Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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chaperone cofactor-dependent protein refolding chaperone-mediated autophagy translocation complex disassembly clathrin coat disassembly embryo development ending in birth or egg hatching embryonic organ development gastrulation late endosomal microautophagy protein refolding protein targeting to lysosome involved in ch... | autophagosome; cytoplasm; dendrite; lysosomal membrane; lysosome; nucleolus; nucleus; plasma membrane; postsynaptic cytosol; presynaptic cytosol; ribonucleoprotein complex; terminal bouton | ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone clathrin-uncoating ATPase activity heat shock protein binding phosphoprotein binding protein folding chaperone protein-macromolecule adaptor activity | Gallus gallus | ATP-binding Autophagy Cell membrane Chaperone Cytoplasm Lysosome Membrane Nucleotide-binding Nucleus Reference proteome Stress response | MSKGPAVGID | MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDSVVQSDMKHWPFTVVNDAGRPKVQVEYKGETKSFYPEEISSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQGTKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGAERNLLIFDLGGGTFDVSILTIENGIFEVKSTAGDTHLGGEDFDNRLVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEKLNADLFRGTLDPVEKA... | chaperone cofactor-dependent protein refolding chaperone-mediated autophagy translocation complex disassembly clathrin coat disassembly embryo development ending in birth or egg hatching embryonic organ development gastrulation late endosomal microautophagy protein refolding protein targeting to lysosome involved in ch... |
prostaglandin biosynthetic process prostaglandin metabolic process | cytoplasm | calcium ion binding glutathione transferase activity magnesium ion binding prostaglandin-D synthase activity | Gallus gallus | Cytoplasm Fatty acid biosynthesis Fatty acid metabolism Isomerase Lipid biosynthesis Lipid metabolism Prostaglandin biosynthesis Prostaglandin metabolism Reference proteome Transferase | MPNYKLTYFN | MPNYKLTYFNLRGRAEICRYLFAYAGIKYEDHRLEGADWPKIKPTIPFGKVPILEVDGVIIHQSLAIARYLARESGLAGQTPVEQALADAIVDTIDDFMMLFPWAEKNQDVKEKAFNDILTNKAPELLKDLDTFLGDKKWFVGKSVTWADFYWDVCSTTLLSYKADLADKYPRLLALRDRVEALPAIAAWIQKRPKTAI | prostaglandin biosynthetic process prostaglandin metabolic process cytoplasm calcium ion binding glutathione transferase activity magnesium ion binding prostaglandin-D synthase activity Gallus gallus Cytoplasm Fatty acid biosynthesis Fatty acid metabolism Isomerase Lipid biosynthesis Lipid metabolism Prostaglandin bios... |
apoptotic process involved in development cell proliferation in forebrain epithelial cell maturation eye development forebrain dorsal/ventral pattern formation lens development in camera-type eye lens fiber cell apoptotic process lens fiber cell differentiation negative regulation of DNA-templated transcription negativ... | nucleus; transcription regulator complex | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding transcription corepressor binding | Oryzias latipes | Developmental protein DNA-binding Homeobox Nucleus Reference proteome Repressor Transcription Transcription regulation | MVFRAPLDFI | MVFRAPLDFISASRLLLPHFADAPPVLSRSRSPEHPPAGFLSLALPGLCFSATQIASVCETLEETGDIERLARFLWSLPVNTDGRDSISEHESVQRARAVVAFHTGCYRELYRILETHRFTRASHSKLQAMWLEAHYREAEKLRGRPLGPVDKYRVRKKFPLPRTIWDGEQKTHCFKERTRGLLREWYLQDPYPNPGKKRELAHATGLTPTQVGNWFKNRRQRDRAAAAKNRLQHHRICPDSACTLSGGDSSERADGDTFLSVTDSDSDLDV | apoptotic process involved in development cell proliferation in forebrain epithelial cell maturation eye development forebrain dorsal/ventral pattern formation lens development in camera-type eye lens fiber cell apoptotic process lens fiber cell differentiation negative regulation of DNA-templated transcription negativ... |
inner ear development intestinal absorption membrane repolarization regulation of gastric acid secretion renal absorption | basolateral plasma membrane; cytoplasm; cytoplasmic vesicle membrane; endoplasmic reticulum; membrane raft; monoatomic ion channel complex; plasma membrane; voltage-gated potassium channel complex | calmodulin binding delayed rectifier potassium channel activity outward rectifier potassium channel activity phosphatidylinositol-4,5-bisphosphate binding voltage-gated potassium channel activity | Squalus acanthias | Calmodulin-binding Cell membrane Coiled coil Cytoplasmic vesicle Endoplasmic reticulum Ion channel Ion transport Membrane Potassium Potassium channel Potassium transport Transmembrane Transmembrane helix Transport Voltage-gated channel | MSSEVKSRWS | MSSEVKSRWSGSGSQKSGTARKPTMLEMAENAASRHYEPVPLPLQRSNSPDSSTDKNPESRAADSRAEVIINPDIPPKAIALPLSRYRGRNPFFSKVNIQGRTYNFLERPTGWKCFIYHFTVFLIVLVCLIFSVMSTIEQYHYFANRALVWMEIVLVVFFGTEYIVRLWSAGCRSKYVGFWGRLRFARKPISIIDLIVVVASVIVLCVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVDDSGSQQFGSYADALWWGVVTVTTIGYGDKVPQTWIGRT... | inner ear development intestinal absorption membrane repolarization regulation of gastric acid secretion renal absorption basolateral plasma membrane; cytoplasm; cytoplasmic vesicle membrane; endoplasmic reticulum; membrane raft; monoatomic ion channel complex; plasma membrane; voltage-gated potassium channel complex c... |
mRNA transport regulation of translation | endoplasmic reticulum; nucleus; ribonucleoprotein complex | DNA binding mRNA 3'-UTR binding | Xenopus laevis | Cytoplasm Developmental protein Direct protein sequencing DNA-binding Endoplasmic reticulum mRNA transport Nucleus Reference proteome Repeat RNA-binding Transcription Transcription regulation Translation regulation Transport | MNKLYIGNLS | MNKLYIGNLSENVSPTDLESLFKESKIPFTGQFLVKSGYAFVDCPDETWAMKAIDTLSGKVELHGKVIEVEHSVPKRQRSRKLQIRNIPPHLQWEVLDSLLAQYGTVENCEQVNTESETAVVNVTYANKEHARQGLEKLNGYQLENYSLKVTYIPDEMATPQAPSQQLQQQPQQQHPQGRRGFGQRGPARQGSPGAAARPKPQTEVPLRMLVPTQFVGAIIGKEGATIRNITKQTQSKIDIHRKENAGAAEKPITIHSTPEGCSAACKIIMEIMQKEAQDTKFTEEIPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKI... | mRNA transport regulation of translation endoplasmic reticulum; nucleus; ribonucleoprotein complex DNA binding mRNA 3'-UTR binding Xenopus laevis Cytoplasm Developmental protein Direct protein sequencing DNA-binding Endoplasmic reticulum mRNA transport Nucleus Reference proteome Repeat RNA-binding Transcription Transcr... |
DNA replication initiation double-strand break repair via break-induced replication mitotic DNA replication initiation mitotic DNA replication preinitiation complex assembly mitotic intra-S DNA damage checkpoint signaling | chromatin; cytosol; DNA replication preinitiation complex; nuclear replication fork; nucleus | chromatin binding DNA replication origin binding single-stranded DNA binding | Schizosaccharomyces pombe | Cell cycle DNA replication Nucleus Reference proteome | MFIKRSDYAS | MFIKRSDYASAYLKIKEASVSGGCTVQLFVALDPDALCACKLLSTLLKGDFISHKIRPVSGYRDLEQANKTLLEQNEDIKFIILLNCGTMVDLNNYLVSMEDVSIYVIDSHRPHNLNNIYIENNIFVFDDGDIEEDMNKIHDAWYAFNSHELSDEENSDSSNEREEEVEDDNRSVESYSSSDYQARSRRRFSEETTQRRAEIKEKRKKRKEFASILSEYYEKGSWYGESITNILFAVASMLGREDNDMLWLAIVGLTCLEIHCQSSKKYFNRSYSLLKDEVNRLNPSPLENQIVGRAHGKTPHDQSIRLEDEFRFMLVRH... | DNA replication initiation double-strand break repair via break-induced replication mitotic DNA replication initiation mitotic DNA replication preinitiation complex assembly mitotic intra-S DNA damage checkpoint signaling chromatin; cytosol; DNA replication preinitiation complex; nuclear replication fork; nucleus chrom... |
endocytosis negative regulation of establishment of bipolar cell polarity negative regulation of protein localization to cell tip phosphorylation regulation of endocytosis signal transduction | cell division site; cell periphery; cell tip; cytoplasm; nucleus | ATP binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity | Schizosaccharomyces pombe | ATP-binding Cytoplasm Kinase Nucleotide-binding Reference proteome Serine/threonine-protein kinase Transferase | MSTTSSHSNV | MSTTSSHSNVVGVHYRVGKKIGEGSFGMLFQGVNLINNQPIALKFESRKSEVPQLRDEYLTYKLLMGLPGIPSVYYYGQEGMYNLLVMDLLGPSLEDLFDYCGRRFSPKTVAMIAKQMITRIQSVHERHFIYRDIKPDNFLIGFPGSKTENVIYAVDFGMAKQYRDPKTHVHRPYNEHKSLSGTARYMSINTHLGREQSRRDDLESMGHVFMYFLRGSLPWQGLKAATNKQKYEKIGEKKQVTPLKELCEGYPKEFLQYMIYARNLGYEEAPDYDYLRSLFDSLLLRINETDDGKYDWTLLNNGKGWQYSAAKQHVVQRR... | endocytosis negative regulation of establishment of bipolar cell polarity negative regulation of protein localization to cell tip phosphorylation regulation of endocytosis signal transduction cell division site; cell periphery; cell tip; cytoplasm; nucleus ATP binding protein kinase activity protein serine kinase activ... |
biological process involved in interaction with host cell-substrate adhesion cellular response to starvation filamentous growth filamentous growth of a population of unicellular organisms in response to starvation fungal-type cell wall organization negative regulation of proteolysis protein O-linked glycosylation prote... | endoplasmic reticulum; endoplasmic reticulum membrane; plasma membrane | dolichyl-phosphate-mannose-protein mannosyltransferase activity mannosyltransferase activity | Candida albicans | Endoplasmic reticulum Glycoprotein Glycosyltransferase Membrane Reference proteome Repeat Transferase Transmembrane Transmembrane helix | MAKKPVTPAS | MAKKPVTPASKVAAKQAAVRSRHQEDVFTLDPLIDPIFQKGELRSYLVTEPSPSVLKKRSIHTKEYWMLSSLLLIAFYVRMYNLSNPNSVVFDEVHFGGFARKYILGTFFMDVHPPLAKMLFGAVGAIGGFKGDFEFKSIGDKFPDSTPYIFMRQFPALLGVGTVILCYLTLRQSGVRPIIAYITTFLLIIENSNVTISRYILLDSPLIFFIAAAIYAWKKFEIQIPFTFGWYRSLLATGIALGLALSSKWVGLFTVAWVGFLCIYQLWFLIGDLSVSTKKIWGHFFARGIILLGVPIALYLGFFAIHFQLLNKEGDGGA... | biological process involved in interaction with host cell-substrate adhesion cellular response to starvation filamentous growth filamentous growth of a population of unicellular organisms in response to starvation fungal-type cell wall organization negative regulation of proteolysis protein O-linked glycosylation prote... |
ergosterol biosynthetic process methylation zymosterol biosynthetic process | endoplasmic reticulum; plasma membrane | sterol 24-C-methyltransferase activity | Candida albicans | Lipid biosynthesis Lipid metabolism Methyltransferase Reference proteome S-adenosyl-L-methionine Steroid biosynthesis Steroid metabolism Sterol biosynthesis Sterol metabolism Transferase | MSPVQLAEKN | MSPVQLAEKNYERDEQFTKALHGESYKKTGLSALIAKSKDAASVAAEGYFKHWDGGISKDDEEKRLNDYSQLTHHYYNLVTDFYEYGWGSSFHFSRYYKGEAFRQATARHEHFLAHKMNLNENMKVLDVGCGVGGPGREITRFTDCEIVGLNNNDYQIERANHYAKKYHLDHKLSYVKGDFMQMDFEPESFDAVYAIEATVHAPVLEGVYSEIYKVLKPGGVFGVYEWVMTDKYDETNEEHRKIAYGIEVGDGIPKMYSRKVAEQALKNVGFEIEYQKDLADVDDEIPWYYPLSGDLKFCQTFGDYLTVFRTSRIGRFIT... | ergosterol biosynthetic process methylation zymosterol biosynthetic process endoplasmic reticulum; plasma membrane sterol 24-C-methyltransferase activity Candida albicans Lipid biosynthesis Lipid metabolism Methyltransferase Reference proteome S-adenosyl-L-methionine Steroid biosynthesis Steroid metabolism Sterol bios... |
cellular response to UV cytoplasm protein quality control by the ubiquitin-proteasome system DNA damage response DNA repair DNA-templated transcription termination double-strand break repair via homologous recombination error-free postreplication DNA repair error-free translesion synthesis error-prone translesion synth... | chromosome, telomeric region; cytoplasm; fungal biofilm matrix; HULC complex; MUB1-RAD6-UBR2 ubiquitin ligase complex; nucleus; Rad6-Rad18 complex; RAD6-UBR2 ubiquitin ligase complex; UBR1-RAD6 ubiquitin ligase complex | ATP binding proteasome binding single-stranded DNA binding single-stranded DNA helicase activity ubiquitin conjugating enzyme activity ubiquitin-protein transferase activity | Candida albicans | ATP-binding Chromatin regulator Cytoplasm DNA damage DNA repair Nucleotide-binding Nucleus Reference proteome Sporulation Transcription Transcription regulation Transferase Ubl conjugation pathway | MSTPARRRLM | MSTPARRRLMRDFKRMQQDPPSGVSASPLPDNVMKWNAVIIGPSDTPFEDGTFRLLLSFDEQYPNKPPQVKFISEMFHPNVYASGELCLDILQNRWSPTYDVSSILTSVQSLLNDPNISSPANVEAANLYKDHRSLYVKRVRETVENSWNDDDDEEEEEEDEDEAEDEDDDDDDNIDED | cellular response to UV cytoplasm protein quality control by the ubiquitin-proteasome system DNA damage response DNA repair DNA-templated transcription termination double-strand break repair via homologous recombination error-free postreplication DNA repair error-free translesion synthesis error-prone translesion synth... |
cell wall organization pectin catabolic process | extracellular region | polygalacturonase activity | Aspergillus aculeatus | 3D-structure Cell wall biogenesis/degradation Cleavage on pair of basic residues Disulfide bond Glycoprotein Glycosidase Hydrolase Repeat Secreted Signal Zymogen | MHLNTTLLVS | MHLNTTLLVSLALGAASVLASPAPPAITAPPTAEEIAKRATTCTFSGSNGASSASKSKTSCSTIVLSNVAVPSGTTLDLTKLNDGTHVIFSGETTFGYKEWSGPLISVSGSDLTITGASGHSINGDGSRWWDGEGGNGGKTKPKFFAAHSLTNSVISGLKIVNSPVQVFSVAGSDYLTLKDITIDNSDGDDNGGHNTDAFDIGTSTYVTISGATVYNQDDCVAVNSGENIYFSGGYCSGGHGLSIGSVGGRSDNTVKNVTFVDSTIINSDNGVRIKTNIDTTGSVSDVTYKDITLTSIAKYGIVVQQNYGDTSSTPTTGV... | cell wall organization pectin catabolic process extracellular region polygalacturonase activity Aspergillus aculeatus3D-structure Cell wall biogenesis/degradation Cleavage on pair of basic residues Disulfide bond Glycoprotein Glycosidase Hydrolase Repeat Secreted Signal Zymogen MHLNTTLLVS MHLNTTLLVSLALGAASVLASPAPPAITAP... |
arabinan catabolic process arabinose metabolic process L-arabinose metabolic process pectin catabolic process xylan catabolic process | extracellular region | alpha-L-arabinofuranosidase activity | Emericella nidulans | Carbohydrate metabolism Disulfide bond Glycoprotein Glycosidase Hydrolase Polysaccharide degradation Reference proteome Secreted Signal Xylan degradation | MTMSRSSRSS | MTMSRSSRSSVLALALATGSLVAAGPCDIYSSGGTPCIAAHSTTRALYSSYNGPLYQVQRASDGTTTTITPLSAGGVADASAQDAFCENTTCLITIIYDQSGNGNDLTQAPPGGFNGPDVGGYDNLAGAIGAPVTLNGKKAYGVFVSPGTGYRNNEAIGTATGDEPEGMYAVLDGTHYNDGCCFDYGNAETSSLDTGNGHMEAIYYGTNTAWGYGAGNGPWIMADLENGLFSGQSSDYNAGDPSISYRFVTAILKGGPNLWALRGGNAASGSLSTYYNGIRPTDASGYNPMSKEGAIILGIGGDNSVSAQGTFYEGAMTD... | arabinan catabolic process arabinose metabolic process L-arabinose metabolic process pectin catabolic process xylan catabolic process extracellular region alpha-L-arabinofuranosidase activity Emericella nidulans Carbohydrate metabolism Disulfide bond Glycoprotein Glycosidase Hydrolase Polysaccharide degradation Refere... |
chromatin remodeling DNA repair-dependent chromatin remodeling regulation of DNA-templated transcription transcription elongation-coupled chromatin remodeling transcription initiation-coupled chromatin remodeling | chromatin; cytosol; HIR complex; nucleus | ATP-dependent H3-H4 histone complex chaperone activity | Schizosaccharomyces pombe | Chromatin regulator Cytoplasm Nucleus Phosphoprotein Reference proteome Repeat Repressor Transcription Transcription regulation WD repeat | MHIFVPKLLE | MHIFVPKLLENHQFSSISSSKDFVAVSAETNVYILSKDFFYPKSSEKRIIQSLNGHKTTHLSFDSPISCIRFTYDGSCLAVATEAGTFLYHSEKWDKAFQVLSGPAYEVCWSQQGHILATSWKQISIYVKDEGLRTETIVKKTEHADSNHQPAVSIEESKEAVESTSQSSEISFKLIKVIEGHHTFVGGLAFDPMGQFLASQSFDHTLKVWKLSTFGVEKSIAKPFEQMPTGNRFLRLSWSPDGAHIASVNAVNEGAYVIAIVQRDTWTYDINLVGHQGPLECATFNPYLYEDPFQKSIIASAAHDGCVSIWNTACARPM... | chromatin remodeling DNA repair-dependent chromatin remodeling regulation of DNA-templated transcription transcription elongation-coupled chromatin remodeling transcription initiation-coupled chromatin remodeling chromatin; cytosol; HIR complex; nucleus ATP-dependent H3-H4 histone complex chaperone activity Schizosacch... |
autophagosome assembly macroautophagy nucleophagy protein localization to phagophore assembly site | autophagosome; cytoplasmic vesicle membrane; endoplasmic reticulum membrane; fungal-type vacuole membrane; Golgi membrane; phagophore assembly site; phagophore assembly site membrane | phospholipid scramblase activity | Schizosaccharomyces pombe | 3D-structure Autophagy Cytoplasmic vesicle Endoplasmic reticulum Golgi apparatus Lipid transport Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport | MFYQPAQNKK | MFYQPAQNKKQYDDLADIEAQNNVPNTQEVLEAWQESLDSDEDESSPLEESNGFTISEHDDFVKSVPRKNNPTDLLYSGKLLDSDEPPSVHGNSSKVPSKHPSPSFPETTSLRNLQNGSKQKPALPNFNDPHFYNEDVTRSGHPNRSIYTQLPRNEFSNARVLWNRLSARDRVLWRWANVENLDSFLQQVYTYYTGKGLSCIIVHRLFQILTVSFVIGFTTFITSCIDWPAVTPHGSLAGVTKSQCIAQMSPITYLVLWLFLSFLLALWIYYLTDIPRLWQMREFYIHALKIATADMPTVSWQRVLYRLLKLKNVNALTA... | autophagosome assembly macroautophagy nucleophagy protein localization to phagophore assembly site autophagosome; cytoplasmic vesicle membrane; endoplasmic reticulum membrane; fungal-type vacuole membrane; Golgi membrane; phagophore assembly site; phagophore assembly site membrane phospholipid scramblase activity Schiz... |
amino acid transmembrane import into vacuole amino acid transmembrane transport L-arginine transmembrane import into vacuole L-glutamate import involved in cellular response to nitrogen starvation L-glutamate transmembrane import into vacuole L-histidine transmembrane import into vacuole L-lysine import into vacuole in... | fungal-type vacuole membrane | L-arginine transmembrane transporter activity L-glutamate transmembrane transporter activity L-histidine transmembrane transporter activity L-lysine transmembrane transporter activity L-serine transmembrane transporter activity L-tyrosine transmembrane transporter activity | Schizosaccharomyces pombe | Amino-acid transport Membrane Reference proteome Sporulation Transmembrane Transmembrane helix Transport Vacuole | MSGYSPLSSG | MSGYSPLSSGPADVHIGKAGFFSSVINLANTILGAGILSLPNAFTKTGLLFGCLTIVFSAFASFLGLYFVSQCAARLPRGKASFAAVAKHTFPSLAVVFDASIAVKCFGVAVSYLVIVGDLMPQIAPSLGLSSPMFLRRQTWIVFALFVLTPLSFLKRLDSLRHTSVISLIALCYLVFIVLYHFIIGDTVKGEIRYFVPESGFGYLSVLPVFVFGFTCHQNAFSVINEVRNFSQGFVNFTMFTAIISSTLLYLLVAITGYLSFGSLASGNIIAMYDNTSIWIIGGKLAIVVLVLFSYPLQCHPCRNSVYQAIRRSYSAHD... | amino acid transmembrane import into vacuole amino acid transmembrane transport L-arginine transmembrane import into vacuole L-glutamate import involved in cellular response to nitrogen starvation L-glutamate transmembrane import into vacuole L-histidine transmembrane import into vacuole L-lysine import into vacuole in... |
mitotic cytokinesis positive regulation of G2/M transition of mitotic cell cycle | medial cortical node; mitotic actomyosin contractile ring; mitotic actomyosin contractile ring, intermediate layer | cytoskeletal protein-membrane anchor activity | Schizosaccharomyces pombe | Cell cycle Cell division Coiled coil Cytoplasm Cytoskeleton Mitosis Phosphoprotein Reference proteome | MSKSAFTSKS | MSKSAFTSKSQLKGIDGSFNDPFRQPSMNLPTPPHDDGLPSIPRSTALPNLSNRLSPYSHRNYLPIPEADSRNLEVLNSISLTTGSVVNQINKLYQRSCDNANYLQDLRSLILQTPTAEANATQVTESLNQIQKILQEASSKDREQIVQVIKELNKGNSLEVRRELGNCLAHLKKGTLNIDNALQASLQKYWKELQYFNVSKDKLLSLEESIKLLSARLEETDTPSSTHWIEINAGFKEVGDELSENFQRKQEILSGLQNNVILRTNNRKPVGSDGSNSNFNGGEEQMDSKDQEEIQDYLNSLLSVHEKDGVLLQKFHNS... | mitotic cytokinesis positive regulation of G2/M transition of mitotic cell cycle medial cortical node; mitotic actomyosin contractile ring; mitotic actomyosin contractile ring, intermediate layer cytoskeletal protein-membrane anchor activity Schizosaccharomyces pombe Cell cycle Cell division Coiled coil Cytoplasm Cyto... |
actin cortical patch localization DNA damage response endocytosis establishment or maintenance of cell polarity plasma membrane tubulation | actin cortical patch; mating projection tip; medial cortex; mitotic actomyosin contractile ring; Rvs161p-Rvs167p complex | lipid binding protein-membrane adaptor activity | Schizosaccharomyces pombe | Coiled coil Phosphoprotein Reference proteome SH3 domain | MSWKGFTKAL | MSWKGFTKALARTPQTLRSKFNVGEITKDPIYEDAGRRFKSLETEAKKLAEDAKKYTDAINGLLNHQIGFADACIEIYKPISGRASDPESYEQEGNAEGIEAAEAYKEIVYDLQKNLASEMDVINTRIVNPTGELLKIVKDVDKLLLKRDHKQLDYDRHRSSFKKLQEKKDKSLKDEKKLYEAETAFEQSSQEYEYYNEMLKEELPKLFALAQSFIAPLFQGFYYMQLNVYYVLYEKMSHCEIQYFDFNTDILESYERRRGDVKDRAEALTITKFKTAKPTYKRPGMGPGGKDATASSSSSFSSKREEAAAEPSSSTATD... | actin cortical patch localization DNA damage response endocytosis establishment or maintenance of cell polarity plasma membrane tubulation actin cortical patch; mating projection tip; medial cortex; mitotic actomyosin contractile ring; Rvs161p-Rvs167p complex lipid binding protein-membrane adaptor activity Schizosaccha... |
deactivation of mitotic spindle assembly checkpoint division septum assembly negative regulation of protein localization to mitotic spindle pole body negative regulation of septation initiation signaling positive regulation of G2/M transition of mitotic cell cycle rDNA heterochromatin formation | cytoplasm; mitotic spindle; nucleolus | phosphatase activator activity rDNA binding | Schizosaccharomyces pombe | Cell cycle Cell division Cytoplasm Cytoskeleton Mitosis Nucleus Phosphoprotein Reference proteome Septation | MRTTLRLHII | MRTTLRLHIIKDGEQDNQFMILFDPSSSISLLKEKVQETYKSLYPFESNINIRNIKNEESYDIPNEYLVGEIFPTNSKVIVESFSSPLKKLDGTMINFKEKNIQHDLDGVENDFATVQSASNGVHAINGKRTHPDESENPRKLPKKNFVEAIDANSPGFVYRPTSIRDRAYSISSNHDNESTLTEGIALKEIESPDKDRKADGIVNLSVTQEEDDNHQSFNSSLTPSQPTTYNRANFFSINDASSDSSSDAPLRTLSSPSRLRMKDNDRKYLVEHSPAALIKESETIDGIDDKSLRSSTREVSVESPNEDSVNDDSSSDV... | deactivation of mitotic spindle assembly checkpoint division septum assembly negative regulation of protein localization to mitotic spindle pole body negative regulation of septation initiation signaling positive regulation of G2/M transition of mitotic cell cycle rDNA heterochromatin formation cytoplasm; mitotic spind... |
establishment or maintenance of bipolar cell polarity negative regulation of cell wall integrity MAPK cascade positive regulation of establishment of bipolar cell polarity positive regulation of establishment of cell polarity regulating cell shape regulation of actin filament bundle assembly regulation of cell wall org... | cell periphery; cytoplasm; lateral cell cortex; lateral plasma membrane; medial cortex | GTPase activator activity metal ion binding small GTPase binding | Schizosaccharomyces pombe | GTPase activation LIM domain Metal-binding Phosphoprotein Reference proteome Repeat Zinc | MNSGTTLHLD | MNSGTTLHLDRLSLETPSERTCFCIKCWESVPSTSQVWFGGKCWHSDCFKCVNCNKKLDPSSEDFSQDDQKQIFCKLCVDICNGCSTPICEFNAVSNSQANHPCCSNCRAFINSNAFGKFKGQHYCLPCLRKQDEENQKAVMESASGFIPLRNIAQTAENTSLTGQNQGFQNPHFIASDSPSSVLSGRMQNTSSPTNSLRPQLKVQTNGYETPGDINSAKSYKDIQKDFLLKPKNSFVKTSPSPLANGPSFRSANASPFDSCDSFHSGSSIPIEPVSSRQSSVVNNNSVQQPVAYHAFVQSPTENGTLPQLPKNESVVNP... | establishment or maintenance of bipolar cell polarity negative regulation of cell wall integrity MAPK cascade positive regulation of establishment of bipolar cell polarity positive regulation of establishment of cell polarity regulating cell shape regulation of actin filament bundle assembly regulation of cell wall org... |
chromatin remodeling regulation of transcription by RNA polymerase II transcription initiation-coupled chromatin remodeling | chromatin; nucleus; SWI/SNF complex | transcription cis-regulatory region binding | Schizosaccharomyces pombe | Activator Chromatin regulator DNA-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MNNQGFVPAS | MNNQGFVPASDYPTAVSYPTQGQSYNTQEEQPAYPQRFSTSQGMYAAEYGNANMMNTSENEPNNLAHSQPFRQSPSTQRNLPNQSFDFASNGAWNGSGSVKYSSPMMPSSRIPFQQEKEAAMQQQQQQQQQQQLYQRQMQSREALLSQQIPPNQIGINAHPAVRQTPQPAPSPNTPSGNANQLTPAYAASFDKFMVSLISFMEKRGTPIKSYPQINNTPINLMMLYALVMRAGGSRQVSAHNFWPKISASLGFPSPDAISLLIQYYNSYLLPYEEAWLAAQQQQKSLQQAKANHSANVQSRPKNYPQKPVQTTPEAVHAN... | chromatin remodeling regulation of transcription by RNA polymerase II transcription initiation-coupled chromatin remodeling chromatin; nucleus; SWI/SNF complex transcription cis-regulatory region binding Schizosaccharomyces pombe Activator Chromatin regulator DNA-binding Nucleus Phosphoprotein Reference proteome Trans... |
cell wall organization ceramide biosynthetic process sphingoid catabolic process sphingolipid catabolic process | cell periphery; endoplasmic reticulum; endoplasmic reticulum membrane; fungal-type vacuole; membrane; plasma membrane | inositol phosphosphingolipid phospholipase activity mannosyl-inositol phosphorylceramide phospholipase activity metal ion binding sphingomyelin phosphodiesterase activity | Schizosaccharomyces pombe | Cell membrane Cell wall biogenesis/degradation Endoplasmic reticulum Hydrolase Lipid metabolism Magnesium Membrane Metal-binding Reference proteome Sphingolipid metabolism Transmembrane Transmembrane helix | MSVEKAPELR | MSVEKAPELRVLSFNCWGLRFVSKYRTERLKAVGEKLAKCDYDIVLLQEVWSIYDFQEIRNLVSCNLVYSRFFHSAAMGAGLAMFSKFPIIESSMNKYPLNGRPQAFWRGDWYVGKGVATASLQHPSGRIISLFNTHLHAPYGKGADTYLCHRLSQAWYISKLLRAAVQRGHIVIAAGDFNIQPLSVPHEIITSYGLVNDAWLSVYPDQVEHPPNRFSMNDKELVEIAGTTCDSRLNTWRENISSKDMDDFVAKRLDYVFHSPSTCEAKNAKVVFLERVPKLDCSYSDHFAIETVLSIKLQPIPVQETRVSYSIIDDTLG... | cell wall organization ceramide biosynthetic process sphingoid catabolic process sphingolipid catabolic process cell periphery; endoplasmic reticulum; endoplasmic reticulum membrane; fungal-type vacuole; membrane; plasma membrane inositol phosphosphingolipid phospholipase activity mannosyl-inositol phosphorylceramide p... |
protein targeting to membrane sporulation resulting in formation of a cellular spore | endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum palmitoyltransferase complex; Golgi apparatus; Golgi cisterna membrane | protein-cysteine S-palmitoyltransferase activity | Schizosaccharomyces pombe | Acyltransferase Endoplasmic reticulum Golgi apparatus Lipoprotein Membrane Palmitate Reference proteome Sporulation Transferase Transmembrane Transmembrane helix | MSYEKHSDAK | MSYEKHSDAKASRYAWNQPWNPFEVTLSDPTYPMNLEEKNQIPYRFQSVPDDVPEVPHIESRYKNLPGNNIYLCCGRLQMSSQYKAFLISLFALILPGVLFFIFSAFWLWHHVSPAVPITFAYLYALAVVSMFKCSTADPGILPRNAYSLTYNPAHPWSVIPEDRKVLVGSTRSDSVFVNTVYCHTCHLYRPPRASHCHLCDNCVEYLDHHCIWLNTCIGRRNYRYYFIFLLSVVLSALYLTGLGFYTSIGSFHESTDTNFAAHLRRPWAGVSFFLGIYGALGAILPGILFCYQCYLISVGQNVHEYLRAKSTETEDVHP... | protein targeting to membrane sporulation resulting in formation of a cellular spore endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum palmitoyltransferase complex; Golgi apparatus; Golgi cisterna membrane protein-cysteine S-palmitoyltransferase activity Schizosaccharomyces pombe Acyltransfe... |
actin cortical patch assembly actin cytoskeleton organization actin filament organization endocytosis | actin cortical patch; clathrin vesicle coat; endosome; plasma membrane | clathrin binding phosphatidylinositol-4,5-bisphosphate binding phospholipid binding ubiquitin binding | Schizosaccharomyces pombe | Cytoplasm Endocytosis Lipid-binding Membrane Phosphoprotein Reference proteome Repeat | MKAAVRSVKN | MKAAVRSVKNFSKGYTDTQIKVRNATTNDSWGPSGTAMAEIAELTYDQNEMLEVMDIIDRRLNDKGKNWRHVFKSLSLLEYCLHNGSENVVRWAKDNIYIITTLREFVYVDDNGHDQGQNVRTKAKEITSLLEDEHALKEARGDSRERDRDRDRTRSSRFDDDDDDRAPYEESRLSRAPSRASRYDDDDRDHRSRRRSRSRRPGRSRSRRRSRRPSPSAEHNSAEENDPELQRVIEESKRQAEEDAKRRNMANDSEAELQKAIQLSKEEDEARQRHQREREQQEQAFMGNQQNAYQPVDFFGNPVQPQPTGFLQQQPTGF... | actin cortical patch assembly actin cytoskeleton organization actin filament organization endocytosis actin cortical patch; clathrin vesicle coat; endosome; plasma membrane clathrin binding phosphatidylinositol-4,5-bisphosphate binding phospholipid binding ubiquitin binding Schizosaccharomyces pombe Cytoplasm Endocyto... |
inositol metabolic process inositol phosphate biosynthetic process inositol phosphate metabolic process mitotic spindle assembly phosphorylation regulation of bipolar cell growth regulation of microtubule cytoskeleton organization regulation of mitotic spindle elongation (spindle phase three) signaling | cytoskeleton; cytosol; nucleus | 2 iron, 2 sulfur cluster binding ATP binding ATP hydrolysis activity diphosphoinositol-pentakisphosphate kinase activity inositol heptakisphosphate kinase activity inositol hexakisphosphate 1-kinase activity inositol hexakisphosphate 3-kinase activity inositol hexakisphosphate 5-kinase activity inositol hexakisphosphat... | Schizosaccharomyces pombe | 3D-structure ATP-binding Cytoplasm Cytoskeleton Kinase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Transferase | MIQNASHLTS | MIQNASHLTSIDTESSTRTASPVSSIVTPTKRNVVGICAMDAKARSKPCRNILNRIIAEGEFEAIVFGDNMILDEAVENWPACDYLICFYSSGFPLKKAEKYVELRKPFCVNDVVFQELLWDRRLVLNILDAIRVSTPQRLICSRDGGPKINKVLEEKLRRKFGIEITEVPTPEVKMLDEDTLSVDGKIIKKPYVEKPVYGEDHNIYIYFPKSVGGGGRKLFRKVANKSSDYDPDLCAPRTEGSFIYEEFMNVDNAEDVKVYTVGPHYSHAETRKSPVVDGIVRRNPHGKEIRFITNLSEEEKNMASKISIAFEQPVCGF... | inositol metabolic process inositol phosphate biosynthetic process inositol phosphate metabolic process mitotic spindle assembly phosphorylation regulation of bipolar cell growth regulation of microtubule cytoskeleton organization regulation of mitotic spindle elongation (spindle phase three) signaling cytoskeleton; cy... |
cell division mitotic spindle pole body duplication proteasome-mediated ubiquitin-dependent protein catabolic process protein localization to meiotic spindle pole body spindle pole body duplication | cytosol; half bridge of mitotic spindle pole body; half bridge of spindle pole body; meiotic spindle pole body; mitotic spindle pole body; nucleus | calcium ion binding microtubule binding | Schizosaccharomyces pombe | Calcium Cell cycle Cell division Metal-binding Mitosis Nucleus Reference proteome Repeat | MFANARAKRR | MFANARAKRRSRASSPTPARLGGYAPLRVEITEEQRQDINEAFKLFDSDKDNAIDYHELRAAMRALGFNAEKSEVLKILRDFDKTGKGYLQMEDFVRVMTEKIVERDPLEEIKRAFELFDDDETGKISLRNLRRVAKELNENIDDQELEAMIEEFDLDQDGEINEQEFIAIMMDEA | cell division mitotic spindle pole body duplication proteasome-mediated ubiquitin-dependent protein catabolic process protein localization to meiotic spindle pole body spindle pole body duplication cytosol; half bridge of mitotic spindle pole body; half bridge of spindle pole body; meiotic spindle pole body; mitotic sp... |
macroautophagy protein transport transmembrane transport | endoplasmic reticulum membrane; Golgi apparatus; membrane; phagophore assembly site; phagophore assembly site membrane | choline transmembrane transporter activity transmembrane transporter activity | Schizosaccharomyces pombe | Autophagy Endoplasmic reticulum Glycoprotein Membrane Protein transport Reference proteome Transmembrane Transmembrane helix Transport | MFSDYASRFL | MFSDYASRFLAQSRFSSVDQRNFKYPTSRSNLQSVSIDRNSSIDSHETDLSAGSSSLHGLNSLIDSGSIHWQLREQEQSNSHISRNENELFSKENSIYNGNFSENLGVQPNPQTISHESVNEEYTELPYDAHLPSEQKVPDRKWGLTFGFLTLALFTYSFLMVWRTNPNIPPATSPYAAIQKAFPLFHKDAIICMMLSVIWLFCLVAIPRFLYFLLASVPLTMFAFAVYLLKASRIHLETSIQPKLMLLTGIILLVAPILLSYYVWRRRIHFETSFNIIRLACRVIADIPQITLIFISFLFSFYVLIFIWVRLFARLFLR... | macroautophagy protein transport transmembrane transport endoplasmic reticulum membrane; Golgi apparatus; membrane; phagophore assembly site; phagophore assembly site membrane choline transmembrane transporter activity transmembrane transporter activity Schizosaccharomyces pombe Autophagy Endoplasmic reticulum Glycopr... |
negative regulation of mitotic cohesin loading phosphorylation regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process signal transduction traversing start control point of mitotic cell cycle | ascospore-type prospore; cytoplasm; cytosol; nucleus | ATP binding cyclin-dependent protein serine/threonine kinase activity protein serine kinase activity | Schizosaccharomyces pombe | ATP-binding Kinase Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MNYQRLEKLG | MNYQRLEKLGEGTYAHVYKGQNRVTGEIVALKVIRIDADEGTPSTAIREISLMKELRHPNIMSLSDVLQTENKLMLVFEYMEKDLKKYMDTYGNQGALPPSQVKNFTQQLLKGISFCHENRVLHRDLKPQNLLINSRGELKLADFGLARSIGIPVNTFSNEVVTLWYRAPDVLLGSRVYSTSIDIWSVGCIMAEMATGRPLFAGSNNEDQLLKIFRLLGTPTEQSWPGISLLPEYKPTFPIYKAQDLAYLFPTFDPLGLDLLRRMLRLQPELRTTGQDALQHAWFLTA | negative regulation of mitotic cohesin loading phosphorylation regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process signal transduction traversing start control point of mitotic cell cycle ascospore-type prospore; cytoplasm; cytosol; nucleus ATP binding cyclin-dep... |
chromosome segregation pericentric heterochromatin formation regulatory ncRNA-mediated heterochromatin formation | cytosol; nuclear RNA-directed RNA polymerase complex; nucleus; RNA-directed RNA polymerase complex | ATP binding ATP hydrolysis activity RNA binding RNA helicase activity | Schizosaccharomyces pombe | ATP-binding Cell cycle Chromosome partition Cytoplasm Helicase Hydrolase Nucleotide-binding Nucleus Phosphoprotein Reference proteome RNA-binding RNA-mediated gene silencing | MEQVQDEIWK | MEQVQDEIWKLSTLDAWEMVNKNTEVVFDEIPEPETLSEMKRHPLYSNIFNADNNTTSFTEQIETSETSKTQDSEGNKVDKNLKENKSIRRKRSIDNDYELSNVKRNDITSGKNREFENEHHPASDTSSWRELPSIPTLEELTSKSVELPSNNIYGGYKSFEDYLSIHYRLLREDAVSPLRESVLRYKVNPNYITGSSLAVYDHVRIDGYTISSSVIAAKLSFSVRAKKKIKWATSRRLISGSLVLLSNDDFQTFRIGTVCARPLSGLNKHPHEIDVKFEDISISLDPREEYVMIEATSGYWEAYKHVLRSLQRLSASTF... | chromosome segregation pericentric heterochromatin formation regulatory ncRNA-mediated heterochromatin formation cytosol; nuclear RNA-directed RNA polymerase complex; nucleus; RNA-directed RNA polymerase complex ATP binding ATP hydrolysis activity RNA binding RNA helicase activity Schizosaccharomyces pombe ATP-binding... |
exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of 5.8S rRNA nonfunctional rRNA decay nuclear mRNA surveillance nuclear polyadenylation-dependent mRNA catabolic process nuclear polyadenylation-dependent rRNA catabolic process nu... | cytosol; exosome (RNase complex); nuclear exosome (RNase complex); nucleolus; nucleus | DNA binding RNA binding | Schizosaccharomyces pombe | Cytoplasm Exosome Nucleus Reference proteome RNA-binding rRNA processing | MDPEYSELFE | MDPEYSELFERLNKQLDNVEDVLKPLKDAESIFELAEGKSELEQAKLYITMSYAINSTLYSFYKLNGIDASERPVMQELQRVKNYISKIQQAEKNVNPKTEAVNTSNAAISSSSSNRPKVAKDAATRIIKHHT | exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of 5.8S rRNA nonfunctional rRNA decay nuclear mRNA surveillance nuclear polyadenylation-dependent mRNA catabolic process nuclear polyadenylation-dependent rRNA catabolic process nu... |
maturation of SSU-rRNA mRNA cis splicing, via spliceosome nuclear-transcribed mRNA catabolic process telomerase holoenzyme complex assembly tRNA processing | catalytic step 2 spliceosome; cytosol; Lsm1-7-Pat1 complex; Lsm2-8 complex; nucleus; spliceosomal tri-snRNP complex; telomerase holoenzyme complex; U2 snRNP; U2-type prespliceosome; U4/U6 x U5 tri-snRNP complex; U5 snRNP; U6 snRNP | poly(U) RNA binding U2 snRNA binding | Schizosaccharomyces pombe | 3D-structure Cytoplasm mRNA processing mRNA splicing Nucleus Reference proteome Ribonucleoprotein RNA-binding rRNA processing Spliceosome tRNA processing | MSSLQKRPGP | MSSLQKRPGPGNSSQPTERPRKESILDLSRYQDQRIQATFTGGRQITGILKGFDQLMNLVLDDVEEQLRNPEDGKLTGAIRKLGLVVVRGTTLVLIAPMDGSEEIPNPFVQAE | maturation of SSU-rRNA mRNA cis splicing, via spliceosome nuclear-transcribed mRNA catabolic process telomerase holoenzyme complex assembly tRNA processing catalytic step 2 spliceosome; cytosol; Lsm1-7-Pat1 complex; Lsm2-8 complex; nucleus; spliceosomal tri-snRNP complex; telomerase holoenzyme complex; U2 snRNP; U2-typ... |
cell cycle cell division negative regulation of protein localization to kinetochore signaling | chromatin; cytosol; nucleoplasm; nucleus; protein serine/threonine phosphatase complex | protein phosphatase activator activity protein phosphatase binding protein phosphatase regulator activity | Schizosaccharomyces pombe | Cell cycle Cell division Mitosis Nucleus Phosphoprotein Reference proteome | MFWRLGQGFG | MFWRLGQGFGFQSSSAIEAILDKPEDEINLKELLEENGVLDECKSHNPKLLEYLCKPEVLSQLIDYILEVDETEIPSADGGYEEPEHTRLSYIASEILSSDVWSICEACVENKTLMVKLWSFLDSEGPLNPLQASYFAKVNEHFLDKKTEETVAFIQSIDNFVEKILRHAETSAIMDLLLKFISMDRCNTAIGIADWLYSQGLIQSLLRLLSPYVDPDVQFTVADVIKAIIAISANSNEPGVIGPNSLSRELVSRQTITTLTDYMTDSKAPHSATSLINGVSIVIELIRKNNSDYDVTPVLQMPLDTHPPTTRDPIYLGT... | cell cycle cell division negative regulation of protein localization to kinetochore signaling chromatin; cytosol; nucleoplasm; nucleus; protein serine/threonine phosphatase complex protein phosphatase activator activity protein phosphatase binding protein phosphatase regulator activity Schizosaccharomyces pombe Cell c... |
chromosome segregation pericentric heterochromatin formation regulatory ncRNA-mediated heterochromatin formation RNA 3'-end processing | cytosol; nuclear RNA-directed RNA polymerase complex; nucleolus; nucleus; RNA-directed RNA polymerase complex; TRAMP complex | ATP binding metal ion binding poly(A) RNA polymerase activity RNA binding | Schizosaccharomyces pombe | ATP-binding Cell cycle Chromosome partition Cytoplasm Magnesium Manganese Metal-binding Nucleotide-binding Nucleus Phosphoprotein Reference proteome RNA-binding RNA-mediated gene silencing Transferase | MGKVLLELHS | MGKVLLELHSVPWNEEGLSDNARLYSFLEFVSPKIEELKYRKLLLEKLQTHIREVVLDAELQVYGSMYIGTTLSISDVDVSLKSPRVGELEKRRVTMVLRKYLDADADFHSSARVPRINLVDVSGIGVDLTFGNDKACRTAELQKAYNEEHPIFGRLLMLLKHWLFERDLENVHHGGIASCALSYMLIGWLEMRFHKKGIDSEVQPIRALLQKFFYFWGVEWTYELFVLRPLTGQIVPKLQKGWLNEVQPNLLSIEDPIDRNNDIGKQSFQISMIKAAFVASANELLSDKTWFSTFAITEDEMFLCKQFENVINTKRSLV... | chromosome segregation pericentric heterochromatin formation regulatory ncRNA-mediated heterochromatin formation RNA 3'-end processing cytosol; nuclear RNA-directed RNA polymerase complex; nucleolus; nucleus; RNA-directed RNA polymerase complex; TRAMP complex ATP binding metal ion binding poly(A) RNA polymerase activit... |
CAMKK-AMPK signaling cascade carbohydrate metabolic process induction of conjugation with cellular fusion intracellular signal transduction negative regulation of cytoplasmic translation negative regulation of TORC1 signaling phosphorylation positive regulation of ascus development positive regulation of cell cycle swi... | cytoplasm; cytosol; mitotic spindle pole body; nucleotide-activated protein kinase complex; nucleus | ATP binding protein serine kinase activity protein serine/threonine kinase activity | Schizosaccharomyces pombe | 3D-structure ATP-binding Carbohydrate metabolism Cytoplasm Kinase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MQPQEVDLME | MQPQEVDLMENSTMRNGARVLPPEAISKRHIGPYIIRETLGEGSFGKVKLATHYKTQQKVALKFISRQLLKKSDMHMRVEREISYLKLLRHPHIIKLYDVITTPTDIVMVIEYAGGELFDYIVEKKRMTEDEGRRFFQQIICAIEYCHRHKIVHRDLKPENLLLDDNLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVINGKLYAGPEVDVWSCGIVLYVMLVGRLPFDDEFIPNLFKKVNSCVYVMPDFLSPGAQSLIRRMIVADPMQRITIQEIRRDPWFNVNLPDYLRPMEEVQGSYADSRIVSKLGEAMGFSE... | CAMKK-AMPK signaling cascade carbohydrate metabolic process induction of conjugation with cellular fusion intracellular signal transduction negative regulation of cytoplasmic translation negative regulation of TORC1 signaling phosphorylation positive regulation of ascus development positive regulation of cell cycle swi... |
mRNA cis splicing, via spliceosome regulation of mRNA splicing, via spliceosome | commitment complex; cytosol; nucleus; U2-type prespliceosome | mRNA binding RNA binding zinc ion binding | Schizosaccharomyces pombe | Cytoplasm Metal-binding mRNA processing mRNA splicing Nucleus Phosphoprotein Reference proteome Repeat RNA-binding Spliceosome Zinc Zinc-finger | MLNSRSVGST | MLNSRSVGSTGSNNTPLGRRRFDEKPDSLPPLPDANGMSNGYRDSYKSNSRMDHRPDGYHDGRGRRAYRKHYWGHPTPIEEMLPSQMELETAVKSCMTMEQLELYSLNVRLEEITQKLRTGDVVPHHRERSPSPPPQYDNHGRRLNTREIRYKKKLEDERHRIIERAMKMVPGFRAPSDYRRPAKTQEKVYVPVKDYPEINFIGLLIGPRGHTLKDMEAKSGAKIAIRGKGSVKEGKGRSDPSVRGNMEEDLHCLVTADSEDKINHAIKLIDNVIQTAASVPEGQNDLKRNQLRQLATLNGTLRDDENQVCQNCGNVGHR... | mRNA cis splicing, via spliceosome regulation of mRNA splicing, via spliceosome commitment complex; cytosol; nucleus; U2-type prespliceosome mRNA binding RNA binding zinc ion binding Schizosaccharomyces pombe Cytoplasm Metal-binding mRNA processing mRNA splicing Nucleus Phosphoprotein Reference proteome Repeat RNA-bin... |
cell cycle cell division positive regulation of protein phosphorylation RAM/MOR signaling pathway regulation of establishment or maintenance of bipolar cell polarity regulating cell shape signal transduction | cell cortex; cell division site; cell tip; cytoplasm; nucleus | protein kinase activator activity | Schizosaccharomyces pombe | Cell cycle Cell division Cytoplasm Mitosis Phosphoprotein Reference proteome | MFLLNSLSRI | MFLLNSLSRITRGNRSKRHQNLSDASSSSGSFSKKSSTSQLVRTGSPSVEPTALYLQQPFVRTHLVKGNFSTIVSLPRFVDLDEWVALNVYELFTYLNHFYDVFATFCTVKTCPVMSAAANFDYTWLDNNRKPVHLPAPQYIEYVLAWIENRLHDQNVFPTKAGLPFPSNFLVIVKAIYKQMFRIFAHMYYAHYAEILHLSLEAHWNSFFAHFIAFGKEFQLLDKRDTAPLKDLIVVLENQGNI | cell cycle cell division positive regulation of protein phosphorylation RAM/MOR signaling pathway regulation of establishment or maintenance of bipolar cell polarity regulating cell shape signal transduction cell cortex; cell division site; cell tip; cytoplasm; nucleus protein kinase activator activity Schizosaccharomy... |
epigenetic regulation of gene expression protein ubiquitination transcription elongation-coupled chromatin remodeling | HULC complex; nucleus | histone H2B C-terminal K residue ubiquitin ligase activity ubiquitin protein ligase activity zinc ion binding | Schizosaccharomyces pombe | Chromatin regulator Coiled coil Metal-binding Nucleus Reference proteome Transferase Ubl conjugation pathway Zinc Zinc-finger | MYQNGKPDAP | MYQNGKPDAPTILGQKRELEDVEIQDDDIQEVSKEDLLKDVRVRSIQFDELESKIEGLQNLAEEKLKVLATLVSWWPEILQQFSVVFQGNELKDFESEGVFSILEKFPELSYFNDAVKNNKTKALSIIQKLLSTVDSSTNSVSRDPFSVLSIDDSALTEKLNTINLDIDKILDELDTTRSQLHSIIKLPDRSSSFTLQCINESVRPQSTKVKEEATTSSKGKDEEKKVSTVEQRTQLQQLSRLQDQQNGLMESRSQSLKILDSNVNEMDKLIMERENALNNVETTNLKKYSSFLALKEAVSMTSEQLRVLEHLLSECSHE... | epigenetic regulation of gene expression protein ubiquitination transcription elongation-coupled chromatin remodeling HULC complex; nucleus histone H2B C-terminal K residue ubiquitin ligase activity ubiquitin protein ligase activity zinc ion binding Schizosaccharomyces pombe Chromatin regulator Coiled coil Metal-bindi... |
cell cycle cell division positive regulation of DNA-templated transcription, elongation regulation of transcription by RNA polymerase II signaling | cyclin-dependent protein kinase holoenzyme complex; cyclin/CDK positive transcription elongation factor complex; cytosol; nucleus; P-TEFb complex | cyclin-dependent protein serine/threonine kinase activator activity | Schizosaccharomyces pombe | Cell cycle Cell division Cyclin Nucleus Phosphoprotein Reference proteome | MSEVIKSVPP | MSEVIKSVPPGSQNTSQWIISKDQLVFTPSALDGIPLDQEEIQRSKGCNFIINVGLRLKLPQTALATANIYFHRFYLRFSLKNYHYYEVAATCIFLATKVEDSVRKLRDIVINCAKVAQKNSNVLVDEQTKEYWRWRDVILYTEEVLLEALCFDFTVEHPYPYVLSFIKKFVADDKNVTKVAWTYINDSTRSIACLLYSPKTIAAAAFQFALEKNEINLSTTTDGLPVWMEESQVSYEDVKGVLTLIDSLYKKINPSKQALPIDQKNGSHASSVAPGTPSSLASVSTQATPQHQNSSGRTDSFHSLNTETPSKSTVDDQI... | cell cycle cell division positive regulation of DNA-templated transcription, elongation regulation of transcription by RNA polymerase II signaling cyclin-dependent protein kinase holoenzyme complex; cyclin/CDK positive transcription elongation factor complex; cytosol; nucleus; P-TEFb complex cyclin-dependent protein se... |
polysaccharide catabolic process | extracellular region | inulinase activity | Aspergillus niger | Carbohydrate metabolism Glycoprotein Glycosidase Hydrolase Polysaccharide degradation Secreted Signal | MLNPKVAYMV | MLNPKVAYMVWMTCLGLMLPSQAQSNDYRPSYHFTPDQYWMNEPNGLIKIGSTWHLFFQHNPTANVWGNICWGHATSTDLMHWAHKPTAIADENGVEAFTGTAYYDPNNTSGLGDSANPPYLAWFTGYTTSSQTQDQRLAFSVDNGATWTKFQGNPIISTSQEAPHDITGGLESRDPKVFFHRQSGNWIMVLAHGGQDKLSFWTSADTINWTWQSDLKSTSINGLSSDITGWEVPDMFELPVEGTEETTWVVMMTPAEGSPAGGNGVLAITGSFDGKSFTADPVDASTMWLDNGRDFDGALSWVNVPASDGRRIIAAVMN... | polysaccharide catabolic process extracellular region inulinase activity Aspergillus nigerCarbohydrate metabolism Glycoprotein Glycosidase Hydrolase Polysaccharide degradation Secreted Signal MLNPKVAYMV MLNPKVAYMVWMTCLGLMLPSQAQSNDYRPSYHFTPDQYWMNEPNGLIKIGSTWHLFFQHNPTANVWGNICWGHATSTDLMHWAHKPTAIADENGVEAFTGTAYYDPNNTSGLGDSA... |
endosome organization exocytosis receptor recycling retrograde transport, endosome to Golgi | cell cortex of cell tip; cell division site; cell tip; cytosol; early endosome; medial cortex; membrane; recycling endosome; trans-Golgi network | lipid binding | Schizosaccharomyces pombe | Cytoplasm Membrane Phosphoprotein Reference proteome SH3 domain | MASQRFVIAL | MASQRFVIALHSFPGKSSDELPLVEGRKYLLIKMDEEFGDGWWEGEDEQGNRGIFPASHVELISDERSDSSDSRRGKEDFSISTAEVTRSSLSSSRSTSSRSDKDSEKLYSNNSLSSSHSSILNGPLDSLSKPSVPSNFNSMFPSSKQEGPSPLLDNQPSSDLSNFNTIDADYNNASASTSAPATSASLKKVLSAEDSVRETITDIETALQNMSTSASRTPNDSSPLPYIENRPASSLAVSEKIQNVPNWSTEEVVEWLMNAGLGSVAPNFAENEITGEILLGLDSNVLKELNITSFGKRFEVLRKIQQLKDSYEQSLYE... | endosome organization exocytosis receptor recycling retrograde transport, endosome to Golgi cell cortex of cell tip; cell division site; cell tip; cytosol; early endosome; medial cortex; membrane; recycling endosome; trans-Golgi network lipid binding Schizosaccharomyces pombe Cytoplasm Membrane Phosphoprotein Referenc... |
protein insertion into mitochondrial inner membrane | mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrial intermembrane space protein transporter complex; mitochondrion; TIM22 mitochondrial import inner membrane insertion complex | metal ion binding protein transporter activity unfolded protein binding | Saccharomyces cerevisiae | 3D-structure Acetylation Chaperone Direct protein sequencing Disulfide bond Membrane Metal-binding Mitochondrion Mitochondrion inner membrane Protein transport Reference proteome Translocation Transport Zinc | MDALNSKEQQ | MDALNSKEQQEFQKVVEQKQMKDFMRLYSNLVERCFTDCVNDFTTSKLTNKEQTCIMKCSEKFLKHSERVGQRFQEQNAALGQGLGR | protein insertion into mitochondrial inner membrane mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrial intermembrane space protein transporter complex; mitochondrion; TIM22 mitochondrial import inner membrane insertion complex metal ion binding protein transporter activity unfolded protein b... |
cytoplasmic translational termination nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay translation | cytosol; translation release factor complex | GTP binding GTPase activity translation release factor activity | Schizosaccharomyces pombe | 3D-structure Cytoplasm GTP-binding Hydrolase Nucleotide-binding Phosphoprotein Protein biosynthesis Reference proteome Repeat | MASNQPNNGE | MASNQPNNGEQDEQLAKQTSKLSMSAKAPTFTPKAAPFIPSFQRPGFVPVNNIAGGYPYAQYTGQGQNSNSPHPTKSYQQYYQKPTGNTVDEDKSRVPDFSKKKSFVPPKPAIPKGKVLSLGGNTSAPKSTKPISISLGGTKAPTTTKPAAPAAQSKTETPAPKVTSESTKKETAAPPPQETPTKSADAELAKTPSAPAAALKKAAEAAEPATVTEDATDLQNEVDQELLKDMYGKEHVNIVFIGHVDAGKSTLGGNILFLTGMVDKRTMEKIEREAKEAGKESWYLSWALDSTSEEREKGKTVEVGRAYFETEHRRFSL... | cytoplasmic translational termination nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay translation cytosol; translation release factor complex GTP binding GTPase activity translation release factor activity Schizosaccharomyces pombe 3D-structure Cytoplasm GTP-binding Hydrolase Nucleotide-bindi... |
DNA repair-dependent chromatin remodeling regulation of DNA-templated transcription | cytosol; NuA4 histone acetyltransferase complex; nucleus; Rpd3L complex | metal ion binding methylated histone binding | Schizosaccharomyces pombe | 3D-structure Chromatin regulator Cytoplasm Metal-binding Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation Zinc Zinc-finger | MGTSGIEIFA | MGTSGIEIFAALNDFTDAIVSVPESVCGKFTSLKEIDAQVRDIRQNVIQEIGVVLKNEKNDELSGEERCERLQKTLKEILPYSDSKICLATDAMNNIKSCIDRLDAGFEYVELEIPQQLRLGYPDDRALMNYHSTVTPQTSERRRETRRHQNNQHSQQYSSQERSSSYNNFEDASSPQSSYHTPTKRRKNAVPRKSSSPPLSSTKHAPQSTERRPVRRSESRLKQTNGEPLVKHDTLDSSDISREGEQLYCYCQQVSYGQMIGCDNENCKREWFHLPCVGLVEPPKGIWYCKECEELAKSSESRQ | DNA repair-dependent chromatin remodeling regulation of DNA-templated transcription cytosol; NuA4 histone acetyltransferase complex; nucleus; Rpd3L complex metal ion binding methylated histone binding Schizosaccharomyces pombe 3D-structure Chromatin regulator Cytoplasm Metal-binding Nucleus Phosphoprotein Reference pr... |
ER-associated misfolded protein catabolic process mannoprotein catabolic process | cytosol; nuclear envelope; nucleus | metal ion binding misfolded protein binding peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity | Schizosaccharomyces pombe | Cytoplasm Hydrolase Metal-binding Nucleus Reference proteome Zinc | MDFHAISQRF | MDFHAISQRFIDMMRSKNSQNASQPPETYPFYHEVRQMSQHPWMYEDPELQDYALSILPLDKLFQDASELEKEGDGSWGYQDYVIQALLKWFKREFFVWVNQPPCEKCGGETHMTGNGPPNEEEKWNGVRNVELYQCNVCGHNQRFPRYNRIRALLDSRKGRCGEWANCFTFLCRALGSRARWIWNAEDHVWTEVYSNKQQRWVHVDSGEESFDEPLIYEQGWGKKMSYCLGFGIDSVRDVSHRYIRHPENGLPRDRCPESVLQQALHEINIEFRSRLTDSERKALEEEDKREKDELDGYMRPVSQATPTNTDLPARQTG... | ER-associated misfolded protein catabolic process mannoprotein catabolic process cytosol; nuclear envelope; nucleus metal ion binding misfolded protein binding peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity Schizosaccharomyces pombe Cytoplasm Hydrolase Metal-binding Nucleus Reference proteome Zinc ... |
cellular response to heat cytoplasm protein quality control protein aggregate center assembly protein refolding protein transport regulatory ncRNA-mediated heterochromatin formation | cytoplasm; cytosol; nucleus; protein aggregate center | ATP binding Hsp70 protein binding metal ion binding protein sequestering activity protein-folding chaperone binding unfolded protein binding | Schizosaccharomyces pombe | Chaperone Cytoplasm Lipoprotein Metal-binding Methylation Nucleus Prenylation Protein transport Reference proteome Repeat Transport Zinc Zinc-finger | MVKETKLYEV | MVKETKLYEVLNVDVTASQAELKKAYRKLALKYHPDKNPNAGDKFKEISRAYEILADEEKRATYDRFGEEGLQGGGADGGMSADDLFASFFGGGMFGGGMPRGPRKGKDLVHTIKVTLEDLYRGKTTKLALQKKVICPKCSGRGGKEGSVKSCASCNGSGVKFITRAMGPMIQRMQMTCPDCNGAGETIRDEDRCKECDGAKVISQRKILTVHVEKGMHNGQKIVFKEEGEQAPGIIPGDVIFVIDQKEHPRFKRSGDHLFYEAHVDLLTALAGGQIVVEHLDDRWLTIPIIPGECIRPNELKVLPGQGMLSQRHHQPGN... | cellular response to heat cytoplasm protein quality control protein aggregate center assembly protein refolding protein transport regulatory ncRNA-mediated heterochromatin formation cytoplasm; cytosol; nucleus; protein aggregate center ATP binding Hsp70 protein binding metal ion binding protein sequestering activity pr... |
formation of cytoplasmic translation initiation complex translation reinitiation | cytoplasm; cytoplasmic stress granule; eukaryotic 43S preinitiation complex; eukaryotic 48S preinitiation complex; eukaryotic translation initiation factor 3 complex; eukaryotic translation initiation factor 3 complex, eIF3e; eukaryotic translation initiation factor 3 complex, eIF3m; multi-eIF complex | mRNA binding translation initiation factor activity | Schizosaccharomyces pombe | Coiled coil Cytoplasm Initiation factor Phosphoprotein Protein biosynthesis Reference proteome RNA-binding | MAPPQGKPEN | MAPPQGKPENVLRLADELIALDQHSSALQSLHETIVLKRSRNAQGFSLEPIMMRFIELCVHLRKGKIAKEGLYTYKNAVQNTSVTAIENVVKHFIELANKRVQEAQEKADKISVEYVDDLEATETPESIMMSLVSGDLSKSRTDRALVTPWLKFLWDAYRTVLDILRNNARLEVMYQLIANSAFQFCLKYQRKTEFRRLCELLRSHLGNASKFSNAPHSINLNDAETMQRHLDMRFSQLNVAVELELWQEAFRSIEDIHSLLTFSKRAPAAVMLGNYYRKLIKIFLVCDNYLLHAAAWNRYFTFTNVQKPATANFVILSA... | formation of cytoplasmic translation initiation complex translation reinitiation cytoplasm; cytoplasmic stress granule; eukaryotic 43S preinitiation complex; eukaryotic 48S preinitiation complex; eukaryotic translation initiation factor 3 complex; eukaryotic translation initiation factor 3 complex, eIF3e; eukaryotic tr... |
cytoplasmic translational termination endoplasmic reticulum unfolded protein response nuclear-transcribed mRNA catabolic process, no-go decay translation | cytosol; Dom34-Hbs1 complex | GTP binding GTPase activity translation elongation factor activity translation release factor activity | Schizosaccharomyces pombe | 3D-structure Cytoplasm Elongation factor GTP-binding Hydrolase Nucleotide-binding Protein biosynthesis Reference proteome Translation regulation | MSRHRDVKNL | MSRHRDVKNLDLDDYELDEEPGEEELTEEQEEEFRSAVATVRETLLGVPISEKEIADTVWYYYFDVEKSVNYLLQKASSKAGAKEKQNTDSQKEKKQNKSKEALADAKDPLDESSNGIKNLSLNKNDEPAFQTNGEVKMKNSSESDNQPEKKKIKKQNPTDLVSVPEIFEQSNPKPVVHLVVTGHVDSGKSTMLGRIMFELGEINSRSMQKLHNEAANSGKGSFSYAWLLDTTEEERARGVTMDVASTTFESDKKIYEIGDAPGHRDFISGMIAGASSADFAVLVVDSSQNNFERGFLENGQTREHAYLLRALGISEIVV... | cytoplasmic translational termination endoplasmic reticulum unfolded protein response nuclear-transcribed mRNA catabolic process, no-go decay translation cytosol; Dom34-Hbs1 complex GTP binding GTPase activity translation elongation factor activity translation release factor activity Schizosaccharomyces pombe 3D-struc... |
protein transport rRNA processing | nucleolus; nucleus | GTP binding GTPase activity RNA binding | Schizosaccharomyces pombe | 3D-structure GTP-binding Nucleotide-binding Nucleus Protein transport Reference proteome Ribosome biogenesis RNA-binding rRNA processing Transport | MVSLKKKSKR | MVSLKKKSKRRTTRLRSRIEKKAAESKRKQKRADKKNPQWKSRIPKDPGIPNSFPYKDKILAEIEEQKRIREEEKLARRASGQVDAAMEEEDAVDENGSLMISKIAEAAQASNPDDEEEFVMEEDNLGEAPLLVDSESYEASVKADTSRKAYDKEFKKVVEASDVILYVLDARDPEGTRSKDVERQVLASSAEEKRLIFVINKIDLVPSEVLNKWVTYLRNFFPTIPMRSASGSGNSNLKHQSASASSTISNLLKSLKSYSAKKKLKSSLTVGVIGYPNVGKSSVINALVNRSANGRSAPCPAGNVAGMTTSLREVKLDN... | protein transport rRNA processing nucleolus; nucleus GTP binding GTPase activity RNA binding Schizosaccharomyces pombe 3D-structure GTP-binding Nucleotide-binding Nucleus Protein transport Reference proteome Ribosome biogenesis RNA-binding rRNA processing Transport MVSLKKKSKR MVSLKKKSKRRTTRLRSRIEKKAAESKRKQKRADKKNPQWKS... |
nucleotide-excision repair proteasome-mediated ubiquitin-dependent protein catabolic process ubiquitin-dependent ERAD pathway | cytosol; nuclear envelope; nucleoplasm; nucleus | damaged DNA binding polyubiquitin modification-dependent protein binding proteasome binding ubiquitin binding | Schizosaccharomyces pombe | DNA damage DNA repair Nucleus Phosphoprotein Reference proteome Repeat Ubl conjugation pathway | MNLTFKNLQQ | MNLTFKNLQQQKFVISDVSADTKISELKEKIQTQQNYEVERQKLIYSGRILADDKTVGEYNIKEQDFIVCMVSRPKTSTSTPKSAASPAPNPPASVPEKKVEAPSSTVAESTSTTQTVAAAAPSNPDTTATSEAPIDANTLAVGAQRNVAVENMVEMGYERSEVERAMRAAFNNPDRAVEYLLTGIPEDILNRQREESAAALAAQQQQSEALAPTSTGQPANLFEQAALSENENQEQPSNTVGDDPLGFLRSIPQFQQLRQIVQQNPQMLETILQQIGQGDPALAQAITQNPEAFLQLLAEGAEGESALPSGGIQIQITQ... | nucleotide-excision repair proteasome-mediated ubiquitin-dependent protein catabolic process ubiquitin-dependent ERAD pathway cytosol; nuclear envelope; nucleoplasm; nucleus damaged DNA binding polyubiquitin modification-dependent protein binding proteasome binding ubiquitin binding Schizosaccharomyces pombe DNA damag... |
DNA biosynthetic process DNA ligation involved in DNA repair DNA recombination double-strand break repair via classical nonhomologous end joining double-strand break repair via nonhomologous end joining nucleotide-excision repair, DNA gap filling | chromatin; DNA ligase IV complex; nucleolus; nucleus | ATP binding DNA binding DNA ligase (ATP) activity metal ion binding | Schizosaccharomyces pombe | ATP-binding DNA damage DNA recombination DNA repair Ligase Magnesium Metal-binding Nucleotide-binding Nucleus Reference proteome Repeat | MDEAKETVFT | MDEAKETVFTKPQNHSSTLEFYDFVTTLLEPLSRIGKTRKSKTSNLDPYELKRKILLDYFNKWRQHVGPDLYPLLRLMLPDLDRERGSYGFKEFGLGKLFIRAMHLSPTSEDAKSLKNWRGSESKHTGDFSTMLQDILQRRAYRTFPGAFTVGDVNALLDQLADASSEDTRVNILEQFYRSLSPLELRWLIPILLKVRKYGTSEKFILSVFHPDAARLYRLCSSLKRICWELYDPSRSLDETETDVEVFSCFQPQLANFKKKDLHQTLEAMGNKPFWIEEKLDGERIQLHMSSGKFQFYSRNARSYTYAYGSSYFDEQSR... | DNA biosynthetic process DNA ligation involved in DNA repair DNA recombination double-strand break repair via classical nonhomologous end joining double-strand break repair via nonhomologous end joining nucleotide-excision repair, DNA gap filling chromatin; DNA ligase IV complex; nucleolus; nucleus ATP binding DNA bind... |
calcium ion transmembrane transport cell volume homeostasis intracellular calcium ion homeostasis | endoplasmic reticulum; endoplasmic reticulum membrane; membrane; perinuclear endoplasmic reticulum | calcium channel activity calcium ion binding stretch-activated, monoatomic cation-selective, calcium channel activity | Schizosaccharomyces pombe | Calcium Calcium channel Calcium transport Endoplasmic reticulum Ion channel Ion transport Membrane Phosphoprotein Reference proteome Stress response Transmembrane Transmembrane helix Transport | MSSPTSPTSS | MSSPTSPTSSPGRHHWSNSKDGMPPEYTNQDPNSDQADNENSDAKAHQPQHSPQHSTENQGHTGTSDTSSLEMELSKLHPESKQRQLPHSPEHERSRSPIASVVSYRSHMTLEDENQIFNAEMAVRGSQSLQRRPTGRSVRGSMRRLSSHRSKSMRTSKSKKSGDYERTAENEEAAQEAENHLDNFGVVTFGTEAPIKAPDHPVTIFGRIFKFIQQRSFYLRSLIYIIPLGVLLLIPVFIGRFYHPQPPYRDELGHEYERHLHVGGVDLMWMAIWWEIIWLSIWAARYAAKVIPYFFAFFVSFISNNVTKWRCMAVALEF... | calcium ion transmembrane transport cell volume homeostasis intracellular calcium ion homeostasis endoplasmic reticulum; endoplasmic reticulum membrane; membrane; perinuclear endoplasmic reticulum calcium channel activity calcium ion binding stretch-activated, monoatomic cation-selective, calcium channel activity Schiz... |
exocyst localization exocytosis intracellular protein transport vesicle tethering involved in exocytosis | cell cortex of cell tip; cell cortex of growing cell tip; cell division site; cell tip; cortical dynamic polarity patch; exocyst; lateral cell cortex; nucleus; spindle pole | SNARE binding | Schizosaccharomyces pombe | Cytoplasm Cytoskeleton Exocytosis Nucleus Protein transport Reference proteome Transport | MTAAASDDAV | MTAAASDDAVYNKVADILRQCEDFHRLSTHIERFEREQASLNMHVKTELEKHVEAVELGKLALHDAQTKRVKLLQELHNMLTLCESAREMVDEFPLISRMSRIYKNCYATKQMISQLNNLVKETDVIEDMLREDLELDSDMPNLLRAHYKLSKLREFREEALYQASLEGQSDLPITLENSFSNLNTLSDNFDRLVLNFCRNIFQLVKSGHIKTIVQIFKIVEAEESSDEVLKSIRDAKSSLPDSQDGPFLSLQGMTRQLRNFRLRVLEEFQGAAAENFQRAWVSYLEDGSGELNLDFIFEDLKVAFYVLPDLTPPSYNIA... | exocyst localization exocytosis intracellular protein transport vesicle tethering involved in exocytosis cell cortex of cell tip; cell cortex of growing cell tip; cell division site; cell tip; cortical dynamic polarity patch; exocyst; lateral cell cortex; nucleus; spindle pole SNARE binding Schizosaccharomyces pombe C... |
diacylglycerol metabolic process glycerol metabolic process lipid droplet formation lipid storage triglyceride biosynthetic process | cortical endoplasmic reticulum; cytoplasm; endoplasmic reticulum; endoplasmic reticulum membrane; lipid droplet; perinuclear endoplasmic reticulum | 2-acylglycerol O-acyltransferase activity diacylglycerol O-acyltransferase activity | Schizosaccharomyces pombe | Acyltransferase Endoplasmic reticulum Glycerol metabolism Lipid biosynthesis Lipid droplet Lipid metabolism Membrane Reference proteome Transferase Transmembrane Transmembrane helix | MSEETSIPGI | MSEETSIPGIIASTPPISKDSRRNVSHWLQALAVFLHSVSLTLTASWYTVLWAFLPFWPFLIVYLIWLIYDDGFVTGKDRQKRWLRNAPPYRWFCHYFPIRLHKTTELDSEKNYIFGYHPHGIISLGAFGGFASEGADFSKLFPGINVSVLTLNSNFYVPVYRDYLMALNINSVSKKSCVSILSRKPGDSVLIVIGGAQESLLSRPGQNNLVLKKRFGFVKLAFLTGSSLVPCFAFGESDIFEQVDNNPRTRIYKFQEIVKKIAGFTVPFFYGRGLLNKTFGLMPWRKPINIVVGEPIDVPKKSHPTNQEIYEVHEEYIR... | diacylglycerol metabolic process glycerol metabolic process lipid droplet formation lipid storage triglyceride biosynthetic process cortical endoplasmic reticulum; cytoplasm; endoplasmic reticulum; endoplasmic reticulum membrane; lipid droplet; perinuclear endoplasmic reticulum 2-acylglycerol O-acyltransferase activity... |
cell cycle endocytic recycling exocytosis Golgi to plasma membrane transport septum digestion after cytokinesis | cell division site; cell septum; cell tip; cytoplasm; cytosol; exocyst; nucleus; ubiquitin ligase complex | protein-macromolecule adaptor activity | Schizosaccharomyces pombe | Cell cycle Cell division Cytoplasm Nucleus Reference proteome | MKPSEAREHA | MKPSEAREHAIRKIKEYLERRHKQQFKALFGCLTINIYLKIFTLISTPDLCNCRLVCRKFQQLCDYNSIYVKKLLLMNAWDVTLSRKLYYESQDGMSQANMSSNTSKGFHLQSSDKKYADSDRPKLSSSSLLSLPDQKIPFPVDYSTVQGKQVVLTVLDCVSQRVEFARLDYIKVWRALAPIYRNLAYASNTIDPIAFSAFRTPEEQSKVLKYLIRFGNSYPYGTYRQAMQNAILDMASLFEQACLDEFELGLHSRNLDLLRKFSHVLHDFSGPNAYVSMYLAKQTDFVRSFFHFDPYSLFISNNLEEIHINWNILESVV... | cell cycle endocytic recycling exocytosis Golgi to plasma membrane transport septum digestion after cytokinesis cell division site; cell septum; cell tip; cytoplasm; cytosol; exocyst; nucleus; ubiquitin ligase complex protein-macromolecule adaptor activity Schizosaccharomyces pombe Cell cycle Cell division Cytoplasm N... |
exonucleolytic catabolism of deadenylated mRNA nuclear-transcribed mRNA poly(A) tail shortening regulatory ncRNA-mediated gene silencing | CCR4-NOT complex; CCR4-NOT core complex; cytosol; nucleus; P-body | chromatin binding manganese ion binding metal ion binding mRNA binding poly(A)-specific ribonuclease activity RNA nuclease activity zinc ion binding | Schizosaccharomyces pombe | 3D-structure Activator Cytoplasm Exonuclease Hydrolase Magnesium Manganese Metal-binding Nuclease Nucleus Phosphoprotein Reference proteome Repressor RNA-binding Transcription Transcription regulation Zinc | MTAMNSNFSY | MTAMNSNFSYPALGVDGISSQISPIRDVWSTNLQQEMNLIMSLIERYPVVSMDTEFPGVVARPLGVFKSSDDYHYQTLRANVDSLKIIQIGLALSDEEGNAPVEACTWQFNFTFNLQDDMYAPESIELLTKSGIDFKKHQEVGIEPADFAELLIGSGLVLQEEVTWITFHSGYDFAYLLKAMTQIPLPAEYEEFYKILCIYFPKNYDIKYIMKSVLNNSKGLQDIADDLQIHRIGPQHQAGSDALLTARIFFEIRSRYFDGSIDSRMLNQLYGLGSTGSVLWHNNSSTPQIQFRDLPGAHPSPTPSNAGIPTTLTNTSSA... | exonucleolytic catabolism of deadenylated mRNA nuclear-transcribed mRNA poly(A) tail shortening regulatory ncRNA-mediated gene silencing CCR4-NOT complex; CCR4-NOT core complex; cytosol; nucleus; P-body chromatin binding manganese ion binding metal ion binding mRNA binding poly(A)-specific ribonuclease activity RNA nuc... |
mismatch repair single strand break repair | cytosol; nucleus | DNA 5'-adenosine monophosphate hydrolase activity DNA-3'-diphospho-5'-guanosine diphosphatase double-stranded DNA binding double-stranded RNA binding GMP binding guanosine binding mismatched DNA binding single-strand break-containing DNA binding single-stranded DNA binding zinc ion binding | Schizosaccharomyces pombe | 3D-structure Cytoplasm DNA damage DNA repair DNA-binding Hydrolase Metal-binding Nucleus Reference proteome Zinc | MSVHKTNDAF | MSVHKTNDAFKVLMNSAKEPIVEDIPKKYRKQSFRDNLKVYIESPESYKNVIYYDDDVVLVRDMFPKSKMHLLLMTRDPHLTHVHPLEIMMKHRSLVEKLVSYVQGDLSGLIFDEARNCLSQQLTNEALCNYIKVGFHAGPSMNNLHLHIMTLDHVSPSLKNSAHYISFTSPFFVKIDTPTSNLPTRGTLTSLFQEDLKCWRCGETFGRHFTKLKAHLQEEYDDWLDKSVSM | mismatch repair single strand break repair cytosol; nucleus DNA 5'-adenosine monophosphate hydrolase activity DNA-3'-diphospho-5'-guanosine diphosphatase double-stranded DNA binding double-stranded RNA binding GMP binding guanosine binding mismatched DNA binding single-strand break-containing DNA binding single-strande... |
FMN biosynthetic process phosphorylation riboflavin biosynthetic process riboflavin metabolic process | cytosol; mitochondrial inner membrane; mitochondrion; nucleus | ATP binding riboflavin kinase activity zinc ion binding | Schizosaccharomyces pombe | 3D-structure ATP-binding Flavoprotein FMN Kinase Metal-binding Nucleotide-binding Reference proteome Transferase Zinc | MTVNLEEKRP | MTVNLEEKRPEIVGPEKVQSPYPIRFEGKVVHGFGRGSKELGIPTANISEDAIQELLRYRDSGVYFGYAMVQKRVFPMVMSVGWNPYYKNKLRSAEVHLIERQGEDFYEEIMRVIVLGYIRPELNYAGLDKLIEDIHTDIRVALNSMDRPSYSSYKKDPFFKV | FMN biosynthetic process phosphorylation riboflavin biosynthetic process riboflavin metabolic process cytosol; mitochondrial inner membrane; mitochondrion; nucleus ATP binding riboflavin kinase activity zinc ion binding Schizosaccharomyces pombe 3D-structure ATP-binding Flavoprotein FMN Kinase Metal-binding Nucleotide... |
nuclear-transcribed mRNA poly(A) tail shortening | CCR4-NOT complex; CCR4-NOT core complex; cytoplasm; cytosol; nucleus; P-body | metal ion binding poly(A)-specific ribonuclease activity RNA binding | Schizosaccharomyces pombe | Activator Cytoplasm Exonuclease Hydrolase Leucine-rich repeat Magnesium Metal-binding Nuclease Nucleus Reference proteome Repeat Repressor RNA-binding Transcription Transcription regulation | MFNPRYTQGT | MFNPRYTQGTIYPGAHPGLLTPDHQHAAILSVQNSPALENSNISEHWKQQIALATQSRSFSSPHQRAHNAAALARSGGPGFSMNYNARTGAFTGGPNAAGLSSLGGKYNTSSTTTTLTTSTTLNTSSGTTLNSTSKTTTSSVAVDDQKSKSDSKKERRDWTCLDLGGIGLRNVSTDLFKFSFLTELYINHNNLTRLPPEIGKLKNLVILDASGNSIKTIPPELGLLTELREVLLFDNMISVIPAELGTLFQLKILGIEGNPLQDVYKNQIMESGTAGLIAALRDGCPVGPPPPERGWEKLVSDDDDDVNDNVSTSVRDLT... | nuclear-transcribed mRNA poly(A) tail shortening CCR4-NOT complex; CCR4-NOT core complex; cytoplasm; cytosol; nucleus; P-body metal ion binding poly(A)-specific ribonuclease activity RNA binding Schizosaccharomyces pombe Activator Cytoplasm Exonuclease Hydrolase Leucine-rich repeat Magnesium Metal-binding Nuclease Nuc... |
7-methylguanosine mRNA capping RNA methylation | cell division site; cytosol; mRNA cap binding complex; nucleus; P-TEFb-cap methyltransferase complex | mRNA 5'-cap (guanine-N7-)-methyltransferase activity RNA binding | Schizosaccharomyces pombe | Direct protein sequencing Methyltransferase mRNA capping mRNA processing Nucleus Reference proteome RNA-binding S-adenosyl-L-methionine Transferase | MSSSNSRVHE | MSSSNSRVHEEQPPTENRRYARPTAQMNRVIEQQPRRRDYFQNNDNSGRRGYNRHENNGNAQDVVRSHYNARPDLGYKKRQFSPIIQLKRFNNWIKSVLIQKFAPHASDYPILVLDMGCGKGGDLIKWDKAGIDGYIGIDIAEVSVNQAKKRYREMHASFDALFYAGDCFSSSINELLPPDQRKFDVVSLQFCMHYAFESEEKVRVLLGNVSKCLPRGGVMIGTIPNSDVIVKHIKMLKPGEKEWGNDIYKVRFPESPPRSFRPPYGIQYYFYLEDAVTDVPEYVVPFEAFRAVAEGYNLELIWVKPFLDILNEEKNSET... | 7-methylguanosine mRNA capping RNA methylation cell division site; cytosol; mRNA cap binding complex; nucleus; P-TEFb-cap methyltransferase complex mRNA 5'-cap (guanine-N7-)-methyltransferase activity RNA binding Schizosaccharomyces pombe Direct protein sequencing Methyltransferase mRNA capping mRNA processing Nucleus... |
cell redox homeostasis cellular detoxification of hydrogen peroxide hydrogen peroxide catabolic process negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II response to oxidative stress | cytoplasm; cytosol; nucleus | peroxidase activity peroxiredoxin activity thioredoxin peroxidase activity thioredoxin-dependent peroxiredoxin activity unfolded protein binding | Schizosaccharomyces pombe | Antioxidant Cytoplasm Disulfide bond Nucleus Oxidoreductase Peroxidase Phosphoprotein Redox-active center Reference proteome | MSLQIGKPAP | MSLQIGKPAPDFKGTAVVNGAFEEIKLADYKGKWVFLGFYPLDFTFVCPTEIVAFSEAASKFAERNAQVILTSTDSEYSHLAFINTPRKEGGLGGINIPLLADPSHKVSRDYGVLIEDAGVAFRGLFLIDPKGVLRQITINDLPVGRSVDEALRLLDAFQFVEEHGEVCPANWHKGSDTIDTKNPEKYFSKH | cell redox homeostasis cellular detoxification of hydrogen peroxide hydrogen peroxide catabolic process negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II response to oxidative stress cytoplasm; cytosol; nucleus peroxidase activity peroxiredoxin activity ... |
CENP-A containing chromatin assembly establishment of mitotic spindle orientation meiotic telomere clustering microtubule organizing center organization nuclear migration pericentric heterochromatin formation regulatory ncRNA-mediated heterochromatin formation silent mating-type cassette heterochromatin formation subte... | chromatin; chromosome, telomeric region; CLRC complex; cytoplasmic microtubule; cytosol; kinetochore; mating-type region heterochromatin; microtubule associated complex; nuclear envelope; nucleus; pericentric heterochromatin | dynein complex binding microtubule plus-end binding | Schizosaccharomyces pombe | 3D-structure Chromatin regulator Chromosome Cytoplasm Direct protein sequencing Nucleus Reference proteome Repeat Transcription Transcription regulation WD repeat | MTNSSPRVKR | MTNSSPRVKRRTDTQYLHSVSSKLPKVDFDTNNEEFFEEEFEIYDPFYRAELPCPKPSLSISKHSIAKVPSNVNKRLELQLLLTSGTFLPNSRPYLSERVRKHTHLLSNSITGDDKPSLIHVDFTPEECFILQEAKLKFGPVNSVQFNDAYSTHISPKLPGRAYEDCQKFEIDNPSLSPVDKHGAIILRTYKKNKKLLPDYLKSFYNAGSSYFQREQVHQLMDGESVFFLKPWKHFNETSGDTVCVAYNPLCEKFALGSTAQDGAYNRLGNLWIGDFHSETIQSLESHYKLNQVGEKEYSTISDLCFSKGNLFLYTGAFD... | CENP-A containing chromatin assembly establishment of mitotic spindle orientation meiotic telomere clustering microtubule organizing center organization nuclear migration pericentric heterochromatin formation regulatory ncRNA-mediated heterochromatin formation silent mating-type cassette heterochromatin formation subte... |
3'-UTR-mediated mRNA destabilization 3'-UTR-mediated mRNA stabilization negative regulation of cell wall integrity MAPK cascade negative regulation of p38MAPK cascade | cytoplasm; cytosol; nucleus | mRNA 3'-UTR AU-rich region binding mRNA 3'-UTR binding mRNA binding | Schizosaccharomyces pombe | Cytoplasm Phosphoprotein Reference proteome Repeat RNA-binding | MAYNHFSIPK | MAYNHFSIPKNIEEKENSFFDVTFQDEPDETTSTATGIAKVSIPTPKPSTPLSTLTNGSTIQQSMTNQPEPTSQVPPISAKPPMDDATYATQQLTLRALLSTREAGIIIGKAGKNVAELRSTTNVKAGVTKAVPNVHDRVLTISGPLENVVRAYRFIIDIFAKNSTNPDGTPSDANTPRKLRLLIAHSLMGSIIGRNGLRIKLIQDKCSCRMIASKDMLPQSTERTVEIHGTVDNLHAAIWEIGKCLIDDWERGAGTVFYNPVSRLTQPLPSLASTASPQQVSPPAAPSTTSGEAIPENFVSYGAQVFPATQMPFLQQPK... | 3'-UTR-mediated mRNA destabilization 3'-UTR-mediated mRNA stabilization negative regulation of cell wall integrity MAPK cascade negative regulation of p38MAPK cascade cytoplasm; cytosol; nucleus mRNA 3'-UTR AU-rich region binding mRNA 3'-UTR binding mRNA binding Schizosaccharomyces pombe Cytoplasm Phosphoprotein Refer... |
proteolysis SREBP signaling pathway | Golgi apparatus; Golgi membrane | serine-type endopeptidase activity | Schizosaccharomyces pombe | Golgi apparatus Hydrolase Membrane Protease Reference proteome Serine protease Transmembrane Transmembrane helix | MIFMILGRSK | MIFMILGRSKEFILKLPIWTQIITYIAILVYALSFFGISTGVLSLSWIGLLQKRQLYEIITYVTLHLSMLHIVFNFVSLLPAMSQFEKKQGTLACILVTVIPYTLFPGIMHLIVYHFFLRKDYVSIAGLSGWAFAFISASCVHSPQRLISFFNLFSIPAYCFPIIYLIMTTILVPKASFIGHASGAVMGYCTPFMLGSIPLKSWAQNVDPIFQSWVKNYHSFDQLSHAQLPIAEPLSTFSSFPGKGTRLGG | proteolysis SREBP signaling pathway Golgi apparatus; Golgi membrane serine-type endopeptidase activity Schizosaccharomyces pombe Golgi apparatus Hydrolase Membrane Protease Reference proteome Serine protease Transmembrane Transmembrane helix MIFMILGRSK MIFMILGRSKEFILKLPIWTQIITYIAILVYALSFFGISTGVLSLSWIGLLQKRQLYEIITYVTLH... |
DNA damage response DNA replication error-free translesion synthesis error-prone translesion synthesis meiotic cell cycle translesion synthesis | chromatin; cytosol; nucleus | damaged DNA binding DNA-directed DNA polymerase activity metal ion binding | Schizosaccharomyces pombe | Coiled coil Cytoplasm DNA damage DNA repair DNA replication DNA synthesis DNA-binding DNA-directed DNA polymerase Magnesium Meiosis Metal-binding Nucleotidyltransferase Nucleus Reference proteome Transferase Zinc Zinc-finger | MENAKDFIGE | MENAKDFIGETIKENGLLTIEDDGSSSSDEEATLKRRLAGPSVLKSGQENVNQKKINEIIYEASKGSKFFEAEQKRDRELRLRIEKVQVEVEKYQSKLRFDKAFQREWTIRQESVDTTVEDFRAKRDLTQIIVHVDCDAFYASIEELKNPKLKSLPMAVGKSVLCTANYVARKFGVRSAMPEFIARKICPDLVVIPLNLSEYAIKSKEIQNVLAQYDSNLCPASIDEFYMNLTSHLRLQELAFTVENITMVVEKIRKQVHEETGVTVSCGIAANKLLAKIASNKRKPNNQFFIPFDEIGISKFMNDLPVREVSGIGRVLE... | DNA damage response DNA replication error-free translesion synthesis error-prone translesion synthesis meiotic cell cycle translesion synthesis chromatin; cytosol; nucleus damaged DNA binding DNA-directed DNA polymerase activity metal ion binding Schizosaccharomyces pombe Coiled coil Cytoplasm DNA damage DNA repair DN... |
cell adhesion positive regulation of transcription by RNA polymerase II regulation of lipid metabolic process | chromatin; cytosol; nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specif... | Schizosaccharomyces pombe | Cell adhesion Cytoplasm DNA-binding Nucleus Reference proteome Transcription Transcription regulation | MGDYFAWDFA | MGDYFAWDFANISGSNTSGSLNLNQLNLDNINNGLHNQEDGAGGRNENSERVGSGSPGSVSMQVLSLFSAVNSALATLEKSEEFPSVVKDEQSIFPAVAKASNSLDELAQNIIPAPSPPGFNRKRKTFDEDSSVEMIRRAISDHLDLLNNCCIGIANLNEDSVHKISLTRSGKPSQLVTVSCRHSSVIQKSYGSEKRYLCPPPMVYINGNYSSIFNQSFRTEISIMNDFGQCSQPISEEYTGQGCMIFRSLHISSLVAAKSKNLRLSLDMFSNVNNQLLSHLVTSSISIVSKPSKKGSKLKISNITLRSGSVVSLYNRIN... | cell adhesion positive regulation of transcription by RNA polymerase II regulation of lipid metabolic process chromatin; cytosol; nucleus DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specif... |
chromosome segregation co-transcriptional gene silencing by RNA interference machinery negative regulation of G0 to G1 transition pericentric heterochromatin formation priRNA 3'-end processing regulatory ncRNA-mediated heterochromatin formation siRNA 3'-end processing siRNA-dependent pericentric heterochromatin formati... | ARC complex; chromosome, subtelomeric region; cytosol; heterochromatin island; mating-type region heterochromatin; pericentric heterochromatin; RITS complex | protein-macromolecule adaptor activity RNA binding RNA endonuclease activity RNA endonuclease activity, producing 5'-phosphomonoesters single-stranded RNA binding | Schizosaccharomyces pombe | Cell cycle Centromere Chromosome Chromosome partition Cytoplasm Nucleus Reference proteome RNA-mediated gene silencing Telomere | MSYKPSSEIA | MSYKPSSEIALRPGYGGLGKQITLKANFFQIISLPNETINQYHVIVGDGSRVPRKQSQLIWNSKEVKQYFGSSWMNSVYDGRSMCWSKGDIADGTIKVNIGSESHPREIEFSIQKSSKINLHTLSQFVNSKYSSDPQVLSSIMFLDLLLKKKPSETLFGFMHSFFTGENGVSLGGGVEAWKGFYQSIRPNQGFMSVNVDISSSAFWRNDSLLQILMEYTDCSNVRDLTRFDLKRLSRKFRFLKVTCQHRNNVGTDLANRVYSIEGFSSKSASDSFFVRRLNGEEQKISVAEYFLENHNVRLQYPNLPCILVKNGAMLPIE... | chromosome segregation co-transcriptional gene silencing by RNA interference machinery negative regulation of G0 to G1 transition pericentric heterochromatin formation priRNA 3'-end processing regulatory ncRNA-mediated heterochromatin formation siRNA 3'-end processing siRNA-dependent pericentric heterochromatin formati... |
lncRNA catabolic process mRNA destabilization nuclear mRNA surveillance of mRNA 3'-end processing nuclear mRNA surveillance of spliceosomal pre-mRNA splicing nuclear ncRNA surveillance nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts regulation of termination of RNA polymerase II transcription, ... | chromatin; cytoplasm; heterochromatin island; Mei2 nuclear dot complex; nuclear exosome focus; nucleus | CCR4-NOT complex binding DNA binding lncRNA binding mRNA binding N6-methyladenosine-containing RNA reader activity pre-mRNA binding pre-mRNA intronic binding protein-RNA adaptor activity RNA binding | Schizosaccharomyces pombe | 3D-structure Nucleus Phosphoprotein Reference proteome RNA-binding | MSNTNFSTSR | MSNTNFSTSRSSKSIPELPNLEALRSLWPPPSLNESGDTRSVWTTHTGEPVASSVLSTSGSNNFSSPLKRPAPESHDAPIGRRLMVDDPRLIKHGKYDFSRHCTDYGHSYEWPYFRSLRRESMLYHTSGSYPESQPPYSSYSTDAPHYYHAGSESSAYYDSRSRLHGIQPPPKRRTLSPPPRRLADPVVVGSSRYVEEEVYRRPPYTLASEVPSSASAYQAGYSSYPVRSSPQLSHEDTRHGIASSGSTRYPFVPANTRASHSPSLLEPYAHSLPSSVAPVGAYPEKSSYLLSNSSNDSASRKEKPKARASTPPPLNFSR... | lncRNA catabolic process mRNA destabilization nuclear mRNA surveillance of mRNA 3'-end processing nuclear mRNA surveillance of spliceosomal pre-mRNA splicing nuclear ncRNA surveillance nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts regulation of termination of RNA polymerase II transcription, ... |
mRNA 5'-splice site recognition mRNA splicing, via spliceosome spliceosomal snRNP assembly | catalytic step 2 spliceosome; cytosol; nucleus; post-mRNA release spliceosomal complex; precatalytic spliceosome; SMN-Sm protein complex; spliceosomal tri-snRNP complex; U1 snRNP; U2 snRNP; U2-type prespliceosome; U4 snRNP; U4/U6 x U5 tri-snRNP complex; U5 snRNP | RNA binding | Schizosaccharomyces pombe | 3D-structure Cytoplasm mRNA processing mRNA splicing Nucleus Reference proteome Ribonucleoprotein RNA-binding Spliceosome | MSKAGAPDLK | MSKAGAPDLKKYLDRQVFVQLNGSRKVYGVLRGYDIFLNIVLEDSIEEKVDGEKVKIGSVAIRGNSVIMIETLDKMT | mRNA 5'-splice site recognition mRNA splicing, via spliceosome spliceosomal snRNP assembly catalytic step 2 spliceosome; cytosol; nucleus; post-mRNA release spliceosomal complex; precatalytic spliceosome; SMN-Sm protein complex; spliceosomal tri-snRNP complex; U1 snRNP; U2 snRNP; U2-type prespliceosome; U4 snRNP; U4/U6... |
DNA double-strand break processing double-strand break repair involved in meiotic recombination double-strand break repair via homologous recombination double-strand break repair via nonhomologous end joining gene conversion at mating-type locus meiotic DNA double-strand break processing mitotic DNA replication checkpo... | nucleus; site of double-strand break | bubble DNA binding DNA end binding DNA-DNA tethering activity double-strand/single-strand DNA junction binding double-stranded DNA binding endodeoxyribonuclease activator activity endonuclease activity flap-structured DNA binding identical protein binding single-stranded DNA binding Y-form DNA binding | Schizosaccharomyces pombe | 3D-structure DNA damage DNA repair DNA-binding Endonuclease Hydrolase Meiosis Nuclease Nucleus Phosphoprotein Reference proteome | MNEEEHNKSV | MNEEEHNKSVHWSIVYRQLGNLLEQYEVEIARLKSQLVLEKKLRIQVEKELESVKTKQISSSASSKVSSNTIQELDSTTDEDEIPGSDTVDEEDPSLNAPFSEKNQSVKIPPHSPTLPVQNASAFVKPISVPLGNVKEEKFLDTNPIGAESFESSDGEMHLRARSPEDMILLRETQPLAPLDINTLGVSDNRQKKGTEKKRPFEPEFLNDDVIRGNKRKALPAYECPDCQKFYELHGPVKESSVAPTWNDENRLGGGSLPNCKHQPLVQKVGRHRKLNIPKPIPNGFWESDFVD | DNA double-strand break processing double-strand break repair involved in meiotic recombination double-strand break repair via homologous recombination double-strand break repair via nonhomologous end joining gene conversion at mating-type locus meiotic DNA double-strand break processing mitotic DNA replication checkpo... |
negative regulation of mitotic cell cycle DNA replication SCF-dependent proteasomal ubiquitin-dependent protein catabolic process telomere maintenance ubiquitin-dependent protein catabolic process | mitochondrion; nucleus; ubiquitin ligase complex | ubiquitin ligase-substrate adaptor activity | Schizosaccharomyces pombe | Mitochondrion Nucleus Reference proteome Repeat TPR repeat Ubl conjugation pathway | MNNYQVKAIK | MNNYQVKAIKEKTQQYLSKRKFEDALTFITKTIEQEPNPTIDLFELRAQVYEKSGQYSQAELDAKRMIHLNARNARGYLRLGKLLQLDGFDKKADQLYTQGLRMVHKMDPLRPVLKKVSQRLNERILRTRPVLDLFRILPREVLLCILQQLNFKSIVQCMQVCKHWRDCIKKEPSLFCCLDFSCASPRSVNSRDRNVMAVARYSVYSKDNIQEVIGLEKLGILTPTKALLRSVKSLKVYKTISPLHTQSTDKLYTIWTPFSELHYFYCATPITFSIASKILSCCKKLKQVELVDLIPDLIFDSMDWDKLFNAESVPLALK... | negative regulation of mitotic cell cycle DNA replication SCF-dependent proteasomal ubiquitin-dependent protein catabolic process telomere maintenance ubiquitin-dependent protein catabolic process mitochondrion; nucleus; ubiquitin ligase complex ubiquitin ligase-substrate adaptor activity Schizosaccharomyces pombe Mit... |
DNA replication initiation DNA strand elongation involved in DNA replication DNA unwinding involved in DNA replication double-strand break repair via break-induced replication mitotic DNA replication initiation premeiotic DNA replication | chromatin; DNA replication preinitiation complex; MCM complex; MCM core complex; nuclear pre-replicative complex; nuclear replication fork; nucleus | ATP binding ATP hydrolysis activity DNA binding DNA helicase activity | Schizosaccharomyces pombe | ATP-binding Cell cycle DNA replication DNA-binding Helicase Hydrolase Nucleotide-binding Nucleus Reference proteome | MALPTIDLKI | MALPTIDLKIPEYEECQHKITDFLSHFKQEQVQDGQQNQDISMSDAGDEPFLKSKYMDILQKISNRESNVINVDLNDLYEFDPSDTQLLHNIESNAKRFVELFSQCADALMPPPTVEINYRNEVLDVIMQQRVQRNENIDPEHKGFPPELTRGYDLYFRPVTRNKKPFSVRDLRGENLGSLLTVRGIVTRTSDVKPSLTVNAYTCDRCGYEVFQEIRQKTFLPMSECPSDECKKNDAKGQLFMSTRASKFLPFQEVKIQELTNQVPIGHIPRSLTVHLYGAITRSVNPGDIVDISGIFLPTPYTGFRAMRAGLLTDTYLE... | DNA replication initiation DNA strand elongation involved in DNA replication DNA unwinding involved in DNA replication double-strand break repair via break-induced replication mitotic DNA replication initiation premeiotic DNA replication chromatin; DNA replication preinitiation complex; MCM complex; MCM core complex; n... |
establishment or maintenance of actin cytoskeleton polarity establishment or maintenance of cell polarity regulating cell shape phosphorylation positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape protein localization to medial cortex RAM/MOR signaling pathway regulation of... | actin cortical patch; cell division site; cytoplasm; cytosol; mitotic actomyosin contractile ring; mitotic spindle pole body; new mitotic spindle pole body | ATP binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity | Schizosaccharomyces pombe | ATP-binding Cytoplasm Kinase Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MENNTASSPY | MENNTASSPYTKLELVGRGSYGAVYRGICNLTKETVAIKILNLDTDEDEVSDIQKEVAVLSELKQSDVENIIKYHGSYLVGTNLWIIMDYCHGGSVRTLMEAGPISEPCISLILRETLQALKFIHHAGIIHRDIKAANILVSMSGNVKLCDFGVAAELNINRRKRITFIGTPYWMAPEVIRDGQEYNVMADIWSLGITAYEIATGSPPHAKEDPFRAVYLIAHTAPPRLNGNFSALLKEFIASCLQDVPQRRLDSSELLKSKFIKQYSRMSISELTNVVKRYDTWQAAGGIPQTLLLGEEADDGSDPDQETSDTAASDDG... | establishment or maintenance of actin cytoskeleton polarity establishment or maintenance of cell polarity regulating cell shape phosphorylation positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape protein localization to medial cortex RAM/MOR signaling pathway regulation of... |
cell surface receptor signaling pathway immune response regulation of immune response | extracellular exosome; extracellular region; plasma membrane; secretory granule membrane; side of membrane | GPI anchor binding IgG binding transmembrane signaling receptor activity | Homo sapiens | 3D-structure Cell membrane Disulfide bond Glycoprotein GPI-anchor IgG-binding protein Immunoglobulin domain Lipoprotein Membrane Receptor Reference proteome Repeat Secreted Signal | MWQLLLPTAL | MWQLLLPTALLLLVSAGMRTEDLPKAVVFLEPQWYSVLEKDSVTLKCQGAYSPEDNSTQWFHNENLISSQASSYFIDAATVNDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVFKEEDPIHLRCHSWKNTALHKVTYLQNGKDRKYFHHNSDFHIPKATLKDSGSYFCRGLVGSKNVSSETVNITITQGLAVSTISSFSPPGYQVSFCLVMVLLFAVDTGLYFSVKTNI | cell surface receptor signaling pathway immune response regulation of immune response extracellular exosome; extracellular region; plasma membrane; secretory granule membrane; side of membrane GPI anchor binding IgG binding transmembrane signaling receptor activity Homo sapiens 3D-structure Cell membrane Disulfide bond... |
adaptive immune response cell surface receptor signaling pathway cytokine-mediated signaling pathway defense response | plasma membrane | antigen binding inhibitory MHC class I receptor activity transmembrane signaling receptor activity | Homo sapiens | Adaptive immunity Alternative splicing Disulfide bond Glycoprotein Immunity Immunoglobulin domain Membrane Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix | MTPIVTVLIC | MTPIVTVLICLRLSLGPRTHVQAGTLPKPTLWAEPGSVITQGSPVTLWCQGILETQEYRLYREKKTAPWITRIPQEIVKKGQFPIPSITWEHTGRYRCFYGSHTAGWSEPSDPLELVVTGAYIKPTLSALPSPVVTSGGNVTLHCVSQVAFGSFILCKEGEDEHPQCLNSQPRTHGWSRAIFSVGPVSPSRRWSYRCYAYDSNSPHVWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPGESLTLQCVSDVSYDRFVLYKEGERDFLQLPGPQPQAGLSQANFTLGPVSRSYGGQYRCSGAYNLSSEWSAPSDPLDILIAG... | adaptive immune response cell surface receptor signaling pathway cytokine-mediated signaling pathway defense response plasma membrane antigen binding inhibitory MHC class I receptor activity transmembrane signaling receptor activity Homo sapiens Adaptive immunity Alternative splicing Disulfide bond Glycoprotein Immunit... |
adaptive immune response cell surface receptor signaling pathway defense response negative regulation of osteoclast differentiation | plasma membrane; secretory granule membrane | signaling receptor activity transmembrane signaling receptor activity | Homo sapiens | Adaptive immunity Alternative splicing Cell membrane Disulfide bond Glycoprotein Immunity Immunoglobulin domain Membrane Phosphoprotein Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix | MTPALTALLC | MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRLHKEGSPEPLDRNNPLEPKNKARFSIPSMTEHHAGRYRCHYYSSAGWSEPSDPLEMVMTGAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCYGAHNLSSEWSAPSDPLNILMAGQ... | adaptive immune response cell surface receptor signaling pathway defense response negative regulation of osteoclast differentiation plasma membrane; secretory granule membrane signaling receptor activity transmembrane signaling receptor activity Homo sapiens Adaptive immunity Alternative splicing Cell membrane Disulfid... |
adaptive immune response cell surface receptor signaling pathway defense response | plasma membrane | transmembrane signaling receptor activity | Homo sapiens | Adaptive immunity Alternative splicing Disulfide bond Glycoprotein Immunity Immunoglobulin domain Membrane Phosphoprotein Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix | MTLTLSVLIC | MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGFYAEPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALFPVGPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNLSPRWSAPSDPLDILIAGLI... | adaptive immune response cell surface receptor signaling pathway defense response plasma membrane transmembrane signaling receptor activity Homo sapiens Adaptive immunity Alternative splicing Disulfide bond Glycoprotein Immunity Immunoglobulin domain Membrane Phosphoprotein Receptor Reference proteome Repeat Signal Tra... |
intracellular iron ion homeostasis iron ion transmembrane transport iron-sulfur cluster assembly iron-sulfur cluster export from the mitochondrion negative regulation of reactive oxygen species biosynthetic process positive regulation of heme biosynthetic process positive regulation of iron-sulfur cluster assembly tran... | mitochondrial inner membrane; mitochondrion | ABC-type iron-sulfur cluster transporter activity ATP binding ATP hydrolysis activity ATPase-coupled transmembrane transporter activity heme transmembrane transporter activity identical protein binding protein homodimerization activity | Homo sapiens | 3D-structure Acetylation Alternative splicing ATP-binding Disease variant Membrane Mitochondrion Mitochondrion inner membrane Nucleotide-binding Phosphoprotein Reference proteome Transit peptide Transmembrane Transmembrane helix Transport | MALLAMHSWR | MALLAMHSWRWAAAAAAFEKRRHSAILIRPLVSVSGSGPQWRPHQLGALGTARAYQIPESLKSITWQRLGKGNSGQFLDAAKALQVWPLIEKRTCWHGHAGGGLHTDPKEGLKDVDTRKIIKAMLSYVWPKDRPDLRARVAISLGFLGGAKAMNIVVPFMFKYAVDSLNQMSGNMLNLSDAPNTVATMATAVLIGYGVSRAGAAFFNEVRNAVFGKVAQNSIRRIAKNVFLHLHNLDLGFHLSRQTGALSKAIDRGTRGISFVLSALVFNLLPIMFEVMLVSGVLYYKCGAQFALVTLGTLGTYTAFTVAVTRWRTRFRI... | intracellular iron ion homeostasis iron ion transmembrane transport iron-sulfur cluster assembly iron-sulfur cluster export from the mitochondrion negative regulation of reactive oxygen species biosynthetic process positive regulation of heme biosynthetic process positive regulation of iron-sulfur cluster assembly tran... |
bone remodeling camera-type eye development cell fate commitment melanocyte apoptotic process melanocyte differentiation negative regulation of apoptotic process negative regulation of cell migration negative regulation of transcription by RNA polymerase II osteoclast differentiation positive regulation of DNA-template... | chromatin; cytoplasm; lysosomal membrane; nucleoplasm; nucleus; protein-containing complex | chromatin binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific E-box binding protein dimerization activity RNA polymerase II cis-regulatory region se... | Homo sapiens | 3D-structure Activator Albinism Alternative splicing Coiled coil Cytoplasm Deafness Developmental protein Disease variant DNA-binding Isopeptide bond Lysosome Membrane Microphthalmia Nucleus Osteopetrosis Phosphoprotein Reference proteome Transcription Transcription regulation Ubl conjugation Waardenburg syndrome | MQSESGIVPD | MQSESGIVPDFEVGEEFHEEPKTYYELKSQPLKSSSSAEHPGASKPPISSSSMTSRILLRQQLMREQMQEQERREQQQKLQAAQFMQQRVPVSQTPAINVSVPTTLPSATQVPMEVLKVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPGSSAPNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEEILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTACIFPTESEARALAKERQKKDNHNLIE... | bone remodeling camera-type eye development cell fate commitment melanocyte apoptotic process melanocyte differentiation negative regulation of apoptotic process negative regulation of cell migration negative regulation of transcription by RNA polymerase II osteoclast differentiation positive regulation of DNA-template... |
positive regulation of delayed rectifier potassium channel activity positive regulation of gene expression positive regulation of nitric oxide biosynthetic process positive regulation of nitric oxide mediated signal transduction positive regulation of nitric-oxide synthase activity positive regulation of peptidyl-cyste... | anchoring junction; caveola; cytosol; filopodium; glutamatergic synapse; mitochondrion; nucleus; perinuclear region of cytoplasm; podosome; sarcolemma; sarcoplasmic reticulum membrane; T-tubule; Z disc | nitric-oxide synthase binding signaling adaptor activity | Homo sapiens | Alternative splicing Cell junction Cell projection Coiled coil Disease variant Phosphoprotein Reference proteome | MPSKTKYNLV | MPSKTKYNLVDDGHDLRIPLHNEDAFQHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIRYEFKAKNIKKKKVSIMVSVDGVKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQEDGESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDLDAVGKEGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQLLQQQQQQTQVAVAQVHLLKDQ... | positive regulation of delayed rectifier potassium channel activity positive regulation of gene expression positive regulation of nitric oxide biosynthetic process positive regulation of nitric oxide mediated signal transduction positive regulation of nitric-oxide synthase activity positive regulation of peptidyl-cyste... |
cell migration | cell surface; collagen-containing extracellular matrix; Golgi lumen; lysosomal lumen; membrane; microspike; plasma membrane | identical protein binding | Homo sapiens | Cell membrane Glycoprotein Heparan sulfate Membrane Phosphoprotein Proteoglycan Reference proteome Transmembrane Transmembrane helix | MKPGPPHRAG | MKPGPPHRAGAAHGAGAGAGAAAGPGARGLLLPPLLLLLLAGRAAGAQRWRSENFERPVDLEGSGDDDSFPDDELDDLYSGSGSGYFEQESGIETAMRFSPDVALAVSTTPAVLPTTNIQPVGTPFEELPSERPTLEPATSPLVVTEVPEEPSQRATTVSTTMATTAATSTGDPTVATVPATVATATPSTPAAPPFTATTAVIRTTGVRRLLPLPLTTVATARATTPEAPSPPTTAAVLDTEAPTPRLVSTATSRPRALPRPATTQEPDIPERSTLPLGTTAPGPTEVAQTPTPETFLTTIRDEPEVPVSGGPSGDFELP... | cell migration cell surface; collagen-containing extracellular matrix; Golgi lumen; lysosomal lumen; membrane; microspike; plasma membrane identical protein binding Homo sapiens Cell membrane Glycoprotein Heparan sulfate Membrane Phosphoprotein Proteoglycan Reference proteome Transmembrane Transmembrane helix MKPGPPHRA... |
clathrin coat disassembly clathrin-dependent endocytosis dephosphorylation intracellular transport regulation of clathrin coat assembly regulation of clathrin-dependent endocytosis synaptic vesicle recycling synaptic vesicle uncoating | clathrin-coated vesicle; cytoplasm; cytosol; extrinsic component of presynaptic endocytic zone membrane; intracellular membrane-bounded organelle; postsynaptic density; vesicle | clathrin binding clathrin heavy chain binding heat shock protein binding protein tyrosine phosphatase activity SH3 domain binding | Homo sapiens | Acetylation Alternative splicing Chaperone Disease variant Hydrolase Neurodegeneration Parkinson disease Parkinsonism Phosphoprotein Protein phosphatase Reference proteome Repeat SH3-binding | MKDSENKGAS | MKDSENKGASSPDMEPSYGGGLFDMVKGGAGRLFSNLKDNLKDTLKDTSSRVIQSVTSYTKGDLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFIFCNLYSTPGPAIRLLYAKRPGIGLSPSHRRYLGYMCDLLADKPYRPHFKPLTIKSITVSPIPFFNKQRNGCRPYCDVLIGETKIYSTCTDFERMKEYRVQDGKIFIPLNITVQGDVVVSMYHLRSTIGSRLQAKVTNTQI... | clathrin coat disassembly clathrin-dependent endocytosis dephosphorylation intracellular transport regulation of clathrin coat assembly regulation of clathrin-dependent endocytosis synaptic vesicle recycling synaptic vesicle uncoating clathrin-coated vesicle; cytoplasm; cytosol; extrinsic component of presynaptic endoc... |
phosphorylation proteoglycan biosynthetic process | Golgi apparatus; Golgi membrane; nucleoplasm | ATP binding kinase activity metal ion binding phosphotransferase activity, alcohol group as acceptor | Homo sapiens | ATP-binding Disulfide bond Glycoprotein Golgi apparatus Kinase Manganese Membrane Metal-binding Nucleotide-binding Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix | MKLKQRVVLL | MKLKQRVVLLAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMTGLRVELAPKLDHTLQSPWEIAAQWVVPREVYPEETPELGAVMHAMATKKIIKADVGYKGTQLKALLILEGGQKVVFKPKRYSRDHVVEGEPYAGYDRHNAEVAAFHLDRILGFHRAPLVVGRFVNLRTEIKPVATEQLLSTFLTVGNNTCFYGKCYYCRETEPACADGDIMEGSVTLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAVFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPSLD... | phosphorylation proteoglycan biosynthetic process Golgi apparatus; Golgi membrane; nucleoplasm ATP binding kinase activity metal ion binding phosphotransferase activity, alcohol group as acceptor Homo sapiens ATP-binding Disulfide bond Glycoprotein Golgi apparatus Kinase Manganese Membrane Metal-binding Nucleotide-bind... |
muscle organ development negative regulation of cell population proliferation negative regulation of JNK cascade nervous system development protein glycosylation protein O-linked glycosylation protein O-linked mannosylation regulation of protein glycosylation | cis-Golgi network; endoplasmic reticulum; extracellular space; Golgi apparatus; Golgi membrane; nucleus | phosphotransferase activity, for other substituted phosphate groups | Homo sapiens | Alternative splicing Cardiomyopathy Congenital muscular dystrophy Cytoplasm Disease variant Dystroglycanopathy Glycoprotein Golgi apparatus Limb-girdle muscular dystrophy Lissencephaly Membrane Nucleus Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix | MSRINKNVVL | MSRINKNVVLALLTLTSSAFLLFQLYYYKHYLSTKNGAGLSKSKGSRIGFDSTQWRAVKKFIMLTSNQNVPVFLIDPLILELINKNFEQVKNTSHGSTSQCKFFCVPRDFTAFALQYHLWKNEEGWFRIAENMGFQCLKIESKDPRLDGIDSLSGTEIPLHYICKLATHAIHLVVFHERSGNYLWHGHLRLKEHIDRKFVPFRKLQFGRYPGAFDRPELQQVTVDGLEVLIPKDPMHFVEEVPHSRFIECRYKEARAFFQQYLDDNTVEAVAFRKSAKELLQLAAKTLNKLGVPFWLSSGTCLGWYRQCNIIPYSKDVDL... | muscle organ development negative regulation of cell population proliferation negative regulation of JNK cascade nervous system development protein glycosylation protein O-linked glycosylation protein O-linked mannosylation regulation of protein glycosylation cis-Golgi network; endoplasmic reticulum; extracellular spac... |
cell adhesion cellular response to leukemia inhibitory factor central nervous system development proteolysis | extracellular region; glutamatergic synapse; plasma membrane; presynaptic membrane | integrin binding metalloendopeptidase activity metallopeptidase activity | Homo sapiens | Alternative splicing Cell adhesion Cell membrane Cleavage on pair of basic residues Disulfide bond EGF-like domain Glycoprotein Membrane Reference proteome Secreted Signal Transmembrane Transmembrane helix | MKPPGSSSRQ | MKPPGSSSRQPPLAGCSLAGASCGPQRGPAGSVPASAPARTPPCRLLLVLLLLPPLAASSRPRAWGAAAPSAPHWNETAEKNLGVLADEDNTLQQNSSSNISYSNAMQKEITLPSRLIYYINQDSESPYHVLDTKARHQQKHNKAVHLAQASFQIEAFGSKFILDLILNNGLLSSDYVEIHYENGKPQYSKGGEHCYYHGSIRGVKDSKVALSTCNGLHGMFEDDTFVYMIEPLELVHDEKSTGRPHIIQKTLAGQYSKQMKNLTMERGDQWPFLSELQWLKRRKRAVNPSRGIFEEMKYLELMIVNDHKTYKKHRSSHA... | cell adhesion cellular response to leukemia inhibitory factor central nervous system development proteolysis extracellular region; glutamatergic synapse; plasma membrane; presynaptic membrane integrin binding metalloendopeptidase activity metallopeptidase activity Homo sapiens Alternative splicing Cell adhesion Cell me... |
behavioral response to acetic acid induced pain behavioral response to formalin induced pain establishment of protein localization integrin-mediated signaling pathway multicellular organismal response to stress proteolysis | axon; perikaryon; plasma membrane; presynaptic membrane | integrin binding metalloendopeptidase activity metallopeptidase activity | Homo sapiens | Alternative splicing Cell membrane Cell projection Cleavage on pair of basic residues Disulfide bond EGF-like domain Glycoprotein Membrane Reference proteome Signal Synapse Transmembrane Transmembrane helix | MRLLRRWAFA | MRLLRRWAFAALLLSLLPTPGLGTQGPAGALRWGGLPQLGGPGAPEVTEPSRLVRESSGGEVRKQQLDTRVRQEPPGGPPVHLAQVSFVIPAFNSNFTLDLELNHHLLSSQYVERHFSREGTTQHSTGAGDHCYYQGKLRGNPHSFAALSTCQGLHGVFSDGNLTYIVEPQEVAGPWGAPQGPLPHLIYRTPLLPDPLGCREPGCLFAVPAQSAPPNRPRLRRKRQVRRGHPTVHSETKYVELIVINDHQLFEQMRQSVVLTSNFAKSVVNLADVIYKEQLNTRIVLVAMETWADGDKIQVQDDLLETLARLMVYRREGL... | behavioral response to acetic acid induced pain behavioral response to formalin induced pain establishment of protein localization integrin-mediated signaling pathway multicellular organismal response to stress proteolysis axon; perikaryon; plasma membrane; presynaptic membrane integrin binding metalloendopeptidase act... |
DNA-templated transcription granulocyte differentiation negative regulation of cell population proliferation negative regulation of DNA-templated transcription negative regulation of glycolytic process positive regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of aerobic respiration res... | Golgi membrane; nucleolus; nucleoplasm; nucleus | metal ion binding transcription corepressor activity | Homo sapiens | Alternative splicing Chromosomal rearrangement Coiled coil Differentiation Golgi apparatus Membrane Metal-binding Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation Zinc Zinc-finger | MPASRLRDRA | MPASRLRDRAASSASGSTCGSMSQTHPVLESGLLASAGCSAPRGPRKGGPAPVDRKAKASAMPDSPAEVKTQPRSTPPSMPPPPPAASQGATRPPSFTPHTHREDGPATLPHGRFHGCLKWSMVCLLMNGSSHSPTAINGAPCTPNGFSNGPATSSTASLSTQHLPPACGARQLSKLKRFLTTLQQFGSDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQTPAQYLAQHEQLLLDASASSPIDSSELLLEVNENGKRRTPDRTKENGSDRDPLHPEHLSKRPCT... | DNA-templated transcription granulocyte differentiation negative regulation of cell population proliferation negative regulation of DNA-templated transcription negative regulation of glycolytic process positive regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of aerobic respiration res... |
actin filament depolymerization actin filament fragmentation apical junction assembly cortical cytoskeleton organization establishment of planar polarity of follicular epithelium locomotion maintenance of epithelial cell apical/basal polarity neutrophil mediated immunity neutrophil migration platelet formation positive... | cell junction; cell projection; cell-cell junction; cortical actin cytoskeleton; cytosol; extracellular exosome; extracellular region; plasma membrane; podosome | actin filament binding | Homo sapiens | Acetylation Actin-binding Alternative splicing Cell junction Cell projection Cytoplasm Cytoskeleton Direct protein sequencing Disease variant Phosphoprotein Reference proteome Repeat WD repeat | MPYEIKKVFA | MPYEIKKVFASLPQVERGVSKIIGGDPKGNNFLYTNGKCVILRNIDNPALADIYTEHAHQVVVAKYAPSGFYIASGDVSGKLRIWDTTQKEHLLKYEYQPFAGKIKDIAWTEDSKRIAVVGEGREKFGAVFLWDSGSSVGEITGHNKVINSVDIKQSRPYRLATGSDDNCAAFFEGPPFKFKFTIGDHSRFVNCVRFSPDGNRFATASADGQIYIYDGKTGEKVCALGGSKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVSVNSVVSTFPMGSTVLDQQLGCLWQKDHLLSVSLSGYINYLDRNNPSKPLHVIKGHS... | actin filament depolymerization actin filament fragmentation apical junction assembly cortical cytoskeleton organization establishment of planar polarity of follicular epithelium locomotion maintenance of epithelial cell apical/basal polarity neutrophil mediated immunity neutrophil migration platelet formation positive... |
canonical Wnt signaling pathway cellular response to retinoic acid mesenchymal to epithelial transition negative regulation of cardiac muscle cell differentiation negative regulation of cell-substrate adhesion negative regulation of ectodermal cell fate specification neuron differentiation non-canonical Wnt signaling p... | intracellular membrane-bounded organelle; membrane; plasma membrane; recycling endosome membrane | frizzled binding G protein-coupled receptor activity PDZ domain binding phosphatidylinositol-4,5-bisphosphate binding Wnt receptor activity Wnt-protein binding | Homo sapiens | 3D-structure Cell membrane Developmental protein Disulfide bond Endosome G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Signal Transducer Transmembrane Transmembrane helix Ubl conjugation Wnt signaling pathway | MRDPGAAAPL | MRDPGAAAPLSSLGLCALVLALLGALSAGAGAQPYHGEKGISVPDHGFCQPISIPLCTDIAYNQTILPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLDQAIPPCRSLCERARQGCEALMNKFGFQWPERLRCENFPVHGAGEICVGQNTSDGSGGPGGGPTAYPTAPYLPDLPFTALPPGASDGRGRPAFPFSCPRQLKVPPYLGYRFLGERDCGAPCEPGRANGLMYFKEEERRFARLWVGVWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYFMVAVAHVAGFLLEDRAVCVERFS... | canonical Wnt signaling pathway cellular response to retinoic acid mesenchymal to epithelial transition negative regulation of cardiac muscle cell differentiation negative regulation of cell-substrate adhesion negative regulation of ectodermal cell fate specification neuron differentiation non-canonical Wnt signaling p... |
actin cytoskeleton organization heart development muscle structure development sarcomere organization | adherens junction; cytoskeleton; filamentous actin; perinuclear region of cytoplasm; pseudopodium; stress fiber; Z disc | actin binding cytoskeletal protein binding metal ion binding muscle alpha-actinin binding protein kinase C binding | Homo sapiens | 3D-structure Alternative splicing Cardiomyopathy Cell projection Cytoplasm Cytoskeleton Disease variant LIM domain Metal-binding Methylation Myofibrillar myopathy Phosphoprotein Reference proteome Repeat Zinc | MSYSVTLTGP | MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAPSPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDLLGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLPGGSLPIKDLAVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSSTPIEHAPVCTSQATTPLLPAS... | actin cytoskeleton organization heart development muscle structure development sarcomere organization adherens junction; cytoskeleton; filamentous actin; perinuclear region of cytoplasm; pseudopodium; stress fiber; Z disc actin binding cytoskeletal protein binding metal ion binding muscle alpha-actinin binding protein ... |
cellular response to UV innate immune response negative regulation of cytokine production negative regulation of proteasomal ubiquitin-dependent protein catabolic process negative regulation of protein ubiquitination negative regulation of viral genome replication regulation of innate immune response | cytosol; nucleolus; nucleus; PML body | mRNA binding RNA nuclease activity ubiquitin binding | Homo sapiens | 3D-structure Cytoplasm Hydrolase Immunity Innate immunity Nuclease Nucleus Phosphoprotein Reference proteome RNA-binding Ubl conjugation | MAARAVLDEF | MAARAVLDEFTAPAEKAELLEQSRGRIEGLFGVSLAVLGALGAEEPLPARIWLQLCGAQEAVHSAKEYIKGICEPELEERECYPKDMHCIFVGAESLFLKSLIQDTCADLCILDIGLLGIRGSAEAVVMARSHIQQFVKLFENKENLPSSQKESEVKREFKQFVEAHADNYTMDLLILPTSLKKELLTLTQGEENLFETGDDEVIEMRDSQQTEFTQNAATGLNISRDETVLQEEARNKAGTPVSELTKQMDTVLSSSPDVLFDPINGLTPDEEALSNERICQKRRFSDSEERHTKKQFSLENVQEGEILHDAKTLAGNV... | cellular response to UV innate immune response negative regulation of cytokine production negative regulation of proteasomal ubiquitin-dependent protein catabolic process negative regulation of protein ubiquitination negative regulation of viral genome replication regulation of innate immune response cytosol; nucleolus... |
mitochondrial translation tRNA 3'-end processing | mitochondrial matrix; mitochondrion | RNA binding tRNA binding | Homo sapiens | Mitochondrion Reference proteome Repeat tRNA processing | MDFVRLARLF | MDFVRLARLFARARPMGLFILQHLDPCRARWAGGREGLMRPMWAPFSSSSSQLPLGQERQENTGSLGSDPSHSNSTATQEEDEEEEESFGTLSDKYSSRRLFRKSAAQFHNLRFGERRDEQMEPEPKLWRGRRNTPYWYFLQCKHLIKEGKLVEALDLFERQMLKEERLQPMESNYTVLIGGCGRVGYLKKAFNLYNQMKKRDLEPSDATYTALFNVCAESPWKDSALQSALKLRQQLQAKNFELNLKTYHALLKMAAKCADLRMCLDVFKEIIHKGHVVTEETFSFLLMGCIQDKKTGFRYALQVWRLMLSLGLQPSRD... | mitochondrial translation tRNA 3'-end processing mitochondrial matrix; mitochondrion RNA binding tRNA binding Homo sapiens Mitochondrion Reference proteome Repeat tRNA processing MDFVRLARLF MDFVRLARLFARARPMGLFILQHLDPCRARWAGGREGLMRPMWAPFSSSSSQLPLGQERQENTGSLGSDPSHSNSTATQEEDEEEEESFGTLSDKYSSRRLFRKSAAQFHNLRFGERRDEQMEPEPKLWR... |
cellular response to calcium ion cellular response to growth factor stimulus ERBB2 signaling pathway positive regulation of cell migration | azurophil granule membrane; cell junction; cytoplasm; cytosol; extracellular exosome; focal adhesion; mitochondrion; nucleolus; nucleoplasm; nucleus; plasma membrane | calcium-dependent phospholipid binding calcium-dependent protein binding metal ion binding protein serine/threonine kinase activity receptor tyrosine kinase binding RNA binding | Homo sapiens | Calcium Cell junction Cell membrane Cytoplasm Direct protein sequencing Membrane Metal-binding Nucleus Phosphoprotein Reference proteome Repeat | MAAQCVTKVA | MAAQCVTKVALNVSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSKTFIIDYYFEVVQKLKFGVYDIDNKTIELSDDDFLGECECTLGQIVSSKKLTRPLVMKTGRPAGKGSITISAEEIKDNRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEVVKNNLNPVWRPFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKEASRSSPVEFECINEKKRQKKKSYKNSGVISVKQCEITVECTFLDYIMGGCQLNFTVGVDFTGSNGDPRSPDSLHYISPNGVN... | cellular response to calcium ion cellular response to growth factor stimulus ERBB2 signaling pathway positive regulation of cell migration azurophil granule membrane; cell junction; cytoplasm; cytosol; extracellular exosome; focal adhesion; mitochondrion; nucleolus; nucleoplasm; nucleus; plasma membrane calcium-depende... |
autophagosome assembly mitophagy negative regulation of cell population proliferation piecemeal microautophagy of the nucleus positive regulation of autophagy positive regulation of protein targeting to mitochondrion protein localization to phagophore assembly site regulation of protein lipidation response to mitochond... | Atg1/ULK1 kinase complex; cytoplasm; cytosol; endoplasmic reticulum membrane; mitochondrion; phagophore assembly site; phagophore assembly site membrane | protein kinase binding protein serine/threonine kinase activator activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Autophagy Cytoplasm Phosphoprotein Reference proteome | METDLNSQDR | METDLNSQDRKDLDKFIKFFALKTVQVIVQARLGEKICTRSSSSPTGSDWFNLAIKDIPEVTHEAKKALAGQLPAVGRSMCVEISLKTSEGDSMELEIWCLEMNEKCDKEIKVSYTVYNRLSLLLKSLLAITRVTPAYRLSRKQGHEYVILYRIYFGEVQLSGLGEGFQTVRVGTVGTPVGTITLSCAYRINLAFMSTRQFERTPPIMGIIIDHFVDRPYPSSSPMHPCNYRTAGEDTGVIYPSVEDSQEVCTTSFSTSPPSQLSSSRLSYQPAALGVGSADLAYPVVFAAGLNATHPHQLMVPGKEGGVPLAPNQPVHG... | autophagosome assembly mitophagy negative regulation of cell population proliferation piecemeal microautophagy of the nucleus positive regulation of autophagy positive regulation of protein targeting to mitochondrion protein localization to phagophore assembly site regulation of protein lipidation response to mitochond... |
adaptive immune response B cell activation defense response hyperosmotic response positive regulation of activated T cell proliferation regulation of cytokine production signal transduction T cell activation T cell receptor signaling pathway | external side of plasma membrane; extracellular exosome; intracellular membrane-bounded organelle; membrane; plasma membrane | identical protein binding signaling receptor binding | Homo sapiens | 3D-structure Adaptive immunity Alternative splicing B-cell activation Cell membrane Disulfide bond Glycoprotein Immunity Immunoglobulin domain Membrane Reference proteome Signal Transmembrane Transmembrane helix | MRLGSPGLLF | MRLGSPGLLFLLFSSLRADTQEKEVRAMVGSDVELSCACPEGSRFDLNDVYVYWQTSESKTVVTYHIPQNSSLENVDSRYRNRALMSPAGMLRGDFSLRLFNVTPQDEQKFHCLVLSQSLGFQEVLSVEVTLHVAANFSVPVVSAPHSPSQDELTFTCTSINGYPRPNVYWINKTDNSLLDQALQNDTVFLNMRGLYDVVSVLRIARTPSVNIGCCIENVLLQQNLTVGSQTGNDIGERDKITENPVSTGEKNAATWSILAVLCLLVVVAVAIGWVCRDRCLQHSYAGAWAVSPETELTGHV | adaptive immune response B cell activation defense response hyperosmotic response positive regulation of activated T cell proliferation regulation of cytokine production signal transduction T cell activation T cell receptor signaling pathway external side of plasma membrane; extracellular exosome; intracellular membran... |
chromatin organization positive regulation of transcription by RNA polymerase II protein ubiquitination ubiquitin-dependent protein catabolic process | HULC complex; membrane; neuron projection; nucleoplasm; nucleus; ubiquitin ligase complex | metal ion binding mRNA 3'-UTR binding protein homodimerization activity ubiquitin protein ligase activity ubiquitin protein ligase binding | Homo sapiens | 3D-structure Acetylation Alternative splicing Chromatin regulator Coiled coil Isopeptide bond Metal-binding Nucleus Phosphoprotein Reference proteome Transferase Ubl conjugation Ubl conjugation pathway Zinc Zinc-finger | MSGPGNKRAA | MSGPGNKRAAGDGGSGPPEKKLSREEKTTTTLIEPIRLGGISSTEEMDLKVLQFKNKKLAERLEQRQACEDELRERIEKLEKRQATDDATLLIVNRYWAQLDETVEALLRCHESQGELSSAPEAPGTQEGPTCDGTPLPEPGTSELRDPLLMQLRPPLSEPALAFVVALGASSSEEVELELQGRMEFSKAAVSRVVEASDRLQRRVEELCQRVYSRGDSEPLSEAAQAHTRELGRENRRLQDLATQLQEKHHRISLEYSELQDKVTSAETKVLEMETTVEDLQWDIEKLRKREQKLNKHLAEALEQLNSGYYVSGSSSGF... | chromatin organization positive regulation of transcription by RNA polymerase II protein ubiquitination ubiquitin-dependent protein catabolic process HULC complex; membrane; neuron projection; nucleoplasm; nucleus; ubiquitin ligase complex metal ion binding mRNA 3'-UTR binding protein homodimerization activity ubiquiti... |
poly(A)+ mRNA export from nucleus | nucleoplasm | metal ion binding RNA binding | Homo sapiens | Coiled coil Isopeptide bond Metal-binding mRNA transport Nucleus Phosphoprotein Reference proteome Repeat Transport Ubl conjugation Zinc Zinc-finger | MPNQGEDCYF | MPNQGEDCYFFFYSTCTKGDSCPFRHCEAAIGNETVCTLWQEGRCFRQVCRFRHMEIDKKRSEIPCYWENQPTGCQKLNCAFHHNRGRYVDGLFLPPSKTVLPTVPESPEEEVKASQLSVQQNKLSVQSNPSPQLRSVMKVESSENVPSPTHPPVVINAADDDEDDDDQFSEEGDETKTPTLQPTPEVHNGLRVTSVRKPAVNIKQGECLNFGIKTLEEIKSKKMKEKSKKQGEGSSGVSSLLLHPEPVPGPEKENVRTVVRTVTLSTKQGEEPLVRLSLTERLGKRKFSAGGDSDPPLKRSLAQRLGKKVEAPETNIDK... | poly(A)+ mRNA export from nucleus nucleoplasm metal ion binding RNA binding Homo sapiens Coiled coil Isopeptide bond Metal-binding mRNA transport Nucleus Phosphoprotein Reference proteome Repeat Transport Ubl conjugation Zinc Zinc-finger MPNQGEDCYF MPNQGEDCYFFFYSTCTKGDSCPFRHCEAAIGNETVCTLWQEGRCFRQVCRFRHMEIDKKRSEIPCYWENQ... |
cell cycle cell division endocytic recycling negative regulation of adiponectin secretion protein localization to cilium regulation of cilium assembly regulation of cytokinesis regulation of early endosome to recycling endosome transport regulation of endocytic recycling regulation of protein localization to centrosome... | centriolar satellite; centrosome; cleavage furrow; cytosol; endocytic vesicle; endocytic vesicle membrane; endosome; Golgi membrane; intercellular bridge; intracellular membrane-bounded organelle; midbody; mitochondrion; nucleoplasm; postsynaptic recycling endosome membrane; recycling endosome; recycling endosome membr... | calcium ion binding dynein light intermediate chain binding identical protein binding molecular adaptor activity protein homodimerization activity protein-containing complex binding small GTPase binding | Homo sapiens | 3D-structure Alternative splicing Calcium Cell cycle Cell division Coiled coil Cytoplasm Cytoskeleton Endosome Golgi apparatus Membrane Metal-binding Phosphoprotein Reference proteome Repeat Transport | MASAPPASPP | MASAPPASPPGSEPPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEPAPGAAADGGARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGPGPRSEAPLPELDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFSPFPAPTAGELALEQGPGSPPQPSDLSQTHPLPSEPVGSQEDGPRLRAVFDALDGDGDGFVRIEDFIQFATVYGAEQVKDLTKYLDPSGLGVISFEDFYQGITAIRNGDPDGQCYGGVASAQDEEPLACPDEFDDFVTYEANEVTDSAYMGSESTYSEC... | cell cycle cell division endocytic recycling negative regulation of adiponectin secretion protein localization to cilium regulation of cilium assembly regulation of cytokinesis regulation of early endosome to recycling endosome transport regulation of endocytic recycling regulation of protein localization to centrosome... |
cellular response to low-density lipoprotein particle stimulus cytokine-mediated signaling pathway epidermal growth factor receptor signaling pathway intracellular signal transduction negative regulation of epidermal growth factor-activated receptor activity negative regulation of inflammatory response negative regulat... | cytosol; phosphatidylinositol 3-kinase complex | 1-phosphatidylinositol-3-kinase regulator activity epidermal growth factor receptor binding receptor tyrosine kinase binding | Homo sapiens | Growth regulation Reference proteome SH2 domain Signal transduction inhibitor Ubl conjugation pathway | MDKVGKMWNN | MDKVGKMWNNFKYRCQNLFGHEGGSRSENVDMNSNRCLSVKEKNISIGDSTPQQQSSPLRENIALQLGLSPSKNSSRRNQNCATEIPQIVEISIEKDNDSCVTPGTRLARRDSYSRHAPWGGKKKHSCSTKTQSSLDADKKFGRTRSGLQRRERRYGVSSVHDMDSVSSRTVGSRSLRQRLQDTVGLCFPMRTYSKQSKPLFSNKRKIHLSELMLEKCPFPAGSDLAQKWHLIKQHTAPVSPHSTFFDTFDPSLVSTEDEEDRLRERRRLSIEEGVDPPPNAQIHTFEATAQVNPLYKLGPKLAPGMTEISGDSSAIPQA... | cellular response to low-density lipoprotein particle stimulus cytokine-mediated signaling pathway epidermal growth factor receptor signaling pathway intracellular signal transduction negative regulation of epidermal growth factor-activated receptor activity negative regulation of inflammatory response negative regulat... |
actin cytoskeleton organization | plasma membrane; platelet alpha granule membrane | actin binding protein phosphatase inhibitor activity | Homo sapiens | Actin-binding Alternative splicing Lipoprotein Membrane Myristate Phosphoprotein Protein phosphatase inhibitor Reference proteome Repeat | MDNAVDGLDK | MDNAVDGLDKASIANSDGPTAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSAVLERKISTRQSREELIRRGVLKELPDQDGDVTVNFENSNGHMIPIGEESTREENVVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGASHKGDEVPPIKKNTKAPGKQAPVPPPKPASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKF... | actin cytoskeleton organization plasma membrane; platelet alpha granule membrane actin binding protein phosphatase inhibitor activity Homo sapiens Actin-binding Alternative splicing Lipoprotein Membrane Myristate Phosphoprotein Protein phosphatase inhibitor Reference proteome Repeat MDNAVDGLDK MDNAVDGLDKASIANSDGPTAGSQT... |
extracellular matrix disassembly extracellular matrix organization proteolysis skeletal system development | collagen-containing extracellular matrix; extracellular matrix; extracellular region; extracellular space; nuclear speck | metalloendopeptidase activity metallopeptidase activity peptidase activity protease binding zinc ion binding | Homo sapiens | 3D-structure Alternative splicing Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Extracellular matrix Glycoprotein Hydrolase Metal-binding Metalloprotease Protease Reference proteome Secreted Signal Zinc Zymogen | MSQTGSHPGR | MSQTGSHPGRGLAGRWLWGAQPCLLLPIVPLSWLVWLLLLLLASLLPSARLASPLPREEEIVFPEKLNGSVLPGSGAPARLLCRLQAFGETLLLELEQDSGVQVEGLTVQYLGQAPELLGGAEPGTYLTGTINGDPESVASLHWDGGALLGVLQYRGAELHLQPLEGGTPNSAGGPGAHILRRKSPASGQGPMCNVKAPLGSPSPRPRRAKRFASLSRFVETLVVADDKMAAFHGAGLKRYLLTVMAAAAKAFKHPSIRNPVSLVVTRLVILGSGEEGPQVGPSAAQTLRSFCAWQRGLNTPEDSDPDHFDTAILFTRQD... | extracellular matrix disassembly extracellular matrix organization proteolysis skeletal system development collagen-containing extracellular matrix; extracellular matrix; extracellular region; extracellular space; nuclear speck metalloendopeptidase activity metallopeptidase activity peptidase activity protease binding ... |
chromatin organization dendrite development positive regulation of dendrite morphogenesis positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II | cytosol; kinetochore; nBAF complex; nucleoplasm; nucleus | transcription coactivator activity | Homo sapiens | Activator Alternative splicing Calcium Centromere Chromatin regulator Chromosome Kinetochore Nucleus Reference proteome Repeat Transcription Transcription regulation | MSVAFASARP | MSVAFASARPRGKGEVTQQTIQKMLDENHHLIQCILEYQSKGKTAECTQYQQILHRNLVYLATIADSNQNMQSLLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQG... | chromatin organization dendrite development positive regulation of dendrite morphogenesis positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II cytosol; kinetochore; nBAF complex; nucleoplasm; nucleus transcription coactivator activity Homo sapiens Activator Altern... |
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