Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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microtubule-based process | cytoplasm; microtubule; nucleus; spindle | GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton | Physarum polycephalum | Acetylation Cytoplasm Cytoskeleton GTP-binding Hydrolase Magnesium Metal-binding Microtubule Nucleotide-binding Nucleus | MREIISIHIG | MREIISIHIGQAGAQVGNACWELYCLEHGINPDGQMPSDKSVGGGDDAFNTFFSETSSGKHVPRAIYLDLEPTVIDEIRTGTYRQLFHPEQLITGKEDAANNYARGHYTVGKEIVDLCLDRVRKLADQCSGLQGFLVFHSVGGGTGSGFGSLLLERLSVDYGKKSKLDFCVYPSPQVSTAVVEPYNSVLSTHGLLEHTDVAFMLDNEAIYDLCKKSLDIDRPSYANLNRLVAQVISSLTTSLRFDGALNVDINEFQTNLVPYPRIHFMLASYAPVISAEKAFHEQLSVAELTNTVFEPSSMMAKCDPRHGKYMACCLMYR... | microtubule-based process cytoplasm; microtubule; nucleus; spindle GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton Physarum polycephalum Acetylation Cytoplasm Cytoskeleton GTP-binding Hydrolase Magnesium Metal-binding Microtubule Nucleotide-binding Nucleus MREIISIHIG MREIISIHIGQA... |
platelet activation protein polymerization | fibrinogen complex | metal ion binding signaling receptor binding | Petromyzon marinus | 3D-structure Blood coagulation Calcium Coiled coil Disulfide bond Glycoprotein Hemostasis Metal-binding Secreted Signal | MGRIGTPVFL | MGRIGTPVFLAFLSALTCSLQVHAQVRDLKQCSNDPEFGRYCPTTCGVADVLSKYAKGVDEDSSFIDSVLTQLAAKHGIVEGNVNIVNEDVRITRDEAQIIKDSGQKTVQKILEEVRILEQIGVSHDAQIQELSEMWRVNQQFVTRLQQQLVDIRQTCSRSCQDTTANKISPITGKDCQQVVDNGGKDSGLYYIKPLKAKQPFLVFCEIENGNGWTVIQHRHDGSVNFTRDWVSYREGFGYLAPTLTTEFWLGNEKIHLLTGQQAYRLRIDLTDWENTHRYADYGHFKLTPESDEYRLFYSMYLDGDAGNAFDGFDFGDD... | platelet activation protein polymerization fibrinogen complex metal ion binding signaling receptor binding Petromyzon marinus 3D-structure Blood coagulation Calcium Coiled coil Disulfide bond Glycoprotein Hemostasis Metal-binding Secreted Signal MGRIGTPVFL MGRIGTPVFLAFLSALTCSLQVHAQVRDLKQCSNDPEFGRYCPTTCGVADVLSKYAKGVDEDS... |
astrocyte development axon development axon ensheathment cell maturation central nervous system myelination inflammatory response long-chain fatty acid biosynthetic process myelination positive regulation of gene expression | myelin sheath; plasma membrane | structural constituent of myelin sheath | Bos taurus | Alternative splicing Cell membrane Direct protein sequencing Disulfide bond Lipoprotein Membrane Palmitate Phosphoprotein Reference proteome Transmembrane Transmembrane helix | MGLLECCARC | MGLLECCARCLVGAPFASLVATGLCFFGVALFCGCGHEALTGTEKLIETYFSKNYQDYEYLINVIHAFQYVIYGTASFFFLYGALLLAEGFYTTGAVRQIFGDYKTTICGKGLSATVTGGQKGRGSRGQHQAHSLERVCHCLGKWLGHPDKFVGITYALTVVWLLVFACSAVPVYIYFNTWTTCQSIAAPSKTSASIGTLCADARMYGVLPWNAFPGKVCGSNLLSICKTAEFQMTFHLFIAAFVGAAATLVSLLTFMIAATYNFAVLKLMGRGTKF | astrocyte development axon development axon ensheathment cell maturation central nervous system myelination inflammatory response long-chain fatty acid biosynthetic process myelination positive regulation of gene expression myelin sheath; plasma membrane structural constituent of myelin sheath Bos taurus Alternative sp... |
brown fat cell differentiation cellular response to lithium ion cellular response to tumor necrosis factor cholesterol homeostasis fatty acid metabolic process fatty acid transport long-chain fatty acid transport negative regulation of DNA-templated transcription positive regulation of cell population proliferation pos... | cytoplasm; cytosol; nucleoplasm; nucleus | fatty acid binding hormone receptor binding long-chain fatty acid binding long-chain fatty acid transporter activity | Mus musculus | 3D-structure Acetylation Cytoplasm Direct protein sequencing Lipid-binding Nucleus Phosphoprotein Reference proteome Transport | MCDAFVGTWK | MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDLVTIRSESTFKNTEISFKLGVEFDEITADDRKVKSIITLDGGALVQVQKWDGKSTTIKRKRDGDKLVVECVMKGVTSTRVYERA | brown fat cell differentiation cellular response to lithium ion cellular response to tumor necrosis factor cholesterol homeostasis fatty acid metabolic process fatty acid transport long-chain fatty acid transport negative regulation of DNA-templated transcription positive regulation of cell population proliferation pos... |
digestion lipid catabolic process lipid metabolic process response to bacterium response to food | extracellular region | enzyme activator activity lipase binding | Homo sapiens | Diabetes mellitus Digestion Direct protein sequencing Disulfide bond Lipid degradation Lipid metabolism Reference proteome Secreted Signal | MEKILILLLV | MEKILILLLVALSVAYAAPGPRGIIINLENGELCMNSAQCKSNCCQHSSALGLARCTSMASENSECSVKTLYGIYYKCPCERGLTCEGDKTIVGSITNTNFGICHDAGRSKQ | digestion lipid catabolic process lipid metabolic process response to bacterium response to food extracellular region enzyme activator activity lipase binding Homo sapiens Diabetes mellitus Digestion Direct protein sequencing Disulfide bond Lipid degradation Lipid metabolism Reference proteome Secreted Signal MEKILILLL... |
mRNA processing mRNA transport regulation of nuclear-transcribed mRNA poly(A) tail shortening regulation of translational initiation | cytoplasm; cytoplasmic stress granule; cytosol; intracellular non-membrane-bounded organelle; nucleus; ribonucleoprotein complex; ribosome | molecular condensate scaffold activity mRNA 3'-UTR binding mRNA binding poly(A) binding poly(U) RNA binding promoter-specific chromatin binding ribonuclease inhibitor activity | Saccharomyces cerevisiae | 3D-structure Acetylation Cytoplasm Direct protein sequencing Isopeptide bond Methylation mRNA processing mRNA transport Nucleus Phosphoprotein Reference proteome Repeat RNA-binding Translation regulation Transport Ubl conjugation | MADITDKTAE | MADITDKTAEQLENLNIQDDQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQ... | mRNA processing mRNA transport regulation of nuclear-transcribed mRNA poly(A) tail shortening regulation of translational initiation cytoplasm; cytoplasmic stress granule; cytosol; intracellular non-membrane-bounded organelle; nucleus; ribonucleoprotein complex; ribosome molecular condensate scaffold activity mRNA 3'-U... |
DNA damage response error-prone translesion synthesis SOS response translesion synthesis | DNA polymerase V complex; membrane; plasma membrane | ATP-dependent activity, acting on DNA damaged DNA binding DNA-directed DNA polymerase activity single-stranded DNA binding | Escherichia coli | DNA damage DNA repair Reference proteome SOS mutagenesis SOS response | MFALCDVNAF | MFALCDVNAFYASCETVFRPDLWGKPVVVLSNNDGCVIARNAEAKALGVKMGDPWFKQKDLFRRCGVVCFSSNYELYADMSNRVMSTLEELSPRVEIYSIDEAFCDLTGVRNCRDLTDFGREIRATVLQRTHLTVGVGIAQTKTLAKLANHAAKKWQRQTGGVVDLSNLERQRKLMSALPVDDVWGIGRRISKKLDAMGIKTVLDLADTDIRFIRKHFNVVLERTVRELRGEPCLQLEEFAPTKQEIICSRSFGERITDYPSMRQAICSYAARAAEKLRSEHQYCRFISTFIKTSPFALNEPYYGNSASVKLLTPTQDSR... | DNA damage response error-prone translesion synthesis SOS response translesion synthesis DNA polymerase V complex; membrane; plasma membrane ATP-dependent activity, acting on DNA damaged DNA binding DNA-directed DNA polymerase activity single-stranded DNA binding Escherichia coli DNA damage DNA repair Reference proteom... |
carbohydrate metabolic process cell differentiation cell population proliferation maintenance of gastrointestinal epithelium negative regulation of cell population proliferation response to immobilization stress response to iron ion response to peptide hormone | extracellular region; extracellular space | growth factor activity | Homo sapiens | 3D-structure Direct protein sequencing Disulfide bond Growth factor Reference proteome Secreted Signal | MATMENKVIC | MATMENKVICALVLVSMLALGTLAEAQTETCTVAPRERQNCGFPGVTPSQCANKGCCFDDTVRGVPWCFYPNTIDVPPEEECEF | carbohydrate metabolic process cell differentiation cell population proliferation maintenance of gastrointestinal epithelium negative regulation of cell population proliferation response to immobilization stress response to iron ion response to peptide hormone extracellular region; extracellular space growth factor act... |
nitric oxide biosynthetic process | intracellular membrane-bounded organelle; mitochondrial outer membrane; nitric-oxide synthase complex | enzyme activator activity heme binding metal ion binding nitrite reductase (NO-forming) activity ubiquinol-cytochrome-c reductase activity | Rattus norvegicus | 3D-structure Acetylation Direct protein sequencing Electron transport Heme Iron Membrane Metal-binding Mitochondrion Mitochondrion outer membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport | MATPEASGSG | MATPEASGSGRNGQGSDPAVTYYRLEEVAKRNTAEETWMVIHGRVYDITRFLSEHPGGEEVLLEQAGADATESFEDVGHSPDAREMLKQYYIGDVHPNDLKPKDGDKDPSKNNSCQSSWAYWIVPIVGAILIGFLYRHFWADSKSS | nitric oxide biosynthetic process intracellular membrane-bounded organelle; mitochondrial outer membrane; nitric-oxide synthase complex enzyme activator activity heme binding metal ion binding nitrite reductase (NO-forming) activity ubiquinol-cytochrome-c reductase activity Rattus norvegicus 3D-structure Acetylation Di... |
epoxygenase P450 pathway nicotine metabolic process response to calcium ion response to metal ion response to organic cyclic compound xenobiotic metabolic process | cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle | arachidonic acid epoxygenase activity aromatase activity heme binding iron ion binding oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen steroid hydroxylase a... | Rattus norvegicus | Alternative splicing Direct protein sequencing Endoplasmic reticulum Heme Iron Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Phosphoprotein Reference proteome | MEPSILLLLA | MEPSILLLLALLVGFLLLLVRGHPKSRGNFPPGPRPLPLLGNLLQLDRGGLLNSFMQLREKYGDVFTVHLGPRPVVMLCGTDTIKEALVGQAEDFSGRGTIAVIEPIFKEYGVIFANGERWKALRRFSLATMRDFGMGKRSVEERIQEEAQCLVEELRKSQGAPLDPTFLFQCITANIICSIVFGERFDYTDRQFLRLLELFYRTFSLLSSFSSQVFEFFSGFLKYFPGAHRQISKNLQEILDYIGHIVEKHRATLDPSAPRDFIDTYLLRMEKEKSNHHTEFHHENLMISLLSLFFAGTETGSTTLRYGFLLMLKYPHV... | epoxygenase P450 pathway nicotine metabolic process response to calcium ion response to metal ion response to organic cyclic compound xenobiotic metabolic process cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle arachidonic acid epoxygenase activity aromatase activity heme binding iro... |
cholesterol homeostasis cholesterol metabolic process cholesterol transport high-density lipoprotein particle remodeling lipid metabolic process lipoprotein biosynthetic process phosphatidylcholine biosynthetic process phosphatidylcholine metabolic process phospholipid metabolic process regulation of high-density lipop... | extracellular exosome; extracellular region; extracellular space; high-density lipoprotein particle | 1-alkyl-2-acetylglycerophosphocholine esterase activity apolipoprotein A-I binding phosphatidylcholine-sterol O-acyltransferase activity platelet-activating factor acetyltransferase activity sterol esterase activity | Homo sapiens | 3D-structure Acyltransferase Cholesterol metabolism Corneal dystrophy Direct protein sequencing Disease variant Disulfide bond Glycoprotein Hydrolase Lipid metabolism Reference proteome Secreted Signal Steroid metabolism Sterol metabolism Transferase | MGPPGSPWQW | MGPPGSPWQWVTLLLGLLLPPAAPFWLLNVLFPPHTTPKAELSNHTRPVILVPGCLGNQLEAKLDKPDVVNWMCYRKTEDFFTIWLDLNMFLPLGVDCWIDNTRVVYNRSSGLVSNAPGVQIRVPGFGKTYSVEYLDSSKLAGYLHTLVQNLVNNGYVRDETVRAAPYDWRLEPGQQEEYYRKLAGLVEEMHAAYGKPVFLIGHSLGCLHLLYFLLRQPQAWKDRFIDGFISLGAPWGGSIKPMLVLASGDNQGIPIMSSIKLKEEQRITTTSPWMFPSRMAWPEDHVFISTPSFNYTGRDFQRFFADLHFEEGWYMWLQ... | cholesterol homeostasis cholesterol metabolic process cholesterol transport high-density lipoprotein particle remodeling lipid metabolic process lipoprotein biosynthetic process phosphatidylcholine biosynthetic process phosphatidylcholine metabolic process phospholipid metabolic process regulation of high-density lipop... |
arginine catabolic process to glutamate arginine catabolic process to proline via ornithine L-proline biosynthetic process visual perception | cytoplasm; mitochondrial matrix; mitochondrion; nucleoplasm | identical protein binding ornithine aminotransferase activity pyridoxal phosphate binding | Homo sapiens | 3D-structure Acetylation Alternative splicing Aminotransferase Direct protein sequencing Disease variant Mitochondrion Pyridoxal phosphate Reference proteome Transferase Transit peptide | MFSKLAHLQR | MFSKLAHLQRFAVLSRGVHSSVASATSVATKKTVQGPPTSDDIFEREYKYGAHNYHPLPVALERGKGIYLWDVEGRKYFDFLSSYSAVNQGHCHPKIVNALKSQVDKLTLTSRAFYNNVLGEYEEYITKLFNYHKVLPMNTGVEAGETACKLARKWGYTVKGIQKYKAKIVFAAGNFWGRTLSAISSSTDPTSYDGFGPFMPGFDIIPYNDLPALERALQDPNVAAFMVEPIQGEAGVVVPDPGYLMGVRELCTRHQVLFIADEIQTGLARTGRWLAVDYENVRPDIVLLGKALSGGLYPVSAVLCDDDIMLTIKPGEHG... | arginine catabolic process to glutamate arginine catabolic process to proline via ornithine L-proline biosynthetic process visual perception cytoplasm; mitochondrial matrix; mitochondrion; nucleoplasm identical protein binding ornithine aminotransferase activity pyridoxal phosphate binding Homo sapiens 3D-structure Ace... |
arginine catabolic process to glutamate arginine catabolic process to proline via ornithine L-proline biosynthetic process ornithine metabolic process | cytoplasm; mitochondrial matrix; nucleoplasm | identical protein binding N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity ornithine aminotransferase activity pyridoxal phosphate binding | Rattus norvegicus | Acetylation Aminotransferase Direct protein sequencing Mitochondrion Pyridoxal phosphate Reference proteome Transferase Transit peptide | MLSKLASLQT | MLSKLASLQTVAALRRGLRTSVASATSVATKKTEQGPPSSEYIFERESKYGAHNYHPLPVALERGKGIYMWDVEGRQYFDFLSAYGAVSQGHCHPKIIEAMKSQVDKLTLTSRAFYNNVLGEYEEYITKLFNYNKVLPMNTGVEAGETACKLARRWGYTVKGIQKYKAKIVFAVGNFWGRTLSAVSSSTDPTSYDGFGPFMPGFETIPYNDLPALERALQDPNVAAFMVEPIQGEAGVIVPDPGYLTGVRELCTRHQVLFIADEIQTGLARTGRWLAVDHENVRPDIVLLGKALSGGLYPVSAVLCDDDIMLTIKPGEHG... | arginine catabolic process to glutamate arginine catabolic process to proline via ornithine L-proline biosynthetic process ornithine metabolic process cytoplasm; mitochondrial matrix; nucleoplasm identical protein binding N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity ornithine aminotransferase activi... |
DNA synthesis involved in mitotic DNA replication nucleobase-containing compound metabolic process phosphorylation protein homotetramerization thymidine biosynthetic process thymidine metabolic process | cytosol; nucleus | ATP binding identical protein binding thymidine kinase activity zinc ion binding | Homo sapiens | 3D-structure Acetylation ATP-binding Cytoplasm DNA synthesis Kinase Metal-binding Nucleotide-binding Phosphoprotein Reference proteome Transferase Ubl conjugation Zinc | MSCINLPTVL | MSCINLPTVLPGSPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQYKCLVIKYAKDTRYSSSFCTHDRNTMEALPACLLRDVAQEALGVAVIGIDEGQFFPDIVEFCEAMANAGKTVIVAALDGTFQRKPFGAILNLVPLAESVVKLTAVCMECFREAAYTKRLGTEKEVEVIGGADKYHSVCRLCYFKKASGQPAGPDNKENCPVPGKPGEAVAARKLFAPQQILQCSPAN | DNA synthesis involved in mitotic DNA replication nucleobase-containing compound metabolic process phosphorylation protein homotetramerization thymidine biosynthetic process thymidine metabolic process cytosol; nucleus ATP binding identical protein binding thymidine kinase activity zinc ion binding Homo sapiens 3D-stru... |
DNA synthesis involved in mitotic DNA replication phosphorylation protein homotetramerization thymidine biosynthetic process thymidine metabolic process | cytosol; nucleus | ATP binding identical protein binding thymidine kinase activity zinc ion binding | Mus musculus | Acetylation Alternative splicing ATP-binding Cytoplasm DNA synthesis Kinase Metal-binding Nucleotide-binding Phosphoprotein Reference proteome Transferase Ubl conjugation Zinc | MSYINLPTVL | MSYINLPTVLPSSPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQYKCLVIKYAKDTRYSNSFSTHDRNTMDALPACMLRDVTQESLGVAVIGIDEGQFFPDIVDFCEMMANEGKTVIVAALDGTFQRKAFGSILNLVPLAESVVKLTAVCMECFREAAYTKRLGLEKEVEVIGGADKYHSVCRLCYFKKSSAQTAGSDNKNCLVLGQPGEALVVRKLFASQQVLQYNSAN | DNA synthesis involved in mitotic DNA replication phosphorylation protein homotetramerization thymidine biosynthetic process thymidine metabolic process cytosol; nucleus ATP binding identical protein binding thymidine kinase activity zinc ion binding Mus musculus Acetylation Alternative splicing ATP-binding Cytoplasm D... |
B cell proliferation complement activation complement activation, alternative pathway proteolysis response to bacterium | classical-complement-pathway C3/C5 convertase complex | serine-type endopeptidase activity | Mus musculus | Cleavage on pair of basic residues Complement alternate pathway Disulfide bond Glycoprotein Hydrolase Immunity Innate immunity Protease Reference proteome Repeat Secreted Serine protease Signal Sushi Zymogen | MESPQLCLVL | MESPQLCLVLLVLGFSSGGVSATPVLEARPQVSCSLEGVEIKGGSFQLLQGGQALEYLCPSGFYPYPVQTRTCRSTGSWSDLQTRDQKIVQKAECRAIRCPRPQDFENGEFWPRSPFYNLSDQISFQCYDGYVLRGSANRTCQENGRWDGQTAICDDGAGYCPNPGIPIGTRKVGSQYRLEDIVTYHCSRGLVLRGSQKRKCQEGGSWSGTEPSCQDSFMYDSPQEVAEAFLSSLTETIEGADAEDGHSPGEQQKRKIVLDPSGSMNIYLVLDGSDSIGSSNFTGAKRCLTNLIEKVASYGVRPRYGLLTYATVPKVLVR... | B cell proliferation complement activation complement activation, alternative pathway proteolysis response to bacterium classical-complement-pathway C3/C5 convertase complex serine-type endopeptidase activity Mus musculus Cleavage on pair of basic residues Complement alternate pathway Disulfide bond Glycoprotein Hydrol... |
apoptotic process defense response to bacterium granzyme-mediated programmed cell death signaling pathway killing of cells of another organism natural killer cell mediated cytotoxicity protein maturation proteolysis involved in protein catabolic process pyroptosis T cell mediated cytotoxicity | cytolytic granule; cytoplasm; cytosol; early endosome; extracellular space; intracellular membrane-bounded organelle | serine-type endopeptidase activity serine-type peptidase activity | Mus musculus | Apoptosis Cytolysis Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Lysosome Protease Reference proteome Secreted Serine protease Signal Zymogen | MKILLLLLTL | MKILLLLLTLSLASRTKAGEIIGGHEVKPHSRPYMALLSIKDQQPEAICGGFLIREDFVLTAAHCEGSIINVTLGAHNIKEQEKTQQVIPMVKCIPHPDYNPKTFSNDIMLLKLKSKAKRTRAVRPLNLPRRNVNVKPGDVCYVAGWGRMAPMGKYSNTLQEVELTVQKDRECESYFKNRYNKTNQICAGDPKTKRASFRGDSGGPLVCKKVAAGIVSYGYKDGSPPRAFTKVSSFLSWIKKTMKSS | apoptotic process defense response to bacterium granzyme-mediated programmed cell death signaling pathway killing of cells of another organism natural killer cell mediated cytotoxicity protein maturation proteolysis involved in protein catabolic process pyroptosis T cell mediated cytotoxicity cytolytic granule; cytopla... |
proteolysis sporulation resulting in formation of a cellular spore | extracellular region | metal ion binding serine-type endopeptidase activity | Bacillus subtilis | 3D-structure Autocatalytic cleavage Calcium Direct protein sequencing Hydrolase Metal-binding Protease Reference proteome Secreted Serine protease Signal Sporulation Zymogen | MRSKKLWISL | MRSKKLWISLLFALTLIFTMAFSNMSAQAAGKSSTEKKYIVGFKQTMSAMSSAKKKDVISEKGGKVQKQFKYVNAAAATLDEKAVKELKKDPSVAYVEEDHIAHEYAQSVPYGISQIKAPALHSQGYTGSNVKVAVIDSGIDSSHPDLNVRGGASFVPSETNPYQDGSSHGTHVAGTIAALNNSIGVLGVAPSASLYAVKVLDSTGSGQYSWIINGIEWAISNNMDVINMSLGGPTGSTALKTVVDKAVSSGIVVAAAAGNEGSSGSTSTVGYPAKYPSTIAVGAVNSSNQRASFSSAGSELDVMAPGVSIQSTLPGGTY... | proteolysis sporulation resulting in formation of a cellular spore extracellular region metal ion binding serine-type endopeptidase activity Bacillus subtilis 3D-structure Autocatalytic cleavage Calcium Direct protein sequencing Hydrolase Metal-binding Protease Reference proteome Secreted Serine protease Signal Sporula... |
antibiotic catabolic process response to antibiotic | periplasmic space | beta-lactamase activity zinc ion binding | Bacillus cereus | 3D-structure Antibiotic resistance Direct protein sequencing Hydrolase Metal-binding Periplasm Signal Zinc | MKKNTLLKVG | MKKNTLLKVGLCVGLLGTIQFVSTISSVQASQKVEKTVIKNETGTISISQLNKNVWVHTELGSFNGEAVPSNGLVLNTSKGLVLVDSSWDDKLTKELIEMVEKKFQKRVTDVIITHAHADRIGGIKTLKERGIKAHSTALTAELAKKNGYEEPLGDLQTVTNLKFGNMKVETFYPGKGHTEDNIVVWLPQYNILVGGCLVKSTSAKDLGNVADAYVNEWSTSIENVLKRYRNINAVVPGHGEVGDKGLLLHTLDLLK | antibiotic catabolic process response to antibiotic periplasmic space beta-lactamase activity zinc ion binding Bacillus cereus3D-structure Antibiotic resistance Direct protein sequencing Hydrolase Metal-binding Periplasm Signal Zinc MKKNTLLKVG MKKNTLLKVGLCVGLLGTIQFVSTISSVQASQKVEKTVIKNETGTISISQLNKNVWVHTELGSFNGEAVPSNGLVL... |
calcium ion import into sarcoplasmic reticulum calcium ion transport negative regulation of striated muscle contraction positive regulation of ATPase-coupled calcium transmembrane transporter activity positive regulation of calcium ion import into sarcoplasmic reticulum positive regulation of cardiac muscle cell contra... | endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment; H zone; I band; membrane; perinuclear region of cytoplasm; sarcoplasmic reticulum; sarcoplasmic reticulum membrane | ATP binding ATP hydrolysis activity calcium ion binding P-type calcium transporter activity | Oryctolagus cuniculus | 3D-structure Alternative splicing ATP-binding Calcium Calcium transport Direct protein sequencing Disulfide bond Endoplasmic reticulum Ion transport Magnesium Membrane Metal-binding Nucleotide-binding Phosphoprotein Reference proteome Sarcoplasmic reticulum Translocase Transmembrane Transmembrane helix Transport | MEAAHSKSTE | MEAAHSKSTEECLAYFGVSETTGLTPDQVKRHLEKYGHNELPAEEGKSLWELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILSIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVSTEIGKIRDQMAATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLA... | calcium ion import into sarcoplasmic reticulum calcium ion transport negative regulation of striated muscle contraction positive regulation of ATPase-coupled calcium transmembrane transporter activity positive regulation of calcium ion import into sarcoplasmic reticulum positive regulation of cardiac muscle cell contra... |
centriole replication centrosome cycle chromosome condensation eggshell chorion gene amplification Golgi organization mitotic cell cycle mitotic cytokinesis negative regulation of cell size positive regulation of cell population proliferation positive regulation of G2/M transition of mitotic cell cycle positive regulat... | euchromatin; Myb complex; nucleus; polytene chromosome | DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding | Drosophila melanogaster | Activator Chromosome DNA-binding Nucleus Phosphoprotein Reference proteome Repeat Repressor Transcription Transcription regulation | MASASTENGE | MASASTENGEELMNYGSNSDSEESEYSENEDTQVCDKDSQQNSNADSGYPLDSPELQDSKTTGQKGQNKSGKTSIGAVHPNYGFGKRWSKSEDVLLKQLVETHGENWEIIGPHFKDRLEQQVQQRWAKVLNPELIKGPWTRDEDDMVIKLVRNFGPKKWTLIARYLNGRIGKQCRERWHNHLNPNIKKTAWTEKEDEIIYQAHLELGNQWAKIAKRLPGRTDNAIKNHWNSTMRRKYDVERRSVNASGSDLKSSRTHLITLIKSGGISKCMNNMQHNKESGGEAVNKSENADGASVTAVKGGDLAQESQDDHQKGSNLAH... | centriole replication centrosome cycle chromosome condensation eggshell chorion gene amplification Golgi organization mitotic cell cycle mitotic cytokinesis negative regulation of cell size positive regulation of cell population proliferation positive regulation of G2/M transition of mitotic cell cycle positive regulat... |
negative regulation of gene expression positive regulation of DNA-templated transcription positive regulation of gene expression positive regulation of miRNA transcription positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II | chromatin; nucleolus; nucleoplasm; nucleus | DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific kinase binding protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence... | Homo sapiens | 3D-structure Activator Disease variant DNA-binding Nucleus Phosphoprotein Proto-oncogene Reference proteome Transcription Transcription regulation | MPSCSTSTMP | MPSCSTSTMPGMICKNPDLEFDSLQPCFYPDEDDFYFGGPDSTPPGEDIWKKFELLPTPPLSPSRGFAEHSSEPPSWVTEMLLENELWGSPAEEDAFGLGGLGGLTPNPVILQDCMWSGFSAREKLERAVSEKLQHGRGPPTAGSTAQSPGAGAASPAGRGHGGAAGAGRAGAALPAELAHPAAECVDPAVVFPFPVNKREPAPVPAAPASAPAAGPAVASGAGIAAPAGAPGVAPPRPGGRQTSGGDHKALSTSGEDTLSDSDDEDDEEEDEEEEIDVVTVEKRRSSSNTKAVTTFTITVRPKNAALGPGRAQSSELIL... | negative regulation of gene expression positive regulation of DNA-templated transcription positive regulation of gene expression positive regulation of miRNA transcription positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II chromatin; nucleolus; nucleoplasm; nucleu... |
G protein-coupled receptor signaling pathway hippocampus development male gonad development negative regulation of protein phosphorylation positive regulation of canonical NF-kappaB signal transduction positive regulation of cell population proliferation positive regulation of DNA replication positive regulation of ino... | cell surface; plasma membrane | angiotensin receptor activity angiotensin type II receptor activity G protein-coupled receptor activity peptide binding | Homo sapiens | Cell membrane G-protein coupled receptor Glycoprotein Membrane Proto-oncogene Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MDGSNVTSFV | MDGSNVTSFVVEEPTNISTGRNASVGNAHRQIPIVHWVIMSISPVGFVENGILLWFLCFRMRRNPFTVYITHLSIADISLLFCIFILSIDYALDYELSSGHYYTIVTLSVTFLFGYNTGLYLLTAISVERCLSVLYPIWYRCHRPKYQSALVCALLWALSCLVTTMEYVMCIDREEESHSRNDCRAVIIFIAILSFLVFTPLMLVSSTILVVKIRKNTWASHSSKLYIVIMVTIIIFLIFAMPMRLLYLLYYEYWSTFGNLHHISLLFSTINSSANPFIYFFVGSSKKKRFKESLKVVLTRAFKDEMQPRRQKDNCNTVT... | G protein-coupled receptor signaling pathway hippocampus development male gonad development negative regulation of protein phosphorylation positive regulation of canonical NF-kappaB signal transduction positive regulation of cell population proliferation positive regulation of DNA replication positive regulation of ino... |
angiogenesis cell-cell adhesion cell-cell signaling cytoskeleton organization focal adhesion assembly heterotypic cell-cell adhesion integrin-mediated signaling pathway negative regulation of axonogenesis negative regulation of cell migration negative regulation of neuron projection regeneration negative regulation of ... | apical plasma membrane; axolemma; cell surface; dendrite; dendrite membrane; endoplasmic reticulum; external side of plasma membrane; extracellular exosome; extracellular region; focal adhesion; growth cone; membrane raft; neuronal cell body membrane; plasma membrane | GPI anchor binding GTPase activator activity integrin binding protein kinase binding | Homo sapiens | Cell membrane Disulfide bond Glycoprotein GPI-anchor Immunoglobulin domain Lipoprotein Membrane Phosphoprotein Pyrrolidone carboxylic acid Reference proteome Signal | MNLAISIALL | MNLAISIALLLTVLQVSRGQKVTSLTACLVDQSLRLDCRHENTSSSPIQYEFSLTRETKKHVLFGTVGVPEHTYRSRTNFTSKYNMKVLYLSAFTSKDEGTYTCALHHSGHSPPISSQNVTVLRDKLVKCEGISLLAQNTSWLLLLLLSLSLLQATDFMSL | angiogenesis cell-cell adhesion cell-cell signaling cytoskeleton organization focal adhesion assembly heterotypic cell-cell adhesion integrin-mediated signaling pathway negative regulation of axonogenesis negative regulation of cell migration negative regulation of neuron projection regeneration negative regulation of ... |
cell-cell adhesion heterotypic cell-cell adhesion negative regulation of cell population proliferation negative regulation of interleukin-6 production negative regulation of macrophage activation negative regulation of macrophage migration negative regulation of matrix metallopeptidase secretion negative regulation of ... | axon; cell body; cell surface; neuron projection; neuronal cell body; plasma membrane | cell-cell adhesion mediator activity protein binding involved in heterotypic cell-cell adhesion | Rattus norvegicus | Cell membrane Disulfide bond Glycoprotein Immunoglobulin domain Membrane Reference proteome Signal Transmembrane Transmembrane helix | MGSPVFRRPF | MGSPVFRRPFCHLSTYSLLWAIAAVALSTAQVEVVTQDERKLLHTTASLRCSLKTTQEPLIVTWQKKKAVGPENMVTYSKAHGVVIQPTYKDRINITELGLLNTSITFWNTTLDDEGCYMCLFNMFGSGKVSGTACLTLYVQPIVHLHYNYFEDHLNITCSATARPAPAISWKGTGSGIENSTESHSHSNGTTSVTSILRVKDPKTQVGKEVICQVLYLGNVIDYKQSLDKGFWFSVPLLLSIVSLVILLVLISILLYWKRHRNQERGESSQGMQRMK | cell-cell adhesion heterotypic cell-cell adhesion negative regulation of cell population proliferation negative regulation of interleukin-6 production negative regulation of macrophage activation negative regulation of macrophage migration negative regulation of matrix metallopeptidase secretion negative regulation of ... |
adaptive immune response antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of peptide antigen negative regulation of T cell proliferation peptide antigen assembly with MHC class II protein complex positive regulation... | external side of plasma membrane; late endosome membrane; lysosomal membrane; lysosome; MHC class II protein complex; plasma membrane | MHC class II protein complex binding peptide antigen binding protein-containing complex binding | Mus musculus | Adaptive immunity Disulfide bond Glycoprotein Immunity Membrane MHC II Reference proteome Transmembrane Transmembrane helix | GIVVYQSPGD | GIVVYQSPGDIGQYTHEFDGDEWFYVDLDKKETVWMLPEFGQLTSFDPQGGLQNIATGKHNLGGWTKRSNFTPATNEAPQATVFPKSPVLLGQPNTLICFVDNIFPPVINITWLRNSKSVTDGVYETSFLVNRDHSFHKLSYLTFIPSDDDIYDCKVEHWGLDEPVLKHWEPEIPAPMSELTETVVCALGLSVGLVGIVVGTIFIIQGLRSGGTSRPPGPL | adaptive immune response antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of peptide antigen negative regulation of T cell proliferation peptide antigen assembly with MHC class II protein complex positive regulation... |
adaptive immune response antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of peptide antigen negative regulation of T cell proliferation peptide antigen assembly with MHC class II protein complex positive regulation... | external side of plasma membrane; late endosome membrane; lysosomal membrane; lysosome; MHC class II protein complex; plasma membrane | MHC class II protein complex binding peptide antigen binding protein-containing complex binding | Mus musculus | 3D-structure Adaptive immunity Disulfide bond Glycoprotein Immunity Membrane MHC II Reference proteome Signal Transmembrane Transmembrane helix | MPCSRALILG | MPCSRALILGVLALNTMLSLCGGEDDIEADHVGFYGTTVYQSPGDIGQYTHEFDGDELFYVDLDKKKTVWRLPEFGQLILFEPQGGLQNIAAEKHNLGILTKRSNFTPATNEAPQATVFPKSPVLLGQPNTLICFVDNIFPPVINITWLRNSKSVTDGVYETSFLVNRDHSFHKLSYLTFIPSDDDIYDCKVEHWGLEEPVLKHWEPEIPAPMSELTETVVCALGLSVGLVGIVVGTIFIIQGLRSGGTSRHPGPL | adaptive immune response antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of peptide antigen negative regulation of T cell proliferation peptide antigen assembly with MHC class II protein complex positive regulation... |
adaptive immune response antigen processing and presentation of exogenous peptide antigen via MHC class II peptide antigen assembly with MHC class II protein complex positive regulation of immune response positive regulation of T cell activation | cell surface; external side of plasma membrane; immunological synapse; late endosome membrane; lysosomal membrane; MHC class II protein complex; plasma membrane | CD4 receptor binding MHC class II protein complex binding MHC class II receptor activity peptide antigen binding polysaccharide binding T cell receptor binding | Mus musculus | 3D-structure Adaptive immunity Disulfide bond Glycoprotein Immunity Membrane MHC II Reference proteome Signal Transmembrane Transmembrane helix Ubl conjugation | MVWLPRVPCV | MVWLPRVPCVAAVILLLTVLSPPMALVRDSRPWFLEYCKSECHFYNGTQRVRLLERYFYNLEENLRFDSDVGEFHAVTELGRPDAENWNSQPEFLEQKRAEVDTVCRHNYEISDKFLVRRRVEPTVTVYPTKTQPLEHHNLLVCSVSDFYPGNIEVRWFRNGKEEKTGIVSTGLVRNGDWTFQTLVMLETVPQSGEVYTCQVEHPSLTDPVTVEWKAQSTSAQNKMLSGVGGFVLGLLFLGAGLFIYFRNQKGQSGLQPTGLLS | adaptive immune response antigen processing and presentation of exogenous peptide antigen via MHC class II peptide antigen assembly with MHC class II protein complex positive regulation of immune response positive regulation of T cell activation cell surface; external side of plasma membrane; immunological synapse; lat... |
adaptive immune response alpha-beta T cell activation cell surface receptor signaling pathway positive thymic T cell selection T cell receptor signaling pathway | alpha-beta T cell receptor complex; clathrin-coated endocytic vesicle membrane; cytoplasm; external side of plasma membrane; plasma membrane; T cell receptor complex | identical protein binding transmembrane signaling receptor activity | Homo sapiens | 3D-structure Adaptive immunity Alternative splicing Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Immunity Membrane Phosphoprotein Receptor Reference proteome SCID Signal Transmembrane Transmembrane helix | MEHSTFLSGL | MEHSTFLSGLVLATLLSQVSPFKIPIEELEDRVFVNCNTSITWVEGTVGTLLSDITRLDLGKRILDPRGIYRCNGTDIYKDKESTVQVHYRMCQSCVELDPATVAGIIVTDVIATLLLALGVFCFAGHETGRLSGAADTQALLRNDQVYQPLRDRDDAQYSHLGGNWARNK | adaptive immune response alpha-beta T cell activation cell surface receptor signaling pathway positive thymic T cell selection T cell receptor signaling pathway alpha-beta T cell receptor complex; clathrin-coated endocytic vesicle membrane; cytoplasm; external side of plasma membrane; plasma membrane; T cell receptor c... |
adaptive immune response cell surface receptor signaling pathway positive thymic T cell selection protein-containing complex assembly T cell activation | alpha-beta T cell receptor complex; external side of plasma membrane; plasma membrane; T cell receptor complex | identical protein binding transmembrane signaling receptor activity | Mus musculus | Adaptive immunity Disulfide bond Glycoprotein Immunity Membrane Phosphoprotein Receptor Reference proteome Signal Transmembrane Transmembrane helix | MEHSGILASL | MEHSGILASLILIAVLPQGSPFKIQVTEYEDKVFVTCNTSVMHLDGTVEGWFAKNKTLNLGKGVLDPRGIYLCNGTEQLAKVVSSVQVHYRMCQNCVELDSGTMAGVIFIDLIATLLLALGVYCFAGHETGRPSGAAEVQALLKNEQLYQPLRDREDTQYSRLGGNWPRNKKS | adaptive immune response cell surface receptor signaling pathway positive thymic T cell selection protein-containing complex assembly T cell activation alpha-beta T cell receptor complex; external side of plasma membrane; plasma membrane; T cell receptor complex identical protein binding transmembrane signaling recepto... |
brown fat cell differentiation enucleate erythrocyte differentiation heart development hydrogen peroxide mediated signaling pathway oxygen transport removal of superoxide radicals response to hormone response to hydrogen peroxide response to hypoxia | sarcoplasm | heme binding metal ion binding nitrite reductase activity oxygen binding oxygen carrier activity peroxidase activity | Mus musculus | Direct protein sequencing Heme Iron Metal-binding Muscle protein Oxygen transport Phosphoprotein Reference proteome Transport | MGLSDGEWQL | MGLSDGEWQLVLNVWGKVEADLAGHGQEVLIGLFKTHPETLDKFDKFKNLKSEEDMKGSEDLKKHGCTVLTALGTILKKKGQHAAEIQPLAQSHATKHKIPVKYLEFISEIIIEVLKKRHSGDFGADAQGAMSKALELFRNDIAAKYKELGFQG | brown fat cell differentiation enucleate erythrocyte differentiation heart development hydrogen peroxide mediated signaling pathway oxygen transport removal of superoxide radicals response to hormone response to hydrogen peroxide response to hypoxia sarcoplasm heme binding metal ion binding nitrite reductase activity o... |
oxygen transport | extracellular region | chloride ion binding copper ion binding oxidoreductase activity oxygen carrier activity | Limulus polyphemus | 3D-structure Copper Direct protein sequencing Disulfide bond Glycoprotein Metal-binding Oxygen transport Secreted Transport | TLHDKQIRVC | TLHDKQIRVCHLFEQLSSATVIGDGDKHKHSDRLKNVGKLQPGAIFSCFHPDHLEEARHLYEVFWEAGDFNDFIEIAKEARTFVNEGLFAFAAEVAVLHRDDCKGLYVPPVQEIFPDKFIPSAAINEAFKKAHVRPEFDESPILVDVQDTGNILDPEYRLAYYREDVGINAHHWHWHLVYPSTWNPKYFGKKKDRKGELFYYMHQQMCARYDCERLSNGMHRMLPFNNFDEPLAGYAPHLTHVASGKYYSPRPDGLKLRDLGDIEISEMVRMRERILDSIHLGYVISEDGSHKTLDELHGTDILGALVESSYESVNHEYY... | oxygen transport extracellular region chloride ion binding copper ion binding oxidoreductase activity oxygen carrier activity Limulus polyphemus 3D-structure Copper Direct protein sequencing Disulfide bond Glycoprotein Metal-binding Oxygen transport Secreted Transport TLHDKQIRVC TLHDKQIRVCHLFEQLSSATVIGDGDKHKHSDRLKNVGKL... |
alternative mRNA splicing, via spliceosome amyloid fibril formation cellular response to epidermal growth factor stimulus cellular response to glucose starvation cellular response to organic substance cellular response to potassium ion cellular response to sodium arsenite import into nucleus localization lung developme... | catalytic step 2 spliceosome; cytoplasm; intracellular non-membrane-bounded organelle; nucleoplasm; nucleoplasmic periphery of the nuclear pore complex; nucleus; ribonucleoprotein complex; spliceosomal complex; synapse | DNA binding DNA/DNA annealing activity G-rich strand telomeric DNA binding miRNA binding molecular condensate scaffold activity mRNA 3'-UTR binding mRNA binding pre-mRNA binding protein domain specific binding RNA binding RNA strand annealing activity sequence-specific mRNA binding single-stranded DNA binding single-st... | Rattus norvegicus | Acetylation Cytoplasm Direct protein sequencing Isopeptide bond Methylation mRNA processing mRNA splicing mRNA transport Nucleus Phosphoprotein Reference proteome Repeat Ribonucleoprotein RNA-binding Spliceosome Transport Ubl conjugation | MSKSESPKEP | MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALCKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYGSGRRF | alternative mRNA splicing, via spliceosome amyloid fibril formation cellular response to epidermal growth factor stimulus cellular response to glucose starvation cellular response to organic substance cellular response to potassium ion cellular response to sodium arsenite import into nucleus localization lung developme... |
ectoderm development intermediate filament organization keratinization | cytosol; extracellular exosome; keratin filament | structural constituent of cytoskeleton structural constituent of skin epidermis | Homo sapiens | Acetylation Coiled coil Direct protein sequencing Disease variant Ectodermal dysplasia Intermediate filament Keratin Palmoplantar keratoderma Reference proteome | MASTSTTIRS | MASTSTTIRSHSSSRRGFSANSARLPGVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDNIVGERGRLDSELRNMQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVL... | ectoderm development intermediate filament organization keratinization cytosol; extracellular exosome; keratin filament structural constituent of cytoskeleton structural constituent of skin epidermis Homo sapiens Acetylation Coiled coil Direct protein sequencing Disease variant Ectodermal dysplasia Intermediate filamen... |
complement activation, lectin pathway establishment of skin barrier fibrinolysis intermediate filament organization keratinization negative regulation of inflammatory response peptide cross-linking protein heterotetramerization regulation of angiogenesis response to oxidative stress | blood microparticle; collagen-containing extracellular matrix; cornified envelope; cytoplasm; cytoskeleton; cytosol; extracellular exosome; extracellular region; extracellular space; ficolin-1-rich granule lumen; keratin filament; membrane; nucleus | carbohydrate binding protein heterodimerization activity signaling receptor activity structural constituent of skin epidermis | Homo sapiens | 3D-structure Cell membrane Citrullination Coiled coil Cytoplasm Direct protein sequencing Disease variant Ichthyosis Intermediate filament Keratin Membrane Methylation Palmoplantar keratoderma Phosphoprotein Reference proteome | MSRQFSSRSG | MSRQFSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLLQPLNVEIDPEIQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYMTKVDLQAKLDNLQQEIDFLTALYQ... | complement activation, lectin pathway establishment of skin barrier fibrinolysis intermediate filament organization keratinization negative regulation of inflammatory response peptide cross-linking protein heterotetramerization regulation of angiogenesis response to oxidative stress blood microparticle; collagen-contai... |
actin filament organization cardiac muscle contraction | actin cytoskeleton; actin filament; cytoplasm; plasma membrane | actin filament binding cytoskeletal protein binding identical protein binding protein heterodimerization activity protein homodimerization activity | Gallus gallus | 3D-structure Acetylation Actin-binding Alternative splicing Coiled coil Cytoplasm Cytoskeleton Direct protein sequencing Muscle protein Reference proteome | MDAIKKKMQM | MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEERSKQLEDELVALQKKLKGTEDELDKYSESLKDAQEKLELADKKATDAESEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAQKDEEKMEIQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERAEERAELSESKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLTDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI | actin filament organization cardiac muscle contraction actin cytoskeleton; actin filament; cytoplasm; plasma membrane actin filament binding cytoskeletal protein binding identical protein binding protein heterodimerization activity protein homodimerization activity Gallus gallus 3D-structure Acetylation Actin-binding A... |
adaptive thermogenesis axonogenesis cell adhesion central nervous system development learning or memory memory positive regulation of canonical NF-kappaB signal transduction positive regulation of cell population proliferation positive regulation of neuron differentiation regulation of neuronal synaptic plasticity symp... | cytoplasm; cytosol; extracellular region; extracellular space; intracellular membrane-bounded organelle; neuronal cell body; nucleoplasm; nucleus; perinuclear region of cytoplasm; ruffle | calcium ion binding calcium-dependent protein binding identical protein binding ion binding protein homodimerization activity RAGE receptor binding S100 protein binding tau protein binding zinc ion binding | Homo sapiens | 3D-structure Acetylation Calcium Cell adhesion Cytoplasm Direct protein sequencing Metal-binding Nucleus Reference proteome Repeat Secreted Zinc | MSELEKAMVA | MSELEKAMVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDNDGDGECDFQEFMAFVAMVTTACHEFFEHE | adaptive thermogenesis axonogenesis cell adhesion central nervous system development learning or memory memory positive regulation of canonical NF-kappaB signal transduction positive regulation of cell population proliferation positive regulation of neuron differentiation regulation of neuronal synaptic plasticity symp... |
biomineral tissue development calcium ion import calcium ion transmembrane transport | basement membrane; collagen-containing extracellular matrix; cytoplasm; cytosol; endosome; extracellular membrane-bounded organelle; extracellular space; intracellular membrane-bounded organelle; melanosome; membrane; nucleus; plasma membrane; vesicle | calcium channel activity calcium ion binding calcium-dependent phospholipid binding cytoskeletal protein binding phosphatidylinositol-4,5-bisphosphate binding phosphatidylserine binding phospholipase A2 inhibitor activity protease binding virion binding | Bos taurus | 3D-structure Acetylation Annexin Basement membrane Calcium Calcium/phospholipid-binding Extracellular matrix Isopeptide bond Phosphoprotein Reference proteome Repeat Secreted Ubl conjugation | MSTVHEILCK | MSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNEQRQDIAFAYQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIVSDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKKKYGKSLYYYIQ... | biomineral tissue development calcium ion import calcium ion transmembrane transport basement membrane; collagen-containing extracellular matrix; cytoplasm; cytosol; endosome; extracellular membrane-bounded organelle; extracellular space; intracellular membrane-bounded organelle; melanosome; membrane; nucleus; plasma m... |
female pregnancy lactation response to estradiol response to nutrient levels response to steroid hormone vitamin D metabolic process | axon; cytoplasm; extracellular space; perinuclear region of cytoplasm | actin binding calcidiol binding vitamin D binding vitamin transmembrane transporter activity | Rattus norvegicus | Actin-binding Direct protein sequencing Disulfide bond Glycoprotein Phosphoprotein Reference proteome Repeat Secreted Signal Transport Vitamin D | MKRVLVLLLA | MKRVLVLLLALAFGHALERGRDYEKDKVCQELSTLGKDDFRSLSLILYSRKFPSSTFEQVSQLVKEVVSLTEECCAEGADPNCYDTRTSELSIKSCESDAPFPVHPGTSECCTKEGLERKLCMAALSHQPQEFPAYVEPTNDEICEAFRKDPKGFADQFLFEYSSNYGQAPLPLLVGYTKSYLSMVGSCCTSAKPTVCFLKERLQMKQLLLLTTMSNRVCSQYAAYGKEKSRMSHLIKLAQKVPTANLEDVLPLAEDLTEILSRCCKSTSEDCMARELPEHTLKICGNLSKKNSKFEECCYETTPMGIFMCSYFMPTAEP... | female pregnancy lactation response to estradiol response to nutrient levels response to steroid hormone vitamin D metabolic process axon; cytoplasm; extracellular space; perinuclear region of cytoplasm actin binding calcidiol binding vitamin D binding vitamin transmembrane transporter activity Rattus norvegicus Actin-... |
antibacterial humoral response antimicrobial humoral immune response mediated by antimicrobial peptide coagulation insemination killing of cells of another organism negative regulation of calcium ion import negative regulation of flagellated sperm motility positive regulation of serine-type endopeptidase activity sperm... | extracellular exosome; extracellular region; extracellular space; nucleus; protein-containing complex | zinc ion binding | Homo sapiens | 3D-structure Alternative splicing Direct protein sequencing Disulfide bond Pyrrolidone carboxylic acid Reference proteome Repeat Secreted Signal | MKPNIIFVLS | MKPNIIFVLSLLLILEKQAAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEE... | antibacterial humoral response antimicrobial humoral immune response mediated by antimicrobial peptide coagulation insemination killing of cells of another organism negative regulation of calcium ion import negative regulation of flagellated sperm motility positive regulation of serine-type endopeptidase activity sperm... |
phosphorylation | host cell nucleus; viral tegument | ATP binding protein serine kinase activity protein serine/threonine kinase activity | Human herpesvirus 1 | ATP-binding Host nucleus Host-virus interaction Kinase Nucleotide-binding Reference proteome Serine/threonine-protein kinase Transferase Virion Virion tegument | MDESRRQRPA | MDESRRQRPAGHVAANLSPQGARQRSFKDWLASYVHSNPHGASGRPSGPSLQDAAVSRSSHGSRHRSGLRERLRAGLSRWRMSRSSHRRASPETPGTAAKLNRPPLRRSQAALTAPPSSPSHILTLTRIRKLCSPVFAINPALHYTTLEIPGARSFGGSGGYGDVQLIREHKLAVKTIKEKEWFAVELIATLLVGECVLRAGRTHNIRGFIAPLGFSLQQRQIVFPAYDMDLGKYIGQLASLRTTNPSVSTALHQCFTELARAVVFLNTTCGISHLDIKCANILVMLRSDAVSLRRAVLADFSLVTLNSNSTIARGQFCL... | phosphorylation host cell nucleus; viral tegument ATP binding protein serine kinase activity protein serine/threonine kinase activity Human herpesvirus 1 ATP-binding Host nucleus Host-virus interaction Kinase Nucleotide-binding Reference proteome Serine/threonine-protein kinase Transferase Virion Virion tegument MDES... |
DNA-templated transcription termination | virion component | GTP binding inorganic triphosphate phosphatase activity metal ion binding mRNA 5'-cap (guanine-N7-)-methyltransferase activity mRNA 5'-phosphatase activity mRNA guanylyltransferase activity polynucleotide 5'-phosphatase activity RNA binding | Vaccinia virus ) | 3D-structure Direct protein sequencing GTP-binding Hydrolase Magnesium Metal-binding Methyltransferase mRNA capping mRNA processing Multifunctional enzyme Nucleotide-binding Nucleotidyltransferase Reference proteome RNA-binding S-adenosyl-L-methionine Transcription Transcription regulation Transcription termination Tra... | MDANVVSSST | MDANVVSSSTIATYIDALAKNASELEQRSTAYEINNELELVFIKPPLITLTNVVNISTIQESFIRFTVTNKEGVKIRTKIPLSKVHGLDVKNVQLVDAIDNIVWEKKSLVTENRLHKECLLRLSTEERHIFLDYKKYGSSIRLELVNLIQAKTKNFTIDFKLKYFLGSGAQSKSSLLHAINHPKSRPNTSLEIEFTPRDNETVPYDELIKELTTLSRHIFMASPENVILSPPINAPIKTFMLPKQDIVGLDLENLYAVTKTDGIPITIRVTSNGLYCYFTHLGYIIRYPVKRIIDSEVVVFGEAVKDKNWTVYLIKLIEP... | DNA-templated transcription termination virion component GTP binding inorganic triphosphate phosphatase activity metal ion binding mRNA 5'-cap (guanine-N7-)-methyltransferase activity mRNA 5'-phosphatase activity mRNA guanylyltransferase activity polynucleotide 5'-phosphatase activity RNA binding Vaccinia virus )3D-s... |
DNA replication, synthesis of RNA primer viral DNA genome replication | host cell cytoplasm | ATP binding DNA primase activity helicase activity ribonucleoside triphosphate phosphatase activity | Vaccinia virus ) | ATP-binding Helicase Host cytoplasm Hydrolase Nucleotide-binding Reference proteome | MDAAIRGNDV | MDAAIRGNDVIFVLKTIGVPSACRQNEDPRFVEAFKCDELERYIENNPECTLFESLRDEEAYSIVRIFMDVDLDACLDEIDYLTAIQDFIIEVSNCVARFAFTECGAIHENVIKSMRSNFSLTKSTNRDKTSFHIIFLDTYTTMDTLIAMKRTLLELSRSSENPLTRSIDTAVYRRKTTLRVVGTRKNPNCDTIHVMQPPHDNIEDYLFTYVDMNNNSYYFSLQQRLEDLVPDKLWEPGFISFEDAIKRVSKIFINSIINFNDLDENNFTTVPLVIDYVTPCALCKKRSHKHPHQLSLENGAIRIYKTGNPHSCKVKIVP... | DNA replication, synthesis of RNA primer viral DNA genome replication host cell cytoplasm ATP binding DNA primase activity helicase activity ribonucleoside triphosphate phosphatase activity Vaccinia virus )ATP-binding Helicase Host cytoplasm Hydrolase Nucleotide-binding Reference proteome MDAAIRGNDV MDAAIRGNDVIFVLKTI... |
negative regulation of CD4 production perturbation by virus of host immune response regulation of calcium-mediated signaling suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC cla... | extracellular region; host cell Golgi membrane; host cell plasma membrane; membrane; virion component | ATPase binding CD4 receptor binding GTP binding MHC class I protein binding protein kinase binding SH3 domain binding signaling receptor binding thioesterase binding | Human immunodeficiency virus type 1 group M subtype B | 3D-structure AIDS Apoptosis Early protein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host autophagy by virus Inhibition of host MHC class I molecule presentation by virus Inhibition of host MHC class II molecule present... | MGGKWSKSSV | MGGKWSKSSVVGWPAVRERMRRAEPAADGVGAASRDLEKHGAITSSNTAANNAACAWLEAQEEEKVGFPVTPQVPLRPMTYKAAVDLSHFLKEKGGLEGLIHSQRRQDILDLWIYHTQGYFPDWQNYTPGPGIRYPLTFGWCYKLVPVEPEKLEEANKGENTSLLHPVSLHGMDDPEREVLEWRFDSRLAFHHVARELHPEYFKNC | negative regulation of CD4 production perturbation by virus of host immune response regulation of calcium-mediated signaling suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC cla... |
DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by viru... | extracellular region; host cell cytoplasm; host cell nucleolus | actinin binding cyclin binding metal ion binding protein domain specific binding protein serine/threonine phosphatase inhibitor activity RNA-binding transcription regulator activity trans-activation response element binding | Human immunodeficiency virus type 1 group M subtype B | 3D-structure Acetylation Activator AIDS Alternative splicing Apoptosis Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Isopeptide bond Metal-binding Methylation Modulation of host chromatin by virus Modulation... | MEPVDPRLEP | MEPVDPRLEPWKHPGSQPKTACTNCYCKKCCFHCQVCFITKALGISYGRKKRRQRRRAPQGSQTHQVSLSKQPTSQSRGDPTGPKE | DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by viru... |
microtubule cytoskeleton organization mitotic cell cycle negative regulation of microtubule polymerization | axoneme; cytoplasm; cytosol; extracellular exosome; intercellular bridge; internode region of axon; microtubule; microtubule cytoskeleton; mitotic spindle; myelin sheath; neuronal cell body; nucleus | calcium ion binding GTP binding GTPase activity structural constituent of cytoskeleton | Homo sapiens | Cytoplasm Cytoskeleton Direct protein sequencing Disease variant Dystonia GTP-binding Isopeptide bond Leukodystrophy Magnesium Metal-binding Microtubule Nucleotide-binding Phosphoprotein Reference proteome | MREIVHLQAG | MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGNYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGR... | microtubule cytoskeleton organization mitotic cell cycle negative regulation of microtubule polymerization axoneme; cytoplasm; cytosol; extracellular exosome; intercellular bridge; internode region of axon; microtubule; microtubule cytoskeleton; mitotic spindle; myelin sheath; neuronal cell body; nucleus calcium ion bi... |
calcium ion transport intracellular calcium ion homeostasis regulation of long-term synaptic potentiation regulation of presynaptic cytosolic calcium ion concentration sensory perception of pain | cytosol; dendrite; dendritic spine; nucleus; postsynaptic membrane; synapse; terminal bouton; vesicle membrane | calcium ion binding vitamin D binding | Gallus gallus | Acetylation Calcium Direct protein sequencing Metal-binding Reference proteome Repeat Vitamin D | MTAETHLQGV | MTAETHLQGVEISAAQFFEIWHHYDSDGNGYMDGKELQNFIQELQQARKKAGLDLTPEMKAFVDQYGKATDGKIGIVELAQVLPTEENFLLFFRCQQLKSSEDFMQTWRKYDSDHSGFIDSEELKSFLKDLLQKANKQIEDSKLTEYTEIMLRMFDANNDGKLELTELARLLPVQENFLIKFQGVKMCAKEFNKAFEMYDQDGNGYIDENELDALLKDLCEKNKKELDINNLATYKKSIMALSDGGKLYRAELALILCAEEN | calcium ion transport intracellular calcium ion homeostasis regulation of long-term synaptic potentiation regulation of presynaptic cytosolic calcium ion concentration sensory perception of pain cytosol; dendrite; dendritic spine; nucleus; postsynaptic membrane; synapse; terminal bouton; vesicle membrane calcium ion bi... |
arachidonic acid secretion lipid catabolic process phospholipid metabolic process | extracellular region | calcium ion binding phospholipase A2 activity toxin activity | Agkistrodon piscivorus piscivorus | 3D-structure Direct protein sequencing Disulfide bond Myotoxin Secreted Toxin | SVLELGKMIL | SVLELGKMILQETGKNAITSYGSYGCNCGWGHRGQPKDATDRCCFVHKCCYKKLTDCNHKTDRYSYSWKNKAIICEEKNPCLKEMCECDKAVAICLRENLDTYNKKYKAYFKLKCKKPDTC | arachidonic acid secretion lipid catabolic process phospholipid metabolic process extracellular region calcium ion binding phospholipase A2 activity toxin activity Agkistrodon piscivorus piscivorus 3D-structure Direct protein sequencing Disulfide bond Myotoxin Secreted Toxin SVLELGKMIL SVLELGKMILQETGKNAITSYGSYGCNCGWGHR... |
maintenance of blood-brain barrier MAPK cascade membrane organization myelination negative regulation of axonogenesis negative regulation of heterotypic cell-cell adhesion positive regulation of chemokine (C-X-C motif) ligand 2 production positive regulation of interleukin-6 production response to progesterone response... | cell periphery; cell projection; cell surface; compact myelin; cytoplasm; internode region of axon; myelin sheath; neuronal cell body; nucleus; plasma membrane; protein-containing complex | calmodulin binding lipid binding protease binding structural constituent of myelin sheath | Mus musculus | 3D-structure Acetylation Alternative splicing Autoimmune encephalomyelitis Cell membrane Citrullination Cytoplasm Direct protein sequencing Membrane Methylation Nucleus Phosphoprotein Reference proteome | MGNHSGKREL | MGNHSGKRELSAEKASKDGEIHRGEAGKKRSVGKLSQTASEDSDVFGEADAIQNNGTSAEDTAVTDSKHTADPKNNWQGAHPADPGNRPHLIRLFSRDAPGREDNTFKDRPSESDELQTIQEDPTAASGGLDVMASQKRPSQRSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFSGDRGAPKRGSGKDSHTRTTHYGSLPQKSQHGRTQDENPVVHFFKNIVTPRTPPPSQGKGGRDSRSGSPMARR | maintenance of blood-brain barrier MAPK cascade membrane organization myelination negative regulation of axonogenesis negative regulation of heterotypic cell-cell adhesion positive regulation of chemokine (C-X-C motif) ligand 2 production positive regulation of interleukin-6 production response to progesterone response... |
carbohydrate phosphorylation galactose catabolic process via UDP-galactose galactose metabolic process positive regulation of transcription by galactose positive regulation of transcription from RNA polymerase II promoter by galactose | cytoplasm; cytosol; nucleus; transcription regulator complex | ATP binding galactokinase activity | Saccharomyces cerevisiae | 3D-structure ATP-binding Carbohydrate metabolism Direct protein sequencing Galactose metabolism Kinase Nucleotide-binding Phosphoprotein Reference proteome Transferase | MTKSHSEEVI | MTKSHSEEVIVPEFNSSAKELPRPLAEKCPSIIKKFISAYDAKPDFVARSPGRVNLIGEHIDYCDFSVLPLAIDFDMLCAVKVLNEKNPSITLINADPKFAQRKFDLPLDGSYVTIDPSVSDWSNYFKCGLHVAHSFLKKLAPERFASAPLAGLQVFCEGDVPTGSGLSSSAAFICAVALAVVKANMGPGYHMSKQNLMRITVVAEHYVGVNNGGMDQAASVCGEEDHALYVEFKPQLKATPFKFPQLKNHEISFVIANTLVVSNKFETAPTNYNLRVVEVTTAANVLAATYGVVLLSGKEGSSTNKGNLRDFMNVYYAR... | carbohydrate phosphorylation galactose catabolic process via UDP-galactose galactose metabolic process positive regulation of transcription by galactose positive regulation of transcription from RNA polymerase II promoter by galactose cytoplasm; cytosol; nucleus; transcription regulator complex ATP binding galactokinas... |
DNA-templated transcription galactose metabolic process positive regulation of transcription from RNA polymerase II promoter by galactose regulation of transcription from RNA polymerase II promoter by galactose | nucleus; transcription repressor complex | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific identical protein binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II-specific DNA-binding transcription factor binding zinc ion bind... | Saccharomyces cerevisiae | 3D-structure Activator Carbohydrate metabolism DNA-binding Galactose metabolism Metal-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Zinc | MKLLSSIEQA | MKLLSSIEQACDICRLKKLKCSKEKPKCAKCLKNNWECRYSPKTKRSPLTRAHLTEVESRLERLEQLFLLIFPREDLDMILKMDSLQDIKALLTGLFVQDNVNKDAVTDRLASVETDMPLTLRQHRISATSSSEESSNKGQRQLTVSIDSAAHHDNSTIPLDFMPRDALHGFDWSEEDDMSDGLPFLKTDPNNNGFFGDGSLLCILRSIGFKPENYTNSNVNRLPTMITDRYTLASRSTTSRLLQSYLNNFHPYCPIVHSPTLMMLYNNQIEIASKDQWQILFNCILAIGAWCIEGESTDIDVFYYQNAKSHLTSKVFES... | DNA-templated transcription galactose metabolic process positive regulation of transcription from RNA polymerase II promoter by galactose regulation of transcription from RNA polymerase II promoter by galactose nucleus; transcription repressor complex DNA-binding transcription activator activity, RNA polymerase II-spec... |
galactose metabolic process negative regulation of phosphorylation negative regulation of transcription by RNA polymerase II positive regulation of transcription from RNA polymerase II promoter by galactose regulation of transcription from RNA polymerase II promoter by galactose | cytoplasm; nucleus; transcription regulator complex; transcription repressor complex | DNA binding identical protein binding kinase inhibitor activity nucleotide binding RNA polymerase II-specific DNA-binding transcription factor binding | Saccharomyces cerevisiae | 3D-structure Acetylation Carbohydrate metabolism Direct protein sequencing DNA-binding Galactose metabolism Reference proteome Repressor Transcription Transcription regulation | MDYNKRSSVS | MDYNKRSSVSTVPNAAPIRVGFVGLNAAKGWAIKTHYPAILQLSSQFQITALYSPKIETSIATIQRLKLSNATAFPTLESFASSSTIDMIVIAIQVASHYEVVMPLLEFSKNNPNLKYLFVEWALACSLDQAESIYKAAAERGVQTIISLQGRKSPYILRAKELISQGYIGDINSIEIAGNGGWYGYERPVKSPKYIYEIGNGVDLVTTTFGHTIDILQYMTSSYFSRINAMVFNNIPEQELIDERGNRLGQRVPKTVPDHLLFQGTLLNGNVPVSCSFKGGKPTKKFTKNLVIDIHGTKGDLKLEGDAGFAEISNLVLY... | galactose metabolic process negative regulation of phosphorylation negative regulation of transcription by RNA polymerase II positive regulation of transcription from RNA polymerase II promoter by galactose regulation of transcription from RNA polymerase II promoter by galactose cytoplasm; nucleus; transcription regula... |
Ras protein signal transduction | plasma membrane | G protein activity GDP binding GTP binding GTPase activity | Drosophila melanogaster | Cell membrane GTP-binding Hydrolase Lipoprotein Membrane Methylation Nucleotide-binding Palmitate Prenylation Reference proteome | MQMQTYKLVV | MQMQTYKLVVVGGGGVGKSAITIQFIQSYFVTDYDPTIEDSYTKQCNIDDVPAKLDILDTAGQEEFSAMREQYMRSGEGFLLVFALNDHSSFDEIPKFQRQILRVKDRDEFPMLMVGNKCDLKHQQQVSLEEAQNTSRNLMIPYIECSAKLRVNVDQAFHELVRIVRKFQIAERPFIEQDYKKKGKRKCCLM | Ras protein signal transduction plasma membrane G protein activity GDP binding GTP binding GTPase activity Drosophila melanogaster Cell membrane GTP-binding Hydrolase Lipoprotein Membrane Methylation Nucleotide-binding Palmitate Prenylation Reference proteome MQMQTYKLVV MQMQTYKLVVVGGGGVGKSAITIQFIQSYFVTDYDPTIEDSYTKQCNID... |
arginine biosynthetic process via ornithine citrulline biosynthetic process | cytoplasm | amino acid binding metal ion binding ornithine carbamoyltransferase activity | Escherichia coli | 3D-structure Allosteric enzyme Amino-acid biosynthesis Arginine biosynthesis Cytoplasm Direct protein sequencing Metal-binding Reference proteome Transferase Zinc | MSGFYHKHFL | MSGFYHKHFLKLLDFTPAELNSLLQLAAKLKADKKSGKEEAKLTGKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPSGSQIGHKESIKDTARVLGRMYDGIQYRGYGQEIVETLAEYASVPVWNGLTNEFHPTQLLADLLTMQEHLPGKAFNEMTLVYAGDARNNMGNSMLEAAALTGLDLRLVAPQACWPEAALVTECRALAQQNGGNITLTEDVAKGVEGADFIYTDVWVSMGEAKEKWAERIALLREYQVNSKMMQLTGNPEVKFLHCLPAFHDDQTTLGKKMAEEFGLHGGMEVTDEVFESAASIVFDQAENR... | arginine biosynthetic process via ornithine citrulline biosynthetic process cytoplasm amino acid binding metal ion binding ornithine carbamoyltransferase activity Escherichia coli 3D-structure Allosteric enzyme Amino-acid biosynthesis Arginine biosynthesis Cytoplasm Direct protein sequencing Metal-binding Reference pro... |
base-excision repair base-excision repair, AP site formation DNA damage response DNA dealkylation involved in DNA repair DNA repair | cytoplasm; protein-DNA complex | alkylated DNA binding alkylbase DNA N-glycosylase activity DNA-3-methyladenine glycosylase activity DNA-3-methylguanine glycosylase activity DNA-7-methyladenine glycosylase activity DNA-7-methylguanine glycosylase activity | Escherichia coli | 3D-structure Direct protein sequencing DNA damage DNA repair Hydrolase Reference proteome | MYTLNWQPPY | MYTLNWQPPYDWSWMLGFLAARAVSSVETVADSYYARSLAVGEYRGVVTAIPDIARHTLHINLSAGLEPVAAECLAKMSRLFDLQCNPQIVNGALGRLGAARPGLRLPGCVDAFEQGVRAILGQLVSVAMAAKLTARVAQLYGERLDDFPEYICFPTPQRLAAADPQALKALGMPLKRAEALIHLANAALEGTLPMTIPGDVEQAMKTLQTFPGIGRWTANYFALRGWQAKDVFLPDDYLIKQRFPGMTPAQIRRYAERWKPWRSYALLHIWYTEGWQPDEA | base-excision repair base-excision repair, AP site formation DNA damage response DNA dealkylation involved in DNA repair DNA repair cytoplasm; protein-DNA complex alkylated DNA binding alkylbase DNA N-glycosylase activity DNA-3-methyladenine glycosylase activity DNA-3-methylguanine glycosylase activity DNA-7-methyladen... |
galactose catabolic process via UDP-galactose | cytosol | aldose 1-epimerase activity carbohydrate binding UDP-glucose 4-epimerase activity | Saccharomyces cerevisiae | 3D-structure Carbohydrate metabolism Galactose metabolism Isomerase Multifunctional enzyme NAD Phosphoprotein Reference proteome | MTAQLQSEST | MTAQLQSESTSKIVLVTGGAGYIGSHTVVELIENGYDCVVADNLSNSTYDSVARLEVLTKHHIPFYEVDLCDRKGLEKVFKEYKIDSVIHFAGLKAVGESTQIPLRYYHNNILGTVVLLELMQQYNVSKFVFSSSATVYGDATRFPNMIPIPEECPLGPTNPYGHTKYAIENILNDLYNSDKKSWKFAILRYFNPIGAHPSGLIGEDPLGIPNNLLPYMAQVAVGRREKLYIFGDDYDSRDGTPIRDYIHVVDLAKGHIAALQYLEAYNENEGLCREWNLGSGKGSTVFEVYHAFCKASGIDLPYKVTGRRAGDVLNLTA... | galactose catabolic process via UDP-galactose cytosol aldose 1-epimerase activity carbohydrate binding UDP-glucose 4-epimerase activity Saccharomyces cerevisiae 3D-structure Carbohydrate metabolism Galactose metabolism Isomerase Multifunctional enzyme NAD Phosphoprotein Reference proteome MTAQLQSEST MTAQLQSESTSKIVLVTG... |
cytokine-mediated signaling pathway immune response interleukin-5-mediated signaling pathway positive regulation of B cell proliferation positive regulation of cell population proliferation positive regulation of DNA-binding transcription factor activity positive regulation of DNA-templated transcription positive regul... | extracellular region; extracellular space | cytokine activity growth factor activity interleukin-5 receptor binding | Mus musculus | 3D-structure Cytokine Disulfide bond Glycoprotein Growth factor Reference proteome Secreted Signal | MRRMLLHLSV | MRRMLLHLSVLTLSCVWATAMEIPMSTVVKETLTQLSAHRALLTSNETMRLPVPTHKNHQLCIGEIFQGLDILKNQTVRGGTVEMLFQNLSLIKKYIDRQKEKCGEERRRTRQFLDYLQEFLGVMSTEWAMEG | cytokine-mediated signaling pathway immune response interleukin-5-mediated signaling pathway positive regulation of B cell proliferation positive regulation of cell population proliferation positive regulation of DNA-binding transcription factor activity positive regulation of DNA-templated transcription positive regul... |
antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to type II interferon defense response to fungus glucose metabolic process glycolytic process killing by host of symbiont cells killing of cells of another organism microtubule cytoskeleton organization negative regulation of endo... | cytoplasm; cytosol; extracellular exosome; GAIT complex; intracellular membrane-bounded organelle; lipid droplet; membrane; microtubule cytoskeleton; nuclear membrane; nucleus; perinuclear region of cytoplasm; plasma membrane; ribonucleoprotein complex; vesicle | aspartic-type endopeptidase inhibitor activity disordered domain specific binding glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity identical protein binding microtubule binding NAD binding NADP binding peptidyl-cysteine S-nitrosylase activity | Homo sapiens | 3D-structure Acetylation ADP-ribosylation Alternative splicing Apoptosis Cytoplasm Cytoskeleton Direct protein sequencing Glycolysis Glycoprotein Immunity Innate immunity Isopeptide bond Membrane Methylation NAD Nucleus Oxidation Oxidoreductase Phosphoprotein Reference proteome S-nitrosylation Transferase Translation r... | MGKVKVGVNG | MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVKLISWYDNEFGY... | antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to type II interferon defense response to fungus glucose metabolic process glycolytic process killing by host of symbiont cells killing of cells of another organism microtubule cytoskeleton organization negative regulation of endo... |
angiogenesis apoptotic process cell adhesion intracellular signal transduction negative regulation of glial cell apoptotic process positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway positive regulation of angiogenesis positive regulation of cardiac muscle hypertrophy positi... | cytoplasm; cytosol; mitochondrial membrane; nucleus; perinuclear region of cytoplasm; photoreceptor disc membrane; plasma membrane | ATP binding diacylglycerol-dependent serine/threonine kinase activity PDZ domain binding protein serine kinase activity protein serine/threonine kinase activity scaffold protein binding zinc ion binding | Bos taurus | Acetylation Angiogenesis Apoptosis ATP-binding Calcium Cell adhesion Cell membrane Cytoplasm Kinase Membrane Metal-binding Mitochondrion Nucleotide-binding Nucleus Phosphoprotein Reference proteome Repeat Serine/threonine-protein kinase Transferase Zinc Zinc-finger | MADVFPAAEP | MADVFPAAEPAAPQDVANRFARKGALRQKNVHEVKNHRFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTDEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPRWDESFTFKLKPSDKDRRLSEEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNVELRQKFEKAKLGPAGNKVISP... | angiogenesis apoptotic process cell adhesion intracellular signal transduction negative regulation of glial cell apoptotic process positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway positive regulation of angiogenesis positive regulation of cardiac muscle hypertrophy positi... |
modulation by virus of host chromatin organization negative regulation of protein import into nucleus negative regulation of protein localization to nucleus perturbation by virus of host apoptosis phosphorylation suppression by virus of host NF-kappaB cascade suppression by virus of host viral-induced cytoplasmic patte... | host cell cytoplasm; host cell nucleus; viral tegument | ATP binding protein sequestering activity protein serine kinase activity protein serine/threonine kinase activity | Human herpesvirus 1 | ATP-binding Host cytoplasm Host nucleus Host-virus interaction Kinase Modulation of host cell apoptosis by virus Modulation of host chromatin by virus Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MACRKFCRVY | MACRKFCRVYGGQGRRKEEAVPPETKPSRVFPHGPFYTPAEDACLDSPPPETPKPSHTTPPSEAERLCHLQEILAQMYGNQDYPIEDDPSADAADDVDEDAPDDVAYPEEYAEELFLPGDATGPLIGANDHIPPPCGASPPGIRRRSRDEIGATGFTAEELDAMDREAARAISRGGKPPSTMAKLVTGMGFTIHGALTPGSEGCVFDSSHPDYPQRVIVKAGWYTSTSHEARLLRRLDHPAILPLLDLHVVSGVTCLVLPKYQADLYTYLSRRLNPLGRPQIAAVSRQLLSAVDYIHRQGIIHRDIKTENIFINTPEDIC... | modulation by virus of host chromatin organization negative regulation of protein import into nucleus negative regulation of protein localization to nucleus perturbation by virus of host apoptosis phosphorylation suppression by virus of host NF-kappaB cascade suppression by virus of host viral-induced cytoplasmic patte... |
ammonia assimilation cycle arginine biosynthetic process arginine biosynthetic process via ornithine arginine metabolic process locomotory behavior positive regulation of nitric oxide biosynthetic process post-embryonic development urea cycle | cytoplasm; cytosol; extracellular exosome | argininosuccinate lyase activity identical protein binding | Homo sapiens | 3D-structure Acetylation Alternative splicing Amino-acid biosynthesis Arginine biosynthesis Disease variant Lyase Reference proteome Urea cycle | MASESGKLWG | MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEMDQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTDLRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVALTRDSERLLEVRKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVAEFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPST... | ammonia assimilation cycle arginine biosynthetic process arginine biosynthetic process via ornithine arginine metabolic process locomotory behavior positive regulation of nitric oxide biosynthetic process post-embryonic development urea cycle cytoplasm; cytosol; extracellular exosome argininosuccinate lyase activity id... |
glutathione biosynthetic process protein homotetramerization | cytoplasm; cytosol | ATP binding glutathione synthase activity identical protein binding magnesium ion binding | Escherichia coli | 3D-structure ATP-binding Direct protein sequencing Glutathione biosynthesis Ligase Magnesium Manganese Metal-binding Nucleotide-binding Reference proteome | MIKLGIVMDP | MIKLGIVMDPIANINIKKDSSFAMLLEAQRRGYELHYMEMGDLYLINGEARAHTRTLNVKQNYEEWFSFVGEQDLPLADLDVILMRKDPPFDTEFIYATYILERAEEKGTLIVNKPQSLRDCNEKLFTAWFSDLTPETLVTRNKAQLKAFWEKHSDIILKPLDGMGGASIFRVKEGDPNLGVIAETLTEHGTRYCMAQNYLPAIKDGDKRVLVVDGEPVPYCLARIPQGGETRGNLAAGGRGEPRPLTESDWKIARQIGPTLKEKGLIFVGLDIIGDRLTEINVTSPTCIREIEAEFPVSITGMLMDAIEARLQQQ | glutathione biosynthetic process protein homotetramerization cytoplasm; cytosol ATP binding glutathione synthase activity identical protein binding magnesium ion binding Escherichia coli 3D-structure ATP-binding Direct protein sequencing Glutathione biosynthesis Ligase Magnesium Manganese Metal-binding Nucleotide-bindi... |
adaptive immune response antigen processing and presentation of exogenous peptide antigen via MHC class II peptide antigen assembly with MHC class II protein complex positive regulation of immune response positive regulation of T cell activation positive regulation of T cell proliferation positive regulation of type II... | cell surface; clathrin-coated endocytic vesicle membrane; endocytic vesicle membrane; ER to Golgi transport vesicle membrane; Golgi membrane; late endosome membrane; lumenal side of endoplasmic reticulum membrane; lysosomal membrane; membrane; MHC class II protein complex; plasma membrane; trans-Golgi network membrane;... | MHC class II protein complex binding peptide antigen binding | Homo sapiens | 3D-structure Adaptive immunity Cell membrane Disulfide bond Endoplasmic reticulum Endosome Glycoprotein Golgi apparatus Immunity Lysosome Membrane MHC II Reference proteome Signal Transmembrane Transmembrane helix | MMVLQVSAAP | MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQRFLERYIYNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTLQRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNGDWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLIICGVGIFMHRRSKKVQRGSA | adaptive immune response antigen processing and presentation of exogenous peptide antigen via MHC class II peptide antigen assembly with MHC class II protein complex positive regulation of immune response positive regulation of T cell activation positive regulation of T cell proliferation positive regulation of type II... |
carbon dioxide transport cellular oxidant detoxification hydrogen peroxide catabolic process negative regulation of transcription by RNA polymerase II oxygen transport | haptoglobin-hemoglobin complex; hemoglobin complex | heme binding hemoglobin alpha binding metal ion binding organic acid binding oxygen binding oxygen carrier activity protein-containing complex binding | Mus musculus | Heme Iron Metal-binding Oxygen transport Reference proteome Transport | MVHFTAEEKA | MVHFTAEEKAAITSIWDKVDLEKVGGETLGRLLIVYPWTQRFFDKFGNLSSALAIMGNPRIRAHGKKVLTSLGLGVKNMDNLKETFAHLSELHCDKLHVDPENFKLLGNMLVIVLSTHFAKEFTPEVQAAWQKLVIGVANALSHKYH | carbon dioxide transport cellular oxidant detoxification hydrogen peroxide catabolic process negative regulation of transcription by RNA polymerase II oxygen transport haptoglobin-hemoglobin complex; hemoglobin complex heme binding hemoglobin alpha binding metal ion binding organic acid binding oxygen binding oxygen ca... |
cytoplasmic translation ribosomal large subunit assembly | cytosol; cytosolic large ribosomal subunit; preribosome, large subunit precursor | RNA binding rRNA binding structural constituent of ribosome | Saccharomyces cerevisiae | 3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding rRNA-binding Ubl conjugation | MAPSAKATAA | MAPSAKATAAKKAVVKGTNGKKALKVRTSATFRLPKTLKLARAPKYASKAVPHYNRLDSYKVIEQPITSETAMKKVEDGNILVFQVSMKANKYQIKKAVKELYEVDVLKVNTLVRPNGTKKAYVRLTADYDALDIANRIGYI | cytoplasmic translation ribosomal large subunit assembly cytosol; cytosolic large ribosomal subunit; preribosome, large subunit precursor RNA binding rRNA binding structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Reference proteome Ribonucleopr... |
cellular response to organic substance locomotory behavior long-term memory metanephric collecting duct development metanephric connecting tubule development metanephric distal convoluted tubule development metanephric part of ureteric bud development regulation of long-term synaptic potentiation regulation of presynap... | cytosol; dendrite; dendritic spine; GABA-ergic synapse; glutamatergic synapse; hippocampal mossy fiber to CA3 synapse; neuronal cell body; nucleus; synapse; terminal bouton | calcium ion binding calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration vitamin D binding zinc ion binding | Bos taurus | Acetylation Calcium Direct protein sequencing Metal-binding Reference proteome Repeat Vitamin D | MAESHLQSSL | MAESHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGVKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNIPTYKKSIMALSDGGKLYRTDLALILSAGDN | cellular response to organic substance locomotory behavior long-term memory metanephric collecting duct development metanephric connecting tubule development metanephric distal convoluted tubule development metanephric part of ureteric bud development regulation of long-term synaptic potentiation regulation of presynap... |
modulation by virus of host process suppression by virus of host autophagy suppression by virus of host cell cycle arrest suppression by virus of host PKR signaling suppression by virus of host toll-like receptor signaling pathway suppression by virus of host type I interferon-mediated signaling pathway suppression by ... | host cell cytoplasm; host cell nucleolus; host cell nucleus | DNA binding endopeptidase activity molecular sequestering activity protein serine/threonine kinase inhibitor activity RNA binding | Human herpesvirus 1 | DNA-binding Host cytoplasm Host nucleus Host-virus interaction Inhibition of host autophagy by virus Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Inhibition of host MDA5 by virus Inhibition of host PKR by virus Inhibition of host RIG-I by virus Inhibition o... | MSQTQPPAPV | MSQTQPPAPVGPGDPDVYLKGVPSAGMHPRGVHAPRGHPRMISGPPQRGDNDQAAGQCGDSGLLRVGADTTISKPSEAVRPPTIPRTPRVPREPRVPRPPREPREPRVPRAPRDPRVPRDPRDPRQPRSPREPRSPREPRSPREPRTPRTPREPRTARGSV | modulation by virus of host process suppression by virus of host autophagy suppression by virus of host cell cycle arrest suppression by virus of host PKR signaling suppression by virus of host toll-like receptor signaling pathway suppression by virus of host type I interferon-mediated signaling pathway suppression by ... |
virus-mediated perturbation of host defense response | host cell endosome membrane; host cell Golgi membrane; host cell junction; membrane; viral envelope; virion membrane | identical protein binding | Human herpesvirus 1 | 3D-structure Disulfide bond Glycoprotein Host cell junction Host cell membrane Host endosome Host Golgi apparatus Host membrane Host-virus interaction Membrane Phosphoprotein Reference proteome Signal Sulfation Transmembrane Transmembrane helix Viral envelope protein Viral immunoevasion Virion | MDRGAVVGFL | MDRGAVVGFLLGVCVVSCLAGTPKTSWRRVSVGEDVSLLPAPGPTGRGPTQKLLWAVEPLDGCGPLHPSWVSLMPPKQVPETVVDAACMRAPVPLAMAYAPPAPSATGGLRTDFVWQERAAVVNRSLVIHGVRETDSGLYTLSVGDIKDPARQVASVVLVVQPAPVPTPPPTPADYDEDDNDEGEDESLAGTPASGTPRLPPPPAPPRSWPSAPEVSHVRGVTVRMETPEAILFSPGETFSTNVSIHAIAHDDQTYSMDVVWLRFDVPTSCAEMRIYESCLYHPQLPECLSPADAPCAASTWTSRLAVRSYAGCSRTNPP... | virus-mediated perturbation of host defense response host cell endosome membrane; host cell Golgi membrane; host cell junction; membrane; viral envelope; virion membrane identical protein binding Human herpesvirus 1 3D-structure Disulfide bond Glycoprotein Host cell junction Host cell membrane Host endosome Host Golg... |
DNA replication viral DNA genome replication viral DNA strand displacement replication | host cell nuclear matrix; host cell nucleus | DNA binding double-stranded DNA binding single-stranded DNA binding | Human adenovirus C serotype 5 | Covalent protein-DNA linkage DNA replication DNA-binding Host nucleus Phosphoprotein Viral DNA replication | MALSVNDCAR | MALSVNDCARLTGQSVPTMEHFLPLRNIWNRVRDFPRASTTAAGITWMSRYIYGYHRLMLEDLAPGAPATLRWPLYRQPPPHFLVGYQYLVRTCNDYVFDSRAYSRLRYTELSQPGHQTVNWSVMANCTYTINTGAYHRFVDMDDFQSTLTQVQQAILAERVVADLALLQPMRGFGVTRMGGRGRHLRPNSAAAAAIDARDAGQEEGEEEVPVERLMQDYYKDLRRCQNEAWGMADRLRIQQAGPKDMVLLSTIRRLKTAYFNYIISSTSARNNPDRRPLPPATVLSLPCDCDWLDAFLERFSDPVDADSLRSLGGGVPT... | DNA replication viral DNA genome replication viral DNA strand displacement replication host cell nuclear matrix; host cell nucleus DNA binding double-stranded DNA binding single-stranded DNA binding Human adenovirus C serotype 5 Covalent protein-DNA linkage DNA replication DNA-binding Host nucleus Phosphoprotein Viral... |
fusion of virus membrane with host plasma membrane | T=13 icosahedral viral capsid; viral envelope; viral intermediate capsid | host cell surface receptor binding metal ion binding structural molecule activity | Rotavirus A | 3D-structure Calcium Capsid protein Intermediate capsid protein Metal-binding Ubl conjugation Virion Zinc | MDVLYSLSKT | MDVLYSLSKTLKDARDKIVEGTLYSNVSDLIQQFNQMIITMNGNEFQTGGIGNLPIRNWNFDFGLLGTTLLNLDANYVETARNTIDYFVDFVDNVCMDEMVRESQRNGIAPQSDSLIKLSGIKFKRINFDNSSEYIENWNLQNRRQRTGFTFHKPNIFPYSASFTLNRSQPAHDNLMGTMWLNAGSEIQVAGFDYSCAINAPANTQQFEHIVQLRRVLTTATITLLPDAERFSFPRVITSADGATTWYFNPVILRPNNVEIEFLLNGQIINTYQARFGTIIARNFDTIRLSFQLMRPPNMTPAVAALFPNAQPFEHHATV... | fusion of virus membrane with host plasma membrane T=13 icosahedral viral capsid; viral envelope; viral intermediate capsid host cell surface receptor binding metal ion binding structural molecule activity Rotavirus A 3D-structure Calcium Capsid protein Intermediate capsid protein Metal-binding Ubl conjugation Virion ... |
induction by virus of host autophagy protein complex oligomerization virus-mediated pore formation in host cell membrane | extracellular region; host caveola; host cell rough endoplasmic reticulum membrane; membrane | metal ion binding monoatomic ion channel activity toxin activity | Rotavirus A ) | 3D-structure Activation of host autophagy by virus Calcium Direct protein sequencing Enterotoxin Glycoprotein Host endoplasmic reticulum Host membrane Host-virus interaction Ion channel Ion transport Membrane Metal-binding Reference proteome Secreted Signal-anchor Toxin Transmembrane Transmembrane helix Transport Viral... | MEKLTDLNYT | MEKLTDLNYTLSVITLMNNTLHTILEDPGMAYFPYIASVLTGLFALNKASIPTMKIALKTSKCSYKVVKYCIVTIFNTLLKLAGYKEQITTKDEIEKQMDRVVKEMRRQLEMIDKLTTREIEQVELLKRIYDKLTVQTTGEIDMTKEINQKNVRTLEEWESGKNPYEPREVTAAM | induction by virus of host autophagy protein complex oligomerization virus-mediated pore formation in host cell membrane extracellular region; host caveola; host cell rough endoplasmic reticulum membrane; membrane metal ion binding monoatomic ion channel activity toxin activity Rotavirus A )3D-structure Activation of... |
induction by virus of host NF-kappaB cascade regulation of viral transcription transcription antitermination viral transcription | host cell cytoplasm; host cell nucleus; virion component | metal ion binding RNA binding structural molecule activity | Human respiratory syncytial virus A | 3D-structure Activation of host NF-kappa-B by virus Host cytoplasm Host nucleus Host-virus interaction Metal-binding Phosphoprotein RNA-binding Transcription Transcription antitermination Transcription regulation Viral transcription Virion Zinc Zinc-finger | MSRRNPCKFE | MSRRNPCKFEIRGHCLNGKRCHFSHNYFEWPPHALLVRQNFMLNRILKSMDKSIDTLSEISGAAELDRTEEYALGVVGVLESYIGSINNITKQSACVAMSKLLTELNSDDIKKLRDNEELNSPKIRVYNTVISYIESNRKNNKQTIHLLKRLPADVLKKTIKNTLDIHKSITINNPKESTVSDTNDHAKNNDTT | induction by virus of host NF-kappaB cascade regulation of viral transcription transcription antitermination viral transcription host cell cytoplasm; host cell nucleus; virion component metal ion binding RNA binding structural molecule activity Human respiratory syncytial virus A 3D-structure Activation of host NF-kapp... |
chromosome condensation chromosome organization sperm DNA condensation spermatogenesis | cytosol; nucleoplasm; nucleosome | DNA binding | Homo sapiens | Chromosome Developmental protein Differentiation Direct protein sequencing Disulfide bond DNA condensation DNA-binding Nucleosome core Nucleus Phosphoprotein Reference proteome Spermatogenesis | MARYRCCRSQ | MARYRCCRSQSRSRYYRQRQRSRRRRRRSCQTRRRAMRCCRPRYRPRCRRH | chromosome condensation chromosome organization sperm DNA condensation spermatogenesis cytosol; nucleoplasm; nucleosome DNA binding Homo sapiens Chromosome Developmental protein Differentiation Direct protein sequencing Disulfide bond DNA condensation DNA-binding Nucleosome core Nucleus Phosphoprotein Reference proteom... |
chromosome condensation chromosome organization nucleus organization spermatid development spermatogenesis | male germ cell nucleus; nucleoplasm; nucleosome; nucleus | cadmium ion binding DNA binding zinc ion binding | Homo sapiens | Alternative splicing Chromosome Developmental protein Differentiation Direct protein sequencing DNA condensation DNA-binding Nucleosome core Nucleus Phosphoprotein Reference proteome Spermatogenesis | MVRYRVRSLS | MVRYRVRSLSERSHEVYRQQLHGQEQGHHGQEEQGLSPEHVEVYERTHGQSHYRRRHCSRRRLHRIHRRQHRSCRRRKRRSCRHRRRHRRGCRTRKRTCRRH | chromosome condensation chromosome organization nucleus organization spermatid development spermatogenesis male germ cell nucleus; nucleoplasm; nucleosome; nucleus cadmium ion binding DNA binding zinc ion binding Homo sapiens Alternative splicing Chromosome Developmental protein Differentiation Direct protein sequencin... |
adaptive thermogenesis cellular response to fatty acid cellular response to hormone stimulus cellular response to reactive oxygen species mitochondrial transmembrane transport proton transmembrane transport regulation of reactive oxygen species biosynthetic process response to nutrient levels response to temperature st... | mitochondrial inner membrane | cardiolipin binding long-chain fatty acid binding oxidative phosphorylation uncoupler activity purine ribonucleotide binding | Mesocricetus auratus | Direct protein sequencing Ion channel Ion transport Membrane Mitochondrion Mitochondrion inner membrane Oxidation Reference proteome Repeat Transmembrane Transmembrane helix Transport | MVNPTTSEVH | MVNPTTSEVHPTMGVKIFSAGVAACLADIITFPLDTAKVRLQIQGEGQISSTIRYKGVLGTITTLAKTEGLPKLYSGLPAGIQRQISFASLRIGLYDTVQEYFSSGKETPPTLGNRISAGLMTGGVAVFIGQPTEVVKVRLQAQSHLHGIKPRYTGTYNAYRIIATTESFSTLWKGTTPNLLRNVIINCVELVTYDLMKGALVNNQILADDVPCHLLSAFVAGFCTTFLASPADVVKTRFINSLPGQYPSVPSCAMTMLTKEGPTAFFKGFVPSFLRLASWNVIMFVCFEQLKKELSKSRQTVDCTT | adaptive thermogenesis cellular response to fatty acid cellular response to hormone stimulus cellular response to reactive oxygen species mitochondrial transmembrane transport proton transmembrane transport regulation of reactive oxygen species biosynthetic process response to nutrient levels response to temperature st... |
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane suppression by virus of host tetherin activity suppression by virus of host type I interferon-mediated signaling pathway virion attachment to host cell | host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane | structural molecule activity | Human immunodeficiency virus type 2 subtype A | AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Inhibition of h... | MMNQLLIAIL | MMNQLLIAILLASACLVYCTQYVTVFYGVPTWKNATIPLFCATRNRDTWGTIQCLPDNDDYQEITLNVTEAFDAWNNTVTEQAIEDVWHLFETSIKPCVKLTPLCVAMKCSSTESSTGNNTTSKSTSTTTTTPTDQEQEISEDTPCARADNCSGLGEEETINCQFNMTGLERDKKKQYNETWYSKDVVCETNNSTNQTQCYMNHCNTSVITESCDKHYWDAIRFRYCAPPGYALLRCNDTNYSGFAPNCSKVVASTCTRMMETQTSTWFGFNGTRAENRTYIYWHGRDNRTIISLNKYYNLSLHCKRPGNKTVKQIMLMS... | clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane suppression by virus of host tetherin activity suppression by virus of host type I interferon-mediated signaling pathway virion attachment to host cell host cell endosome membrane; host cell plasma membrane; membra... |
actin filament organization clathrin-dependent endocytosis of virus by host cell evasion of host immune response fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft pol... | host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane | structural molecule activity | Human immunodeficiency virus type 1 group M subtype B | 3D-structure AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Li... | MRVKEKYQHL | MRVKEKYQHLWRWGWRWGTMLLGMLMICSATEKLWVTVYYGVPVWKEATTTLFCASDAKAYDTEVHNVWATHACVPTDPNPQEVVLVNVTENFNMWKNDMVEQMHEDIISLWDQSLKPCVKLTPLCVSLKCTDLKNDTNTNSSSGRMIMEKGEIKNCSFNISTSIRGKVQKEYAFFYKLDIIPIDNDTTSYKLTSCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNNKTFNGTGPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEVVIRSVNFTDNAKTIIVQLNTSVEINCTRPNNNTRKRIRIQRGPGRAFVTI... | actin filament organization clathrin-dependent endocytosis of virus by host cell evasion of host immune response fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft pol... |
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral p... | host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane | structural molecule activity | Human immunodeficiency virus type 1 group M subtype B | AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Lipoprotein Mem... | MRVMEMRKNC | MRVMEMRKNCQHLWKWGTMLLGMLMICSAAEDLWVTVYYGVPVWKEATTTLFCASEAKAYKTEVHNVWAKHACVPTDPNPQEVLLENVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVTLNCTDANLNGTNVTSSSGGTMMENGEIKNCSFQVTTSRRDKTQKKYALFYKLDVVPIEKGNISPKNNTSNNTSYGNYTLIHCNSSVITQACPKVSFEPIPIHYCTPAGFAILKCNDKKFNGTGPCKNVSTVQCTHGIRPVVSTQLLLNGSLAEEEVVIRSENFTDNVKTIIVQLNASVQINCTRPNNNTRKSI... | clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral p... |
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral p... | host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane | structural molecule activity | Human immunodeficiency virus type 1 group M subtype D | 3D-structure AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Li... | MRAREIERNC | MRAREIERNCPNLWKWGIMLLGILMICSAADNLWVTVYYGVPVWKEATTTLFCASDAKSYKTEAHNIWATHACVPTDPNPQEIELENVTENFNMWRNNMVEQIHEDIISLWDQSLKPCVKLTPLCVTLNCTDESDEWMGNVTGKNVTEDIRMKNCSFNITTVVRDKTKQVHALFYRLDIVPIDNDNSTNSTNYRLINCNTSAITQACPKVSFEPIPIHYCAPAGFAILKCRDKRFNGTGPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEIIIRSENLTNNAKIIIVQLNESVAINCTRPYKNTRQSTPIGLGQALYTT... | clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral p... |
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral p... | host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane | structural molecule activity | Human immunodeficiency virus type 1 group M subtype D | AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Lipoprotein Mem... | MRARGIERNC | MRARGIERNCQNWWKWGIMLLGILMTCSAADNLWVTVYYGVPVWKEATTTLFCASDAKSYETEAHNIWATHACVPTDPNPQEIALENVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVTLNCSDELRNNGTMGNNVTTEEKGMKNCSFNVTTVLKDKKQQVYALFYRLDIVPIDNDSSTNSTNYRLINCNTSAITQACPKVSFEPIPIHYCAPAGFAILKCRDKKFNGTGPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEVIIRSENLTNNAKNIIAHLNESVKITCARPYQNTRQRTPIGLGQSLYTTR... | clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral p... |
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral p... | host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane | structural molecule activity | Human immunodeficiency virus type 1 group M subtype B | 3D-structure AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Li... | MRVKEKYQHL | MRVKEKYQHLWRWGWRWGTMLLGMLMICSATEKLWVTVYFGVPVWKEATTTLFCASDAKAYDTEVHNVWATHACVPTDPNPQEVVLVNVTENFNMWKNDMVEQMHEDIISLWDQSLKPCVKLTPLCVSLKCTDLKNDTNTNSSSGRMIMEKGEIKNCSFNISTSKRGKVQKEYAFFYKLDIIPIDNDTTSYTLTSCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNNKTFNGTGPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEVVIRSVNFTDNAKTIIVQLDTSVEINCTRPNNNTRKKIRIQRGPGRAFVTI... | clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral p... |
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral p... | host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane | structural molecule activity | Human immunodeficiency virus type 1 group M subtype A | 3D-structure AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Li... | MRVREIQRNY | MRVREIQRNYQNWWRWGMMLLGMLMTCSIAEDLWVTVYYGVPVWKEATTTLFCASDAKSYETEVHNIWATHACVPTDPNPQEIELENVTEGFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVTLNCTNVNGTAVNGTNAGSNRTNAELKMEIGEVKNCSFNITPVGSDKRQEYATFYNLDLVQIDDSDNSSYRLINCNTSVITQACPKVTFDPIPIHYCAPAGFAILKCNDKKFNGTEICKNVSTVQCTHGIKPVVSTQLLLNGSLAEEEIMIRSENLTDNTKNIIVQLNETVTINCTRPGNNTRRGIHFGPGQAL... | clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral p... |
viral budding via host ESCRT complex | host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane | RNA binding structural molecule activity zinc ion binding | Human immunodeficiency virus type 2 subtype A | 3D-structure AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Phosphoprotein Reference proteome Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucl... | MGARNSVLRG | MGARNSVLRGKKADELERIRLRPGGKKKYRLKHIVWAANKLDRFGLAESLLESKEGCQKILTVLDPMVPTGSENLKSLFNTVCVIWCIHAEEKVKDTEGAKQIVRRHLVAETGTAEKMPSTSRPTAPSSEKGGNYPVQHVGGNYTHIPLSPRTLNAWVKLVEEKKFGAEVVPGFQALSEGCTPYDINQMLNCVGDHQAAMQIIREIINEEAAEWDVQHPIPGPLPAGQLREPRGSDIAGTTSTVEEQIQWMFRPQNPVPVGNIYRRWIQIGLQKCVRMYNPTNILDIKQGPKEPFQSYVDRFYKSLRAEQTDPAVKNWMT... | viral budding via host ESCRT complex host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane RNA binding structural molecule activity zinc ion binding Human immunodeficiency virus type 2 subtype A 3D-structure AIDS Capsid protein Host cell membrane Host cyt... |
viral budding via host ESCRT complex | host cell nuclear membrane; host cell plasma membrane; host cellular component; host multivesicular body; membrane; viral nucleocapsid; virion membrane | RNA binding structural molecule activity zinc ion binding | Human immunodeficiency virus type 1 group M subtype B | 3D-structure AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Methylation Myristate Phosphoprotein Reference proteome Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexe... | MGARASVLSG | MGARASVLSGGELDRWEKIRLRPGGKKKYKLKHIVWASRELERFAVNPGLLETSEGCRQILGQLQPSLQTGSEELRSLYNTVATLYCVHQRIEIKDTKEALDKIEEEQNKSKKKAQQAAADTGHSNQVSQNYPIVQNIQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRVHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTNNPPIPVGEIYKRWIILGLNKIVRMYSPTSILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNWMTET... | viral budding via host ESCRT complex host cell nuclear membrane; host cell plasma membrane; host cellular component; host multivesicular body; membrane; viral nucleocapsid; virion membrane RNA binding structural molecule activity zinc ion binding Human immunodeficiency virus type 1 group M subtype B 3D-structure AIDS ... |
viral budding via host ESCRT complex | host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane | RNA binding structural molecule activity zinc ion binding | Human immunodeficiency virus type 1 group M subtype D | AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Methylation Myristate Phosphoprotein Reference proteome Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucle... | MGARASVLSG | MGARASVLSGGKLDKWEKIRLRPGGKKKYRLKHIVWASRELERYALNPGLLETSEGCKQIIGQLQPAIQTGTEELRSLYNTVATLYCVHKGIDVKDTKEALEKMEEEQNKSKKKAQQAAADTGNNSQVSQNYPIVQNLQGQMVHQAISPRTLNAWVKVIEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIAWMTSNPPIPVGEIYKRWIIVGLNKIVRMYSPVSILDIRQGPKEPFRDYVDRFYKTLRAEQASQDVKNWMTET... | viral budding via host ESCRT complex host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane RNA binding structural molecule activity zinc ion binding Human immunodeficiency virus type 1 group M subtype D AIDS Capsid protein Host cell membrane Host cytoplas... |
viral budding via host ESCRT complex | host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane | RNA binding structural molecule activity zinc ion binding | Human immunodeficiency virus type 1 group M subtype B | AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Methylation Myristate Phosphoprotein Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucleoprotein Viral rele... | MGARASVLSG | MGARASVLSGGELDRWEKIRLRPGGKKKYKLKHIVWASRELERFAVNPGLLETSEGCRQILGQLQPSLQTGSEELRSLYNTVATLYCVHQRIEIKDTKEALDKIEEEQNKSKKKAQQAAADTGHSSQVSQNYPIVQNIQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRVHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTNNPPIPVGEIYKRWIILGLNKIVRMYSPTSILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNWMTET... | viral budding via host ESCRT complex host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane RNA binding structural molecule activity zinc ion binding Human immunodeficiency virus type 1 group M subtype B AIDS Capsid protein Host cell membrane Host cytoplas... |
viral budding via host ESCRT complex | host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane | RNA binding structural molecule activity zinc ion binding | Human immunodeficiency virus type 1 group M subtype A | AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Methylation Myristate Phosphoprotein Reference proteome Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucle... | MGARASVLSG | MGARASVLSGGKLDAWEKIRLRPGGKKKYRLKHLVWASRELERFALNPGLLETGEGCQQIMEQLQSTLKTGSEEIKSLYNTVATLYCVHQRIDVKDTKEALDKIEEIQNKSRQKTQQAAAAQQAAAATKNSSSVSQNYPIVQNAQGQMIHQAISPRTLNAWVKVIEEKAFSPEVIPMFSALSEGATPQDLNMMLNIVGGHQAAMQMLKDTINEEAADWDRVHPVHAGPIPPGQMREPRGSDIAGTTSTLQEQIGWMTSNPPIPVGDIYKRWIILGLNKIVRMYSPVSILDIRQGPKEPFRDYVDRFFKTLRAEQATQEVK... | viral budding via host ESCRT complex host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane RNA binding structural molecule activity zinc ion binding Human immunodeficiency virus type 1 group M subtype A AIDS Capsid protein Host cell membrane Host cytoplas... |
suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy | extracellular region; host cell Golgi membrane; host cell plasma membrane; membrane; virion component | GTP binding SH3 domain binding | Human immunodeficiency virus type 1 group M subtype B | 3D-structure AIDS Apoptosis Early protein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host autophagy by virus Inhibition of host MHC class I molecule presentation by virus Inhibition of host MHC class II molecule present... | MGGKWSKSSV | MGGKWSKSSVIGWPTVRERMRRAEPAADRVGAASRDLEKHGAITSSNTAATNAACAWLEAQEEEEVGFPVTPQVPLRPMTYKAAVDLSHFLKEKGGLEGLIHSQRRQDILDLWIYHTQGYFPDWQNYTPGPGVRYPLTFGWCYKLVPVEPDKIEEANKGENTSLLHPVSLHGMDDPEREVLEWRFDSRLAFHHVARELHPEYFKNC | suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy extracellular region; host cell Golgi membrane; host cell plasma membrane; membr... |
suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy | extracellular region; host cell Golgi membrane; host cell plasma membrane; membrane; virion component | GTP binding SH3 domain binding | Human immunodeficiency virus type 1 group M subtype D | 3D-structure AIDS Apoptosis Early protein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host autophagy by virus Inhibition of host MHC class I molecule presentation by virus Inhibition of host MHC class II molecule present... | MGGRWSKSSI | MGGRWSKSSIVGWPAIRERIRRTDPRRTDPAADGVGAASRDLEKHGAITSSNTRDTNADCAWLEAQEESEEVGFPVRPQVPLRPMTYKLAVDLSHFLKEKGGLEGLIWSKKRQEILDLWVYNTQGIFPDWQNYTPGPGIRYPLTFGWCFELVPVDPREVEEATEGETNCLLHPVCQHGMEDTEREVLKWRFNSRLAFEHKAREMHPEFYKDC | suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy extracellular region; host cell Golgi membrane; host cell plasma membrane; membr... |
suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy | extracellular region; host cell Golgi membrane; host cell plasma membrane; membrane; virion component | GTP binding SH3 domain binding | Human immunodeficiency virus type 1 group M subtype A | 3D-structure AIDS Apoptosis Early protein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host autophagy by virus Inhibition of host MHC class I molecule presentation by virus Inhibition of host MHC class II molecule present... | MGGKWSKSSI | MGGKWSKSSIVGWPKIRERIRRTPPTETGVGAVSQDAVSQDLDKCGAAASSSPAANNASCEPPEEEEEVGFPVRPQVPLRPMTYKGAFDLSHFLKEKGGLDGLVWSPKRQEILDLWVYHTQGYFPDWQNYTPGPGIRFPLTFGWCFKLVPMSPEEVEEANEGENNCLLHPISQHGMEDAEREVLKWKFDSSLALRHRAREQHPEYYKDC | suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy extracellular region; host cell Golgi membrane; host cell plasma membrane; membr... |
suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy | extracellular region; host cell Golgi membrane; host cell plasma membrane; membrane; virion component | GTP binding SH3 domain binding | Human immunodeficiency virus type 1 group M subtype D | AIDS Apoptosis Early protein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host autophagy by virus Inhibition of host MHC class I molecule presentation by virus Inhibition of host MHC class II molecule presentation by viru... | MGGKWSKSSI | MGGKWSKSSIVGWPAIRERIRRTNPAADGVGAVSRDLEKHGAITSSNTASTNADCAWLEAQEESDEVGFPVRPQVPLRPMTYKEALDLSHFLKEKGGLEGLIWSKKRQEILDLWVYNTQGIFPDWQNYTPGPGIRYPLTFGWCYELVPVDPQEVEEDTEGETNSLLHPICQHGMEDPERQVLKWRFNSRLAFEHKAREMHPEFYKN | suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy extracellular region; host cell Golgi membrane; host cell plasma membrane; membr... |
DNA-templated transcription evasion of host immune response modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translatio... | extracellular region; host cell cytoplasm; host cell nucleolus; host cell nucleus | actinin binding cyclin binding metal ion binding molecular sequestering activity protein domain specific binding protein serine/threonine phosphatase inhibitor activity RNA-binding transcription regulator activity trans-activation response element binding | Human immunodeficiency virus type 1 group M subtype B | 3D-structure Acetylation Activator AIDS Alternative splicing Apoptosis Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Isopeptide bond Metal-binding Methylation Modulation of host chromatin by virus Modulation... | MEPVDPRLEP | MEPVDPRLEPWKHPGSQPKTACTNCYCKKCCFHCQVCFITKALGISYGRKKRRQRRRAHQNSQTHQASLSKQPTSQPRGDPTGPKE | DNA-templated transcription evasion of host immune response modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translatio... |
DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by viru... | extracellular region; host cell cytoplasm; host cell nucleolus | actinin binding cyclin binding metal ion binding protein domain specific binding protein serine/threonine phosphatase inhibitor activity RNA-binding transcription regulator activity trans-activation response element binding | Human immunodeficiency virus type 1 group M subtype D | Acetylation Activator AIDS Alternative splicing Apoptosis Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Isopeptide bond Metal-binding Methylation Modulation of host chromatin by virus Modulation of host PP1 ... | MDPVDPNLEP | MDPVDPNLEPWNHPGSQPKTACNRCHCKKCCYHCQVCFITKGLGISYGRKKRRQRRRPSQGGQTHQDPIPKQPSSQPRGNPTGPKE | DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by viru... |
DNA-templated transcription membrane hyperpolarization modulation by virus of host chromatin organization negative regulation of cellular respiration negative regulation of peptidyl-threonine phosphorylation positive regulation of NF-kappaB transcription factor activity positive regulation of protein localization to nu... | extracellular region; host cell cytoplasm; host cell nucleolus | actinin binding cyclin binding metal ion binding protein domain specific binding protein serine/threonine phosphatase inhibitor activity regulatory region RNA binding RNA-binding transcription regulator activity trans-activation response element binding | Human immunodeficiency virus type 1 group M subtype B | 3D-structure Acetylation Activator AIDS Alternative splicing Apoptosis Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Isopeptide bond Metal-binding Methylation Modulation of host chromatin by virus Modulation... | MEPVDPRLEP | MEPVDPRLEPWKHPGSQPKTACTTCYCKKCCFHCQVCFTTKALGISYGRKKRRQRRRPPQGSQTHQVSLSKQPTSQPRGDPTGPKE | DNA-templated transcription membrane hyperpolarization modulation by virus of host chromatin organization negative regulation of cellular respiration negative regulation of peptidyl-threonine phosphorylation positive regulation of NF-kappaB transcription factor activity positive regulation of protein localization to nu... |
DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by viru... | extracellular region; host cell cytoplasm; host cell nucleolus | actinin binding cyclin binding metal ion binding protein domain specific binding protein serine/threonine phosphatase inhibitor activity regulatory region RNA binding RNA-binding transcription regulator activity trans-activation response element binding | Human immunodeficiency virus type 1 group M subtype D | Acetylation Activator AIDS Alternative splicing Apoptosis Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Isopeptide bond Metal-binding Methylation Modulation of host chromatin by virus Modulation of host PP1 ... | MDPVDPNLEP | MDPVDPNLEPWNHPGSQPRTPCNKCHCKKCCYHCPVCFLNKGLGISYGRKKRRQRRGPPQGGQAHQVPIPKQPSSQPRGDPTGPKEQKKKVESEAETDP | DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by viru... |
DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by viru... | extracellular region; host cell cytoplasm; host cell nucleolus | actinin binding cyclin binding metal ion binding protein domain specific binding protein serine/threonine phosphatase inhibitor activity regulatory region RNA binding RNA-binding transcription regulator activity trans-activation response element binding | Human immunodeficiency virus type 1 group M subtype A | 3D-structure Acetylation Activator AIDS Alternative splicing Apoptosis Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Isopeptide bond Metal-binding Methylation Modulation of host chromatin by virus Modulation... | MDPVDPNLEP | MDPVDPNLEPWNHPGSQPRTPCNKCYCKKCCYHCQMCFITKGLGISYGRKKRRQRRRPPQGNQAHQDPLPEQPSSQHRGDHPTGPKE | DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by viru... |
DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by viru... | extracellular region; host cell cytoplasm; host cell nucleolus | actinin binding cyclin binding metal ion binding protein domain specific binding protein serine/threonine phosphatase inhibitor activity RNA-binding transcription regulator activity trans-activation response element binding | Human immunodeficiency virus type 1 group M subtype B | Acetylation Activator AIDS Alternative splicing Apoptosis Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Isopeptide bond Metal-binding Methylation Modulation of host chromatin by virus Modulation of host PP1 ... | MEPVDPNLEP | MEPVDPNLEPWKHPGSQPRTACNNCYCKKCCFHCYACFTRKGLGISYGRKKRRQRRRAPQDSQTHQASLSKQPASQSRGDPTGPTESKKKVERETETDPFD | DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by viru... |
mRNA transport protein export from nucleus viral process | host cell cytoplasm; host cell nucleolus | DNA-binding transcription factor activity RNA binding | Human immunodeficiency virus type 1 group M subtype B | 3D-structure AIDS Host cytoplasm Host nucleus Host-virus interaction Methylation mRNA transport Phosphoprotein Reference proteome RNA-binding Transport | MAGRSGDSDE | MAGRSGDSDEDLLKAVRLIKFLYQSNPPPNPEGTRQARRNRRRRWRERQRQIHSISERILSTYLGRSAEPVPLQLPPLERLTLDCNEDCGTSGTQGVGSPQILVESPTVLESGAKE | mRNA transport protein export from nucleus viral process host cell cytoplasm; host cell nucleolus DNA-binding transcription factor activity RNA binding Human immunodeficiency virus type 1 group M subtype B 3D-structure AIDS Host cytoplasm Host nucleus Host-virus interaction Methylation mRNA transport Phosphoprotein Re... |
mRNA transport viral process | host cell cytoplasm; host cell nucleolus | DNA-binding transcription factor activity identical protein binding RNA binding | Human immunodeficiency virus type 1 group M subtype B | 3D-structure AIDS Host cytoplasm Host nucleus Host-virus interaction Methylation mRNA transport Phosphoprotein Reference proteome RNA-binding Transport | MAGRSGDSDE | MAGRSGDSDEELIRTVRLIKLLYQSNPPPNPEGTRQARRNRRRRWRERQRQIHSISERILGTYLGRSAEPVPLQLPPLERLTLDCNEDCGTSGTQGVGSPQILVESPTVLESGTKE | mRNA transport viral process host cell cytoplasm; host cell nucleolus DNA-binding transcription factor activity identical protein binding RNA binding Human immunodeficiency virus type 1 group M subtype B 3D-structure AIDS Host cytoplasm Host nucleus Host-virus interaction Methylation mRNA transport Phosphoprotein Refe... |
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral p... | host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane | structural molecule activity | Human immunodeficiency virus type 1 group M subtype B | 3D-structure AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Li... | MRVKEKYQHL | MRVKEKYQHLWRWGWRWGTMLLGMLMICSATEKLWVTVYYGVPVWKEATTTLFCASDAKAYDTEVHNVWATHAGVPTDPNPQEVVLVNVTENFNMWKNDMVEQMHEDIISLWDQSLKPCVKLTPLCVSLKCTDLKNDTNTNSSSGRMIMEKGEIKNCSFNISTSIRGKVQKEYAFFYKLDIIPIDNDTTSYTLTSCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNNKTFNGTGPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEVVIRSVNFTDNAKTIIVQLNTSVEINCTRPNNNTRKKIRIQRGPGRAFVTI... | clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral p... |
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