Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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apoptotic signaling pathway cell recognition T cell costimulation | external side of plasma membrane; plasma membrane | signaling receptor activity | Homo sapiens | 3D-structure Cell membrane Disulfide bond Glycoprotein Membrane Phosphoprotein Reference proteome Repeat Signal Transmembrane Transmembrane helix | MPMGSLQPLA | MPMGSLQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSIICYGQLGSFSNCSHSRNDMCHSLGLTCLEPQKTTPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQ... | apoptotic signaling pathway cell recognition T cell costimulation external side of plasma membrane; plasma membrane signaling receptor activity Homo sapiens 3D-structure Cell membrane Disulfide bond Glycoprotein Membrane Phosphoprotein Reference proteome Repeat Signal Transmembrane Transmembrane helix MPMGSLQPLA MPMGSL... |
cobalamin transport monoatomic ion transmembrane transport | cell outer membrane; membrane; pore complex; transmembrane transporter complex | ABC-type vitamin B12 transporter activity calcium ion binding porin activity protein domain specific binding | Escherichia coli | 3D-structure Calcium Cell outer membrane Direct protein sequencing Ion transport Membrane Metal-binding Porin Receptor Reference proteome Signal TonB box Transmembrane Transmembrane beta strand Transport | MIKKASLLTA | MIKKASLLTACSVTAFSAWAQDTSPDTLVVTANRFEQPRSTVLAPTTVVTRQDIDRWQSTSVNDVLRRLPGVDITQNGGSGQLSSIFIRGTNASHVLVLIDGVRLNLAGVSGSADLSQFPIALVQRVEYIRGPRSAVYGSDAIGGVVNIITTRDEPGTEISAGWGSNSYQNYDVSTQQQLGDKTRVTLLGDYAHTHGYDVVAYGNTGTQAQTDNDGFLSKTLYGALEHNFTDAWSGFVRGYGYDNRTNYDAYYSPGSPLLDTRKLYSQSWDAGLRYNGELIKSQLITSYSHSKDYNYDPHYGRYDSSATLDEMKQYTVQW... | cobalamin transport monoatomic ion transmembrane transport cell outer membrane; membrane; pore complex; transmembrane transporter complex ABC-type vitamin B12 transporter activity calcium ion binding porin activity protein domain specific binding Escherichia coli 3D-structure Calcium Cell outer membrane Direct protein ... |
heme A biosynthetic process heme B biosynthetic process heme biosynthetic process heme O biosynthetic process porphyrin-containing compound catabolic process porphyrin-containing compound metabolic process protoporphyrinogen IX biosynthetic process | cytosol; nucleoplasm | uroporphyrinogen decarboxylase activity | Homo sapiens | 3D-structure Acetylation Cytoplasm Decarboxylase Direct protein sequencing Disease variant Heme biosynthesis Lyase Porphyrin biosynthesis Reference proteome | MEANGLGPQG | MEANGLGPQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCELTLQPLRRFPLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLIGFAGAPWTLMTYMVEGGGSSTMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMIIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIGQL... | heme A biosynthetic process heme B biosynthetic process heme biosynthetic process heme O biosynthetic process porphyrin-containing compound catabolic process porphyrin-containing compound metabolic process protoporphyrinogen IX biosynthetic process cytosol; nucleoplasm uroporphyrinogen decarboxylase activity Homo sapie... |
cellular glucuronidation estrogen metabolic process | endoplasmic reticulum membrane | glucuronosyltransferase activity | Homo sapiens | Alternative splicing Endoplasmic reticulum Glycoprotein Glycosyltransferase Lipid metabolism Membrane Reference proteome Signal Transferase Transmembrane Transmembrane helix | MSMKWTSALL | MSMKWTSALLLIQLSCYFSSGSCGKVLVWPTEFSHWMNIKTILDELVQRGHEVTVLASSASISFDPNSPSTLKFEVYPVSLTKTEFEDIIKQLVKRWAELPKDTFWSYFSQVQEIMWTFNDILRKFCKDIVSNKKLMKKLQESRFDVVLADAVFPFGELLAELLKIPFVYSLRFSPGYAIEKHSGGLLFPPSYVPVVMSELSDQMTFIERVKNMIYVLYFEFWFQIFDMKKWDQFYSEVLGRPTTLSETMAKADIWLIRNYWDFQFPHPLLPNVEFVGGLHCKPAKPLPKEMEEFVQSSGENGVVVFSLGSMVSNTSEER... | cellular glucuronidation estrogen metabolic process endoplasmic reticulum membrane glucuronosyltransferase activity Homo sapiens Alternative splicing Endoplasmic reticulum Glycoprotein Glycosyltransferase Lipid metabolism Membrane Reference proteome Signal Transferase Transmembrane Transmembrane helix MSMKWTSALL MSMKWT... |
cell division division septum assembly FtsZ-dependent cytokinesis | cell division site; divisome complex; FtsQBL complex; plasma membrane | identical protein binding | Escherichia coli | 3D-structure Cell cycle Cell division Cell inner membrane Cell membrane Membrane Reference proteome Transmembrane Transmembrane helix | MSQAALNTRN | MSQAALNTRNSEEEVSSRRNNGTRLAGILFLLTVLTTVLVSGWVVLGWMEDAQRLPLSKLVLTGERHYTRNDDIRQSILALGEPGTFMTQDVNIIQTQIEQRLPWIKQVSVRKQWPDELKIHLVEYVPIARWNDQHMVDAEGNTFSVPPERTSKQVLPMLYGPEGSANEVLQGYREMGQMLAKDRFTLKEAAMTARRSWQLTLNNDIKLNLGRGDTMKRLARFVELYPVLQQQAQTDGKRISYVDLRYDSGAAVGWAPLPPEESTQQQNQAQAEQQ | cell division division septum assembly FtsZ-dependent cytokinesis cell division site; divisome complex; FtsQBL complex; plasma membrane identical protein binding Escherichia coli 3D-structure Cell cycle Cell division Cell inner membrane Cell membrane Membrane Reference proteome Transmembrane Transmembrane helix MSQAALN... |
glycolytic process | cytoplasm | L-lactate dehydrogenase activity | Thermus caldophilus | 3D-structure Allosteric enzyme Cytoplasm Direct protein sequencing NAD Oxidoreductase Phosphoprotein | MKVGIVGSGM | MKVGIVGSGMVGSATAYALALLGVAREVVLVDLDRKLAQAHAEDILHATPFAHPVWVRAGSYGDLEGARAVVLAAGVAQRPGETRLQLLDRNAQVFAQVVPRVLEAAPEAVLLVATNPVDVMTQVAYRLSALPPGRVVGSGTILDTARFRALLAEHLRVAPQSVHAYVLGEHGDSEVLVWSSAQVGGVPLLEFAEARGRALSPEDRARIDEGVRRAAYRIIEGKGATYYGIGAGLARLVRAILTDEKGVYTVSAFTPEVEGVLEVSLSLPRILGAGGVEGTVYPSLSPEEREALRRSAEILKEAAFALGF | glycolytic process cytoplasm L-lactate dehydrogenase activity Thermus caldophilus3D-structure Allosteric enzyme Cytoplasm Direct protein sequencing NAD Oxidoreductase Phosphoprotein MKVGIVGSGM MKVGIVGSGMVGSATAYALALLGVAREVVLVDLDRKLAQAHAEDILHATPFAHPVWVRAGSYGDLEGARAVVLAAGVAQRPGETRLQLLDRNAQVFAQVVPRVLEAAPEAVLLVATNPVDVMTQVAY... |
cellular response to extracellular stimulus glucose catabolic process to lactate via pyruvate lactate biosynthetic process from pyruvate lactate metabolic process liver development NAD metabolic process positive regulation of apoptotic process pyruvate catabolic process pyruvate metabolic process skeletal muscle tissue... | cytosol; mitochondrion; oxidoreductase complex; sperm fibrous sheath | identical protein binding kinase binding L-lactate dehydrogenase activity lactate dehydrogenase activity NAD binding | Mus musculus | Acetylation Cytoplasm Direct protein sequencing Isopeptide bond NAD Oxidoreductase Phosphoprotein Reference proteome Ubl conjugation | MATLKDQLIV | MATLKDQLIVNLLKEEQAPQNKITVVGVGAVGMACAISILMKDLADELALVDVMEDKLKGEMMDLQHGSLFLKTPKIVSSKDYCVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNIVKYSPHCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHALSCHGWVLGEHGDSSVPVWSGVNVAGVSLKSLNPELGTDADKEQWKEVHKQVVDSAYEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPISTMIKGLYGINEDVFLSVPCILGQNGISDVVKVTLTPEEEARLKKSA... | cellular response to extracellular stimulus glucose catabolic process to lactate via pyruvate lactate biosynthetic process from pyruvate lactate metabolic process liver development NAD metabolic process positive regulation of apoptotic process pyruvate catabolic process pyruvate metabolic process skeletal muscle tissue... |
branched-chain amino acid biosynthetic process isoleucine biosynthetic process mitochondrial genome maintenance valine biosynthetic process | mitochondrial nucleoid; mitochondrion | double-stranded DNA binding ketol-acid reductoisomerase activity metal ion binding | Saccharomyces cerevisiae | Amino-acid biosynthesis Branched-chain amino acid biosynthesis Direct protein sequencing Magnesium Metal-binding Mitochondrion NADP Oxidoreductase Phosphoprotein Reference proteome Transit peptide | MLRTQAARLI | MLRTQAARLICNSRVITAKRTFALATRAAAYSRPAARFVKPMITTRGLKQINFGGTVETVYERADWPREKLLDYFKNDTFALIGYGSQGYGQGLNLRDNGLNVIIGVRKDGASWKAAIEDGWVPGKNLFTVEDAIKRGSYVMNLLSDAAQSETWPAIKPLLTKGKTLYFSHGFSPVFKDLTHVEPPKDLDVILVAPKGSGRTVRSLFKEGRGINSSYAVWNDVTGKAHEKAQALAVAIGSGYVYQTTFEREVNSDLYGERGCLMGGIHGMFLAQYDVLRENGHSPSEAFNETVEEATQSLYPLIGKYGMDYMYDACSTTA... | branched-chain amino acid biosynthetic process isoleucine biosynthetic process mitochondrial genome maintenance valine biosynthetic process mitochondrial nucleoid; mitochondrion double-stranded DNA binding ketol-acid reductoisomerase activity metal ion binding Saccharomyces cerevisiae Amino-acid biosynthesis Branched-... |
aromatic amino acid family catabolic process to alcohol via Ehrlich pathway branched-chain amino acid catabolic process glycolytic fermentation to ethanol L-phenylalanine catabolic process pyruvate metabolic process tryptophan catabolic process | cytoplasm; cytosol; nucleus | branched-chain-2-oxoacid decarboxylase activity indolepyruvate decarboxylase activity magnesium ion binding phenylpyruvate decarboxylase activity pyruvate decarboxylase activity thiamine pyrophosphate binding | Saccharomyces cerevisiae | 3D-structure Acetylation Allosteric enzyme Branched-chain amino acid catabolism Cytoplasm Decarboxylase Direct protein sequencing Isopeptide bond Lyase Magnesium Metal-binding Methylation Nucleus Phenylalanine catabolism Phosphoprotein Reference proteome Thiamine pyrophosphate Tryptophan catabolism Ubl conjugation | MSEITLGKYL | MSEITLGKYLFERLKQVNVNTVFGLPGDFNLSLLDKIYEVEGMRWAGNANELNAAYAADGYARIKGMSCIITTFGVGELSALNGIAGSYAEHVGVLHVVGVPSISAQAKQLLLHHTLGNGDFTVFHRMSANISETTAMITDIATAPAEIDRCIRTTYVTQRPVYLGLPANLVDLNVPAKLLQTPIDMSLKPNDAESEKEVIDTILALVKDAKNPVILADACCSRHDVKAETKKLIDLTQFPAFVTPMGKGSIDEQHPRYGGVYVGTLSKPEVKEAVESADLILSVGALLSDFNTGSFSYSYKTKNIVEFHSDHMKIRNAT... | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway branched-chain amino acid catabolic process glycolytic fermentation to ethanol L-phenylalanine catabolic process pyruvate metabolic process tryptophan catabolic process cytoplasm; cytosol; nucleus branched-chain-2-oxoacid decarboxylase activity... |
glandular epithelial cell maturation lung alveolus development negative regulation of gene expression ovulation from ovarian follicle paracrine signaling progesterone receptor signaling pathway regulation of epithelial cell proliferation tertiary branching involved in mammary gland duct morphogenesis | cytoplasm; nucleus; plasma membrane | ATPase binding DNA-binding transcription activator activity, RNA polymerase II-specific identical protein binding nuclear receptor activity nuclear steroid receptor activity RNA polymerase II cis-regulatory region sequence-specific DNA binding steroid binding transcription coactivator binding zinc ion binding | Oryctolagus cuniculus | Cytoplasm DNA-binding Isopeptide bond Lipid-binding Lipoprotein Metal-binding Nucleus Palmitate Phosphoprotein Receptor Reference proteome Steroid-binding Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | MTELKAKEPR | MTELKAKEPRAPHVAGGAPSPTEVGSQLLGRPDPGPFQGSQTSEASSVVSAIPISLDGLLFPRPCQGQNPPDGKTQDPPSLSDVEGAFPGVEAPEGAGDSSSRPPEKDSGLLDSVLDTLLAPSGPGQSHASPATCEAISPWCLFGPDLPEDPRAAPATKGVLAPLMSRPEDKAGDSSGTAAAHKVLPRGLSPSRQLLLPSSGSPHWPAVKPSPQPAAVQVDEEDSSESEGTVGPLLKGQPRALGGTAAGGGAAPVASGAAAGGVALVPKEDSRFSAPRVSLAEQDAPVAPGRSPLATSVVDFIHVPILPLNHAFLATRTR... | glandular epithelial cell maturation lung alveolus development negative regulation of gene expression ovulation from ovarian follicle paracrine signaling progesterone receptor signaling pathway regulation of epithelial cell proliferation tertiary branching involved in mammary gland duct morphogenesis cytoplasm; nucleus... |
phosphatidylinositol biosynthetic process | endoplasmic reticulum; endoplasmic reticulum membrane; Golgi apparatus; membrane; mitochondrial outer membrane; mitochondrion | CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity metal ion binding | Saccharomyces cerevisiae | Endoplasmic reticulum Lipid biosynthesis Lipid metabolism Magnesium Manganese Membrane Metal-binding Mitochondrion Mitochondrion outer membrane Phospholipid biosynthesis Phospholipid metabolism Reference proteome Transferase Transmembrane Transmembrane helix | MSSNSTPEKV | MSSNSTPEKVTAEHVLWYIPNKIGYVRVITAALSFFVMKNHPTAFTWLYSTSCLLDALDGTMARKYNQVSSLGAVLDMVTDRSSTAGLMCFLCVQYPQWCVFFQLMLGLDITSHYMHMYASLSAGKTSHKSVGEGESRLLHLYYTRRDVLFTICAFNELFYAGLYLQLFSNSATFGKWTTIISFPGYVFKQTANVVQLKRAALILADNDAKNANEKNKTY | phosphatidylinositol biosynthetic process endoplasmic reticulum; endoplasmic reticulum membrane; Golgi apparatus; membrane; mitochondrial outer membrane; mitochondrion CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity metal ion binding Saccharomyces cerevisiae Endoplasmic reticulum Lipid biosynthesis Lipi... |
adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway chemical synaptic transmission G protein-coupled acetylcholine receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger regulation of heart contraction regulation of smoo... | dendrite; plasma membrane; postsynaptic membrane; synapse | G protein-coupled acetylcholine receptor activity G protein-coupled serotonin receptor activity | Sus scrofa | Cell membrane Direct protein sequencing Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Postsynaptic cell membrane Receptor Reference proteome Synapse Transducer Transmembrane Transmembrane helix | MNNSTNSSNS | MNNSTNSSNSGLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQEPVSPSLVQGRIVKPNNNNMPGSDEALEHNKIQNGKAPRDAVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLGHSKDENS... | adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway chemical synaptic transmission G protein-coupled acetylcholine receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger regulation of heart contraction regulation of smoo... |
leucine biosynthetic process | cytoplasm; mitochondrion | 2-isopropylmalate synthase activity metal ion binding | Saccharomyces cerevisiae | Alternative initiation Amino-acid biosynthesis Branched-chain amino acid biosynthesis Cytoplasm Leucine biosynthesis Metal-binding Mitochondrion Reference proteome Transferase | MVKESIIALA | MVKESIIALAEHAASRASRVIPPVKLAYKNMLKDPSSKYKPFNAPKLSNRKWPDNRITRAPRWLSTDLRDGNQSLPDPMSVEQKKEYFHKLVNIGFKEIEVSFPSASQTDFDFTRYAVENAPDDVSIQCLVQSREHLIKRTVEALTGAKKATIHTYLATSDMFREIVFNMSREEAISKAVEATKLVRKLTKDDPSQQATRWSYEFSPECFSDTPGEFAVEICEAVKKAWEPTEENPIIFNLPATVEVASPNVYADQIEYFATHITEREKVCISTHCHNDRGCGVAATELGMLAGADRVEGCLFGNGERTGNVDLVTVAMN... | leucine biosynthetic process cytoplasm; mitochondrion 2-isopropylmalate synthase activity metal ion binding Saccharomyces cerevisiae Alternative initiation Amino-acid biosynthesis Branched-chain amino acid biosynthesis Cytoplasm Leucine biosynthesis Metal-binding Mitochondrion Reference proteome Transferase MVKESIIALA... |
cellular response to estrogen stimulus intracellular estrogen receptor signaling pathway positive regulation of gene expression regulation of transcription by RNA polymerase II | cytoplasm; nucleus | estrogen response element binding Hsp90 protein binding nuclear estrogen receptor activity nuclear receptor activity steroid binding zinc ion binding | Gallus gallus | DNA-binding Lipid-binding Metal-binding Nucleus Receptor Reference proteome Steroid-binding Transcription Transcription regulation Zinc Zinc-finger | MTMTLHTKAS | MTMTLHTKASGVTLLHQIQGTELETLSRPQLKIPLERSLSDMYVESNKTGVFNYPEGATYDFGTTAPVYGSTTLSYAPTSESFGSSSLAGFHSLNNVPPSPVVFLQTAPQLSPFIHHHSQQVPYYLENEQGSFGMREAAPPAFYRPSSDNRRHSIRERMSSTNEKGSLSMESTKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGEMMKQKRQREEQDSRNGEASSTELRAPTLWTSPLVVKHNKKNSPALSLTAEQMVSALLEAEPPI... | cellular response to estrogen stimulus intracellular estrogen receptor signaling pathway positive regulation of gene expression regulation of transcription by RNA polymerase II cytoplasm; nucleus estrogen response element binding Hsp90 protein binding nuclear estrogen receptor activity nuclear receptor activity steroid... |
DNA replication, Okazaki fragment processing late viral transcription viral DNA genome replication | viral replication complex | 5'-3' DNA exonuclease activity 5'-3' exonuclease activity 5'-flap endonuclease activity DNA binding DNA exonuclease activity double-stranded DNA endonuclease activity metal ion binding | Escherichia phage T5 | 3D-structure Direct protein sequencing DNA replication DNA-binding Early protein Endonuclease Exonuclease Hydrolase Magnesium Metal-binding Nuclease Potassium Reference proteome Viral DNA replication | MSKSWGKFIE | MSKSWGKFIEEEEAEMASRRNLMIVDGTNLGFRFKHNNSKKPFASSYVSTIQSLAKSYSARTTIVLGDKGKSVFRLEHLPEYKGNRDEKYAQRTEEEKALDEQFFEYLKDAFELCKTTFPTFTIRGVEADDMAAYIVKLIGHLYDHVWLISTDGDWDTLLTDKVSRFSFTTRREYHLRDMYEHHNVDDVEQFISLKAIMGDLGDNIRGVEGIGAKRGYNIIREFGNVLDIIDQLPLPGKQKYIQNLNASEELLFRNLILVDLPTYCVDAIAAVGQDVLDKFTKDILEIAEQ | DNA replication, Okazaki fragment processing late viral transcription viral DNA genome replication viral replication complex 5'-3' DNA exonuclease activity 5'-3' exonuclease activity 5'-flap endonuclease activity DNA binding DNA exonuclease activity double-stranded DNA endonuclease activity metal ion binding Escherichi... |
activation of cysteine-type endopeptidase activity involved in apoptotic process B cell receptor signaling pathway Fc-gamma receptor signaling pathway hemopoiesis innate immune response intracellular signal transduction intracellular zinc ion homeostasis leukocyte migration peptidyl-tyrosine autophosphorylation peptidy... | cytosol; extracellular exosome; extrinsic component of cytoplasmic side of plasma membrane; immunological synapse; membrane raft; pericentriolar material; plasma membrane | ATP binding ATPase binding CD4 receptor binding CD8 receptor binding identical protein binding non-membrane spanning protein tyrosine kinase activity phosphatidylinositol 3-kinase binding phospholipase activator activity phospholipase binding phosphotyrosine residue binding protein kinase binding protein phosphatase bi... | Homo sapiens | 3D-structure Alternative splicing ATP-binding Cell membrane Chromosomal rearrangement Cytoplasm Disease variant Host-virus interaction Kinase Lipoprotein Membrane Myristate Nucleotide-binding Palmitate Phosphoprotein Proto-oncogene Reference proteome SH2 domain SH3 domain Transferase Tyrosine-protein kinase | MGCGCSSHPE | MGCGCSSHPEDDWMENIDVCENCHYPIVPLDGKGTLLIRNGSEVRDPLVTYEGSNPPASPLQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPCQTQKPQKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEYME... | activation of cysteine-type endopeptidase activity involved in apoptotic process B cell receptor signaling pathway Fc-gamma receptor signaling pathway hemopoiesis innate immune response intracellular signal transduction intracellular zinc ion homeostasis leukocyte migration peptidyl-tyrosine autophosphorylation peptidy... |
7-methylguanosine mRNA capping cell cycle cell division cellular response to nitrogen starvation nucleotide-excision repair positive regulation of Atg1/ULK1 kinase complex assembly positive regulation of autophagy positive regulation of transcription by RNA polymerase II positive regulation of transcription elongation ... | cytoplasm; cytosol; nucleus; transcription factor TFIIH holo complex; transcription factor TFIIK complex | ATP binding cyclin-dependent protein serine/threonine kinase activity protein kinase activity RNA polymerase II CTD heptapeptide repeat kinase activity | Saccharomyces cerevisiae | 3D-structure ATP-binding Cell cycle Cell division Kinase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transcription Transcription regulation Transferase | MKVNMEYTKE | MKVNMEYTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQHPNVIELIDIFMAYDNLNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQIKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLRIPYLPGQNDVDQMEVTFRALGTPTDRDWPEVSSFMTYNKLQIYPPPSRDELRKRFIAASEYALDFMCGMLTMNPQKRWTAVQCLESDYFKELPPPSDPSSIKIRN | 7-methylguanosine mRNA capping cell cycle cell division cellular response to nitrogen starvation nucleotide-excision repair positive regulation of Atg1/ULK1 kinase complex assembly positive regulation of autophagy positive regulation of transcription by RNA polymerase II positive regulation of transcription elongation ... |
cell division DNA replication initiation double-strand break repair via break-induced replication mitotic DNA replication checkpoint signaling mitotic DNA replication preinitiation complex assembly negative regulation of exit from mitosis phosphorylation positive regulation of kinetochore assembly positive regulation o... | centrosome; chromatin; chromosome, centromeric region; Dbf4-dependent protein kinase complex; nucleus | ATP binding identical protein binding metal ion binding protein serine kinase activity protein serine/threonine kinase activity | Saccharomyces cerevisiae | 3D-structure ATP-binding Cell cycle Cell division Kinase Magnesium Meiosis Metal-binding Mitosis Nucleotide-binding Reference proteome Serine/threonine-protein kinase Transferase | MTSKTKNIDD | MTSKTKNIDDIPPEIKEEMIQLYHDLPGIENEYKLIDKIGEGTFSSVYKAKDITGKITKKFASHFWNYGSNYVALKKIYVTSSPQRIYNELNLLYIMTGSSRVAPLCDAKRVRDQVIAVLPYYPHEEFRTFYRDLPIKGIKKYIWELLRALKFVHSKGIIHRDIKPTNFLFNLELGRGVLVDFGLAEAQMDYKSMISSQNDYDNYANTNHDGGYSMRNHEQFCPCIMRNQYSPNSHNQTPPMVTIQNGKVVHLNNVNGVDLTKGYPKNETRRIKRANRAGTRGFRAPEVLMKCGAQSTKIDIWSVGVILLSLLGRRFPMF... | cell division DNA replication initiation double-strand break repair via break-induced replication mitotic DNA replication checkpoint signaling mitotic DNA replication preinitiation complex assembly negative regulation of exit from mitosis phosphorylation positive regulation of kinetochore assembly positive regulation o... |
cell cycle cell division negative regulation of cytoplasmic mRNA processing body assembly phosphorylation protein kinase A signaling Ras protein signal transduction regulation of macroautophagy | cAMP-dependent protein kinase complex; chromatin; cytoplasm; cytosol; nucleus | AMP-activated protein kinase activity ATP binding cAMP-dependent protein kinase activity protein kinase activity protein serine kinase activity | Saccharomyces cerevisiae | 3D-structure Acetylation ATP-binding cAMP Cell cycle Cell division Cytoplasm Kinase Nucleotide-binding Nucleus Reference proteome Serine/threonine-protein kinase Transferase | MSTEEQNGGG | MSTEEQNGGGQKSLDDRQGEESQKGETSERETTATESGNESKSVEKEGGETQEKPKQPHVTYYNEEQYKQFIAQARVTSGKYSLQDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNEDVKDLLSRLITRD... | cell cycle cell division negative regulation of cytoplasmic mRNA processing body assembly phosphorylation protein kinase A signaling Ras protein signal transduction regulation of macroautophagy cAMP-dependent protein kinase complex; chromatin; cytoplasm; cytosol; nucleus AMP-activated protein kinase activity ATP bindin... |
invasive growth in response to glucose limitation negative regulation of cytoplasmic mRNA processing body assembly negative regulation of cytoplasmic translation phosphorylation protein kinase A signaling Ras protein signal transduction | cAMP-dependent protein kinase complex; chromatin; cytosol; nucleus; P-body | AMP-activated protein kinase activity ATP binding cAMP-dependent protein kinase activity protein kinase activity protein serine kinase activity | Saccharomyces cerevisiae | Acetylation ATP-binding cAMP Kinase Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MEFVAERAQP | MEFVAERAQPVGQTIQQQNVNTYGQGVLQPHHDLQQRQQQQQQRQHQQLLTSQLPQKSLVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSKLITADLTRRIGNLQSGSRDIKA... | invasive growth in response to glucose limitation negative regulation of cytoplasmic mRNA processing body assembly negative regulation of cytoplasmic translation phosphorylation protein kinase A signaling Ras protein signal transduction cAMP-dependent protein kinase complex; chromatin; cytosol; nucleus; P-body AMP-acti... |
acetylcholine catabolic process choline metabolic process cocaine metabolic process learning negative regulation of cell population proliferation negative regulation of synaptic transmission neuroblast differentiation peptide hormone processing response to alkaloid response to folic acid response to glucocorticoid xeno... | blood microparticle; endoplasmic reticulum lumen; extracellular region; extracellular space; nuclear envelope lumen; plasma membrane | acetylcholinesterase activity amyloid-beta binding catalytic activity choline binding cholinesterase activity enzyme binding hydrolase activity, acting on ester bonds identical protein binding | Homo sapiens | 3D-structure Direct protein sequencing Disease variant Disulfide bond Glycoprotein Hydrolase Phosphoprotein Reference proteome Secreted Serine esterase Sialic acid Signal | MHSKVTIICI | MHSKVTIICIRFLFWFLLLCMLIGKSHTEDDIIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGP... | acetylcholine catabolic process choline metabolic process cocaine metabolic process learning negative regulation of cell population proliferation negative regulation of synaptic transmission neuroblast differentiation peptide hormone processing response to alkaloid response to folic acid response to glucocorticoid xeno... |
carbohydrate metabolic process | extracellular region | alpha-amylase activity calcium ion binding | Bacillus licheniformis | 3D-structure Calcium Carbohydrate metabolism Direct protein sequencing Glycosidase Hydrolase Metal-binding Secreted Signal | MKQQKRLYAR | MKQQKRLYARLLTLLFALIFLLPHSAAAAANLNGTLMQYFEWYMPNDGQHWKRLQNDSAYLAEHGITAVWIPPAYKGTSQADVGYGAYDLYDLGEFHQKGTVRTKYGTKGELQSAIKSLHSRDINVYGDVVINHKGGADATEDVTAVEVDPADRNRVISGEHRIKAWTHFHFPGRGSTYSDFKWHWYHFDGTDWDESRKLNRIYKFQGKAWDWEVSNENGNYDYLMYADIDYDHPDVAAEIKRWGTWYANELQLDGFRLDAVKHIKFSFLRDWVNHVREKTGKEMFTVAEYWQNDLGALENYLNKTNFNHSVFDVPLHYQ... | carbohydrate metabolic process extracellular region alpha-amylase activity calcium ion binding Bacillus licheniformis3D-structure Calcium Carbohydrate metabolism Direct protein sequencing Glycosidase Hydrolase Metal-binding Secreted Signal MKQQKRLYAR MKQQKRLYARLLTLLFALIFLLPHSAAAAANLNGTLMQYFEWYMPNDGQHWKRLQNDSAYLAEHGITAV... |
glycoside catabolic process glycosphingolipid catabolic process glycosylceramide catabolic process negative regulation of nitric oxide biosynthetic process negative regulation of nitric-oxide synthase activity oligosaccharide metabolic process | azurophil granule lumen; cytoplasm; extracellular exosome; extracellular region; Golgi apparatus; lysosomal lumen; lysosome | alpha-galactosidase activity catalytic activity galactoside binding hydrolase activity protein homodimerization activity signaling receptor binding | Homo sapiens | 3D-structure Direct protein sequencing Disease variant Disulfide bond Glycoprotein Glycosidase Hydrolase Lipid metabolism Lysosome Pharmaceutical Reference proteome RNA editing Signal | MQLRNPELHL | MQLRNPELHLGCALALRFLALVSWDIPGARALDNGLARTPTMGWLHWERFMCNLDCQEEPDSCISEKLFMEMAELMVSEGWKDAGYEYLCIDDCWMAPQRDSEGRLQADPQRFPHGIRQLANYVHSKGLKLGIYADVGNKTCAGFPGSFGYYDIDAQTFADWGVDLLKFDGCYCDSLENLADGYKHMSLALNRTGRSIVYSCEWPLYMWPFQKPNYTEIRQYCNHWRNFADIDDSWKSIKSILDWTSFNQERIVDVAGPGGWNDPDMLVIGNFGLSWNQQVTQMALWAIMAAPLFMSNDLRHISPQAKALLQDKDVIAIN... | glycoside catabolic process glycosphingolipid catabolic process glycosylceramide catabolic process negative regulation of nitric oxide biosynthetic process negative regulation of nitric-oxide synthase activity oligosaccharide metabolic process azurophil granule lumen; cytoplasm; extracellular exosome; extracellular reg... |
amyloid-beta metabolic process angiotensin maturation cell maturation cellular response to xenobiotic stimulus drinking behavior hormone-mediated signaling pathway juxtaglomerular apparatus development kidney development male gonad development mesonephros development proteolysis regulation of blood pressure regulation ... | apical part of cell; extracellular space; membrane | aspartic-type endopeptidase activity endopeptidase activity insulin-like growth factor receptor binding peptidase activity signaling receptor binding | Mus musculus | 3D-structure Aspartyl protease Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Membrane Protease Reference proteome Secreted Signal Zymogen | MDRRRMPLWA | MDRRRMPLWALLLLWSPCTFSLPTRTATFERIPLKKMPSVREILEERGVDMTRLSAEWGVFTKRPSLTNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIPFMLAKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRIEEYVVN... | amyloid-beta metabolic process angiotensin maturation cell maturation cellular response to xenobiotic stimulus drinking behavior hormone-mediated signaling pathway juxtaglomerular apparatus development kidney development male gonad development mesonephros development proteolysis regulation of blood pressure regulation ... |
photorespiration reductive pentose-phosphate cycle | chloroplast | magnesium ion binding monooxygenase activity ribulose-bisphosphate carboxylase activity | Marchantia polymorpha | Acetylation Calvin cycle Carbon dioxide fixation Chloroplast Direct protein sequencing Disulfide bond Lyase Magnesium Metal-binding Methylation Monooxygenase Oxidoreductase Photorespiration Photosynthesis Plastid | MSPQTETKAG | MSPQTETKAGVGFKAGVKDYRLTYYTPDYETKDTDILAAFRMTPQPGVPAEEAGNAVAAESSTGTWTTVWTDGLTNLDRYKGRCYDIDPVPGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYTKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFVAEAIYKSQAETGEIKGHYLNATAGTCEEMLKRAACARELGVPIVMHDYLTGGFTANTSLAFYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRM... | photorespiration reductive pentose-phosphate cycle chloroplast magnesium ion binding monooxygenase activity ribulose-bisphosphate carboxylase activity Marchantia polymorpha Acetylation Calvin cycle Carbon dioxide fixation Chloroplast Direct protein sequencing Disulfide bond Lyase Magnesium Metal-binding Methylation Mo... |
adrenal gland development female pregnancy glucocorticoid biosynthetic process inflammatory response locomotory exploration behavior lung development negative regulation of epinephrine secretion negative regulation of glucagon secretion positive regulation of corticotropin secretion positive regulation of cortisol secr... | extracellular space; neuronal cell body; synapse | corticotropin-releasing hormone activity | Sus scrofa | Amidation Cleavage on pair of basic residues Direct protein sequencing Hormone Reference proteome Secreted Signal | MRLPLLVSAG | MRLPLLVSAGVLLVALLPCPPCRALLSRGPVLGARQAPQHPQALDFLQPQQQPQQPQPRPVLLRMGEEYFLRLGNLNKSPAAPLSPASSPLTGSSGNRPDEVAANFFRALLQQLPLPRRPLDSPSGPAERGAENALSSRQEAPERERRSEEPPISLDLTFHLLREVLEMARAEQLAQQAHSNRKLMEIIGK | adrenal gland development female pregnancy glucocorticoid biosynthetic process inflammatory response locomotory exploration behavior lung development negative regulation of epinephrine secretion negative regulation of glucagon secretion positive regulation of corticotropin secretion positive regulation of cortisol secr... |
neuropeptide signaling pathway | extracellular region | hormone activity | Xenopus laevis | Amidation Cleavage on pair of basic residues Direct protein sequencing Endorphin Glycoprotein Hormone Pyrrolidone carboxylic acid Reference proteome Secreted Signal | MFRPLWGCFL | MFRPLWGCFLAILGICIFHIGEVQSQCWESSRCADLSSEDGVLECIKACKTDLSAESPVFPGNGHLQPLSESIRKYVMTHFRWNKFGRRNSTGNDGSNTGYKREDISSYPVFSLFPLSDQNAPGDNMEEEPLDRQENKRAYSMEHFRWGKPVGRKRRPIKVYPNGVEEESAESYPMELRRELSLELDYPEIDLDEDIEDNEVESALTKKNGNYRMHHFRWGSPPKDKRYGGFMTPERSQTPLMTLFKNAIIKNSHKKGQ | neuropeptide signaling pathway extracellular region hormone activity Xenopus laevis Amidation Cleavage on pair of basic residues Direct protein sequencing Endorphin Glycoprotein Hormone Pyrrolidone carboxylic acid Reference proteome Secreted Signal MFRPLWGCFL MFRPLWGCFLAILGICIFHIGEVQSQCWESSRCADLSSEDGVLECIKACKTDLSAESPVF... |
neuropeptide signaling pathway | extracellular region | hormone activity | Xenopus laevis | Amidation Cleavage on pair of basic residues Direct protein sequencing Endorphin Glycoprotein Hormone Pyrrolidone carboxylic acid Reference proteome Secreted Signal | MFRPTGGCSL | MFRPTGGCSLAILGVFIFHIGEVQSQCWESSRCADLSSEDGILECIKACKMDLSAESPVFPGNGHLQPLSESIRKYVMTHFRWNKFGRRNNTGNDGSSGGYKREDISNYPVLNLFPSSDNQNAQGDNMEEEPMDRQENKRAYSMEHFRWGKPVGRKRRPIKVYPNGVEEESAESFPMELRRELSLELDYPEIDLDEDIEDNEVERALTKKNGNYRMHHFRWGSPPKDKRYGGFMTPERSQTPLMTLFKNAIIKNTHKKGL | neuropeptide signaling pathway extracellular region hormone activity Xenopus laevis Amidation Cleavage on pair of basic residues Direct protein sequencing Endorphin Glycoprotein Hormone Pyrrolidone carboxylic acid Reference proteome Secreted Signal MFRPTGGCSL MFRPTGGCSLAILGVFIFHIGEVQSQCWESSRCADLSSEDGILECIKACKMDLSAESPVF... |
chemical synaptic transmission neuropeptide signaling pathway response to immobilization stress response to nicotine sensory perception | axon terminus; dendrite; dendritic spine; dense core granule; extracellular space; Golgi apparatus; hippocampal mossy fiber to CA3 synapse; neuronal cell body; neuronal dense core vesicle; neuronal dense core vesicle lumen; plasma membrane; synaptic vesicle | opioid peptide activity opioid receptor binding | Rattus norvegicus | Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Endorphin Neuropeptide Neurotransmitter Opioid peptide Reference proteome Secreted Signal | MAWSRLMLAA | MAWSRLMLAACLLVIPSEVAADCLSLCSLCAVRTQDGPHPINPLICSLECQDLVPPSEEWETCRGFWSFLTLTASGLHGKDDLENEVALEEGYTALTKLLEPLLKELEKGQLLTSVSEEKLRGLSSRFGNGRESELLGTDLMNDEAAQAGTLHFNEEDLRKQAKRYGGFLRKYPKRSSEMTGDEDRGQDGDQVGHEDLYKRYGGFLRRIRPKLKWDNQKRYGGFLRRQFKVVTRSQENPNTYSEDLDV | chemical synaptic transmission neuropeptide signaling pathway response to immobilization stress response to nicotine sensory perception axon terminus; dendrite; dendritic spine; dense core granule; extracellular space; Golgi apparatus; hippocampal mossy fiber to CA3 synapse; neuronal cell body; neuronal dense core vesi... |
cell differentiation chromatin organization negative regulation of apoptotic process positive regulation of NF-kappaB transcription factor activity positive regulation of transcription by RNA polymerase II | nucleus | DNA-binding transcription factor binding histone binding histone chaperone activity ion binding | Rattus norvegicus | Acetylation Direct protein sequencing Isopeptide bond Nucleus Phosphoprotein Reference proteome Ubl conjugation | MSDAAVDTSS | MSDAAVDTSSEITTKDLKEKKEVVEEAENGRDAPANGNAQNEENGEQEADNEVDEEEEEGGEEEEEEEEGDGEEEDGDEDEEAEAPTGKRVAEDDEDDDVETKKQKKTDEDD | cell differentiation chromatin organization negative regulation of apoptotic process positive regulation of NF-kappaB transcription factor activity positive regulation of transcription by RNA polymerase II nucleus DNA-binding transcription factor binding histone binding histone chaperone activity ion binding Rattus nor... |
axonogenesis digestion eating behavior neuron migration signal transduction | axon; extracellular region; extracellular space | hormone activity neuropeptide hormone activity peptide hormone receptor binding | Homo sapiens | 3D-structure Amidation Cleavage on pair of basic residues Glycoprotein Hormone Proteoglycan Reference proteome Secreted Signal Sulfation | MNSGVCLCVL | MNSGVCLCVLMAVLAAGALTQPVPPADPAGSGLQRAEEAPRRQLRVSQRTDGESRAHLGALLARYIQQARKAPSGRMSIVKNLQNLDPSHRISDRDYMGWMDFGRRSAEEYEYPS | axonogenesis digestion eating behavior neuron migration signal transduction axon; extracellular region; extracellular space hormone activity neuropeptide hormone activity peptide hormone receptor binding Homo sapiens 3D-structure Amidation Cleavage on pair of basic residues Glycoprotein Hormone Proteoglycan Reference p... |
adaptive immune response immune response | blood microparticle; extracellular region; extracellular space; immunoglobulin complex; plasma membrane | antigen binding | Homo sapiens | 3D-structure Adaptive immunity Cell membrane Direct protein sequencing Disulfide bond Immunity Immunoglobulin Immunoglobulin domain Membrane Reference proteome Secreted Signal | MVLQTQVFIS | MVLQTQVFISLLLWISGAYGDIVMTQSPDSLAVSLGERATINCKSSQSVLYSSNNKNYLAWYQQKPGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYSTP | adaptive immune response immune response blood microparticle; extracellular region; extracellular space; immunoglobulin complex; plasma membrane antigen binding Homo sapiens 3D-structure Adaptive immunity Cell membrane Direct protein sequencing Disulfide bond Immunity Immunoglobulin Immunoglobulin domain Membrane Refer... |
adaptive immune memory response antibacterial humoral response antibody-dependent cellular cytotoxicity B cell antigen processing and presentation B cell differentiation B cell proliferation B cell receptor signaling pathway complement activation, classical pathway eosinophil degranulation Fc receptor-mediated immune c... | cytoplasm; extracellular space; IgE B cell receptor complex; immunoglobulin complex, circulating; plasma membrane | antigen binding immunoglobulin receptor binding | Mus musculus | Cell membrane Disulfide bond Glycoprotein Immunoglobulin domain Membrane Reference proteome Secreted | SIRNPQLYPL | SIRNPQLYPLKPCKGTASMTLGCLVKDYFPNPVTVTWYSDSLNMSTVNFPALGSELKVTTSQVTSWGKSAKNFTCHVTHPPSFNESRTILVRPVNITEPTLELLHSSCDPNAFHSTIQLYCFIYGHILNDVSVSWLMDDREITDTLAQTVLIKEEGKLASTCSKLNITEQQWMSESTFTCKVTSQGVDYLAHTRRCPDHEPRGVITYLIPPSPLDLYQNGAPKLTCLVVDLESEKNVNVTWNQEKKTSVSASQWYTKHHNNATTSITSILPVVAKDWIEGYGYQCIVDHPDFPKPIVRSITKTPGQRSAPEVYVFPPPEE... | adaptive immune memory response antibacterial humoral response antibody-dependent cellular cytotoxicity B cell antigen processing and presentation B cell differentiation B cell proliferation B cell receptor signaling pathway complement activation, classical pathway eosinophil degranulation Fc receptor-mediated immune c... |
adaptive immune response antigen processing and presentation of exogenous peptide antigen via MHC class II negative regulation of antigen processing and presentation of peptide antigen via MHC class II peptide antigen assembly with MHC class II protein complex positive regulation of immune response positive regulation ... | late endosome membrane; lysosomal membrane; MHC class II protein complex; plasma membrane | MHC class II protein complex binding MHC class II receptor activity peptide antigen binding | Homo sapiens | 3D-structure Adaptive immunity Disulfide bond Endosome Glycoprotein Immunity Lysosome Membrane MHC II Reference proteome Signal Transmembrane Transmembrane helix | MALRAGLVLG | MALRAGLVLGFHTLMTLLSPQEAGATKADHMGSYGPAFYQSYGASGQFTHEFDEEQLFSVDLKKSEAVWRLPEFGDFARFDPQGGLAGIAAIKAHLDILVERSNRSRAINVPPRVTVLPKSRVELGQPNILICIVDNIFPPVINITWLRNGQTVTEGVAQTSFYSQPDHLFRKFHYLPFVPSAEDVYDCQVEHWGLDAPLLRHWELQVPIPPPDAMETLVCALGLAIGLVGFLVGTVLIIMGTYVSSVPR | adaptive immune response antigen processing and presentation of exogenous peptide antigen via MHC class II negative regulation of antigen processing and presentation of peptide antigen via MHC class II peptide antigen assembly with MHC class II protein complex positive regulation of immune response positive regulation ... |
adaptive immune response antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of peptide antigen immune response peptide antigen assembly with MHC class II protein complex positive regulation of immune response positive... | cell surface; early endosome; external side of plasma membrane; Golgi apparatus; late endosome membrane; lysosomal membrane; membrane; MHC class II protein complex; multivesicular body; plasma membrane | MHC class II protein complex binding peptide antigen binding protein-containing complex binding | Mus musculus | Adaptive immunity Disulfide bond Glycoprotein Immunity Membrane MHC II Reference proteome Signal Transmembrane Transmembrane helix Ubl conjugation | MALQIPSLLL | MALQIPSLLLSAAVVVLMVLSSPRTEGGNSERHFVAQLKGECYFTNGTQRIRSVNRYIYNREEWVRFDSDVGEYRAVTELGRPDAEYWNSQPEILERTRAEVDTVCRHNYEGVETHTSLRRLEQPNVAISLSRTEALNHHNTLVCSVTDFYPAKIKVRWFRNGQEETVGVSSTQLIRNGDWTFQVLVMLEMTPHQGEVYTCHVEHPSLKSPITVEWRAQSESARSKMLSGIGGCVLGVIFLGLGLFIRHRSQKGPRGPPPAGLLQ | adaptive immune response antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of peptide antigen immune response peptide antigen assembly with MHC class II protein complex positive regulation of immune response positive... |
adaptive immune response antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of peptide antigen immune response peptide antigen assembly with MHC class II protein complex positive regulation of immune response positive... | cell surface; early endosome; external side of plasma membrane; Golgi apparatus; late endosome membrane; lysosomal membrane; membrane; MHC class II protein complex; multivesicular body; plasma membrane | MHC class II protein complex binding peptide antigen binding protein-containing complex binding | Mus musculus | 3D-structure Adaptive immunity Disulfide bond Glycoprotein Immunity Membrane MHC II Reference proteome Signal Transmembrane Transmembrane helix Ubl conjugation | MALQIPSLLL | MALQIPSLLLLAAVVVLTVLSSPGTEGGNSERHFVHQFQPFCYFTNGTQRIRLVIRYIYNREEYVRFDSDVGEYRAVTELGRPDAEYWNKQYLERTRAELDTVCRHNYEKTETPTSLRRLEQPSVVISLSRTEALNHHNTLVCSVTDFYPAKIKVRWFRNGQEETVGVSSTQLIRNGDWTFQVLVMLEMTPRRGEVYTCHVEHPSLKSPITVEWRAQSESARSKMLSGIGGCVLGVIFLGLGLFIRHRSQKGPRGPPPAGLLQ | adaptive immune response antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of peptide antigen immune response peptide antigen assembly with MHC class II protein complex positive regulation of immune response positive... |
adaptive immune response antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of peptide antigen immune response peptide antigen assembly with MHC class II protein complex positive regulation of immune response positive... | cell surface; early endosome; external side of plasma membrane; Golgi apparatus; late endosome membrane; lysosomal membrane; membrane; MHC class II protein complex; multivesicular body; plasma membrane | MHC class II protein complex binding peptide antigen binding protein-containing complex binding | Mus musculus | Adaptive immunity Disulfide bond Glycoprotein Immunity Membrane MHC II Reference proteome Signal Transmembrane Transmembrane helix Ubl conjugation | MALQIPSLLL | MALQIPSLLLSAAVVVLMVLSSPGTEGGDSERHFVFQFKGECYFTNGTQRIRSVDRYIYNREEYLRFDSDVGEYRAVTELGRPDAEYYNKQYLEQTRAELDTVCRHNYEGVETHTSLRRLEQPNVVISLSRTEALNHHNTLVCSVTDFYPAKIKVRWFRNGQEETVGVSSTQLISNGDWTFQVLVMLEMTPRRGEVYTCHVEHPSLKSPITVEWRAQSESARSKMLSGIGGCVLGVIFLGLGLFIRHRSQKGPRGPPPAGLLQ | adaptive immune response antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of peptide antigen immune response peptide antigen assembly with MHC class II protein complex positive regulation of immune response positive... |
adaptive immune response antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of peptide antigen immune response peptide antigen assembly with MHC class II protein complex positive regulation of immune response positive... | cell surface; early endosome; external side of plasma membrane; Golgi apparatus; late endosome membrane; lysosomal membrane; membrane; MHC class II protein complex; multivesicular body; plasma membrane | MHC class II protein complex binding peptide antigen binding protein-containing complex binding | Mus musculus | Adaptive immunity Disulfide bond Glycoprotein Immunity Membrane MHC II Reference proteome Signal Transmembrane Transmembrane helix Ubl conjugation | AAVVVLMVLS | AAVVVLMVLSSPGTEGGNSERHFVSQFKGECYFTNGTQRIRSVDRYIYNREEYLRFDSDVGEYRAVTELGRSDAEYYNKQYLERTRAELDTVCRHNYEGVETPTSLRRLEQPNVVISLSRTEALNHHNTLVCSVTDFYPAKIKVRWFRNGQEETVGVSSTQLIRNGDWTFQVLVMLEMAPRRGEVYTCHVEHPSLKSPITVEWRAQSESARSKMLSGIGGCVLGVIFLGLGLFIRYRSQKGPRGPPPAGLLQ | adaptive immune response antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of peptide antigen immune response peptide antigen assembly with MHC class II protein complex positive regulation of immune response positive... |
binding of sperm to zona pellucida cell differentiation chromosome condensation flagellated sperm motility negative regulation of DNA recombination nucleosome assembly spermatogenesis | condensed nuclear chromosome; nucleosome; nucleus | DNA binding double-stranded DNA binding nucleosomal DNA binding structural constituent of chromatin | Rattus norvegicus | Chromosome Citrullination Developmental protein Differentiation Direct protein sequencing DNA-binding Nucleus Phosphoprotein Reference proteome Spermatogenesis | MSETAPAASS | MSETAPAASSTLVPAPVEKPATKRRGKKPGMATARKPRGFSVSKLIPEALSMSQERAGMSLAALKKALAAAGYDVEKNNSRIKLALKRLVNKGVLVQTKGTGASGSFKLSKKAASGNDKGKGKKSASAKAKKLGLSRASRSPKSSKTKVVKKPKATPTKGSGSRRKTKGAKGLQQRKSPAKARATNSNSGKSKMVMQKTDLRKAAGRK | binding of sperm to zona pellucida cell differentiation chromosome condensation flagellated sperm motility negative regulation of DNA recombination nucleosome assembly spermatogenesis condensed nuclear chromosome; nucleosome; nucleus DNA binding double-stranded DNA binding nucleosomal DNA binding structural constituent... |
defense response to bacterium nucleosome assembly | extracellular region; nucleosome; nucleus | DNA binding structural constituent of chromatin | Oncorhynchus mykiss | Acetylation Antibiotic Antimicrobial Chromosome Direct protein sequencing DNA-binding Nucleus Secreted | MAEVAPAPAA | MAEVAPAPAAAAPAKAPKKKAAAKPKKAGPSVGELIVKAVSASKERSGVSLAALKKSLAAGGYDVEKNNSRVKIAVKSLVTKGTLVQTKGTGASGSFKLNKKAVEAKKPAKKAAAPKAKKVAAKKPAAAKKPKKVAAKKAVAAKKSPKKAKKPATPKKAAKSPKKVKKPAAAAKKAAKSPKKATKAAKPKAAKPKAAKAKKAAPKKK | defense response to bacterium nucleosome assembly extracellular region; nucleosome; nucleus DNA binding structural constituent of chromatin Oncorhynchus mykiss Acetylation Antibiotic Antimicrobial Chromosome Direct protein sequencing DNA-binding Nucleus Secreted MAEVAPAPAA MAEVAPAPAAAAPAKAPKKKAAAKPKKAGPSVGELIVKAVSASKE... |
cytoplasmic translation maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosomal small subunit assembly translation | 90S preribosome; cytosol; cytosolic small ribosomal subunit; nucleolus; nucleoplasm; small-subunit processome | mRNA binding structural constituent of ribosome | Saccharomyces cerevisiae | 3D-structure Acetylation Cytoplasm Nucleus Reference proteome Ribonucleoprotein Ribosomal protein Ribosome biogenesis rRNA processing | MSNVVQARDN | MSNVVQARDNSQVFGVARIYASFNDTFVHVTDLSGKETIARVTGGMKVKADRDESSPYAAMLAAQDVAAKCKEVGITAVHVKIRATGGTRTKTPGPGGQAALRALARSGLRIGRIEDVTPVPSDSTRKKGGRRGRRL | cytoplasmic translation maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosomal small subunit assembly translation 90S preribosome; cytosol; cytosolic small ribosomal subunit; nucleolus; nucleoplasm; small-subunit processome mRNA binding structural constituent of ribosome Sacc... |
epidermis development epithelial cell differentiation intermediate filament organization positive regulation of epidermis development protein heterotetramerization | cell surface; cytoplasm; cytoskeleton; extracellular region; keratin filament | protein heterodimerization activity structural constituent of skin epidermis | Bos taurus | Coiled coil Cytoplasm Disulfide bond Intermediate filament Keratin Phosphoprotein Reference proteome Secreted | MSVRYSSSKQ | MSVRYSSSKQYSSSRSGGGGGGGSSLRISSSKGSLGGGYSSGGFSGGSFSRGSSAGGCFGGSSSIYGGGLGSGFGGGYGSSFGGSYGGSFGGGYGGGGFGGGSFGGGSFGGGLGGGFGDGGLISGNQKITMQNLNDRLASYLDKVRALEESNYELEVKIKEWYEKYGNSRQREPRDYSKYYQTIDDLKNQIFNLTTDNANILIQVDNARLAADDFRLKYENEVTLRQSVEADINGLRRVLDELTLTKTDLEMQIESLTEELAYLKKNHEEEMRDLQNVSTGDVNVEMNAAPGVDLTELLNNMRSQYEQLAEKNRRDAEAW... | epidermis development epithelial cell differentiation intermediate filament organization positive regulation of epidermis development protein heterotetramerization cell surface; cytoplasm; cytoskeleton; extracellular region; keratin filament protein heterodimerization activity structural constituent of skin epidermis B... |
cell-cell signaling glandular epithelial cell maturation intracellular steroid hormone receptor signaling pathway lung alveolus development negative regulation of gene expression ovulation from ovarian follicle paracrine signaling positive regulation of gene expression positive regulation of transcription by RNA polyme... | chromatin; cytosol; mitochondrial outer membrane; nucleoplasm; plasma membrane | ATPase binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific enzyme binding estrogen response element binding G protein-coupled receptor activity identical protein binding nuclear receptor activity nuclear stero... | Homo sapiens | 3D-structure Alternative promoter usage Alternative splicing Cytoplasm Direct protein sequencing DNA-binding Isopeptide bond Lipid-binding Lipoprotein Membrane Metal-binding Mitochondrion Mitochondrion outer membrane Nucleus Palmitate Phosphoprotein Receptor Reference proteome Steroid-binding Transcription Transcriptio... | MTELKAKGPR | MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAIPISLDGLLFPRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGCKVGDSSGTAAAHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTVMDFIHVPILPLNHALLAART... | cell-cell signaling glandular epithelial cell maturation intracellular steroid hormone receptor signaling pathway lung alveolus development negative regulation of gene expression ovulation from ovarian follicle paracrine signaling positive regulation of gene expression positive regulation of transcription by RNA polyme... |
viral entry into host cell virion attachment to host cell | host cell endosome membrane; host cell Golgi membrane; host cell plasma membrane; membrane; viral envelope; virion membrane | identical protein binding | Human herpesvirus 1 | 3D-structure Disulfide bond Glycoprotein Host cell membrane Host endosome Host Golgi apparatus Host membrane Host-virus interaction Membrane Phosphoprotein Signal Transmembrane Transmembrane helix Ubl conjugation Viral attachment to host cell Viral envelope protein Virion Virus entry into host cell | MHQGAPSWGR | MHQGAPSWGRRWFVVWALLGLTLGVLVASAAPTSPGTPGVAAATQAANGGPATPAPPPLGAAPTGDPKPKKNKKPKNPTPPRPAGDNATVAAGHATLREHLRDIKAENTDANFYVCPPPTGATVVQFEQPRRCPTRPEGQNYTEGIAVVFKENIAPYKFKATMYYKDVTVSQVWFGHRYSQFMGIFEDRAPVPFEEVIDKINAKGVCRSTAKYVRNNLETTAFHRDDHETDMELKPANAATRTSRGWHTTDLKYNPSRVEAFHRYGTTVNCIVEEVDARSVYPYDEFVLATGDFVYMSPFYGYREGSHTEHTTYAADRFK... | viral entry into host cell virion attachment to host cell host cell endosome membrane; host cell Golgi membrane; host cell plasma membrane; membrane; viral envelope; virion membrane identical protein binding Human herpesvirus 1 3D-structure Disulfide bond Glycoprotein Host cell membrane Host endosome Host Golgi appar... |
protein complex oligomerization viral entry into host cell virion attachment to host cell virus-mediated pore formation in host cell membrane | host cell membrane; host multivesicular body; membrane; T=pseudo3 icosahedral viral capsid | monoatomic ion channel activity structural molecule activity | Human hepatitis A virus genotype IA ) | Capsid protein Host endosome Host membrane Host-virus interaction Ion channel Ion transport Membrane T=pseudo3 icosahedral capsid protein Transport Viral attachment to host cell Viral ion channel Virion Virus entry into host cell | MNMSKQGIFQ | MNMSKQGIFQTVGSGLDHILSLADIEEEQMIQSVVRTAVTGASYFTSVDQSSVHTAEVGLHQIEPLKTSVDKPSSKKTQGEKFFLIHSADWLTTHALFHEVAKLDVVKLLYNEQFAVQGLLRYHTYARFGIEIQVQINPTPFQQGGLICAMVPSDQSYGSIASLTVYPHGLLNCNINNVVRIKVPFIYTRGAYHFKDPQYPVWELTIRVWSELNIGTGTSAYTSLNVLARFTDLELHGLTPLSTQMMRNEFRVSTTENVVNLSNYEDARAKMSFALDQEDWKSDPSQGGGIKITHFTTWTSIPTLAAQFPFNASDSVGQQ... | protein complex oligomerization viral entry into host cell virion attachment to host cell virus-mediated pore formation in host cell membrane host cell membrane; host multivesicular body; membrane; T=pseudo3 icosahedral viral capsid monoatomic ion channel activity structural molecule activity Human hepatitis A virus ge... |
viral budding via host ESCRT complex | host cell cytoplasm; host cell plasma membrane; membrane; virion component | structural constituent of virion | Sendai virus ) | Host cell membrane Host cytoplasm Host membrane Host-virus interaction Membrane Phosphoprotein Viral budding Viral budding via the host ESCRT complexes Viral matrix protein Viral release from host cell Virion | MADIYRFPKF | MADIYRFPKFSYEDNGTVEPLPLRTGPDKKAIPHIRIVKVGDPPKHGVRYLDLLLLGFFETPKQTTNLGSVSDLTEPTSYSICGSGSLPIGVAKYYGTDQELLKACTDLRITVRRTVRAGEMIVYMVDSIGAPLLPWSGRLRQGMIFNANKVALAPQCLPVDKDIRLRVVFVNGTSLGAITIAKIPKTLADLALPNSISVNLLVTLKTGISTEQKGVLPVLDDQGEKKLNFMVHLGLIRRKVGKIYSVEYCKSKIERMRLIFSLGLIGGISFHVQVNGTLSKTFMSQLAWKRAVCFPLMDVNPHMNMVIWAASVEITGVD... | viral budding via host ESCRT complex host cell cytoplasm; host cell plasma membrane; membrane; virion component structural constituent of virion Sendai virus )Host cell membrane Host cytoplasm Host membrane Host-virus interaction Membrane Phosphoprotein Viral budding Viral budding via the host ESCRT complexes Viral m... |
DNA-templated transcription negative regulation of apoptotic process positive regulation of transcription by RNA polymerase II | cytosol; nucleoplasm; nucleus | DNA-binding transcription factor binding histone binding ion binding | Homo sapiens | 3D-structure Acetylation Alternative splicing Direct protein sequencing Isopeptide bond Nucleus Phosphoprotein Reference proteome Ubl conjugation | MSDAAVDTSS | MSDAAVDTSSEITTKDLKEKKEVVEEAENGRDAPANGNAENEENGEQEADNEVDEEEEEGGEEEEEEEEGDGEEEDGDEDEEAESATGKRAAEDDEDDDVDTKKQKTDEDD | DNA-templated transcription negative regulation of apoptotic process positive regulation of transcription by RNA polymerase II cytosol; nucleoplasm; nucleus DNA-binding transcription factor binding histone binding ion binding Homo sapiens 3D-structure Acetylation Alternative splicing Direct protein sequencing Isopeptid... |
DNA-templated transcription modulation by symbiont of host protein ubiquitination negative regulation of DNA-templated transcription perturbation by virus of host apoptosis suppression by virus of host type I interferon-mediated signaling pathway suppression by virus of host viral-induced cytoplasmic pattern recognitio... | host cell cytoplasm; host cell nucleus | DNA binding PDZ domain binding zinc ion binding | Human papillomavirus type 18 | 3D-structure Activator DNA-binding Early protein Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host IRF3 by virus Inhibition of host RLR pathway by virus Metal-binding Modulation of host cell apoptosis by virus Oncogene Reference proteome Transcripti... | MARFEDPTRR | MARFEDPTRRPYKLPDLCTELNTSLQDIEITCVYCKTVLELTEVFEFAFKDLFVVYRDSIPHAACHKCIDFYSRIRELRHYSDSVYGDTLEKLTNTGLYNLLIRCLRCQKPLNPAEKLRHLNEKRRFHNIAGHYRGQCHSCCNRARQERLQRRRETQV | DNA-templated transcription modulation by symbiont of host protein ubiquitination negative regulation of DNA-templated transcription perturbation by virus of host apoptosis suppression by virus of host type I interferon-mediated signaling pathway suppression by virus of host viral-induced cytoplasmic pattern recognitio... |
biological process involved in interaction with host DNA-templated viral transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II protein-containing complex assembly regulation of viral transcription | host cell cytoplasm; host cell cytoplasmic vesicle; host cell nucleus; host cell perinuclear region of cytoplasm; replication compartment; transcription regulator complex; viral tegument | core promoter sequence-specific DNA binding DNA binding DNA-binding transcription factor activity DNA-binding transcription factor binding molecular function activator activity RNA polymerase II cis-regulatory region sequence-specific DNA binding structural constituent of virion transcription coactivator activity | Human herpesvirus 1 | 3D-structure DNA-binding Host nucleus Host-virus interaction Phosphoprotein Reference proteome Transcription Transcription regulation Virion Virion tegument | MDLLVDELFA | MDLLVDELFADMNADGASPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAALFNRLLDDLGFSAGPALCTMLDTWNEDLFSALPTNADLYRECKFLSTLPSDVVEWGDAYVPERTQIDIRAHGDVAFPTLPATRDGLGLYYEALSRFFHAELRAREESYRTVLANFCSALYRYLRASVRQLHRQAHMRGRDRDLGEMLRATIADRYYRETARLARVLFLHLYLFLTREILWAAYAEQMMRPDLFDCLCCDLESWRQLAGLFQPFMFVNGALTVRGVPIEARRLRELNHIREHLNLPLVRSAATEEPGAPLT... | biological process involved in interaction with host DNA-templated viral transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II protein-containing complex assembly regulation of viral transcription host cell cytoplasm; host cell cytoplasmic vesicle; ho... |
cellular response to hypoxia positive regulation of cellular response to hypoxia response to abscisic acid response to caffeine response to cold response to estradiol response to flooding response to hydrogen peroxide response to hypoxia response to osmotic stress response to salt stress response to sucrose response to... | cytosol; plasma membrane | alcohol dehydrogenase (NAD+) activity nucleotide binding protein homodimerization activity zinc ion binding | Arabidopsis thaliana | 3D-structure Acetylation Cytoplasm Glutathionylation Metal-binding NAD Nucleotide-binding Oxidoreductase Phosphoprotein Reference proteome Zinc | MSTTGQIIRC | MSTTGQIIRCKAAVAWEAGKPLVIEEVEVAPPQKHEVRIKILFTSLCHTDVYFWEAKGQTPLFPRIFGHEAGGIVESVGEGVTDLQPGDHVLPIFTGECGECRHCHSEESNMCDLLRINTERGGMIHDGESRFSINGKPIYHFLGTSTFSEYTVVHSGQVAKINPDAPLDKVCIVSCGLSTGLGATLNVAKPKKGQSVAIFGLGAVGLGAAEGARIAGASRIIGVDFNSKRFDQAKEFGVTECVNPKDHDKPIQQVIAEMTDGGVDRSVECTGSVQAMIQAFECVHDGWGVAVLVGVPSKDDAFKTHPMNFLNERTLKGT... | cellular response to hypoxia positive regulation of cellular response to hypoxia response to abscisic acid response to caffeine response to cold response to estradiol response to flooding response to hydrogen peroxide response to hypoxia response to osmotic stress response to salt stress response to sucrose response to... |
asymmetric cell division cell septum assembly detection of stimulus phosphorelay signal transduction system positive regulation of DNA-templated transcription positive regulation of sporulation resulting in formation of a cellular spore single-species surface biofilm formation sporulation resulting in formation of a ce... | cytoplasm | calcium ion binding DNA binding DNA-binding transcription factor activity | Bacillus subtilis | 3D-structure Activator Calcium Cytoplasm DNA-binding Metal-binding Phosphoprotein Reference proteome Repressor Sporulation Transcription Transcription regulation Two-component regulatory system | MEKIKVCVAD | MEKIKVCVADDNRELVSLLSEYIEGQEDMEVIGVAYNGQECLSLFKEKDPDVLVLDIIMPHLDGLAVLERLRESDLKKQPNVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLVGHIRQVSGNASSVTHRAPSSQSSIIRSSQPEPKKKNLDASITSIIHEIGVPAHIKGYLYLREAISMVYNDIELLGSITKVLYPDIAKKFNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVSMTKAKPTNSEFIAMVADKLRLEHKAS | asymmetric cell division cell septum assembly detection of stimulus phosphorelay signal transduction system positive regulation of DNA-templated transcription positive regulation of sporulation resulting in formation of a cellular spore single-species surface biofilm formation sporulation resulting in formation of a ce... |
angiogenesis ATP biosynthetic process cellular response to interleukin-7 generation of precursor metabolites and energy lipid metabolic process negative regulation of cell adhesion involved in substrate-bound cell migration osteoblast differentiation positive regulation of blood vessel endothelial cell migration proton... | cell surface; extracellular exosome; membrane; mitochondrial inner membrane; mitochondrial matrix; mitochondrial membrane; mitochondrial nucleoid; mitochondrial proton-transporting ATP synthase complex; mitochondrial proton-transporting ATP synthase, catalytic core; mitochondrion; nucleus; plasma membrane; proton-trans... | angiostatin binding ATP binding ATP hydrolysis activity MHC class I protein binding proton-transporting ATP synthase activity, rotational mechanism proton-transporting ATPase activity, rotational mechanism | Homo sapiens | 3D-structure Acetylation ATP synthesis ATP-binding CF(1) Direct protein sequencing Disease variant Glycoprotein Hydrogen ion transport Ion transport Membrane Mitochondrion Mitochondrion inner membrane Nucleotide-binding Phosphoprotein Reference proteome Transit peptide Translocase Transport | MLGFVGRVAA | MLGFVGRVAAAPASGALRRLTPSASLPPAQLLLRAAPTAVHPVRDYAAQTSPSPKAGAATGRIVAVIGAVVDVQFDEGLPPILNALEVQGRETRLVLEVAQHLGESTVRTIAMDGTEGLVRGQKVLDSGAPIKIPVGPETLGRIMNVIGEPIDERGPIKTKQFAPIHAEAPEFMEMSVEQEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVINLKDATSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSA... | angiogenesis ATP biosynthetic process cellular response to interleukin-7 generation of precursor metabolites and energy lipid metabolic process negative regulation of cell adhesion involved in substrate-bound cell migration osteoblast differentiation positive regulation of blood vessel endothelial cell migration proton... |
cell adhesion innate immune response intracellular potassium ion homeostasis intracellular sodium ion homeostasis potassium ion import across plasma membrane sodium ion export across plasma membrane | apical plasma membrane; sarcolemma; sodium:potassium-exchanging ATPase complex | ATPase activator activity | Canis lupus familiaris | Cell adhesion Cell membrane Direct protein sequencing Disulfide bond Glutathionylation Glycoprotein Immunity Innate immunity Ion transport Membrane Phosphoprotein Potassium Potassium transport Reference proteome Signal-anchor Sodium Sodium transport Sodium/potassium transport Transmembrane Transmembrane helix Transport | MARGKAKEEG | MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPGLTQIPQIQKTEISFRPNDPKSYEEYVRNIVRFLEKYKDSAQKDEMIFEDCGNMPSEIKERGEFNNERGERKVCRFKLEWLGNCSGINDETYGYRDGKPCVLIKLNRVLGFKPKPPKNESLEAYPVMKYSPYVLPVQCTGKRDEDKDRIGNVEYFGLGGYPGFPLQYYPYYGKLLQPKYLQPLLAVQFTNLTMDTEIRIECKAYGENIGYSEKDRFQGRFDVKIEVKS | cell adhesion innate immune response intracellular potassium ion homeostasis intracellular sodium ion homeostasis potassium ion import across plasma membrane sodium ion export across plasma membrane apical plasma membrane; sarcolemma; sodium:potassium-exchanging ATPase complex ATPase activator activity Canis lupus fami... |
photosynthetic electron transport in photosystem II response to herbicide | chloroplast thylakoid membrane; photosystem II | chlorophyll binding electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity iron ion binding oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor oxygen evolving activity | Pisum sativum | 3D-structure Acetylation Calcium Chlorophyll Chloroplast Chromophore Direct protein sequencing Electron transport Herbicide resistance Iron Magnesium Manganese Membrane Metal-binding Oxidoreductase Phosphoprotein Photosynthesis Photosystem II Plastid Thylakoid Transmembrane Transmembrane helix Transport | MTAILERRDS | MTAILERRDSENLWGRFCNWITSTENRLYIGWFGVLMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIIPTSAAIGLHFYPIWEAASVDEWLYNGGPYELIVLHFLLGVACYMGREWELSFRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANEGYRFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVINTWADI... | photosynthetic electron transport in photosystem II response to herbicide chloroplast thylakoid membrane; photosystem II chlorophyll binding electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity iron ion binding oxidoreductase activity, acting on diphenols ... |
antibacterial humoral response antimicrobial humoral immune response mediated by antimicrobial peptide arachidonic acid secretion defense response to Gram-positive bacterium fatty acid biosynthetic process innate immune response in mucosa lipid catabolic process phosphatidylcholine metabolic process phosphatidylglycero... | cell surface; extracellular space | bile acid binding calcium ion binding calcium-dependent phospholipase A2 activity phospholipid binding signaling receptor binding | Canis lupus familiaris | Autocatalytic cleavage Calcium Disulfide bond Hydrolase Lipid metabolism Metal-binding Phospholipid metabolism Reference proteome Secreted Signal Zymogen | MKFLVLAALL | MKFLVLAALLTVAAAEGGISPRAVWQFRNMIKCTIPESDPLKDYNDYGCYCGLGGSGTPVDELDKCCQTHDHCYSEAKKLDSCKFLLDNPYTKIYSYSCSGSEITCSSKNKDCQAFICNCDRSAAICFSKAPYNKEHKNLDTKKYC | antibacterial humoral response antimicrobial humoral immune response mediated by antimicrobial peptide arachidonic acid secretion defense response to Gram-positive bacterium fatty acid biosynthetic process innate immune response in mucosa lipid catabolic process phosphatidylcholine metabolic process phosphatidylglycero... |
adult heart development blastoderm segmentation cephalic furrow formation germ-band extension heart morphogenesis motor neuron axon guidance negative regulation of cardioblast cell fate specification negative regulation of transcription by RNA polymerase II periodic partitioning by pair rule gene positive regulation of... | nucleus | DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding | Drosophila melanogaster | 3D-structure Developmental protein DNA-binding Homeobox Nucleus Pair-rule protein Reference proteome Transcription Transcription regulation | MHGYRTYNME | MHGYRTYNMESHHAHHDASPVDQKPLVVDLLATQYGKPQTPPPSPNECLSSPDNSLNGSRGSEIPADPSVRRYRTAFTRDQLGRLEKEFYKENYVSRPRRCELAAQLNLPESTIKVWFQNRRMKDKRQRIAVAWPYAAVYSDPAFAASILQAAANSVGMPYPPYAPAAAAAAAAAAAVATNPMMATGMPPMGMPQMPTMQMPGHSGHAGHPSPYGQYRYTPYHIPARPAPPHPAGPHMHHPHMMGSSATGSSYSAGAAGLLGALPSATCYTGLGVGVPKTQTPPLDLQSSSSPHSSTLSLSPVGSDHAKVFDRSPVAQSA... | adult heart development blastoderm segmentation cephalic furrow formation germ-band extension heart morphogenesis motor neuron axon guidance negative regulation of cardioblast cell fate specification negative regulation of transcription by RNA polymerase II periodic partitioning by pair rule gene positive regulation of... |
lysosome localization microtubule cytoskeleton organization mitotic cell cycle | astral microtubule; centrosome; cytoplasm; microtubule; nucleus; perinuclear region of cytoplasm; spindle | GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton | Drosophila melanogaster | 3D-structure Acetylation Cytoplasm Cytoskeleton GTP-binding Hydrolase Magnesium Metal-binding Microtubule Nucleotide-binding Reference proteome | MRECISIHVG | MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTVGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYR... | lysosome localization microtubule cytoskeleton organization mitotic cell cycle astral microtubule; centrosome; cytoplasm; microtubule; nucleus; perinuclear region of cytoplasm; spindle GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton Drosophila melanogaster 3D-structure Acetylatio... |
microtubule cytoskeleton organization mitotic cell cycle unidimensional cell growth | cytoplasm; cytoplasmic microtubule; microtubule; spindle microtubule | GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton | Drosophila melanogaster | Acetylation Cytoplasm Cytoskeleton Direct protein sequencing GTP-binding Hydrolase Magnesium Metal-binding Microtubule Nucleotide-binding Reference proteome | MRECISVHIG | MRECISVHIGQAGVQIGNACWELYCLEHGIQPDGHMPSDKTVGGGDDSFSTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDVVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYMNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISVEKAYHEQLTVAEITNACFEPANQMVKCDPRRGKYMACCMLYR... | microtubule cytoskeleton organization mitotic cell cycle unidimensional cell growth cytoplasm; cytoplasmic microtubule; microtubule; spindle microtubule GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton Drosophila melanogaster Acetylation Cytoplasm Cytoskeleton Direct protein seque... |
microtubule cytoskeleton organization mitotic cell cycle sperm axoneme assembly spermatogenesis | cytoplasm; microtubule; perinuclear region of cytoplasm | GTP binding hydrolase activity metal ion binding myosin binding structural constituent of cytoskeleton | Drosophila melanogaster | Acetylation Cytoplasm Cytoskeleton GTP-binding Hydrolase Magnesium Metal-binding Microtubule Nucleotide-binding Reference proteome | MRECISIHVG | MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTVGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAVYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPVISAEKAYHEQLSVAEITNACFEPANQMVKVDPRHGKYMACCMLYR... | microtubule cytoskeleton organization mitotic cell cycle sperm axoneme assembly spermatogenesis cytoplasm; microtubule; perinuclear region of cytoplasm GTP binding hydrolase activity metal ion binding myosin binding structural constituent of cytoskeleton Drosophila melanogaster Acetylation Cytoplasm Cytoskeleton GTP-bi... |
central nervous system development embryo development ending in birth or egg hatching embryonic cleavage female pronucleus assembly microtubule cytoskeleton organization mitotic cell cycle mitotic spindle organization mRNA transport nuclear division peripheral nervous system development pronuclear migration sperm aster... | cortical microtubule; cytoplasm; microtubule; nucleus; perinuclear region of cytoplasm; plasma membrane | GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton | Drosophila melanogaster | Cytoplasm Cytoskeleton GTP-binding Hydrolase Magnesium Metal-binding Microtubule Nucleotide-binding Reference proteome | MREVVSIQIG | MREVVSIQIGQCGIQIGNACWELYLLEHGINLDGSLKTKEELTASGSSASVGHDTSANDARTFFTETGNGKQVPRSIFVDLEPTVIDDVRNGCMRELYHPEQLISGKEDAANNYARGRYSIGKEVIDRVTSRLQKIAEQCDSLQGFLIFHSLGGGTGSGFTSLLVERLSTDYSKKCKLDFAVYPSPKVSTAVVEPYNALLTTHSTMDHSDCVFMVDNEAIYDICNNSLGVDRPAYRNLNRLIAQIVSSTTASLRFSGSMNVDLNEFQTNLVPFPRIHFPLVAYAPLMSAERSAHEQHAITTLTNACFESSNMMVKCDPRA... | central nervous system development embryo development ending in birth or egg hatching embryonic cleavage female pronucleus assembly microtubule cytoskeleton organization mitotic cell cycle mitotic spindle organization mRNA transport nuclear division peripheral nervous system development pronuclear migration sperm aster... |
embryo development ending in birth or egg hatching lipid catabolic process regulation of embryonic development response to bacterium sex differentiation | extracellular region; extracellular space; P granule | serine hydrolase activity | Drosophila melanogaster | Phosphoprotein Reference proteome Secreted Signal Sulfation | MMSLRICLLA | MMSLRICLLATCLLVAAHASKDASNDRLKPTKWLTATELENVPSLNDITWERLENQPLEQGAKVIEKIYHVGQIKHDLTPSFVPSPSNVPVWIIKSNGQKVECKLNNYVETAKAQPGFGEDEVTIVLTGLPKTSPAQQKAMRRLIQAYVQKYNLQQLQKNAQEQQQQLKSSDYDYTSSEEAADQWKSAKAASGDLIIIDLGSTLTNFKRYAMLDVLNTGAMIGQTLIDLTNKGVPQEIIHLIGQGISAHVAGAAGNKYTAQTGHKLRRITGLDPAKVLSKRPQILGGLSRGDADFVDAIHTSTFAMGTPIRCGDVDFYPN... | embryo development ending in birth or egg hatching lipid catabolic process regulation of embryonic development response to bacterium sex differentiation extracellular region; extracellular space; P granule serine hydrolase activity Drosophila melanogaster Phosphoprotein Reference proteome Secreted Signal Sulfation MMSL... |
cobalamin transport | ATP-binding cassette (ABC) transporter complex; BtuCD complex; cobalamin transport complex; membrane; plasma membrane | ABC-type vitamin B12 transporter activity identical protein binding transmembrane transporter activity | Escherichia coli | 3D-structure Cell inner membrane Cell membrane Membrane Reference proteome Transmembrane Transmembrane helix Transport | MLTLARQQQR | MLTLARQQQRQNIRWLLCLSVLMLLALLLSLCAGEQWISPGDWFTPRGELFVWQIRLPRTLAVLLVGAALAISGAVMQALFENPLAEPGLLGVSNGAGVGLIAAVLLGQGQLPNWALGLCAIAGALIITLILLRFARRHLSTSRLLLAGVALGIICSALMTWAIYFSTSVDLRQLMYWMMGGFGGVDWRQSWLMLALIPVLLWICCQSRPMNMLALGEISARQLGLPLWFWRNVLVAATGWMVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLLPGCALAGASALLLADIVARLALAAAELPIGVVTATLGAPVFIWL... | cobalamin transport ATP-binding cassette (ABC) transporter complex; BtuCD complex; cobalamin transport complex; membrane; plasma membrane ABC-type vitamin B12 transporter activity identical protein binding transmembrane transporter activity Escherichia coli 3D-structure Cell inner membrane Cell membrane Membrane Refere... |
cobalamin transport | ATP-binding cassette (ABC) transporter complex; BtuCD complex; cobalamin transport complex; extrinsic component of membrane; membrane | ABC-type vitamin B12 transporter activity ATP binding ATP hydrolysis activity ATPase-coupled transmembrane transporter activity | Escherichia coli | 3D-structure ATP-binding Cell inner membrane Cell membrane Membrane Nucleotide-binding Reference proteome Translocase Transport | MSIVMQLQDV | MSIVMQLQDVAESTRLGPLSGEVRAGEILHLVGPNGAGKSTLLARMAGMTSGKGSIQFAGQPLEAWSATKLALHRAYLSQQQTPPFATPVWHYLTLHQHDKTRTELLNDVAGALALDDKLGRSTNQLSGGEWQRVRLAAVVLQITPQANPAGQLLLLDEPMNSLDVAQQSALDKILSALCQQGLAIVMSSHDLNHTLRHAHRAWLLKGGKMLASGRREEVLTPPNLAQAYGMNFRRLDIEGHRMLISTI | cobalamin transport ATP-binding cassette (ABC) transporter complex; BtuCD complex; cobalamin transport complex; extrinsic component of membrane; membrane ABC-type vitamin B12 transporter activity ATP binding ATP hydrolysis activity ATPase-coupled transmembrane transporter activity Escherichia coli 3D-structure ATP-bind... |
DNA topological change | chromosome; cytosol | DNA binding DNA topoisomerase activity DNA topoisomerase type I (single strand cut, ATP-independent) activity metal ion binding | Escherichia coli | 3D-structure DNA-binding Isomerase Magnesium Metal-binding Reference proteome Repeat Topoisomerase Zinc Zinc-finger | MGKALVIVES | MGKALVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWEAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFNKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEVDASTTTPSGEALALQVTHQNDKPFRPVNKEQTQAAVSLLEKARYSVLEREDKPTTSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYM... | DNA topological change chromosome; cytosol DNA binding DNA topoisomerase activity DNA topoisomerase type I (single strand cut, ATP-independent) activity metal ion binding Escherichia coli 3D-structure DNA-binding Isomerase Magnesium Metal-binding Reference proteome Repeat Topoisomerase Zinc Zinc-finger MGKALVIVES MGKAL... |
protein phosphorylation ribosomal small subunit assembly ribosomal small subunit biogenesis | cytoplasm; cytosol; plasma membrane | GTP binding GTPase activity guanosine tetraphosphate binding ribosomal small subunit binding RNA binding rRNA binding small ribosomal subunit rRNA binding | Escherichia coli | 3D-structure Cell inner membrane Cell membrane Cytoplasm Direct protein sequencing GTP-binding Membrane Nucleotide-binding Phosphoprotein Reference proteome Ribosome biogenesis RNA-binding rRNA-binding | MSIDKSYCGF | MSIDKSYCGFIAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTRHRIVGIHTEGAYQAIYVDTPGLHMEEKRAINRLMNKAASSSIGDVELVIFVVEGTRWTPDDEMVLNKLREGKAPVILAVNKVDNVQEKADLLPHLQFLASQMNFLDIVPISAETGLNVDTIAAIVRKHLPEATHHFPEDYITDRSQRFMASEIIREKLMRFLGAELPYSVTVEIERFVSNERGGYDINGLILVEREGQKKMVIGNKGAKIKTIGIEARKDMQEMFEAPVHLELWVKVKSGWADDERALRSLGYVDDL | protein phosphorylation ribosomal small subunit assembly ribosomal small subunit biogenesis cytoplasm; cytosol; plasma membrane GTP binding GTPase activity guanosine tetraphosphate binding ribosomal small subunit binding RNA binding rRNA binding small ribosomal subunit rRNA binding Escherichia coli 3D-structure Cell in... |
cyclic nucleotide catabolic process | cytoplasm; melanosome; membrane | 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity RNA binding | Bos taurus | Direct protein sequencing Hydrolase Lipoprotein Membrane Methylation Phosphoprotein Prenylation Reference proteome RNA-binding | MSSSGAKDKP | MSSSGAKDKPELQFPFLQDEETVATLQECKTLFILRGLPGSGKSTLARFIVDKYRDGTKMVSADSYKITPGARGSFSEEYKQLDEDLAACCRRDFRVLVLDDTNHERERLEQLFELADQYQYQVVLVEPKTAWRLDCAQLKEKNQWQLSADDLKKLKPGLEKDFLPLYFGWFLTKKSSAALWKTGQTFLEELGNHKAFKKELRHFVSGDEPREKIELVTYFGKRPPGVLHCTTKFCDYGKAAGAEEYAQQDVVKKSYCKAFTLTISALFVTPKTTGARVELSEQQLALWPNDVDKLSPSDNLPRGSRAHITLGCAGDVEA... | cyclic nucleotide catabolic process cytoplasm; melanosome; membrane 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity RNA binding Bos taurus Direct protein sequencing Hydrolase Lipoprotein Membrane Methylation Phosphoprotein Prenylation Reference proteome RNA-binding MSSSGAKDKP MSSSGAKDKPELQFPFLQDEETVATLQECKTLFILRG... |
gap junction-mediated intercellular transport lens development in camera-type eye positive regulation of cell adhesion protein homotetramerization visual perception water transport | apical plasma membrane; endoplasmic reticulum; gap junction; plasma membrane | calmodulin binding structural constituent of eye lens water channel activity | Bos taurus | 3D-structure Cell junction Cell membrane Direct protein sequencing Eye lens protein Gap junction Lipoprotein Membrane Phosphoprotein Reference proteome Repeat Transmembrane Transmembrane helix Transport | MWELRSASFW | MWELRSASFWRAICAEFFASLFYVFFGLGASLRWAPGPLHVLQVALAFGLALATLVQAVGHISGAHVNPAVTFAFLVGSQMSLLRAICYMVAQLLGAVAGAAVLYSVTPPAVRGNLALNTLHPGVSVGQATIVEIFLTLQFVLCIFATYDERRNGRLGSVALAVGFSLTLGHLFGMYYTGAGMNPARSFAPAILTRNFTNHWVYWVGPVIGAGLGSLLYDFLLFPRLKSVSERLSILKGSRPSESNGQPEVTGEPVELKTQAL | gap junction-mediated intercellular transport lens development in camera-type eye positive regulation of cell adhesion protein homotetramerization visual perception water transport apical plasma membrane; endoplasmic reticulum; gap junction; plasma membrane calmodulin binding structural constituent of eye lens water ch... |
L-ascorbic acid biosynthetic process | cytoplasm | oxidoreductase activity | Corynebacterium sp. | 3D-structure Ascorbate biosynthesis Cytoplasm Direct protein sequencing NADP Oxidoreductase | MTVPSIVLND | MTVPSIVLNDGNSIPQLGYGVFKVPPADTQRAVEEALEVGYRHIDTAAIYGNEEGVGAAIAASGIARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWPTPAADNYVHAWEKMIELRAAGLTRSIGVSNHLVPHLERIVAATGVVPAVNQIELHPAYQQREITDWAAAHDVKIESWGPLGQGKYDLFGAEPVTAAAAAHGKTPAQAVLRWHLQKGFVVFPKSVRRERLEENLDVFDFDLTDTEIAAIDAMDPGDGSGRVSAHPDEVD | L-ascorbic acid biosynthetic process cytoplasm oxidoreductase activity Corynebacterium sp. 3D-structure Ascorbate biosynthesis Cytoplasm Direct protein sequencing NADP Oxidoreductase MTVPSIVLND MTVPSIVLNDGNSIPQLGYGVFKVPPADTQRAVEEALEVGYRHIDTAAIYGNEEGVGAAIAASGIARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWPTPAADNYVHAWEKMIE... |
positive regulation of formation of translation preinitiation complex spliceosomal complex disassembly translational initiation | cytoplasm; cytoplasmic stress granule; nucleus | ATP binding ATP hydrolysis activity eukaryotic initiation factor 4G binding mRNA binding RNA binding RNA helicase activity RNA strand annealing activity translation initiation factor activity | Saccharomyces cerevisiae | 3D-structure Acetylation ATP-binding Cytoplasm Helicase Hydrolase Initiation factor Isopeptide bond Methylation Nucleotide-binding Phosphoprotein Protein biosynthesis Reference proteome RNA-binding Ubl conjugation | MAELSEQVQN | MAELSEQVQNLSINDNNENGYVPPHLRGKPRSARNNSSNYNNNNGGYNGGRGGGSFFSNNRRGGYGNGGFFGGNNGGSRSNGRSGGRWIDGKHVPAPRNEKAEIAIFGVPEDPNFQSSGINFDNYDDIPVDASGKDVPEPITEFTSPPLDGLLLENIKLARFTKPTPVQKYSVPIVANGRDLMACAQTGSGKTGGFLFPVLSESFKTGPSPQPESQGSFYQRKAYPTAVIMAPTRELATQIFDEAKKFTYRSWVKACVVYGGSPIGNQLREIERGCDLLVATPGRLNDLLERGKISLANVKYLVLDEADRMLDMGFEPQI... | positive regulation of formation of translation preinitiation complex spliceosomal complex disassembly translational initiation cytoplasm; cytoplasmic stress granule; nucleus ATP binding ATP hydrolysis activity eukaryotic initiation factor 4G binding mRNA binding RNA binding RNA helicase activity RNA strand annealing a... |
cell division G2/M transition of mitotic cell cycle mitotic G2 cell size control checkpoint signaling mitotic intra-S DNA damage checkpoint signaling positive regulation of G2/M transition of mitotic cell cycle positive regulation of G2/MI transition of meiotic cell cycle regulation of cell cycle switching, mitotic to ... | cytoplasm; cytosol; nucleus | phosphoprotein phosphatase activity protein tyrosine phosphatase activity | Schizosaccharomyces pombe | Cell cycle Cell division Cytoplasm Hydrolase Mitosis Nucleus Phosphoprotein Protein phosphatase Reference proteome | MDSPLSSLSF | MDSPLSSLSFTNTLSGKRNVLRPAARELKLMSDRNANQELDFFFPKSKHIASTLVDPFGKTCSTASPASSLAADMSMNMHIDESPALPTPRRTLFRSLSCTVETPLANKTIVSPLPESPSNDALTESYFFRQPASKYSITQDSPRVSSTIAYSFKPKASIALNTTKSEATRSSLSSSSFDSYLRPNVSRSRSSGNAPPFLRSRSSSSYSINKKKGTSGGQATRHLTYALSRTCSQSSNTTSLLESCLTDDTDDFELMSDHEDTFTMGKVADLPESSVELVEDAASIQRPNSDFGACNDNSLDDLFQASPIKPIDMLPKIN... | cell division G2/M transition of mitotic cell cycle mitotic G2 cell size control checkpoint signaling mitotic intra-S DNA damage checkpoint signaling positive regulation of G2/M transition of mitotic cell cycle positive regulation of G2/MI transition of meiotic cell cycle regulation of cell cycle switching, mitotic to ... |
complement activation complement activation, classical pathway innate immune response positive regulation of apoptotic cell clearance proteolysis response to bacterium response to lipopolysaccharide response to nutrient response to thyroid hormone | classical-complement-pathway C3/C5 convertase complex; extracellular exosome; extracellular region; extracellular space | metal ion binding serine-type endopeptidase activity | Homo sapiens | 3D-structure Age-related macular degeneration Alternative splicing Complement pathway Direct protein sequencing Disease variant Disulfide bond Glycoprotein Hydrolase Immunity Innate immunity Metal-binding Protease Reference proteome Repeat Secreted Serine protease Signal Sushi | MGPLMVLFCL | MGPLMVLFCLLFLYPGLADSAPSCPQNVNISGGTFTLSHGWAPGSLLTYSCPQGLYPSPASRLCKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGATNPTQKTKESLGRKIQIQRSGHLNLYLLLDCSQSVSENDFLIFKESASLMVDRIFSFEINVSVAIITFASEPKVLMSVLNDNSRDMTEVI... | complement activation complement activation, classical pathway innate immune response positive regulation of apoptotic cell clearance proteolysis response to bacterium response to lipopolysaccharide response to nutrient response to thyroid hormone classical-complement-pathway C3/C5 convertase complex; extracellular exo... |
adult locomotory behavior cardiac muscle contraction cellular response to amyloid-beta cellular response to retinoic acid cellular response to thyroid hormone stimulus cerebral cortex development intracellular potassium ion homeostasis intracellular sodium ion homeostasis ionotropic glutamate receptor signaling pathway... | axon; calyx of Held; cytoplasm; dendritic spine head; dendritic spine neck; endoplasmic reticulum; Golgi apparatus; membrane; myelin sheath; neuron to neuron synapse; neuronal cell body; nucleus; organelle membrane; photoreceptor inner segment; plasma membrane; postsynapse; presynaptic membrane; sarcolemma; sodium:pota... | amyloid-beta binding ATP binding ATP hydrolysis activity D1 dopamine receptor binding heparan sulfate proteoglycan binding metal ion binding P-type sodium:potassium-exchanging transporter activity P-type sodium:potassium-exchanging transporter activity involved in regulation of cardiac muscle cell membrane potential pr... | Rattus norvegicus | ATP-binding Cell membrane Direct protein sequencing Ion transport Magnesium Membrane Metal-binding Nucleotide-binding Phosphoprotein Potassium Potassium transport Reference proteome Sodium Sodium transport Sodium/potassium transport Translocase Transmembrane Transmembrane helix Transport | MGDKKDDKSS | MGDKKDDKSSPKKSKAKERRDLDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSLILGYTWLEAVIFLIGIIVA... | adult locomotory behavior cardiac muscle contraction cellular response to amyloid-beta cellular response to retinoic acid cellular response to thyroid hormone stimulus cerebral cortex development intracellular potassium ion homeostasis intracellular sodium ion homeostasis ionotropic glutamate receptor signaling pathway... |
chromatin organization double-strand break repair via nonhomologous end joining establishment of protein-containing complex localization to telomere heterochromatin formation negative regulation of DNA amplification negative regulation of DNA recombination negative regulation of DNA replication rDNA heterochromatin for... | chromatin silencing complex; chromosome, telomeric region; heterochromatin; nucleolus; nucleus; RENT complex | metal ion binding NAD+ binding NAD-dependent histone deacetylase activity NAD-dependent histone H3K14 deacetylase activity NAD-dependent histone H3K9 deacetylase activity NAD-dependent histone H4K16 deacetylase activity transferase activity | Saccharomyces cerevisiae | 3D-structure Chromatin regulator DNA damage DNA repair Metal-binding NAD Nucleus Reference proteome Repressor Transcription Transcription regulation Transferase Zinc | MTIPHMKYAV | MTIPHMKYAVSKTSENKVSNTVSPTQDKDAIRKQPDDIINNDEPSHKKIKVAQPDSLRETNTTDPLGHTKAALGEVASMELKPTNDMDPLAVSAASVVSMSNDVLKPETPKGPIIISKNPSNGIFYGPSFTKRESLNARMFLKYYGAHKFLDTYLPEDLNSLYIYYLIKLLGFEVKDQALIGTINSIVHINSQERVQDLGSAISVTNVEDPLAKKQTVRLIKDLQRAINKVLCTRLRLSNFFTIDHFIQKLHTARKILVLTGAGVSTSLGIPDFRSSEGFYSKIKHLGLDDPQDVFNYNIFMHDPSVFYNIANMVLPPEK... | chromatin organization double-strand break repair via nonhomologous end joining establishment of protein-containing complex localization to telomere heterochromatin formation negative regulation of DNA amplification negative regulation of DNA recombination negative regulation of DNA replication rDNA heterochromatin for... |
double-strand break repair via nonhomologous end joining establishment of protein-containing complex localization to telomere heterochromatin formation nuclear-transcribed mRNA catabolic process, non-stop decay silent mating-type cassette heterochromatin formation subtelomeric heterochromatin formation telomere tetheri... | chromatin silencing complex; chromosome, telomeric region; heterochromatin; mitochondrion; nucleolus | chromatin binding double-stranded DNA binding identical protein binding nucleic acid binding nucleosome binding single-stranded DNA binding | Saccharomyces cerevisiae | 3D-structure Acetylation DNA-binding Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation | MAKTLKDLDG | MAKTLKDLDGWQVIITDDQGRVIDDNNRRRSRKRGGENVFLKRISDGLSFGKGESVIFNDNVTETYSVYLIHEIRLNTLNNVVEIWVFSYLRWFELKPKLYYEQFRPDLIKEDHPLEFYKDKFFNEVNKSELYLTAELSEIWLKDFIAVGQILPESQWNDSSIDKIEDRDFLVRYACEPTAEKFVPIDIFQIIRRVKEMEPKQSDEYLKRVSVPVSGQKTNRQVMHKMGVERSSKRLAKKPSMKKIKIEPSADDDVNNGNIPSQRGTSTTHGSISPQEESVSPNISSASPSALTSPTDSSKILQKRSISKELIVSEEIPI... | double-strand break repair via nonhomologous end joining establishment of protein-containing complex localization to telomere heterochromatin formation nuclear-transcribed mRNA catabolic process, non-stop decay silent mating-type cassette heterochromatin formation subtelomeric heterochromatin formation telomere tetheri... |
axonogenesis positive regulation of fibroblast proliferation signal transduction | collagen-containing extracellular matrix; cytoplasm; cytoplasmic side of plasma membrane; cytosol; extracellular exosome; extracellular region; nuclear envelope; nucleus; perinuclear region of cytoplasm; plasma membrane; ruffle | calcium ion binding calcium-dependent protein binding monoatomic ion transmembrane transporter activity protein homodimerization activity S100 protein binding tropomyosin binding zinc ion binding | Homo sapiens | 3D-structure Acetylation Calcium Cell membrane Cytoplasm Direct protein sequencing Membrane Metal-binding Nucleus Phosphoprotein Reference proteome Repeat | MACPLDQAIG | MACPLDQAIGLLVAIFHKYSGREGDKHTLSKKELKELIQKELTIGSKLQDAEIARLMEDLDRNKDQEVNFQEYVTFLGALALIYNEALKG | axonogenesis positive regulation of fibroblast proliferation signal transduction collagen-containing extracellular matrix; cytoplasm; cytoplasmic side of plasma membrane; cytosol; extracellular exosome; extracellular region; nuclear envelope; nucleus; perinuclear region of cytoplasm; plasma membrane; ruffle calcium ion... |
cell division Golgi vesicle transport mRNA export from nucleus positive regulation of transcription by RNA polymerase II proteasome-mediated ubiquitin-dependent protein catabolic process spindle pole body duplication | cytoplasm; half bridge of spindle pole body; mitotic spindle pole body; nuclear envelope; transcription export complex 2 | calcium ion binding identical protein binding microtubule binding | Saccharomyces cerevisiae | 3D-structure Calcium Cell cycle Cell division Cytoplasm Cytoskeleton Metal-binding Mitosis Nucleus Phosphoprotein Reference proteome Repeat | MSKNRSSLQS | MSKNRSSLQSGPLNSELLEEQKQEIYEAFSLFDMNNDGFLDYHELKVAMKALGFELPKREILDLIDEYDSEGRHLMKYDDFYIVMGEKILKRDPLDEIKRAFQLFDDDHTGKISIKNLRRVAKELGETLTDEELRAMIEEFDLDGDGEINENEFIAICTDS | cell division Golgi vesicle transport mRNA export from nucleus positive regulation of transcription by RNA polymerase II proteasome-mediated ubiquitin-dependent protein catabolic process spindle pole body duplication cytoplasm; half bridge of spindle pole body; mitotic spindle pole body; nuclear envelope; transcription... |
biotin biosynthetic process biotin metabolic process protein modification process regulation of DNA-templated transcription | cytoplasm; transcription repressor complex | ATP binding biotin binding biotin- ligase activity DNA binding nucleic acid binding protein homodimerization activity transcription cis-regulatory region binding | Escherichia coli | 3D-structure ATP-binding Biotin DNA-binding Ligase Nucleotide-binding Reference proteome Repressor Transcription Transcription regulation | MKDNTVPLKL | MKDNTVPLKLIALLANGEFHSGEQLGETLGMSRAAINKHIQTLRDWGVDVFTVPGKGYSLPEPIQLLNAKQILGQLDGGSVAVLPVIDSTNQYLLDRIGELKSGDACIAEYQQAGRGRRGRKWFSPFGANLYLSMFWRLEQGPAAAIGLSLVIGIVMAEVLRKLGADKVRVKWPNDLYLQDRKLAGILVELTGKTGDAAQIVIGAGINMAMRRVEESVVNQGWITLQEAGINLDRNTLAAMLIRELRAALELFEQEGLAPYLSRWEKLDNFINRPVKLIIGDKEIFGISRGIDKQGALLLEQDGIIKPWMGGEISLRSAE... | biotin biosynthetic process biotin metabolic process protein modification process regulation of DNA-templated transcription cytoplasm; transcription repressor complex ATP binding biotin binding biotin- ligase activity DNA binding nucleic acid binding protein homodimerization activity transcription cis-regulatory region... |
DNA replication DNA-templated DNA replication | DNA polymerase III complex; DNA polymerase III, clamp loader complex; replisome | ATP binding ATP hydrolysis activity DNA binding DNA polymerase processivity factor activity DNA-directed DNA polymerase activity identical protein binding ribonucleoside triphosphate phosphatase activity | Escherichia coli | 3D-structure ATP-binding Direct protein sequencing DNA replication DNA-directed DNA polymerase Nucleotide-binding Nucleotidyltransferase Reference proteome Ribosomal frameshifting Transferase | MSYQVLARKW | MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRELARTI... | DNA replication DNA-templated DNA replication DNA polymerase III complex; DNA polymerase III, clamp loader complex; replisome ATP binding ATP hydrolysis activity DNA binding DNA polymerase processivity factor activity DNA-directed DNA polymerase activity identical protein binding ribonucleoside triphosphate phosphatase... |
cell redox homeostasis cellular response to oxidative stress glutathione metabolic process | cytosol; membrane | FAD binding flavin adenine dinucleotide binding glutathione-disulfide reductase (NADP) activity NADP binding | Escherichia coli | 3D-structure Cytoplasm Disulfide bond FAD Flavoprotein NADP Oxidoreductase Redox-active center Reference proteome | MTKHYDYIAI | MTKHYDYIAIGGGSGGIASINRAAMYGQKCALIEAKELGGTCVNVGCVPKKVMWHAAQIREAIHMYGPDYGFDTTINKFNWETLIASRTAYIDRIHTSYENVLGKNNVDVIKGFARFVDAKTLEVNGETITADHILIATGGRPSHPDIPGVEYGIDSDGFFALPALPERVAVVGAGYIAVELAGVINGLGAKTHLFVRKHAPLRSFDPMISETLVEVMNAEGPQLHTNAIPKAVVKNTDGSLTLELEDGRSETVDCLIWAIGREPANDNINLEAAGVKTNEKGYIVVDKYQNTNIEGIYAVGDNTGAVELTPVAVAAGRR... | cell redox homeostasis cellular response to oxidative stress glutathione metabolic process cytosol; membrane FAD binding flavin adenine dinucleotide binding glutathione-disulfide reductase (NADP) activity NADP binding Escherichia coli 3D-structure Cytoplasm Disulfide bond FAD Flavoprotein NADP Oxidoreductase Redox-acti... |
L-cysteine catabolic process to pyruvate methionine biosynthetic process protein homotetramerization transsulfuration | cytoplasm; protein-containing complex | alanine racemase activity cystathionine beta-lyase activity cysteine-S-conjugate beta-lyase activity identical protein binding L-cysteine desulfhydrase activity pyridoxal phosphate binding | Escherichia coli | 3D-structure Amino-acid biosynthesis Cytoplasm Direct protein sequencing Lyase Methionine biosynthesis Pyridoxal phosphate Reference proteome | MADKKLDTQL | MADKKLDTQLVNAGRSKKYTLGAVNSVIQRASSLVFDSVEAKKHATRNRANGELFYGRRGTLTHFSLQQAMCELEGGAGCVLFPCGAAAVANSILAFIEQGDHVLMTNTAYEPSQDFCSKILSKLGVTTSWFDPLIGADIVKHLQPNTKIVFLESPGSITMEVHDVPAIVAAVRSVVPDAIIMIDNTWAAGVLFKALDFGIDVSIQAATKYLVGHSDAMIGTAVCNARCWEQLRENAYLMGQMVDADTAYITSRGLRTLGVRLRQHHESSLKVAEWLAEHPQVARVNHPALPGSKGHEFWKRDFTGSSGLFSFVLKKKLN... | L-cysteine catabolic process to pyruvate methionine biosynthetic process protein homotetramerization transsulfuration cytoplasm; protein-containing complex alanine racemase activity cystathionine beta-lyase activity cysteine-S-conjugate beta-lyase activity identical protein binding L-cysteine desulfhydrase activity pyr... |
DNA modification mismatch repair regulation of DNA recombination | cytoplasm; mismatch repair complex | DNA binding endonuclease activity T/G mismatch-specific endonuclease activity | Escherichia coli | 3D-structure Cytoplasm Direct protein sequencing DNA damage DNA repair Endonuclease Hydrolase Nuclease Reference proteome | MSQPRPLLSP | MSQPRPLLSPPETEEQLLAQAQQLSGYTLGELAALVGLVTPENLKRDKGWIGVLLEIWLGASAGSKPEQDFAALGVELKTIPVDSLGRPLETTFVCVAPLTGNSGVTWETSHVRHKLKRVLWIPVEGERSIPLAQRRVGSPLLWSPNEEEDRQLREDWEELMDMIVLGQVERITARHGEYLQIRPKAANAKALTEAIGARGERILTLPRGFYLKKNFTSALLARHFLIQ | DNA modification mismatch repair regulation of DNA recombination cytoplasm; mismatch repair complex DNA binding endonuclease activity T/G mismatch-specific endonuclease activity Escherichia coli 3D-structure Cytoplasm Direct protein sequencing DNA damage DNA repair Endonuclease Hydrolase Nuclease Reference proteome MSQ... |
cholesterol efflux cholesterol homeostasis cholesterol metabolic process high-density lipoprotein particle remodeling hydrogen peroxide catabolic process innate immune response in mucosa leukocyte cell-cell adhesion lipid catabolic process lipid homeostasis lipid transport lipoprotein metabolic process negative regulat... | cell surface; chylomicron; cytosol; extracellular region; extracellular space; high-density lipoprotein particle; synapse; very-low-density lipoprotein particle | antioxidant activity cholesterol transfer activity copper ion binding identical protein binding lipid binding phosphatidylcholine binding phosphatidylcholine-sterol O-acyltransferase activator activity protein homodimerization activity | Mus musculus | Chylomicron Direct protein sequencing HDL Lipid transport Reference proteome Repeat Secreted Signal Transport | MFLKAAVLTL | MFLKAAVLTLALVAITGTRAEVTSDQVANVVWDYFTQLSNNAKEAVEQFQKTDVTQQLSTLFQDKLGDASTYADGVHNKLVPFVVQLSGHLAQETERVKEEIKKELEDLRDRMMPHANKVTQTFGENMQKLQEHLKPYAVDLQDQINTQTQEMKLQLTPYIQRMQTTIKENVDNLHTSMMPLATNLKDKFNRNMEELKGHLTPRANELKATIDQNLEDLRRSLAPLTVGVQEKLNHQMEGLAFQMKKNAEELQTKVSAKIDQLQKNLAPLVEDVQSKVKGNTEGLQKSLEDLNRQLEQQVEEFRRTVEPMGEMFNKALVQ... | cholesterol efflux cholesterol homeostasis cholesterol metabolic process high-density lipoprotein particle remodeling hydrogen peroxide catabolic process innate immune response in mucosa leukocyte cell-cell adhesion lipid catabolic process lipid homeostasis lipid transport lipoprotein metabolic process negative regulat... |
apoptotic process cell surface receptor signaling pathway cell-cell adhesion heterotypic cell-cell adhesion membrane raft polarization natural killer cell activation natural killer cell mediated cytotoxicity positive regulation of interleukin-8 production positive regulation of myeloid dendritic cell activation positiv... | cell surface; cell-cell junction; cytoplasmic side of plasma membrane; external side of plasma membrane; extracellular region; Golgi apparatus; nucleoplasm; plasma membrane; protein-containing complex | identical protein binding protein self-association receptor tyrosine kinase binding signaling receptor activity signaling receptor binding | Homo sapiens | 3D-structure Cell adhesion Cell membrane Disulfide bond Glycoprotein Immunoglobulin domain Membrane Reference proteome Repeat Signal Transmembrane Transmembrane helix | MSFPCKFVAS | MSFPCKFVASFLLIFNVSSKGAVSKEITNALETWGALGQDINLDIPSFQMSDDIDDIKWEKTSDKKKIAQFRKEKETFKEKDTYKLFKNGTLKIKHLKTDDQDIYKVSIYDTKGKNVLEKIFDLKIQERVSKPKISWTCINTTLTCEVMNGTDPELNLYQDGKHLKLSQRVITHKWTTSLSAKFKCTAGNKVSKESSVEPVSCPEKGLDIYLIIGICGGGSLLMVFVALLVFYITKRKKQRSRRNDEELETRAHRVATEERGRKPHQIPASTPQNPATSQHPPPPPGHRSQAPSHRPPPPGHRVQHQPQKRPPAPSGTQV... | apoptotic process cell surface receptor signaling pathway cell-cell adhesion heterotypic cell-cell adhesion membrane raft polarization natural killer cell activation natural killer cell mediated cytotoxicity positive regulation of interleukin-8 production positive regulation of myeloid dendritic cell activation positiv... |
behavioral fear response cellular response to dexamethasone stimulus G1/S transition of mitotic cell cycle mRNA export from nucleus negative regulation of neuron differentiation negative regulation of translation neuron differentiation positive regulation of mitotic cell cycle regulation of translation regulation of tr... | chromatoid body; cytoplasm; cytoplasmic ribonucleoprotein granule; cytoplasmic stress granule; cytosol; eukaryotic translation initiation factor 4F complex; extracellular exosome; glutamatergic synapse; mRNA cap binding complex; nuclear speck; nucleus; P-body; perinuclear region of cytoplasm; postsynapse; RISC complex | DNA-binding transcription factor binding enzyme binding eukaryotic initiation factor 4G binding mRNA cap binding RNA 7-methylguanosine cap binding RNA binding RNA cap binding translation initiation factor activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Autism Autism spectrum disorder Chromosomal rearrangement Cytoplasm Direct protein sequencing Host-virus interaction Initiation factor mRNA transport Nucleus Phosphoprotein Protein biosynthesis Reference proteome RNA-binding Translation regulation Transport | MATVEPETTP | MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV | behavioral fear response cellular response to dexamethasone stimulus G1/S transition of mitotic cell cycle mRNA export from nucleus negative regulation of neuron differentiation negative regulation of translation neuron differentiation positive regulation of mitotic cell cycle regulation of translation regulation of tr... |
apoptotic process heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules homophilic cell adhesion via plasma membrane adhesion molecules homotypic cell-cell adhesion negative regulation of anoikis negative regulation of apoptotic process negative regulation of myotube differentiation | apical plasma membrane; basolateral plasma membrane; cell surface; extracellular exosome; extracellular region; membrane; plasma membrane; side of membrane | GPI anchor binding identical protein binding protein homodimerization activity | Homo sapiens | 3D-structure Alternative splicing Apoptosis Cell adhesion Cell membrane Disulfide bond Glycoprotein GPI-anchor Immunoglobulin domain Lipoprotein Membrane Oncogene Reference proteome Repeat Signal | MESPSAPPHR | MESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQHLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFYTLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQAHNSDTGLNRTTVTTITVYA... | apoptotic process heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules homophilic cell adhesion via plasma membrane adhesion molecules homotypic cell-cell adhesion negative regulation of anoikis negative regulation of apoptotic process negative regulation of myotube differentiation apical plasma ... |
phosphocreatine biosynthetic process phosphorylation | cytosol; extracellular space | ATP binding creatine kinase activity | Homo sapiens | 3D-structure ATP-binding Cytoplasm Direct protein sequencing Kinase Nucleotide-binding Phosphoprotein Reference proteome Transferase | MPFGNTHNKF | MPFGNTHNKFKLNYKPEEEYPDLSKHNNHMAKVLTLELYKKLRDKETPSGFTVDDVIQTGVDNPGHPFIMTVGCVAGDEESYEVFKELFDPIISDRHGGYKPTDKHKTDLNHENLKGGDDLDPNYVLSSRVRTGRSIKGYTLPPHCSRGERRAVEKLSVEALNSLTGEFKGKYYPLKSMTEKEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKSFLVWVNEEDHLRVISMEKGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNQHLGYVLTCPSNLGTGLRGGVHVKLAHLSKHPKFEEILTRLRLQKR... | phosphocreatine biosynthetic process phosphorylation cytosol; extracellular space ATP binding creatine kinase activity Homo sapiens 3D-structure ATP-binding Cytoplasm Direct protein sequencing Kinase Nucleotide-binding Phosphoprotein Reference proteome Transferase MPFGNTHNKF MPFGNTHNKFKLNYKPEEEYPDLSKHNNHMAKVLTLELYKKLRD... |
canonical glycolysis gluconeogenesis glycolytic process negative regulation of cell growth negative regulation of DNA-templated transcription negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway negative regulation of transcription by RNA polymerase II positive regulation of ATP biosynthetic pro... | cell cortex; cell surface; cytoplasm; cytosol; extracellular exosome; extracellular space; M band; membrane; nuclear outer membrane; nucleus; phosphopyruvate hydratase complex; plasma membrane | cadherin binding DNA-binding transcription repressor activity, RNA polymerase II-specific GTPase binding magnesium ion binding phosphopyruvate hydratase activity protein homodimerization activity RNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription corepressor activi... | Homo sapiens | 3D-structure Acetylation Alternative initiation Cell membrane Cytoplasm Direct protein sequencing DNA-binding Glycolysis Hydroxylation Isopeptide bond Lyase Magnesium Membrane Metal-binding Nucleus Phosphoprotein Plasminogen activation Reference proteome Repressor Transcription Transcription regulation Ubl conjugation | MSILKIHARE | MSILKIHAREIFDSRGNPTVEVDLFTSKGLFRAAVPSGASTGIYEALELRDNDKTRYMGKGVSKAVEHINKTIAPALVSKKLNVTEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGNSEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAANFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEGLELLKTAIGKAGYTDKVVIGMDVAASEFFRSGKYDLDFKSPDDPSRYISPDQLADLYKSFIKDYPVVSIEDPFDQDDWGAWQKFTASAGIQVVGDDL... | canonical glycolysis gluconeogenesis glycolytic process negative regulation of cell growth negative regulation of DNA-templated transcription negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway negative regulation of transcription by RNA polymerase II positive regulation of ATP biosynthetic pro... |
B cell antigen processing and presentation Fc receptor-mediated immune complex endocytosis immune response macrophage activation positive regulation of humoral immune response mediated by circulating immunoglobulin positive regulation of killing of cells of another organism positive regulation of nitric-oxide synthase ... | external side of plasma membrane; extracellular exosome; plasma membrane | carbohydrate binding IgE binding integrin binding low-affinity IgE receptor activity metal ion binding | Homo sapiens | 3D-structure Calcium Cell membrane Direct protein sequencing Disulfide bond Glycoprotein IgE-binding protein Lectin Lipoprotein Membrane Metal-binding Palmitate Proteoglycan Receptor Reference proteome Repeat Secreted Signal-anchor Transmembrane Transmembrane helix | MEEGQYSEIE | MEEGQYSEIEELPRRRCCRRGTQIVLLGLVTAALWAGLLTLLLLWHWDTTQSLKQLEERAARNVSQVSKNLESHHGDQMAQKSQSTQISQELEELRAEQQRLKSQDLELSWNLNGLQADLSSFKSQELNERNEASDLLERLREEVTKLRMELQVSSGFVCNTCPEKWINFQRKCYYFGKGTKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGSWIGLRNLDLKGEFIWVDGSHVDYSNWAPGEPTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVCDRLATCTPPASEGSAESMGPDSRPDPDGRLPTPSAPLH... | B cell antigen processing and presentation Fc receptor-mediated immune complex endocytosis immune response macrophage activation positive regulation of humoral immune response mediated by circulating immunoglobulin positive regulation of killing of cells of another organism positive regulation of nitric-oxide synthase ... |
killing of cells of another organism toxin metabolic process | cytoplasm | ACP-dependent peptidyl-lysine N6-myristoyltransferase activity heme binding metal ion binding peptidyl-lysine N6-myristoyltransferase activity | Escherichia coli | Acyltransferase Cytolysis Cytoplasm Heme Hemolysis Iron Metal-binding Plasmid Transferase Virulence | MNINKPLEIL | MNINKPLEILGHVSWLWASSPLHRNWPVSLFAINVLPAIQANQYVLLTRDDYPVAYCSWANLSLENEIKYLNDVTSLVAEDWTSGDRKWFIDWIAPFGDNGALYKYMRKKFPDELFRAIRVDPKTHVGKVSEFHGGKIDKQLANKIFKQYHHELITEVKRKSDFNFSLTG | killing of cells of another organism toxin metabolic process cytoplasm ACP-dependent peptidyl-lysine N6-myristoyltransferase activity heme binding metal ion binding peptidyl-lysine N6-myristoyltransferase activity Escherichia coliAcyltransferase Cytolysis Cytoplasm Heme Hemolysis Iron Metal-binding Plasmid Transferase ... |
5-phosphoribose 1-diphosphate biosynthetic process glucose homeostasis glycogen catabolic process glycogen metabolic process necroptotic process response to bacterium | cytoplasm; cytosol; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; secretory granule lumen | AMP binding ATP binding bile acid binding glucose binding glycogen phosphorylase activity identical protein binding linear malto-oligosaccharide phosphorylase activity purine nucleobase binding pyridoxal phosphate binding SHG alpha-glucan phosphorylase activity vitamin binding | Homo sapiens | 3D-structure Acetylation Allosteric enzyme Alternative splicing Carbohydrate metabolism Cytoplasm Disease variant Glycogen metabolism Glycogen storage disease Glycosyltransferase Nucleotide-binding Phosphoprotein Pyridoxal phosphate Reference proteome Transferase | MAKPLTDQEK | MAKPLTDQEKRRQISIRGIVGVENVAELKKSFNRHLHFTLVKDRNVATTRDYYFALAHTVRDHLVGRWIRTQQHYYDKCPKRVYYLSLEFYMGRTLQNTMINLGLQNACDEAIYQLGLDIEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIRDGWQVEEADDWLRYGNPWEKSRPEFMLPVHFYGKVEHTNTGTKWIDTQVVLALPYDTPVPGYMNNTVNTMRLWSARAPNDFNLRDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKASKFGST... | 5-phosphoribose 1-diphosphate biosynthetic process glucose homeostasis glycogen catabolic process glycogen metabolic process necroptotic process response to bacterium cytoplasm; cytosol; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; secretory granule lumen AMP binding ATP binding bile acid ... |
glycogen catabolic process | cytoplasm | glycogen phosphorylase activity linear malto-oligosaccharide phosphorylase activity pyridoxal phosphate binding SHG alpha-glucan phosphorylase activity | Saccharomyces cerevisiae | 3D-structure Carbohydrate metabolism Cytoplasm Direct protein sequencing Glycogen metabolism Glycosyltransferase Phosphoprotein Pyridoxal phosphate Reference proteome Transferase | MPPASTSTTN | MPPASTSTTNDMITEEPTSPHQIPRLTRRLTGFLPQEIKSIDTMIPLKSRALWNKHQVKKFNKAEDFQDRFIDHVETTLARSLYNCDDMAAYEAASMSIRDNLVIDWNKTQQKFTTRDPKRVYYLSLEFLMGRALDNALINMKIEDPEDPAASKGKPREMIKGALDDLGFKLEDVLDQEPDAGLGNGGLGRLAACFVDSMATEGIPAWGYGLRYEYGIFAQKIIDGYQVETPDYWLNSGNPWEIERNEVQIPVTFYGYVDRPEGGKTTLSASQWIGGERVLAVAYDFPVPGFKTSNVNNLRLWQARPTTEFDFAKFNNGD... | glycogen catabolic process cytoplasm glycogen phosphorylase activity linear malto-oligosaccharide phosphorylase activity pyridoxal phosphate binding SHG alpha-glucan phosphorylase activity Saccharomyces cerevisiae 3D-structure Carbohydrate metabolism Cytoplasm Direct protein sequencing Glycogen metabolism Glycosyltran... |
carbohydrate metabolic process erythrocyte homeostasis gluconeogenesis glucose 6-phosphate metabolic process glucose homeostasis glycolytic process hemostasis humoral immune response in utero embryonic development learning or memory mesoderm formation negative regulation of neuron apoptotic process positive regulation ... | ciliary membrane; cytosol; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; membrane; secretory granule lumen | carbohydrate derivative binding cytokine activity glucose-6-phosphate isomerase activity growth factor activity monosaccharide binding ubiquitin protein ligase binding | Homo sapiens | 3D-structure Acetylation Alternative splicing Cytokine Cytoplasm Direct protein sequencing Disease variant Gluconeogenesis Glycolysis Growth factor Hereditary hemolytic anemia Hydroxylation Isomerase Phosphoprotein Reference proteome Secreted Ubl conjugation | MAALTRDPQF | MAALTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHFSLTLNTNHGHILVDYSKNLVTEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMPEVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPRVWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFLQAAKDPSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQLLSGAHWMDQHFRTTPLEKNAPVLL... | carbohydrate metabolic process erythrocyte homeostasis gluconeogenesis glucose 6-phosphate metabolic process glucose homeostasis glycolytic process hemostasis humoral immune response in utero embryonic development learning or memory mesoderm formation negative regulation of neuron apoptotic process positive regulation ... |
canonical glycolysis erythrocyte homeostasis gluconeogenesis glucose 6-phosphate metabolic process glucose homeostasis glycolytic process glycolytic process through glucose-6-phosphate in utero embryonic development learning or memory mesoderm formation negative regulation of neuron apoptotic process positive regulatio... | ciliary membrane; cytosol; extracellular space; myelin sheath; plasma membrane | carbohydrate derivative binding cytokine activity glucose-6-phosphate isomerase activity growth factor activity monosaccharide binding ubiquitin protein ligase binding | Mus musculus | 3D-structure Acetylation Cytokine Cytoplasm Direct protein sequencing Gluconeogenesis Glycolysis Growth factor Isomerase Phosphoprotein Reference proteome Secreted Ubl conjugation | MAALTRNPQF | MAALTRNPQFQKLLEWHRANSANLKLRELFEADPERFNNFSLNLNTNHGHILVDYSKNLVNKEVMQMLVELAKSRGVEAARDNMFSGSKINYTENRAVLHVALRNRSNTPIKVDGKDVMPEVNRVLDKMKSFCQRVRSGDWKGYTGKSITDIINIGIGGSDLGPLMVTEALKPYSKGGPRVWFVSNIDGTHIAKTLASLSPETSLFIIASKTFTTQETITNAETAKEWFLEAAKDPSAVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDHFEQLLSGAHWMDQHFLKTPLEKNAPVLL... | canonical glycolysis erythrocyte homeostasis gluconeogenesis glucose 6-phosphate metabolic process glucose homeostasis glycolytic process glycolytic process through glucose-6-phosphate in utero embryonic development learning or memory mesoderm formation negative regulation of neuron apoptotic process positive regulatio... |
base-excision repair base-excision repair, gap-filling DNA damage response DNA repair DNA-templated DNA replication double-strand break repair via nonhomologous end joining homeostasis of number of cells immunoglobulin heavy chain V-D-J recombination in utero embryonic development inflammatory response intrinsic apopto... | cytoplasm; microtubule; nucleoplasm; nucleus; protein-containing complex; spindle microtubule | 5'-deoxyribose-5-phosphate lyase activity class I DNA-(apurinic or apyrimidinic site) endonuclease activity damaged DNA binding DNA-(apurinic or apyrimidinic site) endonuclease activity DNA-directed DNA polymerase activity enzyme binding lyase activity metal ion binding microtubule binding | Homo sapiens | 3D-structure Acetylation Cytoplasm DNA damage DNA repair DNA replication DNA synthesis DNA-binding DNA-directed DNA polymerase Isopeptide bond Lyase Magnesium Metal-binding Methylation Nucleotidyltransferase Nucleus Reference proteome Sodium Transferase Ubl conjugation | MSKRKAPQET | MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIF... | base-excision repair base-excision repair, gap-filling DNA damage response DNA repair DNA-templated DNA replication double-strand break repair via nonhomologous end joining homeostasis of number of cells immunoglobulin heavy chain V-D-J recombination in utero embryonic development inflammatory response intrinsic apopto... |
defense response negative regulation of translation | endoplasmic reticulum | carbohydrate binding nucleotide binding rRNA N-glycosylase activity toxin activity | Ricinus communis | 3D-structure Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Lectin Nucleotide-binding Plant defense Protein synthesis inhibitor Repeat Signal Toxin | MYAVATWLCF | MYAVATWLCFGSTSGWSFTLEDNNIFPKQYPIINFTTADATVESYTNFIRAVRSHLTTGADVRHEIPVLPNRVGLPISQRFILVELSNHAELSVTLALDVTNAYVVGCRAGNSAYFFHPDNQEDAEAITHLFTDVQNSFTFAFGGNYDRLEQLGGLRENIELGTGPLEDAISALYYYSTCGTQIPTLARSFMVCIQMISEAARFQYIEGEMRTRIRYNRRSAPDPSVITLENSWGRLSTAIQESNQGAFASPIQLQRRNGSKFNVYDVSILIPIIALMVYRCAPPPSSQFSLLIRPVVPNFNADVCMDPEPIVRIVGRNG... | defense response negative regulation of translation endoplasmic reticulum carbohydrate binding nucleotide binding rRNA N-glycosylase activity toxin activity Ricinus communis 3D-structure Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Lectin Nucleotide-binding Plant defense Protein synthesis inhibitor R... |
actin filament organization muscle contraction | actin cytoskeleton; actin filament; cytoskeleton; cytosol; extracellular exosome; muscle thin filament tropomyosin; stress fiber | actin filament binding | Homo sapiens | 3D-structure Acetylation Actin-binding Alternative splicing Chromosomal rearrangement Coiled coil Cytoplasm Cytoskeleton Direct protein sequencing Disease variant Muscle protein Nemaline myopathy Phosphoprotein Proto-oncogene Reference proteome | MMEAIKKKMQ | MMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI | actin filament organization muscle contraction actin cytoskeleton; actin filament; cytoskeleton; cytosol; extracellular exosome; muscle thin filament tropomyosin; stress fiber actin filament binding Homo sapiens 3D-structure Acetylation Actin-binding Alternative splicing Chromosomal rearrangement Coiled coil Cytoplasm ... |
actin filament organization dendrite morphogenesis muscle contraction oogenesis pole plasm assembly pole plasm oskar mRNA localization regulation of lamellipodium assembly response to hyperoxia | actin filament; cytosol; investment cone; sarcomere | actin binding actin filament binding protein kinase binding | Drosophila melanogaster | Actin-binding Alternative splicing Coiled coil Cytoplasm Cytoskeleton Muscle protein Reference proteome | MDAIKKKMQA | MDAIKKKMQAMKVDKDGALERALVCEQEARDANTRAEKAEEEARQLQKKIQTVENELDQTQEALTLVTGKLEEKNKALQNKKKTTKMTTSIPQGTLLDVLKKKMRQTKEEMEKYKDECEEFHKRLQLEVVRREEAESEVAALNRRIQLLEEDLERSEERLGSATAKLSEASQAADESERARKILENRALADEERMDALENQLKEARFLAEEADKKYDEVARKLAMVEADLERAEERAEQGENKIVELEEELRVVGNNLKSLEVSEEKANQREEEYKNQIKTLNTRLKEAEARAEFAERSVQKLQKEVDRLEDDLVLEKER... | actin filament organization dendrite morphogenesis muscle contraction oogenesis pole plasm assembly pole plasm oskar mRNA localization regulation of lamellipodium assembly response to hyperoxia actin filament; cytosol; investment cone; sarcomere actin binding actin filament binding protein kinase binding Drosophila mel... |
acetaldehyde biosynthetic process animal organ regeneration behavioral response to ethanol ethanol catabolic process ethanol oxidation response to progesterone response to retinoic acid response to steroid hormone response to testosterone retinoic acid metabolic process retinoid metabolic process retinol metabolic proc... | cytosol; mitochondrion | alcohol dehydrogenase (NAD+) activity alcohol dehydrogenase activity, zinc-dependent ethanol binding identical protein binding NAD binding NAD-retinol dehydrogenase activity organic cyclic compound binding zinc ion binding | Rattus norvegicus | Acetylation Cytoplasm Metal-binding NAD Oxidoreductase Reference proteome Zinc | MSTAGKVIKC | MSTAGKVIKCKAAVLWEPHKPFTIEDIEVAPPKAHEVRIKMVATGVCRSDDHAVSGSLFTPLPAVLGHEGAGIVESIGEGVTCVKPGDKVIPLFSPQCGKCRICKHPESNLCCQTKNLTQPKGALLDGTSRFSCRGKPIHHFISTSTFSQYTVVDDIAVAKIDAAAPLDKVCLIGCGFSTGYGSAVQVAKVTPGSTCAVFGLGGVGLSVVIGCKTAGAAKIIAVDINKDKFAKAKELGATDCINPQDYTKPIQEVLQEMTDGGVDFSFEVIGRLDTMTSALLSCHSACGVSVIVGVPPSAQSLSVNPMSLLLGRTWKGAI... | acetaldehyde biosynthetic process animal organ regeneration behavioral response to ethanol ethanol catabolic process ethanol oxidation response to progesterone response to retinoic acid response to steroid hormone response to testosterone retinoic acid metabolic process retinoid metabolic process retinol metabolic proc... |
carbohydrate metabolic process chondroitin sulfate catabolic process glucuronoside catabolic process heparan sulfate proteoglycan catabolic process hyaluronan catabolic process | extracellular space; lysosomal lumen; lysosome | beta-glucuronidase activity carbohydrate binding hydrolase activity protein domain specific binding signaling receptor binding | Rattus norvegicus | Glycoprotein Glycosidase Hydrolase Lysosome Reference proteome Signal | MSPRRSVCWF | MSPRRSVCWFVLGQLLCSCAVALQGGMLFPKETPSRELKVLDGLWSFRADYSNNRLQGFEKQWYRQPLRESGPTLDMPVPSSFNDITQEAELRNFIGWVWYEREAVLPQRWTQDTDRRVVLRINSAHYYAVVWVNGIHVVEHEGGHLPFEADITKLVQSGPLTTFRVTIAINNTLTPYTLPPGTIVYKTDPSMYPKGYFVQDISFDFFNYAGLHRSVVLYTTPTTYIDDITVTTDVDRDVGLVNYWISVQGSDHFQLEVRLLDEDGKIVARGTGNEGQLKVPRAHLWWPYLMHEHPAYLYSLEVTMTTPESVSDFYTLPV... | carbohydrate metabolic process chondroitin sulfate catabolic process glucuronoside catabolic process heparan sulfate proteoglycan catabolic process hyaluronan catabolic process extracellular space; lysosomal lumen; lysosome beta-glucuronidase activity carbohydrate binding hydrolase activity protein domain specific bind... |
apoptotic process base-excision repair base-excision repair, gap-filling DNA damage response DNA replication double-strand break repair via nonhomologous end joining homeostasis of number of cells immunoglobulin heavy chain V-D-J recombination in utero embryonic development inflammatory response intrinsic apoptotic sig... | cytoplasm; microtubule; nucleus; protein-containing complex; spindle microtubule | 5'-deoxyribose-5-phosphate lyase activity class I DNA-(apurinic or apyrimidinic site) endonuclease activity damaged DNA binding DNA binding DNA-directed DNA polymerase activity enzyme binding lyase activity metal ion binding microtubule binding | Rattus norvegicus | 3D-structure Acetylation Cytoplasm Direct protein sequencing DNA damage DNA repair DNA replication DNA synthesis DNA-binding DNA-directed DNA polymerase Isopeptide bond Lyase Magnesium Metal-binding Methylation Nucleotidyltransferase Nucleus Potassium Reference proteome Sodium Transferase Ubl conjugation | MSKRKAPQET | MSKRKAPQETLNGGITDMLVELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVTGIGPSAARKLVDEGIKTLEDLRKNEDKLNHHQRIGLKYFEDFEKRIPREEMLQMQDIVLNEVKKLDPEYIATVCGSFRRGAESSGDMDVLLTHPNFTSESSKQPKLLHRVVEQLQKVRFITDTLSKGETKFMGVCQLPSENDENEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEQDIF... | apoptotic process base-excision repair base-excision repair, gap-filling DNA damage response DNA replication double-strand break repair via nonhomologous end joining homeostasis of number of cells immunoglobulin heavy chain V-D-J recombination in utero embryonic development inflammatory response intrinsic apoptotic sig... |
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