Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
|---|---|---|---|---|---|---|---|
suppression by virus of host NF-kappaB cascade suppression by virus of host PKR signaling suppression by virus of host type I interferon-mediated signaling pathway suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity suppression by v... | helical viral capsid; host cell cytoplasm; ribonucleoprotein complex; viral nucleocapsid | protein serine/threonine kinase inhibitor activity RNA binding | Human respiratory syncytial virus A | 3D-structure Capsid protein Helical capsid protein Host cytoplasm Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Inhibition of host MAVS by virus Inhibition of host MDA5 by virus Inhibition of host NF-kappa-B by virus Inhibition of host... | MALSKVKLND | MALSKVKLNDTLNKDQLLSSSKYTIQRSTGDSIDTPNYDVQKHINKLCGMLLITEDANHKFTGLIGMLYAMSRLGREDTIKILRDAGYHVKANGVDVTTHRQDINGKEMKFEVLTLASLTTEIQINIEIESRKSYKKMLKEMGEVAPEYRHDSPDCGMIILCIAALVITKLAAGDRSGLTAVIRRANNVLKNEMKRYKGLLPKDIANSFYEVFEKHPHFIDVFVHFGIAQSSTRGGSRVEGIFAGLFMNAYGAGQVMLRWGVLAKSVKNIMLGHASVQAEMEQVVEVYEYAQKLGGEAGFYHILNNPKASLLSLTQFPHF... | suppression by virus of host NF-kappaB cascade suppression by virus of host PKR signaling suppression by virus of host type I interferon-mediated signaling pathway suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity suppression by v... |
entry receptor-mediated virion attachment to host cell fusion of virus membrane with host plasma membrane positive regulation of syncytium formation by virus viral entry into host cell | host cell Golgi membrane; host cell plasma membrane; membrane; viral envelope; virion membrane | identical protein binding | Human respiratory syncytial virus A | 3D-structure Cleavage on pair of basic residues Coiled coil Direct protein sequencing Disulfide bond Fusion of virus membrane with host cell membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Lipoprotein Membrane Palmitate Signa... | MELLILKANA | MELLILKANAITTILTAVTFCFASGQNITEEFYQSTCSAVSKGYLSALRTGWYTSVITIELSNIKENKCNGTDAKVKLIKQELDKYKNAVTELQLLMQSTPPTNNRARRELPRFMNYTLNNAKKTNVTLSKKRKRRFLGFLLGVGSAIASGVAVSKVLHLEGEVNKIKSALLSTNKAVVSLSNGVSVLTSKVLDLKNYIDKQLLPIVNKQSCSISNIETVIEFQQKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMSNNVQIVRQQSYSIMSIIKEEVLAYVVQLPLYGVIDTPCWKLHTSP... | entry receptor-mediated virion attachment to host cell fusion of virus membrane with host plasma membrane positive regulation of syncytium formation by virus viral entry into host cell host cell Golgi membrane; host cell plasma membrane; membrane; viral envelope; virion membrane identical protein binding Human respirat... |
suppression by virus of host NF-kappaB cascade viral life cycle | host cell cytoplasm; virion component | RNA-dependent RNA polymerase activity | Human respiratory syncytial virus A | 3D-structure Host cytoplasm Host-virus interaction Inhibition of host NF-kappa-B by virus Phosphoprotein Viral RNA replication Virion | MEKFAPEFHG | MEKFAPEFHGEDANNRATKFLESIKGKFTSPKDPKKKDSIISVNSIDIEVTKESPITSNSTIINPTNETDDTAGNKPNYQRKPLVSFKEDPTPSDNPFSKLYKETIETFDNNEEESSYSYEEINDQTNDNITARLDRIDEKLSEILGMLHTLVVASAGPTSARDGIRDAMIGLREEMIEKIRTEALMTNDRLEAMARLRNEESEKMAKDTSDEVSLNPTSEKLNNLLEGNDSDNDLSLEDF | suppression by virus of host NF-kappaB cascade viral life cycle host cell cytoplasm; virion component RNA-dependent RNA polymerase activity Human respiratory syncytial virus A 3D-structure Host cytoplasm Host-virus interaction Inhibition of host NF-kappa-B by virus Phosphoprotein Viral RNA replication Virion MEKFAPEFHG... |
7-methylguanosine mRNA capping cap snatching DNA-templated transcription negative stranded viral RNA replication suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibiti... | host cell mitochondrion; host cell nucleus; virion component | RNA binding RNA-dependent RNA polymerase activity | Influenza A virus ) | Alternative splicing Cap snatching Eukaryotic host gene expression shutoff by virus Eukaryotic host transcription shutoff by virus Host gene expression shutoff by virus Host mitochondrion Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host MAVS by virus Inhibition o... | MERIKELRNL | MERIKELRNLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPALRMKWMMAMKYPITADKRITEMIPERNEQGQTLWSKMNDAGSDRVMVSPLAVTWWNRNGPVTSTVHYPKIYKTYFEKVERLKHGTFGPVHFRNQVKIRRRVDINPGHADLSAKEAQDVIMEVVFPNEVGARILTSESQLTTTKEKKEELQGCKISPLMVAYMLERELVRKTRFLPVAGGTSSVYIEVLHLTQGTCWEQMYTPGGEARNDDVDQSLIIAARNIVRRATVSADPLASLLEMCHSTQIGGIRMVNILRQNPTEEQAVDICKAAMGLRIS... | 7-methylguanosine mRNA capping cap snatching DNA-templated transcription negative stranded viral RNA replication suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibiti... |
7-methylguanosine mRNA capping cap snatching DNA-templated transcription suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity viral RNA genome rep... | extracellular region; host cell mitochondrion; host cell nucleus; virion component | RNA binding RNA-dependent RNA polymerase activity | Influenza A virus | 3D-structure Alternative splicing Cap snatching Eukaryotic host gene expression shutoff by virus Eukaryotic host transcription shutoff by virus Host gene expression shutoff by virus Host mitochondrion Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host MAVS by virus... | MERIKELRNL | MERIKELRNLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPALRMKWMMAMKYPITADKRITEMIPERNEQGQTLWSKMNDAGSDRVMVSPLAVTWWNRNGPITNTVHYPKIYKTYFERVERLKHGTFGPVHFRNQVKIRRRVDINPGHADLSAKEAQDVIMEVVFPNEVGARILTSESQLTITKEKKEELQDCKISPLMVAYMLERELVRKTRFLPVAGGTSSVYIEVLHLTQGTCWEQMYTPGGEVRNDDVDQSLIIAARNIVRRAAVSADPLASLLEMCHSTQIGGIRMVDILRQNPTEEQAVDICKAAMGLRIS... | 7-methylguanosine mRNA capping cap snatching DNA-templated transcription suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity viral RNA genome rep... |
DNA-templated transcription negative stranded viral RNA replication suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity viral transcription | host cell cytoplasm; host cell nucleus | nucleotide binding RNA binding RNA-dependent RNA polymerase activity | Influenza A virus ) | Eukaryotic host gene expression shutoff by virus Eukaryotic host transcription shutoff by virus Host cytoplasm Host gene expression shutoff by virus Host nucleus Host-virus interaction Inhibition of host RNA polymerase II by virus Nucleotide-binding Nucleotidyltransferase Phosphoprotein Reference proteome RNA-directed ... | MDVNPTLLFL | MDVNPTLLFLKVPAQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYSERGRWTTNTETGAPQLNPIDGPLPEDNEPSGYAQTDCVLEAMAFLEESHPGIFETSCLETMEVVQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVFRSNGLTANESGRLIDFLKDVMESMNKEEMEITTHFQRKRRVRDNMTKKMVTQRTIGKRKQRLNKRSYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVETLARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTEISFTITGDNTKWNENQNPRMFLA... | DNA-templated transcription negative stranded viral RNA replication suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity viral transcription host cell cytoplasm; host cell nucleus nucleotide binding RNA binding RNA-dependent RNA polymerase activity Influenza A virus )Eukaryotic ... |
DNA-templated transcription suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity viral RNA genome replication viral transcription | extracellular region; host cell cytoplasm; host cell nucleus | nucleotide binding RNA binding RNA-dependent RNA polymerase activity | Influenza A virus | 3D-structure Eukaryotic host gene expression shutoff by virus Eukaryotic host transcription shutoff by virus Host cytoplasm Host gene expression shutoff by virus Host nucleus Host-virus interaction Inhibition of host RNA polymerase II by virus Nucleotide-binding Nucleotidyltransferase Phosphoprotein Reference proteome ... | MDVNPTLLFL | MDVNPTLLFLKVPAQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYSEKGRWTTNTETGAPQLNPIDGPLPEDNEPSGYAQTDCVLEAMAFLEESHPGIFENSCIETMEVVQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVFRSNGLTANESGRLIDFLKDVMESMKKEEMGITTHFQRKRRVRDNMTKKMITQRTIGKKKQRLNKRSYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVETLARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTELSFTITGDNTKWNENQNPRMFLA... | DNA-templated transcription suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity viral RNA genome replication viral transcription extracellular region; host cell cytoplasm; host cell nucleus nucleotide binding RNA binding RNA-dependent RNA polymerase activity Influenza A virus 3D... |
cap snatching DNA-templated transcription suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity viral RNA genome replication | extracellular region; host cell cytoplasm; host cell nucleus | endonuclease activity metal ion binding RNA binding | Influenza A virus | 3D-structure Cap snatching Endonuclease Eukaryotic host gene expression shutoff by virus Eukaryotic host transcription shutoff by virus Host cytoplasm Host gene expression shutoff by virus Host nucleus Host-virus interaction Hydrolase Inhibition of host RNA polymerase II by virus Manganese Metal-binding Nuclease Phosph... | MEDFVRQCFN | MEDFVRQCFNPMIVELAEKTMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIIVELGDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEETIEERFEITGTMRKLADQSLPPNFSSLENFRAYVDGFEPNGYIEGKLSQMSKEVNARIEPFLKTTPRPLRLPNGPPCSQRSKFLLMDALKLSIEDPSHEGEGIPLYDAIKCMRTFFGWKEP... | cap snatching DNA-templated transcription suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity viral RNA genome replication extracellular region; host cell cytoplasm; host cell nucleus endonuclease activity metal ion binding RNA binding Influenza A virus 3D-structure Cap snatchin... |
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane viral budding from plasma membrane virion attachment to host cell | host cell plasma membrane; membrane; viral envelope; virion membrane | host cell surface receptor binding identical protein binding | Influenza A virus | 3D-structure Clathrin- and caveolin-independent endocytosis of virus by host Clathrin-mediated endocytosis of virus by host Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Hemagglutinin Host cell membrane Host membrane Host-virus interaction ... | MKTIIALSYI | MKTIIALSYIFCLVFAQDLPGNDNNSTATLCLGHHAVPNGTLVKTITNDQIEVTNATELVQSSSTGKICNNPHRILDGINCTLIDALLGDPHCDGFQNEKWDLFVERSKAFSNCYPYDVPDYASLRSLVASSGTLEFINEGFNWTGVTQNGGSSACKRGPDSGFFSRLNWLYKSGSTYPVQNVTMPNNDNSDKLYIWGVHHPSTDKEQTNLYVQASGKVTVSTKRSQQTIIPNVGSRPWVRGLSSRISIYWTIVKPGDILVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIGTCSSECITPNGSIPNDKPFQNVNKITYG... | clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane viral budding from plasma membrane virion attachment to host cell host cell plasma membrane; membrane; viral envelope; virion membrane host cell surface receptor b... |
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane viral budding from plasma membrane virion attachment to host cell | host cell plasma membrane; membrane; viral envelope; virion membrane | host cell surface receptor binding | Influenza A virus ) ) | 3D-structure Clathrin- and caveolin-independent endocytosis of virus by host Clathrin-mediated endocytosis of virus by host Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Hemagglutinin Host cell membrane Host membrane Host-virus interaction ... | MKTIIALSYI | MKTIIALSYIFCLALGQDLPGNDNNTATLCLGHHAVPNGTLVKTITDDQIEVTNATELVQSSSTGKICNNPHRILDGIDCTLIDALLGDPHCDVFQNETWDLFVERSKAFSNCYPYDVPDYASLRSLVASSGTLEFITEGFTWTGVTQNGGSNACKRGPDSGFFSRLNWLTKSGSTYPVLNVTMPNNDNFDKLYIWGVHHPSTNQEQTSLYVQASGRVTVSTRRSQQTIIPNIGSRPWVRGQSSRISIYWTIVKPGDVLVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIDTCISECITPNGSIPNDKPFQNVNKITYGA... | clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane viral budding from plasma membrane virion attachment to host cell host cell plasma membrane; membrane; viral envelope; virion membrane host cell surface receptor b... |
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane viral budding from plasma membrane virion attachment to host cell | host cell plasma membrane; membrane; viral envelope; virion membrane | host cell surface receptor binding | Influenza A virus | 3D-structure Clathrin- and caveolin-independent endocytosis of virus by host Clathrin-mediated endocytosis of virus by host Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Hemagglutinin Host cell membrane Host membrane Host-virus interaction ... | MKTIIALSYI | MKTIIALSYIFCLALGQDLPGNDNSTATLCLGHHAVPNGTLVKTITDDQIEVTNATELVQSSSTGKICNNPHRILDGIDCTLIDALLGDPHCDVFQNETWDLFVERSKAFSNCYPYDVPDYASLRSLVASSGTLEFITEGFTWTGVTQNGGSNACKRGPGSGFFSRLNWLTKSGSTYPVLNVTMPNNDNFDKLYIWGIHHPSTNQEQTSLYVQASGRVTVSTRRSQQTIIPNIGSRPWVRGLSSRISIYWTIVKPGDVLVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIDTCISECITPNGSIPNDKPFQNVNKITYGA... | clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane viral budding from plasma membrane virion attachment to host cell host cell plasma membrane; membrane; viral envelope; virion membrane host cell surface receptor b... |
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane viral budding from plasma membrane virion attachment to host cell | host cell plasma membrane; membrane; viral envelope; virion membrane | host cell surface receptor binding | Influenza A virus | 3D-structure Clathrin- and caveolin-independent endocytosis of virus by host Clathrin-mediated endocytosis of virus by host Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Hemagglutinin Host cell membrane Host membrane Host-virus interaction ... | MAIIYLILLF | MAIIYLILLFTAVRGDQICIGYHANNSTEKVDTNLERNVTVTHAKDILEKTHNGKLCKLNGIPPLELGDCSIAGWLLGNPECDRLLSVPEWSYIMEKENPRDGLCYPGSFNDYEELKHLLSSVKHFEKVKILPKDRWTQHTTTGGSRACAVSGNPSFFRNMVWLTKEGSDYPVAKGSYNNTSGEQMLIIWGVHHPIDETEQRTLYQNVGTYVSVGTSTLNKRSTPEIATRPKVNGQGGRMEFSWTLLDMWDTINFESTGNLIAPEYGFKISKRGSSGIMKTEGTLENCETKCQTPLGAINTTLPFHNVHPLTIGECPKYV... | clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane viral budding from plasma membrane virion attachment to host cell host cell plasma membrane; membrane; viral envelope; virion membrane host cell surface receptor b... |
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane viral budding from plasma membrane virion attachment to host cell | extracellular region; host cell plasma membrane; plasma membrane; viral envelope; virion membrane | host cell surface receptor binding | Influenza A virus | 3D-structure Clathrin- and caveolin-independent endocytosis of virus by host Clathrin-mediated endocytosis of virus by host Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Hemagglutinin Host cell membrane Host membrane Host-virus interaction ... | MKANLLVLLC | MKANLLVLLCALAAADADTICIGYHANNSTDTVDTVLEKNVTVTHSVNLLEDSHNGKLCRLKGIAPLQLGKCNIAGWLLGNPECDPLLPVRSWSYIVETPNSENGICYPGDFIDYEELREQLSSVSSFERFEIFPKESSWPNHNTNGVTAACSHEGKSSFYRNLLWLTEKEGSYPKLKNSYVNKKGKEVLVLWGIHHPPNSKEQQNLYQNENAYVSVVTSNYNRRFTPEIAERPKVRDQAGRMNYYWTLLKPGDTIIFEANGNLIAPMYAFALSRGFGSGIITSNASMHECNTKCQTPLGAINSSLPYQNIHPVTIGECP... | clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane viral budding from plasma membrane virion attachment to host cell extracellular region; host cell plasma membrane; plasma membrane; viral envelope; virion membrane... |
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane viral budding from plasma membrane virion attachment to host cell | host cell plasma membrane; membrane; viral envelope; virion membrane | host cell surface receptor binding | Influenza A virus ) | Clathrin- and caveolin-independent endocytosis of virus by host Clathrin-mediated endocytosis of virus by host Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Hemagglutinin Host cell membrane Host membrane Host-virus interaction Lipoprotein M... | MKAKLLVLLY | MKAKLLVLLYAFVATDADTICIGYHANNSTDTVDTIFEKNVAVTHSVNLLEDRHNGKLCKLKGIAPLQLGKCNITGWLLGNPECDSLLPARSWSYIVETPNSENGACYPGDFIDYEELREQLSSVSSLERFEIFPKESSWPNHTFNGVTVSCSHRGKSSFYRNLLWLTKKGDSYPKLTNSYVNNKGKEVLVLWGVHHPSSSDEQQSLYSNGNAYVSVASSNYNRRFTPEIAARPKVKDQHGRMNYYWTLLEPGDTIIFEATGNLIAPWYAFALSRGFESGIITSNASMHECNTKCQTPQGSINSNLPFQNIHPVTIGECP... | clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane viral budding from plasma membrane virion attachment to host cell host cell plasma membrane; membrane; viral envelope; virion membrane host cell surface receptor b... |
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane viral budding from plasma membrane virion attachment to host cell | host cell plasma membrane; membrane; viral envelope; virion membrane | host cell surface receptor binding | Influenza A virus | Clathrin- and caveolin-independent endocytosis of virus by host Clathrin-mediated endocytosis of virus by host Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Hemagglutinin Host cell membrane Host membrane Host-virus interaction Lipoprotein M... | MNTQILVFAL | MNTQILVFALVAVIPTNADKICLGHHAVSNGTKVNTLTERGVEVVNATETVERTNIPKICSKGKRTTDLGQCGLLGTITGPPQCDQFLEFSADLIIERREGNDVCYPGKFVNEEALRQILRGSGGIDKETMGFTYSGIRTNGTTSACRRSGSSFYAEMEWLLSNTDNASFPQMTKSYKNTRRESALIVWGIHHSGSTTEQTKLYGSGNKLITVGSSKYHQSFVPSPGTRPQINGQSGRIDFHWLILDPNDTVTFSFNGAFIAPNRASFLRGKSMGIQSDVQVDANCEGECYHSGGTITSRLPFQNINSRAVGKCPRYVKQ... | clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane viral budding from plasma membrane virion attachment to host cell host cell plasma membrane; membrane; viral envelope; virion membrane host cell surface receptor b... |
viral entry into host cell viral penetration into host nucleus | extracellular region; helical viral capsid; host cell nucleus; plasma membrane; ribonucleoprotein complex; viral nucleocapsid | identical protein binding RNA binding structural molecule activity | Influenza A virus | 3D-structure Capsid protein Helical capsid protein Host nucleus Host-virus interaction Reference proteome Ribonucleoprotein RNA-binding Viral nucleoprotein Viral penetration into host nucleus Virion Virus entry into host cell | MASQGTKRSY | MASQGTKRSYEQMETDGERQNATEIRASVGKMIGGIGRFYIQMCTELKLSDYEGRLIQNSLTIERMVLSAFDERRNKYLEEHPSAGKDPKKTGGPIYRRVNGKWMRELILYDKEEIRRIWRQANNGDDATAGLTHMMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMVMELVRMIKRGINDRNFWRGENGRKTRIAYERMCNILKGKFQTAAQKAMMDQVRESRNPGNAEFEDLTFLARSALILRGSVAHKSCLPACVYGPAVASGYDFEREGYSLVGIDPFRLLQNSQVYSLIRPNE... | viral entry into host cell viral penetration into host nucleus extracellular region; helical viral capsid; host cell nucleus; plasma membrane; ribonucleoprotein complex; viral nucleocapsid identical protein binding RNA binding structural molecule activity Influenza A virus 3D-structure Capsid protein Helical capsid pro... |
carbohydrate metabolic process immune response viral budding from plasma membrane viral release from host cell | extracellular region; host cell plasma membrane; plasma membrane; virion membrane | exo-alpha-(2->3)-sialidase activity exo-alpha-(2->6)-sialidase activity exo-alpha-(2->8)-sialidase activity exo-alpha-sialidase activity metal ion binding peptidase activator activity | Influenza A virus | 3D-structure Calcium Disulfide bond Glycoprotein Glycosidase Host cell membrane Host membrane Hydrolase Membrane Metal-binding Reference proteome Signal-anchor Transmembrane Transmembrane helix Virion | MNPNQKIITI | MNPNQKIITIGSICLVVGLISLILQIGNIISIWISHSIQTGSQNHTGICNQNIITYKNSTWVKDTTSVILTGNSSLCPIRGWAIYSKDNSIRIGSKGDVFVIREPFISCSHLECRTFFLTQGALLNDKHSNGTVKDRSPYRALMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGISGPDNGAVAVLKYNGIITETIKSWRKKILRTQESECACVNGSCFTIMTDGPSDGLASYKIFKIEKGKVTKSIELNAPNSHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYQIGYICSGVFGDNPRPEDGTGSC... | carbohydrate metabolic process immune response viral budding from plasma membrane viral release from host cell extracellular region; host cell plasma membrane; plasma membrane; virion membrane exo-alpha-(2->3)-sialidase activity exo-alpha-(2->6)-sialidase activity exo-alpha-(2->8)-sialidase activity exo-alpha-sialidase... |
carbohydrate metabolic process viral budding from plasma membrane | host cell plasma membrane; membrane; virion membrane | exo-alpha-(2->3)-sialidase activity exo-alpha-(2->6)-sialidase activity exo-alpha-(2->8)-sialidase activity metal ion binding | Influenza A virus ) | Calcium Disulfide bond Glycoprotein Glycosidase Host cell membrane Host membrane Hydrolase Membrane Metal-binding Reference proteome Signal-anchor Transmembrane Transmembrane helix Virion | MNPNQKIITI | MNPNQKIITIGSICMVVGIISLILQIGNIISIWISHSIQTGNQNHTGICNQGIITYNVVAGQDSTSVILTGNSSLCPIRGWAIHSKDNGIRIGSKGDVFVIREPFISCSHLECRTFFLTQGALLNDKHSNGTVKDRSPYRALMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGISGPDNGAVAVLKYNGIITETIKSWRKKILRTQESECTCVNGSCFTIMTDGPSNGLASYKIFKIEKGKVTKSIELNAPNSHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYQIGYICSGVFGDNPRPKDGPGSCG... | carbohydrate metabolic process viral budding from plasma membrane host cell plasma membrane; membrane; virion membrane exo-alpha-(2->3)-sialidase activity exo-alpha-(2->6)-sialidase activity exo-alpha-(2->8)-sialidase activity metal ion binding Influenza A virus )Calcium Disulfide bond Glycoprotein Glycosidase Host ce... |
carbohydrate metabolic process viral budding from plasma membrane | host cell plasma membrane; membrane; virion membrane | exo-alpha-(2->3)-sialidase activity exo-alpha-(2->6)-sialidase activity exo-alpha-(2->8)-sialidase activity metal ion binding | Influenza A virus | 3D-structure Calcium Disulfide bond Glycoprotein Glycosidase Host cell membrane Host membrane Hydrolase Membrane Metal-binding Signal-anchor Transmembrane Transmembrane helix Virion | MNPNQKILCT | MNPNQKILCTSATALVIGTIAVLIGITNLGLNIGLHLKPSCNCSHSQPEATNASQTIINNYYNDTNITQISNTNIQVEERAIRDFNNLTKGLCTINSWHIYGKDNAVRIGEDSDVLVTREPYVSCDPDECRFYALSQGTTIRGKHSNGTIHDRSQYRALISWPLSSPPTVYNSRVECIGWSSTSCHDGKTRMSICISGPNNNASAVIWYNRRPVTEINTWARNILRTQESECVCHNGVCPVVFTDGSATGPAETRIYYFKEGKILKWEPLAGTAKHIEECSCYGERAEITCTCRDNWQGSNRPVIRIDPVAMTHTSQYIC... | carbohydrate metabolic process viral budding from plasma membrane host cell plasma membrane; membrane; virion membrane exo-alpha-(2->3)-sialidase activity exo-alpha-(2->6)-sialidase activity exo-alpha-(2->8)-sialidase activity metal ion binding Influenza A virus 3D-structure Calcium Disulfide bond Glycoprotein Glycosid... |
carbohydrate metabolic process viral budding from plasma membrane | host cell plasma membrane; membrane; virion membrane | exo-alpha-(2->3)-sialidase activity exo-alpha-(2->6)-sialidase activity exo-alpha-(2->8)-sialidase activity metal ion binding | Influenza B virus | 3D-structure Calcium Disulfide bond Glycoprotein Glycosidase Host cell membrane Host membrane Hydrolase Membrane Metal-binding Reference proteome Signal-anchor Transmembrane Transmembrane helix Virion | MLPSTVQTLT | MLPSTVQTLTLLLTSGGVLLSLYVSASLSYLLYSDVLLKFSSTKTTAPTMSLECTNASNAQTVNHSATKEMTFPPPEPEWTYPRLSCQGSTFQKALLISPHRFGEIKGNSAPLIIREPFVACGPKECRHFALTHYAAQPGGYYNGTRKDRNKLRHLVSVKLGKIPTVENSIFHMAAWSGSACHDGREWTYIGVDGPDNDALVKIKYGEAYTDTYHSYAHNILRTQESACNCIGGDCYLMITDGSASGISKCRFLKIREGRIIKEILPTGRVEHTEECTCGFASNKTIECACRDNSYTAKRPFVKLNVETDTAEIRLMCTK... | carbohydrate metabolic process viral budding from plasma membrane host cell plasma membrane; membrane; virion membrane exo-alpha-(2->3)-sialidase activity exo-alpha-(2->6)-sialidase activity exo-alpha-(2->8)-sialidase activity metal ion binding Influenza B virus 3D-structure Calcium Disulfide bond Glycoprotein Glycosid... |
viral budding from plasma membrane | extracellular region; host cell nucleus; plasma membrane; virion membrane | RNA binding structural constituent of virion | Influenza A virus | 3D-structure Alternative splicing Host nucleus Membrane Reference proteome RNA-binding Viral matrix protein Virion | MSLLTEVETY | MSLLTEVETYVLSIIPSGPLKAEIAQRLEDVFAGKNTDLEVLMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDKAVKLYRKLKREITFHGAKEISLSYSAGALASCMGLIYNRMGAVTTEVAFGLVCATCEQIADSQHRSHRQMVTTTNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVASQARQMVQAMRTIGTHPSSSAGLKNDLLENLQAYQKRMGVQMQRFK | viral budding from plasma membrane extracellular region; host cell nucleus; plasma membrane; virion membrane RNA binding structural constituent of virion Influenza A virus 3D-structure Alternative splicing Host nucleus Membrane Reference proteome RNA-binding Viral matrix protein Virion MSLLTEVETY MSLLTEVETYVLSIIPSGPLKA... |
protein complex oligomerization suppression by virus of host autophagy virus-mediated pore formation in host cell membrane | host cell plasma membrane; membrane; virion membrane | monoatomic ion channel activity proton transmembrane transporter activity | Influenza A virus | Alternative splicing Disulfide bond Glycoprotein Host cell membrane Host membrane Host-virus interaction Hydrogen ion transport Inhibition of host autophagy by virus Ion channel Ion transport Lipoprotein Membrane Palmitate Phosphoprotein Signal-anchor Transmembrane Transmembrane helix Transport Viral ion channel Virion | MSLLTEVETP | MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGILHLILWILDRLFFKCIYRFFKHGLKRGPSTEGVPESMREEYRKEQQNAVDADDSHFVSIELE | protein complex oligomerization suppression by virus of host autophagy virus-mediated pore formation in host cell membrane host cell plasma membrane; membrane; virion membrane monoatomic ion channel activity proton transmembrane transporter activity Influenza A virus Alternative splicing Disulfide bond Glycoprotein Hos... |
protein complex oligomerization suppression by virus of host autophagy virus-mediated pore formation in host cell membrane | host cell plasma membrane; membrane; virion membrane | monoatomic ion channel activity proton transmembrane transporter activity | Influenza A virus | Alternative splicing Disulfide bond Glycoprotein Host cell membrane Host membrane Host-virus interaction Hydrogen ion transport Inhibition of host autophagy by virus Ion channel Ion transport Lipoprotein Membrane Palmitate Phosphoprotein Signal-anchor Transmembrane Transmembrane helix Transport Viral ion channel Virion | MSLLTEVETP | MSLLTEVETPTRNGWECRCNDSSDPLIIAASIIGILHLILWILNRLFFKCIYRRLKYGLKRGPSTEGVPESMREEYRQEQQSAVDVDDGHFVNIELE | protein complex oligomerization suppression by virus of host autophagy virus-mediated pore formation in host cell membrane host cell plasma membrane; membrane; virion membrane monoatomic ion channel activity proton transmembrane transporter activity Influenza A virus Alternative splicing Disulfide bond Glycoprotein Hos... |
modulation by symbiont of host intracellular transport modulation by virus of host transcription suppression by virus of host cytokine production suppression by virus of host mRNA processing suppression by virus of host PKR signaling suppression by virus of host type I interferon-mediated signaling pathway suppression ... | host cell cytoplasm; host cell nucleus | double-stranded RNA binding identical protein binding protein serine/threonine kinase inhibitor activity | Influenza A virus | 3D-structure Alternative splicing Eukaryotic host gene expression shutoff by virus Host cytoplasm Host gene expression shutoff by virus Host mRNA suppression by virus Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Inhibitio... | MDSNTVSSFQ | MDSNTVSSFQVDCFLWHVRKQVVDQELGDAPFLDRLRRDQKSLRGRGSTLGLNIEAATHVGKQIVEKILKEESDEALKMTMASTPASRYITDMTIEELSRDWFMLMPKQKVEGPLCIRIDQAIMDKNIMLKANFSVIFDRLETLILLRAFTEEGAIVGEISPLPSFPGHTIEDVKNAIGVLIGGLEWNDNTVRVSKTLQRFAWGSSNENGRPPLTPKQKRKMARTARSKVRRDKMAD | modulation by symbiont of host intracellular transport modulation by virus of host transcription suppression by virus of host cytokine production suppression by virus of host mRNA processing suppression by virus of host PKR signaling suppression by virus of host type I interferon-mediated signaling pathway suppression ... |
suppression by virus of host mRNA processing suppression by virus of host PKR signaling suppression by virus of host type I interferon-mediated signaling pathway suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity | host cell cytoplasm; host cell nucleus | identical protein binding protein serine/threonine kinase inhibitor activity RNA binding | Influenza A virus | 3D-structure Alternative splicing Eukaryotic host gene expression shutoff by virus Host cytoplasm Host gene expression shutoff by virus Host mRNA suppression by virus Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Inhibitio... | MDPNTVSSFQ | MDPNTVSSFQVDCFLWHVRKRVADQELGDAPFLDRLRRDQKSLRGRGSTLGLDIETATRAGKQIVERILKEESDEALKMTMASVPASRYLTDMTLEEMSRDWSMLIPKQKVAGPLCIRMDQAIMDKNIILKANFSVIFDRLETLILLRAFTEEGAIVGEISPLPSLPGHTAEDVKNAVGVLIGGLEWNDNTVRVSETLQRFAWRSSNENGRPPLTPKQKREMAGTIRSEV | suppression by virus of host mRNA processing suppression by virus of host PKR signaling suppression by virus of host type I interferon-mediated signaling pathway suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity host cell cytoplas... |
suppression by virus of host ISG15-protein conjugation suppression by virus of host PKR signaling suppression by virus of host type I interferon-mediated signaling pathway | host cell cytoplasm; host cell nucleus | protein serine/threonine kinase inhibitor activity RNA binding | Influenza B virus | 3D-structure Alternative splicing Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Inhibition of host ISG15 by virus Inhibition of host PKR by virus Interferon antiviral system evasion Reference proteome RNA-bi... | MADNMTTTQI | MADNMTTTQIEVGPGATNATINFEAGILECYERFSWQRALDYPGQDRLHRLKRKLESRIKTHNKSEPENKRMSLEERKAIGVKMMKVLLFMDPSAGIEGFEPYCVKNPSTSKCPNYDWTDYPPTPGKYLDDIEEEPENVDHPIEVVLRDMNNKDARQKIKDEVNTQKEGKFRLTIKRDIRNVLSLRVLVNGTFLKHPNGDKSLSTLHRLNAYDQNGGLVAKLVATDDRTVEDEKDGHRILNSLFERFDEGHSKPIRAAETAVGVLSQFGQEHRLSPEEGDN | suppression by virus of host ISG15-protein conjugation suppression by virus of host PKR signaling suppression by virus of host type I interferon-mediated signaling pathway host cell cytoplasm; host cell nucleus protein serine/threonine kinase inhibitor activity RNA binding Influenza B virus 3D-structure Alternative spl... |
phosphorylation suppression by virus of host mRNA export from nucleus suppression by virus of host transcription initiation from RNA polymerase II promoter viral budding via host ESCRT complex | host cell cytoplasm; host cell nuclear membrane; membrane; viral envelope; virion membrane | structural constituent of virion | Vesicular stomatitis Indiana virus | 3D-structure Alternative initiation Apoptosis Eukaryotic host gene expression shutoff by virus Host cytoplasm Host gene expression shutoff by virus Host membrane Host mRNA suppression by virus Host nucleus Host-virus interaction Inhibition of host mRNA nuclear export by virus Membrane Phosphoprotein Reference proteome ... | MSSLKKILGL | MSSLKKILGLKGKGKKSKKLGIAPPPYEEDTSMEYAPSAPIDKSYFGVDEMDTYDPNQLRYEKFFFTVKMTVRSNRPFRTYSDVAAAVSHWDHMYIGMAGKRPFYKILAFLGSSNLKATPAVLADQGQPEYHTHCEGRAYLPHRMGKTPPMLNVPEHFRRPFNIGLYKGTIELTMTIYDDESLEAAPMIWDHFNSSKFSDFREKALMFGLIVEKKASGAWVLDSISHFK | phosphorylation suppression by virus of host mRNA export from nucleus suppression by virus of host transcription initiation from RNA polymerase II promoter viral budding via host ESCRT complex host cell cytoplasm; host cell nuclear membrane; membrane; viral envelope; virion membrane structural constituent of virion Ves... |
phosphorylation viral genome replication viral transcription | host cell cytoplasm; virion component | RNA folding chaperone RNA-dependent RNA polymerase activity | Vesicular stomatitis Indiana virus | 3D-structure Chaperone Host cytoplasm Phosphoprotein Reference proteome Viral RNA replication Viral transcription Virion | MDNLTKVREY | MDNLTKVREYLKSYSRLDQAVGEIDEIEAQRAEKSNYELFQEDGVEEHTKPSYFQAADDSDTESEPEIEDNQGLYAQDPEAEQVEGFIQGPLDDYADEEVDVVFTSDWKPPELESDEHGKTLRLTSPEGLSGEQKSQWLSTIKAVVQSAKYWNLAECTFEASGEGVIMKERQITPDVYKVTPVMNTHPSQSEAVSDVWSLSKTSMTFQPKKASLQPLTISLDELFSSRGEFISVGGDGRMSHKEAILLGLRYKKLYNQARVKYSL | phosphorylation viral genome replication viral transcription host cell cytoplasm; virion component RNA folding chaperone RNA-dependent RNA polymerase activity Vesicular stomatitis Indiana virus 3D-structure Chaperone Host cytoplasm Phosphoprotein Reference proteome Viral RNA replication Viral transcription Virion MDNL... |
receptor-mediated virion attachment to host cell | host cell endoplasmic reticulum lumen; T=13 icosahedral viral capsid; viral outer capsid | metal ion binding | Rotavirus A ) | Alternative initiation Calcium Capsid protein Disulfide bond Glycoprotein Host endoplasmic reticulum Host-virus interaction Metal-binding Outer capsid protein Reference proteome Signal T=13 icosahedral capsid protein Virion | MYGIEYTTVL | MYGIEYTTVLTFLISIILLNYILKSLTRIMDCIIYRLLFIIVILSPFLRAQNYGINLPITGSMDTAYANSTQEETFLTSTLCLYYPTEAATEINDNSWKDTLSQLFLTKGWPTGSVYFKEYTNIASFSVDPQLYCDYNVVLMKYDATLQLDMSELADLILNEWLCNPMDITLYYYQQTDEANKWISMGSSCTIKVCPLNTQTLGIGCLTTDATTFEEVATAEKLVITDVVDGVNHKLDVTTATCTIRNCKKLGPRENVAVIQVGGSDILDITADPTTAPQTERMMRINWKKWWQVFYTVVDYVDQIIQVMSKRSRSLNSA... | receptor-mediated virion attachment to host cell host cell endoplasmic reticulum lumen; T=13 icosahedral viral capsid; viral outer capsid metal ion binding Rotavirus A )Alternative initiation Calcium Capsid protein Disulfide bond Glycoprotein Host endoplasmic reticulum Host-virus interaction Metal-binding Outer capsi... |
fusion of virus membrane with host endosome membrane receptor-mediated endocytosis of virus by host cell virion attachment to host cell | host cell endoplasmic reticulum membrane; host cell Golgi membrane; host cell plasma membrane; membrane; viral envelope; virion membrane | metal ion binding | Pichinde mammarenavirus | Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endoplasmic reticulum Host Golgi apparatus Host membrane Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Reference proteome Transmembrane Transmembran... | MGQIVTLIQS | MGQIVTLIQSIPEVLQEVFNVALIIVSVLCIVKGFVNLMRCGLFQLVTFLILSGRSCDSMMIDRRHNLTHVEFNLTRMFDNLPQSCSKNNTHHYYKGPSNTTWGIELTLTNTSIANETSGNFSNIGSLGYGNISNCDRTREAGHTLKWLLNELHFNVLHVTRHIGARCKTVEGAGVLIQYNLTVGDRGGEVGRHLIASLAQIIGDPKIAWVGKCFNNCSGDTCRLTNCEGGTHYNFLIIQNTTWENHCTYTPMATIRMALQRTAYSSVSRKLLGFFTWDLSDSSGQHVPGGYCLEQWAIIWAGIKCFDNTVMAKCNKDHN... | fusion of virus membrane with host endosome membrane receptor-mediated endocytosis of virus by host cell virion attachment to host cell host cell endoplasmic reticulum membrane; host cell Golgi membrane; host cell plasma membrane; membrane; viral envelope; virion membrane metal ion binding Pichinde mammarenavirus Disu... |
DNA replication rolling circle single-stranded viral DNA replication | host cell nucleus | ATP binding DNA binding endodeoxyribonuclease activity, producing 5'-phosphomonoesters helicase activity metal ion binding nucleotidyltransferase activity structural molecule activity | Tomato golden mosaic virus | ATP-binding Covalent protein-DNA linkage DNA replication DNA-binding Endonuclease Helicase Host nucleus Host-virus interaction Hydrolase Metal-binding Multifunctional enzyme Nuclease Nucleotide-binding Nucleotidyltransferase Reference proteome Transferase | MPSHPKRFQI | MPSHPKRFQINAKNYFLTYPQCSLSKEESLSQLQALNTPINKKFIKICRELHEDGQPHLHVLIQFEGKYCCQNQRFFDLVSPTRSAHFHPNIQRAKSSSDVKTYIDKDGDTLVWGEFQVDGRSARGGCQTSNDAAAEALNASSKEEALQIIREKIPEKYLFQFHNLNSNLDRIFDKTPEPWLPPFHVSSFTNVPDEMRQWAENYFGKSSAARPERPISIIIEGDSRTGKTMWARSLGPHNYLSGHLDLNSRVYSNKVEYNVIDDVTPQYLKLKHWKELIGAQRDWQTNCKYGKPVQIKGGIPSIVLCNPGEGASYKVFLD... | DNA replication rolling circle single-stranded viral DNA replication host cell nucleus ATP binding DNA binding endodeoxyribonuclease activity, producing 5'-phosphomonoesters helicase activity metal ion binding nucleotidyltransferase activity structural molecule activity Tomato golden mosaic virus ATP-binding Covalent ... |
positive stranded viral RNA replication RNA processing | host cell cytoplasm; host cell endoplasmic reticulum membrane; membrane | ATP binding helicase activity hydrolase activity, acting on acid anhydrides mRNA methyltransferase activity RNA binding | Brome mosaic virus | ATP-binding Helicase Host endoplasmic reticulum Host membrane Hydrolase Membrane Methyltransferase Nucleotide-binding Reference proteome Transferase | MSSSIDLLKL | MSSSIDLLKLIAEKGADSQSAQDIVDNQVAQQLSAQIEYAKRSKKINVRNKLSIEEADAFRDRYGGAFDLNLTQQYHAPHSLAGALRVAEHYDCLDSFPPEDPVIDFGGSWWHHFSRRDKRVHSCCPVLGVRDAARHEERMCRMRKILQESDDFDEVPNFCLNRAQDCDVQADWAICIHGGYDMGFQGLCDAMHSHGVRVLRGTVMFDGAMLFDREGFLPLLKCHWQRDGSGADEVIKFDFENESTLSYIHGWQDLGSFFTESVHCIDGTTYLLEREMLKCNIMTYKIIATNLRCPRETLRHCVWFEDISKYVGVSIPED... | positive stranded viral RNA replication RNA processing host cell cytoplasm; host cell endoplasmic reticulum membrane; membrane ATP binding helicase activity hydrolase activity, acting on acid anhydrides mRNA methyltransferase activity RNA binding Brome mosaic virus ATP-binding Helicase Host endoplasmic reticulum Host m... |
negative regulation of viral translation regulation of translation | T=3 icosahedral viral capsid | identical protein binding RNA binding structural molecule activity | Escherichia phage MS2 | 3D-structure Capsid protein Reference proteome RNA-binding T=3 icosahedral capsid protein Translation regulation Virion | MASNFTQFVL | MASNFTQFVLVDNGGTGDVTVAPSNFANGVAEWISSNSRSQAYKVTCSVRQSSAQNRKYTIKVEVPKVATQTVGGVELPVAAWRSYLNMELTIPIFATNSDCELIVKAMQGLLKDGNPIPSAIAANSGIY | negative regulation of viral translation regulation of translation T=3 icosahedral viral capsid identical protein binding RNA binding structural molecule activity Escherichia phage MS2 3D-structure Capsid protein Reference proteome RNA-binding T=3 icosahedral capsid protein Translation regulation Virion MASNFTQFVL MASN... |
regulation of translation | T=3 icosahedral viral capsid | identical protein binding RNA binding | Pseudomonas phage PP7 | 3D-structure Capsid protein Direct protein sequencing Disulfide bond Reference proteome RNA-binding T=3 icosahedral capsid protein Translation regulation Virion | MSKTIVLSVG | MSKTIVLSVGEATRTLTEIQSTADRQIFEEKVGPLVGRLRLTASLRQNGAKTAYRVNLKLDQADVVDCSTSVCGELPKVRYTQVWSHDVTIVANSTEASRKSLYDLTKSLVATSQVEDLVVNLVPLGR | regulation of translation T=3 icosahedral viral capsid identical protein binding RNA binding Pseudomonas phage PP7 3D-structure Capsid protein Direct protein sequencing Disulfide bond Reference proteome RNA-binding T=3 icosahedral capsid protein Translation regulation Virion MSKTIVLSVG MSKTIVLSVGEATRTLTEIQSTADRQIFEEKVG... |
DNA replication viral DNA genome replication | host cell membrane; membrane | RNA binding | Bacillus phage phi29 | Alternative initiation Coiled coil Direct protein sequencing DNA replication Early protein Host membrane Membrane Reference proteome RNA-binding Viral DNA replication | MGKIFDQEKR | MGKIFDQEKRLEGTWKNSKWGNQGIIAPVDGDLKMIDLELEKKMTKLEHENKLMKNALYELSRMENNDYATWVIKVLFGGAPHGAK | DNA replication viral DNA genome replication host cell membrane; membrane RNA binding Bacillus phage phi29 Alternative initiation Coiled coil Direct protein sequencing DNA replication Early protein Host membrane Membrane Reference proteome RNA-binding Viral DNA replication MGKIFDQEKR MGKIFDQEKRLEGTWKNSKWGNQGIIAPVDGDLKM... |
disruption by virus of host cell wall peptidoglycan during virus entry disruption of host cell envelope during viral entry DNA replication, synthesis of RNA primer viral DNA genome packaging viral DNA genome replication | host cell nucleus; viral terminase complex; virion component | DNA binding hydrolase activity | Bacillus phage phi29 | 3D-structure Coiled coil Covalent protein-DNA linkage Degradation of host cell envelope components during virus entry Degradation of host peptidoglycans during virus entry DNA replication DNA-binding Early protein Host nucleus Hydrolase Phosphoprotein Reference proteome Viral DNA replication Viral genome packaging Vira... | MARSPRIRIK | MARSPRIRIKDNDKAEYARLVKNTKAKIARTKKKYGVDLTAEIDIPDLDSFETRAQFNKWKEQASSFTNRANMRYQFEKNAYGVVASKAKIAEIERNTKEVQRLVDEKIKAMKDKEYYAGGKPQGTIEQRIAMTSPAHVTGINRPHDFDFSKVRSYSRLRTLEESMEMRTDPQYYEKKMIQLQLNFIKSVEGSFNSFDAADELIEELKKIPPDDFYELFLRISEISFEEFDSEGNTVENVEGNVYKILSYLEQYRRGDFDLSLKGF | disruption by virus of host cell wall peptidoglycan during virus entry disruption of host cell envelope during viral entry DNA replication, synthesis of RNA primer viral DNA genome packaging viral DNA genome replication host cell nucleus; viral terminase complex; virion component DNA binding hydrolase activity Bacillus... |
chromosome condensation DNA replication DNA-templated transcription regulation of viral transcription viral DNA genome replication | transcription repressor complex | DNA binding DNA-binding transcription repressor activity | Bacillus phage phi29 | DNA condensation DNA replication DNA-binding Early protein Reference proteome Repressor Transcription Transcription regulation Viral DNA replication | MAKMMQREIT | MAKMMQREITKTTVNVAKMVMVDGEVQVEQLPSETFVGNLTMEQAQWRMKRKYKGEPVQVVSVEPNTEVYELPVEKFLEVATVRVEKDEDQEEQTEAPEEQVAE | chromosome condensation DNA replication DNA-templated transcription regulation of viral transcription viral DNA genome replication transcription repressor complex DNA binding DNA-binding transcription repressor activity Bacillus phage phi29 DNA condensation DNA replication DNA-binding Early protein Reference proteome R... |
negative regulation of cytolysis viral release from host cell by cytolysis | host cell plasma membrane; membrane | pore-forming activity | Escherichia phage lambda | Alternative initiation Cytolysis Formylation Host cell inner membrane Host cell lysis by virus Host cell membrane Host membrane Late protein Membrane Reference proteome Transmembrane Transmembrane helix Viral release from host cell | MKMPEKHDLL | MKMPEKHDLLAAILAAKEQGIGAILAFAMAYLRGRYNGGAFTKTVIDATMCAIIAWFIRDLLDFAGLSSNLAYITSVFIGYIGTDSIGSLIKRFAAKKAGVEDGRNQ | negative regulation of cytolysis viral release from host cell by cytolysis host cell plasma membrane; membrane pore-forming activity Escherichia phage lambda Alternative initiation Cytolysis Formylation Host cell inner membrane Host cell lysis by virus Host cell membrane Host membrane Late protein Membrane Reference pr... |
cell wall macromolecule catabolic process defense response to bacterium peptidoglycan catabolic process viral release from host cell by cytolysis | host cell cytoplasm | lysozyme activity lytic transglycosylase activity | Escherichia phage lambda | 3D-structure Antimicrobial Bacteriolytic enzyme Cytolysis Direct protein sequencing Host cell lysis by virus Host cytoplasm Lyase Reference proteome Viral release from host cell | MVEINNQRKA | MVEINNQRKAFLDMLAWSEGTDNGRQKTRNHGYDVIVGGELFTDYSDHPRKLVTLNPKLKSTGAGRYQLLSRWWDAYRKQLGLKDFSPKSQDAVALQQIKERGALPMIDRGDIRQAIDRCSNIWASLPGAGYGQFEHKADSLIAKFKEAGGTVREIDV | cell wall macromolecule catabolic process defense response to bacterium peptidoglycan catabolic process viral release from host cell by cytolysis host cell cytoplasm lysozyme activity lytic transglycosylase activity Escherichia phage lambda 3D-structure Antimicrobial Bacteriolytic enzyme Cytolysis Direct protein sequen... |
viral DNA genome packaging | host cell cytoplasm; viral terminase, small subunit | ATP binding ATP hydrolysis activity sequence-specific DNA binding, bending | Escherichia phage lambda | 3D-structure ATP-binding Coiled coil Direct protein sequencing DNA-binding Host cytoplasm Hydrolase Nucleotide-binding Reference proteome Viral genome packaging Viral release from host cell | MEVNKKQLAD | MEVNKKQLADIFGASIRTIQNWQEQGMPVLRGGGKGNEVLYDSAAVIKWYAERDAEIENEKLRREVEELRQASEADLQPGTIEYERHRLTRAQADAQELKNARDSAEVVETAFCTFVLSRIAGEIASILDGLPLSVQRRFPELENRHVDFLKRDIIKAMNKAAALDELIPGLLSEYIEQSG | viral DNA genome packaging host cell cytoplasm; viral terminase, small subunit ATP binding ATP hydrolysis activity sequence-specific DNA binding, bending Escherichia phage lambda 3D-structure ATP-binding Coiled coil Direct protein sequencing DNA-binding Host cytoplasm Hydrolase Nucleotide-binding Reference proteome Vir... |
viral DNA genome packaging | host cell cytoplasm; viral terminase, large subunit | ATP binding ATP hydrolysis activity DNA helicase activity endonuclease activity metal ion binding type II site-specific deoxyribonuclease activity | Escherichia phage lambda | ATP-binding Direct protein sequencing Endonuclease Host cytoplasm Hydrolase Magnesium Metal-binding Nuclease Nucleotide-binding Reference proteome Viral genome packaging Viral release from host cell | MNISNSQVNR | MNISNSQVNRLRHFVRAGLRSLFRPEPQTAVEWADANYYLPKESAYQEGRWETLPFQRAIMNAMGSDYIREVNVVKSARVGYSKMLLGVYAYFIEHKQRNTLIWLPTDGDAENFMKTHVEPTIRDIPSLLALAPWYGKKHRDNTLTMKRFTNGRGFWCLGGKAAKNYREKSVDVAGYDELAAFDDDIEQEGSPTFLGDKRIEGSVWPKSIRGSTPKVRGTCQIERAASESPHFMRFHVACPHCGEEQYLKFGDKETPFGLKWTPDDPSSVFYLCEHNACVIRQQELDFTDARYICEKTGIWTRDGILWFSSSGEEIEPPD... | viral DNA genome packaging host cell cytoplasm; viral terminase, large subunit ATP binding ATP hydrolysis activity DNA helicase activity endonuclease activity metal ion binding type II site-specific deoxyribonuclease activity Escherichia phage lambda ATP-binding Direct protein sequencing Endonuclease Host cytoplasm Hyd... |
proteolysis viral procapsid maturation | host cell cytoplasm; viral capsid | identical protein binding serine-type peptidase activity | Escherichia phage lambda | Alternative initiation Capsid protein Host cytoplasm Hydrolase Protease Reference proteome Serine protease Viral capsid assembly Viral capsid maturation Viral release from host cell Virion | MTAELRNLPH | MTAELRNLPHIASMAFNEPLMLEPAYARVFFCALAGQLGISSLTDAVSGDSLTAQEALATLALSGDDDGPRQARSYQVMNGIAVLPVSGTLVSRTRALQPYSGMTGYNGIIARLQQAASDPMVDGILLDMDTPGGMVAGAFDCADIIARVRDIKPVWALANDMNCSAGQLLASAASRRLVTQTARTGSIGVMMAHSNYGAALEKQGVEITLIYSGSHKVDGNPYSHLPDDVRETLQSRMDATRQMFAQKVSAYTGLSVQVVLDTEAAVYSGQEAIDAGLADELVNSTDAITVMRDALDARKSRLSGGRMTKETQSTTVSA... | proteolysis viral procapsid maturation host cell cytoplasm; viral capsid identical protein binding serine-type peptidase activity Escherichia phage lambda Alternative initiation Capsid protein Host cytoplasm Hydrolase Protease Reference proteome Serine protease Viral capsid assembly Viral capsid maturation Viral releas... |
DNA integration DNA replication DNA transposition viral DNA genome replication | host cell cytoplasm | ATP binding ATP hydrolysis activity DNA binding metal ion binding | Escherichia phage Mu | 3D-structure ATP-binding DNA integration DNA replication DNA-binding Early protein Host cytoplasm Hydrolase Magnesium Metal-binding Nucleotide-binding Reference proteome Transposition Viral DNA replication | MNISDIRAGL | MNISDIRAGLRTLVENEETTFKQIALESGLSTGTISSFINDKYNGDNERVSQMLQRWLEKYHAVAELPEPPRFVETQTVKQIWTSMRFASLTESIAVVCGNPGVGKTEAAREYRRTNNNVWMITITPSCASVLECLTELAFELGMNDAPRRKGPLSRALRRRLEGTQGLVIIDEADHLGAEVLEELRLLQESTRIGLVLMGNHRVYSNMTGGNRTVEFARLFSRIAKRTAINKTKKADVKAIADAWQINGEKELELLQQIAQKPGALRILNHSLRLAAMTAHGKGERVNEDYLRQAFRELDLDVDISTLLRN | DNA integration DNA replication DNA transposition viral DNA genome replication host cell cytoplasm ATP binding ATP hydrolysis activity DNA binding metal ion binding Escherichia phage Mu 3D-structure ATP-binding DNA integration DNA replication DNA-binding Early protein Host cytoplasm Hydrolase Magnesium Metal-binding Nu... |
intracellular pH elevation potassium ion transport proton transmembrane transport regulation of intracellular pH regulation of pH response to hydrogen peroxide response to methylglyoxal response to toxic substance | membrane; plasma membrane; potassium:proton antiporter complex | antiporter activity enzyme binding glutathione-regulated potassium exporter activity nucleotide binding protein homodimerization activity toxic substance binding | Escherichia coli | 3D-structure Antiport Cell inner membrane Cell membrane Ion transport Membrane Nucleotide-binding Potassium Potassium transport Reference proteome Transmembrane Transmembrane helix Transport | MDSHTLIQAL | MDSHTLIQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPWGLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLWKLRAAVFGCGALQMVICGGLLGLFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLMVTQMGRSAFAVLLFQDIAAIPLVAMIPLLATSSASTTMGAFALSALKVAGALVLVVLLGRYVTRPALRFVARSGLREVFSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLFFIGVGMSIDFGTLLENPLRIVILLLGFLIIKIAMLWLIARPLQV... | intracellular pH elevation potassium ion transport proton transmembrane transport regulation of intracellular pH regulation of pH response to hydrogen peroxide response to methylglyoxal response to toxic substance membrane; plasma membrane; potassium:proton antiporter complex antiporter activity enzyme binding glutathi... |
2-micrometer plasmid partitioning protein localization | nucleus | identical protein binding | Saccharomyces cerevisiae | Nucleus Plasmid Plasmid partition Reference proteome | MNGERLLACI | MNGERLLACIKQCIMQHFQPMVYDESRCVIETTRGTFPVPDNYKKYKTLAFAFVGHVLNTDDTPVIEKELDWPDPALVYNTIVDRIINHPELSQFISVAFISQLKATIGEGLDINVKGTLNRRGKGIRRPKGVFFRYMESPFVNTKVTAFFSYLRDYNKIASEYHNNTKFILTFSCQAYWASGPNFSALKNVIRCSIIHEYISKFVEREQDKGHIGDQELPPEEDPSRELNNVQHEVNSLTEQDAEADEGLWGEIDSLCEKWQSEAEDQTEAEIIADRIIGNSQRMANLKIRRTKFKSVLYHILKELIQSQGTVKVYRGS... | 2-micrometer plasmid partitioning protein localization nucleus identical protein binding Saccharomyces cerevisiae Nucleus Plasmid Plasmid partition Reference proteome MNGERLLACI MNGERLLACIKQCIMQHFQPMVYDESRCVIETTRGTFPVPDNYKKYKTLAFAFVGHVLNTDDTPVIEKELDWPDPALVYNTIVDRIINHPELSQFISVAFISQLKATIGEGLDINVKGTLNRRGKGIRRPKGVFFRYMESP... |
mitochondrial electron transport, ubiquinol to cytochrome c mRNA processing proton transmembrane transport RNA splicing | mitochondrial inner membrane; mitochondrion | electron transfer activity endonuclease activity nuclease activity | Saccharomyces cerevisiae | Membrane Mitochondrion Mitochondrion inner membrane mRNA processing mRNA splicing Reference proteome Transmembrane Transmembrane helix | MAFRKSNVYL | MAFRKSNVYLSLVNSYIIDSPQPSSINYWWNMGSLLGLCLVIQIVTGIFMAMHYSSNIELAFSSVEHIMRDVHNGYILRYLHANGASFFFMVMFMHMAKGLYYGSYRSPRVTLWNVGVIIFILTIATAFLGYCCVYGQMSHWGNMNIASNMFNMMKTIYMMMLMLLIYIFYTIMMRQMMKTKEYTMLIKSMDYINKNKYMINLNMTNKKDMNNNIGPLNMNILSIIYGSMLGDGHAEKRKGGKGTRIVFQQEYCNINYLYYLHSLLANLGYCNTNLPLIKTRLGKKGKIRQYLKFNTWTYDSFNMIYSEWYIKNMSGKGN... | mitochondrial electron transport, ubiquinol to cytochrome c mRNA processing proton transmembrane transport RNA splicing mitochondrial inner membrane; mitochondrion electron transfer activity endonuclease activity nuclease activity Saccharomyces cerevisiae Membrane Mitochondrion Mitochondrion inner membrane mRNA proces... |
electron transport coupled proton transport intron homing mitochondrial electron transport, cytochrome c to oxygen mRNA processing RNA splicing | mitochondrial respiratory chain complex IV; mitochondrion | cytochrome-c oxidase activity endonuclease activity heme binding | Saccharomyces cerevisiae | Endonuclease Hydrolase Intron homing Membrane Mitochondrion mRNA processing mRNA splicing Nuclease Reference proteome Transmembrane Transmembrane helix | MVQRWLYSTN | MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVVGHAVLMIFFLVMPALIGGFGNQKRYESNNNNNQVMENKEYNLKLNYDKLGPYLAGLIEGDGTITVQNSSSMKKSKYRPLIVVVFKLEDLELANYLCNLTKCGKVYKKINRNYVLWTIHDLKGVYTLLNIINGYMRTPKYEAFVRGAEFMNNYINSTTITHNKLKNMDNIKIKPLDTSDIGSNAWLAGMTDADGNFSINLMNGKNRSSRAMPYYCLELRQNYQKNSNNNNINFSYFYIMSAIATYFNVNLYSRERNLNLLV... | electron transport coupled proton transport intron homing mitochondrial electron transport, cytochrome c to oxygen mRNA processing RNA splicing mitochondrial respiratory chain complex IV; mitochondrion cytochrome-c oxidase activity endonuclease activity heme binding Saccharomyces cerevisiae Endonuclease Hydrolase Intr... |
electron transport coupled proton transport intron homing mitochondrial electron transport, cytochrome c to oxygen mRNA processing RNA splicing | mitochondrial respiratory chain complex IV; mitochondrion | cytochrome-c oxidase activity endonuclease activity heme binding | Saccharomyces cerevisiae | Endonuclease Hydrolase Intron homing Mitochondrion mRNA processing mRNA splicing Nuclease Reference proteome | MVQRWLYSTN | MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVVGHAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVESGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMHKLPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFWFFGQTVATIIMLMMYNDMHFSKCWKLLKKWITNIMSTLFKALFVKMFMSYNNQQDKMMNNTMLKKDNIKRSSETTRKMLNNSM... | electron transport coupled proton transport intron homing mitochondrial electron transport, cytochrome c to oxygen mRNA processing RNA splicing mitochondrial respiratory chain complex IV; mitochondrion cytochrome-c oxidase activity endonuclease activity heme binding Saccharomyces cerevisiae Endonuclease Hydrolase Intr... |
Group I intron splicing mitochondrial electron transport, ubiquinol to cytochrome c mitochondrial mRNA processing mRNA processing proton transmembrane transport | mitochondrion | endonuclease activity RNA binding | Saccharomyces cerevisiae | Hydrolase Mitochondrion mRNA processing mRNA splicing Reference proteome | MAFRKSNVYL | MAFRKSNVYLSLVNSYIIDSPQPSSINYWWNMGSLLGLCLVIQIVTGIFMAMHYSSNIELAFSSVEHIMRDVHNGYILRYLHANGASFFFMVMFMHMAKGLYYGSYRSPRVTLWNVGVIIFILTIATAFLGYCCVYGQMSHWGATVITNLFSAIPFVGNDIVSWLWGGFSVSNPTIQRFFALHYLVPFIIAAMVIMHLMALHIHGSSNPLGITGNLDRIPMHSYFIFKDLVTVFLFMLILALFVFYSPNTLGQNMALLLITYVINILCAVCWKSLFIKYQWKIYNKTTYYFIIQNILNTKQLNNFVLKFNWTKQYNKMNI... | Group I intron splicing mitochondrial electron transport, ubiquinol to cytochrome c mitochondrial mRNA processing mRNA processing proton transmembrane transport mitochondrion endonuclease activity RNA binding Saccharomyces cerevisiae Hydrolase Mitochondrion mRNA processing mRNA splicing Reference proteome MAFRKSNVYL M... |
proton motive force-driven ATP synthesis proton motive force-driven mitochondrial ATP synthesis | mitochondrial inner membrane; mitochondrial proton-transporting ATP synthase complex; mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) | proton transmembrane transporter activity | Homo sapiens | 3D-structure Acetylation ATP synthesis Cardiomyopathy CF(0) Disease variant Hydrogen ion transport Ion transport Membrane Mitochondrion Primary mitochondrial disease Reference proteome Transmembrane Transmembrane helix Transport | MPQLNTTVWP | MPQLNTTVWPTMITPMLLTLFLITQLKMLNTNYHLPPSPKPMKMKNYNKPWEPKWTKICSLHSLPPQS | proton motive force-driven ATP synthesis proton motive force-driven mitochondrial ATP synthesis mitochondrial inner membrane; mitochondrial proton-transporting ATP synthase complex; mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) proton transmembrane transporter activity Homo sapiens 3D-str... |
electron transport coupled proton transport mitochondrial electron transport, cytochrome c to oxygen | mitochondrial respiratory chain complex IV | cytochrome-c oxidase activity heme binding metal ion binding | Neurospora crassa | Calcium Copper Direct protein sequencing Electron transport Heme Iron Lipoprotein Magnesium Membrane Metal-binding Mitochondrion Mitochondrion inner membrane Myristate Reference proteome Respiratory chain Translocase Transmembrane Transmembrane helix Transport | MSSISIWTER | MSSISIWTERWFLSTNAKDIGVLYLIFALFSGLLGTAFSVLIRMELSGPGVQYIADNQLYNAIITAHAILMIFFMVMPALIGGFGNFLLPLLVGGPDMAFPRLNNISFWLLPPSLLLLVFSACIEGGAGTGWTIYPPLSGVQSHSGPSVDLAIFALHLSGVSSLLGSINFITTIVNMRTPGIRLHKLALFGWAVVITAVLLLLSLPVLAGAITMLLTDRNFNTSFFETAGGGDPILFQHLFWFFGHPEVYILIIPGFGIISTTISAYSNKSVFGYIGMVYAMMSIGILGFIVWSHHMYTVGLDVDTRAYFTAATLIIAVP... | electron transport coupled proton transport mitochondrial electron transport, cytochrome c to oxygen mitochondrial respiratory chain complex IV cytochrome-c oxidase activity heme binding metal ion binding Neurospora crassa Calcium Copper Direct protein sequencing Electron transport Heme Iron Lipoprotein Magnesium Membr... |
actin filament polymerization activation of phospholipase A2 activity activation of phospholipase C activity activation of protein kinase B activity angiogenesis antibacterial humoral response antimicrobial humoral immune response mediated by antimicrobial peptide cell communication cell migration defense response to G... | actin cytoskeleton; angiogenin-PRI complex; basement membrane; chromosome; cytoplasmic vesicle; cytosol; extracellular region; extracellular space; growth cone; neuronal cell body; nucleolus; nucleus | actin binding copper ion binding DNA binding endonuclease activity heparin binding peptide binding protein homodimerization activity RNA endonuclease activity RNA nuclease activity rRNA binding signaling receptor binding | Homo sapiens | 3D-structure Amyotrophic lateral sclerosis Angiogenesis Cytoplasmic vesicle Developmental protein Differentiation Direct protein sequencing Disease variant Disulfide bond DNA-binding Endonuclease Hydrolase Neurodegeneration Nuclease Nucleus Protein synthesis inhibitor Pyrrolidone carboxylic acid Reference proteome Secr... | MVMGLGVLLL | MVMGLGVLLLVFVLGLGLTPPTLAQDNSRYTHFLTQHYDAKPQGRDDRYCESIMRRRGLTSPCKDINTFIHGNKRSIKAICENKNGNPHRENLRISKSSFQVTTCKLHGGSPWPPCQYRATAGFRNVVVACENGLPVHLDQSIFRRP | actin filament polymerization activation of phospholipase A2 activity activation of phospholipase C activity activation of protein kinase B activity angiogenesis antibacterial humoral response antimicrobial humoral immune response mediated by antimicrobial peptide cell communication cell migration defense response to G... |
blood coagulation plasminogen activation positive regulation of fibrinolysis | extracellular exosome; extracellular region; extracellular space; membrane; plasma membrane | heparin binding identical protein binding serine-type aminopeptidase activity serine-type endopeptidase activity | Homo sapiens | 3D-structure Alternative splicing Blood coagulation Direct protein sequencing Disease variant Disulfide bond Glycoprotein Hemostasis Heparin-binding Hydrolase Protease Reference proteome Repeat Secreted Serine protease Signal | MIFLYQVVHF | MIFLYQVVHFILFTSVSGECVTQLLKDTCFEGGDITTVFTPSAKYCQVVCTYHPRCLLFTFTAESPSEDPTRWFTCVLKDSVTETLPRVNRTAAISGYSFKQCSHQISACNKDIYVDLDMKGINYNSSVAKSAQECQERCTDDVHCHFFTYATRQFPSLEHRNICLLKHTQTGTPTRITKLDKVVSGFSLKSCALSNLACIRDIFPNTVFADSNIDSVMAPDAFVCGRICTHHPGCLFFTFFSQEWPKESQRNLCLLKTSESGLPSTRIKKSKALSGFSLQSCRHSIPVFCHSSFYHDTDFLGEELDIVAAKSHEACQKL... | blood coagulation plasminogen activation positive regulation of fibrinolysis extracellular exosome; extracellular region; extracellular space; membrane; plasma membrane heparin binding identical protein binding serine-type aminopeptidase activity serine-type endopeptidase activity Homo sapiens 3D-structure Alternative ... |
blood coagulation Factor XII activation fibrinolysis plasminogen activation positive regulation of fibrinolysis proteolysis zymogen activation | extracellular exosome; extracellular region; extracellular space; plasma membrane | serine-type endopeptidase activity | Homo sapiens | 3D-structure Blood coagulation Direct protein sequencing Disease variant Disulfide bond Fibrinolysis Glycoprotein Hemostasis Hydrolase Inflammatory response Protease Reference proteome Repeat Secreted Serine protease Signal Zymogen | MILFKQATYF | MILFKQATYFISLFATVSCGCLTQLYENAFFRGGDVASMYTPNAQYCQMRCTFHPRCLLFSFLPASSINDMEKRFGCFLKDSVTGTLPKVHRTGAVSGHSLKQCGHQISACHRDIYKGVDMRGVNFNVSKVSSVEECQKRCTSNIRCQFFSYATQTFHKAEYRNNCLLKYSPGGTPTAIKVLSNVESGFSLKPCALSEIGCHMNIFQHLAFSDVDVARVLTPDAFVCRTICTYHPNCLFFTFYTNVWKIESQRNVCLLKTSESGTPSSSTPQENTISGYSLLTCKRTLPEPCHSKIYPGVDFGGEELNVTFVKGVNVCQE... | blood coagulation Factor XII activation fibrinolysis plasminogen activation positive regulation of fibrinolysis proteolysis zymogen activation extracellular exosome; extracellular region; extracellular space; plasma membrane serine-type endopeptidase activity Homo sapiens 3D-structure Blood coagulation Direct protein s... |
complement activation, alternative pathway Notch signaling pathway proteolysis response to bacterium | extracellular space | endopeptidase activity serine-type endopeptidase activity | Mus musculus | 3D-structure Alternative splicing Complement alternate pathway Disulfide bond Glycoprotein Hydrolase Immunity Innate immunity Protease Reference proteome Secreted Serine protease Signal Zymogen | MHSSVYFVAL | MHSSVYFVALVILGAAVCAAQPRGRILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLLGAHSLSAPEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPLPLQYEDKEVEPGTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTYHDGVVTINMMCAESNRRDTCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIENITNGNMTS | complement activation, alternative pathway Notch signaling pathway proteolysis response to bacterium extracellular space endopeptidase activity serine-type endopeptidase activity Mus musculus 3D-structure Alternative splicing Complement alternate pathway Disulfide bond Glycoprotein Hydrolase Immunity Innate immunity Pr... |
digestion proteolysis | extracellular region | aspartic-type endopeptidase activity | Macaca fuscata fuscata | Aspartyl protease Digestion Direct protein sequencing Disulfide bond Hydrolase Phosphoprotein Protease Secreted Signal Zymogen | MKWLLLLGLV | MKWLLLLGLVALSECIIYKVPLVRKKSLRRNLSEHGLLKDFLKKHNLNPASKYFPQAEAPTLIDEQPLENYLDVEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYCSSLACTNHNLFNPQDSSTYQSTSGTLSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISSSGATPVFDNIWDQGLVSQDLFSVYLSADDQSGSVVIFGGIDSSYYTGSLNWVPVSVEGYWQISVDSITMNGEAIACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGASENSDGEMVVSCSAISSLPDI... | digestion proteolysis extracellular region aspartic-type endopeptidase activity Macaca fuscata fuscata Aspartyl protease Digestion Direct protein sequencing Disulfide bond Hydrolase Phosphoprotein Protease Secreted Signal Zymogen MKWLLLLGLV MKWLLLLGLVALSECIIYKVPLVRKKSLRRNLSEHGLLKDFLKKHNLNPASKYFPQAEAPTLIDEQPLENYLDVEYFGT... |
cellular response to UV-A collagen catabolic process extracellular matrix disassembly extracellular matrix organization positive regulation of protein-containing complex assembly protein metabolic process proteolysis | extracellular matrix; extracellular region; extracellular space | endopeptidase activity metalloendopeptidase activity peptidase activity serine-type endopeptidase activity zinc ion binding | Homo sapiens | 3D-structure Autocatalytic cleavage Calcium Collagen degradation Direct protein sequencing Disulfide bond Extracellular matrix Glycoprotein Host-virus interaction Hydrolase Metal-binding Metalloprotease Phosphoprotein Protease Reference proteome Repeat Secreted Signal Zinc Zymogen | MHSFPPLLLL | MHSFPPLLLLLFWGVVSHSFPATLETQEQDVDLVQKYLEKYYNLKNDGRQVEKRRNSGPVVEKLKQMQEFFGLKVTGKPDAETLKVMKQPRCGVPDVAQFVLTEGNPRWEQTHLTYRIENYTPDLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGNLAHAFQPGPGIGGDAHFDEDERWTNNFREYNLHRVAAHELGHSLGLSHSTDIGALMYPSYTFSGDVQLAQDDIDGIQAIYGRSQNPVQPIGPQTPKACDSKLTFDAITTIRGEVMFFKDRFYMRTNPFYPEVELNFISVF... | cellular response to UV-A collagen catabolic process extracellular matrix disassembly extracellular matrix organization positive regulation of protein-containing complex assembly protein metabolic process proteolysis extracellular matrix; extracellular region; extracellular space endopeptidase activity metalloendopepti... |
cellular response to amino acid stimulus cellular response to cell-matrix adhesion cellular response to interleukin-1 cellular response to reactive oxygen species cellular response to UV-A collagen catabolic process extracellular matrix organization female pregnancy innate immune response negative regulation of phospha... | cell body; cytosol; dendrite; extracellular matrix; extracellular space; mitochondrion; protein-containing complex | endopeptidase activity metalloendopeptidase activity metallopeptidase activity peptidase activity protein-containing complex binding zinc ion binding | Rattus norvegicus | Calcium Collagen degradation Direct protein sequencing Disulfide bond Extracellular matrix Glycoprotein Hydrolase Immunity Innate immunity Metal-binding Metalloprotease Protease Reference proteome Repeat Secreted Signal Zinc Zymogen | MKGLPVLLWL | MKGLPVLLWLCTAVCSSYPLHGSEEDAGMEVLQKYLENYYGLEKDVKQFTKKKDSSPVVKKIQEMQKFLGLKMTGKLDSNTMELMHKPRCGVPDVGGFSTFPGSPKWRKNHISYRIVNYTLDLPRESVDSAIERALKVWEEVTPLTFSRISEGEADIMISFAVEEHGDFIPFDGPGMVLAHAYAPGPGTNGDAHFDDDERWTDDVTGTNLFLVAAHELGHSLGLFHSANAEALMYPVYKSSTDLARFHLSQDDVDGIQSLYGPPTESPDVLVVPTKSNSLDPETLPMCSSALSFDAVSTLRGEVLFFKDRHFWRKSLRTP... | cellular response to amino acid stimulus cellular response to cell-matrix adhesion cellular response to interleukin-1 cellular response to reactive oxygen species cellular response to UV-A collagen catabolic process extracellular matrix organization female pregnancy innate immune response negative regulation of phospha... |
monoatomic cation transmembrane transport potassium ion transmembrane transport potassium ion transport | plasma membrane; potassium ion-transporting ATPase complex; potassium:proton antiporter complex | P-type potassium transmembrane transporter activity potassium ion binding | Escherichia coli | 3D-structure Cell inner membrane Cell membrane Ion transport Membrane Potassium Potassium transport Reference proteome Transmembrane Transmembrane helix Transport | MAAQGFLLIA | MAAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTTGVERVLFRALGVSDREMNWKQYLCAILGLNMLGLAVLFFMLLGQHYLPLNPQQLPGLSWDLALNTAVSFVTNTNWQSYSGETTLSYFSQMAGLTVQNFLSAASGIAVIFALIRAFTRQSMSTLGNAWVDLLRITLWVLVPVALLIALFFIQQGALQNFLPYQAVNTVEGAQQLLPMGPVASQEAIKMLGTNGGGFFNANSSHPFENPTALTNFVQMLAIFLIPTALCFAFGEVMGDRRQGRMLLWAMSVIFVICVGVVMWAEVQGNPHLLALGTDSSINM... | monoatomic cation transmembrane transport potassium ion transmembrane transport potassium ion transport plasma membrane; potassium ion-transporting ATPase complex; potassium:proton antiporter complex P-type potassium transmembrane transporter activity potassium ion binding Escherichia coli 3D-structure Cell inner membr... |
monoatomic cation transmembrane transport potassium ion transmembrane transport potassium ion transport | plasma membrane; potassium ion-transporting ATPase complex; potassium:proton antiporter complex | ATP binding ATP hydrolysis activity magnesium ion binding P-type potassium transmembrane transporter activity | Escherichia coli | 3D-structure ATP-binding Cell inner membrane Cell membrane Ion transport Magnesium Membrane Metal-binding Nucleotide-binding Phosphoprotein Potassium Potassium transport Reference proteome Translocase Transmembrane Transmembrane helix Transport | MSRKQLALFE | MSRKQLALFEPTLVVQALKEAVKKLNPQAQWRNPVMFIVWIGSLLTTCISIAMASGAMPGNALFSAAISGWLWITVLFANFAEALAEGRSKAQANSLKGVKKTAFARKLREPKYGAAADKVPADQLRKGDIVLVEAGDIIPCDGEVIEGGASVDESAITGESAPVIRESGGDFASVTGGTRILSDWLVIECSVNPGETFLDRMIAMVEGAQRRKTPNEIALTILLIALTIVFLLATATLWPFSAWGGNAVSVTVLVALLVCLIPTTIGGLLSAIGVAGMSRMLGANVIATSGRAVEAAGDVDVLLLDKTGTITLGNRQAS... | monoatomic cation transmembrane transport potassium ion transmembrane transport potassium ion transport plasma membrane; potassium ion-transporting ATPase complex; potassium:proton antiporter complex ATP binding ATP hydrolysis activity magnesium ion binding P-type potassium transmembrane transporter activity Escherichi... |
monoatomic cation transmembrane transport potassium ion transmembrane transport potassium ion transport | plasma membrane; potassium ion-transporting ATPase complex; potassium:proton antiporter complex | ATP binding P-type potassium transmembrane transporter activity | Escherichia coli | 3D-structure ATP-binding Cell inner membrane Cell membrane Ion transport Membrane Nucleotide-binding Potassium Potassium transport Reference proteome Transmembrane Transmembrane helix Transport | MSGLRPALST | MSGLRPALSTFIFLLLITGGVYPLLTTVLGQWWFPWQANGSLIREGDTVRGSALIGQNFTGNGYFHGRPSATAEMPYNPQASGGSNLAVSNPELDKLIAARVAALRAANPDASASVPVELVTASASGLDNNITPQAAAWQIPRVAKARNLSVEQLTQLIAKYSQQPLVKYIGQPVVNIVELNLALDKLDE | monoatomic cation transmembrane transport potassium ion transmembrane transport potassium ion transport plasma membrane; potassium ion-transporting ATPase complex; potassium:proton antiporter complex ATP binding P-type potassium transmembrane transporter activity Escherichia coli 3D-structure ATP-binding Cell inner mem... |
de novo' pyrimidine nucleobase biosynthetic process 'de novo' UMP biosynthetic process UMP biosynthetic process | cytosol | orotidine-5'-phosphate decarboxylase activity | Saccharomyces cerevisiae | 3D-structure Acetylation Decarboxylase Isopeptide bond Lyase Pyrimidine biosynthesis Reference proteome Ubl conjugation | MSKATYKERA | MSKATYKERAATHPSPVAAKLFNIMHEKQTNLCASLDVRTTKELLELVEALGPKICLLKTHVDILTDFSMEGTVKPLKALSAKYNFLLFEDRKFADIGNTVKLQYSAGVYRIAEWADITNAHGVVGPGIVSGLKQAAEEVTKEPRGLLMLAELSCKGSLATGEYTKGTVDIAKSDKDFVIGFIAQRDMGGRDEGYDWLIMTPGVGLDDKGDALGQQYRTVDDVVSTGSDIIIVGRGLFAKGRDAKVEGERYRKAGWEAYLRRCGQQN | de novo' pyrimidine nucleobase biosynthetic process 'de novo' UMP biosynthetic process UMP biosynthetic process cytosol orotidine-5'-phosphate decarboxylase activity Saccharomyces cerevisiae 3D-structure Acetylation Decarboxylase Isopeptide bond Lyase Pyrimidine biosynthesis Reference proteome Ubl conjugation MSKATYKE... |
astrocyte differentiation autosome genomic imprinting branching morphogenesis of an epithelial tube cartilage condensation cell population proliferation embryonic digit morphogenesis embryonic skeletal system morphogenesis epithelial cell proliferation lung development negative regulation of astrocyte differentiation n... | nucleolus; nucleoplasm; nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific kinase binding protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Mus musculus | DNA-binding Nucleus Phosphoprotein Proto-oncogene Reference proteome | MPSCTASTMP | MPSCTASTMPGMICKNPDLEFDSLQPCFYPDEDDFYFGGPDSTPPGEDIWKKFELLPTPPLSPSRAFPEHSPEPSNWATEMLLPEADLWGNPAEEDAFGLGGLGGLTPNPVILQDCMWSGFSAREKLERAVNEKLQHGHGPPGVSSACSAPGVGASSPGGRALGGSSSASHTGATLPTDLSHPAAECVDPAVVFPFPVNKRESASVPAAPTSAPATSAAVTSVSVPATAPVAAPARAGGRPASSGEAKALSTSGEDTLSDSDDEDDEEEDEEEEIDVVTVEKRRSSSNNKAVTTFTITVRPKTSALGLGRAQPGELILKR... | astrocyte differentiation autosome genomic imprinting branching morphogenesis of an epithelial tube cartilage condensation cell population proliferation embryonic digit morphogenesis embryonic skeletal system morphogenesis epithelial cell proliferation lung development negative regulation of astrocyte differentiation n... |
adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway chemotaxis ERK1 and ERK2 cascade mitotic cytokinesis phototaxis Ras protein signal transduction response to bacterium thermotaxis | cytosol; lipid droplet; plasma membrane | filamin binding G protein activity GDP binding GTP binding GTPase activity mitogen-activated protein kinase binding protein kinase B binding protein kinase inhibitor activity protein kinase regulator activity | Dictyostelium discoideum | Cell membrane GTP-binding Hydrolase Lipoprotein Membrane Methylation Nucleotide-binding Prenylation Reference proteome | MTEYKLVIVG | MTEYKLVIVGGGGVGKSALTIQLIQNHFIDEYDPTIEDSYRKQVSIDDETCLLDILDTAGQEEYSAMRDQYMRTGQGFLCVYSITSRSSYDEIASFREQILRVKDKDRVPLILVGNKADLDHERQVSVNEGQELAKGFNCPFMESSAKSRINVEEAFYSLVREIRKELKGDQSSGKAQKKKKQCLIL | adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway chemotaxis ERK1 and ERK2 cascade mitotic cytokinesis phototaxis Ras protein signal transduction response to bacterium thermotaxis cytosol; lipid droplet; plasma membrane filamin binding G protein activity GDP binding GTP binding GTPase activ... |
anti-Mullerian hormone signaling pathway cell-cell signaling gonadal mesoderm development Leydig cell differentiation Mullerian duct regression negative regulation of ovarian follicle development ovarian follicle development positive regulation of gene expression positive regulation of SMAD protein signal transduction ... | extracellular region; extracellular space | growth factor activity hormone activity signaling receptor binding type II transforming growth factor beta receptor binding | Homo sapiens | 3D-structure Differentiation Direct protein sequencing Disease variant Disulfide bond Glycoprotein Gonadal differentiation Growth factor Pseudohermaphroditism Reference proteome Secreted Signal | MRDLPLTSLA | MRDLPLTSLALVLSALGALLGTEALRAEEPAVGTSGLIFREDLDWPPGSPQEPLCLVALGGDSNGSSSPLRVVGALSAYEQAFLGAVQRARWGPRDLATFGVCNTGDRQAALPSLRRLGAWLRDPGGQRLVVLHLEEVTWEPTPSLRFQEPPPGGAGPPELALLVLYPGPGPEVTVTRAGLPGAQSLCPSRDTRYLVLAVDRPAGAWRGSGLALTLQPRGEDSRLSTARLQALLFGDDHRCFTRMTPALLLLPRSEPAPLPAHGQLDTVPFPPPRPSAELEESPPSADPFLETLTRLVRALRVPPARASAPRLALDPDAL... | anti-Mullerian hormone signaling pathway cell-cell signaling gonadal mesoderm development Leydig cell differentiation Mullerian duct regression negative regulation of ovarian follicle development ovarian follicle development positive regulation of gene expression positive regulation of SMAD protein signal transduction ... |
antibacterial humoral response immune response innate immune response modulation of process of another organism negative regulation of protein binding negative regulation of viral genome replication response to lipopolysaccharide | collagen-containing extracellular matrix; extracellular exosome; extracellular region; extracellular space; Golgi apparatus; specific granule lumen | DNA binding endopeptidase inhibitor activity enzyme binding mRNA binding serine-type endopeptidase inhibitor activity | Homo sapiens | 3D-structure Antibiotic Antimicrobial Direct protein sequencing Disulfide bond Immunity Innate immunity Protease inhibitor Reference proteome Repeat Secreted Serine protease inhibitor Signal | MKSSGLFPFL | MKSSGLFPFLVLLALGTLAPWAVEGSGKSFKAGVCPPKKSAQCLRYKKPECQSDWQCPGKKRCCPDTCGIKCLDPVDTPNPTRRKPGKCPVTYGQCLMLNPPNFCEMDGQCKRDLKCCMGMCGKSCVSPVKA | antibacterial humoral response immune response innate immune response modulation of process of another organism negative regulation of protein binding negative regulation of viral genome replication response to lipopolysaccharide collagen-containing extracellular matrix; extracellular exosome; extracellular region; ext... |
autophagosome maturation autophagy cellular response to arsenite ion cellular response to heat DNA damage response DNA repair double-strand break repair endoplasmic reticulum stress-induced pre-emptive quality control endosome to lysosome transport via multivesicular body sorting pathway ER-associated misfolded protein... | cytoplasm; cytoplasmic stress granule; cytosol; nucleus; site of double-strand break; VCP-NPL4-UFD1 AAA ATPase complex | ATP binding ATP hydrolysis activity lipid binding polyubiquitin modification-dependent protein binding | Sus scrofa | Acetylation ATP-binding Autophagy Cytoplasm Direct protein sequencing DNA damage DNA repair Endoplasmic reticulum Hydrolase Isopeptide bond Lipid-binding Methylation Nucleotide-binding Nucleus Phosphoprotein Reference proteome Transport Ubl conjugation Ubl conjugation pathway | MASGADSKGD | MASGADSKGDDLSTAILKQKNRPNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVHLGDVISIQPCPDVKYGKRIHVLPIDDTVEGITGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDTVIHCEGEPIKREDEEESLNEVGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEV... | autophagosome maturation autophagy cellular response to arsenite ion cellular response to heat DNA damage response DNA repair double-strand break repair endoplasmic reticulum stress-induced pre-emptive quality control endosome to lysosome transport via multivesicular body sorting pathway ER-associated misfolded protein... |
cell adhesion central nervous system development glial cell differentiation positive regulation of neuroblast proliferation skeletal system development | extracellular matrix; extracellular space; perineuronal net; synapse | hyaluronic acid binding structural molecule activity | Rattus norvegicus | Alternative splicing Direct protein sequencing Disulfide bond Extracellular matrix Glycoprotein Hyaluronic acid Immunoglobulin domain Reference proteome Repeat Secreted | MRSLLFLVLI | MRSLLFLVLISVCRADHLSDSYTPDQDRVIHIQAENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAFGSGIHKIRIKWTKLTSDYLREVDVFVSMGYHKKTYGGYQGRVFLKGGSDNDASLIITDLTLEDYGRYKCEVIEGLEDDTAVVALELQGVVFPYFPRLGRYNLNFHEARQACLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISR... | cell adhesion central nervous system development glial cell differentiation positive regulation of neuroblast proliferation skeletal system development extracellular matrix; extracellular space; perineuronal net; synapse hyaluronic acid binding structural molecule activity Rattus norvegicus Alternative splicing Direct ... |
astrocyte development Bergmann glial cell differentiation D-aspartate import across plasma membrane extracellular matrix organization gene expression intermediate filament organization intermediate filament-based process intracellular protein transport long-term synaptic potentiation negative regulation of neuron proje... | astrocyte end-foot; astrocyte projection; cell body; cell projection; cytoplasm; cytoplasmic side of lysosomal membrane; cytoskeleton; glial cell projection; intermediate filament; intermediate filament cytoskeleton; membrane; myelin sheath | identical protein binding integrin binding kinase binding structural constituent of cytoskeleton | Mus musculus | Alternative splicing Citrullination Coiled coil Cytoplasm Direct protein sequencing Intermediate filament Methylation Phosphoprotein Reference proteome | MERRRITSAR | MERRRITSARRSYASETVVRGLGPSRQLGTMPRFSLSRMTPPLPARVDFSLAGALNAGFKETRASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAELRELRLRLDQLTANSARLEVERDNFAQDLGTLRQKLQDETNLRLEAENNLAAYRQEADEATLARVDLERKVESLEEEIQFLRKIYEEEVRELREQLAQQQVHVEMDVAKPDLTAALREIRTQYEAVATSNMQETEEWYRSKFADLTDAASRNAELLRQAKHEANDYRRQLQALTCDLESLRGTNESLERQMREQEERHARESAS... | astrocyte development Bergmann glial cell differentiation D-aspartate import across plasma membrane extracellular matrix organization gene expression intermediate filament organization intermediate filament-based process intracellular protein transport long-term synaptic potentiation negative regulation of neuron proje... |
cellular response to light stimulus cellular response to UV-A G protein-coupled receptor signaling pathway phototransduction signal transduction visual perception | cone photoreceptor outer segment; cytosol; intercellular bridge; nucleoplasm; perinuclear region of cytoplasm; photoreceptor disc membrane; photoreceptor inner segment; photoreceptor outer segment; plasma membrane | G protein-coupled photoreceptor activity signaling receptor activity | Homo sapiens | Cell membrane Cell projection Chromophore Cytoplasm Disease variant Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Photoreceptor protein Receptor Reference proteome Retinal protein Sensory transduction Transducer Transmembrane Transmembrane helix Vision | MSEEEFYLFK | MSEEEFYLFKNISSVGPWDGPQYHIAPVWAFYLQAAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFSVFPVFVASCNGYFVFGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGNFRFSSKHALTVVLATWTIGIGVSIPPFFGWSRFIPEGLQCSCGPDWYTVGTKYRSESYTWFLFIFCFIVPLSLICFSYTQLLRALKAVAAQQQESATTQKAEREVSRMVVVMVGSFCVCYVPYAAFAMYMVNNRNHGLDLRLVTIPSFFSKSACIYNPIIYCFMNKQFQACIMKMVCGKAM... | cellular response to light stimulus cellular response to UV-A G protein-coupled receptor signaling pathway phototransduction signal transduction visual perception cone photoreceptor outer segment; cytosol; intercellular bridge; nucleoplasm; perinuclear region of cytoplasm; photoreceptor disc membrane; photoreceptor inn... |
cellular response to light stimulus G protein-coupled receptor signaling pathway phototransduction positive regulation of cytokinesis signal transduction visual perception | photoreceptor disc membrane; photoreceptor outer segment; plasma membrane | G protein-coupled photoreceptor activity photoreceptor activity | Homo sapiens | Chromophore Disease variant Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Photoreceptor protein Receptor Reference proteome Retinal protein Sensory transduction Transducer Transmembrane Transmembrane helix Vision | MAQQWSLQRL | MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISIVNQVSGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVRFDAKLAIVGIAFSWIWAAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYLQVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGYAFHPLMAALPAYFAKSATIYNPV... | cellular response to light stimulus G protein-coupled receptor signaling pathway phototransduction positive regulation of cytokinesis signal transduction visual perception photoreceptor disc membrane; photoreceptor outer segment; plasma membrane G protein-coupled photoreceptor activity photoreceptor activity Homo sapie... |
cellular response to light stimulus G protein-coupled receptor signaling pathway phototransduction positive regulation of cytokinesis visual perception | photoreceptor disc membrane; photoreceptor outer segment; plasma membrane | G protein-coupled photoreceptor activity identical protein binding photoreceptor activity | Homo sapiens | Cell membrane Chromophore Disease variant Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Photoreceptor protein Receptor Reference proteome Retinal protein Sensory transduction Transducer Transmembrane Transmembrane helix Vision | MAQQWSLQRL | MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISVVNQVYGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVRFDAKLAIVGIAFSWIWAAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAANPGYPFHPLMAALPAFFAKSATIYNPV... | cellular response to light stimulus G protein-coupled receptor signaling pathway phototransduction positive regulation of cytokinesis visual perception photoreceptor disc membrane; photoreceptor outer segment; plasma membrane G protein-coupled photoreceptor activity identical protein binding photoreceptor activity Homo... |
complement activation, classical pathway innate immune response negative regulation of complement activation, classical pathway positive regulation of protein catabolic process regulation of opsonization response to symbiotic bacterium T cell mediated immunity | blood microparticle; extracellular region; extracellular space; plasma membrane | RNA binding | Homo sapiens | 3D-structure Complement pathway Direct protein sequencing Disulfide bond Glycoprotein Immunity Innate immunity Reference proteome Repeat Secreted Signal Sushi | MHPPKTPSGA | MHPPKTPSGALHRKRKMAAWPFSRLWKVSDPILFQMTLIAALLPAVLGNCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNTFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTCEKITCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKED... | complement activation, classical pathway innate immune response negative regulation of complement activation, classical pathway positive regulation of protein catabolic process regulation of opsonization response to symbiotic bacterium T cell mediated immunity blood microparticle; extracellular region; extracellular sp... |
cell adhesion cell adhesion mediated by integrin cell migration cell-matrix adhesion endodermal cell differentiation extracellular matrix organization immune response liver regeneration negative regulation of blood coagulation negative regulation of endopeptidase activity negative regulation of fibrinolysis oligodendro... | alphav-beta3 integrin-vitronectin complex; basement membrane; blood microparticle; collagen-containing extracellular matrix; endoplasmic reticulum; extracellular exosome; extracellular region; extracellular space; Golgi lumen; intracellular membrane-bounded organelle; peptidase inhibitor complex; protein complex involv... | collagen binding extracellular matrix binding extracellular matrix structural constituent heparin binding identical protein binding integrin binding polysaccharide binding scavenger receptor activity | Homo sapiens | 3D-structure Cell adhesion Direct protein sequencing Disulfide bond Glycoprotein Heparin-binding Phosphoprotein Reference proteome Repeat Secreted Signal Sulfation | MAPLRPLLIL | MAPLRPLLILALLAWVALADQESCKGRCTEGFNVDKKCQCDELCSYYQSCCTDYTAECKPQVTRGDVFTMPEDEYTVYDDGEEKNNATVHEQVGGPSLTSDLQAQSKGNPEQTPVLKPEEEAPAPEVGASKPEGIDSRPETLHPGRPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEYQFQHQPSQEECEGSSLSAVFEHFAMMQRDSWEDIFELL... | cell adhesion cell adhesion mediated by integrin cell migration cell-matrix adhesion endodermal cell differentiation extracellular matrix organization immune response liver regeneration negative regulation of blood coagulation negative regulation of endopeptidase activity negative regulation of fibrinolysis oligodendro... |
viral entry into host cell viral penetration into host nucleus | host cell endoplasmic reticulum membrane; host cell nucleus; membrane; viral capsid | DNA binding structural molecule activity | B-lymphotropic polyomavirus | Alternative initiation Alternative splicing Capsid protein DNA-binding Host endoplasmic reticulum Host membrane Host nucleus Late protein Lipoprotein Membrane Myristate Transmembrane Transmembrane helix Viral penetration into host nucleus Virion Virus entry into host cell | MGGVLSLLFN | MGGVLSLLFNISEIAAELSLSTGFTVDAILTGEAFAAVSTEAAWLIEIEAVDLAGLSTLEALSLTGLTTEQFSLLSAIPTALNNAIGIGVFFQTVSGASAVVAAGVTTFGYSKEVPVVNMALVPWFPQVDYLFPGFTSFSYYLNAVLDWGESLFHAVGREVWRHLMRQATLQIGQATRAVAVRSTNELSHTLAQIAENARWALTSGPVHIYSSVQDYYRYLPARNPIQLRQEYRNRGEPPPSRADFEYQENREGQRARRELGYDEPRSGQYVEHYTAPGGAHQRVTQDWMLPLILGLYGDITPTWEVELNKLEKEEDGPS... | viral entry into host cell viral penetration into host nucleus host cell endoplasmic reticulum membrane; host cell nucleus; membrane; viral capsid DNA binding structural molecule activity B-lymphotropic polyomavirus Alternative initiation Alternative splicing Capsid protein DNA-binding Host endoplasmic reticulum Host m... |
bidirectional double-stranded viral DNA replication DNA duplex unwinding DNA replication protein hexamerization viral DNA genome replication | host cell nucleus | ATP binding ATP hydrolysis activity DNA binding DNA helicase activity TPR domain binding | Human papillomavirus 11 | ATP-binding DNA replication DNA-binding Early protein Helicase Host nucleus Hydrolase Isopeptide bond Nucleotide-binding Phosphoprotein Reference proteome Ubl conjugation | MADDSGTENE | MADDSGTENEGSGCTGWFMVEAIVEHTTGTQISEDEEEEVEDSGYDMVDFIDDRHITQNSVEAQALFNRQEADAHYATVQDLKRKYLGSPYVSPISNVANAVESEISPRLDAIKLTTQPKKVKRRLFETRELTDSGYGYSEVEAATQVEKHGDPENGGDGQERDTGRDIEGEGVEHREAEAVDDSTREHADTSGILELLKCKDIRSTLHGKFKDCFGLSFVDLIRPFKSDRTTCADWVVAGFGIHHSIADAFQKLIEPLSLYAHIQWLTNAWGMVLLVLIRFKVNKSRCTVARTLGTLLNIPENHMLIEPPKIQSGVRAL... | bidirectional double-stranded viral DNA replication DNA duplex unwinding DNA replication protein hexamerization viral DNA genome replication host cell nucleus ATP binding ATP hydrolysis activity DNA binding DNA helicase activity TPR domain binding Human papillomavirus 11ATP-binding DNA replication DNA-binding Early pro... |
viral budding from Golgi membrane viral budding via host ESCRT complex | host cell endoplasmic reticulum membrane; host cell Golgi apparatus; membrane; viral envelope; viral membrane; virion membrane | phospholipase D activity | Vaccinia virus ) | Host endoplasmic reticulum Host Golgi apparatus Host membrane Host-virus interaction Hydrolase Late protein Lipoprotein Membrane Palmitate Reference proteome Viral budding Viral budding via the host ESCRT complexes Viral envelope protein Viral release from host cell Virion | MWPFASVPAG | MWPFASVPAGAKCRLVETLPENMDFRSDHLTTFECFNEIITLAKKYIYIASFCCNPLSTTRGALIFDKLKEASEKGIKIIVLLDERGKRNLGELQSHCPDINFITVNIDKKNNVGLLLGCFWVSDDERCYVGNASFTGGSIHTIKTLGVYSDYPPLATDLRRRFDTFKAFNSAKNSWLNLCSAACCLPVSTAYHIKNPIGGVFFTDSPEHLLGYSRDLDTDVVIDKLKSAKTSIDIEHLAIVPTTRVDGNSYYWPDIYNSIIEAAINRGVKIRLLVGNWDKNDVYSMATARSLDALCVQNDLSVKVFTIQNNTKLLIVDD... | viral budding from Golgi membrane viral budding via host ESCRT complex host cell endoplasmic reticulum membrane; host cell Golgi apparatus; membrane; viral envelope; viral membrane; virion membrane phospholipase D activity Vaccinia virus )Host endoplasmic reticulum Host Golgi apparatus Host membrane Host-virus intera... |
viral budding via host ESCRT complex | viral nucleocapsid | nucleic acid binding structural constituent of virion zinc ion binding | Simian retrovirus SRV-1 | 3D-structure Capsid protein Cleavage on pair of basic residues Coiled coil Host-virus interaction Lipoprotein Metal-binding Myristate Phosphoprotein Repeat Ribosomal frameshifting Viral budding Viral budding via the host ESCRT complexes Viral matrix protein Viral nucleoprotein Viral release from host cell Virion Zinc Z... | MGQELSQHER | MGQELSQHERYVEQLKQALKTRGVKVKYADLLKFFDFVKDTCPWFPQEGTIDIKRWRRVGDCFQDYYNTFGPEKVPVTAFSYWNLIKELIDKKEVNPQVMAAVAQTEEILKTSSHTELTTKPSQNPDLDLISLDSDDEGAKGSSLKDKNLSCTKKPKRFPVLLTAQTSADPEDPNPSEVDWDGLEDEAAKYHNPDWPPFLTRPPPYNKATPSAPTVMAVVNPKEELKEKIAQLEEQIKLEELHQALISKLQKLKTGNETVTSPETAGGFSRTPHWPGQHIPKGKCCASREKEEQTPKDIFPVTETVDGQGQAWRHHNGFD... | viral budding via host ESCRT complex viral nucleocapsid nucleic acid binding structural constituent of virion zinc ion binding Simian retrovirus SRV-13D-structure Capsid protein Cleavage on pair of basic residues Coiled coil Host-virus interaction Lipoprotein Metal-binding Myristate Phosphoprotein Repeat Ribosomal fram... |
nucleotide metabolic process proteolysis viral process | viral nucleocapsid | aspartic-type endopeptidase activity DNA binding dUTP diphosphatase activity structural constituent of virion zinc ion binding | Simian retrovirus SRV-1 | Aspartyl protease Capsid protein Coiled coil DNA-binding Hydrolase Lipoprotein Magnesium Metal-binding Myristate Nucleotide metabolism Protease Repeat Ribosomal frameshifting Viral matrix protein Viral nucleoprotein Virion Zinc Zinc-finger | MGQELSQHER | MGQELSQHERYVEQLKQALKTRGVKVKYADLLKFFDFVKDTCPWFPQEGTIDIKRWRRVGDCFQDYYNTFGPEKVPVTAFSYWNLIKELIDKKEVNPQVMAAVAQTEEILKTSSHTELTTKPSQNPDLDLISLDSDDEGAKGSSLKDKNLSCTKKPKRFPVLLTAQTSADPEDPNPSEVDWDGLEDEAAKYHNPDWPPFLTRPPPYNKATPSAPTVMAVVNPKEELKEKIAQLEEQIKLEELHQALISKLQKLKTGNETVTSPETAGGFSRTPHWPGQHIPKGKCCASREKEEQTPKDIFPVTETVDGQGQAWRHHNGFD... | nucleotide metabolic process proteolysis viral process viral nucleocapsid aspartic-type endopeptidase activity DNA binding dUTP diphosphatase activity structural constituent of virion zinc ion binding Simian retrovirus SRV-1Aspartyl protease Capsid protein Coiled coil DNA-binding Hydrolase Lipoprotein Magnesium Metal-b... |
cholesterol biosynthetic process coenzyme A metabolic process isoprenoid biosynthetic process long-term synaptic potentiation negative regulation of amyloid-beta clearance negative regulation of protein catabolic process negative regulation of protein secretion regulation of ERK1 and ERK2 cascade sterol biosynthetic pr... | endoplasmic reticulum; endoplasmic reticulum membrane; peroxisomal membrane | coenzyme A binding GTPase regulator activity hydroxymethylglutaryl-CoA reductase (NADPH) activity NADPH binding | Homo sapiens | 3D-structure Alternative splicing Cholesterol biosynthesis Cholesterol metabolism Disease variant Endoplasmic reticulum Glycoprotein Isopeptide bond Limb-girdle muscular dystrophy Lipid biosynthesis Lipid metabolism Membrane NADP Oxidoreductase Peroxisome Phosphoprotein Reference proteome Steroid biosynthesis Steroid m... | MLSRLFRMHG | MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASTLAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTADTSKVSLGLDENVSKRIEPSVSLWQFYLSKMISMDI... | cholesterol biosynthetic process coenzyme A metabolic process isoprenoid biosynthetic process long-term synaptic potentiation negative regulation of amyloid-beta clearance negative regulation of protein catabolic process negative regulation of protein secretion regulation of ERK1 and ERK2 cascade sterol biosynthetic pr... |
amino acid biosynthetic process diaminopimelate biosynthetic process lysine biosynthetic process via diaminopimelate | cytosol | 4-hydroxy-tetrahydrodipicolinate reductase identical protein binding NAD binding NADP binding oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor | Escherichia coli | 3D-structure Amino-acid biosynthesis Cytoplasm Diaminopimelate biosynthesis Direct protein sequencing Lysine biosynthesis NAD NADP Oxidoreductase Reference proteome | MHDANIRVAI | MHDANIRVAIAGAGGRMGRQLIQAALALEGVQLGAALEREGSSLLGSDAGELAGAGKTGVTVQSSLDAVKDDFDVFIDFTRPEGTLNHLAFCRQHGKGMVIGTTGFDEAGKQAIRDAAADIAIVFAANFSVGVNVMLKLLEKAAKVMGDYTDIEIIEAHHRHKVDAPSGTALAMGEAIAHALDKDLKDCAVYSREGHTGERVPGTIGFATVRAGDIVGEHTAMFADIGERLEITHKASSRMTFANGAVRSALWLSGKESGLFDMRDVLDLNNL | amino acid biosynthetic process diaminopimelate biosynthetic process lysine biosynthetic process via diaminopimelate cytosol 4-hydroxy-tetrahydrodipicolinate reductase identical protein binding NAD binding NADP binding oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor Escherichia coli 3D-stru... |
mitochondrial cytochrome c oxidase assembly mitochondrial electron transport, cytochrome c to oxygen proton transmembrane transport | mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrial respiratory chain complex IV; mitochondrion | oxidoreductase activity zinc ion binding | Saccharomyces cerevisiae | 3D-structure Direct protein sequencing Membrane Metal-binding Mitochondrion Mitochondrion inner membrane Oxidoreductase Phosphoprotein Reference proteome Transit peptide Zinc | MLSLRQSIRF | MLSLRQSIRFFKPATRTLCSSRYLLQQKPVVKTAQNLAEVNGPETLIGPGAKEGTVPTDLDQETGLARLELLGKLEGIDVFDTKPLDSSRKGTMKDPIIIESYDDYRYVGCTGSPAGSHTIMWLKPTVNEVARCWECGSVYKLNPVGVPNDDHHH | mitochondrial cytochrome c oxidase assembly mitochondrial electron transport, cytochrome c to oxygen proton transmembrane transport mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrial respiratory chain complex IV; mitochondrion oxidoreductase activity zinc ion binding Saccharomyces cerevisiae... |
mitochondrial electron transport, cytochrome c to oxygen proton transmembrane transport | mitochondrial respiratory chain complex IV; mitochondrion | oxidoreductase activity | Saccharomyces cerevisiae | 3D-structure Cleavage on pair of basic residues Direct protein sequencing Membrane Mitochondrion Mitochondrion inner membrane Oxidoreductase Reference proteome Transit peptide Transmembrane Transmembrane helix | MLCQQMIRTT | MLCQQMIRTTAKRSSNIMTRPIIMKRSVHFKDGVYENIPFKVKGRKTPYALSHFGFFAIGFAVPFVACYVQLKKSGAF | mitochondrial electron transport, cytochrome c to oxygen proton transmembrane transport mitochondrial respiratory chain complex IV; mitochondrion oxidoreductase activity Saccharomyces cerevisiae 3D-structure Cleavage on pair of basic residues Direct protein sequencing Membrane Mitochondrion Mitochondrion inner membran... |
aerobic respiration cellular detoxification of hydrogen peroxide cellular response to growth factor stimulus cholesterol metabolic process hemoglobin metabolic process hydrogen peroxide catabolic process negative regulation of apoptotic process osteoblast differentiation positive regulation of cell division positive re... | catalase complex; cytoplasm; cytosol; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; focal adhesion; intracellular membrane-bounded organelle; membrane; mitochondrion; peroxisomal matrix; peroxisomal membrane; peroxisome; protein-containing complex; secretory granule lumen | aminoacylase activity antioxidant activity catalase activity enzyme binding heme binding identical protein binding metal ion binding NADP binding oxidoreductase activity, acting on peroxide as acceptor protein homodimerization activity | Homo sapiens | 3D-structure Acetylation Direct protein sequencing Heme Hydrogen peroxide Iron Metal-binding Mitogen NADP Oxidoreductase Peroxidase Peroxisome Phosphoprotein Reference proteome | MADSRDPASD | MADSRDPASDQMQHWKEQRAAQKADVLTTGAGNPVGDKLNVITVGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITKYSKAKVFEHIGKKTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDPILFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLSVEDAARLSQEDPDYGIRDLFNAIATGKYPSWTFYIQVMTFNQAETFPFNPFDLTKVWPHKDYPLIPVGKLVLNR... | aerobic respiration cellular detoxification of hydrogen peroxide cellular response to growth factor stimulus cholesterol metabolic process hemoglobin metabolic process hydrogen peroxide catabolic process negative regulation of apoptotic process osteoblast differentiation positive regulation of cell division positive re... |
chemotaxis | cytoplasm | phosphorelay response regulator activity protein-glutamate methylesterase activity protein-glutamine glutaminase activity | Salmonella typhimurium | 3D-structure Chemotaxis Cytoplasm Direct protein sequencing Hydrolase Phosphoprotein Reference proteome | MSKIRVLSVD | MSKIRVLSVDDSALMRQIMTEIINSHSDMEMVATAPDPLVARDLIKKFNPDVLTLDVEMPRMDGLDFLEKLMRLRPMPVVMVSSLTGKGSEVTLRALELGAIDFVTKPQLGIREGMLAYSEMIAEKVRTAARARIAAHKPMAAPTTLKAGPLLSSEKLIAIGASTGGTEAIRHVLQPLPLSSPAVIITQHMPPGFTRSFAERLNKLCQISVKEAEDGERVLPGHAYIAPGDKHMELARSGANYQIKIHDGPPVNRHRPSVDVLFHSVAKHAGRNAVGVILTGMGNDGAAGMLAMYQAGAWTIAQNEASCVVFGMPREAIN... | chemotaxis cytoplasm phosphorelay response regulator activity protein-glutamate methylesterase activity protein-glutamine glutaminase activity Salmonella typhimurium 3D-structure Chemotaxis Cytoplasm Direct protein sequencing Hydrolase Phosphoprotein Reference proteome MSKIRVLSVD MSKIRVLSVDDSALMRQIMTEIINSHSDMEMVATAPDPL... |
DNA metabolic process DNA modification double-strand break repair via nonhomologous end joining response to ATP | cytosol; euchromatin; nuclear matrix; nucleoplasm; nucleus | DNA binding DNA nucleotidylexotransferase activity DNA-directed DNA polymerase activity metal ion binding | Homo sapiens | 3D-structure Alternative splicing Magnesium Metal-binding Nucleotidyltransferase Nucleus Phosphoprotein Reference proteome Terminal addition Transferase | MDPPRASHLS | MDPPRASHLSPRKKRPRQTGALMASSPQDIKFQDLVVFILEKKMGTTRRAFLMELARRKGFRVENELSDSVTHIVAENNSGSDVLEWLQAQKVQVSSQPELLDVSWLIECIRAGKPVEMTGKHQLVVRRDYSDSTNPGPPKTPPIAVQKISQYACQRRTTLNNCNQIFTDAFDILAENCEFRENEDSCVTFMRAASVLKSLPFTIISMKDTEGIPCLGSKVKGIIEEIIEDGESSEVKAVLNDERYQSFKLFTSVFGVGLKTSEKWFRMGFRTLSKVRSDKSLKFTRMQKAGFLYYEDLVSCVTRAEAEAVSVLVKEAVW... | DNA metabolic process DNA modification double-strand break repair via nonhomologous end joining response to ATP cytosol; euchromatin; nuclear matrix; nucleoplasm; nucleus DNA binding DNA nucleotidylexotransferase activity DNA-directed DNA polymerase activity metal ion binding Homo sapiens 3D-structure Alternative splic... |
antimicrobial humoral immune response mediated by antimicrobial peptide arachidonic acid secretion cellular response to insulin stimulus fatty acid biosynthetic process innate immune response in mucosa lipid catabolic process phosphatidylcholine metabolic process phosphatidylglycerol metabolic process phospholipid meta... | cell surface; extracellular region; extracellular space; secretory granule | bile acid binding calcium ion binding calcium-dependent phospholipase A2 activity phospholipase A2 activity phospholipid binding signaling receptor binding | Rattus norvegicus | Autocatalytic cleavage Calcium Direct protein sequencing Disulfide bond Hydrolase Lipid metabolism Metal-binding Phospholipid metabolism Reference proteome Secreted Signal Zymogen | MKLLLLAALL | MKLLLLAALLTAGVTAHSISTRAVWQFRNMIKCTIPGSDPLREYNNYGCYCGLGGSGTPVDDLDRCCQTHDHCYNQAKKLESCKFLIDNPYTNTYSYKCSGNVITCSDKNNDCESFICNCDRQAAICFSKVPYNKEYKDLDTKKHC | antimicrobial humoral immune response mediated by antimicrobial peptide arachidonic acid secretion cellular response to insulin stimulus fatty acid biosynthetic process innate immune response in mucosa lipid catabolic process phosphatidylcholine metabolic process phosphatidylglycerol metabolic process phospholipid meta... |
acetylcholine catabolic process in synaptic cleft | plasma membrane; side of membrane; synapse; synaptic cleft | acetylcholinesterase activity | Tetronarce californica | 3D-structure Alternative splicing Cell membrane Direct protein sequencing Disulfide bond Glycoprotein GPI-anchor Hydrolase Lipoprotein Membrane Neurotransmitter degradation Serine esterase Signal Synapse | MNLLVTSSLG | MNLLVTSSLGVLLHLVVLCQADDHSELLVNTKSGKVMGTRVPVLSSHISAFLGIPFAEPPVGNMRFRRPEPKKPWSGVWNASTYPNNCQQYVDEQFPGFSGSEMWNPNREMSEDCLYLNIWVPSPRPKSTTVMVWIYGGGFYSGSSTLDVYNGKYLAYTEEVVLVSLSYRVGAFGFLALHGSQEAPGNVGLLDQRMALQWVHDNIQFFGGDPKTVTIFGESAGGASVGMHILSPGSRDLFRRAILQSGSPNCPWASVSVAEGRRRAVELGRNLNCNLNSDEELIHCLREKKPQELIDVEWNVLPFDSIFRFSFVPVIDGE... | acetylcholine catabolic process in synaptic cleft plasma membrane; side of membrane; synapse; synaptic cleft acetylcholinesterase activity Tetronarce californica 3D-structure Alternative splicing Cell membrane Direct protein sequencing Disulfide bond Glycoprotein GPI-anchor Hydrolase Lipoprotein Membrane Neurotransmit... |
fucose metabolic process glycolipid catabolic process glycosaminoglycan catabolic process glycoside catabolic process | azurophil granule lumen; cytoplasm; extracellular exosome; extracellular region; intracellular membrane-bounded organelle; lysosomal lumen; lysosome | alpha-L-fucosidase activity | Homo sapiens | 3D-structure Disease variant Glycoprotein Glycosidase Hydrolase Lipid metabolism Lysosome Phosphoprotein Reference proteome Signal | MRAPGMRSRP | MRAPGMRSRPAGPALLLLLLFLGAAESVRRAQPPRRYTPDWPSLDSRPLPAWFDEAKFGVFIHWGVFSVPAWGSEWFWWHWQGEGRPQYQRFMRDNYPPGFSYADFGPQFTARFFHPEEWADLFQAAGAKYVVLTTKHHEGFTNWPSPVSWNWNSKDVGPHRDLVGELGTALRKRNIRYGLYHSLLEWFHPLYLLDKKNGFKTQHFVSAKTMPELYDLVNSYKPDLIWSDGEWECPDTYWNSTNFLSWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCEDKFKPQSLPDHKWEMCTSIDKFSWGYRRDMALSDVTEESE... | fucose metabolic process glycolipid catabolic process glycosaminoglycan catabolic process glycoside catabolic process azurophil granule lumen; cytoplasm; extracellular exosome; extracellular region; intracellular membrane-bounded organelle; lysosomal lumen; lysosome alpha-L-fucosidase activity Homo sapiens 3D-structure... |
blood coagulation negative regulation of apoptotic process negative regulation of blood coagulation negative regulation of coagulation negative regulation of inflammatory response positive regulation of establishment of endothelial barrier proteolysis | endoplasmic reticulum; endoplasmic reticulum lumen; extracellular region; extracellular space; Golgi apparatus; Golgi lumen | calcium ion binding serine-type endopeptidase activity | Homo sapiens | 3D-structure Alternative splicing Blood coagulation Calcium Cleavage on pair of basic residues Direct protein sequencing Disease variant Disulfide bond EGF-like domain Endoplasmic reticulum Gamma-carboxyglutamic acid Glycoprotein Golgi apparatus Hemostasis Hydrolase Hydroxylation Phosphoprotein Protease Reference prote... | MWQLTSLLLF | MWQLTSLLLFVATWGISGTPAPLDSVFSSSERAHQVLRIRKRANSFLEELRHSSLERECIEEICDFEEAKEIFQNVDDTLAFWSKHVDGDQCLVLPLEHPCASLCCGHGTCIDGIGSFSCDCRSGWEGRFCQREVSFLNCSLDNGGCTHYCLEEVGWRRCSCAPGYKLGDDLLQCHPAVKFPCGRPWKRMEKKRSHLKRDTEDQEDQVDPRLIDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEYDLRRWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICL... | blood coagulation negative regulation of apoptotic process negative regulation of blood coagulation negative regulation of coagulation negative regulation of inflammatory response positive regulation of establishment of endothelial barrier proteolysis endoplasmic reticulum; endoplasmic reticulum lumen; extracellular re... |
regulation of sodium ion transport | axon; basolateral plasma membrane; melanosome; membrane; plasma membrane; sarcolemma | ATP binding ATP hydrolysis activity metal ion binding P-type sodium:potassium-exchanging transporter activity | Ovis aries | Acetylation ATP-binding Cell membrane Cell projection Direct protein sequencing Ion transport Magnesium Membrane Metal-binding Nucleotide-binding Phosphoprotein Potassium Potassium transport Reference proteome Sodium Sodium transport Sodium/potassium transport Translocase Transmembrane Transmembrane helix Transport | MGKGVGRDKY | MGKGVGRDKYEPAAVSEHGDKKKAKKERDMDELKKEVSMDDHKLSLDELHRKYGTDLNRGLTTARAAEILARDGPNALTPPPTTPEWVKFCRQLFGGFSMLLWIGAVLCFLAYGIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVI... | regulation of sodium ion transport axon; basolateral plasma membrane; melanosome; membrane; plasma membrane; sarcolemma ATP binding ATP hydrolysis activity metal ion binding P-type sodium:potassium-exchanging transporter activity Ovis aries Acetylation ATP-binding Cell membrane Cell projection Direct protein sequencing... |
actin filament organization ATP biosynthetic process binding of sperm to zona pellucida fructose 1,6-bisphosphate metabolic process fructose metabolic process glycolytic process muscle cell cellular homeostasis protein homotetramerization regulation of cell shape striated muscle contraction | actin cytoskeleton; cytosol; extracellular exosome; extracellular region; extracellular space; ficolin-1-rich granule lumen; I band; M band; membrane; nucleus; platelet alpha granule lumen; secretory granule lumen; sperm head; tertiary granule lumen | actin binding cadherin binding cytoskeletal protein binding fructose binding fructose-bisphosphate aldolase activity identical protein binding RNA binding tubulin binding | Homo sapiens | 3D-structure Acetylation Alternative splicing Cytoplasm Direct protein sequencing Disease variant Glycogen storage disease Glycolysis Hereditary hemolytic anemia Hydroxylation Isopeptide bond Lyase Phosphoprotein Reference proteome Schiff base Ubl conjugation | MPYQYPALTP | MPYQYPALTPEQKKELSDIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYRQLLLTADDRVNPCIGGVILFHETLYQKADDGRPFPQVIKSKGGVVGIKVDKGVVPLAGTNGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPSALAIMENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHIYLEGTLLKPNMVTPGHACTQKFSHEEIAMATVTALRRTVPPAVTGITFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKEN... | actin filament organization ATP biosynthetic process binding of sperm to zona pellucida fructose 1,6-bisphosphate metabolic process fructose metabolic process glycolytic process muscle cell cellular homeostasis protein homotetramerization regulation of cell shape striated muscle contraction actin cytoskeleton; cytosol;... |
glutamine metabolic process GMP biosynthetic process | cytosol | ATP binding GMP synthase (glutamine-hydrolyzing) activity GMP synthase activity identical protein binding | Escherichia coli | 3D-structure ATP-binding Direct protein sequencing Glutamine amidotransferase GMP biosynthesis Ligase Nucleotide-binding Purine biosynthesis Reference proteome | MTENIHKHRI | MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGVPVFGVCYGMQTMAMQLGGHVEASNEREFGYAQVEVVNDSALVRGIEDALTADGKPLLDVWMSHGDKVTAIPSDFITVASTESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAVARIREQVGDDKVILGLSGGVDSSVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVLDMFGDHFGLNIVHVPAEDRFLSALAGENDPEAKRKIIGRVFVEVFD... | glutamine metabolic process GMP biosynthetic process cytosol ATP binding GMP synthase (glutamine-hydrolyzing) activity GMP synthase activity identical protein binding Escherichia coli 3D-structure ATP-binding Direct protein sequencing Glutamine amidotransferase GMP biosynthesis Ligase Nucleotide-binding Purine biosynth... |
adult locomotory behavior negative regulation of peptidase activity negative regulation of proteolysis | collagen-containing extracellular matrix; cytoplasm; cytosol; extracellular exosome; extracellular region; extracellular space; ficolin-1-rich granule lumen; nucleolus; nucleus; secretory granule lumen; tertiary granule lumen | cysteine-type endopeptidase inhibitor activity endopeptidase inhibitor activity protease binding RNA binding | Homo sapiens | 3D-structure Acetylation Cytoplasm Direct protein sequencing Disease variant Epilepsy Neurodegeneration Nucleus Protease inhibitor Reference proteome Thiol protease inhibitor | MMCGAPSATQ | MMCGAPSATQPATAETQHIADQVRSQLEEKENKKFPVFKAVSFKSQVVAGTNYFIKVHVGDEDFVHLRVFQSLPHENKPLTLSNYQTNKAKHDELTYF | adult locomotory behavior negative regulation of peptidase activity negative regulation of proteolysis collagen-containing extracellular matrix; cytoplasm; cytosol; extracellular exosome; extracellular region; extracellular space; ficolin-1-rich granule lumen; nucleolus; nucleus; secretory granule lumen; tertiary granu... |
arachidonic acid secretion lipid catabolic process phospholipid metabolic process | extracellular region | calcium ion binding phospholipase A2 activity toxin activity | Vipera ammodytes meridionalis | 3D-structure Direct protein sequencing Disulfide bond Neurotoxin Postsynaptic neurotoxin Secreted Toxin | NLFQFGDMIL | NLFQFGDMILQKTGKEAVHSYAIYGCYCGWGGQGRAQDATDRCCFAQDCCYGRVNDCNPKTATYTYSFENGDIVCGDNDLCLRAVCECDRAAAICLGENVNTYDKNYEYYSISHCTEESEQC | arachidonic acid secretion lipid catabolic process phospholipid metabolic process extracellular region calcium ion binding phospholipase A2 activity toxin activity Vipera ammodytes meridionalis 3D-structure Direct protein sequencing Disulfide bond Neurotoxin Postsynaptic neurotoxin Secreted Toxin NLFQFGDMIL NLFQFGDMILQ... |
activin receptor signaling pathway cellular response to insulin stimulus cellular response to starvation fat cell differentiation negative regulation of follicle-stimulating hormone secretion negative regulation of hepatocyte growth factor production negative regulation of insulin secretion positive regulation of folli... | extracellular space; perinuclear region of cytoplasm | cytokine activity growth factor activity hormone activity protein homodimerization activity | Sus scrofa | Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Glycoprotein Growth factor Hormone Reference proteome Secreted Signal | MDGLPGRALG | MDGLPGRALGAACLLLLAAGWLGPEAWGSPTPPPSPAAPPPPPPPGALGGSQDTCTSCGGFRRPEELGRLDGDFLEAVKRHILNRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGRVEIPHLDGHASPGADGQERVSEIISFAETDGLASSRVRLYFFISNEGNQNLFVVQASLWLYLKLLPYVLEKGSRRKVRVKVYFQEPGHGDRWDVVEKRVDLKRSGWHTLPLTEAIQALFERGERRLNLDVQCDGCQELAVVPVFVDPGEESHRPFVVVQARLVDSRHRIRKRGLECDGRTNLCCRQQFFIDFRLIGWSDW... | activin receptor signaling pathway cellular response to insulin stimulus cellular response to starvation fat cell differentiation negative regulation of follicle-stimulating hormone secretion negative regulation of hepatocyte growth factor production negative regulation of insulin secretion positive regulation of folli... |
female pregnancy positive regulation of angiogenesis positive regulation of gene expression regulation of catalytic activity | extracellular region | hormone activity | Homo sapiens | 3D-structure Alternative splicing Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Hormone Pyrrolidone carboxylic acid Reference proteome Secreted Signal | MPRLFFFHLL | MPRLFFFHLLGVCLLLNQFSRAVADSWMEEVIKLCGRELVRAQIAICGMSTWSKRSLSQEDAPQTPRPVAEIVPSFINKDTETINMMSEFVANLPQELKLTLSEMQPALPQLQQHVPVLKDSSLLFEEFKKLIRNRQSEAADSSPSELKYLGLDTHSRKKRQLYSALANKCCHVGCTKRSLARFC | female pregnancy positive regulation of angiogenesis positive regulation of gene expression regulation of catalytic activity extracellular region hormone activity Homo sapiens 3D-structure Alternative splicing Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Hormone Pyrrolidone carboxylic aci... |
aggressive behavior behavioral fear response cellular response to cAMP cellular response to oxidative stress cellular response to transforming growth factor beta stimulus cellular response to virus cellular response to vitamin D chemical synaptic transmission G protein-coupled opioid receptor signaling pathway general ... | axon; axon terminus; cell body fiber; chromaffin granule lumen; dendrite; extracellular region; neuronal cell body; neuronal dense core vesicle lumen; perikaryon; plasma membrane; symmetric synapse; synaptic vesicle lumen | opioid peptide activity opioid receptor binding receptor ligand activity | Rattus norvegicus | Cleavage on pair of basic residues Cytoplasmic vesicle Direct protein sequencing Disulfide bond Endorphin Neuropeptide Opioid peptide Phosphoprotein Reference proteome Secreted Signal | MAQFLRLCIW | MAQFLRLCIWLLALGSCLLATVQADCSQDCAKCSYRLVRPGDINFLACTLECEGQLPSFKIWETCKDLLQVSKPEFPWDNIDMYKDSSKQDESHLLAKKYGGFMKRYGGFMKKMDELYPVEPEEEANGGEILAKRYGGFMKKDADEGDTLANSSDLLKELLGTGDNRAKDSHQQESTNNDEDSTSKRYGGFMRGLKRSPQLEDEAKELQKRYGGFMRRVGRPEWWMDYQKRYGGFLKRFAESLPSDEEGESYSKEVPEMEKRYGGFMRF | aggressive behavior behavioral fear response cellular response to cAMP cellular response to oxidative stress cellular response to transforming growth factor beta stimulus cellular response to virus cellular response to vitamin D chemical synaptic transmission G protein-coupled opioid receptor signaling pathway general ... |
blood vessel endothelial cell migration cell projection organization female pregnancy mammary gland development myoblast differentiation negative regulation of myoblast differentiation neuroblast proliferation positive regulation of angiogenesis positive regulation of blood vessel endothelial cell migration positive re... | endoplasmic reticulum; extracellular space | growth factor activity hormone activity prolactin receptor binding | Mus musculus | Alternative splicing Disulfide bond Endoplasmic reticulum Glycoprotein Hormone Reference proteome Secreted Signal | MLPSLIQPCS | MLPSLIQPCSWILLLLLVNSSLLWKNVASFPMCAMRNGRCFMSFEDTFELAGSLSHNISIEVSELFTEFEKHYSNVSGLRDKSPMRCNTSFLPTPENKEQARLTHYSALLKSGAMILDAWESPLDDLVSELSTIKNVPDIIISKATDIKKKINAVRNGVNALMSTMLQNGDEEKKNPAWFLQSDNEDARIHSLYGMISCLDNDFKKVDIYLNVLKCYMLKIDNC | blood vessel endothelial cell migration cell projection organization female pregnancy mammary gland development myoblast differentiation negative regulation of myoblast differentiation neuroblast proliferation positive regulation of angiogenesis positive regulation of blood vessel endothelial cell migration positive re... |
complement activation, lectin pathway establishment of skin barrier intermediate filament organization keratinization negative regulation of inflammatory response protein heterotetramerization | collagen-containing extracellular matrix; cornified envelope; cytoplasm; keratin filament; membrane | carbohydrate binding protein heterodimerization activity structural constituent of skin epidermis | Mus musculus | Cell membrane Citrullination Coiled coil Cytoplasm Direct protein sequencing Disease variant Intermediate filament Keratin Membrane Methylation Phosphoprotein Reference proteome | MSLQCSSRSL | MSLQCSSRSLCRGGGGSRNFSSGSAGLVSFQRRSTSSSMRRSGGGGGGRFSGGGFCGSSGSGFGSKSLMNLGGGRSISKSVAGGGGSFCGGFGGGSYGGGGFGGGSYGGGGFGGGSFGGGGFGGSGFGGGLGGGGGFGSGGGFGGGRFGSMGPVCPPGGIQEVTINQSLLQPLNVEVDPQIQKVKSQEREQIKSLNDKFASFIDKVRFLEQQNQVLQTKWELLQQVDTTTRTQNLDPFFENYISILRRKVDSLKSDQSRMDSELKNMQDLVEEYRTKYEDEINKRTNAENEFVTIKKDVDSAYMTKVELQAKADALQQDI... | complement activation, lectin pathway establishment of skin barrier intermediate filament organization keratinization negative regulation of inflammatory response protein heterotetramerization collagen-containing extracellular matrix; cornified envelope; cytoplasm; keratin filament; membrane carbohydrate binding protei... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.