Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
|---|---|---|---|---|---|---|---|
acyl-CoA metabolic process fatty acid metabolic process long-chain fatty acid metabolic process negative regulation of cardiac muscle cell apoptotic process very long-chain fatty acid metabolic process | cytosol | acyl-CoA hydrolase activity carboxylic ester hydrolase activity myristoyl-CoA hydrolase activity palmitoyl-CoA hydrolase activity | Rattus norvegicus | Cytoplasm Direct protein sequencing Fatty acid metabolism Hydrolase Lipid metabolism Phosphoprotein Reference proteome Serine esterase | MEATLSLEPA | MEATLSLEPAGRSCWDEPLSITVRGLVPEQPVTLRAALRDEKGALFRARALYRADAHGELDLARAPALGGSFTGLEPMGLIWAMEPERPFWRLVKRDVQTPFVVELEVLDGHEPDGGRLLARAVHERHFMAPGVRRVPVREGRVRATLFLPPEPGPFPGIIDLFGVGGGLLEYRASLLAGKGFAVMALAYYNYDDLPKTMETMRIEYFEEAVNYLRGHPEVKGPGIGLLGISKGGELGLAMASFLKGITAAVVINGSVAAVGNTICYKDETIPPVTILRNQVKMTKDGLKDVVDALQSPLVEQKSFIPVERSDTTFLFLV... | acyl-CoA metabolic process fatty acid metabolic process long-chain fatty acid metabolic process negative regulation of cardiac muscle cell apoptotic process very long-chain fatty acid metabolic process cytosol acyl-CoA hydrolase activity carboxylic ester hydrolase activity myristoyl-CoA hydrolase activity palmitoyl-CoA... |
collagen catabolic process extracellular matrix organization proteolysis reproduction | endoplasmic reticulum membrane; extracellular matrix; extracellular space | metalloendopeptidase activity zinc ion binding | Rattus norvegicus | 3D-structure Cleavage on pair of basic residues Disulfide bond Endoplasmic reticulum Glycoprotein Hydrolase Immunoglobulin domain Membrane Metal-binding Metalloprotease Protease Reference proteome Signal-anchor Transmembrane Transmembrane helix Zinc Zymogen | MGWRACLRPE | MGWRACLRPEASGAVQGRWLGAVLSGLCLLSALAFLEWLGSPTETAWNAAQGNVDAPDVGGSTPQVPSLLSMLVTRRRRYTLTPARLRWDHFNLTYRILSFPRNLLSPEETRRGLAAAFRMWSDVSPFSFREVAPERPSDLKIGFYPVNHTDCLVSALHHCFDGPTGELAHAFFPPHGGIHFDDSEYWVLGPTRYSWKKGVWLTDLVHVAAHEIGHALGLMHSQQDQALMHLNATLRGWKALSQDELWGLHRLYGCLDRIFVCTSWARKGFCDVRQRLMKRLCPRSCDFCYEFPFPTVATTTSPTRTKTRFVREGRNMTF... | collagen catabolic process extracellular matrix organization proteolysis reproduction endoplasmic reticulum membrane; extracellular matrix; extracellular space metalloendopeptidase activity zinc ion binding Rattus norvegicus 3D-structure Cleavage on pair of basic residues Disulfide bond Endoplasmic reticulum Glycoprote... |
animal organ morphogenesis cytokine-mediated signaling pathway determination of dorsal identity embryonic body morphogenesis negative regulation of BMP signaling pathway regulation of cytokine activity sequestering of BMP from receptor via BMP binding | extracellular space | BMP binding cytokine activity heparin binding identical protein binding receptor ligand activity | Mus musculus | 3D-structure Cytokine Developmental protein Disulfide bond Glycoprotein Heparin-binding Reference proteome Secreted Signal | MFWKLSLTLL | MFWKLSLTLLLVAVLVKVAETRKNRPAGAIPSPYKDGSSNNSERWHHQIKEVLASSQEALVVTERKYLKSDWCKTQPLRQTVSEEGCRSRTILNRFCYGQCNSFYIPRHVKKEEDSFQSCAFCKPQRVTSVIVELECPGLDPPFRIKKIQKVKHCRCMSVNLSDSDKQ | animal organ morphogenesis cytokine-mediated signaling pathway determination of dorsal identity embryonic body morphogenesis negative regulation of BMP signaling pathway regulation of cytokine activity sequestering of BMP from receptor via BMP binding extracellular space BMP binding cytokine activity heparin binding id... |
negative regulation of transcription by RNA polymerase II regulation of cytokine production regulation of immune system process | nucleoplasm; nucleus | DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Mus musculus | Metal-binding Nucleus Reference proteome Repeat Zinc Zinc-finger | MGSTAAPEGA | MGSTAAPEGALGYVREFTRHSSDVLSNLNELRLRGILTDVTLLVGGQPLRAHKAVLIACSGFFYSIFRGRAGLGVDVLSLPGGPEARGFAPLLDFMYTSRLRLSPATAPAVLAAATYLQMEHVVQACHRFIQASYEPLGISLRPVEVEPPRPPTVAPPGSPRRSEGHPDPPTESRSCSQGSPSPASPDPKACNWKKYKFIVLNSQTSQAGSLVGESSGQPCPQARLPSGDEACSSSSSSEEGTTPGLQSRLSLATTTARFKCGALANNSYLFTPRAQETSLPASKQANPPPGSEFFSCQNCEAVAGCSSGLELLAPGDED... | negative regulation of transcription by RNA polymerase II regulation of cytokine production regulation of immune system process nucleoplasm; nucleus DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA bindin... |
mRNA processing positive regulation of DNA-templated transcription regulation of DNA-templated transcription elongation regulation of RNA splicing RNA splicing | DBIRD complex; intracellular membrane-bounded organelle; nuclear matrix; nucleoplasm; nucleus | DNA binding RNA polymerase II complex binding zinc ion binding | Mus musculus | Acetylation Activator Alternative splicing DNA-binding Isopeptide bond Metal-binding Methylation mRNA processing mRNA splicing Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | MDFEDDYVHS | MDFEDDYVHSTCRGAYQDFNGMDRDYGPGSYGGLDRDYGHGSYGGQRSMDSYLNQSYGMDNHSGGGGGSRFGPYESYDSRSSLGGRDLYRSGYGFNEPEQTRFGGSYGGRFESSYRNSLDSFGGRNQGGSSWEAPYSRSKLRPGFMEDRGRENYSSYSSFSSPHMKPAPVGSRGRGTPAYPESTFGSRSYDAFGGPSTGRGRGRGHMGDFGSFHRPGIIVDYQNKPANVTIATARGIKRKMMQIFIKPGGAFIKKPKLAKPMDKMNLSKSPTKTDPKNEEEEKRRIEARREKQRRRREKNSEKYGDGYRMAFTCSFCKFR... | mRNA processing positive regulation of DNA-templated transcription regulation of DNA-templated transcription elongation regulation of RNA splicing RNA splicing DBIRD complex; intracellular membrane-bounded organelle; nuclear matrix; nucleoplasm; nucleus DNA binding RNA polymerase II complex binding zinc ion binding Mus... |
positive regulation of glucose import positive regulation of protein phosphorylation protein homotrimerization response to nematode | brush border membrane; collagen-containing extracellular matrix; extracellular space; membrane raft; receptor complex; side of membrane | calcium ion binding carbohydrate binding identical protein binding oligosaccharide binding | Mus musculus | Calcium Cell membrane Disulfide bond Glycoprotein GPI-anchor Lectin Lipoprotein Membrane Metal-binding Reference proteome Secreted Signal | MTQLGFLLFI | MTQLGFLLFIMVATRGCSAAEENLDTNRWGNSFFSSLPRSCKEIKQEHTKAQDGLYFLRTKNGVIYQTFCDMTTAGGGWTLVASVHENNMRGKCTVGDRWSSQQGNRADYPEGDGNWANYNTFGSAEAATSDDYKNPGYFDIQAENLGIWHVPNKSPLHNWRKSSLLRYRTFTGFLQHLGHNLFGLYKKYPVKYGEGKCWTDNGPALPVVYDFGDARKTASYYSPSGQREFTAGYVQFRVFNNERAASALCAGVRVTGCNTEHHCIGGGGFFPEGNPVQCGDFASFDWDGYGTHNGYSSSRKITEAAVLLFYR | positive regulation of glucose import positive regulation of protein phosphorylation protein homotrimerization response to nematode brush border membrane; collagen-containing extracellular matrix; extracellular space; membrane raft; receptor complex; side of membrane calcium ion binding carbohydrate binding identical p... |
cell chemotaxis digestive tract morphogenesis endoplasmic reticulum unfolded protein response inflammatory response lung goblet cell differentiation mucus secretion positive regulation of cell-substrate adhesion positive regulation of developmental growth positive regulation of epidermal growth factor receptor signalin... | endoplasmic reticulum; extracellular region; extracellular space; mitochondrion | dystroglycan binding epidermal growth factor receptor binding identical protein binding protein homodimerization activity | Mus musculus | Disulfide bond Endoplasmic reticulum Proto-oncogene Reference proteome Secreted Signal | MEKFSVSAIL | MEKFSVSAILLLVAISGTLAKDTTVKSGAKKDPKDSRPKLPQTLSRGWGDQLIWTQTYEEALYRSKTSNRPLMVIHHLDECPHSQALKKVFAEHKEIQKLAEQFVLLNLVYETTDKHLSPDGQYVPRIVFVDPSLTVRADITGRYSNRLYAYEPSDTALLYDNMKKALKLLKTEL | cell chemotaxis digestive tract morphogenesis endoplasmic reticulum unfolded protein response inflammatory response lung goblet cell differentiation mucus secretion positive regulation of cell-substrate adhesion positive regulation of developmental growth positive regulation of epidermal growth factor receptor signalin... |
adult locomotory behavior D-aspartate import across plasma membrane detection of temperature stimulus involved in sensory perception of pain inositol phosphate catabolic process L-glutamate import across plasma membrane learning negative regulation of apoptotic process negative regulation of release of sequestered calc... | axon; axon terminus; cell surface; cytoplasmic side of plasma membrane; dendrite; dendritic shaft; dendritic spine; membrane raft; neuron spine; neuronal cell body; perikaryon; plasma membrane; symmetric synapse; terminal bouton | G protein-coupled neurotensin receptor activity identical protein binding neuropeptide receptor activity protein-containing complex binding | Mus musculus | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MHLNSSVQQG | MHLNSSVQQGAPSEPGAQPFPHPQFGLETMLLALSLSNGSGNSSESILEPNSNLDVNTDIYSKVLVTAVYLALFVVGTVGNSVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLILLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGLQNRSADGQHPGGLVCTPTVDTATVKVVIQVNTFMSFLFPMLIISILNTVIANKLTVMVHQAAEQGRGVCTVGTHNSLEHSTFNMSIEPGRVQALRHGVLVLRAVVIAFVVC... | adult locomotory behavior D-aspartate import across plasma membrane detection of temperature stimulus involved in sensory perception of pain inositol phosphate catabolic process L-glutamate import across plasma membrane learning negative regulation of apoptotic process negative regulation of release of sequestered calc... |
cellular response to magnesium ion circulatory system development gene expression kidney development negative regulation of apoptotic process post-embryonic development potassium ion import across plasma membrane potassium ion transport regulation of monoatomic ion transmembrane transport renal sodium ion absorption ti... | monoatomic ion channel complex; plasma membrane | ATP binding ATP-activated inward rectifier potassium channel activity inward rectifier potassium channel activity peptide binding phosphatidylinositol-4,5-bisphosphate binding potassium ion binding | Mus musculus | Alternative splicing ATP-binding Cell membrane Glycoprotein Ion channel Ion transport Membrane Nucleotide-binding Phosphoprotein Potassium Potassium transport Reference proteome Transmembrane Transmembrane helix Transport Voltage-gated channel | MFKHLRRWFV | MFKHLRRWFVTHIFGRSRQRARLVSKDGRCNIEFGNVDAQSRFIFFVDIWTTVLDLKWRYKMTVFITAFLGSWFLFGLLWYVVAYVHKDLPEFYPPDNRTPCVENINGMTSAFLFSLETQVTIGYGFRFVTEQCATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANLRKSLLIGSHIYGKLLKTTITPEGETIILDQTNINFVVDAGNENLFFISPLTIYHIIDHNSPFFHMAAETLSQQDFELVVFLDGTVESTSATCQVRTSYIPEEVLWGYRFVPIVSKTKEGKYRV... | cellular response to magnesium ion circulatory system development gene expression kidney development negative regulation of apoptotic process post-embryonic development potassium ion import across plasma membrane potassium ion transport regulation of monoatomic ion transmembrane transport renal sodium ion absorption ti... |
clathrin coat assembly embryonic organ development endocytosis female pregnancy in utero embryonic development membrane fission negative regulation of sprouting angiogenesis Notch signaling pathway positive regulation of clathrin coat assembly | clathrin vesicle coat; clathrin-coated pit; cytosol; endosome; nucleus; plasma membrane; postsynapse; postsynaptic membrane; presynapse; presynaptic membrane; Schaffer collateral - CA1 synapse; terminal bouton | clathrin adaptor activity clathrin binding molecular sequestering activity phospholipid binding transmembrane transporter binding | Rattus norvegicus | 3D-structure Cell membrane Coated pit Cytoplasm Endocytosis Lipid-binding Membrane Methylation Nucleus Phosphoprotein Reference proteome Repeat Ubl conjugation | MSTSSLRRQM | MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEELQLQLALAMSKEEADQPPSCGPEDDVQLQLALSLSREEHDKEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFTTPAPPQASDPWGGPASVPTAVPVAAAASDPWGAPAVPPAADPWGGAAPTPASGDP... | clathrin coat assembly embryonic organ development endocytosis female pregnancy in utero embryonic development membrane fission negative regulation of sprouting angiogenesis Notch signaling pathway positive regulation of clathrin coat assembly clathrin vesicle coat; clathrin-coated pit; cytosol; endosome; nucleus; plas... |
actin cytoskeleton organization actin filament depolymerization actin filament fragmentation apical junction assembly cortical cytoskeleton organization establishment of planar polarity of follicular epithelium locomotion maintenance of epithelial cell apical/basal polarity neutrophil mediated immunity neutrophil migra... | actin cytoskeleton; cell junction; cell projection; cell-cell junction; cortical actin cytoskeleton; myelin sheath; plasma membrane; podosome | actin binding actin filament binding | Mus musculus | Acetylation Actin-binding Cell junction Cell projection Cytoplasm Cytoskeleton Direct protein sequencing Phosphoprotein Reference proteome Repeat WD repeat | MPYEIKKVFA | MPYEIKKVFASLPQVERGVSKILGGDPKGDHFLYTNGKCVILRNIDNPAIADIYTEHAHQVVVAKYAPSGFYIASGDISGKLRIWDTTQKEHLLKYEYQPFAGKIKDIAWTEDSKRIAVVGEGREKFGAVFLWDTGSSVGEITGHNKVINSVDIKQTRPYRLATGSDDNCAAFFEGPPFKFKFTIGDHSRFVNCVRFSPDGNRFATASADGQIFIYDGKTGEKVCALGESKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVNVNSVVSTFPMGSNVLDQQLGCLWQKDHLLSISLSGYINYLDKNNPSKPLRVIKGHS... | actin cytoskeleton organization actin filament depolymerization actin filament fragmentation apical junction assembly cortical cytoskeleton organization establishment of planar polarity of follicular epithelium locomotion maintenance of epithelial cell apical/basal polarity neutrophil mediated immunity neutrophil migra... |
B cell homeostasis canonical NF-kappaB signal transduction cellular response to tumor necrosis factor cortical actin cytoskeleton organization interleukin-1-mediated signaling pathway negative regulation of bicellular tight junction assembly neuron projection development peptidyl-serine phosphorylation positive regulat... | CD40 receptor complex; cytoplasm; cytoplasmic side of plasma membrane; cytosol; IkappaB kinase complex; membrane raft; nucleus | ATP binding identical protein binding IkappaB kinase activity protein heterodimerization activity protein homodimerization activity protein kinase activity protein kinase binding protein phosphatase binding protein serine kinase activity protein serine/threonine kinase activity protein-containing complex binding scaffo... | Mus musculus | ATP-binding Cytoplasm Hydroxylation Isopeptide bond Kinase Membrane Nucleotide-binding Nucleus Phosphoprotein Reference proteome S-nitrosylation Serine/threonine-protein kinase Transferase Ubl conjugation | MSWSPSLPTQ | MSWSPSLPTQTCGAWEMKERLGTGGFGNVIRWHNQATGEQIAIKQCRQELSPKNRNRWCLEIQIMRRLNHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGGDLRRYLNQFENCCGLREGAVLTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEKRLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSEVDIVVSEDLNGAVKFSSSLPFPNNLNSVLAERLEKWLQLMLMWHPRQRGTDPQYGPNGCFRALDDILNLKLVHVLNMVTG... | B cell homeostasis canonical NF-kappaB signal transduction cellular response to tumor necrosis factor cortical actin cytoskeleton organization interleukin-1-mediated signaling pathway negative regulation of bicellular tight junction assembly neuron projection development peptidyl-serine phosphorylation positive regulat... |
hibernation lipid catabolic process | extracellular region | all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity metal ion binding triglyceride lipase activity | Ictidomys tridecemlineatus | Calcium Disulfide bond Hibernation Hydrolase Lipid degradation Lipid metabolism Metal-binding Reference proteome Secreted Signal | MLLVWSLALL | MLLVWSLALLLGAVAGKEVCYDRLGCFSDDSPWSGIVERPLKVLPWSPADVNTRFLLYTNENQDNYQQITADSSRIQSSNFKTNRKTRFIIHGFIDKGEESWLANMCKKMFQVESVNCICVDWKGGSRTGYTQASQNIRIVGAEVAYFVDFLRTQLGYSPSNVHVIGHSLGSHAAGEAGRRTNGAIGRITGLDPAEPCFEGTPELVRLDPSDAQFVDAIHTDGAPIVPNLGFGMSQTVGHLDFFPNGGIEMPGCQKNILSQIVDIDGIWEGTRDFAACNHLRSYKYYTDSIVNPTGFAAFSCASYSVFSANKCFPCPSGG... | hibernation lipid catabolic process extracellular region all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity metal ion binding triglyceride lipase activity Ictidomys tridecemlineatus Calcium Disulfide bond Hibernation Hydrolase Lipid degradation Lipid metabolism Metal-binding Reference proteome S... |
bone remodeling camera-type eye development cell differentiation cell fate commitment cellular response to zinc ion starvation DNA-templated transcription melanocyte apoptotic process melanocyte differentiation negative regulation of apoptotic process negative regulation of cell migration negative regulation of transcr... | cytoplasm; lysosomal membrane; nucleus; protein-containing complex | chromatin binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific E-box binding protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA... | Rattus norvegicus | Activator Coiled coil Cytoplasm Developmental protein DNA-binding Isopeptide bond Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Ubl conjugation | MQSESGIVAD | MQSESGIVADFEVGEEFHEEPKTYYELKSQPLKSSSSAEHSGASKPPLSSSTMTSRILLRQQLMREQMQEQERREQQQKLQAAQFMQQRVAVSQTPAINVSVPTTLPSATQVPMEVLKVQTHLENPTKYHIQQAQRHQVKQYLSTTLANKHAGQVLSPPCPNQPGDHAMPPVPGSSAPNSPMAMLTLNSNCEKEAFYKFEEQSRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEEILGLMDPALQMANTLPVSGNLIDLYSNQGLPPPGLTISNSCPANLPNIKRELTACIFPTESEARALAKERQKKDNHNLIE... | bone remodeling camera-type eye development cell differentiation cell fate commitment cellular response to zinc ion starvation DNA-templated transcription melanocyte apoptotic process melanocyte differentiation negative regulation of apoptotic process negative regulation of cell migration negative regulation of transcr... |
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process negative regulation of insulin receptor signaling pathway phosphatidylinositol biosynthetic process phosphatidylinositol phosphate biosynthetic process phosphorylation positive regulation of autophagosome assembly regulation of autophagy | autophagosome; endoplasmic reticulum; intracellular organelle; plasma membrane | 1-phosphatidylinositol-4-phosphate 5-kinase activity 1-phosphatidylinositol-5-phosphate 4-kinase activity ATP binding identical protein binding | Rattus norvegicus | Acetylation ATP-binding Cytoplasm Endoplasmic reticulum Kinase Lipid metabolism Nucleotide-binding Phosphoprotein Reference proteome Transferase | MASSSVPPAT | MASSSVPPATAPAAAGGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFAIDDHDYLVSLTRSPPSETEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVENEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKVFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEGPVREEESEWDGDCNLTGPPA... | 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process negative regulation of insulin receptor signaling pathway phosphatidylinositol biosynthetic process phosphatidylinositol phosphate biosynthetic process phosphorylation positive regulation of autophagosome assembly regulation of autophagy autophagosome... |
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process autophagosome-lysosome fusion negative regulation of insulin receptor signaling pathway phosphatidylinositol metabolic process phosphatidylinositol phosphate biosynthetic process phosphorylation positive regulation of autophagosome assembly regulation... | autophagosome; endoplasmic reticulum membrane; nucleus; plasma membrane | 1-phosphatidylinositol-4-phosphate 5-kinase activity 1-phosphatidylinositol-5-phosphate 4-kinase activity ATP binding GTP binding protein homodimerization activity | Rattus norvegicus | Acetylation ATP-binding Cell membrane Cytoplasm Endoplasmic reticulum GTP-binding Kinase Lipid metabolism Membrane Nucleotide-binding Nucleus Phosphoprotein Reference proteome Transferase Ubl conjugation | MSSNCTSTTA | MSSNCTSTTAVAVAPLSASKTKTKKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQKLRVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEETEVEDRAEEEECENDGVGGGLLCSY... | 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process autophagosome-lysosome fusion negative regulation of insulin receptor signaling pathway phosphatidylinositol metabolic process phosphatidylinositol phosphate biosynthetic process phosphorylation positive regulation of autophagosome assembly regulation... |
Golgi to vacuole transport intra-Golgi vesicle-mediated transport intracellular protein transport macroautophagy regulation of protein localization to plasma membrane retrograde transport, endosome to Golgi vesicle fusion with Golgi apparatus | cytosol; early endosome membrane; endoplasmic reticulum membrane; ER to Golgi transport vesicle membrane; Golgi apparatus; intracellular membrane-bounded organelle; late endosome membrane; lysosomal membrane; membrane; neuronal cell body; perinuclear region of cytoplasm; recycling endosome; recycling endosome membrane;... | chloride channel inhibitor activity SNAP receptor activity SNARE binding | Mus musculus | 3D-structure Acetylation Coiled coil Endosome Lysosome Membrane Methylation Phosphoprotein Protein transport Reference proteome Transmembrane Transmembrane helix Transport | MAASAASSEH | MAASAASSEHFEKLHEIFRGLLEDLQGVPERLLGTAGTEEKKKLVRDFDENQQEANETLAEMEEELRYAPLTFRNPMMSKLRNYRKDLAKLHREVRSTPLTAAPGGRGDLKYGTYTLENEHLNRLQSQRALLLQGTESLNRATQSIERSHRIATETDQIGTEIIEELGEQRDQLERTKSRLVNTNENLSKSRKILRSMSRKVITNKLLLSVIILLELAILVGLVYYKFFRHH | Golgi to vacuole transport intra-Golgi vesicle-mediated transport intracellular protein transport macroautophagy regulation of protein localization to plasma membrane retrograde transport, endosome to Golgi vesicle fusion with Golgi apparatus cytosol; early endosome membrane; endoplasmic reticulum membrane; ER to Golgi... |
cytoskeleton organization filopodium assembly lamellipodium assembly microspike assembly positive regulation of JNK cascade positive regulation of JUN kinase activity regulation of cell shape | cytoplasm; cytoskeleton; filopodium; lamellipodium | actin binding actin filament binding guanyl-nucleotide exchange factor activity metal ion binding | Rattus norvegicus | Actin-binding Cell projection Cytoplasm Cytoskeleton Direct protein sequencing Guanine-nucleotide releasing factor Metal-binding Phosphoprotein Reference proteome Repeat Zinc Zinc-finger | MEESNPAPTS | MEESNPAPTSCASKGKHSKVSDLISHFEGGSVLSSYTDVQKDSTMNLNIPQTPRQHGLTSTTPQKLPSHKSPQKQEKDSDQNQGQHGCLANGVAAAQSQMECETEKEAALSPETDTQTAAASPDAHVLNGVRNETTTDSASSVTNSHDENACDSSCRTQGTDLGLPSKEGEPVIEAELQERENGLSTEGLNPLDQHHEVKETNEQKLHKIATELLLTERAYVSRLNLLDQVFYCKLLEEANRGSFPAEMVNKIFSNISSINAFHSKFLLPELEKRMQEWETTPRIGDILQKLAPFLKMYGEYVKGFDNAVELVKNMTERV... | cytoskeleton organization filopodium assembly lamellipodium assembly microspike assembly positive regulation of JNK cascade positive regulation of JUN kinase activity regulation of cell shape cytoplasm; cytoskeleton; filopodium; lamellipodium actin binding actin filament binding guanyl-nucleotide exchange factor activi... |
animal organ regeneration bile acid and bile salt transport intestinal absorption monoatomic ion transport monocarboxylic acid transport organic anion transport sodium-independent organic anion transport | basal plasma membrane; brush border membrane | bile acid transmembrane transporter activity monocarboxylic acid transmembrane transporter activity organic anion transmembrane transporter activity sodium-independent organic anion transmembrane transporter activity thyroid hormone transmembrane transporter activity | Rattus norvegicus | Cell membrane Disulfide bond Glycoprotein Ion transport Lipid transport Membrane Reference proteome Transmembrane Transmembrane helix Transport | MGETEKRVAT | MGETEKRVATHEVRCFSKIKMFLLALTWAYVSKSLSGIYMNTMLTQIERQFDIPTSIVGFINGSFEIGNLLLIIFVSYFGTKLHRPIMIGVGCVIMGLGCFLMSLPHFLMGRYEYETTISPTSNLSSNSFLCMENRSQTLKPTQDPAECIKEMKSLMWIYVLVGNIIRGIGETPIMPLGISYIEDFAKSENSPLYIGILETGKVFGPIVGLLLGSFCASIYVDTGSVNTDDLTITPTDTRWVGAWWIGFLICAGVNILSSIPFFFFPKTLPKEGLQDDVDGTNNDKEEKHREKAKEENRGITKDFLPFMKSLSCNPIYML... | animal organ regeneration bile acid and bile salt transport intestinal absorption monoatomic ion transport monocarboxylic acid transport organic anion transport sodium-independent organic anion transport basal plasma membrane; brush border membrane bile acid transmembrane transporter activity monocarboxylic acid transm... |
actin filament organization actin filament severing actin polymerization or depolymerization barbed-end actin filament capping cilium assembly nervous system development positive regulation of lamellipodium assembly positive regulation of neuron projection development regulation of diacylglycerol biosynthetic process | actin cytoskeleton; actin filament; axon; cell projection; cytoplasm; focal adhesion; lamellipodium; neuron projection | actin binding actin filament binding Arp2/3 complex binding phosphatidylinositol-4,5-bisphosphate binding | Mus musculus | Actin capping Actin-binding Calcium Cell junction Cell projection Cytoplasm Cytoskeleton Phosphoprotein Reference proteome Repeat | MSLSSAFRAV | MSLSSAFRAVSNDPRIITWRIEKMELALVPLSAHGNFYEGDCYIVLSTRRVGSLLSQNIHFWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKKGGVASGMKHVETNTYDVKRLLHVKGKRNIQATEVEMSWDSFNRGDVFLLDLGMVIIQWNGPESNSGERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPGLMTVLQDTLGRRSMIKPAVSDEIMDQQQKSSIMLYHVSDTAGQLSVTEVATRPLVQDLLNHDDCYILDQSGTKIYVWKGKGATKVEKQAAMSKALDFIKMKG... | actin filament organization actin filament severing actin polymerization or depolymerization barbed-end actin filament capping cilium assembly nervous system development positive regulation of lamellipodium assembly positive regulation of neuron projection development regulation of diacylglycerol biosynthetic process a... |
adenylate cyclase-activating G protein-coupled receptor signaling pathway angiogenesis calcium-mediated signaling cell chemotaxis cell surface receptor signaling pathway G protein-coupled receptor signaling pathway immune response inflammatory response negative regulation of angiogenesis negative regulation of endothel... | cell surface; external side of plasma membrane; plasma membrane | C-C chemokine binding C-C chemokine receptor activity C-X-C chemokine binding C-X-C chemokine receptor activity chemokine binding signaling receptor activity | Mus musculus | Angiogenesis Cell membrane Chemotaxis Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Sulfation Transducer Transmembrane Transmembrane helix | MYLEVSERQV | MYLEVSERQVLDASDFAFLLENSTSPYDYGENESDFSDSPPCPQDFSLNFDRTFLPALYSLLFLLGLLGNGAVAAVLLSQRTALSSTDTFLLHLAVADVLLVLTLPLWAVDAAVQWVFGPGLCKVAGALFNINFYAGAFLLACISFDRYLSIVHATQIYRRDPRVRVALTCIVVWGLCLLFALPDFIYLSANYDQRLNATHCQYNFPQVGRTALRVLQLVAGFLLPLLVMAYCYAHILAVLLVSRGQRRFRAMRLVVVVVAAFAVCWTPYHLVVLVDILMDVGVLARNCGRESHVDVAKSVTSGMGYMHCCLNPLLYAFV... | adenylate cyclase-activating G protein-coupled receptor signaling pathway angiogenesis calcium-mediated signaling cell chemotaxis cell surface receptor signaling pathway G protein-coupled receptor signaling pathway immune response inflammatory response negative regulation of angiogenesis negative regulation of endothel... |
anterior/posterior pattern specification bone development brain development bronchus morphogenesis central nervous system neuron differentiation dorsal/ventral neural tube patterning embryonic camera-type eye development embryonic digit morphogenesis embryonic neurocranium morphogenesis ganglion development limb develo... | 9+0 non-motile cilium; axoneme; ciliary base; cilium; extracellular region; nucleolus; nucleoplasm; nucleus; plasma membrane | enzyme binding G protein-coupled receptor binding intraciliary transport particle A binding phosphatidylinositol binding protein-containing complex binding | Mus musculus | Cell membrane Cell projection Cilium Cytoplasm Developmental protein Membrane Nucleus Reference proteome Secreted | MEAARCAPGP | MEAARCAPGPRGDSAFDDETLRLRQLKLDNQRALLEKKQRKKRLEPLMVQPNPEARLRRLKPRGSEEHTPLVDPQMPRSDVILHGIDGPAAFLKPEAQDLESKPQVLSVGSPAPEEGTEGSADGESPEETAPKPDLQEILQKHGILSSVNYDEEPDKEEDEGGNLSSPSARSEESAAASQKAASETGASGVTAQQGDAQLGEVENLEDFAYSPAPRGVTVKCKVTRDKKGMDRGLFPTYYMHLEREENRKIFLLAGRKRKKSKTSNYLVSTDPTDLSREGESYIGKLRSNLMGTKFTVYDHGVNPVKAQGLVEKAHTRQE... | anterior/posterior pattern specification bone development brain development bronchus morphogenesis central nervous system neuron differentiation dorsal/ventral neural tube patterning embryonic camera-type eye development embryonic digit morphogenesis embryonic neurocranium morphogenesis ganglion development limb develo... |
carbohydrate metabolic process central nervous system myelination central nervous system neuron axonogenesis ganglioside biosynthetic process via lactosylceramide glycosphingolipid biosynthetic process glycosylation lactosylceramide biosynthetic process neuron maturation protein glycosylation | Golgi apparatus; Golgi cisterna membrane | galactosyltransferase activity metal ion binding UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity | Rattus norvegicus | Calcium Direct protein sequencing Disulfide bond Glycoprotein Glycosyltransferase Golgi apparatus Lipid biosynthesis Lipid metabolism Magnesium Manganese Membrane Metal-binding Reference proteome Signal-anchor Sphingolipid metabolism Transferase Transmembrane Transmembrane helix | MSALKRMMRV | MSALKRMMRVSNRSLIAFIFFFSLSTSCLYFIYVAPGIANTYLFMVQARGIMLRENVKTIGHMIRLYTNKNTTLNGTDYPEGNNTSDYLVQTTTYLPQNFTYSPHLPCPEKLPYMRGFLSVNVSEISFDEVHQLFSKDSEIEPGGHWRPQDCKPRWKVAVLIPFRNRHEHLPIFFLHLIPMLQKQRLEFAFYVIEQTGTQPFNRAMLFNVGFKEAMKDRAWDCVIFHDVDHLPENDRNYYGCGEMPRHFAAKLDKYMYILPYKEFFGGVSGLTVEQFRKINGFPNAFWGWGGEDDDLWNRVHYSGYNVTRPEGDLGKYTS... | carbohydrate metabolic process central nervous system myelination central nervous system neuron axonogenesis ganglioside biosynthetic process via lactosylceramide glycosphingolipid biosynthetic process glycosylation lactosylceramide biosynthetic process neuron maturation protein glycosylation Golgi apparatus; Golgi cis... |
protein O-linked glycosylation | Golgi apparatus; Golgi membrane | carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity | Rattus norvegicus | Disulfide bond Glycoprotein Glycosyltransferase Golgi apparatus Lectin Manganese Membrane Metal-binding Phosphoprotein Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix | MNKIRKFFRG | MNKIRKFFRGSGRVLAFIFVASVIWLLFDMAALRLSFSEINTGILKEDIMRREQTGFRVEADQMTILSPSSRGMRPPRNGAGGKESFRKAENRVLKVEENVDQVQRKGKMQFLLGRGKAVSLWHRTHVQTLPVTLPMQKTQGRDSKPEVSSLHMMSKQTTVLGSEKDSFTVSRGVPLNKTAEHTETLDKKQEAPENYNLSSDTSKQASQRALNVTISVRTDRSKQQSQTVTKSSIQFASLPILKPEEVTVTKKTEAQGKDLKYEAHKARPLLKFTADVGHLKKQSTNETGLGVLPEADGAKVAPGKKLNFSESQIVIITK... | protein O-linked glycosylation Golgi apparatus; Golgi membrane carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity Rattus norvegicus Disulfide bond Glycoprotein Glycosyltransferase Golgi apparatus Lectin Manganese Membrane Metal-binding Phosphoprotein Reference proteome Signal-... |
3'-phosphoadenosine 5'-phosphosulfate biosynthetic process blood coagulation bone development hormone metabolic process phosphorylation sulfate assimilation | cytosol | adenylylsulfate kinase activity ATP binding nucleotidyltransferase activity sulfate adenylyltransferase (ATP) activity | Mus musculus | ATP-binding Disease variant Kinase Multifunctional enzyme Nucleotide-binding Nucleotidyltransferase Reference proteome Transferase | MSANFKMNHK | MSANFKMNHKRDQQKSTNVVYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTISFALEEYLVSHAIPCYSLDGDNVRHGLNKNLGFSAGDREENIRRIAEVARLFADAGLVCITSFISPFAKDRENARKIHESAGLPFFEIFVDAPLNICESRDVKGLYKRARAGEIKGFTGIDSDYEKPETPECVLKTNLSSVSDCVQQVVELLQEQNIVPHTTIKGIHELFVPENKVDQIRAEAETLPSLPITKLDLQWVQILSEGWATPLKGFMREKEYLQTLHFDTLLDGVVPRDGVINMSIPIVLPVSADDKARLEGCS... | 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process blood coagulation bone development hormone metabolic process phosphorylation sulfate assimilation cytosol adenylylsulfate kinase activity ATP binding nucleotidyltransferase activity sulfate adenylyltransferase (ATP) activity Mus musculus ATP-binding Disease var... |
antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to type II interferon chemokine-mediated signaling pathway eosinophil chemotaxis G protein-coupled receptor signaling pathway inflammatory response kill... | extracellular space | CCR chemokine receptor binding chemokine activity | Mus musculus | Chemotaxis Cytokine Disulfide bond Inflammatory response Reference proteome Secreted Signal | MATLRVPLLV | MATLRVPLLVALVLLAVAIQTSDAGPYGANVEDSICCQDYIRHPLPSRLVKEFFWTSKSCRKPGVVLITVKNRDICADPRQVWVKKLLHKLS | antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to type II interferon chemokine-mediated signaling pathway eosinophil chemotaxis G protein-coupled receptor signaling pathway inflammatory response kill... |
anatomical structure development circadian rhythm negative regulation of apoptotic process negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II positive regulation of epithelial cell differentiation regulation of cell differentiation regulation of transcription by... | nucleus | DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific double-stranded DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Rattus norvegicus | Alternative splicing Developmental protein Differentiation DNA-binding Homeobox Nucleus Paired box Reference proteome Repressor Transcription Transcription regulation | MQQDGLSSVN | MQQDGLSSVNQLGGLFVNGRPLPLDTRQQIVQLAIRGMRPCDISRSLKVSNGCVSKILGRYYRTGVLEPKGIGGSKPRLATPAVVARIAQLKDEYPALFAWEIQRQLCAEGLCTQDKAPSVSSINRVLRALQEDQRLHWTQLRSPAVLAPALPSPHSNCEAPRGPHPGTSHRNRTIFSPGQAEALEKEFQRGQYPDSVVRGKLAAATSLPEDTVRVWFSNRRAKWRRQEKLKWETQMPGASQDLMVPKDSPGIISAQQSPGSVPSAALPVLEQLNPSFCQLCWGAVPDRCSSDTTSQACLQPYWECHSLLPVASSSYMEF... | anatomical structure development circadian rhythm negative regulation of apoptotic process negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II positive regulation of epithelial cell differentiation regulation of cell differentiation regulation of transcription by... |
cell division meiotic cell cycle mitotic spindle organization protein phosphorylation regulation of cytokinesis | chromosome; chromosome passenger complex; chromosome, centromeric region; condensed chromosome; cytoplasm; kinetochore; meiotic spindle midzone; midbody; nucleus; spindle microtubule; spindle midzone; spindle pole centrosome | ATP binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity | Mus musculus | ATP-binding Cell cycle Cell division Centromere Chromosome Cytoplasm Cytoskeleton Kinase Meiosis Mitosis Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MEPSTSTRKH | MEPSTSTRKHFTINDFEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIEKEGLEHQLRREVEIQAHLQHRNILRLYNYFYDDTRIYLILEYAPGGELYKELQRHQKLDQQRTATIIQELSDALTYCHEKKVIHRDIKPENLLLGLNGEVKISDFGWSVHTPSLRRKTMCGTLDYLPPEMIAQKPYNEMVDLWCIGVLCYELLVGKPPFESSTSSETYRRIRQVDFKFPSSVPAGAQDLISKLLRYHPSERLSLAQVLKHPWVREHSRRVLPC | cell division meiotic cell cycle mitotic spindle organization protein phosphorylation regulation of cytokinesis chromosome; chromosome passenger complex; chromosome, centromeric region; condensed chromosome; cytoplasm; kinetochore; meiotic spindle midzone; midbody; nucleus; spindle microtubule; spindle midzone; spindle... |
dopamine transport dopamine uptake epinephrine transport epinephrine uptake establishment of localization in cell histamine transport histamine uptake monoamine transport monocarboxylic acid transport neurotransmitter transport norepinephrine transport norepinephrine uptake organic anion transport organic cation transp... | apical plasma membrane; basolateral plasma membrane; endomembrane system; mitochondrial membrane; neuronal cell body; nuclear outer membrane; plasma membrane; presynapse | dopamine:sodium symporter activity monoamine transmembrane transporter activity neurotransmitter transmembrane transporter activity organic anion transmembrane transporter activity organic cation transmembrane transporter activity quaternary ammonium group transmembrane transporter activity spermidine transmembrane tra... | Rattus norvegicus | Cell membrane Glycoprotein Ion transport Membrane Mitochondrion Nucleus Reference proteome Transmembrane Transmembrane helix Transport | MPTFDQALRK | MPTFDQALRKAGEFGRFQRRVFLLLCLTGVTFAFLFVGVVFLGSQPDYYWCRGPRATALAERCAWSPEEEWNLTTPELHVPAERRGQGHCHRYLLEDTNTSSELSCDPLAAFPNRSAPLVPCSGDWRYVETHSTIVSQFDLVCGNAWMLDLTQAILNLGFLAGAFTLGYAADRYGRLIVYLISCFGVGITGVVVAFAPNFSVFVIFRFLQGVFGKGAWMTCFVIVTEIVGSKQRRIVGIVIQMFFTLGIIILPGIAYFTPSWQGIQLAISLPSFLFLLYYWVVPESPRWLITRKQGEKALQILRRVAKCNGKHLSSNYSE... | dopamine transport dopamine uptake epinephrine transport epinephrine uptake establishment of localization in cell histamine transport histamine uptake monoamine transport monocarboxylic acid transport neurotransmitter transport norepinephrine transport norepinephrine uptake organic anion transport organic cation transp... |
axo-dendritic transport cell adhesion intracellular protein transport microtubule-based movement protein localization to synapse stress granule disassembly | axon; ciliary rootlet; cytoplasm; cytoplasmic vesicle; cytosol; growth cone; kinesin complex; membrane; membrane-bounded organelle; microtubule; neuron projection; neuronal cell body; vesicle | kinesin binding tubulin binding | Mus musculus | 3D-structure Calcium Cell adhesion Cell projection Coiled coil Cytoplasm Cytoplasmic vesicle Cytoskeleton Microtubule Motor protein Phosphoprotein Reference proteome Repeat TPR repeat | MYDNMSTMVY | MYDNMSTMVYIKEEKLENVTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSSMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQNVRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDSDSSKEPLDDLFPNDEDEPGQGIQHSDSSAAAARQGYEIPARLRTLHNLVIQYASQGRYEVAVPSCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKR... | axo-dendritic transport cell adhesion intracellular protein transport microtubule-based movement protein localization to synapse stress granule disassembly axon; ciliary rootlet; cytoplasm; cytoplasmic vesicle; cytosol; growth cone; kinesin complex; membrane; membrane-bounded organelle; microtubule; neuron projection; ... |
axo-dendritic transport lysosome localization microtubule-based movement | ciliary rootlet; cytoplasm; cytosol; kinesin complex; lysosomal membrane; microtubule; mitochondrion; neuron projection; nucleoplasm; plasma membrane; protein-containing complex | kinesin binding | Mus musculus | 3D-structure Coiled coil Cytoplasm Cytoskeleton Lysosome Membrane Microtubule Motor protein Phosphoprotein Reference proteome Repeat TPR repeat | MATMVLPREE | MATMVLPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLASHEAGEAEPGSQERCLLLRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKLQRSEQAVAQLEEEKQHLLFMSQIRKLDEMLPQEEKGDVPKDSLDDLFPNEDEQSPAPSPGGGDVAAQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHP... | axo-dendritic transport lysosome localization microtubule-based movement ciliary rootlet; cytoplasm; cytosol; kinesin complex; lysosomal membrane; microtubule; mitochondrion; neuron projection; nucleoplasm; plasma membrane; protein-containing complex kinesin binding Mus musculus 3D-structure Coiled coil Cytoplasm Cytos... |
behavioral fear response embryonic skeletal system development negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II neural tube closure positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of mamma... | cytoplasm; extracellular region; nucleus; RNA polymerase II transcription regulator complex | DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific metal ion binding RNA polymerase II transcription regulatory region sequence-specific DNA binding | Rattus norvegicus | Alternative splicing Developmental protein DNA-binding Metal-binding Neurogenesis Nucleus Phosphoprotein Reference proteome Secreted Transcription Transcription regulation Zinc Zinc-finger | MEDSDSAAKQ | MEDSDSAAKQLGLAEAAAVAAAAAVAAAAAAAAESEAEEPVLSRDEDSEEDADSEAERETRRVTAVAVMAAESGHMDMGTEALPSPDEAAAAAAFAEVTTVTVANVGSSADNVFTTSVANAASISGHVLSGRTALQIGDSLNTEKATLIVVHTDGSIVETTGLKGPAAPLTPGPQSPPTPLAPGQEKGGTKYNWDPSVYDSELPVRCRNISGTLYKSRLGSGGRGRCIKQGENWYSPTEFEAMAGRASSKDWKRSIRYAGRPLQCLIQDGILNPHAASCTCAACCDDMTLSGPVRLFVPYKRRKKENELPTTPVKKDSPK... | behavioral fear response embryonic skeletal system development negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II neural tube closure positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of mamma... |
calcium ion homeostasis cellular response to hypoxia decidualization embryo implantation endoplasmic reticulum unfolded protein response intracellular calcium ion homeostasis negative regulation of gene expression negative regulation of multicellular organism growth regulation of hormone biosynthetic process regulation... | endoplasmic reticulum; extracellular region; extracellular space; Golgi apparatus; perinuclear region of cytoplasm | enzyme binding heme binding hormone activity protein homodimerization activity | Mus musculus | Disulfide bond Glycoprotein Hormone Reference proteome Secreted Signal | MCAERLGQFV | MCAERLGQFVTLALVFATLDPAQGTDSTNPPEGPQDRSSQQKGRLSLQNTAEIQHCLVNAGDVGCGVFECFENNSCEIQGLHGICMTFLHNAGKFDAQGKSFIKDALRCKAHALRHKFGCISRKCPAIREMVFQLQRECYLKHDLCSAAQENVGVIVEMIHFKDLLLHEPYVDLVNLLLTCGEDVKEAVTRSVQAQCEQSWGGLCSILSFCTSNIQRPPTAAPEHQPLADRAQLSRPHHRDTDHHLTANRGAKGERGSKSHPNAHARGRTGGQSAQGPSGSSEWEDEQSEYSDIRR | calcium ion homeostasis cellular response to hypoxia decidualization embryo implantation endoplasmic reticulum unfolded protein response intracellular calcium ion homeostasis negative regulation of gene expression negative regulation of multicellular organism growth regulation of hormone biosynthetic process regulation... |
hormone metabolic process intracellular estrogen receptor signaling pathway positive regulation of transcription by RNA polymerase II regulation of growth regulation of mRNA processing regulation of transcription by RNA polymerase II | nucleus | chromatin binding RNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding | Rattus norvegicus | Acetylation DNA-binding Isopeptide bond Methylation Nucleus Phosphoprotein Reference proteome Repressor RNA-binding Transcription Transcription regulation Ubl conjugation | MAETLSGLGD | MAETLSGLGDSGAASAAAVSSAASETGTRRLSDLRVIDLRAELRKRNLTSSGNKSVLMERLKKAIEEEGGNPDEIEVISEGNKKMPKRPSKGKKPEDEGVEDNGLEENSGDGQEDVETSLENLQDMDMMDISVLDEADIDNGSVADCVEEEEEATLPEGLGLLRIGRLQSKGLPEQLQELAIDDKEAINNVDTSSSDFTILQEMEEASLEPENEKILDILGETCKSEPVKEEGSELEQPFAQATSSVGPDRKLAEEEDLFESCGHPEEEEEEEEEEEQEEEQEEEGDLALASSSKSESSSTRCQWSEADALLAVVKREPA... | hormone metabolic process intracellular estrogen receptor signaling pathway positive regulation of transcription by RNA polymerase II regulation of growth regulation of mRNA processing regulation of transcription by RNA polymerase II nucleus chromatin binding RNA binding RNA polymerase II cis-regulatory region sequence... |
cellular response to alkaline pH cellular response to fatty acid cellular response to mechanical stimulus cellular response to temperature stimulus detection of mechanical stimulus involved in sensory perception of touch memory potassium ion transmembrane transport sensory perception of pain sensory perception of tempe... | plasma membrane; potassium channel complex | identical protein binding mechanosensitived potassium channel activity outward rectifier potassium channel activity potassium channel activity potassium ion leak channel activity temperature-gated cation channel activity | Mus musculus | 3D-structure Alternative splicing Cell membrane Disulfide bond Glycoprotein Ion channel Ion transport Membrane Potassium Potassium channel Potassium transport Reference proteome Transmembrane Transmembrane helix Transport Voltage-gated channel | MRSTTLLALL | MRSTTLLALLALVLLYLVSGALVFQALEQPHEQQAQKKMDHGRDQFLRDHPCVSQKSLEDFIKLLVEALGGGANPETSWTNSSNHSSAWNLGSAFFFSGTIITTIGYGNIVLHTDAGRLFCIFYALVGIPLFGMLLAGVGDRLGSSLRRGIGHIEAIFLKWHVPPGLVRSLSAVLFLLIGCLLFVLTPTFVFSYMESWSKLEAIYFVIVTLTTVGFGDYVPGDGTGQNSPAYQPLVWFWILFGLAYFASVLTTIGNWLRAVSRRTRAEMGGLTAQAASWTGTVTARVTQRTGPSAPPPEKEQPLLPSSLPAPPAVVEPAG... | cellular response to alkaline pH cellular response to fatty acid cellular response to mechanical stimulus cellular response to temperature stimulus detection of mechanical stimulus involved in sensory perception of touch memory potassium ion transmembrane transport sensory perception of pain sensory perception of tempe... |
blood vessel development brassinosteroid biosynthetic process cholesterol biosynthetic process lung development lung epithelial cell differentiation multicellular organism growth post-embryonic development regulation of cell population proliferation regulation of cholesterol biosynthetic process sterol biosynthetic pro... | endoplasmic reticulum; endoplasmic reticulum membrane; nuclear outer membrane | 7-dehydrocholesterol reductase activity NADP binding sterol delta7 reductase activity | Mus musculus | Cholesterol biosynthesis Cholesterol metabolism Endoplasmic reticulum Lipid biosynthesis Lipid metabolism Membrane NADP Oxidoreductase Phosphoprotein Reference proteome Steroid biosynthesis Steroid metabolism Sterol biosynthesis Sterol metabolism Transmembrane Transmembrane helix | MASKSQHNAP | MASKSQHNAPKVKSPNGKAGSQGQWGRAWEVDWFSLASIIFLLLFAPFIVYYFIMACDQYSCSLTAPALDIATGHASLADIWAKTPPVTAKAAQLYALWVSFQVLLYSWLPDFCHRFLPGYVGGVQEGAITPAGVVNKYEVNGLQAWLITHILWFVNAYLLSWFSPTIIFDNWIPLLWCANILGYAVSTFAMIKGYLFPTSAEDCKFTGNFFYNYMMGIEFNPRIGKWFDFKLFFNGRPGIVAWTLINLSFAAKQQELYGHVTNSMILVNVLQAIYVLDFFWNETWYLKTIDICHDHFGWYLGWGDCVWLPYLYTLQGLY... | blood vessel development brassinosteroid biosynthetic process cholesterol biosynthetic process lung development lung epithelial cell differentiation multicellular organism growth post-embryonic development regulation of cell population proliferation regulation of cholesterol biosynthetic process sterol biosynthetic pro... |
protein catabolic process proteolysis | calpain complex; cytosol; membrane; plasma membrane | calcium ion binding calcium-dependent cysteine-type endopeptidase activity protein-containing complex binding | Mus musculus | Acetylation Calcium Cell membrane Cytoplasm Membrane Metal-binding Phosphoprotein Reference proteome Repeat | MFLVNSFLKG | MFLVNSFLKGGGGGGGGGGLGGGLGNVLGGLISGAAGGGGGGGGGMGLGGGGGGGGTAMRILGGVISAISEAAAQYNPEPPPPRSHYSNIEANESEEVRQFRKLFVQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKKWQAIYKRFDTDRSGTIGSHELPGAFEAAGFHLNEHLYSMIIRRYADESGNMDFDNFISCLVRLDAMFRAFKSLDKNGTGQIQVNIQEWLQLTMYS | protein catabolic process proteolysis calpain complex; cytosol; membrane; plasma membrane calcium ion binding calcium-dependent cysteine-type endopeptidase activity protein-containing complex binding Mus musculus Acetylation Calcium Cell membrane Cytoplasm Membrane Metal-binding Phosphoprotein Reference proteome Repeat... |
anatomical structure morphogenesis apoptotic DNA fragmentation cell differentiation embryonic eye morphogenesis extraocular skeletal muscle development female gonad development female somatic sex determination granulosa cell differentiation negative regulation of DNA-templated transcription negative regulation of gene ... | Flemming body; nucleoplasm; nucleus | cysteine-type endopeptidase regulator activity involved in apoptotic process DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific nuclear estrogen receptor binding RNA polymera... | Mus musculus | Differentiation DNA-binding Isopeptide bond Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Ubl conjugation | MMASYPEPED | MMASYPEPEDTAGTLLAPESGRAVKEAEASPPSPGKGGGTTPEKPDPAQKPPYSYVALIAMAIRESAEKRLTLSGIYQYIIAKFPFYEKNKKGWQNSIRHNLSLNECFIKVPREGGGERKGNYWTLDPACEDMFEKGNYRRRRRMKRPFRPPPAHFQPGKGLFGSGGAAGGCGVPGAGADGYGYLAPPKYLQSGFLNNSWPLPQPPSPMPYASCQMAAAAAAAAAAAAAAGPGSPGAAAVVKGLAGPAASYGPYSRVQSMALPPGVVNSYNGLGGPPAAPPPPPPPPHPHPHPHAHHLHAAAAPPPAPPHHGAAAPPPGQ... | anatomical structure morphogenesis apoptotic DNA fragmentation cell differentiation embryonic eye morphogenesis extraocular skeletal muscle development female gonad development female somatic sex determination granulosa cell differentiation negative regulation of DNA-templated transcription negative regulation of gene ... |
CRD-mediated mRNA stabilization dendrite arborization mRNA transport negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay negative regulation of translation nervous system development neuronal stem cell population maintenance pallium cell proliferation in forebrain positive r... | axon; CRD-mediated mRNA stability complex; cytoplasm; cytoplasmic stress granule; cytosol; dendrite; dendritic spine; filopodium; growth cone; lamellipodium; neuronal cell body; nucleoplasm; nucleus; P-body; perinuclear region of cytoplasm; ribonucleoprotein complex | mRNA 3'-UTR binding mRNA 5'-UTR binding mRNA binding N6-methyladenosine-containing RNA reader activity translation regulator activity | Mus musculus | 3D-structure Cell projection Cytoplasm Direct protein sequencing mRNA transport Nucleus Phosphoprotein Reference proteome Repeat RNA-binding Synapse Translation regulation Transport | MNKLYIGNLN | MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGKVELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETAVVNVTYSNREQTRQAIMKLNGHQLENHALKVSYIPDEQITQGPENGRRGGFGSRGQPRQGSPVAAGAPAKQQPVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSSACKMILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTL... | CRD-mediated mRNA stabilization dendrite arborization mRNA transport negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay negative regulation of translation nervous system development neuronal stem cell population maintenance pallium cell proliferation in forebrain positive r... |
peptidyl-threonine dephosphorylation response to starvation T-helper cell differentiation | mitochondrial matrix; mitochondrion | -phosphatase activity phosphatase regulator activity metal ion binding protein serine/threonine phosphatase activity | Rattus norvegicus | Hydrolase Magnesium Manganese Metal-binding Mitochondrion Protein phosphatase Reference proteome Transit peptide | MSSTASYRIF | MSSTASYRIFNFARNRIAVLRGGRRLYSRAATSRNQVKWRLFSPASLAVNDSSPHGGFALRKAYRHTSTEEEDFHLQLSPEQVSDLLRAGESSHKVLDFNSGVPNSVLRFESNQLAANSPVEDRQGVASCVQTRGTVFGIFDGHGGHACAQAVSERLFYYMAVSLMSHKTLEQMEEAMENMKPLLPILQWLKHPGDSIYKDITSVHLDHLRVYWQELLDLHMETGLSTEEALMYSFQRLDSDISLEIQAPLEDEVTKNLSLQVAFSGATACMAHVDGVHLHIANAGDCRAILGVQGDNGAWSCLPLTCDHNAWNEAELSR... | peptidyl-threonine dephosphorylation response to starvation T-helper cell differentiation mitochondrial matrix; mitochondrion -phosphatase activity phosphatase regulator activity metal ion binding protein serine/threonine phosphatase activity Rattus norvegicus Hydrolase Magnesium Manganese Metal-binding Mitochondrion ... |
transport along microtubule vesicle transport along microtubule | axon cytoplasm; cytoplasm; cytoplasmic dynein complex; cytoplasmic ribonucleoprotein granule; kinetochore; microtubule; nucleus; perinuclear region of cytoplasm; recycling endosome; spindle pole; vesicle | dynein heavy chain binding dynein light chain binding microtubule binding microtubule motor activity spectrin binding | Mus musculus | Acetylation Alternative splicing Centromere Chromosome Cytoplasm Cytoskeleton Dynein Kinetochore Microtubule Motor protein Phosphoprotein Reference proteome Repeat Transport WD repeat | MSDKSDLKAE | MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALLQSIGISPEPPLVPTPMSPSSKSVSTPSDAGSQDSGDLGPLTRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVEPKIGHDSELENQEKKQETKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYSNNEDAPHEPDGVALVWNMKFKKTTPEYVF... | transport along microtubule vesicle transport along microtubule axon cytoplasm; cytoplasm; cytoplasmic dynein complex; cytoplasmic ribonucleoprotein granule; kinetochore; microtubule; nucleus; perinuclear region of cytoplasm; recycling endosome; spindle pole; vesicle dynein heavy chain binding dynein light chain bindin... |
negative regulation of neuron projection development transport along microtubule | centrosome; cytoplasmic dynein complex; dynein complex; microtubule; outer dynein arm; vesicle | dynein heavy chain binding dynein light chain binding protein-containing complex binding | Mus musculus | Acetylation Cytoplasm Cytoskeleton Dynein Microtubule Motor protein Phosphoprotein Reference proteome Repeat Transport WD repeat | MSDKSDLKAE | MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKETDQKKEAAVSVQEESDLEKKRREAEALLQSMGLTTDSPIVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRRGPIKLGMAKITQVDFPPREIVTYTKETQTPVTAQPKEDEEEEDDVATPKPPVEPEEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERALSEQINIFFDYSGRDLEDKEGEIQAGAKLSLNRQFFDERWSKHRVVSCLDWSSQYPELLVASYNNNEEAPHEPDGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPN... | negative regulation of neuron projection development transport along microtubule centrosome; cytoplasmic dynein complex; dynein complex; microtubule; outer dynein arm; vesicle dynein heavy chain binding dynein light chain binding protein-containing complex binding Mus musculus Acetylation Cytoplasm Cytoskeleton Dynein ... |
G protein-coupled receptor signaling pathway | nucleoplasm; plasma membrane; postsynaptic density | G protein-coupled receptor activity melatonin receptor activity | Mus musculus | Cell membrane Disulfide bond G-protein coupled receptor Membrane Receptor Reference proteome Synapse Transducer Transmembrane Transmembrane helix | MATVPKSNMG | MATVPKSNMGPTKAVPTPFGCIGCKLPKPDYPPALIIFMFCAMVITVVVDLIGNSMVILAVTKNKKLRNSGNIFVASLSVADMLVAIYPYPLMLYAMSVGGWDLSQLQCQMVGLVTGLSVVGSIFNITAIAINRYCYICHSLQYKRIFSLRNTCIYLVVTWVMTVLAVLPNMYIGTIEYDPRTYTCIFNYVNNPAFTVTIVCIHFVLPLIIVGYCYTKIWIKVLAARDPAGQNPDNQFAEVRNFLTMFVIFLLFAVCWCPVNVLTVLVAVIPKEMAGKIPNWLYLAAYCIAYFNSCLNAIIYGILNESFRREYWTIFHAM... | G protein-coupled receptor signaling pathway nucleoplasm; plasma membrane; postsynaptic density G protein-coupled receptor activity melatonin receptor activity Mus musculus Cell membrane Disulfide bond G-protein coupled receptor Membrane Receptor Reference proteome Synapse Transducer Transmembrane Transmembrane helix M... |
lung growth response to dexamethasone response to manganese ion response to oxygen levels response to parathyroid hormone response to Thyroglobulin triiodothyronine response to vitamin D response to vitamin K vitamin K metabolic process | endoplasmic reticulum membrane | gamma-glutamyl carboxylase activity peptide binding vitamin binding | Rattus norvegicus | Acetylation Disulfide bond Endoplasmic reticulum Lyase Membrane Reference proteome Transmembrane Transmembrane helix | MAVHRGSARA | MAVHRGSARAAPASDKVQKNKPAQTSGLEQGSRMARIFGFEWADLSSWQSVVTLLNRPTDPANLAVFRFLFAFLMLLDIPQERGLSSLDRKYLDGLDVCRFPLLDALRPLPLDWMYLVYTIMFLGALGMMLGLWYRLSCMLFLLPYWYVFLLDKTSWNNHSYLYGLLAFQLTFMDANHYWSVDGLLSAQKKNAHVPLWNYTVLRGQIFIVYFIAGVKKLDADWVEGYSMEHLSRHWLFSPFKLVLSEELTSLLVVHWCGLLLDLSAGFLLFFDASRPIGLVFVSYFHCMNSQLFSIGMFPYVMLASSPLFCSAEWPRKLV... | lung growth response to dexamethasone response to manganese ion response to oxygen levels response to parathyroid hormone response to Thyroglobulin triiodothyronine response to vitamin D response to vitamin K vitamin K metabolic process endoplasmic reticulum membrane gamma-glutamyl carboxylase activity peptide binding ... |
cell volume homeostasis cellular hyperosmotic response cellular hypotonic response cellular response to chemokine cellular response to potassium ion chemokine (C-X-C motif) ligand 12 signaling pathway inflammatory response intracellular chloride ion homeostasis intracellular signal transduction macrophage activation ma... | apical plasma membrane; basolateral plasma membrane; cell body; cell cortex; cytoplasm; cytosol; membrane; nucleus | ATP binding kinase activity protein kinase activity protein kinase binding protein serine kinase activity protein serine/threonine kinase activity | Rattus norvegicus | Acetylation ATP-binding Cytoplasm Kinase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MAEPSGSPVH | MAEPSGSPVHVQLPQQAAPVTAAAAAPAAATSAPAPAPAPAAPAAPAPAPAAAPAPAPAAQAVGWPICRDAYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFR... | cell volume homeostasis cellular hyperosmotic response cellular hypotonic response cellular response to chemokine cellular response to potassium ion chemokine (C-X-C motif) ligand 12 signaling pathway inflammatory response intracellular chloride ion homeostasis intracellular signal transduction macrophage activation ma... |
brainstem development ciliary neurotrophic factor-mediated signaling pathway motor neuron apoptotic process negative regulation of motor neuron apoptotic process negative regulation of neuron apoptotic process positive regulation of cell population proliferation sex differentiation skeletal muscle organ development suc... | apical plasma membrane; ciliary neurotrophic factor receptor complex; CNTFR-CLCF1 complex; external side of plasma membrane | ciliary neurotrophic factor receptor activity cytokine binding cytokine receptor activity signaling receptor binding | Mus musculus | Cell membrane Disulfide bond Glycoprotein GPI-anchor Immunoglobulin domain Lipoprotein Membrane Receptor Reference proteome Repeat Signal | MAASVPWACC | MAASVPWACCAVLAAAAAAVYTQKHSPQEAPHVQYERLGADVTLPCGTASWDAAVTWRVNGTDLAPDLLNGSQLILRSLELGHSGLYACFHRDSWHLRHQVLLHVGLPPREPVLSCRSNTYPKGFYCSWHLPTPTYIPNTFNVTVLHGSKIMVCEKDPALKNRCHIRYMHLFSTIKYKVSISVSNALGHNTTAITFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPDPESFPLKFFLRYRPLILDQWQHVELSDGTAHTITDAYAGKEYIIQVAAKDNEIGTWSDWSVAAHATPWTEEPRHLTTEAQAPETTT... | brainstem development ciliary neurotrophic factor-mediated signaling pathway motor neuron apoptotic process negative regulation of motor neuron apoptotic process negative regulation of neuron apoptotic process positive regulation of cell population proliferation sex differentiation skeletal muscle organ development suc... |
autosome genomic imprinting C-5 methylation of cytosine cellular response to amino acid stimulus cellular response to bisphenol A cellular response to ethanol cellular response to hypoxia DNA methylation DNA methylation on cytosine DNA methylation-dependent heterochromatin formation genomic imprinting hepatocyte apopto... | catalytic complex; chromosome, centromeric region; cytoplasm; euchromatin; heterochromatin; nuclear matrix; nucleoplasm; nucleus; XY body | chromatin binding DNA (cytosine-5-)-methyltransferase activity DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates DNA binding identical protein binding metal ion binding protein-cysteine methyltransferase activity RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase I... | Mus musculus | 3D-structure Alternative promoter usage Chromatin regulator Chromosome Cytoplasm DNA-binding Isopeptide bond Metal-binding Methylation Methyltransferase Nucleus Phosphoprotein Reference proteome Repressor S-adenosyl-L-methionine Transcription Transcription regulation Transferase Ubl conjugation Zinc Zinc-finger | MPSSGPGDTS | MPSSGPGDTSSSSLEREDDRKEGEEQEENRGKEERQEPSATARKVGRPGRKRKHPPVESSDTPKDPAVTTKSQPMAQDSGPSDLLPNGDLEKRSEPQPEEGSPAAGQKGGAPAEGEGTETPPEASRAVENGCCVTKEGRGASAGEGKEQKQTNIESMKMEGSRGRLRGGLGWESSLRQRPMPRLTFQAGDPYYISKRKRDEWLARWKREAEKKAKVIAVMNAVEENQASGESQKVEEASPPAVQQPTDPASPTVATTPEPVGGDAGDKNATKAADDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEG... | autosome genomic imprinting C-5 methylation of cytosine cellular response to amino acid stimulus cellular response to bisphenol A cellular response to ethanol cellular response to hypoxia DNA methylation DNA methylation on cytosine DNA methylation-dependent heterochromatin formation genomic imprinting hepatocyte apopto... |
autosome genomic imprinting C-5 methylation of cytosine cellular response to amino acid stimulus DNA methylation DNA methylation-dependent heterochromatin formation negative regulation of DNA-templated transcription negative regulation of gene expression, epigenetic negative regulation of transcription by RNA polymeras... | catalytic complex; chromosome, centromeric region; heterochromatin; nucleoplasm; nucleus | chromatin binding DNA (cytosine-5-)-methyltransferase activity DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates DNA binding histone deacetylase binding metal ion binding methyltransferase activity transcription corepressor acti... | Mus musculus | 3D-structure Activator Alternative splicing Citrullination DNA-binding Isopeptide bond Metal-binding Methyltransferase Nucleus Phosphoprotein Reference proteome Repressor S-adenosyl-L-methionine Transferase Ubl conjugation Zinc Zinc-finger | MKGDSRHLNE | MKGDSRHLNEEEGASGYEECIIVNGNFSDQSSDTKDAPSPPVLEAICTEPVCTPETRGRRSSSRLSKREVSSLLNYTQDMTGDGDRDDEVDDGNGSDILMPKLTRETKDTRTRSESPAVRTRHSNGTSSLERQRASPRITRGRQGRHHVQEYPVEFPATRSRRRRASSSASTPWSSPASVDFMEEVTPKSVSTPSVDLSQDGDQEGMDTTQVDAESRDGDSTEYQDDKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMPGMRWVQWFGDGKFSEISADKLVALGLFSQHFNLATFNKLVSYRKAMYHTLEKARVRA... | autosome genomic imprinting C-5 methylation of cytosine cellular response to amino acid stimulus DNA methylation DNA methylation-dependent heterochromatin formation negative regulation of DNA-templated transcription negative regulation of gene expression, epigenetic negative regulation of transcription by RNA polymeras... |
animal organ morphogenesis DNA replication preinitiation complex assembly negative regulation of cell cycle negative regulation of DNA replication negative regulation of DNA-templated DNA replication negative regulation of DNA-templated transcription protein-containing complex assembly regulation of DNA-templated DNA r... | cytoplasm; cytosol; nucleoplasm; nucleus; transcription repressor complex | chromatin binding DNA-binding transcription factor binding histone deacetylase binding transcription corepressor activity | Mus musculus | 3D-structure Acetylation Cell cycle Coiled coil Cytoplasm DNA replication inhibitor Nucleus Phosphoprotein Reference proteome | MNLSMKQKQE | MNLSMKQKQEGAQENVKNSPVPRRTLKMIQPSADGSLVGRENELPKGLFKRKLWDDQLASQTSSCGPEANENKDVGDLTQEAFDLISKENPSSQYWKEVAEQRRKALYEALKENEKLHKEIEQKDSEIARLRKENKDLAEVAEHVQYMAEVIERLSNEPLDNFESPDSQEFDSEEEAVEYSELEDSGAGTCAEETVSSSTDARPCT | animal organ morphogenesis DNA replication preinitiation complex assembly negative regulation of cell cycle negative regulation of DNA replication negative regulation of DNA-templated DNA replication negative regulation of DNA-templated transcription protein-containing complex assembly regulation of DNA-templated DNA r... |
cell fate determination compartment pattern specification in utero embryonic development negative regulation of astrocyte differentiation negative regulation of neurogenesis negative regulation of Notch signaling pathway nervous system development Notch signaling pathway paraxial mesoderm development positive regulatio... | endosome membrane; plasma membrane | calcium ion binding Notch binding | Mus musculus | Alternative splicing Developmental protein Differentiation Disulfide bond EGF-like domain Membrane Notch signaling pathway Reference proteome Repeat Signal Transmembrane Transmembrane helix Ubl conjugation | MVSLQVSPLS | MVSLQVSPLSQTLILAFLLPQALPAGVFELQIHSFGPGPGLGTPRSPCNARGPCRLFFRVCLKPGVSQEATESLCALGAALSTSVPVYTEHPGESAAALPLPDGLVRVPFRDAWPGTFSLVIETWREQLGEHAGGPAWNLLARVVGRRRLAAGGPWARDVQRTGTWELHFSYRARCEPPAVGAACARLCRSRSAPSRCGPGLRPCTPFPDECEAPSVCRPGCSPEHGYCEEPDECRCLEGWTGPLCTVPVSTSSCLNSRVPGPASTGCLLPGPGPCDGNPCANGGSCSETSGSFECACPRGFYGLRCEVSGVTCADGPCF... | cell fate determination compartment pattern specification in utero embryonic development negative regulation of astrocyte differentiation negative regulation of neurogenesis negative regulation of Notch signaling pathway nervous system development Notch signaling pathway paraxial mesoderm development positive regulatio... |
anoikis B cell homeostasis canonical NF-kappaB signal transduction defense response to bacterium DNA damage response establishment of vesicle localization negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway positive regulation of canonical NF-kappaB signal transduction posi... | cytoplasm; cytosol; IkappaB kinase complex; mitotic spindle; nucleus; protein-containing complex; spindle pole; ubiquitin ligase complex | identical protein binding K63-linked polyubiquitin modification-dependent protein binding linear polyubiquitin binding metal ion binding peroxisome proliferator activated receptor binding polyubiquitin modification-dependent protein binding protein domain specific binding protein heterodimerization activity protein hom... | Mus musculus | 3D-structure Coiled coil Cytoplasm Direct protein sequencing Disulfide bond DNA damage Isopeptide bond Metal-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | MNKHPWKNQL | MNKHPWKNQLSEMVQPSGGPAEDQDMLGEESSLGKPAMLHLPSEQGTPETLQRCLEENQELRDAIRQSNQMLRERCEELLHFQVSQREEKEFLMCKFQEARKLVERLSLEKLDLRSQREQALKELEQLKKCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKDRQALEGRIRAVSEQVRQLESEREVLQQQHSVQVDQLRMQNQSVEAALRMERQAASEEKRKLAQLQAAYHQLFQDYDSHIKSSKGMQLEDLRQQLQQAEEALVAKQELIDKLKEEAEQHKIVMETVPVLKAQADIYKADFQAERHAREKLVEKKE... | anoikis B cell homeostasis canonical NF-kappaB signal transduction defense response to bacterium DNA damage response establishment of vesicle localization negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway positive regulation of canonical NF-kappaB signal transduction posi... |
circadian regulation of gene expression negative regulation of DNA-templated transcription negative regulation of fat cell differentiation negative regulation of glucocorticoid receptor signaling pathway negative regulation of TOR signaling oxidative stress-induced premature senescence positive regulation of canonical ... | chromatoid body; CLOCK-BMAL transcription complex; nucleus; PML body; transcription regulator complex | aryl hydrocarbon receptor binding DNA binding DNA-binding transcription factor activity E-box binding Hsp90 protein binding protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding transcription cis-regulatory region binding | Mesocricetus auratus | Acetylation Activator Biological rhythms Cytoplasm DNA-binding Isopeptide bond Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation Ubl conjugation | MADQRMDISS | MADQRMDISSTISDFMSPGPTDLLSSSLGTSGVDCNRKRKGSATDYQESMDTDKDDPHGRLEYAEHQGRIKNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKLTVLRMAVQHMKTLRGATNPYTEANYKPTFLSDDELKHLILRAADGFLFVVGCDRGKILFVSESVFKILNYSQNDLIGQSLFDYLHPKDIAKVKEQLSSSDTAPRERLIDAKTGLPVKTDITPGPSRLCSGARRSFFCRMKCNRPSVKVEDKDFASTCSKKKADRKSFCTIHSTGYLKSWPPTKMGLDEDNEPDNEGCNLSCLVAIGRL... | circadian regulation of gene expression negative regulation of DNA-templated transcription negative regulation of fat cell differentiation negative regulation of glucocorticoid receptor signaling pathway negative regulation of TOR signaling oxidative stress-induced premature senescence positive regulation of canonical ... |
adult locomotory behavior associative learning brain development grooming behavior lipid catabolic process lysosomal lumen acidification lysosome organization macromolecule catabolic process membrane raft organization negative regulation of apoptotic process negative regulation of cell growth negative regulation of neu... | axon; cytosol; dendrite; extracellular region; extracellular space; Golgi apparatus; intracellular membrane-bounded organelle; lysosome; membrane raft; neuronal cell body; nucleus; synaptic vesicle | lysophosphatidic acid binding palmitoyl-(protein) hydrolase activity palmitoyl-CoA hydrolase activity sulfatide binding | Mus musculus | Disulfide bond Glycoprotein Hydrolase Lysosome Reference proteome Secreted Signal | MASSCSRRLL | MASSCSRRLLAAALLPWCCAAWALGHLDPPSPPPLVIWHGMGDSCCNPMSMGVIKKMVEKEIPGIYVLSLEIGKNMMEDVENSFFLNVNVQVNMVCQILEKDPKLQQGYNAIGFSQGGQFLRAVAQRCPTPPMMTLISVGGQHQGVFGLPRCPGESSHICDFIRKSLNAGAYSKLVQERLVQAQYWHDPIKESVYRNYSIFLADINQERCVNESYKKNLMALKKFVMVKFFNDSIVDPVDSEWFGFYRSGQAKETIPLQESTLYTEDRLGLKKMDKAGKLVFLAKEGDHLQISKEWFTAHIIPFLK | adult locomotory behavior associative learning brain development grooming behavior lipid catabolic process lysosomal lumen acidification lysosome organization macromolecule catabolic process membrane raft organization negative regulation of apoptotic process negative regulation of cell growth negative regulation of neu... |
aminergic neurotransmitter loading into synaptic vesicle amino acid metabolic process catecholamine metabolic process dopamine biosynthetic process gene expression kidney development response to toxic substance serotonin biosynthetic process | axon; cytoplasm; neuronal cell body; synaptic vesicle | 5-hydroxy-L-tryptophan decarboxylase activity amino acid binding aromatic-L-amino-acid decarboxylase activity enzyme binding L-dopa decarboxylase activity protein domain specific binding pyridoxal phosphate binding | Mus musculus | Acetylation Catecholamine biosynthesis Decarboxylase Lyase Pyridoxal phosphate Reference proteome Repeat | MDSREFRRRG | MDSREFRRRGKEMVDYIADYLDGIEGRPVYPDVEPGYLRPLIPATAPQEPETYEDIIKDIEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMDWLGKMLELPEAFLAGRAGEGGGVIQGSASEATLVALLAARTKVIRQLQAASPEFTQAAIMEKLVAYTSDQAHSSVERAGLIGGIKLKAVPSDGNFSMRASALREALERDKAAGLIPFFVVATLGTTSCCSFDNLLEVGPICNQEGVWLHIDAAYAGSAFICPEFRYLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKRRT... | aminergic neurotransmitter loading into synaptic vesicle amino acid metabolic process catecholamine metabolic process dopamine biosynthetic process gene expression kidney development response to toxic substance serotonin biosynthetic process axon; cytoplasm; neuronal cell body; synaptic vesicle 5-hydroxy-L-tryptophan d... |
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway calcium-mediated signaling cell surface receptor signaling pathway cellular response to amyloid-beta complement receptor mediated signaling pathway defense response to bacterium G protein-coupled receptor signaling pathway immune response-regulat... | cytoplasm; plasma membrane | amyloid-beta binding complement receptor activity N-formyl peptide receptor activity RAGE receptor binding scavenger receptor binding signaling receptor activity | Mus musculus | Cell membrane Chemotaxis Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MESNYSIHLN | MESNYSIHLNGSEVVVYDSTISRVLWILSMVVVSITFFLGVLGNGLVIWVAGFRMPHTVTTIWYLNLALADFSFTATLPFLLVEMAMKEKWPFGWFLCKLVHIVVDVNLFGSVFLIALIALDRCICVLHPVWAQNHRTVSLARKVVVGPWIFALILTLPIFIFLTTVRIPGGDVYCTFNFGSWAQTDEEKLNTAITFVTTRGIIRFLIGFSMPMSIVAVCYGLIAVKINRRNLVNSSRPLRVLTAVVASFFICWFPFQLVALLGTVWFKETLLSGSYKILDMFVNPTSSLAYFNSCLNPMLYVFMGQDFRERFIHSLPYS... | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway calcium-mediated signaling cell surface receptor signaling pathway cellular response to amyloid-beta complement receptor mediated signaling pathway defense response to bacterium G protein-coupled receptor signaling pathway immune response-regulat... |
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway calcium-mediated signaling cell surface receptor signaling pathway cellular response to amyloid-beta chemotaxis complement receptor mediated signaling pathway defense response to bacterium G protein-coupled receptor signaling pathway immune respo... | cytoplasm; plasma membrane | amyloid-beta binding complement receptor activity N-formyl peptide receptor activity scavenger receptor binding signaling receptor activity | Mus musculus | Cell membrane Chemotaxis Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MEANSSIPLN | MEANSSIPLNGSEVVFYDSTTSRVLWILSVIVLSITFVLGVLGNGLVIWVAGFRMAHTVTTICYLNLALGDFSFMVTLPLHIISMVMKGKWLFGWFLCKFVLSIVHINLFVSVFLITLIAMDRCTCVLHPVWVQNHRTVSLARKVIVGAWILSLLLTLPHFLFLTTVRDARGEVHCTCNFESVVANPEEQLKVSITVSTATGIISFIIGFSLPMSFIAVCYGLMAAKICRKGFLNSSRPLRVLTAVAISFFMCWFPFQLIILLGNIWNKETPSSIHILLNPASTLASFNSCLNPILYVFLGQEFREKLIYSLSASLERAL... | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway calcium-mediated signaling cell surface receptor signaling pathway cellular response to amyloid-beta chemotaxis complement receptor mediated signaling pathway defense response to bacterium G protein-coupled receptor signaling pathway immune respo... |
bicellular tight junction assembly calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules cell adhesion cell junction maintenance cell-cell junction organization cellular response to butyrate cellular response to lead ion cellular response to transforming growth factor beta stimulus cellular... | apical plasma membrane; basolateral plasma membrane; bicellular tight junction; cell junction; cell-cell junction; lateral plasma membrane; membrane; plasma membrane; protein-containing complex; tight junction | identical protein binding structural molecule activity virus receptor activity | Mus musculus | Cell junction Cell membrane Disulfide bond Membrane Reference proteome Tight junction Transmembrane Transmembrane helix | MANAGLQLLG | MANAGLQLLGFILASLGWIGSIVSTALPQWKIYSYAGDNIVTAQAIYEGLWMSCVSQSTGQIQCKVFDSLLNLNSTLQATRALMVIGILLGLIAIFVSTIGMKCMRCLEDDEVQKMWMAVIGGIIFLISGLATLVATAWYGNRIVQEFYDPLTPINARYEFGQALFTGWAAASLCLLGGVLLSCSCPRKTTSYPTPRPYPKPTPSSGKDYV | bicellular tight junction assembly calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules cell adhesion cell junction maintenance cell-cell junction organization cellular response to butyrate cellular response to lead ion cellular response to transforming growth factor beta stimulus cellular... |
bicellular tight junction assembly calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules cell-cell adhesion | bicellular tight junction; cell-cell junction; membrane; plasma membrane | identical protein binding structural molecule activity | Mus musculus | 3D-structure Cell junction Cell membrane Disulfide bond Isopeptide bond Membrane Phosphoprotein Reference proteome Tight junction Transmembrane Transmembrane helix Ubl conjugation | MASLGVQLVG | MASLGVQLVGYILGLLGLLGTSIAMLLPNWRTSSYVGASIVTAVGFSKGLWMECATHSTGITQCDIYSTLLGLPADIQAAQAMMVTSSAMSSLACIISVVGMRCTVFCQDSRAKDRVAVVGGVFFILGGILGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISALFSLVAGVILCFSCSPQGNRTNYYDGYQAQPLATRSSPRSAQQPKAKSEFNSYSLTGYV | bicellular tight junction assembly calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules cell-cell adhesion bicellular tight junction; cell-cell junction; membrane; plasma membrane identical protein binding structural molecule activity Mus musculus 3D-structure Cell junction Cell membrane D... |
base-excision repair decidualization DNA ADP-ribosylation DNA damage response DNA repair DNA repair-dependent chromatin remodeling double-strand break repair extrinsic apoptotic signaling pathway hippocampal neuron apoptotic process positive regulation of cell growth involved in cardiac muscle cell development protein ... | nucleolus; nucleoplasm; nucleus; site of DNA damage | chromatin binding damaged DNA binding NAD DNA ADP-ribosyltransferase activity NAD+ ADP-ribosyltransferase activity NAD+- protein-aspartate ADP-ribosyltransferase activity NAD+-protein ADP-ribosyltransferase activity NAD+-protein-glutamate ADP-ribosyltransferase activity NAD+-protein-serine ADP-ribosyltransferase activi... | Mus musculus | 3D-structure Acetylation ADP-ribosylation Allosteric enzyme Chromosome DNA damage DNA repair DNA-binding Glycosyltransferase NAD Nucleotidyltransferase Nucleus Phosphoprotein Reference proteome Transferase | MAPRRQRSGS | MAPRRQRSGSGRRVLNEAKKVDNGNKATEDDSPPGKKMRTCQRKGPMAGGKDADRTKDNRDSVKTLLLKGKAPVDPECAAKLGKAHVYCEGDDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKTGQHSLVTCSGDLNKAKEIFQKKFLDKTKNNWEDRENFEKVPGKYDMLQMDYAASTQDESKTKEEETLKPESQLDLRVQELLKLICNVQTMEEMMIEMKYDTKRAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALVEACNEFYTRIPHDFGLSIPPVIRTEKELSDKVKLLEALGDIEIAL... | base-excision repair decidualization DNA ADP-ribosylation DNA damage response DNA repair DNA repair-dependent chromatin remodeling double-strand break repair extrinsic apoptotic signaling pathway hippocampal neuron apoptotic process positive regulation of cell growth involved in cardiac muscle cell development protein ... |
acyl-CoA metabolic process long-chain fatty acid metabolic process | endoplasmic reticulum; mitochondrial matrix; mitochondrial membrane; mitochondrion | arachidonate-CoA ligase activity ATP binding fatty-acyl-CoA synthase activity long-chain fatty acid transporter activity long-chain fatty acid-CoA ligase activity very long-chain fatty acid-CoA ligase activity | Mus musculus | Alternative splicing ATP-binding Fatty acid metabolism Ligase Lipid metabolism Lipid transport Membrane Mitochondrion Nucleotide-binding Reference proteome Transmembrane Transmembrane helix Transport | MAALLLLLPL | MAALLLLLPLLLLLPLLLKLDVWPQLRWLPADLAFTVRALRCKRALRARALAAAAADPESSESGCSLAWRLAYLAREQPTHTFLIHGAQRFSYAEAERESNRIARAFLRARGWTGGRRGSGRGSTEEGARVAPPAGDAAARGTTAPPLAPGATVALLLPAGPDFLWIWFGLAKAGLRTAFVPTALRRGPLLHCLRSCGASALVLATEFLESLEPDLPALRAMGLHLWATGPETNVAGISNLLSEAADQVDEPVPGYLSAPQNIMDTCLYIFTSGTTGLPKAARISHLKVLQCQGFYHLCGVHQEDVIYLALPLYHMSGSL... | acyl-CoA metabolic process long-chain fatty acid metabolic process endoplasmic reticulum; mitochondrial matrix; mitochondrial membrane; mitochondrion arachidonate-CoA ligase activity ATP binding fatty-acyl-CoA synthase activity long-chain fatty acid transporter activity long-chain fatty acid-CoA ligase activity very lo... |
G-quadruplex DNA unwinding miRNA transport mRNA export from nucleus mRNA processing mRNA splicing, via spliceosome mRNA transport negative regulation of mRNA splicing, via spliceosome negative regulation of transcription by RNA polymerase II positive regulation of telomere maintenance via telomere lengthening primary m... | Cajal body; catalytic step 2 spliceosome; chromatin; chromosome, telomeric region; cytoplasm; extracellular exosome; glutamatergic synapse; neuronal cell body; neuronal ribonucleoprotein granule; nuclear matrix; nucleoplasm; nucleus; perikaryon; postsynaptic cytosol; postsynaptic density; ribonucleoprotein complex; spl... | DNA polymerase binding G-rich strand telomeric DNA binding identical protein binding miRNA binding molecular condensate scaffold activity mRNA 3'-UTR binding mRNA CDS binding N6-methyladenosine-containing RNA reader activity pre-mRNA intronic binding regulatory region RNA binding RNA binding single-stranded telomeric D... | Mus musculus | Acetylation Alternative splicing Cytoplasm Direct protein sequencing Isopeptide bond Methylation mRNA processing mRNA splicing mRNA transport Nucleus Phosphoprotein Reference proteome Repeat Ribonucleoprotein RNA-binding Secreted Spliceosome Transport Ubl conjugation | MEKTLETVPL | MEKTLETVPLERKKREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAEVDAAMAARPHSIDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKEDTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSRQEMQEVQSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGGGNFGGSPGYGGGRGGYGGGGPGYGNQGGGYGGGYDNYGGGNYGSGSYNDFGNYNQQPSNYGPMKSGN... | G-quadruplex DNA unwinding miRNA transport mRNA export from nucleus mRNA processing mRNA splicing, via spliceosome mRNA transport negative regulation of mRNA splicing, via spliceosome negative regulation of transcription by RNA polymerase II positive regulation of telomere maintenance via telomere lengthening primary m... |
modulation by host of symbiont transcription negative regulation of cell migration negative regulation of stem cell population maintenance negative regulation of transcription by RNA polymerase II negative regulation of transforming growth factor beta receptor signaling pathway positive regulation of stem cell populati... | histone deacetylase complex; nucleoplasm; nucleus; Sin3-type complex | DNA binding metal ion binding transcription coregulator activity transcription corepressor activity | Mus musculus | 3D-structure DNA-binding Isopeptide bond Metal-binding Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | MNGFTPEEMS | MNGFTPEEMSRGGDAAAAVAAVVAAAAAAASAGNGNAAGGGAEVPGAGAVSASGPPGAAGPGPGQLCCLREDGERCGRAAGNASFSKRIQKSISQKKVKIELDKSARHLYICDYHKNLIQSVRNRRKRKGSDDDGGDSPVQDIDTPEVDLYQLQVNTLRRYKRHFKLPTRPGLNKAQLVEIVGCHFKSIPVNEKDTLTCFIYSVRNDKNKSDLKADSGVH | modulation by host of symbiont transcription negative regulation of cell migration negative regulation of stem cell population maintenance negative regulation of transcription by RNA polymerase II negative regulation of transforming growth factor beta receptor signaling pathway positive regulation of stem cell populati... |
amino acid transport glycine import across plasma membrane glycine transport L-proline import across plasma membrane proline import across plasma membrane proline transport sodium ion transmembrane transport | apical plasma membrane; brush border membrane; plasma membrane | amino acid transmembrane transporter activity L-proline transmembrane transporter activity neutral L-amino acid transmembrane transporter activity proline:sodium symporter activity solute:sodium symporter activity | Mus musculus | Cell membrane Glycoprotein Membrane Reference proteome Symport Transmembrane Transmembrane helix Transport | MESPSAHAVS | MESPSAHAVSLPEDEELQPWGGAGGPGQHPGRPRSTECAHPGVVEKVRPKWDNPLQFLLVCISYAVGLGNVWRFPYLCQMYGGGNFLVPYIIMLIVEGMPLLYLELAVGQRMRQGSIGAWRTISPYLSGVGIASLVVSFLASVYFNVINTWALWYLFHSFQDPLPWSVCPLNSNHTGYDEECEKASSTQYFWYRKTLNISPSIQENGGVQWEPALCLTLAWLMVYLCILRGTESTGKVVYFTTSLPYFVLIIYLVRGLTLHGATNGLAYMFTPKIEQLANPKAWINAATQIFFSLGLGCGGLIAFASYNEPSNDCQKHAL... | amino acid transport glycine import across plasma membrane glycine transport L-proline import across plasma membrane proline import across plasma membrane proline transport sodium ion transmembrane transport apical plasma membrane; brush border membrane; plasma membrane amino acid transmembrane transporter activity L-p... |
amino acid transmembrane transport neurotransmitter transport neutral amino acid transport renal amino acid absorption sodium ion transmembrane transport | apical plasma membrane; brush border membrane; plasma membrane | neutral L-amino acid transmembrane transporter activity neutral L-amino acid:sodium:chloride symporter activity | Mus musculus | Alternative splicing Amino-acid transport Cell membrane Glycoprotein Membrane Neurotransmitter transport Reference proteome Symport Transmembrane Transmembrane helix Transport | MAQASGMDPL | MAQASGMDPLVDIEDERPKWDNKLQYLLSCIGFAVGLGNIWRFPYLCQTHGGGAFLIPYFIALVFEGIPLFYIELAIGQRLRRGSIGVWKTISPYLGGVGLGCFSVSFLVSLYYNTVLLWVLWFFLNSFQHPLPWSTCPLDLNRTGFVQECQSSGTVSYFWYRQTLNITSDISNTGTIQWKLFLCLVACWSTVYLCVIRGIESTGKVIYFTALFPYLVLTIFLIRGLTLPGATEGLIYLFTPNMKTLQNPRVWLDAATQIFFSLSLAFGGHIAFASYNPPRNNCEKDAVIIALVNSMTSLYASIAIFSVMGFKASNDYGR... | amino acid transmembrane transport neurotransmitter transport neutral amino acid transport renal amino acid absorption sodium ion transmembrane transport apical plasma membrane; brush border membrane; plasma membrane neutral L-amino acid transmembrane transporter activity neutral L-amino acid:sodium:chloride symporter ... |
cellular response to hormone stimulus growth hormone receptor signaling pathway intracellular signal transduction lactation mammary gland alveolus development negative regulation of multicellular organism growth negative regulation of receptor signaling pathway via JAK-STAT phosphatidylinositol phosphate biosynthetic p... | phosphatidylinositol 3-kinase complex | 1-phosphatidylinositol-3-kinase regulator activity growth hormone receptor binding insulin-like growth factor receptor binding | Rattus norvegicus | Growth regulation Isopeptide bond Phosphoprotein Reference proteome SH2 domain Signal transduction inhibitor Ubl conjugation Ubl conjugation pathway | MTLRCLEPSG | MTLRCLEPSGNGADRTRSQWGTAGSPEDQSPEAARLAKALRELSQTGWYWGSMTVNEAKEKLKEAPEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGKFRLDSIICVKSKLKQFDSVVHLIDYYVQMCKDKRTGPEAPRNGTVHLYLTKPLYTSAPTLQHFCRLSINKCTGTIRGLPLPTRLKDYLEEYKFQV | cellular response to hormone stimulus growth hormone receptor signaling pathway intracellular signal transduction lactation mammary gland alveolus development negative regulation of multicellular organism growth negative regulation of receptor signaling pathway via JAK-STAT phosphatidylinositol phosphate biosynthetic p... |
antimicrobial humoral immune response mediated by antimicrobial peptide apoptotic process biological process involved in interaction with host defense response to Gram-positive bacterium detection of bacterium innate immune response killing of cells of another organism negative regulation of inflammatory response negat... | cytoplasm; extracellular space | cytokine activity Hsp70 protein binding molecular adaptor activity N-acetylmuramoyl-L-alanine amidase activity peptidoglycan binding peptidoglycan immune receptor activity receptor ligand activity zinc ion binding | Mus musculus | Antibiotic Antimicrobial Apoptosis Cytokine Cytoplasm Disulfide bond Immunity Innate immunity Reference proteome Secreted Signal | MLFACALLAL | MLFACALLALLGLATSCSFIVPRSEWRALPSECSSRLGHPVRYVVISHTAGSFCNSPDSCEQQARNVQHYHKNELGWCDVAYNFLIGEDGHVYEGRGWNIKGDHTGPIWNPMSIGITFMGNFMDRVPAKRALRAALNLLECGVSRGFLRSNYEVKGHRDVQSTLSPGDQLYQVIQSWEHYRE | antimicrobial humoral immune response mediated by antimicrobial peptide apoptotic process biological process involved in interaction with host defense response to Gram-positive bacterium detection of bacterium innate immune response killing of cells of another organism negative regulation of inflammatory response negat... |
chaperone-mediated protein complex assembly kidney development negative regulation of apoptotic process negative regulation of gene expression negative regulation of protein phosphorylation neuron apoptotic process positive regulation of angiogenesis protein folding protein insertion into mitochondrial outer membrane r... | cytosol; extracellular exosome; lipid droplet; mitochondrion; nucleus | adenyl-nucleotide exchange factor activity ATP binding ATP-dependent protein folding chaperone protein-containing complex binding RNA polymerase II-specific DNA-binding transcription factor binding | Rattus norvegicus | Acetylation ATP-binding Cytoplasm Direct protein sequencing Methylation Nucleotide-binding Phosphoprotein Reference proteome Stress response | MSVVGIDLGF | MSVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACVSFGPKNRSVGAAAKSQVISNAKNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAMLLSKLKETAESVLKKPVVDCVVSVPSFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAYGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLVNHFCEEFGKKYKLDIKSKVRALLRLSQECEKLKKLMSANASDLPLSIECFMNDIDVSGTMNRGKFLEMCDDLLARVEPP... | chaperone-mediated protein complex assembly kidney development negative regulation of apoptotic process negative regulation of gene expression negative regulation of protein phosphorylation neuron apoptotic process positive regulation of angiogenesis protein folding protein insertion into mitochondrial outer membrane r... |
eye blink reflex membrane depolarization membrane hyperpolarization nervous system process neuromuscular junction development neurotransmitter receptor internalization neurotransmitter receptor localization to postsynaptic specialization membrane neurotransmitter receptor transport, postsynaptic endosome to lysosome po... | AMPA glutamate receptor complex; cell surface; cerebellar mossy fiber; glutamatergic synapse; hippocampal mossy fiber to CA3 synapse; postsynaptic density membrane; Schaffer collateral - CA1 synapse; somatodendritic compartment; voltage-gated calcium channel complex | channel regulator activity ionotropic glutamate receptor binding voltage-gated calcium channel activity | Mus musculus | 3D-structure Calcium Calcium channel Calcium transport Glycoprotein Ion channel Ion transport Membrane Phosphoprotein Reference proteome Synapse Synaptosome Transmembrane Transmembrane helix Transport Voltage-gated channel | MGLFDRGVQM | MGLFDRGVQMLLTTVGAFAAFSLMTIAVGTDYWLYSRGVCKTKSVSENETSKKNEEVMTHSGLWRTCCLEGNFKGLCKQIDHFPEDADYEADTAEYFLRAVRASSIFPILSVILLFMGGLCIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVYISANAGDPSKSDSKKNSYSYGWSFYFGALSFIIAEMVGVLAVHMFIDRHKQLRATARATDYLQASAITRIPSYRYRYQRRSRSSSRSTEPSHSRDASPVGVKGFNTLPSTEISMYTLSRDPLKAATTPTATYNSDRDNSFLQVHNCIQKDSKDSLHANTANRRT... | eye blink reflex membrane depolarization membrane hyperpolarization nervous system process neuromuscular junction development neurotransmitter receptor internalization neurotransmitter receptor localization to postsynaptic specialization membrane neurotransmitter receptor transport, postsynaptic endosome to lysosome po... |
camera-type eye development cell population proliferation central nervous system neuron development cerebellum morphogenesis collagen fibril organization dopaminergic neuron differentiation dorsal/ventral pattern formation embryonic limb morphogenesis limb morphogenesis locomotory behavior memory midbrain development n... | nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific metal ion binding RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA... | Mus musculus | Activator Developmental protein DNA-binding Homeobox LIM domain Metal-binding Nucleus Reference proteome Repeat Transcription Transcription regulation Zinc | MDIATGPESL | MDIATGPESLERCFPRGQTDCAKMLDGIKMEEHALRPGPATLGVLLGSDCPHPAVCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALTTSCYFRDRKLYCKQDYQQLFAAKCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCKGDYEKEKDLLSSVSPDESDSVKSEDEDGDMKPAKGQGSQSKGSGDDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRHQQQQEQQNSQRLGQEVLSSRMEGMMASYTPLAPPQQQIV... | camera-type eye development cell population proliferation central nervous system neuron development cerebellum morphogenesis collagen fibril organization dopaminergic neuron differentiation dorsal/ventral pattern formation embryonic limb morphogenesis limb morphogenesis locomotory behavior memory midbrain development n... |
cytoskeleton organization histidine catabolic process to glutamate and formamide histidine catabolic process to glutamate and formate | centriole; cytosol; endoplasmic reticulum; endoplasmic reticulum-Golgi intermediate compartment; Golgi apparatus; Golgi membrane; plasma membrane; smooth endoplasmic reticulum membrane | folic acid binding formimidoyltetrahydrofolate cyclodeaminase activity glutamate formimidoyltransferase activity intermediate filament binding microtubule binding | Rattus norvegicus | 3D-structure Cytoplasm Cytoskeleton Direct protein sequencing Folate-binding Golgi apparatus Histidine metabolism Lyase Multifunctional enzyme Phosphoprotein Reference proteome Transferase | MSQLVECVPN | MSQLVECVPNFSEGNNQEVIDAISQAISQTPGCVLLDVDAGPSTNRTVYTFVGQPECVVEGALSAARTASQLIDMRKHKGEHPRMGALDVCPFIPVRGVSMDECVLCAKAFGQRLAEELNVPVYLYGEAAQMPSRQTLPAIRAGEYEALPEKLKQAEWVPDFGPSSFVPSWGATVTGARKFLIAFNINLLSTKEQAHRIALNLREQGRGKDQPGRLKKVQGIGWYLEEKNLAQVSTNLLDFEVTALHTVYEEARREAQELNLPVVGSQLVGLVPLKALLDAAAFYCDKEKLFVLEEEHRIRLVVNRLGLDSLAPFDPKER... | cytoskeleton organization histidine catabolic process to glutamate and formamide histidine catabolic process to glutamate and formate centriole; cytosol; endoplasmic reticulum; endoplasmic reticulum-Golgi intermediate compartment; Golgi apparatus; Golgi membrane; plasma membrane; smooth endoplasmic reticulum membrane f... |
anterior/posterior pattern specification aorta morphogenesis axial mesoderm development cardiac right ventricle morphogenesis cellular response to cytokine stimulus determination of left/right symmetry embryonic heart tube anterior/posterior pattern specification heart looping hepatocyte differentiation negative regula... | activin responsive factor complex; chromatin; nucleoplasm; nucleus; transcription regulator complex | bHLH transcription factor binding co-SMAD binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor binding nuclear androgen receptor binding protein domain specific binding R-SMAD binding sequence-specific DNA... | Mus musculus | Activator Alternative splicing DNA-binding Nucleus Reference proteome Transcription Transcription regulation | MASGWDLAST | MASGWDLASTYTPTTPSPQLALAPAQGYLPCMGPRDNSQLRPPEAESLSKTPKRRKKRYLRHDKPPYTYLAMIALVIQAAPFRRLKLAQIIRQVQAVFPFFRDDYEGWKDSIRHNLSSNRCFHKVPKDPAKPQAKGNFWAVDVSLIPAEALRLQNTALCRRWQNRGTHRAFAKDLSPYVLHGQPYQPPSPPPPPREGFSIKSLLGDPGKESTWPQHPGLPGQSTAAQAGTLSKGEEGMGTGPSSSSETPLWPLCSLPGPTIIEGESSQGEVIRPSPVTPDQGSWPLHLLEDSADSRGVPRRGSRASLWGQLPTSYLPIYT... | anterior/posterior pattern specification aorta morphogenesis axial mesoderm development cardiac right ventricle morphogenesis cellular response to cytokine stimulus determination of left/right symmetry embryonic heart tube anterior/posterior pattern specification heart looping hepatocyte differentiation negative regula... |
ATP generation from poly-ADP-D-ribose carbohydrate metabolic process detection of bacterium DNA damage response nucleotide-sugar metabolic process positive regulation of DNA repair regulation of DNA repair | chromatin; cytoplasm; cytosol; nuclear body; nucleoplasm; nucleus | chromatin binding poly(ADP-ribose) glycohydrolase activity | Mus musculus | 3D-structure Acetylation Alternative splicing DNA damage Hydrolase Nucleus Phosphoprotein Reference proteome | MSAGPGWEPC | MSAGPGWEPCTKRPRWGAAGTSAPTASDSRSFPGRQRRVLDPKDAPVQFRVPPSSPACVSGRAGPHRGNATSFVFKQKTITTWMDTKGPKTAESESKENNNTRIDSMMSSVQKDNFYPHKVEKLENVPQLNLDKSPTEKSSQYLNQQQTASVCKWQNEGKHAEQLLASEPPAGTPLPKQLSNANIGQSPHTDDHSDTDHEEDRDNQQFLTPIKLANTKPTVGDGQARSNCKCSGSRQSVKDCTGCQQEEVDVLPESPLSDVGAEDIGTGPKNDNKLTGQESSLGDSPPFEKESEPESPMDVDNSKNSCQDSEADEETSPV... | ATP generation from poly-ADP-D-ribose carbohydrate metabolic process detection of bacterium DNA damage response nucleotide-sugar metabolic process positive regulation of DNA repair regulation of DNA repair chromatin; cytoplasm; cytosol; nuclear body; nucleoplasm; nucleus chromatin binding poly(ADP-ribose) glycohydrolas... |
cell cycle circadian behavior circadian regulation of gene expression entrainment of circadian clock by photoperiod locomotor rhythm muscle organ development negative regulation of calcium ion transport negative regulation of skeletal muscle tissue development negative regulation of transcription by RNA polymerase II p... | centrosome; cytoplasm; membrane; nucleus; perinuclear region of cytoplasm | cyclin binding cysteine-type deubiquitinase activity identical protein binding metal ion binding ubiquitin protein ligase binding | Mus musculus | Alternative splicing Biological rhythms Cell cycle Cytoplasm Hydrolase Membrane Metal-binding Myogenesis Nucleus Protease Reference proteome Thiol protease Ubl conjugation pathway Zinc | MSQLSSTLKR | MSQLSSTLKRYTESSRYTDAPYAKPGYGTYTPSSYGANLAASFLEKEKLGFKPVSPTSFLPRPRTYGPSSILDCDRGRPLLRSDIIGSSKRSESQTRGNERPSGSGLNGGSGFSYGVSSNSLSYLPMNARDQGVTLSQKKSNSQSDLARDFSSLRTSDGYRTSDGYRTSEGFRIDPGNLGRSPMLARTRKELCALQGLYQAASRSEYLTDYLENYGRKGSAPQVLTQAPPPSRVPEVLSPTYRPSGRYTLWEKSKGQASGPSRSSSPGRDTMNSKSAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLGH... | cell cycle circadian behavior circadian regulation of gene expression entrainment of circadian clock by photoperiod locomotor rhythm muscle organ development negative regulation of calcium ion transport negative regulation of skeletal muscle tissue development negative regulation of transcription by RNA polymerase II p... |
adenosine transport inosine transport neurotransmitter transport nucleoside transmembrane transport protein localization to cell surface purine nucleobase transmembrane transport purine nucleoside transmembrane transport pyrimidine-containing compound transmembrane transport retina homeostasis uridine transport | apicolateral plasma membrane; brush border membrane; coated vesicle; plasma membrane; vesicle membrane | neurotransmitter transmembrane transporter activity nucleoside transmembrane transporter activity nucleoside:sodium symporter activity purine nucleobase transmembrane transporter activity purine nucleoside transmembrane transporter activity pyrimidine- and adenosine-specific:sodium symporter activity uridine transmembr... | Mus musculus | Cell membrane Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport | MEKSKGRKSV | MEKSKGRKSVSQATVENCMENPGLELMEGGNLEQRYTQEEVTQGHSLEDGLGHSSLWSRRIFQPFTKARSFFERHAGLFRKILLGLLCLAYAAYFLAACILNFQRALALFVITCLVIFILACHFLKKFFPKEQLRCLKPLENTHLNLWAKRVFVGLSVVGLILWLALDTAQRPEQLISFAGICMFILILFACSKHHSAVCWRTVFWGLGLQFIFGILVIRTEPGFNAFQWLGDQIQIFLAYTVEGSSFVFGDTLVQNVFAFQSLPIIIFFGCVMSILYYLGLVQWVIQKVAWFLQITMGTTAAETLAVAGNIFVGMTEAP... | adenosine transport inosine transport neurotransmitter transport nucleoside transmembrane transport protein localization to cell surface purine nucleobase transmembrane transport purine nucleoside transmembrane transport pyrimidine-containing compound transmembrane transport retina homeostasis uridine transport apicola... |
endoplasmic reticulum to Golgi vesicle-mediated transport protein transport retrograde transport, endosome to Golgi vesicle fusion | cis-Golgi network; cytosol; Golgi apparatus; Golgi medial cisterna; Golgi membrane; membrane; SNARE complex | SNAP receptor activity | Mus musculus | Acetylation Coiled coil Direct protein sequencing ER-Golgi transport Golgi apparatus Membrane Phosphoprotein Protein transport Reference proteome Transmembrane Transmembrane helix Transport | MAAGTSNYWE | MAAGTSNYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSGSRDGGRDRYSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAEYTHSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFTAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNSDRLIEETISIAMATKENMTSQRGMLKSIHSKMNTLANRFPAVNSLIQRINLRKRRDSLILGGVIGICTILLLLYAFH | endoplasmic reticulum to Golgi vesicle-mediated transport protein transport retrograde transport, endosome to Golgi vesicle fusion cis-Golgi network; cytosol; Golgi apparatus; Golgi medial cisterna; Golgi membrane; membrane; SNARE complex SNAP receptor activity Mus musculus Acetylation Coiled coil Direct protein sequen... |
axon extension involved in axon guidance axon guidance branchiomotor neuron axon guidance facial nerve structural organization negative chemotaxis negative regulation of axon extension involved in axon guidance nerve development neural crest cell migration neural crest cell migration involved in autonomic nervous syste... | extracellular space; glutamatergic synapse | chemorepellent activity semaphorin receptor binding | Mus musculus | Alternative splicing Disulfide bond Glycoprotein Immunoglobulin domain Reference proteome Secreted Signal | MLVTAFILWA | MLVTAFILWASLLTGAWPATPIQDQLPATPRVRLSFKELKATGTAHFFNFLLNTTDYRILLKDEDHDRMYVGSKDYVLSLDLHDINREPLIIHWAASPQRIEECILSGKDGNGECGNFVRLIQPWNRTHLYVCGTGAYNPMCTYVNRGRRAQALPWTQMQVVRGRGSRATDGADRPTPTAPRQDYIFYLEPEKLESGKGKCPYDPKLDTASALINEELYAGVYIDFMGTDAAIFRTLGKQTAMRTDQYNSRWLNDPSFIHAELIPDSAERNDDKLYFFFRERSAEAPQNPAVYARIGRICLNDDGGHCCLVNKWSTFLKA... | axon extension involved in axon guidance axon guidance branchiomotor neuron axon guidance facial nerve structural organization negative chemotaxis negative regulation of axon extension involved in axon guidance nerve development neural crest cell migration neural crest cell migration involved in autonomic nervous syste... |
phospholipase C-activating G protein-coupled receptor signaling pathway platelet activation platelet aggregation positive regulation of release of sequestered calcium ion into cytosol positive regulation of Rho protein signal transduction | plasma membrane | G protein-coupled receptor activity protease binding thrombin-activated receptor activity | Mus musculus | 3D-structure Blood coagulation Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Hemostasis Membrane Receptor Reference proteome Signal Transducer Transmembrane Transmembrane helix | MCWPLLYPLV | MCWPLLYPLVLGLSISLAEGIQTPSIYDDVESTRGSHEGPLGPTVELKEPKSSDKPNPRGYPGKFCANDSDTLELPASSQALLLGWVPTRLVPALYGLVVAVGLPANGLALWVLATRVPRLPSTILLMNLAVADLLLALVLPPRLAYHLRGQRWPFGEAACRVATAALYGHMYGSVLLLAAVSLDRYLALVHPLRARALRGQRLTTGLCLVAWLSAATLALPLTLHRQTFRLAGSDRMLCHDALPLTEQTSHWRPAFICLAVLGCFVPLLAMGLCYGATLRALAANGQRYSHALRLTALVLFSAVASFTPSNVLLVLHYS... | phospholipase C-activating G protein-coupled receptor signaling pathway platelet activation platelet aggregation positive regulation of release of sequestered calcium ion into cytosol positive regulation of Rho protein signal transduction plasma membrane G protein-coupled receptor activity protease binding thrombin-act... |
cellular response to amino acid stimulus positive regulation of MAPK cascade positive regulation of TOR signaling positive regulation of TORC1 signaling protein localization protein localization to cell junction TORC1 signaling | FNIP-folliculin RagC/D GAP; late endosome; late endosome membrane; lysosomal membrane; Ragulator complex | guanyl-nucleotide exchange factor activity kinase activator activity molecular adaptor activity | Mus musculus | 3D-structure Direct protein sequencing Endosome Membrane Reference proteome | MADDLKRFLY | MADDLKRFLYKKLPSVEGLHAIVVSDRDGVPVIKVANDSAPEHALRPGFLSTFALATDQGSKLGLSKNKSIICYYNTYQVVQFNRLPLVVSFIASSSANTGLIVSLEKELAPLFEELIKVVEVS | cellular response to amino acid stimulus positive regulation of MAPK cascade positive regulation of TOR signaling positive regulation of TORC1 signaling protein localization protein localization to cell junction TORC1 signaling FNIP-folliculin RagC/D GAP; late endosome; late endosome membrane; lysosomal membrane; Ragul... |
central nervous system neuron development DNA damage response DNA repair execution phase of apoptosis microtubule cytoskeleton organization mitotic G2 DNA damage checkpoint signaling negative regulation of microtubule depolymerization neuron cellular homeostasis phosphorylation positive regulation of JNK cascade positi... | cytoplasm; microtubule cytoskeleton; perinuclear region of cytoplasm | alpha-tubulin binding ATP binding beta-tubulin binding kinase activity myosin V binding protein kinase activator activity protein kinase activity protein kinase binding protein serine kinase activity protein serine/threonine kinase activator activity protein serine/threonine kinase activity | Rattus norvegicus | Apoptosis ATP-binding Coiled coil Cytoplasm DNA damage DNA repair Kinase Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MPSTNRAGSL | MPSTNRAGSLKDPEIAELFFKEDPEKLFTDLREIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPNSIEYKGCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPTLQSNEWSDYFRNFVDSCLQKIPQDRPTSEELLKHMFVLRERPETVLIDLIQRTKDAVRELDNLQYRKMKKLLFQEA... | central nervous system neuron development DNA damage response DNA repair execution phase of apoptosis microtubule cytoskeleton organization mitotic G2 DNA damage checkpoint signaling negative regulation of microtubule depolymerization neuron cellular homeostasis phosphorylation positive regulation of JNK cascade positi... |
cell cycle chromatin remodeling negative regulation of DNA-templated transcription negative regulation of G1/S transition of mitotic cell cycle positive regulation of cell differentiation positive regulation of double-strand break repair positive regulation of myoblast differentiation positive regulation of T cell diff... | chromatin; cytosol; kinetochore; nuclear matrix; nucleoplasm; nucleus; RSC-type complex | histone binding lysine-acetylated histone binding p53 binding transcription cis-regulatory region binding transcription coactivator activity transcription corepressor activity | Mus musculus | Acetylation Bromodomain Cell cycle Chromosome Coiled coil Isopeptide bond Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Tumor suppressor Ubl conjugation Wnt signaling pathway | MGKKHKKHKS | MGKKHKKHKSDRHFYEEYVEKPLKLVLKVGGSEVTELSTGSSGHDSSLFEDRSDHDKHKDRKRKKRKKGEKQAPGEEKGRKRRRVKEDKKKRDRDRAENEVDRDLQCHVPIRLDLPPEKPLTSSLAKQEEVEQTPLQEALNQLMRQLQRKDPSAFFSFPVTDFIAPGYSMIIKHPMDFSTMKEKIKNNDYQSIEELKDNFKLMCTNAMIYNKPETIYYKAAKKLLHSGMKILSQERIQSLKQSIDFMSDLQKTRKQKERTDACQSGEDSGCWQREREDSGDAETQAFRSPAKDNKRKDKDVLEDKWRSSNSEREHEQIER... | cell cycle chromatin remodeling negative regulation of DNA-templated transcription negative regulation of G1/S transition of mitotic cell cycle positive regulation of cell differentiation positive regulation of double-strand break repair positive regulation of myoblast differentiation positive regulation of T cell diff... |
negative regulation of cell growth | plasma membrane; T-tubule | calcium channel regulator activity calmodulin binding GTP binding GTPase activity | Mus musculus | Calmodulin-binding Cell membrane GTP-binding Membrane Methylation Nucleotide-binding Phosphoprotein Reference proteome | MTLNGGSGAS | MTLNGGSGASGSRGAGGRERDRRRGSTPWGPAPPLHRRSMPVDERDLQAALAPGSLATTAAGTRTQGQRLDWPEGSSDSLSSGGSGSEEGVYKVLLLGAPGVGKSALARIFGGIEDGPEAEAAGHTYDRSITVDGEEASLLVYDIWEEDGGCWLPGHCMAMGDAYVIVYSITDKGSFEKASELRVQLRRARQTDDVPIILVGNKSDLVRSREVSVDEGRACAVVFDCKFIETSAALHHNVQALFEGVVRQIRLRRDSKEDNARRQAGTRRRESLGKKAKRFLGRIVARNSRKMAFRAKSKSCHDLSVL | negative regulation of cell growth plasma membrane; T-tubule calcium channel regulator activity calmodulin binding GTP binding GTPase activity Mus musculus Calmodulin-binding Cell membrane GTP-binding Membrane Methylation Nucleotide-binding Phosphoprotein Reference proteome MTLNGGSGAS MTLNGGSGASGSRGAGGRERDRRRGSTPWGPAPP... |
autophagy endocytosis lysosomal lumen acidification lysosome organization regulation of DNA-templated transcription | endosome; extracellular space; lysosome; transcription regulator complex | insulin-like growth factor receptor binding | Mus musculus | Glycoprotein Growth regulation Reference proteome Secreted Signal | MAARAPELAR | MAARAPELARSLLAALLAPALVALLVSPASGRGGRDHGDWDVDRRLPPLPPREDGPRVARFVTHVSDWGSLATISTIKEVRGWPFADIISISDGPPGEGTGEPYMYLSPLQQAVSDLQENPEATLTMSLAQTVYCRNHGFDPQSPLCVHIMMSGTVTKVNKTEEDYARDSLFVRHPEMKHWPSSHNWFFAKLKISRIWVLDYFGGPKVVTPEEYFNVTLQ | autophagy endocytosis lysosomal lumen acidification lysosome organization regulation of DNA-templated transcription endosome; extracellular space; lysosome; transcription regulator complex insulin-like growth factor receptor binding Mus musculus Glycoprotein Growth regulation Reference proteome Secreted Signal MAARAPEL... |
cell fate determination compartment pattern specification negative regulation of astrocyte differentiation negative regulation of neurogenesis negative regulation of Notch signaling pathway Notch signaling pathway paraxial mesoderm development positive regulation of neurogenesis skeletal system development somitogenesi... | plasma membrane | calcium ion binding Notch binding | Rattus norvegicus | Developmental protein Differentiation Disulfide bond EGF-like domain Membrane Notch signaling pathway Reference proteome Repeat Signal Transmembrane Transmembrane helix Ubl conjugation | MVSLQVSSLP | MVSLQVSSLPQTLILAFLLPQALPAGVFELQIHSFGPGPGPGTPRSPCNARGPCRLFFRVCLKPGVSQEAAESLCALGAALSTSGPVYTEQPGVPAAALSLPDGLVRVPFLDAWPGTFSLIIETWREQLGERAAGPAWNLLARVAGRRRLAAGAPWARDVQRTGAWELHFSYRARCEPPAVGAACARLCRSRSAPSRCGPGLRPCTPFPDECEAPRESLTVCRAGCSPEHGYCEEPDECHCLEGWTGPLCTVPVSTSSCLNSRVSGPAGTGCLLPGPGPCDGNPCANGGSCSETPGSFECACPRGFYGPRCEVSGVTCAD... | cell fate determination compartment pattern specification negative regulation of astrocyte differentiation negative regulation of neurogenesis negative regulation of Notch signaling pathway Notch signaling pathway paraxial mesoderm development positive regulation of neurogenesis skeletal system development somitogenesi... |
diacylglycerol metabolic process glycerolipid metabolic process intracellular signal transduction lipid phosphorylation phosphatidic acid biosynthetic process protein kinase C-activating G protein-coupled receptor signaling pathway | cytosol; plasma membrane | alkylglycerol kinase activity ATP binding ATP-dependent diacylglycerol kinase activity calcium ion binding kinase activity lipid binding phospholipid binding | Mus musculus | Acetylation ATP-binding Calcium Cytoplasm Kinase Lipid metabolism Metal-binding Nucleotide-binding Reference proteome Repeat Transferase Zinc Zinc-finger | MAKEKGLISP | MAKEKGLISPEDFAQLQKYIEYSTKRVSDVLKVFDDGEMNRFCQGDAIGYLGFEQFMKMYLEMEEVPHHLCWALFWSFHTSQVAAEKTKSKANVICLSDVYCYFTLLEGGRPEDKLEFTFKLYDMDRNGILDSTEVEKIILQMMRVAEYLDWDVSELRPILQEMMREMDQDGSGSVSLDEWVRAGATTVPLLVLLGMDVTMKDDGNHIWRPKRFTRLVYCNLCEQSISLGKQGLSCNFCKYIVHDHCAMKAQPCEVSTYAKSRKDIGVQSHLWVRGGCHSGRCDRCQKKIRTYHSLTGLHCVWCHLEIHDDCLQAVGPEC... | diacylglycerol metabolic process glycerolipid metabolic process intracellular signal transduction lipid phosphorylation phosphatidic acid biosynthetic process protein kinase C-activating G protein-coupled receptor signaling pathway cytosol; plasma membrane alkylglycerol kinase activity ATP binding ATP-dependent diacylg... |
collagen catabolic process extracellular matrix organization proteolysis reproduction | endoplasmic reticulum membrane; extracellular matrix; extracellular space | metalloendopeptidase activity zinc ion binding | Mus musculus | Alternative splicing Cleavage on pair of basic residues Disulfide bond Endoplasmic reticulum Glycoprotein Hydrolase Immunoglobulin domain Membrane Metal-binding Protease Reference proteome Signal-anchor Transmembrane Transmembrane helix Zinc Zymogen | MGCRACLRPE | MGCRACLRPEASGAVQGRWLGAALSGLCLLSALALLEWLGAPTETAWRAAQGNVDAPNVGSSTAQVPRLLTMSVTRRRRYTLTPARLRWDHFNLTYRVLSFPRNLLSPEETRRGLAAAFRMWSDVSPFSFREVAPERPSDLKIGFYPVNHTDCLVSAVHHCFDGPTGELAHAFFPPHGGIHFDDSEYWVLGPTRYSWKKGVWLTNLVHVAAHEIGHALGLMHSQQDQALMHLNATLRGWKALSQDELWGLHRLYGCLDRIFVCASWARKGFCDVRQRLMKRLCPRSCDFCYEFPFPTVATTTSPTRTKTRLVREGRNMTF... | collagen catabolic process extracellular matrix organization proteolysis reproduction endoplasmic reticulum membrane; extracellular matrix; extracellular space metalloendopeptidase activity zinc ion binding Mus musculus Alternative splicing Cleavage on pair of basic residues Disulfide bond Endoplasmic reticulum Glycopr... |
cell adhesion homophilic cell adhesion via plasma membrane adhesion molecules | endoplasmic reticulum; membrane; plasma membrane; synapse | calcium ion binding identical protein binding | Mus musculus | 3D-structure Alternative splicing Calcium Cell adhesion Cell membrane Disulfide bond Glycoprotein Membrane Metal-binding Reference proteome Repeat Signal Transmembrane Transmembrane helix | MEFSWGSGQE | MEFSWGSGQESQRLLLSFLLLAIWEAGNSQIHYSIPEEAKHGTFVGRIAQDLGLELTELVPRLFRVASKDRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVRDINDNPPRFPTTQKNLFIAESRPLDTWFPLEGASDADIGINAVLTYRLSPNDYFSLEKPSNDERVKGLGLVLRKSLDREETPEIILVLTVTDGGKPELTGSVQLLITVLDANDNAPVFDRSLYTVKLPENVPNGTLVVKVNASDLDEGVNGDIMYSFSTDISPNVKYKFHIDPVSGEIIVKGYIDFEECKSYEILI... | cell adhesion homophilic cell adhesion via plasma membrane adhesion molecules endoplasmic reticulum; membrane; plasma membrane; synapse calcium ion binding identical protein binding Mus musculus 3D-structure Alternative splicing Calcium Cell adhesion Cell membrane Disulfide bond Glycoprotein Membrane Metal-binding Refe... |
cell differentiation cornified envelope assembly establishment of skin barrier glucosylceramide biosynthetic process intestinal lipid absorption keratinocyte differentiation leptin-mediated signaling pathway neuron development protein lipidation regulation of signal transduction | Golgi membrane; membrane | ceramide glucosyltransferase activity dihydroceramide glucosyltransferase activity | Mus musculus | Acetylation Glycosyltransferase Golgi apparatus Lipid biosynthesis Lipid metabolism Membrane Reference proteome Sphingolipid metabolism Transferase Transmembrane Transmembrane helix | MALLDLAQEG | MALLDLAQEGMALFGFVLFVVLWLMHFMSIIYTRLHLNKKATDKQPYSKLPGVSLLKPLKGVDPNLINNLETFFELDYPKYEVLLCVQDHDDPAIDVCKKLLGKYPNVDARLFIGGKKVGINPKINNLMPAYEVAKYDLIWICDSGIRVIPDTLTDMVNQMTEKVGLVHGLPYVADRQGFAATLEQVYFGTSHPRSYISANVTGFKCVTGMSCLMRKDVLDQAGGLIAFAQYIAEDYFMAKAIADRGWRFSMSTQVAMQNSGSYSISQFQSRMIRWTKLRINMLPATIICEPISECFVASLIIGWAAHHVFRWDIMVFFM... | cell differentiation cornified envelope assembly establishment of skin barrier glucosylceramide biosynthetic process intestinal lipid absorption keratinocyte differentiation leptin-mediated signaling pathway neuron development protein lipidation regulation of signal transduction Golgi membrane; membrane ceramide glucos... |
membrane protein proteolysis protein quality control for misfolded or incompletely synthesized proteins proteolysis proteolysis involved in protein catabolic process | endopeptidase Clp complex; mitochondrial matrix; mitochondrion | ATP-dependent peptidase activity ATPase binding endopeptidase activity identical protein binding serine-type endopeptidase activity | Mus musculus | Acetylation Hydrolase Mitochondrion Protease Reference proteome Serine protease Transit peptide | MWPRVLLGEA | MWPRVLLGEARVAVDGCRALLSRLAVHFSPPWTAVSCSPLRRSLHGTATRAFPLIPIVVEQTGRGERAYDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSESNKKPIHMYINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLAAGSPGMRHSLPNSRIMIHQPSGGARGQATDIAIQAEEIMKLKKQLYNIYAKHTKQSLQVIESAMERDRYMSPMEAQEFGILDKVLVHPPQDGEDEPELVQKETATAPTDPPAPTST | membrane protein proteolysis protein quality control for misfolded or incompletely synthesized proteins proteolysis proteolysis involved in protein catabolic process endopeptidase Clp complex; mitochondrial matrix; mitochondrion ATP-dependent peptidase activity ATPase binding endopeptidase activity identical protein bi... |
cellular response to transforming growth factor beta stimulus positive regulation of transcription by RNA polymerase II protein autophosphorylation protein phosphorylation | cytoplasm; cytosol; Golgi apparatus; Golgi-associated vesicle; nucleoplasm; perinuclear region of cytoplasm; plasma membrane | ATP binding non-membrane spanning protein tyrosine kinase activity protein kinase activity protein serine kinase activity protein serine/threonine kinase activity RNA polymerase II cis-regulatory region sequence-specific DNA binding | Mus musculus | ATP-binding Cytoplasm Kinase Lipoprotein Membrane Myristate Nucleotide-binding Palmitate Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MGHALCVCSR | MGHALCVCSRGTVIIDNKRYLFVQKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDQEEAQREAEMHRLFQHPNILRLMAYSLKERGAKHEAWLLLPFFKKGTLWNEIERLKDQGSFLTEDQILPLLLGISRGLEAIHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIQVEGSRQALALQDWAAQRCTISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQNELSIPQSPRHSSALRQLLSSMMTVDPQQRPHIPVLLSQLEALQPPAPGQHTTQI | cellular response to transforming growth factor beta stimulus positive regulation of transcription by RNA polymerase II protein autophosphorylation protein phosphorylation cytoplasm; cytosol; Golgi apparatus; Golgi-associated vesicle; nucleoplasm; perinuclear region of cytoplasm; plasma membrane ATP binding non-membran... |
cellular response to cAMP cellular response to cGMP potassium ion import across plasma membrane potassium ion transmembrane transport regulation of membrane depolarization regulation of membrane potential sodium ion import across plasma membrane sodium ion transmembrane transport | axon; dendrite; dendrite membrane; dendritic shaft; HCN channel complex; membrane; neuronal cell body; plasma membrane; somatodendritic compartment | cAMP binding identical protein binding intracellular cAMP-activated cation channel activity molecular adaptor activity PDZ domain binding protein-containing complex binding voltage-gated potassium channel activity voltage-gated sodium channel activity | Mus musculus | 3D-structure cAMP cAMP-binding Cell membrane Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Methylation Nucleotide-binding Phosphoprotein Potassium Potassium channel Potassium transport Reference proteome Sodium Sodium channel Sodium transport Transmembrane Transmembrane helix Transport Voltag... | MDARGGGGRP | MDARGGGGRPGDSPGTTPAPGPPPPPPPPAPPQPQPPPAPPPNPTTPSHPESADEPGPRARLCSRDSACTPGAAKGGANGECGRGEPQCSPEGPARGPKVSFSCRGAASGPSAAEEAGSEEAGPAGEPRGSQASFLQRQFGALLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIEDNTEIILDPEKIKKKYLRTWFVVDFVSSIPVDYIFLIVEKGIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYI... | cellular response to cAMP cellular response to cGMP potassium ion import across plasma membrane potassium ion transmembrane transport regulation of membrane depolarization regulation of membrane potential sodium ion import across plasma membrane sodium ion transmembrane transport axon; dendrite; dendrite membrane; dend... |
apical protein localization cellular response to cAMP general adaptation syndrome, behavioral process negative regulation of action potential neuronal action potential positive regulation of membrane hyperpolarization potassium ion transmembrane transport protein homotetramerization regulation of membrane depolarizatio... | apical dendrite; axon; axon terminus; basolateral plasma membrane; cell surface; dendrite; dendrite membrane; dendritic shaft; glutamatergic synapse; HCN channel complex; neuronal cell body; plasma membrane; postsynaptic membrane; presynaptic active zone membrane; somatodendritic compartment | cAMP binding identical protein binding intracellular cAMP-activated cation channel activity intracellular cAMP-activated cation channel activity involved in regulation of presynaptic membrane potential phosphatidylinositol-3,4,5-trisphosphate binding phosphatidylinositol-4,5-bisphosphate binding voltage-gated monoatomi... | Mus musculus | 3D-structure cAMP cAMP-binding Cell membrane Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Nucleotide-binding Potassium Potassium channel Potassium transport Reference proteome Sodium Sodium channel Sodium transport Transmembrane Transmembrane helix Transport Voltage-gated channel | MEGGGKPNSA | MEGGGKPNSASNSRDDGNSVFPSKAPATGPVAADKRLGTPPGGGAAGKEHGNSVCFKVDGGGGEEPAGSFEDAEGPRRQYGFMQRQFTSMLQPGVNKFSLRMFGSQKAVEKEQERVKTAGFWIIHPYSDFRFYWDLIMLIMMVGNLVIIPVGITFFTEQTTTPWIIFNVASDTVFLLDLIMNFRTGTVNEDSSEIILDPKVIKMNYLKSWFVVDFISSIPVDYIFLIVEKGMDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWV... | apical protein localization cellular response to cAMP general adaptation syndrome, behavioral process negative regulation of action potential neuronal action potential positive regulation of membrane hyperpolarization potassium ion transmembrane transport protein homotetramerization regulation of membrane depolarizatio... |
cellular response to dopamine potassium ion transmembrane transport regulation of membrane depolarization regulation of membrane potential sodium ion transmembrane transport | axon; cone cell pedicle; dendrite; HCN channel complex; membrane; neuronal cell body; plasma membrane | cAMP binding voltage-gated potassium channel activity voltage-gated sodium channel activity | Mus musculus | cAMP cAMP-binding Cell membrane Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Nucleotide-binding Phosphoprotein Potassium Potassium channel Potassium transport Reference proteome Sodium Sodium channel Sodium transport Transmembrane Transmembrane helix Transport Voltage-gated channel | MEEEARPAAG | MEEEARPAAGAGEAATPARETPPAAPAQARAASGGVPESAPEPKRRQLGTLLQPTVNKFSLRVFGSHKAVEIEQERVKSAGAWIIHPYSDFRFYWDLIMLLLMVGNLIVLPVGITFFKEENSPPWIVFNVLSDTFFLLDLVLNFRTGIVVEEGAEILLAPRAIRTRYLRTWFLVDLISSIPVDYIFLVVELEPRLDAEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVSMNRMVNHSWGRQYSHALFKAMSHMLCIGYGQQAPVG... | cellular response to dopamine potassium ion transmembrane transport regulation of membrane depolarization regulation of membrane potential sodium ion transmembrane transport axon; cone cell pedicle; dendrite; HCN channel complex; membrane; neuronal cell body; plasma membrane cAMP binding voltage-gated potassium channel... |
DNA replication DNA replication initiation polar body extrusion after meiotic divisions protein polymerization | chromosome, telomeric region; cytoplasm; cytosol; nuclear origin of replication recognition complex; nucleolus; nucleoplasm; nucleus; origin recognition complex | ATP binding ATP hydrolysis activity DNA replication origin binding nucleotide binding | Mus musculus | ATP-binding DNA replication DNA-binding Methylation Nucleotide-binding Nucleus Reference proteome | MSSRKTKSNA | MSSRKTKSNAHAECLSQVQRILRERFCHHSPHSNLFGVQVQYKHLIELLKRTAIYGESNSVLIVGPRGSGKTTLLNHALKELMEIEVSENVIQVHLNGLLQTNEKIALKEITRQLNLDNVVEDKVFGSFAENLSFLLEALQKGDRTSSCPVIFILDEFDIFAHQKNQTLLYNLFDISQSAQTPVAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFDFPQYLKIFKEQLSLPAEFPDKAFAERWNENVHCLSEDSTVLEVLQKHFSVNKNLQSLHMLLMLALNRVTVSHPFMTSADLMEAQHMCSLDSKANIVHGLSV... | DNA replication DNA replication initiation polar body extrusion after meiotic divisions protein polymerization chromosome, telomeric region; cytoplasm; cytosol; nuclear origin of replication recognition complex; nucleolus; nucleoplasm; nucleus; origin recognition complex ATP binding ATP hydrolysis activity DNA replicat... |
negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II presynapse to nucleus signaling pathway regulation of cell cycle regulation of transcription by RNA polymerase II synaptic vesicle clustering synaptic vesicle endocytosis white fat cell differentiation | cytoplasm; extrinsic component of presynaptic endocytic zone membrane; GABA-ergic synapse; glutamatergic synapse; nucleoplasm; nucleus; presynapse; presynaptic active zone cytoplasmic component; transcription repressor complex | chromatin binding DNA-binding transcription factor binding identical protein binding NAD binding oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor PDZ domain binding protein domain specific binding protein homodimerization activity RNA polymerase II-specific DNA-binding transcription... | Mus musculus | ADP-ribosylation Alternative splicing Cytoplasm Differentiation Direct protein sequencing Isopeptide bond NAD Nucleus Oxidoreductase Phosphoprotein Reference proteome Repressor Transcription Transcription regulation Ubl conjugation | MGSSHLLNKG | MGSSHLLNKGLPLGVRPPIMNGPMHPRPLVALLDGRDCTVEMPILKDVATVAFCDAQSTQEIHEKVLNEAVGALMYHTITLTREDLEKFKALRIIVRIGSGFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRTTWLHQALREGTRVQSVEQIREVASGAARIRGETLGIIGLGRVGQAVALRAKAFGFNVLFYDPYLSDGIERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYS... | negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II presynapse to nucleus signaling pathway regulation of cell cycle regulation of transcription by RNA polymerase II synaptic vesicle clustering synaptic vesicle endocytosis white fat cell differentiation cytoplasm... |
cell surface receptor signaling pathway innate immune response | intracellular membrane-bounded organelle; plasma membrane | carbohydrate binding | Mus musculus | 3D-structure Cell membrane Disulfide bond Glycoprotein Immunity Innate immunity Lectin Membrane Phosphoprotein Receptor Reference proteome Signal-anchor Transmembrane Transmembrane helix | MADSSIYSTL | MADSSIYSTLELPEAPQVQDESRWKLKAVLHRPHLSRFAMVALGLLTVILMSLLMYQRILCCGSKDSTCSHCPSCPILWTRNGSHCYYFSMEKKDWNSSLKFCADKGSHLLTFPDNQGVKLFGEYLGQDFYWIGLRNIDGWRWEGGPALSLRILTNSLIQRCGAIHRNGLQASSCEVALQWICKKVLY | cell surface receptor signaling pathway innate immune response intracellular membrane-bounded organelle; plasma membrane carbohydrate binding Mus musculus 3D-structure Cell membrane Disulfide bond Glycoprotein Immunity Innate immunity Lectin Membrane Phosphoprotein Receptor Reference proteome Signal-anchor Transmembran... |
cellular response to hormone stimulus G protein-coupled receptor signaling pathway negative regulation of cell population proliferation negative regulation of urine volume positive regulation of blood pressure positive regulation of cell population proliferation positive regulation of gene expression positive regulatio... | endocytic vesicle; endosome; perinuclear region of cytoplasm; plasma membrane | peptide binding signaling receptor activity vasopressin receptor activity | Mus musculus | Cell membrane G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MILVSTTSAV | MILVSTTSAVPGALSSPSSPSNSSQEELLDDRDPLLVRAELALLSTIFVAVALSNGLVLGALIRRGRRGRWAPMHVFISHLCLADLAVALFQVLPQLAWDATDRFHGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLLLSLPQLFIFAQRDVGNGSGVFDCWARFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHASLVPGPSERAGRRRRGHRTGSPSEGAHVSAAMAKTVRMTLVIVIVYVLCWAPFFLVQLWAAWDPEAPLERPPFVLLMLLASLNSCT... | cellular response to hormone stimulus G protein-coupled receptor signaling pathway negative regulation of cell population proliferation negative regulation of urine volume positive regulation of blood pressure positive regulation of cell population proliferation positive regulation of gene expression positive regulatio... |
cell morphogenesis cell population proliferation fertilization germ cell development glycosphingolipid metabolic process homeostasis of number of cells Leydig cell differentiation microtubule bundle formation microtubule cytoskeleton organization nucleus organization organ growth protein localization to plasma membrane... | axon; basolateral plasma membrane; cytosol; microtubule; microtubule cytoskeleton; perinuclear region of cytoplasm; plasma membrane | signaling receptor binding | Mus musculus | Acetylation Alternative splicing Cell membrane Coiled coil Cytoplasm Cytoskeleton Isopeptide bond Membrane Microtubule Phosphoprotein Reference proteome Ubl conjugation | MAEQGAGGDG | MAEQGAGGDGHRGGDGATHSDPASDGYKVQEKRTAPSRPTSTVSGQTSNHSGNKPDPPPVLRVDDRQRLARERREEREKQLAARETVWLEREERARQHYERHLEARKKKLEDQRLKEERRRAAVEEKRRQRLEEDKERHEAVVRRTMERSQKPRQKSNRWSWGSPLHGSSSIHSGDPDRRSVSTMNLSKHVDPVISKRLSSSSATLLNSPDRARRLQLSPWESSVVSRLLTPTHSFLARSKSTAALSGDTASCSPIIMPFKAAHSRNPVDRPKLFVTPPEGSARRRTIHGLASHKREREREHVPFHVSPGARRTLSPSNL... | cell morphogenesis cell population proliferation fertilization germ cell development glycosphingolipid metabolic process homeostasis of number of cells Leydig cell differentiation microtubule bundle formation microtubule cytoskeleton organization nucleus organization organ growth protein localization to plasma membrane... |
androgen metabolic process brain development cell differentiation cholesterol biosynthetic process embryonic organ development embryonic skeletal system development estrogen biosynthetic process nervous system development | endoplasmic reticulum; endoplasmic reticulum membrane | 3-keto sterol reductase activity 5alpha-androstane-3beta,17beta-diol dehydrogenase activity estradiol 17-beta-dehydrogenase activity prolactin receptor binding | Mus musculus | Endoplasmic reticulum Glycoprotein Lipid biosynthesis Lipid metabolism Membrane NAD NADP Oxidoreductase Reference proteome Steroid biosynthesis Transmembrane Transmembrane helix | MRKVVLITGA | MRKVVLITGASSGIGLALCGRLLAEDDDLHLCLACRNLSKARAVRDTLLASHPSAEVSIVQMDVSSLQSVVRGAEEVKQKFQRLDYLYLNAGILPNPQFNLKAFFCGIFSRNVIHMFTTAEGILTQNDSVTADGLQEVFETNLFGHFILIRELEPLLCHADNPSQLIWTSSRNAKKANFSLEDIQHSKGPEPYSSSKYATDLLNVALNRNFNQKGLYSSVMCPGVVMTNMTYGILPPFIWTLLLPIMWLLRFFVNALTVTPYNGAEALVWLFHQKPESLNPLTKYASATSGFGTNYVTGQKMDIDEDTAEKFYEVLLELE... | androgen metabolic process brain development cell differentiation cholesterol biosynthetic process embryonic organ development embryonic skeletal system development estrogen biosynthetic process nervous system development endoplasmic reticulum; endoplasmic reticulum membrane 3-keto sterol reductase activity 5alpha-andr... |
autophagosome-lysosome fusion endosomal transport positive regulation of autophagosome maturation protein transport regulation of endosome organization signal transduction substrate localization to autophagosome | cytoplasm; cytosol; early endosome; early endosome membrane; endosome; endosome membrane; membrane | clathrin binding clathrin heavy chain binding myosin VI binding phosphatidylinositol-5-phosphate binding polyubiquitin modification-dependent protein binding ubiquitin binding | Mus musculus | Acetylation Alternative splicing Cytoplasm Endosome Isopeptide bond Membrane Phosphoprotein Protein transport Reference proteome Transport Ubl conjugation | MDFLLGNPFS | MDFLLGNPFSSPVGQRIEKATDGSLQSEDWALNMEICDIINETEEGPKDAFRAVKKRIMGNKNFHEVMLALTVLETCVKNCGHRFHVLVANQDFVENVLVRTILPKNNPPTIVHDKVLNLIQSWADAFRSSPDLTGVVAVYEDLRRKGLEFPMTDLDMLSPIHTPQRTVFNSETPSRQNSVSSNTSQRGDLSQHATPLPTPAVLPGDSPITPTPEQIGKLRSELEMVSGNVRVMSEMLTELVPTQVEPADLELLQELNRTCRAMQQRILELIPRISNEQLTEELLMINDNLNNVFLRHERFERFRTGQTAKASSEAELAT... | autophagosome-lysosome fusion endosomal transport positive regulation of autophagosome maturation protein transport regulation of endosome organization signal transduction substrate localization to autophagosome cytoplasm; cytosol; early endosome; early endosome membrane; endosome; endosome membrane; membrane clathrin ... |
modification of postsynaptic actin cytoskeleton negative regulation of cell communication by electrical coupling negative regulation of protein import into nucleus postsynapse to nucleus signaling pathway regulation of postsynapse to nucleus signaling pathway regulation of synaptic plasticity visual perception | axon; cytoplasm; cytoskeleton; dendrite; glutamatergic synapse; Golgi membrane; neuronal cell body; nucleus; perinuclear region of cytoplasm; plasma membrane; postsynaptic density; postsynaptic density, intracellular component; protein-containing complex; secretory granule; subplasmalemmal coating | calcium channel regulator activity calcium ion binding calcium-dependent protein binding identical protein binding nuclear localization sequence binding protein domain specific binding transmembrane transporter binding type 3 metabotropic glutamate receptor binding | Rattus norvegicus | Alternative splicing Calcium Cytoplasm Cytoskeleton Developmental protein Metal-binding Phosphoprotein Reference proteome Repeat Sensory transduction Vision | MSSHIAKSES | MSSHIAKSESKTSLLKAAAASGGSRAPRHSSARDPGLRGRRLPGPCPDSPATCGDPSSRRPLCRPVPRDEGARGSRRGLPQAHCRPRETLPPARGRDGEERGLAPALSLRGSLRSRGRGDPAPAGTPEADPFLHQLRPMLSSAFGQDRSLRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHVDFDDFVELMGPKLLAETADMIGVKELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEEFVRMMSR | modification of postsynaptic actin cytoskeleton negative regulation of cell communication by electrical coupling negative regulation of protein import into nucleus postsynapse to nucleus signaling pathway regulation of postsynapse to nucleus signaling pathway regulation of synaptic plasticity visual perception axon; cy... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.