Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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cytoplasmic translational initiation positive regulation of formation of translation preinitiation complex regulation of translational initiation translational initiation | cytoplasm; cytoplasmic stress granule; eukaryotic translation initiation factor 4F complex; plasma membrane; ribosome | ATP binding ATP hydrolysis activity ATP-dependent activity, acting on RNA RNA binding RNA helicase activity translation initiation factor activity | Saccharomyces cerevisiae | 3D-structure Acetylation ATP-binding Cytoplasm Direct protein sequencing Helicase Hydrolase Initiation factor Nucleotide-binding Phosphoprotein Protein biosynthesis Reference proteome RNA-binding | MSEGITDIEE | MSEGITDIEESQIQTNYDKVVYKFDDMELDENLLRGVFGYGFEEPSAIQQRAIMPIIEGHDVLAQAQSGTGKTGTFSIAALQRIDTSVKAPQALMLAPTRELALQIQKVVMALAFHMDIKVHACIGGTSFVEDAEGLRDAQIVVGTPGRVFDNIQRRRFRTDKIKMFILDEADEMLSSGFKEQIYQIFTLLPPTTQVVLLSATMPNDVLEVTTKFMRNPVRILVKKDELTLEGIKQFYVNVEEEEYKYECLTDLYDSISVTQAVIFCNTRRKVEELTTKLRNDKFTVSAIYSDLPQQERDTIMKEFRSGSSRILISTDLL... | cytoplasmic translational initiation positive regulation of formation of translation preinitiation complex regulation of translational initiation translational initiation cytoplasm; cytoplasmic stress granule; eukaryotic translation initiation factor 4F complex; plasma membrane; ribosome ATP binding ATP hydrolysis acti... |
feeding behavior intestinal epithelial cell differentiation neuropeptide signaling pathway | extracellular region; extracellular space | G protein-coupled receptor binding hormone activity neuropeptide hormone activity neuropeptide Y receptor binding | Homo sapiens | 3D-structure Alternative splicing Amidation Cleavage on pair of basic residues Direct protein sequencing Hormone Phosphoprotein Reference proteome Secreted Signal | MVFVRRPWPA | MVFVRRPWPALTTVLLALLVCLGALVDAYPIKPEAPREDASPEELNRYYASLRHYLNLVTRQRYGKRDGPDTLLSKTFFPDGEDRPVRSRSEGPDLW | feeding behavior intestinal epithelial cell differentiation neuropeptide signaling pathway extracellular region; extracellular space G protein-coupled receptor binding hormone activity neuropeptide hormone activity neuropeptide Y receptor binding Homo sapiens 3D-structure Alternative splicing Amidation Cleavage on pair... |
central nervous system development chaeta morphogenesis epithelial cell proliferation involved in Malpighian tubule morphogenesis Malpighian tubule tip cell differentiation nervous system development neuroblast fate determination peripheral nervous system development positive regulation of antibacterial peptide biosynt... | nucleus; RNA polymerase II transcription regulator complex; transcription regulator complex | DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific protein heterodimerization activity RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific DNA binding | Drosophila melanogaster | Developmental protein Differentiation DNA-binding Neurogenesis Reference proteome | MALGSENHSV | MALGSENHSVFNDDEESSSAFNGPSVIRRNARERNRVKQVNNGFSQLRQHIPAAVIADLSNGRRGIGPGANKKLSKVSTLKMAVEYIRRLQKVLHENDQQKQKQLHLQQQHLHFQQQQQHQHLYAWHQELQLQSPTGSTSSCNSISSYCKPATSTIPGATPPNNFHTKLEASFEDYRNNSCSSGTEDEDILDYISLWQDDL | central nervous system development chaeta morphogenesis epithelial cell proliferation involved in Malpighian tubule morphogenesis Malpighian tubule tip cell differentiation nervous system development neuroblast fate determination peripheral nervous system development positive regulation of antibacterial peptide biosynt... |
central nervous system development chaeta development chaeta morphogenesis enteroendocrine cell differentiation Malpighian tubule tip cell differentiation negative regulation of apoptotic process nervous system development neuroblast fate determination peripheral nervous system development positive regulation of transc... | RNA polymerase II transcription regulator complex; transcription regulator complex | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor binding protein heterodimerization activity RNA polymerase II transcription regulatory region sequence... | Drosophila melanogaster | Developmental protein Differentiation Neurogenesis Reference proteome | MKNNNNTTKS | MKNNNNTTKSTTMSSSVLSTNETFPTTINSATKIFRYQHIMPAPSPLIPGGNQNQPAGTMPIKTRKYTPRGMALTRCSESVSSLSPGSSPAPYNVDQSQSVQRRNARERNRVKQVNNSFARLRQHIPQSIITDLTKGGGRGPHKKISKVDTLRIAVEYIRRLQDLVDDLNGGSNIGANNAVTQLQLCLDESSSHSSSSSTCSSSGHNTYYQNTISVSPLQQQQQLQRQQFNHQPLTALSLNTNLVGTSVPGGDAGCVSTSKNQQTCHSPTSSFNSSMSFDSGTYEGVPQQISTHLDRLDHLDNELHTHSQLQLKFEPYEH... | central nervous system development chaeta development chaeta morphogenesis enteroendocrine cell differentiation Malpighian tubule tip cell differentiation negative regulation of apoptotic process nervous system development neuroblast fate determination peripheral nervous system development positive regulation of transc... |
aminergic neurotransmitter loading into synaptic vesicle biogenic amine biosynthetic process cGMP transport compound eye pigmentation eye pigment metabolic process eye pigment precursor transport gravitaxis guanine transport histamine uptake male courtship behavior memory riboflavin transport transmembrane transport tr... | cytoplasmic vesicle; cytoplasmic vesicle membrane; pigment granule; pigment granule membrane; plasma membrane; presynapse | ABC-type 3',5'-cyclic GMP transmembrane transporter activity ABC-type guanine transporter activity amine transmembrane transporter activity ATP binding ATP hydrolysis activity ATPase-coupled transmembrane transporter activity guanine transmembrane transporter activity L-tryptophan transmembrane transporter activity pig... | Drosophila melanogaster | ATP-binding Cytoplasmic vesicle Glycoprotein Membrane Nucleotide-binding Pigment Reference proteome Translocase Transmembrane Transmembrane helix Transport | MGQEDQELLI | MGQEDQELLIRGGSKHPSAEHLNNGDSGAASQSCINQGFGQAKNYGTLLPPSPPEDSGSGSGQLAENLTYAWHNMDIFGAVNQPGSGWRQLVNRTRGLFCNERHIPAPRKHLLKNVCGVAYPGELLAVMGSSGAGKTTLLNALAFRSPQGIQVSPSGMRLLNGQPVDAKEMQARCAYVQQDDLFIGSLTAREHLIFQAMVRMPRHLTYRQRVARVDQVIQELSLSKCQHTIIGVPGRVKGLSGGERKRLAFASEALTDPPLLICDEPTSGLDSFTAHSVVQVLKKLSQKGKTVILTIHQPSSELFELFDKILLMAEGRVA... | aminergic neurotransmitter loading into synaptic vesicle biogenic amine biosynthetic process cGMP transport compound eye pigmentation eye pigment metabolic process eye pigment precursor transport gravitaxis guanine transport histamine uptake male courtship behavior memory riboflavin transport transmembrane transport tr... |
adenylate cyclase-activating G protein-coupled receptor signaling pathway intracellular calcium ion homeostasis regulation of cytosolic calcium ion concentration signal transduction | extracellular region; extracellular space | calcitonin receptor binding neuropeptide hormone activity | Homo sapiens | Amidation Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Hormone Reference proteome Secreted Signal | MGFRKFSPFL | MGFRKFSPFLALSILVLYQAGSLQAAPFRSALESSPDPATLSKEDARLLLAALVQDYVQMKASELKQEQETQGSSSAAQKRACNTATCVTHRLAGLLSRSGGMVKSNFVPTNVGSKAFGRRRRDLQA | adenylate cyclase-activating G protein-coupled receptor signaling pathway intracellular calcium ion homeostasis regulation of cytosolic calcium ion concentration signal transduction extracellular region; extracellular space calcitonin receptor binding neuropeptide hormone activity Homo sapiens Amidation Cleavage on pai... |
glucose metabolic process glycolytic process innate immune response microtubule cytoskeleton organization neuron apoptotic process peptidyl-cysteine S-trans-nitrosylation positive regulation of canonical NF-kappaB signal transduction positive regulation of type I interferon production protein stabilization regulation o... | cytoplasm; cytosol; extrinsic component of synaptic vesicle membrane; GAIT complex; microtubule cytoskeleton; nucleus | disordered domain specific binding glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity microtubule binding NAD binding NADP binding peptidyl-cysteine S-nitrosylase activity | Bos taurus | 3D-structure Acetylation ADP-ribosylation Apoptosis Cytoplasm Cytoskeleton Direct protein sequencing Glycolysis Immunity Innate immunity Isopeptide bond Methylation NAD Nucleus Oxidoreductase Phosphoprotein Reference proteome S-nitrosylation Transferase Translation regulation Ubl conjugation | MVKVGVNGFG | MVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLHYMVYMFQYDSTHGKFNGTVKAENGKLVINGKAITIFQERDPANIKWGDAGAEYVVESTGVFTTMEKAGAHLKGGAKRVIISAPSADAPMFVMGVNHEKYNNTLKIVSNASCTTNCLAPLAKVIHDHFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSVVDLTCRLEKPAKYDEIKKVVKQASEGPLKGILGYTEDQVVSCDFNSDTHSSTFDAGAGIALNDHFVKLISWYDNEFGYSN... | glucose metabolic process glycolytic process innate immune response microtubule cytoskeleton organization neuron apoptotic process peptidyl-cysteine S-trans-nitrosylation positive regulation of canonical NF-kappaB signal transduction positive regulation of type I interferon production protein stabilization regulation o... |
angiogenesis apoptotic process cell adhesion negative regulation of glial cell apoptotic process positive regulation of angiogenesis positive regulation of cardiac muscle hypertrophy positive regulation of cell adhesion positive regulation of cell migration positive regulation of dense core granule biogenesis positive ... | cytoplasm; cytosol; mitochondrial membrane; nucleus; perinuclear region of cytoplasm; plasma membrane | ATP binding diacylglycerol-dependent serine/threonine kinase activity protein serine kinase activity zinc ion binding | Oryctolagus cuniculus | Acetylation Angiogenesis Apoptosis ATP-binding Calcium Cell adhesion Cell membrane Cytoplasm Kinase Membrane Metal-binding Mitochondrion Nucleotide-binding Nucleus Phosphoprotein Reference proteome Repeat Serine/threonine-protein kinase Transferase Zinc Zinc-finger | MADVFPANDS | MADVFPANDSTASQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTDEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEDGNVELRQKFEKAKLGPAGNKVISP... | angiogenesis apoptotic process cell adhesion negative regulation of glial cell apoptotic process positive regulation of angiogenesis positive regulation of cardiac muscle hypertrophy positive regulation of cell adhesion positive regulation of cell migration positive regulation of dense core granule biogenesis positive ... |
brain development brain segmentation cell differentiation cell fate determination head morphogenesis midgut development positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II | nucleus | cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific protein heterodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding | Drosophila melanogaster | Alternative splicing Developmental protein DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation | MMDVSSMYGN | MMDVSSMYGNHPHHHHPHANAYDGYSTTTASAANASSYFAPQQHQPHLQLQQQQQHQHLQQPQQHLTYNGYESSSPGNYYPQQQAQLTPPPTSSHQVVQQHQQQQQAQQQQLYPHSHLFSPSAAEYGITTSTTTGNPGTPLHPSSHSPADSYYESDSVHSYYATAAVATVAPPSNSSPITAANASATSNTQQQQQQAAIISSENGMMYTNLDCMYPTAQAQAPVHGYAGQIEEKYAAVLHASYAPGMVLEDQDPMMQQATQSQMWHHQQHLAGSYALDAMDSLGMHAHMHHGLPHGHLGNLANNPHQQQPQVQQQQQQPH... | brain development brain segmentation cell differentiation cell fate determination head morphogenesis midgut development positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II nucleus cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor ... |
cellular response to cAMP cellular response to forskolin cholesterol metabolic process electron transport chain hormone biosynthetic process P450-containing electron transport chain steroid biosynthetic process | mitochondrial matrix; mitochondrion | 2 iron, 2 sulfur cluster binding electron transfer activity iron ion binding | Homo sapiens | 2Fe-2S 3D-structure Acetylation Cholesterol metabolism Electron transport Iron Iron-sulfur Lipid metabolism Metal-binding Mitochondrion Phosphoprotein Reference proteome Steroid metabolism Steroidogenesis Sterol metabolism Transit peptide Transport | MAAAGGARLL | MAAAGGARLLRAASAVLGGPAGRWLHHAGSRAGSSGLLRNRGPGGSAEASRSLSVSARARSSSEDKITVHFINRDGETLTTKGKVGDSLLDVVVENNLDIDGFGACEGTLACSTCHLIFEDHIYEKLDAITDEENDMLDLAYGLTDRSRLGCQICLTKSMDNMTVRVPETVADARQSIDVGKTS | cellular response to cAMP cellular response to forskolin cholesterol metabolic process electron transport chain hormone biosynthetic process P450-containing electron transport chain steroid biosynthetic process mitochondrial matrix; mitochondrion 2 iron, 2 sulfur cluster binding electron transfer activity iron ion bind... |
actin cytoskeleton organization cellular response to xenobiotic stimulus establishment of protein localization microvillus assembly negative regulation of cell migration positive regulation of protein autophosphorylation positive regulation of protein phosphorylation protein localization protein localization to plasma ... | cytosol; midbody; plasma membrane; recycling endosome; recycling endosome membrane; Schaffer collateral - CA1 synapse; synaptic membrane | G protein activity GDP binding GTP binding GTPase activity magnesium ion binding | Homo sapiens | 3D-structure Endosome Glycoprotein GTP-binding Hydrolase Lipoprotein Membrane Methylation Nucleotide-binding Palmitate Prenylation Reference proteome Ubl conjugation | MREYKVVVLG | MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLESEREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQMNYAAQPDKDDPCCSACNIQ | actin cytoskeleton organization cellular response to xenobiotic stimulus establishment of protein localization microvillus assembly negative regulation of cell migration positive regulation of protein autophosphorylation positive regulation of protein phosphorylation protein localization protein localization to plasma ... |
protein targeting SRP-dependent cotranslational protein targeting to membrane stringent response | cytoplasmic side of plasma membrane; cytosol; plasma membrane | ATP hydrolysis activity GTP binding GTPase activity protein homodimerization activity signal recognition particle binding | Escherichia coli | 3D-structure Cell inner membrane Cell membrane Cytoplasm Direct protein sequencing GTP-binding Hydrolase Membrane Nucleotide-binding Receptor Reference proteome | MAKEKKRGFF | MAKEKKRGFFSWLGFGQKEQTPEKETEVQNEQPVVEEIVQAQEPVKASEQAVEEQPQAHTEAEAETFAADVVEVTEQVAESEKAQPEAEVVAQPEPVVEETPEPVAIEREELPLPEDVNAEAVSPEEWQAEAETVEIVEAAEEEAAKEEITDEELETALAAEAAEEAVMVVPPAEEEQPVEEIAQEQEKPTKEGFFARLKRSLLKTKENLGSGFISLFRGKKIDDDLFEELEEQLLIADVGVETTRKIITNLTEGASRKQLRDAEALYGLLKEEMGEILAKVDEPLNVEGKAPFVILMVGVNGVGKTTTIGKLARQFEQQ... | protein targeting SRP-dependent cotranslational protein targeting to membrane stringent response cytoplasmic side of plasma membrane; cytosol; plasma membrane ATP hydrolysis activity GTP binding GTPase activity protein homodimerization activity signal recognition particle binding Escherichia coli 3D-structure Cell inne... |
cellular response to epidermal growth factor stimulus positive regulation by host of viral genome replication regulation of D-erythro-sphingosine kinase activity translation translational elongation | cortical actin cytoskeleton; cytoplasm; cytosol; cytosolic ribosome; myelin sheath; nucleolus; nucleus; plasma membrane; ribosome; ruffle membrane | calmodulin binding GTP binding GTPase activity heterocyclic compound binding identical protein binding kinase binding molecular adaptor activity mRNA binding protein kinase binding translation elongation factor activity tRNA binding | Mus musculus | Acetylation Cell membrane Cytoplasm Direct protein sequencing Elongation factor GTP-binding Hydrolase Isopeptide bond Membrane Methylation Nucleotide-binding Nucleus Phosphoprotein Protein biosynthesis Reference proteome Ubl conjugation | MGKEKTHINI | MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPPYSQKRYEEIVKEVSTYIKKIGYNPDTVAFVPISGWNGDNMLEPSANMPWFKGWKVTRKDGSASGTTLLEALDCILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKPGMVVTFAPVNVTTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDV... | cellular response to epidermal growth factor stimulus positive regulation by host of viral genome replication regulation of D-erythro-sphingosine kinase activity translation translational elongation cortical actin cytoskeleton; cytoplasm; cytosol; cytosolic ribosome; myelin sheath; nucleolus; nucleus; plasma membrane; ... |
amino acid catabolic process to alcohol via Ehrlich pathway fermentation | mitochondrion | alcohol dehydrogenase (NAD+) activity metal ion binding | Saccharomyces cerevisiae | Iron Metal-binding Mitochondrion NAD Oxidoreductase Reference proteome Zinc | MSSVTGFYIP | MSSVTGFYIPPISFFGEGALEETADYIKNKDYKKALIVTDPGIAAIGLSGRVQKMLEERDLNVAIYDKTQPNPNIANVTAGLKVLKEQNSEIVVSIGGGSAHDNAKAIALLATNGGEIGDYEGVNQSKKAALPLFAINTTAGTASEMTRFTIISNEEKKIKMAIIDNNVTPAVAVNDPSTMFGLPPALTAATGLDALTHCIEAYVSTASNPITDACALKGIDLINESLVAAYKDGKDKKARTDMCYAEYLAGMAFNNASLGYVHALAHQLGGFYHLPHGVCNAVLLPHVQEANMQCPKAKKRLGEIALHFGASQEDPEET... | amino acid catabolic process to alcohol via Ehrlich pathway fermentation mitochondrion alcohol dehydrogenase (NAD+) activity metal ion binding Saccharomyces cerevisiae Iron Metal-binding Mitochondrion NAD Oxidoreductase Reference proteome Zinc MSSVTGFYIP MSSVTGFYIPPISFFGEGALEETADYIKNKDYKKALIVTDPGIAAIGLSGRVQKMLEERDLNVA... |
apoptotic process granzyme-mediated programmed cell death signaling pathway killing of cells of another organism natural killer cell mediated cytotoxicity negative regulation of translation protein maturation proteolysis involved in protein catabolic process pyroptosis | cytolytic granule; cytoplasm; cytosol; extracellular region; immunological synapse; intracellular membrane-bounded organelle; membrane; nucleus | serine-type endopeptidase activity serine-type peptidase activity | Homo sapiens | 3D-structure Apoptosis Cytolysis Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Lysosome Protease Reference proteome Secreted Serine protease Signal Zymogen | MQPILLLLAF | MQPILLLLAFLLLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTMKRY | apoptotic process granzyme-mediated programmed cell death signaling pathway killing of cells of another organism natural killer cell mediated cytotoxicity negative regulation of translation protein maturation proteolysis involved in protein catabolic process pyroptosis cytolytic granule; cytoplasm; cytosol; extracellul... |
antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to interleukin-1 cellular response to interleukin-17 cellular response to tumor necrosis factor cellular response to type II interferon chemokine-mediated signaling pathway chemotaxis eosinophil chemotaxis G protein-coupled recept... | extracellular space | CCR chemokine receptor binding chemokine activity cytokine activity | Mus musculus | Alternative splicing Chemotaxis Cytokine Disulfide bond Glycoprotein Reference proteome Signal | MKPTAMALMC | MKPTAMALMCLLLAAVWIQDVDSKSMLTVSNSCCLNTLKKELPLKFIQCYRKMGSSCPDPPAVVFRLNKGRESCASTNKTWVQNHLKKVNPC | antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to interleukin-1 cellular response to interleukin-17 cellular response to tumor necrosis factor cellular response to type II interferon chemokine-mediated signaling pathway chemotaxis eosinophil chemotaxis G protein-coupled recept... |
actin filament polymerization activation of phospholipase A2 activity activation of phospholipase C activity angiogenesis antibacterial humoral response antimicrobial humoral immune response mediated by antimicrobial peptide cell differentiation defense response to Gram-positive bacterium diacylglycerol biosynthetic pr... | angiogenin-PRI complex; basement membrane; cytoplasmic vesicle; extracellular space; growth cone; neuronal cell body; nucleolus; nucleus | actin binding copper ion binding DNA binding endonuclease activity heparin binding RNA nuclease activity signaling receptor binding | Bos taurus | 3D-structure Angiogenesis Cytoplasmic vesicle Developmental protein Differentiation Direct protein sequencing Disulfide bond DNA-binding Endonuclease Hydrolase Nuclease Nucleus Protein synthesis inhibitor Reference proteome Secreted Signal Stress response | MVMVLSPLLL | MVMVLSPLLLVFILGLGLTPVAPAQDDYRYIHFLTQHYDAKPKGRNDEYCFNMMKNRRLTRPCKDRNTFIHGNKNDIKAICEDRNGQPYRGDLRISKSEFQITICKHKGGSSRPPCRYGATEDSRVIVVGCENGLPVHFDESFITPRH | actin filament polymerization activation of phospholipase A2 activity activation of phospholipase C activity angiogenesis antibacterial humoral response antimicrobial humoral immune response mediated by antimicrobial peptide cell differentiation defense response to Gram-positive bacterium diacylglycerol biosynthetic pr... |
chemotaxis defense response to virus innate immune response in mucosa RNA catabolic process | azurophil granule lumen; extracellular exosome; extracellular region; extracellular space | lyase activity nucleic acid binding ribonuclease A activity RNA nuclease activity | Homo sapiens | 3D-structure Chemotaxis Direct protein sequencing Disulfide bond Endonuclease Glycoprotein Hydrolase Lyase Lysosome Nitration Nuclease Reference proteome Signal | MVPKLFTSQI | MVPKLFTSQICLLLLLGLLAVEGSLHVKPPQFTWAQWFETQHINMTSQQCTNAMQVINNYQRRCKNQNTFLLTTFANVVNVCGNPNMTCPSNKTRKNCHHSGSQVPLIHCNLTTPSPQNISNCRYAQTPANMFYIVACDNRDQRRDPPQYPVVPVHLDRII | chemotaxis defense response to virus innate immune response in mucosa RNA catabolic process azurophil granule lumen; extracellular exosome; extracellular region; extracellular space lyase activity nucleic acid binding ribonuclease A activity RNA nuclease activity Homo sapiens 3D-structure Chemotaxis Direct protein sequ... |
cellular response to interferon-alpha cilium assembly immune system development regulation of gene expression response to UV smoothened signaling pathway transcription by RNA polymerase III | cytosol; nuclear body; nucleoplasm; ribonucleoprotein complex | metal ion binding RNA binding U2 snRNA binding | Homo sapiens | Acetylation Alternative splicing Cilium biogenesis/degradation Cytoplasm Direct protein sequencing Metal-binding Phosphoprotein Reference proteome Repeat Ribonucleoprotein RNA-binding | MEESVNQMQP | MEESVNQMQPLNEKQIANSQDGYVWQVTDMNRLHRFLCFGSEGGTYYIKEQKLGLENAEALIRLIEDGRGCEVIQEIKSFSQEGRTTKQEPMLFALAICSQCSDISTKQAAFKAVSEVCRIPTHLFTFIQFKKDLKESMKCGMWGRALRKAIADWYNEKGGMALALAVTKYKQRNGWSHKDLLRLSHLKPSSEGLAIVTKYITKGWKEVHELYKEKALSVETEKLLKYLEAVEKVKRTRDELEVIHLIEEHRLVREHLLTNHLKSKEVWKALLQEMPLTALLRNLGKMTANSVLEPGNSEVSLVCEKLCNEKLLKKARIH... | cellular response to interferon-alpha cilium assembly immune system development regulation of gene expression response to UV smoothened signaling pathway transcription by RNA polymerase III cytosol; nuclear body; nucleoplasm; ribonucleoprotein complex metal ion binding RNA binding U2 snRNA binding Homo sapiens Acetylat... |
cellular response to extracellular stimulus cytokine-mediated signaling pathway female pregnancy gene expression in utero embryonic development inflammatory response learning negative regulation of cell population proliferation placenta blood vessel development positive regulation of apoptotic process positive regulati... | nucleoplasm; nucleus; presynaptic membrane; RNA polymerase II transcription regulator complex | DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific promoter-specific chromatin binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-... | Rattus norvegicus | DNA-binding Nucleus Phosphoprotein Reference proteome | MYRDFGEPGP | MYRDFGEPGPSSGAGSAYGRPAQPQQAQTQTVQQQKFHLVPSINAVSGSQELQWMVQPHFLGPSGYPRPLTYPQYSPPQPRPGVIRALGPPPGVRRRPCEQISPEEEERRRVRRERNKLAAAKCRNRRKELTDFLQAETDKLEDEKSGLQREIEELQKQKERLELVLEAHRPICKIPEEDKKDTGGTSSTSGAGSPPGPCRPVPCISLSPGPVLEPEALHTPTLMTTPSLTPFTPSLVFTYPSTPEPCSSAHRKSSSSSGDPSSDPLGSPTLLAL | cellular response to extracellular stimulus cytokine-mediated signaling pathway female pregnancy gene expression in utero embryonic development inflammatory response learning negative regulation of cell population proliferation placenta blood vessel development positive regulation of apoptotic process positive regulati... |
positive regulation of translation positive regulation of translational elongation positive regulation of translational termination translational elongation | endoplasmic reticulum membrane; nucleus | ribosome binding RNA binding translation elongation factor activity | Oryctolagus cuniculus | 3D-structure Acetylation Cytoplasm Direct protein sequencing Elongation factor Endoplasmic reticulum Hypusine Membrane Nucleus Protein biosynthesis Reference proteome RNA-binding | MADDLDFETG | MADDLDFETGDAGASATFPMQCSALRKNGFVVLKGRPCKIVEMSTSKTGKHGHAKVHLVGIDIFTGKKYEDICPSTHNMDVPNIKRNDFQLIGIQDGYLSLLQDSGEVREDLRLPEGDLGKEIEQKYDSGEEILITVLSAMTEEAAVAIKAMAK | positive regulation of translation positive regulation of translational elongation positive regulation of translational termination translational elongation endoplasmic reticulum membrane; nucleus ribosome binding RNA binding translation elongation factor activity Oryctolagus cuniculus 3D-structure Acetylation Cytoplas... |
B cell proliferation bone resorption cytokine-mediated signaling pathway extrinsic apoptotic signaling pathway homeostasis of number of cells within a tissue immune response negative regulation of extrinsic apoptotic signaling pathway negative regulation of extrinsic apoptotic signaling pathway in absence of ligand org... | extracellular region; extracellular space | cytokine activity growth factor activity interleukin-7 receptor binding | Mus musculus | Cytokine Direct protein sequencing Disulfide bond Glycoprotein Growth factor Reference proteome Secreted Signal | MFHVSFRYIF | MFHVSFRYIFGIPPLILVLLPVTSSECHIKDKEGKAYESVLMISIDELDKMTGTDSNCPNNEPNFFRKHVCDDTKEAAFLNRAARKLKQFLKMNISEEFNVHLLTVSQGTQTLVNCTSKEEKNVKEQKKNDACFLKRLLREIKTCWNKILKGSI | B cell proliferation bone resorption cytokine-mediated signaling pathway extrinsic apoptotic signaling pathway homeostasis of number of cells within a tissue immune response negative regulation of extrinsic apoptotic signaling pathway negative regulation of extrinsic apoptotic signaling pathway in absence of ligand org... |
DNA damage response DNA repair fumarate metabolic process homeostasis of number of cells within a tissue malate metabolic process positive regulation of cold-induced thermogenesis positive regulation of double-strand break repair via nonhomologous end joining regulation of arginine metabolic process tricarboxylic acid ... | chromosome; cytosol; mitochondrial matrix; mitochondrion; nucleus; tricarboxylic acid cycle enzyme complex | fumarate hydratase activity | Sus scrofa | Acetylation Alternative initiation Chromosome Cytoplasm Direct protein sequencing DNA damage DNA repair Lyase Mitochondrion Nucleus Phosphoprotein Reference proteome Transit peptide Tricarboxylic acid cycle | MDRALRLLAR | MDRALRLLARSRCLSRVPASAPGPGPGSSPSGVSRLLLRPPNAARMASQNSFRIEYDTFGELKVPNDKYYGAQTVRSTMNFKIGGVTERMPIPVIKAFGILKRAAAEVNQDYGLDPKIANAIMKAADEVAEGKLNDHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKKPVHPNDHVNKSQSSNDTFPTAMHIAAAVEVHEALLPGLQKLHDALDAKSREFAQIIKIGRTHTQDAVPLTLGQEFSGYVQQVKYAITRIKAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAALTGLPFVTAPNKFEALAAH... | DNA damage response DNA repair fumarate metabolic process homeostasis of number of cells within a tissue malate metabolic process positive regulation of cold-induced thermogenesis positive regulation of double-strand break repair via nonhomologous end joining regulation of arginine metabolic process tricarboxylic acid ... |
cellular respiration mitochondrial electron transport, cytochrome c to oxygen proton transmembrane transport | mitochondrial membrane; mitochondrial respiratory chain complex IV; mitochondrion | oxidoreductase activity | Saccharomyces cerevisiae | 3D-structure Direct protein sequencing Membrane Mitochondrion Mitochondrion inner membrane Oxidoreductase Reference proteome Transmembrane Transmembrane helix | MANKVIQLQK | MANKVIQLQKIFQSSTKPLWWRHPRSALYLYPFYAIFAVAVVTPLLYIPNAIRGIKAKKA | cellular respiration mitochondrial electron transport, cytochrome c to oxygen proton transmembrane transport mitochondrial membrane; mitochondrial respiratory chain complex IV; mitochondrion oxidoreductase activity Saccharomyces cerevisiae 3D-structure Direct protein sequencing Membrane Mitochondrion Mitochondrion inn... |
cellular respiration generation of precursor metabolites and energy mitochondrial electron transport, cytochrome c to oxygen | mitochondrial inner membrane; mitochondrial membrane; mitochondrial respiratory chain complex IV; mitochondrion; respiratory chain complex IV | cytochrome-c oxidase activity | Homo sapiens | 3D-structure Direct protein sequencing Membrane Mitochondrion Mitochondrion inner membrane Primary mitochondrial disease Reference proteome Transit peptide Transmembrane Transmembrane helix | MSVLTPLLLR | MSVLTPLLLRGLTGSARRLPVPRAKIHSLPPEGKLGIMELAVGLTSCFVTFLLPAGWILSHLETYRRPE | cellular respiration generation of precursor metabolites and energy mitochondrial electron transport, cytochrome c to oxygen mitochondrial inner membrane; mitochondrial membrane; mitochondrial respiratory chain complex IV; mitochondrion; respiratory chain complex IV cytochrome-c oxidase activity Homo sapiens 3D-structu... |
establishment of ommatidial planar polarity positive regulation of transcription by RNA polymerase II R2/R5 cell differentiation R2/R5 cell fate commitment regulation of transcription by RNA polymerase II response to stimulus visual perception | nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding | Drosophila melanogaster | Developmental protein DNA-binding Homeobox Nucleus Reference proteome Sensory transduction Transcription Transcription regulation Vision | MQRHKVEIGS | MQRHKVEIGSPDGSPGIKRSDSLDPIANTTILSVPQRPSSPRQFFERLYGHLETRSSENGEIDVGTHAHKPPPCDTPYHSDGGSVSSPDISISDERTSLAAYPAYDFYGHAKDYPQHPSQQHQQHHHHHHHPPQLVHQKLSYVSPPPAIAAGGAANPVLPHAFPAGFPSDPHFSAGFSAFLARRRRKEGRQRRQRTTFSTEQTLRLEVEFHRNEYISRSRRFELAETLRLTETQIKIWFQNRRAKDKRIEKAQIDQHYRNFVVANGFMSSIMGQAATTMPPGGVTGGVAVGVGLNYYAAAATPAALPKDNTQDANFIDID... | establishment of ommatidial planar polarity positive regulation of transcription by RNA polymerase II R2/R5 cell differentiation R2/R5 cell fate commitment regulation of transcription by RNA polymerase II response to stimulus visual perception nucleus DNA-binding transcription factor activity, RNA polymerase II-specifi... |
negative regulation of viral genome replication response to corticosterone | extracellular region; extracellular space; protein-containing complex | ion channel inhibitor activity peptidase inhibitor activity potassium channel inhibitor activity protease binding serine-type endopeptidase inhibitor activity | Gallus gallus | Allergen Alternative splicing Antimicrobial Direct protein sequencing Disulfide bond Glycoprotein Protease inhibitor Reference proteome Repeat Secreted Serine protease inhibitor | MTDWVLHHKV | MTDWVLHHKVGPLDMTTRYIFPLLPLPFLPHSESKRAVCAPRCSAMRTARQFVQVALALCCFADIAFGIEVNCSLYASGIGKDGTSWVACPRNLKPVCGTDGSTYSNECGICLYNREHGANVEKEYDGECRPKHVTIDCSPYLQVVRDGNTMVACPRILKPVCGSDSFTYDNECGICAYNAEHHTNISKLHDGECKLEIGSVDCSKYPSTVSKDGRTLVACPRILSPVCGTDGFTYDNECGICAHNAEQRTHVSKKHDGKCRQEIPEIDCDQYPTRKTTGGKLLVRCPRILLPVCGTDGFTYDNECGICAHNAQHGTEVK... | negative regulation of viral genome replication response to corticosterone extracellular region; extracellular space; protein-containing complex ion channel inhibitor activity peptidase inhibitor activity potassium channel inhibitor activity protease binding serine-type endopeptidase inhibitor activity Gallus gallus Al... |
nuclear capsid assembly proteolysis viral release from host cell | host cell cytoplasm; host cell nucleus | identical protein binding serine-type endopeptidase activity | Human herpesvirus 1 | Alternative promoter usage Direct protein sequencing Host cytoplasm Host nucleus Hydrolase Phosphoprotein Protease Reference proteome Serine protease Viral capsid assembly Viral release from host cell | MAADAPGDRM | MAADAPGDRMEEPLPDRAVPIYVAGFLALYDSGDSGELALDPDTVRAALPPDNPLPINVDHRAGCEVGRVLAVVDDPRGPFFVGLIACVQLERVLETAASAAIFERRGPPLSREERLLYLITNYLPSVSLATKRLGGEAHPDRTLFAHVALCAIGRRLGTIVTYDTGLDAAIAPFRHLSPASREGARRLAAEAELALSGRTWAPGVEALTHTLLSTAVNNMMLRDRWSLVAERRRQAGIAGHTYLQASEKFKMWGAEPVSAPARGYKNGAPESTDIPPGSIAAAPQGDRCPIVRQRGVALSPVLPPMNPVPTSGTPAPAP... | nuclear capsid assembly proteolysis viral release from host cell host cell cytoplasm; host cell nucleus identical protein binding serine-type endopeptidase activity Human herpesvirus 1 Alternative promoter usage Direct protein sequencing Host cytoplasm Host nucleus Hydrolase Phosphoprotein Protease Reference proteome... |
bidirectional double-stranded viral DNA replication DNA replication | DNA polymerase complex; host cell nucleus | DNA binding DNA polymerase processivity factor activity | Human herpesvirus 1 | 3D-structure DNA replication DNA-binding Host nucleus Reference proteome | MTDSPGGVAP | MTDSPGGVAPASPVEDASDASLGQPEEGAPCQVVLQGAELNGILQAFAPLRTSLLDSLLVMGDRGILIHNTIFGEQVFLPLEHSQFSRYRWRGPTAAFLSLVDQKRSLLSVFRANQYPDLRRVELAITGQAPFRTLVQRIWTTTSDGEAVELASETLMKRELTSFVVLVPQGTPDVQLRLTRPQLTKVLNATGADSATPTTFELGVNGKFSVFTTSTCVTFAAREEGVSSSTSTQVQILSNALTKAGQAAANAKTVYGENTHRTFSVVVDDCSMRAVLRRLQVGGGTLKFFLTTPVPSLCVTATGPNAVSAVFLLKPQKI... | bidirectional double-stranded viral DNA replication DNA replication DNA polymerase complex; host cell nucleus DNA binding DNA polymerase processivity factor activity Human herpesvirus 1 3D-structure DNA replication DNA-binding Host nucleus Reference proteome MTDSPGGVAP MTDSPGGVAPASPVEDASDASLGQPEEGAPCQVVLQGAELNGILQAFA... |
induction by virus of host NF-kappaB cascade perturbation by virus of host G1/S transition checkpoint regulation of DNA-templated transcription suppression by virus of host mRNA processing | host cell cytoplasm; host cell nucleus | metal ion binding RNA binding | Human herpesvirus 1 | 3D-structure Activation of host NF-kappa-B by virus Activator Early protein Eukaryotic host gene expression shutoff by virus G1/S host cell cycle checkpoint dysregulation by virus Host cytoplasm Host gene expression shutoff by virus Host mRNA suppression by virus Host nucleus Host-virus interaction Inhibition of host p... | MATDIDMLID | MATDIDMLIDLGLDLSDSDLDEDPPEPAESRRDDLESDSSGECSSSDEDMEDPHGEDGPEPILDAARPAVRPSRPEDPGVPSTQTPRPTERQGPNDPQPAPHSVWSRLGARRPSCSPEQHGGKVARLQPPPTKAQPARGGRRGRRRGRGRGGPGAADGLSDPRRRAPRTNRNPGGPRPGAGWTDGPGAPHGEAWRGSEQPDPPGGQRTRGVRQAPPPLMTLAIAPPPADPRAPAPERKAPAADTIDATTRLVLRSISERAAVDRISESFGRSAQVMHDPFGGQPFPAANSPWAPVLAGQGGPFDAETRRVSWETLVAHGP... | induction by virus of host NF-kappaB cascade perturbation by virus of host G1/S transition checkpoint regulation of DNA-templated transcription suppression by virus of host mRNA processing host cell cytoplasm; host cell nucleus metal ion binding RNA binding Human herpesvirus 1 3D-structure Activation of host NF-kappa... |
cell differentiation male meiosis I mitotic cell cycle positive regulation of DNA-templated transcription positive regulation of piRNA transcription positive regulation of transcription by RNA polymerase II siRNA-mediated retrotransposon silencing by heterochromatin formation spermatogenesis | nucleoplasm; nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding | Homo sapiens | Acetylation Activator Alternative splicing Differentiation DNA-binding Isopeptide bond Nucleus Reference proteome Repeat Spermatogenesis Transcription Transcription regulation Ubl conjugation | MAKRSRSEDE | MAKRSRSEDEDDDLQYADHDYEVPQQKGLKKLWNRVKWTRDEDDKLKKLVEQHGTDDWTLIASHLQNRSDFQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSLIAKHLKGRIGKQCRERWHNHLNPEVKKSSWTEEEDRIIYEAHKRLGNRWAEIAKLLPGRTDNSIKNHWNSTMRRKVEQEGYLQDGIKSERSSSKLQHKPCAAMDHMQTQNQFYIPVQIPGYQYVSPEGNCIEHVQPTSAFIQQPFIDEDPDKEKKIKELEMLLMSAENEVRRKRIPSQPGSFSSWSGSFLMDDNMSNTLNSLDEHTSE... | cell differentiation male meiosis I mitotic cell cycle positive regulation of DNA-templated transcription positive regulation of piRNA transcription positive regulation of transcription by RNA polymerase II siRNA-mediated retrotransposon silencing by heterochromatin formation spermatogenesis nucleoplasm; nucleus DNA-bi... |
cellular response to leukemia inhibitory factor mitotic cell cycle mitotic spindle assembly positive regulation of neuron apoptotic process positive regulation of transcription by RNA polymerase II | cytosol; Myb complex; nucleoplasm; nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Homo sapiens | 3D-structure Alternative splicing DNA-binding Isopeptide bond Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation Ubl conjugation | MSRRTRCEDL | MSRRTRCEDLDELHYQDTDSDVPEQRDSKCKVKWTHEEDEQLRALVRQFGQQDWKFLASHFPNRTDQQCQYRWLRVLNPDLVKGPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGRLGKQCRERWHNHLNPEVKKSCWTEEEDRIICEAHKVLGNRWAEIAKMLPGRTDNAVKNHWNSTIKRKVDTGGFLSESKDCKPPVYLLLELEDKDGLQSAQPTEGQGSLLTNWPSVPPTIKEEENSEEELAAATTSKEQEPIGTDLDAVRTPEPLEEFPKREDQEGSPPETSLPYKWVVEAANLLIPAVGSSLSEALDLIESDPD... | cellular response to leukemia inhibitory factor mitotic cell cycle mitotic spindle assembly positive regulation of neuron apoptotic process positive regulation of transcription by RNA polymerase II cytosol; Myb complex; nucleoplasm; nucleus DNA-binding transcription activator activity, RNA polymerase II-specific DNA-bi... |
aorta development cardiac muscle contraction diaphragm contraction glucose metabolic process glycogen catabolic process glycophagy heart morphogenesis locomotory behavior lysosome organization maltose metabolic process muscle cell cellular homeostasis neuromuscular process controlling balance neuromuscular process cont... | autolysosome lumen; azurophil granule membrane; extracellular exosome; ficolin-1-rich granule membrane; intracellular membrane-bounded organelle; lysosomal lumen; lysosomal membrane; lysosome; membrane; plasma membrane; tertiary granule membrane | alpha-1,4-glucosidase activity alpha-glucosidase activity carbohydrate binding maltose alpha-glucosidase activity | Homo sapiens | 3D-structure Direct protein sequencing Disease variant Disulfide bond Glycogen storage disease Glycoprotein Glycosidase Hydrolase Lysosome Membrane Phosphoprotein Reference proteome Signal | MGVRHPPCSH | MGVRHPPCSHRLLAVCALVSLATAALLGHILLHDFLLVPRELSGSSPVLEETHPAHQQGASRPGPRDAQAHPGRPRAVPTQCDVPPNSRFDCAPDKAITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFPPSYPSYKLENLSSSEMGYTATLTRTTPTFFPKDILTLRLDVMMETENRLHFTIKDPANRRYEVPLETPHVHSRAPSPLYSVEFSEEPFGVIVRRQLDGRVLLNTTVAPLFFADQFLQLSTSLPSQYITGLAEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDGGSAHGVFLLNSNAMDV... | aorta development cardiac muscle contraction diaphragm contraction glucose metabolic process glycogen catabolic process glycophagy heart morphogenesis locomotory behavior lysosome organization maltose metabolic process muscle cell cellular homeostasis neuromuscular process controlling balance neuromuscular process cont... |
viral budding via host ESCRT complex | viral nucleocapsid | DNA binding nucleotide binding structural constituent of virion zinc ion binding | Mouse mammary tumor virus | 3D-structure Capsid protein DNA-binding Host-virus interaction Lipoprotein Metal-binding Myristate Nucleotide-binding Phosphoprotein Reference proteome Repeat Ribosomal frameshifting Viral budding Viral budding via the host ESCRT complexes Viral matrix protein Viral nucleoprotein Viral release from host cell Virion Zin... | MGVSGSKGQK | MGVSGSKGQKLFVSVLQRLLSERGLHVKESSAIEFYQFLIKVSPWFPEEGGLNLQDWKRVGREMKRYAAEHGTDSIPKQAYPIWLQLREILTEQSDLVLLSAEAKSVTEEELEEGLTGLLSTSSQEKTYGTRGTAYAEIDTEVDKLSEHIYDEPYEEKEKADKNEEKDHVRKIKKVVQRKENSEGKRKEKDSKAFLATDWNDDDLSPEDWDDLEEQAAHYHDDDELILPVKRKVVKKKPQALRRKPLPPVGFAGAMAEAREKGDLTFTFPVVFMGESDEDDTPVWEPLPLKTLKELQSAVRTMGPSAPYTLQVVDMVASQ... | viral budding via host ESCRT complex viral nucleocapsid DNA binding nucleotide binding structural constituent of virion zinc ion binding Mouse mammary tumor virus 3D-structure Capsid protein DNA-binding Host-virus interaction Lipoprotein Metal-binding Myristate Nucleotide-binding Phosphoprotein Reference proteome Repe... |
viral budding via host ESCRT complex | host cell late endosome membrane; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid | RNA binding structural constituent of virion zinc ion binding | Feline leukemia virus | Alternative initiation Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Phosphoprotein RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral matrix protein Viral nucleoprotein Viral release from host cel... | MGQTITTPLS | MGQTITTPLSLTLDHWSEVRARAHNQGVEVRKKKWITLCEAEWVMMNVGWPREGTFSLDNISQVEKKIFAPGPYGHPDQVPYITTWRSLATDPPSWVRPFLPPPKPPTPLPQPLSPQPSAPLTSSLYPVLPKSDPPKPPVLPPDPSSPLIDLLTEEPPPYPGGHGPPPSGPRTPTASPIASRLRERRENPAEESQALPLREGPNNRPQYWPFSASDLYNWKSHNPPFSQDPVALTNLIESILVTHQPTWDDCQQLLQALLTGEERQRVLLEARKQVPGEDGRPTQLPNVIDETFPLTRPNWDFATPAGREHLRLYRQLLL... | viral budding via host ESCRT complex host cell late endosome membrane; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid RNA binding structural constituent of virion zinc ion binding Feline leukemia virusAlternative initiation Capsid protein Host cell membrane Host cytoplasm Host endosom... |
proteolysis viral process | viral nucleocapsid | aspartic-type endopeptidase activity DNA binding dUTP diphosphatase activity structural constituent of virion zinc ion binding | Mouse mammary tumor virus | Aspartyl protease Capsid protein DNA-binding Hydrolase Lipoprotein Magnesium Metal-binding Myristate Protease Reference proteome Ribosomal frameshifting Viral matrix protein Viral nucleoprotein Virion Zinc Zinc-finger | MGVSGSKGQK | MGVSGSKGQKLFVSVLQRLLSERGLHVKESSAIEFYQFLIKVSPWFPEEGGLNLQDWKRVGREMKRYAAEHGTDSIPKQAYPIWLQLREILTEQSDLVLLSAEAKSVTEEELEEGLTGLLSTSSQEKTYGTRGTAYAEIDTEVDKLSEHIYDEPYEEKEKADKNEEKDHVRKIKKVVQRKENSEGKRKEKDSKAFLATDWNDDDLSPEDWDDLEEQAAHYHDDDELILPVKRKVVKKKPQALRRKPLPPVGFAGAMAEAREKGDLTFTFPVVFMGESDEDDTPVWEPLPLKTLKELQSAVRTMGPSAPYTLQVVDMVASQ... | proteolysis viral process viral nucleocapsid aspartic-type endopeptidase activity DNA binding dUTP diphosphatase activity structural constituent of virion zinc ion binding Mouse mammary tumor virus Aspartyl protease Capsid protein DNA-binding Hydrolase Lipoprotein Magnesium Metal-binding Myristate Protease Reference p... |
proteolysis suppression by virus of host gene expression | viral nucleocapsid | aspartic-type endopeptidase activity nucleic acid binding structural molecule activity zinc ion binding | Human T-cell leukemia virus 1 | 3D-structure Aspartyl protease Capsid protein Direct protein sequencing Eukaryotic host gene expression shutoff by virus Eukaryotic host translation shutoff by virus Host gene expression shutoff by virus Host-virus interaction Hydrolase Lipoprotein Metal-binding Myristate Phosphoprotein Protease Repeat Ribosomal frames... | MGQIFSRSAS | MGQIFSRSASPIPRPPRGLAAHHWLNFLQAAYRLEPGPSSYDFHQLKKFLKIALETPARICPINYSLLASLLPKGYPGRVNEILHILIQTQAQIPSRPAPPPPSSPTHDPPDSDPQIPPPYVEPTAPQVLPVMHPHGAPPNHRPWQMKDLQAIKQEVSQAAPGSPQFMQTIRLAVQQFDPTAKDLQDLLQYLCSSLVASLHHQQLDSLISEAETRGITGYNPLAGPLRVQANNPQQQGLRREYQQLWLAAFAALPGSAKDPSWASILQGLEEPYHAFVERLNIALDNGLPEGTPKDPILRSLAYSNANKECQKLLQARGH... | proteolysis suppression by virus of host gene expression viral nucleocapsid aspartic-type endopeptidase activity nucleic acid binding structural molecule activity zinc ion binding Human T-cell leukemia virus 1 3D-structure Aspartyl protease Capsid protein Direct protein sequencing Eukaryotic host gene expression shuto... |
calcium-mediated signaling using intracellular calcium source cellular response to amyloid-beta cellular response to copper ion positive regulation of neuron apoptotic process positive regulation of peptidyl-tyrosine phosphorylation protein destabilization protein homooligomerization | cell surface; cytosol; dendrite; Golgi apparatus; inclusion body; membrane raft; nuclear membrane; plasma membrane; side of membrane | amyloid-beta binding copper ion binding cuprous ion binding G-quadruplex RNA binding identical protein binding microtubule binding molecular condensate scaffold activity protein-containing complex binding type 5 metabotropic glutamate receptor binding | Bos taurus | 3D-structure Amyloid Cell membrane Copper Direct protein sequencing Disulfide bond Glycoprotein Golgi apparatus GPI-anchor Lipoprotein Membrane Metal-binding Prion Reference proteome Repeat Signal Zinc | MVKSHIGSWI | MVKSHIGSWILVLFVAMWSDVGLCKKRPKPGGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGGWGQGGTHGQWNKPSKPKTNMKHVAGAAAAGAVVGGLGGYMLGSAMSRPLIHFGSDYEDRYYRENMHRYPNQVYYRPVDQYSNQNNFVHDCVNITVKEHTVTTTTKGENFTETDIKMMERVVEQMCITQYQRESQAYYQRGASVILFSSPPVILLISFLIFLIVG | calcium-mediated signaling using intracellular calcium source cellular response to amyloid-beta cellular response to copper ion positive regulation of neuron apoptotic process positive regulation of peptidyl-tyrosine phosphorylation protein destabilization protein homooligomerization cell surface; cytosol; dendrite; Go... |
anterior/posterior pattern specification bone marrow development definitive hemopoiesis embryonic skeletal system morphogenesis hematopoietic stem cell differentiation hematopoietic stem cell proliferation hemopoiesis morphogenesis of an epithelial sheet negative regulation of transcription by RNA polymerase II positiv... | centrosome; nucleoplasm | DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Mus musculus | Developmental protein DNA-binding Homeobox Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MAMSSFLINS | MAMSSFLINSNYVDPKFPPCEEYSQSDYLPSDHSPGYYAGGQRRESGFQPEAAFGRRAPCTVQRYAACRDPGPPPPPPPPPPPPPPGLSPRAPVQPTAGALLPEPGQRSEAVSSSPPPPPCAQNPLHPSPSHSACKEPVVYPWMRKVHVSTVNPNYAGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQIKIWFQNRRMKWKKDHKLPNTKIRSGGTAGAAGGPPGRPNGGPPAL | anterior/posterior pattern specification bone marrow development definitive hemopoiesis embryonic skeletal system morphogenesis hematopoietic stem cell differentiation hematopoietic stem cell proliferation hemopoiesis morphogenesis of an epithelial sheet negative regulation of transcription by RNA polymerase II positiv... |
adherens junction organization calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules cell morphogenesis cell-cell adhesion cell-cell adhesion mediated by cadherin cell-cell junction assembly hair cycle process homophilic cell adhesion via plasma membrane adhesion molecules keratinization nega... | adherens junction; catenin complex; cell junction; cytoplasm; plasma membrane | cadherin binding calcium ion binding | Mus musculus | 3D-structure Calcium Cell adhesion Cell membrane Cleavage on pair of basic residues Glycoprotein Membrane Metal-binding Reference proteome Repeat Signal Transmembrane Transmembrane helix | MELLSGPHAF | MELLSGPHAFLLLLLQVCWLRSVVSEPYRAGFIGEAGVTLEVEGTDLEPSQVLGKVALAGQGMHHADNGDIIMLTRGTVQGGKDAMHSPPTRILRRRKREWVMPPIFVPENGKGPFPQRLNQLKSNKDRGTKIFYSITGPGADSPPEGVFTIEKESGWLLLHMPLDREKIVKYELYGHAVSENGASVEEPMNISIIVTDQNDNKPKFTQDTFRGSVLEGVMPGTSVMQVTATDEDDAVNTYNGVVAYSIHSQEPKEPHDLMFTIHKSTGTISVISSGLDREKVPEYRLTVQATDMDGEGSTTTAEAVVQILDANDNAPEF... | adherens junction organization calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules cell morphogenesis cell-cell adhesion cell-cell adhesion mediated by cadherin cell-cell junction assembly hair cycle process homophilic cell adhesion via plasma membrane adhesion molecules keratinization nega... |
cell differentiation regulation of DNA-templated transcription | nucleus | transcription cis-regulatory region binding | Zea mays | Activator DNA-binding Nucleus Reference proteome Repeat Transcription Transcription regulation | MGRRACCAKE | MGRRACCAKEGVKRGAWTSKEDDALAAYVKAHGEGKWREVPQKAGLRRCGKSCRLRWLNYLRPNIRRGNISYDEEDLIIRLHRLLGNRWSLIAGRLPGRTDNEIKNYWNSTLGRRAGAGAGAGGSWVVVAPDTGSHATPAATSGACETGQNSAAHRADPDSAGTTTTSAAAVWAPKAVRCTGGLFFFHRDTTPAHAGETATPMAGGGGGGGGEAGSSDDCSSAASVSLRVGSHDEPCFSGDGDGDWMDDVRALASFLESDEDWLRCQTAGQLA | cell differentiation regulation of DNA-templated transcription nucleus transcription cis-regulatory region binding Zea mays Activator DNA-binding Nucleus Reference proteome Repeat Transcription Transcription regulation MGRRACCAKE MGRRACCAKEGVKRGAWTSKEDDALAAYVKAHGEGKWREVPQKAGLRRCGKSCRLRWLNYLRPNIRRGNISYDEEDLIIRLHRLLGNRWS... |
cellular detoxification defense response to Gram-negative bacterium innate immune response negative regulation of cellular response to manganese ion positive regulation of cellular response to manganese ion | cytosol | glutathione transferase activity | Caenorhabditis elegans | Reference proteome Transferase | MTLKLTYFDI | MTLKLTYFDIHGLAEPIRLLLADKQVAYEDHRVTYEQWADIKPKMIFGQVPCLLSGDEEIVQSGAIIRHLARLNGLNGSNETETTFIDMFYEGLRDLHTKYTTMIYRNYEDGKAPYIKDVLPGELARLEKLFHTYKNGEHYVIGDKESYADYVLFEELDIHLILTPNALDGVPALKKFHERFAERPNIKAYLNKRAAINPPVNGNGKQ | cellular detoxification defense response to Gram-negative bacterium innate immune response negative regulation of cellular response to manganese ion positive regulation of cellular response to manganese ion cytosol glutathione transferase activity Caenorhabditis elegansReference proteome Transferase MTLKLTYFDI MTLKLTYF... |
adaptive immune response T cell activation T cell receptor signaling pathway | cell surface; external side of plasma membrane; plasma membrane; receptor complex | coreceptor activity MHC class I protein binding | Mus musculus | 3D-structure Adaptive immunity Disulfide bond Glycoprotein Immunity Immunoglobulin domain Membrane Reference proteome Signal Transmembrane Transmembrane helix | MQPWLWLVFS | MQPWLWLVFSMKLAALWSSSALIQTPSSLLVQTNHTAKMSCEVKSISKLTSIYWLRERQDPKDKYFEFLASWSSSKGVLYGESVDKKRNIILESSDSRRPFLSIMNVKPEDSDFYFCATVGSPKMVFGTGTKLTVVDVLPTTAPTKKTTLKMKKKKQCPFPHPETQKGLTCSLTTLSLLVVCILLLLAFLGVAVYFYCVRRRARIHFMKQFHK | adaptive immune response T cell activation T cell receptor signaling pathway cell surface; external side of plasma membrane; plasma membrane; receptor complex coreceptor activity MHC class I protein binding Mus musculus 3D-structure Adaptive immunity Disulfide bond Glycoprotein Immunity Immunoglobulin domain Membrane R... |
face morphogenesis leukocyte differentiation negative regulation of Schwann cell migration positive regulation of angiogenesis positive regulation of endothelial cell migration positive regulation of endothelial cell-matrix adhesion via fibronectin positive regulation of vasculogenesis Ras protein signal transduction r... | extracellular exosome; focal adhesion; plasma membrane | GDP binding GTP binding GTPase activity protein-containing complex binding | Homo sapiens | 3D-structure Cell membrane Direct protein sequencing GTP-binding Hydrolase Lipoprotein Membrane Methylation Nucleotide-binding Palmitate Prenylation Reference proteome | MSSGAASGTG | MSSGAASGTGRGRPRGGGPGPGDPPPSETHKLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIEDSYTKICSVDGIPARLDILDTAGQEEFGAMREQYMRAGHGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPVVLVGNKADLESQRQVPRSEASAFGASHHVAYFEASAKLRLNVDEAFEQLVRAVRKYQEQELPPSPPSAPRKKGGGCPCVLL | face morphogenesis leukocyte differentiation negative regulation of Schwann cell migration positive regulation of angiogenesis positive regulation of endothelial cell migration positive regulation of endothelial cell-matrix adhesion via fibronectin positive regulation of vasculogenesis Ras protein signal transduction r... |
chromosome organization viral DNA genome packaging | viral terminase, large subunit | ATP binding ATP hydrolysis activity endonuclease activity metal ion binding | Enterobacteria phage T3 | ATP-binding Endonuclease Hydrolase Magnesium Metal-binding Nuclease Nucleotide-binding Viral genome packaging Viral release from host cell | MSTQSNRNAL | MSTQSNRNALVVAQLKGDFVAFLFVLWKALNLPVPTKCQIDMAKVLANGDNKKFILQAFRGIGKSFITCAFVVWTLWRDPQLKILIVSASKERADLNSIFIKNIIDLLPFLDELKPSPGQRDSVISFDVGPAKPDHSPSVKSVGITGQLTGSRADIIIADDVEIPSNSATQGAREKLWTLVQEFRALLKPLPTSRVIYLGTPQTEMTLYKELEDNRGYTTIIWPALYPRSREEDLYYGERLAPMLREEFNDGFEMLQGQPTDPVRFDMEDLRERELEYGKAGFTLQFMLNPNLSDAEKYPLRLRDAIVCGLDFEKAPMHY... | chromosome organization viral DNA genome packaging viral terminase, large subunit ATP binding ATP hydrolysis activity endonuclease activity metal ion binding Enterobacteria phage T3 ATP-binding Endonuclease Hydrolase Magnesium Metal-binding Nuclease Nucleotide-binding Viral genome packaging Viral release from host cell... |
adaptive immune response antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response innate immune response positive regulation of T cell mediated cytotoxicity | cell surface; early endosome membrane; endoplasmic reticulum; ER to Golgi transport vesicle membrane; external side of plasma membrane; extracellular exosome; extracellular space; Golgi apparatus; Golgi membrane; lumenal side of endoplasmic reticulum membrane; membrane; MHC class I protein complex; phagocytic vesicle m... | peptide antigen binding signaling receptor binding TAP binding | Homo sapiens | 3D-structure Adaptive immunity Alternative splicing Cell membrane Disulfide bond Endoplasmic reticulum Glycoprotein Host-virus interaction Immunity Innate immunity Membrane MHC I Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix | MRVMAPRALL | MRVMAPRALLLLLSGGLALTETWACSHSMRYFDTAVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQADRVSLRNLRGYYNQSEDGSHTLQRMSGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTAAQITQRKLEAARAAEQLRAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGLQEPLTLSWEPSSQPTIPIMGIVAGLAVLVV... | adaptive immune response antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response innate immune response positive regulation of T cell mediated cytotoxicity cell su... |
acrosome matrix dispersal acrosome reaction activation of adenylate cyclase activity binding of sperm to zona pellucida penetration of zona pellucida response to steroid hormone single fertilization | acrosomal matrix; extracellular region; Golgi-associated vesicle; nucleus; protein-containing complex | amidase activity copper ion binding DNA binding fucose binding mannose binding protease binding serine-type endopeptidase activity serine-type peptidase activity zinc ion binding | Homo sapiens | Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Serine protease Signal Zymogen | MVEMLPTAIL | MVEMLPTAILLVLAVSVVAKDNATCDGPCGLRFRQNPQGGVRIVGGKAAQHGAWPWMVSLQIFTYNSHRYHTCGGSLLNSRWVLTAAHCFVGKNNVHDWRLVFGAKEITYGNNKPVKAPLQERYVEKIIIHEKYNSATEGNDIALVEITPPISCGRFIGPGCLPHFKAGLPRGSQSCWVAGWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQWYNGRVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALRMIQSATPPPPTTRPPPIRPPFSHPI... | acrosome matrix dispersal acrosome reaction activation of adenylate cyclase activity binding of sperm to zona pellucida penetration of zona pellucida response to steroid hormone single fertilization acrosomal matrix; extracellular region; Golgi-associated vesicle; nucleus; protein-containing complex amidase activity co... |
mating positive regulation of octopamine signaling pathway positive regulation of ovulation sexual reproduction sperm competition | cytoplasm; extracellular region; extracellular space | identical protein binding | Drosophila melanogaster | Behavior Cytoplasm Glycoprotein Reference proteome Secreted Signal | MNQILLCSPI | MNQILLCSPILLLLFTVASCDSEQQLDSAMHLKSDSTKSASLKNVAPKNDETQAKIAKDDVALKDAKKGDYIMDIDISDLPLDDYPINRSKSLKSSSIDLNNIPFNKGLDDFPAKEKNQGSNQSALKALQQRLLTEQNNSLLLRNHSIYLMKEIEARKTDIIKVRQLNLDLELELNTVNRRLLELNGQLQNTRKSTKPCKKRSSKDSAPPAANQFQEANVRNTYRNKYLTLLKELSQKINNEIAKVATDVPTETNPSQGNLPTL | mating positive regulation of octopamine signaling pathway positive regulation of ovulation sexual reproduction sperm competition cytoplasm; extracellular region; extracellular space identical protein binding Drosophila melanogaster Behavior Cytoplasm Glycoprotein Reference proteome Secreted Signal MNQILLCSPI MNQILLCSP... |
carbohydrate metabolic process macromolecule metabolic process | extracellular region | isoamylase activity metal ion binding | Pseudomonas amyloderamosa | 3D-structure Calcium Disulfide bond Glycosidase Hydrolase Metal-binding Secreted Signal | MKCPKILAAL | MKCPKILAALLGCAVLAGVPAMPAHAAINSMSLGASYDAQQANITFRVYSSQATRIVLYLYSAGYGVQESATYTLSPAGSGVWAVTVPVSSIKAAGITGAVYYGYRAWGPNWPYASNWGKGSQAGFVSDVDANGDRFNPNKLLLDPYAQEVSQDPLNPSNQNGNVFASGASYRTTDSGIYAPKGVVLVPSTQSTGTKPTRAQKDDVIYEVHVRGFTEQDTSIPAQYRGTYYGAGLKASYLASLGVTAVEFLPVQETQNDANDVVPNSDANQNYWGYMTENYFSPDRRYAYNKAAGGPTAEFQAMVQAFHNAGIKVYMDVV... | carbohydrate metabolic process macromolecule metabolic process extracellular region isoamylase activity metal ion binding Pseudomonas amyloderamosa3D-structure Calcium Disulfide bond Glycosidase Hydrolase Metal-binding Secreted Signal MKCPKILAAL MKCPKILAALLGCAVLAGVPAMPAHAAINSMSLGASYDAQQANITFRVYSSQATRIVLYLYSAGYGVQESATYT... |
apoptotic process cell cycle DNA damage response positive regulation of apoptotic process positive regulation of transcription by RNA polymerase II protein tetramerization regulation of transcription by RNA polymerase II | cytoplasm; mitochondrion; nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific metal ion binding promoter-specific chromatin binding RNA polymerase II cis-regulatory region sequence-specific DNA binding | Gallus gallus | Activator Apoptosis Cell cycle Cytoplasm DNA-binding Metal-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Tumor suppressor Zinc | MAEEMEPLLE | MAEEMEPLLEPTEVFMDLWSMLPYSMQQLPLPEDHSNWQELSPLEPSDPPPPPPPPPLPLAAAAPPPLNPPTPPRAAPSPVVPSTEDYGGDFDFRVGFVEAGTAKSVTCTYSPVLNKVYCRLAKPCPVQVRVGVAPPPGSSLRAVAVYKKSEHVAEVVRRCPHHERCGGGTDGLAPAQHLIRVEGNPQARYHDDETTKRHSVVVPYEPPEVGSDCTTVLYNFMCNSSCMGGMNRRPILTILTLEGPGGQLLGRRCFEVRVCACPGRDRKIEEENFRKRGGAGGVAKRAMSPPTEAPEPPKKRVLNPDNEIFYLQVRGRRR... | apoptotic process cell cycle DNA damage response positive regulation of apoptotic process positive regulation of transcription by RNA polymerase II protein tetramerization regulation of transcription by RNA polymerase II cytoplasm; mitochondrion; nucleus DNA-binding transcription factor activity, RNA polymerase II-spec... |
angiogenesis eosinophil chemotaxis induction of positive chemotaxis intracellular signal transduction MAPK cascade negative regulation of endothelial cell apoptotic process negative regulation of extrinsic apoptotic signaling pathway positive chemotaxis positive regulation of endothelial cell proliferation | dense core granule; extracellular space; neuronal dense core vesicle; secretory granule | chemoattractant activity cytokine activity | Rattus norvegicus | Calcium Cleavage on pair of basic residues Direct protein sequencing Phosphoprotein Reference proteome Secreted Signal Sulfation | MTESKAYRFG | MTESKAYRFGAVLLLIHLIFLVPGTEAASFQRNQLLQKEPDLRLENVQKFPSPEMIRALEYIEKLRQQAHREESSPDYNPYQGISVPLQLKENGEESHLAESSRDVLSEDEWMRIILEALRQAENEPPSALKENKPYALNLEKNFPVDTPDDYETQQWPERKLKHMRFPLMYEENSRENPFKRTNEIVEEQYTPQSLATLESVFQELGKLTGPSNQKRERVDEEQKLYTDDEDDVYKTNNIAYEDVVGGEDWSPMEEKIETQTQEEVRDSKENTEKNEQINEEMKRSGHLGLPDEGNRKESKDQLSEDASKVITYLRRLV... | angiogenesis eosinophil chemotaxis induction of positive chemotaxis intracellular signal transduction MAPK cascade negative regulation of endothelial cell apoptotic process negative regulation of extrinsic apoptotic signaling pathway positive chemotaxis positive regulation of endothelial cell proliferation dense core g... |
DNA replication DNA replication initiation DNA replication, synthesis of RNA primer | alpha DNA polymerase:primase complex; nuclear replication fork | ATP binding DNA primase activity metal ion binding | Saccharomyces cerevisiae | 3D-structure ATP-binding DNA replication DNA-directed RNA polymerase Metal-binding Nucleotide-binding Nucleotidyltransferase Primosome Reference proteome Transcription Transferase Zinc | MTNSVKTNGP | MTNSVKTNGPSSSDMEYYYKSLYPFKHIFNWLNHSPKPSRDMINREFAMAFRSGAYKRYNSFNSVQDFKAQIEKANPDRFEIGAIYNKPPRERDTLLKSELKALEKELVFDIDMDDYDAFRTCCSGAQVCSKCWKFISLAMKITNTALREDFGYKDFIWVFSGRRGAHCWVSDKRARALTDVQRRNVLDYVNVIRDRNTDKRLALKRPYHPHLARSLEQLKPFFVSIMLEEQNPWEDDQHAIQTLLPALYDKQLIDSLKKYWLDNPRRSSKEKWNDIDQIATSLFKGPKQDSHIIKLRECKEDLVLMTLYPKLDVEVTKQ... | DNA replication DNA replication initiation DNA replication, synthesis of RNA primer alpha DNA polymerase:primase complex; nuclear replication fork ATP binding DNA primase activity metal ion binding Saccharomyces cerevisiae 3D-structure ATP-binding DNA replication DNA-directed RNA polymerase Metal-binding Nucleotide-bi... |
histidine biosynthetic process | cytoplasm; cytosol | histidinol dehydrogenase activity NAD binding zinc ion binding | Salmonella typhimurium | Amino-acid biosynthesis Direct protein sequencing Histidine biosynthesis Manganese Metal-binding NAD Oxidoreductase Reference proteome Zinc | MSFNTLIDWN | MSFNTLIDWNSCSPEQQRALLTRPAISASDSITRTVSDILDNVKTRGDDALREYSAKFDKTEVTALRVTPEEIAAAGARLSDELKQAMTAAVKNIETFHSAQTLPPVDVETQPGVRCQQVTRPVSSVGLYIPGGSAPLFSTVLMLATPARIAGCQKVVLCSPPPIADEILYAAQLCGVQEIFNVGGAQAIAALAFGSESVPKVDKIFGPGNAFVTEAKRQVSQRLDGAAIDMPAGPSEVLVIADSGATPDFVASDLLSQAEHGPDSQVILLTPDADIARKVAEAVERQLAELPRADTARQALSASRLIVTKDLAQCVAIS... | histidine biosynthetic process cytoplasm; cytosol histidinol dehydrogenase activity NAD binding zinc ion binding Salmonella typhimurium Amino-acid biosynthesis Direct protein sequencing Histidine biosynthesis Manganese Metal-binding NAD Oxidoreductase Reference proteome Zinc MSFNTLIDWN MSFNTLIDWNSCSPEQQRALLTRPAISASDSIT... |
enterobactin biosynthetic process | cytosol; membrane | (2,3-dihydroxybenzoyl)adenylate synthase activity 2,3-dihydroxybenzoate-serine ligase activity acyltransferase activity ATP binding | Escherichia coli | 3D-structure Acyltransferase ATP-binding Enterobactin biosynthesis Ligase Membrane Nucleotide-binding Reference proteome Transferase | MSIPFTRWPE | MSIPFTRWPEEFARRYREKGYWQDLPLTDILTRHAASDSIAVIDGERQLSYRELNQAADNLACSLRRQGIKPGETALVQLGNVAELYITFFALLKLGVAPVLALFSHQRSELNAYASQIEPALLIADRQHALFSGDDFLNTFVTEHSSIRVVQLLNDSGEHNLQDAINHPAEDFTATPSPADEVAYFQLSGGTTGTPKLIPRTHNDYYYSVRRSVEICQFTQQTRYLCAIPAAHNYAMSSPGSLGVFLAGGTVVLAADPSATLCFPLIEKHQVNVTALVPPAVSLWLQALIEGESRAQLASLKLLQVGGARLSATLAARI... | enterobactin biosynthetic process cytosol; membrane (2,3-dihydroxybenzoyl)adenylate synthase activity 2,3-dihydroxybenzoate-serine ligase activity acyltransferase activity ATP binding Escherichia coli 3D-structure Acyltransferase ATP-binding Enterobactin biosynthesis Ligase Membrane Nucleotide-binding Reference proteom... |
female germ-line sex determination germ cell development negative regulation of peptidoglycan recognition protein signaling pathway oogenesis positive regulation of DNA endoreduplication positive regulation of stem cell differentiation protein deubiquitination protein K63-linked deubiquitination | cytosol | deubiquitinase activity mRNA binding serine-type peptidase activity | Drosophila melanogaster | Alternative splicing Cytoplasm Reference proteome | MDMQVQRPIT | MDMQVQRPITSGSRQAPDPYDQYLESRGLYRKHTARDASSLFRVIAEQMYDTQMLHYEIRLECVRFMTLKRRIFEKEIPGDFDSYMQDMSKPKTYGTMTELRAMSCLYRRNVILYEPYNMGTSVVFNRRYAENFRVFFNNENHFDSVYDVEYIERAAICQSIAFKLLYQKLFKLPDVSFAVEIMLHPHTFNWDRFNVEFDDKGYMVRIHCTDGRVFKLDLPGDTNCILENYKLCNFHSTNGNQSINARKGGRLEIKNQEERKASGSSGHEPNDLLPMCPNRLESCVRQLLDDGISPFPYKVAKSMDPYMYRNIEFDCWND... | female germ-line sex determination germ cell development negative regulation of peptidoglycan recognition protein signaling pathway oogenesis positive regulation of DNA endoreduplication positive regulation of stem cell differentiation protein deubiquitination protein K63-linked deubiquitination cytosol deubiquitinase ... |
MAPK cascade negative regulation of apoptotic process phosphorylation positive regulation of peptidyl-serine phosphorylation protein modification process regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of TOR signaling | cytosol; mitochondrion | ATP binding MAP kinase kinase kinase activity metal ion binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity | Homo sapiens | 3D-structure Alternative splicing ATP-binding Kinase Metal-binding Nucleotide-binding Phosphoprotein Proto-oncogene Reference proteome Serine/threonine-protein kinase Transferase Zinc Zinc-finger | MEPPRGPPAN | MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCVVYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQFYHSVQDLSGGSRQHEAPSNRPLNELLTPQGPSPRTQHCDPEHFPFPAPANAPLQRIRSTSTPNVHMVSTTAPMDSNLIQLTGQSFSTDAAGSRGGSDGTPRGSPSPASVSSGRKSPHSKSPAEQRERKSLADDKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGS... | MAPK cascade negative regulation of apoptotic process phosphorylation positive regulation of peptidyl-serine phosphorylation protein modification process regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of TOR signaling cytosol; mitochondrion ATP binding MAP kinase kinase kinase activi... |
chaperone-mediated protein folding intracellular protein transmembrane transport protein import protein secretion protein targeting protein targeting to membrane protein transport protein transport by the Sec complex | cell envelope Sec protein transport complex; cytoplasm; cytoplasmic side of plasma membrane; plasma membrane | ATP binding identical protein binding preprotein binding protein-exporting ATPase activity ribonucleoprotein complex binding ribosome binding zinc ion binding | Escherichia coli | 3D-structure ATP-binding Cell inner membrane Cell membrane Cytoplasm Direct protein sequencing Membrane Metal-binding Nucleotide-binding Protein transport Reference proteome Translocase Translocation Transport Zinc | MLIKLLTKVF | MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVLENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVNKIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYSPANIMLMHHVTAALRAHALF... | chaperone-mediated protein folding intracellular protein transmembrane transport protein import protein secretion protein targeting protein targeting to membrane protein transport protein transport by the Sec complex cell envelope Sec protein transport complex; cytoplasm; cytoplasmic side of plasma membrane; plasma mem... |
chromosome condensation negative regulation of DNA recombination negative regulation of transcription by RNA polymerase II nucleosome assembly | heterochromatin; nucleosome; nucleus | chromatin DNA binding double-stranded DNA binding histone deacetylase binding nucleosomal DNA binding RNA binding structural constituent of chromatin | Homo sapiens | 3D-structure Acetylation ADP-ribosylation Chromosome Citrullination Direct protein sequencing DNA-binding Hydroxylation Intellectual disability Methylation Nucleus Phosphoprotein Reference proteome | MSETAPAAPA | MSETAPAAPAAPAPAEKTPVKKKARKSAGAAKRKASGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKAKKAGAAKAKKPAGAAKKPKKATGAATPKKSAKKTPKKAKKPAAAAGAKKAKSPKKAKAAKPKKAPKSPAKAKAVKPKAAKPKTAKPKAAKPKKAAAKKK | chromosome condensation negative regulation of DNA recombination negative regulation of transcription by RNA polymerase II nucleosome assembly heterochromatin; nucleosome; nucleus chromatin DNA binding double-stranded DNA binding histone deacetylase binding nucleosomal DNA binding RNA binding structural constituent of ... |
androgen catabolic process biomineral tissue development cell adhesion cellular response to testosterone stimulus decidualization embryo implantation negative regulation of collateral sprouting of intact axon in response to injury osteoblast differentiation positive regulation of bone resorption positive regulation of ... | cell projection; endoplasmic reticulum lumen; extracellular exosome; extracellular region; extracellular space; Golgi apparatus; perinuclear region of cytoplasm | cytokine activity extracellular matrix binding integrin binding ion binding small molecule binding | Homo sapiens | 3D-structure Alternative splicing Biomineralization Cell adhesion Cytokine Direct protein sequencing Glycoprotein Phosphoprotein Proteoglycan Reference proteome Secreted Sialic acid Signal | MRIAVICFCL | MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQNAVSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKFRISHELDSASSEVN | androgen catabolic process biomineral tissue development cell adhesion cellular response to testosterone stimulus decidualization embryo implantation negative regulation of collateral sprouting of intact axon in response to injury osteoblast differentiation positive regulation of bone resorption positive regulation of ... |
cellulose catabolic process glucomannan catabolic process xylan catabolic process | extracellular region | acetylxylan esterase activity cellulase activity cellulose binding metal ion binding | Acetivibrio thermocellus | 3D-structure Calcium Carbohydrate metabolism Cellulose degradation Direct protein sequencing Glycosidase Hydrolase Metal-binding Multifunctional enzyme Polysaccharide degradation Reference proteome Secreted Signal | MKKIVSLVCV | MKKIVSLVCVLVMLVSILGSFSVVAASPVKGFQVSGTKLLDASGNELVMRGMRDISAIDLVKEIKIGWNLGNTLDAPTETAWGNPRTTKAMIEKVREMGFNAVRVPVTWDTHIGPAPDYKIDEAWLNRVEEVVNYVLDCGMYAIINVHHDNTWIIPTYANEQRSKEKLVKVWEQIATRFKDYDDHLLFETMNEPREVGSPMEWMGGTYENRDVINRFNLAVVNTIRASGGNNDKRFILVPTNAATGLDVALNDLVIPNNDSRVIVSIHAYSPYFFAMDVNGTSYWGSDYDKASLTSELDAIYNRFVKNGRAVIIGEFGTI... | cellulose catabolic process glucomannan catabolic process xylan catabolic process extracellular region acetylxylan esterase activity cellulase activity cellulose binding metal ion binding Acetivibrio thermocellus 3D-structure Calcium Carbohydrate metabolism Cellulose degradation Direct protein sequencing Glycosidase H... |
axon development brain development cell communication by electrical coupling cellular response to magnesium ion cerebral cortex development corpus callosum development detection of mechanical stimulus involved in sensory perception of pain detection of mechanical stimulus involved in sensory perception of touch hippoca... | anchoring junction; apical plasma membrane; axon; axon initial segment; axon terminus; calyx of Held; cell junction; cell surface; cytoplasmic vesicle; cytosol; dendrite; endoplasmic reticulum; glutamatergic synapse; juxtaparanode region of axon; neuronal cell body; paranode region of axon; perikaryon; plasma membrane;... | delayed rectifier potassium channel activity disordered domain specific binding voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential voltage-gated potassium channel a... | Rattus norvegicus | 3D-structure Cell junction Cell membrane Cell projection Cytoplasmic vesicle Endoplasmic reticulum Glycoprotein Ion channel Ion transport Lipoprotein Membrane Palmitate Phosphoprotein Potassium Potassium channel Potassium transport Reference proteome RNA editing Synapse Transmembrane Transmembrane helix Transport Volta... | MTVMSGENAD | MTVMSGENADEASAAPGHPQDGSYPRQADHDDHECCERVVINISGLRFETQLKTLAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFYELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILISIVIFCLETLPELKDDKDFTGTIHRIDNTTVIYTSNIFTDPFFIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQEGNQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLK... | axon development brain development cell communication by electrical coupling cellular response to magnesium ion cerebral cortex development corpus callosum development detection of mechanical stimulus involved in sensory perception of pain detection of mechanical stimulus involved in sensory perception of touch hippoca... |
anaphase-promoting complex-dependent catabolic process cell cycle switching, mitotic to meiotic cell cycle cell division metaphase/anaphase transition of mitotic cell cycle mitotic sister chromatid segregation mitotic sister chromatid separation protein ubiquitination | anaphase-promoting complex; cell division site; cytoplasm; nucleus | DNA binding | Schizosaccharomyces pombe | Cell cycle Cell division Mitosis Nucleus Reference proteome Repeat TPR repeat Ubl conjugation pathway | MTDRLKCLIW | MTDRLKCLIWYCIDNQNYDNSIFYSERLHAIEDSNESLYLLAYSHFLNLDYNIVYDLLDRVISHVPCTYLFARTSLILGRYKQGISAVEACRSNWRSIQPNINDSISSRGHPDASCMLDVLGTMYKKAGFLKKATDCFVEAVSINPYNFSAFQNLTAIGVPLDANNVFVIPPYLTAMKGFEKSQTNATASVPEPSFLKKSKESSSSSNKFSVSESIANSYSNSSISAFTKWFDRVDASELPGSEKERHQSLKLQSQSQTSKNLLAFNDAQKADSNNRDTSLKSHFVEPRTQALRPGARLTYKLREARSSKRGESTPQSFR... | anaphase-promoting complex-dependent catabolic process cell cycle switching, mitotic to meiotic cell cycle cell division metaphase/anaphase transition of mitotic cell cycle mitotic sister chromatid segregation mitotic sister chromatid separation protein ubiquitination anaphase-promoting complex; cell division site; cyt... |
conjugation with cellular fusion MAPK cascade pheromone response MAPK cascade phosphorylation regulation of ascospore formation sporulation resulting in formation of a cellular spore | cell division site; cell tip; cytosol; nucleus | ATP binding MAP kinase kinase activity protein serine kinase activity protein serine/threonine kinase activity protein tyrosine kinase activity | Schizosaccharomyces pombe | ATP-binding Conjugation Cytoplasm Kinase Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Sporulation Transferase | MFKRRRNPKG | MFKRRRNPKGLVLNPNASVKSSDNDHKEELINNQKSFESNVEAFMEQCAHMNRRPAWISDLDNSSLEVVRHLGEGNGGAVSLVKHRNIFMARKTVYVGSDSKLQKQILRELGVLHHCRSPYIVGFYGAFQYKNNISLCMEYMDCGSLDAILREGGPIPLDILGKIINSMVKGLIYLYNVLHIIHRDLKPSNVVVNSRGEIKLCDFGVSGELVNSVAQTFVGTSTYMSPERIRGGKYTVKSDIWSLGISIIELATQELPWSFSNIDDSIGILDLLHCIVQEEPPRLPSSFPEDLRLFVDACLHKDPTLRASPQQLCAMPYF... | conjugation with cellular fusion MAPK cascade pheromone response MAPK cascade phosphorylation regulation of ascospore formation sporulation resulting in formation of a cellular spore cell division site; cell tip; cytosol; nucleus ATP binding MAP kinase kinase activity protein serine kinase activity protein serine/threo... |
protein processing involved in protein targeting to mitochondrion | mitochondrial matrix; mitochondrial processing peptidase complex; mitochondrion | metal ion binding metalloendopeptidase activity | Saccharomyces cerevisiae | 3D-structure Direct protein sequencing Hydrolase Metal-binding Metalloprotease Mitochondrion Phosphoprotein Protease Reference proteome Transit peptide Zinc | MFSRTASKFR | MFSRTASKFRNTRRLLSTISSQIPGTRTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQNRSQQGIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIERERDVIIRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITKNYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIKENTLPTTHIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNGSLA... | protein processing involved in protein targeting to mitochondrion mitochondrial matrix; mitochondrial processing peptidase complex; mitochondrion metal ion binding metalloendopeptidase activity Saccharomyces cerevisiae 3D-structure Direct protein sequencing Hydrolase Metal-binding Metalloprotease Mitochondrion Phospho... |
acetyl-CoA biosynthetic process from pyruvate glucose metabolic process tricarboxylic acid cycle | intracellular membrane-bounded organelle; mitochondrial matrix; mitochondrial pyruvate dehydrogenase complex; mitochondrion; pyruvate dehydrogenase complex | dihydrolipoyllysine-residue acetyltransferase activity identical protein binding | Homo sapiens | 3D-structure Acetylation Acyltransferase Carbohydrate metabolism Glucose metabolism Lipoyl Mitochondrion Phosphoprotein Reference proteome Repeat Transferase Transit peptide Tricarboxylic acid cycle | MWRVCARRAQ | MWRVCARRAQNVAPWAGLEARWTALQEVPGTPRVTSRSGPAPARRNSVTTGYGGVRALCGWTPSSGATPRNRLLLQLLGSPGRRYYSLPPHQKVPLPSLSPTMQAGTIARWEKKEGDKINEGDLIAEVETDKATVGFESLEECYMAKILVAEGTRDVPIGAIICITVGKPEDIEAFKNYTLDSSAAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEADISAFADYRPTEVTDLKPQVPP... | acetyl-CoA biosynthetic process from pyruvate glucose metabolic process tricarboxylic acid cycle intracellular membrane-bounded organelle; mitochondrial matrix; mitochondrial pyruvate dehydrogenase complex; mitochondrion; pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase activity identical pr... |
cholesterol efflux chylomicron remnant clearance high-density lipoprotein particle assembly intermediate-density lipoprotein particle clearance lipoprotein biosynthetic process melanosome organization negative regulation of amyloid fibril formation neuron projection development positive regulation of amyloid-beta clear... | chylomicron; extracellular exosome; extracellular matrix; extracellular space; high-density lipoprotein particle; intermediate-density lipoprotein particle; low-density lipoprotein particle; multivesicular body, internal vesicle; very-low-density lipoprotein particle | amyloid-beta binding heparan sulfate proteoglycan binding heparin binding identical protein binding lipid binding low-density lipoprotein particle receptor binding | Macaca fascicularis | Chylomicron Endosome Extracellular matrix Glycoprotein HDL Heparin-binding Lipid transport Lipid-binding Oxidation Phosphoprotein Reference proteome Repeat Secreted Signal Transport VLDL | MKVLWAALLV | MKVLWAALLVTFLAGCQAKVEQPVEPETEPELRQQAEGQSGQPWELALGRFWDYLRWVQTLSEQVQEELLSPQVTQELTTLMDETMKELKAYKSELEEQLSPVAEETRARLSKELQAAQARLGADMEDVRSRLVQYRSEVQAMLGQSTEELRARLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGVSAIRERLGPLVEQGRVRAATVGSLASQPLQERAQALGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQQISLQAEAFQARLKSWFEPLVEDMQRQWAGLVEKVQAAVGASTAPVPIDNH | cholesterol efflux chylomicron remnant clearance high-density lipoprotein particle assembly intermediate-density lipoprotein particle clearance lipoprotein biosynthetic process melanosome organization negative regulation of amyloid fibril formation neuron projection development positive regulation of amyloid-beta clear... |
cellular response to interleukin-4 cellular response to lead ion heme A biosynthetic process heme B biosynthetic process heme biosynthetic process heme O biosynthetic process negative regulation of proteasomal protein catabolic process protein homooligomerization protoporphyrinogen IX biosynthetic process response to a... | cytosol; extracellular space | identical protein binding porphobilinogen synthase activity proteasome core complex binding zinc ion binding | Mus musculus | 3D-structure Allosteric enzyme Heme biosynthesis Lyase Metal-binding Phosphoprotein Porphyrin biosynthesis Reference proteome Zinc | MHHQSVLHSG | MHHQSVLHSGYFHPLLRSWQTAASTVSASNLIYPIFVTDVPDDVQPIASLPGVARYGVNQLEEMLRPLVEAGLRCVLIFGVPSRVPKDEQGSAADSEDSPTIEAVRLLRKTFPSLLVACDVCLCPYTSHGHCGLLSENGAFLAEESRQRLAEVALAYAKAGCQVVAPSDMMDGRVEAIKAALLKHGLGNRVSVMSYSAKFASCFYGPFRDAAQSSPAFGDRRCYQLPPGARGLALRAVARDIQEGADMLMVKPGLPYLDMVREVKDKHPELPLAVYQVSGEFAMLWHGAQAGAFDLRTAVLETMTAFRRAGADIIITYFA... | cellular response to interleukin-4 cellular response to lead ion heme A biosynthetic process heme B biosynthetic process heme biosynthetic process heme O biosynthetic process negative regulation of proteasomal protein catabolic process protein homooligomerization protoporphyrinogen IX biosynthetic process response to a... |
cell surface receptor signaling pathway G protein-coupled receptor internalization rhodopsin mediated signaling pathway | cytosol; membrane; photoreceptor inner segment; photoreceptor outer segment | G protein-coupled receptor binding opsin binding phosphoprotein binding protein phosphatase inhibitor activity | Homo sapiens | Cell projection Congenital stationary night blindness Disease variant Membrane Phosphoprotein Reference proteome Retinitis pigmentosa | MAASGKTSKS | MAASGKTSKSEPNHVIFKKISRDKSVTIYLGNRDYIDHVSQVQPVDGVVLVDPDLVKGKKVYVTLTCAFRYGQEDIDVIGLTFRRDLYFSRVQVYPPVGAASTPTKLQESLLKKLGSNTYPFLLTFPDYLPCSVMLQPAPQDSGKSCGVDFEVKAFATDSTDAEEDKIPKKSSVRLLIRKVQHAPLEMGPQPRAEAAWQFFMSDKPLHLAVSLNKEIYFHGEPIPVTVTVTNNTEKTVKKIKAFVEQVANVVLYSSDYYVKPVAMEEAQEKVPPNSTLTKTLTLLPLLANNRERRGIALDGKIKHEDTNLASSTIIKEGI... | cell surface receptor signaling pathway G protein-coupled receptor internalization rhodopsin mediated signaling pathway cytosol; membrane; photoreceptor inner segment; photoreceptor outer segment G protein-coupled receptor binding opsin binding phosphoprotein binding protein phosphatase inhibitor activity Homo sapiens ... |
autophagosome assembly endoplasmic reticulum to Golgi vesicle-mediated transport Golgi organization intracellular protein transport positive regulation of glycoprotein metabolic process regulation of autophagosome assembly | endomembrane system; endoplasmic reticulum-Golgi intermediate compartment; perinuclear region of cytoplasm; phagophore assembly site membrane; synapse | G protein activity GTP binding GTPase activity | Rattus norvegicus | Acetylation Autophagy Cytoplasm GTP-binding Hydrolase Lipoprotein Membrane Methylation Nucleotide-binding Phosphoprotein Prenylation Protein transport Reference proteome Transport | MNPEYDYLFK | MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTVTSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNKSDLTTKKVVDNTTAKEFADSLGVPFLETSAKNATNVEQAFMTMAAEIKKRMGPGAASGGERPNLKIDSTPVKSASGGCC | autophagosome assembly endoplasmic reticulum to Golgi vesicle-mediated transport Golgi organization intracellular protein transport positive regulation of glycoprotein metabolic process regulation of autophagosome assembly endomembrane system; endoplasmic reticulum-Golgi intermediate compartment; perinuclear region of ... |
cell wall organization proteolysis | extracellular region | metal ion binding metallopeptidase activity | Staphylococcus simulans | 3D-structure Cell wall biogenesis/degradation Hydrolase Metal-binding Metalloprotease Protease Repeat Secreted Signal Zinc Zymogen | MKKTKNNYYT | MKKTKNNYYTRPLAIGLSTFALASIVYGGIQNETHASEKSNMDVSKKVAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKALVQNRTALRAATHEHSAQWLNNYKKGYGYGPYPLGINGGMHYGVDFFMNIGTPVKAISSGKIVEAGWSNYGGGNQIGLIEND... | cell wall organization proteolysis extracellular region metal ion binding metallopeptidase activity Staphylococcus simulans3D-structure Cell wall biogenesis/degradation Hydrolase Metal-binding Metalloprotease Protease Repeat Secreted Signal Zinc Zymogen MKKTKNNYYT MKKTKNNYYTRPLAIGLSTFALASIVYGGIQNETHASEKSNMDVSKKVAEVETSK... |
adult locomotory behavior behavioral defense response larval locomotory behavior negative regulation of heart contraction negative regulation of heart rate neuropeptide signaling pathway positive regulation of cytosolic calcium ion concentration positive regulation of neuromuscular synaptic transmission regulation of s... | extracellular space | neuropeptide receptor binding receptor ligand activity | Drosophila melanogaster | Amidation Cleavage on pair of basic residues Direct protein sequencing Neuropeptide Reference proteome Repeat Secreted Signal | MGIALMFLLA | MGIALMFLLALYQMQSAIHSEIIDTPNYAGNSLQDADSEVSPSQDNDLVDALLGNDQTERAELEFRHPISVIGIDYSKNAVVLHFQKHGRKPRYKYDPELEAKRRSVQDNFMHFGKRQAEQLPPEGSYAGSDELEGMAKRAAMDRYGRDPKQDFMRFGRDPKQDFMRFGRDPKQDFMRFGRDPKQDFMRFGRDPKQDFMRFGRTPAEDFMRFGRTPAEDFMRFGRSDNFMRFGRSPHEELRSPKQDFMRFGRPDNFMRFGRSAPQDFVRSGKMDSNFIRFGKSLKPAAPESKPVKSNQGNPGERSPVDKAMTELFKKQEL... | adult locomotory behavior behavioral defense response larval locomotory behavior negative regulation of heart contraction negative regulation of heart rate neuropeptide signaling pathway positive regulation of cytosolic calcium ion concentration positive regulation of neuromuscular synaptic transmission regulation of s... |
locomotion positive regulation of ovulation positive regulation of sarcomere organization regulation of cytoskeleton organization skeletal muscle myosin thick filament assembly | A band; myosin complex; myosin filament | cytoskeletal protein binding protein kinase binding SH3 domain binding | Caenorhabditis elegans | Alternative splicing Coiled coil Cytoplasm Direct protein sequencing Disulfide bond Motor protein Muscle protein Myosin Phosphoprotein Reference proteome Thick filament | MSLYRSPSAA | MSLYRSPSAALLKSPSQAAFGAPFGSMSVADLGSLTRLEDKIRLLQEDLESERELRNRVERERADLSVQVIALTDRLEDAEGTTDSQIESNRKREGELSKLRKLLEESQLESEDAMNVLRKKHQDSCLDYQDQIEQLQKKNAKIDRERQRVQHEVIELTATIDQLQKDKHTAEKAAERFEAQANELANKVEDLNKHVNDLAQQRQRLQAENNDLLKEVHDQKVQLDNLQHVKYTLAQQLEEARRRLEDAERERSQLQSQLHQVQLELDSVRTALDEESIARSDAEHKLNLANTEITQWKSKFDAEVALHHEEVEDLRKKM... | locomotion positive regulation of ovulation positive regulation of sarcomere organization regulation of cytoskeleton organization skeletal muscle myosin thick filament assembly A band; myosin complex; myosin filament cytoskeletal protein binding protein kinase binding SH3 domain binding Caenorhabditis elegansAlternativ... |
anatomical structure development cell differentiation detection of temperature stimulus involved in sensory perception of pain entrainment of circadian clock by photoperiod negative regulation of transcription by RNA polymerase II neuron development | chromatin; nucleoplasm; nucleus | DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific nuclear receptor activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-... | Homo sapiens | DNA-binding Metal-binding Nucleus Phosphoprotein Receptor Reference proteome Repressor Transcription Transcription regulation Zinc Zinc-finger | MAMVTGGWGG | MAMVTGGWGGPGGDTNGVDKAGGYPRAAEDDSASPPGAASDAEPGDEERPGLQVDCVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKKCFRVGMRKEAVQRGRIPHSLPGAVAASSGSPPGSALAAVASGGDLFPGQPVSELIAQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVDKLGRLQVDSAEYGCLKAIALFTPDACGLSD... | anatomical structure development cell differentiation detection of temperature stimulus involved in sensory perception of pain entrainment of circadian clock by photoperiod negative regulation of transcription by RNA polymerase II neuron development chromatin; nucleoplasm; nucleus DNA-binding transcription factor activ... |
anatomical structure development cell differentiation negative regulation of neuron projection development negative regulation of transcription by RNA polymerase II nervous system development positive regulation of transcription by RNA polymerase II signal transduction | cytosol; nucleoplasm; nucleus | DNA-binding transcription factor activity DNA-binding transcription repressor activity, RNA polymerase II-specific nuclear receptor activity retinoic acid-responsive element binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA ... | Homo sapiens | 3D-structure Activator Direct protein sequencing Disease variant DNA-binding Metal-binding Nucleus Receptor Reference proteome Repressor Transcription Transcription regulation Zinc Zinc-finger | MAMVVSSWRD | MAMVVSSWRDPQDDVAGGNPGGPNPAAQAARGGGGGAGEQQQQAGSGAPHTPQTPGQPGAPATPGTAGDKGQGPPGSGQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPNPGQYALTNGDPLNGHCYLSGYISLLLRAEPYPTSRYGSQCMQPNNIMGIENICELAARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYS... | anatomical structure development cell differentiation negative regulation of neuron projection development negative regulation of transcription by RNA polymerase II nervous system development positive regulation of transcription by RNA polymerase II signal transduction cytosol; nucleoplasm; nucleus DNA-binding transcri... |
chaperone cofactor-dependent protein refolding clathrin coat disassembly cytoplasmic translation mitochondria-associated ubiquitin-dependent protein catabolic process negative regulation of DNA-templated transcription proteasome-mediated ubiquitin-dependent protein catabolic process protein folding protein import into ... | cytoplasm; cytosol; extracellular region; fungal-type cell wall; fungal-type vacuole membrane; nucleus; plasma membrane; transcription repressor complex | ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone heat shock protein binding protein folding chaperone tRNA binding unfolded protein binding | Saccharomyces cerevisiae | 3D-structure Acetylation ATP-binding Cell wall Cytoplasm Direct protein sequencing Isopeptide bond Nucleotide-binding Phosphoprotein Reference proteome Secreted Stress response Ubl conjugation | MSKAVGIDLG | MSKAVGIDLGTTYSCVAHFANDRVDIIANDQGNRTTPSFVAFTDTERLIGDAAKNQAAMNPSNTVFDAKRLIGRNFNDPEVQADMKHFPFKLIDVDGKPQIQVEFKGETKNFTPEQISSMVLGKMKETAESYLGAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKGKEEHVLIFDLGGGTFDVSLLSIEDGIFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRALRRLRTACERAKRTLSSSAQTSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRD... | chaperone cofactor-dependent protein refolding clathrin coat disassembly cytoplasmic translation mitochondria-associated ubiquitin-dependent protein catabolic process negative regulation of DNA-templated transcription proteasome-mediated ubiquitin-dependent protein catabolic process protein folding protein import into ... |
chaperone cofactor-dependent protein refolding negative regulation of DNA-templated transcription proteasome-mediated ubiquitin-dependent protein catabolic process protein folding protein refolding response to oxygen levels SRP-dependent cotranslational protein targeting to membrane, translocation tRNA import into nucl... | cytoplasm; cytosol; extracellular region; fungal-type cell wall; fungal-type vacuole membrane; mitochondrion; nucleus; plasma membrane; transcription repressor complex | ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone heat shock protein binding protein folding chaperone tRNA binding unfolded protein binding | Saccharomyces cerevisiae | Acetylation ATP-binding Cell wall Cytoplasm Direct protein sequencing Isopeptide bond Nucleotide-binding Phosphoprotein Reference proteome Secreted Stress response Ubl conjugation | MSKAVGIDLG | MSKAVGIDLGTTYSCVAHFSNDRVDIIANDQGNRTTPSFVGFTDTERLIGDAAKNQAAMNPANTVFDAKRLIGRNFNDPEVQGDMKHFPFKLIDVDGKPQIQVEFKGETKNFTPEQISSMVLGKMKETAESYLGAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKGKEEHVLIFDLGGGTFDVSLLSIEDGIFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRALRRLRTACERAKRTLSSSAQTSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRD... | chaperone cofactor-dependent protein refolding negative regulation of DNA-templated transcription proteasome-mediated ubiquitin-dependent protein catabolic process protein folding protein refolding response to oxygen levels SRP-dependent cotranslational protein targeting to membrane, translocation tRNA import into nucl... |
activation of protein kinase B activity cell redox homeostasis cellular detoxification of hydrogen peroxide negative regulation of protein export from nucleus negative regulation of transcription by RNA polymerase II positive regulation of DNA binding positive regulation of peptidyl-cysteine S-nitrosylation positive re... | cytoplasm; cytosol; extracellular exosome; extracellular region; nucleoplasm; nucleus | protein homodimerization activity protein-disulfide reductase (NAD(P)) activity protein-disulfide reductase activity RNA binding thioredoxin-disulfide reductase (NADP) activity | Homo sapiens | 3D-structure Acetylation Activator Allergen Alternative splicing Cytoplasm Direct protein sequencing Disulfide bond Electron transport Nucleus Redox-active center Reference proteome S-nitrosylation Secreted Transcription Transcription regulation Transport Ubl conjugation | MVKQIESKTA | MVKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDDCQDVASECEVKCMPTFQFFKKGQKVGEFSGANKEKLEATINELV | activation of protein kinase B activity cell redox homeostasis cellular detoxification of hydrogen peroxide negative regulation of protein export from nucleus negative regulation of transcription by RNA polymerase II positive regulation of DNA binding positive regulation of peptidyl-cysteine S-nitrosylation positive re... |
cellular response to thyroid hormone stimulus collagen catabolic process decidualization epithelial cell differentiation neuron apoptotic process protein catabolic process proteolysis proteolysis involved in protein catabolic process thyroid hormone generation viral entry into host cell | apical plasma membrane; cell surface; collagen-containing extracellular matrix; external side of plasma membrane; extracellular region; extracellular space; lysosome; melanosome; mitochondrion; peptidase inhibitor complex; perinuclear region of cytoplasm; sarcolemma | collagen binding cysteine-type endopeptidase activity cysteine-type peptidase activity endopeptidase activity kininogen binding peptidase activity peptide binding protein self-association protein-containing complex binding proteoglycan binding | Mus musculus | Acetylation Cell membrane Disulfide bond Glycoprotein Hydrolase Lysosome Membrane Protease Reference proteome Secreted Signal Thiol protease Zymogen | MWWSLILLSC | MWWSLILLSCLLALTSAHDKPSFHPLSDDLINYINKQNTTWQAGRNFYNVDISYLKKLCGTVLGGPKLPGRVAFGEDIDLPETFDAREQWSNCPTIGQIRDQGSCGSCWAFGAVEAISDRTCIHTNGRVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWSFWTKKGLVSGGVYNSHVGCLPYTIPPCEHHVNGSRPPCTGEGDTPRCNKSCEAGYSPSYKEDKHFGYTSYSVSNSVKEIMAEIYKNGPVEGAFTVFSDFLTYKSGVYKHEAGDMMGGHAIRILGWGVENGVPYWLAANSWNLDWGDNGFFKILRGENHCG... | cellular response to thyroid hormone stimulus collagen catabolic process decidualization epithelial cell differentiation neuron apoptotic process protein catabolic process proteolysis proteolysis involved in protein catabolic process thyroid hormone generation viral entry into host cell apical plasma membrane; cell sur... |
cellular respiration mitochondrial electron transport, cytochrome c to oxygen respiratory gaseous exchange by respiratory system | mitochondrial inner membrane; mitochondrial membrane; mitochondrial respiratory chain complex IV; mitochondrion | cytochrome-c oxidase activity metal ion binding | Homo sapiens | 3D-structure Acetylation Direct protein sequencing Membrane Metal-binding Mitochondrion Mitochondrion inner membrane Reference proteome Transit peptide Zinc | MASRLLRGAG | MASRLLRGAGTLAAQALRARGPSGAAAMRSMASGGGVPTDEEQATGLEREIMLAAKKGLDPYNVLAPKGASGTREDPNLVPSISNKRIVGCICEEDNTSVVWFWLHKGEAQRCPRCGAHYKLVPQQLAH | cellular respiration mitochondrial electron transport, cytochrome c to oxygen respiratory gaseous exchange by respiratory system mitochondrial inner membrane; mitochondrial membrane; mitochondrial respiratory chain complex IV; mitochondrion cytochrome-c oxidase activity metal ion binding Homo sapiens 3D-structure Acety... |
C21-steroid hormone biosynthetic process cellular response to peptide hormone stimulus cholesterol metabolic process cortisol metabolic process glucocorticoid biosynthetic process | mitochondrial inner membrane | cholesterol monooxygenase (side-chain-cleaving) activity heme binding iron ion binding | Sus scrofa | Cholesterol metabolism Direct protein sequencing Heme Iron Lipid metabolism Membrane Metal-binding Mitochondrion Mitochondrion inner membrane Monooxygenase Oxidoreductase Reference proteome Steroid metabolism Steroidogenesis Sterol metabolism Transit peptide | MLARGLALRS | MLARGLALRSVLVKGCQPFLSAPRECPGHPRVGTGEGACISTKTPRPFSEIPSPGDNGWINLYRFWKEKGTQKIHYHHVQNFQKYGPIYREKLGNLESVYIIDPEDVALLFKFEGPNPERYNIPPWVAYHQHYQKPVGVLLKKSGAWKKDRLVLNTEVMAPEAIKNFIPLLDTVSQDFVGVLHRRIKQQGSGKFSGDIREDLFRFAFESITNVIFGERLGMLEEIVDPEAQKFIDAVYQMFHTSVPMLNLPPDLFRLFRTKTWRDHVAAWDTIFNKAEKYTQNFYWDLRRKREFNNYPGILYRLLGNDKLLSEDVKANVT... | C21-steroid hormone biosynthetic process cellular response to peptide hormone stimulus cholesterol metabolic process cortisol metabolic process glucocorticoid biosynthetic process mitochondrial inner membrane cholesterol monooxygenase (side-chain-cleaving) activity heme binding iron ion binding Sus scrofa Cholesterol m... |
cell growth mode switching, budding to filamentous endosome organization ergosterol biosynthetic process membrane raft polarization | cortical endoplasmic reticulum; endoplasmic reticulum membrane; membrane; perinuclear endoplasmic reticulum; plasma membrane | heme binding iron ion binding oxidoreductase activity sterol 14-demethylase activity | Candida albicans | 3D-structure Endoplasmic reticulum Heme Iron Lipid biosynthesis Lipid metabolism Membrane Metal-binding Monooxygenase Oxidoreductase Reference proteome Steroid biosynthesis Steroid metabolism Sterol biosynthesis Sterol metabolism Transmembrane Transmembrane helix | MAIVETVIDG | MAIVETVIDGINYFLSLSVTQQISILLGVPFVYNLVWQYLYSLRKDRAPLVFYWIPWFGSAASYGQQPYEFFESCRQKYGDVFSFMLLGKIMTVYLGPKGHEFVFNAKLSDVSAEDAYKHLTTPVFGKGVIYDCPNSRLMEQKKFAKFALTTDSFKRYVPKIREEILNYFVTDESFKLKEKTHGVANVMKTQPEITIFTASRSLFGDEMRRIFDRSFAQLYSDLDKGFTPINFVFPNLPLPHYWRRDAAQKKISATYMKEIKSRRERGDIDPNRDLIDSLLIHSTYKDGVKMTDQEIANLLIGILMGGQHTSASTSAWFL... | cell growth mode switching, budding to filamentous endosome organization ergosterol biosynthetic process membrane raft polarization cortical endoplasmic reticulum; endoplasmic reticulum membrane; membrane; perinuclear endoplasmic reticulum; plasma membrane heme binding iron ion binding oxidoreductase activity sterol 14... |
ergosterol biosynthetic process | endoplasmic reticulum; endoplasmic reticulum membrane | heme binding iron ion binding oxidoreductase activity sterol 14-demethylase activity | Saccharomyces cerevisiae | 3D-structure Endoplasmic reticulum Heme Iron Isopeptide bond Lipid biosynthesis Lipid metabolism Membrane Metal-binding Monooxygenase Oxidoreductase Phosphoprotein Reference proteome Steroid biosynthesis Steroid metabolism Sterol biosynthesis Sterol metabolism Transmembrane Transmembrane helix Ubl conjugation | MSATKSIVGE | MSATKSIVGEALEYVNIGLSHFLALPLAQRISLIIIIPFIYNIVWQLLYSLRKDRPPLVFYWIPWVGSAVVYGMKPYEFFEECQKKYGDIFSFVLLGRVMTVYLGPKGHEFVFNAKLADVSAEAAYAHLTTPVFGKGVIYDCPNSRLMEQKKFVKGALTKEAFKSYVPLIAEEVYKYFRDSKNFRLNERTTGTIDVMVTQPEMTIFTASRSLLGKEMRAKLDTDFAYLYSDLDKGFTPINFVFPNLPLEHYRKRDHAQKAISGTYMSLIKERRKNNDIQDRDLIDSLMKNSTYKDGVKMTDQEIANLLIGVLMGGQHTSA... | ergosterol biosynthetic process endoplasmic reticulum; endoplasmic reticulum membrane heme binding iron ion binding oxidoreductase activity sterol 14-demethylase activity Saccharomyces cerevisiae 3D-structure Endoplasmic reticulum Heme Iron Isopeptide bond Lipid biosynthesis Lipid metabolism Membrane Metal-binding Mon... |
intracellular protein transport negative regulation of chaperone-mediated autophagy proteolysis regulation of chaperone-mediated autophagy regulation of protein stability | azurophil granule lumen; endoplasmic reticulum; extracellular exosome; extracellular region; intracellular membrane-bounded organelle; lysosomal lumen; lysosome; membrane | carboxypeptidase activity enzyme activator activity serine-type carboxypeptidase activity | Homo sapiens | 3D-structure Alternative splicing Carboxypeptidase Direct protein sequencing Disease variant Disulfide bond Glycoprotein Hydrolase Lysosome Protease Reference proteome Signal Zymogen | MIRAAPPPLF | MIRAAPPPLFLLLLLLLLLVSWASRGEAAPDQDEIQRLPGLAKQPSFRQYSGYLKGSGSKHLHYWFVESQKDPENSPVVLWLNGGPGCSSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKFYATNDTEVAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVMQDPSMNLQGLAVGNGLSSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQEVARIVGNSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNIFTRLPLKRMWHQALLR... | intracellular protein transport negative regulation of chaperone-mediated autophagy proteolysis regulation of chaperone-mediated autophagy regulation of protein stability azurophil granule lumen; endoplasmic reticulum; extracellular exosome; extracellular region; intracellular membrane-bounded organelle; lysosomal lume... |
cellular response to lipid hydroperoxide glutathione transport | azurophil granule membrane; endoplasmic reticulum; endoplasmic reticulum membrane; membrane; mitochondrial outer membrane; mitochondrion; peroxisomal membrane; plasma membrane | glutathione peroxidase activity glutathione transferase activity | Homo sapiens | Acetylation Alternative splicing Endoplasmic reticulum Membrane Mitochondrion Mitochondrion outer membrane Reference proteome Transferase Transmembrane Transmembrane helix | MVDLTQVMDD | MVDLTQVMDDEVFMAFASYATIILSKMMLMSTATAFYRLTRKVFANPEDCVAFGKGENAKKYLRTDDRVERVRRAHLNDLENIIPFLGIGLLYSLSGPDPSTAILHFRLFVGARIYHTIAYLTPLPQPNRALSFFVGYGVTLSMAYRLLKSKLYL | cellular response to lipid hydroperoxide glutathione transport azurophil granule membrane; endoplasmic reticulum; endoplasmic reticulum membrane; membrane; mitochondrial outer membrane; mitochondrion; peroxisomal membrane; plasma membrane glutathione peroxidase activity glutathione transferase activity Homo sapiens Ace... |
cytoplasmic translation positive regulation of protein kinase activity translational elongation | cytosolic large ribosomal subunit; fungal-type vacuole | protein kinase activator activity ribonucleoprotein complex binding structural constituent of ribosome | Saccharomyces cerevisiae | Acetylation Cytoplasm Direct protein sequencing Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein | MSDSIISFAA | MSDSIISFAAFILADAGLEITSDNLLTITKAAGANVDNVWADVYAKALEGKDLKEILSGFHNAGPVAGAGAASGAAAAGGDAAAEEEKEEEAAEESDDDMGFGLFD | cytoplasmic translation positive regulation of protein kinase activity translational elongation cytosolic large ribosomal subunit; fungal-type vacuole protein kinase activator activity ribonucleoprotein complex binding structural constituent of ribosome Saccharomyces cerevisiae Acetylation Cytoplasm Direct protein seq... |
actomyosin structure organization developmental process ectoderm and mesoderm interaction gastrulation gastrulation involving germ band extension heart development Malpighian tubule morphogenesis mesoderm development mesodermal cell fate commitment mesodermal cell fate specification muscle cell development positive reg... | cytoplasm; nucleus | DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific protein heterodimerization activity protein homodimerization activity RNA polymerase II transcription regulatory region sequence-specific DNA binding | Drosophila melanogaster | Developmental protein Differentiation DNA-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MMSARSVSPK | MMSARSVSPKVLLDISYKPTLPNIMELQNNVIKLIQVEQQAYMQSGYQLQHQQQHLHSHQHHQQHHQQQHAQYAPLPSEYAAYGITELEDTDYNIPSNEVLSTSSNQSAQSTSLELNNNNTSSNTNSSGNNPSGFDGQASSGSSWNEHGKRARSSGDYDCQTGGSLVMQPEHKKLIHQQQQQQQQHQQQIYVDYLPTTVDEVASAQSCPGVQSTCTSPQSHFDFPDEELPEHKAQVFLPLYNNQQQQSQQLQQQQPHQQSHAQMHFQNAYRQSFEGYEPANSLNGSAYSSSDRDDMEYARHNALSSVSDLNGGVMSPACL... | actomyosin structure organization developmental process ectoderm and mesoderm interaction gastrulation gastrulation involving germ band extension heart development Malpighian tubule morphogenesis mesoderm development mesodermal cell fate commitment mesodermal cell fate specification muscle cell development positive reg... |
anterior/posterior pattern specification embryonic skeletal system morphogenesis positive regulation of transcription by RNA polymerase II stem cell differentiation | cell junction; nucleoplasm | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific double-st... | Mus musculus | Developmental protein DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation | MAMSSYMVNS | MAMSSYMVNSKYVDPKFPPCEEYLQGGYLGEQGADYYGSGAQGADFQPSGLYPRPDFGEQPFGGGGPGPGSALPARGHGQEPSGPGSHYGAPGERCPAPPPAPLPGARACSQPTGPKQPPPGTALKQPAVVYPWMKKVHVNSVNPNYTGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSSSSSSCSSSAAPGQHLQPMAKDHHTDLTTL | anterior/posterior pattern specification embryonic skeletal system morphogenesis positive regulation of transcription by RNA polymerase II stem cell differentiation cell junction; nucleoplasm DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymera... |
epoxygenase P450 pathway estrogen metabolic process icosanoid biosynthetic process lipid hydroxylation long-chain fatty acid biosynthetic process omega-hydroxylase P450 pathway organic acid metabolic process oxidative demethylation retinoic acid metabolic process retinol metabolic process steroid metabolic process xeno... | cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; plasma membrane | arachidonic acid epoxygenase activity aromatase activity caffeine oxidase activity estrogen 16-alpha-hydroxylase activity heme binding iron ion binding monooxygenase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one dono... | Homo sapiens | 3D-structure Alternative splicing Direct protein sequencing Endoplasmic reticulum Heme Iron Lipid metabolism Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Phosphoprotein Reference proteome Steroid metabolism | MEPFVVLVLC | MEPFVVLVLCLSFMLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVT... | epoxygenase P450 pathway estrogen metabolic process icosanoid biosynthetic process lipid hydroxylation long-chain fatty acid biosynthetic process omega-hydroxylase P450 pathway organic acid metabolic process oxidative demethylation retinoic acid metabolic process retinol metabolic process steroid metabolic process xeno... |
arachidonic acid metabolic process response to organic cyclic compound response to organic substance response to xenobiotic stimulus xenobiotic catabolic process xenobiotic metabolic process | cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; mitochondrion | aromatase activity heme binding iron ion binding monooxygenase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | Rattus norvegicus | Endoplasmic reticulum Heme Iron Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Reference proteome | MELLNGTGLW | MELLNGTGLWSMAIFTVIFILLVDLMHRRHRWTSRYPPGPVPWPVLGNLLQVDLSNMPYSLYKLQHRYGDVFSLQKGWKPMVIVNRLKAVQEVLVTHGEDTADRPPVPIFKCLGVKPRSQGVILASYGPEWREQRRFSVSTLRTFGMGKKSLEEWVTKEAGHLCDAFTAQAGQSINPKAMLNKALCNVIASLIFARRFEYEDPYLIRMVKLVEESLTEVSGFIPEVLNTFPALLRIPGLADKVFQGQKTFMALLDNLLAENRTTWDPAQPPRNLTDAFLAEVEKAKGNPESSFNDENLRMVVVDLFTAGMVTTATTLTWA... | arachidonic acid metabolic process response to organic cyclic compound response to organic substance response to xenobiotic stimulus xenobiotic catabolic process xenobiotic metabolic process cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; mitochondrion aromatase activity heme bindin... |
arachidonic acid metabolic process female pregnancy response to xenobiotic stimulus xenobiotic metabolic process | cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle | aromatase activity heme binding iron ion binding monooxygenase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | Rattus norvegicus | Endoplasmic reticulum Heme Iron Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Phosphoprotein Reference proteome | MGLLIGDDLW | MGLLIGDDLWAVVIFTAIFLLLVDLVHRHKFWTAHYPPGPVPLPGLGNLLQVDFENMPYSLYKLRSRYGDVFSLQIAWKPVVVINGLKAVRELLVTYGEDTADRPLLPIYNHLGYGNKSKGVVLAPYGPEWREQRRFSVSTLRDFGVGKKSLEQWVTEEAGHLCDTFAKEAEHPFNPSILLSKAVSNVIASLVYARRFEYEDPFFNRMLKTLKESFGEDTGFMAEVLNAIPILLQIPGLPGKVFPKLNSFIALVDKMLIEHKKSWDPAQPPRDMTDAFLAEMQKAKGNPESSFNDENLRLVVIDLFMAGMVTTSTTLSWA... | arachidonic acid metabolic process female pregnancy response to xenobiotic stimulus xenobiotic metabolic process cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle aromatase activity heme binding iron ion binding monooxygenase activity oxidoreductase activity, acting on paired donors, w... |
alkaloid catabolic process alkaloid metabolic process arachidonic acid metabolic process cholesterol metabolic process coumarin metabolic process estrogen metabolic process heterocycle metabolic process isoquinoline alkaloid metabolic process long-chain fatty acid biosynthetic process monoterpenoid metabolic process ne... | cytoplasm; endoplasmic reticulum; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; mitochondrion | anandamide 11,12 epoxidase activity anandamide 14,15 epoxidase activity anandamide 8,9 epoxidase activity heme binding iron ion binding monooxygenase activity oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as ... | Homo sapiens | 3D-structure Alternative splicing Cholesterol metabolism Endoplasmic reticulum Fatty acid metabolism Heme Iron Lipid metabolism Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Reference proteome Steroid metabolism Sterol metabolism | MGLEALVPLA | MGLEALVPLAVIVAIFLLLVDLMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLL... | alkaloid catabolic process alkaloid metabolic process arachidonic acid metabolic process cholesterol metabolic process coumarin metabolic process estrogen metabolic process heterocycle metabolic process isoquinoline alkaloid metabolic process long-chain fatty acid biosynthetic process monoterpenoid metabolic process ne... |
cell redox homeostasis cellular detoxification of hydrogen peroxide negative regulation of protein export from nucleus negative regulation of transcription by RNA polymerase II positive regulation of DNA binding positive regulation of peptidyl-cysteine S-nitrosylation positive regulation of peptidyl-serine phosphorylat... | axon; cytoplasm; cytosol; dendrite; extracellular region; mitochondrion; neuronal cell body; nucleoplasm; nucleus | enzyme binding protein homodimerization activity protein-disulfide reductase (NAD(P)) activity protein-disulfide reductase activity | Mus musculus | Acetylation Activator Cytoplasm Disulfide bond Electron transport Nucleus Redox-active center Reference proteome S-nitrosylation Secreted Transcription Transcription regulation Transport | MVKLIESKEA | MVKLIESKEAFQEALAAAGDKLVVVDFSATWCGPCKMIKPFFHSLCDKYSNVVFLEVDVDDCQDVAADCEVKCMPTFQFYKKGQKVGEFSGANKEKLEASITEYA | cell redox homeostasis cellular detoxification of hydrogen peroxide negative regulation of protein export from nucleus negative regulation of transcription by RNA polymerase II positive regulation of DNA binding positive regulation of peptidyl-cysteine S-nitrosylation positive regulation of peptidyl-serine phosphorylat... |
adenylate cyclase-activating G protein-coupled receptor signaling pathway cardiac muscle cell proliferation cellular response to glucagon stimulus intracellular signal transduction mesoderm formation negative regulation of activated T cell proliferation negative regulation of cAMP-dependent protein kinase activity nega... | cAMP-dependent protein kinase complex; centrosome; ciliary base; cytoplasm; cytosol; glutamatergic synapse; membrane; multivesicular body; neuromuscular junction; nucleotide-activated protein kinase complex; plasma membrane raft; protein-containing complex; sperm connecting piece | cAMP binding cAMP-dependent protein kinase inhibitor activity cAMP-dependent protein kinase regulator activity protein domain specific binding protein kinase A catalytic subunit binding ubiquitin protein ligase binding | Homo sapiens | 3D-structure Acetylation Alternative splicing cAMP cAMP-binding Cell membrane Cushing syndrome Direct protein sequencing Disease variant Disulfide bond Membrane Nucleotide-binding Phosphoprotein Reference proteome Repeat | MESGSTAASE | MESGSTAASEEARSLRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFERLEKEEAKQIQNLQKAGTRTDSREDEISPPPPNPVVKGRRRRGAISAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFSVSFIAGETVIQQGDEGDNFYVIDQGETDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGP... | adenylate cyclase-activating G protein-coupled receptor signaling pathway cardiac muscle cell proliferation cellular response to glucagon stimulus intracellular signal transduction mesoderm formation negative regulation of activated T cell proliferation negative regulation of cAMP-dependent protein kinase activity nega... |
blood coagulation cellular response to steroid hormone stimulus negative regulation of blood coagulation | caveola; cell surface; endoplasmic reticulum; extracellular region; extracellular space; plasma membrane; side of membrane | endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity | Homo sapiens | 3D-structure Alternative splicing Blood coagulation Direct protein sequencing Disulfide bond Endoplasmic reticulum Glycoprotein GPI-anchor Hemostasis Lipoprotein Membrane Microsome Protease inhibitor Reference proteome Repeat Secreted Serine protease inhibitor Signal | MIYTMKKVHA | MIYTMKKVHALWASVCLLLNLAPAPLNADSEEDEEHTIITDTELPPLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRIIKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGPNGFQVDNYGTQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKKGFIQRISKGGLIKTKRKRKKQRVKIAYEEIFVKNM | blood coagulation cellular response to steroid hormone stimulus negative regulation of blood coagulation caveola; cell surface; endoplasmic reticulum; extracellular region; extracellular space; plasma membrane; side of membrane endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity Homo sapiens 3... |
glutathione metabolic process response to bacterium response to stilbenoid xenobiotic metabolic process | cytosol | dinitrosyl-iron complex binding fatty acid binding glutathione binding glutathione peroxidase activity glutathione transferase activity protein homodimerization activity steroid delta-isomerase activity | Mus musculus | 3D-structure Acetylation Reference proteome Transferase | MAGKPVLHYF | MAGKPVLHYFNARGRMECIRWLLAAAGVEFEEKFIQSPEDLEKLKKDGNLMFDQVPMVEIDGMKLVQTRAILNYIATKYDLYGKDMKERALIDMYTEGILDLTEMIGQLVLCPPDQREAKTALAKDRTKNRYLPAFEKVLKSHGQDYLVGNRLTRVDVHLLELLLYVEELDASLLTPFPLLKAFKSRISSLPNVKKFLHPGSQRKPPLDAKQIEEARKVFKF | glutathione metabolic process response to bacterium response to stilbenoid xenobiotic metabolic process cytosol dinitrosyl-iron complex binding fatty acid binding glutathione binding glutathione peroxidase activity glutathione transferase activity protein homodimerization activity steroid delta-isomerase activity Mus m... |
cellular response to xenobiotic stimulus glutathione derivative biosynthetic process glutathione metabolic process hepoxilin biosynthetic process prostaglandin metabolic process xenobiotic catabolic process | cytoplasm; cytosol; extracellular region; intercellular bridge; myelin sheath; protein-containing complex | enzyme binding glutathione binding glutathione transferase activity identical protein binding nickel cation binding protein homodimerization activity protein kinase binding steroid binding | Mus musculus | Cytoplasm Direct protein sequencing Lipid metabolism Phosphoprotein Reference proteome Transferase | MPMILGYWNV | MPMILGYWNVRGLTHPIRMLLEYTDSSYDEKRYTMGDAPDFDRSQWLNEKFKLGLDFPNLPYLIDGSHKITQSNAILRYLARKHHLDGETEEERIRADIVENQVMDTRMQLIMLCYNPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYRMFEPKCLDAFPNLRDFLARFEGLKKISAYMKSSRYIATPIFSKMAHWSNK | cellular response to xenobiotic stimulus glutathione derivative biosynthetic process glutathione metabolic process hepoxilin biosynthetic process prostaglandin metabolic process xenobiotic catabolic process cytoplasm; cytosol; extracellular region; intercellular bridge; myelin sheath; protein-containing complex enzyme ... |
DNA damage response heterochromatin boundary formation mitotic sister chromatid biorientation | chromosome, subtelomeric region; heterochromatin; mating-type region heterochromatin; nucleosome; nucleus; pericentric heterochromatin | chromatin-protein adaptor activity DNA binding protein heterodimerization activity structural constituent of chromatin | Schizosaccharomyces pombe | Acetylation Chromosome DNA-binding Methylation Nucleosome core Nucleus Phosphoprotein Reference proteome | MARTKQTARK | MARTKQTARKSTGGKAPRKQLASKAARKAAPATGGVKKPHRYRPPTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAIGALQEAVEAYLVSLFEDTNLCAIHGKRVTIQPKDMQLARRLRGERS | DNA damage response heterochromatin boundary formation mitotic sister chromatid biorientation chromosome, subtelomeric region; heterochromatin; mating-type region heterochromatin; nucleosome; nucleus; pericentric heterochromatin chromatin-protein adaptor activity DNA binding protein heterodimerization activity structur... |
microtubule cytoskeleton organization microtubule depolymerization microtubule-based process mitotic cell cycle mitotic sister chromatid segregation mitotic spindle disassembly nuclear migration along microtubule response to antibiotic | cytoplasm; cytoplasmic microtubule; microtubule; spindle microtubule; tubulin complex | GTP binding GTPase activity metal ion binding structural constituent of cytoskeleton | Emericella nidulans | Antibiotic resistance Cytoplasm Cytoskeleton GTP-binding Magnesium Metal-binding Microtubule Nucleotide-binding Reference proteome | MREIVHLQTG | MREIVHLQTGQCGNQIGAAFWQTISGEHGLDGSGVYNGTSDLQLERMNVYFNEASGNKYVPRAVLVDLEPGTMDAVRAGPFGELFRPDNFVFGQSGAGNNWAKGHYTEGAELVDNVVDVVRREAEGCDCLQGFQITHSLGGGTGAGMGTLLISKIREEFPDRMMATFSVVPSPKVSDTVVEPYNATLSVHQLVEHSDETFCIDNEALYDICMRTLKLSNPSYGDLNHLVSAVMSGVTTCLRFPGQLNSDLRKLAVNMVPFPRLHFFMVGFAPLTSRGAYSFRAVSVPELTQQMFDPKNMMAASDFRNGRYLTCSAIFRGK... | microtubule cytoskeleton organization microtubule depolymerization microtubule-based process mitotic cell cycle mitotic sister chromatid segregation mitotic spindle disassembly nuclear migration along microtubule response to antibiotic cytoplasm; cytoplasmic microtubule; microtubule; spindle microtubule; tubulin comple... |
methionine metabolic process one-carbon metabolic process S-adenosylmethionine biosynthetic process | cytoplasm; cytoplasmic stress granule; cytosol | ATP binding metal ion binding methionine adenosyltransferase activity | Saccharomyces cerevisiae | ATP-binding Direct protein sequencing Magnesium Metal-binding Nucleotide-binding One-carbon metabolism Potassium Reference proteome Transferase | MAGTFLFTSE | MAGTFLFTSESVGEGHPDKICDQVSDAILDACLAEDPHSKVACETAAKTGMIMVFGEITTKAQLDYQKIVRDTIKKIGYDDSAKGFDYKTCNVLVAIEQQSPDIAQGVHEEKDLEDIGAGDQGIMFGYATDETPEGLPLTILLAHKLNMAMADARRDGSLAWLRPDTKTQVTVEYKDDHGRWVPQRIDTVVVSAQHADEITTEDLRAQLKSEIIEKVIPRDMLDENTKYFIQPSGRFVIGGPQGDAGLTGRKIIVDAYGGASSVGGGAFSGKDYSKVDRSAAYAARWVAKSLVAAGLCKRVQVQFSYAIGIAEPLSLHVD... | methionine metabolic process one-carbon metabolic process S-adenosylmethionine biosynthetic process cytoplasm; cytoplasmic stress granule; cytosol ATP binding metal ion binding methionine adenosyltransferase activity Saccharomyces cerevisiae ATP-binding Direct protein sequencing Magnesium Metal-binding Nucleotide-bind... |
cytoplasmic translation | cytosol; cytosolic large ribosomal subunit; nucleus | RNA binding structural constituent of ribosome | Saccharomyces cerevisiae | 3D-structure Acetylation Cytoplasm Direct protein sequencing Methylation Nucleus Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding | MSRPQVTVHS | MSRPQVTVHSLTGEATANALPLPAVFSAPIRPDIVHTVFTSVNKNKRQAYAVSEKAGHQTSAESWGTGRAVARIPRVGGGGTGRSGQGAFGNMCRGGRMFAPTKTWRKWNVKVNHNEKRYATASAIAATAVASLVLARGHRVEKIPEIPLVVSTDLESIQKTKEAVAALKAVGAHSDLLKVLKSKKLRAGKGKYRNRRWTQRRGPLVVYAEDNGIVKALRNVPGVETANVASLNLLQLAPGAHLGRFVIWTEAAFTKLDQVWGSETVASSKVGYTLPSHIISTSDVTRIINSSEIQSAIRPAGQATQKRTHVLKKNPLKN... | cytoplasmic translation cytosol; cytosolic large ribosomal subunit; nucleus RNA binding structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Acetylation Cytoplasm Direct protein sequencing Methylation Nucleus Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding MSRPQVTVHS MSRPQVTVHSLT... |
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