Biological Process
stringlengths
7
1.01k
Cellular Component
stringlengths
6
867
Molecular Function
stringlengths
11
871
Organism
stringlengths
8
73
Keywords
stringlengths
1
810
Sequence 10
stringlengths
5
10
Sequence
stringlengths
5
1.02k
Combined
stringlengths
136
3.91k
carbohydrate metabolic process
extracellular region
alpha-amylase activity cyclomaltodextrin glucanotransferase activity metal ion binding starch binding
Bacillus sp.
3D-structure Calcium Disulfide bond Glycosyltransferase Metal-binding Secreted Signal Transferase
MKRFMKLTAV
MKRFMKLTAVWTLWLSLTLGLLSPVHAAPDTSVSNKQNFSTDVIYQIFTDRFSDGNPANNPTGAAFDGSCTNLRLYCGGDWQGIINKINDGYLTGMGITAIWISQPVENIYSVINYSGVNNTAYHGYWARDFKKTNPAYGTMQDFKNLIDTAHAHNIKVIIDFAPNHTSPASSDDPSFAENGRLYDNGNLLGGYTNDTQNLFHHYGGTDFSTIENGIYKNLYDLADLNHNNSSVDVYLKDAIKMWLDLGVDGIRVDAVKHMPFGWQKSFMATINNYKPVFTFGEWFLGVNEISPEYHQFANESGMSLLDFRFAQKARQVFRDNTDNMYGLKAMLEGSEVDYAQVNDQVTFIDNHDMERFHTSNGDRRKLEQALAFTLTSRGVPAIYYGSEQYMSGGNDPDNRARLPSFSTTTTAYQVIQKLAPLRKSNPAIAYGSTHERWINNDVIIYERKFGNNVAVVAINRNMNTPASITGLVTSLRRASYNDVLGGILNGNTLTVGAGGAASNFTLAPGGTAVWQYTTDATTPIIGNVGPMMAKPGVTITIDGRGFGSGKGTVYFGTTAVTGADIVAWEDTQIQVKIPAVPGGIYDIRVANAAGAASNIYDNFEVLTGDQVTVRFVINNATTALGQNVFLTGNVSELGNWDPNNAIGPMYNQVVYQYPTWYYDVSVPAGQTIEFKFLKKQGSTVTWEGGANRTFTTPTSGTATVNVNWQP
carbohydrate metabolic process extracellular region alpha-amylase activity cyclomaltodextrin glucanotransferase activity metal ion binding starch binding Bacillus sp. 3D-structure Calcium Disulfide bond Glycosyltransferase Metal-binding Secreted Signal Transferase MKRFMKLTAV MKRFMKLTAVWTLWLSLTLGLLSPVHAAPDTSVSNKQNFSTDVIYQIFTDRFSDGNPANNPTGAAFDGSCTNLRLYCGGDWQGIINKINDGYLTGMGITAIWISQPVENIYSVINYSGVNNTAYHGYWARDFKKTNPAYGTMQDFKNLIDTAHAHNIKVIIDFAPNHTSPASSDDPSFAENGRLYDNGNLLGGYTNDTQNLFHHYGGTDFSTIENGIYKNLYDLADLNHNNSSVDVYLKDAIKMWLDLGVDGIRVDAVKHMPFGWQKSFMATINNYKPVFTFGEWFLGVNEISPEYHQFANESGMSLLDFRFAQKARQVFRDNTDNMYGLKAMLEGSEVDYAQVNDQVTFIDNHDMERFHTSNGDRRKLEQALAFTLTSRGVPAIYYGSEQYMSGGNDPDNRARLPSFSTTTTAYQVIQKLAPLRKSNPAIAYGSTHERWINNDVIIYERKFGNNVAVVAINRNMNTPASITGLVTSLRRASYNDVLGGILNGNTLTVGAGGAASNFTLAPGGTAVWQYTTDATTPIIGNVGPMMAKPGVTITIDGRGFGSGKGTVYFGTTAVTGADIVAWEDTQIQVKIPAVPGGIYDIRVANAAGAASNIYDNFEVLTGDQVTVRFVINNATTALGQNVFLTGNVSELGNWDPNNAIGPMYNQVVYQYPTWYYDVSVPAGQTIEFKFLKKQGSTVTWEGGANRTFTTPTSGTATVNVNWQP
proteolysis
extracellular region
serine-type endopeptidase activity toxin activity
Protobothrops flavoviridis
Blood coagulation cascade activating toxin Complement system impairing toxin Direct protein sequencing Disulfide bond Hemostasis impairing toxin Hydrolase Platelet aggregation inhibiting toxin Protease Secreted Serine protease Signal Toxin Zymogen
MVLIRVLANL
MVLIRVLANLLILQLSYAQKSSELVIGGDECNINEHPFLVALYDAWSGRFLCGGTLINPEWVLTAAHCDSKNFKMKLGAHSKKVLNEDEQIRNPKEKFICPNKKNDEVLDKDIMLIKLDSPVSYSEHIAPLSLPSSPPSVGSVCRIMGWGSITPVEETFPDVPHCANINLLDDVECKPGYPELLPEYRTLCAGVLQGGIDTCGFDSGTPLICNGQFQGIVSYGGHPCGQSRKPGIYTKVFDYNAWIQSIIAGNTAATCLP
proteolysis extracellular region serine-type endopeptidase activity toxin activity Protobothrops flavoviridis Blood coagulation cascade activating toxin Complement system impairing toxin Direct protein sequencing Disulfide bond Hemostasis impairing toxin Hydrolase Platelet aggregation inhibiting toxin Protease Secreted Serine protease Signal Toxin Zymogen MVLIRVLANL MVLIRVLANLLILQLSYAQKSSELVIGGDECNINEHPFLVALYDAWSGRFLCGGTLINPEWVLTAAHCDSKNFKMKLGAHSKKVLNEDEQIRNPKEKFICPNKKNDEVLDKDIMLIKLDSPVSYSEHIAPLSLPSSPPSVGSVCRIMGWGSITPVEETFPDVPHCANINLLDDVECKPGYPELLPEYRTLCAGVLQGGIDTCGFDSGTPLICNGQFQGIVSYGGHPCGQSRKPGIYTKVFDYNAWIQSIIAGNTAATCLP
adult feeding behavior G protein-coupled receptor signaling pathway multi-organism reproductive process negative regulation of female receptivity negative regulation of female receptivity, post-mating regulation of egg-laying behavior regulation of female receptivity, post-mating regulation of juvenile hormone biosynthetic process sexual reproduction
extracellular region; extracellular space
G protein-coupled receptor binding hormone activity
Drosophila melanogaster
3D-structure Behavior Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Hydroxylation Reference proteome Secreted Signal
MKTLALFLVL
MKTLALFLVLVCVLGLVQSWEWPWNRKPTKFPIPSPNPRDKWCRLNLGPAWGGRC
adult feeding behavior G protein-coupled receptor signaling pathway multi-organism reproductive process negative regulation of female receptivity negative regulation of female receptivity, post-mating regulation of egg-laying behavior regulation of female receptivity, post-mating regulation of juvenile hormone biosynthetic process sexual reproduction extracellular region; extracellular space G protein-coupled receptor binding hormone activity Drosophila melanogaster 3D-structure Behavior Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Hydroxylation Reference proteome Secreted Signal MKTLALFLVL MKTLALFLVLVCVLGLVQSWEWPWNRKPTKFPIPSPNPRDKWCRLNLGPAWGGRC
MAPK cascade phosphorylation
cytoplasm; cytosol; mitochondrion; plasma membrane
ATP binding MAP kinase kinase kinase activity metal ion binding protein serine kinase activity
Gallus gallus
Alternative splicing ATP-binding Cell membrane Cytoplasm Kinase Membrane Metal-binding Nucleotide-binding Phosphoprotein Proto-oncogene Reference proteome Serine/threonine-protein kinase Transferase Zinc Zinc-finger
MEHIQGAWKT
MEHIQGAWKTISNGFGLKDSVFDGPNCISPTIVQQFGYQRRASDDGKISDTSKTSNTIRVFLPNKQRTVVNVRNGMTLHDCLMKALKVRGLQPECCAVFRLVTEPKGKKVRLDWNTDAASLIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDWSNIRQLLLFPNSNISDSGVPALPPLTMRRMRESVSRIPVSSQHRYSTPHVFTFNTSNPSSEGTLSQRQRSTSTPNVHMVSTTMPVDSRIIEDAIRNHSESASPSALSGSPNNMSPTGWSQPKTPVPAQRERAPGTNTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDSNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCLKKVREERPLFPQILSSIELLQHSLPKINRSASEPSLHRASHTEDINSCTLTSTRLPVF
MAPK cascade phosphorylation cytoplasm; cytosol; mitochondrion; plasma membrane ATP binding MAP kinase kinase kinase activity metal ion binding protein serine kinase activity Gallus gallus Alternative splicing ATP-binding Cell membrane Cytoplasm Kinase Membrane Metal-binding Nucleotide-binding Phosphoprotein Proto-oncogene Reference proteome Serine/threonine-protein kinase Transferase Zinc Zinc-finger MEHIQGAWKT MEHIQGAWKTISNGFGLKDSVFDGPNCISPTIVQQFGYQRRASDDGKISDTSKTSNTIRVFLPNKQRTVVNVRNGMTLHDCLMKALKVRGLQPECCAVFRLVTEPKGKKVRLDWNTDAASLIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDWSNIRQLLLFPNSNISDSGVPALPPLTMRRMRESVSRIPVSSQHRYSTPHVFTFNTSNPSSEGTLSQRQRSTSTPNVHMVSTTMPVDSRIIEDAIRNHSESASPSALSGSPNNMSPTGWSQPKTPVPAQRERAPGTNTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDSNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCLKKVREERPLFPQILSSIELLQHSLPKINRSASEPSLHRASHTEDINSCTLTSTRLPVF
protein-containing complex assembly proton motive force-driven ATP synthesis
mitochondrial inner membrane; mitochondrial proton-transporting ATP synthase complex; mitochondrial proton-transporting ATP synthase complex, coupling factor F(o); mitochondrial proton-transporting ATP synthase, stator stalk; mitochondrion
proton transmembrane transporter activity
Saccharomyces cerevisiae
3D-structure CF(0) Direct protein sequencing Hydrogen ion transport Ion transport Membrane Mitochondrion Mitochondrion inner membrane Phosphoprotein Reference proteome Transit peptide Transport
MSMSMGVRGL
MSMSMGVRGLALRSVSKTLFSQGVRCPSMVIGARYMSSTPEKQTDPKAKANSIINAIPGNNILTKTGVLGTSAAAVIYAISNELYVINDESILLLTFLGFTGLVAKYLAPAYKDFADARMKKVSDVLNASRNKHVEAVKDRIDSVSQLQNVAETTKVLFDVSKETVELESEAFELKQKVELAHEAKAVLDSWVRYEASLRQLEQRQLAKSVISRVQSELGNPKFQEKVLQQSISEIEQLLSKLK
protein-containing complex assembly proton motive force-driven ATP synthesis mitochondrial inner membrane; mitochondrial proton-transporting ATP synthase complex; mitochondrial proton-transporting ATP synthase complex, coupling factor F(o); mitochondrial proton-transporting ATP synthase, stator stalk; mitochondrion proton transmembrane transporter activity Saccharomyces cerevisiae 3D-structure CF(0) Direct protein sequencing Hydrogen ion transport Ion transport Membrane Mitochondrion Mitochondrion inner membrane Phosphoprotein Reference proteome Transit peptide Transport MSMSMGVRGL MSMSMGVRGLALRSVSKTLFSQGVRCPSMVIGARYMSSTPEKQTDPKAKANSIINAIPGNNILTKTGVLGTSAAAVIYAISNELYVINDESILLLTFLGFTGLVAKYLAPAYKDFADARMKKVSDVLNASRNKHVEAVKDRIDSVSQLQNVAETTKVLFDVSKETVELESEAFELKQKVELAHEAKAVLDSWVRYEASLRQLEQRQLAKSVISRVQSELGNPKFQEKVLQQSISEIEQLLSKLK
aerobic respiration mitochondrial proton-transporting ATP synthase complex assembly proton motive force-driven ATP synthesis proton motive force-driven mitochondrial ATP synthesis proton transmembrane transport
mitochondrial envelope; mitochondrial proton-transporting ATP synthase complex; mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1); proton-transporting ATP synthase complex
proton transmembrane transporter activity proton-transporting ATP synthase activity, rotational mechanism
Bos taurus
3D-structure Acetylation ATP synthesis CF(1) Direct protein sequencing Hydrogen ion transport Ion transport Membrane Mitochondrion Mitochondrion inner membrane Reference proteome Transit peptide Transport
MLPSALLRRP
MLPSALLRRPGLGRLVRQVRLYAEAAAAQAPAAGPGQMSFTFASPTQVFFNSANVRQVDVPTQTGAFGILAAHVPTLQVLRPGLVVVHAEDGTTSKYFVSSGSVTVNADSSVQLLAEEAVTLDMLDLGAAKANLEKAQSELLGAADEATRAEIQIRIEANEALVKALE
aerobic respiration mitochondrial proton-transporting ATP synthase complex assembly proton motive force-driven ATP synthesis proton motive force-driven mitochondrial ATP synthesis proton transmembrane transport mitochondrial envelope; mitochondrial proton-transporting ATP synthase complex; mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1); proton-transporting ATP synthase complex proton transmembrane transporter activity proton-transporting ATP synthase activity, rotational mechanism Bos taurus 3D-structure Acetylation ATP synthesis CF(1) Direct protein sequencing Hydrogen ion transport Ion transport Membrane Mitochondrion Mitochondrion inner membrane Reference proteome Transit peptide Transport MLPSALLRRP MLPSALLRRPGLGRLVRQVRLYAEAAAAQAPAAGPGQMSFTFASPTQVFFNSANVRQVDVPTQTGAFGILAAHVPTLQVLRPGLVVVHAEDGTTSKYFVSSGSVTVNADSSVQLLAEEAVTLDMLDLGAAKANLEKAQSELLGAADEATRAEIQIRIEANEALVKALE
nucleobase-containing small molecule interconversion response to X-ray RNA decapping
cytoplasm
bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity bis(5'-nucleosyl)-tetraphosphatase activity phosphatase activity
Escherichia coli
Hydrolase Reference proteome
MATYLIGDVH
MATYLIGDVHGCYDELIALLHKVEFTPGKDTLWLTGDLVARGPGSLDVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWLRRQPLLQIDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMPNNWSPELRGLGRLRFITNAFTRMRFCFPNGQLDMYSKESPEEAPAPLKPWFAIPGPVAEEYSIAFGHWASLEGKGTPEGIYALDTGCCWGGTLTCLRWEDKQYFVQPSNRHKDLGEAAAS
nucleobase-containing small molecule interconversion response to X-ray RNA decapping cytoplasm bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity bis(5'-nucleosyl)-tetraphosphatase activity phosphatase activity Escherichia coli Hydrolase Reference proteome MATYLIGDVH MATYLIGDVHGCYDELIALLHKVEFTPGKDTLWLTGDLVARGPGSLDVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWLRRQPLLQIDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMPNNWSPELRGLGRLRFITNAFTRMRFCFPNGQLDMYSKESPEEAPAPLKPWFAIPGPVAEEYSIAFGHWASLEGKGTPEGIYALDTGCCWGGTLTCLRWEDKQYFVQPSNRHKDLGEAAAS
carbohydrate utilization
extracellular region
levansucrase activity
Bacillus subtilis
3D-structure Glycosyltransferase Reference proteome Secreted Signal Transferase
MNIKKFAKQA
MNIKKFAKQATVLTFTTALLAGGATQAFAKETNQKPYKETYGISHITRHDMLQIPEQQKNEKYQVPEFDSSTIKNISSAKGLDVWDSWPLQNADGTVANYHGYHIVFALAGDPKNADDTSIYMFYQKVGETSIDSWKNAGRVFKDSDKFDANDSILKDQTQEWSGSATFTSDGKIRLFYTDFSGKHYGKQTLTTAQVNVSASDSSLNINGVEDYKSIFDGDGKTYQNVQQFIDEGNYSSGDNHTLRDPHYVEDKGHKYLVFEANTGTEDGYQGEESLFNKAYYGKSTSFFRQESQKLLQSDKKRTAELANGALGMIELNDDYTLKKVMKPLIASNTVTDEIERANVFKMNGKWYLFTDSRGSKMTIDGITSNDIYMLGYVSNSLTGPYKPLNKTGLVLKMDLDPNDVTFTYSHFAVPQAKGNNVVITSYMTNRGFYADKQSTFAPSFLLNIKGKKTSVVKDSILEQGQLTVNK
carbohydrate utilization extracellular region levansucrase activity Bacillus subtilis 3D-structure Glycosyltransferase Reference proteome Secreted Signal Transferase MNIKKFAKQA MNIKKFAKQATVLTFTTALLAGGATQAFAKETNQKPYKETYGISHITRHDMLQIPEQQKNEKYQVPEFDSSTIKNISSAKGLDVWDSWPLQNADGTVANYHGYHIVFALAGDPKNADDTSIYMFYQKVGETSIDSWKNAGRVFKDSDKFDANDSILKDQTQEWSGSATFTSDGKIRLFYTDFSGKHYGKQTLTTAQVNVSASDSSLNINGVEDYKSIFDGDGKTYQNVQQFIDEGNYSSGDNHTLRDPHYVEDKGHKYLVFEANTGTEDGYQGEESLFNKAYYGKSTSFFRQESQKLLQSDKKRTAELANGALGMIELNDDYTLKKVMKPLIASNTVTDEIERANVFKMNGKWYLFTDSRGSKMTIDGITSNDIYMLGYVSNSLTGPYKPLNKTGLVLKMDLDPNDVTFTYSHFAVPQAKGNNVVITSYMTNRGFYADKQSTFAPSFLLNIKGKKTSVVKDSILEQGQLTVNK
sucrose catabolic process
cytoplasm; extracellular region
fructan beta-fructosidase activity sucrose alpha-glucosidase activity
Bacillus subtilis
3D-structure Carbohydrate metabolism Glycosidase Hydrolase Reference proteome Secreted Signal
MKKRLIQVMI
MKKRLIQVMIMFTLLLTMAFSADAADSSYYDEDYRPQYHFTPEANWMNDPNGMVYYAGEYHLFYQYHPYGLQWGPMHWGHAVSKDLVTWEHLPVALYPDEKGTIFSGSAVVDKNNTSGFQTGKEKPLVAIYTQDREGHQVQSIAYSNDKGRTWTKYAGNPVIPNPGKKDFRDPKVFWYEKEKKWVMVLAAGDRILIYTSKNLKQWTYASEFGQDQGSHGGVWECPDLFELPVDGNPNQKKWVMQVSVGNGAVSGGSGMQYFVGDFDGTHFKNENPPNKVLWTDYGRDFYAAVSWSDIPSTDSRRLWLGWMSNWQYANDVPTSPWRSATSIPRELKLKAFTEGVRVVQTPVKELETIRGTSKKWKNLTISPASHNVLAGQSGDAYEINAEFKVSPGSAAEFGFKVRTGENQFTKVGYDRRNAKLFVDRSESGNDTFNPAFNTGKETAPLKPVNGKVKLRIFVDRSSVEVFGNDGKQVITDIILPDRSSKGLELYAANGGVKVKSLTIHPLKKVWGTTPFMSNMTGWTTVNGTWADTIEGKQGRSDGDSFILSSASGSDFTYESDITIKDGNGRGAGALMFRSDKDAKNGYLANVDAKHDLVKFFKFENGAASVIAEYKTPIDVNKKYHLKTEAEGDRFKIYLDDRLVIDAHDSVFSEGQFGLNVWDATAVFQNVTKES
sucrose catabolic process cytoplasm; extracellular region fructan beta-fructosidase activity sucrose alpha-glucosidase activity Bacillus subtilis 3D-structure Carbohydrate metabolism Glycosidase Hydrolase Reference proteome Secreted Signal MKKRLIQVMI MKKRLIQVMIMFTLLLTMAFSADAADSSYYDEDYRPQYHFTPEANWMNDPNGMVYYAGEYHLFYQYHPYGLQWGPMHWGHAVSKDLVTWEHLPVALYPDEKGTIFSGSAVVDKNNTSGFQTGKEKPLVAIYTQDREGHQVQSIAYSNDKGRTWTKYAGNPVIPNPGKKDFRDPKVFWYEKEKKWVMVLAAGDRILIYTSKNLKQWTYASEFGQDQGSHGGVWECPDLFELPVDGNPNQKKWVMQVSVGNGAVSGGSGMQYFVGDFDGTHFKNENPPNKVLWTDYGRDFYAAVSWSDIPSTDSRRLWLGWMSNWQYANDVPTSPWRSATSIPRELKLKAFTEGVRVVQTPVKELETIRGTSKKWKNLTISPASHNVLAGQSGDAYEINAEFKVSPGSAAEFGFKVRTGENQFTKVGYDRRNAKLFVDRSESGNDTFNPAFNTGKETAPLKPVNGKVKLRIFVDRSSVEVFGNDGKQVITDIILPDRSSKGLELYAANGGVKVKSLTIHPLKKVWGTTPFMSNMTGWTTVNGTWADTIEGKQGRSDGDSFILSSASGSDFTYESDITIKDGNGRGAGALMFRSDKDAKNGYLANVDAKHDLVKFFKFENGAASVIAEYKTPIDVNKKYHLKTEAEGDRFKIYLDDRLVIDAHDSVFSEGQFGLNVWDATAVFQNVTKES
chemotaxis signal transduction
methyl accepting chemotaxis protein complex; plasma membrane
protein homodimerization activity transmembrane signaling receptor activity
Escherichia coli
Cell inner membrane Cell membrane Chemotaxis Membrane Methylation Reference proteome Transducer Transmembrane Transmembrane helix
MNTTPSQRLG
MNTTPSQRLGFLHHIRLVPLFACILGGILVLFALSSALAGYFLWQADRDQRDVTAEIEIRTGLANSSDFLRSARINMIQAGAASRIAEMEAMKRNIAQAESEIKQSQQGYRAYQNRPVKTPADEALDTELNQRFQAYITGMQPMLKYAKNGMFEAIINHESEQIRPLDNAYTDILNKAVKIRSTRANQLAELAHQRTRLGGMFMIGAFVLALVMTLITFMVLRRIVIRPLQHAAQRIEKIASGDLTMNDEPAGRNEIGRLSRHLQQMQHSLGMTVGTVRQGAEEIYRGTSEISAGNADLSSRTEEQAAAIEQTAASMEQLTATVKQNADNAHHASKLAQEASIKASDGGQTVSGVVKTMGAISTSSKKISEITAVINSIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRTLASRSAQAAKEIEGLISESVRLIDLGSDEVATAGKTMSTIVDAVASVTHIMQEIAAASDEQSRGITQVSQAISEMDKVTQQNASLVEEASAAAVSLEEQAARLTEAVDVFRLHKHSVSAEPRGAGEPVSFATV
chemotaxis signal transduction methyl accepting chemotaxis protein complex; plasma membrane protein homodimerization activity transmembrane signaling receptor activity Escherichia coli Cell inner membrane Cell membrane Chemotaxis Membrane Methylation Reference proteome Transducer Transmembrane Transmembrane helix MNTTPSQRLG MNTTPSQRLGFLHHIRLVPLFACILGGILVLFALSSALAGYFLWQADRDQRDVTAEIEIRTGLANSSDFLRSARINMIQAGAASRIAEMEAMKRNIAQAESEIKQSQQGYRAYQNRPVKTPADEALDTELNQRFQAYITGMQPMLKYAKNGMFEAIINHESEQIRPLDNAYTDILNKAVKIRSTRANQLAELAHQRTRLGGMFMIGAFVLALVMTLITFMVLRRIVIRPLQHAAQRIEKIASGDLTMNDEPAGRNEIGRLSRHLQQMQHSLGMTVGTVRQGAEEIYRGTSEISAGNADLSSRTEEQAAAIEQTAASMEQLTATVKQNADNAHHASKLAQEASIKASDGGQTVSGVVKTMGAISTSSKKISEITAVINSIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRTLASRSAQAAKEIEGLISESVRLIDLGSDEVATAGKTMSTIVDAVASVTHIMQEIAAASDEQSRGITQVSQAISEMDKVTQQNASLVEEASAAAVSLEEQAARLTEAVDVFRLHKHSVSAEPRGAGEPVSFATV
canonical glycolysis carbohydrate phosphorylation establishment of protein localization to mitochondrion fructose 6-phosphate metabolic process glucose 6-phosphate metabolic process glucose metabolic process glycolytic process inflammatory response innate immune response intracellular glucose homeostasis maintenance of protein location in mitochondrion mannose metabolic process negative regulation of apoptotic process positive regulation of cytokine production involved in immune response positive regulation of interleukin-1 beta production response to brassinosteroid response to hypoxia response to ischemia response to ketamine
caveola; cytosol; membrane raft; mitochondrial outer membrane; mitochondrion; protein-containing complex
ATP binding ATP hydrolysis activity fructokinase activity glucokinase activity glucosamine kinase activity glucose binding hexokinase activity identical protein binding mannokinase activity peptidoglycan binding protein kinase activity protein-containing complex binding
Rattus norvegicus
3D-structure Acetylation Allosteric enzyme ATP-binding Cytoplasm Direct protein sequencing Glycolysis Immunity Inflammatory response Innate immunity Kinase Membrane Mitochondrion Mitochondrion outer membrane Nucleotide-binding Phosphoprotein Reference proteome Repeat Transferase
MIAAQLLAYY
MIAAQLLAYYFTELKDDQVKKIDKYLYAMRLSDEILIDILTRFKKEMKNGLSRDYNPTASVKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEKNQNVSMESEIYDTPENIVHGSGTQLFDHVADCLGDFMEKKKIKDKKLPVGFTFSFPCRQSKIDEAVLITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQQCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDRELDRGSLNPGKQLFEKMVSGMYMGELVRLILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEKDKEGIQNAKEILTRLGVEPSDVDCVSVQHICTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKMHPQYSRRFHKTLRRLVPDSDVRFLLSESGTGKGAAMVTAVAYRLAEQHRQIEETLAHFRLSKQTLMEVKKRLRTEMEMGLRKETNSKATVKMLPSFVRSIPDGTEHGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYSIPLEIMQGTGDELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCHQTNLDCGILISWTKGFKATDCEGHDVASLLRDAVKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEIGLIVGTGTNACYMEEMKNVEMVEGNQGQMCINMEWGAFGDNGCLDDIRTDFDKVVDEYSLNSGKQRFEKMISGMYLGEIVRNILIDFTKKGFLFRGQISEPLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSKRAAQLCGAGMAAVVEKIRENRGLDHLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCTVSFLLSEDGSGKGAALITAVGVRLRGDPSIA
canonical glycolysis carbohydrate phosphorylation establishment of protein localization to mitochondrion fructose 6-phosphate metabolic process glucose 6-phosphate metabolic process glucose metabolic process glycolytic process inflammatory response innate immune response intracellular glucose homeostasis maintenance of protein location in mitochondrion mannose metabolic process negative regulation of apoptotic process positive regulation of cytokine production involved in immune response positive regulation of interleukin-1 beta production response to brassinosteroid response to hypoxia response to ischemia response to ketamine caveola; cytosol; membrane raft; mitochondrial outer membrane; mitochondrion; protein-containing complex ATP binding ATP hydrolysis activity fructokinase activity glucokinase activity glucosamine kinase activity glucose binding hexokinase activity identical protein binding mannokinase activity peptidoglycan binding protein kinase activity protein-containing complex binding Rattus norvegicus 3D-structure Acetylation Allosteric enzyme ATP-binding Cytoplasm Direct protein sequencing Glycolysis Immunity Inflammatory response Innate immunity Kinase Membrane Mitochondrion Mitochondrion outer membrane Nucleotide-binding Phosphoprotein Reference proteome Repeat Transferase MIAAQLLAYY MIAAQLLAYYFTELKDDQVKKIDKYLYAMRLSDEILIDILTRFKKEMKNGLSRDYNPTASVKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEKNQNVSMESEIYDTPENIVHGSGTQLFDHVADCLGDFMEKKKIKDKKLPVGFTFSFPCRQSKIDEAVLITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQQCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDRELDRGSLNPGKQLFEKMVSGMYMGELVRLILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEKDKEGIQNAKEILTRLGVEPSDVDCVSVQHICTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKMHPQYSRRFHKTLRRLVPDSDVRFLLSESGTGKGAAMVTAVAYRLAEQHRQIEETLAHFRLSKQTLMEVKKRLRTEMEMGLRKETNSKATVKMLPSFVRSIPDGTEHGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYSIPLEIMQGTGDELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCHQTNLDCGILISWTKGFKATDCEGHDVASLLRDAVKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEIGLIVGTGTNACYMEEMKNVEMVEGNQGQMCINMEWGAFGDNGCLDDIRTDFDKVVDEYSLNSGKQRFEKMISGMYLGEIVRNILIDFTKKGFLFRGQISEPLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSKRAAQLCGAGMAAVVEKIRENRGLDHLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCTVSFLLSEDGSGKGAALITAVGVRLRGDPSIA
adult walking behavior axonogenesis brain development determination of genital disc primordium ectoderm development locomotion positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of transcription by RNA polymerase II ventral cord development ventral midline development
cytoplasm; nucleus; transcription regulator complex
DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific protein heterodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific DNA binding
Drosophila melanogaster
Alternative splicing Developmental protein Differentiation DNA-binding Neurogenesis Nucleus Reference proteome Repeat Transcription Transcription regulation
MTNHRRVRKD
MTNHRRVRKDCYESRLHDIAKTCAMKEKSKNAARTRREKENTEFCELAKLLPLPAAITSQLDKASVIRLTTSYLKMRQVFPDGLGEAWGSSPAMQRGATIKELGSHLLQTLDGFIFVVAPDGKIMYISETASVHLGLSQVELTGNSIFEYIHNYDQDEMNAILSLHPHINQHPLAQTHTPIGSPNGVQHPSAYDHDRGSHTIEIEKTFFLRMKCVLAKRNAGLTTSGFKVIHCSGYLKARIYPDRGDGQGSLIQNLGLVAVGHSLPSSAITEIKLHQNMFMFRAKLDMKLIFFDARVSQLTGYEPQDLIEKTLYQYIHAADIMAMRCSHQILLYKGQVTTKYYRFLTKGGGWVWVQSYATLVHNSRSSREVFIVSVNYVLSEREVKDLVLNEIQTGVVKREPISPAAQAAQAAQAAQAAQAAQAAQAAQAAQAAQAAHVAQAVQAQVVVVPQQSVVVQPQCAGATGQPVGPGTPVSLALSASPKLDPYFEPELPLQPAVTPVPPTNNSSSSSNNNNGVWHHHHVQQQQQSGSMDHDSLSYTQLYPPLNDLVVSSSSSVGGGTASSAGGGSSASASSSGVYSTEMQYPDTTTGNLYYNNNNHYYYDYDATVDVATSMIRPFSANSNSCSSSSESERQLSTGNASIVNETSPSQTTYSDLSHNFELSYFSDNSSQQHQHQQQQQHLMEQQHLQYQYATW
adult walking behavior axonogenesis brain development determination of genital disc primordium ectoderm development locomotion positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of transcription by RNA polymerase II ventral cord development ventral midline development cytoplasm; nucleus; transcription regulator complex DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific protein heterodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific DNA binding Drosophila melanogaster Alternative splicing Developmental protein Differentiation DNA-binding Neurogenesis Nucleus Reference proteome Repeat Transcription Transcription regulation MTNHRRVRKD MTNHRRVRKDCYESRLHDIAKTCAMKEKSKNAARTRREKENTEFCELAKLLPLPAAITSQLDKASVIRLTTSYLKMRQVFPDGLGEAWGSSPAMQRGATIKELGSHLLQTLDGFIFVVAPDGKIMYISETASVHLGLSQVELTGNSIFEYIHNYDQDEMNAILSLHPHINQHPLAQTHTPIGSPNGVQHPSAYDHDRGSHTIEIEKTFFLRMKCVLAKRNAGLTTSGFKVIHCSGYLKARIYPDRGDGQGSLIQNLGLVAVGHSLPSSAITEIKLHQNMFMFRAKLDMKLIFFDARVSQLTGYEPQDLIEKTLYQYIHAADIMAMRCSHQILLYKGQVTTKYYRFLTKGGGWVWVQSYATLVHNSRSSREVFIVSVNYVLSEREVKDLVLNEIQTGVVKREPISPAAQAAQAAQAAQAAQAAQAAQAAQAAQAAQAAHVAQAVQAQVVVVPQQSVVVQPQCAGATGQPVGPGTPVSLALSASPKLDPYFEPELPLQPAVTPVPPTNNSSSSSNNNNGVWHHHHVQQQQQSGSMDHDSLSYTQLYPPLNDLVVSSSSSVGGGTASSAGGGSSASASSSGVYSTEMQYPDTTTGNLYYNNNNHYYYDYDATVDVATSMIRPFSANSNSCSSSSESERQLSTGNASIVNETSPSQTTYSDLSHNFELSYFSDNSSQQHQHQQQQQHLMEQQHLQYQYATW
cellular response to granulocyte macrophage colony-stimulating factor stimulus cytokine-mediated signaling pathway lactation mammary gland alveolus development mammary gland epithelial cell differentiation mammary gland epithelium development negative regulation of apoptotic process positive regulation of B cell proliferation positive regulation of cell population proliferation positive regulation of cold-induced thermogenesis positive regulation of protein autophosphorylation prostate gland growth receptor signaling pathway via JAK-STAT regulation of cell adhesion regulation of epithelial cell differentiation response to bacterium
cell surface; external side of plasma membrane; plasma membrane; receptor complex
cytokine binding lipid binding metal ion binding peptide hormone binding prolactin receptor activity protein kinase binding
Rattus norvegicus
3D-structure Alternative splicing Direct protein sequencing Disulfide bond Glycoprotein Membrane Metal-binding Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix Zinc
MPSALAFVLL
MPSALAFVLLVLNISLLKGQSPPGKPEIHKCRSPDKETFTCWWNPGTDGGLPTNYSLTYSKEGEKTTYECPDYKTSGPNSCFFSKQYTSIWKIYIITVNATNQMGSSSSDPLYVDVTYIVEPEPPRNLTLEVKQLKDKKTYLWVKWSPPTITDVKTGWFTMEYEIRLKPEEAEEWEIHFTGHQTQFKVFDLYPGQKYLVQTRCKPDHGYWSRWSQESSVEMPNDFTLKDTTVWIIVAILSAVICLIMVWAVALKGYSMMTCIFPPVPGPKIKGFDTHLLEKGKSEELLSALGCQDFPPTSDCEDLLVEFLEVDDNEDERLMPSHSKEYPGQGVKPTHLDPDSDSGHGSYDSHSLLSEKCEEPQAYPPTLHIPEITEKPENPEANIPPTVDPQSTNPNFHVDAPKSSTWPLLPGQHMPRSPYHSVADVCKLAGSPVNTLDSFLDKAEENVLKLSKALETGEEEVAEQKGAKSFPSDKQNTPWPLLQEKSPTVYVKPPDYVEIHKVNKDGVLSLFPKQRENNQTEKPGVPETSKEYAKVSGITDNNILVLVPDSRAQNTALLEESAKKAPPSFEADQSEKDLASFTATSSNRRLQLGRLDYLDPTCFMHSFH
cellular response to granulocyte macrophage colony-stimulating factor stimulus cytokine-mediated signaling pathway lactation mammary gland alveolus development mammary gland epithelial cell differentiation mammary gland epithelium development negative regulation of apoptotic process positive regulation of B cell proliferation positive regulation of cell population proliferation positive regulation of cold-induced thermogenesis positive regulation of protein autophosphorylation prostate gland growth receptor signaling pathway via JAK-STAT regulation of cell adhesion regulation of epithelial cell differentiation response to bacterium cell surface; external side of plasma membrane; plasma membrane; receptor complex cytokine binding lipid binding metal ion binding peptide hormone binding prolactin receptor activity protein kinase binding Rattus norvegicus 3D-structure Alternative splicing Direct protein sequencing Disulfide bond Glycoprotein Membrane Metal-binding Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix Zinc MPSALAFVLL MPSALAFVLLVLNISLLKGQSPPGKPEIHKCRSPDKETFTCWWNPGTDGGLPTNYSLTYSKEGEKTTYECPDYKTSGPNSCFFSKQYTSIWKIYIITVNATNQMGSSSSDPLYVDVTYIVEPEPPRNLTLEVKQLKDKKTYLWVKWSPPTITDVKTGWFTMEYEIRLKPEEAEEWEIHFTGHQTQFKVFDLYPGQKYLVQTRCKPDHGYWSRWSQESSVEMPNDFTLKDTTVWIIVAILSAVICLIMVWAVALKGYSMMTCIFPPVPGPKIKGFDTHLLEKGKSEELLSALGCQDFPPTSDCEDLLVEFLEVDDNEDERLMPSHSKEYPGQGVKPTHLDPDSDSGHGSYDSHSLLSEKCEEPQAYPPTLHIPEITEKPENPEANIPPTVDPQSTNPNFHVDAPKSSTWPLLPGQHMPRSPYHSVADVCKLAGSPVNTLDSFLDKAEENVLKLSKALETGEEEVAEQKGAKSFPSDKQNTPWPLLQEKSPTVYVKPPDYVEIHKVNKDGVLSLFPKQRENNQTEKPGVPETSKEYAKVSGITDNNILVLVPDSRAQNTALLEESAKKAPPSFEADQSEKDLASFTATSSNRRLQLGRLDYLDPTCFMHSFH
Golgi organization protein transport Rab protein signal transduction vesicle-mediated transport
acrosomal vesicle; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment membrane; Golgi apparatus; Golgi membrane; melanosome; membrane; neuronal cell body; perinuclear region of cytoplasm; synaptic vesicle membrane
GDP binding GTP binding GTPase activity
Rattus norvegicus
Acetylation Cytoplasmic vesicle Endoplasmic reticulum ER-Golgi transport Golgi apparatus GTP-binding Hydrolase Lipoprotein Membrane Nucleotide-binding Prenylation Protein transport Reference proteome Transport
MAYAYLFKYI
MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTMGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNASHGGNQGGQQAGGGCC
Golgi organization protein transport Rab protein signal transduction vesicle-mediated transport acrosomal vesicle; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment membrane; Golgi apparatus; Golgi membrane; melanosome; membrane; neuronal cell body; perinuclear region of cytoplasm; synaptic vesicle membrane GDP binding GTP binding GTPase activity Rattus norvegicus Acetylation Cytoplasmic vesicle Endoplasmic reticulum ER-Golgi transport Golgi apparatus GTP-binding Hydrolase Lipoprotein Membrane Nucleotide-binding Prenylation Protein transport Reference proteome Transport MAYAYLFKYI MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTMGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNASHGGNQGGQQAGGGCC
antigen processing and presentation protein transport Rab protein signal transduction regulation of endocytosis small GTPase mediated signal transduction vesicle-mediated transport
cytoplasm; early endosome membrane; endosome; extracellular exosome; insulin-responsive compartment; perinuclear region of cytoplasm; postsynaptic recycling endosome; recycling endosome; recycling endosome membrane; synaptic vesicle membrane; vesicle
ATPase activator activity ATPase binding G protein activity GDP binding GTP binding GTPase activity ionotropic glutamate receptor binding syntaxin binding
Rattus norvegicus
Cytoplasm Endosome GTP-binding Hydrolase Lipoprotein Membrane Methylation Nucleotide-binding Phosphoprotein Prenylation Protein transport Reference proteome Transport
MAQTAMSETY
MAQTAMSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGKYVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCGNKKDLDADREVTFLEASRFAQENELMFLETSALTGENVEEAFMQCARKILNKIESGELDPERMGSGIQYGDAALRQLRSPRRTQAPSAQECGC
antigen processing and presentation protein transport Rab protein signal transduction regulation of endocytosis small GTPase mediated signal transduction vesicle-mediated transport cytoplasm; early endosome membrane; endosome; extracellular exosome; insulin-responsive compartment; perinuclear region of cytoplasm; postsynaptic recycling endosome; recycling endosome; recycling endosome membrane; synaptic vesicle membrane; vesicle ATPase activator activity ATPase binding G protein activity GDP binding GTP binding GTPase activity ionotropic glutamate receptor binding syntaxin binding Rattus norvegicus Cytoplasm Endosome GTP-binding Hydrolase Lipoprotein Membrane Methylation Nucleotide-binding Phosphoprotein Prenylation Protein transport Reference proteome Transport MAQTAMSETY MAQTAMSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGKYVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCGNKKDLDADREVTFLEASRFAQENELMFLETSALTGENVEEAFMQCARKILNKIESGELDPERMGSGIQYGDAALRQLRSPRRTQAPSAQECGC
intron homing
chloroplast
endonuclease activity identical protein binding metal ion binding
Chlamydomonas reinhardtii
3D-structure Chloroplast Endonuclease Hydrolase Intron homing Magnesium Metal-binding Nuclease Plastid
MNTKYNKEFL
MNTKYNKEFLLYLAGFVDGDGSIIAQIKPNQSYKFKHQLSLTFQVTQKTQRRWFLDKLVDEIGVGYVRDRGSVSDYILSEIKPLHNFLTQLQPFLKLKQKQANLVLKIIEQLPSAKESPDKFLEVCTWVDQIAALNDSKTRKTTSETVRAVLDSLSEKKKSSP
intron homing chloroplast endonuclease activity identical protein binding metal ion binding Chlamydomonas reinhardtii 3D-structure Chloroplast Endonuclease Hydrolase Intron homing Magnesium Metal-binding Nuclease Plastid MNTKYNKEFL MNTKYNKEFLLYLAGFVDGDGSIIAQIKPNQSYKFKHQLSLTFQVTQKTQRRWFLDKLVDEIGVGYVRDRGSVSDYILSEIKPLHNFLTQLQPFLKLKQKQANLVLKIIEQLPSAKESPDKFLEVCTWVDQIAALNDSKTRKTTSETVRAVLDSLSEKKKSSP
cytoplasmic translation maturation of LSU-rRNA maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosomal large subunit biogenesis
cytoplasm; cytosol; cytosolic large ribosomal subunit
RNA binding structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Cytoplasm Direct protein sequencing Reference proteome Ribonucleoprotein Ribosomal protein
MAAEKILTPE
MAAEKILTPESQLKKSKAQQKTAEQVAAERAARKAANKEKRAIILERNAAYQKEYETAERNIIQAKRDAKAAGSYYVEAQHKLVFVVRIKGINKIPPKPRKVLQLLRLTRINSGTFVKVTKATLELLKLIEPYVAYGYPSYSTIRQLVYKRGFGKINKQRVPLSDNAIIEANLGKYGILSIDDLIHEIITVGPHFKQANNFLWPFKLSNPSGGWGVPRKFKHFIQGGSFGNREEFINKLVKSMN
cytoplasmic translation maturation of LSU-rRNA maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosomal large subunit biogenesis cytoplasm; cytosol; cytosolic large ribosomal subunit RNA binding structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Cytoplasm Direct protein sequencing Reference proteome Ribonucleoprotein Ribosomal protein MAAEKILTPE MAAEKILTPESQLKKSKAQQKTAEQVAAERAARKAANKEKRAIILERNAAYQKEYETAERNIIQAKRDAKAAGSYYVEAQHKLVFVVRIKGINKIPPKPRKVLQLLRLTRINSGTFVKVTKATLELLKLIEPYVAYGYPSYSTIRQLVYKRGFGKINKQRVPLSDNAIIEANLGKYGILSIDDLIHEIITVGPHFKQANNFLWPFKLSNPSGGWGVPRKFKHFIQGGSFGNREEFINKLVKSMN
cytoplasmic translation ribosomal large subunit assembly
cytosol; cytosolic large ribosomal subunit
RNA binding structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation
MTAQQAPKWY
MTAQQAPKWYPSEDVAAPKKTRKAVRPQKLRASLVPGTVLILLAGRFRGKRVVYLKHLEDNTLLVTGPFKVNGVPLRRVNARYVIATSTKVSVEGVNVEKFNVEYFAKEKLTKKEKKEANLFPEQQTKEIKTERVEDQKVVDKALLAEIKKTPLLKQYLSASFSLKNGDKPHLLKF
cytoplasmic translation ribosomal large subunit assembly cytosol; cytosolic large ribosomal subunit RNA binding structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation MTAQQAPKWY MTAQQAPKWYPSEDVAAPKKTRKAVRPQKLRASLVPGTVLILLAGRFRGKRVVYLKHLEDNTLLVTGPFKVNGVPLRRVNARYVIATSTKVSVEGVNVEKFNVEYFAKEKLTKKEKKEANLFPEQQTKEIKTERVEDQKVVDKALLAEIKKTPLLKQYLSASFSLKNGDKPHLLKF
cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) cytoplasmic translation
cytoplasm; cytosol; cytosolic large ribosomal subunit; preribosome, large subunit precursor
structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation
MARYGATSTN
MARYGATSTNPAKSASARGSYLRVSFKNTRETAQAINGWELTKAQKYLEQVLDHQRAIPFRRFNSSIGRTAQGKEFGVTKARWPAKSVKFVQGLLQNAAANAEAKGLDATKLYVSHIQVNQAPKQRRRTYRAHGRINKYESSPSHIELVVTEKEEAVAKAAEKKVVRLTSRQRGRIAAQKRIAA
cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) cytoplasmic translation cytoplasm; cytosol; cytosolic large ribosomal subunit; preribosome, large subunit precursor structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation MARYGATSTN MARYGATSTNPAKSASARGSYLRVSFKNTRETAQAINGWELTKAQKYLEQVLDHQRAIPFRRFNSSIGRTAQGKEFGVTKARWPAKSVKFVQGLLQNAAANAEAKGLDATKLYVSHIQVNQAPKQRRRTYRAHGRINKYESSPSHIELVVTEKEEAVAKAAEKKVVRLTSRQRGRIAAQKRIAA
cytoplasmic translation ribosomal large subunit biogenesis
cytosol; cytosolic large ribosomal subunit
structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Acetylation Cytoplasm Direct protein sequencing Isopeptide bond Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation
MAESHRLYVK
MAESHRLYVKGKHLSYQRSKRVNNPNVSLIKIEGVATPQDAQFYLGKRIAYVYRASKEVRGSKIRVMWGKVTRTHGNSGVVRATFRNNLPAKTFGASVRIFLYPSNI
cytoplasmic translation ribosomal large subunit biogenesis cytosol; cytosolic large ribosomal subunit structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Acetylation Cytoplasm Direct protein sequencing Isopeptide bond Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation MAESHRLYVK MAESHRLYVKGKHLSYQRSKRVNNPNVSLIKIEGVATPQDAQFYLGKRIAYVYRASKEVRGSKIRVMWGKVTRTHGNSGVVRATFRNNLPAKTFGASVRIFLYPSNI
cytoplasmic translation
cytosol; cytosolic large ribosomal subunit
RNA binding structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Acetylation Cytoplasm Reference proteome Ribonucleoprotein Ribosomal protein
MTVKTGIAIG
MTVKTGIAIGLNKGKKVTSMTPAPKISYKKGAASNRTKFVRSLVREIAGLSPYERRLIDLIRNSGEKRARKVAKKRLGSFTRAKAKVEEMNNIIAASRRH
cytoplasmic translation cytosol; cytosolic large ribosomal subunit RNA binding structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Acetylation Cytoplasm Reference proteome Ribonucleoprotein Ribosomal protein MTVKTGIAIG MTVKTGIAIGLNKGKKVTSMTPAPKISYKKGAASNRTKFVRSLVREIAGLSPYERRLIDLIRNSGEKRARKVAKKRLGSFTRAKAKVEEMNNIIAASRRH
cytoplasmic translation
cytosol; cytosolic large ribosomal subunit
RNA binding structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Cytoplasm Direct protein sequencing Reference proteome Ribonucleoprotein Ribosomal protein
MGAYKYLEEL
MGAYKYLEELQRKKQSDVLRFLQRVRVWEYRQKNVIHRAARPTRPDKARRLGYKAKQGFVIYRVRVRRGNRKRPVPKGATYGKPTNQGVNELKYQRSLRATAEERVGRRAANLRVLNSYWVNQDSTYKYFEVILVDPQHKAIRRDARYNWICDPVHKHREARGLTATGKKSRGINKGHKFNNTKAGRRKTWKRQNTLSLWRYRK
cytoplasmic translation cytosol; cytosolic large ribosomal subunit RNA binding structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Cytoplasm Direct protein sequencing Reference proteome Ribonucleoprotein Ribosomal protein MGAYKYLEEL MGAYKYLEELQRKKQSDVLRFLQRVRVWEYRQKNVIHRAARPTRPDKARRLGYKAKQGFVIYRVRVRRGNRKRPVPKGATYGKPTNQGVNELKYQRSLRATAEERVGRRAANLRVLNSYWVNQDSTYKYFEVILVDPQHKAIRRDARYNWICDPVHKHREARGLTATGKKSRGINKGHKFNNTKAGRRKTWKRQNTLSLWRYRK
cytoplasmic translation ribosomal small subunit export from nucleus rRNA export from nucleus
90S preribosome; cytoplasm; cytosol; cytosolic small ribosomal subunit; nucleus; preribosome, small subunit precursor
DNA-(apurinic or apyrimidinic site) endonuclease activity RNA binding structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Methylation Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding Ubl conjugation
MVALISKKRK
MVALISKKRKLVADGVFYAELNEFFTRELAEEGYSGVEVRVTPTKTEVIIRATRTQDVLGENGRRINELTLLVQKRFKYAPGTIVLYAERVQDRGLSAVAQAESMKFKLLNGLAIRRAAYGVVRYVMESGAKGCEVVVSGKLRAARAKAMKFADGFLIHSGQPVNDFIDTATRHVLMRQGVLGIKVKIMRDPAKSRTGPKALPDAVTIIEPKEEEPILAPSVKDYRPAEETEAQAEPVEA
cytoplasmic translation ribosomal small subunit export from nucleus rRNA export from nucleus 90S preribosome; cytoplasm; cytosol; cytosolic small ribosomal subunit; nucleus; preribosome, small subunit precursor DNA-(apurinic or apyrimidinic site) endonuclease activity RNA binding structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Methylation Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding Ubl conjugation MVALISKKRK MVALISKKRKLVADGVFYAELNEFFTRELAEEGYSGVEVRVTPTKTEVIIRATRTQDVLGENGRRINELTLLVQKRFKYAPGTIVLYAERVQDRGLSAVAQAESMKFKLLNGLAIRRAAYGVVRYVMESGAKGCEVVVSGKLRAARAKAMKFADGFLIHSGQPVNDFIDTATRHVLMRQGVLGIKVKIMRDPAKSRTGPKALPDAVTIIEPKEEEPILAPSVKDYRPAEETEAQAEPVEA
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) positive regulation of translational fidelity ribosomal small subunit biogenesis translation
90S preribosome; cytosol; cytosolic small ribosomal subunit; nucleolus; small-subunit processome
rRNA binding structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Nucleus Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Ribosome biogenesis RNA-binding rRNA processing rRNA-binding Ubl conjugation
MPRAPRTYSK
MPRAPRTYSKTYSTPKRPYESSRLDAELKLAGEFGLKNKREIYRISFQLSKIRRAARDLLTRDEKDPKRLFEGNALIRRLVRVGVLSEDKKKLDYVLALKVEDFLERRLQTQVYKLGLAKSVHHARVLITQRHIAVGKQIVNIPSFMVRLDSEKHIDFAPTSPFGGARPGRVARRNAARKAEASGEAAEEAEDEE
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) positive regulation of translational fidelity ribosomal small subunit biogenesis translation 90S preribosome; cytosol; cytosolic small ribosomal subunit; nucleolus; small-subunit processome rRNA binding structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Nucleus Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Ribosome biogenesis RNA-binding rRNA processing rRNA-binding Ubl conjugation MPRAPRTYSK MPRAPRTYSKTYSTPKRPYESSRLDAELKLAGEFGLKNKREIYRISFQLSKIRRAARDLLTRDEKDPKRLFEGNALIRRLVRVGVLSEDKKKLDYVLALKVEDFLERRLQTQVYKLGLAKSVHHARVLITQRHIAVGKQIVNIPSFMVRLDSEKHIDFAPTSPFGGARPGRVARRNAARKAEASGEAAEEAEDEE
cytoplasmic translation maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
90S preribosome; cytoplasm; cytosol; cytosolic small ribosomal subunit; nucleolus
small ribosomal subunit rRNA binding structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation
MGRMHSAGKG
MGRMHSAGKGISSSAIPYSRNAPAWFKLSSESVIEQIVKYARKGLTPSQIGVLLRDAHGVTQARVITGNKIMRILKSNGLAPEIPEDLYYLIKKAVSVRKHLERNRKDKDAKFRLILIESRIHRLARYYRTVAVLPPNWKYESATASALVN
cytoplasmic translation maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 90S preribosome; cytoplasm; cytosol; cytosolic small ribosomal subunit; nucleolus small ribosomal subunit rRNA binding structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation MGRMHSAGKG MGRMHSAGKGISSSAIPYSRNAPAWFKLSSESVIEQIVKYARKGLTPSQIGVLLRDAHGVTQARVITGNKIMRILKSNGLAPEIPEDLYYLIKKAVSVRKHLERNRKDKDAKFRLILIESRIHRLARYYRTVAVLPPNWKYESATASALVN
cytoplasmic translation maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S) modification-dependent protein catabolic process protein ubiquitination ribosomal small subunit assembly ribosome biogenesis
cytoplasm; cytosol; cytosolic small ribosomal subunit; nucleus
metal ion binding protein tag activity structural constituent of ribosome ubiquitin protein ligase binding
Saccharomyces cerevisiae
3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Metal-binding Nucleus Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation Zinc Zinc-finger
MQIFVKTLTG
MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGGKKRKKKVYTTPKKIKHKHKKVKLAVLSYYKVDAEGKVTKLRRECSNPTCGAGVFLANHKDRLYCGKCHSVYKVNA
cytoplasmic translation maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S) modification-dependent protein catabolic process protein ubiquitination ribosomal small subunit assembly ribosome biogenesis cytoplasm; cytosol; cytosolic small ribosomal subunit; nucleus metal ion binding protein tag activity structural constituent of ribosome ubiquitin protein ligase binding Saccharomyces cerevisiae 3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Metal-binding Nucleus Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation Zinc Zinc-finger MQIFVKTLTG MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGGKKRKKKVYTTPKKIKHKHKKVKLAVLSYYKVDAEGKVTKLRRECSNPTCGAGVFLANHKDRLYCGKCHSVYKVNA
cytoplasmic translational elongation endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosomal small subunit biogenesis
cytosol; cytosolic small ribosomal subunit; nucleus
structural constituent of ribosome
Schizosaccharomyces pombe
Acetylation Cytoplasm Direct protein sequencing Nucleus Reference proteome Ribonucleoprotein Ribosomal protein rRNA processing
MENEAGQLVD
MENEAGQLVDLYVPRKCSATNRIIQAKDHASVQINVCAVDAEGRQIPGEKTTYAISGFVRSKGESDDCINRLTTQDGLLEGVWSYQR
cytoplasmic translational elongation endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosomal small subunit biogenesis cytosol; cytosolic small ribosomal subunit; nucleus structural constituent of ribosome Schizosaccharomyces pombe Acetylation Cytoplasm Direct protein sequencing Nucleus Reference proteome Ribonucleoprotein Ribosomal protein rRNA processing MENEAGQLVD MENEAGQLVDLYVPRKCSATNRIIQAKDHASVQINVCAVDAEGRQIPGEKTTYAISGFVRSKGESDDCINRLTTQDGLLEGVWSYQR
adaptive immune response apoptotic process B cell activation B cell receptor signaling pathway negative regulation of glucose transmembrane transport negative regulation of insulin receptor signaling pathway phosphorylation positive regulation of angiogenesis positive regulation of B cell receptor signaling pathway positive regulation of canonical NF-kappaB signal transduction positive regulation of vascular endothelial growth factor receptor signaling pathway post-translational protein modification regulation of glucose transmembrane transport regulation of transcription by RNA polymerase II
cytoplasm; membrane; nucleus
ATP binding chromatin binding diacylglycerol-dependent serine/threonine kinase activity histone binding histone H3T6 kinase activity nuclear androgen receptor binding nuclear receptor coactivator activity protein serine kinase activity zinc ion binding
Oryctolagus cuniculus
Acetylation Adaptive immunity Alternative splicing Apoptosis ATP-binding Calcium Chromatin regulator Cytoplasm Immunity Kinase Membrane Metal-binding Nucleotide-binding Nucleus Phosphoprotein Reference proteome Repeat Serine/threonine-protein kinase Transcription Transcription regulation Transferase Zinc Zinc-finger
MADPAAGQPP
MADPAAGQPPSEGEESTVRFARKGALRQKNVHEVKNHKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIDREVLIVVVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKAGVDGWFKLLSQEEGEYFNVPVPPEGSEGNEELRQKFERAKIGQGTKTPEEKTTNTISKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKDHAFFRYIDWEKLERKEIQPPYKPKARDKRDTSNFDKEFTRQPVELTPTDKLFIMNLDQNEFAGFSYTNPEFVINV
adaptive immune response apoptotic process B cell activation B cell receptor signaling pathway negative regulation of glucose transmembrane transport negative regulation of insulin receptor signaling pathway phosphorylation positive regulation of angiogenesis positive regulation of B cell receptor signaling pathway positive regulation of canonical NF-kappaB signal transduction positive regulation of vascular endothelial growth factor receptor signaling pathway post-translational protein modification regulation of glucose transmembrane transport regulation of transcription by RNA polymerase II cytoplasm; membrane; nucleus ATP binding chromatin binding diacylglycerol-dependent serine/threonine kinase activity histone binding histone H3T6 kinase activity nuclear androgen receptor binding nuclear receptor coactivator activity protein serine kinase activity zinc ion binding Oryctolagus cuniculus Acetylation Adaptive immunity Alternative splicing Apoptosis ATP-binding Calcium Chromatin regulator Cytoplasm Immunity Kinase Membrane Metal-binding Nucleotide-binding Nucleus Phosphoprotein Reference proteome Repeat Serine/threonine-protein kinase Transcription Transcription regulation Transferase Zinc Zinc-finger MADPAAGQPP MADPAAGQPPSEGEESTVRFARKGALRQKNVHEVKNHKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIDREVLIVVVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKAGVDGWFKLLSQEEGEYFNVPVPPEGSEGNEELRQKFERAKIGQGTKTPEEKTTNTISKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKDHAFFRYIDWEKLERKEIQPPYKPKARDKRDTSNFDKEFTRQPVELTPTDKLFIMNLDQNEFAGFSYTNPEFVINV
viral budding from plasma membrane
host cell nucleus; membrane; virion membrane
RNA binding structural constituent of virion
Influenza A virus )
3D-structure Alternative splicing Host nucleus Membrane Reference proteome RNA-binding Viral matrix protein Virion
MSLLTEVETY
MSLLTEVETYVLSIVPSGPLKAEIAQRLEDVFAGKNTDLEVLMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDKAVKLYRKLKREITFHGAKEIALSYSAGALASCMGLIYNRMGAVTTEVAFGLVCATCEQIADSQHRSHRQMVTTTNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMDIASQARQMVQAMRTIGTHPSSSAGLKDDLLENLQAYQKRMGVQMQRFK
viral budding from plasma membrane host cell nucleus; membrane; virion membrane RNA binding structural constituent of virion Influenza A virus )3D-structure Alternative splicing Host nucleus Membrane Reference proteome RNA-binding Viral matrix protein Virion MSLLTEVETY MSLLTEVETYVLSIVPSGPLKAEIAQRLEDVFAGKNTDLEVLMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDKAVKLYRKLKREITFHGAKEIALSYSAGALASCMGLIYNRMGAVTTEVAFGLVCATCEQIADSQHRSHRQMVTTTNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMDIASQARQMVQAMRTIGTHPSSSAGLKDDLLENLQAYQKRMGVQMQRFK
protein complex oligomerization suppression by virus of host autophagy virus-mediated pore formation in host cell membrane
host cell plasma membrane; membrane; virion membrane
monoatomic ion channel activity proton transmembrane transporter activity
Influenza A virus
Alternative splicing Disulfide bond Glycoprotein Host cell membrane Host membrane Host-virus interaction Hydrogen ion transport Inhibition of host autophagy by virus Ion channel Ion transport Lipoprotein Membrane Palmitate Phosphoprotein Signal-anchor Transmembrane Transmembrane helix Transport Viral ion channel Virion
MSLPTEVETP
MSLPTEVETPTRNEWGCRCNDSSDHITIAAKFIGILHLILWILDRLFFKCIYRRLKYGPKRGPSTEGVPDSMREEYRQKQQNAADVDDGHFVNIELE
protein complex oligomerization suppression by virus of host autophagy virus-mediated pore formation in host cell membrane host cell plasma membrane; membrane; virion membrane monoatomic ion channel activity proton transmembrane transporter activity Influenza A virus Alternative splicing Disulfide bond Glycoprotein Host cell membrane Host membrane Host-virus interaction Hydrogen ion transport Inhibition of host autophagy by virus Ion channel Ion transport Lipoprotein Membrane Palmitate Phosphoprotein Signal-anchor Transmembrane Transmembrane helix Transport Viral ion channel Virion MSLPTEVETP MSLPTEVETPTRNEWGCRCNDSSDHITIAAKFIGILHLILWILDRLFFKCIYRRLKYGPKRGPSTEGVPDSMREEYRQKQQNAADVDDGHFVNIELE
protein complex oligomerization suppression by virus of host autophagy virus-mediated pore formation in host cell membrane
host cell plasma membrane; membrane; virion membrane
monoatomic ion channel activity proton transmembrane transporter activity
Influenza A virus )
Alternative splicing Disulfide bond Glycoprotein Host cell membrane Host membrane Host-virus interaction Hydrogen ion transport Inhibition of host autophagy by virus Ion channel Ion transport Lipoprotein Membrane Palmitate Phosphoprotein Reference proteome Signal-anchor Transmembrane Transmembrane helix Transport Viral ion channel Virion
MSLLTEVETP
MSLLTEVETPIRNEWGCRCNDSSDPLVIAANIIGILHLILWILDRLFFKCIYRRFKYGLKRGPSTEGVPESMREEYRKEQQNAVDVDDGHFVNIELE
protein complex oligomerization suppression by virus of host autophagy virus-mediated pore formation in host cell membrane host cell plasma membrane; membrane; virion membrane monoatomic ion channel activity proton transmembrane transporter activity Influenza A virus )Alternative splicing Disulfide bond Glycoprotein Host cell membrane Host membrane Host-virus interaction Hydrogen ion transport Inhibition of host autophagy by virus Ion channel Ion transport Lipoprotein Membrane Palmitate Phosphoprotein Reference proteome Signal-anchor Transmembrane Transmembrane helix Transport Viral ion channel Virion MSLLTEVETP MSLLTEVETPIRNEWGCRCNDSSDPLVIAANIIGILHLILWILDRLFFKCIYRRFKYGLKRGPSTEGVPESMREEYRKEQQNAVDVDDGHFVNIELE
anatomical structure morphogenesis cell cycle extrinsic apoptotic signaling pathway Golgi to plasma membrane protein transport hepatocyte apoptotic process intermediate filament cytoskeleton organization negative regulation of apoptotic process tumor necrosis factor-mediated signaling pathway
adherens junction; cell periphery; centriolar satellite; cytoplasm; cytoskeleton; cytosol; extracellular exosome; intermediate filament; keratin filament; microtubule organizing center; nuclear matrix; nucleolus; perinuclear region of cytoplasm
cadherin binding involved in cell-cell adhesion RNA binding scaffold protein binding structural molecule activity
Homo sapiens
Acetylation Cell cycle Coiled coil Cytoplasm Direct protein sequencing Disease variant Glycoprotein Host-virus interaction Intermediate filament Isopeptide bond Keratin Methylation Nucleus Phosphoprotein Reference proteome Ubl conjugation
MSFTTRSTFS
MSFTTRSTFSTNYRSLGSVQAPSYGARPVSSAASVYAGAGGSGSRISVSRSTSFRGGMGSGGLATGIAGGLAGMGGIQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQVRDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEIATYRRLLEDGEDFNLGDALDSSNSMQTIQKTTTRRIVDGKVVSETNDTKVLRH
anatomical structure morphogenesis cell cycle extrinsic apoptotic signaling pathway Golgi to plasma membrane protein transport hepatocyte apoptotic process intermediate filament cytoskeleton organization negative regulation of apoptotic process tumor necrosis factor-mediated signaling pathway adherens junction; cell periphery; centriolar satellite; cytoplasm; cytoskeleton; cytosol; extracellular exosome; intermediate filament; keratin filament; microtubule organizing center; nuclear matrix; nucleolus; perinuclear region of cytoplasm cadherin binding involved in cell-cell adhesion RNA binding scaffold protein binding structural molecule activity Homo sapiens Acetylation Cell cycle Coiled coil Cytoplasm Direct protein sequencing Disease variant Glycoprotein Host-virus interaction Intermediate filament Isopeptide bond Keratin Methylation Nucleus Phosphoprotein Reference proteome Ubl conjugation MSFTTRSTFS MSFTTRSTFSTNYRSLGSVQAPSYGARPVSSAASVYAGAGGSGSRISVSRSTSFRGGMGSGGLATGIAGGLAGMGGIQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQVRDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEIATYRRLLEDGEDFNLGDALDSSNSMQTIQKTTTRRIVDGKVVSETNDTKVLRH
extrinsic apoptotic signaling pathway Golgi to plasma membrane protein transport hepatocyte apoptotic process intermediate filament cytoskeleton organization negative regulation of apoptotic process tumor necrosis factor-mediated signaling pathway
cell periphery; centriolar satellite; cytoplasm; cytoskeleton; cytosol; external side of plasma membrane; extracellular space; intermediate filament; keratin filament; microtubule organizing center; nuclear matrix; nucleolus; perinuclear region of cytoplasm; protein-containing complex
scaffold protein binding structural molecule activity
Mus musculus
Acetylation Coiled coil Cytoplasm Glycoprotein Intermediate filament Isopeptide bond Keratin Methylation Nucleus Phosphoprotein Reference proteome Ubl conjugation
MSFTTRSTTF
MSFTTRSTTFSTNYRSLGSVRTPSQRVRPASSAASVYAGAGGSGSRISVSRSVWGGSVGSAGLAGMGGIQTEKETMQDLNDRLASYLDKVKSLETENRRLESKIREHLEKKGPQGVRDWGHYFKIIEDLRAQIFANSVDNARIVLQIDNARLAADDFRVKYETELAMRQSVESDIHGLRKVVDDTNITRLQLETEIEALKEELLFMKKNHEEEVQGLEAQIASSGLTVEVDAPKSQDLSKIMADIRAQYEALAQKNREELDKYWSQQIEESTTVVTTKSAEIRDAETTLTELRRTLQTLEIDLDSMKNQNINLENSLGDVEARYKAQMEQLNGVLLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEIATYRRLLEDGEDFSLNDALDSSNSMQTVQKTTTRKIVDGRVVSETNDTRVLRH
extrinsic apoptotic signaling pathway Golgi to plasma membrane protein transport hepatocyte apoptotic process intermediate filament cytoskeleton organization negative regulation of apoptotic process tumor necrosis factor-mediated signaling pathway cell periphery; centriolar satellite; cytoplasm; cytoskeleton; cytosol; external side of plasma membrane; extracellular space; intermediate filament; keratin filament; microtubule organizing center; nuclear matrix; nucleolus; perinuclear region of cytoplasm; protein-containing complex scaffold protein binding structural molecule activity Mus musculus Acetylation Coiled coil Cytoplasm Glycoprotein Intermediate filament Isopeptide bond Keratin Methylation Nucleus Phosphoprotein Reference proteome Ubl conjugation MSFTTRSTTF MSFTTRSTTFSTNYRSLGSVRTPSQRVRPASSAASVYAGAGGSGSRISVSRSVWGGSVGSAGLAGMGGIQTEKETMQDLNDRLASYLDKVKSLETENRRLESKIREHLEKKGPQGVRDWGHYFKIIEDLRAQIFANSVDNARIVLQIDNARLAADDFRVKYETELAMRQSVESDIHGLRKVVDDTNITRLQLETEIEALKEELLFMKKNHEEEVQGLEAQIASSGLTVEVDAPKSQDLSKIMADIRAQYEALAQKNREELDKYWSQQIEESTTVVTTKSAEIRDAETTLTELRRTLQTLEIDLDSMKNQNINLENSLGDVEARYKAQMEQLNGVLLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEIATYRRLLEDGEDFSLNDALDSSNSMQTVQKTTTRKIVDGRVVSETNDTRVLRH
cell differentiation involved in embryonic placenta development extrinsic apoptotic signaling pathway hepatocyte apoptotic process response to hydrostatic pressure response to other organism sarcomere organization tumor necrosis factor-mediated signaling pathway
apicolateral plasma membrane; cell-cell junction; costamere; cytoplasm; cytosol; dystrophin-associated glycoprotein complex; extracellular exosome; intermediate filament; intermediate filament cytoskeleton; keratin filament; nuclear matrix; nucleoplasm; nucleus; sarcolemma; Z disc
protein-containing complex binding scaffold protein binding
Homo sapiens
3D-structure Acetylation Alternative splicing Coiled coil Cytoplasm Direct protein sequencing Disease variant Glycoprotein Host-virus interaction Intermediate filament Isopeptide bond Keratin Methylation Nucleus Phosphoprotein Reference proteome Ubl conjugation
MSIRVTQKSY
MSIRVTQKSYKVSTSGPRAFSSRSYTSGPGSRISSSSFSRVGSSNFRGGLGGGYGGASGMGGITAVTVNQSLLSPLVLEVDPNIQAVRTQEKEQIKTLNNKFASFIDKVRFLEQQNKMLETKWSLLQQQKTARSNMDNMFESYINNLRRQLETLGQEKLKLEAELGNMQGLVEDFKNKYEDEINKRTEMENEFVLIKKDVDEAYMNKVELESRLEGLTDEINFLRQLYEEEIRELQSQISDTSVVLSMDNSRSLDMDSIIAEVKAQYEDIANRSRAEAESMYQIKYEELQSLAGKHGDDLRRTKTEISEMNRNISRLQAEIEGLKGQRASLEAAIADAEQRGELAIKDANAKLSELEAALQRAKQDMARQLREYQELMNVKLALDIEIATYRKLLEGEESRLESGMQNMSIHTKTTSGYAGGLSSAYGGLTSPGLSYSLGSSFGSGAGSSSFSRTSSSRAVVVKKIETRDGKLVSESSDVLPK
cell differentiation involved in embryonic placenta development extrinsic apoptotic signaling pathway hepatocyte apoptotic process response to hydrostatic pressure response to other organism sarcomere organization tumor necrosis factor-mediated signaling pathway apicolateral plasma membrane; cell-cell junction; costamere; cytoplasm; cytosol; dystrophin-associated glycoprotein complex; extracellular exosome; intermediate filament; intermediate filament cytoskeleton; keratin filament; nuclear matrix; nucleoplasm; nucleus; sarcolemma; Z disc protein-containing complex binding scaffold protein binding Homo sapiens 3D-structure Acetylation Alternative splicing Coiled coil Cytoplasm Direct protein sequencing Disease variant Glycoprotein Host-virus interaction Intermediate filament Isopeptide bond Keratin Methylation Nucleus Phosphoprotein Reference proteome Ubl conjugation MSIRVTQKSY MSIRVTQKSYKVSTSGPRAFSSRSYTSGPGSRISSSSFSRVGSSNFRGGLGGGYGGASGMGGITAVTVNQSLLSPLVLEVDPNIQAVRTQEKEQIKTLNNKFASFIDKVRFLEQQNKMLETKWSLLQQQKTARSNMDNMFESYINNLRRQLETLGQEKLKLEAELGNMQGLVEDFKNKYEDEINKRTEMENEFVLIKKDVDEAYMNKVELESRLEGLTDEINFLRQLYEEEIRELQSQISDTSVVLSMDNSRSLDMDSIIAEVKAQYEDIANRSRAEAESMYQIKYEELQSLAGKHGDDLRRTKTEISEMNRNISRLQAEIEGLKGQRASLEAAIADAEQRGELAIKDANAKLSELEAALQRAKQDMARQLREYQELMNVKLALDIEIATYRKLLEGEESRLESGMQNMSIHTKTTSGYAGGLSSAYGGLTSPGLSYSLGSSFGSGAGSSSFSRTSSSRAVVVKKIETRDGKLVSESSDVLPK
isoleucine biosynthetic process valine biosynthetic process
cytosol
2 iron, 2 sulfur cluster binding 4 iron, 4 sulfur cluster binding dihydroxy-acid dehydratase activity hydro-lyase activity iron-sulfur cluster binding magnesium ion binding
Escherichia coli
2Fe-2S Amino-acid biosynthesis Branched-chain amino acid biosynthesis Direct protein sequencing Iron Iron-sulfur Lyase Magnesium Metal-binding Reference proteome
MPKYRSATTT
MPKYRSATTTHGRNMAGARALWRATGMTDADFGKPIIAVVNSFTQFVPGHVHLRDLGKLVAEQIEAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQIIKLDLVDAMIQGADPKVSDSQSDQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKQLFLNAGKRIVELTKRYYEQNDESALPRNIASKAAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVIGILGELDRAGLLNRDVKNVLGLTLPQTLEQYDVMLTQDDAVKNMFRAGPAGIRTTQAFSQDCRWDTLDDDRANGCIRSLEHAYSKDGGLAVLYGNFAENGCIVKTAGVDDSILKFTGPAKVYESQDDAVEAILGGKVVAGDVVVIRYEGPKGGPGMQEMLYPTSFLKSMGLGKACALITDGRFSGGTSGLSIGHVSPEAASGGSIGLIEDGDLIAIDIPNRGIQLQVSDAELAARREAQDARGDKAWTPKNRERQVSFALRAYASLATSADKGAVRDKSKLGG
isoleucine biosynthetic process valine biosynthetic process cytosol 2 iron, 2 sulfur cluster binding 4 iron, 4 sulfur cluster binding dihydroxy-acid dehydratase activity hydro-lyase activity iron-sulfur cluster binding magnesium ion binding Escherichia coli 2Fe-2S Amino-acid biosynthesis Branched-chain amino acid biosynthesis Direct protein sequencing Iron Iron-sulfur Lyase Magnesium Metal-binding Reference proteome MPKYRSATTT MPKYRSATTTHGRNMAGARALWRATGMTDADFGKPIIAVVNSFTQFVPGHVHLRDLGKLVAEQIEAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQIIKLDLVDAMIQGADPKVSDSQSDQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKQLFLNAGKRIVELTKRYYEQNDESALPRNIASKAAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVIGILGELDRAGLLNRDVKNVLGLTLPQTLEQYDVMLTQDDAVKNMFRAGPAGIRTTQAFSQDCRWDTLDDDRANGCIRSLEHAYSKDGGLAVLYGNFAENGCIVKTAGVDDSILKFTGPAKVYESQDDAVEAILGGKVVAGDVVVIRYEGPKGGPGMQEMLYPTSFLKSMGLGKACALITDGRFSGGTSGLSIGHVSPEAASGGSIGLIEDGDLIAIDIPNRGIQLQVSDAELAARREAQDARGDKAWTPKNRERQVSFALRAYASLATSADKGAVRDKSKLGG
isoleucine biosynthetic process pantothenate biosynthetic process valine biosynthetic process
cytosol; protein-containing complex
2-dehydropantoate 2-reductase activity identical protein binding ketol-acid reductoisomerase activity magnesium ion binding NADP binding
Escherichia coli
3D-structure Amino-acid biosynthesis Branched-chain amino acid biosynthesis Cytoplasm Direct protein sequencing Magnesium Metal-binding NADP Oxidoreductase Reference proteome Repeat
MANYFNTLNL
MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVINLTPDKQHSDVVRTVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVEEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREETGKTAFETAPQYEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGKAIPEGAVDNGQLRDVNEAIRSHAIEQVGKKLRGYMTDMKRIAVAG
isoleucine biosynthetic process pantothenate biosynthetic process valine biosynthetic process cytosol; protein-containing complex 2-dehydropantoate 2-reductase activity identical protein binding ketol-acid reductoisomerase activity magnesium ion binding NADP binding Escherichia coli 3D-structure Amino-acid biosynthesis Branched-chain amino acid biosynthesis Cytoplasm Direct protein sequencing Magnesium Metal-binding NADP Oxidoreductase Reference proteome Repeat MANYFNTLNL MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVINLTPDKQHSDVVRTVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVEEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREETGKTAFETAPQYEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGKAIPEGAVDNGQLRDVNEAIRSHAIEQVGKKLRGYMTDMKRIAVAG
carbohydrate metabolic process viral budding from plasma membrane
host cell plasma membrane; membrane; virion membrane
exo-alpha-(2->3)-sialidase activity exo-alpha-(2->6)-sialidase activity exo-alpha-(2->8)-sialidase activity metal ion binding
Influenza A virus
3D-structure Calcium Disulfide bond Glycoprotein Glycosidase Host cell membrane Host membrane Hydrolase Membrane Metal-binding Signal-anchor Transmembrane Transmembrane helix Virion
MNPNQKILCT
MNPNQKILCTSATALVIGTIAVLIGIVNLGLNIGLHLKPSCNCSRSQPEATNASQTIINNYYNETNITQISNTNIQVEERASREFNNLTKGLCTINSWHIYGKDNAVRIGEDSDVLVTREPYVSCDPDECRFYALSQGTTIRGKHSNGTIHDRSQYRDLISWPLSSPPTVYNSRVECIGWSSTSCHDGRARMSICISGPNNNASAVIWYNRRPVTEINTWARNILRTQESECVCQNGVCPVVFTDGSATGPAETRIYYFKEGKILKWEPLTGTAKHIEECSCYGEQAGVTCTCRDNWQGSNRPVIQIDPVAMTHTSQYICSPVLTDNPRPNDPTVGKCNDPYPGNNNNGVKGFSYLDGGNTWLGRTISIASRSGYEMLKVPNALTDDRSKPTQGQTIVLNTDWSGYSGSFMDYWAEGECYRACFYVELIRGRPKEDKVWWTSNSIVSMCSSTEFLGQWNWPDGAKIEYFL
carbohydrate metabolic process viral budding from plasma membrane host cell plasma membrane; membrane; virion membrane exo-alpha-(2->3)-sialidase activity exo-alpha-(2->6)-sialidase activity exo-alpha-(2->8)-sialidase activity metal ion binding Influenza A virus 3D-structure Calcium Disulfide bond Glycoprotein Glycosidase Host cell membrane Host membrane Hydrolase Membrane Metal-binding Signal-anchor Transmembrane Transmembrane helix Virion MNPNQKILCT MNPNQKILCTSATALVIGTIAVLIGIVNLGLNIGLHLKPSCNCSRSQPEATNASQTIINNYYNETNITQISNTNIQVEERASREFNNLTKGLCTINSWHIYGKDNAVRIGEDSDVLVTREPYVSCDPDECRFYALSQGTTIRGKHSNGTIHDRSQYRDLISWPLSSPPTVYNSRVECIGWSSTSCHDGRARMSICISGPNNNASAVIWYNRRPVTEINTWARNILRTQESECVCQNGVCPVVFTDGSATGPAETRIYYFKEGKILKWEPLTGTAKHIEECSCYGEQAGVTCTCRDNWQGSNRPVIQIDPVAMTHTSQYICSPVLTDNPRPNDPTVGKCNDPYPGNNNNGVKGFSYLDGGNTWLGRTISIASRSGYEMLKVPNALTDDRSKPTQGQTIVLNTDWSGYSGSFMDYWAEGECYRACFYVELIRGRPKEDKVWWTSNSIVSMCSSTEFLGQWNWPDGAKIEYFL
carbohydrate metabolic process glucuronoside catabolic process
cytosol; protein-containing complex
beta-glucuronidase activity carbohydrate binding identical protein binding
Escherichia coli
3D-structure Direct protein sequencing Glycosidase Hydrolase Reference proteome
MLRPVETPTR
MLRPVETPTREIKKLDGLWAFSLDRENCGIDQRWWESALQESRAIAVPGSFNDQFADADIRNYAGNVWYQREVFIPKGWAGQRIVLRFDAVTHYGKVWVNNQEVMEHQGGYTPFEADVTPYVIAGKSVRITVCVNNELNWQTIPPGMVITDENGKKKQSYFHDFFNYAGIHRSVMLYTTPNTWVDDITVVTHVAQDCNHASVDWQVVANGDVSVELRDADQQVVATGQGTSGTLQVVNPHLWQPGEGYLYELCVTAKSQTECDIYPLRVGIRSVAVKGEQFLINHKPFYFTGFGRHEDADLRGKGFDNVLMVHDHALMDWIGANSYRTSHYPYAEEMLDWADEHGIVVIDETAAVGFNLSLGIGFEAGNKPKELYSEEAVNGETQQAHLQAIKELIARDKNHPSVVMWSIANEPDTRPQGAREYFAPLAEATRKLDPTRPITCVNVMFCDAHTDTISDLFDVLCLNRYYGWYVQSGDLETAEKVLEKELLAWQEKLHQPIIITEYGVDTLAGLHSMYTDMWSEEYQCAWLDMYHRVFDRVSAVVGEQVWNFADFATSQGILRVGGNKKGIFTRDRKPKSAAFLLQKRWTGMNFGEKPQQGGKQ
carbohydrate metabolic process glucuronoside catabolic process cytosol; protein-containing complex beta-glucuronidase activity carbohydrate binding identical protein binding Escherichia coli 3D-structure Direct protein sequencing Glycosidase Hydrolase Reference proteome MLRPVETPTR MLRPVETPTREIKKLDGLWAFSLDRENCGIDQRWWESALQESRAIAVPGSFNDQFADADIRNYAGNVWYQREVFIPKGWAGQRIVLRFDAVTHYGKVWVNNQEVMEHQGGYTPFEADVTPYVIAGKSVRITVCVNNELNWQTIPPGMVITDENGKKKQSYFHDFFNYAGIHRSVMLYTTPNTWVDDITVVTHVAQDCNHASVDWQVVANGDVSVELRDADQQVVATGQGTSGTLQVVNPHLWQPGEGYLYELCVTAKSQTECDIYPLRVGIRSVAVKGEQFLINHKPFYFTGFGRHEDADLRGKGFDNVLMVHDHALMDWIGANSYRTSHYPYAEEMLDWADEHGIVVIDETAAVGFNLSLGIGFEAGNKPKELYSEEAVNGETQQAHLQAIKELIARDKNHPSVVMWSIANEPDTRPQGAREYFAPLAEATRKLDPTRPITCVNVMFCDAHTDTISDLFDVLCLNRYYGWYVQSGDLETAEKVLEKELLAWQEKLHQPIIITEYGVDTLAGLHSMYTDMWSEEYQCAWLDMYHRVFDRVSAVVGEQVWNFADFATSQGILRVGGNKKGIFTRDRKPKSAAFLLQKRWTGMNFGEKPQQGGKQ
proteolysis
extracellular region
metal ion binding metalloendopeptidase activity
Bacillus cereus
3D-structure Calcium Direct protein sequencing Hydrolase Metal-binding Metalloprotease Protease Secreted Signal Zinc
MKKKSLALVL
MKKKSLALVLATGMAVTTFGGTGSAFADSKNVLSTKKYNETVQSPEFISGDLTEATGKKAESVVFDYLNAAKGDYKLGEKSAQDSFKVKQVKKDAVTDSTVVRMQQVYEGVPVWGSTQVAHVSKDGSLKVLSGTVAPDLDKKEKLKNKNKIEGAKAIEIAQQDLGVTPKYEVEPKADLYVYQNGEETTYAYVVNLNFLDPSPGNYYYFIEADSGKVLNKFNTIDHVTNDDKSPVKQEAPKQDAKAVVKPVTGTNKVGTGKGVLGDTKSLNTTLSGSSYYLQDNTRGATIFTYDAKNRSTLPGTLWADADNVFNAAYDAAAVDAHYYAGKTYDYYKATFNRNSINDAGAPLKSTVHYGSNYNNAFWNGSQMVYGDGDGVTFTSLSGGIDVIGHELTHAVTENSSNLIYQNESGALNEAISDIFGTLVEFYDNRNPDWEIGEDIYTPGKAGDALRSMSDPTKYGDPDHYSKRYTGSSDNGGVHTNSGIINKQAYLLANGGTHYGVTVTGIGKDKLGAIYYRANTQYFTQSTTFSQARAGAVQAAADLYGANSAEVAAVKQSFSAVGVN
proteolysis extracellular region metal ion binding metalloendopeptidase activity Bacillus cereus3D-structure Calcium Direct protein sequencing Hydrolase Metal-binding Metalloprotease Protease Secreted Signal Zinc MKKKSLALVL MKKKSLALVLATGMAVTTFGGTGSAFADSKNVLSTKKYNETVQSPEFISGDLTEATGKKAESVVFDYLNAAKGDYKLGEKSAQDSFKVKQVKKDAVTDSTVVRMQQVYEGVPVWGSTQVAHVSKDGSLKVLSGTVAPDLDKKEKLKNKNKIEGAKAIEIAQQDLGVTPKYEVEPKADLYVYQNGEETTYAYVVNLNFLDPSPGNYYYFIEADSGKVLNKFNTIDHVTNDDKSPVKQEAPKQDAKAVVKPVTGTNKVGTGKGVLGDTKSLNTTLSGSSYYLQDNTRGATIFTYDAKNRSTLPGTLWADADNVFNAAYDAAAVDAHYYAGKTYDYYKATFNRNSINDAGAPLKSTVHYGSNYNNAFWNGSQMVYGDGDGVTFTSLSGGIDVIGHELTHAVTENSSNLIYQNESGALNEAISDIFGTLVEFYDNRNPDWEIGEDIYTPGKAGDALRSMSDPTKYGDPDHYSKRYTGSSDNGGVHTNSGIINKQAYLLANGGTHYGVTVTGIGKDKLGAIYYRANTQYFTQSTTFSQARAGAVQAAADLYGANSAEVAAVKQSFSAVGVN
DNA-templated transcription
virion component
ATP binding ATP-dependent chromatin remodeler activity DNA binding ribonucleoside triphosphate phosphatase activity
Vaccinia virus )
ATP-binding DNA-binding Hydrolase Late protein Nucleotide-binding Reference proteome Transcription Virion
MSKSHAAYID
MSKSHAAYIDYALRRTTNMPVEMMGSDVVRLKDYQHFVARVFLGLDSMHSLLLFHETGVGKTMTTVYILKHLKDIYTNWAIILLVKKALIEDPWMNTILRYAPEITKDCIFINYDDQNFRNKFFTNIKTINSKSRICVIIDECHNFISKSLIKEDGKIRPTRSVYNFLSKTIALKNHKMICLSATPIVNSVQEFTMLVNLLRPGSLQHQSLFENKRLVDEKELVSKLGGLCSYIVNNEFSIFDDVEGSASFAKKTVLMRYVNMSKKQEEIYQKAKLAEIKTGISSFRILRRMATTFTFDSFPERQNRDPGEYAQEIATLYNDFKNSLRDREFSKSALDTFKRGELLGGDASAADISLFTELKEKSVKFIDVCLGILASHGKCLVFEPFVNQSGIEILLLYFKVFGISNIEFSSRTKDTRIKAVAEFNQESNTNGECIKTCVFSSSGGEGISFFSINDIFILDMTWNEASLRQIVGRAIRLNSHVLTPPERRYVNVHFIMARLSNGMPTVDEDLFEIIQSKSKEFVQLFRVFKHTSLEWIHANEKDFSPIDNESGWKTLVSRAIDLSSNKNITNKLIEGTNIWYSNSNRLMSINRGFKGVDGRVYDVDGNYLHDMPDNPVIKIHDGKLIYIF
DNA-templated transcription virion component ATP binding ATP-dependent chromatin remodeler activity DNA binding ribonucleoside triphosphate phosphatase activity Vaccinia virus )ATP-binding DNA-binding Hydrolase Late protein Nucleotide-binding Reference proteome Transcription Virion MSKSHAAYID MSKSHAAYIDYALRRTTNMPVEMMGSDVVRLKDYQHFVARVFLGLDSMHSLLLFHETGVGKTMTTVYILKHLKDIYTNWAIILLVKKALIEDPWMNTILRYAPEITKDCIFINYDDQNFRNKFFTNIKTINSKSRICVIIDECHNFISKSLIKEDGKIRPTRSVYNFLSKTIALKNHKMICLSATPIVNSVQEFTMLVNLLRPGSLQHQSLFENKRLVDEKELVSKLGGLCSYIVNNEFSIFDDVEGSASFAKKTVLMRYVNMSKKQEEIYQKAKLAEIKTGISSFRILRRMATTFTFDSFPERQNRDPGEYAQEIATLYNDFKNSLRDREFSKSALDTFKRGELLGGDASAADISLFTELKEKSVKFIDVCLGILASHGKCLVFEPFVNQSGIEILLLYFKVFGISNIEFSSRTKDTRIKAVAEFNQESNTNGECIKTCVFSSSGGEGISFFSINDIFILDMTWNEASLRQIVGRAIRLNSHVLTPPERRYVNVHFIMARLSNGMPTVDEDLFEIIQSKSKEFVQLFRVFKHTSLEWIHANEKDFSPIDNESGWKTLVSRAIDLSSNKNITNKLIEGTNIWYSNSNRLMSINRGFKGVDGRVYDVDGNYLHDMPDNPVIKIHDGKLIYIF
apoptotic process involved in morphogenesis cellular response to gamma radiation lens development in camera-type eye muscle organ development negative regulation of amyloid fibril formation negative regulation of apoptotic process negative regulation of DNA-templated transcription negative regulation of gene expression negative regulation of intracellular transport negative regulation of protein-containing complex assembly protein stabilization response to hydrogen peroxide response to hypoxia tubulin complex assembly
cytoplasm; cytosol; extracellular region; lysosome; mitochondrion; nucleus; plasma membrane; protein-containing complex; Z disc
amyloid-beta binding metal ion binding protein homodimerization activity protein-containing complex binding structural constituent of eye lens unfolded protein binding
Mesocricetus auratus
Acetylation Chaperone Cytoplasm Eye lens protein Glycoprotein Lysosome Metal-binding Methylation Nucleus Phosphoprotein Reference proteome Secreted Zinc
MDIAIHHPWI
MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFSTATSLSPFYLRPPSFLRAPSWIDTGLSEMRMEKDRFSVNLDVKHFSPEELKVKVLGDVVEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQASGPERTIPITREEKPAVTAAPKK
apoptotic process involved in morphogenesis cellular response to gamma radiation lens development in camera-type eye muscle organ development negative regulation of amyloid fibril formation negative regulation of apoptotic process negative regulation of DNA-templated transcription negative regulation of gene expression negative regulation of intracellular transport negative regulation of protein-containing complex assembly protein stabilization response to hydrogen peroxide response to hypoxia tubulin complex assembly cytoplasm; cytosol; extracellular region; lysosome; mitochondrion; nucleus; plasma membrane; protein-containing complex; Z disc amyloid-beta binding metal ion binding protein homodimerization activity protein-containing complex binding structural constituent of eye lens unfolded protein binding Mesocricetus auratus Acetylation Chaperone Cytoplasm Eye lens protein Glycoprotein Lysosome Metal-binding Methylation Nucleus Phosphoprotein Reference proteome Secreted Zinc MDIAIHHPWI MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFSTATSLSPFYLRPPSFLRAPSWIDTGLSEMRMEKDRFSVNLDVKHFSPEELKVKVLGDVVEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQASGPERTIPITREEKPAVTAAPKK
lens development in camera-type eye negative regulation of cytokine production negative regulation of ERK1 and ERK2 cascade negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction negative regulation of TOR signaling phagocytosis positive regulation of anoikis regulation of autophagy visual perception
cytoplasm; nucleus
structural constituent of eye lens
Homo sapiens
Acetylation Alternative initiation Cataract Direct protein sequencing Disease variant Eye lens protein Glutathionylation Methylation Oxidation Reference proteome Repeat
METQAEQQEL
METQAEQQELETLPTTKMAQTNPTPGSLGPWKITIYDQENFQGKRMEFTSSCPNVSERSFDNVRSLKVESGAWIGYEHTSFCGQQFILERGEYPRWDAWSGSNAYHIERLMSFRPICSANHKESKMTIFEKENFIGRQWEISDDYPSLQAMGWFNNEVGSMKIQSGAWVCYQYPGYRGYQYILECDHHGGDYKHWREWGSHAQTSQIQSIRRIQQ
lens development in camera-type eye negative regulation of cytokine production negative regulation of ERK1 and ERK2 cascade negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction negative regulation of TOR signaling phagocytosis positive regulation of anoikis regulation of autophagy visual perception cytoplasm; nucleus structural constituent of eye lens Homo sapiens Acetylation Alternative initiation Cataract Direct protein sequencing Disease variant Eye lens protein Glutathionylation Methylation Oxidation Reference proteome Repeat METQAEQQEL METQAEQQELETLPTTKMAQTNPTPGSLGPWKITIYDQENFQGKRMEFTSSCPNVSERSFDNVRSLKVESGAWIGYEHTSFCGQQFILERGEYPRWDAWSGSNAYHIERLMSFRPICSANHKESKMTIFEKENFIGRQWEISDDYPSLQAMGWFNNEVGSMKIQSGAWVCYQYPGYRGYQYILECDHHGGDYKHWREWGSHAQTSQIQSIRRIQQ
calcium ion transport lactation negative regulation of cysteine-type endopeptidase activity
extracellular region; extracellular space
calcium ion binding cysteine-type endopeptidase inhibitor activity enzyme inhibitor activity
Homo sapiens
Direct protein sequencing Milk protein Phosphoprotein Reference proteome Secreted Signal
MKVLILACLV
MKVLILACLVALALARETIESLSSSEESITEYKQKVEKVKHEDQQQGEDEHQDKIYPSFQPQPLIYPFVEPIPYGFLPQNILPLAQPAVVLPVPQPEIMEVPKAKDTVYTKGRVMPVLKSPTIPFFDPQIPKLTDLENLHLPLPLLQPLMQQVPQPIPQTLALPPQPLWSVPQPKVLPIPQQVVPYPQRAVPVQALLLNQELLLNPTHQIYPVTQPLAPVHNPISV
calcium ion transport lactation negative regulation of cysteine-type endopeptidase activity extracellular region; extracellular space calcium ion binding cysteine-type endopeptidase inhibitor activity enzyme inhibitor activity Homo sapiens Direct protein sequencing Milk protein Phosphoprotein Reference proteome Secreted Signal MKVLILACLV MKVLILACLVALALARETIESLSSSEESITEYKQKVEKVKHEDQQQGEDEHQDKIYPSFQPQPLIYPFVEPIPYGFLPQNILPLAQPAVVLPVPQPEIMEVPKAKDTVYTKGRVMPVLKSPTIPFFDPQIPKLTDLENLHLPLPLLQPLMQQVPQPIPQTLALPPQPLWSVPQPKVLPIPQQVVPYPQRAVPVQALLLNQELLLNPTHQIYPVTQPLAPVHNPISV
DNA damage response double-strand break repair recombinational interstrand cross-link repair recombinational repair response to ionizing radiation response to radiation response to UV response to X-ray SOS response
bacterial nucleoid; cytosol
ATP binding
Escherichia coli
ATP-binding Cytoplasm DNA damage DNA repair Nucleotide-binding Reference proteome
MLAQLTISNF
MLAQLTISNFAIVRELEIDFHSGMTVITGETGAGKSIAIDALGLCLGGRAEADMVRTGAARADLCARFSLKDTPAALRWLEENQLEDGHECLLRRVISSDGRSRGFINGTAVPLSQLRELGQLLIQIHGQHAHQLLTKPEHQKFLLDGYANETSLLQEMTARYQLWHQSCRDLAHHQQLSQERAARAELLQYQLKELNEFNPQPGEFEQIDEEYKRLANSGQLLTTSQNALALMADGEDANLQSQLYTAKQLVSELIGMDSKLSGVLDMLEEATIQIAEASDELRHYCDRLDLDPNRLFELEQRISKQISLARKHHVSPEALPQYYQSLLEEQQQLDDQADSQETLALAVTKHHQQALEIARALHQQRQQYAEELAQLITDSMHALSMPHGQFTIDVKFDEHHLGADGADRIEFRVTTNPGQPMQPIAKVASGGELSRIALAIQVITARKMETPALIFDEVDVGISGPTAAVVGKLLRQLGESTQVMCVTHLPQVAGCGHQHYFVSKETDGAMTETHMQSLNKKARLQELARLLGGSEVTRNTLANAKELLAA
DNA damage response double-strand break repair recombinational interstrand cross-link repair recombinational repair response to ionizing radiation response to radiation response to UV response to X-ray SOS response bacterial nucleoid; cytosol ATP binding Escherichia coli ATP-binding Cytoplasm DNA damage DNA repair Nucleotide-binding Reference proteome MLAQLTISNF MLAQLTISNFAIVRELEIDFHSGMTVITGETGAGKSIAIDALGLCLGGRAEADMVRTGAARADLCARFSLKDTPAALRWLEENQLEDGHECLLRRVISSDGRSRGFINGTAVPLSQLRELGQLLIQIHGQHAHQLLTKPEHQKFLLDGYANETSLLQEMTARYQLWHQSCRDLAHHQQLSQERAARAELLQYQLKELNEFNPQPGEFEQIDEEYKRLANSGQLLTTSQNALALMADGEDANLQSQLYTAKQLVSELIGMDSKLSGVLDMLEEATIQIAEASDELRHYCDRLDLDPNRLFELEQRISKQISLARKHHVSPEALPQYYQSLLEEQQQLDDQADSQETLALAVTKHHQQALEIARALHQQRQQYAEELAQLITDSMHALSMPHGQFTIDVKFDEHHLGADGADRIEFRVTTNPGQPMQPIAKVASGGELSRIALAIQVITARKMETPALIFDEVDVGISGPTAAVVGKLLRQLGESTQVMCVTHLPQVAGCGHQHYFVSKETDGAMTETHMQSLNKKARLQELARLLGGSEVTRNTLANAKELLAA
colicin transport enterobactin transport ferric-enterobactin import into cell intracellular iron ion homeostasis siderophore transmembrane transport siderophore-dependent iron import into cell
cell envelope; cell outer membrane; membrane; transmembrane transporter complex
colicin transmembrane transporter activity enterobactin binding enterobactin transmembrane transporter activity ferric-enterobactin transmembrane transporter activity ligand-gated channel activity protein domain specific binding siderophore uptake transmembrane transporter activity signaling receptor activity
Escherichia coli
3D-structure Cell outer membrane Ion transport Iron Iron transport Membrane Receptor Reference proteome Signal TonB box Transmembrane Transmembrane beta strand Transport
MNKKIHSLAL
MNKKIHSLALLVNLGIYGVAQAQEPTDTPVSHDDTIVVTAAEQNLQAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAAARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGDEFSFRLYGNLDKTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWDFAPLQSLELEAGYSRQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYALTWNGGWDNGVTTSNWVQYEHTRNSRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNLPIDFLVNQTLTLGTEWNQQRMKDLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAEIFSLFAENNMELTDSTIVTPGLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYILYSKGQGCYASAGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIEAGYVAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSENKTTGDRLSIIPEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIAGAGAYTYNEPGRTWYMSVNTHF
colicin transport enterobactin transport ferric-enterobactin import into cell intracellular iron ion homeostasis siderophore transmembrane transport siderophore-dependent iron import into cell cell envelope; cell outer membrane; membrane; transmembrane transporter complex colicin transmembrane transporter activity enterobactin binding enterobactin transmembrane transporter activity ferric-enterobactin transmembrane transporter activity ligand-gated channel activity protein domain specific binding siderophore uptake transmembrane transporter activity signaling receptor activity Escherichia coli 3D-structure Cell outer membrane Ion transport Iron Iron transport Membrane Receptor Reference proteome Signal TonB box Transmembrane Transmembrane beta strand Transport MNKKIHSLAL MNKKIHSLALLVNLGIYGVAQAQEPTDTPVSHDDTIVVTAAEQNLQAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAAARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGDEFSFRLYGNLDKTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWDFAPLQSLELEAGYSRQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYALTWNGGWDNGVTTSNWVQYEHTRNSRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNLPIDFLVNQTLTLGTEWNQQRMKDLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAEIFSLFAENNMELTDSTIVTPGLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYILYSKGQGCYASAGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIEAGYVAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSENKTTGDRLSIIPEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIAGAGAYTYNEPGRTWYMSVNTHF
proteolysis
host cell cytoplasm; T=13 icosahedral viral capsid
metal ion binding serine-type peptidase activity structural molecule activity
Infectious pancreatic necrosis virus
3D-structure Capsid protein Host cytoplasm Hydrolase Metal-binding Protease Reference proteome Serine protease T=13 icosahedral capsid protein Virion
MSTSKATATY
MSTSKATATYLRSIMLPENGPASIPDDITERHILKQETSSYNLEVSESGSGLLVCFPGAPGSRVGAHYRWNLNQTALEFDQWLETSQDLKKAFNYGRLISRKYDIQSSTLPAGLYALNGTLNAATFEGSLSEVESLTYNSLMSLTTNPQDKVNNQLVTKGITVLNLPTGFDKPYVRLEDETPQGPQSMNGARMRCTAAIAPRRYEIDLPSERLPTVAATGTPTTIYEGNADIVNSTAVTGDITFQLEAEPVNETRFDFILQFLGLDNDVPVVTVTSSTLVTADNYRGASAKFTQSIPTEMITKPITRVKLAYQLNQQTAIANAATLGAKGPASVSFSSGNGNVPGVLRPITLVAYEKMTPQSILTVAGVSNYELIPNPDLLKNMVTKYGKYDPEGLNYAKMILSHREELDIRTVWRTEEYKERTRAFKEITDFTSDLPTSKAWGWRDLVRGIRKVAAPVLSTLFPMAAPLIGAADQFIGDLTKTNSAGGRYLSHAAGGRYHDVMDSWASGSEAGSYSKHLKTRLESNNYEEVELPKPTKGVIFPVVHTVESAPGEAFGSLVVVIPEAYPELLDPNQQVLSYFKNDTGCVWGIGEDIPFEGDDMCYTALPLKEIKRNGNIVVEKIFAGPAMGPSSQLALSLLVNDIDEGIPRMVFTGEIADDEETVIPICGVDIKAIAAHEHGLPLIGCQPGVDEMVANTSLASHLIQGGALPVQKAQGACRRIKYLGQLMRTTASGMDAELQGLLQATMARAKEVKDAEVFKLLKLMSWTRKNDLTDHMYEWSKEDPDAIKFGRLVSTPPKHQEKPKGPDQHTAQEAKATRISLDAVKAGADFASPEWIAENNYRGPSPGQFKYYMITGRVPNPGEEYEDYVRKPITRPTDMDKIRRLANSVYGLPHQEPAPDDFYQAVVEVFAENGGRGPDQDQMQDLRDLARQMKRRPRPAETRRQTKTPPRAATSSGSRFTPSGDDGEV
proteolysis host cell cytoplasm; T=13 icosahedral viral capsid metal ion binding serine-type peptidase activity structural molecule activity Infectious pancreatic necrosis virus 3D-structure Capsid protein Host cytoplasm Hydrolase Metal-binding Protease Reference proteome Serine protease T=13 icosahedral capsid protein Virion MSTSKATATY MSTSKATATYLRSIMLPENGPASIPDDITERHILKQETSSYNLEVSESGSGLLVCFPGAPGSRVGAHYRWNLNQTALEFDQWLETSQDLKKAFNYGRLISRKYDIQSSTLPAGLYALNGTLNAATFEGSLSEVESLTYNSLMSLTTNPQDKVNNQLVTKGITVLNLPTGFDKPYVRLEDETPQGPQSMNGARMRCTAAIAPRRYEIDLPSERLPTVAATGTPTTIYEGNADIVNSTAVTGDITFQLEAEPVNETRFDFILQFLGLDNDVPVVTVTSSTLVTADNYRGASAKFTQSIPTEMITKPITRVKLAYQLNQQTAIANAATLGAKGPASVSFSSGNGNVPGVLRPITLVAYEKMTPQSILTVAGVSNYELIPNPDLLKNMVTKYGKYDPEGLNYAKMILSHREELDIRTVWRTEEYKERTRAFKEITDFTSDLPTSKAWGWRDLVRGIRKVAAPVLSTLFPMAAPLIGAADQFIGDLTKTNSAGGRYLSHAAGGRYHDVMDSWASGSEAGSYSKHLKTRLESNNYEEVELPKPTKGVIFPVVHTVESAPGEAFGSLVVVIPEAYPELLDPNQQVLSYFKNDTGCVWGIGEDIPFEGDDMCYTALPLKEIKRNGNIVVEKIFAGPAMGPSSQLALSLLVNDIDEGIPRMVFTGEIADDEETVIPICGVDIKAIAAHEHGLPLIGCQPGVDEMVANTSLASHLIQGGALPVQKAQGACRRIKYLGQLMRTTASGMDAELQGLLQATMARAKEVKDAEVFKLLKLMSWTRKNDLTDHMYEWSKEDPDAIKFGRLVSTPPKHQEKPKGPDQHTAQEAKATRISLDAVKAGADFASPEWIAENNYRGPSPGQFKYYMITGRVPNPGEEYEDYVRKPITRPTDMDKIRRLANSVYGLPHQEPAPDDFYQAVVEVFAENGGRGPDQDQMQDLRDLARQMKRRPRPAETRRQTKTPPRAATSSGSRFTPSGDDGEV
maintenance of translational fidelity tRNA threonylcarbamoyladenosine modification
cytosol; EKC/KEOPS complex
glycosylation-dependent protein binding identical protein binding iron ion binding magnesium ion binding N(6)-L-threonylcarbamoyladenine synthase activity
Escherichia coli
3D-structure Acyltransferase Cytoplasm Iron Metal-binding Reference proteome Transferase tRNA processing
MRVLGIETSC
MRVLGIETSCDETGIAIYDDEKGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQAALKESGLTAKDIDAVAYTAGPGLVGALLVGATVGRSLAFAWDVPAIPVHHMEGHLLAPMLEDNPPEFPFVALLVSGGHTQLISVTGIGQYELLGESIDDAAGEAFDKTAKLLGLDYPGGPLLSKMAAQGTAGRFVFPRPMTDRPGLDFSFSGLKTFAANTIRDNGTDDQTRADIARAFEDAVVDTLMIKCKRALDQTGFKRLVMAGGVSANRTLRAKLAEMMKKRRGEVFYARPEFCTDNGAMIAYAGMVRFKAGATADLGVSVRPRWPLAELPAA
maintenance of translational fidelity tRNA threonylcarbamoyladenosine modification cytosol; EKC/KEOPS complex glycosylation-dependent protein binding identical protein binding iron ion binding magnesium ion binding N(6)-L-threonylcarbamoyladenine synthase activity Escherichia coli 3D-structure Acyltransferase Cytoplasm Iron Metal-binding Reference proteome Transferase tRNA processing MRVLGIETSC MRVLGIETSCDETGIAIYDDEKGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQAALKESGLTAKDIDAVAYTAGPGLVGALLVGATVGRSLAFAWDVPAIPVHHMEGHLLAPMLEDNPPEFPFVALLVSGGHTQLISVTGIGQYELLGESIDDAAGEAFDKTAKLLGLDYPGGPLLSKMAAQGTAGRFVFPRPMTDRPGLDFSFSGLKTFAANTIRDNGTDDQTRADIARAFEDAVVDTLMIKCKRALDQTGFKRLVMAGGVSANRTLRAKLAEMMKKRRGEVFYARPEFCTDNGAMIAYAGMVRFKAGATADLGVSVRPRWPLAELPAA
suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy
extracellular region; host cell Golgi membrane; host cell plasma membrane; membrane; virion component
GTP binding SH3 domain binding
Human immunodeficiency virus type 1 group M subtype B
AIDS Apoptosis Early protein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host autophagy by virus Inhibition of host MHC class I molecule presentation by virus Inhibition of host MHC class II molecule presentation by virus Lipoprotein Membrane Myristate Phosphoprotein Secreted SH3-binding Viral immunoevasion Virion Virulence
MGGKWSKSSV
MGGKWSKSSVVGWPAVRERMRRAEPAADGVGAASRDLEKHGAITSSNTAANNAACAWLEAQEEEKVGFPVTPQVPLRPMTYKAAVDLSHFLKEKGGLEGLIHSQRRQDILDLWIYHTQGYFPDWQNYTPGPGIRYPLTFGWRYKLVPVEPEKLEEANKGENTSLLHPVSLHGMDDPEREVLEWRFDSRLAFHHVARELHPEYFKNC
suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy extracellular region; host cell Golgi membrane; host cell plasma membrane; membrane; virion component GTP binding SH3 domain binding Human immunodeficiency virus type 1 group M subtype B AIDS Apoptosis Early protein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host autophagy by virus Inhibition of host MHC class I molecule presentation by virus Inhibition of host MHC class II molecule presentation by virus Lipoprotein Membrane Myristate Phosphoprotein Secreted SH3-binding Viral immunoevasion Virion Virulence MGGKWSKSSV MGGKWSKSSVVGWPAVRERMRRAEPAADGVGAASRDLEKHGAITSSNTAANNAACAWLEAQEEEKVGFPVTPQVPLRPMTYKAAVDLSHFLKEKGGLEGLIHSQRRQDILDLWIYHTQGYFPDWQNYTPGPGIRYPLTFGWRYKLVPVEPEKLEEANKGENTSLLHPVSLHGMDDPEREVLEWRFDSRLAFHHVARELHPEYFKNC
suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy
extracellular region; host cell Golgi membrane; host cell plasma membrane; membrane; virion component
GTP binding SH3 domain binding
Human immunodeficiency virus type 1 group M subtype B
AIDS Apoptosis Early protein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host autophagy by virus Inhibition of host MHC class I molecule presentation by virus Inhibition of host MHC class II molecule presentation by virus Lipoprotein Membrane Myristate Phosphoprotein Secreted SH3-binding Viral immunoevasion Virion Virulence
MGGKWSKSSV
MGGKWSKSSVVGWPAVRERMRRAEPAADGVGAVSRDLEKHGAITSSNTAATNADCAWLEAQEEEEVGFPVTPQVPLRPMTYKAAVDLSHFLKEKGGLEGLIHSQRRQDILDLWIHHTQGYFPDWQNYTPGPGVRYPLTFGWCYKLVPVEPEKEEANKGENTSLLHPVSLHGMDDPEREVLEWRFDSRLAFHHMARELHPEYFKNC
suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy extracellular region; host cell Golgi membrane; host cell plasma membrane; membrane; virion component GTP binding SH3 domain binding Human immunodeficiency virus type 1 group M subtype B AIDS Apoptosis Early protein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host autophagy by virus Inhibition of host MHC class I molecule presentation by virus Inhibition of host MHC class II molecule presentation by virus Lipoprotein Membrane Myristate Phosphoprotein Secreted SH3-binding Viral immunoevasion Virion Virulence MGGKWSKSSV MGGKWSKSSVVGWPAVRERMRRAEPAADGVGAVSRDLEKHGAITSSNTAATNADCAWLEAQEEEEVGFPVTPQVPLRPMTYKAAVDLSHFLKEKGGLEGLIHSQRRQDILDLWIHHTQGYFPDWQNYTPGPGVRYPLTFGWCYKLVPVEPEKEEANKGENTSLLHPVSLHGMDDPEREVLEWRFDSRLAFHHMARELHPEYFKNC
suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy
extracellular region; host cell Golgi membrane; host cell plasma membrane; membrane; virion component
GTP binding SH3 domain binding
Human immunodeficiency virus type 1 group M subtype B
AIDS Apoptosis Early protein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host autophagy by virus Inhibition of host MHC class I molecule presentation by virus Inhibition of host MHC class II molecule presentation by virus Lipoprotein Membrane Myristate Phosphoprotein Reference proteome Secreted SH3-binding Viral immunoevasion Virion Virulence
MGGKWSKRVT
MGGKWSKRVTGWPTVRERMRRAEPAELAADGVGAASRDLEKHGALTSSNTAATNADCAWLEAQEEEEVGFPVKPQVPLRPMTYKAALDLSHFLKEKGGLDGLIYSQKRQDILDLWVYHTQGYFPDWQNYTPGPGIRYPLTFGWCFKLVPVEPEKIEEANKGENNCLLHPMSQHGMDDPEREVLVWKSDSHLAFQHYARELHPEYYKNC
suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy extracellular region; host cell Golgi membrane; host cell plasma membrane; membrane; virion component GTP binding SH3 domain binding Human immunodeficiency virus type 1 group M subtype B AIDS Apoptosis Early protein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host autophagy by virus Inhibition of host MHC class I molecule presentation by virus Inhibition of host MHC class II molecule presentation by virus Lipoprotein Membrane Myristate Phosphoprotein Reference proteome Secreted SH3-binding Viral immunoevasion Virion Virulence MGGKWSKRVT MGGKWSKRVTGWPTVRERMRRAEPAELAADGVGAASRDLEKHGALTSSNTAATNADCAWLEAQEEEEVGFPVKPQVPLRPMTYKAALDLSHFLKEKGGLDGLIYSQKRQDILDLWVYHTQGYFPDWQNYTPGPGIRYPLTFGWCFKLVPVEPEKIEEANKGENNCLLHPMSQHGMDDPEREVLVWKSDSHLAFQHYARELHPEYYKNC
suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy
extracellular region; host cell Golgi membrane; host cell plasma membrane; membrane; virion component
GTP binding SH3 domain binding
Human immunodeficiency virus type 1 group M subtype B
AIDS Apoptosis Early protein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host autophagy by virus Inhibition of host MHC class I molecule presentation by virus Inhibition of host MHC class II molecule presentation by virus Lipoprotein Membrane Myristate Phosphoprotein Secreted SH3-binding Viral immunoevasion Virion Virulence
MGGKWSKRSV
MGGKWSKRSVVGWPTVRERMRKTEPAADGVGAASRDLEKHGAITSSNTPANNADCAWLEAQEEEEVGFPVRPQVPLRPMTYKAAVDLSHFLKEQGGLEGLIHSQRRQDILDLWIYHTQGYFPDWQNYTPGPGIRYPLCFGWCFKLVPVKPEKIEEANEGENNSLLHPMSLHGMEDPEREVLEWRFDNRLAFHHMARDLHPEYYKDCLTSMCLQGTFRWGISREARLGGTGEWRALRCCI
suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy extracellular region; host cell Golgi membrane; host cell plasma membrane; membrane; virion component GTP binding SH3 domain binding Human immunodeficiency virus type 1 group M subtype B AIDS Apoptosis Early protein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host autophagy by virus Inhibition of host MHC class I molecule presentation by virus Inhibition of host MHC class II molecule presentation by virus Lipoprotein Membrane Myristate Phosphoprotein Secreted SH3-binding Viral immunoevasion Virion Virulence MGGKWSKRSV MGGKWSKRSVVGWPTVRERMRKTEPAADGVGAASRDLEKHGAITSSNTPANNADCAWLEAQEEEEVGFPVRPQVPLRPMTYKAAVDLSHFLKEQGGLEGLIHSQRRQDILDLWIYHTQGYFPDWQNYTPGPGIRYPLCFGWCFKLVPVKPEKIEEANEGENNSLLHPMSLHGMEDPEREVLEWRFDNRLAFHHMARDLHPEYYKDCLTSMCLQGTFRWGISREARLGGTGEWRALRCCI
suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy
extracellular region; host cell Golgi membrane; host cell plasma membrane; membrane; virion component
GTP binding SH3 domain binding
Human immunodeficiency virus type 1 group M subtype B
AIDS Apoptosis Early protein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host autophagy by virus Inhibition of host MHC class I molecule presentation by virus Inhibition of host MHC class II molecule presentation by virus Lipoprotein Membrane Myristate Phosphoprotein Reference proteome Secreted SH3-binding Viral immunoevasion Virion Virulence
MGGKWSKSKM
MGGKWSKSKMGGWPAVRERMQKAEPAADGVGAASRDLEKHGTITSSNTAANNAACTWLEAQEDEDEEVGFPVRPQVPLRPMTFKAAVDLSHFLKEKGGLDGLVFSQKRQDILDLWVYHTQGYFPDWQNYTPGPGTRYPLTFGWCFKLVPVEPDKVEEATEGENNSLLHPICLHGMDDPEKEVLVWKFDSRLAFHHVAREKHPEYYKDC
suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy extracellular region; host cell Golgi membrane; host cell plasma membrane; membrane; virion component GTP binding SH3 domain binding Human immunodeficiency virus type 1 group M subtype B AIDS Apoptosis Early protein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host autophagy by virus Inhibition of host MHC class I molecule presentation by virus Inhibition of host MHC class II molecule presentation by virus Lipoprotein Membrane Myristate Phosphoprotein Reference proteome Secreted SH3-binding Viral immunoevasion Virion Virulence MGGKWSKSKM MGGKWSKSKMGGWPAVRERMQKAEPAADGVGAASRDLEKHGTITSSNTAANNAACTWLEAQEDEDEEVGFPVRPQVPLRPMTFKAAVDLSHFLKEKGGLDGLVFSQKRQDILDLWVYHTQGYFPDWQNYTPGPGTRYPLTFGWCFKLVPVEPDKVEEATEGENNSLLHPICLHGMDDPEKEVLVWKFDSRLAFHHVAREKHPEYYKDC
suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy
extracellular region; host cell Golgi membrane; host cell plasma membrane; membrane; virion component
GTP binding SH3 domain binding
Human immunodeficiency virus type 1 group M subtype A
AIDS Apoptosis Early protein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host autophagy by virus Inhibition of host MHC class I molecule presentation by virus Inhibition of host MHC class II molecule presentation by virus Lipoprotein Membrane Myristate Phosphoprotein Secreted SH3-binding Viral immunoevasion Virion Virulence
MGNKWSKGWP
MGNKWSKGWPAVRERIRQTPPAPPAAEGVGAASQDLAKHGAISSSNTATNNPDCAWLEAQEESEEVGFPVRPQVPLRPMTFKGAFDLSFFLKEKGGLDGLIYSKKRQEILDLWVYHTQGFFPDWHNYTPGPGTRYPLCFGWCFKLVPVDPREVEEANTGENNCLLHPMSQHGMDDDEREVLMWKFDSSLARKHLAREMHPEFYKD
suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy extracellular region; host cell Golgi membrane; host cell plasma membrane; membrane; virion component GTP binding SH3 domain binding Human immunodeficiency virus type 1 group M subtype A AIDS Apoptosis Early protein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host autophagy by virus Inhibition of host MHC class I molecule presentation by virus Inhibition of host MHC class II molecule presentation by virus Lipoprotein Membrane Myristate Phosphoprotein Secreted SH3-binding Viral immunoevasion Virion Virulence MGNKWSKGWP MGNKWSKGWPAVRERIRQTPPAPPAAEGVGAASQDLAKHGAISSSNTATNNPDCAWLEAQEESEEVGFPVRPQVPLRPMTFKGAFDLSFFLKEKGGLDGLIYSKKRQEILDLWVYHTQGFFPDWHNYTPGPGTRYPLCFGWCFKLVPVDPREVEEANTGENNCLLHPMSQHGMDDDEREVLMWKFDSSLARKHLAREMHPEFYKD
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral protein processing virion attachment to host cell virus-mediated perturbation of host defense response
host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane
identical protein binding structural molecule activity
Human immunodeficiency virus type 1 group M subtype B
3D-structure AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Palmitate Reference proteome Signal Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Viral immunoevasion Viral penetration into host cytoplasm Virion Virus endocytosis by host Virus entry into host cell
MRVKGIRRNY
MRVKGIRRNYQHWWGWGTMLLGLLMICSATEKLWVTVYYGVPVWKEATTTLFCASDAKAYDTEVHNVWATQACVPTDPNPQEVELVNVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVTLNCTDLRNTTNTNNSTANNNSNSEGTIKGGEMKNCSFNITTSIRDKMQKEYALLYKLDIVSIDNDSTSYRLISCNTSVITQACPKISFEPIPIHYCAPAGFAILKCNDKKFSGKGSCKNVSTVQCTHGIRPVVSTQLLLNGSLAEEEVVIRSENFTDNAKTIIVHLNESVQINCTRPNYNKRKRIHIGPGRAFYTTKNIIGTIRQAHCNISRAKWNDTLRQIVSKLKEQFKNKTIVFNQSSGGDPEIVMHSFNCGGEFFYCNTSPLFNSTWNGNNTWNNTTGSNNNITLQCKIKQIINMWQEVGKAMYAPPIEGQIRCSSNITGLLLTRDGGKDTDTNDTEIFRPGGGDMRDNWRSELYKYKVVTIEPLGVAPTKAKRRVVQREKRAAIGALFLGFLGAAGSTMGAASVTLTVQARLLLSGIVQQQNNLLRAIEAQQHMLQLTVWGIKQLQARVLAVERYLKDQQLLGFWGCSGKLICTTTVPWNASWSNKSLDDIWNNMTWMQWEREIDNYTSLIYSLLEKSQTQQEKNEQELLELDKWASLWNWFDITNWLWYIKIFIMIVGGLVGLRIVFAVLSIVNRVRQGYSPLSLQTRPPVPRGPDRPEGIEEEGGERDRDTSGRLVHGFLAIIWVDLRSLFLFSYHHRDLLLIAARIVELLGRRGWEVLKYWWNLLQYWSQELKSSAVSLLNATAIAVAEGTDRVIEVLQRAGRAILHIPTRIRQGLERALL
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral protein processing virion attachment to host cell virus-mediated perturbation of host defense response host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane identical protein binding structural molecule activity Human immunodeficiency virus type 1 group M subtype B 3D-structure AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Palmitate Reference proteome Signal Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Viral immunoevasion Viral penetration into host cytoplasm Virion Virus endocytosis by host Virus entry into host cell MRVKGIRRNY MRVKGIRRNYQHWWGWGTMLLGLLMICSATEKLWVTVYYGVPVWKEATTTLFCASDAKAYDTEVHNVWATQACVPTDPNPQEVELVNVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVTLNCTDLRNTTNTNNSTANNNSNSEGTIKGGEMKNCSFNITTSIRDKMQKEYALLYKLDIVSIDNDSTSYRLISCNTSVITQACPKISFEPIPIHYCAPAGFAILKCNDKKFSGKGSCKNVSTVQCTHGIRPVVSTQLLLNGSLAEEEVVIRSENFTDNAKTIIVHLNESVQINCTRPNYNKRKRIHIGPGRAFYTTKNIIGTIRQAHCNISRAKWNDTLRQIVSKLKEQFKNKTIVFNQSSGGDPEIVMHSFNCGGEFFYCNTSPLFNSTWNGNNTWNNTTGSNNNITLQCKIKQIINMWQEVGKAMYAPPIEGQIRCSSNITGLLLTRDGGKDTDTNDTEIFRPGGGDMRDNWRSELYKYKVVTIEPLGVAPTKAKRRVVQREKRAAIGALFLGFLGAAGSTMGAASVTLTVQARLLLSGIVQQQNNLLRAIEAQQHMLQLTVWGIKQLQARVLAVERYLKDQQLLGFWGCSGKLICTTTVPWNASWSNKSLDDIWNNMTWMQWEREIDNYTSLIYSLLEKSQTQQEKNEQELLELDKWASLWNWFDITNWLWYIKIFIMIVGGLVGLRIVFAVLSIVNRVRQGYSPLSLQTRPPVPRGPDRPEGIEEEGGERDRDTSGRLVHGFLAIIWVDLRSLFLFSYHHRDLLLIAARIVELLGRRGWEVLKYWWNLLQYWSQELKSSAVSLLNATAIAVAEGTDRVIEVLQRAGRAILHIPTRIRQGLERALL
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral protein processing virion attachment to host cell virus-mediated perturbation of host defense response
host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane
structural molecule activity
Human immunodeficiency virus type 1 group M subtype B
3D-structure AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Palmitate Signal Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Viral immunoevasion Viral penetration into host cytoplasm Virion Virus endocytosis by host Virus entry into host cell
MRVKGSGRNY
MRVKGSGRNYQHLWRWGTMLLGILMICSAAEQLWVTVYYGVPVWKEATTTLFCASDAKAYDTEVHNIWATHACVPTDPNPQEVVLGNVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVTLNCTNLRNDTSTNATNTTSSNRGKMEGGEMTNCSFNITTSIRSKVQKEYALFYKLDVVPIDNTSYTLINCNTSVITQACPKVSFEPIPIHYCARWFAILNCNNKKFNGTGPCTNVSTVQCTHGIRPVVSTHLLLNGSLAEEEVVLRSENFTDNAKTIIVQLKEAVEINCTRPNNNTTRSIHIGPGRAFYATGDIIGDIRQAHCNISRAKWNNTLKQIVIKLRDQFENKTIIFNRSSGGDPEIVMHSFNCGGEFFYCNSTQLFSSTWNGTEGSNNTGGNDTITLPCRIKEIINMWQEVGKAMYAPPIKGQVKCSSNITGLLLTRDGGNSKNGSKNENTEIFRPGGGDMRDNWRSELYKYKVVKIEPLGVAPTKAKRRVVQREKRAVGTIGAMFLGFLGAAGSTMGATSMTLTVQARLLLSGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARVLAVERYLRDQQLLGIWGCSGKLICTTTVPWNTSWSNKSLDKIWGNMTWMEWEREIDNYTSLIYTLIEESQNQQEKNEQELLELDKWASLWNWFNITNWLWYIKIFIMIVGGLVGLRIVFTVLSIVNRVRQGYSPLSFQTRLPSQRGPDRPEGIEEEGGERDRDRSGRLVDGFLAIIWVDXRSLCLFSYHRLRDLLLIVTRIVELLGRRGWEALKYWWNLLQYWSQELRNSAVSFVNATAIAVAEGTDRVIELLQRAFRAILHIPTRIRQGLERALQ
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral protein processing virion attachment to host cell virus-mediated perturbation of host defense response host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane structural molecule activity Human immunodeficiency virus type 1 group M subtype B 3D-structure AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Palmitate Signal Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Viral immunoevasion Viral penetration into host cytoplasm Virion Virus endocytosis by host Virus entry into host cell MRVKGSGRNY MRVKGSGRNYQHLWRWGTMLLGILMICSAAEQLWVTVYYGVPVWKEATTTLFCASDAKAYDTEVHNIWATHACVPTDPNPQEVVLGNVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVTLNCTNLRNDTSTNATNTTSSNRGKMEGGEMTNCSFNITTSIRSKVQKEYALFYKLDVVPIDNTSYTLINCNTSVITQACPKVSFEPIPIHYCARWFAILNCNNKKFNGTGPCTNVSTVQCTHGIRPVVSTHLLLNGSLAEEEVVLRSENFTDNAKTIIVQLKEAVEINCTRPNNNTTRSIHIGPGRAFYATGDIIGDIRQAHCNISRAKWNNTLKQIVIKLRDQFENKTIIFNRSSGGDPEIVMHSFNCGGEFFYCNSTQLFSSTWNGTEGSNNTGGNDTITLPCRIKEIINMWQEVGKAMYAPPIKGQVKCSSNITGLLLTRDGGNSKNGSKNENTEIFRPGGGDMRDNWRSELYKYKVVKIEPLGVAPTKAKRRVVQREKRAVGTIGAMFLGFLGAAGSTMGATSMTLTVQARLLLSGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARVLAVERYLRDQQLLGIWGCSGKLICTTTVPWNTSWSNKSLDKIWGNMTWMEWEREIDNYTSLIYTLIEESQNQQEKNEQELLELDKWASLWNWFNITNWLWYIKIFIMIVGGLVGLRIVFTVLSIVNRVRQGYSPLSFQTRLPSQRGPDRPEGIEEEGGERDRDRSGRLVDGFLAIIWVDXRSLCLFSYHRLRDLLLIVTRIVELLGRRGWEALKYWWNLLQYWSQELRNSAVSFVNATAIAVAEGTDRVIELLQRAFRAILHIPTRIRQGLERALQ
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral protein processing virion attachment to host cell virus-mediated perturbation of host defense response
host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane
structural molecule activity
Human immunodeficiency virus type 1 group M subtype B
AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Direct protein sequencing Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Palmitate Signal Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Viral immunoevasion Viral penetration into host cytoplasm Virion Virus endocytosis by host Virus entry into host cell
MAMRAKGIRK
MAMRAKGIRKNCQHLWRWGTMLLGMLMICSAAANLWVTVYYGVPVWKEATTTLFCASDAKAYDTEAHNVWATHACVPTNPNPQEVVLENVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVTLNCTDLNTNNTTNTTELSIIVVWEQRGKGEMRNCSFNITTSIRDKVQREYALFYKLDVEPIDDNKNTTNNTKYRLINCNTSVITQACPKVSFEPIPIHYCTPTGFALLKCNDKKFNGTGPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEVVIRSENFTNNAKTIIVQLNVSVEINCTRPNNHTRKRVTLGPGRVWYTTGEILGNIRQAHCNISRAQWNNTLQQIATTLREQFGNKTIAFNQSSGGDPEIVMHSFNCGGEFFYCNSTQLFNSAWNVTSNGTWSVTRKQKDTGDIITLPCRIKQIINRWQVVGKAMYALPIKGLIRCSSNITGLLLTRDGGGENQTTEIFRPGGGDMRDNWRSELYKYKVVKIEPLGVAPTKAKRRVVQREKRAVGMLGAMFLGFLGAAGSTMGATSMALTVQARQLLSGIVQQQNNLLRAIKAQQHLLQLTVWGIKQLQARILAVERYLKDQQLLGFWGCSGKLICTTAVPWNASWSNKTLDQIWNNMTWMEWDREIDNYTHLIYTLIEESQNQQEKNQQELLQLDKWASLWTWSDITKWLWYIKIFIMIVGGLIGLRIVFAVLSIVNRVRQGYSPLSFQTLLPNPRGPDRPEGTEEGGGERGRDGSTRLVHGFLALVWDDLRSLCLFSYHRLRDLLLIVARIVELLGRRGWEVLKYWWNLLQYWSQELKNSAVSLVNVTAIAVAEGTDRVIEVVQRIYRAFLHIPRRIRQGFERALL
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral protein processing virion attachment to host cell virus-mediated perturbation of host defense response host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane structural molecule activity Human immunodeficiency virus type 1 group M subtype B AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Direct protein sequencing Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Palmitate Signal Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Viral immunoevasion Viral penetration into host cytoplasm Virion Virus endocytosis by host Virus entry into host cell MAMRAKGIRK MAMRAKGIRKNCQHLWRWGTMLLGMLMICSAAANLWVTVYYGVPVWKEATTTLFCASDAKAYDTEAHNVWATHACVPTNPNPQEVVLENVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVTLNCTDLNTNNTTNTTELSIIVVWEQRGKGEMRNCSFNITTSIRDKVQREYALFYKLDVEPIDDNKNTTNNTKYRLINCNTSVITQACPKVSFEPIPIHYCTPTGFALLKCNDKKFNGTGPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEVVIRSENFTNNAKTIIVQLNVSVEINCTRPNNHTRKRVTLGPGRVWYTTGEILGNIRQAHCNISRAQWNNTLQQIATTLREQFGNKTIAFNQSSGGDPEIVMHSFNCGGEFFYCNSTQLFNSAWNVTSNGTWSVTRKQKDTGDIITLPCRIKQIINRWQVVGKAMYALPIKGLIRCSSNITGLLLTRDGGGENQTTEIFRPGGGDMRDNWRSELYKYKVVKIEPLGVAPTKAKRRVVQREKRAVGMLGAMFLGFLGAAGSTMGATSMALTVQARQLLSGIVQQQNNLLRAIKAQQHLLQLTVWGIKQLQARILAVERYLKDQQLLGFWGCSGKLICTTAVPWNASWSNKTLDQIWNNMTWMEWDREIDNYTHLIYTLIEESQNQQEKNQQELLQLDKWASLWTWSDITKWLWYIKIFIMIVGGLIGLRIVFAVLSIVNRVRQGYSPLSFQTLLPNPRGPDRPEGTEEGGGERGRDGSTRLVHGFLALVWDDLRSLCLFSYHRLRDLLLIVARIVELLGRRGWEVLKYWWNLLQYWSQELKNSAVSLVNVTAIAVAEGTDRVIEVVQRIYRAFLHIPRRIRQGFERALL
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral protein processing virion attachment to host cell virus-mediated perturbation of host defense response
host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane
structural molecule activity
Human immunodeficiency virus type 1 group M subtype B
3D-structure AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Palmitate Signal Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Viral immunoevasion Viral penetration into host cytoplasm Virion Virus endocytosis by host Virus entry into host cell
MRVKGIMRNC
MRVKGIMRNCQHLWIWGTMLFGMWMICSAVEQLWVTVYYGVPVWKEATTTLFCASDAKAYSTEAHNVWATHACVPTDPNPQEVILGNVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVTLNCIDKNITDWKNTTIIGGGEVKNCSFNITTSRRDKVHKEYALFYKLDVVPIKGDNNSSRYRLINCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNDKKFNGTGPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEIVIRSENFTDNAKTIIVHLNESVEINCTRPYNNVRRSLSIGPGRAFRTREIIGIIRQAHCNISRAKWNNTLKQIVEKLREQFKNKTIVFNHSSGGDPEIVTHSFNCGGEFFYCNSTQLFNSTWNGTDIKGDNKNSTLITLPCRIKQIINMWQGVGKAMYAPPIQGQIRCSSNITGLLLTRDGGNSSSREEIFRPGGGNMRDNWRSELYKYKVVRIEPLGVAPTKAKRRVVQREKRAVGTIGAMFLGFLGAAGSTMGAGSLTLTVQARQLLSGIVQQQNNLLRAIDAQQHLLQLTVWGIKQLQARVLAVERYLRDQQLLGIWGCSGKLICTTTVPWNASWSNKSMNQIWDNLTWMEWEREIDNYTSIIYSLIEESQNQQGKNEQELLELDKWASLWNWFDITNWLWYIKIFIMIVGGLIGLRIVFTVLSIVNRVRQGYSPLSFQTHLPTPRGPDRPEGIEEEGGERDRDRSVRLVHGFLALIWDDLRSLCLFSYHRLRDLLLIVKRIVELLGRRGWEALKYWWNLLQYWSKELKNSAVGLLNAIAIAVAEGTDRVIEVVQRICRAIIHIPRRIRQGLERALL
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral protein processing virion attachment to host cell virus-mediated perturbation of host defense response host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane structural molecule activity Human immunodeficiency virus type 1 group M subtype B 3D-structure AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Palmitate Signal Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Viral immunoevasion Viral penetration into host cytoplasm Virion Virus endocytosis by host Virus entry into host cell MRVKGIMRNC MRVKGIMRNCQHLWIWGTMLFGMWMICSAVEQLWVTVYYGVPVWKEATTTLFCASDAKAYSTEAHNVWATHACVPTDPNPQEVILGNVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVTLNCIDKNITDWKNTTIIGGGEVKNCSFNITTSRRDKVHKEYALFYKLDVVPIKGDNNSSRYRLINCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNDKKFNGTGPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEIVIRSENFTDNAKTIIVHLNESVEINCTRPYNNVRRSLSIGPGRAFRTREIIGIIRQAHCNISRAKWNNTLKQIVEKLREQFKNKTIVFNHSSGGDPEIVTHSFNCGGEFFYCNSTQLFNSTWNGTDIKGDNKNSTLITLPCRIKQIINMWQGVGKAMYAPPIQGQIRCSSNITGLLLTRDGGNSSSREEIFRPGGGNMRDNWRSELYKYKVVRIEPLGVAPTKAKRRVVQREKRAVGTIGAMFLGFLGAAGSTMGAGSLTLTVQARQLLSGIVQQQNNLLRAIDAQQHLLQLTVWGIKQLQARVLAVERYLRDQQLLGIWGCSGKLICTTTVPWNASWSNKSMNQIWDNLTWMEWEREIDNYTSIIYSLIEESQNQQGKNEQELLELDKWASLWNWFDITNWLWYIKIFIMIVGGLIGLRIVFTVLSIVNRVRQGYSPLSFQTHLPTPRGPDRPEGIEEEGGERDRDRSVRLVHGFLALIWDDLRSLCLFSYHRLRDLLLIVKRIVELLGRRGWEALKYWWNLLQYWSKELKNSAVGLLNAIAIAVAEGTDRVIEVVQRICRAIIHIPRRIRQGLERALL
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral protein processing virion attachment to host cell virus-mediated perturbation of host defense response
host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane
structural molecule activity
Human immunodeficiency virus type 1 group M subtype A
AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Palmitate Signal Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Viral immunoevasion Viral penetration into host cytoplasm Virion Virus endocytosis by host Virus entry into host cell
MKVKGIQGNW
MKVKGIQGNWQNWWKWGTLILGLVIICSAAENLWVTVYYGVPVWKDAETTLFCASDAKAYDTEKHNVWATHACVPTDPNPQELSLGNVTEKFDMWKNNMVEQMHEDVISLWDQSLKPCVKLTPLCVTLSCHNITIKDNNTNVDTEMKEEIKNCSYNMTTELRDKQRKIYSLFYRLDIVPIGGNSSNGDSSKYRLINCNTSAITQACPKVSFEPIPIHYCAPAGFAILKCRDEEFEGKGPCRNVSTVQCTHGIRPVVSTQLLLNGSLAEGEVRIRSENFTDNAKIIIVQLVKPVNITCMRPNNNTRKSISIGPGRAFFATGDIIGDIRQAHCNVSRTEWNDTLSKVAAQLRKHFVNTSTDIIFANSSGGDVEITTHSFNCGGEFFYCNTSGLFNGTWLNGTSNNTWKIDTVNDTIILPCRIKQIVNMWQRVGQAMYAPPIKGVIKCVSNITGILLTRDGVGNNTSNETFRPGGGDMRDNWRSELYKYKVVKIEPLGVAPTKAKRRVVAREKRAIGMGAFFLGFLGAAGSTMGAASITLTVQARRLLSGIVQQQNNLLRAIEAQQHLLKLTVWGIKQLQARILAVERYLKDQQLLGIWGCSGKIICPTNVPWNSSWSNKSQSDIWDKMTWLEWDKEVSNYTQVIYNLIEESQTQQEINERDLLALDKWANLWNWFDISNWLWYIKIFIMIVGGLIGLRIVFAVLSIINRVRQGYSPLSFQTLTHHQREPDRPERIEEGGGEQDRDRSIRLVSGFLPLAWDDLRSLCLFCYHRLRDCALIAARIVETLIRRGWETLKYLGNLVIYWGQELKNSAINLLDTVAIAVADWTDRVIEVVQRAGRAFLNIPRRIRQGLERALL
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral protein processing virion attachment to host cell virus-mediated perturbation of host defense response host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane structural molecule activity Human immunodeficiency virus type 1 group M subtype A AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Palmitate Signal Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Viral immunoevasion Viral penetration into host cytoplasm Virion Virus endocytosis by host Virus entry into host cell MKVKGIQGNW MKVKGIQGNWQNWWKWGTLILGLVIICSAAENLWVTVYYGVPVWKDAETTLFCASDAKAYDTEKHNVWATHACVPTDPNPQELSLGNVTEKFDMWKNNMVEQMHEDVISLWDQSLKPCVKLTPLCVTLSCHNITIKDNNTNVDTEMKEEIKNCSYNMTTELRDKQRKIYSLFYRLDIVPIGGNSSNGDSSKYRLINCNTSAITQACPKVSFEPIPIHYCAPAGFAILKCRDEEFEGKGPCRNVSTVQCTHGIRPVVSTQLLLNGSLAEGEVRIRSENFTDNAKIIIVQLVKPVNITCMRPNNNTRKSISIGPGRAFFATGDIIGDIRQAHCNVSRTEWNDTLSKVAAQLRKHFVNTSTDIIFANSSGGDVEITTHSFNCGGEFFYCNTSGLFNGTWLNGTSNNTWKIDTVNDTIILPCRIKQIVNMWQRVGQAMYAPPIKGVIKCVSNITGILLTRDGVGNNTSNETFRPGGGDMRDNWRSELYKYKVVKIEPLGVAPTKAKRRVVAREKRAIGMGAFFLGFLGAAGSTMGAASITLTVQARRLLSGIVQQQNNLLRAIEAQQHLLKLTVWGIKQLQARILAVERYLKDQQLLGIWGCSGKIICPTNVPWNSSWSNKSQSDIWDKMTWLEWDKEVSNYTQVIYNLIEESQTQQEINERDLLALDKWANLWNWFDISNWLWYIKIFIMIVGGLIGLRIVFAVLSIINRVRQGYSPLSFQTLTHHQREPDRPERIEEGGGEQDRDRSIRLVSGFLPLAWDDLRSLCLFCYHRLRDCALIAARIVETLIRRGWETLKYLGNLVIYWGQELKNSAINLLDTVAIAVADWTDRVIEVVQRAGRAFLNIPRRIRQGLERALL
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral protein processing virion attachment to host cell virus-mediated perturbation of host defense response
host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane
structural molecule activity
Human immunodeficiency virus type 1 group M subtype D
AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Palmitate Signal Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Viral immunoevasion Viral penetration into host cytoplasm Virion Virus endocytosis by host Virus entry into host cell
MRVMGIRMNY
MRVMGIRMNYQHLWKWGIMLLGILMTCSVAEDLWVTVYYGVPVWKEATTTLFCASDAKSYEPEAHNIWATHACVPTDPNPREIEMENVTENFNMWKNNMVEQMHEDIISLWDQNLKPCVKLTPLCVTLNCTNAGGNKTTNGNNTTNQEEQMMEKGEMKNCSFNITTVISDKKKQVHALFYRLDVVPIDDDNSANTSNTNYTNYRLINCNTSAITQACPKVTFEPIPIHYCAPAGFAILKCKDKKFNGTGPCKKVSTVQCTHGIRPVVSTQLLLNGSLAEEEIIIRSENLTNNVKTIIVHLNESVEINCTRPDNKITRQSTPIGLGQALYTTRIKGDIRQAYCNISAAAWNKTLQQVAKKLGDLLNQTTIIFKPPAGGDPEITTHSFNCGGEFFYCNTSRLFNSTWNSSTWNNDTLNSEGTIKLPCRIKQIINMWQGVGKAMYAPPIEGLIKCTSNITGLLLTRDGGVNNSTNETFRPGGGDMKDNWRNELYKYKVVRIEPLGIAPTRAKRRVVEREKRAIGLGAVFLGFLGAAGSTMGAVSVALTGQARQLLSGIVQQQNNLLRAIEAQQHMLQLTVWGIKQLQARVLAVESYLKDQQLLGIWGCSGKHICTTTVPWNSSWSNKSLEEIWNNMTWIEWEREIDNYTGVIYSLIENSQIQQEKNEQDLLQLDKWASLWNWFSITKWLWYIKIFIMIVGGLIGLRIVFTVLSLVNRVRQGYSPLSFQTLLPAPRGPDRPEGIEEEGGEQGRDRSIRLVNGFSALFWDDLRNLCLFSYHRLRDLILIATRIVELLGRRGWEAIKYLWSLLQYWTQELKNSFISLLNATAIAVAEGTDRIIELIRRAFRAVLHIPRRVRQGLERALL
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral protein processing virion attachment to host cell virus-mediated perturbation of host defense response host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane structural molecule activity Human immunodeficiency virus type 1 group M subtype D AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Palmitate Signal Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Viral immunoevasion Viral penetration into host cytoplasm Virion Virus endocytosis by host Virus entry into host cell MRVMGIRMNY MRVMGIRMNYQHLWKWGIMLLGILMTCSVAEDLWVTVYYGVPVWKEATTTLFCASDAKSYEPEAHNIWATHACVPTDPNPREIEMENVTENFNMWKNNMVEQMHEDIISLWDQNLKPCVKLTPLCVTLNCTNAGGNKTTNGNNTTNQEEQMMEKGEMKNCSFNITTVISDKKKQVHALFYRLDVVPIDDDNSANTSNTNYTNYRLINCNTSAITQACPKVTFEPIPIHYCAPAGFAILKCKDKKFNGTGPCKKVSTVQCTHGIRPVVSTQLLLNGSLAEEEIIIRSENLTNNVKTIIVHLNESVEINCTRPDNKITRQSTPIGLGQALYTTRIKGDIRQAYCNISAAAWNKTLQQVAKKLGDLLNQTTIIFKPPAGGDPEITTHSFNCGGEFFYCNTSRLFNSTWNSSTWNNDTLNSEGTIKLPCRIKQIINMWQGVGKAMYAPPIEGLIKCTSNITGLLLTRDGGVNNSTNETFRPGGGDMKDNWRNELYKYKVVRIEPLGIAPTRAKRRVVEREKRAIGLGAVFLGFLGAAGSTMGAVSVALTGQARQLLSGIVQQQNNLLRAIEAQQHMLQLTVWGIKQLQARVLAVESYLKDQQLLGIWGCSGKHICTTTVPWNSSWSNKSLEEIWNNMTWIEWEREIDNYTGVIYSLIENSQIQQEKNEQDLLQLDKWASLWNWFSITKWLWYIKIFIMIVGGLIGLRIVFTVLSLVNRVRQGYSPLSFQTLLPAPRGPDRPEGIEEEGGEQGRDRSIRLVNGFSALFWDDLRNLCLFSYHRLRDLILIATRIVELLGRRGWEAIKYLWSLLQYWTQELKNSFISLLNATAIAVAEGTDRIIELIRRAFRAVLHIPRRVRQGLERALL
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane suppression by virus of host tetherin activity suppression by virus of host type I interferon-mediated signaling pathway virion attachment to host cell
host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane
structural molecule activity
Human immunodeficiency virus type 2 subtype A
AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Inhibition of host tetherin by virus Lipoprotein Membrane Palmitate Signal Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Viral immunoevasion Viral penetration into host cytoplasm Virion Virus endocytosis by host Virus entry into host cell
MKGSKNQLLI
MKGSKNQLLIAIVLASAYLIHCKQFVTVFYGIPAWRNASIPLFCATKNRDTWGTIQCLPDNDDYQEITLNVTEAFDAWNNTVTEQAVEDVWNLFETSIKPCVKLTPLCVAMNCTRNMTTWTGRTDTQNITIINDTSHARADNCTGLKEEEMIDCQFSMTGLERDKRKQYTEAWYSKDVVCDNNTSSQSKCYMNHCNTSVITESCDKHYWDAMRFRYCAPPGFALLRCNDTNYSGFAPNCSKVVAATCTRMMETQTSTWFGFNGTRAENRTYIYWHGKDNRTIISLNNFYNLTMHCKRPGNKTVLPITFMSGFKFHSQPVINKKPRQAWCWFEGQWKEAMQEVKETLAKHPRYKGNRSRTENIKFKAPGRGSDPEVTYMWTNCRGESLYCNMTWFLNWVENRTGQKQRNYAPCRIRQIINTWHRVGKNLYLPPREGELTCNSTVTSIIANIDAGDQTNITFSAEAAELYRLELGDYKLVEITPIGFAPTSVKRYSSAHQRHTRGVFVLGFLGFLATAGSAMGAASLTLSAQSRTLLAGIVQQQQQLLDVVKRQQEMLRLTVWGTKNLQARVTAIEKYLKDQAQLNSWGCAFRQVCHTSVPWVNDTLTPDWNNMTWQEWEQKVRYLEANISQSLEQAQIQQEKNMYELQKLNSWDVFTNWLDFTSWVRYIQYGVYVVVGIVALRIVIYIVQMLSRLRKGYRPVFSSPPGYIQQIHIHKDQEQPAREETEEDVGSNGGDRSWPWPIAYIHFLIRLLIRLLTGLYNICRDLLSRISPILQPIFQSLQRALTAIRDWLRLKAAYLQYGCEWIQEAFQALARTTRETLAGAGRDLWRALQRIGRGILAVPRRIRQGAELALL
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane suppression by virus of host tetherin activity suppression by virus of host type I interferon-mediated signaling pathway virion attachment to host cell host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane structural molecule activity Human immunodeficiency virus type 2 subtype A AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Inhibition of host tetherin by virus Lipoprotein Membrane Palmitate Signal Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Viral immunoevasion Viral penetration into host cytoplasm Virion Virus endocytosis by host Virus entry into host cell MKGSKNQLLI MKGSKNQLLIAIVLASAYLIHCKQFVTVFYGIPAWRNASIPLFCATKNRDTWGTIQCLPDNDDYQEITLNVTEAFDAWNNTVTEQAVEDVWNLFETSIKPCVKLTPLCVAMNCTRNMTTWTGRTDTQNITIINDTSHARADNCTGLKEEEMIDCQFSMTGLERDKRKQYTEAWYSKDVVCDNNTSSQSKCYMNHCNTSVITESCDKHYWDAMRFRYCAPPGFALLRCNDTNYSGFAPNCSKVVAATCTRMMETQTSTWFGFNGTRAENRTYIYWHGKDNRTIISLNNFYNLTMHCKRPGNKTVLPITFMSGFKFHSQPVINKKPRQAWCWFEGQWKEAMQEVKETLAKHPRYKGNRSRTENIKFKAPGRGSDPEVTYMWTNCRGESLYCNMTWFLNWVENRTGQKQRNYAPCRIRQIINTWHRVGKNLYLPPREGELTCNSTVTSIIANIDAGDQTNITFSAEAAELYRLELGDYKLVEITPIGFAPTSVKRYSSAHQRHTRGVFVLGFLGFLATAGSAMGAASLTLSAQSRTLLAGIVQQQQQLLDVVKRQQEMLRLTVWGTKNLQARVTAIEKYLKDQAQLNSWGCAFRQVCHTSVPWVNDTLTPDWNNMTWQEWEQKVRYLEANISQSLEQAQIQQEKNMYELQKLNSWDVFTNWLDFTSWVRYIQYGVYVVVGIVALRIVIYIVQMLSRLRKGYRPVFSSPPGYIQQIHIHKDQEQPAREETEEDVGSNGGDRSWPWPIAYIHFLIRLLIRLLTGLYNICRDLLSRISPILQPIFQSLQRALTAIRDWLRLKAAYLQYGCEWIQEAFQALARTTRETLAGAGRDLWRALQRIGRGILAVPRRIRQGAELALL
membrane fusion involved in viral entry into host cell viral entry into host cell virion attachment to host cell
host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane
structural molecule activity
Simian immunodeficiency virus
3D-structure Apoptosis Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Palmitate Signal Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Viral penetration into host cytoplasm Virion Virus entry into host cell
MGCLGNQLLI
MGCLGNQLLIAILLLSVYGIYCTQYVTVFYGVPAWRNATIPLFCATKNRDTWGTTQCLPDNGDYSELALNVTESFDAWENTVTEQAIEDVWQLFETSIKPCVKLSPLCITMRCNKSETDRWGLTKSSTTITTAAPTSAPVSEKIDMVNETSSCIAQNNCTGLEQEQMISCKFTMTGLKRDKTKEYNETWYSTDLVCEQGNSTDNESRCYMNHCNTSVIQESCDKHYWDTIRFRYCAPPGYALLRCNDTNYSGFMPKCSKVVVSSCTRMMETQTSTWFGFNGTRAENRTYIYWHGRDNRTIISLNKYYNLTMKCRRPGNKTVLPVTIMSGLVFHSQPLTDRPKQAWCWFGGKWKDAIKEVKQTIVKHPRYTGTNNTDKINLTAPGGGDPEVTFMWTNCRGEFLYCKMNWFLNWVEDRDVTTQRPKERHRRNYVPCHIRQIINTWHKVGKNVYLPPREGDLTCNSTVTSLIANIDWTDGNQTSITMSAEVAELYRLELGDYKLVEITPIGLAPTDVKRYTTGGTSRNKRGVFVLGFLGFLATAGSAMGAASFRLTAQSRTLLAGIVQQQQQLLGVVKRQQELLRLTVWGTKNLQTRVTAIEKYLEDQAQLNAWGCAFRQVCHTTVPWPNASLTPDWNNDTWQEWERKVDFLEENITALLEEAQIQQEKNMYELQKLNSWDVFGNWFDLASWIKYIQYGIYVVVGVILLRIVIYIVQMLAKLRQGYRPVFSSPPSYFQXTHTQQDPALPTREGKEGDGGEGGGNSSWPWQIEYIHFLIRQLIRLLTWLFSNCRTLLSRAYQILQPILQRLSATLRRIREVLRTELTYLQYGWSYFHEAVQAGWRSATETLAGAWGDLWETLRRGGRWILAIPRRIRQGLELTLL
membrane fusion involved in viral entry into host cell viral entry into host cell virion attachment to host cell host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane structural molecule activity Simian immunodeficiency virus 3D-structure Apoptosis Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Palmitate Signal Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Viral penetration into host cytoplasm Virion Virus entry into host cell MGCLGNQLLI MGCLGNQLLIAILLLSVYGIYCTQYVTVFYGVPAWRNATIPLFCATKNRDTWGTTQCLPDNGDYSELALNVTESFDAWENTVTEQAIEDVWQLFETSIKPCVKLSPLCITMRCNKSETDRWGLTKSSTTITTAAPTSAPVSEKIDMVNETSSCIAQNNCTGLEQEQMISCKFTMTGLKRDKTKEYNETWYSTDLVCEQGNSTDNESRCYMNHCNTSVIQESCDKHYWDTIRFRYCAPPGYALLRCNDTNYSGFMPKCSKVVVSSCTRMMETQTSTWFGFNGTRAENRTYIYWHGRDNRTIISLNKYYNLTMKCRRPGNKTVLPVTIMSGLVFHSQPLTDRPKQAWCWFGGKWKDAIKEVKQTIVKHPRYTGTNNTDKINLTAPGGGDPEVTFMWTNCRGEFLYCKMNWFLNWVEDRDVTTQRPKERHRRNYVPCHIRQIINTWHKVGKNVYLPPREGDLTCNSTVTSLIANIDWTDGNQTSITMSAEVAELYRLELGDYKLVEITPIGLAPTDVKRYTTGGTSRNKRGVFVLGFLGFLATAGSAMGAASFRLTAQSRTLLAGIVQQQQQLLGVVKRQQELLRLTVWGTKNLQTRVTAIEKYLEDQAQLNAWGCAFRQVCHTTVPWPNASLTPDWNNDTWQEWERKVDFLEENITALLEEAQIQQEKNMYELQKLNSWDVFGNWFDLASWIKYIQYGIYVVVGVILLRIVIYIVQMLAKLRQGYRPVFSSPPSYFQXTHTQQDPALPTREGKEGDGGEGGGNSSWPWQIEYIHFLIRQLIRLLTWLFSNCRTLLSRAYQILQPILQRLSATLRRIREVLRTELTYLQYGWSYFHEAVQAGWRSATETLAGAWGDLWETLRRGGRWILAIPRRIRQGLELTLL
membrane fusion involved in viral entry into host cell viral entry into host cell virion attachment to host cell
host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane
structural molecule activity
Simian immunodeficiency virus
Apoptosis Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Palmitate Signal Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Viral penetration into host cytoplasm Virion Virus entry into host cell
MGCLGNQLLI
MGCLGNQLLIAILLLSVYGIYCIQYVTVFYGVPAWRNATIPLFCATKNRDTWGTTQCLPDNDDYSELALNVTESFDAWENTVTEQAIEDVWQLFETSIKPCVKLSPLCITMRCNKSETDKWGLTKSSTTTASTTTTTTAKSVETRDIVNETSPCVVHDNCTGLEQEPMISCKFNMTGLKRDKKKEYNETWYSADLVCEQGNSTGNESRCYMNHCNTSVIQECCDKDYWDAIRCRYCAPPGYALLRCNDTNYSGFMPNCSKVVVSSCTRMMETQTSTWFRFNGTRAENRTYIYWHGRDNRTIISLNKHYNLTMKCRRPGNKTVLPVTIMSALVFHSQPVNERPKQAWCRFGGNWKEAIKEVKQTIVKHPRYTGTNNTDKINLTAPRGGDPEVTFMWTNCRGEFLYCKMNWFLNWVEDRSLTTQKPKERHKRNYVPCHIRQIINTWHKVGKNVYLPPREGDLTCNSTVTSLIANINWTDGNQTSITMSAEVAELYRLELGDYKLVEITPIGLAPTNVKRYTTGGTSRNKRGVFVLGFLGFLATAGSAMGAASLTVTAQSRTLLAGIVQQQQQLLDVVKRQQELLRLTVWGTKNLQTRVSAIEKYLKDQAQLNAWGCAFRQVCHTTVPWPNASLTPDWNNETWQEWERKVDFLEANITALLEEAQIQQEKNMYELQKLNSWDVFGNWFDLTSWIKYIQYGIYIIVGVILLRIVIYIVQMLARLRQGYRPVFSSPPSYFQXTHTQQDPALPTKEGKKGDGGGSGGNSSWPWQIEYIHFLIRQLIRLLTWLFSNCRTLLSRAYQILQPIFQRLSATLRRIREVLRLELTYLQYGWSYFQEAVQAAQRSATETLAGAWGELWEALQRGGRWILAIPRRIRQGLELTLL
membrane fusion involved in viral entry into host cell viral entry into host cell virion attachment to host cell host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane structural molecule activity Simian immunodeficiency virus Apoptosis Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Palmitate Signal Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Viral penetration into host cytoplasm Virion Virus entry into host cell MGCLGNQLLI MGCLGNQLLIAILLLSVYGIYCIQYVTVFYGVPAWRNATIPLFCATKNRDTWGTTQCLPDNDDYSELALNVTESFDAWENTVTEQAIEDVWQLFETSIKPCVKLSPLCITMRCNKSETDKWGLTKSSTTTASTTTTTTAKSVETRDIVNETSPCVVHDNCTGLEQEPMISCKFNMTGLKRDKKKEYNETWYSADLVCEQGNSTGNESRCYMNHCNTSVIQECCDKDYWDAIRCRYCAPPGYALLRCNDTNYSGFMPNCSKVVVSSCTRMMETQTSTWFRFNGTRAENRTYIYWHGRDNRTIISLNKHYNLTMKCRRPGNKTVLPVTIMSALVFHSQPVNERPKQAWCRFGGNWKEAIKEVKQTIVKHPRYTGTNNTDKINLTAPRGGDPEVTFMWTNCRGEFLYCKMNWFLNWVEDRSLTTQKPKERHKRNYVPCHIRQIINTWHKVGKNVYLPPREGDLTCNSTVTSLIANINWTDGNQTSITMSAEVAELYRLELGDYKLVEITPIGLAPTNVKRYTTGGTSRNKRGVFVLGFLGFLATAGSAMGAASLTVTAQSRTLLAGIVQQQQQLLDVVKRQQELLRLTVWGTKNLQTRVSAIEKYLKDQAQLNAWGCAFRQVCHTTVPWPNASLTPDWNNETWQEWERKVDFLEANITALLEEAQIQQEKNMYELQKLNSWDVFGNWFDLTSWIKYIQYGIYIIVGVILLRIVIYIVQMLARLRQGYRPVFSSPPSYFQXTHTQQDPALPTKEGKKGDGGGSGGNSSWPWQIEYIHFLIRQLIRLLTWLFSNCRTLLSRAYQILQPIFQRLSATLRRIREVLRLELTYLQYGWSYFQEAVQAAQRSATETLAGAWGELWEALQRGGRWILAIPRRIRQGLELTLL
membrane fusion involved in viral entry into host cell viral entry into host cell virion attachment to host cell
host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane
structural molecule activity
Simian immunodeficiency virus agm.vervet
Apoptosis Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Membrane Signal Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Viral penetration into host cytoplasm Virion Virus entry into host cell
MRYTIITLGI
MRYTIITLGIIVIGIGIVLSKQWITVFYGIPVWKNSSVQAFCMTPTTSLWATTNCIPDDHDYTEVPLNITEPFEAWGDRNPLIAQAASNIHLLFEQTMKPCVKLSPLCIKMNCVELNSTRERATTPTTTPKSTGLPCVGPTSGENLQSCNASIIEREMEDEPASNCTFAMAGYVRDQKKNYYSVVWNDAEIYCKNKTNSTSKECYMIHCNDSVIKEACDKTYWDQLRLRYCAPAGYALLKCNDEDYNGYKQNCSNVSVVHCTGLMNTTVTTGLLLNGSYHENRTQIWQKHRVNNNTVLILFNKHYNLSVTCRRPGNKTVLPVTIMAGLVFHSQKYNMKLRQAWCHFEGNWRGAWREVKQKIVELPKDRYKGTNNTEHIYLQRQWGDPEASNLWFNCQGEFFYCKMDWFLNYLNNKTWDAYHNFCSSKKKGHAPGPCVQRTYVAYHIRSVINDSYTLSKKTYAPPREGHLQCRSTVTGMTVELNYNSKNRTNVTLSPQIESIWAAELGRYKLVEITPIGFAPTEVRRYTGGHERQKRVPFVLGFLGFLGAAGTAMGAAASSLTVQSRHLLAGILQQQKNLLAAVEAQQQMLKLTIWGVKNLNARVTALEKYLEDQARLNSWGCAWKQVCHTTVEWPWTNRTPDWQNMTWLEWERQIADLESNITGQLVKAREQEEKNLDAYQKLTSWSDFWSWFDFSKWLNILKMGFLVIVGIIGLRLLYTVYGCIVRVRQGYVPLSPQIHIHQVGKGRPDNADEPGEGGDNSRIKLESWXKDSKSRCMQLTAWLTRLNTWLYNSCLTLLIQLRKAFQYLQYGLAELKTGAQEILQTLAGVAQNACHQIWLACRSAYRNIVNSPRRVRQGLEEILN
membrane fusion involved in viral entry into host cell viral entry into host cell virion attachment to host cell host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane structural molecule activity Simian immunodeficiency virus agm.vervet Apoptosis Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Membrane Signal Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Viral penetration into host cytoplasm Virion Virus entry into host cell MRYTIITLGI MRYTIITLGIIVIGIGIVLSKQWITVFYGIPVWKNSSVQAFCMTPTTSLWATTNCIPDDHDYTEVPLNITEPFEAWGDRNPLIAQAASNIHLLFEQTMKPCVKLSPLCIKMNCVELNSTRERATTPTTTPKSTGLPCVGPTSGENLQSCNASIIEREMEDEPASNCTFAMAGYVRDQKKNYYSVVWNDAEIYCKNKTNSTSKECYMIHCNDSVIKEACDKTYWDQLRLRYCAPAGYALLKCNDEDYNGYKQNCSNVSVVHCTGLMNTTVTTGLLLNGSYHENRTQIWQKHRVNNNTVLILFNKHYNLSVTCRRPGNKTVLPVTIMAGLVFHSQKYNMKLRQAWCHFEGNWRGAWREVKQKIVELPKDRYKGTNNTEHIYLQRQWGDPEASNLWFNCQGEFFYCKMDWFLNYLNNKTWDAYHNFCSSKKKGHAPGPCVQRTYVAYHIRSVINDSYTLSKKTYAPPREGHLQCRSTVTGMTVELNYNSKNRTNVTLSPQIESIWAAELGRYKLVEITPIGFAPTEVRRYTGGHERQKRVPFVLGFLGFLGAAGTAMGAAASSLTVQSRHLLAGILQQQKNLLAAVEAQQQMLKLTIWGVKNLNARVTALEKYLEDQARLNSWGCAWKQVCHTTVEWPWTNRTPDWQNMTWLEWERQIADLESNITGQLVKAREQEEKNLDAYQKLTSWSDFWSWFDFSKWLNILKMGFLVIVGIIGLRLLYTVYGCIVRVRQGYVPLSPQIHIHQVGKGRPDNADEPGEGGDNSRIKLESWXKDSKSRCMQLTAWLTRLNTWLYNSCLTLLIQLRKAFQYLQYGLAELKTGAQEILQTLAGVAQNACHQIWLACRSAYRNIVNSPRRVRQGLEEILN
viral budding via host ESCRT complex
host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane
RNA binding structural molecule activity zinc ion binding
Human immunodeficiency virus type 1 group M subtype B
AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Methylation Myristate Phosphoprotein Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucleoprotein Viral release from host cell Virion Zinc Zinc-finger
MGARASVLSG
MGARASVLSGGELDRWEKIRLRPGGKKQYRLKHIVWASRKLERFAVNPGLLETSKGCRQILGQLQPSLQTGSEELRSLYNTVATLYCVHQRIEVRDTKEALDKIEEEQNKSKKKAQQAAADTGNSSQVSQNYPIVQNLQGQMVHQAISPRTLNAWVKVIEEKAFSPEVIPMFAALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTNNPPTPVGEIYKRWIILGLNKIVRMYSPISILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNWMTETLLVQNANPDCKTILKALGPAATLEEMMTACQGVGGPGHKARVLAEAMSQVTNSATIMMQRGNFRRQGKTVKCFNCGKEGHIARNCKAPRKKGCWKCGREGHQMKDCTERQANFLGKIWPSHKGRPGNFLQSRPEPTAPPEESFRFGDETTTPSQKQEPRDKELYPLASLRSLFGNDPSSQ
viral budding via host ESCRT complex host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane RNA binding structural molecule activity zinc ion binding Human immunodeficiency virus type 1 group M subtype B AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Methylation Myristate Phosphoprotein Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucleoprotein Viral release from host cell Virion Zinc Zinc-finger MGARASVLSG MGARASVLSGGELDRWEKIRLRPGGKKQYRLKHIVWASRKLERFAVNPGLLETSKGCRQILGQLQPSLQTGSEELRSLYNTVATLYCVHQRIEVRDTKEALDKIEEEQNKSKKKAQQAAADTGNSSQVSQNYPIVQNLQGQMVHQAISPRTLNAWVKVIEEKAFSPEVIPMFAALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTNNPPTPVGEIYKRWIILGLNKIVRMYSPISILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNWMTETLLVQNANPDCKTILKALGPAATLEEMMTACQGVGGPGHKARVLAEAMSQVTNSATIMMQRGNFRRQGKTVKCFNCGKEGHIARNCKAPRKKGCWKCGREGHQMKDCTERQANFLGKIWPSHKGRPGNFLQSRPEPTAPPEESFRFGDETTTPSQKQEPRDKELYPLASLRSLFGNDPSSQ
viral budding via host ESCRT complex
host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane
sequence-specific DNA binding structural molecule activity tRNA binding zinc ion binding
Human immunodeficiency virus type 1 group M subtype B
3D-structure AIDS Capsid protein Direct protein sequencing Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Methylation Myristate Phosphoprotein Reference proteome Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucleoprotein Viral release from host cell Virion Zinc Zinc-finger
MGARASVLSG
MGARASVLSGGELDRWEKIRLRPGGKKKYKLKHVVWASRELERFAINPGLLETSEGCRQILGQLQPSLQTGSEERKSLYNTVATLYCVHQKIKIKDTKEALEKIEEEQNKSKKKAQQAAADTGNRGNSSQVSQNYPIVQNIQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPAHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTNNPPIPVGEIYKRWIILGLNKIVRMYSPSSILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNWMTETLLVQNANPDCKTILKALGPAATLEEMMTACQGVGGPGHKARVLAEAMSQVTNSATIMMQRGNFRNQRKIIKCFNCGKEGHIAKNCRAPRKRGCWKCGKEGHQMKDCTERQANFLGKIWPSCKGRPGNFPQSRTEPTAPPEESFRFGEETTTPYQKQEKKQETIDKDLYPLASLKSLFGNDPLSQ
viral budding via host ESCRT complex host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane sequence-specific DNA binding structural molecule activity tRNA binding zinc ion binding Human immunodeficiency virus type 1 group M subtype B 3D-structure AIDS Capsid protein Direct protein sequencing Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Methylation Myristate Phosphoprotein Reference proteome Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucleoprotein Viral release from host cell Virion Zinc Zinc-finger MGARASVLSG MGARASVLSGGELDRWEKIRLRPGGKKKYKLKHVVWASRELERFAINPGLLETSEGCRQILGQLQPSLQTGSEERKSLYNTVATLYCVHQKIKIKDTKEALEKIEEEQNKSKKKAQQAAADTGNRGNSSQVSQNYPIVQNIQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPAHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTNNPPIPVGEIYKRWIILGLNKIVRMYSPSSILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNWMTETLLVQNANPDCKTILKALGPAATLEEMMTACQGVGGPGHKARVLAEAMSQVTNSATIMMQRGNFRNQRKIIKCFNCGKEGHIAKNCRAPRKRGCWKCGKEGHQMKDCTERQANFLGKIWPSCKGRPGNFPQSRTEPTAPPEESFRFGEETTTPYQKQEKKQETIDKDLYPLASLKSLFGNDPLSQ
viral process
host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane
RNA binding structural molecule activity
Human immunodeficiency virus type 1 group M subtype B
3D-structure AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Lipoprotein Membrane Methylation Myristate Phosphoprotein Ribosomal frameshifting RNA-binding Viral nucleoprotein Virion
MGARASVLSG
MGARASVLSGGELDKWEKIRLRPGGKKKYRLKHIVWASRELERFAVNPGLLETSEGCRQILGQLQPSLQTGSEELRSLYNTVATLYCVHQRIEKKDTKEALDKIEEEQNKCKKKAQQAAADTGNSSQVSQNYPIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTNNPPIPVGEIYKRWIILGLNKIVRMYSPTSILDIRQGPKEPFRDYVDRFYKTLRAEQATQEVKNWMTETLLVQNANPDCKTILKALGPAATLEEMMTACQGVGGPGHKARVLAEAMSQVTNPTTIMMQKGNFRNQRKT
viral process host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane RNA binding structural molecule activity Human immunodeficiency virus type 1 group M subtype B 3D-structure AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Lipoprotein Membrane Methylation Myristate Phosphoprotein Ribosomal frameshifting RNA-binding Viral nucleoprotein Virion MGARASVLSG MGARASVLSGGELDKWEKIRLRPGGKKKYRLKHIVWASRELERFAVNPGLLETSEGCRQILGQLQPSLQTGSEELRSLYNTVATLYCVHQRIEKKDTKEALDKIEEEQNKCKKKAQQAAADTGNSSQVSQNYPIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTNNPPIPVGEIYKRWIILGLNKIVRMYSPTSILDIRQGPKEPFRDYVDRFYKTLRAEQATQEVKNWMTETLLVQNANPDCKTILKALGPAATLEEMMTACQGVGGPGHKARVLAEAMSQVTNPTTIMMQKGNFRNQRKT
viral budding via host ESCRT complex
host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane
RNA binding structural molecule activity zinc ion binding
Human immunodeficiency virus type 1 group M subtype B
AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Methylation Myristate Phosphoprotein Reference proteome Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucleoprotein Viral release from host cell Virion Zinc Zinc-finger
MGARASVLSG
MGARASVLSGGKLDKWEKIRLRPRGKKRYKLKHIVWASRELERFAVNPSLLETAEGCRQILGQLQPALQTGSEELKSLYNAVATLYCVHQNIEVRDTKEALDKIEEEQNKSKKKAQQAAADTGNGSQVSQNYPIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTNNPPIPVGEIYKRWIILGLNKIVRMYSPISILDIRQGPKEPFRDYVDRFYKTLRAEQASQDVKNWMTETFLVQNANPDCKTILKALGPAATLEEMMTACQGVGGPSHKARILAEAMSQVTNSATIMLQKGNFRDQRKIVKCFNCGKVGHIAKNCRAPRKKGCWKCGKEGHQMKDCTNEGRQANFLGKIWPSHKGRPGNFLQSRPEPTAPPEESFRFGEETTPSQKQEKIDKELYPLASLKSLFGNDPSSQ
viral budding via host ESCRT complex host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane RNA binding structural molecule activity zinc ion binding Human immunodeficiency virus type 1 group M subtype B AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Methylation Myristate Phosphoprotein Reference proteome Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucleoprotein Viral release from host cell Virion Zinc Zinc-finger MGARASVLSG MGARASVLSGGKLDKWEKIRLRPRGKKRYKLKHIVWASRELERFAVNPSLLETAEGCRQILGQLQPALQTGSEELKSLYNAVATLYCVHQNIEVRDTKEALDKIEEEQNKSKKKAQQAAADTGNGSQVSQNYPIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTNNPPIPVGEIYKRWIILGLNKIVRMYSPISILDIRQGPKEPFRDYVDRFYKTLRAEQASQDVKNWMTETFLVQNANPDCKTILKALGPAATLEEMMTACQGVGGPSHKARILAEAMSQVTNSATIMLQKGNFRDQRKIVKCFNCGKVGHIAKNCRAPRKKGCWKCGKEGHQMKDCTNEGRQANFLGKIWPSHKGRPGNFLQSRPEPTAPPEESFRFGEETTPSQKQEKIDKELYPLASLKSLFGNDPSSQ
viral budding via host ESCRT complex
host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane
RNA binding structural molecule activity zinc ion binding
Human immunodeficiency virus type 2 subtype A
AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Phosphoprotein Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucleoprotein Viral release from host cell Virion Zinc Zinc-finger
MGARNSVLRG
MGARNSVLRGKKADELEKIRLRPGGKKKYKLKHIVWAANELDRFGLAESLLESKEGCQKILTVLDPLVPTGSENLKSLFNTVCVIWCIHAEEKVKDTEGAKQIVQRHLVAETGTAEKMPNTSRPTAPPSGKNFPVQQVAGNYTHIPLSPGTLNAWVKLVEEKKFGAEVVPGFQALSEGCTPYDINQMLNCVGDHQAAMQIIREIINEEAADWDVAHPIPGPLPAGQLREPRGSDIAGTTSTVEEQIQWMFRPQNPVPVGNIYRRWIQIGLQKCVRMYNPTNILDINQGPKEPFQSYVDRFYKSLRAEQTDPAVKNWMTQTLLIQNANPDCKLVLKGLGMNPTLEEMLTTCQGVGGPGQKARLMAEALKEVMAPAPIPFAAAQQRKTFKCWNCGKEGHSARQWSAPRRQGCWKCGKSGHVMANCPDRQAGFLGIGHWGKKARNFPAAQVPQGLTPTAPPLDPAVDLLEKYMQQGKRQREQRERPYKEVTEDLLRFEQAETPCRETTEDLLHLNSLFGKDQ
viral budding via host ESCRT complex host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane RNA binding structural molecule activity zinc ion binding Human immunodeficiency virus type 2 subtype A AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Phosphoprotein Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucleoprotein Viral release from host cell Virion Zinc Zinc-finger MGARNSVLRG MGARNSVLRGKKADELEKIRLRPGGKKKYKLKHIVWAANELDRFGLAESLLESKEGCQKILTVLDPLVPTGSENLKSLFNTVCVIWCIHAEEKVKDTEGAKQIVQRHLVAETGTAEKMPNTSRPTAPPSGKNFPVQQVAGNYTHIPLSPGTLNAWVKLVEEKKFGAEVVPGFQALSEGCTPYDINQMLNCVGDHQAAMQIIREIINEEAADWDVAHPIPGPLPAGQLREPRGSDIAGTTSTVEEQIQWMFRPQNPVPVGNIYRRWIQIGLQKCVRMYNPTNILDINQGPKEPFQSYVDRFYKSLRAEQTDPAVKNWMTQTLLIQNANPDCKLVLKGLGMNPTLEEMLTTCQGVGGPGQKARLMAEALKEVMAPAPIPFAAAQQRKTFKCWNCGKEGHSARQWSAPRRQGCWKCGKSGHVMANCPDRQAGFLGIGHWGKKARNFPAAQVPQGLTPTAPPLDPAVDLLEKYMQQGKRQREQRERPYKEVTEDLLRFEQAETPCRETTEDLLHLNSLFGKDQ
viral budding via host ESCRT complex
host cell cytoplasm; host cell nucleus; viral nucleocapsid
RNA binding structural molecule activity zinc ion binding
Simian immunodeficiency virus agm.vervet
Capsid protein Host cytoplasm Host nucleus Host-virus interaction Lipoprotein Metal-binding Myristate Phosphoprotein Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucleoprotein Viral release from host cell Virion Zinc Zinc-finger
MGAATSALNR
MGAATSALNRRQLDQFEKIRLRPNGKKKYQIKHLIWAGKEMERFGLHERLLETEEGCKRIIEVLYPLEPTGSEGLKSLFNLVCVLYCLHKEQKVKDTEEAVATVRQHCHLVEKEKSATETSSGQKKNDKGIAAPPGCSQNFPAQQQGNAWVHVPLSPRTLNAWVKAVEEKKFGAEIVPMFQALSEGCTPYDINQMLNVLGDHQGALQIVKEIINEEAAQWDVTHPLPAGPLPAGQLRDPRGSDIAGTTSSVQEQLEWIYTANPRVDVGAIYRRWIILGLQKCVKMYNPVSVLDIRQGPKEPFKDYVDRFYKAIRAEQASGEVKQWMTESLLIQNANPDCKVILKGLGMHPTLEEMLTACQGVGGPSYKAKVMAEMMQTMQNQNMVQQGGPKRQRPPLRCYNCGKFGHMQRQCPEPRKTKCLKCGKLGHLAKDCRGQVNFLGYGRWMGAKPRNFPAATLGAEPSAPPPPSGTTPYDPAKKLLQQYAEKGKQLREQKRNPPAMNPDWTEGYSLNSLFGEDQ
viral budding via host ESCRT complex host cell cytoplasm; host cell nucleus; viral nucleocapsid RNA binding structural molecule activity zinc ion binding Simian immunodeficiency virus agm.vervet Capsid protein Host cytoplasm Host nucleus Host-virus interaction Lipoprotein Metal-binding Myristate Phosphoprotein Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucleoprotein Viral release from host cell Virion Zinc Zinc-finger MGAATSALNR MGAATSALNRRQLDQFEKIRLRPNGKKKYQIKHLIWAGKEMERFGLHERLLETEEGCKRIIEVLYPLEPTGSEGLKSLFNLVCVLYCLHKEQKVKDTEEAVATVRQHCHLVEKEKSATETSSGQKKNDKGIAAPPGCSQNFPAQQQGNAWVHVPLSPRTLNAWVKAVEEKKFGAEIVPMFQALSEGCTPYDINQMLNVLGDHQGALQIVKEIINEEAAQWDVTHPLPAGPLPAGQLRDPRGSDIAGTTSSVQEQLEWIYTANPRVDVGAIYRRWIILGLQKCVKMYNPVSVLDIRQGPKEPFKDYVDRFYKAIRAEQASGEVKQWMTESLLIQNANPDCKVILKGLGMHPTLEEMLTACQGVGGPSYKAKVMAEMMQTMQNQNMVQQGGPKRQRPPLRCYNCGKFGHMQRQCPEPRKTKCLKCGKLGHLAKDCRGQVNFLGYGRWMGAKPRNFPAATLGAEPSAPPPPSGTTPYDPAKKLLQQYAEKGKQLREQKRNPPAMNPDWTEGYSLNSLFGEDQ
viral budding via host ESCRT complex
host cell cytoplasm; host cell nucleus; host cell plasma membrane; membrane; viral nucleocapsid
RNA binding structural molecule activity zinc ion binding
Simian immunodeficiency virus
3D-structure Capsid protein Host cell membrane Host cytoplasm Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Phosphoprotein Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucleoprotein Viral release from host cell Virion Zinc Zinc-finger
MGARNAVLSG
MGARNAVLSGKKADELEKIRLRPGGKKKYMLKHVVWAANELDRFGLAESLLENKEGCQKILSVLAPLVPTGSENLKSLYNTVCVIWCIHAEEKVKHTEEAKQIVQRHLVVETGTAETMPKTSRPTAPSSGRGGNYPVQQIGGNYVHLPLSPRTLNAWVKLIEEKKFGAEVVPGFQALSEGCTPYDINQMLNCVGDHQAAMQIIRDIINEEAADWDLQHPQPAPQQGQLREPSGSDIAGTTSSVDEQIQWMYRQQNPIPVGNIYRRWIQLRLQKCVRMYNPINILDVKQRPKEPFQSYVDRFYKSLRAEQTDAAVKNWMTQTLLIQNANPDCKLVLKGLGVNPTLEEMLTACQGVGGPGQKARLMAEALKEALRPVPTPFAAAQQRGPRKPIKCWNCGKEGHSARQCRAPRRQRCWKCGKMDHVMAKCPDRQAGFLGLGPWGKKPRNFPMAQVHQGLTPTAPPEDPAVDLLKNYMQLGKQQRESREKPYKEVTEDLLHLNSLFGGDQ
viral budding via host ESCRT complex host cell cytoplasm; host cell nucleus; host cell plasma membrane; membrane; viral nucleocapsid RNA binding structural molecule activity zinc ion binding Simian immunodeficiency virus 3D-structure Capsid protein Host cell membrane Host cytoplasm Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Phosphoprotein Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucleoprotein Viral release from host cell Virion Zinc Zinc-finger MGARNAVLSG MGARNAVLSGKKADELEKIRLRPGGKKKYMLKHVVWAANELDRFGLAESLLENKEGCQKILSVLAPLVPTGSENLKSLYNTVCVIWCIHAEEKVKHTEEAKQIVQRHLVVETGTAETMPKTSRPTAPSSGRGGNYPVQQIGGNYVHLPLSPRTLNAWVKLIEEKKFGAEVVPGFQALSEGCTPYDINQMLNCVGDHQAAMQIIRDIINEEAADWDLQHPQPAPQQGQLREPSGSDIAGTTSSVDEQIQWMYRQQNPIPVGNIYRRWIQLRLQKCVRMYNPINILDVKQRPKEPFQSYVDRFYKSLRAEQTDAAVKNWMTQTLLIQNANPDCKLVLKGLGVNPTLEEMLTACQGVGGPGQKARLMAEALKEALRPVPTPFAAAQQRGPRKPIKCWNCGKEGHSARQCRAPRRQRCWKCGKMDHVMAKCPDRQAGFLGLGPWGKKPRNFPMAQVHQGLTPTAPPEDPAVDLLKNYMQLGKQQRESREKPYKEVTEDLLHLNSLFGGDQ
viral budding via host ESCRT complex
host cell cytoplasm; host cell nucleus; host cell plasma membrane; membrane; viral nucleocapsid
RNA binding structural molecule activity zinc ion binding
Simian immunodeficiency virus
Capsid protein Host cell membrane Host cytoplasm Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Phosphoprotein Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucleoprotein Viral release from host cell Virion Zinc Zinc-finger
MGARNSVLSG
MGARNSVLSGKKADELEKIRLRPGGKKKYMLKHVVWAANELDRFGLAESLLENKEGCQKILSVLAPLVPTGSENLKSLYNTVCVIWCIHAEEKVKHTEEAKQIVQRHLVMETGTAETMPKTSRPTAPFSGRGGNYPVQQIGGNYTHLPLSPRTLNAWVKLIEEKKFGAEVVSGFQALSEGCLPYDINQMLNCVGDHQAAMQIIRDIINEEAADWDLQHPQQAPQQGQLREPSGSDIAGTTSTVEEQIQWMYRQQNPIPVGNIYRRWIQLGLQKCVRMYNPTNILDVKQGPKEPFQSYVDRFYKSLRAEQTDPAVKNWMTQTLLIQNANPDCKLVLKGLGTNPTLEEMLTACQGVGGPGQKARLMAEALKEALAPAPIPFAAAQQKGPRKPIKCWNCGKEGHSARQCRAPRRQGCWKCGKMDHVMAKCPNRQAGFLGLGPWGKKPRNFPMAQVHQGLTPTAPPEEPAVDLLKNYMHLGKQQRESRGKPYKEVTEDLLHLNSLFGGDQ
viral budding via host ESCRT complex host cell cytoplasm; host cell nucleus; host cell plasma membrane; membrane; viral nucleocapsid RNA binding structural molecule activity zinc ion binding Simian immunodeficiency virus Capsid protein Host cell membrane Host cytoplasm Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Phosphoprotein Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucleoprotein Viral release from host cell Virion Zinc Zinc-finger MGARNSVLSG MGARNSVLSGKKADELEKIRLRPGGKKKYMLKHVVWAANELDRFGLAESLLENKEGCQKILSVLAPLVPTGSENLKSLYNTVCVIWCIHAEEKVKHTEEAKQIVQRHLVMETGTAETMPKTSRPTAPFSGRGGNYPVQQIGGNYTHLPLSPRTLNAWVKLIEEKKFGAEVVSGFQALSEGCLPYDINQMLNCVGDHQAAMQIIRDIINEEAADWDLQHPQQAPQQGQLREPSGSDIAGTTSTVEEQIQWMYRQQNPIPVGNIYRRWIQLGLQKCVRMYNPTNILDVKQGPKEPFQSYVDRFYKSLRAEQTDPAVKNWMTQTLLIQNANPDCKLVLKGLGTNPTLEEMLTACQGVGGPGQKARLMAEALKEALAPAPIPFAAAQQKGPRKPIKCWNCGKEGHSARQCRAPRRQGCWKCGKMDHVMAKCPNRQAGFLGLGPWGKKPRNFPMAQVHQGLTPTAPPEEPAVDLLKNYMHLGKQQRESRGKPYKEVTEDLLHLNSLFGGDQ
DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by virus of host type I interferon-mediated signaling pathway
extracellular region; host cell cytoplasm; host cell nucleolus
actinin binding cyclin binding metal ion binding protein domain specific binding protein serine/threonine phosphatase inhibitor activity RNA-binding transcription regulator activity trans-activation response element binding
Human immunodeficiency virus type 1 group M subtype B
Acetylation Activator AIDS Alternative splicing Apoptosis Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Isopeptide bond Metal-binding Methylation Modulation of host chromatin by virus Modulation of host PP1 activity by virus Phosphoprotein Reference proteome RNA-binding Secreted Transcription Transcription regulation Ubl conjugation Viral immunoevasion Zinc
MEPVDPRLEP
MEPVDPRLEPWKHPGSQPKTACTTCYCKKCCFHCQVCFTKKALGISYGRKKRRQRRRAPEDSQTHQVSLPKQPAPQFRGDPTGPKESKKKVERETETHPVD
DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by virus of host type I interferon-mediated signaling pathway extracellular region; host cell cytoplasm; host cell nucleolus actinin binding cyclin binding metal ion binding protein domain specific binding protein serine/threonine phosphatase inhibitor activity RNA-binding transcription regulator activity trans-activation response element binding Human immunodeficiency virus type 1 group M subtype B Acetylation Activator AIDS Alternative splicing Apoptosis Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Isopeptide bond Metal-binding Methylation Modulation of host chromatin by virus Modulation of host PP1 activity by virus Phosphoprotein Reference proteome RNA-binding Secreted Transcription Transcription regulation Ubl conjugation Viral immunoevasion Zinc MEPVDPRLEP MEPVDPRLEPWKHPGSQPKTACTTCYCKKCCFHCQVCFTKKALGISYGRKKRRQRRRAPEDSQTHQVSLPKQPAPQFRGDPTGPKESKKKVERETETHPVD
DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by virus of host type I interferon-mediated signaling pathway
extracellular region; host cell cytoplasm; host cell nucleolus
actinin binding cyclin binding metal ion binding protein domain specific binding protein serine/threonine phosphatase inhibitor activity RNA-binding transcription regulator activity trans-activation response element binding
Human immunodeficiency virus type 1 group M subtype B
Acetylation Activator AIDS Alternative splicing Apoptosis Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Isopeptide bond Metal-binding Methylation Modulation of host chromatin by virus Modulation of host PP1 activity by virus Phosphoprotein RNA-binding Secreted Transcription Transcription regulation Ubl conjugation Viral immunoevasion Zinc
MDPVDPRLEP
MDPVDPRLEPWKHPGSQPKAACTSCYCKKCCFHCQVCFTTKGLGISYGRKKRRQRRRAPQDSQTHQVSLPKQPASQARGDPTGPKESKKKVERETETDPVD
DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by virus of host type I interferon-mediated signaling pathway extracellular region; host cell cytoplasm; host cell nucleolus actinin binding cyclin binding metal ion binding protein domain specific binding protein serine/threonine phosphatase inhibitor activity RNA-binding transcription regulator activity trans-activation response element binding Human immunodeficiency virus type 1 group M subtype B Acetylation Activator AIDS Alternative splicing Apoptosis Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Isopeptide bond Metal-binding Methylation Modulation of host chromatin by virus Modulation of host PP1 activity by virus Phosphoprotein RNA-binding Secreted Transcription Transcription regulation Ubl conjugation Viral immunoevasion Zinc MDPVDPRLEP MDPVDPRLEPWKHPGSQPKAACTSCYCKKCCFHCQVCFTTKGLGISYGRKKRRQRRRAPQDSQTHQVSLPKQPASQARGDPTGPKESKKKVERETETDPVD
DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by virus of host type I interferon-mediated signaling pathway
extracellular region; host cell cytoplasm; host cell nucleolus
actinin binding cyclin binding metal ion binding protein domain specific binding protein serine/threonine phosphatase inhibitor activity RNA-binding transcription regulator activity trans-activation response element binding
Human immunodeficiency virus type 1 group M subtype B
Acetylation Activator AIDS Alternative splicing Apoptosis Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Isopeptide bond Metal-binding Methylation Modulation of host chromatin by virus Modulation of host PP1 activity by virus Phosphoprotein RNA-binding Secreted Transcription Transcription regulation Ubl conjugation Viral immunoevasion Zinc
MEPVDPRLEP
MEPVDPRLEPWKHPGSQPKTACTNCYCKKCCFHCQVCFTKKALGISYGRKKRRQRRRAHQDSQNHQASLSKQPSSQTRGDPTGPKEPKKEVEREAETDPLD
DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by virus of host type I interferon-mediated signaling pathway extracellular region; host cell cytoplasm; host cell nucleolus actinin binding cyclin binding metal ion binding protein domain specific binding protein serine/threonine phosphatase inhibitor activity RNA-binding transcription regulator activity trans-activation response element binding Human immunodeficiency virus type 1 group M subtype B Acetylation Activator AIDS Alternative splicing Apoptosis Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Isopeptide bond Metal-binding Methylation Modulation of host chromatin by virus Modulation of host PP1 activity by virus Phosphoprotein RNA-binding Secreted Transcription Transcription regulation Ubl conjugation Viral immunoevasion Zinc MEPVDPRLEP MEPVDPRLEPWKHPGSQPKTACTNCYCKKCCFHCQVCFTKKALGISYGRKKRRQRRRAHQDSQNHQASLSKQPSSQTRGDPTGPKEPKKEVEREAETDPLD
DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by virus of host type I interferon-mediated signaling pathway
extracellular region; host cell cytoplasm; host cell nucleolus
actinin binding cyclin binding metal ion binding protein domain specific binding protein serine/threonine phosphatase inhibitor activity RNA-binding transcription regulator activity trans-activation response element binding
Human immunodeficiency virus type 1 group M subtype B
Acetylation Activator AIDS Alternative splicing Apoptosis Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Isopeptide bond Metal-binding Methylation Modulation of host chromatin by virus Modulation of host PP1 activity by virus Phosphoprotein Reference proteome RNA-binding Secreted Transcription Transcription regulation Ubl conjugation Viral immunoevasion Zinc
MEPVDPRLEP
MEPVDPRLEPWKHPGSQPKTACNNCYCKKCCYHCQVCFLTKGLGISYGRKKRRQRRGPPQGSQTHQVSLSKQPTSQPRGDPTGPKESKEKVERETETDPAVQ
DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by virus of host type I interferon-mediated signaling pathway extracellular region; host cell cytoplasm; host cell nucleolus actinin binding cyclin binding metal ion binding protein domain specific binding protein serine/threonine phosphatase inhibitor activity RNA-binding transcription regulator activity trans-activation response element binding Human immunodeficiency virus type 1 group M subtype B Acetylation Activator AIDS Alternative splicing Apoptosis Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Isopeptide bond Metal-binding Methylation Modulation of host chromatin by virus Modulation of host PP1 activity by virus Phosphoprotein Reference proteome RNA-binding Secreted Transcription Transcription regulation Ubl conjugation Viral immunoevasion Zinc MEPVDPRLEP MEPVDPRLEPWKHPGSQPKTACNNCYCKKCCYHCQVCFLTKGLGISYGRKKRRQRRGPPQGSQTHQVSLSKQPTSQPRGDPTGPKESKEKVERETETDPAVQ
receptor catabolic process suppression by virus of host tetherin activity suppression by virus of host type I interferon-mediated signaling pathway viral release from host cell
host cell membrane; membrane
CD4 receptor binding monoatomic cation channel activity
Human immunodeficiency virus type 1 group M subtype B
3D-structure AIDS Apoptosis Host membrane Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Inhibition of host tetherin by virus Ion channel Ion transport Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport Viral immunoevasion
MQPIPIVAIV
MQPIPIVAIVALVVAIIIAIVVWSIVIIEYRKILRQRKIDRLIDRLIERAEDSGNESEGEISALVEMGVEMGHHAPWDVDDL
receptor catabolic process suppression by virus of host tetherin activity suppression by virus of host type I interferon-mediated signaling pathway viral release from host cell host cell membrane; membrane CD4 receptor binding monoatomic cation channel activity Human immunodeficiency virus type 1 group M subtype B 3D-structure AIDS Apoptosis Host membrane Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Inhibition of host tetherin by virus Ion channel Ion transport Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport Viral immunoevasion MQPIPIVAIV MQPIPIVAIVALVVAIIIAIVVWSIVIIEYRKILRQRKIDRLIDRLIERAEDSGNESEGEISALVEMGVEMGHHAPWDVDDL
receptor catabolic process suppression by virus of host tetherin activity suppression by virus of host type I interferon-mediated signaling pathway viral release from host cell
host cell membrane; membrane
CD4 receptor binding monoatomic cation channel activity
Human immunodeficiency virus type 1 group M subtype B
AIDS Apoptosis Host membrane Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Inhibition of host tetherin by virus Ion channel Ion transport Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport Viral immunoevasion
MQPIQIAIAA
MQPIQIAIAALVVAIIIAIVVWSIVIIEYRKILRQRKIDRLIDRLIERAEDSGNESEGEISALVEMGVEMGHHAPWDIDDL
receptor catabolic process suppression by virus of host tetherin activity suppression by virus of host type I interferon-mediated signaling pathway viral release from host cell host cell membrane; membrane CD4 receptor binding monoatomic cation channel activity Human immunodeficiency virus type 1 group M subtype B AIDS Apoptosis Host membrane Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Inhibition of host tetherin by virus Ion channel Ion transport Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport Viral immunoevasion MQPIQIAIAA MQPIQIAIAALVVAIIIAIVVWSIVIIEYRKILRQRKIDRLIDRLIERAEDSGNESEGEISALVEMGVEMGHHAPWDIDDL
ascospore formation ascospore-type prospore-specific spindle pole body remodeling mitotic spindle assembly protein localization to meiotic spindle pole body spindle pole body organization
cell cortex of cell tip; cell division site; central plaque of mitotic spindle pole body; central plaque of spindle pole body; cytosol; division septum; growing cell tip; mating projection tip; meiotic spindle pole body; mitotic spindle pole body; myosin I complex; new growing cell tip; old growing cell tip
calcium ion binding enzyme regulator activity
Schizosaccharomyces pombe
Calcium Cytoplasm Cytoskeleton Metal-binding Reference proteome Repeat
MTTRNLTDEQ
MTTRNLTDEQIAEFREAFSLFDRDQDGNITSNELGVVMRSLGQSPTAAELQDMINEVDADGNGTIDFTEFLTMMARKMKDTDNEEEVREAFKVFDKDGNGYITVEELTHVLTSLGERLSQEEVADMIREADTDGDGVINYEEFSRVISSK
ascospore formation ascospore-type prospore-specific spindle pole body remodeling mitotic spindle assembly protein localization to meiotic spindle pole body spindle pole body organization cell cortex of cell tip; cell division site; central plaque of mitotic spindle pole body; central plaque of spindle pole body; cytosol; division septum; growing cell tip; mating projection tip; meiotic spindle pole body; mitotic spindle pole body; myosin I complex; new growing cell tip; old growing cell tip calcium ion binding enzyme regulator activity Schizosaccharomyces pombe Calcium Cytoplasm Cytoskeleton Metal-binding Reference proteome Repeat MTTRNLTDEQ MTTRNLTDEQIAEFREAFSLFDRDQDGNITSNELGVVMRSLGQSPTAAELQDMINEVDADGNGTIDFTEFLTMMARKMKDTDNEEEVREAFKVFDKDGNGYITVEELTHVLTSLGERLSQEEVADMIREADTDGDGVINYEEFSRVISSK
cellular response to organic substance cochlea development locomotory behavior long-term memory metanephric collecting duct development metanephric connecting tubule development metanephric distal convoluted tubule development metanephric part of ureteric bud development regulation of long-term synaptic potentiation regulation of presynaptic cytosolic calcium ion concentration retina layer formation short-term memory
axon; calyx of Held; cuticular plate; cytosol; dendrite; dendritic spine; extracellular exosome; GABA-ergic synapse; glutamatergic synapse; hippocampal mossy fiber to CA3 synapse; neuronal cell body; nucleus; postsynaptic cytosol; presynaptic cytosol; stereocilium; synapse; terminal bouton
calcium ion binding calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration vitamin D binding zinc ion binding
Homo sapiens
3D-structure Acetylation Alternative splicing Calcium Metal-binding Reference proteome Repeat Vitamin D
MAESHLQSSL
MAESHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDGGKLYRTDLALILCAGDN
cellular response to organic substance cochlea development locomotory behavior long-term memory metanephric collecting duct development metanephric connecting tubule development metanephric distal convoluted tubule development metanephric part of ureteric bud development regulation of long-term synaptic potentiation regulation of presynaptic cytosolic calcium ion concentration retina layer formation short-term memory axon; calyx of Held; cuticular plate; cytosol; dendrite; dendritic spine; extracellular exosome; GABA-ergic synapse; glutamatergic synapse; hippocampal mossy fiber to CA3 synapse; neuronal cell body; nucleus; postsynaptic cytosol; presynaptic cytosol; stereocilium; synapse; terminal bouton calcium ion binding calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration vitamin D binding zinc ion binding Homo sapiens 3D-structure Acetylation Alternative splicing Calcium Metal-binding Reference proteome Repeat Vitamin D MAESHLQSSL MAESHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDGGKLYRTDLALILCAGDN
positive regulation of canonical NF-kappaB signal transduction
cytosol; extracellular space; nucleoplasm; nucleus; perinuclear region of cytoplasm
actin binding calcium ion binding calcium-dependent protein binding chemoattractant activity identical protein binding protein-containing complex binding RAGE receptor binding transition metal ion binding
Rattus norvegicus
Acetylation Calcium Cytoplasm Metal-binding Nucleus Reference proteome Repeat Secreted
MARPLEEALD
MARPLEEALDVIVSTFHKYSGNEGDKFKLNKTELKELLTRELPSFLGRRTDEAAFQKLMNNLDSNRDNEVDFQEYCVFLSCIAMMCNEFFEGCPDKEPRKK
positive regulation of canonical NF-kappaB signal transduction cytosol; extracellular space; nucleoplasm; nucleus; perinuclear region of cytoplasm actin binding calcium ion binding calcium-dependent protein binding chemoattractant activity identical protein binding protein-containing complex binding RAGE receptor binding transition metal ion binding Rattus norvegicus Acetylation Calcium Cytoplasm Metal-binding Nucleus Reference proteome Repeat Secreted MARPLEEALD MARPLEEALDVIVSTFHKYSGNEGDKFKLNKTELKELLTRELPSFLGRRTDEAAFQKLMNNLDSNRDNEVDFQEYCVFLSCIAMMCNEFFEGCPDKEPRKK
membrane raft assembly mRNA transcription by RNA polymerase II positive regulation of focal adhesion assembly positive regulation of plasminogen activation positive regulation of stress fiber assembly positive regulation of substrate adhesion-dependent cell spreading positive regulation of transcription by RNA polymerase II protein localization to plasma membrane regulation of cell differentiation regulation of cell growth regulation of neurogenesis response to xenobiotic stimulus vesicle budding from membrane
AnxA2-p11 complex; cell surface; cytoplasm; extracellular space; plasma membrane; plasma membrane protein complex; RNA polymerase II transcription regulator complex
calcium ion binding calcium-dependent protein binding protein homodimerization activity transmembrane transporter binding
Rattus norvegicus
Acetylation Direct protein sequencing Reference proteome
MPSQMEHAME
MPSQMEHAMETMMLTFHRFAGEKNYLTKEDLRVLMEREFPGFLENQKDPLAVDKIMKDLDQCRDGKVGFQSFLSLVAGLIIACNDYFVVHMKQKK
membrane raft assembly mRNA transcription by RNA polymerase II positive regulation of focal adhesion assembly positive regulation of plasminogen activation positive regulation of stress fiber assembly positive regulation of substrate adhesion-dependent cell spreading positive regulation of transcription by RNA polymerase II protein localization to plasma membrane regulation of cell differentiation regulation of cell growth regulation of neurogenesis response to xenobiotic stimulus vesicle budding from membrane AnxA2-p11 complex; cell surface; cytoplasm; extracellular space; plasma membrane; plasma membrane protein complex; RNA polymerase II transcription regulator complex calcium ion binding calcium-dependent protein binding protein homodimerization activity transmembrane transporter binding Rattus norvegicus Acetylation Direct protein sequencing Reference proteome MPSQMEHAME MPSQMEHAMETMMLTFHRFAGEKNYLTKEDLRVLMEREFPGFLENQKDPLAVDKIMKDLDQCRDGKVGFQSFLSLVAGLIIACNDYFVVHMKQKK
proteolysis suppression by virus of host gene expression
host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane
aspartic-type endopeptidase activity lipid binding RNA binding structural molecule activity zinc ion binding
Human immunodeficiency virus type 1 group M subtype B
AIDS Aspartyl protease Capsid protein Eukaryotic host gene expression shutoff by virus Eukaryotic host translation shutoff by virus Host cell membrane Host cytoplasm Host endosome Host gene expression shutoff by virus Host membrane Host nucleus Host-virus interaction Hydrolase Lipid-binding Lipoprotein Membrane Metal-binding Myristate Phosphoprotein Protease Repeat Ribosomal frameshifting RNA-binding Viral nucleoprotein Viral release from host cell Virion Virion maturation Zinc Zinc-finger
MGARASVLSG
MGARASVLSGGELDRWEKIRLRPGGKKQYRLKHIVWASRKLERFAVNPGLLETSKGCRQILGQLQPSLQTGSEELRSLYNTVATLYCVHQRIEVRDTKEALDKIEEEQNKSKKKAQQAAADTGNSSQVSQNYPIVQNLQGQMVHQAISPRTLNAWVKVIEEKAFSPEVIPMFAALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTNNPPTPVGEIYKRWIILGLNKIVRMYSPISILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNWMTETLLVQNANPDCKTILKALGPAATLEEMMTACQGVGGPGHKARVLAEAMSQVTNSATIMMQRGNFRRQGKTVKCFNCGKEGHIARNCKAPRKKGCWKCGREGHQMKDCTERQANFLREDLAFPQGKAREFSSEQTRANSPTRGELQVWGRDNNSLSEAGAERQGTVSFSFPQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYDEV
proteolysis suppression by virus of host gene expression host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane aspartic-type endopeptidase activity lipid binding RNA binding structural molecule activity zinc ion binding Human immunodeficiency virus type 1 group M subtype B AIDS Aspartyl protease Capsid protein Eukaryotic host gene expression shutoff by virus Eukaryotic host translation shutoff by virus Host cell membrane Host cytoplasm Host endosome Host gene expression shutoff by virus Host membrane Host nucleus Host-virus interaction Hydrolase Lipid-binding Lipoprotein Membrane Metal-binding Myristate Phosphoprotein Protease Repeat Ribosomal frameshifting RNA-binding Viral nucleoprotein Viral release from host cell Virion Virion maturation Zinc Zinc-finger MGARASVLSG MGARASVLSGGELDRWEKIRLRPGGKKQYRLKHIVWASRKLERFAVNPGLLETSKGCRQILGQLQPSLQTGSEELRSLYNTVATLYCVHQRIEVRDTKEALDKIEEEQNKSKKKAQQAAADTGNSSQVSQNYPIVQNLQGQMVHQAISPRTLNAWVKVIEEKAFSPEVIPMFAALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTNNPPTPVGEIYKRWIILGLNKIVRMYSPISILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNWMTETLLVQNANPDCKTILKALGPAATLEEMMTACQGVGGPGHKARVLAEAMSQVTNSATIMMQRGNFRRQGKTVKCFNCGKEGHIARNCKAPRKKGCWKCGREGHQMKDCTERQANFLREDLAFPQGKAREFSSEQTRANSPTRGELQVWGRDNNSLSEAGAERQGTVSFSFPQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYDEV
muscle contraction muscle filament sliding
contractile fiber; cytosol; muscle myosin complex; myofibril; myosin II complex; sarcomere
calcium ion binding structural constituent of muscle
Homo sapiens
Acetylation Alternative splicing Disease variant Methylation Motor protein Muscle protein Myosin Phosphoprotein Reference proteome Repeat
MAPKKDVKKP
MAPKKDVKKPVAAAAAAPAPAPAPAPAPAPAKPKEEKIDLSAIKIEFSKEQQDEFKEAFLLFDRTGDSKITLSQVGDVLRALGTNPTNAEVRKVLGNPSNEELNAKKIEFEQFLPMMQAISNNKDQATYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQEDSNGCINYEAFVKHIMSI
muscle contraction muscle filament sliding contractile fiber; cytosol; muscle myosin complex; myofibril; myosin II complex; sarcomere calcium ion binding structural constituent of muscle Homo sapiens Acetylation Alternative splicing Disease variant Methylation Motor protein Muscle protein Myosin Phosphoprotein Reference proteome Repeat MAPKKDVKKP MAPKKDVKKPVAAAAAAPAPAPAPAPAPAPAKPKEEKIDLSAIKIEFSKEQQDEFKEAFLLFDRTGDSKITLSQVGDVLRALGTNPTNAEVRKVLGNPSNEELNAKKIEFEQFLPMMQAISNNKDQATYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQEDSNGCINYEAFVKHIMSI
cyclooxygenase pathway prostaglandin biosynthetic process regulation of blood pressure response to oxidative stress
cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle
dioxygenase activity heme binding metal ion binding peroxidase activity prostaglandin-endoperoxide synthase activity protein homodimerization activity
Ovis aries
3D-structure Dioxygenase Direct protein sequencing Disulfide bond EGF-like domain Endoplasmic reticulum Fatty acid biosynthesis Fatty acid metabolism Glycoprotein Heme Iron Lipid biosynthesis Lipid metabolism Membrane Metal-binding Microsome Oxidoreductase Peroxidase Prostaglandin biosynthesis Prostaglandin metabolism Reference proteome Signal Transmembrane Transmembrane helix
MSRQSISLRF
MSRQSISLRFPLLLLLLSPSPVFSADPGAPAPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPEIWTWLRTTLRPSPSFIHFLLTHGRWLWDFVNATFIRDTLMRLVLTVRSNLIPSPPTYNIAHDYISWESFSNVSYYTRILPSVPRDCPTPMDTKGKKQLPDAEFLSRRFLLRRKFIPDPQSTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQMLNGEVYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATIWLREHNRVCDLLKAEHPTWGDEQLFQTARLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGAQFQYRNRIAMEFNQLYHWHPLMPDSFRVGPQDYSYEQFLFNTSMLVDYGVEALVDAFSRQPAGRIGGGRNIDHHILHVAVDVIKESRVLRLQPFNEYRKRFGMKPYTSFQELTGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEMGAPFSLKGLLGNPICSPEYWKASTFGGEVGFNLVKTATLKKLVCLNTKTCPYVSFHVPDPRQEDRPGVERPPTEL
cyclooxygenase pathway prostaglandin biosynthetic process regulation of blood pressure response to oxidative stress cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle dioxygenase activity heme binding metal ion binding peroxidase activity prostaglandin-endoperoxide synthase activity protein homodimerization activity Ovis aries 3D-structure Dioxygenase Direct protein sequencing Disulfide bond EGF-like domain Endoplasmic reticulum Fatty acid biosynthesis Fatty acid metabolism Glycoprotein Heme Iron Lipid biosynthesis Lipid metabolism Membrane Metal-binding Microsome Oxidoreductase Peroxidase Prostaglandin biosynthesis Prostaglandin metabolism Reference proteome Signal Transmembrane Transmembrane helix MSRQSISLRF MSRQSISLRFPLLLLLLSPSPVFSADPGAPAPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPEIWTWLRTTLRPSPSFIHFLLTHGRWLWDFVNATFIRDTLMRLVLTVRSNLIPSPPTYNIAHDYISWESFSNVSYYTRILPSVPRDCPTPMDTKGKKQLPDAEFLSRRFLLRRKFIPDPQSTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQMLNGEVYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATIWLREHNRVCDLLKAEHPTWGDEQLFQTARLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGAQFQYRNRIAMEFNQLYHWHPLMPDSFRVGPQDYSYEQFLFNTSMLVDYGVEALVDAFSRQPAGRIGGGRNIDHHILHVAVDVIKESRVLRLQPFNEYRKRFGMKPYTSFQELTGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEMGAPFSLKGLLGNPICSPEYWKASTFGGEVGFNLVKTATLKKLVCLNTKTCPYVSFHVPDPRQEDRPGVERPPTEL
daunorubicin metabolic process doxorubicin metabolic process progesterone metabolic process prostaglandin biosynthetic process prostaglandin metabolic process
cytosol
alditol:NADP+ 1-oxidoreductase activity androsterone dehydrogenase activity bile acid binding ketosteroid monooxygenase activity prostaglandin D2 11-ketoreductase activity prostaglandin-F synthase activity
Bos taurus
Cytoplasm Direct protein sequencing Fatty acid biosynthesis Fatty acid metabolism Lipid biosynthesis Lipid metabolism NADP Oxidoreductase Prostaglandin biosynthesis Prostaglandin metabolism Reference proteome
MDPKSQRVKL
MDPKSQRVKLNDGHFIPVLGFGTYAPEEVPKSEALEATKFAIEVGFRHVDSAHLYQNEEQVGQAIRSKIADGTVKREDIFYTSKLWCNSLQPELVRPALEKSLQNLQLDYVDLYIIHSPVSLKPGNKFVPKDESGKLIFDSVDLCHTWEALEKCKDAGLTKSIGVSNFNHKQLEKILNKPGLKYKPVCNQVECHPYLNQSKLLEFCKSHDIVLVAYAALGAQLLSEWVNSNNPVLLEDPVLCAIAKKHKQTPALVALRYQVQRGVVVLAKSFNKKRIKENMQVFDFELTPEDMKAIDGLNRNIRYYDFQKGIGHPEYPFSEEY
daunorubicin metabolic process doxorubicin metabolic process progesterone metabolic process prostaglandin biosynthetic process prostaglandin metabolic process cytosol alditol:NADP+ 1-oxidoreductase activity androsterone dehydrogenase activity bile acid binding ketosteroid monooxygenase activity prostaglandin D2 11-ketoreductase activity prostaglandin-F synthase activity Bos taurus Cytoplasm Direct protein sequencing Fatty acid biosynthesis Fatty acid metabolism Lipid biosynthesis Lipid metabolism NADP Oxidoreductase Prostaglandin biosynthesis Prostaglandin metabolism Reference proteome MDPKSQRVKL MDPKSQRVKLNDGHFIPVLGFGTYAPEEVPKSEALEATKFAIEVGFRHVDSAHLYQNEEQVGQAIRSKIADGTVKREDIFYTSKLWCNSLQPELVRPALEKSLQNLQLDYVDLYIIHSPVSLKPGNKFVPKDESGKLIFDSVDLCHTWEALEKCKDAGLTKSIGVSNFNHKQLEKILNKPGLKYKPVCNQVECHPYLNQSKLLEFCKSHDIVLVAYAALGAQLLSEWVNSNNPVLLEDPVLCAIAKKHKQTPALVALRYQVQRGVVVLAKSFNKKRIKENMQVFDFELTPEDMKAIDGLNRNIRYYDFQKGIGHPEYPFSEEY
basement membrane disassembly cochlea morphogenesis detection of mechanical stimulus involved in sensory perception of sound negative regulation of apoptotic process negative regulation of epithelial cell proliferation negative regulation of epithelial to mesenchymal transition pilomotor reflex positive regulation by host of viral transcription positive regulation of cell growth positive regulation of gene expression positive regulation of hepatocyte proliferation positive regulation of plasminogen activation positive regulation of thyroid hormone generation potassium ion transmembrane transport proteolysis regulation of cell shape response to thyroid hormone
apical plasma membrane; cell surface; cell-cell junction; endoplasmic reticulum membrane; extracellular exosome; membrane; neuronal cell body; plasma membrane
peptidase activity serine-type endopeptidase activity serine-type exopeptidase activity serine-type peptidase activity
Homo sapiens
3D-structure Cell membrane Disulfide bond Glycoprotein Hydrolase Membrane Protease Reference proteome Serine protease Signal-anchor Transmembrane Transmembrane helix
MAQKEGGRTV
MAQKEGGRTVPCCSRPKVAALTAGTLLLLTAIGAASWAIVAVLLRSDQEPLYPVQVSSADARLMVFDKTEGTWRLLCSSRSNARVAGLSCEEMGFLRALTHSELDVRTAGANGTSGFFCVDEGRLPHTQRLLEVISVCDCPRGRFLAAICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWIFQAIKTHSEASGMVTQL
basement membrane disassembly cochlea morphogenesis detection of mechanical stimulus involved in sensory perception of sound negative regulation of apoptotic process negative regulation of epithelial cell proliferation negative regulation of epithelial to mesenchymal transition pilomotor reflex positive regulation by host of viral transcription positive regulation of cell growth positive regulation of gene expression positive regulation of hepatocyte proliferation positive regulation of plasminogen activation positive regulation of thyroid hormone generation potassium ion transmembrane transport proteolysis regulation of cell shape response to thyroid hormone apical plasma membrane; cell surface; cell-cell junction; endoplasmic reticulum membrane; extracellular exosome; membrane; neuronal cell body; plasma membrane peptidase activity serine-type endopeptidase activity serine-type exopeptidase activity serine-type peptidase activity Homo sapiens 3D-structure Cell membrane Disulfide bond Glycoprotein Hydrolase Membrane Protease Reference proteome Serine protease Signal-anchor Transmembrane Transmembrane helix MAQKEGGRTV MAQKEGGRTVPCCSRPKVAALTAGTLLLLTAIGAASWAIVAVLLRSDQEPLYPVQVSSADARLMVFDKTEGTWRLLCSSRSNARVAGLSCEEMGFLRALTHSELDVRTAGANGTSGFFCVDEGRLPHTQRLLEVISVCDCPRGRFLAAICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWIFQAIKTHSEASGMVTQL
mitochondrion organization negative regulation of cytoplasmic mRNA processing body assembly negative regulation of cytoplasmic translation phosphorylation protein kinase A signaling Ras protein signal transduction
cAMP-dependent protein kinase complex; cytoplasm; cytoplasmic stress granule; cytosol; nucleus; P-body
AMP-activated protein kinase activity ATP binding cAMP-dependent protein kinase activity protein kinase activity protein serine kinase activity
Saccharomyces cerevisiae
ATP-binding cAMP Kinase Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase
MYVDPMNNNE
MYVDPMNNNEIRKLSITAKTETTPDNVGQDIPVNAHSVHEECSSNTPVEINGRNSGKLKEEASAGICLVKKPMLQYRDTSGKYSLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPYEPPIQQGQGDTSQFDRYPEEEFNYGIQGEDPYMDLMKEF
mitochondrion organization negative regulation of cytoplasmic mRNA processing body assembly negative regulation of cytoplasmic translation phosphorylation protein kinase A signaling Ras protein signal transduction cAMP-dependent protein kinase complex; cytoplasm; cytoplasmic stress granule; cytosol; nucleus; P-body AMP-activated protein kinase activity ATP binding cAMP-dependent protein kinase activity protein kinase activity protein serine kinase activity Saccharomyces cerevisiae ATP-binding cAMP Kinase Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase MYVDPMNNNE MYVDPMNNNEIRKLSITAKTETTPDNVGQDIPVNAHSVHEECSSNTPVEINGRNSGKLKEEASAGICLVKKPMLQYRDTSGKYSLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPYEPPIQQGQGDTSQFDRYPEEEFNYGIQGEDPYMDLMKEF
c-di-GMP signaling culmination involved in sorocarp development positive regulation of gene expression regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway regulation of gene expression regulation of protein kinase A signaling regulation of protein phosphorylation regulation of sorocarp development regulation of sorocarp stalk cell differentiation response to curcumin sorocarp morphogenesis sporulation resulting in formation of a cellular spore
cAMP-dependent protein kinase complex; centrosome; cytosol
cAMP binding cAMP-dependent protein kinase inhibitor activity cAMP-dependent protein kinase regulator activity protein kinase A catalytic subunit binding
Dictyostelium discoideum
cAMP cAMP-binding Nucleotide-binding Phosphoprotein Reference proteome Repeat
MTNNISHNQK
MTNNISHNQKATEKVEAQNNNNITRKRRGAISSEPLGDKPATPLPNIPKTVETQQRLEQALSNNIMFSHLEEEERNVVFLAMVEVLYKAGDIIIKQGDEGDLFYVIDSGICDIYVCQNGGSPTLVMEVFEGGSFGELALIYGSPRAATVIARTDVRLWALNGATYRRILMDQTIKKRKLYEEFLEKVSILRHIDKYERVSLADALEPVNFQDGEVIVRQGDPGDRFYIIVEGKVVVTQETVPGDHSTSHVVSELHPSDYFGEIALLTDRPRAATVTSIGYTKCVELDRQRFNRLCGPIDQMLRRNMETYNQFLNRPPSSPNLTSQKS
c-di-GMP signaling culmination involved in sorocarp development positive regulation of gene expression regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway regulation of gene expression regulation of protein kinase A signaling regulation of protein phosphorylation regulation of sorocarp development regulation of sorocarp stalk cell differentiation response to curcumin sorocarp morphogenesis sporulation resulting in formation of a cellular spore cAMP-dependent protein kinase complex; centrosome; cytosol cAMP binding cAMP-dependent protein kinase inhibitor activity cAMP-dependent protein kinase regulator activity protein kinase A catalytic subunit binding Dictyostelium discoideum cAMP cAMP-binding Nucleotide-binding Phosphoprotein Reference proteome Repeat MTNNISHNQK MTNNISHNQKATEKVEAQNNNNITRKRRGAISSEPLGDKPATPLPNIPKTVETQQRLEQALSNNIMFSHLEEEERNVVFLAMVEVLYKAGDIIIKQGDEGDLFYVIDSGICDIYVCQNGGSPTLVMEVFEGGSFGELALIYGSPRAATVIARTDVRLWALNGATYRRILMDQTIKKRKLYEEFLEKVSILRHIDKYERVSLADALEPVNFQDGEVIVRQGDPGDRFYIIVEGKVVVTQETVPGDHSTSHVVSELHPSDYFGEIALLTDRPRAATVTSIGYTKCVELDRQRFNRLCGPIDQMLRRNMETYNQFLNRPPSSPNLTSQKS
isoleucine biosynthetic process valine biosynthetic process
cytosol
ketol-acid reductoisomerase activity magnesium ion binding
Salmonella typhimurium
Amino-acid biosynthesis Branched-chain amino acid biosynthesis Magnesium Metal-binding NADP Oxidoreductase Reference proteome Repeat
MANYFNTLNL
MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVVNLTPDKQHSDVVRSVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPQGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVAEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREETGKTAFETAPQYEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGSAIPEGAVDNAQLRDVNDAIRSHAIEQVGKKLRGYMTDMKRIAVAG
isoleucine biosynthetic process valine biosynthetic process cytosol ketol-acid reductoisomerase activity magnesium ion binding Salmonella typhimurium Amino-acid biosynthesis Branched-chain amino acid biosynthesis Magnesium Metal-binding NADP Oxidoreductase Reference proteome Repeat MANYFNTLNL MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVVNLTPDKQHSDVVRSVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPQGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVAEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREETGKTAFETAPQYEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGSAIPEGAVDNAQLRDVNDAIRSHAIEQVGKKLRGYMTDMKRIAVAG
adult locomotory behavior cellular response to light stimulus detection of UV detection of visible light G protein-coupled receptor signaling pathway negative regulation of compound eye retinal cell programmed cell death optomotor response phospholipase C-activating rhodopsin mediated signaling pathway photoreceptor cell morphogenesis phototaxis phototransduction response to light intensity rhabdomere development thermotaxis visual perception
cytoplasmic vesicle; early endosome; inaD signaling complex; rhabdomere; rhabdomere membrane; subrhabdomeral cisterna
G protein-coupled photoreceptor activity
Drosophila melanogaster
Cell membrane Cell projection Chromophore Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Photoreceptor protein Receptor Reference proteome Retinal protein Sensory transduction Transducer Transmembrane Transmembrane helix Vision
MESFAVAAAQ
MESFAVAAAQLGPHFAPLSNGSVVDKVTPDMAHLISPYWNQFPAMDPIWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITNTPMMGINLYFETWVLGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGRPMTIPLALGKIAYIWFMSSIWCLAPAFGWSRYVPEGNLTSCGIDYLERDWNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKKMNVKSLRSSEDAEKSAEGKLAKVALVTITLWFMAWTPYLVINCMGLFKFEGLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVFGKVDDGKSSDAQSQATASEAESKA
adult locomotory behavior cellular response to light stimulus detection of UV detection of visible light G protein-coupled receptor signaling pathway negative regulation of compound eye retinal cell programmed cell death optomotor response phospholipase C-activating rhodopsin mediated signaling pathway photoreceptor cell morphogenesis phototaxis phototransduction response to light intensity rhabdomere development thermotaxis visual perception cytoplasmic vesicle; early endosome; inaD signaling complex; rhabdomere; rhabdomere membrane; subrhabdomeral cisterna G protein-coupled photoreceptor activity Drosophila melanogaster Cell membrane Cell projection Chromophore Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Photoreceptor protein Receptor Reference proteome Retinal protein Sensory transduction Transducer Transmembrane Transmembrane helix Vision MESFAVAAAQ MESFAVAAAQLGPHFAPLSNGSVVDKVTPDMAHLISPYWNQFPAMDPIWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITNTPMMGINLYFETWVLGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGRPMTIPLALGKIAYIWFMSSIWCLAPAFGWSRYVPEGNLTSCGIDYLERDWNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKKMNVKSLRSSEDAEKSAEGKLAKVALVTITLWFMAWTPYLVINCMGLFKFEGLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVFGKVDDGKSSDAQSQATASEAESKA
photosynthetic electron transport in photosystem II
chloroplast thylakoid membrane; photosystem II
chlorophyll binding electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity metal ion binding
Spinacia oleracea
3D-structure Acetylation Chlorophyll Chloroplast Chromophore Direct protein sequencing Manganese Membrane Metal-binding Phosphoprotein Photosynthesis Photosystem II Plastid Reference proteome Thylakoid Transmembrane Transmembrane helix
MKTLYSLRRF
MKTLYSLRRFYPVETLFNGTLTLAGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEVIDTFPYFVSGVLHLISSAVLGFGGIYHALLGPETLEESFPFFGYVWKDRNKMTTILGIHLILLGIGAFLLVFKALYFGGVYDTWAPGGGDVRKITNVTLSPSIIFGCLLKSPFGGEGWIVSVDDLEDIIGGHVWIGVICILGGIWHILTKPFAWARRALVWSGEAYLSYSLAALSVFGFIACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYLMRSPTGEVIFGGETMRFWDLRAPWLEPLRGPNGLDLSRLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLSTSHFVLGFFLFVGHLWHAGRARAAAAGFEKGIDRDFEPVLSMTPLN
photosynthetic electron transport in photosystem II chloroplast thylakoid membrane; photosystem II chlorophyll binding electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity metal ion binding Spinacia oleracea 3D-structure Acetylation Chlorophyll Chloroplast Chromophore Direct protein sequencing Manganese Membrane Metal-binding Phosphoprotein Photosynthesis Photosystem II Plastid Reference proteome Thylakoid Transmembrane Transmembrane helix MKTLYSLRRF MKTLYSLRRFYPVETLFNGTLTLAGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEVIDTFPYFVSGVLHLISSAVLGFGGIYHALLGPETLEESFPFFGYVWKDRNKMTTILGIHLILLGIGAFLLVFKALYFGGVYDTWAPGGGDVRKITNVTLSPSIIFGCLLKSPFGGEGWIVSVDDLEDIIGGHVWIGVICILGGIWHILTKPFAWARRALVWSGEAYLSYSLAALSVFGFIACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYLMRSPTGEVIFGGETMRFWDLRAPWLEPLRGPNGLDLSRLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLSTSHFVLGFFLFVGHLWHAGRARAAAAGFEKGIDRDFEPVLSMTPLN
photosynthetic electron transport in photosystem II
chloroplast thylakoid membrane; photosystem II
chlorophyll binding electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity iron ion binding oxygen evolving activity
Pisum sativum
3D-structure Acetylation Chlorophyll Chloroplast Chromophore Electron transport Iron Magnesium Membrane Metal-binding Oxidoreductase Phosphoprotein Photosynthesis Photosystem II Plastid Thylakoid Transmembrane Transmembrane helix Transport
MTIALGKFTK
MTIALGKFTKDQNDLFDIMDDWLRRDRFVFVGWSGLLLFPCAYFAVGGWFTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSLAHSLLLLWGPEAQGDLTRWCQLGGLWTFVALHGAFGLIGFMLRQFELARSVQLRPYNAIAFSGPIAVFVSVFLIYPLGQSGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSALGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMATQDQPHENLIFPEEVLPRGNAL
photosynthetic electron transport in photosystem II chloroplast thylakoid membrane; photosystem II chlorophyll binding electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity iron ion binding oxygen evolving activity Pisum sativum 3D-structure Acetylation Chlorophyll Chloroplast Chromophore Electron transport Iron Magnesium Membrane Metal-binding Oxidoreductase Phosphoprotein Photosynthesis Photosystem II Plastid Thylakoid Transmembrane Transmembrane helix Transport MTIALGKFTK MTIALGKFTKDQNDLFDIMDDWLRRDRFVFVGWSGLLLFPCAYFAVGGWFTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSLAHSLLLLWGPEAQGDLTRWCQLGGLWTFVALHGAFGLIGFMLRQFELARSVQLRPYNAIAFSGPIAVFVSVFLIYPLGQSGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSALGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMATQDQPHENLIFPEEVLPRGNAL
photosynthesis, light reaction
plasma membrane light-harvesting complex; plasma membrane-derived chromatophore membrane
bacteriochlorophyll binding electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
Blastochloris viridis
3D-structure Bacteriochlorophyll Chlorophyll Chromophore Electron transport Formylation Membrane Photosynthesis Reaction center Transmembrane Transmembrane helix Transport
MYHGALAQHL
MYHGALAQHLDIAQLVWYAQWLVIWTVVLLYLRREDRREGYPLVEPLGLVKLAPEDGQVYELPYPKTFVLPHGGTVTVPRRRPETRELKLAQTDGFEGAPLQPTGNPLVDAVGPASYAERAEVVDATVDGKAKIVPLRVATDFSIAEGDVDPRGLPVVAADGVEAGTVTDLWVDRSEHYFRYLELSVAGSARTALIPLGFCDVKKDKIVVTSILSEQFANVPRLQSRDQITLREEDKVSAYYAGGLLYATPERAESLL
photosynthesis, light reaction plasma membrane light-harvesting complex; plasma membrane-derived chromatophore membrane bacteriochlorophyll binding electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity Blastochloris viridis 3D-structure Bacteriochlorophyll Chlorophyll Chromophore Electron transport Formylation Membrane Photosynthesis Reaction center Transmembrane Transmembrane helix Transport MYHGALAQHL MYHGALAQHLDIAQLVWYAQWLVIWTVVLLYLRREDRREGYPLVEPLGLVKLAPEDGQVYELPYPKTFVLPHGGTVTVPRRRPETRELKLAQTDGFEGAPLQPTGNPLVDAVGPASYAERAEVVDATVDGKAKIVPLRVATDFSIAEGDVDPRGLPVVAADGVEAGTVTDLWVDRSEHYFRYLELSVAGSARTALIPLGFCDVKKDKIVVTSILSEQFANVPRLQSRDQITLREEDKVSAYYAGGLLYATPERAESLL
latency-replication decision viral latency
host cell cytoplasm; transcription repressor complex
DNA binding
Escherichia phage Mu
3D-structure DNA-binding Early protein Host cytoplasm Host-virus interaction Latency-replication decision Reference proteome Repressor Transcription Transcription regulation Viral latency Viral latency initiation and maintenance
MKSNFIEKNN
MKSNFIEKNNTEKSIWCSPQEIMAADGMPGSVAGVHYRANVQGWTKQKKEGVKGGKAVEYDVMSMPTKEREQVIAHLGLSTPDTGAQANEKQDSSELINKLTTTLINMIEELEPDEARKALKLLSKGGLLALMPLVFNEQKLYSFIGFSQQSIQTLMMLDALPEEKRKEILSKYGIHEQESVVVPSQEPQEVKKAV
latency-replication decision viral latency host cell cytoplasm; transcription repressor complex DNA binding Escherichia phage Mu 3D-structure DNA-binding Early protein Host cytoplasm Host-virus interaction Latency-replication decision Reference proteome Repressor Transcription Transcription regulation Viral latency Viral latency initiation and maintenance MKSNFIEKNN MKSNFIEKNNTEKSIWCSPQEIMAADGMPGSVAGVHYRANVQGWTKQKKEGVKGGKAVEYDVMSMPTKEREQVIAHLGLSTPDTGAQANEKQDSSELINKLTTTLINMIEELEPDEARKALKLLSKGGLLALMPLVFNEQKLYSFIGFSQQSIQTLMMLDALPEEKRKEILSKYGIHEQESVVVPSQEPQEVKKAV
cell division osmosensory signaling MAPK cascade positive regulation of MAPK cascade protein folding protein stabilization regulation of cell cycle spindle pole body duplication
cytoplasm
heat shock protein binding protein kinase binding protein-folding chaperone binding unfolded protein binding
Saccharomyces cerevisiae
Cell cycle Cell division Chaperone Cytoplasm Phosphoprotein Reference proteome
MAIDYSKWDK
MAIDYSKWDKIELSDDSDVEVHPNVDKKSFIKWKQQSIHEQRFKRNQDIKNLETQVDMYSHLNKRVDRILSNLPESSLTDLPAVTKFLNANFDKMEKSKGENVDPEIATYNEMVEDLFEQLAKDLDKEGKDSKSPSLIRDAILKHRAKIDSVTVEAKKKLDELYKEKNAHISSEDIHTGFDSSFMNKQKGGAKPLEATPSEALSSAAESNILNKLAKSSVPQTFIDFKDDPMKLAKETEEFGKISINEYSKSQKFLLEHLPIISEQQKDALMMKAFEYQLHGDDKMTLQVIHQSELMAYIKEIYDMKKIPYLNPMELSNVINMFFEKVIFNKDKPMGKESFLRSVQEKFLHIQKRSKILQQEEMDESNAEGVETIQLKSLDDSTELEVNLPDFNSKDPEEMKKVKVFKTLIPEKMQEAIMTKNLDNINKVFEDIPIEEAEKLLEVFNDIDIIGIKAILENEKDFQSLKDQYEQDHEDATMENLSLNDRDGGGDNHEEVKHTADTVD
cell division osmosensory signaling MAPK cascade positive regulation of MAPK cascade protein folding protein stabilization regulation of cell cycle spindle pole body duplication cytoplasm heat shock protein binding protein kinase binding protein-folding chaperone binding unfolded protein binding Saccharomyces cerevisiae Cell cycle Cell division Chaperone Cytoplasm Phosphoprotein Reference proteome MAIDYSKWDK MAIDYSKWDKIELSDDSDVEVHPNVDKKSFIKWKQQSIHEQRFKRNQDIKNLETQVDMYSHLNKRVDRILSNLPESSLTDLPAVTKFLNANFDKMEKSKGENVDPEIATYNEMVEDLFEQLAKDLDKEGKDSKSPSLIRDAILKHRAKIDSVTVEAKKKLDELYKEKNAHISSEDIHTGFDSSFMNKQKGGAKPLEATPSEALSSAAESNILNKLAKSSVPQTFIDFKDDPMKLAKETEEFGKISINEYSKSQKFLLEHLPIISEQQKDALMMKAFEYQLHGDDKMTLQVIHQSELMAYIKEIYDMKKIPYLNPMELSNVINMFFEKVIFNKDKPMGKESFLRSVQEKFLHIQKRSKILQQEEMDESNAEGVETIQLKSLDDSTELEVNLPDFNSKDPEEMKKVKVFKTLIPEKMQEAIMTKNLDNINKVFEDIPIEEAEKLLEVFNDIDIIGIKAILENEKDFQSLKDQYEQDHEDATMENLSLNDRDGGGDNHEEVKHTADTVD
cytoplasmic translational initiation formation of cytoplasmic translation initiation complex translational initiation
cytoplasmic stress granule; eukaryotic 43S preinitiation complex; eukaryotic 48S preinitiation complex; eukaryotic translation initiation factor 3 complex; multi-eIF complex
identical protein binding RNA binding translation initiation factor activity translation initiation factor binding
Saccharomyces cerevisiae
3D-structure Cytoplasm Initiation factor Phosphoprotein Protein biosynthesis Reference proteome Repeat RNA-binding WD repeat
MKNFLPRTLK
MKNFLPRTLKNIYELYFNNISVHSIVSRNTQLKRSKIIQMTTETFEDIKLEDIPVDDIDFSDLEEQYKVTEEFNFDQYIVVNGAPVIPSAKVPVLKKALTSLFSKAGKVVNMEFPIDEATGKTKGFLFVECGSMNDAKKIIKSFHGKRLDLKHRLFLYTMKDVERYNSDDFDTEFREPDMPTFVPSSSLKSWLMDDKVRDQFVLQDDVKTSVFWNSMFNEEDSLVESRENWSTNYVRFSPKGTYLFSYHQQGVTAWGGPNFDRLRRFYHPDVRNSSVSPNEKYLVTFSTEPIIVEEDNEFSPFTKKNEGHQLCIWDIASGLLMATFPVIKSPYLKWPLVRWSYNDKYCARMVGDSLIVHDATKNFMPLEAKALKPSGIRDFSFAPEGVKLQPFRNGDEPSVLLAYWTPETNNSACTATIAEVPRGRVLKTVNLVQVSNVTLHWQNQAEFLCFNVERHTKSGKTQFSNLQICRLTERDIPVEKVELKDSVFEFGWEPHGNRFVTISVHEVADMNYAIPANTIRFYAPETKEKTDVIKRWSLVKEIPKTFANTVSWSPAGRFVVVGALVGPNMRRSDLQFYDMDYPGEKNINDNNDVSASLKDVAHPTYSAATNITWDPSGRYVTAWSSSLKHKVEHGYKIFNIAGNLVKEDIIAGFKNFAWRPRPASILSNAERKKVRKNLREWSAQFEEQDAMEADTAMRDLILHQRELLKQWTEYREKIGQEMEKSMNFKIFDVQPEDASDDFTTIEEIVEEVLEETKEKVE
cytoplasmic translational initiation formation of cytoplasmic translation initiation complex translational initiation cytoplasmic stress granule; eukaryotic 43S preinitiation complex; eukaryotic 48S preinitiation complex; eukaryotic translation initiation factor 3 complex; multi-eIF complex identical protein binding RNA binding translation initiation factor activity translation initiation factor binding Saccharomyces cerevisiae 3D-structure Cytoplasm Initiation factor Phosphoprotein Protein biosynthesis Reference proteome Repeat RNA-binding WD repeat MKNFLPRTLK MKNFLPRTLKNIYELYFNNISVHSIVSRNTQLKRSKIIQMTTETFEDIKLEDIPVDDIDFSDLEEQYKVTEEFNFDQYIVVNGAPVIPSAKVPVLKKALTSLFSKAGKVVNMEFPIDEATGKTKGFLFVECGSMNDAKKIIKSFHGKRLDLKHRLFLYTMKDVERYNSDDFDTEFREPDMPTFVPSSSLKSWLMDDKVRDQFVLQDDVKTSVFWNSMFNEEDSLVESRENWSTNYVRFSPKGTYLFSYHQQGVTAWGGPNFDRLRRFYHPDVRNSSVSPNEKYLVTFSTEPIIVEEDNEFSPFTKKNEGHQLCIWDIASGLLMATFPVIKSPYLKWPLVRWSYNDKYCARMVGDSLIVHDATKNFMPLEAKALKPSGIRDFSFAPEGVKLQPFRNGDEPSVLLAYWTPETNNSACTATIAEVPRGRVLKTVNLVQVSNVTLHWQNQAEFLCFNVERHTKSGKTQFSNLQICRLTERDIPVEKVELKDSVFEFGWEPHGNRFVTISVHEVADMNYAIPANTIRFYAPETKEKTDVIKRWSLVKEIPKTFANTVSWSPAGRFVVVGALVGPNMRRSDLQFYDMDYPGEKNINDNNDVSASLKDVAHPTYSAATNITWDPSGRYVTAWSSSLKHKVEHGYKIFNIAGNLVKEDIIAGFKNFAWRPRPASILSNAERKKVRKNLREWSAQFEEQDAMEADTAMRDLILHQRELLKQWTEYREKIGQEMEKSMNFKIFDVQPEDASDDFTTIEEIVEEVLEETKEKVE
cytoplasm protein quality control by the ubiquitin-proteasome system DNA duplex unwinding DNA repair DNA-templated transcription termination double-strand break repair via homologous recombination error-free postreplication DNA repair error-free translesion synthesis error-prone translesion synthesis meiotic DNA double-strand break formation mitotic G1 DNA damage checkpoint signaling proteasome-mediated ubiquitin-dependent protein catabolic process protein polyubiquitination protein ubiquitination regulation of dipeptide transport sporulation resulting in formation of a cellular spore stress-induced homeostatically regulated protein degradation pathway subtelomeric heterochromatin formation telomere maintenance via recombination transcription by RNA polymerase II ubiquitin-dependent ERAD pathway ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process via the N-end rule pathway
chromatin; chromosome, telomeric region; cytoplasm; HULC complex; MUB1-RAD6-UBR2 ubiquitin ligase complex; nucleus; Rad6-Rad18 complex; RAD6-UBR2 ubiquitin ligase complex; UBR1-RAD6 ubiquitin ligase complex
ATP binding proteasome binding ubiquitin conjugating enzyme activity ubiquitin-protein transferase activity
Saccharomyces cerevisiae
3D-structure ATP-binding Chromatin regulator Cytoplasm Direct protein sequencing DNA damage DNA repair Nucleotide-binding Nucleus Phosphoprotein Reference proteome Sporulation Transcription Transcription regulation Transferase Ubl conjugation pathway
MSTPARRRLM
MSTPARRRLMRDFKRMKEDAPPGVSASPLPDNVMVWNAMIIGPADTPYEDGTFRLLLEFDEEYPNKPPHVKFLSEMFHPNVYANGEICLDILQNRWTPTYDVASILTSIQSLFNDPNPASPANVEAATLFKDHKSQYVKRVKETVEKSWEDDMDDMDDDDDDDDDDDDDEAD
cytoplasm protein quality control by the ubiquitin-proteasome system DNA duplex unwinding DNA repair DNA-templated transcription termination double-strand break repair via homologous recombination error-free postreplication DNA repair error-free translesion synthesis error-prone translesion synthesis meiotic DNA double-strand break formation mitotic G1 DNA damage checkpoint signaling proteasome-mediated ubiquitin-dependent protein catabolic process protein polyubiquitination protein ubiquitination regulation of dipeptide transport sporulation resulting in formation of a cellular spore stress-induced homeostatically regulated protein degradation pathway subtelomeric heterochromatin formation telomere maintenance via recombination transcription by RNA polymerase II ubiquitin-dependent ERAD pathway ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process via the N-end rule pathway chromatin; chromosome, telomeric region; cytoplasm; HULC complex; MUB1-RAD6-UBR2 ubiquitin ligase complex; nucleus; Rad6-Rad18 complex; RAD6-UBR2 ubiquitin ligase complex; UBR1-RAD6 ubiquitin ligase complex ATP binding proteasome binding ubiquitin conjugating enzyme activity ubiquitin-protein transferase activity Saccharomyces cerevisiae 3D-structure ATP-binding Chromatin regulator Cytoplasm Direct protein sequencing DNA damage DNA repair Nucleotide-binding Nucleus Phosphoprotein Reference proteome Sporulation Transcription Transcription regulation Transferase Ubl conjugation pathway MSTPARRRLM MSTPARRRLMRDFKRMKEDAPPGVSASPLPDNVMVWNAMIIGPADTPYEDGTFRLLLEFDEEYPNKPPHVKFLSEMFHPNVYANGEICLDILQNRWTPTYDVASILTSIQSLFNDPNPASPANVEAATLFKDHKSQYVKRVKETVEKSWEDDMDDMDDDDDDDDDDDDDEAD
cysteine biosynthetic process L-homocysteine biosynthetic process methionine metabolic process sulfate assimilation transsulfuration
cytoplasm; plasma membrane
cysteine synthase activity O-acetylhomoserine aminocarboxypropyltransferase activity O-acetylhomoserine sulfhydrylase activity pyridoxal phosphate binding
Saccharomyces cerevisiae
3D-structure Amino-acid biosynthesis Cytoplasm Direct protein sequencing Isopeptide bond Methionine biosynthesis Phosphoprotein Pyridoxal phosphate Reference proteome Transferase Ubl conjugation
MPSHFDTVQL
MPSHFDTVQLHAGQENPGDNAHRSRAVPIYATTSYVFENSKHGSQLFGLEVPGYVYSRFQNPTSNVLEERIAALEGGAAALAVSSGQAAQTLAIQGLAHTGDNIVSTSYLYGGTYNQFKISFKRFGIEARFVEGDNPEEFEKVFDERTKAVYLETIGNPKYNVPDFEKIVAIAHKHGIPVVVDNTFGAGGYFCQPIKYGADIVTHSATKWIGGHGTTIGGIIVDSGKFPWKDYPEKFPQFSQPAEGYHGTIYNEAYGNLAYIVHVRTELLRDLGPLMNPFASFLLLQGVETLSLRAERHGENALKLAKWLEQSPYVSWVSYPGLASHSHHENAKKYLSNGFGGVLSFGVKDLPNADKETDPFKLSGAQVVDNLKLASNLANVGDAKTLVIAPYFTTHKQLNDKEKLASGVTKDLIRVSVGIEFIDDIIADFQQSFETVFAGQKP
cysteine biosynthetic process L-homocysteine biosynthetic process methionine metabolic process sulfate assimilation transsulfuration cytoplasm; plasma membrane cysteine synthase activity O-acetylhomoserine aminocarboxypropyltransferase activity O-acetylhomoserine sulfhydrylase activity pyridoxal phosphate binding Saccharomyces cerevisiae 3D-structure Amino-acid biosynthesis Cytoplasm Direct protein sequencing Isopeptide bond Methionine biosynthesis Phosphoprotein Pyridoxal phosphate Reference proteome Transferase Ubl conjugation MPSHFDTVQL MPSHFDTVQLHAGQENPGDNAHRSRAVPIYATTSYVFENSKHGSQLFGLEVPGYVYSRFQNPTSNVLEERIAALEGGAAALAVSSGQAAQTLAIQGLAHTGDNIVSTSYLYGGTYNQFKISFKRFGIEARFVEGDNPEEFEKVFDERTKAVYLETIGNPKYNVPDFEKIVAIAHKHGIPVVVDNTFGAGGYFCQPIKYGADIVTHSATKWIGGHGTTIGGIIVDSGKFPWKDYPEKFPQFSQPAEGYHGTIYNEAYGNLAYIVHVRTELLRDLGPLMNPFASFLLLQGVETLSLRAERHGENALKLAKWLEQSPYVSWVSYPGLASHSHHENAKKYLSNGFGGVLSFGVKDLPNADKETDPFKLSGAQVVDNLKLASNLANVGDAKTLVIAPYFTTHKQLNDKEKLASGVTKDLIRVSVGIEFIDDIIADFQQSFETVFAGQKP
hydrogen peroxide catabolic process response to hydrogen peroxide response to reactive oxygen species
cytoplasm; mitochondrion; peroxisome
catalase activity heme binding metal ion binding
Saccharomyces cerevisiae
Cytoplasm Direct protein sequencing Heme Hydrogen peroxide Iron Metal-binding Oxidoreductase Peroxidase Reference proteome
MNVFGKKEEK
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
hydrogen peroxide catabolic process response to hydrogen peroxide response to reactive oxygen species cytoplasm; mitochondrion; peroxisome catalase activity heme binding metal ion binding Saccharomyces cerevisiae Cytoplasm Direct protein sequencing Heme Hydrogen peroxide Iron Metal-binding Oxidoreductase Peroxidase Reference proteome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
adaptive immune response antigen processing and presentation, endogenous lipid antigen via MHC class Ib antigen processing and presentation, exogenous lipid antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity
endosome membrane; external side of plasma membrane; extracellular space; membrane raft; plasma membrane
endogenous lipid antigen binding exogenous lipid antigen binding lipopeptide binding
Homo sapiens
3D-structure Adaptive immunity Cell membrane Disulfide bond Endosome Glycoprotein Immunity Immunoglobulin domain Membrane Reference proteome Signal Transmembrane Transmembrane helix
MLFLLLPLLA
MLFLLLPLLAVLPGDGNADGLKEPLSFHVTWIASFYNHSWKQNLVSGWLSDLQTHTWDSNSSTIVFLCPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPFEIQVTGGCELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHENDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWEHHSSVGFIILAVIVPLLLLIGLALWFRKRCFC
adaptive immune response antigen processing and presentation, endogenous lipid antigen via MHC class Ib antigen processing and presentation, exogenous lipid antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity endosome membrane; external side of plasma membrane; extracellular space; membrane raft; plasma membrane endogenous lipid antigen binding exogenous lipid antigen binding lipopeptide binding Homo sapiens 3D-structure Adaptive immunity Cell membrane Disulfide bond Endosome Glycoprotein Immunity Immunoglobulin domain Membrane Reference proteome Signal Transmembrane Transmembrane helix MLFLLLPLLA MLFLLLPLLAVLPGDGNADGLKEPLSFHVTWIASFYNHSWKQNLVSGWLSDLQTHTWDSNSSTIVFLCPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPFEIQVTGGCELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHENDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWEHHSSVGFIILAVIVPLLLLIGLALWFRKRCFC