Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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autophagosome assembly autophagosome maturation autophagy cell cycle cell division cellular response to glucose starvation cellular response to starvation early endosome to late endosome transport endocytosis endosome organization macroautophagy phosphatidylinositol 3-kinase/protein kinase B signal transduction phosphatidylinositol phosphate biosynthetic process phosphatidylinositol-3-phosphate biosynthetic process phosphatidylinositol-mediated signaling phosphorylation protein localization to phagophore assembly site protein processing regulation of autophagy regulation of cytokinesis regulation of macroautophagy response to leucine | autolysosome; axoneme; cytoplasm; cytosol; endosome; late endosome; membrane; midbody; peroxisome; phagocytic vesicle; phagophore assembly site; phosphatidylinositol 3-kinase complex, class III; phosphatidylinositol 3-kinase complex, class III, type I; phosphatidylinositol 3-kinase complex, class III, type II | 1-phosphatidylinositol-3-kinase activity ATP binding kinase activity protein kinase activity | Rattus norvegicus | ATP-binding Autophagy Cell cycle Cell division Cytoplasmic vesicle Endosome Kinase Lipid metabolism Manganese Nucleotide-binding Phosphoprotein Reference proteome Transferase Ubl conjugation | MGEAEKFHYI | MGEAEKFHYIYSCDLDINVQLKIGSLEGKREQKSYKAVLEDPMLKFSGLYQETCSDLYVTCQVFAEGKPLALPVRTSYKPFSTRWNWNEWLKLPVKYPDLPRNAQVALTIWDVYGPGRAVPVGGTTVSLFGKYGMFRQGMHDLKVWPNVEADGSEPTRTPGRTSSTLSEDQMSRLAKLTKAHRQGHMVKVDWLDRLTFREIEMINESEKRSSNFMYLMVEFRCVKCDDKEYGIVYYEKDGDESSPILTSFELVKVPDPQMSMENLVESKHHKLARSLRSGPSDHDLKPNATTRDQLNIIVSYPPTKQLTYEEQDLVWKFRYYLTNQEKALTKFLKCVNWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRRYAVARLRQADDEDLLMYLLQLVQALKYENFDDIKNGLEPTKKDSQASVSESLSSSGVSSADIDSSQIITNPLPPVASPPPASKSKEVSDGENLEQDLCTFLISRACKNSTLANYLYWYVIVECEDQDTQQRDPKTHEMYLNVMRRFSQALLKGDKSVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQALLGDNEKMNLSDVELIPLPLEPQVKIRGIIPETATLFKSALMPAQLFFKTEDGGKYPVIFKHGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFMQFIQSVPVAEVLDTEGSIQNFFRKYAPSETGPNGISAEVMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKTGKLFHIDFGYILGRDPKPLPPPMKLNKEMVEGMGGTQSEQYQEFRKQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHYMQSLIDESVHALFAAVVEQIHKFAQYWRK | autophagosome assembly autophagosome maturation autophagy cell cycle cell division cellular response to glucose starvation cellular response to starvation early endosome to late endosome transport endocytosis endosome organization macroautophagy phosphatidylinositol 3-kinase/protein kinase B signal transduction phosphatidylinositol phosphate biosynthetic process phosphatidylinositol-3-phosphate biosynthetic process phosphatidylinositol-mediated signaling phosphorylation protein localization to phagophore assembly site protein processing regulation of autophagy regulation of cytokinesis regulation of macroautophagy response to leucine autolysosome; axoneme; cytoplasm; cytosol; endosome; late endosome; membrane; midbody; peroxisome; phagocytic vesicle; phagophore assembly site; phosphatidylinositol 3-kinase complex, class III; phosphatidylinositol 3-kinase complex, class III, type I; phosphatidylinositol 3-kinase complex, class III, type II 1-phosphatidylinositol-3-kinase activity ATP binding kinase activity protein kinase activity Rattus norvegicus ATP-binding Autophagy Cell cycle Cell division Cytoplasmic vesicle Endosome Kinase Lipid metabolism Manganese Nucleotide-binding Phosphoprotein Reference proteome Transferase Ubl conjugation MGEAEKFHYI MGEAEKFHYIYSCDLDINVQLKIGSLEGKREQKSYKAVLEDPMLKFSGLYQETCSDLYVTCQVFAEGKPLALPVRTSYKPFSTRWNWNEWLKLPVKYPDLPRNAQVALTIWDVYGPGRAVPVGGTTVSLFGKYGMFRQGMHDLKVWPNVEADGSEPTRTPGRTSSTLSEDQMSRLAKLTKAHRQGHMVKVDWLDRLTFREIEMINESEKRSSNFMYLMVEFRCVKCDDKEYGIVYYEKDGDESSPILTSFELVKVPDPQMSMENLVESKHHKLARSLRSGPSDHDLKPNATTRDQLNIIVSYPPTKQLTYEEQDLVWKFRYYLTNQEKALTKFLKCVNWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRRYAVARLRQADDEDLLMYLLQLVQALKYENFDDIKNGLEPTKKDSQASVSESLSSSGVSSADIDSSQIITNPLPPVASPPPASKSKEVSDGENLEQDLCTFLISRACKNSTLANYLYWYVIVECEDQDTQQRDPKTHEMYLNVMRRFSQALLKGDKSVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQALLGDNEKMNLSDVELIPLPLEPQVKIRGIIPETATLFKSALMPAQLFFKTEDGGKYPVIFKHGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFMQFIQSVPVAEVLDTEGSIQNFFRKYAPSETGPNGISAEVMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKTGKLFHIDFGYILGRDPKPLPPPMKLNKEMVEGMGGTQSEQYQEFRKQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHYMQSLIDESVHALFAAVVEQIHKFAQYWRK |
apoptotic process apoptotic signaling pathway cellular response to type II interferon chromatin organization intracellular signal transduction negative regulation of translation neuron differentiation positive regulation of apoptotic process positive regulation of canonical Wnt signaling pathway positive regulation of cell migration positive regulation of extrinsic apoptotic signaling pathway in absence of ligand protein autophosphorylation regulation of actin cytoskeleton organization regulation of cell shape regulation of focal adhesion assembly regulation of mitotic cell cycle regulation of myosin II filament organization | actin filament; chromosome, centromeric region; cytoplasm; membrane raft; microtubule organizing center; nucleus; PML body | ATP binding DNA-binding transcription factor binding identical protein binding kinase activity leucine zipper domain binding protein homodimerization activity protein serine kinase activity protein serine/threonine kinase activity small GTPase binding | Rattus norvegicus | Activator Alternative splicing Apoptosis ATP-binding Centromere Chromatin regulator Chromosome Cytoplasm Cytoskeleton Kinase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transcription Transcription regulation Transferase Ubl conjugation | MSTFRQEDVE | MSTFRQEDVEDHYEMGEELGSGQFAIVRKCQQKGTGMEYAAKFIKKRRLPSSRRGVSREEIEREVSILREIRHPNIITLHDVFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSKRIAHFDLKPENIMLLDKHAASPRIKLIDFGIAHRIEAGSEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSSTSELAKDFIRRLLVKDPKRRMTIAQSLEHSWIKVRRREDGARKPERRRLRAARLREYSLKSHSSMPRNTSYASFERFSRVLEDVAAAEQGLRELQRGRRQCRERVCALRVAAEQREARCRDGSAGLGRDLRRLRTELGRTEALRTRAQEEARAALLGAGGLKRRLCRLENRYDALAAQVAAEVQFVRDLVRALEQERLQAECGVR | apoptotic process apoptotic signaling pathway cellular response to type II interferon chromatin organization intracellular signal transduction negative regulation of translation neuron differentiation positive regulation of apoptotic process positive regulation of canonical Wnt signaling pathway positive regulation of cell migration positive regulation of extrinsic apoptotic signaling pathway in absence of ligand protein autophosphorylation regulation of actin cytoskeleton organization regulation of cell shape regulation of focal adhesion assembly regulation of mitotic cell cycle regulation of myosin II filament organization actin filament; chromosome, centromeric region; cytoplasm; membrane raft; microtubule organizing center; nucleus; PML body ATP binding DNA-binding transcription factor binding identical protein binding kinase activity leucine zipper domain binding protein homodimerization activity protein serine kinase activity protein serine/threonine kinase activity small GTPase binding Rattus norvegicus Activator Alternative splicing Apoptosis ATP-binding Centromere Chromatin regulator Chromosome Cytoplasm Cytoskeleton Kinase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transcription Transcription regulation Transferase Ubl conjugation MSTFRQEDVE MSTFRQEDVEDHYEMGEELGSGQFAIVRKCQQKGTGMEYAAKFIKKRRLPSSRRGVSREEIEREVSILREIRHPNIITLHDVFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSKRIAHFDLKPENIMLLDKHAASPRIKLIDFGIAHRIEAGSEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSSTSELAKDFIRRLLVKDPKRRMTIAQSLEHSWIKVRRREDGARKPERRRLRAARLREYSLKSHSSMPRNTSYASFERFSRVLEDVAAAEQGLRELQRGRRQCRERVCALRVAAEQREARCRDGSAGLGRDLRRLRTELGRTEALRTRAQEEARAALLGAGGLKRRLCRLENRYDALAAQVAAEVQFVRDLVRALEQERLQAECGVR |
cellular response to lipopolysaccharide collagen catabolic process endodermal cell differentiation extracellular matrix organization ossification positive regulation of microglial cell activation positive regulation of neuroinflammatory response positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor-mediated signaling pathway protein catabolic process proteolysis | extracellular matrix; extracellular space | calcium ion binding endopeptidase activity metalloendopeptidase activity metallopeptidase activity peptidase activity serine-type endopeptidase activity tumor necrosis factor binding zinc ion binding | Rattus norvegicus | Calcium Collagen degradation Disulfide bond Extracellular matrix Glycoprotein Hydrolase Metal-binding Metalloprotease Protease Reference proteome Repeat Secreted Signal Zinc Zymogen | MLHLKTLPFL | MLHLKTLPFLFFFHTQLATALPVPPEHLEEKNMKTAENYLRKFYHLPSNQFRSARNATMIAEKLKEMQRFFGLPETGKPDAATIEIMEKPRCGVPDSGDFLLTPGSPKWTHTNLTYRIINHTPQMSKAEVKTEIEKAFKIWSVPSTLTFTETLEGEADINIAFVSRDHGDNSPFDGPNGILAHAFQPGRGIGGDAHFDSEETWTQDSKNYNLFLVAAHEFGHSLGLSHSTDPGALMYPNYAYREPSTYSLPQDDINGIQTIYGPSDNPVQPTGPSTPTACDPHLRFDAATTLRGEIYFFKDKYFWRRHPQLRTVDLNFISLFWPFLPNGLQAAYEDFDRDLVFLFKGRQYWALSAYDLQQGYPRDISNYGFPRSVQAIDAAVSYNGKTYFFVNNQCWRYDNQRRSMDPGYPTSIASVFPGINCRIDAVFQQDSFFLFFSGPQYFAFNLVSRRVTRVARSNLWLNCP | cellular response to lipopolysaccharide collagen catabolic process endodermal cell differentiation extracellular matrix organization ossification positive regulation of microglial cell activation positive regulation of neuroinflammatory response positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor-mediated signaling pathway protein catabolic process proteolysis extracellular matrix; extracellular space calcium ion binding endopeptidase activity metalloendopeptidase activity metallopeptidase activity peptidase activity serine-type endopeptidase activity tumor necrosis factor binding zinc ion binding Rattus norvegicus Calcium Collagen degradation Disulfide bond Extracellular matrix Glycoprotein Hydrolase Metal-binding Metalloprotease Protease Reference proteome Repeat Secreted Signal Zinc Zymogen MLHLKTLPFL MLHLKTLPFLFFFHTQLATALPVPPEHLEEKNMKTAENYLRKFYHLPSNQFRSARNATMIAEKLKEMQRFFGLPETGKPDAATIEIMEKPRCGVPDSGDFLLTPGSPKWTHTNLTYRIINHTPQMSKAEVKTEIEKAFKIWSVPSTLTFTETLEGEADINIAFVSRDHGDNSPFDGPNGILAHAFQPGRGIGGDAHFDSEETWTQDSKNYNLFLVAAHEFGHSLGLSHSTDPGALMYPNYAYREPSTYSLPQDDINGIQTIYGPSDNPVQPTGPSTPTACDPHLRFDAATTLRGEIYFFKDKYFWRRHPQLRTVDLNFISLFWPFLPNGLQAAYEDFDRDLVFLFKGRQYWALSAYDLQQGYPRDISNYGFPRSVQAIDAAVSYNGKTYFFVNNQCWRYDNQRRSMDPGYPTSIASVFPGINCRIDAVFQQDSFFLFFSGPQYFAFNLVSRRVTRVARSNLWLNCP |
axon guidance cell adhesion dendrite self-avoidance homophilic cell adhesion via plasma membrane adhesion molecules plasma membrane lactate transport | axon; plasma membrane; synapse | cell-cell adhesion mediator activity | Rattus norvegicus | Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Immunoglobulin domain Membrane Phosphoprotein Reference proteome Repeat Signal Synapse Transmembrane Transmembrane helix | MRSHTGLRAL | MRSHTGLRALVAPGCSLLLLYLLAATRPDRAVGDPADSAFTSLPVREEMMAKYANLSLETYNISLTEQTRVSEQNITLERPSHLELECTFTATEDVMSMNVTWKKDDALLETTDGFNTTKMGDTLYSQYRFTVFNSKQMGKYSCFLGEELRGTFNIRVPKVHGKNKPLITYVGDSTVLKCECQNCLPLNWTWYMSNGTAQVPIDVHVNDKFDINGSYANETKLKVKHLLEEDGGSYWCRAAFPLGESEEHIKLVVLSFMVPLKPFLAIIAEVILLVAIILLCEVYTQKKKNDPDDGKEFEQIEQLKSDDSNGIENNVPRYRKTDSGDQ | axon guidance cell adhesion dendrite self-avoidance homophilic cell adhesion via plasma membrane adhesion molecules plasma membrane lactate transport axon; plasma membrane; synapse cell-cell adhesion mediator activity Rattus norvegicus Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Immunoglobulin domain Membrane Phosphoprotein Reference proteome Repeat Signal Synapse Transmembrane Transmembrane helix MRSHTGLRAL MRSHTGLRALVAPGCSLLLLYLLAATRPDRAVGDPADSAFTSLPVREEMMAKYANLSLETYNISLTEQTRVSEQNITLERPSHLELECTFTATEDVMSMNVTWKKDDALLETTDGFNTTKMGDTLYSQYRFTVFNSKQMGKYSCFLGEELRGTFNIRVPKVHGKNKPLITYVGDSTVLKCECQNCLPLNWTWYMSNGTAQVPIDVHVNDKFDINGSYANETKLKVKHLLEEDGGSYWCRAAFPLGESEEHIKLVVLSFMVPLKPFLAIIAEVILLVAIILLCEVYTQKKKNDPDDGKEFEQIEQLKSDDSNGIENNVPRYRKTDSGDQ |
keratinocyte proliferation memory neuron projection morphogenesis proteolysis regulation of synapse organization response to wounding synapse organization | cytoplasm; extracellular space; secretory granule; serine protease inhibitor complex | peptidase activity serine-type endopeptidase activity | Rattus norvegicus | Cytoplasm Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Secreted Serine protease Signal Zymogen | MGRPPPCAIQ | MGRPPPCAIQTWILLFLLMGAWAGLTRAQGSKILEGQECKPHSQPWQTALFQGERLVCGGVLVGDRWVLTAAHCKKDKYSVRLGDHSLQKRDEPEQEIQVARSIQHPCFNSSNPEDHSHDIMLIRLQNSANLGDKVKPIELANLCPKVGQKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERAYPGKITEGMVCAGSSNGADTCQGDSGGPLVCNGVLQGITTWGSDPCGKPEKPGVYTKICRYTNWIKKTMGKRD | keratinocyte proliferation memory neuron projection morphogenesis proteolysis regulation of synapse organization response to wounding synapse organization cytoplasm; extracellular space; secretory granule; serine protease inhibitor complex peptidase activity serine-type endopeptidase activity Rattus norvegicus Cytoplasm Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Secreted Serine protease Signal Zymogen MGRPPPCAIQ MGRPPPCAIQTWILLFLLMGAWAGLTRAQGSKILEGQECKPHSQPWQTALFQGERLVCGGVLVGDRWVLTAAHCKKDKYSVRLGDHSLQKRDEPEQEIQVARSIQHPCFNSSNPEDHSHDIMLIRLQNSANLGDKVKPIELANLCPKVGQKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERAYPGKITEGMVCAGSSNGADTCQGDSGGPLVCNGVLQGITTWGSDPCGKPEKPGVYTKICRYTNWIKKTMGKRD |
cytokine-mediated signaling pathway immunoglobulin mediated immune response negative regulation of immunoglobulin production negative regulation of mast cell degranulation | external side of plasma membrane; extracellular region; receptor complex | cytokine binding cytokine receptor activity | Mus musculus | Alternative splicing Disulfide bond Glycoprotein Membrane Receptor Reference proteome Repeat Secreted Signal Transmembrane Transmembrane helix | MAFVHIRCLC | MAFVHIRCLCFILLCTITGYSLEIKVNPPQDFEILDPGLLGYLYLQWKPPVVIEKFKGCTLEYELKYRNVDSDSWKTIITRNLIYKDGFDLNKGIEGKIRTHLSEHCTNGSEVQSPWIEASYGISDEGSLETKIQDMKCIYYNWQYLVCSWKPGKTVYSDTNYTMFFWYEGLDHALQCADYLQHDEKNVGCKLSNLDSSDYKDFFICVNGSSKLEPIRSSYTVFQLQNIVKPLPPEFLHISVENSIDIRMKWSTPGGPIPPRCYTYEIVIREDDISWESATDKNDMKLKRRANESEDLCFFVRCKVNIYCADDGIWSEWSEEECWEGYTGPDSKIIFIVPVCLFFIFLLLLLCLIVEKEEPEPTLSLHVDLNKEVCAYEDTLC | cytokine-mediated signaling pathway immunoglobulin mediated immune response negative regulation of immunoglobulin production negative regulation of mast cell degranulation external side of plasma membrane; extracellular region; receptor complex cytokine binding cytokine receptor activity Mus musculus Alternative splicing Disulfide bond Glycoprotein Membrane Receptor Reference proteome Repeat Secreted Signal Transmembrane Transmembrane helix MAFVHIRCLC MAFVHIRCLCFILLCTITGYSLEIKVNPPQDFEILDPGLLGYLYLQWKPPVVIEKFKGCTLEYELKYRNVDSDSWKTIITRNLIYKDGFDLNKGIEGKIRTHLSEHCTNGSEVQSPWIEASYGISDEGSLETKIQDMKCIYYNWQYLVCSWKPGKTVYSDTNYTMFFWYEGLDHALQCADYLQHDEKNVGCKLSNLDSSDYKDFFICVNGSSKLEPIRSSYTVFQLQNIVKPLPPEFLHISVENSIDIRMKWSTPGGPIPPRCYTYEIVIREDDISWESATDKNDMKLKRRANESEDLCFFVRCKVNIYCADDGIWSEWSEEECWEGYTGPDSKIIFIVPVCLFFIFLLLLLCLIVEKEEPEPTLSLHVDLNKEVCAYEDTLC |
actomyosin structure organization cell adhesion cell-cell adhesion cellular response to mechanical stimulus epithelial cell differentiation establishment of endothelial intestinal barrier intestinal absorption leukocyte cell-cell adhesion memory T cell extravasation negative regulation of stress fiber assembly positive regulation of blood pressure positive regulation of establishment of endothelial barrier positive regulation of platelet aggregation positive regulation of Rho protein signal transduction protein localization to bicellular tight junction protein localization to plasma membrane regulation of actin cytoskeleton organization regulation of bicellular tight junction assembly regulation of cell shape regulation of cytokine production regulation of cytoskeleton organization regulation of membrane permeability | bicellular tight junction; cell-cell junction; plasma membrane; protein-containing complex; slit diaphragm; tight junction | integrin binding PDZ domain binding protein homodimerization activity | Mus musculus | 3D-structure Cell junction Cell membrane Disulfide bond Glycoprotein Immunoglobulin domain Membrane Phosphoprotein Reference proteome Repeat Signal Tight junction Transmembrane Transmembrane helix | MGTEGKAGRK | MGTEGKAGRKLLFLFTSMILGSLVQGKGSVYTAQSDVQVPENESIKLTCTYSGFSSPRVEWKFVQGSTTALVCYNSQITAPYADRVTFSSSGITFSSVTRKDNGEYTCMVSEEGGQNYGEVSIHLTVLVPPSKPTISVPSSVTIGNRAVLTCSEHDGSPPSEYSWFKDGISMLTADAKKTRAFMNSSFTIDPKSGDLIFDPVTAFDSGEYYCQAQNGYGTAMRSEAAHMDAVELNVGGIVAAVLVTLILLGLLIFGVWFAYSRGYFERTKKGTAPGKKVIYSQPSTRSEGEFKQTSSFLV | actomyosin structure organization cell adhesion cell-cell adhesion cellular response to mechanical stimulus epithelial cell differentiation establishment of endothelial intestinal barrier intestinal absorption leukocyte cell-cell adhesion memory T cell extravasation negative regulation of stress fiber assembly positive regulation of blood pressure positive regulation of establishment of endothelial barrier positive regulation of platelet aggregation positive regulation of Rho protein signal transduction protein localization to bicellular tight junction protein localization to plasma membrane regulation of actin cytoskeleton organization regulation of bicellular tight junction assembly regulation of cell shape regulation of cytokine production regulation of cytoskeleton organization regulation of membrane permeability bicellular tight junction; cell-cell junction; plasma membrane; protein-containing complex; slit diaphragm; tight junction integrin binding PDZ domain binding protein homodimerization activity Mus musculus 3D-structure Cell junction Cell membrane Disulfide bond Glycoprotein Immunoglobulin domain Membrane Phosphoprotein Reference proteome Repeat Signal Tight junction Transmembrane Transmembrane helix MGTEGKAGRK MGTEGKAGRKLLFLFTSMILGSLVQGKGSVYTAQSDVQVPENESIKLTCTYSGFSSPRVEWKFVQGSTTALVCYNSQITAPYADRVTFSSSGITFSSVTRKDNGEYTCMVSEEGGQNYGEVSIHLTVLVPPSKPTISVPSSVTIGNRAVLTCSEHDGSPPSEYSWFKDGISMLTADAKKTRAFMNSSFTIDPKSGDLIFDPVTAFDSGEYYCQAQNGYGTAMRSEAAHMDAVELNVGGIVAAVLVTLILLGLLIFGVWFAYSRGYFERTKKGTAPGKKVIYSQPSTRSEGEFKQTSSFLV |
behavioral response to cocaine calcium-mediated signaling using intracellular calcium source G protein-coupled glutamate receptor signaling pathway negative regulation of calcineurin-NFAT signaling cascade negative regulation of interleukin-2 production regulation of G protein-coupled receptor signaling pathway regulation of store-operated calcium entry sensory perception of sound | apical part of cell; cytoplasm; dendrite; glutamatergic synapse; intracellular organelle; neuronal cell body; plasma membrane; postsynaptic density; stereocilium tip | actin binding G protein-coupled glutamate receptor binding glutamate receptor binding identical protein binding protein domain specific binding protein-containing complex binding synaptic receptor adaptor activity | Rattus norvegicus | Alternative splicing Cell membrane Cell projection Coiled coil Cytoplasm Hearing Membrane Reference proteome Synapse | MGEQPIFTTR | MGEQPIFTTRAHVFQIDPSTKKNWVPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINSTITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVREAARLARDKSQEKIETSSNHSQESGCETPSSTQASSVNGTDDEKASHASPADTHLKSENDKLKIALTQSAANVKKWEIELQTLRESNARLTTALQESAASVEQWKRQFSICRDENDRLRSKIEELEEQCGEINREKEKNTQLKRRIEELESEVREKEMELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDKVRSLKTDIEESKYRQRHLKGELKSFLEVLDGKIDDLHDFRRGLSKLGTDN | behavioral response to cocaine calcium-mediated signaling using intracellular calcium source G protein-coupled glutamate receptor signaling pathway negative regulation of calcineurin-NFAT signaling cascade negative regulation of interleukin-2 production regulation of G protein-coupled receptor signaling pathway regulation of store-operated calcium entry sensory perception of sound apical part of cell; cytoplasm; dendrite; glutamatergic synapse; intracellular organelle; neuronal cell body; plasma membrane; postsynaptic density; stereocilium tip actin binding G protein-coupled glutamate receptor binding glutamate receptor binding identical protein binding protein domain specific binding protein-containing complex binding synaptic receptor adaptor activity Rattus norvegicus Alternative splicing Cell membrane Cell projection Coiled coil Cytoplasm Hearing Membrane Reference proteome Synapse MGEQPIFTTR MGEQPIFTTRAHVFQIDPSTKKNWVPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINSTITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVREAARLARDKSQEKIETSSNHSQESGCETPSSTQASSVNGTDDEKASHASPADTHLKSENDKLKIALTQSAANVKKWEIELQTLRESNARLTTALQESAASVEQWKRQFSICRDENDRLRSKIEELEEQCGEINREKEKNTQLKRRIEELESEVREKEMELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDKVRSLKTDIEESKYRQRHLKGELKSFLEVLDGKIDDLHDFRRGLSKLGTDN |
chromatin organization chromatin remodeling innate immune response nucleosome assembly post-translational protein modification stem cell population maintenance | cytoplasm; nucleus; protein-containing complex | calcium ion binding histone arginine deiminase activity histone H3R17 arginine deiminase activity histone H3R2 arginine deiminase activity histone H3R26 arginine deiminase activity histone H3R8 arginine deiminase activity identical protein binding protein-arginine deiminase activity | Rattus norvegicus | Calcium Chromatin regulator Citrullination Cytoplasm Hydrolase Immunity Innate immunity Metal-binding Nucleus Reference proteome Transcription Transcription regulation | MAQGAVIHVA | MAQGAVIHVAPEEPTHAVCVVGTATPLDIRGSAPRGSTSFSITASPEVVVDVIHGPPSKKSTTGASKWPLDPKLEVTLQMKAASSRIDDQKVRISYYGPKTSSTQALLYLTGVELSLSADVTRTGKAKPAPAGKDQSTWTWGPDGHGAILLVNCDKEDPKSSGMDFEDDKVLDNKDLQDMSPMTLSTKTPKDFFDKYQLVLQVPKAKMNKVRVFRATRGKLPSRYKVVLGPQQFSHRLELLGGQHSTDFYVEGLAFPDADFKGLIPLTISLLDKSNPELPEALVFQDTVMFRVAPWIMTPNTQPPQEVYVCRFSDNEDFLKSLATFTKKAKCKLTVCPEEENQDDQWMQDEMEIGYIQAPHKTLPVVFDSPRDRGLKDFPVKRVMGPNFGYVTRGLYRAEVTGLDAFGNLEVSPPVTVRGKEYPLGRILIGSSGYSSSESRDMHQILQDFLGAQQVQAPVRLFSDWLFVGHVDEFLSFVPARGKQGFRLLLSSPRACYQMFQELQTEGHGEASLFEGLKRKRQTISDILSSQKLRDQNAYVESCIDWNREVLKRELGLTEGDIIDIPQLFRIVGNSRGNPKAEAFFPNMVNMLVLGKHLGIPKPFGPIINGRCCLEEKVCSLLEPLGLHCTFINDFYSYHMYHGEVHCGTNVRRKPFAFKWWHMVP | chromatin organization chromatin remodeling innate immune response nucleosome assembly post-translational protein modification stem cell population maintenance cytoplasm; nucleus; protein-containing complex calcium ion binding histone arginine deiminase activity histone H3R17 arginine deiminase activity histone H3R2 arginine deiminase activity histone H3R26 arginine deiminase activity histone H3R8 arginine deiminase activity identical protein binding protein-arginine deiminase activity Rattus norvegicus Calcium Chromatin regulator Citrullination Cytoplasm Hydrolase Immunity Innate immunity Metal-binding Nucleus Reference proteome Transcription Transcription regulation MAQGAVIHVA MAQGAVIHVAPEEPTHAVCVVGTATPLDIRGSAPRGSTSFSITASPEVVVDVIHGPPSKKSTTGASKWPLDPKLEVTLQMKAASSRIDDQKVRISYYGPKTSSTQALLYLTGVELSLSADVTRTGKAKPAPAGKDQSTWTWGPDGHGAILLVNCDKEDPKSSGMDFEDDKVLDNKDLQDMSPMTLSTKTPKDFFDKYQLVLQVPKAKMNKVRVFRATRGKLPSRYKVVLGPQQFSHRLELLGGQHSTDFYVEGLAFPDADFKGLIPLTISLLDKSNPELPEALVFQDTVMFRVAPWIMTPNTQPPQEVYVCRFSDNEDFLKSLATFTKKAKCKLTVCPEEENQDDQWMQDEMEIGYIQAPHKTLPVVFDSPRDRGLKDFPVKRVMGPNFGYVTRGLYRAEVTGLDAFGNLEVSPPVTVRGKEYPLGRILIGSSGYSSSESRDMHQILQDFLGAQQVQAPVRLFSDWLFVGHVDEFLSFVPARGKQGFRLLLSSPRACYQMFQELQTEGHGEASLFEGLKRKRQTISDILSSQKLRDQNAYVESCIDWNREVLKRELGLTEGDIIDIPQLFRIVGNSRGNPKAEAFFPNMVNMLVLGKHLGIPKPFGPIINGRCCLEEKVCSLLEPLGLHCTFINDFYSYHMYHGEVHCGTNVRRKPFAFKWWHMVP |
axon extension axoneme assembly brain development central nervous system projection neuron axonogenesis dendrite morphogenesis hippocampus development intracellular signal transduction layer formation in cerebral cortex neuron migration positive regulation of collateral sprouting positive regulation of endocytosis pyramidal neuron development retina development in camera-type eye | axon; cytoplasm; cytosol; dendrite; growth cone; microtubule; neuron projection; neuronal cell body | microtubule binding protein kinase binding | Mus musculus | Cell projection Cytoplasm Developmental protein Differentiation Microtubule Neurogenesis Phosphoprotein Reference proteome Repeat Ubl conjugation | MELDFGHFDE | MELDFGHFDERDKASRNMRGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEYTKNVNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSAAAGPKASPTPQKTSAKSPGPMRRSKSPADSGNDQDANGTSSSQLSTPKSKQSPISTPTSPGSLRKHKVDLYLPLSLDDSDSLGDSM | axon extension axoneme assembly brain development central nervous system projection neuron axonogenesis dendrite morphogenesis hippocampus development intracellular signal transduction layer formation in cerebral cortex neuron migration positive regulation of collateral sprouting positive regulation of endocytosis pyramidal neuron development retina development in camera-type eye axon; cytoplasm; cytosol; dendrite; growth cone; microtubule; neuron projection; neuronal cell body microtubule binding protein kinase binding Mus musculus Cell projection Cytoplasm Developmental protein Differentiation Microtubule Neurogenesis Phosphoprotein Reference proteome Repeat Ubl conjugation MELDFGHFDE MELDFGHFDERDKASRNMRGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEYTKNVNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSAAAGPKASPTPQKTSAKSPGPMRRSKSPADSGNDQDANGTSSSQLSTPKSKQSPISTPTSPGSLRKHKVDLYLPLSLDDSDSLGDSM |
protein transport signal transduction | cytoplasm; cytosol; early endosome membrane; endocytic vesicle; intracellular membrane-bounded organelle; nucleoplasm | phosphatidylinositol binding ubiquitin binding | Mus musculus | 3D-structure Alternative splicing Cytoplasm Endosome Membrane Phosphoprotein Protein transport Reference proteome SH3 domain Transport | MPLFTANPFE | MPLFTANPFEQDVEKATNEYNTTEDWSLIMDICDRVGSTPSGAKDCLKAIMKRVNHKVPHVALQALTLLGACVANCGKIFHLEVCSRDFATEVRSVIKNKAHPKVCEKLKSLMVEWSEEFQKDPQFSLISATIKSMKEEGVTFPSAGSQTVAAAAKNGTSLNKNKEDEDIAKAIELSLQEQKQQYTETKALYPPAESQLNNKAARRVRALYDFEAVEDNELTFKHGELITVLDDSDANWWQGENHRGTGLFPSNFVTTDLSTEVETATVDKLNVIDDDVEEIKKSEPEPVYIDEGKMDRALQILQSIDPKESKPDSQDLLDLEDVCQQMGPMIDEKLEEIDRKHSELSELNVKVLEALDLYNKLVNEAPVYSVYSKLHPAHYPPAAAGVPVQTYPVQSHGGNYLGHGIHQVSVAQNYNLGPDPMGSLRSLPPNMNSVTAHTVQPPYLSTGQDTVSNPSYMNQSSRLQAAAGTAAYTQPVGMSTDVSSFQNTASGLPQLAGFPVAVPAPVAAQPQASYHQQPLL | protein transport signal transduction cytoplasm; cytosol; early endosome membrane; endocytic vesicle; intracellular membrane-bounded organelle; nucleoplasm phosphatidylinositol binding ubiquitin binding Mus musculus 3D-structure Alternative splicing Cytoplasm Endosome Membrane Phosphoprotein Protein transport Reference proteome SH3 domain Transport MPLFTANPFE MPLFTANPFEQDVEKATNEYNTTEDWSLIMDICDRVGSTPSGAKDCLKAIMKRVNHKVPHVALQALTLLGACVANCGKIFHLEVCSRDFATEVRSVIKNKAHPKVCEKLKSLMVEWSEEFQKDPQFSLISATIKSMKEEGVTFPSAGSQTVAAAAKNGTSLNKNKEDEDIAKAIELSLQEQKQQYTETKALYPPAESQLNNKAARRVRALYDFEAVEDNELTFKHGELITVLDDSDANWWQGENHRGTGLFPSNFVTTDLSTEVETATVDKLNVIDDDVEEIKKSEPEPVYIDEGKMDRALQILQSIDPKESKPDSQDLLDLEDVCQQMGPMIDEKLEEIDRKHSELSELNVKVLEALDLYNKLVNEAPVYSVYSKLHPAHYPPAAAGVPVQTYPVQSHGGNYLGHGIHQVSVAQNYNLGPDPMGSLRSLPPNMNSVTAHTVQPPYLSTGQDTVSNPSYMNQSSRLQAAAGTAAYTQPVGMSTDVSSFQNTASGLPQLAGFPVAVPAPVAAQPQASYHQQPLL |
cellular response to insulin stimulus fatty acid metabolic process long-chain fatty acid metabolic process long-chain fatty-acyl-CoA biosynthetic process positive regulation of long-chain fatty acid import across plasma membrane positive regulation of triglyceride biosynthetic process response to cholesterol response to glucose response to nutrient response to sucrose | endoplasmic reticulum; endoplasmic reticulum membrane; membrane; mitochondrial outer membrane; mitochondrion; plasma membrane | arachidonate-CoA ligase activity ATP binding long-chain fatty acid-CoA ligase activity oleoyl-CoA ligase activity | Rattus norvegicus | Acetylation ATP-binding Cell membrane Endoplasmic reticulum Fatty acid metabolism Ligase Lipid metabolism Magnesium Membrane Mitochondrion Mitochondrion outer membrane Nucleotide-binding Reference proteome Signal-anchor Transmembrane Transmembrane helix | MLFIFNFLFS | MLFIFNFLFSPLPTPALICLLTFGTAIFLWLINRPQPVLPLIDLDNQSVGIEGGARRGAFQKNNDLILYYFSDAKTLYEVFQRGLAVSDNGPCLGYRKPNQPYKWISYKQVSDRAEYLGSCLLHKGYKPSQDQFIGIFAQNRPEWVISELACYTYSMVAVPLYDTLGAEAIIYVINRADISVVICDTPQKATMLIENVEKDLTPGLKTVILMDPFDDDLMKRGEKCGIEMLSLHDAENLGKENFKKPMPPNPEDLSVICFTSGTTGDPKGAMLTHQNIVSNMAAFLKFLEPIFQPTPEDVTISYLPLAHMFERLVQGVIFSCGGKIGFFQGDIRLLPDDMKALKPTVFPTVPRLLNRVYDKVQNEAKTPLKKFLLNLAIISKFNEVRNGIIRRNSLWDKLVFSKIQSSLGGKVRLMITGAAPISTPVLTFFRAAMGCWVFEAYGQTECTAGCSITSPGDWTAGHVGTPVSCNFVKLEDVADMNYFSVNNEGEICIKGNNVFKGYLKDPEKTQEVLDKDGWLHTGDIGRWLPNGTLKIIDRKKNIFKLAQGEYIAPEKIENVYSRSRPILQVFVHGESLRSFLIGVVVPDPESLPSFAAKIGVKGSFEELCQNQCVKKAILEDLQKVGKEGGLKSFEQVKSIFVHPEPFSIENGLLTPTLKAKRVELAKFFQTQIKSLYESIEE | cellular response to insulin stimulus fatty acid metabolic process long-chain fatty acid metabolic process long-chain fatty-acyl-CoA biosynthetic process positive regulation of long-chain fatty acid import across plasma membrane positive regulation of triglyceride biosynthetic process response to cholesterol response to glucose response to nutrient response to sucrose endoplasmic reticulum; endoplasmic reticulum membrane; membrane; mitochondrial outer membrane; mitochondrion; plasma membrane arachidonate-CoA ligase activity ATP binding long-chain fatty acid-CoA ligase activity oleoyl-CoA ligase activity Rattus norvegicus Acetylation ATP-binding Cell membrane Endoplasmic reticulum Fatty acid metabolism Ligase Lipid metabolism Magnesium Membrane Mitochondrion Mitochondrion outer membrane Nucleotide-binding Reference proteome Signal-anchor Transmembrane Transmembrane helix MLFIFNFLFS MLFIFNFLFSPLPTPALICLLTFGTAIFLWLINRPQPVLPLIDLDNQSVGIEGGARRGAFQKNNDLILYYFSDAKTLYEVFQRGLAVSDNGPCLGYRKPNQPYKWISYKQVSDRAEYLGSCLLHKGYKPSQDQFIGIFAQNRPEWVISELACYTYSMVAVPLYDTLGAEAIIYVINRADISVVICDTPQKATMLIENVEKDLTPGLKTVILMDPFDDDLMKRGEKCGIEMLSLHDAENLGKENFKKPMPPNPEDLSVICFTSGTTGDPKGAMLTHQNIVSNMAAFLKFLEPIFQPTPEDVTISYLPLAHMFERLVQGVIFSCGGKIGFFQGDIRLLPDDMKALKPTVFPTVPRLLNRVYDKVQNEAKTPLKKFLLNLAIISKFNEVRNGIIRRNSLWDKLVFSKIQSSLGGKVRLMITGAAPISTPVLTFFRAAMGCWVFEAYGQTECTAGCSITSPGDWTAGHVGTPVSCNFVKLEDVADMNYFSVNNEGEICIKGNNVFKGYLKDPEKTQEVLDKDGWLHTGDIGRWLPNGTLKIIDRKKNIFKLAQGEYIAPEKIENVYSRSRPILQVFVHGESLRSFLIGVVVPDPESLPSFAAKIGVKGSFEELCQNQCVKKAILEDLQKVGKEGGLKSFEQVKSIFVHPEPFSIENGLLTPTLKAKRVELAKFFQTQIKSLYESIEE |
cellular response to cAMP circadian rhythm melatonin biosynthetic process N-terminal protein amino acid acetylation photoperiodism response to calcium ion response to copper ion response to corticosterone response to cytokine response to insulin response to light stimulus response to organic cyclic compound response to prostaglandin E response to zinc ion | cytoplasm; cytosol; perinuclear region of cytoplasm | 14-3-3 protein binding aralkylamine N-acetyltransferase activity arylamine N-acetyltransferase activity | Mus musculus | Acyltransferase Biological rhythms Cytoplasm Melatonin biosynthesis Phosphoprotein Reference proteome Transferase | MLNINSLKPE | MLNINSLKPEALHLPLGTSEFLGCQRRHTLPASEFRCLTPEDATSAFEIEREAFISVSGTCPLYLDEIRHFLTLCPELSLGWFEEGCLVAFIIGSLWDKERLTQESLTLHRPGGRTAHLHVLAVHRTFRQQGKGSVLLWRYLHHLGSQPAVRRAVLMCEDALVPFYEKFGFQAVGPCAITVGSLTFTELQCSLRCHAFLRRNSGC | cellular response to cAMP circadian rhythm melatonin biosynthetic process N-terminal protein amino acid acetylation photoperiodism response to calcium ion response to copper ion response to corticosterone response to cytokine response to insulin response to light stimulus response to organic cyclic compound response to prostaglandin E response to zinc ion cytoplasm; cytosol; perinuclear region of cytoplasm 14-3-3 protein binding aralkylamine N-acetyltransferase activity arylamine N-acetyltransferase activity Mus musculus Acyltransferase Biological rhythms Cytoplasm Melatonin biosynthesis Phosphoprotein Reference proteome Transferase MLNINSLKPE MLNINSLKPEALHLPLGTSEFLGCQRRHTLPASEFRCLTPEDATSAFEIEREAFISVSGTCPLYLDEIRHFLTLCPELSLGWFEEGCLVAFIIGSLWDKERLTQESLTLHRPGGRTAHLHVLAVHRTFRQQGKGSVLLWRYLHHLGSQPAVRRAVLMCEDALVPFYEKFGFQAVGPCAITVGSLTFTELQCSLRCHAFLRRNSGC |
fucosylation glycosphingolipid biosynthetic process Lewis x epitope biosynthetic process N-glycan fucosylation nervous system development neuron differentiation neuronal stem cell division oligosaccharide biosynthetic process polysaccharide biosynthetic process positive regulation of neuron projection development protein glycosylation protein N-linked glycosylation protein O-linked glycosylation regulation of leukocyte cell-cell adhesion regulation of leukocyte tethering or rolling | Golgi apparatus; Golgi membrane; trans-Golgi network; trans-Golgi network membrane | 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity alpha-(1->3)-fucosyltransferase activity protein homodimerization activity | Mus musculus | Disulfide bond Glycoprotein Glycosyltransferase Golgi apparatus Lipid metabolism Membrane Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix | MTSTSKGILR | MTSTSKGILRPFLIVCIILGCFMACLLIYIKPTNSWVFSPMESASSVLKMKNFFSTKTDYFNETTILVWVWPFGQTFDLTSCQAMFNIQGCHLTTDRSLYNKSHAVLIHHRDISWDLTNLPQQARPPFQKWIWMNLESPTHTPQKSGIEHLFNLTLTYRRDSDIQVPYGFLTVSTNPFVFEVPSKEKLVCWVVSNWNPEHARVKYYNELSKSIEIHTYGQAFGEYVNDKNLIPTISTCKFYLSFENSIHKDYITEKLYNAFLAGSVPVVLGPSRENYENYIPADSFIHVEDFNSPSELAKYLKEVDKNNKLYLSYFNWRKDFTVNLPRFWESHACLACDHVKRHQEYKSVGNLEKWFWN | fucosylation glycosphingolipid biosynthetic process Lewis x epitope biosynthetic process N-glycan fucosylation nervous system development neuron differentiation neuronal stem cell division oligosaccharide biosynthetic process polysaccharide biosynthetic process positive regulation of neuron projection development protein glycosylation protein N-linked glycosylation protein O-linked glycosylation regulation of leukocyte cell-cell adhesion regulation of leukocyte tethering or rolling Golgi apparatus; Golgi membrane; trans-Golgi network; trans-Golgi network membrane 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity alpha-(1->3)-fucosyltransferase activity protein homodimerization activity Mus musculus Disulfide bond Glycoprotein Glycosyltransferase Golgi apparatus Lipid metabolism Membrane Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix MTSTSKGILR MTSTSKGILRPFLIVCIILGCFMACLLIYIKPTNSWVFSPMESASSVLKMKNFFSTKTDYFNETTILVWVWPFGQTFDLTSCQAMFNIQGCHLTTDRSLYNKSHAVLIHHRDISWDLTNLPQQARPPFQKWIWMNLESPTHTPQKSGIEHLFNLTLTYRRDSDIQVPYGFLTVSTNPFVFEVPSKEKLVCWVVSNWNPEHARVKYYNELSKSIEIHTYGQAFGEYVNDKNLIPTISTCKFYLSFENSIHKDYITEKLYNAFLAGSVPVVLGPSRENYENYIPADSFIHVEDFNSPSELAKYLKEVDKNNKLYLSYFNWRKDFTVNLPRFWESHACLACDHVKRHQEYKSVGNLEKWFWN |
apoptotic mitochondrial changes mitotic cell cycle mitotic cytokinesis positive regulation of protein kinase activity regulation of cell population proliferation | centrosome; cytoplasm; membrane; midbody; mitochondrion; spindle | protein kinase binding | Mus musculus | Apoptosis Cell cycle Cell division Cytoplasm Cytoskeleton Membrane Mitochondrion Mitosis Reference proteome Signal Transmembrane Transmembrane helix | MLAGAGRRGL | MLAGAGRRGLPRAGHLCWLLCAFTLKLCEAEAPVREEKLSVSTSTSPCWLAEEFVVTEECTPCSNFQIKTTPECGSTGYVEKITCSSSKRNEFKSCRSALLEQHLFWKFEGVVVAVALVFACLVIVRQRQLDRKALEKVRKQIESI | apoptotic mitochondrial changes mitotic cell cycle mitotic cytokinesis positive regulation of protein kinase activity regulation of cell population proliferation centrosome; cytoplasm; membrane; midbody; mitochondrion; spindle protein kinase binding Mus musculus Apoptosis Cell cycle Cell division Cytoplasm Cytoskeleton Membrane Mitochondrion Mitosis Reference proteome Signal Transmembrane Transmembrane helix MLAGAGRRGL MLAGAGRRGLPRAGHLCWLLCAFTLKLCEAEAPVREEKLSVSTSTSPCWLAEEFVVTEECTPCSNFQIKTTPECGSTGYVEKITCSSSKRNEFKSCRSALLEQHLFWKFEGVVVAVALVFACLVIVRQRQLDRKALEKVRKQIESI |
lipid metabolic process protein glycosylation | Golgi membrane | lactosylceramide alpha-2,3-sialyltransferase activity | Mus musculus | Alternative splicing Disulfide bond Glycoprotein Glycosyltransferase Golgi apparatus Lipid metabolism Membrane Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix | MHTEAVGGAA | MHTEAVGGAARRPQKLRSQAAAPACRAMPSEFTSAKLRSDCSRTSLQWYTRTQHKMRRPSLLIKDICKCTLVAFGVWLLYILILNYTAEECDMKRMHYVDPDRIKRAQSYAQEVLQKECRPRYAKTAMALLFEDRYSINLEPFVQKVPTASEAELKYDPPFGFRKFSSKVQSLLDMLPEHDFPEHLRAKACKRCVVVGNGGILHGLELGHALNQFDVVIRLNSAPVEGYSEHVGNKTTIRMTYPEGAPLSDVEYYANDLFVTVLFKSVDFKWLQAMVKNESLPFWVRLFFWKQVAEKVPLQPKHFRILNPVIIKETAFDILQYSEPQSRFWGHDKNIPTIGVIAVVLATHLCDEVSLAGFGYDLSQPRTPLHYFDSQCMGAMHWQVMHNVTTETKFLLKLLKEGVVEDLSGGIH | lipid metabolic process protein glycosylation Golgi membrane lactosylceramide alpha-2,3-sialyltransferase activity Mus musculus Alternative splicing Disulfide bond Glycoprotein Glycosyltransferase Golgi apparatus Lipid metabolism Membrane Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix MHTEAVGGAA MHTEAVGGAARRPQKLRSQAAAPACRAMPSEFTSAKLRSDCSRTSLQWYTRTQHKMRRPSLLIKDICKCTLVAFGVWLLYILILNYTAEECDMKRMHYVDPDRIKRAQSYAQEVLQKECRPRYAKTAMALLFEDRYSINLEPFVQKVPTASEAELKYDPPFGFRKFSSKVQSLLDMLPEHDFPEHLRAKACKRCVVVGNGGILHGLELGHALNQFDVVIRLNSAPVEGYSEHVGNKTTIRMTYPEGAPLSDVEYYANDLFVTVLFKSVDFKWLQAMVKNESLPFWVRLFFWKQVAEKVPLQPKHFRILNPVIIKETAFDILQYSEPQSRFWGHDKNIPTIGVIAVVLATHLCDEVSLAGFGYDLSQPRTPLHYFDSQCMGAMHWQVMHNVTTETKFLLKLLKEGVVEDLSGGIH |
CAMKK-AMPK signaling cascade positive regulation of protein phosphorylation protein autophosphorylation protein phosphorylation | cytosol; neuron projection; nucleoplasm | ATP binding calcium ion binding calmodulin binding calmodulin-dependent protein kinase activity protein kinase activator activity protein kinase activity protein serine kinase activity protein serine/threonine kinase activity | Rattus norvegicus | Acetylation Alternative splicing ATP-binding Calmodulin-binding Cell projection Cytoplasm Direct protein sequencing Kinase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MSSCVSSQPT | MSSCVSSQPTSDRAAPQDELGSGGVSRESQKPCEALRGLSSLSIHLGMESFIVVTECEPGRGVDLSLARDQPLEADGQELPLDASEPESRSLLSGGKMSLQERSQGGPASSSSLDMNGRCICPSLSYSPASSPQSSPRMPRRPTVESHHVSITGLQDCVQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTLKPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWVTRHGAEPLPSEDENCTLVEVTEEEVENSVKHIPSLATVILVKTMIRKRSFGNPFEGSRREERSLSAPGNLLTKKPTREWEPLSEPKEARQRRQPPGPRASPCGGGGSALVKGGPCVESCGAPAPGSPPRTPPQQPEEAMEPE | CAMKK-AMPK signaling cascade positive regulation of protein phosphorylation protein autophosphorylation protein phosphorylation cytosol; neuron projection; nucleoplasm ATP binding calcium ion binding calmodulin binding calmodulin-dependent protein kinase activity protein kinase activator activity protein kinase activity protein serine kinase activity protein serine/threonine kinase activity Rattus norvegicus Acetylation Alternative splicing ATP-binding Calmodulin-binding Cell projection Cytoplasm Direct protein sequencing Kinase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase MSSCVSSQPT MSSCVSSQPTSDRAAPQDELGSGGVSRESQKPCEALRGLSSLSIHLGMESFIVVTECEPGRGVDLSLARDQPLEADGQELPLDASEPESRSLLSGGKMSLQERSQGGPASSSSLDMNGRCICPSLSYSPASSPQSSPRMPRRPTVESHHVSITGLQDCVQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTLKPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWVTRHGAEPLPSEDENCTLVEVTEEEVENSVKHIPSLATVILVKTMIRKRSFGNPFEGSRREERSLSAPGNLLTKKPTREWEPLSEPKEARQRRQPPGPRASPCGGGGSALVKGGPCVESCGAPAPGSPPRTPPQQPEEAMEPE |
arachidonic acid metabolic process fatty acid metabolic process icosanoid biosynthetic process kidney development lauric acid metabolic process linoleic acid metabolic process | apical plasma membrane; cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle | alkane 1-monooxygenase activity arachidonic acid epoxygenase activity arachidonic acid monooxygenase activity heme binding iron ion binding leukotriene-B4 20-monooxygenase activity long-chain fatty acid omega-hydroxylase activity monooxygenase activity | Mus musculus | Endoplasmic reticulum Fatty acid metabolism Heme Iron Lipid metabolism Membrane Metal-binding Microsome Monooxygenase NADP Oxidoreductase Phosphoprotein Reference proteome Transmembrane Transmembrane helix | MSVSALSPTR | MSVSALSPTRFADSLSGFLQVASVLGLLLLLVKAVQFYLHRQWLLKAFQQFPSPPFHWFFGHEKFKGDQELQEIVSCIENFPSAFPRWFWGSKAYLTVYDPDYMKVILGRSDPKANGAYRLLAPWIGYGLLLLNGQPWFQHRRMLTPAFHYDILKPYVKNMADSIRLMLDKWERLADQDSSIEIFQHISLMTLDTVMKCAFSHKGSVQVDGNYRTYLQAIGDLNNLFHSRVRNIFHQNDTIYKLSSNGRLAKQACQLAHDHTDGVIKLRKDQLQDEGELEKIKKKRRLDFLDILLFARMENGDSMSDKDLRAEVDTFMFEGHDTTASGVSWIFYALATHPDHQQRCREEVQSLLGDGSSITWDHLDQIPYTTMCIKEALRLYPPVPGIVRELSTSVTFPDGRSLPKGVQVTLSIYGLHHNPKVWPNPEVFDPSRFAPDSPRHSHSFLPFSGGARNCIGKQFAMSELKVIVALTLLRFELLPDPTRVPMPLARLVLKSKNGIYLHLKKLH | arachidonic acid metabolic process fatty acid metabolic process icosanoid biosynthetic process kidney development lauric acid metabolic process linoleic acid metabolic process apical plasma membrane; cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle alkane 1-monooxygenase activity arachidonic acid epoxygenase activity arachidonic acid monooxygenase activity heme binding iron ion binding leukotriene-B4 20-monooxygenase activity long-chain fatty acid omega-hydroxylase activity monooxygenase activity Mus musculus Endoplasmic reticulum Fatty acid metabolism Heme Iron Lipid metabolism Membrane Metal-binding Microsome Monooxygenase NADP Oxidoreductase Phosphoprotein Reference proteome Transmembrane Transmembrane helix MSVSALSPTR MSVSALSPTRFADSLSGFLQVASVLGLLLLLVKAVQFYLHRQWLLKAFQQFPSPPFHWFFGHEKFKGDQELQEIVSCIENFPSAFPRWFWGSKAYLTVYDPDYMKVILGRSDPKANGAYRLLAPWIGYGLLLLNGQPWFQHRRMLTPAFHYDILKPYVKNMADSIRLMLDKWERLADQDSSIEIFQHISLMTLDTVMKCAFSHKGSVQVDGNYRTYLQAIGDLNNLFHSRVRNIFHQNDTIYKLSSNGRLAKQACQLAHDHTDGVIKLRKDQLQDEGELEKIKKKRRLDFLDILLFARMENGDSMSDKDLRAEVDTFMFEGHDTTASGVSWIFYALATHPDHQQRCREEVQSLLGDGSSITWDHLDQIPYTTMCIKEALRLYPPVPGIVRELSTSVTFPDGRSLPKGVQVTLSIYGLHHNPKVWPNPEVFDPSRFAPDSPRHSHSFLPFSGGARNCIGKQFAMSELKVIVALTLLRFELLPDPTRVPMPLARLVLKSKNGIYLHLKKLH |
intracellular signal transduction proteasome-mediated ubiquitin-dependent protein catabolic process protein ubiquitination ubiquitin-dependent protein catabolic process | cytosol; SCF ubiquitin ligase complex | ubiquitin ligase-substrate adaptor activity | Mus musculus | 3D-structure Alternative splicing Cytoplasm Reference proteome Ubl conjugation pathway | MGQTALARGS | MGQTALARGSSSTPTSQALYSDFSPPEGLEELLSAPPPDLVAQRHHGWNPKDCSENIDVKEGGLCFERRPVAQSTDGVRGKRGYSRGLHAWEISWPLEQRGTHAVVGVATALAPLQADHYAALLGSNSESWGWDIGRGKLYHQSKGLEAPQYPAGPQGEQLVVPERLLVVLDMEEGTLGYSIGGTYLGPAFRGLKGRTLYPSVSAVWGQCQVRIRYMGERRVEEPQSLLHLSRLCVRHALGDTRLGQISTLPLPPAMKRYLLYK | intracellular signal transduction proteasome-mediated ubiquitin-dependent protein catabolic process protein ubiquitination ubiquitin-dependent protein catabolic process cytosol; SCF ubiquitin ligase complex ubiquitin ligase-substrate adaptor activity Mus musculus 3D-structure Alternative splicing Cytoplasm Reference proteome Ubl conjugation pathway MGQTALARGS MGQTALARGSSSTPTSQALYSDFSPPEGLEELLSAPPPDLVAQRHHGWNPKDCSENIDVKEGGLCFERRPVAQSTDGVRGKRGYSRGLHAWEISWPLEQRGTHAVVGVATALAPLQADHYAALLGSNSESWGWDIGRGKLYHQSKGLEAPQYPAGPQGEQLVVPERLLVVLDMEEGTLGYSIGGTYLGPAFRGLKGRTLYPSVSAVWGQCQVRIRYMGERRVEEPQSLLHLSRLCVRHALGDTRLGQISTLPLPPAMKRYLLYK |
angiogenesis cardiac epithelial to mesenchymal transition cell adhesion cellular response to phorbol 13-acetate 12-myristate collagen catabolic process immune response to tumor cell innate immune response integrin-mediated signaling pathway male gonad development negative regulation of cell growth negative regulation of cell migration negative regulation of cell-matrix adhesion proteolysis response to hypobaric hypoxia tissue regeneration | acrosomal vesicle; adherens junction; cell surface; extracellular exosome; extracellular space; membrane; motile cilium | integrin binding metal ion binding metalloendopeptidase activity metallopeptidase activity SH3 domain binding | Mus musculus | Alternative splicing Angiogenesis Cell adhesion Cell junction Cell projection Cilium Cleavage on pair of basic residues Collagen degradation Cytoplasmic vesicle Disulfide bond EGF-like domain Flagellum Glycoprotein Hydrolase Membrane Metal-binding Metalloprotease Phosphoprotein Protease Reference proteome SH3-binding Signal Transmembrane Transmembrane helix Zinc Zymogen | MRLALLWALG | MRLALLWALGLLGAGSPRPSPPLPNIGGTEEEQQASPERTLSGSMESRVVQDSPPMSLADVLQTGLPEALRISLELDSESHVLELLQNRDLIPGRPTLVWYQPDGTRMVSEGYSLENCCYRGRVQGHPSSWVSLCACSGIRGLIVLSPERGYTLELGPGDLQRPVISRIQDHLLLGHTCAPSWHASVPTRAGPDLLLEQHHAHRLKRDVVTETKIVELVIVADNSEVRKYPDFQQLLNRTLEAALLLDTFFQPLNVRVALVGLEAWTQHNLIEMSSNPAVLLDNFLRWRRTDLLPRLPHDSAQLVTVTSFSGPMVGMAIQNSICSPDFSGGVNMDHSTSILGVASSIAHELGHSLGLDHDSPGHSCPCPGPAPAKSCIMEASTDFLPGLNFSNCSRQALEKALLEGMGSCLFERQPSLAPMSSLCGNMFVDPGEQCDCGFPDECTDPCCDHFTCQLRPGAQCASDGPCCQNCKLHPAGWLCRPPTDDCDLPEFCPGDSSQCPSDIRLGDGEPCASGEAVCMHGRCASYARQCQSLWGPGAQPAAPLCLQTANTRGNAFGSCGRSPGGSYMPCAPRDVMCGQLQCQWGRSQPLLGSVQDRLSEVLEANGTQLNCSWVDLDLGNDVAQPLLALPGTACGPGLVCIGHRCQPVDLLGAQECRRKCHGHGVCDSSGHCRCEEGWAPPDCMTQLKATSSLTTGLLLSLLLLLVLVLLGASYWHRARLHQRLCQLKGSSCQYRAPQSCPPERPGPPQRAQQMTGTKQASVVSFPVPPSRPLPPNPVPKKLQAALADRSNPPTRPLPADPVVRRPKSQGPTKPPPPRKPLPANPQGQHPPGDLPGPGDGSLPLVVPSRPAPPPPAASSLYL | angiogenesis cardiac epithelial to mesenchymal transition cell adhesion cellular response to phorbol 13-acetate 12-myristate collagen catabolic process immune response to tumor cell innate immune response integrin-mediated signaling pathway male gonad development negative regulation of cell growth negative regulation of cell migration negative regulation of cell-matrix adhesion proteolysis response to hypobaric hypoxia tissue regeneration acrosomal vesicle; adherens junction; cell surface; extracellular exosome; extracellular space; membrane; motile cilium integrin binding metal ion binding metalloendopeptidase activity metallopeptidase activity SH3 domain binding Mus musculus Alternative splicing Angiogenesis Cell adhesion Cell junction Cell projection Cilium Cleavage on pair of basic residues Collagen degradation Cytoplasmic vesicle Disulfide bond EGF-like domain Flagellum Glycoprotein Hydrolase Membrane Metal-binding Metalloprotease Phosphoprotein Protease Reference proteome SH3-binding Signal Transmembrane Transmembrane helix Zinc Zymogen MRLALLWALG MRLALLWALGLLGAGSPRPSPPLPNIGGTEEEQQASPERTLSGSMESRVVQDSPPMSLADVLQTGLPEALRISLELDSESHVLELLQNRDLIPGRPTLVWYQPDGTRMVSEGYSLENCCYRGRVQGHPSSWVSLCACSGIRGLIVLSPERGYTLELGPGDLQRPVISRIQDHLLLGHTCAPSWHASVPTRAGPDLLLEQHHAHRLKRDVVTETKIVELVIVADNSEVRKYPDFQQLLNRTLEAALLLDTFFQPLNVRVALVGLEAWTQHNLIEMSSNPAVLLDNFLRWRRTDLLPRLPHDSAQLVTVTSFSGPMVGMAIQNSICSPDFSGGVNMDHSTSILGVASSIAHELGHSLGLDHDSPGHSCPCPGPAPAKSCIMEASTDFLPGLNFSNCSRQALEKALLEGMGSCLFERQPSLAPMSSLCGNMFVDPGEQCDCGFPDECTDPCCDHFTCQLRPGAQCASDGPCCQNCKLHPAGWLCRPPTDDCDLPEFCPGDSSQCPSDIRLGDGEPCASGEAVCMHGRCASYARQCQSLWGPGAQPAAPLCLQTANTRGNAFGSCGRSPGGSYMPCAPRDVMCGQLQCQWGRSQPLLGSVQDRLSEVLEANGTQLNCSWVDLDLGNDVAQPLLALPGTACGPGLVCIGHRCQPVDLLGAQECRRKCHGHGVCDSSGHCRCEEGWAPPDCMTQLKATSSLTTGLLLSLLLLLVLVLLGASYWHRARLHQRLCQLKGSSCQYRAPQSCPPERPGPPQRAQQMTGTKQASVVSFPVPPSRPLPPNPVPKKLQAALADRSNPPTRPLPADPVVRRPKSQGPTKPPPPRKPLPANPQGQHPPGDLPGPGDGSLPLVVPSRPAPPPPAASSLYL |
2-oxoglutarate metabolic process female gonad development glutathione metabolic process glyoxylate cycle isocitrate metabolic process NADP metabolic process regulation of phospholipid biosynthetic process regulation of phospholipid catabolic process response to organic cyclic compound response to oxidative stress response to steroid hormone tricarboxylic acid cycle | cytoplasm; cytosol; mitochondrion; peroxisome | identical protein binding isocitrate dehydrogenase (NADP+) activity magnesium ion binding NAD binding NADP binding protein homodimerization activity | Mus musculus | 3D-structure Acetylation Cytoplasm Direct protein sequencing Glyoxylate bypass Magnesium Manganese Metal-binding NADP Oxidoreductase Phosphoprotein Reference proteome Tricarboxylic acid cycle | MSRKIQGGSV | MSRKIQGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGTQKVTYMVHDFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFEAQKICYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFAKALEDVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAKL | 2-oxoglutarate metabolic process female gonad development glutathione metabolic process glyoxylate cycle isocitrate metabolic process NADP metabolic process regulation of phospholipid biosynthetic process regulation of phospholipid catabolic process response to organic cyclic compound response to oxidative stress response to steroid hormone tricarboxylic acid cycle cytoplasm; cytosol; mitochondrion; peroxisome identical protein binding isocitrate dehydrogenase (NADP+) activity magnesium ion binding NAD binding NADP binding protein homodimerization activity Mus musculus 3D-structure Acetylation Cytoplasm Direct protein sequencing Glyoxylate bypass Magnesium Manganese Metal-binding NADP Oxidoreductase Phosphoprotein Reference proteome Tricarboxylic acid cycle MSRKIQGGSV MSRKIQGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGTQKVTYMVHDFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFEAQKICYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFAKALEDVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAKL |
protein localization | cytosol; mitochondrion; plasma membrane; protein-containing complex | protein kinase A binding | Mus musculus | Alternative splicing Cytoplasm Membrane Mitochondrion Phosphoprotein Reference proteome Repeat Transit peptide | MRGAGPSPRH | MRGAGPSPRHSPRALRPDPGPAMSFFRRKVKGKEQEKTLDVKSTKASVAVHSPQKSTKNHALLEAAGPSHVAINAISANMDSFSSSRTATLKKQPSHMEAAHFGDLGRSCLDYQTQETKSSLSKTLEQVLRDTVVLPYFLQFMELRRMEHLVKFWLEAESFHSTTWSRIRAHSLNTVKQSSLAEPVSPSKRHETPASSVTEALDRRLGDSSSAPLLVTQSEGTDLSSRTQNPQNHLLLSQEGHSARSLHREVARTGSHQIPTDSQDSSSRLAVGSRNSCSSPLRELSEKLMKSIEQDAVNTFTKYISPDAAKPIPITEAMRNDIIAKICGEDGQVDPNCFVLAQAVVFSAMEQEHFSEFLRSHHFCKYQIEVLTSGTVYLADILFCESALFYFSEYMEKEDAVNILQFWLAADNFQSQLAAKKGQYDGQEAQNDAMILYDKYFSLQATHPLGFDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSNLYYKYLNDLIHSVRGDEFLGGNVSLAAHGSVCLPEESHSGGSDGSTAQSSVKKASIKILKNFDEAIIVDAASLDPESLYQRTYAGKMSFGRVSDLGQFIRESEPEPDVKKSKGFMFSQAMKKWVQGNTDEAQEELAWKIAKMIVSDVMQQAHHDQPLEKSTKL | protein localization cytosol; mitochondrion; plasma membrane; protein-containing complex protein kinase A binding Mus musculus Alternative splicing Cytoplasm Membrane Mitochondrion Phosphoprotein Reference proteome Repeat Transit peptide MRGAGPSPRH MRGAGPSPRHSPRALRPDPGPAMSFFRRKVKGKEQEKTLDVKSTKASVAVHSPQKSTKNHALLEAAGPSHVAINAISANMDSFSSSRTATLKKQPSHMEAAHFGDLGRSCLDYQTQETKSSLSKTLEQVLRDTVVLPYFLQFMELRRMEHLVKFWLEAESFHSTTWSRIRAHSLNTVKQSSLAEPVSPSKRHETPASSVTEALDRRLGDSSSAPLLVTQSEGTDLSSRTQNPQNHLLLSQEGHSARSLHREVARTGSHQIPTDSQDSSSRLAVGSRNSCSSPLRELSEKLMKSIEQDAVNTFTKYISPDAAKPIPITEAMRNDIIAKICGEDGQVDPNCFVLAQAVVFSAMEQEHFSEFLRSHHFCKYQIEVLTSGTVYLADILFCESALFYFSEYMEKEDAVNILQFWLAADNFQSQLAAKKGQYDGQEAQNDAMILYDKYFSLQATHPLGFDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSNLYYKYLNDLIHSVRGDEFLGGNVSLAAHGSVCLPEESHSGGSDGSTAQSSVKKASIKILKNFDEAIIVDAASLDPESLYQRTYAGKMSFGRVSDLGQFIRESEPEPDVKKSKGFMFSQAMKKWVQGNTDEAQEELAWKIAKMIVSDVMQQAHHDQPLEKSTKL |
cellular response to arsenic-containing substance cellular response to cytokine stimulus cellular response to gamma radiation cellular response to hydroxyurea cellular response to testosterone stimulus male gonad development negative regulation of protein localization to chromatin positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II proteasome-mediated ubiquitin-dependent protein catabolic process protein autoubiquitination protein K11-linked ubiquitination protein K48-linked ubiquitination protein K6-linked ubiquitination protein K63-linked ubiquitination protein ubiquitination regulation of kinetochore assembly regulation of spindle assembly response to arsenic-containing substance response to estradiol response to human chorionic gonadotropin spermatogenesis | cytoplasm; nucleoplasm; nucleus; PML body | DNA binding identical protein binding nuclear androgen receptor binding nuclear estrogen receptor binding nucleosome binding SUMO polymer binding TBP-class protein binding ubiquitin conjugating enzyme binding ubiquitin protein ligase activity ubiquitin-protein transferase activity zinc ion binding | Rattus norvegicus | 3D-structure Activator Cytoplasm DNA-binding Metal-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Transferase Ubl conjugation Ubl conjugation pathway Zinc Zinc-finger | MSTRNPQRKR | MSTRNPQRKRRGGAVNSRQTQKRTRETTSTPEISLEAEPIELVETVGDEIVDLTCESLEPVVVDLTHNDSVVIVEERRRPRRNGRRLRQDHADSCVVSSDDEELSKDKDVYVTTHTPRSTKDEGTTGLRPSGTVSCPICMDGYSEIVQNGRLIVSTECGHVFCSQCLRDSLKNANTCPTCRKKINHKRYHPIYI | cellular response to arsenic-containing substance cellular response to cytokine stimulus cellular response to gamma radiation cellular response to hydroxyurea cellular response to testosterone stimulus male gonad development negative regulation of protein localization to chromatin positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II proteasome-mediated ubiquitin-dependent protein catabolic process protein autoubiquitination protein K11-linked ubiquitination protein K48-linked ubiquitination protein K6-linked ubiquitination protein K63-linked ubiquitination protein ubiquitination regulation of kinetochore assembly regulation of spindle assembly response to arsenic-containing substance response to estradiol response to human chorionic gonadotropin spermatogenesis cytoplasm; nucleoplasm; nucleus; PML body DNA binding identical protein binding nuclear androgen receptor binding nuclear estrogen receptor binding nucleosome binding SUMO polymer binding TBP-class protein binding ubiquitin conjugating enzyme binding ubiquitin protein ligase activity ubiquitin-protein transferase activity zinc ion binding Rattus norvegicus 3D-structure Activator Cytoplasm DNA-binding Metal-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Transferase Ubl conjugation Ubl conjugation pathway Zinc Zinc-finger MSTRNPQRKR MSTRNPQRKRRGGAVNSRQTQKRTRETTSTPEISLEAEPIELVETVGDEIVDLTCESLEPVVVDLTHNDSVVIVEERRRPRRNGRRLRQDHADSCVVSSDDEELSKDKDVYVTTHTPRSTKDEGTTGLRPSGTVSCPICMDGYSEIVQNGRLIVSTECGHVFCSQCLRDSLKNANTCPTCRKKINHKRYHPIYI |
brain development cilium assembly fat cell differentiation intracellular protein transport protein localization to cilium protein localization to non-motile cilium protein polymerization protein targeting to membrane protein transport from ciliary membrane to plasma membrane Ras protein signal transduction regulation of smoothened signaling pathway retina layer formation vesicle-mediated transport Wnt signaling pathway | axonemal microtubule; axoneme; ciliary membrane; cilium; cytoplasm; cytosol; membrane; membrane coat; microtubule cytoskeleton | GTP binding GTPase activity metal ion binding NAD+-protein ADP-ribosyltransferase activity phospholipid binding | Mus musculus | Alternative splicing Cell membrane Cell projection Cilium biogenesis/degradation Cytoplasm Cytoskeleton GTP-binding Lipoprotein Magnesium Membrane Metal-binding Myristate Nucleotide-binding Protein transport Reference proteome Transport | MGLLDRLSGL | MGLLDRLSGLLGLKKKEVHVLCLGLDNSGKTTIINKLKPSNAQSQDIVPTIGFSIEKFKSSSLSFTVFDMSGQGRYRNLWEHYYKDGQAIIFVIDSSDKLRMVVAKEELDTLLNHPDIKHRRIPILFFANKMDLRDSVTSVKVSQLLCLESIKDKPWHICASDAIKGEGLQEGVDWLQDQIQAVKT | brain development cilium assembly fat cell differentiation intracellular protein transport protein localization to cilium protein localization to non-motile cilium protein polymerization protein targeting to membrane protein transport from ciliary membrane to plasma membrane Ras protein signal transduction regulation of smoothened signaling pathway retina layer formation vesicle-mediated transport Wnt signaling pathway axonemal microtubule; axoneme; ciliary membrane; cilium; cytoplasm; cytosol; membrane; membrane coat; microtubule cytoskeleton GTP binding GTPase activity metal ion binding NAD+-protein ADP-ribosyltransferase activity phospholipid binding Mus musculus Alternative splicing Cell membrane Cell projection Cilium biogenesis/degradation Cytoplasm Cytoskeleton GTP-binding Lipoprotein Magnesium Membrane Metal-binding Myristate Nucleotide-binding Protein transport Reference proteome Transport MGLLDRLSGL MGLLDRLSGLLGLKKKEVHVLCLGLDNSGKTTIINKLKPSNAQSQDIVPTIGFSIEKFKSSSLSFTVFDMSGQGRYRNLWEHYYKDGQAIIFVIDSSDKLRMVVAKEELDTLLNHPDIKHRRIPILFFANKMDLRDSVTSVKVSQLLCLESIKDKPWHICASDAIKGEGLQEGVDWLQDQIQAVKT |
fusion of sperm to egg plasma membrane involved in single fertilization peptidyl-tyrosine sulfation prevention of polyspermy | endoplasmic reticulum; Golgi apparatus; Golgi membrane | protein homodimerization activity protein-tyrosine sulfotransferase activity | Mus musculus | Disulfide bond Glycoprotein Golgi apparatus Membrane Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix | MRLSVRKVLL | MRLSVRKVLLAAGCALALVLAVQLGQQVLECRAVLGGTRNPRRMRPEQEELVMLGADHVEYRYGKAMPLIFVGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWTKSGREKLRLDEAGVTDEVLDAAMQAFILEVIAKHGEPARVLCNKDPFTLKSSVYLARLFPNSKFLLMVRDGRASVHSMITRKVTIAGFDLSSYRDCLTKWNKAIEVMYAQCMEVGRDKCLPVYYEQLVLHPRRSLKRILDFLGIAWSDTVLHHEDLIGKPGGVSLSKIERSTDQVIKPVNLEALSKWTGHIPRDVVRDMAQIAPMLARLGYDPYANPPNYGNPDPIVINNTHRVLKGDYKTPANLKGYFQVNQNSTSPHLGSS | fusion of sperm to egg plasma membrane involved in single fertilization peptidyl-tyrosine sulfation prevention of polyspermy endoplasmic reticulum; Golgi apparatus; Golgi membrane protein homodimerization activity protein-tyrosine sulfotransferase activity Mus musculus Disulfide bond Glycoprotein Golgi apparatus Membrane Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix MRLSVRKVLL MRLSVRKVLLAAGCALALVLAVQLGQQVLECRAVLGGTRNPRRMRPEQEELVMLGADHVEYRYGKAMPLIFVGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWTKSGREKLRLDEAGVTDEVLDAAMQAFILEVIAKHGEPARVLCNKDPFTLKSSVYLARLFPNSKFLLMVRDGRASVHSMITRKVTIAGFDLSSYRDCLTKWNKAIEVMYAQCMEVGRDKCLPVYYEQLVLHPRRSLKRILDFLGIAWSDTVLHHEDLIGKPGGVSLSKIERSTDQVIKPVNLEALSKWTGHIPRDVVRDMAQIAPMLARLGYDPYANPPNYGNPDPIVINNTHRVLKGDYKTPANLKGYFQVNQNSTSPHLGSS |
de novo' NAD biosynthetic process from tryptophan anthranilate metabolic process cellular response to interleukin-1 cellular response to lipopolysaccharide kynurenic acid biosynthetic process kynurenine metabolic process L-kynurenine metabolic process NAD metabolic process positive regulation of glutamate secretion positive regulation of glutamate secretion, neurotransmission quinolinate biosynthetic process response to lipopolysaccharide response to salt stress tryptophan catabolic process | extracellular space; mitochondrial outer membrane | FAD binding flavin adenine dinucleotide binding kynurenine 3-monooxygenase activity NAD(P)H oxidase H2O2-forming activity | Rattus norvegicus | 3D-structure FAD Flavoprotein Membrane Mitochondrion Mitochondrion outer membrane Monooxygenase NADP Oxidoreductase Pyridine nucleotide biosynthesis Reference proteome Transmembrane Transmembrane helix | MASSDTEGKR | MASSDTEGKRVVVIGGGLVGALNACFLAKRNFQVDVYEAREDIRVANFMRGRSINLALSYRGRQALKAVGLEDQIVSKGVPMKARMIHSLSGKKSAIPYGNKSQYILSISREKLNKDLLTAVESYPNAKVHFGHKLSKCCPEEGILTMLGPNKVPRDITCDLIVGCDGAYSTVRAHLMKKPRFDYSQQYIPHGYMELTIPPKNGEYAMEPNCLHIWPRNAFMMIALPNMDKSFTCTLFMSFEEFEKLPTHSDVLDFFQKNFPDAIPLMGEQALMRDFFLLPAQPMISVKCSPFHLKSRCVLMGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFNNDLSVCLPEFSRFRIPDDHAISDLSMYNYIEMRAHVNSRWFLFQRLLDKFLHALMPSTFIPLYTMVAFTRIRYHEAVLRWHWQKKVINRGLFVLGSLVAIGSAYILVHHLSPRPLELLRSAWTGTSGHWNRSADISPRVPWSH | de novo' NAD biosynthetic process from tryptophan anthranilate metabolic process cellular response to interleukin-1 cellular response to lipopolysaccharide kynurenic acid biosynthetic process kynurenine metabolic process L-kynurenine metabolic process NAD metabolic process positive regulation of glutamate secretion positive regulation of glutamate secretion, neurotransmission quinolinate biosynthetic process response to lipopolysaccharide response to salt stress tryptophan catabolic process extracellular space; mitochondrial outer membrane FAD binding flavin adenine dinucleotide binding kynurenine 3-monooxygenase activity NAD(P)H oxidase H2O2-forming activity Rattus norvegicus 3D-structure FAD Flavoprotein Membrane Mitochondrion Mitochondrion outer membrane Monooxygenase NADP Oxidoreductase Pyridine nucleotide biosynthesis Reference proteome Transmembrane Transmembrane helix MASSDTEGKR MASSDTEGKRVVVIGGGLVGALNACFLAKRNFQVDVYEAREDIRVANFMRGRSINLALSYRGRQALKAVGLEDQIVSKGVPMKARMIHSLSGKKSAIPYGNKSQYILSISREKLNKDLLTAVESYPNAKVHFGHKLSKCCPEEGILTMLGPNKVPRDITCDLIVGCDGAYSTVRAHLMKKPRFDYSQQYIPHGYMELTIPPKNGEYAMEPNCLHIWPRNAFMMIALPNMDKSFTCTLFMSFEEFEKLPTHSDVLDFFQKNFPDAIPLMGEQALMRDFFLLPAQPMISVKCSPFHLKSRCVLMGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFNNDLSVCLPEFSRFRIPDDHAISDLSMYNYIEMRAHVNSRWFLFQRLLDKFLHALMPSTFIPLYTMVAFTRIRYHEAVLRWHWQKKVINRGLFVLGSLVAIGSAYILVHHLSPRPLELLRSAWTGTSGHWNRSADISPRVPWSH |
endosomal transport intracellular transport protein targeting signal transduction | cytosol; endosome; recycling endosome; trans-Golgi network transport vesicle membrane | enzyme binding protein domain specific binding | Rattus norvegicus | Coiled coil Endosome Reference proteome | MAPFGRNLLK | MAPFGRNLLKTRHKNRSPTKDMDPEEKEIVVWVCQEEKIVCGLTKRTTSIDVIQALLEEHEATFGEKRFLLGKASDYCIVEKWRGSERALPPLTRILKLWKAWGDEQPNMQFVLVKTDAFLPVPLWRTAETKLVQNNEKPWELSPANYMKTLPPDKQKRIVRKTFRKLAKIRQDTGSHDRDNMECLVHLIISQDHTIHQQVQRMKELDMEIEKCEAKIHLDRIGNDGADYVQEAYLMPRSSEEEQKLDFQSEDNQTLEDLNDGEGVSQLEEQLQYYRALIDKLSAEIEREVKGAGTDGSEDMEGAAACELENSDLESVKCDLEKSMKAGLKIHSHLSGIQREIKYSDSLLQMKAREYELLAKEFSSLHISSKDGCQGKENRGKEAEASSSNGEIPPLTQRVFNTYTNDTDSDTGISSNHSQDSETTLGDVLLLAT | endosomal transport intracellular transport protein targeting signal transduction cytosol; endosome; recycling endosome; trans-Golgi network transport vesicle membrane enzyme binding protein domain specific binding Rattus norvegicus Coiled coil Endosome Reference proteome MAPFGRNLLK MAPFGRNLLKTRHKNRSPTKDMDPEEKEIVVWVCQEEKIVCGLTKRTTSIDVIQALLEEHEATFGEKRFLLGKASDYCIVEKWRGSERALPPLTRILKLWKAWGDEQPNMQFVLVKTDAFLPVPLWRTAETKLVQNNEKPWELSPANYMKTLPPDKQKRIVRKTFRKLAKIRQDTGSHDRDNMECLVHLIISQDHTIHQQVQRMKELDMEIEKCEAKIHLDRIGNDGADYVQEAYLMPRSSEEEQKLDFQSEDNQTLEDLNDGEGVSQLEEQLQYYRALIDKLSAEIEREVKGAGTDGSEDMEGAAACELENSDLESVKCDLEKSMKAGLKIHSHLSGIQREIKYSDSLLQMKAREYELLAKEFSSLHISSKDGCQGKENRGKEAEASSSNGEIPPLTQRVFNTYTNDTDSDTGISSNHSQDSETTLGDVLLLAT |
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway gamma-aminobutyric acid signaling pathway neuron-glial cell signaling synaptic transmission, GABAergic | cytoplasm; dendrite; G protein-coupled GABA receptor complex; G protein-coupled receptor heterodimeric complex; GABA receptor complex; GABA-ergic synapse; glutamatergic synapse; neuron projection; perikaryon; plasma membrane; postsynaptic membrane; presynaptic membrane | G protein-coupled GABA receptor activity protein heterodimerization activity | Rattus norvegicus | Cell membrane Cell projection Coiled coil Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transducer Transmembrane Transmembrane helix | MASPPSSGQP | MASPPSSGQPRPPPPPPPPARLLLPLLLSLLLWLAPGAWGWTRGAPRPPPSSPPLSIMGLMPLTKEVAKGSIGRGVLPAVELAIEQIRNESLLRPYFLDLRLYDTECDNAKGLKAFYDAIKYGPNHLMVFGGVCPSVTSIIAESLQGWNLVQLSFAATTPVLADKKKYPYFFRTVPSDNAVNPAILKLLKHFRWRRVGTLTQDVQRFSEVRNDLTGVLYGEDIEISDTESFSNDPCTSVKKLKGNDVRIILGQFDQNMAAKVFCCAFEESMFGSKYQWIIPGWYEPAWWEQVHVEANSSRCLRRSLLAAMEGYIGVDFEPLSSKQIKTISGKTPQQFEREYNSKRSGVGPSKFHGYAYDGIWVIAKTLQRAMETLHASSRHQRIQDFNYTDHTLGKIILNAMNETNFFGVTGQVVFRNGERMGTIKFTQFQDSREVKVGEYNAVADTLEIINDTIRFQGSEPPKDKTIILEQLRKISLPLYSILSALTILGMIMASAFLFFNIKNRNQKLIKMSSPYMNNLIILGGMLSYASIFLFGLDGSFVSEKTFETLCTVRTWILTVGYTTAFGAMFAKTWRVHAIFKNVKMKKKIIKDQKLLVIVGGMLLIDLCILICWQAVDPLRRTVERYSMEPDPAGRDISIRPLLEHCENTHMTIWLGIVYAYKGLLMLFGCFLAWETRNVSIPALNDSKYIGMSVYNVGIMCIIGAAVSFLTRDQPNVQFCIVALVIIFCSTITLCLVFVPKLITLRTNPDAATQNRRFQFTQNQKKEDSKTSTSVTSVNQASTSRLEGLQSENHRLRMKITELDKDLEEVTMQLQDTPEKTTYIKQNHYQELNDILSLGNFTESTDGGKAILKNHLDQNPQLQWNTTEPSRTCKDPIEDINSPEHIQRRLSLQLPILHHAYLPSIGGVDASCVSPCVSPTASPRHRHVPPSFRVMVSGL | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway gamma-aminobutyric acid signaling pathway neuron-glial cell signaling synaptic transmission, GABAergic cytoplasm; dendrite; G protein-coupled GABA receptor complex; G protein-coupled receptor heterodimeric complex; GABA receptor complex; GABA-ergic synapse; glutamatergic synapse; neuron projection; perikaryon; plasma membrane; postsynaptic membrane; presynaptic membrane G protein-coupled GABA receptor activity protein heterodimerization activity Rattus norvegicus Cell membrane Cell projection Coiled coil Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transducer Transmembrane Transmembrane helix MASPPSSGQP MASPPSSGQPRPPPPPPPPARLLLPLLLSLLLWLAPGAWGWTRGAPRPPPSSPPLSIMGLMPLTKEVAKGSIGRGVLPAVELAIEQIRNESLLRPYFLDLRLYDTECDNAKGLKAFYDAIKYGPNHLMVFGGVCPSVTSIIAESLQGWNLVQLSFAATTPVLADKKKYPYFFRTVPSDNAVNPAILKLLKHFRWRRVGTLTQDVQRFSEVRNDLTGVLYGEDIEISDTESFSNDPCTSVKKLKGNDVRIILGQFDQNMAAKVFCCAFEESMFGSKYQWIIPGWYEPAWWEQVHVEANSSRCLRRSLLAAMEGYIGVDFEPLSSKQIKTISGKTPQQFEREYNSKRSGVGPSKFHGYAYDGIWVIAKTLQRAMETLHASSRHQRIQDFNYTDHTLGKIILNAMNETNFFGVTGQVVFRNGERMGTIKFTQFQDSREVKVGEYNAVADTLEIINDTIRFQGSEPPKDKTIILEQLRKISLPLYSILSALTILGMIMASAFLFFNIKNRNQKLIKMSSPYMNNLIILGGMLSYASIFLFGLDGSFVSEKTFETLCTVRTWILTVGYTTAFGAMFAKTWRVHAIFKNVKMKKKIIKDQKLLVIVGGMLLIDLCILICWQAVDPLRRTVERYSMEPDPAGRDISIRPLLEHCENTHMTIWLGIVYAYKGLLMLFGCFLAWETRNVSIPALNDSKYIGMSVYNVGIMCIIGAAVSFLTRDQPNVQFCIVALVIIFCSTITLCLVFVPKLITLRTNPDAATQNRRFQFTQNQKKEDSKTSTSVTSVNQASTSRLEGLQSENHRLRMKITELDKDLEEVTMQLQDTPEKTTYIKQNHYQELNDILSLGNFTESTDGGKAILKNHLDQNPQLQWNTTEPSRTCKDPIEDINSPEHIQRRLSLQLPILHHAYLPSIGGVDASCVSPCVSPTASPRHRHVPPSFRVMVSGL |
positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II | cytoplasm; nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific identical protein binding metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA binding | Rattus norvegicus | Alternative splicing Coiled coil Cytoplasm Direct protein sequencing DNA-binding Isopeptide bond Metal-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Ubl conjugation Zinc | MATPDVSVHM | MATPDVSVHMEEVVVVTTPDTAVDGSGVEEVKTVLVTTNLAPHGGDLTEDNMETENAAAAACAFTASSQLKEAVLVKMAEEGENLEAEIVYPITCGDSRANLIWRKFVCPGINVKCVQYDEHVISPKEFVHLAGKSTLKDWKRAIRMNGIMLRKIMDSGELDFYQHDKVCSNTCRSTKIDLSGARVSLSSPTSTEYIPLTPAAADVNGSPATITIETCEDPGDWTTTIGDDTFAFWRGLKDAGLLDEVIQEFQQELEETMKGLQQRVQDPPLQLRDAVLLNNIVQNFGMLDLVKKVLASHKCQMDRSREQYARDLAALEQQCDEHRRRAKELKHKSQHLSNVLMTLTPVSLPSPMKRPRLARATSGPAAMASQVLTQSAQIALGPGMPMSQLTSVPLGKVVSTLPSTVLGKGSPQAAPASSPASPLLGGYTVLASSGSTFPSTVEIHPDTSSLTVLSTAAMQDGTTVLKVVSPLQLLTLPGLGPTLQNVAQASPAGSTIVTMPTAAATGPEEHTATIEVAAVAEDHEQK | positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II cytoplasm; nucleus DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific identical protein binding metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA binding Rattus norvegicus Alternative splicing Coiled coil Cytoplasm Direct protein sequencing DNA-binding Isopeptide bond Metal-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Ubl conjugation Zinc MATPDVSVHM MATPDVSVHMEEVVVVTTPDTAVDGSGVEEVKTVLVTTNLAPHGGDLTEDNMETENAAAAACAFTASSQLKEAVLVKMAEEGENLEAEIVYPITCGDSRANLIWRKFVCPGINVKCVQYDEHVISPKEFVHLAGKSTLKDWKRAIRMNGIMLRKIMDSGELDFYQHDKVCSNTCRSTKIDLSGARVSLSSPTSTEYIPLTPAAADVNGSPATITIETCEDPGDWTTTIGDDTFAFWRGLKDAGLLDEVIQEFQQELEETMKGLQQRVQDPPLQLRDAVLLNNIVQNFGMLDLVKKVLASHKCQMDRSREQYARDLAALEQQCDEHRRRAKELKHKSQHLSNVLMTLTPVSLPSPMKRPRLARATSGPAAMASQVLTQSAQIALGPGMPMSQLTSVPLGKVVSTLPSTVLGKGSPQAAPASSPASPLLGGYTVLASSGSTFPSTVEIHPDTSSLTVLSTAAMQDGTTVLKVVSPLQLLTLPGLGPTLQNVAQASPAGSTIVTMPTAAATGPEEHTATIEVAAVAEDHEQK |
cell cycle cell division DNA damage response in utero embryonic development negative regulation by host of viral genome replication negative regulation of stem cell differentiation positive regulation of DNA-templated transcription, elongation positive regulation of transcription elongation by RNA polymerase II regulation of signal transduction regulation of transcription by RNA polymerase II transcription by RNA polymerase II | cyclin K-CDK12 complex; cyclin K-CDK13 complex; cyclin/CDK positive transcription elongation factor complex; nucleoplasm; nucleus | cyclin-dependent protein serine/threonine kinase activator activity cyclin-dependent protein serine/threonine kinase activity protein kinase binding RNA polymerase II CTD heptapeptide repeat kinase activity | Mus musculus | Cell cycle Cell division Cyclin Mitosis Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MKENKENSSP | MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTARSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQGPQSQPSQGSEAAQPPQKDSQQSAQQQQQQAQQPKKPSPQPSPPRQAKRAVVVSPKEENKATEPPPPPKIPKLEATHPPLPPAHPPPDRKPPLAPALGEAEATGPVETSDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPASFPPPTIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPPGMPPVGGLGRAAWMR | cell cycle cell division DNA damage response in utero embryonic development negative regulation by host of viral genome replication negative regulation of stem cell differentiation positive regulation of DNA-templated transcription, elongation positive regulation of transcription elongation by RNA polymerase II regulation of signal transduction regulation of transcription by RNA polymerase II transcription by RNA polymerase II cyclin K-CDK12 complex; cyclin K-CDK13 complex; cyclin/CDK positive transcription elongation factor complex; nucleoplasm; nucleus cyclin-dependent protein serine/threonine kinase activator activity cyclin-dependent protein serine/threonine kinase activity protein kinase binding RNA polymerase II CTD heptapeptide repeat kinase activity Mus musculus Cell cycle Cell division Cyclin Mitosis Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation MKENKENSSP MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTARSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQGPQSQPSQGSEAAQPPQKDSQQSAQQQQQQAQQPKKPSPQPSPPRQAKRAVVVSPKEENKATEPPPPPKIPKLEATHPPLPPAHPPPDRKPPLAPALGEAEATGPVETSDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPASFPPPTIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPPGMPPVGGLGRAAWMR |
adaptive immune response defense response to Gram-negative bacterium innate immune response mucosal immune response negative regulation of adaptive immune memory response negative regulation of angiogenesis negative regulation of CD4-positive, alpha-beta T cell costimulation negative regulation of T cell receptor signaling pathway phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of endothelial cell apoptotic process positive regulation of natural killer cell cytokine production positive regulation of natural killer cell degranulation positive regulation of natural killer cell mediated cytotoxicity positive regulation of natural killer cell mediated immune response to tumor cell positive regulation of type II interferon production T cell costimulation | extracellular region; plasma membrane; side of membrane | activating MHC class I receptor activity kinase binding MHC class I protein complex binding MHC class I receptor activity MHC class Ib receptor activity signaling receptor binding | Mus musculus | Adaptive immunity Cell membrane Disulfide bond Glycoprotein GPI-anchor Immunity Immunoglobulin domain Innate immunity Lipoprotein Membrane Receptor Reference proteome Secreted Signal | MQRILMAPGQ | MQRILMAPGQSCCALAILLAIVNFQHGGCIHVTSSASQKGGRLDLTCTLWHKKDEAEGLILFWCKDNPWNCSPETNLEQLRVKRDPETDGITEKSSQLVFTIEQATPSDSGTYQCCARSQKPEIYIHGHFLSVLVTGNHTEIRQRQRSHPDFSHINGTLSSGFLQVKAWGMLVTSLVALQALYTL | adaptive immune response defense response to Gram-negative bacterium innate immune response mucosal immune response negative regulation of adaptive immune memory response negative regulation of angiogenesis negative regulation of CD4-positive, alpha-beta T cell costimulation negative regulation of T cell receptor signaling pathway phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of endothelial cell apoptotic process positive regulation of natural killer cell cytokine production positive regulation of natural killer cell degranulation positive regulation of natural killer cell mediated cytotoxicity positive regulation of natural killer cell mediated immune response to tumor cell positive regulation of type II interferon production T cell costimulation extracellular region; plasma membrane; side of membrane activating MHC class I receptor activity kinase binding MHC class I protein complex binding MHC class I receptor activity MHC class Ib receptor activity signaling receptor binding Mus musculus Adaptive immunity Cell membrane Disulfide bond Glycoprotein GPI-anchor Immunity Immunoglobulin domain Innate immunity Lipoprotein Membrane Receptor Reference proteome Secreted Signal MQRILMAPGQ MQRILMAPGQSCCALAILLAIVNFQHGGCIHVTSSASQKGGRLDLTCTLWHKKDEAEGLILFWCKDNPWNCSPETNLEQLRVKRDPETDGITEKSSQLVFTIEQATPSDSGTYQCCARSQKPEIYIHGHFLSVLVTGNHTEIRQRQRSHPDFSHINGTLSSGFLQVKAWGMLVTSLVALQALYTL |
bone morphogenesis cardiac septum morphogenesis negative regulation of retinoic acid receptor signaling pathway outflow tract morphogenesis regulation of ossification regulation of retinoic acid receptor signaling pathway retinoid metabolic process roof of mouth development | lipid droplet; membrane | NAD-retinol dehydrogenase activity NADP-retinol dehydrogenase activity | Mus musculus | Alternative splicing Lipid metabolism Membrane NADP Oxidoreductase Reference proteome Transmembrane Transmembrane helix | MVWKWLGALV | MVWKWLGALVVFPLQMIYLVTKAAVGMVLPPKLRDLSRESVLITGGGRGIGRHLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQMAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHVNTLGQFWTTKAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTVLPFHTSTEMFQGMRVRFPNLFPPLKPETVARRTVDAVQQNQALLLLPWTMNILIILKSILPQAALEEIHRFSGTYTCMNTFKGRT | bone morphogenesis cardiac septum morphogenesis negative regulation of retinoic acid receptor signaling pathway outflow tract morphogenesis regulation of ossification regulation of retinoic acid receptor signaling pathway retinoid metabolic process roof of mouth development lipid droplet; membrane NAD-retinol dehydrogenase activity NADP-retinol dehydrogenase activity Mus musculus Alternative splicing Lipid metabolism Membrane NADP Oxidoreductase Reference proteome Transmembrane Transmembrane helix MVWKWLGALV MVWKWLGALVVFPLQMIYLVTKAAVGMVLPPKLRDLSRESVLITGGGRGIGRHLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQMAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHVNTLGQFWTTKAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTVLPFHTSTEMFQGMRVRFPNLFPPLKPETVARRTVDAVQQNQALLLLPWTMNILIILKSILPQAALEEIHRFSGTYTCMNTFKGRT |
face development fibroblast migration in utero embryonic development platelet-derived growth factor receptor signaling pathway respiratory system process skeletal system morphogenesis smooth muscle tissue development vasculature development | cytoplasm | DNA binding zinc ion binding | Mus musculus | 3D-structure Acetylation Cytoplasm Metal-binding Phosphoprotein Reference proteome Ubl conjugation pathway Zinc Zinc-finger | MAQETNQTPG | MAQETNQTPGPMLCSTGCGFYGNPRTNGMCSVCYKEHLQRQQNSGRMSPMGTASGSNSPTSDSASVQRADAGLNNCEGAAGSTSEKSRNVPVAALPVTQQMTEMSISREDKITTPKTEVSEPVVTQPSPSVSQPSSSQSEEKAPELPKPKKNRCFMCRKKVGLTGFDCRCGNLFCGLHRYSDKHNCPYDYKAEAAAKIRKENPVVVAEKIQRI | face development fibroblast migration in utero embryonic development platelet-derived growth factor receptor signaling pathway respiratory system process skeletal system morphogenesis smooth muscle tissue development vasculature development cytoplasm DNA binding zinc ion binding Mus musculus 3D-structure Acetylation Cytoplasm Metal-binding Phosphoprotein Reference proteome Ubl conjugation pathway Zinc Zinc-finger MAQETNQTPG MAQETNQTPGPMLCSTGCGFYGNPRTNGMCSVCYKEHLQRQQNSGRMSPMGTASGSNSPTSDSASVQRADAGLNNCEGAAGSTSEKSRNVPVAALPVTQQMTEMSISREDKITTPKTEVSEPVVTQPSPSVSQPSSSQSEEKAPELPKPKKNRCFMCRKKVGLTGFDCRCGNLFCGLHRYSDKHNCPYDYKAEAAAKIRKENPVVVAEKIQRI |
antiviral innate immune response apoptotic process cellular response to cAMP cellular response to peptide hormone stimulus negative regulation of cardiac muscle hypertrophy negative regulation of protein dephosphorylation negative regulation of protein import into nucleus regulation of protein kinase A signaling | lipid droplet; membrane; mitochondrial crista; mitochondrial outer membrane; mitochondrion; neuromuscular junction; postsynaptic membrane; postsynaptic specialization, intracellular component | beta-tubulin binding microtubule binding molecular adaptor activity protein kinase A regulatory subunit binding protein kinase binding protein phosphatase 2B binding protein phosphatase binding RNA binding | Rattus norvegicus | Alternative splicing Membrane Mitochondrion Mitochondrion outer membrane Phosphoprotein Reference proteome RNA-binding Transit peptide Transmembrane | MAIQFRSLFP | MAIQFRSLFPLALPGMLALLGWWWFFSRKKDRLSSNGKQVGTLKVGPAIEDRLPTEEACPGVLSVTPSVTQPPGKEEQRSMDRPLSDPPALPRTRQVRRRSESSGNLPSIVDTRLQAGQCSDENSKVVLSLMGDEAKSIPLGRPLFPKDLSFPYEAVEGCKQESALGRTPGRGWLSQCAASGENARETGGAEGTGDAVLGESVLEEGLLPQECVSEVEKSEFPILAPGGGGGEKVRSGPPQVDELLKKEEYIVGKLPSSFVGPVHSELVKDEGALVPQVKGSQDRSLARELDKDKTLPEKDQIEQTAFQIISQVILEATEEIRATTVGKTVAQVHPTPGTQPQGQEESCVPASQETSLGQEIPDPASTRTGATASPSAGAPPPKTYVSCLSSPLSGPTKDQKPKNSAHHISLAPCPPPVTPQRQSLDGASNPRGDDTFVTCTSNNSQSVLSVTSLGLCSDPVSTSRLEDSCTETISSSGDKAVTPPLPDSTEPFSNGVLKEELSDLGTEDGWTMDTEADHSGGSDGNSMDSVDSCCGLTKPDSPQTVQAGSNPKKVDLIIWEIEVPKHLVGRLIGKQGRYVSFLKQTSGAKIYISTLPYTQNIQICHIEGSQHHVDKALNLIGKKFKELNLTNIYAPPLPSLALPSLPMTSWLMLPDGITVEVIVVNQVNAGHLFVQQHTHPTFHALRSLDQQMYLCYSQPGIPTLPTPVEITVICAAPGADGAWWRAQVVASYEETNEVEIRYVDYGGYKRVKVDVLRQIRSDFVTLPFQGAEVLLDSVVPLSDDDHFSPEADAAMSEMTGNTALLAQVTSYSATGLPLIQLWSVVGDEVVLINRSLVERGLAQWVDSCYASL | antiviral innate immune response apoptotic process cellular response to cAMP cellular response to peptide hormone stimulus negative regulation of cardiac muscle hypertrophy negative regulation of protein dephosphorylation negative regulation of protein import into nucleus regulation of protein kinase A signaling lipid droplet; membrane; mitochondrial crista; mitochondrial outer membrane; mitochondrion; neuromuscular junction; postsynaptic membrane; postsynaptic specialization, intracellular component beta-tubulin binding microtubule binding molecular adaptor activity protein kinase A regulatory subunit binding protein kinase binding protein phosphatase 2B binding protein phosphatase binding RNA binding Rattus norvegicus Alternative splicing Membrane Mitochondrion Mitochondrion outer membrane Phosphoprotein Reference proteome RNA-binding Transit peptide Transmembrane MAIQFRSLFP MAIQFRSLFPLALPGMLALLGWWWFFSRKKDRLSSNGKQVGTLKVGPAIEDRLPTEEACPGVLSVTPSVTQPPGKEEQRSMDRPLSDPPALPRTRQVRRRSESSGNLPSIVDTRLQAGQCSDENSKVVLSLMGDEAKSIPLGRPLFPKDLSFPYEAVEGCKQESALGRTPGRGWLSQCAASGENARETGGAEGTGDAVLGESVLEEGLLPQECVSEVEKSEFPILAPGGGGGEKVRSGPPQVDELLKKEEYIVGKLPSSFVGPVHSELVKDEGALVPQVKGSQDRSLARELDKDKTLPEKDQIEQTAFQIISQVILEATEEIRATTVGKTVAQVHPTPGTQPQGQEESCVPASQETSLGQEIPDPASTRTGATASPSAGAPPPKTYVSCLSSPLSGPTKDQKPKNSAHHISLAPCPPPVTPQRQSLDGASNPRGDDTFVTCTSNNSQSVLSVTSLGLCSDPVSTSRLEDSCTETISSSGDKAVTPPLPDSTEPFSNGVLKEELSDLGTEDGWTMDTEADHSGGSDGNSMDSVDSCCGLTKPDSPQTVQAGSNPKKVDLIIWEIEVPKHLVGRLIGKQGRYVSFLKQTSGAKIYISTLPYTQNIQICHIEGSQHHVDKALNLIGKKFKELNLTNIYAPPLPSLALPSLPMTSWLMLPDGITVEVIVVNQVNAGHLFVQQHTHPTFHALRSLDQQMYLCYSQPGIPTLPTPVEITVICAAPGADGAWWRAQVVASYEETNEVEIRYVDYGGYKRVKVDVLRQIRSDFVTLPFQGAEVLLDSVVPLSDDDHFSPEADAAMSEMTGNTALLAQVTSYSATGLPLIQLWSVVGDEVVLINRSLVERGLAQWVDSCYASL |
cellular response to insulin stimulus insulin receptor signaling pathway intracellular signal transduction negative regulation of insulin receptor signaling pathway negative regulation of meiotic cell cycle process involved in oocyte maturation | cytoplasm; endosome; endosome membrane; intracellular membrane-bounded organelle; plasma membrane | molecular adaptor activity phosphoprotein binding protein-macromolecule adaptor activity receptor tyrosine kinase binding | Rattus norvegicus | Acetylation Cytoplasm Endosome Membrane Phosphoprotein Reference proteome SH2 domain | MTTSLQDGQS | MTTSLQDGQSAAGRAGAQDSPLAVQVCRVAQGKGDAQDPAQVPGLHALSPASDATRRGAMDRRKAKDLEVQETPSIPNPFPELCCSPLTSVLSAGLFPRSNSRKKQVIKVYSEDETSRALEVPSDVTARDVCQLLILKNHYVDDNSWTLFEHLSHTGVERTVEDHELLTEVLSHWVMEEDNKLYLRKNYAKYEFFKNPMYFFPEHMVSFATEMNGDRSLTQIPQVFLSSNTYPEIHGFLHAKEQGKKSWKKAYFFLRRSGLYFSTKGTSKEPRHLQFFSEFSTSNVYMSLAGKKKHGAPTPYGFCFKPTKAGGPRDLKMLCAEEDQSRMCWVTAIRLLKYGMQLYQNYMHPSQARSACSSQSVSPMRSVSENSLVAMDFSGQKTRVIDNPTEALSVAVEEGLAWRKKGCLRLGNHGSPTAPSQSSAVNMALHRSQPWFHHRISRDEAQQLITRQGPVDGVFLVRDSQSNPRTFVLSMSHGQKIKHFQIIPVEDDGEVFHTLDDGHTKFTDLIQLVEFYQLNKGVLPCKLKHYCARMAV | cellular response to insulin stimulus insulin receptor signaling pathway intracellular signal transduction negative regulation of insulin receptor signaling pathway negative regulation of meiotic cell cycle process involved in oocyte maturation cytoplasm; endosome; endosome membrane; intracellular membrane-bounded organelle; plasma membrane molecular adaptor activity phosphoprotein binding protein-macromolecule adaptor activity receptor tyrosine kinase binding Rattus norvegicus Acetylation Cytoplasm Endosome Membrane Phosphoprotein Reference proteome SH2 domain MTTSLQDGQS MTTSLQDGQSAAGRAGAQDSPLAVQVCRVAQGKGDAQDPAQVPGLHALSPASDATRRGAMDRRKAKDLEVQETPSIPNPFPELCCSPLTSVLSAGLFPRSNSRKKQVIKVYSEDETSRALEVPSDVTARDVCQLLILKNHYVDDNSWTLFEHLSHTGVERTVEDHELLTEVLSHWVMEEDNKLYLRKNYAKYEFFKNPMYFFPEHMVSFATEMNGDRSLTQIPQVFLSSNTYPEIHGFLHAKEQGKKSWKKAYFFLRRSGLYFSTKGTSKEPRHLQFFSEFSTSNVYMSLAGKKKHGAPTPYGFCFKPTKAGGPRDLKMLCAEEDQSRMCWVTAIRLLKYGMQLYQNYMHPSQARSACSSQSVSPMRSVSENSLVAMDFSGQKTRVIDNPTEALSVAVEEGLAWRKKGCLRLGNHGSPTAPSQSSAVNMALHRSQPWFHHRISRDEAQQLITRQGPVDGVFLVRDSQSNPRTFVLSMSHGQKIKHFQIIPVEDDGEVFHTLDDGHTKFTDLIQLVEFYQLNKGVLPCKLKHYCARMAV |
fat cell differentiation G1/S transition of mitotic cell cycle negative regulation of apoptotic process negative regulation of transcription by RNA polymerase II positive regulation of DNA-templated transcription positive regulation of proteasomal ubiquitin-dependent protein catabolic process positive regulation of protein localization to cell periphery positive regulation of protein sumoylation positive regulation of smooth muscle cell differentiation protein sumoylation protein-DNA complex assembly receptor signaling pathway via JAK-STAT regulation of cell population proliferation regulation of transcription by RNA polymerase II spermatogenesis visual learning | cytoplasm; cytoskeleton; nuclear periphery; nuclear speck; nucleoplasm; nucleus; PML body | DNA-binding transcription factor binding enzyme binding protein domain specific binding SUMO ligase activity SUMO transferase activity transcription cis-regulatory region binding transcription coregulator activity transcription corepressor activity ubiquitin protein ligase binding zinc ion binding | Mus musculus | Acetylation Cytoplasm Cytoskeleton DNA-binding Isopeptide bond Metal-binding Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation Transferase Ubl conjugation Ubl conjugation pathway Zinc Zinc-finger | MADSAELKQM | MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKELYRRRFPQKIMTPADLSIPNVHSSPMPPTLSPSTIPQLTYDGHPASSPLLPVSLLGPKHELELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRTYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDGSWAPMRSKKEVQEVTASYNGVDGCLSSTLEHQVASHNQSSNKNKKVEVIDLTIDSSSDEEEEEPPAKRTCPSLSPTSPLSNKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPMPYDLQGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSSRFFPYTSSQMFLDQLSAGGSTSLPATNGSSSGSNSSLVSSNSLRESHGHGVASRSSADTASIFGIIPDIISLD | fat cell differentiation G1/S transition of mitotic cell cycle negative regulation of apoptotic process negative regulation of transcription by RNA polymerase II positive regulation of DNA-templated transcription positive regulation of proteasomal ubiquitin-dependent protein catabolic process positive regulation of protein localization to cell periphery positive regulation of protein sumoylation positive regulation of smooth muscle cell differentiation protein sumoylation protein-DNA complex assembly receptor signaling pathway via JAK-STAT regulation of cell population proliferation regulation of transcription by RNA polymerase II spermatogenesis visual learning cytoplasm; cytoskeleton; nuclear periphery; nuclear speck; nucleoplasm; nucleus; PML body DNA-binding transcription factor binding enzyme binding protein domain specific binding SUMO ligase activity SUMO transferase activity transcription cis-regulatory region binding transcription coregulator activity transcription corepressor activity ubiquitin protein ligase binding zinc ion binding Mus musculus Acetylation Cytoplasm Cytoskeleton DNA-binding Isopeptide bond Metal-binding Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation Transferase Ubl conjugation Ubl conjugation pathway Zinc Zinc-finger MADSAELKQM MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKELYRRRFPQKIMTPADLSIPNVHSSPMPPTLSPSTIPQLTYDGHPASSPLLPVSLLGPKHELELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRTYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDGSWAPMRSKKEVQEVTASYNGVDGCLSSTLEHQVASHNQSSNKNKKVEVIDLTIDSSSDEEEEEPPAKRTCPSLSPTSPLSNKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPMPYDLQGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSSRFFPYTSSQMFLDQLSAGGSTSLPATNGSSSGSNSSLVSSNSLRESHGHGVASRSSADTASIFGIIPDIISLD |
cholesterol efflux cholesterol homeostasis cholesterol metabolic process cholesterol storage very-low-density lipoprotein particle assembly | brush border; endoplasmic reticulum; endoplasmic reticulum membrane; membrane | cholesterol binding cholesterol O-acyltransferase activity fatty-acyl-CoA binding sterol O-acyltransferase activity | Mus musculus | Acyltransferase Cholesterol metabolism Endoplasmic reticulum Lipid metabolism Membrane Oxidation Reference proteome Steroid metabolism Sterol metabolism Thioester bond Transferase Transmembrane Transmembrane helix Ubl conjugation | MQPKVPQLRR | MQPKVPQLRRREGLGEEQEKGARGGEGNARTHGTPDLVQWTRHMEAVKTQFLEQAQRELAELLDRALWEAMQAYPKQDRPLPSAAPDSTSKTQELHPGKRKVFITRKSLIDELMEVQHFRTIYHMFIAGLCVLIISTLAIDFIDEGRLMLEFDLLLFSFGQLPLALMTWVPMFLSTLLVPYQTLWLWARPRAGGAWMLGASLGCVLLAAHAVVLCVLPVHVSVRHELPPASRCVLVFEQVRLLMKSYSFLRETVPGIFCVRGGKGISPPSFSSYLYFLFCPTLIYRETYPRTPSIRWNYVAKNFAQVLGCLLYACFILGRLCVPVFANMSREPFSTRALLLSILHATGPGIFMLLLIFFAFLHCWLNAFAEMLRFGDRMFYRDWWNSTSFSNYYRTWNVVVHDWLYSYVYQDGLWLLGRRARGVAMLGVFLVSAVVHEYIFCFVLGFFYPVMLMLFLVFGGLLNFTMNDRHTGPAWNILMWTFLFMGQGIQVSLYCQEWYARRHCPLPQTTFWGMVTPRSWSCHP | cholesterol efflux cholesterol homeostasis cholesterol metabolic process cholesterol storage very-low-density lipoprotein particle assembly brush border; endoplasmic reticulum; endoplasmic reticulum membrane; membrane cholesterol binding cholesterol O-acyltransferase activity fatty-acyl-CoA binding sterol O-acyltransferase activity Mus musculus Acyltransferase Cholesterol metabolism Endoplasmic reticulum Lipid metabolism Membrane Oxidation Reference proteome Steroid metabolism Sterol metabolism Thioester bond Transferase Transmembrane Transmembrane helix Ubl conjugation MQPKVPQLRR MQPKVPQLRRREGLGEEQEKGARGGEGNARTHGTPDLVQWTRHMEAVKTQFLEQAQRELAELLDRALWEAMQAYPKQDRPLPSAAPDSTSKTQELHPGKRKVFITRKSLIDELMEVQHFRTIYHMFIAGLCVLIISTLAIDFIDEGRLMLEFDLLLFSFGQLPLALMTWVPMFLSTLLVPYQTLWLWARPRAGGAWMLGASLGCVLLAAHAVVLCVLPVHVSVRHELPPASRCVLVFEQVRLLMKSYSFLRETVPGIFCVRGGKGISPPSFSSYLYFLFCPTLIYRETYPRTPSIRWNYVAKNFAQVLGCLLYACFILGRLCVPVFANMSREPFSTRALLLSILHATGPGIFMLLLIFFAFLHCWLNAFAEMLRFGDRMFYRDWWNSTSFSNYYRTWNVVVHDWLYSYVYQDGLWLLGRRARGVAMLGVFLVSAVVHEYIFCFVLGFFYPVMLMLFLVFGGLLNFTMNDRHTGPAWNILMWTFLFMGQGIQVSLYCQEWYARRHCPLPQTTFWGMVTPRSWSCHP |
glutathione transport monoatomic ion transport prostaglandin transport quaternary ammonium group transport response to toxic substance | apical plasma membrane; basolateral plasma membrane | antiporter activity organic anion transmembrane transporter activity prostaglandin transmembrane transporter activity protein kinase C binding quaternary ammonium group transmembrane transporter activity solute:inorganic anion antiporter activity xenobiotic transmembrane transporter activity | Mus musculus | Cell membrane Detoxification Glycoprotein Ion transport Lipid transport Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport | MTFSEILDRV | MTFSEILDRVGSMGPFQYLHVTLLALPILGIANHNLLQIFTATTPDHHCRPPPNASLEPWVLPLGPNGKPEKCLRFVHLPNASLPNDTQGATEPCLDGWIYNSTRDTIVTEWDLVCGSNKLKEMAQSVFMAGILVGGPVFGELSDRFGRKPILTWSYLLLAASGSSAAFSPSLTVYMIFRFLCGCSISGISLSTIILNVEWVPTSTRAISSTTIGYCYTIGQFILPGLAYAVPQWRWLQLSVSAAFFIFSLLSWWVPESIRWLVLSGKFSKALKTLQRVATFNGKKEEGEKLTVEELKFNLQKDITSAKVKYGLSDLFRVSILRRVTFCLSLAWFATGFAYYSLAMGVEEFGVNIYILQIIFGGVDIPAKFITILSISYLGRRITQGFLLILAGVAILALIFVSSEMQLLRTALAVFGKGCLSGSFSCLFLYTSELYPTVLRQTGMGISNIWARVGSMIAPLVKITGELQPFIPNVIFGTMTLLGGSAAFFLLETLNRPLPETIEDIQDWYQQTKKTKQEPEAEKASQTIPLKTGGP | glutathione transport monoatomic ion transport prostaglandin transport quaternary ammonium group transport response to toxic substance apical plasma membrane; basolateral plasma membrane antiporter activity organic anion transmembrane transporter activity prostaglandin transmembrane transporter activity protein kinase C binding quaternary ammonium group transmembrane transporter activity solute:inorganic anion antiporter activity xenobiotic transmembrane transporter activity Mus musculus Cell membrane Detoxification Glycoprotein Ion transport Lipid transport Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport MTFSEILDRV MTFSEILDRVGSMGPFQYLHVTLLALPILGIANHNLLQIFTATTPDHHCRPPPNASLEPWVLPLGPNGKPEKCLRFVHLPNASLPNDTQGATEPCLDGWIYNSTRDTIVTEWDLVCGSNKLKEMAQSVFMAGILVGGPVFGELSDRFGRKPILTWSYLLLAASGSSAAFSPSLTVYMIFRFLCGCSISGISLSTIILNVEWVPTSTRAISSTTIGYCYTIGQFILPGLAYAVPQWRWLQLSVSAAFFIFSLLSWWVPESIRWLVLSGKFSKALKTLQRVATFNGKKEEGEKLTVEELKFNLQKDITSAKVKYGLSDLFRVSILRRVTFCLSLAWFATGFAYYSLAMGVEEFGVNIYILQIIFGGVDIPAKFITILSISYLGRRITQGFLLILAGVAILALIFVSSEMQLLRTALAVFGKGCLSGSFSCLFLYTSELYPTVLRQTGMGISNIWARVGSMIAPLVKITGELQPFIPNVIFGTMTLLGGSAAFFLLETLNRPLPETIEDIQDWYQQTKKTKQEPEAEKASQTIPLKTGGP |
neuron development neurotransmitter secretion regulation of short-term neuronal synaptic plasticity regulation of synaptic vesicle cycle regulation of synaptic vesicle exocytosis synapse organization synaptic vesicle clustering synaptic vesicle cycle | axon; cell body; clathrin-sculpted glutamate transport vesicle membrane; cytoskeleton; dendrite; extrinsic component of synaptic vesicle membrane; Golgi apparatus; myelin sheath; postsynaptic density; presynapse; presynaptic active zone; Schaffer collateral - CA1 synapse; synapse; synaptic vesicle; synaptic vesicle membrane; synaptonemal complex | actin binding ATP binding calcium-dependent protein binding identical protein binding protein kinase binding | Mus musculus | Actin-binding Alternative splicing Cell projection Cytoplasmic vesicle Direct protein sequencing Glycoprotein Golgi apparatus Methylation Phosphoprotein Reference proteome Repeat Synapse | MNYLRRRLSD | MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPSAASPGATPGSATASAERASTAAPVASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAAARVLLVIDEPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVVRSLKPDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKLGTEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKTYATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDTCSEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMTQALPRQPQRDASPGRGSHSQSSSPGALTLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTAAPQQSASQATPVTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGAPQATRQASISGPAPTKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPGPRTGPPTTQQPRPSGPGPAGRPAKPQLAQKPSQDVPPPITAAAGGPPHPQLNKSQSLTNAFNLPEPAPPRPSLSQDEVKAETIRSLRKSFASLFSD | neuron development neurotransmitter secretion regulation of short-term neuronal synaptic plasticity regulation of synaptic vesicle cycle regulation of synaptic vesicle exocytosis synapse organization synaptic vesicle clustering synaptic vesicle cycle axon; cell body; clathrin-sculpted glutamate transport vesicle membrane; cytoskeleton; dendrite; extrinsic component of synaptic vesicle membrane; Golgi apparatus; myelin sheath; postsynaptic density; presynapse; presynaptic active zone; Schaffer collateral - CA1 synapse; synapse; synaptic vesicle; synaptic vesicle membrane; synaptonemal complex actin binding ATP binding calcium-dependent protein binding identical protein binding protein kinase binding Mus musculus Actin-binding Alternative splicing Cell projection Cytoplasmic vesicle Direct protein sequencing Glycoprotein Golgi apparatus Methylation Phosphoprotein Reference proteome Repeat Synapse MNYLRRRLSD MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPSAASPGATPGSATASAERASTAAPVASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAAARVLLVIDEPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVVRSLKPDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKLGTEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKTYATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDTCSEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMTQALPRQPQRDASPGRGSHSQSSSPGALTLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTAAPQQSASQATPVTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGAPQATRQASISGPAPTKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPGPRTGPPTTQQPRPSGPGPAGRPAKPQLAQKPSQDVPPPITAAAGGPPHPQLNKSQSLTNAFNLPEPAPPRPSLSQDEVKAETIRSLRKSFASLFSD |
B cell differentiation cartilage development chromatin organization chromatin remodeling DNA-templated transcription double-strand break repair via classical nonhomologous end joining erythrocyte maturation fat cell differentiation negative regulation of androgen receptor signaling pathway negative regulation of DNA-templated transcription negative regulation of Notch signaling pathway negative regulation of transcription by RNA polymerase II negative regulation of transforming growth factor beta receptor signaling pathway positive regulation of NF-kappaB transcription factor activity protein localization to nucleus regulation of alternative mRNA splicing, via spliceosome regulation of apoptotic process regulation of DNA-binding transcription factor activity regulation of DNA-templated transcription regulation of glycolytic process regulation of osteoclast differentiation regulation of transcription by RNA polymerase II regulation of transcription regulatory region DNA binding | cytoplasm; nucleus | DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor binding DNA-binding transcription repressor activity, RNA polymerase II-specific histone acetyltransferase binding metal ion binding nuclear androgen receptor binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA binding SMAD binding transcription corepressor binding | Mus musculus | Alternative splicing Developmental protein Differentiation DNA damage DNA repair DNA-binding Isopeptide bond Metal-binding Nucleus Phosphoprotein Reference proteome Repeat Repressor Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | MAGGVDGPIG | MAGGVDGPIGIPFPDHSSDILSGLNEQRTQGLLCDVVILVEGREFPTHRSVLAACSQYFKKLFTSGAVVDQQNVYEIDFVSAEALTALMDFAYTATLTVSTANVGDILSAARLLEIPAVSHVCADLLERQILAADDVGDASQPDGAGPTDQRNLLRAKEYLEFFRSNPMNSLPPTAFPWSGFGAPDDDLDATKEAVAAAVAAVAAGDCNGLDFYGPGPPADRPPAGDGDEGDSTPGLWPERDEDAPPGGLFPPPTAPPATTQNGHYGRAGAGTGEEEAAALSEAAPEPGDSPGFLSGAAEGEDGDAADVDGLAASTLLQQMMSSVGRAGDSDEESRTDDKGVMDYYLKYFSGAHEGDVYPAWSQKGEKKIRAKAFQKCPICEKVIQGAGKLPRHIRTHTGEKPYECNICKVRFTRQDKLKVHMRKHTGEKPYLCQQCGAAFAHNYDLKNHMRVHTGLRPYQCDSCCKTFVRSDHLHRHLKKDGCNGVPSRRGRKPRVRGVPPDVPAGAGAPPGLPDAPRNGQEKHFKDEEEDEEEASPDGSGRLNVAGSGGDDGAGGPAVATAEGNFAT | B cell differentiation cartilage development chromatin organization chromatin remodeling DNA-templated transcription double-strand break repair via classical nonhomologous end joining erythrocyte maturation fat cell differentiation negative regulation of androgen receptor signaling pathway negative regulation of DNA-templated transcription negative regulation of Notch signaling pathway negative regulation of transcription by RNA polymerase II negative regulation of transforming growth factor beta receptor signaling pathway positive regulation of NF-kappaB transcription factor activity protein localization to nucleus regulation of alternative mRNA splicing, via spliceosome regulation of apoptotic process regulation of DNA-binding transcription factor activity regulation of DNA-templated transcription regulation of glycolytic process regulation of osteoclast differentiation regulation of transcription by RNA polymerase II regulation of transcription regulatory region DNA binding cytoplasm; nucleus DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor binding DNA-binding transcription repressor activity, RNA polymerase II-specific histone acetyltransferase binding metal ion binding nuclear androgen receptor binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA binding SMAD binding transcription corepressor binding Mus musculus Alternative splicing Developmental protein Differentiation DNA damage DNA repair DNA-binding Isopeptide bond Metal-binding Nucleus Phosphoprotein Reference proteome Repeat Repressor Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger MAGGVDGPIG MAGGVDGPIGIPFPDHSSDILSGLNEQRTQGLLCDVVILVEGREFPTHRSVLAACSQYFKKLFTSGAVVDQQNVYEIDFVSAEALTALMDFAYTATLTVSTANVGDILSAARLLEIPAVSHVCADLLERQILAADDVGDASQPDGAGPTDQRNLLRAKEYLEFFRSNPMNSLPPTAFPWSGFGAPDDDLDATKEAVAAAVAAVAAGDCNGLDFYGPGPPADRPPAGDGDEGDSTPGLWPERDEDAPPGGLFPPPTAPPATTQNGHYGRAGAGTGEEEAAALSEAAPEPGDSPGFLSGAAEGEDGDAADVDGLAASTLLQQMMSSVGRAGDSDEESRTDDKGVMDYYLKYFSGAHEGDVYPAWSQKGEKKIRAKAFQKCPICEKVIQGAGKLPRHIRTHTGEKPYECNICKVRFTRQDKLKVHMRKHTGEKPYLCQQCGAAFAHNYDLKNHMRVHTGLRPYQCDSCCKTFVRSDHLHRHLKKDGCNGVPSRRGRKPRVRGVPPDVPAGAGAPPGLPDAPRNGQEKHFKDEEEDEEEASPDGSGRLNVAGSGGDDGAGGPAVATAEGNFAT |
branchiomeric skeletal muscle development cellular response to leukemia inhibitory factor diaphragm development negative regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II roof of mouth development skeletal muscle tissue development | nucleoplasm; nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Mus musculus | DNA-binding Nucleus Reference proteome Repressor Transcription Transcription regulation | MSTGSVSDPE | MSTGSVSDPEDSEMRGLQRVYPAPASKRPPLLRMERGYGSPSDISSAEEEDGEEEPGSLGAAGGCKRKRLRGADAGGAGGRAGGAGKKPLPPKGSAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYEDSYVHPVNLTWPFVVSGRPDSDSKDVSAANRLCGTSA | branchiomeric skeletal muscle development cellular response to leukemia inhibitory factor diaphragm development negative regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II roof of mouth development skeletal muscle tissue development nucleoplasm; nucleus DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding Mus musculus DNA-binding Nucleus Reference proteome Repressor Transcription Transcription regulation MSTGSVSDPE MSTGSVSDPEDSEMRGLQRVYPAPASKRPPLLRMERGYGSPSDISSAEEEDGEEEPGSLGAAGGCKRKRLRGADAGGAGGRAGGAGKKPLPPKGSAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYEDSYVHPVNLTWPFVVSGRPDSDSKDVSAANRLCGTSA |
action potential initiation apoptosome assembly cellular response to ammonium ion cellular response to calcium ion cellular response to xenobiotic stimulus endocytosis establishment of localization in cell excitatory chemical synaptic transmission exocytosis ganglion development gene expression inhibitory chemical synaptic transmission membrane hyperpolarization mitochondrial depolarization monoatomic ion transmembrane transport nerve development neuron apoptotic process neuron differentiation neuron remodeling neuronal action potential oligodendrocyte development potassium ion transmembrane transport protein import into nucleus protein targeting protein transport protein-containing complex assembly psychomotor behavior regulation of action potential firing threshold regulation of synaptic plasticity response to auditory stimulus response to mechanical stimulus response to organic cyclic compound sensory perception of sound substantia propria of cornea development | axon initial segment; cell surface; dendrite; mitochondrion; neuronal cell body; node of Ranvier; plasma membrane; somatodendritic compartment; synapse; voltage-gated potassium channel complex | calmodulin binding potassium channel activity protein kinase binding transmembrane transporter binding ubiquitin protein ligase binding voltage-gated monoatomic ion channel activity voltage-gated potassium channel activity | Rattus norvegicus | Alternative splicing Cell membrane Ion channel Ion transport Membrane Phosphoprotein Potassium Potassium channel Potassium transport Reference proteome Transmembrane Transmembrane helix Transport Ubl conjugation Voltage-gated channel | MGLKARRAAG | MGLKARRAAGAAGGGGGEGGGGGGGAANPAGGDSAVAGDEERKVGLAPGDVEQVTLALGTGADKDGTLLLEGGGREEGQRRTPQGIGLLAKTPLSRPVKRNNAKYRRIQTLIYDALERPRGWALLYHALVFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATSLRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEMDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRKPAAELIQAAWRYYATNPNRLDLVATWRFYESVVSFPFFRKEQLEAAASQKLGLLDRVRLSNPRGSNTKGKLFTPLNVDAIEESPSKEPKPVGLNNKERFRTAFRMKAYAFWQSSEDAGTGDPMTEDRGYGNDFLIEDMIPTLKAAIRAVRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGSAFTYPSQQSPRNEPYVARAATSETEDQSMMGKFVKVERQVHDMGKKLDFLVDMHMQHMERLQVHVTEYYPTKGASSPAEGEKKEDNRYSDLKTIICNYSESGPPDPPYSFHQVPIDRVGPYGFFAHDPVKLTRGGPSSTKAQANLPSSGSTYAERPTVLPILTLLDSCVSYHSQTELQGPYSDHISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFGPSGGSSWMREKRYLAEGETDTDTDPFTPSGSMPMSSTGDGISDSIWTPSNKPT | action potential initiation apoptosome assembly cellular response to ammonium ion cellular response to calcium ion cellular response to xenobiotic stimulus endocytosis establishment of localization in cell excitatory chemical synaptic transmission exocytosis ganglion development gene expression inhibitory chemical synaptic transmission membrane hyperpolarization mitochondrial depolarization monoatomic ion transmembrane transport nerve development neuron apoptotic process neuron differentiation neuron remodeling neuronal action potential oligodendrocyte development potassium ion transmembrane transport protein import into nucleus protein targeting protein transport protein-containing complex assembly psychomotor behavior regulation of action potential firing threshold regulation of synaptic plasticity response to auditory stimulus response to mechanical stimulus response to organic cyclic compound sensory perception of sound substantia propria of cornea development axon initial segment; cell surface; dendrite; mitochondrion; neuronal cell body; node of Ranvier; plasma membrane; somatodendritic compartment; synapse; voltage-gated potassium channel complex calmodulin binding potassium channel activity protein kinase binding transmembrane transporter binding ubiquitin protein ligase binding voltage-gated monoatomic ion channel activity voltage-gated potassium channel activity Rattus norvegicus Alternative splicing Cell membrane Ion channel Ion transport Membrane Phosphoprotein Potassium Potassium channel Potassium transport Reference proteome Transmembrane Transmembrane helix Transport Ubl conjugation Voltage-gated channel MGLKARRAAG MGLKARRAAGAAGGGGGEGGGGGGGAANPAGGDSAVAGDEERKVGLAPGDVEQVTLALGTGADKDGTLLLEGGGREEGQRRTPQGIGLLAKTPLSRPVKRNNAKYRRIQTLIYDALERPRGWALLYHALVFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATSLRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEMDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRKPAAELIQAAWRYYATNPNRLDLVATWRFYESVVSFPFFRKEQLEAAASQKLGLLDRVRLSNPRGSNTKGKLFTPLNVDAIEESPSKEPKPVGLNNKERFRTAFRMKAYAFWQSSEDAGTGDPMTEDRGYGNDFLIEDMIPTLKAAIRAVRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGSAFTYPSQQSPRNEPYVARAATSETEDQSMMGKFVKVERQVHDMGKKLDFLVDMHMQHMERLQVHVTEYYPTKGASSPAEGEKKEDNRYSDLKTIICNYSESGPPDPPYSFHQVPIDRVGPYGFFAHDPVKLTRGGPSSTKAQANLPSSGSTYAERPTVLPILTLLDSCVSYHSQTELQGPYSDHISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFGPSGGSSWMREKRYLAEGETDTDTDPFTPSGSMPMSSTGDGISDSIWTPSNKPT |
blood coagulation positive regulation of TOR signaling proteolysis | extracellular space | calcium ion binding phospholipid binding serine-type endopeptidase activity | Mus musculus | Blood coagulation Calcium Cleavage on pair of basic residues Disulfide bond EGF-like domain Gamma-carboxyglutamic acid Glycoprotein Hemostasis Hydrolase Hydroxylation Protease Reference proteome Repeat Secreted Serine protease Signal Zymogen | MGSPVQLSLL | MGSPVQLSLLCVVLASLLLPGKGVFINRERANNVLARTRRANSFFEEFKKGNLERECMEEICSYEEVREIFEDDEKTKEYWTKYKDGDQCESSPCQNQGACRDGIGGYTCTCSEGFEGKNCELFVRKLCRLDNGDCDQFCREEQNSVVCSCASGYFLGNDGKSCISTAPFPCGKITTGRRKRSVALNTSDSELDLEDALLDEDFLSPTENPIELLNLNETQPERSSDDLVRIVGGRECKDGECPWQALLINEDNEGFCGGTILNEFYILTAAHCLHQARRFKVRVGDRNTEKEEGNEMVHEVDVVIKHNKFQRDTYDYDIAVLRLKTPITFRMNVAPACLPQKDWAESTLMTQKTGIVSGFGRTHEKGRQSNILKMLEVPYVDRNTCKLSTSFSITQNMFCAGYEAKLEDACQGDSGGPHVTRFKNTYYVTGIVSWGEGCARKGKYGIYTKVTTFLKWIDRSMKARVGPTAETPRTAGPPN | blood coagulation positive regulation of TOR signaling proteolysis extracellular space calcium ion binding phospholipid binding serine-type endopeptidase activity Mus musculus Blood coagulation Calcium Cleavage on pair of basic residues Disulfide bond EGF-like domain Gamma-carboxyglutamic acid Glycoprotein Hemostasis Hydrolase Hydroxylation Protease Reference proteome Repeat Secreted Serine protease Signal Zymogen MGSPVQLSLL MGSPVQLSLLCVVLASLLLPGKGVFINRERANNVLARTRRANSFFEEFKKGNLERECMEEICSYEEVREIFEDDEKTKEYWTKYKDGDQCESSPCQNQGACRDGIGGYTCTCSEGFEGKNCELFVRKLCRLDNGDCDQFCREEQNSVVCSCASGYFLGNDGKSCISTAPFPCGKITTGRRKRSVALNTSDSELDLEDALLDEDFLSPTENPIELLNLNETQPERSSDDLVRIVGGRECKDGECPWQALLINEDNEGFCGGTILNEFYILTAAHCLHQARRFKVRVGDRNTEKEEGNEMVHEVDVVIKHNKFQRDTYDYDIAVLRLKTPITFRMNVAPACLPQKDWAESTLMTQKTGIVSGFGRTHEKGRQSNILKMLEVPYVDRNTCKLSTSFSITQNMFCAGYEAKLEDACQGDSGGPHVTRFKNTYYVTGIVSWGEGCARKGKYGIYTKVTTFLKWIDRSMKARVGPTAETPRTAGPPN |
exocytosis maintenance of epithelial cell apical/basal polarity neurotransmitter secretion protein localization to basolateral plasma membrane protein transport | basolateral plasma membrane; bicellular tight junction; cell-cell junction; MPP7-DLG1-LIN7 complex; plasma membrane; postsynaptic density membrane; presynapse; synapse; transport vesicle membrane | L27 domain binding PDZ domain binding protein domain specific binding protein kinase binding | Mus musculus | 3D-structure Cell junction Cell membrane Exocytosis Membrane Postsynaptic cell membrane Protein transport Reference proteome Synapse Tight junction Transport | MAALVEPLGL | MAALVEPLGLERDVSRAVELLERLQRSGELPPQKLQALQRVLQSRFCSAIREVYEQLYDTLDITGSAEVRAHATAKATVAAFTASEGHAHPRVVELPKTDEGLGFNIMGGKEQNSPIYISRVIPGGVADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGSVKLVVRYTPRVLEEMEARFEKMRSARRRQQHHSYTSLESRG | exocytosis maintenance of epithelial cell apical/basal polarity neurotransmitter secretion protein localization to basolateral plasma membrane protein transport basolateral plasma membrane; bicellular tight junction; cell-cell junction; MPP7-DLG1-LIN7 complex; plasma membrane; postsynaptic density membrane; presynapse; synapse; transport vesicle membrane L27 domain binding PDZ domain binding protein domain specific binding protein kinase binding Mus musculus 3D-structure Cell junction Cell membrane Exocytosis Membrane Postsynaptic cell membrane Protein transport Reference proteome Synapse Tight junction Transport MAALVEPLGL MAALVEPLGLERDVSRAVELLERLQRSGELPPQKLQALQRVLQSRFCSAIREVYEQLYDTLDITGSAEVRAHATAKATVAAFTASEGHAHPRVVELPKTDEGLGFNIMGGKEQNSPIYISRVIPGGVADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGSVKLVVRYTPRVLEEMEARFEKMRSARRRQQHHSYTSLESRG |
exocytosis maintenance of epithelial cell apical/basal polarity morphogenesis of an epithelial sheet neurotransmitter secretion protein localization to basolateral plasma membrane protein transport | basolateral plasma membrane; bicellular tight junction; cell-cell junction; cytoplasm; glutamatergic synapse; MPP7-DLG1-LIN7 complex; plasma membrane; postsynaptic density membrane; presynapse; synapse; transport vesicle membrane | cytoskeletal protein binding L27 domain binding PDZ domain binding protein domain specific binding | Mus musculus | Acetylation Cell junction Cell membrane Direct protein sequencing Exocytosis Membrane Postsynaptic cell membrane Protein transport Reference proteome Synapse Tight junction Transport | MAALGEPVRL | MAALGEPVRLERDICRAIELLEKLQRSGEVPPQKLQALQRVLQSEFCNAVREVYEHVYETVDISSSPEVRANATAKATVAAFAASEGHSHPRVVELPKTEEGLGFNIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVVRYTPKVLEEMESRFEKMRSAKRRQQT | exocytosis maintenance of epithelial cell apical/basal polarity morphogenesis of an epithelial sheet neurotransmitter secretion protein localization to basolateral plasma membrane protein transport basolateral plasma membrane; bicellular tight junction; cell-cell junction; cytoplasm; glutamatergic synapse; MPP7-DLG1-LIN7 complex; plasma membrane; postsynaptic density membrane; presynapse; synapse; transport vesicle membrane cytoskeletal protein binding L27 domain binding PDZ domain binding protein domain specific binding Mus musculus Acetylation Cell junction Cell membrane Direct protein sequencing Exocytosis Membrane Postsynaptic cell membrane Protein transport Reference proteome Synapse Tight junction Transport MAALGEPVRL MAALGEPVRLERDICRAIELLEKLQRSGEVPPQKLQALQRVLQSEFCNAVREVYEHVYETVDISSSPEVRANATAKATVAAFAASEGHSHPRVVELPKTEEGLGFNIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVVRYTPKVLEEMESRFEKMRSAKRRQQT |
ceramide metabolic process phospholipid dephosphorylation phospholipid metabolic process signal transduction sphingosine metabolic process | apical plasma membrane; caveola; membrane; membrane raft; plasma membrane | ceramide-1-phosphate phosphatase activity diacylglycerol diphosphate phosphatase activity phosphatidate phosphatase activity sphingosine-1-phosphate phosphatase activity | Cavia porcellus | Alternative splicing Cell membrane Glycoprotein Hydrolase Lipid metabolism Membrane Reference proteome Transmembrane Transmembrane helix | MFDKARLPYV | MFDKARLPYVALDVLCVVLAGLPFAILTSRHTPFQRGIFCNDESIKYPYKEDTIPYALLGGIMIPFSIVVMIIGETLSVYCNLLHSNSFIRNNYIATIYKSIGTFLFGAAASQSLTDIAKYSIGRLRPHFLSVCDPDWSKVNCSDGYIEYYVCRGNAEKVKEGRLSFYSGHSSFSMYCMVFVALYLQARMKGDWARLLRPTLQFGLVAASIYVGLSRISDYKHHWSDVLTGLIQGAIVAILVAVYVSDFFKARNSPFQERKEEDSHTTLHETPTAGNHYRSNHQP | ceramide metabolic process phospholipid dephosphorylation phospholipid metabolic process signal transduction sphingosine metabolic process apical plasma membrane; caveola; membrane; membrane raft; plasma membrane ceramide-1-phosphate phosphatase activity diacylglycerol diphosphate phosphatase activity phosphatidate phosphatase activity sphingosine-1-phosphate phosphatase activity Cavia porcellus Alternative splicing Cell membrane Glycoprotein Hydrolase Lipid metabolism Membrane Reference proteome Transmembrane Transmembrane helix MFDKARLPYV MFDKARLPYVALDVLCVVLAGLPFAILTSRHTPFQRGIFCNDESIKYPYKEDTIPYALLGGIMIPFSIVVMIIGETLSVYCNLLHSNSFIRNNYIATIYKSIGTFLFGAAASQSLTDIAKYSIGRLRPHFLSVCDPDWSKVNCSDGYIEYYVCRGNAEKVKEGRLSFYSGHSSFSMYCMVFVALYLQARMKGDWARLLRPTLQFGLVAASIYVGLSRISDYKHHWSDVLTGLIQGAIVAILVAVYVSDFFKARNSPFQERKEEDSHTTLHETPTAGNHYRSNHQP |
acrosome reaction fructose 6-phosphate metabolic process fructose biosynthetic process generation of precursor metabolites and energy glucosamine catabolic process glucosamine metabolic process N-acetylglucosamine catabolic process N-acetylneuraminate catabolic process UDP-N-acetylglucosamine biosynthetic process | cytoplasm | glucosamine-6-phosphate deaminase activity identical protein binding isomerase activity | Mus musculus | Carbohydrate metabolism Cytoplasm Hydrolase Isomerase Phosphoprotein Reference proteome | MKLIILEHYS | MKLIILEHYSQASEWAAKYIRNRIIQFNPGPDKYFTLGLPTGSTPLGCYQKLIEYYKNGDLSFQYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAADLQAECDAFEEKIQAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGDLAKVPTMALTVGVGTVMDAKEVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCDEDATLELKVKTVKYFKGLMLVHNKLVDPLYSIKEKEIQKSQSAKKPYSD | acrosome reaction fructose 6-phosphate metabolic process fructose biosynthetic process generation of precursor metabolites and energy glucosamine catabolic process glucosamine metabolic process N-acetylglucosamine catabolic process N-acetylneuraminate catabolic process UDP-N-acetylglucosamine biosynthetic process cytoplasm glucosamine-6-phosphate deaminase activity identical protein binding isomerase activity Mus musculus Carbohydrate metabolism Cytoplasm Hydrolase Isomerase Phosphoprotein Reference proteome MKLIILEHYS MKLIILEHYSQASEWAAKYIRNRIIQFNPGPDKYFTLGLPTGSTPLGCYQKLIEYYKNGDLSFQYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAADLQAECDAFEEKIQAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGDLAKVPTMALTVGVGTVMDAKEVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCDEDATLELKVKTVKYFKGLMLVHNKLVDPLYSIKEKEIQKSQSAKKPYSD |
bile acid biosynthetic process positive regulation of intestinal cholesterol absorption | endoplasmic reticulum membrane | 5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase activity 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity heme binding iron ion binding sterol 12-alpha-hydroxylase activity | Mus musculus | Endoplasmic reticulum Heme Iron Lipid biosynthesis Lipid metabolism Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Phosphoprotein Reference proteome Steroid biosynthesis Transmembrane Transmembrane helix | MTLWCTVLGA | MTLWCTVLGALLTVVGCLCLSLLLRHRRPWEPPLDKGFVPWLGHSMAFRKNMFEFLKGMRAKHGDVFTVQLGGQYFTFVMDPLSFGPIIKNTEKALDFQSYAKELVLKVFGYQSVDGDHRMIHLASTKHLMGQGLEELNQAMLDSLSLVMLGPKGSSLGASSWCEDGLFHFCYRILFKAGFLSLFGYTKDKQQDLDEADELFRKFRRFDFLFPRFVYSLLGPREWVEVSQLQRLFHQRLSVEQNLEKDGISCWLGYMLQFLREQGIASSMQDKFNFMMLWASQGNTGPTCFWVLLFLLKHQDAMKAVREEATRVMGKARLEAKKSFTFTPSALKHTPVLDSVMEESLRLCATPTLLRVVQEDYVLKMASGQEYQIRRGDKVALFPYLSVHMDPDIHPEPTAFKYDRFLNPDGTRKVDFYKSGKKIHHYSMPWGSGVSKCPGRFFALSEMKTFVLLMIMYFDFKLVDPDIPVPPIDPRRWGFGTSQPSHEVRFLYRLKPVQ | bile acid biosynthetic process positive regulation of intestinal cholesterol absorption endoplasmic reticulum membrane 5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase activity 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity heme binding iron ion binding sterol 12-alpha-hydroxylase activity Mus musculus Endoplasmic reticulum Heme Iron Lipid biosynthesis Lipid metabolism Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Phosphoprotein Reference proteome Steroid biosynthesis Transmembrane Transmembrane helix MTLWCTVLGA MTLWCTVLGALLTVVGCLCLSLLLRHRRPWEPPLDKGFVPWLGHSMAFRKNMFEFLKGMRAKHGDVFTVQLGGQYFTFVMDPLSFGPIIKNTEKALDFQSYAKELVLKVFGYQSVDGDHRMIHLASTKHLMGQGLEELNQAMLDSLSLVMLGPKGSSLGASSWCEDGLFHFCYRILFKAGFLSLFGYTKDKQQDLDEADELFRKFRRFDFLFPRFVYSLLGPREWVEVSQLQRLFHQRLSVEQNLEKDGISCWLGYMLQFLREQGIASSMQDKFNFMMLWASQGNTGPTCFWVLLFLLKHQDAMKAVREEATRVMGKARLEAKKSFTFTPSALKHTPVLDSVMEESLRLCATPTLLRVVQEDYVLKMASGQEYQIRRGDKVALFPYLSVHMDPDIHPEPTAFKYDRFLNPDGTRKVDFYKSGKKIHHYSMPWGSGVSKCPGRFFALSEMKTFVLLMIMYFDFKLVDPDIPVPPIDPRRWGFGTSQPSHEVRFLYRLKPVQ |
cell population proliferation mitochondrial protein catabolic process mitochondrial protein processing mitochondrion organization negative regulation of apoptotic process protein hexamerization protein quality control for misfolded or incompletely synthesized proteins | mitochondrial inner membrane; mitochondrion; nuclear body | ATP binding ATP hydrolysis activity ATP-dependent peptidase activity metal ion binding metalloendopeptidase activity | Mus musculus | ATP-binding Hydrolase Membrane Metal-binding Metalloprotease Mitochondrion Mitochondrion inner membrane Nucleotide-binding Protease Reference proteome Transmembrane Transmembrane helix Zinc | MFSLSSTVQP | MFSLSSTVQPQVTIPLSHLINAFHSPKNISVSVNTPVSQKQHRDTVPEHEAPSSEPVLNLRDLGLSELKIGQIDKMVENLLPGFYKDKRVSSCWHTSHISAQSFFENKYGHLDMFSTLRSSSLYRQHPKTLRSICSDLQYFPVFIQSRGFKTLKSRTRRLQSTSERLVEAQNIAPSFVKGFLLRDRGTDLESLDKLMKTKNIPEAHQDAFKTGFAEGFLKAQALTQKTNDSLRRTRLILFVLLLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKNPQKFTVLGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDKSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHESGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGGRVAEELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTGKLSPETQSAIEQEIRILLRESYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR | cell population proliferation mitochondrial protein catabolic process mitochondrial protein processing mitochondrion organization negative regulation of apoptotic process protein hexamerization protein quality control for misfolded or incompletely synthesized proteins mitochondrial inner membrane; mitochondrion; nuclear body ATP binding ATP hydrolysis activity ATP-dependent peptidase activity metal ion binding metalloendopeptidase activity Mus musculus ATP-binding Hydrolase Membrane Metal-binding Metalloprotease Mitochondrion Mitochondrion inner membrane Nucleotide-binding Protease Reference proteome Transmembrane Transmembrane helix Zinc MFSLSSTVQP MFSLSSTVQPQVTIPLSHLINAFHSPKNISVSVNTPVSQKQHRDTVPEHEAPSSEPVLNLRDLGLSELKIGQIDKMVENLLPGFYKDKRVSSCWHTSHISAQSFFENKYGHLDMFSTLRSSSLYRQHPKTLRSICSDLQYFPVFIQSRGFKTLKSRTRRLQSTSERLVEAQNIAPSFVKGFLLRDRGTDLESLDKLMKTKNIPEAHQDAFKTGFAEGFLKAQALTQKTNDSLRRTRLILFVLLLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKNPQKFTVLGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDKSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHESGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGGRVAEELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTGKLSPETQSAIEQEIRILLRESYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR |
cellular response to type II interferon early endosome to late endosome transport endosome to lysosome transport intracellular protein transport regulation of protein localization to plasma membrane vesicle docking vesicle fusion vesicle-mediated transport | cytosol; early endosome; endomembrane system; endosome; late endosome; late endosome membrane; lysosomal membrane; perinuclear region of cytoplasm; phagocytic vesicle; recycling endosome; SNARE complex; trans-Golgi network; vesicle | chloride channel inhibitor activity SNAP receptor activity SNARE binding syntaxin binding ubiquitin protein ligase binding | Mus musculus | Coiled coil Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport Ubl conjugation | MAPDPWFSTY | MAPDPWFSTYDSTCQIAQEIAEKIQERNQCERRGEKTPKLTLTIRTLLKNLKVKIDLLKDLLLRAVSTRQITQLEGDRRQNLLDDLVTRERLLLASFKNEGAEPDLIRSSLMSEEAKRGTPNPWLCEEPEETRGLGFDEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEKLRTEARRVTLVDRKSTSCGMIMVILLLLVAIVVVAVWPTN | cellular response to type II interferon early endosome to late endosome transport endosome to lysosome transport intracellular protein transport regulation of protein localization to plasma membrane vesicle docking vesicle fusion vesicle-mediated transport cytosol; early endosome; endomembrane system; endosome; late endosome; late endosome membrane; lysosomal membrane; perinuclear region of cytoplasm; phagocytic vesicle; recycling endosome; SNARE complex; trans-Golgi network; vesicle chloride channel inhibitor activity SNAP receptor activity SNARE binding syntaxin binding ubiquitin protein ligase binding Mus musculus Coiled coil Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport Ubl conjugation MAPDPWFSTY MAPDPWFSTYDSTCQIAQEIAEKIQERNQCERRGEKTPKLTLTIRTLLKNLKVKIDLLKDLLLRAVSTRQITQLEGDRRQNLLDDLVTRERLLLASFKNEGAEPDLIRSSLMSEEAKRGTPNPWLCEEPEETRGLGFDEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEKLRTEARRVTLVDRKSTSCGMIMVILLLLVAIVVVAVWPTN |
mRNA export from nucleus poly(A)+ mRNA export from nucleus protein transport RNA export from nucleus | cytoplasm; cytoplasmic stress granule; nuclear inclusion body; nuclear pore; nuclear RNA export factor complex; nuclear speck; nucleus; transcription export complex | mRNA binding RNA binding | Rattus norvegicus | Acetylation Cytoplasm Leucine-rich repeat Methylation mRNA transport Nitration Nuclear pore complex Nucleus Protein transport Reference proteome Repeat RNA-binding Translocation Transport | MADEGKSYNE | MADEGKSYNEHDDRVSFPQRRKKGRGPFRWKCGVGNRRSGRGGSGIRSSRFEEDDGDVAMNDPQDGPRVRFNPYTTRPNRRRDTWHDRDRIHVTVRRDRAPQERGGAGTSQDGTTKNWFKITIPYGKKYDKMWLLSMIQSKCSVPFNPIEFHYENTRAHFFVENATTASALKAVNYKIQDRENGRISIIINSSAPPYIVQNELKPEQVEQLKLIMSKRYDGSQQALDLKGLRSDPDLVAQNIDVVLNRRGCMAAALRIIEENIPELLSLNLSNNRLYKLDDMSSIVQKAPNLKILNLSGNELKSEWELDKIKGLKLEELWLDRNPMCDTFLDQSTYISTIRERFPKLLRLDGHELPPPIAFDVEAPTMLPPCKGSYFGTENLKSLVLHFLQQYYAIYDSGDRQGLLDAYHDGACCSLSTPSNPQNPVRHNLAKYFNDSRNVKKIKDTTTRFRLLKHTRLNVVAFLNELPKTHHDVNSFVVDISAQTSTLLCFSVNGVFKEVDGKSRDSLRAFTRTFIAVPASNSGLCIVNDELFVRNASPEEIQRAFAMPAPTPSSSPVPTLSQEQQDMLQAFSTQSGMNLEWSQKCLQDNNWDYTRSAQAFTHLKAKGEIPEVAFMK | mRNA export from nucleus poly(A)+ mRNA export from nucleus protein transport RNA export from nucleus cytoplasm; cytoplasmic stress granule; nuclear inclusion body; nuclear pore; nuclear RNA export factor complex; nuclear speck; nucleus; transcription export complex mRNA binding RNA binding Rattus norvegicus Acetylation Cytoplasm Leucine-rich repeat Methylation mRNA transport Nitration Nuclear pore complex Nucleus Protein transport Reference proteome Repeat RNA-binding Translocation Transport MADEGKSYNE MADEGKSYNEHDDRVSFPQRRKKGRGPFRWKCGVGNRRSGRGGSGIRSSRFEEDDGDVAMNDPQDGPRVRFNPYTTRPNRRRDTWHDRDRIHVTVRRDRAPQERGGAGTSQDGTTKNWFKITIPYGKKYDKMWLLSMIQSKCSVPFNPIEFHYENTRAHFFVENATTASALKAVNYKIQDRENGRISIIINSSAPPYIVQNELKPEQVEQLKLIMSKRYDGSQQALDLKGLRSDPDLVAQNIDVVLNRRGCMAAALRIIEENIPELLSLNLSNNRLYKLDDMSSIVQKAPNLKILNLSGNELKSEWELDKIKGLKLEELWLDRNPMCDTFLDQSTYISTIRERFPKLLRLDGHELPPPIAFDVEAPTMLPPCKGSYFGTENLKSLVLHFLQQYYAIYDSGDRQGLLDAYHDGACCSLSTPSNPQNPVRHNLAKYFNDSRNVKKIKDTTTRFRLLKHTRLNVVAFLNELPKTHHDVNSFVVDISAQTSTLLCFSVNGVFKEVDGKSRDSLRAFTRTFIAVPASNSGLCIVNDELFVRNASPEEIQRAFAMPAPTPSSSPVPTLSQEQQDMLQAFSTQSGMNLEWSQKCLQDNNWDYTRSAQAFTHLKAKGEIPEVAFMK |
blastocyst hatching protein localization transmembrane receptor protein serine/threonine kinase signaling pathway | acrosomal vesicle; cytoplasm; motile cilium; sperm fibrous sheath; sperm midpiece; sperm principal piece | protein kinase A binding | Mus musculus | Cytoplasmic vesicle Phosphoprotein Reference proteome | MADRVDWLQS | MADRVDWLQSQSGVCKVGVYSPGDNQHQDWKMDTSTDPVRVLSWLRKDLEKSTAGFQDSRFKPGESSFVEEVAYPVDQRKGFCVDYYNTTNKGSPGRLHFEMSHKENPSQGLISHVGNGGSIDEVSFYANRLTNLVIAMARKEINEKIHGAENKCVHQSLYMGDEPTPHKSLSTVASELVNETVTACSKNISSDKAPGSGDRASGSSQAPGLRYTSTLKIKESTKEGKCPDDKPGTKKSFFYKEVFESRNAGDAKEGGRSLPGDQKLFRTSPDNRPDDFSNSISQGIMTYANSVVSDMMVSIMKTLKIQVKDTTIATILLKKVLMKHAKEVVSDLIDSFMKNLHGVTGSLMTDTDFVSAVKRSFFSHGSQKATDIMDAMLGKLYNVMFAKKFPENIRRARDKSESYSLISTKSRAGDPKLSNLNFAMKSESKLKENLFSTCKLEKEKTCAETLGEHIIKEGLHMWHKSQQKSPGLERAAKLGNAPQEVSFECPDPCEANPPHQPQPPENFANFMCDSDSWAKDLIVSALLLIQYHLAQGGKMDAQSFLEAAASTNFPTNKPPPPSPVVQDECKLKSPPHKICDQEQTEKKDLMSVIFNFIRNLLSETIFKSSRNCESNVHEQNTQEEEIHPCERPKTPCERPITPPAPKFCEDEEATGGALSGLTKMVANQLDNCMNGQMVEHLMDSVMKLCLIIAKSCDSPLSELGEEKCGDASRPNSAFPDNLYECLPVKGTGTAEALLQNAYLTIHNELRGLSGQPPEGCEIPKVIVSNHNLADTVQNKQLQAVLQWVAASELNVPILYFAGDDEGIQEKLLQLSATAVEKGRSVGEVLQSVLRYEKERQLDEAVGNVTRLQLLDWLMANL | blastocyst hatching protein localization transmembrane receptor protein serine/threonine kinase signaling pathway acrosomal vesicle; cytoplasm; motile cilium; sperm fibrous sheath; sperm midpiece; sperm principal piece protein kinase A binding Mus musculus Cytoplasmic vesicle Phosphoprotein Reference proteome MADRVDWLQS MADRVDWLQSQSGVCKVGVYSPGDNQHQDWKMDTSTDPVRVLSWLRKDLEKSTAGFQDSRFKPGESSFVEEVAYPVDQRKGFCVDYYNTTNKGSPGRLHFEMSHKENPSQGLISHVGNGGSIDEVSFYANRLTNLVIAMARKEINEKIHGAENKCVHQSLYMGDEPTPHKSLSTVASELVNETVTACSKNISSDKAPGSGDRASGSSQAPGLRYTSTLKIKESTKEGKCPDDKPGTKKSFFYKEVFESRNAGDAKEGGRSLPGDQKLFRTSPDNRPDDFSNSISQGIMTYANSVVSDMMVSIMKTLKIQVKDTTIATILLKKVLMKHAKEVVSDLIDSFMKNLHGVTGSLMTDTDFVSAVKRSFFSHGSQKATDIMDAMLGKLYNVMFAKKFPENIRRARDKSESYSLISTKSRAGDPKLSNLNFAMKSESKLKENLFSTCKLEKEKTCAETLGEHIIKEGLHMWHKSQQKSPGLERAAKLGNAPQEVSFECPDPCEANPPHQPQPPENFANFMCDSDSWAKDLIVSALLLIQYHLAQGGKMDAQSFLEAAASTNFPTNKPPPPSPVVQDECKLKSPPHKICDQEQTEKKDLMSVIFNFIRNLLSETIFKSSRNCESNVHEQNTQEEEIHPCERPKTPCERPITPPAPKFCEDEEATGGALSGLTKMVANQLDNCMNGQMVEHLMDSVMKLCLIIAKSCDSPLSELGEEKCGDASRPNSAFPDNLYECLPVKGTGTAEALLQNAYLTIHNELRGLSGQPPEGCEIPKVIVSNHNLADTVQNKQLQAVLQWVAASELNVPILYFAGDDEGIQEKLLQLSATAVEKGRSVGEVLQSVLRYEKERQLDEAVGNVTRLQLLDWLMANL |
malate metabolic process NAD metabolic process NADH metabolic process NADP metabolic process oxaloacetate metabolic process tricarboxylic acid cycle | cytoplasm; cytosol | hydroxyphenylpyruvate reductase activity L-malate dehydrogenase activity malate dehydrogenase activity NAD binding | Rattus norvegicus | Acetylation Cytoplasm Direct protein sequencing Methylation NAD Oxidoreductase Phosphoprotein Reference proteome Tricarboxylic acid cycle Ubl conjugation | MSEPIRVLVT | MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDCALPLLQDVIATDKEEVAFKDLDVAVLVGSMPRREGMERKDLLKANVKIFKSQGAALEKYAKKSVKVIVVGNPANTNCLTASKSAPSIPKENFSCLTRLDHNRAKSQIALKLGVTADDVKNVIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGEFITTVQQRGAAVIKARKLSSAMSAAKAISDHIRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVIKNKTWKFVEGLPINDFSREKMDLTAKELTEEKETAFEFLSSA | malate metabolic process NAD metabolic process NADH metabolic process NADP metabolic process oxaloacetate metabolic process tricarboxylic acid cycle cytoplasm; cytosol hydroxyphenylpyruvate reductase activity L-malate dehydrogenase activity malate dehydrogenase activity NAD binding Rattus norvegicus Acetylation Cytoplasm Direct protein sequencing Methylation NAD Oxidoreductase Phosphoprotein Reference proteome Tricarboxylic acid cycle Ubl conjugation MSEPIRVLVT MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDCALPLLQDVIATDKEEVAFKDLDVAVLVGSMPRREGMERKDLLKANVKIFKSQGAALEKYAKKSVKVIVVGNPANTNCLTASKSAPSIPKENFSCLTRLDHNRAKSQIALKLGVTADDVKNVIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGEFITTVQQRGAAVIKARKLSSAMSAAKAISDHIRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVIKNKTWKFVEGLPINDFSREKMDLTAKELTEEKETAFEFLSSA |
actin cytoskeleton organization bone morphogenesis focal adhesion assembly muscle cell development muscle contraction negative regulation of calcineurin-NFAT signaling cascade negative regulation of cold-induced thermogenesis negative regulation of glycolytic process negative regulation of oxidative phosphorylation negative regulation of relaxation of muscle positive regulation of bone mineralization involved in bone maturation positive regulation of fast-twitch skeletal muscle fiber contraction positive regulation of glucose catabolic process to lactate via pyruvate positive regulation of skeletal muscle fiber development positive regulation of skeletal muscle tissue growth regulation of aerobic respiration regulation of muscle system process regulation of the force of skeletal muscle contraction response to denervation involved in regulation of muscle adaptation skeletal muscle atrophy transition between fast and slow fiber | brush border; cell junction; cell projection; cortical actin cytoskeleton; focal adhesion; plasma membrane; sarcomere; striated muscle thin filament; Z disc | actin filament binding calcium ion binding identical protein binding protein-macromolecule adaptor activity transmembrane transporter binding | Mus musculus | Acetylation Actin-binding Calcium Metal-binding Reference proteome Repeat | MMMVMQPEGL | MMMVMQPEGLGAGEGPFSGGGGGEYMEQEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPRPDKGKMRFHKIANVNKALDFIASKGVKLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNVQNFHTSWKDGLALCALIHRHRPDLIDYAKLRKDDPIGNLNTAFEVAEKYLDIPKMLDAEDIVNTPKPDEKAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENEKLMEEYEKLASELLEWIRRTVPWLENRVGEPSMSAMQRKLEDFRDYRRLHKPPRVQEKCQLEINFNTLQTKLRLSHRPAFMPSEGKLVSDIANAWRGLEQVEKGYEDWLLSEIRRLQRLQHLAEKFQQKASLHEAWTRGKEEMLNQHDYESASLQEVRALLRRHEAFESDLAAHQDRVEHIAALAQELNELDYHEAASVNSRCQAICDQWDNLGTLTQKRRDALERMEKLLETIDQLQLEFARRAAPFNNWLDGAIEDLQDVWLVHSVEETQSLLTAHEQFKATLPEADRERGAILGIQGEIQKICQTYGLRPKSGNPYITLSSQDINNKWDTVRKLVPSRDQTLQEELARQQVNERLRRQFAAQANAIGPWIQGKVEEVGRLAAGLAGSLEEQMAGLRQQEQNIINYKSNIDRLEGDHQLLQESLVFDNKHTVYSMEHIRVGWEQLLTSIARTINEVENQVLTRDAKGLSQEQLNEFRASFNHFDRKRNGMMEPDDFRACLISMGYDLGEVEFARIMTMVDPNAAGVVTFQAFIDFMTRETAETDTAEQVVASFKILAGDKNYITPEELRRELPAEQAEYCIRRMAPYKGSGAPSGALDYVAFSSALYGESDL | actin cytoskeleton organization bone morphogenesis focal adhesion assembly muscle cell development muscle contraction negative regulation of calcineurin-NFAT signaling cascade negative regulation of cold-induced thermogenesis negative regulation of glycolytic process negative regulation of oxidative phosphorylation negative regulation of relaxation of muscle positive regulation of bone mineralization involved in bone maturation positive regulation of fast-twitch skeletal muscle fiber contraction positive regulation of glucose catabolic process to lactate via pyruvate positive regulation of skeletal muscle fiber development positive regulation of skeletal muscle tissue growth regulation of aerobic respiration regulation of muscle system process regulation of the force of skeletal muscle contraction response to denervation involved in regulation of muscle adaptation skeletal muscle atrophy transition between fast and slow fiber brush border; cell junction; cell projection; cortical actin cytoskeleton; focal adhesion; plasma membrane; sarcomere; striated muscle thin filament; Z disc actin filament binding calcium ion binding identical protein binding protein-macromolecule adaptor activity transmembrane transporter binding Mus musculus Acetylation Actin-binding Calcium Metal-binding Reference proteome Repeat MMMVMQPEGL MMMVMQPEGLGAGEGPFSGGGGGEYMEQEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPRPDKGKMRFHKIANVNKALDFIASKGVKLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNVQNFHTSWKDGLALCALIHRHRPDLIDYAKLRKDDPIGNLNTAFEVAEKYLDIPKMLDAEDIVNTPKPDEKAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENEKLMEEYEKLASELLEWIRRTVPWLENRVGEPSMSAMQRKLEDFRDYRRLHKPPRVQEKCQLEINFNTLQTKLRLSHRPAFMPSEGKLVSDIANAWRGLEQVEKGYEDWLLSEIRRLQRLQHLAEKFQQKASLHEAWTRGKEEMLNQHDYESASLQEVRALLRRHEAFESDLAAHQDRVEHIAALAQELNELDYHEAASVNSRCQAICDQWDNLGTLTQKRRDALERMEKLLETIDQLQLEFARRAAPFNNWLDGAIEDLQDVWLVHSVEETQSLLTAHEQFKATLPEADRERGAILGIQGEIQKICQTYGLRPKSGNPYITLSSQDINNKWDTVRKLVPSRDQTLQEELARQQVNERLRRQFAAQANAIGPWIQGKVEEVGRLAAGLAGSLEEQMAGLRQQEQNIINYKSNIDRLEGDHQLLQESLVFDNKHTVYSMEHIRVGWEQLLTSIARTINEVENQVLTRDAKGLSQEQLNEFRASFNHFDRKRNGMMEPDDFRACLISMGYDLGEVEFARIMTMVDPNAAGVVTFQAFIDFMTRETAETDTAEQVVASFKILAGDKNYITPEELRRELPAEQAEYCIRRMAPYKGSGAPSGALDYVAFSSALYGESDL |
maintenance of synapse structure motor learning neuron remodeling regulation of synapse pruning | cerebellar climbing fiber to Purkinje cell synapse; climbing fiber; collagen trimer; cytoplasm; presynapse; synaptic cleft | signaling receptor binding | Mus musculus | 3D-structure Collagen Reference proteome Secreted Signal | MLLVLVVLIP | MLLVLVVLIPVLVSSGGPDGHYEMLGTCRMVCDPYPARGPGAGARSDGGDALSEQSGAPPPSTLVQGPQGKPGRTGKPGPPGPPGDRGPPGPVGPPGEKGEPGKPGPPGLPGSGGSGAISTATYTTVPRVAFYAGLKNPHEGYEVLKFDDVVTNLGNNYDAASGKFTCNIPGTYFFTYHVLMRGGDGTSMWADLCKNGQVRASAIAQDADQNYDYASNSVILHLDAGDEVFIKLDGGKAHGGNSNKYSTFSGFIIYSD | maintenance of synapse structure motor learning neuron remodeling regulation of synapse pruning cerebellar climbing fiber to Purkinje cell synapse; climbing fiber; collagen trimer; cytoplasm; presynapse; synaptic cleft signaling receptor binding Mus musculus 3D-structure Collagen Reference proteome Secreted Signal MLLVLVVLIP MLLVLVVLIPVLVSSGGPDGHYEMLGTCRMVCDPYPARGPGAGARSDGGDALSEQSGAPPPSTLVQGPQGKPGRTGKPGPPGPPGDRGPPGPVGPPGEKGEPGKPGPPGLPGSGGSGAISTATYTTVPRVAFYAGLKNPHEGYEVLKFDDVVTNLGNNYDAASGKFTCNIPGTYFFTYHVLMRGGDGTSMWADLCKNGQVRASAIAQDADQNYDYASNSVILHLDAGDEVFIKLDGGKAHGGNSNKYSTFSGFIIYSD |
cellular response to leukemia inhibitory factor cobalamin metabolic process cobalamin transport fatty acid beta-oxidation long-chain fatty acid import into peroxisome peroxisome organization very long-chain fatty acid catabolic process | endoplasmic reticulum membrane; lysosomal membrane; peroxisomal membrane | ABC-type vitamin B12 transporter activity ATP binding ATP hydrolysis activity ATPase-coupled transmembrane transporter activity identical protein binding long-chain fatty acid transporter activity | Mus musculus | ATP-binding Endoplasmic reticulum Lysosome Membrane Nucleotide-binding Reference proteome Translocase Transmembrane Transmembrane helix Transport | MAVPGPTARA | MAVPGPTARAGARPRLDLQLVQRFVRIQKVFFPSWSSQNVLMFMTLLCVTLLEQLVIYQVGLIPSQYYGVLGNKDLDGFKALTLLAVTLIVLNSTLKSFDQFTCNLLYVSWRKDLTEHLHHLYFRARVYYTLNVLRDDIDNPDQRISQDVERFCRQLSSVTSKLIISPFTLTYYTYQCFQSTGWLGPVSIFGYFIVGTMVNKTLMGPIVTKLVQQEKLEGDFRFKHMQIRVNAEPAAFYRAGLVEHMRTDRRLQRLLQTQRELMSRELWLYIGINTFDYLGSILSYVVIAIPIFSGVYGDLSPTELSTLVSKNAFVCIYLISCFTQLIDLSTTLSDVAGYTHRIGELQEALLDMSRKSQDCEALGESEWDLDKTPGCPTTEPSDTAFLLDRVSILAPSSDKPLIKDLSLKICEGQSLLITGNTGTGKTSLLRVLGGLWEGMKGSVQMLADFGPHGVLFLPQKPFFTDGTLREQVIYPLKEIYPDSGSADDERIVRFLELAGLSSLVARTGGLDQQVDWNWYDVLSPGEMQRLSFARLFYLQPKYAVLDEATSALTEEAESELYRIGQQLGMTFISVGHRPSLEKFHSWVLRLHGGGSWELTRIKLE | cellular response to leukemia inhibitory factor cobalamin metabolic process cobalamin transport fatty acid beta-oxidation long-chain fatty acid import into peroxisome peroxisome organization very long-chain fatty acid catabolic process endoplasmic reticulum membrane; lysosomal membrane; peroxisomal membrane ABC-type vitamin B12 transporter activity ATP binding ATP hydrolysis activity ATPase-coupled transmembrane transporter activity identical protein binding long-chain fatty acid transporter activity Mus musculus ATP-binding Endoplasmic reticulum Lysosome Membrane Nucleotide-binding Reference proteome Translocase Transmembrane Transmembrane helix Transport MAVPGPTARA MAVPGPTARAGARPRLDLQLVQRFVRIQKVFFPSWSSQNVLMFMTLLCVTLLEQLVIYQVGLIPSQYYGVLGNKDLDGFKALTLLAVTLIVLNSTLKSFDQFTCNLLYVSWRKDLTEHLHHLYFRARVYYTLNVLRDDIDNPDQRISQDVERFCRQLSSVTSKLIISPFTLTYYTYQCFQSTGWLGPVSIFGYFIVGTMVNKTLMGPIVTKLVQQEKLEGDFRFKHMQIRVNAEPAAFYRAGLVEHMRTDRRLQRLLQTQRELMSRELWLYIGINTFDYLGSILSYVVIAIPIFSGVYGDLSPTELSTLVSKNAFVCIYLISCFTQLIDLSTTLSDVAGYTHRIGELQEALLDMSRKSQDCEALGESEWDLDKTPGCPTTEPSDTAFLLDRVSILAPSSDKPLIKDLSLKICEGQSLLITGNTGTGKTSLLRVLGGLWEGMKGSVQMLADFGPHGVLFLPQKPFFTDGTLREQVIYPLKEIYPDSGSADDERIVRFLELAGLSSLVARTGGLDQQVDWNWYDVLSPGEMQRLSFARLFYLQPKYAVLDEATSALTEEAESELYRIGQQLGMTFISVGHRPSLEKFHSWVLRLHGGGSWELTRIKLE |
antigen processing and presentation of exogenous peptide antigen via MHC class II associative learning cellular response to amyloid-beta cellular response to calcium ion cellular response to hepatocyte growth factor stimulus dendritic spine organization memory negative regulation of ERBB signaling pathway negative regulation of gene expression negative regulation of multicellular organism growth negative regulation of neuron apoptotic process positive regulation of cell population proliferation positive regulation of endothelial cell chemotaxis positive regulation of long-term synaptic potentiation positive regulation of mitotic cell cycle positive regulation of monocyte chemotaxis protein maturation proteolysis proteolysis involved in protein catabolic process receptor catabolic process renal system process response to acidic pH self proteolysis vacuolar protein processing | apical part of cell; cytoplasm; extracellular region; late endosome; lysosomal lumen; lysosome; perinuclear region of cytoplasm | cysteine-type endopeptidase activity endopeptidase activator activity peptidase activity | Mus musculus | 3D-structure Disulfide bond Glycoprotein Hydrolase Lysosome Protease Reference proteome Signal Thiol protease Zymogen | MTWRVAVLLS | MTWRVAVLLSLVLGAGAVPVGVDDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIIVMMYDDIANSEENPTPGVVINRPNGTDVYKGVLKDYTGEDVTPENFLAVLRGDAEAVKGKGSGKVLKSGPRDHVFIYFTDHGATGILVFPNDDLHVKDLNKTIRYMYEHKMYQKMVFYIEACESGSMMNHLPDDINVYATTAANPKESSYACYYDEERGTYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSHTNTSHVMQYGNKSISTMKVMQFQGMKHRASSPISLPPVTHLDLTPSPDVPLTILKRKLLRTNDVKESQNLIGQIQQFLDARHVIEKSVHKIVSLLAGFGETAERHLSERTMLTAHDCYQEAVTHFRTHCFNWHSVTYEHALRYLYVLANLCEAPYPIDRIEMAMDKVCLSHY | antigen processing and presentation of exogenous peptide antigen via MHC class II associative learning cellular response to amyloid-beta cellular response to calcium ion cellular response to hepatocyte growth factor stimulus dendritic spine organization memory negative regulation of ERBB signaling pathway negative regulation of gene expression negative regulation of multicellular organism growth negative regulation of neuron apoptotic process positive regulation of cell population proliferation positive regulation of endothelial cell chemotaxis positive regulation of long-term synaptic potentiation positive regulation of mitotic cell cycle positive regulation of monocyte chemotaxis protein maturation proteolysis proteolysis involved in protein catabolic process receptor catabolic process renal system process response to acidic pH self proteolysis vacuolar protein processing apical part of cell; cytoplasm; extracellular region; late endosome; lysosomal lumen; lysosome; perinuclear region of cytoplasm cysteine-type endopeptidase activity endopeptidase activator activity peptidase activity Mus musculus 3D-structure Disulfide bond Glycoprotein Hydrolase Lysosome Protease Reference proteome Signal Thiol protease Zymogen MTWRVAVLLS MTWRVAVLLSLVLGAGAVPVGVDDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIIVMMYDDIANSEENPTPGVVINRPNGTDVYKGVLKDYTGEDVTPENFLAVLRGDAEAVKGKGSGKVLKSGPRDHVFIYFTDHGATGILVFPNDDLHVKDLNKTIRYMYEHKMYQKMVFYIEACESGSMMNHLPDDINVYATTAANPKESSYACYYDEERGTYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSHTNTSHVMQYGNKSISTMKVMQFQGMKHRASSPISLPPVTHLDLTPSPDVPLTILKRKLLRTNDVKESQNLIGQIQQFLDARHVIEKSVHKIVSLLAGFGETAERHLSERTMLTAHDCYQEAVTHFRTHCFNWHSVTYEHALRYLYVLANLCEAPYPIDRIEMAMDKVCLSHY |
protein stabilization protein transport within extracellular region vitamin transport | cytoplasm; extracellular space | vitamin E binding | Mus musculus | Alternative splicing Disulfide bond Glycoprotein Protein transport Reference proteome Repeat Secreted Signal Transport | MRHLKLTGFI | MRHLKLTGFIFFLLPLTESLALPTKPQDVDHFNATQKFIDENTTYLAIIAFSQYVQEASFDEVETLVKVMLDYRDRCWADNTLPECSKTANDAIQDMLCDMEGLPQKHNFSHCCGKAGFPRRLCFFYNKKANVGFLPPFPTLDPEEKCQAYKNNSESFLHLYMYEVARRNPFVFAPVLLAVAAWFEEAATTCCEQQQKATCFQAKAAPITQYLKASSSYQRNVCGALIKFGPKVLNSINVAVFSKKFPKIGFKDLTTLLEDVSSMYEGCCEGDVVHCIRSQSQVVNHICSKQDSISSKIKVCCEKKTLEREACIINANKDDRPEGLSLREAKFTESENVCQERDSDPDKFFAEFIYEYSRRHPDLSTPELLRITKVYMDFLEDCCSRENPAGCYRHVEDKFNETTQRSLAMVQQECKQFQELGKDTLQRHFLVKFTKAAPQLPMEELVSLSKEMVAALTTCCTLSDEFACVDNLADLVLGELCGVNTNRTINPAVDHCCKTDFAFRRHCFEHLKADTTYELPSVSALVSALHTDWCQPRKEDLQNKKHRFLVNLVKWMPGITDEEWLCLFTKFTAAREECSEVQEPESCFSPESSKTGDESQATEKQR | protein stabilization protein transport within extracellular region vitamin transport cytoplasm; extracellular space vitamin E binding Mus musculus Alternative splicing Disulfide bond Glycoprotein Protein transport Reference proteome Repeat Secreted Signal Transport MRHLKLTGFI MRHLKLTGFIFFLLPLTESLALPTKPQDVDHFNATQKFIDENTTYLAIIAFSQYVQEASFDEVETLVKVMLDYRDRCWADNTLPECSKTANDAIQDMLCDMEGLPQKHNFSHCCGKAGFPRRLCFFYNKKANVGFLPPFPTLDPEEKCQAYKNNSESFLHLYMYEVARRNPFVFAPVLLAVAAWFEEAATTCCEQQQKATCFQAKAAPITQYLKASSSYQRNVCGALIKFGPKVLNSINVAVFSKKFPKIGFKDLTTLLEDVSSMYEGCCEGDVVHCIRSQSQVVNHICSKQDSISSKIKVCCEKKTLEREACIINANKDDRPEGLSLREAKFTESENVCQERDSDPDKFFAEFIYEYSRRHPDLSTPELLRITKVYMDFLEDCCSRENPAGCYRHVEDKFNETTQRSLAMVQQECKQFQELGKDTLQRHFLVKFTKAAPQLPMEELVSLSKEMVAALTTCCTLSDEFACVDNLADLVLGELCGVNTNRTINPAVDHCCKTDFAFRRHCFEHLKADTTYELPSVSALVSALHTDWCQPRKEDLQNKKHRFLVNLVKWMPGITDEEWLCLFTKFTAAREECSEVQEPESCFSPESSKTGDESQATEKQR |
bone resorption central nervous system development epithelial cell differentiation lysosomal protein catabolic process lysosome organization nervous system development neuromuscular process controlling balance peptide catabolic process protein catabolic process protein localization to chromosome, telomeric region proteolysis | Golgi apparatus; lysosome; melanosome; membrane raft; mitochondrion; recycling endosome | endopeptidase activity lysophosphatidic acid binding metal ion binding peptidase activity peptide binding serine-type endopeptidase activity serine-type peptidase activity sulfatide binding tripeptidyl-peptidase activity | Mus musculus | Autocatalytic cleavage Calcium Disulfide bond Glycoprotein Hydrolase Lysosome Metal-binding Protease Reference proteome Serine protease Signal Zymogen | MGLQARLLGL | MGLQARLLGLLALVIAGKCTYNPEPDQRWMLPPGWVSLGRVDPEEELSLTFALKQRNLERLSELVQAVSDPSSPQYGKYLTLEDVAELVQPSPLTLLTVQKWLSAAGARNCDSVTTQDFLTCWLSVRQAELLLPGAEFHRYVGGPTKTHVIRSPHPYQLPQALAPHVDFVGGLHRFPPSSPRQRPEPQQVGTVSLHLGVTPSVLRQRYNLTAKDVGSGTTNNSQACAQFLEQYFHNSDLTEFMRLFGGSFTHQASVAKVVGKQGRGRAGIEASLDVEYLMSAGANISTWVYSSPGRHEAQEPFLQWLLLLSNESSLPHVHTVSYGDDEDSLSSIYIQRVNTEFMKAAARGLTLLFASGDTGAGCWSVSGRHKFRPSFPASSPYVTTVGGTSFKNPFLITDEVVDYISGGGFSNVFPRPPYQEEAVAQFLKSSSHLPPSSYFNASGRAYPDVAALSDGYWVVSNMVPIPWVSGTSASTPVFGGILSLINEHRILNGRPPLGFLNPRLYQQHGTGLFDVTHGCHESCLNEEVEGQGFCSGPGWDPVTGWGTPNFPALLKTLLNP | bone resorption central nervous system development epithelial cell differentiation lysosomal protein catabolic process lysosome organization nervous system development neuromuscular process controlling balance peptide catabolic process protein catabolic process protein localization to chromosome, telomeric region proteolysis Golgi apparatus; lysosome; melanosome; membrane raft; mitochondrion; recycling endosome endopeptidase activity lysophosphatidic acid binding metal ion binding peptidase activity peptide binding serine-type endopeptidase activity serine-type peptidase activity sulfatide binding tripeptidyl-peptidase activity Mus musculus Autocatalytic cleavage Calcium Disulfide bond Glycoprotein Hydrolase Lysosome Metal-binding Protease Reference proteome Serine protease Signal Zymogen MGLQARLLGL MGLQARLLGLLALVIAGKCTYNPEPDQRWMLPPGWVSLGRVDPEEELSLTFALKQRNLERLSELVQAVSDPSSPQYGKYLTLEDVAELVQPSPLTLLTVQKWLSAAGARNCDSVTTQDFLTCWLSVRQAELLLPGAEFHRYVGGPTKTHVIRSPHPYQLPQALAPHVDFVGGLHRFPPSSPRQRPEPQQVGTVSLHLGVTPSVLRQRYNLTAKDVGSGTTNNSQACAQFLEQYFHNSDLTEFMRLFGGSFTHQASVAKVVGKQGRGRAGIEASLDVEYLMSAGANISTWVYSSPGRHEAQEPFLQWLLLLSNESSLPHVHTVSYGDDEDSLSSIYIQRVNTEFMKAAARGLTLLFASGDTGAGCWSVSGRHKFRPSFPASSPYVTTVGGTSFKNPFLITDEVVDYISGGGFSNVFPRPPYQEEAVAQFLKSSSHLPPSSYFNASGRAYPDVAALSDGYWVVSNMVPIPWVSGTSASTPVFGGILSLINEHRILNGRPPLGFLNPRLYQQHGTGLFDVTHGCHESCLNEEVEGQGFCSGPGWDPVTGWGTPNFPALLKTLLNP |
cell division DNA replication initiation mitotic DNA replication checkpoint signaling positive regulation of chromosome segregation positive regulation of cytokinesis positive regulation of fibroblast proliferation regulation of mitotic metaphase/anaphase transition | cytoplasm; cytosol; intercellular bridge; mitotic spindle; nucleoplasm; nucleus; spindle; spindle midzone; spindle pole | ATP binding ATP hydrolysis activity chromatin binding kinase binding | Mus musculus | ATP-binding Cell cycle Cell division Cytoplasm DNA replication Mitosis Nucleotide-binding Nucleus Phosphoprotein Reference proteome Ubl conjugation | MPQTRSQTQA | MPQTRSQTQATIGFPKKKLSNTLKKPNSRDCEVKLRNVQPVPTTPCVDVKLLPLSPRKRLGDDNLCNTPRLSPCSPPKLGKKENGPPRSHTWKGCRLVFDDEPTFKASPPKEQDRVRQHQIRSSSAQRSPESKADPEQKCPPEKESVCIRLFKQEGTCYQQAKLVLNTAVPDRLPAREQEMGVIRNFLKEHICGKKAGSLYLSGAPGTGKTACLSRILQDFKKEVKGFKSILLNCMSLRSAQAVFPAIAQEIGREELCRPAGKDLMRKLEKHLTAEKGPMIVLVLDEMDQLDSKGQDVLYTLFEWPWLSNSRLVLIGIANTLDLTDRILPRLEARENCKPQLLNFPPYTRNQIAAILQDRLSQVSKDQVLDSAAIQFCARKVSAVSGDIRKALDVCRRAIEIVESDVRSQTVLKPLSECKSPSESPVPKRVGLAHISQVISEVDGNRVTLSQENTQDSLPLQQKILVCSLLLLTRRLKIKEVTLGKLYEAYSSICRKQQVTAVDQSECLSLSGLLESRGLVGLKKNKESRLTKVSLKIEEKEIEHVLNGKAFTGNILAAGLP | cell division DNA replication initiation mitotic DNA replication checkpoint signaling positive regulation of chromosome segregation positive regulation of cytokinesis positive regulation of fibroblast proliferation regulation of mitotic metaphase/anaphase transition cytoplasm; cytosol; intercellular bridge; mitotic spindle; nucleoplasm; nucleus; spindle; spindle midzone; spindle pole ATP binding ATP hydrolysis activity chromatin binding kinase binding Mus musculus ATP-binding Cell cycle Cell division Cytoplasm DNA replication Mitosis Nucleotide-binding Nucleus Phosphoprotein Reference proteome Ubl conjugation MPQTRSQTQA MPQTRSQTQATIGFPKKKLSNTLKKPNSRDCEVKLRNVQPVPTTPCVDVKLLPLSPRKRLGDDNLCNTPRLSPCSPPKLGKKENGPPRSHTWKGCRLVFDDEPTFKASPPKEQDRVRQHQIRSSSAQRSPESKADPEQKCPPEKESVCIRLFKQEGTCYQQAKLVLNTAVPDRLPAREQEMGVIRNFLKEHICGKKAGSLYLSGAPGTGKTACLSRILQDFKKEVKGFKSILLNCMSLRSAQAVFPAIAQEIGREELCRPAGKDLMRKLEKHLTAEKGPMIVLVLDEMDQLDSKGQDVLYTLFEWPWLSNSRLVLIGIANTLDLTDRILPRLEARENCKPQLLNFPPYTRNQIAAILQDRLSQVSKDQVLDSAAIQFCARKVSAVSGDIRKALDVCRRAIEIVESDVRSQTVLKPLSECKSPSESPVPKRVGLAHISQVISEVDGNRVTLSQENTQDSLPLQQKILVCSLLLLTRRLKIKEVTLGKLYEAYSSICRKQQVTAVDQSECLSLSGLLESRGLVGLKKNKESRLTKVSLKIEEKEIEHVLNGKAFTGNILAAGLP |
glyceraldehyde-3-phosphate biosynthetic process lipid transport malate transmembrane transport malate transport oxaloacetate transport phosphate ion transmembrane transport phosphate ion transport succinate transmembrane transport succinate transport sulfate transport thiosulfate transport | mitochondrial inner membrane; mitochondrion; nucleoplasm | antiporter activity dicarboxylic acid transmembrane transporter activity malate transmembrane transporter activity oxaloacetate transmembrane transporter activity phosphate ion transmembrane transporter activity secondary active transmembrane transporter activity succinate transmembrane transporter activity sulfate transmembrane transporter activity thiosulfate transmembrane transporter activity | Rattus norvegicus | Acetylation Antiport Lipid transport Membrane Mitochondrion Mitochondrion inner membrane Reference proteome Repeat Transmembrane Transmembrane helix Transport | MAEARTSRWY | MAEARTSRWYFGGLASCGAACCTHPLDLLKVHLQTQQEVKLRMTGMALQVVRTDGFLALYNGLSASLCRQMTYSLTRFAIYETMRDYMTKDSQGPLPFYSKVLLGGISGLTGGFVGTPADLVNVRMQNDMKLPLSQRRNYSHALDGLYRVAREEGLKKLFSGATMASSRGALVTVGQLSCYDQAKQLVLSTGYLSDNIFTHFLSSFIAGGCATFLCQPLDVLKTRLMNSKGEYQGVFHCAVETAKLGPQAFFKGLVPAGVRLVPHTVLTFMFLEQLRKHFGIKVAT | glyceraldehyde-3-phosphate biosynthetic process lipid transport malate transmembrane transport malate transport oxaloacetate transport phosphate ion transmembrane transport phosphate ion transport succinate transmembrane transport succinate transport sulfate transport thiosulfate transport mitochondrial inner membrane; mitochondrion; nucleoplasm antiporter activity dicarboxylic acid transmembrane transporter activity malate transmembrane transporter activity oxaloacetate transmembrane transporter activity phosphate ion transmembrane transporter activity secondary active transmembrane transporter activity succinate transmembrane transporter activity sulfate transmembrane transporter activity thiosulfate transmembrane transporter activity Rattus norvegicus Acetylation Antiport Lipid transport Membrane Mitochondrion Mitochondrion inner membrane Reference proteome Repeat Transmembrane Transmembrane helix Transport MAEARTSRWY MAEARTSRWYFGGLASCGAACCTHPLDLLKVHLQTQQEVKLRMTGMALQVVRTDGFLALYNGLSASLCRQMTYSLTRFAIYETMRDYMTKDSQGPLPFYSKVLLGGISGLTGGFVGTPADLVNVRMQNDMKLPLSQRRNYSHALDGLYRVAREEGLKKLFSGATMASSRGALVTVGQLSCYDQAKQLVLSTGYLSDNIFTHFLSSFIAGGCATFLCQPLDVLKTRLMNSKGEYQGVFHCAVETAKLGPQAFFKGLVPAGVRLVPHTVLTFMFLEQLRKHFGIKVAT |
adult heart development apoptotic process cell differentiation chondrocyte differentiation endochondral ossification nervous system development osteoblast differentiation positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of vascular associated smooth muscle cell proliferation regulation of DNA-templated transcription skeletal muscle cell differentiation | cytoplasm; nucleus | DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor binding enzyme binding histone deacetylase binding protein heterodimerization activity protein homodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II-specific DNA-binding transcription factor binding sequence-specific double-stranded DNA binding | Rattus norvegicus | Acetylation Activator Apoptosis Developmental protein Differentiation DNA-binding Isopeptide bond Neurogenesis Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Ubl conjugation | MGRKKIQIQR | MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYASTDMDKVLLKYTEYNEPHESRTNADIIETLRKKGFNGCDSPEPDGEDSLEQSPLLEDKYRRASEELDGLFRRYGSSVPAPNFAMPVTVPVSNQSSMQFSNPSSSLVTPSLVTSSLTDPRLLSPQQPALQRNSVSPGLPQRPASAGAMLGRDLNSANGACPNPVGNGYVSARASPGLLPVANGNGLNKVIPAKSPPPPTHNTQLGAPSRKPDLRVITSQGGKGLMHHLNNAQRLGVSQSTHSLTTPVVSVATPSLLSQGLPFSSMPTAYNTDYQLPSAELSSLPAFSSPAGLALGNVTAWQQPQQPQQPQPPQPPQSQPQPPQPQPQQPPQQQPHLVPVSLSNLIPGSPLPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVFPAARPEPGEGLSSPAGGSYETGDRDDGRGDFGPTLGLLRPAPEPEAEGSAVKRMRLDTWTLK | adult heart development apoptotic process cell differentiation chondrocyte differentiation endochondral ossification nervous system development osteoblast differentiation positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of vascular associated smooth muscle cell proliferation regulation of DNA-templated transcription skeletal muscle cell differentiation cytoplasm; nucleus DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor binding enzyme binding histone deacetylase binding protein heterodimerization activity protein homodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II-specific DNA-binding transcription factor binding sequence-specific double-stranded DNA binding Rattus norvegicus Acetylation Activator Apoptosis Developmental protein Differentiation DNA-binding Isopeptide bond Neurogenesis Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Ubl conjugation MGRKKIQIQR MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYASTDMDKVLLKYTEYNEPHESRTNADIIETLRKKGFNGCDSPEPDGEDSLEQSPLLEDKYRRASEELDGLFRRYGSSVPAPNFAMPVTVPVSNQSSMQFSNPSSSLVTPSLVTSSLTDPRLLSPQQPALQRNSVSPGLPQRPASAGAMLGRDLNSANGACPNPVGNGYVSARASPGLLPVANGNGLNKVIPAKSPPPPTHNTQLGAPSRKPDLRVITSQGGKGLMHHLNNAQRLGVSQSTHSLTTPVVSVATPSLLSQGLPFSSMPTAYNTDYQLPSAELSSLPAFSSPAGLALGNVTAWQQPQQPQQPQPPQPPQSQPQPPQPQPQQPPQQQPHLVPVSLSNLIPGSPLPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVFPAARPEPGEGLSSPAGGSYETGDRDDGRGDFGPTLGLLRPAPEPEAEGSAVKRMRLDTWTLK |
angiogenesis calcium-mediated signaling cell adhesion cell chemotaxis chemokine-mediated signaling pathway immune response negative regulation of cell population proliferation negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage oculomotor nerve development positive regulation of cytosolic calcium ion concentration positive regulation of ERK1 and ERK2 cascade positive regulation of mesenchymal stem cell migration receptor internalization vasculogenesis | cell surface; clathrin-coated pit; early endosome; endosome; external side of plasma membrane; plasma membrane; recycling endosome | C-C chemokine binding C-C chemokine receptor activity C-X-C chemokine binding C-X-C chemokine receptor activity coreceptor activity scavenger receptor activity | Rattus norvegicus | Cell adhesion Cell membrane Developmental protein Disulfide bond Endosome G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix Ubl conjugation | MDVHLFDYVE | MDVHLFDYVEPGNYSDINWPCNSSDCIVVDTVQCPAMPNKNVLLYTLSFIYIFIFVIGMIANSVVVWVNIQAKTTGYDTHCYILNLAIADLWVVITIPVWVVSLVQHNQWPMGELTCKITHLIFSINLFGSIFFLACMSVDRYLSITYFTSTSSYKKKMVRRVVCVLVWLLAFFVSLPDTYYLKTVTSASNNETYCRSFYPEHSIKEWLIGMELVSVILGFAVPFTIIAIFYFLLARAMSASGDQEKHSSRKIIFSYVVVFLVCWLPYHFVVLLDIFSILHYIPFTCQLENVLFTALHVTQCLSLVHCCVNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEYSALEQNTK | angiogenesis calcium-mediated signaling cell adhesion cell chemotaxis chemokine-mediated signaling pathway immune response negative regulation of cell population proliferation negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage oculomotor nerve development positive regulation of cytosolic calcium ion concentration positive regulation of ERK1 and ERK2 cascade positive regulation of mesenchymal stem cell migration receptor internalization vasculogenesis cell surface; clathrin-coated pit; early endosome; endosome; external side of plasma membrane; plasma membrane; recycling endosome C-C chemokine binding C-C chemokine receptor activity C-X-C chemokine binding C-X-C chemokine receptor activity coreceptor activity scavenger receptor activity Rattus norvegicus Cell adhesion Cell membrane Developmental protein Disulfide bond Endosome G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix Ubl conjugation MDVHLFDYVE MDVHLFDYVEPGNYSDINWPCNSSDCIVVDTVQCPAMPNKNVLLYTLSFIYIFIFVIGMIANSVVVWVNIQAKTTGYDTHCYILNLAIADLWVVITIPVWVVSLVQHNQWPMGELTCKITHLIFSINLFGSIFFLACMSVDRYLSITYFTSTSSYKKKMVRRVVCVLVWLLAFFVSLPDTYYLKTVTSASNNETYCRSFYPEHSIKEWLIGMELVSVILGFAVPFTIIAIFYFLLARAMSASGDQEKHSSRKIIFSYVVVFLVCWLPYHFVVLLDIFSILHYIPFTCQLENVLFTALHVTQCLSLVHCCVNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEYSALEQNTK |
actin cytoskeleton organization actin filament branching actin filament bundle assembly actin filament organization cell migration cellular response to platelet-derived growth factor stimulus endothelial cell chemotaxis negative regulation of Arp2/3 complex-mediated actin nucleation negative regulation of lamellipodium morphogenesis negative regulation of smooth muscle cell chemotaxis positive regulation of lamellipodium morphogenesis protein kinase C signaling protein localization to cell leading edge regulation of Arp2/3 complex-mediated actin nucleation ruffle organization wound healing | actin filament; cell leading edge; cell periphery; cytoplasm; cytosol; lamellipodium; perinuclear region of cytoplasm; plasma membrane; stress fiber | actin filament binding Arp2/3 complex binding cytoskeletal protein binding identical protein binding protein-containing complex binding | Rattus norvegicus | Actin-binding Coiled coil Cytoplasm Cytoskeleton Phosphoprotein Reference proteome Repeat WD repeat | MSFRKVVRQS | MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFMVLPLNKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIITWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCTACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTAGFSRMSERQLALWDPENFEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITDEPPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDLYPDTAGPDAALEAEDWVSGQDADPILISLREAYVPSKQRDLKVSRRNVLSDSKPAGYSRSGVSTATAITDIPSGNLAGSGEAGKLEEVMHGLRALRVLVKEQGERISRLEEHLGRMENGDT | actin cytoskeleton organization actin filament branching actin filament bundle assembly actin filament organization cell migration cellular response to platelet-derived growth factor stimulus endothelial cell chemotaxis negative regulation of Arp2/3 complex-mediated actin nucleation negative regulation of lamellipodium morphogenesis negative regulation of smooth muscle cell chemotaxis positive regulation of lamellipodium morphogenesis protein kinase C signaling protein localization to cell leading edge regulation of Arp2/3 complex-mediated actin nucleation ruffle organization wound healing actin filament; cell leading edge; cell periphery; cytoplasm; cytosol; lamellipodium; perinuclear region of cytoplasm; plasma membrane; stress fiber actin filament binding Arp2/3 complex binding cytoskeletal protein binding identical protein binding protein-containing complex binding Rattus norvegicus Actin-binding Coiled coil Cytoplasm Cytoskeleton Phosphoprotein Reference proteome Repeat WD repeat MSFRKVVRQS MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFMVLPLNKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIITWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCTACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTAGFSRMSERQLALWDPENFEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITDEPPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDLYPDTAGPDAALEAEDWVSGQDADPILISLREAYVPSKQRDLKVSRRNVLSDSKPAGYSRSGVSTATAITDIPSGNLAGSGEAGKLEEVMHGLRALRVLVKEQGERISRLEEHLGRMENGDT |
benzene-containing compound metabolic process cell population proliferation cell redox homeostasis cellular response to copper ion cellular response to hyperoxia gastrulation halogen metabolic process hydrogen peroxide catabolic process mesoderm formation NADPH oxidation positive regulation of apoptotic process response to axon injury response to hyperoxia response to oxidative stress response to selenium ion response to xenobiotic stimulus selenocysteine metabolic process | cytoplasm; cytosol; mitochondrion; neuronal cell body; nucleus | FAD binding identical protein binding mercury ion binding NAD(P)H oxidase H2O2-forming activity NADPH peroxidase activity selenate reductase activity thioredoxin-disulfide reductase (NADP) activity | Rattus norvegicus | 3D-structure Cytoplasm Direct protein sequencing Disulfide bond FAD Flavoprotein NADP Oxidoreductase Phosphoprotein Redox-active center Reference proteome Selenocysteine Ubl conjugation | MNDSKDAPKS | MNDSKDAPKSYDFDLIIIGGGSGGLAAAKEAAKFDKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALKDSRNYGWKLEDTVKHDWEKMTESVQNHIGSLNWGYRVALREKKVVYENAYGKFIGPHKIMATNNKGKEKVYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPTKIEQIEAGTPGRLKVTAKSTNSEETIEDEFNTVLLAVGRDSCTRTIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGGSTVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTVPSRDNNKCYAKVICNLKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEIFTTLSVTKRSGGDILQSGCUG | benzene-containing compound metabolic process cell population proliferation cell redox homeostasis cellular response to copper ion cellular response to hyperoxia gastrulation halogen metabolic process hydrogen peroxide catabolic process mesoderm formation NADPH oxidation positive regulation of apoptotic process response to axon injury response to hyperoxia response to oxidative stress response to selenium ion response to xenobiotic stimulus selenocysteine metabolic process cytoplasm; cytosol; mitochondrion; neuronal cell body; nucleus FAD binding identical protein binding mercury ion binding NAD(P)H oxidase H2O2-forming activity NADPH peroxidase activity selenate reductase activity thioredoxin-disulfide reductase (NADP) activity Rattus norvegicus 3D-structure Cytoplasm Direct protein sequencing Disulfide bond FAD Flavoprotein NADP Oxidoreductase Phosphoprotein Redox-active center Reference proteome Selenocysteine Ubl conjugation MNDSKDAPKS MNDSKDAPKSYDFDLIIIGGGSGGLAAAKEAAKFDKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALKDSRNYGWKLEDTVKHDWEKMTESVQNHIGSLNWGYRVALREKKVVYENAYGKFIGPHKIMATNNKGKEKVYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPTKIEQIEAGTPGRLKVTAKSTNSEETIEDEFNTVLLAVGRDSCTRTIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGGSTVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTVPSRDNNKCYAKVICNLKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEIFTTLSVTKRSGGDILQSGCUG |
actin cytoskeleton organization cell-matrix adhesion regulation of cell shape regulation of receptor internalization | cell cortex; cytoplasm; cytosol; nucleoplasm; postsynapse; ruffle; ubiquitin ligase complex | identical protein binding protein homodimerization activity | Mus musculus | 3D-structure Acetylation Cell projection Cytoplasm Kelch repeat Nucleus Reference proteome Repeat Synapse | MAAGGAVAVA | MAAGGAVAVAPECRLLPYALHKWSSFSSTYLPENILVDKPNDQSSRWSSESNYPPQYLILKLERPAIVQNITFGKYEKTHVCNLKKFKVFGGMNEENMTELLSSGLKNDYNKETFTLKHKIDEQMFPCRFIKIVPLLSWGPSFNFSIWYVELSGIDDPDIVQPCLNWYSKYREQEAIRLCLKHFRQHNYTEAFESLQKKTKIALEHPMLTDMHDKLVLKGDFDACEELIEKAVNDGLFNQYISQQEYKPRWSQIIPKSTKGDGEDNRPGMRGGHQMVIDVQTETVYLFGGWDGTQDLADFWAYSVKENQWTCISRDTEKENGPSARSCHKMCIDIQRRQIYTLGRYLDSSVRNSKSLKSDFYRYDIDTNTWMLLSEDTAADGGPKLVFDHQMCMDSEKHMIYTFGGRILTCNGSVDDSRASEPQFSGLFAFNCQCQTWKLLREDSCNAGPEDIQSRIGHCMLFHSKNRCLYVFGGQRSKTYLNDFFSYDVDSDHVDIISDGTKKDSGMVPMTGFTQRATIDPELNEIHVLSGLSKDKEKREENVRNSFWIYDIVRNSWSCVYKNDQATKDNLSKSLQEEEPCPRFAHQLVYDELHKVHYLFGGNPGKSCSPKMRLDDFWSLKLCRPSKDYLLRHCKYLIRKHRFEEKAQMDPLSALKYLQNDLYITVDHSDPEETKEFQLLASALFKSGSDFTALGFSDVDHTYAQRTQLFDTLVNFFPDSMTPPKGNLVDLITL | actin cytoskeleton organization cell-matrix adhesion regulation of cell shape regulation of receptor internalization cell cortex; cytoplasm; cytosol; nucleoplasm; postsynapse; ruffle; ubiquitin ligase complex identical protein binding protein homodimerization activity Mus musculus 3D-structure Acetylation Cell projection Cytoplasm Kelch repeat Nucleus Reference proteome Repeat Synapse MAAGGAVAVA MAAGGAVAVAPECRLLPYALHKWSSFSSTYLPENILVDKPNDQSSRWSSESNYPPQYLILKLERPAIVQNITFGKYEKTHVCNLKKFKVFGGMNEENMTELLSSGLKNDYNKETFTLKHKIDEQMFPCRFIKIVPLLSWGPSFNFSIWYVELSGIDDPDIVQPCLNWYSKYREQEAIRLCLKHFRQHNYTEAFESLQKKTKIALEHPMLTDMHDKLVLKGDFDACEELIEKAVNDGLFNQYISQQEYKPRWSQIIPKSTKGDGEDNRPGMRGGHQMVIDVQTETVYLFGGWDGTQDLADFWAYSVKENQWTCISRDTEKENGPSARSCHKMCIDIQRRQIYTLGRYLDSSVRNSKSLKSDFYRYDIDTNTWMLLSEDTAADGGPKLVFDHQMCMDSEKHMIYTFGGRILTCNGSVDDSRASEPQFSGLFAFNCQCQTWKLLREDSCNAGPEDIQSRIGHCMLFHSKNRCLYVFGGQRSKTYLNDFFSYDVDSDHVDIISDGTKKDSGMVPMTGFTQRATIDPELNEIHVLSGLSKDKEKREENVRNSFWIYDIVRNSWSCVYKNDQATKDNLSKSLQEEEPCPRFAHQLVYDELHKVHYLFGGNPGKSCSPKMRLDDFWSLKLCRPSKDYLLRHCKYLIRKHRFEEKAQMDPLSALKYLQNDLYITVDHSDPEETKEFQLLASALFKSGSDFTALGFSDVDHTYAQRTQLFDTLVNFFPDSMTPPKGNLVDLITL |
negative regulation of amyloid precursor protein biosynthetic process | endosome membrane; extracellular space; Golgi apparatus; Golgi membrane; Golgi-associated vesicle membrane; intracellular membrane-bounded organelle; organelle membrane; plasma membrane | amyloid-beta binding ATP binding | Mus musculus | Cell membrane Disulfide bond Endosome Glycoprotein Golgi apparatus Membrane Reference proteome Secreted Signal-anchor Transmembrane Transmembrane helix | MVKVTFNSAL | MVKVTFNSALAQKEAKKDEPKSSEEALIVPPDAVAVDCKDPGDVVPVGQRRAWCWCMCFGLAFMLAGVILGGAYLYKYFALQPDDVYYCGLKYIKDDVILNEPSADAPAARYQTIEENIKIFEEDAVEFISVPVPEFADSDPANIVHDFNKKLTAYLDLNLDKCYVIPLNTSIVMPPKNLLELLINIKAGTYLPQSYLIHEHMVITDRIENVDNLGFFIYRLCHDKETYKLQRRETIRGIQKREASNCFTIRHFENKFAVETLICS | negative regulation of amyloid precursor protein biosynthetic process endosome membrane; extracellular space; Golgi apparatus; Golgi membrane; Golgi-associated vesicle membrane; intracellular membrane-bounded organelle; organelle membrane; plasma membrane amyloid-beta binding ATP binding Mus musculus Cell membrane Disulfide bond Endosome Glycoprotein Golgi apparatus Membrane Reference proteome Secreted Signal-anchor Transmembrane Transmembrane helix MVKVTFNSAL MVKVTFNSALAQKEAKKDEPKSSEEALIVPPDAVAVDCKDPGDVVPVGQRRAWCWCMCFGLAFMLAGVILGGAYLYKYFALQPDDVYYCGLKYIKDDVILNEPSADAPAARYQTIEENIKIFEEDAVEFISVPVPEFADSDPANIVHDFNKKLTAYLDLNLDKCYVIPLNTSIVMPPKNLLELLINIKAGTYLPQSYLIHEHMVITDRIENVDNLGFFIYRLCHDKETYKLQRRETIRGIQKREASNCFTIRHFENKFAVETLICS |
cAMP catabolic process cellular response to xenobiotic stimulus modulation of chemical synaptic transmission regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway regulation of protein kinase A signaling sensory perception of smell signal transduction | cytoplasm; cytosol; extrinsic component of membrane; membrane; nucleoplasm; nucleus; perinuclear region of cytoplasm; plasma membrane; Schaffer collateral - CA1 synapse | 3',5'-cyclic-AMP phosphodiesterase activity cAMP binding metal ion binding | Mus musculus | Alternative splicing cAMP Cytoplasm Hydrolase Isopeptide bond Magnesium Manganese Membrane Metal-binding Phosphoprotein Reference proteome Ubl conjugation Zinc | MEPPAAPSER | MEPPAAPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERSEPERSPHRPIERADAVDTGDRPGLRTTRMSWPSSFHGTGTGGGSSRRLEAENGPTPSPGRSPLDSQASPGLMLHAGAATSQRRESFLYRSDSDYDMSPKTMSRNSSVASEAHGEDLIVTPFAQVLASLRNVRSNFSLLTNVPIPSNKRSPLGGPPSVCKATLSEETCQQLARETLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTPRQRPFQQPPPAAVQQAQPMSQITGLKKLVHTGSLNINVPRFGVKTDQEDLLAQELENLSKWGLNIFCVSEYAGGRSLSCIMYTIFQERDLLKKFHIPVDTMMTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEENCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNRDWYHSAIRQSPSPTLEEEPGVLSDPALPDKFQFELTLEEEDEEDSLEVPGLPCTEETLLAPHDTRAQAMEQSKVKGQSPAVVEVAESLKQETASAHGAPEESAEAVGHSFSLETSILPDLRTLSPSEEAQGLLGLPSMAAEVEAPRDHLAAMRACSACSGTSGDNSAVISAPGRWGSGGDPA | cAMP catabolic process cellular response to xenobiotic stimulus modulation of chemical synaptic transmission regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway regulation of protein kinase A signaling sensory perception of smell signal transduction cytoplasm; cytosol; extrinsic component of membrane; membrane; nucleoplasm; nucleus; perinuclear region of cytoplasm; plasma membrane; Schaffer collateral - CA1 synapse 3',5'-cyclic-AMP phosphodiesterase activity cAMP binding metal ion binding Mus musculus Alternative splicing cAMP Cytoplasm Hydrolase Isopeptide bond Magnesium Manganese Membrane Metal-binding Phosphoprotein Reference proteome Ubl conjugation Zinc MEPPAAPSER MEPPAAPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERSEPERSPHRPIERADAVDTGDRPGLRTTRMSWPSSFHGTGTGGGSSRRLEAENGPTPSPGRSPLDSQASPGLMLHAGAATSQRRESFLYRSDSDYDMSPKTMSRNSSVASEAHGEDLIVTPFAQVLASLRNVRSNFSLLTNVPIPSNKRSPLGGPPSVCKATLSEETCQQLARETLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTPRQRPFQQPPPAAVQQAQPMSQITGLKKLVHTGSLNINVPRFGVKTDQEDLLAQELENLSKWGLNIFCVSEYAGGRSLSCIMYTIFQERDLLKKFHIPVDTMMTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEENCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNRDWYHSAIRQSPSPTLEEEPGVLSDPALPDKFQFELTLEEEDEEDSLEVPGLPCTEETLLAPHDTRAQAMEQSKVKGQSPAVVEVAESLKQETASAHGAPEESAEAVGHSFSLETSILPDLRTLSPSEEAQGLLGLPSMAAEVEAPRDHLAAMRACSACSGTSGDNSAVISAPGRWGSGGDPA |
miRNA processing positive regulation of mRNA splicing, via spliceosome positive regulation of translation regulation of translation response to cold translation | cytoplasm; dendrite; large ribosomal subunit; nucleoplasm; nucleus; spliceosomal complex | ribosomal large subunit binding RNA binding | Mus musculus | Cell projection Cytoplasm Methylation Nucleus Phosphoprotein Reference proteome RNA-binding Stress response | MSSEEGKLFV | MSSEEGKLFVGGLNFNTDEQALEDHFSSFGPISEVVVVKDRETQRSRGFGFITFTNPEHASDAMRAMNGESLDGRQIRVDHAGKSARGSRGGAFGGRGRSYSRGGGDQGYGSGRYDSRPGGYGYGYGRSRDYSGSQGGYDRYSGGNYRDNYDN | miRNA processing positive regulation of mRNA splicing, via spliceosome positive regulation of translation regulation of translation response to cold translation cytoplasm; dendrite; large ribosomal subunit; nucleoplasm; nucleus; spliceosomal complex ribosomal large subunit binding RNA binding Mus musculus Cell projection Cytoplasm Methylation Nucleus Phosphoprotein Reference proteome RNA-binding Stress response MSSEEGKLFV MSSEEGKLFVGGLNFNTDEQALEDHFSSFGPISEVVVVKDRETQRSRGFGFITFTNPEHASDAMRAMNGESLDGRQIRVDHAGKSARGSRGGAFGGRGRSYSRGGGDQGYGSGRYDSRPGGYGYGYGRSRDYSGSQGGYDRYSGGNYRDNYDN |
bone mineralization cellular response to starvation circadian rhythm negative regulation of DNA-templated transcription positive regulation of osteoclast differentiation positive regulation of transcription by RNA polymerase II regulation of circadian rhythm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II somatic stem cell population maintenance | nucleus | core promoter sequence-specific DNA binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Mus musculus | Biological rhythms DNA-binding Metal-binding Nucleus Phosphoprotein Reference proteome Repeat Repressor Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | MLNFGASLQQ | MLNFGASLQQASEGKMELISEKPREGMHPWDKAEQSDFEAVEALMSMSCDWKSHFKKYLENRPVTPVSDTSEDDSLLPGTPDLQTVPAFCLTPPYSPSDFEPSQGSNLTASAPSTGHFKSFSDAAKPPGATPFKEEEKNPLAAPPLPKAQATSVIRHTADAQLCNHQSCPVKAASILNYQDNSFRRRTHGNVEATRKNIPCAAVSPNRSKPEPSTVSDGDEKAGAALYDFAVPSSETVICRSQPAPSSPVQKSVLVSSPTVSTGGVPPLPVICQMVPLPANNSLVSTVVPSTPPSQPPAVCSPVLFMGTQVPEGTVVFVVPQPVVQSPRPPVVSPSGTRLSPIAPAPGFSPSAARVTPQIDSSRVRSHICSHPGCGKTYFKSSHLKAHVRTHTGEKPFSCSWKGCERRFARSDELSRHRRTHTGEKKFACPMCDRRFMRSDHLTKHARRHLSAKKLPNWQMEVSKLNDIALPPTPASAQ | bone mineralization cellular response to starvation circadian rhythm negative regulation of DNA-templated transcription positive regulation of osteoclast differentiation positive regulation of transcription by RNA polymerase II regulation of circadian rhythm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II somatic stem cell population maintenance nucleus core promoter sequence-specific DNA binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding Mus musculus Biological rhythms DNA-binding Metal-binding Nucleus Phosphoprotein Reference proteome Repeat Repressor Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger MLNFGASLQQ MLNFGASLQQASEGKMELISEKPREGMHPWDKAEQSDFEAVEALMSMSCDWKSHFKKYLENRPVTPVSDTSEDDSLLPGTPDLQTVPAFCLTPPYSPSDFEPSQGSNLTASAPSTGHFKSFSDAAKPPGATPFKEEEKNPLAAPPLPKAQATSVIRHTADAQLCNHQSCPVKAASILNYQDNSFRRRTHGNVEATRKNIPCAAVSPNRSKPEPSTVSDGDEKAGAALYDFAVPSSETVICRSQPAPSSPVQKSVLVSSPTVSTGGVPPLPVICQMVPLPANNSLVSTVVPSTPPSQPPAVCSPVLFMGTQVPEGTVVFVVPQPVVQSPRPPVVSPSGTRLSPIAPAPGFSPSAARVTPQIDSSRVRSHICSHPGCGKTYFKSSHLKAHVRTHTGEKPFSCSWKGCERRFARSDELSRHRRTHTGEKKFACPMCDRRFMRSDHLTKHARRHLSAKKLPNWQMEVSKLNDIALPPTPASAQ |
antimicrobial humoral immune response mediated by antimicrobial peptide calcium-mediated signaling using intracellular calcium source cell chemotaxis cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to type II interferon chemokine-mediated signaling pathway chemotaxis G protein-coupled receptor signaling pathway inflammatory response killing of cells of another organism lymphocyte chemotaxis monocyte chemotaxis neutrophil chemotaxis positive regulation of ERK1 and ERK2 cascade positive regulation of interleukin-1 alpha production positive regulation of nitric-oxide synthase biosynthetic process positive regulation of T cell migration T cell migration thymocyte migration | extracellular space | CCR chemokine receptor binding CCR6 chemokine receptor binding chemokine activity cytokine activity | Mus musculus | 3D-structure Alternative splicing Chemotaxis Cytokine Direct protein sequencing Disulfide bond Inflammatory response Reference proteome Secreted Signal | MACGGKRLLF | MACGGKRLLFLALAWVLLAHLCSQAEAASNYDCCLSYIQTPLPSRAIVGFTRQMADEACDINAIIFHTKKRKSVCADPKQNWVKRAVNLLSLRVKKM | antimicrobial humoral immune response mediated by antimicrobial peptide calcium-mediated signaling using intracellular calcium source cell chemotaxis cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to type II interferon chemokine-mediated signaling pathway chemotaxis G protein-coupled receptor signaling pathway inflammatory response killing of cells of another organism lymphocyte chemotaxis monocyte chemotaxis neutrophil chemotaxis positive regulation of ERK1 and ERK2 cascade positive regulation of interleukin-1 alpha production positive regulation of nitric-oxide synthase biosynthetic process positive regulation of T cell migration T cell migration thymocyte migration extracellular space CCR chemokine receptor binding CCR6 chemokine receptor binding chemokine activity cytokine activity Mus musculus 3D-structure Alternative splicing Chemotaxis Cytokine Direct protein sequencing Disulfide bond Inflammatory response Reference proteome Secreted Signal MACGGKRLLF MACGGKRLLFLALAWVLLAHLCSQAEAASNYDCCLSYIQTPLPSRAIVGFTRQMADEACDINAIIFHTKKRKSVCADPKQNWVKRAVNLLSLRVKKM |
cell differentiation proteolysis | cornified envelope; cytoplasm; cytosol; keratin filament; mitochondrion; nucleoplasm; nucleus | cysteine-type endopeptidase activity peptidase activity | Mus musculus | Alternative splicing Cytoplasm Differentiation Hydrolase Nucleus Protease Reference proteome Thiol protease Zymogen | MESEMSDPQP | MESEMSDPQPLQEERYDMSGARLALTLCVTKAREGSEVDMEALERMFRYLKFESTMKRDPTAQQFLEELDEFQQTIDNWEEPVSCAFVVLMAHGEEGLLKGEDEKMVRLEDLFEVLNNKNCKALRGKPKVYIIQACRGEHRDPGEELRGNEELGGDEELGGDEVAVLKNNPQSIPTYTDTLHIYSTVEGYLSYRHDEKGSGFIQTLTDVFIHKKGSILELTEEITRLMANTEVMQEGKPRKVNPEVQSTLRKKLYLQ | cell differentiation proteolysis cornified envelope; cytoplasm; cytosol; keratin filament; mitochondrion; nucleoplasm; nucleus cysteine-type endopeptidase activity peptidase activity Mus musculus Alternative splicing Cytoplasm Differentiation Hydrolase Nucleus Protease Reference proteome Thiol protease Zymogen MESEMSDPQP MESEMSDPQPLQEERYDMSGARLALTLCVTKAREGSEVDMEALERMFRYLKFESTMKRDPTAQQFLEELDEFQQTIDNWEEPVSCAFVVLMAHGEEGLLKGEDEKMVRLEDLFEVLNNKNCKALRGKPKVYIIQACRGEHRDPGEELRGNEELGGDEELGGDEVAVLKNNPQSIPTYTDTLHIYSTVEGYLSYRHDEKGSGFIQTLTDVFIHKKGSILELTEEITRLMANTEVMQEGKPRKVNPEVQSTLRKKLYLQ |
immune response negative regulation of microglial cell activation negative regulation of peptidase activity positive regulation of myelination | cytoplasm; cytoplasmic vesicle; endoplasmic reticulum; endosome; extracellular space; Golgi apparatus; late endosome; lysosome; multivesicular body | cysteine-type endopeptidase inhibitor activity peptidase inhibitor activity protein homodimerization activity | Mus musculus | Disulfide bond Glycoprotein Protease inhibitor Reference proteome Secreted Signal Thiol protease inhibitor | MWLAILLALC | MWLAILLALCCLTSDTHGARPPDFCSKDLISSVKPGFPKTIETNNPGVLKAARHSVEKFNNCTNDIFLFKESHVSKALVQVVKGLKYMLEVKIGRTTCRKTMHHQLDNCDFQTNPALKRTLYCYSEVWVIPWLHSFEVPVLLCQ | immune response negative regulation of microglial cell activation negative regulation of peptidase activity positive regulation of myelination cytoplasm; cytoplasmic vesicle; endoplasmic reticulum; endosome; extracellular space; Golgi apparatus; late endosome; lysosome; multivesicular body cysteine-type endopeptidase inhibitor activity peptidase inhibitor activity protein homodimerization activity Mus musculus Disulfide bond Glycoprotein Protease inhibitor Reference proteome Secreted Signal Thiol protease inhibitor MWLAILLALC MWLAILLALCCLTSDTHGARPPDFCSKDLISSVKPGFPKTIETNNPGVLKAARHSVEKFNNCTNDIFLFKESHVSKALVQVVKGLKYMLEVKIGRTTCRKTMHHQLDNCDFQTNPALKRTLYCYSEVWVIPWLHSFEVPVLLCQ |
regulation of MAPK cascade signal transduction | cytoplasm; cytosol; endosome; nucleoplasm; nucleus; plasma membrane | phosphotyrosine residue binding | Mus musculus | 3D-structure Acetylation Cytoplasm Endosome Nucleus Phosphoprotein Reference proteome Repeat SH2 domain SH3 domain | MEATAKFDFM | MEATAKFDFMASGEDELSFRTGDILKILSNQEEWLKAELGSQEGYVPKNFIDIEFPEWFHEGLSRHQAENLLMGKDIGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDTKGNYFLWTEKFPSLNKLVDYYRTTSISKQKQVFLRDGTQDQGHRGNSLDRRSQGGPHPSGTVGEEIRPSVNRKLSDHLPLGPQQFHPHQQPSPQFTPGPQPPQQQRYLQHFHQDRRGGSLDINDGHCGLGSEVNATLMHRRHTDPVQLQAAGRVRWARALYDFEALEEDELGFRSGEVVEVLDSSNPSWWTGRLHNKLGLFPANYVAPMMR | regulation of MAPK cascade signal transduction cytoplasm; cytosol; endosome; nucleoplasm; nucleus; plasma membrane phosphotyrosine residue binding Mus musculus 3D-structure Acetylation Cytoplasm Endosome Nucleus Phosphoprotein Reference proteome Repeat SH2 domain SH3 domain MEATAKFDFM MEATAKFDFMASGEDELSFRTGDILKILSNQEEWLKAELGSQEGYVPKNFIDIEFPEWFHEGLSRHQAENLLMGKDIGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDTKGNYFLWTEKFPSLNKLVDYYRTTSISKQKQVFLRDGTQDQGHRGNSLDRRSQGGPHPSGTVGEEIRPSVNRKLSDHLPLGPQQFHPHQQPSPQFTPGPQPPQQQRYLQHFHQDRRGGSLDINDGHCGLGSEVNATLMHRRHTDPVQLQAAGRVRWARALYDFEALEEDELGFRSGEVVEVLDSSNPSWWTGRLHNKLGLFPANYVAPMMR |
angiogenesis animal organ morphogenesis cell differentiation cell population proliferation chondrocyte development chondrocyte differentiation endochondral ossification ERK1 and ERK2 cascade fibroblast growth factor receptor signaling pathway intramembranous ossification lung development nervous system development ossification positive regulation of angiogenesis positive regulation of blood vessel endothelial cell migration positive regulation of cell population proliferation positive regulation of chondrocyte differentiation positive regulation of endothelial cell chemotaxis to fibroblast growth factor positive regulation of ERK1 and ERK2 cascade positive regulation of gene expression positive regulation of hepatocyte proliferation positive regulation of protein phosphorylation positive regulation of vascular endothelial growth factor receptor signaling pathway regulation of cell migration signal transduction vascular endothelial growth factor receptor signaling pathway | cytoplasm; extracellular space; nucleolus; nucleus | fibroblast growth factor receptor binding growth factor activity type 1 fibroblast growth factor receptor binding type 2 fibroblast growth factor receptor binding | Mus musculus | Disulfide bond Glycoprotein Growth factor Reference proteome Secreted Signal | MYSAPSACTC | MYSAPSACTCLCLHFLLLCFQVQVLAAEENVDFRIHVENQTRARDDVSRKQLRLYQLYSRTSGKHIQVLGRRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLCMNRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYSGWYVGFTKKGRPRKGPKTRENQQDVHFMKRYPKGQAELQKPFKYTTVTKRSRRIRPTHPG | angiogenesis animal organ morphogenesis cell differentiation cell population proliferation chondrocyte development chondrocyte differentiation endochondral ossification ERK1 and ERK2 cascade fibroblast growth factor receptor signaling pathway intramembranous ossification lung development nervous system development ossification positive regulation of angiogenesis positive regulation of blood vessel endothelial cell migration positive regulation of cell population proliferation positive regulation of chondrocyte differentiation positive regulation of endothelial cell chemotaxis to fibroblast growth factor positive regulation of ERK1 and ERK2 cascade positive regulation of gene expression positive regulation of hepatocyte proliferation positive regulation of protein phosphorylation positive regulation of vascular endothelial growth factor receptor signaling pathway regulation of cell migration signal transduction vascular endothelial growth factor receptor signaling pathway cytoplasm; extracellular space; nucleolus; nucleus fibroblast growth factor receptor binding growth factor activity type 1 fibroblast growth factor receptor binding type 2 fibroblast growth factor receptor binding Mus musculus Disulfide bond Glycoprotein Growth factor Reference proteome Secreted Signal MYSAPSACTC MYSAPSACTCLCLHFLLLCFQVQVLAAEENVDFRIHVENQTRARDDVSRKQLRLYQLYSRTSGKHIQVLGRRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLCMNRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYSGWYVGFTKKGRPRKGPKTRENQQDVHFMKRYPKGQAELQKPFKYTTVTKRSRRIRPTHPG |
cell-cell adhesion | cell surface; cytoplasmic vesicle; plasma membrane | calcium ion binding carbohydrate binding complement component C1q complex binding | Mus musculus | Cell adhesion Disulfide bond EGF-like domain Glycoprotein Lectin Membrane Phosphoprotein Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix | MAISTGLFLL | MAISTGLFLLLGLLGQPWAGAAADSQAVVCEGTACYTAHWGKLSAAEAQHRCNENGGNLATVKSEEEARHVQQALTQLLKTKAPLEAKMGKFWIGLQREKGNCTYHDLPMRGFSWVGGGEDTAYSNWYKASKSSCIFKRCVSLILDLSLTPHPSHLPKWHESPCGTPEAPGNSIEGFLCKFNFKGMCRPLALGGPGRVTYTTPFQATTSSLEAVPFASVANVACGDEAKSETHYFLCNEKTPGIFHWGSSGPLCVSPKFGCSFNNGGCQQDCFEGGDGSFRCGCRPGFRLLDDLVTCASRNPCSSNPCTGGGMCHSVPLSENYTCRCPSGYQLDSSQVHCVDIDECQDSPCAQDCVNTLGSFHCECWVGYQPSGPKEEACEDVDECAAANSPCAQGCINTDGSFYCSCKEGYIVSGEDSTQCEDIDECSDARGNPCDSLCFNTDGSFRCGCPPGWELAPNGVFCSRGTVFSELPARPPQKEDNDDRKESTMPPTEMPSSPSGSKDVSNRAQTTGLFVQSDIPTASVPLEIEIPSEVSDVWFELGTYLPTTSGHSKPTHEDSVSAHSDTDGQNLLLFYILGTVVAISLLLVLALGILIYHKRRAKKEEIKEKKPQNAADSYSWVPERAESQAPENQYSPTPGTDC | cell-cell adhesion cell surface; cytoplasmic vesicle; plasma membrane calcium ion binding carbohydrate binding complement component C1q complex binding Mus musculus Cell adhesion Disulfide bond EGF-like domain Glycoprotein Lectin Membrane Phosphoprotein Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix MAISTGLFLL MAISTGLFLLLGLLGQPWAGAAADSQAVVCEGTACYTAHWGKLSAAEAQHRCNENGGNLATVKSEEEARHVQQALTQLLKTKAPLEAKMGKFWIGLQREKGNCTYHDLPMRGFSWVGGGEDTAYSNWYKASKSSCIFKRCVSLILDLSLTPHPSHLPKWHESPCGTPEAPGNSIEGFLCKFNFKGMCRPLALGGPGRVTYTTPFQATTSSLEAVPFASVANVACGDEAKSETHYFLCNEKTPGIFHWGSSGPLCVSPKFGCSFNNGGCQQDCFEGGDGSFRCGCRPGFRLLDDLVTCASRNPCSSNPCTGGGMCHSVPLSENYTCRCPSGYQLDSSQVHCVDIDECQDSPCAQDCVNTLGSFHCECWVGYQPSGPKEEACEDVDECAAANSPCAQGCINTDGSFYCSCKEGYIVSGEDSTQCEDIDECSDARGNPCDSLCFNTDGSFRCGCPPGWELAPNGVFCSRGTVFSELPARPPQKEDNDDRKESTMPPTEMPSSPSGSKDVSNRAQTTGLFVQSDIPTASVPLEIEIPSEVSDVWFELGTYLPTTSGHSKPTHEDSVSAHSDTDGQNLLLFYILGTVVAISLLLVLALGILIYHKRRAKKEEIKEKKPQNAADSYSWVPERAESQAPENQYSPTPGTDC |
diadenosine triphosphate catabolic process DNA replication intrinsic apoptotic signaling pathway by p53 class mediator negative regulation of proteasomal ubiquitin-dependent protein catabolic process purine nucleotide metabolic process | cytoplasm; cytosol; fibrillar center; mitochondrion; nucleus; plasma membrane | adenosine 5'-monophosphoramidase activity adenylylsulfatase activity adenylylsulfate-ammonia adenylyltransferase activity bis(5'-adenosyl)-triphosphatase activity identical protein binding nickel cation binding nucleotide binding ubiquitin protein ligase binding | Mus musculus | Apoptosis Cytoplasm Hydrolase Magnesium Manganese Mitochondrion Nucleotide-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Transferase | MSFRFGQHLI | MSFRFGQHLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPLRPVERFRDLHPDEVADLFQVTQRVGTVVEKHFQGTSITFSMQDGPEAGQTVKHVHVHVLPRKAGDFPRNDNIYDELQKHDREEEDSPAFWRSEKEMAAEAEALRVYFQA | diadenosine triphosphate catabolic process DNA replication intrinsic apoptotic signaling pathway by p53 class mediator negative regulation of proteasomal ubiquitin-dependent protein catabolic process purine nucleotide metabolic process cytoplasm; cytosol; fibrillar center; mitochondrion; nucleus; plasma membrane adenosine 5'-monophosphoramidase activity adenylylsulfatase activity adenylylsulfate-ammonia adenylyltransferase activity bis(5'-adenosyl)-triphosphatase activity identical protein binding nickel cation binding nucleotide binding ubiquitin protein ligase binding Mus musculus Apoptosis Cytoplasm Hydrolase Magnesium Manganese Mitochondrion Nucleotide-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Transferase MSFRFGQHLI MSFRFGQHLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPLRPVERFRDLHPDEVADLFQVTQRVGTVVEKHFQGTSITFSMQDGPEAGQTVKHVHVHVLPRKAGDFPRNDNIYDELQKHDREEEDSPAFWRSEKEMAAEAEALRVYFQA |
apoptotic DNA fragmentation DNA catabolic process neutrophil activation involved in immune response programmed cell death involved in cell development regulation of acute inflammatory response regulation of neutrophil mediated cytotoxicity | endoplasmic reticulum; extracellular region; nucleus | deoxyribonuclease I activity DNA binding DNA endonuclease activity endonuclease activity | Rattus norvegicus | ADP-ribosylation Apoptosis Calcium Direct protein sequencing Disulfide bond Endonuclease Hydrolase Nuclease Nucleus Reference proteome Secreted Signal | MSLYPASPYL | MSLYPASPYLASLLLFILALHGALSLRLCSFNVRSFGESKKENHNAMDIIVKIIKRCDLILLMEIKDSNNNICPMLMEKLNGNSRRSTTYNYVISSRLGRNTYKEQYAFLYKEKLVSVKAKYLYHDYQDGDTDVFSREPFVVWFQAPFTAAKDFVIVPLHTTPETSVKEIDELADVYTDVRRRWKAENFIFMGDFNAGCSYVPKKAWKNIRLRTDPNFVWLIGDQEDTTVKKSTSCAYDRIVLRGQEIVNSVVPRSSGVFDFQKAYELSEEEALDVSDHFPVEFKLQSSRAFTNSRKSVSLKKKKKGSRS | apoptotic DNA fragmentation DNA catabolic process neutrophil activation involved in immune response programmed cell death involved in cell development regulation of acute inflammatory response regulation of neutrophil mediated cytotoxicity endoplasmic reticulum; extracellular region; nucleus deoxyribonuclease I activity DNA binding DNA endonuclease activity endonuclease activity Rattus norvegicus ADP-ribosylation Apoptosis Calcium Direct protein sequencing Disulfide bond Endonuclease Hydrolase Nuclease Nucleus Reference proteome Secreted Signal MSLYPASPYL MSLYPASPYLASLLLFILALHGALSLRLCSFNVRSFGESKKENHNAMDIIVKIIKRCDLILLMEIKDSNNNICPMLMEKLNGNSRRSTTYNYVISSRLGRNTYKEQYAFLYKEKLVSVKAKYLYHDYQDGDTDVFSREPFVVWFQAPFTAAKDFVIVPLHTTPETSVKEIDELADVYTDVRRRWKAENFIFMGDFNAGCSYVPKKAWKNIRLRTDPNFVWLIGDQEDTTVKKSTSCAYDRIVLRGQEIVNSVVPRSSGVFDFQKAYELSEEEALDVSDHFPVEFKLQSSRAFTNSRKSVSLKKKKKGSRS |
carbohydrate metabolic process cellular detoxification peptide modification | cytoplasm; plasma membrane | glutathione binding glutathione transferase activity low-density lipoprotein particle receptor binding SH3 domain binding zinc ion binding | Mus musculus | Acetylation Cell membrane Cytoplasm Membrane Metal-binding Reference proteome Transferase Zinc | MAQRAFPNPY | MAQRAFPNPYADYNKSLAENYFDSTGRLTPEFSHRLTNKIRELLQQMERGLKSADPRDGTGYTGWAGIAVLYLHLHNVFGDPAYLQMAHSYVKQSLNCLSRRSITFLCGDAGPLAVAAVLYHKMNSEKQAEECITRLIHLNKIDPHVPNEMLYGRIGYIFALLFVNKNFGEEKIPQSHIQQICENILTSGENLSRKRNLAAKSPLMYEWYQEYYVGAAHGLAGIYYYLMQPSLQVNQGKLHSLVKPSVDFVCRLKFPSGNYPPCLDDTRDLLVHWCHGAPGVIYMLIQAYKVFKEERYLCDAQQCADVIWQYGLLKKGYGLCHGAAGNAYAFLALYNLTQDLKYLYRACKFAEWCLDYGEHGCRTADTPFSLFEGMAGTIYFLADLLVPTKAKFPAFEL | carbohydrate metabolic process cellular detoxification peptide modification cytoplasm; plasma membrane glutathione binding glutathione transferase activity low-density lipoprotein particle receptor binding SH3 domain binding zinc ion binding Mus musculus Acetylation Cell membrane Cytoplasm Membrane Metal-binding Reference proteome Transferase Zinc MAQRAFPNPY MAQRAFPNPYADYNKSLAENYFDSTGRLTPEFSHRLTNKIRELLQQMERGLKSADPRDGTGYTGWAGIAVLYLHLHNVFGDPAYLQMAHSYVKQSLNCLSRRSITFLCGDAGPLAVAAVLYHKMNSEKQAEECITRLIHLNKIDPHVPNEMLYGRIGYIFALLFVNKNFGEEKIPQSHIQQICENILTSGENLSRKRNLAAKSPLMYEWYQEYYVGAAHGLAGIYYYLMQPSLQVNQGKLHSLVKPSVDFVCRLKFPSGNYPPCLDDTRDLLVHWCHGAPGVIYMLIQAYKVFKEERYLCDAQQCADVIWQYGLLKKGYGLCHGAAGNAYAFLALYNLTQDLKYLYRACKFAEWCLDYGEHGCRTADTPFSLFEGMAGTIYFLADLLVPTKAKFPAFEL |
autophagy endocytic recycling endoplasmic reticulum to Golgi vesicle-mediated transport Golgi to vacuole transport intra-Golgi vesicle-mediated transport intracellular protein transport macroautophagy retrograde transport, endosome to Golgi synaptic vesicle to endosome fusion vesicle fusion with Golgi apparatus voluntary musculoskeletal movement | autophagosome; clathrin-coated vesicle; cytosol; endoplasmic reticulum membrane; endosome; ER to Golgi transport vesicle membrane; Golgi apparatus; Golgi membrane; hippocampal mossy fiber to CA3 synapse; intracellular membrane-bounded organelle; late endosome membrane; neuron projection terminus; neuronal cell body; perinuclear region of cytoplasm; SNARE complex; synaptic vesicle | SNAP receptor activity SNARE binding | Mus musculus | 3D-structure Coiled coil Golgi apparatus Membrane Protein transport Reference proteome Transmembrane Transmembrane helix Transport | MSSDFEGYEQ | MSSDFEGYEQDFAVLTAEITSKIARVPRLPPDEKKQMVANVEKQLEEARELLEQMDLEVREIPPQSRGMYSNRMRSYKQEMGKLETDFKRSRIAYSDEVRNELLGDAGNSSENQRAHLLDNTERLERSSRRLEAGYQIAVETEQIGQEMLENLSHDREKIQRARDRLRDADANLGKSSRILTGMLRRIIQNRILLVILGIIVVIAILTAIAFFVKGH | autophagy endocytic recycling endoplasmic reticulum to Golgi vesicle-mediated transport Golgi to vacuole transport intra-Golgi vesicle-mediated transport intracellular protein transport macroautophagy retrograde transport, endosome to Golgi synaptic vesicle to endosome fusion vesicle fusion with Golgi apparatus voluntary musculoskeletal movement autophagosome; clathrin-coated vesicle; cytosol; endoplasmic reticulum membrane; endosome; ER to Golgi transport vesicle membrane; Golgi apparatus; Golgi membrane; hippocampal mossy fiber to CA3 synapse; intracellular membrane-bounded organelle; late endosome membrane; neuron projection terminus; neuronal cell body; perinuclear region of cytoplasm; SNARE complex; synaptic vesicle SNAP receptor activity SNARE binding Mus musculus 3D-structure Coiled coil Golgi apparatus Membrane Protein transport Reference proteome Transmembrane Transmembrane helix Transport MSSDFEGYEQ MSSDFEGYEQDFAVLTAEITSKIARVPRLPPDEKKQMVANVEKQLEEARELLEQMDLEVREIPPQSRGMYSNRMRSYKQEMGKLETDFKRSRIAYSDEVRNELLGDAGNSSENQRAHLLDNTERLERSSRRLEAGYQIAVETEQIGQEMLENLSHDREKIQRARDRLRDADANLGKSSRILTGMLRRIIQNRILLVILGIIVVIAILTAIAFFVKGH |
viral budding via host ESCRT complex | host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane | RNA binding structural molecule activity zinc ion binding | Human immunodeficiency virus type 1 group M subtype F1 | AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Methylation Myristate Phosphoprotein Reference proteome Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucleoprotein Viral release from host cell Virion Zinc Zinc-finger | MGARASVLSG | MGARASVLSGGKLDAWEKIRLRPGGKKKYRLKHLVWASRELERFALDPGLLETSEGCRKIIGQLQPSLQTGSEELKSLYNTIAVLYYVHQKVEVKDTKEALEKLEEEQNKGRQKTQQATAEKGVSQNYPIVQNLQGQMVHQSLSPRTLNAWVKVIEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKDTINEEAAEWDRLHPTQAGPIPPGQIREPRGSDIAGTTSTLQEQIQWMTGNPPVPVGEMYKRWIILGLNKIVRMYSPVGILDIRQGPKEPFRDYVDRFFKTLRAEQATQEVKGWMTDTLLVQNANPDCKTILKALGPGATLEEMMTACQGVGGPSHKARVLAEAMSQATNTAIMMQKSNFKGQRRIVKCFNCGKEGHIAKNCRAPRKKGCWKCGREGHQMKDCTERQANFLGKIWPSNKGRPGNFIQNRPEPSAPPAESFRFGEETTPSPKQEQKDEGLYPPLASLKSLFGNDP | viral budding via host ESCRT complex host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane RNA binding structural molecule activity zinc ion binding Human immunodeficiency virus type 1 group M subtype F1 AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Methylation Myristate Phosphoprotein Reference proteome Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucleoprotein Viral release from host cell Virion Zinc Zinc-finger MGARASVLSG MGARASVLSGGKLDAWEKIRLRPGGKKKYRLKHLVWASRELERFALDPGLLETSEGCRKIIGQLQPSLQTGSEELKSLYNTIAVLYYVHQKVEVKDTKEALEKLEEEQNKGRQKTQQATAEKGVSQNYPIVQNLQGQMVHQSLSPRTLNAWVKVIEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKDTINEEAAEWDRLHPTQAGPIPPGQIREPRGSDIAGTTSTLQEQIQWMTGNPPVPVGEMYKRWIILGLNKIVRMYSPVGILDIRQGPKEPFRDYVDRFFKTLRAEQATQEVKGWMTDTLLVQNANPDCKTILKALGPGATLEEMMTACQGVGGPSHKARVLAEAMSQATNTAIMMQKSNFKGQRRIVKCFNCGKEGHIAKNCRAPRKKGCWKCGREGHQMKDCTERQANFLGKIWPSNKGRPGNFIQNRPEPSAPPAESFRFGEETTPSPKQEQKDEGLYPPLASLKSLFGNDP |
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral protein processing virion attachment to host cell virus-mediated perturbation of host defense response | host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane | structural molecule activity | Human immunodeficiency virus type 1 group M subtype F1 | AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Palmitate Reference proteome Signal Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Viral immunoevasion Viral penetration into host cytoplasm Virion Virus endocytosis by host Virus entry into host cell | MRVRGMQRNW | MRVRGMQRNWQHLGKWGLLFLGTLIICNAAENLWVTVYYGVPVWKEATTTLFCASDAKSYEKEAHNVWATHACVPTDPNPQEVVLENVTERFNMWENNMVEQMHTDIISLWDQSLKPCVKLTPLCVTLDCRNIATNGTNDTIAINDTLKEDPEAIQNCSFNTTTEIRDKQLKVHALFYKLDIVQINKDDNRTYRLINCDASTITQACPKVSWDPIPIHYCAPAGYAILKCNEKNFTGTGSCKNVSTVQCTHGIKPVVSTQLLLNGSLAEGEIVIRSQNISDNAKTIIVHLNESVQINCTRPNNNTRKRISLGPGRVFYTTGEIIGDIRKAHCNVSGTQWRNTLAKVKAKLGSYFPNATIKFNSSSGGDLEITRHNFNCMGEFFYCNTDELFNDTKFNDTGFNGTITLPCRIKQIVNMWQEVGRAMYANPIAGNITCNSNITGLLLTRDGGLNSTNETFRPGGGNMKDNWRSELYKYKVVEIEPLGVAPTKAKRQVVKRERRAVGLGALFLGFLGAAGSTMGAASITLTVQARQLLSGIVQQQSNLLRAIEAQQHLLQLTVWGIKQLQARVLAVERYLKDQQLLGLWGCSGKLICTTNVPWNSSWSNKSLEEIWGNMTWMEWEKEVSNYSKEIYRLIEDSQNQQEKNEQELLALDKWASLWNWFDITQWLWYIKIFIMIVGGLIGLRIVFTVLSIVNRVRKGYSPLSFQTHIPSPREPDRPEGIEEGGGEQGKDRSVRLVTGFLALAWDDLRNLCLFSYRHLRDFILIAARIVDRGLKRGWEALKYLGNLTQYWGQELKNSAISLLNATAIAVAEWTDRVIEALQRAGRAILNIPRRIRQGLERALL | clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral protein processing virion attachment to host cell virus-mediated perturbation of host defense response host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane structural molecule activity Human immunodeficiency virus type 1 group M subtype F1 AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Palmitate Reference proteome Signal Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Viral immunoevasion Viral penetration into host cytoplasm Virion Virus endocytosis by host Virus entry into host cell MRVRGMQRNW MRVRGMQRNWQHLGKWGLLFLGTLIICNAAENLWVTVYYGVPVWKEATTTLFCASDAKSYEKEAHNVWATHACVPTDPNPQEVVLENVTERFNMWENNMVEQMHTDIISLWDQSLKPCVKLTPLCVTLDCRNIATNGTNDTIAINDTLKEDPEAIQNCSFNTTTEIRDKQLKVHALFYKLDIVQINKDDNRTYRLINCDASTITQACPKVSWDPIPIHYCAPAGYAILKCNEKNFTGTGSCKNVSTVQCTHGIKPVVSTQLLLNGSLAEGEIVIRSQNISDNAKTIIVHLNESVQINCTRPNNNTRKRISLGPGRVFYTTGEIIGDIRKAHCNVSGTQWRNTLAKVKAKLGSYFPNATIKFNSSSGGDLEITRHNFNCMGEFFYCNTDELFNDTKFNDTGFNGTITLPCRIKQIVNMWQEVGRAMYANPIAGNITCNSNITGLLLTRDGGLNSTNETFRPGGGNMKDNWRSELYKYKVVEIEPLGVAPTKAKRQVVKRERRAVGLGALFLGFLGAAGSTMGAASITLTVQARQLLSGIVQQQSNLLRAIEAQQHLLQLTVWGIKQLQARVLAVERYLKDQQLLGLWGCSGKLICTTNVPWNSSWSNKSLEEIWGNMTWMEWEKEVSNYSKEIYRLIEDSQNQQEKNEQELLALDKWASLWNWFDITQWLWYIKIFIMIVGGLIGLRIVFTVLSIVNRVRKGYSPLSFQTHIPSPREPDRPEGIEEGGGEQGKDRSVRLVTGFLALAWDDLRNLCLFSYRHLRDFILIAARIVDRGLKRGWEALKYLGNLTQYWGQELKNSAISLLNATAIAVAEWTDRVIEALQRAGRAILNIPRRIRQGLERALL |
suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy | extracellular region; host cell Golgi membrane; host cell plasma membrane; membrane; virion component | GTP binding SH3 domain binding | Human immunodeficiency virus type 1 group M subtype F1 | AIDS Apoptosis Early protein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host autophagy by virus Inhibition of host MHC class I molecule presentation by virus Inhibition of host MHC class II molecule presentation by virus Lipoprotein Membrane Myristate Phosphoprotein Reference proteome Secreted SH3-binding Viral immunoevasion Virion Virulence | MGGKWSKSSI | MGGKWSKSSIVGWPAIRERMRRTPPTPPAAEGVGAVSQDLERRGAITSSNTRANNPDLAWLEAQEEDEVGFPVRPQVPLRPMTYKGAVDLSHFLKEKGGLEGLIYSKRRQEILDLWVYHTQGYFPDWQNYTPGPGIRYPLTMGWCFKLVPVDPEEVEKANEGENNCLLHPMSQHGMEDEDKEVLKWEFDSRLALRHIARERHPEYYQD | suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy extracellular region; host cell Golgi membrane; host cell plasma membrane; membrane; virion component GTP binding SH3 domain binding Human immunodeficiency virus type 1 group M subtype F1 AIDS Apoptosis Early protein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host autophagy by virus Inhibition of host MHC class I molecule presentation by virus Inhibition of host MHC class II molecule presentation by virus Lipoprotein Membrane Myristate Phosphoprotein Reference proteome Secreted SH3-binding Viral immunoevasion Virion Virulence MGGKWSKSSI MGGKWSKSSIVGWPAIRERMRRTPPTPPAAEGVGAVSQDLERRGAITSSNTRANNPDLAWLEAQEEDEVGFPVRPQVPLRPMTYKGAVDLSHFLKEKGGLEGLIYSKRRQEILDLWVYHTQGYFPDWQNYTPGPGIRYPLTMGWCFKLVPVDPEEVEKANEGENNCLLHPMSQHGMEDEDKEVLKWEFDSRLALRHIARERHPEYYQD |
viral budding via host ESCRT complex | host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane | RNA binding structural molecule activity zinc ion binding | Human immunodeficiency virus type 1 group M subtype G | AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Methylation Myristate Phosphoprotein Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucleoprotein Viral release from host cell Virion Zinc Zinc-finger | MGARASVLTG | MGARASVLTGGKLDAWEKIRLRPGGRKSYKIKHLVWASRELERFALNPDLLETAEGCQQIMRQLQPSLQTGTEEIKSLYNAVATLYCVHQRIEVKDTKEALEEVEKIQKKSQEKIQQAAMDKGNSNQVSQNYPIVQNAQGQMVHQAITPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNLMLNTVGGHQAAMQMLKDTINEEAAEWDRMHPQQAGPFPPGQIREPRGSDIAGTTSSLQEQITWMTGNPPIPVGEIYKRWIILGLNKIVRMYSPVSILDIRQGPKEPFRDYVDRFFKCLRAEQASQDVKGWMTDTLLVQNANPDCKTILRALGQGASLEEMMTACQGVGGPSHKARVLAEAMSQASGAAAAIMMQRSNFKGPRRTIKCFNCGKEGHLARNCRAPRKKGCWKCGKEGHQMKDCTERQANFLGKIWPSNKGRPGNFLQNRTEPTAPPAESLGFGEEIAPSPKQEMKEKELYPSLKSLFGSDP | viral budding via host ESCRT complex host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane RNA binding structural molecule activity zinc ion binding Human immunodeficiency virus type 1 group M subtype G AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Methylation Myristate Phosphoprotein Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucleoprotein Viral release from host cell Virion Zinc Zinc-finger MGARASVLTG MGARASVLTGGKLDAWEKIRLRPGGRKSYKIKHLVWASRELERFALNPDLLETAEGCQQIMRQLQPSLQTGTEEIKSLYNAVATLYCVHQRIEVKDTKEALEEVEKIQKKSQEKIQQAAMDKGNSNQVSQNYPIVQNAQGQMVHQAITPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNLMLNTVGGHQAAMQMLKDTINEEAAEWDRMHPQQAGPFPPGQIREPRGSDIAGTTSSLQEQITWMTGNPPIPVGEIYKRWIILGLNKIVRMYSPVSILDIRQGPKEPFRDYVDRFFKCLRAEQASQDVKGWMTDTLLVQNANPDCKTILRALGQGASLEEMMTACQGVGGPSHKARVLAEAMSQASGAAAAIMMQRSNFKGPRRTIKCFNCGKEGHLARNCRAPRKKGCWKCGKEGHQMKDCTERQANFLGKIWPSNKGRPGNFLQNRTEPTAPPAESLGFGEEIAPSPKQEMKEKELYPSLKSLFGSDP |
DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by virus of host type I interferon-mediated signaling pathway | extracellular region; host cell cytoplasm; host cell nucleolus | actinin binding cyclin binding metal ion binding protein domain specific binding protein serine/threonine phosphatase inhibitor activity RNA-binding transcription regulator activity trans-activation response element binding | Human immunodeficiency virus type 1 group M subtype G | Acetylation Activator AIDS Alternative splicing Apoptosis Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Isopeptide bond Metal-binding Methylation Modulation of host chromatin by virus Modulation of host PP1 activity by virus Phosphoprotein RNA-binding Secreted Transcription Transcription regulation Ubl conjugation Viral immunoevasion Zinc | MDPVDPNLEP | MDPVDPNLEPWNHPGSQPKTPCNKCFCKVCCWHCQVCFLNKGLGISYGRKKRKHRRGTPQSSKGHQDPVPKQPLPTTRGNPTGPKESKKEVASKAEADQCD | DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by virus of host type I interferon-mediated signaling pathway extracellular region; host cell cytoplasm; host cell nucleolus actinin binding cyclin binding metal ion binding protein domain specific binding protein serine/threonine phosphatase inhibitor activity RNA-binding transcription regulator activity trans-activation response element binding Human immunodeficiency virus type 1 group M subtype G Acetylation Activator AIDS Alternative splicing Apoptosis Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Isopeptide bond Metal-binding Methylation Modulation of host chromatin by virus Modulation of host PP1 activity by virus Phosphoprotein RNA-binding Secreted Transcription Transcription regulation Ubl conjugation Viral immunoevasion Zinc MDPVDPNLEP MDPVDPNLEPWNHPGSQPKTPCNKCFCKVCCWHCQVCFLNKGLGISYGRKKRKHRRGTPQSSKGHQDPVPKQPLPTTRGNPTGPKESKKEVASKAEADQCD |
suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy | extracellular region; host cell Golgi membrane; host cell plasma membrane; membrane; virion component | GTP binding SH3 domain binding | Human immunodeficiency virus type 1 group M subtype G | AIDS Apoptosis Early protein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host autophagy by virus Inhibition of host MHC class I molecule presentation by virus Inhibition of host MHC class II molecule presentation by virus Lipoprotein Membrane Myristate Phosphoprotein Secreted SH3-binding Viral immunoevasion Virion Virulence | MGGKWSKSSI | MGGKWSKSSIVGWPEVRERIRNTPTAAEGVGAVSQDLDRHGAITSSNTAANNPDCAWLEAQEEDSEVGFPVRPQVPLRPMTFKGAFDLSFFLKEKGGLDGLIYSKKRQEILDLWVYNTQGYFPDWQNYTPGPGTRFPLTFGWCFKLVPMDPAEVEEANKGENNSLLHPICQHGMEDEDREVLVWRFDSSLARRHIARELHPEYYKDC | suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy extracellular region; host cell Golgi membrane; host cell plasma membrane; membrane; virion component GTP binding SH3 domain binding Human immunodeficiency virus type 1 group M subtype G AIDS Apoptosis Early protein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host autophagy by virus Inhibition of host MHC class I molecule presentation by virus Inhibition of host MHC class II molecule presentation by virus Lipoprotein Membrane Myristate Phosphoprotein Secreted SH3-binding Viral immunoevasion Virion Virulence MGGKWSKSSI MGGKWSKSSIVGWPEVRERIRNTPTAAEGVGAVSQDLDRHGAITSSNTAANNPDCAWLEAQEEDSEVGFPVRPQVPLRPMTFKGAFDLSFFLKEKGGLDGLIYSKKRQEILDLWVYNTQGYFPDWQNYTPGPGTRFPLTFGWCFKLVPMDPAEVEEANKGENNSLLHPICQHGMEDEDREVLVWRFDSSLARRHIARELHPEYYKDC |
viral budding via host ESCRT complex | host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane | RNA binding structural molecule activity zinc ion binding | Human immunodeficiency virus type 1 group N | AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Methylation Myristate Phosphoprotein Reference proteome Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucleoprotein Viral release from host cell Virion Zinc Zinc-finger | MGARASVLTG | MGARASVLTGGKLDQWESIYLRPGGKKKYRMKHLVWASRELERFACNPGLMDTADGCAKLLNQLEPALKTGSEELRSLYNALAVLYCVHSRIQIHNTQEALDKIKEKQEQHKPEPKNPEAGAAAATDSNISRNYPLVQTAQGQMVHQPLTPRTLNAWVKVIEEKAFSPEVIPMFMALSEGATPSDLNTMLNTVGGHQAAMQMLKEVINEEAADWDRTHPVPVGPLPPGQLRDPRGSDIAGTTSTLAEQVAWMTANPPVPVGDIYRRWIVLGLNRIVRMYSPVSILEIKQGPKEPFRDYVDRFYKTLRAEQATQEVKNWMTETLLVQNANPDCKQLLKALGPGATLEEMMTACQGVGGPAHKARVLAEAMSQVQQPTTSVFAQRGNFKGIRKPIKCFNCGKEGHLARNCKAPRRGGCWKCGQEGHQMKDCKNEGRQANFLGKSWSPFKGRPGNFPQTTTRKEPTAPPLESYGFQEEKSTQGKEMQENQERTENSLYPPLTSLRSLFGNDPSSQ | viral budding via host ESCRT complex host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane RNA binding structural molecule activity zinc ion binding Human immunodeficiency virus type 1 group N AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Methylation Myristate Phosphoprotein Reference proteome Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucleoprotein Viral release from host cell Virion Zinc Zinc-finger MGARASVLTG MGARASVLTGGKLDQWESIYLRPGGKKKYRMKHLVWASRELERFACNPGLMDTADGCAKLLNQLEPALKTGSEELRSLYNALAVLYCVHSRIQIHNTQEALDKIKEKQEQHKPEPKNPEAGAAAATDSNISRNYPLVQTAQGQMVHQPLTPRTLNAWVKVIEEKAFSPEVIPMFMALSEGATPSDLNTMLNTVGGHQAAMQMLKEVINEEAADWDRTHPVPVGPLPPGQLRDPRGSDIAGTTSTLAEQVAWMTANPPVPVGDIYRRWIVLGLNRIVRMYSPVSILEIKQGPKEPFRDYVDRFYKTLRAEQATQEVKNWMTETLLVQNANPDCKQLLKALGPGATLEEMMTACQGVGGPAHKARVLAEAMSQVQQPTTSVFAQRGNFKGIRKPIKCFNCGKEGHLARNCKAPRRGGCWKCGQEGHQMKDCKNEGRQANFLGKSWSPFKGRPGNFPQTTTRKEPTAPPLESYGFQEEKSTQGKEMQENQERTENSLYPPLTSLRSLFGNDPSSQ |
DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by virus of host type I interferon-mediated signaling pathway | extracellular region; host cell cytoplasm; host cell nucleolus | actinin binding cyclin binding metal ion binding protein domain specific binding protein serine/threonine phosphatase inhibitor activity RNA-binding transcription regulator activity trans-activation response element binding | Human immunodeficiency virus type 1 group N | Acetylation Activator AIDS Alternative splicing Apoptosis Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Isopeptide bond Metal-binding Methylation Modulation of host chromatin by virus Modulation of host PP1 activity by virus Phosphoprotein Reference proteome RNA-binding Secreted Transcription Transcription regulation Ubl conjugation Viral immunoevasion Zinc | MEPVDPRLEP | MEPVDPRLEPWNHPGSQPKTACNNCYCKRCCYHCLYCFTKKGLGISYGRKKRSQRRRTPQSSKSHQDLIPEQPLSQQQGDQTGQKKQKEALESKTEADPCD | DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by virus of host type I interferon-mediated signaling pathway extracellular region; host cell cytoplasm; host cell nucleolus actinin binding cyclin binding metal ion binding protein domain specific binding protein serine/threonine phosphatase inhibitor activity RNA-binding transcription regulator activity trans-activation response element binding Human immunodeficiency virus type 1 group N Acetylation Activator AIDS Alternative splicing Apoptosis Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Isopeptide bond Metal-binding Methylation Modulation of host chromatin by virus Modulation of host PP1 activity by virus Phosphoprotein Reference proteome RNA-binding Secreted Transcription Transcription regulation Ubl conjugation Viral immunoevasion Zinc MEPVDPRLEP MEPVDPRLEPWNHPGSQPKTACNNCYCKRCCYHCLYCFTKKGLGISYGRKKRSQRRRTPQSSKSHQDLIPEQPLSQQQGDQTGQKKQKEALESKTEADPCD |
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral protein processing virion attachment to host cell virus-mediated perturbation of host defense response | host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane | structural molecule activity | Human immunodeficiency virus type 1 group N | AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Palmitate Reference proteome Signal Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Viral immunoevasion Viral penetration into host cytoplasm Virion Virus endocytosis by host Virus entry into host cell | MGMKSGWLLF | MGMKSGWLLFYLLVSLIKVIGSEQHWVTVYYGVPVWREAETTLFCASDAKAHSTEAHNIWATQACVPTDPNPQEVLLPNVTEKFNMWENKMADQMQEDIISLWEQSLKPCVKLTPLCVTMLCNDSYGEERNNTNMTTREPDIGYKQMKNCSFNATTELTDKKKQVYSLFYVEDVVPINAYNKTYRLINCNTTAVTQACPKTSFEPIPIHYCAPPGFAIMKCNEGNFSGNGSCTNVSTVQCTHGIKPVISTQLILNGSLNTDGIVIRNDSHSNLLVQWNETVPINCTRPGNNTGGQVQIGPAMTFYNIEKIVGDIRQAYCNVSKELWEPMWNRTREEIKKILGKNNITFRARERNEGDLEVTHLMFNCRGEFFYCNTSKLFNEELLNETGEPITLPCRIRQIVNLWTRVGKGIYAPPIRGVLNCTSNITGLVLEYSGGPDTKETIVYPSGGNMVNLWRQELYKYKVVSIEPIGVAPGKAKRRTVSREKRAAFGLGALFLGFLGAAGSTMGAASITLTVQARTLLSGIVQQQNILLRAIEAQQHLLQLSIWGIKQLQAKVLAIERYLRDQQILSLWGCSGKTICYTTVPWNETWSNNTSYDTIWNNLTWQQWDEKVRNYSGVIFGLIEQAQEQQNTNEKSLLELDQWDSLWSWFGITKWLWYIKIAIMIVAGIVGIRIISIVITIIARVRQGYSPLSLQTLIPTARGPDRPEETEGGVGEQDRGRSVRLVSGFSALVWEDLRNLLIFLYHRLTDSLLILRRTLELLGQSLSRGLQLLNELRTHLWGILAYWGKELRDSAISLLNTTAIVVAEGTDRIIELAQRIGRGILHIPRRIRQGLERALI | clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral protein processing virion attachment to host cell virus-mediated perturbation of host defense response host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane structural molecule activity Human immunodeficiency virus type 1 group N AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Palmitate Reference proteome Signal Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Viral immunoevasion Viral penetration into host cytoplasm Virion Virus endocytosis by host Virus entry into host cell MGMKSGWLLF MGMKSGWLLFYLLVSLIKVIGSEQHWVTVYYGVPVWREAETTLFCASDAKAHSTEAHNIWATQACVPTDPNPQEVLLPNVTEKFNMWENKMADQMQEDIISLWEQSLKPCVKLTPLCVTMLCNDSYGEERNNTNMTTREPDIGYKQMKNCSFNATTELTDKKKQVYSLFYVEDVVPINAYNKTYRLINCNTTAVTQACPKTSFEPIPIHYCAPPGFAIMKCNEGNFSGNGSCTNVSTVQCTHGIKPVISTQLILNGSLNTDGIVIRNDSHSNLLVQWNETVPINCTRPGNNTGGQVQIGPAMTFYNIEKIVGDIRQAYCNVSKELWEPMWNRTREEIKKILGKNNITFRARERNEGDLEVTHLMFNCRGEFFYCNTSKLFNEELLNETGEPITLPCRIRQIVNLWTRVGKGIYAPPIRGVLNCTSNITGLVLEYSGGPDTKETIVYPSGGNMVNLWRQELYKYKVVSIEPIGVAPGKAKRRTVSREKRAAFGLGALFLGFLGAAGSTMGAASITLTVQARTLLSGIVQQQNILLRAIEAQQHLLQLSIWGIKQLQAKVLAIERYLRDQQILSLWGCSGKTICYTTVPWNETWSNNTSYDTIWNNLTWQQWDEKVRNYSGVIFGLIEQAQEQQNTNEKSLLELDQWDSLWSWFGITKWLWYIKIAIMIVAGIVGIRIISIVITIIARVRQGYSPLSLQTLIPTARGPDRPEETEGGVGEQDRGRSVRLVSGFSALVWEDLRNLLIFLYHRLTDSLLILRRTLELLGQSLSRGLQLLNELRTHLWGILAYWGKELRDSAISLLNTTAIVVAEGTDRIIELAQRIGRGILHIPRRIRQGLERALI |
suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy | extracellular region; host cell Golgi membrane; host cell plasma membrane; membrane; virion component | GTP binding SH3 domain binding | Human immunodeficiency virus type 1 group N | AIDS Apoptosis Early protein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host autophagy by virus Inhibition of host MHC class I molecule presentation by virus Inhibition of host MHC class II molecule presentation by virus Lipoprotein Membrane Myristate Phosphoprotein Reference proteome Secreted SH3-binding Viral immunoevasion Virion Virulence | MGKIWSKSSL | MGKIWSKSSLVGWPEIRERMRRQTQEPAVEPAVGAGAASQDLANRGAITIRNTRDNNESIAWLEAQEEEEEVGFPVRPQVPLRPITYKQAFDLSFFLKDKGGLEGLVWSRKRQDILDLWMYHTQGILPDWHNYTPGPGIRYPVTFGWCFKLVPLSAEEVEEANEGDNNALLHPICQHGADDDHKEVLVWRFDSSLARRHVARELHPEFYKNC | suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy extracellular region; host cell Golgi membrane; host cell plasma membrane; membrane; virion component GTP binding SH3 domain binding Human immunodeficiency virus type 1 group N AIDS Apoptosis Early protein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host autophagy by virus Inhibition of host MHC class I molecule presentation by virus Inhibition of host MHC class II molecule presentation by virus Lipoprotein Membrane Myristate Phosphoprotein Reference proteome Secreted SH3-binding Viral immunoevasion Virion Virulence MGKIWSKSSL MGKIWSKSSLVGWPEIRERMRRQTQEPAVEPAVGAGAASQDLANRGAITIRNTRDNNESIAWLEAQEEEEEVGFPVRPQVPLRPITYKQAFDLSFFLKDKGGLEGLVWSRKRQDILDLWMYHTQGILPDWHNYTPGPGIRYPVTFGWCFKLVPLSAEEVEEANEGDNNALLHPICQHGADDDHKEVLVWRFDSSLARRHVARELHPEFYKNC |
microtubule-dependent intracellular transport of viral material towards nucleus viral entry into host cell viral penetration into host nucleus virus-mediated perturbation of host defense response | extracellular region; host cell cytoplasm; host cell nucleus; T=4 icosahedral viral capsid | DNA binding RNA binding structural molecule activity | Hepatitis B virus genotype A2 | Alternative initiation Disulfide bond Host nucleus Host-virus interaction Repeat Secreted Signal Viral immunoevasion | MQLFHLCLII | MQLFHLCLIISCTCPTVQASKLCLGWLWGMDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTASALYREALESPEHCSPHHTALRQAILCWVELMTLATWVGNNLQDPASRDLVVNYVNTNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRDRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC | microtubule-dependent intracellular transport of viral material towards nucleus viral entry into host cell viral penetration into host nucleus virus-mediated perturbation of host defense response extracellular region; host cell cytoplasm; host cell nucleus; T=4 icosahedral viral capsid DNA binding RNA binding structural molecule activity Hepatitis B virus genotype A2 Alternative initiation Disulfide bond Host nucleus Host-virus interaction Repeat Secreted Signal Viral immunoevasion MQLFHLCLII MQLFHLCLIISCTCPTVQASKLCLGWLWGMDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTASALYREALESPEHCSPHHTALRQAILCWVELMTLATWVGNNLQDPASRDLVVNYVNTNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRDRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC |
microtubule-dependent intracellular transport of viral material towards nucleus viral entry into host cell viral penetration into host nucleus virus-mediated perturbation of host defense response | extracellular region; host cell cytoplasm; host cell nucleus; T=4 icosahedral viral capsid | DNA binding RNA binding structural molecule activity | Hepatitis B virus genotype D | Alternative initiation Disulfide bond Host nucleus Host-virus interaction Repeat Secreted Signal Viral immunoevasion | MQLFHLCLII | MQLFHLCLIISCSCPTVQASKLCLGWLWDMDIDPYKEFGATVQLLSFLPHDFFPSVRDLLDTASALFRDALESPEHCSPHHTALRQAILCWGELMTLATWVGANLQDPASRELVVTYVNINMGLKFRQLLWFHISCLTFGRETVIEYLVSFGVWIRTPQAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC | microtubule-dependent intracellular transport of viral material towards nucleus viral entry into host cell viral penetration into host nucleus virus-mediated perturbation of host defense response extracellular region; host cell cytoplasm; host cell nucleus; T=4 icosahedral viral capsid DNA binding RNA binding structural molecule activity Hepatitis B virus genotype D Alternative initiation Disulfide bond Host nucleus Host-virus interaction Repeat Secreted Signal Viral immunoevasion MQLFHLCLII MQLFHLCLIISCSCPTVQASKLCLGWLWDMDIDPYKEFGATVQLLSFLPHDFFPSVRDLLDTASALFRDALESPEHCSPHHTALRQAILCWGELMTLATWVGANLQDPASRELVVTYVNINMGLKFRQLLWFHISCLTFGRETVIEYLVSFGVWIRTPQAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC |
proteolysis viral procapsid maturation | host cell nucleolus; host cell nucleoplasm; viral capsid | aspartic-type endopeptidase activity nucleic acid binding structural constituent of virion zinc ion binding | Rous sarcoma virus subgroup B | 3D-structure Aspartyl protease Capsid protein Host nucleus Hydrolase Metal-binding Protease Repeat Ribosomal frameshifting Viral capsid assembly Viral capsid maturation Viral matrix protein Viral release from host cell Virion Zinc Zinc-finger | MEAVIKVISS | MEAVIKVISSACKTYCGKTSPSKKEIGAMLSLLQKEGLLMSPSDLYSPGSWDPITAALSQRAMVLGKSGELKTWGLVLGALKAAREEQVTSEQAKFWLGLGGGRVSPPGPECIEKPATERRIDKGEEVGETTVQRDAKMAPEETATPKTVGTSCYHCGTAIGCNCATASAPPPPYVGSGLYPSLAGVGEQQGQGGDTPRGAEQPRAEPGHAGLAPGPALTDWARIREELASTGPPVVAMPVVIKTEGPAWTPLEPKLITRLADTVRTKGLRSPITMAEVEALMSSPLLPHDVTNLMRVILGPAPYALWMDAWGVQLQTVIAAATRDPRHPANGQGRGERTNLDRLKGLADGMVGNPQGQAALLRPGELVAITASALQAFREVARLAEPAGPWADITQGPSESFVDFANRLIKAVEGSDLPPSARAPVIIDCFRQKSQPDIQQLIRAAPSTLTTPGEIIKYVLDRQKIAPLTDQGIAAAMSSAIQPLVMAVVNRERDGQTGSGGRARRLCYTCGSPGHYQAQCPKKRKSGNSRERCQLCDGMGHNAKQCRRRDSNQGQRPGRGLSSGPWPVSEQPAVSLAMTMEHKDRPLVRVILTNTGSHPVKQRSVYITALLDSGADITIISEEDWPTDWPVVDTANPQIHGIGGGIPMRKSRDMIELGVINRDGSLERPLLLFPAVAMVRGSILGRDCLQGLGLRLTNL | proteolysis viral procapsid maturation host cell nucleolus; host cell nucleoplasm; viral capsid aspartic-type endopeptidase activity nucleic acid binding structural constituent of virion zinc ion binding Rous sarcoma virus subgroup B 3D-structure Aspartyl protease Capsid protein Host nucleus Hydrolase Metal-binding Protease Repeat Ribosomal frameshifting Viral capsid assembly Viral capsid maturation Viral matrix protein Viral release from host cell Virion Zinc Zinc-finger MEAVIKVISS MEAVIKVISSACKTYCGKTSPSKKEIGAMLSLLQKEGLLMSPSDLYSPGSWDPITAALSQRAMVLGKSGELKTWGLVLGALKAAREEQVTSEQAKFWLGLGGGRVSPPGPECIEKPATERRIDKGEEVGETTVQRDAKMAPEETATPKTVGTSCYHCGTAIGCNCATASAPPPPYVGSGLYPSLAGVGEQQGQGGDTPRGAEQPRAEPGHAGLAPGPALTDWARIREELASTGPPVVAMPVVIKTEGPAWTPLEPKLITRLADTVRTKGLRSPITMAEVEALMSSPLLPHDVTNLMRVILGPAPYALWMDAWGVQLQTVIAAATRDPRHPANGQGRGERTNLDRLKGLADGMVGNPQGQAALLRPGELVAITASALQAFREVARLAEPAGPWADITQGPSESFVDFANRLIKAVEGSDLPPSARAPVIIDCFRQKSQPDIQQLIRAAPSTLTTPGEIIKYVLDRQKIAPLTDQGIAAAMSSAIQPLVMAVVNRERDGQTGSGGRARRLCYTCGSPGHYQAQCPKKRKSGNSRERCQLCDGMGHNAKQCRRRDSNQGQRPGRGLSSGPWPVSEQPAVSLAMTMEHKDRPLVRVILTNTGSHPVKQRSVYITALLDSGADITIISEEDWPTDWPVVDTANPQIHGIGGGIPMRKSRDMIELGVINRDGSLERPLLLFPAVAMVRGSILGRDCLQGLGLRLTNL |
viral budding via host ESCRT complex | host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane | RNA binding structural molecule activity zinc ion binding | Human immunodeficiency virus type 1 group M subtype H | AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Methylation Myristate Phosphoprotein Reference proteome Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucleoprotein Viral release from host cell Virion Zinc Zinc-finger | MGARASVLSG | MGARASVLSGGKLDAWEKIRLRPGGKKKYRLKHLVWASRELERFALNPGLLETPEGCLQIIEQIQPAIKTGTEELKSLFNLVAVLYCVHRKIDVKDTKEALDKIEEIQNKSQQKTQQAAADKEKDNKVSQNYPIVQNAQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNAMLNTVGGHQAAMQMLKDTINEEAAEWDRVHPVHAGPIPPGQMREPRGSDIAGTTSTLQEQIAWMTGNPAIPVGDIYKRWIILGLNKIVRMYSPVSILDIKQGPKEPFRDYVDRFFKTLRAEQATQDVKNWMTETLLVQNANPDCKTILRALGQGASIEEMMTACQGVGGPSHKARVLAEAMSQVTNTNTAIMMQKGNFKGQRKFVKCFNCGKEGHIARNCRAPRKKGCWKCGREGHQMKDCTERQANFLGKIWPSSKGRPGNFLQSRPEPTAPPAESFGFGEEMTPSPKQEQLKDKEPPLASLRSLFGSDPLLQ | viral budding via host ESCRT complex host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane RNA binding structural molecule activity zinc ion binding Human immunodeficiency virus type 1 group M subtype H AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Methylation Myristate Phosphoprotein Reference proteome Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucleoprotein Viral release from host cell Virion Zinc Zinc-finger MGARASVLSG MGARASVLSGGKLDAWEKIRLRPGGKKKYRLKHLVWASRELERFALNPGLLETPEGCLQIIEQIQPAIKTGTEELKSLFNLVAVLYCVHRKIDVKDTKEALDKIEEIQNKSQQKTQQAAADKEKDNKVSQNYPIVQNAQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNAMLNTVGGHQAAMQMLKDTINEEAAEWDRVHPVHAGPIPPGQMREPRGSDIAGTTSTLQEQIAWMTGNPAIPVGDIYKRWIILGLNKIVRMYSPVSILDIKQGPKEPFRDYVDRFFKTLRAEQATQDVKNWMTETLLVQNANPDCKTILRALGQGASIEEMMTACQGVGGPSHKARVLAEAMSQVTNTNTAIMMQKGNFKGQRKFVKCFNCGKEGHIARNCRAPRKKGCWKCGREGHQMKDCTERQANFLGKIWPSSKGRPGNFLQSRPEPTAPPAESFGFGEEMTPSPKQEQLKDKEPPLASLRSLFGSDPLLQ |
cell migration embryo development ending in birth or egg hatching gastrulation kidney field specification mRNA stabilization negative regulation of nuclear-transcribed mRNA poly(A) tail shortening neurogenesis positive regulation of translation pronephros development response to cold response to UV stress granule assembly | cytoplasm; cytoplasmic stress granule; nucleoplasm; nucleus | enzyme binding mRNA 3'-UTR binding mRNA binding ribosome binding small ribosomal subunit rRNA binding translation repressor activity | Xenopus laevis | Alternative splicing Cytoplasm Developmental protein Direct protein sequencing Nucleus Reference proteome RNA-binding Stress response | MSDEGKLFIG | MSDEGKLFIGGLNFETNEDCLEQAFTKYGRISEVVVVKDRETKRSRGFGFVTFENVDDAKDAMMAMNGKSVDGRQIRVDQAGKSSGERRGGYRGGSSGGRGFFRGGRGRGGGDRGYGSSRFDNRSGGYGGSSGSRDYYGSGRSQGSYGDRSGGSYRDSYDSYATHE | cell migration embryo development ending in birth or egg hatching gastrulation kidney field specification mRNA stabilization negative regulation of nuclear-transcribed mRNA poly(A) tail shortening neurogenesis positive regulation of translation pronephros development response to cold response to UV stress granule assembly cytoplasm; cytoplasmic stress granule; nucleoplasm; nucleus enzyme binding mRNA 3'-UTR binding mRNA binding ribosome binding small ribosomal subunit rRNA binding translation repressor activity Xenopus laevis Alternative splicing Cytoplasm Developmental protein Direct protein sequencing Nucleus Reference proteome RNA-binding Stress response MSDEGKLFIG MSDEGKLFIGGLNFETNEDCLEQAFTKYGRISEVVVVKDRETKRSRGFGFVTFENVDDAKDAMMAMNGKSVDGRQIRVDQAGKSSGERRGGYRGGSSGGRGFFRGGRGRGGGDRGYGSSRFDNRSGGYGGSSGSRDYYGSGRSQGSYGDRSGGSYRDSYDSYATHE |
apoptotic process GTP metabolic process inner mitochondrial membrane organization membrane tubulation mitochondrial fusion negative regulation of apoptotic process visual perception | dendrite; mitochondrial crista; mitochondrial intermembrane space; mitochondrial outer membrane | cardiolipin binding GTP binding GTPase activity phosphatidic acid binding | Oncorhynchus masou | Apoptosis Coiled coil GTP-binding Hydrolase Lipid-binding Membrane Mitochondrion Mitochondrion inner membrane Nucleotide-binding Transit peptide Transmembrane Transmembrane helix | MLRVGRAVAC | MLRVGRAVACVACNNLASKNMGVRFRMPLQKLHPLSRAIHHRYNASANAQRPPHCSAARHFTSMSRLPMRPPKPSPGGHGGWRYQQHRSFWMLRLASRLLKLRYIVLGSAVGGGYTAKKTYEEWKDMLPDMSAYNWVIPDFVWELSDQIDLDKLTKILPELEEIAKLLPELPDFDKIGENFTFLKSILFTAEAPGDTPVKAATEAPVTATPEASDKQFKKSSDKEKVDQLQEELLRTQMKYQRMLERLEKENKDLRKVVLQKDEKGIHQRKIKKSLIDMYSEVLDILSDFDSNYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVAMFKDSSREFDLGKEEDLAALRHEIELRMRKSVKEGQTVSPETISLSVKGPGIQRMVLVDLPGVISTVTAGMAADTKETIFSISKNYMQNPNAIILCIQDGSVDAEADRHRPGQSNGPAGERTIFVLTKVDLAEKNLASPNRIQQIVEGKLFPMKALGYFAVVTGKGSAGESIDSIKDYEEDFFQNSRLLRDGMLKAHQVTTKNLSLAVSDCFWKMVRESVEQQADAFKASRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEAILQKKLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPHKALEVAWETLQEEFARFMAEYKGKDQDDIFDKLKEAVKDESIKRHKWNERAMDSLRVIQHNALEDRSITDKPQWDAAIQFMEETLQARLKDTDSVINDMVGPDWKQRWMSWKNRSPEQHTRNETRNELERLLKLHEDHTAYLANDEVTTVRKNLEGRGVEVDPALIKDTWHQLYRRHFLQKALQHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLLITANTLRQQLTNTEVRRLEKNVKEVLEDFGEDNERKVHLITGRRVQLAEDLKKVREIQEKLEAFIEALHKEK | apoptotic process GTP metabolic process inner mitochondrial membrane organization membrane tubulation mitochondrial fusion negative regulation of apoptotic process visual perception dendrite; mitochondrial crista; mitochondrial intermembrane space; mitochondrial outer membrane cardiolipin binding GTP binding GTPase activity phosphatidic acid binding Oncorhynchus masou Apoptosis Coiled coil GTP-binding Hydrolase Lipid-binding Membrane Mitochondrion Mitochondrion inner membrane Nucleotide-binding Transit peptide Transmembrane Transmembrane helix MLRVGRAVAC MLRVGRAVACVACNNLASKNMGVRFRMPLQKLHPLSRAIHHRYNASANAQRPPHCSAARHFTSMSRLPMRPPKPSPGGHGGWRYQQHRSFWMLRLASRLLKLRYIVLGSAVGGGYTAKKTYEEWKDMLPDMSAYNWVIPDFVWELSDQIDLDKLTKILPELEEIAKLLPELPDFDKIGENFTFLKSILFTAEAPGDTPVKAATEAPVTATPEASDKQFKKSSDKEKVDQLQEELLRTQMKYQRMLERLEKENKDLRKVVLQKDEKGIHQRKIKKSLIDMYSEVLDILSDFDSNYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVAMFKDSSREFDLGKEEDLAALRHEIELRMRKSVKEGQTVSPETISLSVKGPGIQRMVLVDLPGVISTVTAGMAADTKETIFSISKNYMQNPNAIILCIQDGSVDAEADRHRPGQSNGPAGERTIFVLTKVDLAEKNLASPNRIQQIVEGKLFPMKALGYFAVVTGKGSAGESIDSIKDYEEDFFQNSRLLRDGMLKAHQVTTKNLSLAVSDCFWKMVRESVEQQADAFKASRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEAILQKKLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPHKALEVAWETLQEEFARFMAEYKGKDQDDIFDKLKEAVKDESIKRHKWNERAMDSLRVIQHNALEDRSITDKPQWDAAIQFMEETLQARLKDTDSVINDMVGPDWKQRWMSWKNRSPEQHTRNETRNELERLLKLHEDHTAYLANDEVTTVRKNLEGRGVEVDPALIKDTWHQLYRRHFLQKALQHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLLITANTLRQQLTNTEVRRLEKNVKEVLEDFGEDNERKVHLITGRRVQLAEDLKKVREIQEKLEAFIEALHKEK |
cellular response to gamma radiation DNA recombination double-strand break repair via nonhomologous end joining negative regulation of DNA-templated transcription telomere maintenance | chromosome; Ku70:Ku80 complex; nonhomologous end joining complex; nucleoplasm; ribonucleoprotein complex | 5'-deoxyribose-5-phosphate lyase activity ATP binding damaged DNA binding DNA helicase activity hydrolase activity RNA binding telomeric DNA binding | Gallus gallus | Activator ATP-binding Chromosome DNA damage DNA recombination DNA repair DNA-binding Helicase Hydrolase Lyase Multifunctional enzyme Nucleotide-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MEMWVLGEVG | MEMWVLGEVGMAVLSAAAMADWVSYYRGDGPDEEEDGEQQEEEGPEAVADYRFSGRDSLIFLVDASKAMFEPYENEEAATPFDMTMQCIRNVYTSKIISSDKDLLSVVFYGMENNKNSADFKHIYVLQELDNPGAKRILELDQYRGDEGRVLFRETFGHNADYSLGEALWACSNLFSDVRVRLSHKRIMLFTNEDNPHANDSAKAKLARTRAGDLRDTGIILDLMHLKKPGGFDISLFYRDIINVAEDEDLGIQPDESGKLEHLMKKVRAKETRKRALSRLNLYLNKDLSFSVGVYNLIQKAYKPYPVKLYRETNEPVKTKTRVFNGKTGSLLLPSDTKRAQTYGNRQIAMEKEETEEVKRFDSPGLFLIGFKPLSMLKQHHHIRPSQFMYPEESLVTGSTTLFNALLMKCLEKEVMALCRYIARRNTPPRIVALIPQEEEVDEQKVQIAPPGFHIIFLPYADDKRNVDFTEKVPANREQVDKMKGIIQKLRFKYRTDSFENPVLQQHFRNLEALALDMLEPEQAEDLTMPKTEEMSRRLGNLVEEFKQLVYPPDYSPEGKAAKRKQAGDAQAEKRPKIEISEDSLRSYVQNGTLGKLTVSALKDTCRHYGLRSGGKKQELIDALTEYFSGR | cellular response to gamma radiation DNA recombination double-strand break repair via nonhomologous end joining negative regulation of DNA-templated transcription telomere maintenance chromosome; Ku70:Ku80 complex; nonhomologous end joining complex; nucleoplasm; ribonucleoprotein complex 5'-deoxyribose-5-phosphate lyase activity ATP binding damaged DNA binding DNA helicase activity hydrolase activity RNA binding telomeric DNA binding Gallus gallus Activator ATP-binding Chromosome DNA damage DNA recombination DNA repair DNA-binding Helicase Hydrolase Lyase Multifunctional enzyme Nucleotide-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation MEMWVLGEVG MEMWVLGEVGMAVLSAAAMADWVSYYRGDGPDEEEDGEQQEEEGPEAVADYRFSGRDSLIFLVDASKAMFEPYENEEAATPFDMTMQCIRNVYTSKIISSDKDLLSVVFYGMENNKNSADFKHIYVLQELDNPGAKRILELDQYRGDEGRVLFRETFGHNADYSLGEALWACSNLFSDVRVRLSHKRIMLFTNEDNPHANDSAKAKLARTRAGDLRDTGIILDLMHLKKPGGFDISLFYRDIINVAEDEDLGIQPDESGKLEHLMKKVRAKETRKRALSRLNLYLNKDLSFSVGVYNLIQKAYKPYPVKLYRETNEPVKTKTRVFNGKTGSLLLPSDTKRAQTYGNRQIAMEKEETEEVKRFDSPGLFLIGFKPLSMLKQHHHIRPSQFMYPEESLVTGSTTLFNALLMKCLEKEVMALCRYIARRNTPPRIVALIPQEEEVDEQKVQIAPPGFHIIFLPYADDKRNVDFTEKVPANREQVDKMKGIIQKLRFKYRTDSFENPVLQQHFRNLEALALDMLEPEQAEDLTMPKTEEMSRRLGNLVEEFKQLVYPPDYSPEGKAAKRKQAGDAQAEKRPKIEISEDSLRSYVQNGTLGKLTVSALKDTCRHYGLRSGGKKQELIDALTEYFSGR |
canonical Wnt signaling pathway positive regulation of DNA-binding transcription factor activity | plasma membrane | G protein-coupled receptor activity | Xenopus laevis | Cell membrane Developmental protein Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Signal Transducer Transmembrane Transmembrane helix Wnt signaling pathway | MESLSLSLLL | MESLSLSLLLLVSWLQGSQCAAAKELSCQEITVPLCKDIGYNYTYMPNQFNHDTQDEAGMEVHQFWPLVVIHCSPDLKFFLCSMYTPICLEDYKKPLPPCRSVCERARAGCAPLMRQYGFAWPDRMRCDRLPEQGNPDTLCMDYYNRTEQTTAAPSHPEPPKPPARSVPKGRTRVEPPRSRSRATGCESGCQCRAPMVQVSNERHPLYNRVRTGQIPNCAMPCHNPFFSPEERTFTEFWIGLWSVLCFASTFATVSTFLIDMERFKYPERPIIFLSACYLLVSTGYLIRLIAGHEKVACSRGELDLEHIIHYETTGPALCTLVFLLIYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYSQYFHLAAWLVPSIKSIAVLALSSVDGDPVAGICFVGNQNLDNLRGFVLAPLVIYLFIGSMFLLAGFVSLFRIRSVIKQGGTKTDKLEKLMIRIGIFSVLYTVPATIVVACFFYEQHNRQGWEVAHNCNSCQPEMAQPHRPDYAVFMLKYFMCLVVGITSGVWIWSGKTLESWRAFCTRCCWGSKATGGSMYSDVSTGLTWRSGTGSSVSCPKQMPLSQV | canonical Wnt signaling pathway positive regulation of DNA-binding transcription factor activity plasma membrane G protein-coupled receptor activity Xenopus laevis Cell membrane Developmental protein Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Signal Transducer Transmembrane Transmembrane helix Wnt signaling pathway MESLSLSLLL MESLSLSLLLLVSWLQGSQCAAAKELSCQEITVPLCKDIGYNYTYMPNQFNHDTQDEAGMEVHQFWPLVVIHCSPDLKFFLCSMYTPICLEDYKKPLPPCRSVCERARAGCAPLMRQYGFAWPDRMRCDRLPEQGNPDTLCMDYYNRTEQTTAAPSHPEPPKPPARSVPKGRTRVEPPRSRSRATGCESGCQCRAPMVQVSNERHPLYNRVRTGQIPNCAMPCHNPFFSPEERTFTEFWIGLWSVLCFASTFATVSTFLIDMERFKYPERPIIFLSACYLLVSTGYLIRLIAGHEKVACSRGELDLEHIIHYETTGPALCTLVFLLIYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYSQYFHLAAWLVPSIKSIAVLALSSVDGDPVAGICFVGNQNLDNLRGFVLAPLVIYLFIGSMFLLAGFVSLFRIRSVIKQGGTKTDKLEKLMIRIGIFSVLYTVPATIVVACFFYEQHNRQGWEVAHNCNSCQPEMAQPHRPDYAVFMLKYFMCLVVGITSGVWIWSGKTLESWRAFCTRCCWGSKATGGSMYSDVSTGLTWRSGTGSSVSCPKQMPLSQV |
nucleosome assembly regulation of NAD metabolic process | nucleosome; nucleus | ADP-D-ribose binding ADP-D-ribose modification-dependent protein binding DNA binding protein heterodimerization activity structural constituent of chromatin | Gallus gallus | Acetylation ADP-ribosylation Alternative splicing Chromatin regulator Chromosome DNA-binding Isopeptide bond Methylation Nucleosome core Nucleus Phosphoprotein Reference proteome Ubl conjugation | MSSRGGKKKS | MSSRGGKKKSTKTSRSAKAGVIFPVGRMLRYIKKGHPKYRIGVGAPVYMAAVLEYLTAEILELAGNAARDNKKGRVTPRHILLAVANDEELNQLLKGVTIASGGVLPNIHPELLAKKRGSKGKLEAIITPPPAKKAKSPSQKKTVSKKTGGKKGARKSKKKQGEVSKSASADSTTEGTPADGFTVLSTKSLFLGQKLQVVQADIATIDSDAVVHPTNSDFYTGGEVGSTLEKKGGKEFVEAVIELRKKNGPLDIAGAVVSAGHGLPAKFVIHCNSPGWGSDKCEELLEKTVKNCLALADEKKLKSIAFPSIGSGRNGFPKQTAAQLILKAISSYFVSTMSSSIKTVYFVLFDSESIGIYVQEMAKLDAN | nucleosome assembly regulation of NAD metabolic process nucleosome; nucleus ADP-D-ribose binding ADP-D-ribose modification-dependent protein binding DNA binding protein heterodimerization activity structural constituent of chromatin Gallus gallus Acetylation ADP-ribosylation Alternative splicing Chromatin regulator Chromosome DNA-binding Isopeptide bond Methylation Nucleosome core Nucleus Phosphoprotein Reference proteome Ubl conjugation MSSRGGKKKS MSSRGGKKKSTKTSRSAKAGVIFPVGRMLRYIKKGHPKYRIGVGAPVYMAAVLEYLTAEILELAGNAARDNKKGRVTPRHILLAVANDEELNQLLKGVTIASGGVLPNIHPELLAKKRGSKGKLEAIITPPPAKKAKSPSQKKTVSKKTGGKKGARKSKKKQGEVSKSASADSTTEGTPADGFTVLSTKSLFLGQKLQVVQADIATIDSDAVVHPTNSDFYTGGEVGSTLEKKGGKEFVEAVIELRKKNGPLDIAGAVVSAGHGLPAKFVIHCNSPGWGSDKCEELLEKTVKNCLALADEKKLKSIAFPSIGSGRNGFPKQTAAQLILKAISSYFVSTMSSSIKTVYFVLFDSESIGIYVQEMAKLDAN |
heart looping heart morphogenesis positive regulation of gene expression protein homotetramerization response to retinoic acid retinoic acid biosynthetic process retinoic acid metabolic process retinol metabolic process spinal cord motor neuron differentiation | cytoplasm | aldehyde dehydrogenase (NAD+) activity NAD-retinol dehydrogenase activity retinal dehydrogenase activity | Gallus gallus | Cytoplasm Lipid metabolism NAD Oxidoreductase Reference proteome | MTSSKIEMPG | MTSSKIEMPGEVKADPAALMASLHLLPSPTLNLEIKHTKIFINNEWQNSESGRVFPVYNPATGEQICEIQEADKVDTDKAVRAARLAFSLGSVWRRMDASERGQLLDKLADLVERDRAVLATMESLNSGKPFLQAFYVDLQGVIKTLRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVVNILPGFGPIVGAAIASHVGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIYVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGITEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTVDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGESGLREYSEVKTVTIKIPQKNS | heart looping heart morphogenesis positive regulation of gene expression protein homotetramerization response to retinoic acid retinoic acid biosynthetic process retinoic acid metabolic process retinol metabolic process spinal cord motor neuron differentiation cytoplasm aldehyde dehydrogenase (NAD+) activity NAD-retinol dehydrogenase activity retinal dehydrogenase activity Gallus gallus Cytoplasm Lipid metabolism NAD Oxidoreductase Reference proteome MTSSKIEMPG MTSSKIEMPGEVKADPAALMASLHLLPSPTLNLEIKHTKIFINNEWQNSESGRVFPVYNPATGEQICEIQEADKVDTDKAVRAARLAFSLGSVWRRMDASERGQLLDKLADLVERDRAVLATMESLNSGKPFLQAFYVDLQGVIKTLRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVVNILPGFGPIVGAAIASHVGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIYVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGITEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTVDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGESGLREYSEVKTVTIKIPQKNS |
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