Biological Process
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Cellular Component
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Molecular Function
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Organism
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Keywords
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Sequence 10
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Sequence
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3.91k
regulation of sensory perception of pain
extracellular exosome; extracellular space
endopeptidase inhibitor activity
Homo sapiens
Direct protein sequencing Pyrrolidone carboxylic acid Reference proteome Repeat Secreted Signal
MKSLTWILGL
MKSLTWILGLWALAACFTPGESQRGPRGPYPPGPLAPPQPFGPGFVPPPPPPPYGPGRIPPPPPAPYGPGIFPPPPPQP
regulation of sensory perception of pain extracellular exosome; extracellular space endopeptidase inhibitor activity Homo sapiens Direct protein sequencing Pyrrolidone carboxylic acid Reference proteome Repeat Secreted Signal MKSLTWILGL MKSLTWILGLWALAACFTPGESQRGPRGPYPPGPLAPPQPFGPGFVPPPPPPPYGPGRIPPPPPAPYGPGIFPPPPPQP
chondrocyte differentiation enamel mineralization epithelial to mesenchymal transition osteoblast differentiation positive regulation of collagen biosynthetic process
collagen-containing extracellular matrix; extracellular region
structural constituent of tooth enamel
Bos taurus
Alternative splicing Biomineralization Direct protein sequencing Extracellular matrix Phosphoprotein Reference proteome Repeat Secreted Signal
MGTWILFACL
MGTWILFACLLGAAFSMPLPPHPGHPGYINFSYEVLTPLKWYQSMIRHPYPSYGYEPMGGWLHHQIIPVVSQQTPQNHALQPHHHIPMVPAQQPVVPQQPMMPVPGQHSMTPTQHHQPNLPLPAQQPFQPQSIQPQPHQPLQPHQPLQPMQPMQPLQPLQPLQPQPPVHPIQPLPPQPPLPPIFPMQPLPPMLPDLPLEAWPATDKTKREEVD
chondrocyte differentiation enamel mineralization epithelial to mesenchymal transition osteoblast differentiation positive regulation of collagen biosynthetic process collagen-containing extracellular matrix; extracellular region structural constituent of tooth enamel Bos taurus Alternative splicing Biomineralization D...
biomineral tissue development bone development brain development cellular response to insulin stimulus cognition glucose homeostasis learning or memory negative regulation of bone development positive regulation of neurotransmitter secretion regulation of bone mineralization regulation of cellular response to insulin s...
cytoplasm; extracellular region
calcium ion binding hormone activity structural constituent of bone
Macaca fascicularis
Biomineralization Calcium Direct protein sequencing Disulfide bond Gamma-carboxyglutamic acid Hormone Hydroxylation Metal-binding Reference proteome Secreted
YLYQWLGAPA
YLYQWLGAPAPYPDPLEPKREVCELNPDCDELADHIGFQEAYRRFYGPV
biomineral tissue development bone development brain development cellular response to insulin stimulus cognition glucose homeostasis learning or memory negative regulation of bone development positive regulation of neurotransmitter secretion regulation of bone mineralization regulation of cellular response to insulin s...
biomineral tissue development bone development brain development cellular response to insulin stimulus cognition glucose homeostasis learning or memory negative regulation of bone development osteoblast differentiation positive regulation of neurotransmitter secretion regulation of bone mineralization regulation of cel...
cytoplasm; extracellular region
calcium ion binding hormone activity hydroxyapatite binding structural constituent of bone
Bos taurus
3D-structure Biomineralization Calcium Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Gamma-carboxyglutamic acid Hormone Hydroxylation Metal-binding Reference proteome Secreted Signal
MRTPMLLALL
MRTPMLLALLALATLCLAGRADAKPGDAESGKGAAFVSKQEGSEVVKRLRRYLDHWLGAPAPYPDPLEPKREVCELNPDCDELADHIGFQEAYRRFYGPV
biomineral tissue development bone development brain development cellular response to insulin stimulus cognition glucose homeostasis learning or memory negative regulation of bone development osteoblast differentiation positive regulation of neurotransmitter secretion regulation of bone mineralization regulation of cel...
biomineral tissue development bone development brain development cellular response to insulin stimulus cognition glucose homeostasis learning or memory negative regulation of bone development osteoblast differentiation positive regulation of neurotransmitter secretion regulation of bone mineralization regulation of cel...
cytoplasm; extracellular region
calcium ion binding hormone activity hydroxyapatite binding structural constituent of bone
Felis catus
Biomineralization Calcium Direct protein sequencing Disulfide bond Gamma-carboxyglutamic acid Hormone Hydroxylation Metal-binding Reference proteome Secreted
YLAPGLGAPA
YLAPGLGAPAPYPDPLEPKREICELNPDCDELADHIGFQDAYRRFYGTV
biomineral tissue development bone development brain development cellular response to insulin stimulus cognition glucose homeostasis learning or memory negative regulation of bone development osteoblast differentiation positive regulation of neurotransmitter secretion regulation of bone mineralization regulation of cel...
biomineral tissue development bone development cellular response to insulin stimulus glucose homeostasis negative regulation of bone development osteoblast differentiation regulation of bone mineralization regulation of cellular response to insulin stimulus response to vitamin K type B pancreatic cell proliferation
extracellular region
calcium ion binding hormone activity hydroxyapatite binding structural constituent of bone
Gallus gallus
Biomineralization Calcium Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Gamma-carboxyglutamic acid Hormone Metal-binding Reference proteome Secreted Signal
MKAAALLLLA
MKAAALLLLAALLTFSLCRSAPDGSDARSAKAFISHRQRAEMVRRQKRHYAQDSGVAGAPPNPLEAQREVCELSPDCDELADQIGFQEAYRRFYGPV
biomineral tissue development bone development cellular response to insulin stimulus glucose homeostasis negative regulation of bone development osteoblast differentiation regulation of bone mineralization regulation of cellular response to insulin stimulus response to vitamin K type B pancreatic cell proliferation ext...
cellular response to heat centrosome cycle cold acclimation membrane bending multivesicular body fusion to apical plasma membrane negative regulation of cell population proliferation oogenesis pole plasm mRNA localization positive regulation of insulin receptor signaling pathway positive regulation of neuroblast prolif...
centrosome; cytoplasm; cytosol; endoplasmic reticulum chaperone complex; perinuclear region of cytoplasm; plasma membrane; polytene chromosome interband; protein folding chaperone complex; protein-containing complex
ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone disordered domain specific binding insulin receptor binding TPR domain binding unfolded protein binding
Drosophila melanogaster
ATP-binding Chaperone Cytoplasm Nucleotide-binding Phosphoprotein Reference proteome Stress response
MPEEAETFAF
MPEEAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELYIKLIPNKTAGTLTIIDTGIGMTKSDLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVADKVTVTSKNNDDEQYVWESSAGGSFTVRADNSEPLGRGTKIVLYIKEDQTDYLEESKIKEIVNKHSQFIGYPIKLLVEKEREKEVSDDEADDEKKEGDEKKEMETDEPKIEDVGEDEDADKKDKDAKKKKTIKEKYTEDEELNKTKPIWTRNPDDISQEEYGEFYKSLTNDWEDHLAVKHFSVEGQL...
cellular response to heat centrosome cycle cold acclimation membrane bending multivesicular body fusion to apical plasma membrane negative regulation of cell population proliferation oogenesis pole plasm mRNA localization positive regulation of insulin receptor signaling pathway positive regulation of neuroblast prolif...
de novo' protein folding box C/D snoRNP assembly cellular response to heat positive regulation of telomere maintenance via telomerase proteasome assembly protein folding protein maturation protein refolding protein stabilization protein targeting to mitochondrion regulation of telomere maintenance response to osmotic s...
cytoplasm; cytosol; nucleus; perinuclear region of cytoplasm; plasma membrane; protein-containing complex
ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone identical protein binding unfolded protein binding
Saccharomyces cerevisiae
3D-structure ATP-binding Chaperone Cytoplasm Nucleotide-binding Phosphoprotein Reference proteome Repeat Stress response
MASETFEFQA
MASETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYKSLSDPKQLETEPDLFIRITPKPEQKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVGFYSLFLVADRVQVISKSNDDEQYIWESNAGGSFTVTLDEVNERIGRGTILRLFLKDDQLEYLEEKRIKEVIKRHSEFVAYPIQLVVTKEVEKEVPIPEEEKKDEEKKDEEKKDEDDKKPKLEEVDEEEEKKPKTKKVKEEVQEIEELNKTKPLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAI...
de novo' protein folding box C/D snoRNP assembly cellular response to heat positive regulation of telomere maintenance via telomerase proteasome assembly protein folding protein maturation protein refolding protein stabilization protein targeting to mitochondrion regulation of telomere maintenance response to osmotic s...
angiogenesis anterior/posterior pattern specification embryonic skeletal system morphogenesis negative regulation of cell-matrix adhesion negative regulation of DNA-templated transcription negative regulation of keratinocyte differentiation negative regulation of leukocyte migration negative regulation of monocyte diff...
nuclear membrane; nucleoplasm; nucleus
DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-spe...
Mus musculus
Developmental protein DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation
MSSSYYVNAL
MSSSYYVNALFSKYTAGASLFQNAEPTSCSFAPNSQRSGYGPGAGAFASTVPGLYNVNSPLYQSPFASGYGLGADAYNLPCASYDQNIPGLCSDLAKGACDKADEGVLHGPAEASFRIYPWMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKDESQAPTAAPEDAVPSVSTAADKADEEEEEEEEEEEEEEE
angiogenesis anterior/posterior pattern specification embryonic skeletal system morphogenesis negative regulation of cell-matrix adhesion negative regulation of DNA-templated transcription negative regulation of keratinocyte differentiation negative regulation of leukocyte migration negative regulation of monocyte diff...
angiogenesis animal organ formation animal organ morphogenesis anterior/posterior pattern specification blood vessel remodeling cartilage development cell population proliferation embryonic skeletal system development embryonic skeletal system morphogenesis gene expression glossopharyngeal nerve morphogenesis parathyro...
nucleoplasm; nucleus
DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific HMG box domain binding RNA polymerase II cis-regulatory region sequence-specific DNA binding
Mus musculus
Developmental protein DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation
MQKATYYDSS
MQKATYYDSSAIYGGYPYQAANGFAYNASQQPYAPSAALGTDGVEYHRPACSLQSPASAGGHPKTHELSEACLRTLSGPPSQPPGLGEPPLPPPPPQAAPPAPQPPQPPPQPPAPTPAAPPPPSSVSPPQSANSNPTPASTAKSPLLNSPTVGKQIFPWMKESRQNTKQKTSGSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKPPQGAYGLPPASYPAPLPSC...
angiogenesis animal organ formation animal organ morphogenesis anterior/posterior pattern specification blood vessel remodeling cartilage development cell population proliferation embryonic skeletal system development embryonic skeletal system morphogenesis gene expression glossopharyngeal nerve morphogenesis parathyro...
anterior/posterior axis specification anterior/posterior pattern specification heart development lymph gland development midgut development muscle cell fate specification negative regulation of transcription by RNA polymerase II neuroblast development positive regulation of transcription by RNA polymerase II regulation...
cytoplasm; nucleus
DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding
Drosophila melanogaster
3D-structure Alternative splicing Developmental protein DNA-binding Homeobox Nucleus Reference proteome Repeat
MTMSTNNCES
MTMSTNNCESMTSYFTNSYMGADMHHGHYPGNGVTDLDAQQMHHYSQNANHQGNMPYPRFPPYDRMPYYNGQGMDQQQQHQVYSRPDSPSSQVGGVMPQAQTNGQLGVPQQQQQQQQQPSQNQQQQQAQQAPQQLQQQLPQVTQQVTHPQQQQQQPVVYASCKLQAAVGGLGMVPEGGSPPLVDQMSGHHMNAQMTLPHHMGHPQAQLGYTDVGVPDVTEVHQNHHNMGMYQQQSGVPPVGAPPQGMMHQGQGPPQMHQGHPGQHTPPSQNPNSQSSGMPSPLYPWMRSQFGKCQERKRGRQTYTRYQTLELEKEFHFNR...
anterior/posterior axis specification anterior/posterior pattern specification heart development lymph gland development midgut development muscle cell fate specification negative regulation of transcription by RNA polymerase II neuroblast development positive regulation of transcription by RNA polymerase II regulation...
anterior/posterior pattern specification cell fate specification central nervous system development germ cell migration gonadal mesoderm development negative regulation of transcription by RNA polymerase II periodic partitioning by pair rule gene positive regulation of transcription by RNA polymerase II regulation of D...
nucleus
DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding
Drosophila melanogaster
3D-structure Developmental protein DNA-binding Homeobox Nucleus Pair-rule protein Phosphoprotein Reference proteome Transcription Transcription regulation
MATTNSQSHY
MATTNSQSHYSYADNMNMYNMYHPHSLPPTYYDNSGSNAYYQNTSNYQGYYPQESYSESCYYYNNQEQVTTQTVPPVQPTTPPPKATKRKAEDDAASIIAAVEERPSTLRALLTNPVKKLKYTPDYFYTTVEQVKKAPAVSTKVTASPAPSYDQEYVTVPTPSASEDVDYLDVYSPQSQTQKLKNGDFATPPPTTPTSLPPLEGISTPPQSPGEKSSSAVSQEINHRIVTAPNGAGDFNWSHIEETLASDCKDSKRTRQTYTRYQTLELEKEFHFNRYITRRRRIDIANALSLSERQIKIWFQNRRMKSKKDRTLDSSPE...
anterior/posterior pattern specification cell fate specification central nervous system development germ cell migration gonadal mesoderm development negative regulation of transcription by RNA polymerase II periodic partitioning by pair rule gene positive regulation of transcription by RNA polymerase II regulation of D...
analia development anterior head segmentation anterior/posterior lineage restriction, imaginal disc axon guidance compartment pattern specification genital disc anterior/posterior pattern formation genital disc development gonad development imaginal disc-derived wing vein specification negative regulation of gene expre...
nucleus
DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific DNA bindi...
Drosophila melanogaster
3D-structure Developmental protein DNA-binding Homeobox Nucleus Phosphoprotein Reference proteome Repressor Segmentation polarity protein Transcription Transcription regulation
MALEDRCSPQ
MALEDRCSPQSAPSPITLQMQHLHHQQQQQQQQQQQMQHLHQLQQLQQLHQQQLAAGVFHHPAMAFDAAAAAAAAAAAAAAHAHAAALQQRLSGSGSPASCSTPASSTPLTIKEEESDSVIGDMSFHNQTHTTNEEEEAEEDDDIDVDVDDTSAGGRLPPPAHQQQSTAKPSLAFSISNILSDRFGDVQKPGKSMENQASIFRPFEASRSQTATPSAFTRVDLLEFSRQQQAAAAAATAAMMLERANFLNCFNPAAYPRIHEEIVQSRLRRSAANAVIPPPMSSKMSDANPEKSALGSLCKAVSQIGQPAAPTMTQPPLS...
analia development anterior head segmentation anterior/posterior lineage restriction, imaginal disc axon guidance compartment pattern specification genital disc anterior/posterior pattern formation genital disc development gonad development imaginal disc-derived wing vein specification negative regulation of gene expre...
lipid catabolic process sex differentiation
extracellular region; extracellular space; vesicle
serine hydrolase activity
Drosophila melanogaster
Phosphoprotein Reference proteome Secreted Signal Sulfation
MNPMRVLSLL
MNPMRVLSLLACLAVAALAKPNGRMDNSVNQALKPSQWLSGSQLEAIPALDDFTIERLENMNLERGAELLQQVYHLSQIHHNVEPNYVPSGIQVYVPKPNGDKTVAPLNEMIQRLKQKQNFGEDEVTIIVTGLPQTSETVKKATRKLVQAYMQRYNLQQQRQHGKNGNQDYQDQSNEQRKNQRTSSEEDYSEEVKNAKTQSGDIIVIDLGSKLNTYERYAMLDIEKTGAKIGKWIVQMVNELDMPFDTIHLIGQNVGAHVAGAAAQEFTRLTGHKLRRVTGLDPSKIVAKSKNTLTGLARGDAEFVDAIHTSVYGMGTPI...
lipid catabolic process sex differentiation extracellular region; extracellular space; vesicle serine hydrolase activity Drosophila melanogaster Phosphoprotein Reference proteome Secreted Signal Sulfation MNPMRVLSLL MNPMRVLSLLACLAVAALAKPNGRMDNSVNQALKPSQWLSGSQLEAIPALDDFTIERLENMNLERGAELLQQVYHLSQIHHNVEPNYVPSGIQVYVPKPNGDKT...
lipid catabolic process sex differentiation
extracellular region; extracellular space
serine hydrolase activity
Drosophila melanogaster
Direct protein sequencing Phosphoprotein Reference proteome Secreted Signal Sulfation
MNPLRTLCVM
MNPLRTLCVMACLLAVAMGNPQSGNRSGRRSNSLDNVEQPSNWVNPREVEELPNLKEVTLKKLQEMSLEEGATLLDKLYHLSQFNHVFKPDYTPEPSQIRGYIVGERGQKIEFNLNTLVEKVKRQQKFGDDEVTIFIQGLPETNTQVQKATRKLVQAYQQRYNLQPYETTDYSNEEQSQRSSSEEQQTQRRKQNGEQDDTKTGDLIVIQLGNAIEDFEQYATLNIERLGEIIGNRLVELTNTVNVPQEIIHLIGSGPAAHVAGVAGRQFTRQTGHKLRRITALDPTKIYGKPEERLTGLARGDADFVDAIHTSAYGMGTS...
lipid catabolic process sex differentiation extracellular region; extracellular space serine hydrolase activity Drosophila melanogaster Direct protein sequencing Phosphoprotein Reference proteome Secreted Signal Sulfation MNPLRTLCVM MNPLRTLCVMACLLAVAMGNPQSGNRSGRRSNSLDNVEQPSNWVNPREVEELPNLKEVTLKKLQEMSLEEGATLLDKLYHLSQFNHV...
asexual reproduction cell adhesion cell-cell adhesion cell-substrate adhesion cortical cytoskeleton organization cytoskeleton organization lectin-induced modified bacterial internalization mitotic cytokinesis protein localization to cell cortex regulation of gene expression regulation of protein complex stability respo...
cell cortex; cell surface; cytoplasm; cytosol; extracellular matrix; intracellular vesicle; phagocytic vesicle; protein complex involved in cell adhesion; symbiont cell surface
carbohydrate binding lipooligosaccharide binding N-acetylgalactosamine binding oligosaccharide binding polysaccharide binding
Dictyostelium discoideum
3D-structure Acetylation Cell adhesion Cytoplasm Lectin Reference proteome
MSTQGLVQLL
MSTQGLVQLLANAQCHLRTSTNYNGVHTQFNSALNYKNNGTNTIDGSEAWCSSIVDTNQYIVAGCEVPRTFMCVALQGRGDADQWVTSYKIRYSLDNVSWFEYRNGAAVTGVTDRNTVVNHFFDTPIRARSIAIHPLTWNGHISLRCEFYTQPVQSSVTQVGADIYTGDNCALNTGSGKREVVVPVKFQFEFATLPKVALNFDQIDCTDATNQTRIGVQPRNITTKGFDCVFYTWNENKVYSLRADYIATALE
asexual reproduction cell adhesion cell-cell adhesion cell-substrate adhesion cortical cytoskeleton organization cytoskeleton organization lectin-induced modified bacterial internalization mitotic cytokinesis protein localization to cell cortex regulation of gene expression regulation of protein complex stability respo...
cell adhesion cell-cell adhesion cytoskeleton organization response to cAMP response to folic acid
cell surface; cytoplasm; extracellular matrix; protein complex involved in cell adhesion
carbohydrate binding N-acetylgalactosamine binding oligosaccharide binding polysaccharide binding
Dictyostelium discoideum
Acetylation Cell adhesion Cytoplasm Direct protein sequencing Lectin Reference proteome
MSTQGLVQLI
MSTQGLVQLISNAQCHLRTSTNYNDVHTQFNAVLNYKNKGTNTIDGSEAWCSSIVDTNQYIVAGCEVPRTFMCVALQGRGDHDQWVTSYKIRYSLDNVTWSEYRNGAAITGVTDRNTVVNHFFDTPIRARSIAIHPLTWNNHISLRCEFYTQPVQSSVTQVGADIYTGDNCALNTGSGKREVVVPVKFQFEFATLPKVALNFDQIDCTDATNQTRIGVQPRNITTKGFDCVFYTWNANKVYSLRADYIATALE
cell adhesion cell-cell adhesion cytoskeleton organization response to cAMP response to folic acid cell surface; cytoplasm; extracellular matrix; protein complex involved in cell adhesion carbohydrate binding N-acetylgalactosamine binding oligosaccharide binding polysaccharide binding Dictyostelium discoideum Acetylati...
cell adhesion cell-cell adhesion cytoskeleton organization
cell surface; cytoplasm; extracellular matrix; protein complex involved in cell adhesion
carbohydrate binding N-acetylgalactosamine binding oligosaccharide binding polysaccharide binding
Dictyostelium discoideum
Acetylation Cell adhesion Cytoplasm Lectin Reference proteome
MSTQGLVTLL
MSTQGLVTLLGNAQCHLRTSTNYNGVHTQFNAALNYKNKGTNTIDGSEAWCSSIVDTNQYIVAGCEVPRTFMCVALQGRGDHDQWVTSYKIRYSLDNVTWSEYRNGAAITGVTDRNTVVNHFFDTPIRARSIAIHPLTWNNHISLRCEFYTQPVQSSVTQVGADIYTGDNCALNTGSGKREVVVPVKFQFEFATLPKVALNFDQIDCTDATNQTRIGVQPRNITTKGFDCVFYTWNENKVYSLRADYIATALE
cell adhesion cell-cell adhesion cytoskeleton organization cell surface; cytoplasm; extracellular matrix; protein complex involved in cell adhesion carbohydrate binding N-acetylgalactosamine binding oligosaccharide binding polysaccharide binding Dictyostelium discoideum Acetylation Cell adhesion Cytoplasm Lectin Refere...
DNA damage response maltodextrin transmembrane transport maltose transport negative regulation of maltose transport negative regulation of transmembrane transport
ATP-binding cassette (ABC) transporter complex; enzyme IIA-maltose transporter complex; maltose transport complex; membrane; plasma membrane
ABC-type maltose transporter activity
Escherichia coli
3D-structure Cell inner membrane Cell membrane Membrane Reference proteome Sugar transport Transmembrane Transmembrane helix Transport
MDVIKKKHWW
MDVIKKKHWWQSDALKWSVLGLLGLLVGYLVVLMYAQGEYLFAITTLILSSAGLYIFANRKAYAWRYVYPGMAGMGLFVLFPLVCTIAIAFTNYSSTNQLTFERAQEVLLDRSWQAGKTYNFGLYPAGDEWQLALSDGETGKNYLSDAFKFGGEQKLQLKETTAQPEGERANLRVITQNRQALSDITAILPDGNKVMMSSLRQFSGTQPLYTLDGDGTLTNNQSGVKYRPNNQIGFYQSITADGNWGDEKLSPGYTVTTGWKNFTRVFTDEGIQKPFLAIFVWTVVFSLITVFLTVAVGMVLACLVQWEALRGKAVYRVL...
DNA damage response maltodextrin transmembrane transport maltose transport negative regulation of maltose transport negative regulation of transmembrane transport ATP-binding cassette (ABC) transporter complex; enzyme IIA-maltose transporter complex; maltose transport complex; membrane; plasma membrane ABC-type maltose...
cell wall organization peptidoglycan biosynthetic process proteolysis regulation of cell shape response to antibiotic
plasma membrane
penicillin binding peptidoglycan glycosyltransferase activity serine-type D-Ala-D-Ala carboxypeptidase activity
Escherichia coli
Antibiotic resistance Carboxypeptidase Cell inner membrane Cell membrane Cell shape Cell wall biogenesis/degradation Direct protein sequencing Glycosyltransferase Hydrolase Membrane Multifunctional enzyme Peptidoglycan synthesis Protease Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix
MKFVKYFLIL
MKFVKYFLILAVCCILLGAGSIYGLYRYIEPQLPDVATLKDVRLQIPMQIYSADGELIAQYGEKRRIPVTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEVFLAIRIEQLLTKDEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLNEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQQQFDQTRTEAINANYHAPEIAFSAPYLSEMVRQEMYNRYGESAYEDGYRIYTTITRKVQQAAQQAVRNNVLDYDMRHGYRGPA...
cell wall organization peptidoglycan biosynthetic process proteolysis regulation of cell shape response to antibiotic plasma membrane penicillin binding peptidoglycan glycosyltransferase activity serine-type D-Ala-D-Ala carboxypeptidase activity Escherichia coli Antibiotic resistance Carboxypeptidase Cell inner membran...
cell wall repair peptidoglycan biosynthetic process positive regulation of bipolar cell growth proteolysis regulation of cell shape response to antibiotic
membrane; outer membrane-bounded periplasmic space; peptidoglycan-based cell wall; plasma membrane
penicillin binding peptidoglycan glycosyltransferase activity serine-type D-Ala-D-Ala carboxypeptidase activity
Escherichia coli
3D-structure Alternative initiation Antibiotic resistance Carboxypeptidase Cell inner membrane Cell membrane Cell shape Cell wall biogenesis/degradation Direct protein sequencing Glycosyltransferase Hydrolase Membrane Multifunctional enzyme Peptidoglycan synthesis Protease Reference proteome Signal-anchor Transferase T...
MAGNDREPIG
MAGNDREPIGRKGKPTRPVKQKVSRRRYEDDDDYDDYDDYEDEEPMPRKGKGKGKGRKPRGKRGWLWLLLKLAIVFAVLIAIYGVYLDQKIRSRIDGKVWQLPAAVYGRMVNLEPDMTISKNEMVKLLEATQYRQVSKMTRPGEFTVQANSIEMIRRPFDFPDSKEGQVRARLTFDGDHLATIVNMENNRQFGFFRLDPRLITMISSPNGEQRLFVPRSGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRTVQGASTLTQQLVKNLFLSSERSYWRKANEAYMALIMDARYSKDRILELYMNEVYLGQSG...
cell wall repair peptidoglycan biosynthetic process positive regulation of bipolar cell growth proteolysis regulation of cell shape response to antibiotic membrane; outer membrane-bounded periplasmic space; peptidoglycan-based cell wall; plasma membrane penicillin binding peptidoglycan glycosyltransferase activity seri...
carbohydrate transport lactose transport organic substance transport
membrane; plasma membrane
carbohydrate:proton symporter activity lactose binding lactose:proton symporter activity
Escherichia coli
3D-structure Cell inner membrane Cell membrane Formylation Membrane Reference proteome Sugar transport Symport Transmembrane Transmembrane helix Transport
MYYLKNTNFW
MYYLKNTNFWMFGLFFFFYFFIMGAYFPFFPIWLHDINHISKSDTGIIFAAISLFSLLFQPLFGLLSDKLGLRKYLLWIITGMLVMFAPFFIFIFGPLLQYNILVGSIVGGIYLGFCFNAGAPAVEAFIEKVSRRSNFEFGRARMFGCVGWALCASIVGIMFTINNQFVFWLGSGCALILAVLLFFAKTDAPSSATVANAVGANHSAFSLKLALELFRQPKLWFLSLYVIGVSCTYDVFDQQFANFFTSFFATGEQGTRVFGYVTTMGELLNASIMFFAPLIINRIGGKNALLLAGTIMSVRIIGSSFATSALEVVILKT...
carbohydrate transport lactose transport organic substance transport membrane; plasma membrane carbohydrate:proton symporter activity lactose binding lactose:proton symporter activity Escherichia coli 3D-structure Cell inner membrane Cell membrane Formylation Membrane Reference proteome Sugar transport Symport Transmem...
melibiose transport methylgalactoside transport organic substance transport
plasma membrane
melibiose:monoatomic cation symporter activity melibiose:sodium symporter activity methylgalactoside transmembrane transporter activity
Escherichia coli
Cell inner membrane Cell membrane Direct protein sequencing Membrane Reference proteome Sugar transport Symport Transmembrane Transmembrane helix Transport
MSISMTTKLS
MSISMTTKLSYGFGAFGKDFAIGIVYMYLMYYYTDVVGLSVGLVGTLFLVARIWDAINDPIMGWIVNATRSRWGKFKPWILIGTLANSVILFLLFSAHLFEGTTQIVFVCVTYILWGMTYTIMDIPFWSLVPTITLDKREREQLVPYPRFFASLAGFVTAGVTLPFVNYVGGGDRGFGFQMFTLVLIAFFIVSTIITLRNVHEVFSSDNQPSAEGSHLTLKAIVALIYKNDQLSCLLGMALAYNVASNIITGFAIYYFSYVIGDADLFPYYLSYAGAANLVTLVFFPRLVKSLSRRILWAGASILPVLSCGVLLLMALMS...
melibiose transport methylgalactoside transport organic substance transport plasma membrane melibiose:monoatomic cation symporter activity melibiose:sodium symporter activity methylgalactoside transmembrane transporter activity Escherichia coli Cell inner membrane Cell membrane Direct protein sequencing Membrane Refere...
D-ribose transmembrane transport positive chemotaxis
ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; membrane; outer membrane-bounded periplasmic space
monosaccharide binding
Escherichia coli
3D-structure Chemotaxis Direct protein sequencing Periplasm Reference proteome Signal Sugar transport Transport
MNMKKLATLV
MNMKKLATLVSAVALSATVSANAMAKDTIALVVSTLNNPFFVSLKDGAQKEADKLGYNLVVLDSQNNPAKELANVQDLTVRGTKILLINPTDSDAVGNAVKMANQANIPVITLDRQATKGEVVSHIASDNVLGGKIAGDYIAKKAGEGAKVIELQGIAGTSAARERGEGFQQAVAAHKFNVLASQPADFDRIKGLNVMQNLLTAHPDVQAVFAQNDEMALGALRALQTAGKSDVMVVGFDGTPDGEKAVNDGKLAATIAQLPDQIGAKGVETADKVLKGEKVQAKYPVDLKLVVKQ
D-ribose transmembrane transport positive chemotaxis ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; membrane; outer membrane-bounded periplasmic space monosaccharide binding Escherichia coli 3D-structure Chemotaxis Direct protein sequencing Periplasm Reference proteome Signal Suga...
cobalamin transport colicin transport intracellular iron ion homeostasis intracellular monoatomic cation homeostasis protein transport receptor-mediated bacteriophage irreversible attachment to host cell siderophore transport transmembrane transport
cell envelope; cell outer membrane; membrane; outer membrane-bounded periplasmic space; plasma membrane; plasma membrane protein complex; transmembrane transporter complex
energy transducer activity protein domain specific binding
Escherichia coli
3D-structure Bacteriocin transport Cell inner membrane Cell membrane Membrane Protein transport Reference proteome Repeat Signal-anchor Transmembrane Transmembrane helix Transport
MTLDLPRRFP
MTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESRPASPFENTAPARLTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGIVVNILFKINGTTEIQ
cobalamin transport colicin transport intracellular iron ion homeostasis intracellular monoatomic cation homeostasis protein transport receptor-mediated bacteriophage irreversible attachment to host cell siderophore transport transmembrane transport cell envelope; cell outer membrane; membrane; outer membrane-bounded p...
bile acid and bile salt transport enterobactin transport monoatomic ion transmembrane transport response to antibiotic response to organic cyclic compound response to toxic substance response to xenobiotic stimulus xenobiotic detoxification by transmembrane export across the cell outer membrane xenobiotic detoxificatio...
cell outer membrane; efflux pump complex; MacAB-TolC complex; membrane; outer membrane-bounded periplasmic space; periplasmic side of plasma membrane
bile acid transmembrane transporter activity efflux transmembrane transporter activity identical protein binding monoatomic ion channel activity porin activity
Escherichia coli
3D-structure Antibiotic resistance Cell outer membrane Direct protein sequencing Membrane Reference proteome Repeat Signal Transmembrane Transmembrane beta strand Transport
MKKLLPILIG
MKKLLPILIGLSLSGFSSLSQAENLMQVYQQARLSNPELRKSAADRDAAFEKINEARSPLLPQLGLGADYTYSNGYRDANGINSNATSASLQLTQSIFDMSKWRALTLQEKAAGIQDVTYQTDQQTLILNTATAYFNVLNAIDVLSYTQAQKEAIYRQLDQTTQRFNVGLVAITDVQNARAQYDTVLANEVTARNNLDNAVEQLRQITGNYYPELAALNVENFKTDKPQPVNALLKEAEKRNLSLLQARLSQDLAREQIRQAQDGHLPTLDLTASTGISDTSYSGSKTRGAAGTQYDDSNMGQNKVGLSFSLPIYQGGMV...
bile acid and bile salt transport enterobactin transport monoatomic ion transmembrane transport response to antibiotic response to organic cyclic compound response to toxic substance response to xenobiotic stimulus xenobiotic detoxification by transmembrane export across the cell outer membrane xenobiotic detoxificatio...
monoatomic ion transmembrane transport protein homotrimerization
cell outer membrane; membrane; monoatomic ion channel complex; pore complex
colicin transmembrane transporter activity disordered domain specific binding identical protein binding lipid binding lipopolysaccharide binding monoatomic ion channel activity porin activity
Escherichia coli
3D-structure Cell outer membrane Direct protein sequencing Ion transport Membrane Porin Reference proteome Signal Transmembrane Transmembrane beta strand Transport
MMKRNILAVI
MMKRNILAVIVPALLVAGTANAAEIYNKDGNKVDLYGKAVGLHYFSKGNGENSYGGNGDMTYARLGFKGETQINSDLTGYGQWEYNFQGNNSEGADAQTGNKTRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGRVGGVATYRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADRTNLQEAQPLGNGKKAEQWATGLKYDANNIYLAANYGETRNATPITNKFTNTSGFANKTQDVLLVAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVG...
monoatomic ion transmembrane transport protein homotrimerization cell outer membrane; membrane; monoatomic ion channel complex; pore complex colicin transmembrane transporter activity disordered domain specific binding identical protein binding lipid binding lipopolysaccharide binding monoatomic ion channel activity po...
cell motility cellular response to amino acid stimulus chemotaxis detection of chemical stimulus receptor clustering regulation of bacterial-type flagellum-dependent cell motility regulation of chemotaxis regulation of protein histidine kinase activity signal complex assembly signal transduction
methyl accepting chemotaxis protein complex; plasma membrane
identical protein binding transmembrane signaling receptor activity
Escherichia coli
3D-structure Cell inner membrane Cell membrane Chemotaxis Direct protein sequencing Membrane Methylation Reference proteome Transducer Transmembrane Transmembrane helix
MLKRIKIVTS
MLKRIKIVTSLLLVLAVFGLLQLTSGGLFFNALKNDKENFTVLQTIRQQQSTLNGSWVALLQTRNTLNRAGIRYMMDQNNIGSGSTVAELMESASISLKQAEKNWADYEALPRDPRQSTAAAAEIKRNYDIYHNALAELIQLLGAGKINEFFDQPTQGYQDGFEKQYVAYMEQNDRLHDIAVSDNNASYSQAMWILVGVMIVVLAVIFAVWFGIKASLVAPMNRLIDSIRHIAGGDLVKPIEVDGSNEMGQLAESLRHMQGELMRTVGDVRNGANAIYSGASEIATGNNDLSSRTEQQAASLEETAASMEQLTATVKQNA...
cell motility cellular response to amino acid stimulus chemotaxis detection of chemical stimulus receptor clustering regulation of bacterial-type flagellum-dependent cell motility regulation of chemotaxis regulation of protein histidine kinase activity signal complex assembly signal transduction methyl accepting chemot...
DNA damage response maltodextrin transmembrane transport monoatomic ion transport polysaccharide transport
cell outer membrane; pore complex
carbohydrate transmembrane transporter activity maltodextrin transmembrane transporter activity maltose transporting porin activity porin activity virus receptor activity
Escherichia coli
3D-structure Cell outer membrane Direct protein sequencing Disulfide bond Host cell receptor for virus entry Host-virus interaction Ion transport Membrane Porin Receptor Reference proteome Signal Sugar transport Transmembrane Transmembrane beta strand Transport
MMITLRKLPL
MMITLRKLPLAVAVAAGVMSAQAMAVDFHGYARSGIGWTGSGGEQQCFQTTGAQSKYRLGNECETYAELKLGQEVWKEGDKSFYFDTNVAYSVAQQNDWEATDPAFREANVQGKNLIEWLPGSTIWAGKRFYQRHDVHMIDFYYWDISGPGAGLENIDVGFGKLSLAATRSSEAGGSSSFASNNIYDYTNETANDVFDVRLAQMEINPGGTLELGVDYGRANLRDNYRLVDGASKDGWLFTAEHTQSVLKGFNKFVVQYATDSMTSQGKGLSQGSGVAFDNEKFAYNINNNGHMLRILDHGAISMGDNWDMMYVGMYQDI...
DNA damage response maltodextrin transmembrane transport monoatomic ion transport polysaccharide transport cell outer membrane; pore complex carbohydrate transmembrane transporter activity maltodextrin transmembrane transporter activity maltose transporting porin activity porin activity virus receptor activity Escheric...
phototransduction proton transmembrane transport
plasma membrane
monoatomic ion channel activity photoreceptor activity
Halobacterium salinarum
3D-structure Cell membrane Chromophore Direct protein sequencing Hydrogen ion transport Ion transport Membrane Photoreceptor protein Pyrrolidone carboxylic acid Receptor Reference proteome Retinal protein Sensory transduction Transmembrane Transmembrane helix Transport
MLELLPTAVE
MLELLPTAVEGVSQAQITGRPEWIWLALGTALMGLGTLYFLVKGMGVSDPDAKKFYAITTLVPAIAFTMYLSMLLGYGLTMVPFGGEQNPIYWARYADWLFTTPLLLLDLALLVDADQGTILALVGADGIMIGTGLVGALTKVYSYRFVWWAISTAAMLYILYVLFFGFTSKAESMRPEVASTFKVLRNVTVVLWSAYPVVWLIGSEGAGIVPLNIETLLFMVLDVSAKVGFGLILLRSRAIFGEAEAPEPSAGDGAAATSD
phototransduction proton transmembrane transport plasma membrane monoatomic ion channel activity photoreceptor activity Halobacterium salinarum 3D-structure Cell membrane Chromophore Direct protein sequencing Hydrogen ion transport Ion transport Membrane Photoreceptor protein Pyrrolidone carboxylic acid Receptor Refer...
mitochondrial translation mitochondrial translational elongation
mitochondrion
GTP binding GTPase activity translation elongation factor activity
Saccharomyces cerevisiae
Elongation factor GTP-binding Mitochondrion Nucleotide-binding Protein biosynthesis Reference proteome Transit peptide
MSALLPRLLT
MSALLPRLLTRTAFKASGKLLRLSSVISRTFSQTTTSYAAAFDRSKPHVNIGTIGHVDHGKTTLTAAITKTLAAKGGANFLDYAAIDKAPEERARGITISTAHVEYETAKRHYSHVDCPGHADYIKNMITGAAQMDGAIIVVAATDGQMPQTREHLLLARQVGVQHIVVFVNKVDTIDDPEMLELVEMEMRELLNEYGFDGDNAPIIMGSALCALEGRQPEIGEQAIMKLLDAVDEYIPTPERDLNKPFLMPVEDIFSISGRGTVVTGRVERGNLKKGEELEIVGHNSTPLKTTVTGIEMFRKELDSAMAGDNAGVLLRG...
mitochondrial translation mitochondrial translational elongation mitochondrion GTP binding GTPase activity translation elongation factor activity Saccharomyces cerevisiae Elongation factor GTP-binding Mitochondrion Nucleotide-binding Protein biosynthesis Reference proteome Transit peptide MSALLPRLLT MSALLPRLLTRTAFKASG...
actin filament bundle assembly cellular response to amino acid starvation negative regulation of protein kinase activity negative regulation of protein phosphorylation translation translational elongation tRNA export from nucleus
cytoplasm; cytoskeleton; cytosol; eukaryotic translation elongation factor 1 complex; fungal-type vacuole membrane; mitochondrion; ribosome
actin filament binding GDP binding GTP binding GTPase activity melatonin binding protein kinase binding ribosome binding translation elongation factor activity
Saccharomyces cerevisiae
3D-structure Actin-binding Cytoplasm Cytoskeleton Direct protein sequencing Elongation factor GTP-binding Isopeptide bond Methylation Nucleotide-binding Phosphoprotein Protein biosynthesis Reference proteome Ubl conjugation
MGKEKSHINV
MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQGVPGDNVGFNVKNVSVKEIRR...
actin filament bundle assembly cellular response to amino acid starvation negative regulation of protein kinase activity negative regulation of protein phosphorylation translation translational elongation tRNA export from nucleus cytoplasm; cytoskeleton; cytosol; eukaryotic translation elongation factor 1 complex; fung...
ribosomal large subunit biogenesis
nucleus
DNA binding metal ion binding RNA binding
Xenopus laevis
3D-structure Alternative initiation Direct protein sequencing DNA-binding Metal-binding Nucleus Phosphoprotein Reference proteome Repeat Ribosome biogenesis RNA-binding Transcription Transcription regulation Zinc Zinc-finger
MAAKVASTSS
MAAKVASTSSEEAEGSLVTEGEMGEKALPVVYKRYICSFADCGAAYNKNWKLQAHLCKHTGEKPFPCKEEGCEKGFTSLHHLTRHSLTHTGEKNFTCDSDGCDLRFTTKANMKKHFNRFHNIKICVYVCHFENCGKAFKKHNQLKVHQFSHTQQLPYECPHEGCDKRFSLPSRLKRHEKVHAGYPCKKDDSCSFVGKTWTLYLKHVAECHQDLAVCDVCNRKFRHKDYLRDHQKTHEKERTVYLCPRDGCDRSYTTAFNLRSHIQSFHEEQRPFVCEHAGCGKCFAMKKSLERHSVVHDPEKRKLKEKCPRPKRSLASRL...
ribosomal large subunit biogenesis nucleus DNA binding metal ion binding RNA binding Xenopus laevis 3D-structure Alternative initiation Direct protein sequencing DNA-binding Metal-binding Nucleus Phosphoprotein Reference proteome Repeat Ribosome biogenesis RNA-binding Transcription Transcription regulation Zinc Zinc-fi...
DNA replication DNA replication initiation DNA unwinding involved in DNA replication negative regulation of DNA-templated DNA replication initiation positive regulation of DNA-templated DNA replication initiation regulation of DNA replication regulation of DNA-templated DNA replication initiation
cytoplasmic side of plasma membrane; cytosol; DnaA-DiaA complex; DnaA-Dps complex; DnaA-HU complex; DnaA-L2 complex; DnaA-oriC complex; plasma membrane; replication inhibiting complex
ATP binding ATP hydrolysis activity DNA binding DNA replication origin binding identical protein binding sequence-specific DNA binding
Escherichia coli
3D-structure Acetylation ATP-binding Cytoplasm DNA replication DNA replication inhibitor DNA-binding Nucleotide-binding Reference proteome Repressor Transcription Transcription regulation
MSLSLWQQCL
MSLSLWQQCLARLQDELPATEFSMWIRPLQAELSDNTLALYAPNRFVLDWVRDKYLNNINGLLTSFCGADAPQLRFEVGTKPVTQTPQAAVTSNVAAPAQVAQTQPQRAAPSTRSGWDNVPAPAEPTYRSNVNVKHTFDNFVEGKSNQLARAAARQVADNPGGAYNPLFLYGGTGLGKTHLLHAVGNGIMARKPNAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEPPELETRVAILMKKADENDIRLPGE...
DNA replication DNA replication initiation DNA unwinding involved in DNA replication negative regulation of DNA-templated DNA replication initiation positive regulation of DNA-templated DNA replication initiation regulation of DNA replication regulation of DNA-templated DNA replication initiation cytoplasmic side of pl...
DNA replication proofreading DNA-templated DNA replication lagging strand elongation leading strand elongation
cytosol; DNA polymerase III complex; DNA polymerase III, core complex; replisome
3'-5' exonuclease activity DNA binding DNA-directed DNA polymerase activity exonuclease activity metal ion binding
Escherichia coli
3D-structure DNA replication DNA-directed DNA polymerase Exonuclease Hydrolase Magnesium Manganese Metal-binding Nuclease Nucleotidyltransferase Reference proteome Transferase
MSTAITRQIV
MSTAITRQIVLDTETTGMNQIGAHYEGHKIIEIGAVEVVNRRLTGNNFHVYLKPDRLVDPEAFGVHGIADEFLLDKPTFAEVADEFMDYIRGAELVIHNAAFDIGFMDYEFSLLKRDIPKTNTFCKVTDSLAVARKMFPGKRNSLDALCARYEIDNSKRTLHGALLDAQILAEVYLAMTGGQTSMAFAMEGETQQQQGEATIQRIVRQASKLRVVFATDEEIAAHEARLDLVQKKGGSCLWRA
DNA replication proofreading DNA-templated DNA replication lagging strand elongation leading strand elongation cytosol; DNA polymerase III complex; DNA polymerase III, core complex; replisome 3'-5' exonuclease activity DNA binding DNA-directed DNA polymerase activity exonuclease activity metal ion binding Escherichia c...
DNA integration viral entry into host cell viral tropism switching
host cell cytoplasm
DNA binding DNA strand exchange activity hydrolase activity ligase activity
Escherichia phage Mu
3D-structure DNA integration DNA invertase DNA recombination DNA-binding Host cytoplasm Hydrolase Late protein Ligase Reference proteome Viral receptor tropism switching Virus entry into host cell
MLIGYVRVST
MLIGYVRVSTNDQNTDLQRNALVCAGCEQIFEDKLSGTRTDRPGLKRALKRLQKGDTLVVWKLDRLGRSMKHLISLVGELRERGINFRSLTDSIDTSSPMGRFFFHVMGALAEMERELIIERTMAGLAAARNKGRIGGRPPKLTKAEWEQAGRLLAQGIPRKQVALIYDVALSTLYKKHPAKRAHIENDDRIN
DNA integration viral entry into host cell viral tropism switching host cell cytoplasm DNA binding DNA strand exchange activity hydrolase activity ligase activity Escherichia phage Mu 3D-structure DNA integration DNA invertase DNA recombination DNA-binding Host cytoplasm Hydrolase Late protein Ligase Reference proteome...
DNA duplex unwinding DNA unwinding involved in DNA replication mismatch repair mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication nucleotide-excision repair nucleotide-excision repair, DNA duplex unwinding recombinational repair replication fork processing response to radiatio...
cytosol; DNA helicase complex; single-stranded DNA-dependent ATP-dependent DNA helicase complex
3'-5' DNA helicase activity ATP binding ATP hydrolysis activity DNA binding DNA helicase activity DNA translocase activity isomerase activity protein homodimerization activity single-stranded DNA helicase activity
Escherichia coli
3D-structure ATP-binding Direct protein sequencing DNA damage DNA repair DNA replication DNA-binding Helicase Hydrolase Isomerase Nucleotide-binding Reference proteome SOS response
MDVSYLLDSL
MDVSYLLDSLNDKQREAVAAPRSNLLVLAGAGSGKTRVLVHRIAWLMSVENCSPYSIMAVTFTNKAAAEMRHRIGQLMGTSQGGMWVGTFHGLAHRLLRAHHMDANLPQDFQILDSEDQLRLLKRLIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQSYGNPVEQTWQKVYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNILVDEFQDTNNIQYAWIRLLAGDTGKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTSNILSAANALIENNNGRLGKKLWTDGADGEPISL...
DNA duplex unwinding DNA unwinding involved in DNA replication mismatch repair mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication nucleotide-excision repair nucleotide-excision repair, DNA duplex unwinding recombinational repair replication fork processing response to radiatio...
negative regulation of DNA-templated transcription regulation of DNA-templated transcription
cytosol
cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity DNA-binding transcription repressor activity identical protein binding transcription cis-regulatory region binding
Escherichia coli
3D-structure Direct protein sequencing DNA-binding Reference proteome Repressor Transcription Transcription regulation
MKPVTLYDVA
MKPVTLYDVAEYAGVSYQTVSRVVNQASHVSAKTREKVEAAMAELNYIPNRVAQQLAGKQSLLIGVATSSLALHAPSQIVAAIKSRADQLGASVVVSMVERSGVEACKAAVHNLLAQRVSGLIINYPLDDQDAIAVEAACTNVPALFLDVSDQTPINSIIFSHEDGTRLGVEHLVALGHQQIALLAGPLSSVSARLRLAGWHKYLTRNQIQPIAEREGDWSAMSGFQQTMQMLNEGIVPTAMLVANDQMALGAMRAITESGLRVGADISVVGYDDTEDSSCYIPPLTTIKQDFRLLGQTSVDRLLQLSQGQAVKGNQLLP...
negative regulation of DNA-templated transcription regulation of DNA-templated transcription cytosol cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity DNA-binding transcription repressor activity identical protein binding transcription cis-regulatory region binding Escherichi...
amino acid biosynthetic process cellular response to amino acid starvation intracellular signal transduction negative regulation of ribosomal protein gene transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II nitrogen catabolite activation of transcription from RNA polymerase II p...
nucleus; RNA polymerase II transcription regulator complex; transcription regulator complex
chromatin binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific identical protein binding mediator complex binding protein self-association RNA polymerase II cis-regulatory region s...
Saccharomyces cerevisiae
3D-structure Activator Amino-acid biosynthesis DNA-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation
MSEYQPSLFA
MSEYQPSLFALNPMGFSPLDGSKSTNENVSASTSTAKPMVGQLIFDKFIKTEEDPIIKQDTPSNLDFDFALPQTATAPDAKTVLPIPELDDAVVESFFSSSTDSTPMFEYENLEDNSKEWTSLFDNDIPVTTDDVSLADKAIESTEEVSLVPSNLEVSTTSFLPTPVLEDAKLTQTRKVKKPNSVVKKSHHVGKDDESRLDHLGVVAYNRKQRSIPLSPIVPESSDPAALKRARNTEAARRSRARKLQRMKQLEDKVEELLSKNYHLENEVARLKKLVGER
amino acid biosynthetic process cellular response to amino acid starvation intracellular signal transduction negative regulation of ribosomal protein gene transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II nitrogen catabolite activation of transcription from RNA polymerase II p...
bidirectional double-stranded viral DNA replication disruption by virus of host JAK-STAT cascade via inhibition of JAK1 activity DNA unwinding involved in DNA replication modulation by symbiont of host protein ubiquitination perturbation by virus of host G1/S transition checkpoint suppression by virus of host type I in...
host cell nucleus
ATP binding DNA replication origin binding double-stranded DNA binding helicase activity hydrolase activity identical protein binding metal ion binding single-stranded DNA binding
Simian virus 40
3D-structure Acetylation Activator Alternative initiation Alternative splicing ATP-binding Direct protein sequencing DNA replication DNA-binding Early protein G1/S host cell cycle checkpoint dysregulation by virus Glycoprotein Helicase Host nucleus Host-virus interaction Hydrolase Inhibition of host innate immune respo...
MDKVLNREES
MDKVLNREESLQLMDLLGLERSAWGNIPLMRKAYLKKCKEFHPDKGGDEEKMKKMNTLYKKMEDGVKYAHQPDFGGFWDATEIPTYGTDEWEQWWNAFNEENLFCSEEMPSSDDEATADSQHSTPPKKKRKVEDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYSVTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLMYSALTRDPFSVIEESLPGGLKEHDFNPEEAEETKQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFEMCLKCIKKEQPSHYKYHEKH...
bidirectional double-stranded viral DNA replication disruption by virus of host JAK-STAT cascade via inhibition of JAK1 activity DNA unwinding involved in DNA replication modulation by symbiont of host protein ubiquitination perturbation by virus of host G1/S transition checkpoint suppression by virus of host type I in...
disruption by virus of host JAK-STAT cascade via inhibition of JAK1 activity DNA replication perturbation by virus of host G1/S transition checkpoint suppression by virus of host type I interferon-mediated signaling pathway
host cell nucleus
ATP binding DNA replication origin binding helicase activity hydrolase activity metal ion binding
BK polyomavirus
Acetylation Activator Alternative splicing ATP-binding DNA replication DNA-binding Early protein G1/S host cell cycle checkpoint dysregulation by virus Glycoprotein Helicase Host nucleus Host-virus interaction Hydrolase Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway b...
MDKVLNREES
MDKVLNREESMELMDLLGLERAAWGNLPLMRKAYLRKCKEFHPDKGGDEDKMKRMNTLYKKMEQDVKVAHQPDFGTWSSSEVPTYGTEEWESWWSSFNEKWDEDLFCHEDMFASDEEATADSQHSTPPKKKRKVEDPKDFPSDLHQFLSQAVFSNRTLACFAVYTTKEKAQILYKKLMEKYSVTFISRHMCAGHNIIFFLTPHRHRVSAINNFCQKLCTFSFLICKGVNKEYLLYSALTRDPYHTIEESIQGGLKEHDFSPEEPEETKQVSWKLITEYAVETKCEDVFLLLGMYLEFQYNVEECKKCQKKDQPYHFKYHE...
disruption by virus of host JAK-STAT cascade via inhibition of JAK1 activity DNA replication perturbation by virus of host G1/S transition checkpoint suppression by virus of host type I interferon-mediated signaling pathway host cell nucleus ATP binding DNA replication origin binding helicase activity hydrolase activit...
protein complex oligomerization virus-mediated pore formation in host cell membrane
host cell nuclear membrane; host cell plasma membrane; host cell rough endoplasmic reticulum membrane; membrane
DNA binding monoatomic ion channel activity
JC polyomavirus
3D-structure Alternative initiation Alternative splicing Host cell membrane Host cytoplasm Host endoplasmic reticulum Host membrane Host nucleus Host-virus interaction Ion channel Ion transport Membrane Phosphoprotein Reference proteome Signal-anchor Transmembrane Transmembrane helix Transport Viral ion channel
MVLRQLSRKA
MVLRQLSRKASVKVSKTWSGTKKRAQRILIFLLEFLLDFCTGEDSVDGKKRQRHSGLTEQTYSALPEPKAT
protein complex oligomerization virus-mediated pore formation in host cell membrane host cell nuclear membrane; host cell plasma membrane; host cell rough endoplasmic reticulum membrane; membrane DNA binding monoatomic ion channel activity JC polyomavirus 3D-structure Alternative initiation Alternative splicing Host c...
caveolin-mediated endocytosis of virus by host cell viral capsid assembly virion attachment to host cell
capsomere; host cell endoplasmic reticulum; host cell nucleus; T=7 icosahedral viral capsid
identical protein binding molecular adaptor activity structural molecule activity
Simian virus 40
3D-structure Alternative initiation Alternative splicing Capsid protein Caveolin-mediated endocytosis of virus by host Direct protein sequencing Disulfide bond Host endoplasmic reticulum Host nucleus Host-virus interaction Late protein Phosphoprotein Reference proteome T=7 icosahedral capsid protein Viral attachment to...
MAPTKRKGSC
MAPTKRKGSCPGAAPKKPKEPVQVPKLVIKGGIEVLGVKTGVDSFTEVECFLNPQMGNPDEHQKGLSKSLAAEKQFTDDSPDKEQLPCYSVARIPLPNINEDLTCGNILMWEAVTVKTEVIGVTAMLNLHSGTQKTHENGAGKPIQGSNFHFFAVGGEPLELQGVLANYRTKYPAQTVTPKNATVDSQQMNTDHKAVLDKDNAYPVECWVPDPSKNENTRYFGTYTGGENVPPVLHITNTATTVLLDEQGVGPLCKADSLYVSAVDICGLFTNTSGTQQWKGLPRYFKITLRKRSVKNPYPISFLLSDLINRRTQRVDGQ...
caveolin-mediated endocytosis of virus by host cell viral capsid assembly virion attachment to host cell capsomere; host cell endoplasmic reticulum; host cell nucleus; T=7 icosahedral viral capsid identical protein binding molecular adaptor activity structural molecule activity Simian virus 40 3D-structure Alternative ...
clathrin-dependent endocytosis of virus by host cell virion attachment to host cell
host cell nucleus; T=7 icosahedral viral capsid
structural molecule activity
JC polyomavirus
3D-structure Alternative initiation Alternative splicing Capsid protein Clathrin-mediated endocytosis of virus by host Disulfide bond Host nucleus Host-virus interaction Late protein Phosphoprotein Reference proteome T=7 icosahedral capsid protein Viral attachment to host cell Viral penetration into host cytoplasm Viri...
MAPTKRKGER
MAPTKRKGERKDPVQVPKLLIRGGVEVLEVKTGVDSITEVECFLTPEMGDPDEHLRGFSKSISISDTFESDSPNRDMLPCYSVARIPLPNLNEDLTCGNILMWEAVTLKTEVIGVTSLMNVHSNGQATHDNGAGKPVQGTSFHFFSVGGEALELQGVLFNYRTKYPDGTIFPKNATVQSQVMNTEHKAYLDKNKAYPVECWVPDPTRNENTRYFGTLTGGENVPPVLHITNTATTVLLDEFGVGPLCKGDNLYLSAVDVCGMFTNRSGSQQWRGLSRYFKVQLRKRRVKNPYPISFLLTDLINRRTPRVDGQPMYGMDAQ...
clathrin-dependent endocytosis of virus by host cell virion attachment to host cell host cell nucleus; T=7 icosahedral viral capsid structural molecule activity JC polyomavirus 3D-structure Alternative initiation Alternative splicing Capsid protein Clathrin-mediated endocytosis of virus by host Disulfide bond Host nuc...
permeabilization of host organelle membrane involved in viral entry into host cell protein complex oligomerization viral entry via permeabilization of inner membrane viral penetration into host nucleus virion attachment to host cell virus-mediated pore formation in host cell membrane
host cell endoplasmic reticulum membrane; host cell nucleus; membrane; viral capsid
DNA binding monoatomic ion channel activity structural molecule activity
Simian virus 40
Alternative initiation Alternative splicing Capsid protein DNA-binding Host endoplasmic reticulum Host membrane Host nucleus Host-virus interaction Ion channel Ion transport Late protein Lipoprotein Membrane Myristate Reference proteome Transmembrane Transmembrane helix Transport Viral attachment to host cell Viral ion...
MGAALTLLGD
MGAALTLLGDLIATVSEAAAATGFSVAEIAAGEAAAAIEVQLASVATVEGLTTSEAIAAIGLIPQAYAVISGAPAAIAGFAALLQTVTGVSAVAQVGYRFFSDWDHKVSTVGLYQQPGMAVDLYRPDDYYDILFPGVQTFVHSVQYLDPRHWGPTLFNAISQAFWRVIQNDIPRLTSQELERRTQRYLRDSLARFLEETTWTVINAPVNWYNSLQDYYSTLSPIRPTMVRQVANREGLQISFGHTYDNIDEADSIQQVTERWEAQSQSPNVQSGEFIEKFEAPGGANQRTAPQWMLPLLLGLYGSVTSALKAYEDGPNKK...
permeabilization of host organelle membrane involved in viral entry into host cell protein complex oligomerization viral entry via permeabilization of inner membrane viral penetration into host nucleus virion attachment to host cell virus-mediated pore formation in host cell membrane host cell endoplasmic reticulum mem...
permeabilization of host organelle membrane involved in viral entry into host cell protein complex oligomerization viral entry via permeabilization of inner membrane viral penetration into host nucleus virion attachment to host cell virus-mediated pore formation in host cell membrane
host cell endoplasmic reticulum membrane; host cell nucleus; membrane; viral capsid
DNA binding monoatomic ion channel activity structural molecule activity
BK polyomavirus
3D-structure Alternative initiation Alternative splicing Capsid protein DNA-binding Host endoplasmic reticulum Host membrane Host nucleus Host-virus interaction Ion channel Ion transport Late protein Lipoprotein Membrane Myristate Transmembrane Transmembrane helix Transport Viral attachment to host cell Viral ion chann...
MGAALALLGD
MGAALALLGDLVASVSEAAAATGFSVAEIAAGEAAAAIEVQIASLATVEGITSTSEAIAAIGLTPQTYAVIAGAPGAIAGFAALIQTVSGISSLAQVGYRFFSDWDHKVSTVGLYQQSGMALELFNPDEYYDILFPGVNTFVNNIQYLDPRHWGPSLFATISQALWHVIRDDIPSITSQELQRRTERFFRDSLARFLEETTWTIVNAPINFYNYIQQYYSDLSPIRPSMVRQVAEREGTRVHFGHTYSIDDADSIEEVTQRMDLRNQQSVHSGEFIEKTIAPGGANQRTAPQWMLPLLLGLYGTVTPALEAYEDGPNQKK...
permeabilization of host organelle membrane involved in viral entry into host cell protein complex oligomerization viral entry via permeabilization of inner membrane viral penetration into host nucleus virion attachment to host cell virus-mediated pore formation in host cell membrane host cell endoplasmic reticulum mem...
permeabilization of host organelle membrane involved in viral entry into host cell protein complex oligomerization viral entry via permeabilization of inner membrane viral penetration into host nucleus virion attachment to host cell virus-mediated pore formation in host cell membrane
host cell endoplasmic reticulum membrane; host cell nucleus; membrane; viral capsid
DNA binding monoatomic ion channel activity structural molecule activity
JC polyomavirus
Alternative initiation Alternative splicing Capsid protein DNA-binding Host endoplasmic reticulum Host membrane Host nucleus Host-virus interaction Ion channel Ion transport Late protein Lipoprotein Membrane Myristate Reference proteome Transmembrane Transmembrane helix Transport Viral attachment to host cell Viral ion...
MGAALALLGD
MGAALALLGDLVATVSEAAAATGFSVAEIAAGEAAATIEVEIASLATVEGITSTSEAIAAIGLTPETYAVITGAPGAVAGFAALVQTVTGGSAIAQLGYRFFADWDHKVSTVGLFQQPAMALQLFNPEDYYDILFPGVNAFVNNIHYLDPRHWGPSLFSTISQAFWNLVRDDLPALTSQEIQRRTQKLFVESLARFLEETTWAIVNSPANLYNYISDYYSRLSPVRPSMVRQVAQREGTYISFGHSYTQSIDDADSIQEVTQRLDLKTPNVQSGEFIERSIAPGGANQRSAPQWMLPLLLGLYGTVTPALEAYEDGPNKK...
permeabilization of host organelle membrane involved in viral entry into host cell protein complex oligomerization viral entry via permeabilization of inner membrane viral penetration into host nucleus virion attachment to host cell virus-mediated pore formation in host cell membrane host cell endoplasmic reticulum mem...
viral entry into host cell viral penetration into host nucleus
host cell endoplasmic reticulum membrane; host cell nucleus; membrane; viral capsid
DNA binding structural molecule activity
Murine polyomavirus
Alternative initiation Alternative splicing Capsid protein DNA-binding Host endoplasmic reticulum Host membrane Host nucleus Late protein Lipoprotein Membrane Myristate Reference proteome Transmembrane Transmembrane helix Viral penetration into host nucleus Virion Virus entry into host cell
MGAALTILVD
MGAALTILVDLIEGLAEVSTLTGLSAEAILSGEALAALDGEITALTLEGVMSSETALATMGISEEVYGFVSTVPVFVSRTAGAIWLMQTVQGASTISLGIQRYLHNEEVPTVNRNMALIPWRDPALLDIYFPGVNQFAHALNVVHDWGHGLLHSVGRYVWQMVVQETQHRLEGAVRELTVRQTHTFLDGLARLLENTRWVVSNAPQSAIDAINRGASSASSGYSSLSDYYRQLGLNPPQRRALFNRIEGSMGNGGPTPAAHIQDESGEVIKFYQAQVVSHQRVTPDWMLPLILGLYGDITPTWATVIEEDGPQKKKRRL
viral entry into host cell viral penetration into host nucleus host cell endoplasmic reticulum membrane; host cell nucleus; membrane; viral capsid DNA binding structural molecule activity Murine polyomavirus Alternative initiation Alternative splicing Capsid protein DNA-binding Host endoplasmic reticulum Host membrane...
viral entry into host cell viral penetration into host nucleus
host cell endoplasmic reticulum membrane; host cell nucleus; membrane; viral capsid
DNA binding structural molecule activity
Murine polyomavirus
Alternative initiation Alternative splicing Capsid protein DNA-binding Host endoplasmic reticulum Host membrane Host nucleus Late protein Lipoprotein Membrane Myristate Reference proteome Transmembrane Transmembrane helix Viral penetration into host nucleus Virion Virus entry into host cell
MGAALTILVD
MGAALTILVDLIEGLAEVSTLTGLSAEAILSGEALAALDGEITALTLEGVMSSETALATMGISEEVYGFVSTVPVFVNRTAGAIWLMQTVQGASTISLGIQRYLHNEEVPTVNRNMALIPWRDPALLDIYFPGVNQFAHALNVVHDWGHGLLHSVGRYVWQMVVQETQHRLEGAVRELTVRQTHTFLDGLARLLENTRWVVSNAPQSAIDAINRGASSVSSGYSSLSDYYRQLGLNPPQRRALFNRIEGSMGNGGPTPAAHIQDESGEVIKFYQAPGGAHQRVTPDWMLPLILGLYGDITPTWATVIEEDGPQKKKRRL
viral entry into host cell viral penetration into host nucleus host cell endoplasmic reticulum membrane; host cell nucleus; membrane; viral capsid DNA binding structural molecule activity Murine polyomavirus Alternative initiation Alternative splicing Capsid protein DNA-binding Host endoplasmic reticulum Host membrane...
microtubule-dependent intracellular transport of viral material towards nucleus viral entry into host cell viral penetration into host nucleus
host cell endosome; host cell Golgi apparatus; host cell nucleus; viral capsid
DNA binding structural molecule activity
Human papillomavirus type 16
Capsid protein Cytoplasmic inwards viral transport Disulfide bond DNA-binding Host endosome Host Golgi apparatus Host nucleus Host-virus interaction Late protein Microtubular inwards viral transport Phosphoprotein Reference proteome Viral penetration into host nucleus Virion Virus entry into host cell
MRHKRSAKRT
MRHKRSAKRTKRASATQLYKTCKQAGTCPPDIIPKVEGKTIAEQILQYGSMGVFFGGLGIGTGSGTGGRTGYIPLGTRPPTATDTLAPVRPPLTVDPVGPSDPSIVSLVEETSFIDAGAPTSVPSIPPDVSGFSITTSTDTTPAILDINNTVTTVTTHNNPTFTDPSVLQPPTPAETGGHFTLSSSTISTHNYEEIPMDTFIVSTNPNTVTSSTPIPGSRPVARLGLYSRTTQQVKVVDPAFVTTPTKLITYDNPAYEGIDVDNTLYFSSNDNSINIAPDPDFLDIVALHRPALTSRRTGIRYSRIGNKQTLRTRSGKSI...
microtubule-dependent intracellular transport of viral material towards nucleus viral entry into host cell viral penetration into host nucleus host cell endosome; host cell Golgi apparatus; host cell nucleus; viral capsid DNA binding structural molecule activity Human papillomavirus type 16Capsid protein Cytoplasmic in...
DNA replication
host cell nucleus
ATP binding ATP hydrolysis activity DNA binding DNA helicase activity
Bovine papillomavirus type 1
3D-structure ATP-binding DNA replication DNA-binding Early protein Helicase Host nucleus Hydrolase Isopeptide bond Nucleotide-binding Phosphoprotein Ubl conjugation
MANDKGSNWD
MANDKGSNWDSGLGCSYLLTEAECESDKENEEPGAGVELSVESDRYDSQDEDFVDNASVFQGNHLEVFQALEKKAGEEQILNLKRKVLGSSQNSSGSEASETPVKRRKSGAKRRLFAENEANRVLTPLQVQGEGEGRQELNEEQAISHLHLQLVKSKNATVFKLGLFKSLFLCSFHDITRLFKNDKTTNQQWVLAVFGLAEVFFEASFELLKKQCSFLQMQKRSHEGGTCAVYLICFNTAKSRETVRNLMANTLNVREECLMLQPAKIRGLSAALFWFKSSLSPATLKHGALPEWIRAQTTLNESLQTEKFDFGTMVQWA...
DNA replication host cell nucleus ATP binding ATP hydrolysis activity DNA binding DNA helicase activity Bovine papillomavirus type 13D-structure ATP-binding DNA replication DNA-binding Early protein Helicase Host nucleus Hydrolase Isopeptide bond Nucleotide-binding Phosphoprotein Ubl conjugation MANDKGSNWD MANDKGSNWDSG...
DNA replication DNA-templated transcription regulation of DNA replication viral DNA genome replication
host cell nucleus; host cytoskeleton
DNA binding DNA-binding transcription factor activity nucleotide binding
Human papillomavirus type 16
3D-structure Activator DNA replication DNA-binding Early protein Host nucleus Isopeptide bond Phosphoprotein Reference proteome Repressor Transcription Transcription regulation Ubl conjugation
METLCQRLNV
METLCQRLNVCQDKILTHYENDSTDLRDHIDYWKHMRLECAIYYKAREMGFKHINHQVVPTLAVSKNKALQAIELQLTLETIYNSQYSNEKWTLQDVSLEVYLTAPTGCIKKHGYTVEVQFDGDICNTMHYTNWTHIYICEEASVTVVEGQVDYYGLYYVHEGIRTYFVQFKDDAEKYSKNKVWEVHAGGQVILCPTSVFSSNEVSSPEIIRQHLANHPAATHTKAVALGTEETQTTIQRPRSEPDTGNPCHTTKLLHRDSVDSAPILTAFNSSHKGRINCNSNTTPIVHLKGDANTLKCLRYRFKKHCTLYTAVSSTWH...
DNA replication DNA-templated transcription regulation of DNA replication viral DNA genome replication host cell nucleus; host cytoskeleton DNA binding DNA-binding transcription factor activity nucleotide binding Human papillomavirus type 163D-structure Activator DNA replication DNA-binding Early protein Host nucleus I...
DNA replication DNA-templated transcription regulation of DNA replication viral DNA genome replication
host cell nucleus
DNA binding DNA-binding transcription factor activity nucleotide binding
Bovine papillomavirus type 1
3D-structure Activator DNA replication DNA-binding Early protein Host nucleus Oxidation Phosphoprotein Repressor Transcription Transcription regulation
METACERLHV
METACERLHVAQETQMQLIEKSSDKLQDHILYWTAVRTENTLLYAARKKGVTVLGHCRVPHSVVCQERAKQAIEMQLSLQELSKTEFGDEPWSLLDTSWDRYMSEPKRCFKKGARVVEVEFDGNASNTNWYTVYSNLYMRTEDGWQLAKAGADGTGLYYCTMAGAGRIYYSRFGDEAARFSTTGHYSVRDQDRVYAGVSSTSSDFRDRPDGVWVASEGPEGDPAGKEAEPAQPVSSLLGSPACGPIRAGLGWVRDGPRSHPYNFPAGSGGSILRSSSTPVQGTVPVDLASRQEEEEQSPDSTEEEPVTLPRRTTNDGFHL...
DNA replication DNA-templated transcription regulation of DNA replication viral DNA genome replication host cell nucleus DNA binding DNA-binding transcription factor activity nucleotide binding Bovine papillomavirus type 13D-structure Activator DNA replication DNA-binding Early protein Host nucleus Oxidation Phosphopro...
activation of GTPase activity DNA-templated transcription modulation by symbiont of host protein ubiquitination perturbation by virus of host apoptosis positive regulation of transcription by RNA polymerase II regulation of proteolysis suppression by virus of host transcription suppression by virus of host type I inter...
host cell cytoplasm; host cell nucleus
DNA binding identical protein binding metal ion binding PDZ domain binding
Human papillomavirus type 16
3D-structure Activator DNA-binding Early protein Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host IRF3 by virus Inhibition of host RLR pathway by virus Metal-binding Modulation of host cell apoptosis by virus Oncogene Reference proteome Transcripti...
MHQKRTAMFQ
MHQKRTAMFQDPQERPRKLPQLCTELQTTIHDIILECVYCKQQLLRREVYDFAFRDLCIVYRDGNPYAVCDKCLKFYSKISEYRHYCYSLYGTTLEQQYNKPLCDLLIRCINCQKPLCPEEKQRHLDKKQRFHNIRGRWTGRCMSCCRSSRTRRETQL
activation of GTPase activity DNA-templated transcription modulation by symbiont of host protein ubiquitination perturbation by virus of host apoptosis positive regulation of transcription by RNA polymerase II regulation of proteolysis suppression by virus of host transcription suppression by virus of host type I inter...
disruption by virus of host JAK-STAT cascade via inhibition of host IRF9 activity DNA-templated transcription modulation by virus of host transcription perturbation by virus of host G1/S transition checkpoint positive regulation by symbiont of host transcription positive regulation of actin filament polymerization supp...
host cell cytoplasm; host cell nucleus
cadmium ion binding DNA binding DNA-binding transcription factor activity DNA-binding transcription factor binding protein domain specific binding zinc ion binding
Human papillomavirus type 16
3D-structure Activator DNA-binding Early protein G1/S host cell cycle checkpoint dysregulation by virus Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Metal-binding Modulation of host cell cycle by virus Onco...
MHGDTPTLHE
MHGDTPTLHEYMLDLQPETTDLYCYEQLNDSSEEEDEIDGPAGQAEPDRAHYNIVTFCCKCDSTLRLCVQSTHVDIRTLEDLLMGTLGIVCPICSQKP
disruption by virus of host JAK-STAT cascade via inhibition of host IRF9 activity DNA-templated transcription modulation by virus of host transcription perturbation by virus of host G1/S transition checkpoint positive regulation by symbiont of host transcription positive regulation of actin filament polymerization supp...
DNA replication permeabilization of host organelle membrane involved in viral entry into host cell perturbation by virus of G2/M transition of host mitotic cell cycle perturbation by virus of host G1/S transition checkpoint viral DNA genome replication viral entry via permeabilization of inner membrane
host cell nucleus
ATP binding ATP hydrolysis activity DNA binding endonuclease activity metal ion binding
Adeno-associated virus 2
3D-structure ATP-binding Covalent protein-DNA linkage DNA replication DNA-binding Endonuclease G1/S host cell cycle checkpoint dysregulation by virus Host G2/M cell cycle arrest by virus Host nucleus Host-virus interaction Hydrolase Metal-binding Modulation of host cell cycle by virus Nuclease Nucleotide-binding Refere...
MPGFYEIVIK
MPGFYEIVIKVPSDLDGHLPGISDSFVNWVAEKEWELPPDSDMDLNLIEQAPLTVAEKLQRDFLTEWRRVSKAPEALFFVQFEKGESYFHMHVLVETTGVKSMVLGRFLSQIREKLIQRIYRGIEPTLPNWFAVTKTRNGAGGGNKVVDECYIPNYLLPKTQPELQWAWTNMEQYLSACLNLTERKRLVAQHLTHVSQTQEQNKENQNPNSDAPVIRSKTSARYMELVGWLVDKGITSEKQWIQEDQASYISFNAASNSRSQIKAALDNAGKIMSLTKTAPDYLVGQQPVEDISSNRIYKILELNGYDPQYAASVFLGWA...
DNA replication permeabilization of host organelle membrane involved in viral entry into host cell perturbation by virus of G2/M transition of host mitotic cell cycle perturbation by virus of host G1/S transition checkpoint viral DNA genome replication viral entry via permeabilization of inner membrane host cell nucleu...
DNA replication modulation by virus of host transcription perturbation by virus of G2/M transition of host mitotic cell cycle perturbation by virus of host apoptosis perturbation by virus of host G1/S transition checkpoint rolling hairpin viral DNA replication
host cell nucleus
ATP binding ATP hydrolysis activity DNA binding endonuclease activity helicase activity metal ion binding
Murine minute virus ))
3D-structure ATP-binding Covalent protein-DNA linkage DNA replication DNA-binding Endonuclease G1/S host cell cycle checkpoint dysregulation by virus Helicase Host G2/M cell cycle arrest by virus Host nucleus Host-virus interaction Hydrolase Magnesium Metal-binding Modulation of host cell apoptosis by virus Modulation ...
MAGNAYSDEV
MAGNAYSDEVLGATNWLKEKSNQEVFSFVFKNENVQLNGKDIGWNSYKKELQEDELKSLQRGAETTWDQSEDMEWETTVDEMTKKQVFIFDSLVKKCLFEVLNTKNIFPGDVNWFVQHEWGKDQGWHCHVLIGGKDFSQAQGKWWRRQLNVYWSRWLVTACNVQLTPAERIKLREIAEDNEWVTLLTYKHKQTKKDYTKCVLFGNMIAYYFLTKKKISTSPPRDGGYFLSSDSGWKTNFLKEGERHLVSKLYTDDMRPETVETTVTTAQETKRGRIQTKKEVSIKTTLKELVHKRVTSPEDWMMMQPDSYIEMMAQPGGE...
DNA replication modulation by virus of host transcription perturbation by virus of G2/M transition of host mitotic cell cycle perturbation by virus of host apoptosis perturbation by virus of host G1/S transition checkpoint rolling hairpin viral DNA replication host cell nucleus ATP binding ATP hydrolysis activity DNA b...
microtubule-dependent intracellular transport of viral material towards nucleus viral entry into host cell viral penetration into host nucleus
host cell cytoplasm; T=4 icosahedral viral capsid
DNA binding RNA binding structural molecule activity
Hepatitis B virus genotype D subtype ayw
3D-structure Alternative initiation Capsid protein Cytoplasmic inwards viral transport DNA-binding Host cytoplasm Host-virus interaction Microtubular inwards viral transport Phosphoprotein Reference proteome Repeat RNA-binding T=4 icosahedral capsid protein Viral penetration into host nucleus Virion Virus entry into ho...
MDIDPYKEFG
MDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTASALYREALESPEHCSPHHTALRQAILCWGELMTLATWVGVNLEDPASRDLVVSYVNTNMGLKFRQLLWFHISCLTFGRETVIEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC
microtubule-dependent intracellular transport of viral material towards nucleus viral entry into host cell viral penetration into host nucleus host cell cytoplasm; T=4 icosahedral viral capsid DNA binding RNA binding structural molecule activity Hepatitis B virus genotype D subtype ayw 3D-structure Alternative initiat...
microtubule-dependent intracellular transport of viral material towards nucleus viral entry into host cell viral penetration into host nucleus
host cell cytoplasm; T=4 icosahedral viral capsid
DNA binding RNA binding structural molecule activity
Hepatitis B virus genotype A2 subtype adw2
Alternative initiation Capsid protein Cytoplasmic inwards viral transport DNA-binding Host cytoplasm Host-virus interaction Microtubular inwards viral transport Phosphoprotein Repeat RNA-binding T=4 icosahedral capsid protein Viral penetration into host nucleus Virion Virus entry into host cell
MDIDPYKEFG
MDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTASALYREALESPEHCSPHHTALRQAILCWGELMTLATWVGNNLEDPASRDLVVNYVNTNVGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRDRGRSPRRRTPSPRRRRSPSPRRRRSQSRESQC
microtubule-dependent intracellular transport of viral material towards nucleus viral entry into host cell viral penetration into host nucleus host cell cytoplasm; T=4 icosahedral viral capsid DNA binding RNA binding structural molecule activity Hepatitis B virus genotype A2 subtype adw2 Alternative initiation Capsid ...
microtubule-dependent intracellular transport of viral material towards nucleus viral entry into host cell viral penetration into host nucleus virus-mediated perturbation of host defense response
extracellular region; host cell cytoplasm; host cell nucleus; T=4 icosahedral viral capsid
DNA binding RNA binding structural molecule activity
Ground squirrel hepatitis virus
Alternative initiation Disulfide bond Host nucleus Host-virus interaction Reference proteome Repeat Secreted Signal Viral immunoevasion
MYLFHLCLVF
MYLFHLCLVFACVPCPTVQASKLCLGWLWDMDIDPYKEFGSSYQLLNFLPLDFFPDLNALVDTAAALYEEELTGREHCSPHHTAIRQALVCWEELTRLITWMSENTTEEVRRIIVDHVNNTWGLKVRQTLWFHLSCLTFGQHTVQEFLVSFGVWIRTPAPYRPPNAPILSTLPEHTVIRRRGGSRAARSPRRRTPSPRRRRSQSPRRRRSQSPASNC
microtubule-dependent intracellular transport of viral material towards nucleus viral entry into host cell viral penetration into host nucleus virus-mediated perturbation of host defense response extracellular region; host cell cytoplasm; host cell nucleus; T=4 icosahedral viral capsid DNA binding RNA binding structura...
suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I
endoplasmic reticulum membrane; host cell cytoplasm; host cell nucleus
molecular sequestering activity
Human herpesvirus 1
3D-structure Early protein Host cytoplasm Host nucleus Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host TAP by virus Reference proteome Viral immunoevasion
MSWALEMADT
MSWALEMADTFLDTMRVGPRTYADVRDEINKRGREDREAARTAVHDPERPLLRSPGLLPEIAPNASLGVAHRRTGGTVTDSPRNPVTR
suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I endoplasmic reticulum membrane; host cell cytoplasm; host cell nucleus molecular sequestering activity Human herpesvirus 1 3D-structure Early protein Host cytoplasm Host nucleus Host-virus interaction Inhibition of hos...
coreceptor-mediated virion attachment to host cell entry receptor-mediated virion attachment to host cell fusion of virus membrane with host plasma membrane viral entry into host cell
membrane; viral envelope; virion membrane
metal ion binding
Human herpesvirus 2
3D-structure Direct protein sequencing Disulfide bond Glycoprotein Host-virus interaction Membrane Metal-binding Signal Transmembrane Transmembrane helix Viral attachment to host cell Viral attachment to host entry receptor Viral envelope protein Virion Virus entry into host cell Zinc
MGRLTSGVGT
MGRLTSGVGTAALLVVAVGLRVVCAKYALADPSLKMADPNRFRGKNLPVLDRLTDPPGVKRVYHIQPSLEDPFQPPSIPITVYYAVLERACRSVLLHAPSEAPQIVRGASDEARKHTYNLTIAWYRMGDNCAIPITVMEYTECPYNKSLGVCPIRTQPRWSYYDSFSAVSEDNLGFLMHAPAFETAGTYLRLVKINDWTEITQFILEHRARASCKYALPLRIPPAACLTSKAYQQGVTVDSIGMLPRFIPENQRTVALYSLKIAGWHGPKPPYTSTLLPPELSDTTNATQPELVPEDPEDSALLEDPAGTVSSQIPPNWH...
coreceptor-mediated virion attachment to host cell entry receptor-mediated virion attachment to host cell fusion of virus membrane with host plasma membrane viral entry into host cell membrane; viral envelope; virion membrane metal ion binding Human herpesvirus 2 3D-structure Direct protein sequencing Disulfide bond ...
bidirectional double-stranded viral DNA replication perturbation by virus of host G1/S transition checkpoint
host cell nucleus; viral tegument
DNA binding
Epstein-Barr virus
3D-structure Activator Disulfide bond DNA-binding Early protein G1/S host cell cycle checkpoint dysregulation by virus Host nucleus Host-virus interaction Modulation of host cell cycle by virus Phosphoprotein Reference proteome Transcription Transcription regulation Virion Virion tegument
METTQTLRFK
METTQTLRFKTKALAVLSKCYDHAQTHLKGGVLQVNLLSVNYGGPRLAAVANAGTAGLISFEVSPDAVAEWQNHQSPEEAPAAVSFRNLAYGRTCVLGKELFGSAVEQASLQFYKRPQGGSRPEFVKLTMEYDDKVSKSHHTCALMPYMPPASDRLRNEQMIGQVLLMPKTASSLQKWARQQGSGGVKVTLNPDLYVTTYTSGEACLTLDYKPLSVGPYEAFTGPVAKAQDVGAVEAHVVCSVAADSLAAALSLCRIPAVSVPILRFYRSGIIAVVAGLLTSAGDLPLDLSVILFNHASEEAAASTASEPEDKSPRVQPL...
bidirectional double-stranded viral DNA replication perturbation by virus of host G1/S transition checkpoint host cell nucleus; viral tegument DNA binding Epstein-Barr virus 3D-structure Activator Disulfide bond DNA-binding Early protein G1/S host cell cycle checkpoint dysregulation by virus Host nucleus Host-virus i...
perturbation by virus of host G0/G1 transition checkpoint perturbation by virus of host G1/S transition checkpoint positive regulation of DNA-templated transcription regulation of DNA-templated transcription release from viral latency suppression by virus of host viral-induced cytoplasmic pattern recognition receptor s...
chromatin; host cell nucleus
DNA binding DNA-binding transcription factor activity protein dimerization activity sequence-specific DNA binding
Epstein-Barr virus
3D-structure DNA-binding Early protein G0/G1 host cell cycle checkpoint dysregulation by virus G1/S host cell cycle checkpoint dysregulation by virus Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host IRF7 by virus Inhibition of host RLR pathway by virus Modulation...
MMDPNSTSED
MMDPNSTSEDVKFTPDPYQVPFVQAFDQATRVYQDLGGPSQAPLPCVLWPVLPEPLPQGQLTAYHVSTAPTGSWFSAPQPAPENAYQAYAAPQLFPVSDITQNQQTNQAGGEAPQPGDNSTVQTAAAVVFACPGANQGQQLADIGVPQPAPVAAPARRTRKPQQPESLEECDSELEIKRYKNRVASRKCRAKFKQLLQHYREVAAAKSSENDRLRLLLKQMCPSLDVDSIIPRTPDVLHEDLLNF
perturbation by virus of host G0/G1 transition checkpoint perturbation by virus of host G1/S transition checkpoint positive regulation of DNA-templated transcription regulation of DNA-templated transcription release from viral latency suppression by virus of host viral-induced cytoplasmic pattern recognition receptor s...
negative regulation of NLRP3 inflammasome complex assembly suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host PKR signaling suppression by virus of host type I interferon-mediated signaling pathway
host cell mitochondrial outer membrane; host cell plasma membrane; mitochondrial outer membrane
protein serine/threonine kinase inhibitor activity protein-macromolecule adaptor activity
Epstein-Barr virus
3D-structure Disulfide bond Early protein Host cell membrane Host membrane Host mitochondrion Host mitochondrion outer membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Inhibiti...
MLSTMAPGST
MLSTMAPGSTVGTLVANMTSVNATEDACTKSYSAFLSGMTSLLLVLLILLTLAGILFIIFVRKLVHRMDVWLIALLIELLLWVLGKMIQEFSSTGLCLLTQNMMFLGLMCSVWTHLGMALEKTLALFSRTPKRTSHRNVCLYLMGVFCLVLLLIIILLITMGPDANLNRGPNMCREGPTKGMHTAVQGLKAGCYLLAAVLIVLLTVIIIWKLLRTKFGRKPRLICNVTFTGLICAFSWFMLSLPLLFLGEAGSLGFDCTESLVARYYPGPAACLALLLIILYAWSFSHFMDSLKNQVTVTARYFRRVPSQST
negative regulation of NLRP3 inflammasome complex assembly suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host PKR signaling suppression by virus of host type I interferon-mediated signaling pathway host cell mitochondrial outer membrane; host...
positive regulation of DNA-templated transcription regulation of DNA replication suppression by virus of host antigen processing and presentation suppression by virus of host NF-kappaB cascade symbiont-mediated disruption of host cell PML body viral latency
host cell PML body
DNA binding DNA-binding transcription factor activity endonuclease activity enzyme-substrate adaptor activity
Epstein-Barr virus
3D-structure Activator Covalent protein-DNA linkage DNA-binding Endonuclease Host nucleus Host-virus interaction Hydrolase Inhibition of host adaptive immune response by virus Inhibition of host NF-kappa-B by virus Inhibition of host proteasome antigen processing by virus Nuclease Phosphoprotein Reference proteome Tran...
MSDEGPGTGP
MSDEGPGTGPGNGLGEKGDTSGPEGSGGSGPQRRGGDNHGRGRGRGRGRGGGRPGAPGGSGSGPRHRDGVRRPQKRPSCIGCKGTHGGTGAGAGAGGAGAGGAGAGGGAGAGGGAGGAGGAGGAGAGGGAGAGGGAGGAGGAGAGGGAGAGGGAGGAGAGGGAGGAGGAGAGGGAGAGGGAGGAGAGGGAGGAGGAGAGGGAGAGGAGGAGGAGAGGAGAGGGAGGAGGAGAGGAGAGGAGAGGAGAGGAGGAGAGGAGGAGAGGAGGAGAGGGAGGAGAGGGAGGAGAGGAGGAGAGGAGGAGAGGAGGAGAGGGAGAG...
positive regulation of DNA-templated transcription regulation of DNA replication suppression by virus of host antigen processing and presentation suppression by virus of host NF-kappaB cascade symbiont-mediated disruption of host cell PML body viral latency host cell PML body DNA binding DNA-binding transcription facto...
proteolysis viral release from host cell
host cell cytoplasm; host cell nucleus
identical protein binding serine-type endopeptidase activity
Epstein-Barr virus
3D-structure Alternative promoter usage Host cytoplasm Host nucleus Hydrolase Phosphoprotein Protease Reference proteome Serine protease Viral capsid assembly Viral release from host cell
MVQAPSVYVC
MVQAPSVYVCGFVERPDAPPKDACLHLDPLTVKSQLPLKKPLPLTVEHLPDAPVGSVFGLYQSRAGLFSAASITSGDFLSLLDSIYHDCDIAQSQRLPLPREPKVEALHAWLPSLSLASLHPDIPQTTADGGKLSFFDHVSICALGRRRGTTAVYGTDLAWVLKHFSDLEPSIAAQIENDANAAKRESGCPEDHPLPLTKLIAKAIDAGFLRNRVETLRQDRGVANIPAESYLKASDAPDLQKPDKALQSPPPASTDPATMLSGNAGEGATACGGSAAAGQDLISVPRNTFMTLLQTNLDNKPPRQTPLPYAAPLPPFSH...
proteolysis viral release from host cell host cell cytoplasm; host cell nucleus identical protein binding serine-type endopeptidase activity Epstein-Barr virus 3D-structure Alternative promoter usage Host cytoplasm Host nucleus Hydrolase Phosphoprotein Protease Reference proteome Serine protease Viral capsid assembly...
perturbation by virus of host apoptosis
host cell cytoplasm; host cell nucleus
SUMO ligase activity
Human adenovirus C serotype 5
Alternative splicing Early protein Host cytoplasm Host nucleus Host-virus interaction Modulation of host cell apoptosis by virus
MERRNPSERG
MERRNPSERGVPAGFSGHASVESGCETQESPATVVFRPPGDNTDGGAAAAAGGSQAAAAGAEPMEPESRPGPSGMNVVQVAELYPELRRILTITEDGQGLKGVKRERGACEATEEARNLAFSLMTRHRPECITFQQIKDNCANELDLLAQKYSIEQLTTYWLQPGDDFEEAIRVYAKVALRPDCKYKISKLVNIRNCCYISGNGAEVEIDTEDRVAFRCSMINMWPGVLGMDGVVIMNVRFTGPNFSGTVFLANTNLILHGVSFYGFNNTCVEAWTDVRVRGCAFYCCWKGVVCRPKSRASIKKCLFERCTLGILSEGNS...
perturbation by virus of host apoptosis host cell cytoplasm; host cell nucleus SUMO ligase activity Human adenovirus C serotype 5 Alternative splicing Early protein Host cytoplasm Host nucleus Host-virus interaction Modulation of host cell apoptosis by virus MERRNPSERG MERRNPSERGVPAGFSGHASVESGCETQESPATVVFRPPGDNTDGGAAA...
proteolysis
host cell nucleus; virion component
cysteine-type endopeptidase activity cysteine-type peptidase activity DNA binding
Human adenovirus C serotype 2
3D-structure Autocatalytic cleavage Disulfide bond DNA-binding Host nucleus Hydrolase Late protein Protease Reference proteome Thiol protease Virion
MGSSEQELKA
MGSSEQELKAIVKDLGCGPYFLGTYDKRFPGFVSPHKLACAIVNTAGRETGGVHWMAFAWNPRSKTCYLFEPFGFSDQRLKQVYQFEYESLLRRSAIASSPDRCITLEKSTQSVQGPNSAACGLFCCMFLHAFANWPQTPMDHNPTMNLITGVPNSMLNSPQVQPTLRRNQEQLYSFLERHSPYFRSHSAQIRSATSFCHLKNM
proteolysis host cell nucleus; virion component cysteine-type endopeptidase activity cysteine-type peptidase activity DNA binding Human adenovirus C serotype 2 3D-structure Autocatalytic cleavage Disulfide bond DNA-binding Host nucleus Hydrolase Late protein Protease Reference proteome Thiol protease Virion MGSSEQELKA...
disruption by virus of host JAK-STAT cascade via inhibition of STAT1 activity DNA-templated viral transcription modulation by symbiont of host protein ubiquitination perturbation by virus of host G1/S transition checkpoint regulation of DNA-templated transcription suppression by virus of host gene expression suppressio...
host cell nucleus
metal ion binding
Human adenovirus C serotype 2
Activator Alternative splicing Early protein Eukaryotic host gene expression shutoff by virus Eukaryotic host transcription shutoff by virus G1/S host cell cycle checkpoint dysregulation by virus Host gene expression shutoff by virus Host nucleus Host-virus interaction Inhibition of eukaryotic host transcription initia...
MRHIICHGGV
MRHIICHGGVITEEMAASLLDQLIEEVLADNLPPPSHFEPPTLHELYDLDVTAPEDPNEEAVSQIFPDSVMLAVQEGIDLLTFPPAPGSPEPPHLSRQPEQPEQRALGPVSMPNLVPEVIDLTCHEAGFPPSDDEDEEGEEFVLDYVEHPGHGCRSCHYHRRNTGDPDIMCSLCYMRTCGMFVYSPVSEPEPEPEPEPEPARPTRRPKLVPAILRRPTSPVSRECNSSTDSCDSGPSNTPPEIHPVVPLCPIKPVAVRVGGRRQAVECIEDLLNESGQPLDLSCKRPRP
disruption by virus of host JAK-STAT cascade via inhibition of STAT1 activity DNA-templated viral transcription modulation by symbiont of host protein ubiquitination perturbation by virus of host G1/S transition checkpoint regulation of DNA-templated transcription suppression by virus of host gene expression suppressio...
disruption by virus of host JAK-STAT cascade via inhibition of STAT1 activity modulation by symbiont of host protein ubiquitination perturbation by virus of host G1/S transition checkpoint positive regulation of cell population proliferation positive regulation of protein sumoylation regulation by virus of viral protei...
host cell nucleus
DNA-binding transcription factor binding metal ion binding molecular adaptor activity molecular sequestering activity
Human adenovirus C serotype 5
3D-structure Activator Alternative splicing Early protein Eukaryotic host gene expression shutoff by virus Eukaryotic host transcription shutoff by virus G1/S host cell cycle checkpoint dysregulation by virus Host gene expression shutoff by virus Host nucleus Host-virus interaction Inhibition of eukaryotic host transcr...
MRHIICHGGV
MRHIICHGGVITEEMAASLLDQLIEEVLADNLPPPSHFEPPTLHELYDLDVTAPEDPNEEAVSQIFPDSVMLAVQEGIDLLTFPPAPGSPEPPHLSRQPEQPEQRALGPVSMPNLVPEVIDLTCHEAGFPPSDDEDEEGEEFVLDYVEHPGHGCRSCHYHRRNTGDPDIMCSLCYMRTCGMFVYSPVSEPEPEPEPEPEPARPTRRPKMAPAILRRPTSPVSRECNSSTDSCDSGPSNTPPEIHPVVPLCPIKPVAVRVGGRRQAVECIEDLLNEPGQPLDLSCKRPRP
disruption by virus of host JAK-STAT cascade via inhibition of STAT1 activity modulation by symbiont of host protein ubiquitination perturbation by virus of host G1/S transition checkpoint positive regulation of cell population proliferation positive regulation of protein sumoylation regulation by virus of viral protei...
disruption by virus of host JAK-STAT cascade via inhibition of STAT1 activity modulation by symbiont of host protein ubiquitination perturbation by virus of host G1/S transition checkpoint regulation of DNA-templated transcription suppression by virus of host NF-kappaB cascade suppression by virus of host type I interf...
host cell nucleus
metal ion binding molecular sequestering activity
Human adenovirus A serotype 12
Activator Alternative splicing Early protein G1/S host cell cycle checkpoint dysregulation by virus Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Inhibition of host NF-kappa-B by virus Inhibition of host STAT1 by virus Met...
MRTEMTPLVL
MRTEMTPLVLSYQEADDILEHLVDNFFNEVPSDDDLYVPSLYELYDLDVESAGEDNNEQAVNEFFPESLILAASEGLFLPEPPVLSPVCEPIGGECMPQLHPEDMDLLCYEMGFPCSDSEDEQDENGMAHVSASAAAAAADREREEFQLDHPELPGHNCKSCEHHRNSTGNTDLMCSLCYLRAYNMFIYSPVSDNEPEPNSTLDGDERPSPPKLGSAVPEGVIKPVPQRVTGRRRCAVESILDLIQEEEREQTVPVDLSVKRPRCN
disruption by virus of host JAK-STAT cascade via inhibition of STAT1 activity modulation by symbiont of host protein ubiquitination perturbation by virus of host G1/S transition checkpoint regulation of DNA-templated transcription suppression by virus of host NF-kappaB cascade suppression by virus of host type I interf...
DNA replication DNA unwinding involved in DNA replication DNA-templated transcription positive regulation of DNA replication viral DNA strand displacement replication
nuclear viral factory; viral capsid
DNA binding single-stranded DNA binding zinc ion binding
Human adenovirus C serotype 2
DNA replication DNA-binding Early protein Host nucleus Host-virus interaction Metal-binding Phosphoprotein Reference proteome Viral DNA replication Zinc
MASREEEQRE
MASREEEQRETTPERGRGAARRPPTMEDVSSPSPSPPPPRAPPKKRLRRRLESEDEEDSSQDALVPRTPSPRPSTSTADLAIASKKKKKRPSPKPERPPSPEVIVDSEEEREDVALQMVGFSNPPVLIKHGKGGKRTVRRLNEDDPVARGMRTQEEKEESSEAESESTVINPLSLPIVSAWEKGMEAARALMDKYHVDNDLKANFKLLPDQVEALAAVCKTWLNEEHRGLQLTFTSNKTFVTMMGRFLQAYLQSFAEVTYKHHEPTGCALWLHRCAEIEGELKCLHGSIMINKEHVIEMDVTSENGQRALKEQSSKAKIV...
DNA replication DNA unwinding involved in DNA replication DNA-templated transcription positive regulation of DNA replication viral DNA strand displacement replication nuclear viral factory; viral capsid DNA binding single-stranded DNA binding zinc ion binding Human adenovirus C serotype 2 DNA replication DNA-binding E...
DNA duplex unwinding DNA unwinding involved in DNA replication DNA-templated transcription positive regulation of DNA replication viral DNA genome replication viral DNA strand displacement replication
host cell nucleus; viral capsid
DNA binding identical protein binding single-stranded DNA binding zinc ion binding
Human adenovirus C serotype 5
3D-structure DNA replication DNA-binding Early protein Host nucleus Host-virus interaction Metal-binding Phosphoprotein Viral DNA replication Zinc
MASREEEQRE
MASREEEQRETTPERGRGAARRPPTMEDVSSPSPSPPPPRAPPKKRMRRRIESEDEEDSSQDALVPRTPSPRPSTSAADLAIAPKKKKKRPSPKPERPPSPEVIVDSEEEREDVALQMVGFSNPPVLIKHGKGGKRTVRRLNEDDPVARGMRTQEEEEEPSEAESEITVMNPLSVPIVSAWEKGMEAARALMDKYHVDNDLKANFKLLPDQVEALAAVCKTWLNEEHRGLQLTFTSKKTFVTMMGRFLQAYLQSFAEVTYKHHEPTGCALWLHRCAEIEGELKCLHGSIMINKEHVIEMDVTSENGQRALKEQSSKAKIV...
DNA duplex unwinding DNA unwinding involved in DNA replication DNA-templated transcription positive regulation of DNA replication viral DNA genome replication viral DNA strand displacement replication host cell nucleus; viral capsid DNA binding identical protein binding single-stranded DNA binding zinc ion binding Huma...
DNA replication viral DNA strand displacement replication
host cell nuclear matrix; host cell nucleus
double-stranded DNA binding single-stranded DNA binding
Human adenovirus C serotype 2
Covalent protein-DNA linkage Direct protein sequencing DNA replication DNA-binding Host nucleus Phosphoprotein Reference proteome Viral DNA replication
MALSVNDCAR
MALSVNDCARLTGQSVPTMEHFLPLRNIWNRVRDFPRASTTAAGITWMSRYIYGYHRLMLEDLAPGAPATLRWPLYRQPPPHFLVGYQYLVRTCNDYVFDSRAYSRLRYTELSQPGHQTVNWSVMANCTYTINTGAYHRFVDMDDFQSTLTQVQQAILAERVVADLALLQPMRGFGVTRMGGRGRHLRPNSAAAVAIDARDAGQEEGEEEVPVERLMQDYYKDLRRCQNEAWGMADRLRIQQAGPKDMVLLSTIRRLKTAYFNYIISSTSARNNPDRHPLPPATVLSLPCDCDWLDAFLERFSDPVDADSLRSLGGGVPT...
DNA replication viral DNA strand displacement replication host cell nuclear matrix; host cell nucleus double-stranded DNA binding single-stranded DNA binding Human adenovirus C serotype 2 Covalent protein-DNA linkage Direct protein sequencing DNA replication DNA-binding Host nucleus Phosphoprotein Reference proteome V...
DNA-templated transcription nuclear capsid assembly regulation of DNA-templated transcription viral DNA genome packaging viral DNA genome packaging via site-specific sequence recognition viral release from host cell viral transcription
host cell nucleolus; host cell nucleoplasm; virion component
ATP binding DNA binding
Human adenovirus C serotype 2
Activator ATP-binding DNA-binding Host nucleus Nucleotide-binding Phosphoprotein Reference proteome Transcription Transcription regulation Viral genome packaging Viral release from host cell Virion
METRGRRPAA
METRGRRPAALQHQQDQPQAHPGQRAARSAPLHRDPDYADEDPAPVERHDPGPSGRAPTTAVQRKPPQPAKRGDMLDRDAVEHVTELWDRLELLGQTLKSMPTADGLKPLKNFASLQELLSLGGERLLAHLVRENMQVRDMLNEVAPLLRDDGSCSSLNYQLQPVIGVIYGPTGCGKSQLLRNLLSSQLISPTPETVFFIAPQVDMIPPSELKAWEMQICEGNYAPGPDGTIIPQSGTLRPRFVKMAYDDLILEHNYDVSDPRNIFAQAAARGPIAIIMDECMENLGGHKGVSKFFHAFPSKLHDKFPKCTGYTVLVVLH...
DNA-templated transcription nuclear capsid assembly regulation of DNA-templated transcription viral DNA genome packaging viral DNA genome packaging via site-specific sequence recognition viral release from host cell viral transcription host cell nucleolus; host cell nucleoplasm; virion component ATP binding DNA binding...
DNA-templated transcription viral RNA genome replication
host cell cytoplasmic vesicle membrane; membrane
hydrolase activity metal ion binding nucleotide binding poly(A) RNA polymerase activity RNA binding RNA-dependent RNA polymerase activity
Middelburg virus
Host cytoplasmic vesicle Host membrane Hydrolase Membrane Metal-binding Nucleotide-binding Nucleotidyltransferase RNA-binding RNA-directed RNA polymerase Transferase Ubl conjugation Viral RNA replication Zinc
DADLAAVYRA
DADLAAVYRAVASLADETVRTMAIPLLSTGTFAGGKDRVLQSLNHLFTALDTTDVDVTIYCRDKSWEKKIQEAIDMRTATELLDDDTTVMKELTRVHPDSCLVGRSGFSTVDGRLHSYLEGTRFHQTAVDVAERPTLWPRREEANEQITHYVLGESMEAIRTKCPVDDTDSSAPPCTVPCLCRYAMTPERVHRLRAAQVKQFTVCSSFPLPKYKIPGVQRVACSAVMLFNHDVPALVSPRKYREPSISSESSSSGLSVFDLDIGSDSEYEPMEPVQPEPLIDLAVVEETAPVRLERVAPVAAPRRARATPFTLEQRVVAP...
DNA-templated transcription viral RNA genome replication host cell cytoplasmic vesicle membrane; membrane hydrolase activity metal ion binding nucleotide binding poly(A) RNA polymerase activity RNA binding RNA-dependent RNA polymerase activity Middelburg virusHost cytoplasmic vesicle Host membrane Hydrolase Membrane Me...
proteolysis viral procapsid maturation
host cell nucleolus; host cell nucleoplasm; host cell plasma membrane; membrane; viral capsid
aspartic-type endopeptidase activity nucleic acid binding structural constituent of virion zinc ion binding
Rous sarcoma virus subgroup C
3D-structure Aspartyl protease Capsid protein Direct protein sequencing Host cell membrane Host membrane Host nucleus Hydrolase Membrane Metal-binding Protease Repeat Ribosomal frameshifting Viral capsid assembly Viral capsid maturation Viral matrix protein Viral release from host cell Virion Zinc Zinc-finger
MEAVIKVISS
MEAVIKVISSACKTYCGKTSPSKKEIGAMLSLLQKEGLLMSPSDLYSPGSWDPITAALSQRAMILGKSGELKTWGLVLGALKAAREEQVTSEQAKFWLGLGGGRVSPPGPECIEKPATERRIDKGEEVGETTVQRDAKMAPEETATPKTVGTSCYHCGTAIGCNCATASAPPPPYVGSGLYPSLAGVGEQQGQGGDTPPGAEQSRAEPGHAGQAPGPALTDWARVREELASTGPPVVAMPVVIKTEGPAWTPLEPKLITRLADTVRTKGLRSPITMAEVEALMSSPLLPHDVTNLMRVILGPAPYALWMDAWGVQLQTVI...
proteolysis viral procapsid maturation host cell nucleolus; host cell nucleoplasm; host cell plasma membrane; membrane; viral capsid aspartic-type endopeptidase activity nucleic acid binding structural constituent of virion zinc ion binding Rous sarcoma virus subgroup C 3D-structure Aspartyl protease Capsid protein Di...
viral budding via host ESCRT complex
host cell late endosome membrane; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid
RNA binding structural constituent of virion zinc ion binding
Woolly monkey sarcoma virus
Capsid protein Coiled coil Host cell membrane Host cytoplasm Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Phosphoprotein RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral matrix protein Viral nucleoprotein Viral release from host cell Virion Zi...
MGQNNSTPLS
MGQNNSTPLSLTLDHWKDVRTRAHNLSVKIRKGKWQTFCSSEWPTFGVGWPPEGTFNLSVIFAVKRIVFQETGGHPDQVPYIVVWQDLAQSPPPWVPPSAKIAVVSSPENTRGPSAGRPSAPPRPPIYPATDDLLLLSEPPPYPAALPPPLAPPAVGPAPGQAPDSSDPEGPAAGTRSRRARSPADDSGPDSTVILPLRAIGPPAEPNGLVPLQYWPFSSADLYNWKSNHPSFSENPAGLTGLLESLMFSHQPTWDDCQQLLQILFTTEERERILLEARKNVLGDNGAPTQLENLINEAFPLNRPQWDYNTAAGRERLLV...
viral budding via host ESCRT complex host cell late endosome membrane; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid RNA binding structural constituent of virion zinc ion binding Woolly monkey sarcoma virus Capsid protein Coiled coil Host cell membrane Host cytoplasm Host endosome H...
viral budding via host ESCRT complex
host cell late endosome membrane; host cell plasma membrane; host cell uropod; host multivesicular body; membrane; viral nucleocapsid
RNA binding structural constituent of virion zinc ion binding
Moloney murine leukemia virus
3D-structure Alternative initiation Capsid protein Coiled coil Direct protein sequencing Host cell membrane Host cytoplasm Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Phosphoprotein Reference proteome RNA-binding Ubl conjugation Viral budding Viral budding via the hos...
MGQTVTTPLS
MGQTVTTPLSLTLGHWKDVERIAHNQSVDVKKRRWVTFCSAEWPTFNVGWPRDGTFNRDLITQVKIKVFSPGPHGHPDQVPYIVTWEALAFDPPPWVKPFVHPKPPPPLPPSAPSLPLEPPRSTPPRSSLYPALTPSLGAKPKPQVLSDSGGPLIDLLTEDPPPYRDPRPPPSDRDGNGGEATPAGEAPDPSPMASRLRGRREPPVADSTTSQAFPLRAGGNGQLQYWPFSSSDLYNWKNNNPSFSEDPGKLTALIESVLITHQPTWDDCQQLLGTLLTGEEKQRVLLEARKAVRGDDGRPTQLPNEVDAAFPLERPDWD...
viral budding via host ESCRT complex host cell late endosome membrane; host cell plasma membrane; host cell uropod; host multivesicular body; membrane; viral nucleocapsid RNA binding structural constituent of virion zinc ion binding Moloney murine leukemia virus 3D-structure Alternative initiation Capsid protein Coile...
viral budding via host ESCRT complex
host cell plasma membrane; membrane; viral nucleocapsid
nucleic acid binding structural constituent of virion zinc ion binding
Moloney murine sarcoma virus
Capsid protein Direct protein sequencing Host cell membrane Host membrane Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Viral budding Viral budding via the host ESCRT complexes Viral matrix protein Viral nucleoprotein Viral release from host cell Virion Zinc Zinc-finger
MGQTVTTPLS
MGQTVTTPLSLTLDHWKDVERLAHNQSVDVKKRRWVTFCSAEWPTFNVGWPRDGTFNRDLITQVKIKVFSPGPHGHPDQVPYIVTWEALAFDPPPWVKPFVHPKPPPPLLPSAPSLPLEPPLSTPPQSSLYPALTPSLGAKPKPQVLSDSGGPLIDLLTEDPPPYRDPRPPPSDRDGDSGEATPAGEAPDPSPMASRLRGRREPPVADSTTSQAFPLRTGGNGQLQYWPFSSSDLYNWKNNNPSFSEDPGKLTALIESVLITHQPTWDDCQQLLGTLLTGEEKQRVLLEARKAVRGDDGRPTQLPNEVDAAFPLERPDWE...
viral budding via host ESCRT complex host cell plasma membrane; membrane; viral nucleocapsid nucleic acid binding structural constituent of virion zinc ion binding Moloney murine sarcoma virus Capsid protein Direct protein sequencing Host cell membrane Host membrane Host-virus interaction Lipoprotein Membrane Metal-bin...
viral budding via host ESCRT complex
host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid
RNA binding structural constituent of virion zinc ion binding
AKV murine leukemia virus murine leukemia virus)
3D-structure Alternative initiation Capsid protein Coiled coil Host cell membrane Host cytoplasm Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Phosphoprotein RNA-binding Ubl conjugation Viral budding Viral budding via the host ESCRT complexes Viral matrix protein Viral ...
MGQTVTTPLS
MGQTVTTPLSLTLEHWEDVQRIASNQSVDVKKRRWVTFCSAEWPTFGVGWPQDGTFNLDIILQVKSKVFSPGPHGHPDQVPYIVTWEAIAYEPPPWVKPFVSPKLSPSPTAPILPSGPSTQPPPRSALYPALTPSIKPRPSKPQVLSDNGGPLIDLLSEDPPPYGGQGLSSSDGDGDREEATSTSEIPAPSPIVSRLRGKRDPPAADSTTSRAFPLRLGGNGQLQYWPFSSSDLYNWKNNNPSFSEDPGKLTALIESVLTTHQPTWDDCQQLLGTLLTGEEKQRVLLEARKAVRGNDGRPTQLPNEVDAAFPLERPDWDY...
viral budding via host ESCRT complex host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid RNA binding structural constituent of virion zinc ion binding AKV murine leukemia virus murine leukemia virus)3D-structure Alternative initiation Capsid protein Coiled coil Host cell membrane Host cyt...
viral budding via host ESCRT complex
host cell late endosome membrane; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid
RNA binding structural constituent of virion zinc ion binding
Baboon endogenous virus
Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Phosphoprotein RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral matrix protein Viral nucleoprotein Viral release from host cell Virion Zinc Zinc-fing...
MGQTLTTPLS
MGQTLTTPLSLTLTHFSDVRARAHNLSVGVRKGRWQTFCSSEWPTLHVGWPRDGTFDLSVILQVKTKVMDPGPHGHPDQVAYIITWEDLVRNPPPWVKPFLHTPSTSKSTLLALEVPKNRTLDPPKPVLPDESQQDLLFQDPLPHPPHNPLLEPPPYNSPSPPVLSPVSPTTPSAPTPSSLVSSSTPPSSPAPPELTPRTPPQTPRLRLRRAEGQDGPSTWQSSLFPLRTVNRTIQYWPFSASDLYNWKTHNPSFSQDPQALTSLIESILLTHQPTWDDCQQLLQVLLTTEERQRVLLEARKNVPGPGGLPTQLPNEIDE...
viral budding via host ESCRT complex host cell late endosome membrane; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid RNA binding structural constituent of virion zinc ion binding Baboon endogenous virus Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host...
viral process
viral nucleocapsid
nucleic acid binding structural molecule activity zinc ion binding
Human T-cell leukemia virus 1
3D-structure Capsid protein Direct protein sequencing Disulfide bond Host-virus interaction Lipoprotein Metal-binding Myristate Phosphoprotein Repeat Ribosomal frameshifting Ubl conjugation Viral nucleoprotein Virion Zinc Zinc-finger
MGQIFSRSAS
MGQIFSRSASPIPRPPRGLAAHHWLNFLQAAYRLEPGPSSYDFHQLKKFLKIALETPARICPINYSLLASLLPKGYPGRVNEILHILIQTQAQIPSRPAPPPPSSPTHDPPDSDPQIPPPYVEPTAPQVLPVMHPHGAPPNHRPWQMKDLQAIKQEVSQAAPGSPQFMQTIRLAVQQFDPTAKDLQDLLQYLCSSLVASLHHQQLDSLISEAETRGITGYNPLAGPLRVQANNPQQQGLRREYQQLWLAAFAALPGSAKDPSWASILQGLEEPYHAFVERLNIALDNGLPEGTPKDPILRSLAYSNANKECQKLLQARGH...
viral process viral nucleocapsid nucleic acid binding structural molecule activity zinc ion binding Human T-cell leukemia virus 1 3D-structure Capsid protein Direct protein sequencing Disulfide bond Host-virus interaction Lipoprotein Metal-binding Myristate Phosphoprotein Repeat Ribosomal frameshifting Ubl conjugation...
viral process
viral nucleocapsid
nucleic acid binding structural molecule activity zinc ion binding
Human T-cell leukemia virus 2
3D-structure Capsid protein Host-virus interaction Lipoprotein Metal-binding Myristate Reference proteome Repeat Ribosomal frameshifting Ubl conjugation Viral nucleoprotein Virion Zinc Zinc-finger
MGQIHGLSPT
MGQIHGLSPTPIPKAPRGLSTHHWLNFLQAAYRLQPRPSDFDFQQLRRFLKLALKTPIWLNPIDYSLLASLIPKGYPGRVVEIINILVKNQVSPSAPAAPVPTPICPTTTPPPPPPPSPEAHVPPPYVEPTTTQCFPILHPPGAPSAHRPWQMKDLQAIKQEVSSSALGSPQFMQTLRLAVQQFDPTAKDLQDLLQYLCSSLVVSLHHQQLNTLITEAETRGMTGYNPMAGPLRMQANNPAQQGLRREYQNLWLAAFSTLPGNTRDPSWAAILQGLEEPYCAFVERLNVALDNGLPEGTPKEPILRSLAYSNANKECQKI...
viral process viral nucleocapsid nucleic acid binding structural molecule activity zinc ion binding Human T-cell leukemia virus 2 3D-structure Capsid protein Host-virus interaction Lipoprotein Metal-binding Myristate Reference proteome Repeat Ribosomal frameshifting Ubl conjugation Viral nucleoprotein Virion Zinc Zinc-...
viral budding via host ESCRT complex
host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane
identical protein binding RNA binding structural molecule activity zinc ion binding
Human immunodeficiency virus type 1 group M subtype B
3D-structure AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Methylation Myristate Phosphoprotein Reference proteome Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexe...
MGARASVLSG
MGARASVLSGGELDRWEKIRLRPGGKKKYKLKHIVWASRELERFAVNPGLLETSEGCRQILGQLQPSLQTGSEELRSLYNTVATLYCVHQRIEIKDTKEALDKIEEEQNKSKKKAQQAAADTGHSSQVSQNYPIVQNIQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRVHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTNNPPIPVGEIYKRWIILGLNKIVRMYSPTSILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNWMTET...
viral budding via host ESCRT complex host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane identical protein binding RNA binding structural molecule activity zinc ion binding Human immunodeficiency virus type 1 group M subtype B 3D-structure AIDS Capsid p...
viral budding via host ESCRT complex
host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane
RNA binding structural molecule activity zinc ion binding
Human immunodeficiency virus type 1 group M subtype B
AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Methylation Myristate Phosphoprotein Reference proteome Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucle...
MGARASVLSG
MGARASVLSGGELDRWEKIRLRPGGKKKYKLKHIVWASRELERFAVNPGLLETSEGCRQILGQLQPSLQTGSEELRSLYNTVATLYCVHQRIEIKDTKEALDKIEEEQNKSKKKAQQAAADTGHSSQVSQNYPIVQNIQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRVHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTNNPPIPVGEIYKRWIILGLNKIVRMYSPTSILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNWMTET...
viral budding via host ESCRT complex host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane RNA binding structural molecule activity zinc ion binding Human immunodeficiency virus type 1 group M subtype B AIDS Capsid protein Host cell membrane Host cytoplas...
viral budding via host ESCRT complex
host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane
RNA binding structural molecule activity zinc ion binding
Human immunodeficiency virus type 1 group M subtype B
3D-structure AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Methylation Myristate Phosphoprotein Reference proteome Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexe...
MGARASVLSG
MGARASVLSGGELDKWEKIRLRPGGKKKYKLKHIVWASRELERFAVNPGLLETSEGCRQILGQLQPSLQTGSEELRSLYNTVATLYCVHQRIDVKDTKEALEKIEEEQNKSKKKAQQAAAAAGTGNSSQVSQNYPIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRVHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTNNPPIPVGEIYKRWIILGLNKIVRMYSPTSILDIRQGPKEPFRDYVDRFYKTLRAEQASQDVKNWMT...
viral budding via host ESCRT complex host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane RNA binding structural molecule activity zinc ion binding Human immunodeficiency virus type 1 group M subtype B 3D-structure AIDS Capsid protein Host cell membrane ...
proteolysis suppression by virus of host gene expression
viral nucleocapsid
aspartic-type endopeptidase activity nucleic acid binding structural molecule activity zinc ion binding
Human T-cell leukemia virus 2
3D-structure Aspartyl protease Capsid protein Eukaryotic host gene expression shutoff by virus Eukaryotic host translation shutoff by virus Host gene expression shutoff by virus Host-virus interaction Hydrolase Lipoprotein Metal-binding Myristate Protease Reference proteome Repeat Ribosomal frameshifting Viral nucleopr...
MGQIHGLSPT
MGQIHGLSPTPIPKAPRGLSTHHWLNFLQAAYRLQPRPSDFDFQQLRRFLKLALKTPIWLNPIDYSLLASLIPKGYPGRVVEIINILVKNQVSPSAPAAPVPTPICPTTTPPPPPPPSPEAHVPPPYVEPTTTQCFPILHPPGAPSAHRPWQMKDLQAIKQEVSSSALGSPQFMQTLRLAVQQFDPTAKDLQDLLQYLCSSLVVSLHHQQLNTLITEAETRGMTGYNPMAGPLRMQANNPAQQGLRREYQNLWLAAFSTLPGNTRDPSWAAILQGLEEPYCAFVERLNVALDNGLPEGTPKEPILRSLAYSNANKECQKI...
proteolysis suppression by virus of host gene expression viral nucleocapsid aspartic-type endopeptidase activity nucleic acid binding structural molecule activity zinc ion binding Human T-cell leukemia virus 2 3D-structure Aspartyl protease Capsid protein Eukaryotic host gene expression shutoff by virus Eukaryotic host...
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral p...
host cell endosome membrane; host cell perinuclear region of cytoplasm; host cell periphery; host cell plasma membrane; membrane; viral envelope; virion membrane
CD4 receptor binding protein-containing complex binding structural molecule activity
Human immunodeficiency virus type 1 group M subtype B
3D-structure AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Direct protein sequencing Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane...
MRVKEKYQHL
MRVKEKYQHLWRWGWRWGTMLLGMLMICSATEKLWVTVYYGVPVWKEATTTLFCASDAKAYDTEVHNVWATHACVPTDPNPQEVVLVNVTENFNMWKNDMVEQMHEDIISLWDQSLKPCVKLTPLCVSLKCTDLKNDTNTNSSSGRMIMEKGEIKNCSFNISTSIRGKVQKEYAFFYKLDIIPIDNDTTSYTLTSCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNNKTFNGTGPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEVVIRSANFTDNAKTIIVQLNQSVEINCTRPNNNTRKSIRIQRGPGRAFVTI...
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral p...
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral p...
host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane
structural molecule activity
Human immunodeficiency virus type 1 group M subtype B
3D-structure AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Li...
MRVKEKYQHL
MRVKEKYQHLWRWGWKWGTMLLGILMICSATEKLWVTVYYGVPVWKEATTTLFCASDAKAYDTEVHNVWATHACVPTDPNPQEVVLVNVTENFNMWKNDMVEQMHEDIISLWDQSLKPCVKLTPLCVSLKCTDLGNATNTNSSNTNSSSGEMMMEKGEIKNCSFNISTSIRGKVQKEYAFFYKLDIIPIDNDTTSYTLTSCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNNKTFNGTGPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEVVIRSANFTDNAKTIIVQLNQSVEINCTRPNNNTRKSIRIQRGPGR...
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral p...
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral p...
host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane
structural molecule activity
Human immunodeficiency virus type 1 group M subtype B
3D-structure AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Li...
MKVKGTRRNY
MKVKGTRRNYQHLWRWGTLLLGMLMICSATEKLWVTVYYGVPVWKEATTTLFCASDARAYDTEVHNVWATHACVPTDPNPQEVVLGNVTENFNMWKNNMVEQMQEDIISLWDQSLKPCVKLTPLCVTLNCTDLGKATNTNSSNWKEEIKGEIKNCSFNITTSIRDKIQKENALFRNLDVVPIDNASTTTNYTNYRLIHCNRSVITQACPKVSFEPIPIHYCTPAGFAILKCNNKTFNGKGPCTNVSTVQCTHGIRPIVSTQLLLNGSLAEEEVVIRSDNFTNNAKTIIVQLNESVAINCTRPNNNTRKSIYIGPGRAFHT...
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral p...
fusion of virus membrane with host plasma membrane viral entry into host cell virion attachment to host cell
host cell plasma membrane; membrane; viral envelope; virion membrane
identical protein binding metal ion binding
Moloney murine leukemia virus
3D-structure Cleavage on pair of basic residues Coiled coil Direct protein sequencing Disulfide bond Fusion of virus membrane with host cell membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host membrane Host-virus interaction Lipoprotein Membrane Metal-binding Palmitate Reference pr...
MARSTLSKPL
MARSTLSKPLKNKVNPRGPLIPLILLMLRGVSTASPGSSPHQVYNITWEVTNGDRETVWATSGNHPLWTWWPDLTPDLCMLAHHGPSYWGLEYQSPFSSPPGPPCCSGGSSPGCSRDCEEPLTSLTPRCNTAWNRLKLDQTTHKSNEGFYVCPGPHRPRESKSCGGPDSFYCAYWGCETTGRAYWKPSSSWDFITVNNNLTSDQAVQVCKDNKWCNPLVIRFTDAGRRVTSWTTGHYWGLRLYVSGQDPGLTFGIRLRYQNLGPRVPIGPNPVLADQQPLSKPKPVKSPSVTKPPSGTPLSPTQLPPAGTENRLLNLVDG...
fusion of virus membrane with host plasma membrane viral entry into host cell virion attachment to host cell host cell plasma membrane; membrane; viral envelope; virion membrane identical protein binding metal ion binding Moloney murine leukemia virus 3D-structure Cleavage on pair of basic residues Coiled coil Direct ...
fusion of virus membrane with host plasma membrane viral entry into host cell virion attachment to host cell
host cell plasma membrane; membrane; viral envelope; virion membrane
metal ion binding
AKV murine leukemia virus murine leukemia virus)
Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host cell membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host membrane Host-virus interaction Lipoprotein Membrane Metal-binding Palmitate Signal Transmembrane Transmembrane helix Viral atta...
MESTTLSKPF
MESTTLSKPFKNQVNPWGPLIVLLILGGVNPVTLGNSPHQVFNLTWEVTNGDRETVWAITGNHPLWTWWPDLTPDLCMLALHGPSYWGLEYRAPFSPPPGPPCCSGSSDSTPGCSRDCEEPLTSYTPRCNTAWNRLKLSKVTHAHNGGFYVCPGPHRPRWARSCGGPESFYCASWGCETTGRASWKPSSSWDYITVSNNLTSDQATPVCKGNEWCNSLTIRFTSFGKQATSWVTGHWWGLRLYVSGHDPGLIFGIRLKITDSGPRVPIGPNPVLSDRRPPSRPRPTRSPPPSNSTPTETPLTLPEPPPAGVENRLLNLVK...
fusion of virus membrane with host plasma membrane viral entry into host cell virion attachment to host cell host cell plasma membrane; membrane; viral envelope; virion membrane metal ion binding AKV murine leukemia virus murine leukemia virus)Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of vir...
fusion of virus membrane with host plasma membrane suppression by virus of host antigen processing and presentation viral entry into host cell virion attachment to host cell
host cell plasma membrane; membrane; viral envelope; virion membrane
metal ion binding
Friend murine leukemia virus
3D-structure Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host cell membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host proteasome ...
MACSTLPKSP
MACSTLPKSPKDKIDPRDLLIPLILFLSLKGARSAAPGSSPHQVYNITWEVTNGDRETVWAISGNHPLWTWWPVLTPDLCMLALSGPPHWGLEYQAPYSSPPGPPCCSGSSGSSAGCSRDCDEPLTSLTPRCNTAWNRLKLDQVTHKSSEGFYVCPGSHRPREAKSCGGPDSFYCASWGCETTGRVYWKPSSSWDYITVDNNLTTSQAVQVCKDNKWCNPLAIQFTNAGKQVTSWTTGHYWGLRLYVSGRDPGLTFGIRLRYQNLGPRVPIGPNPVLADQLSLPRPNPLPKPAKSPPASNSTPTLISPSPTPTQPPPAGT...
fusion of virus membrane with host plasma membrane suppression by virus of host antigen processing and presentation viral entry into host cell virion attachment to host cell host cell plasma membrane; membrane; viral envelope; virion membrane metal ion binding Friend murine leukemia virus 3D-structure Cleavage on pair...
negative regulation of CD4 production perturbation by virus of host immune response regulation of calcium-mediated signaling suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC cla...
extracellular region; host cell Golgi membrane; host cell plasma membrane; membrane; virion component
ATPase binding CD4 receptor binding GTP binding MHC class I protein binding protein kinase binding SH3 domain binding signaling receptor binding thioesterase binding
Human immunodeficiency virus type 1 group M subtype B
3D-structure AIDS Apoptosis Early protein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host autophagy by virus Inhibition of host MHC class I molecule presentation by virus Inhibition of host MHC class II molecule present...
MGGKWSKSSV
MGGKWSKSSVIGWPAVRERMRRAEPAADGVGAASRDLEKHGAITSSNTAANNAACAWLEAQEEEKVGFPVTPQVPLRPMTYKAAVDLSHFLKEKGGLEGLIHSQRRQDILDLWIYHTQGYFPDWQNYTPGPGIRYPLTFGWCYKLVPVEPDKVEEANKGENTSLLHPVSLHGMDDPEREVLEWRFDSRLAFHHVARELHPEYFKNC
negative regulation of CD4 production perturbation by virus of host immune response regulation of calcium-mediated signaling suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC cla...
negative regulation of CD4 production perturbation by virus of host immune response regulation of calcium-mediated signaling regulation of T cell activation suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentatio...
extracellular region; host cell Golgi membrane; host cell plasma membrane; membrane; virion component
ATPase binding calmodulin binding CD4 receptor binding GTP binding MHC class I protein binding peptidase activator activity protein kinase binding SH3 domain binding signaling receptor binding thioesterase binding
Human immunodeficiency virus type 1 group M subtype B
3D-structure AIDS Apoptosis Direct protein sequencing Early protein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host autophagy by virus Inhibition of host MHC class I molecule presentation by virus Inhibition of host MHC...
MGGKWSKSSV
MGGKWSKSSVVGWPTVRERMRRAEPAADGVGAASRDLEKHGAITSSNTAATNAACAWLEAQEEEEVGFPVTPQVPLRPMTYKAAVDLSHFLKEKGGLEGLIHSQRRQDILDLWIYHTQGYFPDWQNYTPGPGVRYPLTFGWCYKLVPVEPDKVEEANKGENTSLLHPVSLHGMDDPEREVLEWRFDSRLAFHHVARELHPEYFKNC
negative regulation of CD4 production perturbation by virus of host immune response regulation of calcium-mediated signaling regulation of T cell activation suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentatio...
activation of transmembrane receptor protein tyrosine kinase activity endocytosis involved in viral entry into host cell suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I...
extracellular region; host cell Golgi membrane; host cell plasma membrane; membrane; virion component
GTP binding SH3 domain binding
Human immunodeficiency virus type 1 group M subtype B
3D-structure AIDS Apoptosis Early protein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host autophagy by virus Inhibition of host MHC class I molecule presentation by virus Inhibition of host MHC class II molecule present...
MGGKWSKRSM
MGGKWSKRSMGGWSAIRERMRRAEPRAEPAADGVGAVSRDLEKHGAITSSNTAATNADCAWLEAQEEEEVGFPVRPQVPLRPMTYKAALDISHFLKEKGGLEGLIWSQRRQEILDLWIYHTQGYFPDWQNYTPGPGIRYPLTFGWCFKLVPVEPEKVEEANEGENNSLLHPMSLHGMEDAEKEVLVWRFDSKLAFHHMARELHPEYYKDC
activation of transmembrane receptor protein tyrosine kinase activity endocytosis involved in viral entry into host cell suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I...
induction by virus of host NF-kappaB cascade perturbation by virus of host G0/G1 transition checkpoint perturbation by virus of host G1/S transition checkpoint peturbation by virus of host exit from mitosis positive regulation of DNA-templated transcription
host cell cytoplasm; host cell nucleus
DNA binding metal ion binding SH3 domain binding
Human T-cell leukemia virus 1
3D-structure Activation of host NF-kappa-B by virus Activator DNA-binding G0/G1 host cell cycle checkpoint dysregulation by virus G1/S host cell cycle checkpoint dysregulation by virus Host cytoplasm Host nucleus Host-virus interaction Inhibition of host mitotic exit by virus Metal-binding Modulation of host cell cycle...
MAHFPGFGQS
MAHFPGFGQSLLFGYPVYVFGDCVQGDWCPISGGLCSARLHRHALLATCPEHQITWDPIDGRVIGSALQFLIPRLPSFPTQRTSKTLKVLTPPITHTTPNIPPSFLQAMRKYSPFRNGYMEPTLGQHLPTLSFPDPGLRPQNLYTLWGGSVVCMYLYQLSPPITWPLLPHVIFCHPGQLGAFLTNVPYKRIEELLYKISLTTGALIILPEDCLPTTLFQPARAPVTLTAWQNGLLPFHSTLTTPGLIWTFTDGTPMISGPCPKDGQPSLVLQSSSFIFHKFQTKAYHPSFLLSHGLIQYSSFHSLHLLFEEYTNIPISLL...
induction by virus of host NF-kappaB cascade perturbation by virus of host G0/G1 transition checkpoint perturbation by virus of host G1/S transition checkpoint peturbation by virus of host exit from mitosis positive regulation of DNA-templated transcription host cell cytoplasm; host cell nucleus DNA binding metal ion b...
perturbation by virus of host G0/G1 transition checkpoint positive regulation of DNA-templated transcription
host cell cytoplasm; host cell nucleus
2 iron, 2 sulfur cluster binding DNA binding metal ion binding SH3 domain binding
Human T-cell leukemia virus 2
Activator DNA-binding G0/G1 host cell cycle checkpoint dysregulation by virus Host cytoplasm Host nucleus Host-virus interaction Metal-binding Modulation of host cell cycle by virus Oncogene Phosphoprotein Reference proteome SH3-binding Transcription Transcription regulation Zinc Zinc-finger
MAHFPGFGQS
MAHFPGFGQSLLYGYPVYVFGDCVQADWCPVSGGLCSTRLHRHALLATCPEHQLTWDPIDGRVVSSPLQYLIPRLPSFPTQRTSRTLKVLTPPTTPVSPKVPPAFFQSMRKHTPYRNGCLEPTLGDQLPSLAFPEPGLRPQNIYTTWGKTVVCLYLYQLSPPMTWPLIPHVIFCHPRQLGAFLTKVPLKRLEELLYKMFLHTGTVIVLPEDDLPTTMFQPVRAPCIQTAWCTGLLPYHSILTTPGLIWTFNDGSPMISGPYPKAGQPSLVVQSSLLIFEKFETKAFHPSYLLSHQLIQYSSFHNLHLLFDEYTNIPVSIL...
perturbation by virus of host G0/G1 transition checkpoint positive regulation of DNA-templated transcription host cell cytoplasm; host cell nucleus 2 iron, 2 sulfur cluster binding DNA binding metal ion binding SH3 domain binding Human T-cell leukemia virus 2 Activator DNA-binding G0/G1 host cell cycle checkpoint dysre...