasmic reticulum; nuclear matrix; nuclear speck; nucleoplasm; nucleus; plasma membrane | ATP binding magnesium ion binding protein serine kinase activity protein serine/threonine kinase activity | Mus musculus | ATP-binding Chromosome Chromosome partition Cytoplasm Differentiation Direct protein sequencing Endoplasmic reticulum Kinase Microsome mRNA processing mRNA splicing Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MERKVLALQA | MERKVLALQARKKRTKAKKDKAQRKPETQHRGSAPHSESDIPEQEEEILGSDDDEQEDPNDYCKGGYHLVKIGDLFNGRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTETALDEIRLLKSVRNSDPNDPNGEMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILLSVNEQYIRRLAAEATEWQRSGAPPPSGSAVSTAPQPKPADKMSKNKKKKLKKKQKRQAELLEKRMQEIEEMEKESGPGQKRPNKQEESESPVDRPLTENPPNKMTQEKLEESNSIGQDQTLTERGGEGGAPEINCNGVIGVVNYPENSNNETLRHKEDLHNANDCDVHTLKQEPSFLNSSNGDSSPSQDTDSCTPTASETMVCQSSAEQSLTRQDITQLEESIRADTPSGDEQEPNGALDSKGKFSAGNFLINPLEPKNAEKLQVKIADLGNACWVHKHFTEDIQTRQYRSLEVLIGSGYNTPADIWSTACMAFELATGDYLFEPHSGEDYTRDEDHIALIIELLGKVPRKLIVAGKYSKEFFTKKGDLKHITKLKPWGLLEVLVEKYEWPQEEAAGFTDFLLPMLELMPEKRATAAECLRHPWLNS | cell differentiation chromosome segregation intracellular signal transduction negative regulation of viral genome replication positive regulation of viral genome replication protein phosphorylation regulation of mRNA processing spliceosomal complex assembly chromatin; cytoplasm; cytosol; endoplasmic reticulum; nuclear matrix; nuclear speck; nucleoplasm; nucleus; plasma membrane ATP binding magnesium ion binding protein serine kinase activity protein serine/threonine kinase activity Mus musculus ATP-binding Chromosome Chromosome partition Cytoplasm Differentiation Direct protein sequencing Endoplasmic reticulum Kinase Microsome mRNA processing mRNA splicing Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase MERKVLALQA MERKVLALQARKKRTKAKKDKAQRKPETQHRGSAPHSESDIPEQEEEILGSDDDEQEDPNDYCKGGYHLVKIGDLFNGRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTETALDEIRLLKSVRNSDPNDPNGEMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILLSVNEQYIRRLAAEATEWQRSGAPPPSGSAVSTAPQPKPADKMSKNKKKKLKKKQKRQAELLEKRMQEIEEMEKESGPGQKRPNKQEESESPVDRPLTENPPNKMTQEKLEESNSIGQDQTLTERGGEGGAPEINCNGVIGVVNYPENSNNETLRHKEDLHNANDCDVHTLKQEPSFLNSSNGDSSPSQDTDSCTPTASETMVCQSSAEQSLTRQDITQLEESIRADTPSGDEQEPNGALDSKGKFSAGNFLINPLEPKNAEKLQVKIADLGNACWVHKHFTEDIQTRQYRSLEVLIGSGYNTPADIWSTACMAFELATGDYLFEPHSGEDYTRDEDHIALIIELLGKVPRKLIVAGKYSKEFFTKKGDLKHITKLKPWGLLEVLVEKYEWPQEEAAGFTDFLLPMLELMPEKRATAAECLRHPWLNS |
maternal-to-zygotic transition of gene expression negative regulation of cell population proliferation negative regulation of mitotic cell cycle | cytoplasm; cytosol; nucleus | mRNA 3'-UTR binding | Mus musculus | Reference proteome | MRDEIATAVF | MRDEIATAVFFVTRLVKKHEKLSTQQIETFALKLMTILFEKYRGHWHPDCPSKGQAFRCIRINNNENKDPVLERACAESNVNFFHLGLPKEMTIWVDPYEVCCRYGEKKHPFTIASFKGRWENWELAQHVSCAVNRATGDCSSGTSSDEESCSREAQIIPKVNNPKSVYQVENFKQSLQPWFCLPRRKHLADGRGFLPGAACHPVPKSSKWCRPASRRVDRYHWVNAQLFSGQTAPGEPGEEALSSLKQK | maternal-to-zygotic transition of gene expression negative regulation of cell population proliferation negative regulation of mitotic cell cycle cytoplasm; cytosol; nucleus mRNA 3'-UTR binding Mus musculus Reference proteome MRDEIATAVF MRDEIATAVFFVTRLVKKHEKLSTQQIETFALKLMTILFEKYRGHWHPDCPSKGQAFRCIRINNNENKDPVLERACAESNVNFFHLGLPKEMTIWVDPYEVCCRYGEKKHPFTIASFKGRWENWELAQHVSCAVNRATGDCSSGTSSDEESCSREAQIIPKVNNPKSVYQVENFKQSLQPWFCLPRRKHLADGRGFLPGAACHPVPKSSKWCRPASRRVDRYHWVNAQLFSGQTAPGEPGEEALSSLKQK |
cellular response to fatty acid cellular response to starvation glucose homeostasis insulin receptor signaling pathway negative regulation of anoikis phosphorylation reactive oxygen species metabolic process regulation of acetyl-CoA biosynthetic process from pyruvate regulation of bone resorption regulation of cellular ketone metabolic process regulation of fatty acid biosynthetic process regulation of fatty acid oxidation regulation of glucose metabolic process regulation of pH response to starvation | mitochondrial inner membrane; mitochondrial matrix; mitochondrion | ATP binding protein kinase activity protein serine/threonine/tyrosine kinase activity pyruvate dehydrogenase (acetyl-transferring) kinase activity | Mus musculus | ATP-binding Kinase Mitochondrion Nucleotide-binding Reference proteome Transferase Transit peptide | MKAARFVMRS | MKAARFVMRSASSLSSASLVPREVELFSRYSPSPLSMKQLLDFGSENACERTSFAFLRQELPVRLANILKEIDILPDRLVNTPSVQLVKSWYIQSLMDLVEFHEKSPEDQKALSEFVDTLVKVRNRHHNVVPTMAQGILEYKDTCTVDPVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSKTGNPSHIGSIDPNCDVVAVVQDAFECAKMLCDQYYLTSPELNLTQVNGKFPGQPIHIVYVPSHLHHMLFELFKNAMRATVEHQENRPSLTPVEATVVLGKEDLTIKISDRGGGVPLRITDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSMSGYGTDAIIYLKALSSESVEKLPVFNKSAFKHYQMSSEADDWCIPSREPKNLAKEKLAV | cellular response to fatty acid cellular response to starvation glucose homeostasis insulin receptor signaling pathway negative regulation of anoikis phosphorylation reactive oxygen species metabolic process regulation of acetyl-CoA biosynthetic process from pyruvate regulation of bone resorption regulation of cellular ketone metabolic process regulation of fatty acid biosynthetic process regulation of fatty acid oxidation regulation of glucose metabolic process regulation of pH response to starvation mitochondrial inner membrane; mitochondrial matrix; mitochondrion ATP binding protein kinase activity protein serine/threonine/tyrosine kinase activity pyruvate dehydrogenase (acetyl-transferring) kinase activity Mus musculus ATP-binding Kinase Mitochondrion Nucleotide-binding Reference proteome Transferase Transit peptide MKAARFVMRS MKAARFVMRSASSLSSASLVPREVELFSRYSPSPLSMKQLLDFGSENACERTSFAFLRQELPVRLANILKEIDILPDRLVNTPSVQLVKSWYIQSLMDLVEFHEKSPEDQKALSEFVDTLVKVRNRHHNVVPTMAQGILEYKDTCTVDPVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSKTGNPSHIGSIDPNCDVVAVVQDAFECAKMLCDQYYLTSPELNLTQVNGKFPGQPIHIVYVPSHLHHMLFELFKNAMRATVEHQENRPSLTPVEATVVLGKEDLTIKISDRGGGVPLRITDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSMSGYGTDAIIYLKALSSESVEKLPVFNKSAFKHYQMSSEADDWCIPSREPKNLAKEKLAV |
ceramide biosynthetic process ceramide metabolic process intracellular signal transduction positive regulation of apoptotic process response to mechanical stimulus sphingolipid catabolic process sphingomyelin catabolic process sphingomyelin metabolic process | caveola; cell periphery; endoplasmic reticulum; plasma membrane | metal ion binding phosphoric diester hydrolase activity sphingomyelin phosphodiesterase activity | Mus musculus | Cell membrane Hydrolase Lipid metabolism Magnesium Membrane Metal-binding Reference proteome Sphingolipid metabolism Transmembrane Transmembrane helix | MKLNFSLRLR | MKLNFSLRLRVFNLNCWDIPYLSKHRADRMKRLGDFLNLENFDLALLEEVWSEQDFQYLRQRLSLTYPDAHYFRSGMIGSGLCVFSKHPIQEIFQHVYSLNGYPYMFHHGDWFCGKSVGLLVLRLSGLVLNAYVTHLHAEYSRQKDIYFAHRVAQAWELAQFIHHTSKNADVVLLCGDLNMHPKDLGCCLLKEWTGLHDAFVETEDFKGSDDGCTMVPKNCYVSQQDLGPFPSGIRIDYVLYKAVSEFHVCCETLKTTTGCDPHSDKPFSDHEALMATLYVKHSPPQEDPCTACGPLERSDLISVLREARTELGLGIAKARWWAAFSGYVIVWGLSLLVLLCVLAAGEEAREVAIILCIPSVGLVLVAGAVYLFHKQEAKGLCRAQAEMLHVLTRETETQDRGSEPHLAYCLQQEGDRA | ceramide biosynthetic process ceramide metabolic process intracellular signal transduction positive regulation of apoptotic process response to mechanical stimulus sphingolipid catabolic process sphingomyelin catabolic process sphingomyelin metabolic process caveola; cell periphery; endoplasmic reticulum; plasma membrane metal ion binding phosphoric diester hydrolase activity sphingomyelin phosphodiesterase activity Mus musculus Cell membrane Hydrolase Lipid metabolism Magnesium Membrane Metal-binding Reference proteome Sphingolipid metabolism Transmembrane Transmembrane helix MKLNFSLRLR MKLNFSLRLRVFNLNCWDIPYLSKHRADRMKRLGDFLNLENFDLALLEEVWSEQDFQYLRQRLSLTYPDAHYFRSGMIGSGLCVFSKHPIQEIFQHVYSLNGYPYMFHHGDWFCGKSVGLLVLRLSGLVLNAYVTHLHAEYSRQKDIYFAHRVAQAWELAQFIHHTSKNADVVLLCGDLNMHPKDLGCCLLKEWTGLHDAFVETEDFKGSDDGCTMVPKNCYVSQQDLGPFPSGIRIDYVLYKAVSEFHVCCETLKTTTGCDPHSDKPFSDHEALMATLYVKHSPPQEDPCTACGPLERSDLISVLREARTELGLGIAKARWWAAFSGYVIVWGLSLLVLLCVLAAGEEAREVAIILCIPSVGLVLVAGAVYLFHKQEAKGLCRAQAEMLHVLTRETETQDRGSEPHLAYCLQQEGDRA |
acetylcholine transport amine transport amino acid import across plasma membrane choline transport dopamine transport dopamine uptake epinephrine transport export across plasma membrane histamine transport histamine uptake L-alpha-amino acid transmembrane transport L-arginine import across plasma membrane monoatomic cation transport neurotransmitter transport norepinephrine transport norepinephrine uptake organic cation transport positive regulation of gene expression prostaglandin transport putrescine transport quaternary ammonium group transport serotonin transport serotonin uptake thiamine transmembrane transport toxin transport xenobiotic transport xenobiotic transport across blood-brain barrier | apical plasma membrane; basal plasma membrane; basolateral plasma membrane; cholinergic synapse; plasma membrane; presynaptic membrane; synaptic vesicle membrane | acetylcholine transmembrane transporter activity amine transmembrane transporter activity choline transmembrane transporter activity efflux transmembrane transporter activity L-amino acid transmembrane transporter activity L-arginine transmembrane transporter activity monoamine transmembrane transporter activity neurotransmitter transmembrane transporter activity organic anion transmembrane transporter activity organic cation transmembrane transporter activity prostaglandin transmembrane transporter activity putrescine transmembrane transporter activity pyrimidine nucleoside transmembrane transporter activity quaternary ammonium group transmembrane transporter activity steroid binding thiamine transmembrane transporter activity toxin transmembrane transporter activity xenobiotic transmembrane transporter activity | Mus musculus | Alternative splicing Cell membrane Glycoprotein Ion transport Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport | MPTVDDILEH | MPTVDDILEHIGEFHLFQKQTFFLLALLSGAFTPIYVGIVFLGFTPNHHCRSPGVAELSQRCGWSPAEELNYTVPGLGSAGEVSFLSQCMRYEVDWNQSTLDCVDPLSSLAANRSHLPLSPCEHGWVYDTPGSSIVTEFNLVCAHSWMLDLFQSLVNVGFFIGAVGIGYLADRFGRKFCLLVTILINAISGVLMAISPNYAWMLVFRFLQGLVSKAGWLIGYILITEFVGLGYRRTVGICYQIAFTVGLLILAGVAYALPNWRWLQFAVTLPNFCFLLYFWCIPESPRWLISQNKNAKAMKIIKHIAKKNGKSVPVSLQSLTADEDTGMKLNPSFLDLVRTPQIRKHTLILMYNWFTSSVLYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFIIILTIDRIGRRYPWAVSNMVAGAACLASVFIPDDLQWLKITVACLGRMGITIAYEMVCLVNAELYPTYIRNLAVLVCSSMCDIGGIVTPFLVYRLTDIWLEFPLVVFAVVGLVAGGLVLLLPETKGKALPETIEDAEKMQRPRKKKEKRIYLQVKKAELS | acetylcholine transport amine transport amino acid import across plasma membrane choline transport dopamine transport dopamine uptake epinephrine transport export across plasma membrane histamine transport histamine uptake L-alpha-amino acid transmembrane transport L-arginine import across plasma membrane monoatomic cation transport neurotransmitter transport norepinephrine transport norepinephrine uptake organic cation transport positive regulation of gene expression prostaglandin transport putrescine transport quaternary ammonium group transport serotonin transport serotonin uptake thiamine transmembrane transport toxin transport xenobiotic transport xenobiotic transport across blood-brain barrier apical plasma membrane; basal plasma membrane; basolateral plasma membrane; cholinergic synapse; plasma membrane; presynaptic membrane; synaptic vesicle membrane acetylcholine transmembrane transporter activity amine transmembrane transporter activity choline transmembrane transporter activity efflux transmembrane transporter activity L-amino acid transmembrane transporter activity L-arginine transmembrane transporter activity monoamine transmembrane transporter activity neurotransmitter transmembrane transporter activity organic anion transmembrane transporter activity organic cation transmembrane transporter activity prostaglandin transmembrane transporter activity putrescine transmembrane transporter activity pyrimidine nucleoside transmembrane transporter activity quaternary ammonium group transmembrane transporter activity steroid binding thiamine transmembrane transporter activity toxin transmembrane transporter activity xenobiotic transmembrane transporter activity Mus musculus Alternative splicing Cell membrane Glycoprotein Ion transport Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport MPTVDDILEH MPTVDDILEHIGEFHLFQKQTFFLLALLSGAFTPIYVGIVFLGFTPNHHCRSPGVAELSQRCGWSPAEELNYTVPGLGSAGEVSFLSQCMRYEVDWNQSTLDCVDPLSSLAANRSHLPLSPCEHGWVYDTPGSSIVTEFNLVCAHSWMLDLFQSLVNVGFFIGAVGIGYLADRFGRKFCLLVTILINAISGVLMAISPNYAWMLVFRFLQGLVSKAGWLIGYILITEFVGLGYRRTVGICYQIAFTVGLLILAGVAYALPNWRWLQFAVTLPNFCFLLYFWCIPESPRWLISQNKNAKAMKIIKHIAKKNGKSVPVSLQSLTADEDTGMKLNPSFLDLVRTPQIRKHTLILMYNWFTSSVLYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFIIILTIDRIGRRYPWAVSNMVAGAACLASVFIPDDLQWLKITVACLGRMGITIAYEMVCLVNAELYPTYIRNLAVLVCSSMCDIGGIVTPFLVYRLTDIWLEFPLVVFAVVGLVAGGLVLLLPETKGKALPETIEDAEKMQRPRKKKEKRIYLQVKKAELS |
calcium ion transmembrane transport establishment of localization in cell positive regulation of muscle contraction regulation of calcium ion transmembrane transport via high voltage-gated calcium channel sarcoplasmic reticulum calcium ion transport | L-type voltage-gated calcium channel complex; plasma membrane; sarcolemma; T-tubule | calcium channel regulator activity voltage-gated calcium channel activity | Mus musculus | Calcium Calcium channel Calcium transport Cell membrane Disulfide bond Glycoprotein Ion channel Ion transport Membrane Reference proteome Transmembrane Transmembrane helix Transport Voltage-gated channel | MSQTKTAKVR | MSQTKTAKVRVTLFFILVGGVLAMVAVVTDHWAVLSPHLEHHNETCEAAHFGLWRICTARVAVHNKDKSCEHVTPSGEKNCSYFRHFNPGESSEIFEFTTQKEYSISAAAIAIFSLGFIIVGSICAFLSFGNKRDYLLRPASMFYAFAGLCLIVSVEVMRQSVKRMIDSEDTVWIEHYYSWSFACACAAFILLFLGGLFLLLFSLPRMPQNPWESCMDAEPEH | calcium ion transmembrane transport establishment of localization in cell positive regulation of muscle contraction regulation of calcium ion transmembrane transport via high voltage-gated calcium channel sarcoplasmic reticulum calcium ion transport L-type voltage-gated calcium channel complex; plasma membrane; sarcolemma; T-tubule calcium channel regulator activity voltage-gated calcium channel activity Mus musculus Calcium Calcium channel Calcium transport Cell membrane Disulfide bond Glycoprotein Ion channel Ion transport Membrane Reference proteome Transmembrane Transmembrane helix Transport Voltage-gated channel MSQTKTAKVR MSQTKTAKVRVTLFFILVGGVLAMVAVVTDHWAVLSPHLEHHNETCEAAHFGLWRICTARVAVHNKDKSCEHVTPSGEKNCSYFRHFNPGESSEIFEFTTQKEYSISAAAIAIFSLGFIIVGSICAFLSFGNKRDYLLRPASMFYAFAGLCLIVSVEVMRQSVKRMIDSEDTVWIEHYYSWSFACACAAFILLFLGGLFLLLFSLPRMPQNPWESCMDAEPEH |
ADP transport AMP transport ATP transport coenzyme A transmembrane transport FAD transmembrane transport fatty acid beta-oxidation fatty acid transport NAD transport | membrane; mitochondrion; peroxisomal membrane; peroxisome | ADP transmembrane transporter activity AMP transmembrane transporter activity antiporter activity ATP transmembrane transporter activity coenzyme A transmembrane transporter activity FAD transmembrane transporter activity FMN transmembrane transporter activity NAD transmembrane transporter activity protein-folding chaperone binding | Mus musculus | Antiport Cytoplasm Membrane Peroxisome Reference proteome Repeat Transmembrane Transmembrane helix Transport | MASVLSYESL | MASVLSYESLVHAVAGAVGSVTAMTVFFPLDTARLRLQVDEKRKSKTTHAVLLEIIKEEGLLAPYRGWFPVISSLCCSNFVYFYTFNSLKAVWVKGQRSSTGKDLVVGFVAGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIIPTNYKGIIDAFHQIIRDEGILALWNGTFPSLLLVFNPAIQFMFYEGLKRQLLKKRMKLSSLDVFIIGAIAKAIATTVTYPMQTVQSILRFGRHRLNPENRTLGSLRNVLSLLHQRVKRFGIMGLYKGLEAKLLQTVLTAALMFLVYEKLTAATFTVMGLKSTHKH | ADP transport AMP transport ATP transport coenzyme A transmembrane transport FAD transmembrane transport fatty acid beta-oxidation fatty acid transport NAD transport membrane; mitochondrion; peroxisomal membrane; peroxisome ADP transmembrane transporter activity AMP transmembrane transporter activity antiporter activity ATP transmembrane transporter activity coenzyme A transmembrane transporter activity FAD transmembrane transporter activity FMN transmembrane transporter activity NAD transmembrane transporter activity protein-folding chaperone binding Mus musculus Antiport Cytoplasm Membrane Peroxisome Reference proteome Repeat Transmembrane Transmembrane helix Transport MASVLSYESL MASVLSYESLVHAVAGAVGSVTAMTVFFPLDTARLRLQVDEKRKSKTTHAVLLEIIKEEGLLAPYRGWFPVISSLCCSNFVYFYTFNSLKAVWVKGQRSSTGKDLVVGFVAGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIIPTNYKGIIDAFHQIIRDEGILALWNGTFPSLLLVFNPAIQFMFYEGLKRQLLKKRMKLSSLDVFIIGAIAKAIATTVTYPMQTVQSILRFGRHRLNPENRTLGSLRNVLSLLHQRVKRFGIMGLYKGLEAKLLQTVLTAALMFLVYEKLTAATFTVMGLKSTHKH |
arachidonic acid metabolic process ceramide biosynthetic process establishment of skin barrier hepoxilin biosynthetic process linoleic acid metabolic process lipid oxidation lipoxygenase pathway positive regulation of gene expression positive regulation of MAPK cascade positive regulation of mucus secretion protein lipidation sphingolipid metabolic process | cytosol; intracellular membrane-bounded organelle; perinuclear region of cytoplasm | arachidonate 12(R)-lipoxygenase activity arachidonate 12(S)-lipoxygenase activity arachidonate 8(R)-lipoxygenase activity catalytic activity iron ion binding linoleate 9S-lipoxygenase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | Mus musculus | Cytoplasm Dioxygenase Fatty acid metabolism Iron Lipid metabolism Metal-binding Oxidoreductase Reference proteome | MATYKVKVAT | MATYKVKVATGTDFFSGTLDSISLTIVGTQGESHKQRLNHFGRDFATGAVDDYTVQCQQDLGELIIIRLHKEPHSFLAKDPWYCNYVQICAPDCRVYHFPAYQWMDGYETLALREATGKITADDTLPILLEHRQEEIRAKKDFYHWRVFVPGLPNYVDIPSYHPPPRRCRNPNRPEWDGYIPGFPILINIKATRFLNSNLRFSFVKTASFFYRLGPMALAFKLRGLVDRKRSWKRLKDIKNIFPATKSVVSEYVAEHWTEDSFFGYQYLNGINPGLIRRCTQIPDKFPVTDEMVAPFLGEGTCLQAELERGNIYLADYRILDGIPTVELNGQQQHHCAPMCLLHFGPDGNMMPIAIQLSQTPGPDCPIFLPNDSEWDWLLAKTWVRYAEFYSHEAVAHLLESHLIGEAFCLALLRNLPMCHPLYKLLIPHTRYNVQINSIGRALLLNKGGLSARAMSLGLEGFAQVMVRGLSELTYKSLCIPNDFVERGVQDLPGYYFRDDSLAVWYAMERYVTEIITYYYPNDAAVEGDPELQCWVQEIFKECLLGRESSGFPTCLRTIPELIEYVTMVMYTCSARHAAVNSGQLEYTSWMPNFPSSMRNPPMQTKGLTTLQTYMDTLPDVKTTCIVLLVLWTLCREPDDRRPLGHFPDIHFVEEGPRRSIEAFRQNLNQISHNIRQRNKCLTLPYYYLDPVLIENSISI | arachidonic acid metabolic process ceramide biosynthetic process establishment of skin barrier hepoxilin biosynthetic process linoleic acid metabolic process lipid oxidation lipoxygenase pathway positive regulation of gene expression positive regulation of MAPK cascade positive regulation of mucus secretion protein lipidation sphingolipid metabolic process cytosol; intracellular membrane-bounded organelle; perinuclear region of cytoplasm arachidonate 12(R)-lipoxygenase activity arachidonate 12(S)-lipoxygenase activity arachidonate 8(R)-lipoxygenase activity catalytic activity iron ion binding linoleate 9S-lipoxygenase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Mus musculus Cytoplasm Dioxygenase Fatty acid metabolism Iron Lipid metabolism Metal-binding Oxidoreductase Reference proteome MATYKVKVAT MATYKVKVATGTDFFSGTLDSISLTIVGTQGESHKQRLNHFGRDFATGAVDDYTVQCQQDLGELIIIRLHKEPHSFLAKDPWYCNYVQICAPDCRVYHFPAYQWMDGYETLALREATGKITADDTLPILLEHRQEEIRAKKDFYHWRVFVPGLPNYVDIPSYHPPPRRCRNPNRPEWDGYIPGFPILINIKATRFLNSNLRFSFVKTASFFYRLGPMALAFKLRGLVDRKRSWKRLKDIKNIFPATKSVVSEYVAEHWTEDSFFGYQYLNGINPGLIRRCTQIPDKFPVTDEMVAPFLGEGTCLQAELERGNIYLADYRILDGIPTVELNGQQQHHCAPMCLLHFGPDGNMMPIAIQLSQTPGPDCPIFLPNDSEWDWLLAKTWVRYAEFYSHEAVAHLLESHLIGEAFCLALLRNLPMCHPLYKLLIPHTRYNVQINSIGRALLLNKGGLSARAMSLGLEGFAQVMVRGLSELTYKSLCIPNDFVERGVQDLPGYYFRDDSLAVWYAMERYVTEIITYYYPNDAAVEGDPELQCWVQEIFKECLLGRESSGFPTCLRTIPELIEYVTMVMYTCSARHAAVNSGQLEYTSWMPNFPSSMRNPPMQTKGLTTLQTYMDTLPDVKTTCIVLLVLWTLCREPDDRRPLGHFPDIHFVEEGPRRSIEAFRQNLNQISHNIRQRNKCLTLPYYYLDPVLIENSISI |
negative regulation of microtubule depolymerization positive regulation of stress-activated MAPK cascade protein localization to microtubule regulation of microtubule cytoskeleton organization | centriolar satellite; cytoplasm; cytoplasmic microtubule; cytosol; Golgi apparatus; microtubule; microtubule cytoskeleton | enzyme binding identical protein binding microtubule binding phosphoprotein binding protein homodimerization activity transferase activity ubiquitin protein ligase binding zinc ion binding | Mus musculus | Alternative splicing Coiled coil Cytoplasm Cytoskeleton Metal-binding Microtubule Phosphoprotein Reference proteome Repeat Transferase Ubl conjugation pathway Zinc Zinc-finger | METLESELTC | METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNEPVESINAFQCPTCRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMSSAEKVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVIRLRKLAQQIANCKQCLERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYLTAPNPPAIREELCTASYDTITVHWTSEDEFSVVSYELQYTIFTGQANVVNVACDGTCLLGSAGLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFTVKAINQAGSRSSEPGKLKTNSQPFRLDPKSAHRKLKVSHDNLTVERDESSSKKSHAPERFAGQGSYGVAGNVFIDSGRHYWEVVTSGSTWYAIGLAYRSAPKHEWIGKNAASWALCRCHNHWAVRHDGKETPIAPAPHLRRVGVLLDYDNGSIAFYDALSSVHLHTFHAALAQPVCPTFTVWNKCLTIVTGLPIPDHLDCTEQRP | negative regulation of microtubule depolymerization positive regulation of stress-activated MAPK cascade protein localization to microtubule regulation of microtubule cytoskeleton organization centriolar satellite; cytoplasm; cytoplasmic microtubule; cytosol; Golgi apparatus; microtubule; microtubule cytoskeleton enzyme binding identical protein binding microtubule binding phosphoprotein binding protein homodimerization activity transferase activity ubiquitin protein ligase binding zinc ion binding Mus musculus Alternative splicing Coiled coil Cytoplasm Cytoskeleton Metal-binding Microtubule Phosphoprotein Reference proteome Repeat Transferase Ubl conjugation pathway Zinc Zinc-finger METLESELTC METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNEPVESINAFQCPTCRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMSSAEKVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVIRLRKLAQQIANCKQCLERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYLTAPNPPAIREELCTASYDTITVHWTSEDEFSVVSYELQYTIFTGQANVVNVACDGTCLLGSAGLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFTVKAINQAGSRSSEPGKLKTNSQPFRLDPKSAHRKLKVSHDNLTVERDESSSKKSHAPERFAGQGSYGVAGNVFIDSGRHYWEVVTSGSTWYAIGLAYRSAPKHEWIGKNAASWALCRCHNHWAVRHDGKETPIAPAPHLRRVGVLLDYDNGSIAFYDALSSVHLHTFHAALAQPVCPTFTVWNKCLTIVTGLPIPDHLDCTEQRP |
axonogenesis cell differentiation DNA-templated transcription epithelial cell proliferation lung development negative regulation of epithelial cell proliferation positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II respiratory tube development transcription by RNA polymerase II | nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific double-stranded DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA binding | Mus musculus | Developmental protein DNA-binding Homeobox Nucleus Reference proteome | MATSGRLGFT | MATSGRLGFTVRSLLNLPEQDAKPRVRREQQTCVPQTAAWLESECSHYLSSDESGLETSPADSSQLASLRRESPGSDPEKRRKRRVLFSKAQTLELERRFRQQRYLSAPEREQLARLLRLTPTQVKIWFQNHRYKLKRGRAPGITEPSDMAASSDLHAAPGLLRRVVVPVLVHDRPPSNNGRGEGTSAVPQDKCSARLATACPVPGYTAFGPGSALGLFPAYQHLAPPALVSWNW | axonogenesis cell differentiation DNA-templated transcription epithelial cell proliferation lung development negative regulation of epithelial cell proliferation positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II respiratory tube development transcription by RNA polymerase II nucleus DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific double-stranded DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA binding Mus musculus Developmental protein DNA-binding Homeobox Nucleus Reference proteome MATSGRLGFT MATSGRLGFTVRSLLNLPEQDAKPRVRREQQTCVPQTAAWLESECSHYLSSDESGLETSPADSSQLASLRRESPGSDPEKRRKRRVLFSKAQTLELERRFRQQRYLSAPEREQLARLLRLTPTQVKIWFQNHRYKLKRGRAPGITEPSDMAASSDLHAAPGLLRRVVVPVLVHDRPPSNNGRGEGTSAVPQDKCSARLATACPVPGYTAFGPGSALGLFPAYQHLAPPALVSWNW |
neuron differentiation synaptic signaling | basal plasma membrane; cytoplasm; dendrite; inhibitory synapse; nucleus; plasma membrane; postsynaptic density; synapse | DNA binding phosphatase binding zinc ion binding | Mus musculus | Acetylation Alternative splicing Cell membrane Cell projection Coiled coil Cytoplasm Membrane Metal-binding Nucleus Phosphoprotein Reference proteome Synapse Zinc Zinc-finger | MIEEGGNKRK | MIEEGGNKRKTMAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHSTEISVSRLETVISSIYYQLNKRLPSTHQISVEQSISLLLNFMVAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYIFSQMSDSNGLMMFGKLDQFLKEALKLPTAVFEGPSFGYTEHAVRTCFPQQKKIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCHCESMMGFRYRCQQCHNYQLCQNCFWRGHASGAHSNQHQMKEHSSWKSPAKKLSHAISKSLGCVPSREPPHPVFPEQPEKPLDLAHLVPPRPLTNMNDTVVSHMSSGVPTPTKRLQYSQDMPNLLADEHALIASYVARLQHCTRVLDSPSRLDEEHRLIARYAARLAAEAGNMTRPPTDASFNFDANKQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPMLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKAQATGSPHTSPTHGGGRPMPMPVRSTSAGSTPTHGPQDSLSGVGGDVQEAFAQGTRRNLRNDLLVAADSITNTMSSLVKELHSGAEAEEQAGTEKTREGLPPRGTFLSVFLLHTWTKLAGCQTHSTSRERSQAYGKWGGTA | neuron differentiation synaptic signaling basal plasma membrane; cytoplasm; dendrite; inhibitory synapse; nucleus; plasma membrane; postsynaptic density; synapse DNA binding phosphatase binding zinc ion binding Mus musculus Acetylation Alternative splicing Cell membrane Cell projection Coiled coil Cytoplasm Membrane Metal-binding Nucleus Phosphoprotein Reference proteome Synapse Zinc Zinc-finger MIEEGGNKRK MIEEGGNKRKTMAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHSTEISVSRLETVISSIYYQLNKRLPSTHQISVEQSISLLLNFMVAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYIFSQMSDSNGLMMFGKLDQFLKEALKLPTAVFEGPSFGYTEHAVRTCFPQQKKIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCHCESMMGFRYRCQQCHNYQLCQNCFWRGHASGAHSNQHQMKEHSSWKSPAKKLSHAISKSLGCVPSREPPHPVFPEQPEKPLDLAHLVPPRPLTNMNDTVVSHMSSGVPTPTKRLQYSQDMPNLLADEHALIASYVARLQHCTRVLDSPSRLDEEHRLIARYAARLAAEAGNMTRPPTDASFNFDANKQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPMLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKAQATGSPHTSPTHGGGRPMPMPVRSTSAGSTPTHGPQDSLSGVGGDVQEAFAQGTRRNLRNDLLVAADSITNTMSSLVKELHSGAEAEEQAGTEKTREGLPPRGTFLSVFLLHTWTKLAGCQTHSTSRERSQAYGKWGGTA |
calcium ion import establishment of localization in cell negative regulation of cell-matrix adhesion negative regulation of cellular response to growth factor stimulus negative regulation of keratinocyte proliferation negative regulation of wound healing phosphorylation positive regulation of calcium ion import positive regulation of dendritic spine morphogenesis positive regulation of insulin secretion positive regulation of transcription by RNA polymerase II protein localization to plasma membrane regulation of neurotransmitter secretion regulation of synaptic vesicle exocytosis regulation of transcription by RNA polymerase II | apical dendrite; basement membrane; basolateral plasma membrane; cell-cell junction; ciliary membrane; cytoplasm; cytosol; dendrite; membrane; neuronal cell body; nuclear lamina; nuclear matrix; nucleolus; nucleus; perinuclear region of cytoplasm; plasma membrane; podocyte foot; presynaptic membrane; protein-containing complex; Schaffer collateral - CA1 synapse; synapse; synaptic membrane; vesicle | ATP binding calmodulin binding neurexin family protein binding PDZ domain binding protein kinase C binding protein serine kinase activity protein serine/threonine kinase activity protein-containing complex binding signaling receptor binding | Mus musculus | 3D-structure Alternative splicing ATP-binding Calmodulin-binding Cell membrane Cytoplasm Kinase Membrane Nucleotide-binding Nucleus Phosphoprotein Reference proteome Repeat Serine/threonine-protein kinase SH3 domain Transferase | MADDDVLFED | MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVSSHKFNSFYGDPPEELPDFSEDPTSSGLLAAERAVSQVLDSLEEIHALTDCSEKDLDFLHSVFQDQHLHTLLDLYDKINTKSSPQIRNPPSDAVQRAKEVLEEISCYPENNDAKELKRILTQPHFMALLQTHDVVAHEVYSDEALRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCERDSPSTSRQSPANGHSSTNNSVSDLPSTTQPKGRQIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSPELQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHNAVFDQLDLVTYEEVVKLPAFKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEFAPFVVFIAAPTITPGLNEDESLQRLQKESDVLQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTAPQWVPVSWVY | calcium ion import establishment of localization in cell negative regulation of cell-matrix adhesion negative regulation of cellular response to growth factor stimulus negative regulation of keratinocyte proliferation negative regulation of wound healing phosphorylation positive regulation of calcium ion import positive regulation of dendritic spine morphogenesis positive regulation of insulin secretion positive regulation of transcription by RNA polymerase II protein localization to plasma membrane regulation of neurotransmitter secretion regulation of synaptic vesicle exocytosis regulation of transcription by RNA polymerase II apical dendrite; basement membrane; basolateral plasma membrane; cell-cell junction; ciliary membrane; cytoplasm; cytosol; dendrite; membrane; neuronal cell body; nuclear lamina; nuclear matrix; nucleolus; nucleus; perinuclear region of cytoplasm; plasma membrane; podocyte foot; presynaptic membrane; protein-containing complex; Schaffer collateral - CA1 synapse; synapse; synaptic membrane; vesicle ATP binding calmodulin binding neurexin family protein binding PDZ domain binding protein kinase C binding protein serine kinase activity protein serine/threonine kinase activity protein-containing complex binding signaling receptor binding Mus musculus 3D-structure Alternative splicing ATP-binding Calmodulin-binding Cell membrane Cytoplasm Kinase Membrane Nucleotide-binding Nucleus Phosphoprotein Reference proteome Repeat Serine/threonine-protein kinase SH3 domain Transferase MADDDVLFED MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVSSHKFNSFYGDPPEELPDFSEDPTSSGLLAAERAVSQVLDSLEEIHALTDCSEKDLDFLHSVFQDQHLHTLLDLYDKINTKSSPQIRNPPSDAVQRAKEVLEEISCYPENNDAKELKRILTQPHFMALLQTHDVVAHEVYSDEALRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCERDSPSTSRQSPANGHSSTNNSVSDLPSTTQPKGRQIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSPELQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHNAVFDQLDLVTYEEVVKLPAFKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEFAPFVVFIAAPTITPGLNEDESLQRLQKESDVLQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTAPQWVPVSWVY |
chaperone-mediated protein folding negative regulation of ER-associated ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-dependent protein catabolic process positive regulation of ER-associated ubiquitin-dependent protein catabolic process post-translational protein targeting to endoplasmic reticulum membrane protein heterooligomerization protein homooligomerization tail-anchored membrane protein insertion into ER membrane ubiquitin-dependent ERAD pathway | cytosol; extrinsic component of synaptic vesicle membrane; membrane; nucleus; presynapse; TRC complex | BAT3 complex binding identical protein binding molecular adaptor activity protein self-association | Rattus norvegicus | Acetylation Chaperone Cytoplasm Direct protein sequencing Nucleus Phosphoprotein Reference proteome Repeat TPR repeat | MDNRKRLAYA | MDNRKRLAYAIIQFLHGQLRHGGLSSDAQESLEVAIQCLETAFGVTLEDSDLALPQTLPEIFEAATASKEMPQDPRGPDRTPPSEEDSAEAERLKTEGNEQMKLENFEAAVHLYGKAIELNPANAVYFCNRAAAYSKLGNYVGAVQDCERAIGIDPGYSKAYGRMGLALSSLNKHAEAVAYYKKALELDPDNDTYKSNLKIAELKLREAPSPTGGVGSLDIAGLLNNPHFITMASSLMNSPQLQQLMSGMISGGHNPLGTPGSSPQHSDLASLIQAGQQFAQQMQQQNPEFVEQIRSQVVRSRTPSASHEEQQE | chaperone-mediated protein folding negative regulation of ER-associated ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-dependent protein catabolic process positive regulation of ER-associated ubiquitin-dependent protein catabolic process post-translational protein targeting to endoplasmic reticulum membrane protein heterooligomerization protein homooligomerization tail-anchored membrane protein insertion into ER membrane ubiquitin-dependent ERAD pathway cytosol; extrinsic component of synaptic vesicle membrane; membrane; nucleus; presynapse; TRC complex BAT3 complex binding identical protein binding molecular adaptor activity protein self-association Rattus norvegicus Acetylation Chaperone Cytoplasm Direct protein sequencing Nucleus Phosphoprotein Reference proteome Repeat TPR repeat MDNRKRLAYA MDNRKRLAYAIIQFLHGQLRHGGLSSDAQESLEVAIQCLETAFGVTLEDSDLALPQTLPEIFEAATASKEMPQDPRGPDRTPPSEEDSAEAERLKTEGNEQMKLENFEAAVHLYGKAIELNPANAVYFCNRAAAYSKLGNYVGAVQDCERAIGIDPGYSKAYGRMGLALSSLNKHAEAVAYYKKALELDPDNDTYKSNLKIAELKLREAPSPTGGVGSLDIAGLLNNPHFITMASSLMNSPQLQQLMSGMISGGHNPLGTPGSSPQHSDLASLIQAGQQFAQQMQQQNPEFVEQIRSQVVRSRTPSASHEEQQE |
(R)-carnitine transmembrane transport (R)-carnitine transport adult heart development carnitine metabolic process carnitine transport establishment of localization in cell locomotory behavior mitochondrion organization positive regulation of intestinal epithelial structure maintenance quaternary ammonium group transport reproductive structure development response to tumor necrosis factor response to type II interferon sodium ion transport sodium-dependent organic cation transport transport across blood-brain barrier | apical plasma membrane; basal plasma membrane; basolateral plasma membrane; brush border membrane; cytoplasm; cytosol; plasma membrane | (R)-carnitine transmembrane transporter activity amino-acid betaine transmembrane transporter activity ATP binding carnitine transmembrane transporter activity PDZ domain binding quaternary ammonium group transmembrane transporter activity symporter activity | Rattus norvegicus | ATP-binding Cell membrane Glycoprotein Ion transport Membrane Nucleotide-binding Phosphoprotein Reference proteome Sodium Sodium transport Symport Transmembrane Transmembrane helix Transport | MRDYDEVTAF | MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFNGMSIVFLAGTPEHRCLVPHTVNLSSAWRNHSIPLETKDGRQVPQSCRRYRLATIANFSALGLEPGRDVDLEQLEQENCLDGWEYNKDVFLSTIVTEWDLVCKDDWKAPLTTSLFFVGVLMGSFISGQLSDRFGRKNVLFLTMGMQTGFSFLQLFSVNFEMFTVLFVLVGMGQISNYVAAFVLGTEILSKSIRIIFATLGVCIFYAFGFMVLPLFAYFIRDWRMLLLALTVPGVLCGALWWFIPESPRWLISQGRVKEAEVIIRKAAKFNGIVAPSTIFDPSELQDLNSKKPQSHHIYDLVRTRNIRIITIMSIILWLTISVGYFGLSLDTPNLHGDIYVNCFLLAAVEVPAYVLAWLLLQHLPRRYSISAALFLGGSVLLFIQLVPSELFYLSTALVMVGKFGITSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTILTAILTLFFPESFGAPLPDTIDQMLRVKGIKQWQIQSQTRTQKDGGESPTVLKSTAF | (R)-carnitine transmembrane transport (R)-carnitine transport adult heart development carnitine metabolic process carnitine transport establishment of localization in cell locomotory behavior mitochondrion organization positive regulation of intestinal epithelial structure maintenance quaternary ammonium group transport reproductive structure development response to tumor necrosis factor response to type II interferon sodium ion transport sodium-dependent organic cation transport transport across blood-brain barrier apical plasma membrane; basal plasma membrane; basolateral plasma membrane; brush border membrane; cytoplasm; cytosol; plasma membrane (R)-carnitine transmembrane transporter activity amino-acid betaine transmembrane transporter activity ATP binding carnitine transmembrane transporter activity PDZ domain binding quaternary ammonium group transmembrane transporter activity symporter activity Rattus norvegicus ATP-binding Cell membrane Glycoprotein Ion transport Membrane Nucleotide-binding Phosphoprotein Reference proteome Sodium Sodium transport Symport Transmembrane Transmembrane helix Transport MRDYDEVTAF MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFNGMSIVFLAGTPEHRCLVPHTVNLSSAWRNHSIPLETKDGRQVPQSCRRYRLATIANFSALGLEPGRDVDLEQLEQENCLDGWEYNKDVFLSTIVTEWDLVCKDDWKAPLTTSLFFVGVLMGSFISGQLSDRFGRKNVLFLTMGMQTGFSFLQLFSVNFEMFTVLFVLVGMGQISNYVAAFVLGTEILSKSIRIIFATLGVCIFYAFGFMVLPLFAYFIRDWRMLLLALTVPGVLCGALWWFIPESPRWLISQGRVKEAEVIIRKAAKFNGIVAPSTIFDPSELQDLNSKKPQSHHIYDLVRTRNIRIITIMSIILWLTISVGYFGLSLDTPNLHGDIYVNCFLLAAVEVPAYVLAWLLLQHLPRRYSISAALFLGGSVLLFIQLVPSELFYLSTALVMVGKFGITSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTILTAILTLFFPESFGAPLPDTIDQMLRVKGIKQWQIQSQTRTQKDGGESPTVLKSTAF |
brain development cellular detoxification of cadmium ion heme metabolic process heme transmembrane transport heme transport intracellular copper ion homeostasis melanosome assembly porphyrin-containing compound biosynthetic process porphyrin-containing compound metabolic process skin development tetrapyrrole metabolic process transmembrane transport | cytosol; early endosome membrane; endolysosome membrane; endoplasmic reticulum; endoplasmic reticulum membrane; endosome; extracellular exosome; Golgi apparatus; Golgi membrane; late endosome membrane; lysosomal membrane; melanosome membrane; mitochondrial envelope; mitochondrial outer membrane; mitochondrion; multivesicular body membrane; nucleoplasm; plasma membrane; vacuolar membrane | ABC-type heme transporter activity ABC-type transporter activity ATP binding ATP hydrolysis activity efflux transmembrane transporter activity heme binding tetrapyrrole binding | Rattus norvegicus | ATP-binding Cell membrane Disulfide bond Endoplasmic reticulum Endosome Golgi apparatus Lysosome Membrane Mitochondrion Mitochondrion outer membrane Nucleotide-binding Reference proteome Secreted Translocase Transmembrane Transmembrane helix Transport | MVTVGNYCEA | MVTVGNYCEAEGPAGPAWTQNGLSPCFFYTLVPSTLMTLGVLALVLVLPCRRREVPAGTEELSWAAGPRVAPYALQLSLAILQMALPLASLAGRVGTARGVRLPGYLLLASVLESLASACGLWLLVVERSQARQSLAMGVWMKFRHSLGLLLLWTVTFAAENLVLVSWNSPQWWWSRADLGQQVQFGLWVLRYMTSGGLFILGLWAPGLRPQSYTLHVNEEDQDGGRNQGRSTDPRSTWRDLGRKLRLLSGYLWPRGSPSLQLTVLLCMGLMGLDRALNVLVPIFYRDIVNLLTSKAPWSSLAWTVTTYVFLKFLQGGGTGSTGFVSNLRTFLWIRVQQFTSRGVELRLFSHLHELSLRWHLGRRTGEVLRIVDRGTSSVTGLLSYLVFNIIPTLADIIIGIIYFSMFFNAWFGLIVFLCMSLYLILTIMVTEWRAKFRRDMNTQENATRARAVDSLLNFETVKYYNAEGYELERYREAILKFQGLEWKSTASLVLLNQTQNMVIGFGLLAGSLLCAYFVSERRLQVGDFVLFGTYITQLYMPLNWFGTYYRMIQTNFIDMENMFDLLKEETEVKDVPGAGPLRFHKGRVEFENVHFSYADGRETLQDVSFTVMPGQTVALVGPSGAGKSTILRLLFRFYDISSGCIRIDGQDISQVTQISLRSHIGVVPQDTVLFNDTIANNIRYGRVTAGDSEIQAAAQAAGIHDAILSFPEGYETQVGERGLKLSGGEKQRVAIARTILKAPDIILLDEATSALDTSNERAIQASLAKVCTNRTTIVVAHRLSTVVNADQILVIKDGCIIERGRHEALLSRGGVYAEMWQLQQQGQETVPEDS | brain development cellular detoxification of cadmium ion heme metabolic process heme transmembrane transport heme transport intracellular copper ion homeostasis melanosome assembly porphyrin-containing compound biosynthetic process porphyrin-containing compound metabolic process skin development tetrapyrrole metabolic process transmembrane transport cytosol; early endosome membrane; endolysosome membrane; endoplasmic reticulum; endoplasmic reticulum membrane; endosome; extracellular exosome; Golgi apparatus; Golgi membrane; late endosome membrane; lysosomal membrane; melanosome membrane; mitochondrial envelope; mitochondrial outer membrane; mitochondrion; multivesicular body membrane; nucleoplasm; plasma membrane; vacuolar membrane ABC-type heme transporter activity ABC-type transporter activity ATP binding ATP hydrolysis activity efflux transmembrane transporter activity heme binding tetrapyrrole binding Rattus norvegicus ATP-binding Cell membrane Disulfide bond Endoplasmic reticulum Endosome Golgi apparatus Lysosome Membrane Mitochondrion Mitochondrion outer membrane Nucleotide-binding Reference proteome Secreted Translocase Transmembrane Transmembrane helix Transport MVTVGNYCEA MVTVGNYCEAEGPAGPAWTQNGLSPCFFYTLVPSTLMTLGVLALVLVLPCRRREVPAGTEELSWAAGPRVAPYALQLSLAILQMALPLASLAGRVGTARGVRLPGYLLLASVLESLASACGLWLLVVERSQARQSLAMGVWMKFRHSLGLLLLWTVTFAAENLVLVSWNSPQWWWSRADLGQQVQFGLWVLRYMTSGGLFILGLWAPGLRPQSYTLHVNEEDQDGGRNQGRSTDPRSTWRDLGRKLRLLSGYLWPRGSPSLQLTVLLCMGLMGLDRALNVLVPIFYRDIVNLLTSKAPWSSLAWTVTTYVFLKFLQGGGTGSTGFVSNLRTFLWIRVQQFTSRGVELRLFSHLHELSLRWHLGRRTGEVLRIVDRGTSSVTGLLSYLVFNIIPTLADIIIGIIYFSMFFNAWFGLIVFLCMSLYLILTIMVTEWRAKFRRDMNTQENATRARAVDSLLNFETVKYYNAEGYELERYREAILKFQGLEWKSTASLVLLNQTQNMVIGFGLLAGSLLCAYFVSERRLQVGDFVLFGTYITQLYMPLNWFGTYYRMIQTNFIDMENMFDLLKEETEVKDVPGAGPLRFHKGRVEFENVHFSYADGRETLQDVSFTVMPGQTVALVGPSGAGKSTILRLLFRFYDISSGCIRIDGQDISQVTQISLRSHIGVVPQDTVLFNDTIANNIRYGRVTAGDSEIQAAAQAAGIHDAILSFPEGYETQVGERGLKLSGGEKQRVAIARTILKAPDIILLDEATSALDTSNERAIQASLAKVCTNRTTIVVAHRLSTVVNADQILVIKDGCIIERGRHEALLSRGGVYAEMWQLQQQGQETVPEDS |
brown fat cell differentiation peroxisome fission peroxisome membrane biogenesis peroxisome organization regulation of peroxisome size signal transduction | peroxisomal membrane; peroxisome; protein-containing complex | protein homodimerization activity | Rattus norvegicus | Membrane Peroxisome Peroxisome biogenesis Reference proteome Transmembrane Transmembrane helix | MDAFIRVANQ | MDAFIRVANQSQGRDRLFRATQHACMLLRYLLESKAGKEAVVTKLKNLETSVSTGRKWFRLGNVLHAIQATEQSIQATDLVPRLCLTLANLNRVVYYICDTVLWAKSVGLTSGINREKWQMRAARHYYYFLLLSLVRDLYEVLLHMGQVARDRAKREKSSGDPPKYSVANEESEWLQSFLLLLFQSLKRNPPLFLDTVKNFCDILIPLNQLGIYKSNLGVVGFGGLVSSVAGLITVVYPQLKLKAR | brown fat cell differentiation peroxisome fission peroxisome membrane biogenesis peroxisome organization regulation of peroxisome size signal transduction peroxisomal membrane; peroxisome; protein-containing complex protein homodimerization activity Rattus norvegicus Membrane Peroxisome Peroxisome biogenesis Reference proteome Transmembrane Transmembrane helix MDAFIRVANQ MDAFIRVANQSQGRDRLFRATQHACMLLRYLLESKAGKEAVVTKLKNLETSVSTGRKWFRLGNVLHAIQATEQSIQATDLVPRLCLTLANLNRVVYYICDTVLWAKSVGLTSGINREKWQMRAARHYYYFLLLSLVRDLYEVLLHMGQVARDRAKREKSSGDPPKYSVANEESEWLQSFLLLLFQSLKRNPPLFLDTVKNFCDILIPLNQLGIYKSNLGVVGFGGLVSSVAGLITVVYPQLKLKAR |
CD4-positive, alpha-beta T cell activation CD4-positive, alpha-beta T cell differentiation defense response to virus innate immune response negative regulation of protein secretion negative regulation of viral genome replication ossification positive regulation of immune response positive regulation of T-helper 2 cell cytokine production positive regulation of toll-like receptor 7 signaling pathway positive regulation of toll-like receptor 9 signaling pathway regulation of ossification response to virus | endoplasmic reticulum; endoplasmic reticulum membrane; Golgi apparatus; lipid droplet; mitochondrial inner membrane; mitochondrial outer membrane; mitochondrion | 4 iron, 4 sulfur cluster binding lyase activity metal ion binding protein self-association | Rattus norvegicus | 4Fe-4S Acetylation Antiviral defense Endoplasmic reticulum Golgi apparatus Immunity Innate immunity Iron Iron-sulfur Isopeptide bond Lipid droplet Lyase Membrane Metal-binding Mitochondrion Mitochondrion inner membrane Mitochondrion outer membrane Reference proteome S-adenosyl-L-methionine Ubl conjugation | MLVPTALAAR | MLVPTALAARLLSLFQQQLGSLWSGLAMLFCWLRIALGWPDPGKGQPRVRGEPKETQETHEDPGSAQPTTPVSVNYHFTRQCNYKCGFCFHTAKTSFVLPLEEAKRGLLLLKQAGMEKINFSGGEPFLQDRGEYLGKLVRFCKEELALPSVSIVSNGSLIRERWFKDYGDYLDILAISCDSFDEQVNVLIGRGQGKKNHVENLQKLRKWCRDYKVAFKINSVINRFNVDEDMNEHIKALSPVRWKVFQCLLIEGENSGEDALREAERFLISNEEFEAFLQRHKDVSCLVPESNQKMKDSYLILDEYMRFLNCTGGRKDPSRSILDVGVEEAIKFSGFDEKMFLKRGGKYVWSKADLKLDW | CD4-positive, alpha-beta T cell activation CD4-positive, alpha-beta T cell differentiation defense response to virus innate immune response negative regulation of protein secretion negative regulation of viral genome replication ossification positive regulation of immune response positive regulation of T-helper 2 cell cytokine production positive regulation of toll-like receptor 7 signaling pathway positive regulation of toll-like receptor 9 signaling pathway regulation of ossification response to virus endoplasmic reticulum; endoplasmic reticulum membrane; Golgi apparatus; lipid droplet; mitochondrial inner membrane; mitochondrial outer membrane; mitochondrion 4 iron, 4 sulfur cluster binding lyase activity metal ion binding protein self-association Rattus norvegicus 4Fe-4S Acetylation Antiviral defense Endoplasmic reticulum Golgi apparatus Immunity Innate immunity Iron Iron-sulfur Isopeptide bond Lipid droplet Lyase Membrane Metal-binding Mitochondrion Mitochondrion inner membrane Mitochondrion outer membrane Reference proteome S-adenosyl-L-methionine Ubl conjugation MLVPTALAAR MLVPTALAARLLSLFQQQLGSLWSGLAMLFCWLRIALGWPDPGKGQPRVRGEPKETQETHEDPGSAQPTTPVSVNYHFTRQCNYKCGFCFHTAKTSFVLPLEEAKRGLLLLKQAGMEKINFSGGEPFLQDRGEYLGKLVRFCKEELALPSVSIVSNGSLIRERWFKDYGDYLDILAISCDSFDEQVNVLIGRGQGKKNHVENLQKLRKWCRDYKVAFKINSVINRFNVDEDMNEHIKALSPVRWKVFQCLLIEGENSGEDALREAERFLISNEEFEAFLQRHKDVSCLVPESNQKMKDSYLILDEYMRFLNCTGGRKDPSRSILDVGVEEAIKFSGFDEKMFLKRGGKYVWSKADLKLDW |
adaptive immune response calcium-mediated signaling gene expression homeostasis of number of cells immune response inflammatory response integrin-mediated signaling pathway intracellular signal transduction lymphocyte homeostasis mast cell degranulation Ras protein signal transduction regulation of T cell activation T cell receptor signaling pathway | cell-cell junction; COP9 signalosome; immunological synapse; membrane; plasma membrane | protein kinase binding signaling receptor complex adaptor activity | Rattus norvegicus | Adaptive immunity Cell membrane Immunity Lipoprotein Mast cell degranulation Membrane Palmitate Phosphoprotein Reference proteome Signal-anchor Transmembrane Transmembrane helix Ubl conjugation | MEADALSPVE | MEADALSPVELGLLLLPFVVMLLAALCVRCRELPASYDSASTESLYPRSILIKPPQITVPRTPATSYPLVTSFPPLRQPDLLPIPRSPQPLGGSHRMPSSRQNSDDANSVASYENQEPARKNVDEDEDEDDYPEGYLVVLPDSSPAAVPVVSSAPVPSNPDLGDSAFSMESCEDYVNVPESEESAEASLDGSREYVNVSQDAQPVIRAELASVTSQEVEDEEEEDVDGEEAPDYENLQELN | adaptive immune response calcium-mediated signaling gene expression homeostasis of number of cells immune response inflammatory response integrin-mediated signaling pathway intracellular signal transduction lymphocyte homeostasis mast cell degranulation Ras protein signal transduction regulation of T cell activation T cell receptor signaling pathway cell-cell junction; COP9 signalosome; immunological synapse; membrane; plasma membrane protein kinase binding signaling receptor complex adaptor activity Rattus norvegicus Adaptive immunity Cell membrane Immunity Lipoprotein Mast cell degranulation Membrane Palmitate Phosphoprotein Reference proteome Signal-anchor Transmembrane Transmembrane helix Ubl conjugation MEADALSPVE MEADALSPVELGLLLLPFVVMLLAALCVRCRELPASYDSASTESLYPRSILIKPPQITVPRTPATSYPLVTSFPPLRQPDLLPIPRSPQPLGGSHRMPSSRQNSDDANSVASYENQEPARKNVDEDEDEDDYPEGYLVVLPDSSPAAVPVVSSAPVPSNPDLGDSAFSMESCEDYVNVPESEESAEASLDGSREYVNVSQDAQPVIRAELASVTSQEVEDEEEEDVDGEEAPDYENLQELN |
bone development clustering of voltage-gated sodium channels ERBB2-ERBB3 signaling pathway myelination in peripheral nervous system negative regulation of cell-matrix adhesion negative regulation of Rho protein signal transduction negative regulation of stress fiber assembly neuron projection development non-canonical Wnt signaling pathway osteoblast differentiation positive regulation of cell migration positive regulation of focal adhesion assembly positive regulation of JNK cascade positive regulation of mitochondrial depolarization positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of stress fiber assembly positive regulation of substrate adhesion-dependent cell spreading regulation of MAPK cascade signal transduction skeletal muscle hypertrophy | cilium; collagen-containing extracellular matrix; cytoplasmic vesicle; endoplasmic reticulum; extracellular exosome; extracellular space; Golgi apparatus; mesaxon; mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrial outer membrane; myelin sheath abaxonal region; node of Ranvier; rough endoplasmic reticulum; Schmidt-Lanterman incisure | fibronectin binding frizzled binding metal ion binding myosin light chain binding receptor tyrosine kinase binding | Mus musculus | 3D-structure Calcium Cell projection Cilium Coiled coil Cytoplasmic vesicle Disulfide bond Endoplasmic reticulum Extracellular matrix Glycoprotein Golgi apparatus Lipoprotein Membrane Metal-binding Mitochondrion Mitochondrion inner membrane Mitochondrion outer membrane Palmitate Reference proteome Secreted Signal | MPALHLLFLA | MPALHLLFLACLVWGMGARTAQFRKANDRSGRCQYTFTVASPNESSCPREDQAMSAIQDLQRDSSIQHADLESTKARVRSLESLLHQMTLGRVTGTQEAQEGLQGQLGALRRERDQLETQTRDLEAAYNNLLRDKSALEEEKRQLEQENEDLARRLESSSEEVTRLRRGQCPSTQYPSQDMLPGSREVSQWNLDTLAFQELKSELTEVPASQILKENPSGRPRSKEGDKGCGALVWVGEPVTLRTAETIAGKYGVWMRDPKPTHPYTQESTWRIDTVGTEIRQVFEYSQISQFEQGYPSKVHVLPRALESTGAVVYAGSLYFQGAESRTVVRYELDTETVKAEKEIPGAGYHGHFPYAWGGYTDIDLAVDESGLWVIYSTEEAKGAIVLSKLNPANLELERTWETNIRKQSVANAFVICGILYTVSSYSSAHATVNFAYDTKTGTSKTLTIPFTNRYKYSSMIDYNPLERKLFAWDNFNMVTYDIKLLEM | bone development clustering of voltage-gated sodium channels ERBB2-ERBB3 signaling pathway myelination in peripheral nervous system negative regulation of cell-matrix adhesion negative regulation of Rho protein signal transduction negative regulation of stress fiber assembly neuron projection development non-canonical Wnt signaling pathway osteoblast differentiation positive regulation of cell migration positive regulation of focal adhesion assembly positive regulation of JNK cascade positive regulation of mitochondrial depolarization positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of stress fiber assembly positive regulation of substrate adhesion-dependent cell spreading regulation of MAPK cascade signal transduction skeletal muscle hypertrophy cilium; collagen-containing extracellular matrix; cytoplasmic vesicle; endoplasmic reticulum; extracellular exosome; extracellular space; Golgi apparatus; mesaxon; mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrial outer membrane; myelin sheath abaxonal region; node of Ranvier; rough endoplasmic reticulum; Schmidt-Lanterman incisure fibronectin binding frizzled binding metal ion binding myosin light chain binding receptor tyrosine kinase binding Mus musculus 3D-structure Calcium Cell projection Cilium Coiled coil Cytoplasmic vesicle Disulfide bond Endoplasmic reticulum Extracellular matrix Glycoprotein Golgi apparatus Lipoprotein Membrane Metal-binding Mitochondrion Mitochondrion inner membrane Mitochondrion outer membrane Palmitate Reference proteome Secreted Signal MPALHLLFLA MPALHLLFLACLVWGMGARTAQFRKANDRSGRCQYTFTVASPNESSCPREDQAMSAIQDLQRDSSIQHADLESTKARVRSLESLLHQMTLGRVTGTQEAQEGLQGQLGALRRERDQLETQTRDLEAAYNNLLRDKSALEEEKRQLEQENEDLARRLESSSEEVTRLRRGQCPSTQYPSQDMLPGSREVSQWNLDTLAFQELKSELTEVPASQILKENPSGRPRSKEGDKGCGALVWVGEPVTLRTAETIAGKYGVWMRDPKPTHPYTQESTWRIDTVGTEIRQVFEYSQISQFEQGYPSKVHVLPRALESTGAVVYAGSLYFQGAESRTVVRYELDTETVKAEKEIPGAGYHGHFPYAWGGYTDIDLAVDESGLWVIYSTEEAKGAIVLSKLNPANLELERTWETNIRKQSVANAFVICGILYTVSSYSSAHATVNFAYDTKTGTSKTLTIPFTNRYKYSSMIDYNPLERKLFAWDNFNMVTYDIKLLEM |
cGMP catabolic process cGMP metabolic process negative regulation of neural precursor cell proliferation positive regulation of cardiac muscle hypertrophy positive regulation of long-term synaptic potentiation signal transduction | cytosol; endoplasmic reticulum; Golgi apparatus; nucleoplasm; perikaryon; perinuclear region of cytoplasm; plasma membrane; ruffle membrane; sarcolemma | 3',5'-cyclic-GMP phosphodiesterase activity identical protein binding metal ion binding | Mus musculus | Alternative splicing Cell membrane Cell projection cGMP Cytoplasm Endoplasmic reticulum Golgi apparatus Hydrolase Magnesium Membrane Metal-binding Phosphoprotein Reference proteome Zinc | MGAGSSSYRP | MGAGSSSYRPKAIYLDIDGRIQKVVFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAMVSIDPTMPANSERTPYKVRPVAVKQVSEREELIQGVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARNSRTNCPCKYSFLDNKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPITLRRWLLCVHDNYRNNPFHNFRHCFCVTQMMYSMVWLCGLQEKFSQMDILVLMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAIAFQILARPECNIFASVPPEGFRQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHLTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPVVEETMLRPLWESREHYEELKQLDDAMKELQKKTESLTSGAPENTTEKNRDAKDSEGHSPPN | cGMP catabolic process cGMP metabolic process negative regulation of neural precursor cell proliferation positive regulation of cardiac muscle hypertrophy positive regulation of long-term synaptic potentiation signal transduction cytosol; endoplasmic reticulum; Golgi apparatus; nucleoplasm; perikaryon; perinuclear region of cytoplasm; plasma membrane; ruffle membrane; sarcolemma 3',5'-cyclic-GMP phosphodiesterase activity identical protein binding metal ion binding Mus musculus Alternative splicing Cell membrane Cell projection cGMP Cytoplasm Endoplasmic reticulum Golgi apparatus Hydrolase Magnesium Membrane Metal-binding Phosphoprotein Reference proteome Zinc MGAGSSSYRP MGAGSSSYRPKAIYLDIDGRIQKVVFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAMVSIDPTMPANSERTPYKVRPVAVKQVSEREELIQGVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARNSRTNCPCKYSFLDNKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPITLRRWLLCVHDNYRNNPFHNFRHCFCVTQMMYSMVWLCGLQEKFSQMDILVLMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAIAFQILARPECNIFASVPPEGFRQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHLTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPVVEETMLRPLWESREHYEELKQLDDAMKELQKKTESLTSGAPENTTEKNRDAKDSEGHSPPN |
retinoid metabolic process | endoplasmic reticulum; intracellular membrane-bounded organelle | acylcarnitine hydrolase activity all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity carboxylic ester hydrolase activity retinyl-palmitate esterase activity | Rattus norvegicus | Disulfide bond Endoplasmic reticulum Hydrolase Lipid metabolism Microsome Reference proteome Signal | MARKQPHSWL | MARKQPHSWLNAVLFGLLLILIHVWGQDSPESSSIRTTHTGQVRGKLDHVRDTKAGVHTFLGIPFAKAPVGPLRFAPPEDPEPWSGVRDGTSHPAMCLQNIDMLDEVGLTDMKMILSSIPMSEDCLYLNIYTPAHAHEGSNLPVMVCIHGGALVIGMASMCDGSLLAVNEDLVVVAIQYRLGVLGFFSTGDEHARGNWGYLDQVAALRWVQQNIAHFGGNPNRVTIFGVSAGGTSVSSHVISPMSQGLFHGAIMESGVALLPDLISETSETVSTTVAKLSGCEATDSETLVRCLRAKSGAEILVINKVFKMIPAVVDGEFLPRHPKELLASEDFHPVPSIIGVNTDEYCCTIPMVMGTAQIIKELSRENLQAVLKDTAAQMMLPPECGDLLMEEYMGNTDDPQTLQIQYAEMMGDFLFVIPALQVAHFQRSHAPVYFYEFQHAPSYFKNVRPPHVKADHADEVPFVFGSFFWGIKVDFTEEEKLLSRRMMKYWANFARHGNPNSEGLPYWPVLDHDEQYLQLDTQPAVDRALKARRLQFWTKTLPQKIQELNGAQKNHAEL | retinoid metabolic process endoplasmic reticulum; intracellular membrane-bounded organelle acylcarnitine hydrolase activity all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity carboxylic ester hydrolase activity retinyl-palmitate esterase activity Rattus norvegicus Disulfide bond Endoplasmic reticulum Hydrolase Lipid metabolism Microsome Reference proteome Signal MARKQPHSWL MARKQPHSWLNAVLFGLLLILIHVWGQDSPESSSIRTTHTGQVRGKLDHVRDTKAGVHTFLGIPFAKAPVGPLRFAPPEDPEPWSGVRDGTSHPAMCLQNIDMLDEVGLTDMKMILSSIPMSEDCLYLNIYTPAHAHEGSNLPVMVCIHGGALVIGMASMCDGSLLAVNEDLVVVAIQYRLGVLGFFSTGDEHARGNWGYLDQVAALRWVQQNIAHFGGNPNRVTIFGVSAGGTSVSSHVISPMSQGLFHGAIMESGVALLPDLISETSETVSTTVAKLSGCEATDSETLVRCLRAKSGAEILVINKVFKMIPAVVDGEFLPRHPKELLASEDFHPVPSIIGVNTDEYCCTIPMVMGTAQIIKELSRENLQAVLKDTAAQMMLPPECGDLLMEEYMGNTDDPQTLQIQYAEMMGDFLFVIPALQVAHFQRSHAPVYFYEFQHAPSYFKNVRPPHVKADHADEVPFVFGSFFWGIKVDFTEEEKLLSRRMMKYWANFARHGNPNSEGLPYWPVLDHDEQYLQLDTQPAVDRALKARRLQFWTKTLPQKIQELNGAQKNHAEL |
protein complex oligomerization suppression by virus of host autophagy virus-mediated pore formation in host cell membrane | host cell plasma membrane; membrane; virion membrane | identical protein binding monoatomic ion channel activity proton transmembrane transporter activity | Influenza A virus | 3D-structure Alternative splicing Disulfide bond Host cell membrane Host membrane Host-virus interaction Hydrogen ion transport Inhibition of host autophagy by virus Ion channel Ion transport Lipoprotein Membrane Palmitate Phosphoprotein Signal-anchor Transmembrane Transmembrane helix Transport Viral ion channel Virion | MSLLTEVETL | MSLLTEVETLTRNGWGCRCSDSSDPLVVAASIIGILHLILWILDRLFFKCIYRRFKYGLKRGPSTEGVPESMREEYRQEQQNAVDVDDGHFVNIELE | protein complex oligomerization suppression by virus of host autophagy virus-mediated pore formation in host cell membrane host cell plasma membrane; membrane; virion membrane identical protein binding monoatomic ion channel activity proton transmembrane transporter activity Influenza A virus 3D-structure Alternative splicing Disulfide bond Host cell membrane Host membrane Host-virus interaction Hydrogen ion transport Inhibition of host autophagy by virus Ion channel Ion transport Lipoprotein Membrane Palmitate Phosphoprotein Signal-anchor Transmembrane Transmembrane helix Transport Viral ion channel Virion MSLLTEVETL MSLLTEVETLTRNGWGCRCSDSSDPLVVAASIIGILHLILWILDRLFFKCIYRRFKYGLKRGPSTEGVPESMREEYRQEQQNAVDVDDGHFVNIELE |
DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by virus of host type I interferon-mediated signaling pathway | extracellular region; host cell cytoplasm; host cell nucleolus | actinin binding cyclin binding metal ion binding protein domain specific binding protein serine/threonine phosphatase inhibitor activity RNA-binding transcription regulator activity trans-activation response element binding | Human immunodeficiency virus type 1 group M subtype F1 | Acetylation Activator AIDS Alternative splicing Apoptosis Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Isopeptide bond Metal-binding Methylation Modulation of host chromatin by virus Modulation of host PP1 activity by virus Phosphoprotein Reference proteome RNA-binding Secreted Transcription Transcription regulation Ubl conjugation Viral immunoevasion Zinc | MELVDPNLDP | MELVDPNLDPWNHPGSQPTTPCTRCYCKWCCFHCYWCFTTKGLGISYGRKKRRQRPRTPQSSQIHQDFVPKQPISQARGNPTGPKESKKEVESKAKTDP | DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by virus of host type I interferon-mediated signaling pathway extracellular region; host cell cytoplasm; host cell nucleolus actinin binding cyclin binding metal ion binding protein domain specific binding protein serine/threonine phosphatase inhibitor activity RNA-binding transcription regulator activity trans-activation response element binding Human immunodeficiency virus type 1 group M subtype F1 Acetylation Activator AIDS Alternative splicing Apoptosis Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Isopeptide bond Metal-binding Methylation Modulation of host chromatin by virus Modulation of host PP1 activity by virus Phosphoprotein Reference proteome RNA-binding Secreted Transcription Transcription regulation Ubl conjugation Viral immunoevasion Zinc MELVDPNLDP MELVDPNLDPWNHPGSQPTTPCTRCYCKWCCFHCYWCFTTKGLGISYGRKKRRQRPRTPQSSQIHQDFVPKQPISQARGNPTGPKESKKEVESKAKTDP |
DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by virus of host type I interferon-mediated signaling pathway | extracellular region; host cell cytoplasm; host cell nucleolus | actinin binding cyclin binding metal ion binding protein domain specific binding protein serine/threonine phosphatase inhibitor activity RNA-binding transcription regulator activity trans-activation response element binding | Human immunodeficiency virus type 1 group M subtype H | Acetylation Activator AIDS Alternative splicing Apoptosis Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Isopeptide bond Metal-binding Methylation Modulation of host chromatin by virus Modulation of host PP1 activity by virus Phosphoprotein Reference proteome RNA-binding Secreted Transcription Transcription regulation Ubl conjugation Viral immunoevasion Zinc | MDPVDPKLEP | MDPVDPKLEPWNHPGSQPQTACNNCYCKKCCYHCQMCFLKKGLGISYGRKKRSQRHRTPASLQDHQNSISKQPLSRTHGDPTGPKEQKKEVASKTETDP | DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by virus of host type I interferon-mediated signaling pathway extracellular region; host cell cytoplasm; host cell nucleolus actinin binding cyclin binding metal ion binding protein domain specific binding protein serine/threonine phosphatase inhibitor activity RNA-binding transcription regulator activity trans-activation response element binding Human immunodeficiency virus type 1 group M subtype H Acetylation Activator AIDS Alternative splicing Apoptosis Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Isopeptide bond Metal-binding Methylation Modulation of host chromatin by virus Modulation of host PP1 activity by virus Phosphoprotein Reference proteome RNA-binding Secreted Transcription Transcription regulation Ubl conjugation Viral immunoevasion Zinc MDPVDPKLEP MDPVDPKLEPWNHPGSQPQTACNNCYCKKCCYHCQMCFLKKGLGISYGRKKRSQRHRTPASLQDHQNSISKQPLSRTHGDPTGPKEQKKEVASKTETDP |
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral protein processing virion attachment to host cell virus-mediated perturbation of host defense response | host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane | structural molecule activity | Human immunodeficiency virus type 1 group M subtype H | AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Palmitate Reference proteome Signal Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Viral immunoevasion Viral penetration into host cytoplasm Virion Virus endocytosis by host Virus entry into host cell | METQRNYPSL | METQRNYPSLWRWGTLILGMLLICSAAQNLWVTVYYGVPVWKEAKTTLFCASDAKAYETEKHNVWATHACVPTDPNPQEMVMENVTESFNMWENNMVEQMHTDIISLWDQSLKPCVKLTPLCVTLNCTNVRNNTSNSTSSMEAGGELTNCSFNVTTVLRDKQQKVHALFYRLDVVPIDNNSTQYRLINCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNNKTFNGTGLCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEQIIIRTKNISDNTKNIIVQLKTPVNITCTRPNNNTRTSIHLGPGRAFYATGDIIGDIRQAHCNISRTDWNKTLHQVVTQLGIHLNNRTISFKPNSGGDMEVRTHSFNCRGEFFYCNTSGLFNSSWEMHTNYTSNDTKGNENITLPCRIKQIVNMWQRVGRAMYAPPIQGNIMCVSNITGLILTIDEGNASAENYTFRPGGGDMRDNWRSELYKYKVVKIEPLGIAPTKTRRRVVEREKRAVGMGASFLGFLGAAGSTMGAASITLTVQARQLLSGIVQQQSNLLRAIQARQHMLQLTVWGIKQLQARVLAVERYLRDQQLLGIWGCSGKLICTTNVPWNSSWSNKSQSEIWDNMTWMEWDKQISNYTEEIYRLLEVSQTQQEKNEQDLLALDKWASLWTWFDISHWLWYIKIFIMIVGGLIGLRIIFAVLSIVNRVRQGYSPLSFQTLVPNPRGPDRPEGTEEGGGEQDRDRSVRLVNGFLPVVWDDLRSLSLFSYRLLRDLLLIVVRTVELLGRRGREALKYLWNLLQYWGQELKNSAIDLLNTTAIAVAEGTDGIIVIVQRAWRAILHIPRRIRQGFERSLL | clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral protein processing virion attachment to host cell virus-mediated perturbation of host defense response host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane structural molecule activity Human immunodeficiency virus type 1 group M subtype H AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Palmitate Reference proteome Signal Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Viral immunoevasion Viral penetration into host cytoplasm Virion Virus endocytosis by host Virus entry into host cell METQRNYPSL METQRNYPSLWRWGTLILGMLLICSAAQNLWVTVYYGVPVWKEAKTTLFCASDAKAYETEKHNVWATHACVPTDPNPQEMVMENVTESFNMWENNMVEQMHTDIISLWDQSLKPCVKLTPLCVTLNCTNVRNNTSNSTSSMEAGGELTNCSFNVTTVLRDKQQKVHALFYRLDVVPIDNNSTQYRLINCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNNKTFNGTGLCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEQIIIRTKNISDNTKNIIVQLKTPVNITCTRPNNNTRTSIHLGPGRAFYATGDIIGDIRQAHCNISRTDWNKTLHQVVTQLGIHLNNRTISFKPNSGGDMEVRTHSFNCRGEFFYCNTSGLFNSSWEMHTNYTSNDTKGNENITLPCRIKQIVNMWQRVGRAMYAPPIQGNIMCVSNITGLILTIDEGNASAENYTFRPGGGDMRDNWRSELYKYKVVKIEPLGIAPTKTRRRVVEREKRAVGMGASFLGFLGAAGSTMGAASITLTVQARQLLSGIVQQQSNLLRAIQARQHMLQLTVWGIKQLQARVLAVERYLRDQQLLGIWGCSGKLICTTNVPWNSSWSNKSQSEIWDNMTWMEWDKQISNYTEEIYRLLEVSQTQQEKNEQDLLALDKWASLWTWFDISHWLWYIKIFIMIVGGLIGLRIIFAVLSIVNRVRQGYSPLSFQTLVPNPRGPDRPEGTEEGGGEQDRDRSVRLVNGFLPVVWDDLRSLSLFSYRLLRDLLLIVVRTVELLGRRGREALKYLWNLLQYWGQELKNSAIDLLNTTAIAVAEGTDGIIVIVQRAWRAILHIPRRIRQGFERSLL |
suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy | extracellular region; host cell Golgi membrane; host cell plasma membrane; membrane; virion component | GTP binding SH3 domain binding | Human immunodeficiency virus type 1 group M subtype H | AIDS Apoptosis Early protein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host autophagy by virus Inhibition of host MHC class I molecule presentation by virus Inhibition of host MHC class II molecule presentation by virus Lipoprotein Membrane Myristate Phosphoprotein Reference proteome Secreted SH3-binding Viral immunoevasion Virion Virulence | MGGKWSKSRM | MGGKWSKSRMGGWSTIRERMRRAEPVAEGVGAVSRDLDRRGAVTINNTASTNRDAAWLEAQEDGEEVGFPVRPQVPLRPMTYKGAFDLSHFLKEKGGLDGLIYSKQRQDILDLWVYNTQGYFPDWQNYTPGPGERFPLTFGWCFKLVPVNPQEVEQANEGENNSLLHPMSLHGMEDDGREVLMWKFDSRLALTHLARVKHPEYKDC | suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy extracellular region; host cell Golgi membrane; host cell plasma membrane; membrane; virion component GTP binding SH3 domain binding Human immunodeficiency virus type 1 group M subtype H AIDS Apoptosis Early protein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host autophagy by virus Inhibition of host MHC class I molecule presentation by virus Inhibition of host MHC class II molecule presentation by virus Lipoprotein Membrane Myristate Phosphoprotein Reference proteome Secreted SH3-binding Viral immunoevasion Virion Virulence MGGKWSKSRM MGGKWSKSRMGGWSTIRERMRRAEPVAEGVGAVSRDLDRRGAVTINNTASTNRDAAWLEAQEDGEEVGFPVRPQVPLRPMTYKGAFDLSHFLKEKGGLDGLIYSKQRQDILDLWVYNTQGYFPDWQNYTPGPGERFPLTFGWCFKLVPVNPQEVEQANEGENNSLLHPMSLHGMEDDGREVLMWKFDSRLALTHLARVKHPEYKDC |
DNA-templated transcription proteolysis viral process | host cell membrane; membrane | nucleotide binding RNA binding RNA-dependent RNA polymerase activity serine-type endopeptidase activity | Southern bean mosaic virus | Covalent protein-RNA linkage Direct protein sequencing Host membrane Hydrolase Membrane Nucleotide-binding Nucleotidyltransferase Protease Reference proteome Ribosomal frameshifting RNA-directed RNA polymerase Serine protease Transferase Transmembrane Transmembrane helix Viral RNA replication | MYHPGRSPSF | MYHPGRSPSFLITLANVICAAILFDIHTGGYQPGSLIPIVAWMTPFVTLLWLSASFATYLYKYVRTRLLPEEKVARVYYTAQSAPYFDPALGVMMQFAPSHGGASIEVQVNPSWISLLGGSLKINGDDASNESAVLGSFYSSVKPGDEPASLVAIKSGPQTIGFGCRTKIDGDDCLFTANHVWNNSMRPTALAKRGKQVAIEDWETPLSCDHKMLDFVVVRVPKHVWSKLGVKATQLVCPSDKDAVTCYGGSSSDNLLSGTGVCSKVDFSWKLTHSCPTAAGWSGTPIYSSRGVVGMHVGFEDIGKLNRGVNAFYVSNYLLRSQETLPPELSVIEIPFEDVETRSYEFIEVEIKGRGKAKLGKREFAWIPESGKYWADDDDDSLPPPPKVVDGKMVWSSAQETVAEPLNLPAGGRVKALAALSQLAGYDFKEGEAASTRGMPLRFVGQSACKFRELCRKDTPDEVLRATRVFPELSDFSWPERGSKAELHSLLLQAGKFNPTGIPRNLEGACQNLLERYPASKSCYCLRGEAWSFDAVYEEVCKKAQSAEINEKASPGVPLSRLASTNKDLLKRHLELVALCVTERLFLLSEAEDLLDESPVDLVRRGLCDPVRLFVKQEPHASRKVREGRFRLISSVSLVDQLVERMLFGPQNQLEIAEWEHIPSKPGMGLSLRQQAKSLFDDLRVKHSRCPAAEADISGFDWSVQDWELWADVEMRIVLGGFGHKLAKAAQNRFSCFMNSVFQLSDGTLIEQQLPGIMKSGSYCTSSTNSRIRCLMAELIGSPWCIAMGDDSVEGWVDGAKDKYMRLGHTCKDYKPCATTISGRLYEVEFCSHVIREDRCWLASWPKTLFKYLSEGKWFFEDLERDVSSSPHWPRIRHYVVGNTPSPHKTNLQNQSPRYGEEVDKTTVNQGYSEHSGSPGHSIEEAQEPEAAPFCCEAASVYPGWGVHGPYCSGDYGSLT | DNA-templated transcription proteolysis viral process host cell membrane; membrane nucleotide binding RNA binding RNA-dependent RNA polymerase activity serine-type endopeptidase activity Southern bean mosaic virus Covalent protein-RNA linkage Direct protein sequencing Host membrane Hydrolase Membrane Nucleotide-binding Nucleotidyltransferase Protease Reference proteome Ribosomal frameshifting RNA-directed RNA polymerase Serine protease Transferase Transmembrane Transmembrane helix Viral RNA replication MYHPGRSPSF MYHPGRSPSFLITLANVICAAILFDIHTGGYQPGSLIPIVAWMTPFVTLLWLSASFATYLYKYVRTRLLPEEKVARVYYTAQSAPYFDPALGVMMQFAPSHGGASIEVQVNPSWISLLGGSLKINGDDASNESAVLGSFYSSVKPGDEPASLVAIKSGPQTIGFGCRTKIDGDDCLFTANHVWNNSMRPTALAKRGKQVAIEDWETPLSCDHKMLDFVVVRVPKHVWSKLGVKATQLVCPSDKDAVTCYGGSSSDNLLSGTGVCSKVDFSWKLTHSCPTAAGWSGTPIYSSRGVVGMHVGFEDIGKLNRGVNAFYVSNYLLRSQETLPPELSVIEIPFEDVETRSYEFIEVEIKGRGKAKLGKREFAWIPESGKYWADDDDDSLPPPPKVVDGKMVWSSAQETVAEPLNLPAGGRVKALAALSQLAGYDFKEGEAASTRGMPLRFVGQSACKFRELCRKDTPDEVLRATRVFPELSDFSWPERGSKAELHSLLLQAGKFNPTGIPRNLEGACQNLLERYPASKSCYCLRGEAWSFDAVYEEVCKKAQSAEINEKASPGVPLSRLASTNKDLLKRHLELVALCVTERLFLLSEAEDLLDESPVDLVRRGLCDPVRLFVKQEPHASRKVREGRFRLISSVSLVDQLVERMLFGPQNQLEIAEWEHIPSKPGMGLSLRQQAKSLFDDLRVKHSRCPAAEADISGFDWSVQDWELWADVEMRIVLGGFGHKLAKAAQNRFSCFMNSVFQLSDGTLIEQQLPGIMKSGSYCTSSTNSRIRCLMAELIGSPWCIAMGDDSVEGWVDGAKDKYMRLGHTCKDYKPCATTISGRLYEVEFCSHVIREDRCWLASWPKTLFKYLSEGKWFFEDLERDVSSSPHWPRIRHYVVGNTPSPHKTNLQNQSPRYGEEVDKTTVNQGYSEHSGSPGHSIEEAQEPEAAPFCCEAASVYPGWGVHGPYCSGDYGSLT |
viral budding from plasma membrane viral budding via host ESCRT complex | host cell perinuclear region of cytoplasm; host cell plasma membrane; membrane; virion component | RNA binding zinc ion binding | Lassa virus | 3D-structure Host cell membrane Host cytoplasm Host membrane Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Reference proteome Viral budding Viral budding via the host ESCRT complexes Viral release from host cell Virion Zinc Zinc-finger | MGNKQAKAPE | MGNKQAKAPESKDSPRASLIPDATHLGPQFCKSCWFENKGLVECNNHYLCLNCLTLLLSVSNRCPICKMPLPTKLRPSAAPTAPPTGAADSIRPPPYSP | viral budding from plasma membrane viral budding via host ESCRT complex host cell perinuclear region of cytoplasm; host cell plasma membrane; membrane; virion component RNA binding zinc ion binding Lassa virus 3D-structure Host cell membrane Host cytoplasm Host membrane Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Reference proteome Viral budding Viral budding via the host ESCRT complexes Viral release from host cell Virion Zinc Zinc-finger MGNKQAKAPE MGNKQAKAPESKDSPRASLIPDATHLGPQFCKSCWFENKGLVECNNHYLCLNCLTLLLSVSNRCPICKMPLPTKLRPSAAPTAPPTGAADSIRPPPYSP |
cellular response to glucocorticoid stimulus cellular response to steroid hormone stimulus chromatin organization positive regulation of transcription by RNA polymerase II | centrosome; cytoplasm; mitochondrion; nuclear speck; nucleus; spindle | DNA-binding transcription factor activity nuclear glucocorticoid receptor activity nuclear receptor activity sequence-specific DNA binding steroid binding steroid hormone binding zinc ion binding | Paralichthys olivaceus | Chromatin regulator Cytoplasm Cytoskeleton DNA-binding Lipid-binding Metal-binding Mitochondrion Nucleus Receptor Steroid-binding Transcription Transcription regulation Zinc Zinc-finger | MDQGGLKRNC | MDQGGLKRNCNRDDSLTFGETAVGVGSDTGDTAGSLLQPAAMHLPSPSSLPQLTVAPNGGAGTKDQGEFGGLFESPRGQCEGSEMKEGKIIRLQKRKHHLDIGMFNMEDNLSLLNQNISDLNRTSTSVISTSDTSVLGKLPLPNLFPQHIKQEGGFSLEKELGTYGGHTGGGPCDLDGNSGHLIEDTEIWQDLDLPNSLPEISDFELDSEVAHLDNILHDSSGGCGPDGSLLKETKVLVGNGGNCTDVNGTDQQHPLQHHQHQQQQHRHLLQHQQHQLHHQHQQPPSLLSSVMIKEEKDHDNSFIHIRTPGVVKQEKQENGSFCQSQCLQSSMSSLHGGGPMSSTMGAGAVPGYHYKASPSSTVGLQDQKPFGIFSNLPAVAESWTRGGRFGEPSGIQRGNDGLPSAAMSPFSVSFSSSSPRTGENSSSAVPGLSKPSGPTHKICLVCSDEASGCHYGVVTCGSCKVFFKRAVEGWRARQNTDGQHNYLCAGRNDCIIDKIRRKNCPACRFRKCLQAGMNLEARKNKKLIKMKVHRPTGSAEPISNMPVPVIPRMPQLVPTMLSVLKAIEPEIIYSGYDSTLPDTSTRLMTTLNRLGGQQVISAVKWAKSLPGFRNLHLDDQMTLLQCSWLFLMSFSLGWRSYEQCNGNMLCFAPDLVINKERMKLPFMTDQCEQMLKICNEFVRLQVSYDEYLCMKVLLLLSTVPKDGLKSQAVFDEIRMTYIKELGKAIVKREENASQNWQRFYQLTKLLDSMQEMVEGLLQICFYTFVNKTLSVEFPEMLAEIITNQIPKFKDGSVKPLLFHQK | cellular response to glucocorticoid stimulus cellular response to steroid hormone stimulus chromatin organization positive regulation of transcription by RNA polymerase II centrosome; cytoplasm; mitochondrion; nuclear speck; nucleus; spindle DNA-binding transcription factor activity nuclear glucocorticoid receptor activity nuclear receptor activity sequence-specific DNA binding steroid binding steroid hormone binding zinc ion binding Paralichthys olivaceus Chromatin regulator Cytoplasm Cytoskeleton DNA-binding Lipid-binding Metal-binding Mitochondrion Nucleus Receptor Steroid-binding Transcription Transcription regulation Zinc Zinc-finger MDQGGLKRNC MDQGGLKRNCNRDDSLTFGETAVGVGSDTGDTAGSLLQPAAMHLPSPSSLPQLTVAPNGGAGTKDQGEFGGLFESPRGQCEGSEMKEGKIIRLQKRKHHLDIGMFNMEDNLSLLNQNISDLNRTSTSVISTSDTSVLGKLPLPNLFPQHIKQEGGFSLEKELGTYGGHTGGGPCDLDGNSGHLIEDTEIWQDLDLPNSLPEISDFELDSEVAHLDNILHDSSGGCGPDGSLLKETKVLVGNGGNCTDVNGTDQQHPLQHHQHQQQQHRHLLQHQQHQLHHQHQQPPSLLSSVMIKEEKDHDNSFIHIRTPGVVKQEKQENGSFCQSQCLQSSMSSLHGGGPMSSTMGAGAVPGYHYKASPSSTVGLQDQKPFGIFSNLPAVAESWTRGGRFGEPSGIQRGNDGLPSAAMSPFSVSFSSSSPRTGENSSSAVPGLSKPSGPTHKICLVCSDEASGCHYGVVTCGSCKVFFKRAVEGWRARQNTDGQHNYLCAGRNDCIIDKIRRKNCPACRFRKCLQAGMNLEARKNKKLIKMKVHRPTGSAEPISNMPVPVIPRMPQLVPTMLSVLKAIEPEIIYSGYDSTLPDTSTRLMTTLNRLGGQQVISAVKWAKSLPGFRNLHLDDQMTLLQCSWLFLMSFSLGWRSYEQCNGNMLCFAPDLVINKERMKLPFMTDQCEQMLKICNEFVRLQVSYDEYLCMKVLLLLSTVPKDGLKSQAVFDEIRMTYIKELGKAIVKREENASQNWQRFYQLTKLLDSMQEMVEGLLQICFYTFVNKTLSVEFPEMLAEIITNQIPKFKDGSVKPLLFHQK |
dorsal/ventral neural tube patterning neural crest cell differentiation neural crest cell fate commitment neural crest formation neural plate development neurogenesis positive regulation of DNA-templated transcription positive regulation of protein import into nucleus positive regulation of transcription by RNA polymerase II positive regulation of Wnt signaling pathway Wnt signaling pathway | cytoplasm; nucleus | DNA binding DNA-binding transcription factor activity metal ion binding | Xenopus laevis | Activator Cytoplasm Developmental protein Differentiation DNA-binding Metal-binding Neurogenesis Nucleus Reference proteome Repeat Transcription Transcription regulation Wnt signaling pathway Zinc Zinc-finger | MLLDAGAQYP | MLLDAGAQYPAIGVTTFGSSRHHSAGDVTDREVALGINPFADGMGAFKLNPSSHDLASGQTAFTSQAPGYAAAALGHHHHPGHVSSYSSAAFNSTRDFLFRNRGFGEAASAQHSLFASAAGGFPGPHGPHADTTGHLIFPGLHEQAASHASPNVVNGQMRLGFSGDMYGRPDQYGQVTSPRSEHYASSQLHGYGPMNMNMAAHHGAGAFFRYMRQPIKQELICKWIEPEQLANPKKSCNKTFSTMHELVTHVTVEHVGGPEQSNHICVWEECPREGKPFKAKYKLINHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSYTHPSSLRKHMKVHEASSQGSQPSPAASSGYESSTPPTIVSPSAENQSTSSLSPSSSAVHHTSNHSTLSSNFNEWYV | dorsal/ventral neural tube patterning neural crest cell differentiation neural crest cell fate commitment neural crest formation neural plate development neurogenesis positive regulation of DNA-templated transcription positive regulation of protein import into nucleus positive regulation of transcription by RNA polymerase II positive regulation of Wnt signaling pathway Wnt signaling pathway cytoplasm; nucleus DNA binding DNA-binding transcription factor activity metal ion binding Xenopus laevis Activator Cytoplasm Developmental protein Differentiation DNA-binding Metal-binding Neurogenesis Nucleus Reference proteome Repeat Transcription Transcription regulation Wnt signaling pathway Zinc Zinc-finger MLLDAGAQYP MLLDAGAQYPAIGVTTFGSSRHHSAGDVTDREVALGINPFADGMGAFKLNPSSHDLASGQTAFTSQAPGYAAAALGHHHHPGHVSSYSSAAFNSTRDFLFRNRGFGEAASAQHSLFASAAGGFPGPHGPHADTTGHLIFPGLHEQAASHASPNVVNGQMRLGFSGDMYGRPDQYGQVTSPRSEHYASSQLHGYGPMNMNMAAHHGAGAFFRYMRQPIKQELICKWIEPEQLANPKKSCNKTFSTMHELVTHVTVEHVGGPEQSNHICVWEECPREGKPFKAKYKLINHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSYTHPSSLRKHMKVHEASSQGSQPSPAASSGYESSTPPTIVSPSAENQSTSSLSPSSSAVHHTSNHSTLSSNFNEWYV |
calcium ion transmembrane transport calcium ion transmembrane transport via high voltage-gated calcium channel calcium ion transport into cytosol cardiac conduction regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion | dendrite; L-type voltage-gated calcium channel complex; perikaryon; plasma membrane; postsynaptic density membrane; sarcolemma; T-tubule | calmodulin binding high voltage-gated calcium channel activity voltage-gated calcium channel activity | Gallus gallus | Calcium Calcium channel Calcium transport Calmodulin-binding Cell membrane Cell projection Disulfide bond Glycoprotein Ion channel Ion transport Membrane Phosphoprotein Postsynaptic cell membrane Reference proteome Repeat Synapse Transmembrane Transmembrane helix Transport Voltage-gated channel | ALIVVGSIVD | ALIVVGSIVDIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPDKKCDPDSEPANSTEADHSCGSSFAVFYFISFYMLCAFLIIDLFVAVI | calcium ion transmembrane transport calcium ion transmembrane transport via high voltage-gated calcium channel calcium ion transport into cytosol cardiac conduction regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion dendrite; L-type voltage-gated calcium channel complex; perikaryon; plasma membrane; postsynaptic density membrane; sarcolemma; T-tubule calmodulin binding high voltage-gated calcium channel activity voltage-gated calcium channel activity Gallus gallus Calcium Calcium channel Calcium transport Calmodulin-binding Cell membrane Cell projection Disulfide bond Glycoprotein Ion channel Ion transport Membrane Phosphoprotein Postsynaptic cell membrane Reference proteome Repeat Synapse Transmembrane Transmembrane helix Transport Voltage-gated channel ALIVVGSIVD ALIVVGSIVDIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPDKKCDPDSEPANSTEADHSCGSSFAVFYFISFYMLCAFLIIDLFVAVI |
determination of dorsal identity nervous system development neural crest cell development neural crest formation pronephric duct development sequestering of BMP in extracellular matrix somite rostral/caudal axis specification | extracellular space | BMP binding cytokine activity morphogen activity | Xenopus laevis | Cytokine Disulfide bond Glycoprotein Reference proteome Secreted Signal | MNCLVYALGS | MNCLVYALGSLFLLSGLLLPSSEGKKKVSGSQGAIPPPDKGQPNDSEQGQAQPGDRVRGKGKGQALAAEEVLESSQEALHVTERKYLKRDWCKTQPLKQTIHEDGCNSRTIINRFCYGQCNSFYIPRHIRREEGSFQSCSFCKPKKFTTMVVTLNCPELQPPTKKKRITRVKQCRCISIDLD | determination of dorsal identity nervous system development neural crest cell development neural crest formation pronephric duct development sequestering of BMP in extracellular matrix somite rostral/caudal axis specification extracellular space BMP binding cytokine activity morphogen activity Xenopus laevis Cytokine Disulfide bond Glycoprotein Reference proteome Secreted Signal MNCLVYALGS MNCLVYALGSLFLLSGLLLPSSEGKKKVSGSQGAIPPPDKGQPNDSEQGQAQPGDRVRGKGKGQALAAEEVLESSQEALHVTERKYLKRDWCKTQPLKQTIHEDGCNSRTIINRFCYGQCNSFYIPRHIRREEGSFQSCSFCKPKKFTTMVVTLNCPELQPPTKKKRITRVKQCRCISIDLD |
chromatin organization chromosome condensation nucleate erythrocyte maturation | chromatin; extracellular space; nucleoplasm | chromatin DNA binding serine-type endopeptidase inhibitor activity | Gallus gallus | 3D-structure Chromatin regulator Chromosome Direct protein sequencing DNA condensation DNA-binding Nucleus Protease inhibitor Reference proteome | MEQVSASIGN | MEQVSASIGNFTVDLFNKLNETNRDKNIFFSPWSISSALALTYLAAKGSTAREMAEVLHFTEAVRAESSSVARPSRGRPKRRRMDPEHEQAENIHSGFKELLTAFNKPRNNYSLRSANRIYVEKTYALLPTYLQLSKKYYKAEPQKVNFKTAPEQSRKEINTWVEKQTESKIKNLLSSDDVKATTRLILVNAIYFKAEWEVKFQAEKTSIQPFRLSKNKSKPVKMMYMRDTFPVLIMEKMNFKMIELPYVKRELSMFILLPDDIKDGTTGLEQLERELTYERLSEWADSKMMTETLVDLHLPKFSLEDRIDLRDTLRNMGMTTAFTTNADFRGMTDKKDLAISKVIHQSFVAVDEKGTEAAAATAVIISFTTSVINHVLKFKVDHPFHFFIRHNKSKTILFFGRFCCPVE | chromatin organization chromosome condensation nucleate erythrocyte maturation chromatin; extracellular space; nucleoplasm chromatin DNA binding serine-type endopeptidase inhibitor activity Gallus gallus 3D-structure Chromatin regulator Chromosome Direct protein sequencing DNA condensation DNA-binding Nucleus Protease inhibitor Reference proteome MEQVSASIGN MEQVSASIGNFTVDLFNKLNETNRDKNIFFSPWSISSALALTYLAAKGSTAREMAEVLHFTEAVRAESSSVARPSRGRPKRRRMDPEHEQAENIHSGFKELLTAFNKPRNNYSLRSANRIYVEKTYALLPTYLQLSKKYYKAEPQKVNFKTAPEQSRKEINTWVEKQTESKIKNLLSSDDVKATTRLILVNAIYFKAEWEVKFQAEKTSIQPFRLSKNKSKPVKMMYMRDTFPVLIMEKMNFKMIELPYVKRELSMFILLPDDIKDGTTGLEQLERELTYERLSEWADSKMMTETLVDLHLPKFSLEDRIDLRDTLRNMGMTTAFTTNADFRGMTDKKDLAISKVIHQSFVAVDEKGTEAAAATAVIISFTTSVINHVLKFKVDHPFHFFIRHNKSKTILFFGRFCCPVE |
angiogenesis blood vessel development endothelial cell-cell adhesion heart development phosphorylation positive regulation of angiogenesis transmembrane receptor protein tyrosine kinase signaling pathway vasculature development | plasma membrane; receptor complex | ATP binding transmembrane receptor protein tyrosine kinase activity | Danio rerio | Angiogenesis ATP-binding Cell membrane Kinase Membrane Nucleotide-binding Phosphoprotein Receptor Reference proteome Transferase Transmembrane Tyrosine-protein kinase | QLLQFAADVA | QLLQFAADVATGMHYLSDKQFIHRDLAARNVLVGDNLVAKIADFGLSRGEEVYVKKTMGRLPVRWMAIESLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFSQISVQLNRMQEARKAYVNMALFENFTYAGIDATAEEA | angiogenesis blood vessel development endothelial cell-cell adhesion heart development phosphorylation positive regulation of angiogenesis transmembrane receptor protein tyrosine kinase signaling pathway vasculature development plasma membrane; receptor complex ATP binding transmembrane receptor protein tyrosine kinase activity Danio rerio Angiogenesis ATP-binding Cell membrane Kinase Membrane Nucleotide-binding Phosphoprotein Receptor Reference proteome Transferase Transmembrane Tyrosine-protein kinase QLLQFAADVA QLLQFAADVATGMHYLSDKQFIHRDLAARNVLVGDNLVAKIADFGLSRGEEVYVKKTMGRLPVRWMAIESLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFSQISVQLNRMQEARKAYVNMALFENFTYAGIDATAEEA |
neuron cellular homeostasis removal of superoxide radicals response to metal ion response to methylmercury response to xenobiotic stimulus | cytosol; mitochondrion; nucleus; peroxisome | copper ion binding superoxide dismutase activity | Danio rerio | Antioxidant Copper Cytoplasm Disulfide bond Lipoprotein Metal-binding Nucleus Oxidoreductase Palmitate Reference proteome Zinc | MVNKAVCVLK | MVNKAVCVLKGTGEVTGTVYFNQEGEKKPVKVTGEITGLTPGKHGFHVHAFGDNTNGCISAGPHFNPHDKTHGGPTDSVRHVGDLGNVTADASGVAKIEIEDAMLTLSGQHSIIGRTMVIHEKEDDLGKGGNEESLKTGNAGGRLACGVIGITQ | neuron cellular homeostasis removal of superoxide radicals response to metal ion response to methylmercury response to xenobiotic stimulus cytosol; mitochondrion; nucleus; peroxisome copper ion binding superoxide dismutase activity Danio rerio Antioxidant Copper Cytoplasm Disulfide bond Lipoprotein Metal-binding Nucleus Oxidoreductase Palmitate Reference proteome Zinc MVNKAVCVLK MVNKAVCVLKGTGEVTGTVYFNQEGEKKPVKVTGEITGLTPGKHGFHVHAFGDNTNGCISAGPHFNPHDKTHGGPTDSVRHVGDLGNVTADASGVAKIEIEDAMLTLSGQHSIIGRTMVIHEKEDDLGKGGNEESLKTGNAGGRLACGVIGITQ |
angioblast cell migration involved in selective angioblast sprouting anterior/posterior pattern specification axon guidance axon target recognition blood vessel development blood vessel morphogenesis cell adhesion cell migration involved in sprouting angiogenesis ephrin receptor signaling pathway optic vesicle morphogenesis regulation of chemotaxis rhombomere boundary formation somitogenesis synaptic target recognition | plasma membrane | ephrin receptor binding | Danio rerio | Angiogenesis Cell membrane Developmental protein Differentiation Disulfide bond Glycoprotein Membrane Neurogenesis Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix | MGDSLWRYYF | MGDSLWRYYFGVLVIACKVNLSRALILDSIYWNTTNTKFVPGQGLVLYPQIGDKMDIVCPRVEGGSMEGVEYYKLYMVPLEQLKSCQVTKADTPLLNCVKPDQDVKFTLKFQEFSPNLWGLEFFRGKDYYIISTSNGTMEGLDNQEGGVCKTKSMKIIMKVGQNPSDPISPKDYPTSYPPKHPDLGGKDSKSNEVLKPDASPHGEDKGDGNKSSSVIGSEVALFACIASASVIVIIIIIMLVFLLLKYRRRHRKHSPQHATTLSLSTLATPKRGGSGGNNNGSEPSDIIIPLRTADSVFCPHYEKVSGDYGHPVYIVQEMPPQSPANIYYKV | angioblast cell migration involved in selective angioblast sprouting anterior/posterior pattern specification axon guidance axon target recognition blood vessel development blood vessel morphogenesis cell adhesion cell migration involved in sprouting angiogenesis ephrin receptor signaling pathway optic vesicle morphogenesis regulation of chemotaxis rhombomere boundary formation somitogenesis synaptic target recognition plasma membrane ephrin receptor binding Danio rerio Angiogenesis Cell membrane Developmental protein Differentiation Disulfide bond Glycoprotein Membrane Neurogenesis Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix MGDSLWRYYF MGDSLWRYYFGVLVIACKVNLSRALILDSIYWNTTNTKFVPGQGLVLYPQIGDKMDIVCPRVEGGSMEGVEYYKLYMVPLEQLKSCQVTKADTPLLNCVKPDQDVKFTLKFQEFSPNLWGLEFFRGKDYYIISTSNGTMEGLDNQEGGVCKTKSMKIIMKVGQNPSDPISPKDYPTSYPPKHPDLGGKDSKSNEVLKPDASPHGEDKGDGNKSSSVIGSEVALFACIASASVIVIIIIIMLVFLLLKYRRRHRKHSPQHATTLSLSTLATPKRGGSGGNNNGSEPSDIIIPLRTADSVFCPHYEKVSGDYGHPVYIVQEMPPQSPANIYYKV |
angioblast cell migration involved in selective angioblast sprouting angiogenesis blood vessel development convergent extension ephrin receptor signaling pathway lymph vessel development phosphorylation venous blood vessel morphogenesis | plasma membrane; receptor complex | ATP binding ephrin receptor activity transmembrane receptor protein tyrosine kinase activity | Danio rerio | ATP-binding Cell membrane Disulfide bond Kinase Membrane Nucleotide-binding Receptor Reference proteome Repeat Signal Transferase Transmembrane Transmembrane helix Tyrosine-protein kinase | MELFSRNVAA | MELFSRNVAAFWIILLEFLLGSVAEEEVLMNTKTETSDLKWTTHSRSKPEWEEVSGLDEENNSVRTYQICQADGSSSHWLRSKLIERRGASQVYVELFFTMVECSSRNTHHRSCKETFNLYYYQSDTDDATATHPAWMENPYTKVDTVAADFLLRKGGEKKVNVKTLRLGPLSKRGFYLAFQAQGACMALLSVRVFFKKCPALTRSLSVFPETVPRSLVQEAVGQCVANAAQPGPSPRPPKMFCGEDGQWVDQPTTTCTCLPGFEASHGELECRACPVGLFKMGSGTGPCSVCPENSQTGETGSAACVCRSGFYRALSDSADTPCTRPPSSPRSPVPQVNDTSLTLEWSEPLDSGGRSDLSYSVECRMCSTPGSPCTLCSDGVNYRPSQTGIQGRRVSIWGLRPHTTYSFTVMALNGVSAQSQQGPAGETINITTSPNVPVLVSGLRKSTATESSLTLYWNTPTQSHYRILQYQIRYCEKERGSEENSCHYMESNNNEVVLSDLRRATQYEVQVRARTFAGYGSFGKAILFRTLPDEDDSSSPLLVTGILIAMGMLLLIIVIGAAIYCIRKQNNYKDPELSDKNGQYLMGQGVKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLRIPGKKENYVAIKTLKGGYTDKQRRDFLAEASIMGQFQHPNIIHLEGIITASCPVMILTEFMENGALDSFLRLNDGQFTPIQLVGMLRGIASGMKYLSEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLQENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTCASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPDCPTYLHQLMLDCWQKERTARPRFANIVSALDKLIRNPASLKITAQEGAGPSHPLLDQRSPLTPSSCGTVGDWLRAIKMERYEETFLQAGYTSMQLVTHINTEDLLRLGITLAGHQKKILSSIEALGIQNKAPGNVLY | angioblast cell migration involved in selective angioblast sprouting angiogenesis blood vessel development convergent extension ephrin receptor signaling pathway lymph vessel development phosphorylation venous blood vessel morphogenesis plasma membrane; receptor complex ATP binding ephrin receptor activity transmembrane receptor protein tyrosine kinase activity Danio rerio ATP-binding Cell membrane Disulfide bond Kinase Membrane Nucleotide-binding Receptor Reference proteome Repeat Signal Transferase Transmembrane Transmembrane helix Tyrosine-protein kinase MELFSRNVAA MELFSRNVAAFWIILLEFLLGSVAEEEVLMNTKTETSDLKWTTHSRSKPEWEEVSGLDEENNSVRTYQICQADGSSSHWLRSKLIERRGASQVYVELFFTMVECSSRNTHHRSCKETFNLYYYQSDTDDATATHPAWMENPYTKVDTVAADFLLRKGGEKKVNVKTLRLGPLSKRGFYLAFQAQGACMALLSVRVFFKKCPALTRSLSVFPETVPRSLVQEAVGQCVANAAQPGPSPRPPKMFCGEDGQWVDQPTTTCTCLPGFEASHGELECRACPVGLFKMGSGTGPCSVCPENSQTGETGSAACVCRSGFYRALSDSADTPCTRPPSSPRSPVPQVNDTSLTLEWSEPLDSGGRSDLSYSVECRMCSTPGSPCTLCSDGVNYRPSQTGIQGRRVSIWGLRPHTTYSFTVMALNGVSAQSQQGPAGETINITTSPNVPVLVSGLRKSTATESSLTLYWNTPTQSHYRILQYQIRYCEKERGSEENSCHYMESNNNEVVLSDLRRATQYEVQVRARTFAGYGSFGKAILFRTLPDEDDSSSPLLVTGILIAMGMLLLIIVIGAAIYCIRKQNNYKDPELSDKNGQYLMGQGVKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLRIPGKKENYVAIKTLKGGYTDKQRRDFLAEASIMGQFQHPNIIHLEGIITASCPVMILTEFMENGALDSFLRLNDGQFTPIQLVGMLRGIASGMKYLSEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLQENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTCASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPDCPTYLHQLMLDCWQKERTARPRFANIVSALDKLIRNPASLKITAQEGAGPSHPLLDQRSPLTPSSCGTVGDWLRAIKMERYEETFLQAGYTSMQLVTHINTEDLLRLGITLAGHQKKILSSIEALGIQNKAPGNVLY |
angiogenesis ephrin receptor signaling pathway Kupffer's vesicle development phosphorylation somitogenesis | plasma membrane; receptor complex | ATP binding ephrin receptor activity transmembrane receptor protein tyrosine kinase activity | Danio rerio | ATP-binding Cell membrane Disulfide bond Kinase Membrane Nucleotide-binding Receptor Reference proteome Repeat Signal Transferase Transmembrane Transmembrane helix Tyrosine-protein kinase | MDRVCWIMAL | MDRVCWIMALSWFWMVSTGLVSAEEEVLMNTKLETSDLRWTIYPSGDPEWEEMSGLDEEGNSVRTFQVCPMDSSVSHWLRTRFIPRHGASQVYVEIRFTMMECSAMPASFRTCKETFNLYYYQSDEDTASATHPAWMENPYSKVDTVAADFLLRRGGERKSNVKTVRVGPLSKKGFYLAFQTQGACMALLSVRVFFKKCPAVSRAFSSFPETLPHSLVQQAEGVCVDNSAPTGQSTAPPTMFCGEDGQWVGPPSSTCACKPGYEPVDSDRCRACGLGQYKASVGGSLCRVCPDNSNTHFAGSSLCVCRPGYHRATSDLPDSACTKPPSAPRSIIYQINDTVVTLEWSEPLDRGGRSDLSYSVECMHCRGSLCVQCADSITYRPGQMGVPGRRVIIRGLLPHTTYTFTVLAQNGVSAVSHTSPASSSVNITTSRDVAVPVSGIRRIKASESSVSISWTVPPQTQHSIQDYQLRYSLKGQDDGWQYVSSRSSSVVLNDLSRASQYQVQVRARTAAGYGHFSSAVSISTLPDDEESPSRLMLTGVLVAIGLLILIAVVIVAVFCFRRSTRRRDPDPDKSGQFLMGQGIKVYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVCRGRLKVPGKKENYVAIKTLKGGYTDKQRRDFLSEASIMGQFQHPNIIHLEGVITASCPVMILTEYMENGALDSFLRLNDGQFTPIQLVGMLRGIASGMKYLSEMSFVHRDLAARNILVNSNLVCKVSDFGLSRFLTENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPECPASLHQLMLDCWQKERSSRPRFCAIVSALDRLIRNPASLKITGRIPDGPSHPLLDQRAPPPLSHCSSVADWLRAIKMERYEDAFMQAGFTAIQHITHISTEDLLRIGVTLAGHQKKILSSVQTLRIHGGSLRY | angiogenesis ephrin receptor signaling pathway Kupffer's vesicle development phosphorylation somitogenesis plasma membrane; receptor complex ATP binding ephrin receptor activity transmembrane receptor protein tyrosine kinase activity Danio rerio ATP-binding Cell membrane Disulfide bond Kinase Membrane Nucleotide-binding Receptor Reference proteome Repeat Signal Transferase Transmembrane Transmembrane helix Tyrosine-protein kinase MDRVCWIMAL MDRVCWIMALSWFWMVSTGLVSAEEEVLMNTKLETSDLRWTIYPSGDPEWEEMSGLDEEGNSVRTFQVCPMDSSVSHWLRTRFIPRHGASQVYVEIRFTMMECSAMPASFRTCKETFNLYYYQSDEDTASATHPAWMENPYSKVDTVAADFLLRRGGERKSNVKTVRVGPLSKKGFYLAFQTQGACMALLSVRVFFKKCPAVSRAFSSFPETLPHSLVQQAEGVCVDNSAPTGQSTAPPTMFCGEDGQWVGPPSSTCACKPGYEPVDSDRCRACGLGQYKASVGGSLCRVCPDNSNTHFAGSSLCVCRPGYHRATSDLPDSACTKPPSAPRSIIYQINDTVVTLEWSEPLDRGGRSDLSYSVECMHCRGSLCVQCADSITYRPGQMGVPGRRVIIRGLLPHTTYTFTVLAQNGVSAVSHTSPASSSVNITTSRDVAVPVSGIRRIKASESSVSISWTVPPQTQHSIQDYQLRYSLKGQDDGWQYVSSRSSSVVLNDLSRASQYQVQVRARTAAGYGHFSSAVSISTLPDDEESPSRLMLTGVLVAIGLLILIAVVIVAVFCFRRSTRRRDPDPDKSGQFLMGQGIKVYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVCRGRLKVPGKKENYVAIKTLKGGYTDKQRRDFLSEASIMGQFQHPNIIHLEGVITASCPVMILTEYMENGALDSFLRLNDGQFTPIQLVGMLRGIASGMKYLSEMSFVHRDLAARNILVNSNLVCKVSDFGLSRFLTENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPECPASLHQLMLDCWQKERSSRPRFCAIVSALDRLIRNPASLKITGRIPDGPSHPLLDQRAPPPLSHCSSVADWLRAIKMERYEDAFMQAGFTAIQHITHISTEDLLRIGVTLAGHQKKILSSVQTLRIHGGSLRY |
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