Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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actin filament fragmentation actin filament organization actin filament severing cytoskeleton organization establishment of spindle localization mitotic cytokinesis positive regulation of embryonic development regulation of cell morphogenesis | actin cytoskeleton; cytoplasm; growth cone; lamellipodium; lamellipodium membrane; nuclear matrix; ruffle membrane | actin filament binding | Sus scrofa | Acetylation Actin-binding Cell membrane Cell projection Cytoplasm Cytoskeleton Direct protein sequencing Isopeptide bond Membrane Nucleus Phosphoprotein Reference proteome Ubl conjugation | MASGVAVSDG | MASGVAVSDGVIKVFNDMKVRKSSTPEEVKKRKKAVLFCLSEDKKNIILEEGKEILVGDVGQTVDDPYATFVKMLPDKDCRYALYDATYETKESKKEDLVFIFWAPECAPLKSKMIYASSKDAIKKKLTGIKHELQANCYEEVKDRCTLAEKLGGSAVISLEGKPL | actin filament fragmentation actin filament organization actin filament severing cytoskeleton organization establishment of spindle localization mitotic cytokinesis positive regulation of embryonic development regulation of cell morphogenesis actin cytoskeleton; cytoplasm; growth cone; lamellipodium; lamellipodium memb... |
cell differentiation negative regulation of activin receptor signaling pathway regulation of BMP signaling pathway | extracellular space | activin binding | Sus scrofa | Alternative splicing Direct protein sequencing Disulfide bond Glycoprotein Reference proteome Repeat Secreted Signal | MVRPKHQPGG | MVRPKHQPGGLCLLLLLLCQFMEDRSAQAGNCWLRQAKNGRCQVLYKTELSKEECCSTGRLSTSWTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAPDCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGKCKKTCRDVFCPGSSTCVVDQTNNAYCVTCNRICPEPTSSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCIKAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELCPESKSEEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSCNSIS... | cell differentiation negative regulation of activin receptor signaling pathway regulation of BMP signaling pathway extracellular space activin binding Sus scrofa Alternative splicing Direct protein sequencing Disulfide bond Glycoprotein Reference proteome Repeat Secreted Signal MVRPKHQPGG MVRPKHQPGGLCLLLLLLCQFMEDRSAQAG... |
axon guidance calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules cell adhesion extracellular matrix organization homophilic cell adhesion via plasma membrane adhesion molecules neuron recognition | extracellular matrix; extracellular space; plasma membrane; side of membrane | cell adhesion molecule binding | Drosophila melanogaster | 3D-structure Alternative splicing Cell adhesion Cell membrane Glycoprotein GPI-anchor Lipoprotein Membrane Reference proteome Repeat Signal | MLNAAALLLA | MLNAAALLLALLCAANAAAAADLADKLRDDSELSQFYSLLESNQIANSTLSLRSCTIFVPTNEAFQRYKSKTAHVLYHITTEAYTQKRLPNTVSSDMAGNPPLYITKNSNGDIFVNNARIIPSLSVETNSDGKRQIMHIIDEVLEPLTVKAGHSDTPNNPNALKFLKNAEEFNVDNIGVRTYRSQVTMAKKESVYDAAGQHTFLVPVDEGFKLSARSSLVDGKVIDGHVIPNTVIFTAAAQHDDPKASAAFEDLLKVTVSFFKQKNGKMYVKSNTIVGDAKHRVGVVLAEIVKANIPVSNGVVHLIHRPLMIIDTTVTQF... | axon guidance calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules cell adhesion extracellular matrix organization homophilic cell adhesion via plasma membrane adhesion molecules neuron recognition extracellular matrix; extracellular space; plasma membrane; side of membrane cell adhesion m... |
cAMP-mediated signaling feeding behavior negative regulation of cell population proliferation negative regulation of lymphocyte proliferation nervous system development neuropeptide signaling pathway parental behavior positive regulation of apoptotic process positive regulation of cortisol secretion positive regulation... | extracellular space; neuronal cell body; secretory granule | G protein-coupled receptor binding galanin receptor activity galanin receptor binding neuropeptide hormone activity type 1 galanin receptor binding type 2 galanin receptor binding type 3 galanin receptor binding | Rattus norvegicus | Amidation Cleavage on pair of basic residues Hormone Neuropeptide Phosphoprotein Reference proteome Secreted Signal | MARGSVILLA | MARGSVILLAWLLLVATLSATLGLGMPTKEKRGWTLNSAGYLLGPHAIDNHRSFSDKHGLTGKRELPLEVEEGRLGSVAVPLPESNIVRTIMEFLSFLHLKEAGALDSLPGIPLATSSEDLEQS | cAMP-mediated signaling feeding behavior negative regulation of cell population proliferation negative regulation of lymphocyte proliferation nervous system development neuropeptide signaling pathway parental behavior positive regulation of apoptotic process positive regulation of cortisol secretion positive regulation... |
angiogenesis G protein-coupled receptor signaling pathway labyrinthine layer blood vessel development lipid catabolic process phosphatidylinositol metabolic process phosphatidylinositol-mediated signaling phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of inositol trisphospha... | cytoplasm; cytosol; mitochondrial membrane | calcium ion binding calcium-dependent phospholipid binding enzyme binding GTPase activating protein binding inositol 1,4,5 trisphosphate binding phosphatidic acid binding phosphatidylinositol phosphate binding phosphatidylinositol phospholipase C activity phosphatidylinositol-4,5-bisphosphate binding phospholipase C ac... | Rattus norvegicus | 3D-structure Calcium Direct protein sequencing Glycoprotein Hydrolase Lipid degradation Lipid metabolism Metal-binding Phosphoprotein Reference proteome Repeat Transducer | MDSGRDFLTL | MDSGRDFLTLHGLQDDPDLQALLKGSQLLKVKSSSWRRERFYKLQEDCKTIWQESRKVMRSPESQLFSIEDIQEVRMGHRTEGLEKFARDIPEDRCFSIVFKDQRNTLDLIAPSPADAQHWVQGLRKIIHHSGSMDQRQKLQHWIHSCLRKADKNKDNKMNFKELKDFLKELNIQVDDGYARKIFRECDHSQTDSLEDEEIETFYKMLTQRAEIDRAFEEAAGSAETLSVERLVTFLQHQQREEEAGPALALSLIERYEPSETAKAQRQMTKDGFLMYLLSADGNAFSLAHRRVYQDMDQPLSHYLVSSSHNTYLLEDQL... | angiogenesis G protein-coupled receptor signaling pathway labyrinthine layer blood vessel development lipid catabolic process phosphatidylinositol metabolic process phosphatidylinositol-mediated signaling phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of inositol trisphospha... |
dephosphorylation | extracellular region; plasma membrane; side of membrane | alkaline phosphatase activity metal ion binding | Homo sapiens | Calcium Cell membrane Disulfide bond Glycoprotein GPI-anchor Hydrolase Lipoprotein Magnesium Membrane Metal-binding Reference proteome Signal Zinc | MQGPWVLLLL | MQGPWVLLLLGLRLQLSLGIIPVEEENPDFWNRQAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKKDKLGPETFLAMDRFPYVALSKTYSVDKHVPDSGATATAYLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGAYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAKHQGARYVWNRTELLQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALLLLSR... | dephosphorylation extracellular region; plasma membrane; side of membrane alkaline phosphatase activity metal ion binding Homo sapiens Calcium Cell membrane Disulfide bond Glycoprotein GPI-anchor Hydrolase Lipoprotein Magnesium Membrane Metal-binding Reference proteome Signal Zinc MQGPWVLLLL MQGPWVLLLLGLRLQLSLGIIPVEEEN... |
DNA-templated transcription erythrocyte differentiation positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II transcription elongation by RNA polymerase II | nucleolus; nucleoplasm; nucleus; transcription factor TFIID complex | DNA binding zinc ion binding | Mus musculus | Acetylation Alternative splicing Direct protein sequencing DNA-binding Isopeptide bond Metal-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | MEDEVVRIAK | MEDEVVRIAKKMDKMVQKKNAAGALDLLKELKNIPMTLELLQSTRIGMSVNALRKQSTDEEVTSLAKSLIKSWKKLLDGPSTDKDPEEKKKEPAISSQNSPEAREESSSSSNVSSRKDETNARDTYVSSFPRAPSTSDSVRLKCREMLAAALRTGDDYVAIGADEEELGSQIEEAIYQEIRNTDMKYKNRVRSRISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKFC | DNA-templated transcription erythrocyte differentiation positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II transcription elongation by RNA polymerase II nucleolus; nucleoplasm; nucleus; transcription factor TFIID complex DNA binding zinc ion binding Mus musculus... |
angiogenesis ATP biosynthetic process cellular response to interleukin-7 cellular response to peptide cold acclimation lipid metabolic process liver development negative regulation of cell adhesion involved in substrate-bound cell migration positive regulation of blood vessel endothelial cell migration proton motive fo... | cell surface; membrane; membrane raft; mitochondrial inner membrane; mitochondrial membrane; mitochondrial nucleoid; mitochondrial proton-transporting ATP synthase complex; mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1); mitochondrion; plasma membrane; proton-transporting ATP synthase com... | ADP binding angiostatin binding ATP binding ATP hydrolysis activity calcium ion binding lipoprotein particle receptor activity MHC class I protein binding proton-transporting ATP synthase activity, rotational mechanism proton-transporting ATPase activity, rotational mechanism | Rattus norvegicus | 3D-structure Acetylation ATP synthesis ATP-binding CF(1) Direct protein sequencing Glycoprotein Hydrogen ion transport Ion transport Membrane Mitochondrion Mitochondrion inner membrane Nucleotide-binding Phosphoprotein Reference proteome Transit peptide Translocase Transport | MLSLVGRVAS | MLSLVGRVASASASGALRGLNPLAALPQAHLLLRTAPAGVHPARDYAAQSSAAPKAGTATGQIVAVIGAVVDVQFDEGLPPILNALEVQGRESRLVLEVAQHLGESTVRTIAMDGTEGLVRGQKVLDSGAPIKIPVGPETLGRIMNVIGEPIDERGPIKTKQFAPIHAEAPEFIEMSVEQEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVINLKDATSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSA... | angiogenesis ATP biosynthetic process cellular response to interleukin-7 cellular response to peptide cold acclimation lipid metabolic process liver development negative regulation of cell adhesion involved in substrate-bound cell migration positive regulation of blood vessel endothelial cell migration proton motive fo... |
antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to lipopolysaccharide chemokine-mediated signaling pathway inflammatory response neutrophil chemotaxis | extracellular space | chemokine activity CXCR chemokine receptor binding heparin binding | Homo sapiens | 3D-structure Cytokine Direct protein sequencing Disulfide bond Glycoprotein Heparin-binding Proteoglycan Reference proteome Secreted Signal | MSSAARSRLT | MSSAARSRLTRATRQEMLFLALLLLPVVVAFARAEAEEDGDLQCLCVKTTSQVRPRHITSLEVIKAGPHCPTAQLIATLKNGRKICLDLQALLYKKIIKEHLES | antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to lipopolysaccharide chemokine-mediated signaling pathway inflammatory response neutrophil chemotaxis extracellular space chemokine activity CXCR chemokine receptor binding heparin binding Homo sapiens 3D-structure Cytokine Direc... |
fatty acid primary amide biosynthetic process peptide amidation | extracellular region; secretory granule membrane; transport vesicle membrane | calcium ion binding copper ion binding L-ascorbic acid binding peptidylamidoglycolate lyase activity peptidylglycine monooxygenase activity zinc ion binding | Bos taurus | Calcium Cleavage on pair of basic residues Copper Cytoplasmic vesicle Direct protein sequencing Disulfide bond Glycoprotein Lipid metabolism Lyase Membrane Metal-binding Monooxygenase Multifunctional enzyme Oxidoreductase Phosphoprotein Reference proteome Repeat Signal Transmembrane Transmembrane helix Vitamin C Zinc | MAGFRSLLVL | MAGFRSLLVLLLVFPSGCVGFRSPLSVFKRFKETTRSFSNECLGTTRPVIPIDSSDFALDIRMPGVTPKQSDTYFCMSVRLPMDEEAFVIDFKPRASMDTVHHMLLFGCNMPASTGNYWFCDEGTCTDKANILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNHKDCSGVSLHLTRLPQPLIAGMYLMMSVDTVIPPGGKVVNSDISCHYKKYPMHVFAYRVHTHHLGKVVSGYRVRNGQWTLIGRQSPQLPQAFYPVEHPVDVSFGDILAARCVFTGEGRTEVTHIGGTSSDEMCNLYIMYYMEA... | fatty acid primary amide biosynthetic process peptide amidation extracellular region; secretory granule membrane; transport vesicle membrane calcium ion binding copper ion binding L-ascorbic acid binding peptidylamidoglycolate lyase activity peptidylglycine monooxygenase activity zinc ion binding Bos taurus Calcium Cle... |
actin filament bundle assembly actin filament fragmentation actin filament severing actin polymerization or depolymerization barbed-end actin filament capping | actin cytoskeleton; cytoplasm; phagocytic vesicle | actin filament binding actin filament severing activity actin monomer binding calcium ion binding calcium-dependent protein binding phosphatidylinositol-4,5-bisphosphate binding | Dictyostelium discoideum | 3D-structure Actin capping Actin-binding Calcium Direct protein sequencing Reference proteome Repeat | MIKNRKLDIT | MIKNRKLDITSTNVAGIGTDLDKKCRLDAASTEAQWKGVGQAPGLKIWRIENFKVVPVPESSYGKFYDGDSYIILHTFKEGNSLKHDIHFFLGTFTTQDEAGTAAYKTVELDDFLGGAPIQYRQCQSYESPSFLSLFPKYFILSGGVESGFNHVKPTEYKPRLLHISGDKNAKVAEVPLATSSLNSGDCFLLDAGLTIYQFNGSKSSPQEKNKAAEVARAIDAERKGLPKVEVFCETDSDIPAEFWKLLGGKGAIAAKHETAPTKSEKVLYKLSDASGSLKFSEVSRGKINKSSLKSEDVFIIDLGNEIYTWIGSKSSPN... | actin filament bundle assembly actin filament fragmentation actin filament severing actin polymerization or depolymerization barbed-end actin filament capping actin cytoskeleton; cytoplasm; phagocytic vesicle actin filament binding actin filament severing activity actin monomer binding calcium ion binding calcium-depen... |
epithelial cell migration, open tracheal system negative regulation of DNA-templated transcription regulation of DNA-templated transcription regulation of mitotic nuclear division regulation of transcription by RNA polymerase II trunk segmentation zygotic determination of anterior/posterior axis, embryo | nucleus | DNA-binding transcription factor activity DNA-binding transcription factor binding DNA-binding transcription repressor activity, RNA polymerase II-specific estrogen response element binding nuclear receptor activity zinc ion binding | Drosophila melanogaster | Developmental protein DNA-binding Metal-binding Nucleus Receptor Reference proteome Repressor Transcription Transcription regulation Zinc Zinc-finger | MNQTCKVCGE | MNQTCKVCGEPAAGFHFGAFTCEGCKSFFGRSYNNISTISECKNEGKCIIDKKNRTTCKACRLRKCYNVGMSKGGSRYGRRSNWFKIHCLLQEHEQAAAAAGKAPPLAGGVSVGGAPSASSPVGSPHTPGFGDMAAHLHHHHQQQQQQQVPRHPHMPLLGYPSYLSDPSAALPFFSMMGGVPHQSPFQLPPHLLFPGYHASAAAAAASAADAAYRQEMYKHRQSVDSVESQNRFSPASQPPVVQPTSSARQSPIDVCLEEDVHSVHSHQSSASLLHPIAIRATPTTPTSSSPLSFAAKMQSLSPVSVCSIGGETTSVVPV... | epithelial cell migration, open tracheal system negative regulation of DNA-templated transcription regulation of DNA-templated transcription regulation of mitotic nuclear division regulation of transcription by RNA polymerase II trunk segmentation zygotic determination of anterior/posterior axis, embryo nucleus DNA-bin... |
cellular response to amine stimulus cellular response to arsenic-containing substance heme A biosynthetic process heme B biosynthetic process heme biosynthetic process heme O biosynthetic process protoporphyrinogen IX biosynthetic process response to platinum ion uroporphyrinogen III biosynthetic process | cytosol; mitochondrion | folic acid binding uroporphyrinogen-III synthase activity | Homo sapiens | 3D-structure Direct protein sequencing Disease variant Heme biosynthesis Lyase Porphyrin biosynthesis Reference proteome | MKVLLLKDAK | MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLPSFSEKLSHPEDYGGLIFTSPRAVEAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEGETCGNAEKLAEYICSRESSALPLLFPCGNLKREILPKALKDKGIAMESITVYQTVAHPGIQGNLNSYYSQQGVPASITFFSPSGLTYSLKHIQELSGDNIDQIKFAAIGPTTARALAAQGLPVSCTAESPTPQALATGIRKALQPHGCC | cellular response to amine stimulus cellular response to arsenic-containing substance heme A biosynthetic process heme B biosynthetic process heme biosynthetic process heme O biosynthetic process protoporphyrinogen IX biosynthetic process response to platinum ion uroporphyrinogen III biosynthetic process cytosol; mitoc... |
negative regulation of transcription by RNA polymerase II positive regulation of hydrogen peroxide biosynthetic process positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway regulation of transcription by RNA polymerase II | mitochondrion; nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding | Mus musculus | Alternative splicing Direct protein sequencing DNA-binding Metal-binding Nucleus Reference proteome Repeat Repressor Transcription Transcription regulation Zinc Zinc-finger | MSADSQSIAA | MSADSQSIAATENEEKSHEVPGNVQHCGDMLSGQEETVPLGTSQESTHIKAEPEEPHSEGASREDRTPGTQRWMSPCPGPKDKGPFLPGGVVPSPWTPVLSRGGRTRERKMAAALLTAWSQMPVTFEDVALYLSQEEWGRLDHTQQNFYRDVLQGKNGLALGAVEMGKVVPALAVATLEDTKSIRTRARWAPGEDPKCGQHVASGPGTKLTRDTGKAGQLKPAPSESRPLKTPEDSGPEKPSEGEEALKSGEEGLVPDGDTGKKTYKCEQCGKGFSWHSHLVTHRRTHTGEKPYTCTDCGKRFGRSSHLIQHQIIHTGEK... | negative regulation of transcription by RNA polymerase II positive regulation of hydrogen peroxide biosynthetic process positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway regulation of transcription by RNA polymerase II mitochondrion; nucleus DNA-binding transcr... |
antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to chemokine cellular response to gastrin disruption of cell wall in another organism gene expression liver regeneration midgut development negative regulation of cell population proliferation pancreas regeneration phosphatidylino... | basal part of cell; dendrite membrane; extracellular space; growth cone; neuronal cell body membrane; perinuclear region of cytoplasm; protein-containing complex; zymogen granule | growth factor activity identical protein binding molecular function inhibitor activity oligosaccharide binding peptidoglycan binding phosphatase binding protein phosphatase binding signaling receptor activity signaling receptor binding | Rattus norvegicus | Direct protein sequencing Disulfide bond Glycoprotein Lectin Pyrrolidone carboxylic acid Reference proteome Secreted Signal | MTRNKYFILL | MTRNKYFILLSCLMVLSPSQGQEAEEDLPSARITCPEGSNAYSSYCYYFMEDHLSWAEADLFCQNMNSGYLVSVLSQAEGNFLASLIKESGTTAANVWIGLHDPKNNRRWHWSSGSLFLYKSWDTGYPNNSNRGYCVSVTSNSGYKKWRDNSCDAQLSFVCKFKA | antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to chemokine cellular response to gastrin disruption of cell wall in another organism gene expression liver regeneration midgut development negative regulation of cell population proliferation pancreas regeneration phosphatidylino... |
AMP metabolic process GMP salvage IMP biosynthetic process IMP salvage response to organic substance | cytosol | AMP deaminase activity identical protein binding metal ion binding myosin heavy chain binding | Rattus norvegicus | Direct protein sequencing Hydrolase Metal-binding Nucleotide metabolism Phosphoprotein Reference proteome Zinc | MPLFKLTGQG | MPLFKLTGQGKQIDDAMRSFAEKVFASEVKDEGGRHEISPFDVDEICPISLREMQAHIFHMENLSMSMDGRRKRRFQGRKTVNLSIPQSETSSTKLSHIEEFISSSPTYESVPDFQRVQITGDYASGVTVEDFEVVCKGLYRALCIREKYMQKSFQRFPKTPSKYLRNIDGEALVAIESFYPVFTPPPKKGEDPFRREDLPANLGYHLKMKGGVIYIYPDEAAASRDEPKPYPYPNLDDFLDDMNFLLALIAQGPVKTYTHRRLKFLSSKFQVHQMLNEMDELKELKNNPHRDFYNCRKVDTHIHAAACMNQKHLLRFIK... | AMP metabolic process GMP salvage IMP biosynthetic process IMP salvage response to organic substance cytosol AMP deaminase activity identical protein binding metal ion binding myosin heavy chain binding Rattus norvegicus Direct protein sequencing Hydrolase Metal-binding Nucleotide metabolism Phosphoprotein Reference pr... |
chronic inflammatory response to antigenic stimulus circadian sleep/wake cycle one-carbon metabolic process response to hypoxia response to nutrient S-adenosylhomocysteine catabolic process S-adenosylmethionine cycle | cytosol; endoplasmic reticulum; melanosome; nucleus | adenosylhomocysteinase activity adenosylselenohomocysteinase activity adenyl nucleotide binding copper ion binding identical protein binding NAD binding protein self-association | Rattus norvegicus | 3D-structure Copper Cytoplasm Direct protein sequencing Endoplasmic reticulum Hydrolase Hydroxylation NAD Nucleus One-carbon metabolism Phosphoprotein Reference proteome | MADKLPYKVA | MADKLPYKVADIGLAAWGRKALDIAENEMPGLMRMREMYSASKPLKGARIAGCLHMTVETAVLIETLVALGAEVRWSSCNIFSTQDHAAAAIAKAGIPVFAWKGETDEEYLWCIEQTLHFKDGPLNMILDDGGDLTNLIHTKHPQLLSGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACKEGNIFVTTTGCVDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVN... | chronic inflammatory response to antigenic stimulus circadian sleep/wake cycle one-carbon metabolic process response to hypoxia response to nutrient S-adenosylhomocysteine catabolic process S-adenosylmethionine cycle cytosol; endoplasmic reticulum; melanosome; nucleus adenosylhomocysteinase activity adenosylselenohomoc... |
binding of sperm to zona pellucida blastocyst formation egg coat formation humoral immune response mediated by circulating immunoglobulin negative regulation of binding of sperm to zona pellucida negative regulation of DNA-templated transcription oocyte development positive regulation of acrosomal vesicle exocytosis po... | collagen-containing extracellular matrix; egg coat; extracellular matrix; extracellular space; plasma membrane | acrosin binding carbohydrate binding identical protein binding receptor ligand activity structural constituent of egg coat | Mus musculus | 3D-structure Cell membrane Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Extracellular matrix Glycoprotein Membrane Pyrrolidone carboxylic acid Receptor Reference proteome Secreted Signal Transmembrane Transmembrane helix | MASSYFLFLC | MASSYFLFLCLLLCGGPELCNSQTLWLLPGGTPTPVGSSSPVKVECLEAELVVTVSRDLFGTGKLVQPGDLTLGSEGCQPRVSVDTDVVRFNAQLHECSSRVQMTKDALVYSTFLLHDPRPVSGLSILRTNRVEVPIECRYPRQGNVSSHPIQPTWVPFRATVSSEEKLAFSLRLMEENWNTEKSAPTFHLGEVAHLQAEVQTGSHLPLQLFVDHCVATPSPLPDPNSSPYHFIVDFHGCLVDGLSESFSAFQVPRPRPETLQFTVDVFHFANSSRNTLYITCHLKVAPANQIPDKLNKACSFNKTSQSWLPVEGDADIC... | binding of sperm to zona pellucida blastocyst formation egg coat formation humoral immune response mediated by circulating immunoglobulin negative regulation of binding of sperm to zona pellucida negative regulation of DNA-templated transcription oocyte development positive regulation of acrosomal vesicle exocytosis po... |
embryonic placenta development embryonic placenta morphogenesis glucose metabolic process in utero embryonic development negative regulation of muscle cell differentiation negative regulation of transcription by RNA polymerase II ossification positive regulation of cell division positive regulation of cell population p... | extracellular space | growth factor activity hormone activity integrin binding | Ovis aries | Carbohydrate metabolism Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Glucose metabolism Glycoprotein Growth factor Hormone Mitogen Osteogenesis Reference proteome Secreted Signal | MGITAGKSML | MGITAGKSMLALLAFLAFASCCYAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPSSRINRRSRGIVEECCFRSCDLALLETYCAAPAKSERDVSASTTVLPDDFTAYPVGKFFQSDTWKQSTQRLRRGLPAFLRARRGRTLAKELEALREAKSHRPLIALPTQDPATHGGASSEASSD | embryonic placenta development embryonic placenta morphogenesis glucose metabolic process in utero embryonic development negative regulation of muscle cell differentiation negative regulation of transcription by RNA polymerase II ossification positive regulation of cell division positive regulation of cell population p... |
angiogenesis animal organ morphogenesis cartilage condensation cell differentiation fibroblast growth factor receptor signaling pathway myoblast differentiation positive regulation of cell division positive regulation of cell population proliferation positive regulation of gene expression positive regulation of protein... | cytoplasm; extracellular region; extracellular space; sarcolemma | fibroblast growth factor receptor binding growth factor activity | Homo sapiens | Angiogenesis Developmental protein Differentiation Disulfide bond Glycoprotein Growth factor Mitogen Proto-oncogene Reference proteome Secreted Signal | MALGQKLFIT | MALGQKLFITMSRGAGRLQGTLWALVFLGILVGMVVPSPAGTRANNTLLDSRGWGTLLSRSRAGLAGEIAGVNWESGYLVGIKRQRRLYCNVGIGFHLQVLPDGRISGTHEENPYSLLEISTVERGVVSLFGVRSALFVAMNSKGRLYATPSFQEECKFRETLLPNNYNAYESDLYQGTYIALSKYGRVKRGSKVSPIMTVTHFLPRI | angiogenesis animal organ morphogenesis cartilage condensation cell differentiation fibroblast growth factor receptor signaling pathway myoblast differentiation positive regulation of cell division positive regulation of cell population proliferation positive regulation of gene expression positive regulation of protein... |
formaldehyde catabolic process | cytoplasmic vesicle; cytosol; endoplasmic reticulum lumen; extracellular exosome | carboxylic ester hydrolase activity hydrolase activity, acting on ester bonds identical protein binding methylumbelliferyl-acetate deacetylase activity S-formylglutathione hydrolase activity | Homo sapiens | 3D-structure Acetylation Cytoplasm Cytoplasmic vesicle Direct protein sequencing Hydrolase Reference proteome Serine esterase | MALKQISSNK | MALKQISSNKCFGGLQKVFEHDSVELNCKMKFAVYLPPKAETGKCPALYWLSGLTCTEQNFISKSGYHQSASEHGLVVIAPDTSPRGCNIKGEDESWDFGTGAGFYVDATEDPWKTNYRMYSYVTEELPQLINANFPVDPQRMSIFGHSMGGHGALICALKNPGKYKSVSAFAPICNPVLCPWGKKAFSGYLGTDQSKWKAYDATHLVKSYPGSQLDILIDQGKDDQFLLDGQLLPDNFIAACTEKKIPVVFRLQEGYDHSYYFIATFITDHIRHHAKYLNA | formaldehyde catabolic process cytoplasmic vesicle; cytosol; endoplasmic reticulum lumen; extracellular exosome carboxylic ester hydrolase activity hydrolase activity, acting on ester bonds identical protein binding methylumbelliferyl-acetate deacetylase activity S-formylglutathione hydrolase activity Homo sapiens 3D-s... |
chromosome condensation defense response to Gram-positive bacterium negative regulation of DNA recombination negative regulation of gene expression nucleosome assembly regulation of gene expression | chromosome, telomeric region; cytoplasm; nucleosome; nucleus | double-stranded DNA binding H3K27me3 modified histone binding nucleosomal DNA binding structural constituent of chromatin | Caenorhabditis elegans | Acetylation Chromosome Cytoplasm Direct protein sequencing DNA-binding Methylation Nucleus Reference proteome | MSDSAVVAAA | MSDSAVVAAAVEPKVPKAKAAKAAKPTKVAKAKAPVAHPPYINMIKEAIKQLKDRKGASKQAILKFISQNYKLGDNVIQINAHLRQALKRGVTSKALVQAAGSGANGRFRVPEKAAAAKKPAAAKKPAAAKKPAAAKKATGEKKAKKPAAAKPKKAATGDKKVKKAKSPKKVAKPAAKKVAKSPAKKAAPKKIAKPAAKKAAKPAAKA | chromosome condensation defense response to Gram-positive bacterium negative regulation of DNA recombination negative regulation of gene expression nucleosome assembly regulation of gene expression chromosome, telomeric region; cytoplasm; nucleosome; nucleus double-stranded DNA binding H3K27me3 modified histone binding... |
long-chain fatty acid transport | cytosol; mitochondrial matrix; nucleus | long-chain fatty acid binding | Bos taurus | 3D-structure Acetylation Cytoplasm Direct protein sequencing Lipid-binding Mitochondrion Phosphoprotein Reference proteome Transport | MVDAFVGTWK | MVDAFVGTWKLVDSKNFDDYMKSLGVGFATRQVGNMTKPTTIIEVNGDTVIIKTQSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHVQKWNGQETSLVREMVDGKLILTLTHGTAVCTRTYEKQA | long-chain fatty acid transport cytosol; mitochondrial matrix; nucleus long-chain fatty acid binding Bos taurus 3D-structure Acetylation Cytoplasm Direct protein sequencing Lipid-binding Mitochondrion Phosphoprotein Reference proteome Transport MVDAFVGTWK MVDAFVGTWKLVDSKNFDDYMKSLGVGFATRQVGNMTKPTTIIEVNGDTVIIKTQSTFKNTEIS... |
determination of adult lifespan regulation of autophagy of mitochondrion regulation of synaptic plasticity regulation of terminal button organization | peroxisome | copper ion binding protein homodimerization activity superoxide dismutase activity | Drosophila virilis | Antioxidant Copper Cytoplasm Disulfide bond Metal-binding Oxidoreductase Reference proteome Zinc | MVVKAVCVIN | MVVKAVCVINGDAKGTVFFEQEGEGCPVKVTGEVTGLAKGQHGFHVHEFGDNTNGCMSSGPHFNPYQKEHGAPTDENRHLGDLGNIIANGDGPTPVNICDCKITLLGANSIIGRTVVVHADPDDLGKGGHELSKTTGNAGARIGCGVIGIAKI | determination of adult lifespan regulation of autophagy of mitochondrion regulation of synaptic plasticity regulation of terminal button organization peroxisome copper ion binding protein homodimerization activity superoxide dismutase activity Drosophila virilis Antioxidant Copper Cytoplasm Disulfide bond Metal-binding... |
photorespiration photosynthesis reductive pentose-phosphate cycle response to cold ribulose bisphosphate carboxylase complex assembly | apoplast; chloroplast; chloroplast envelope; chloroplast membrane; chloroplast stroma; chloroplast thylakoid membrane; cytosolic ribosome; mitochondrion; thylakoid; thylakoid lumen | copper ion binding mRNA binding ribulose-bisphosphate carboxylase activity salicylic acid binding | Arabidopsis thaliana | Alternative splicing Calvin cycle Carbon dioxide fixation Chloroplast Membrane Phosphoprotein Photorespiration Photosynthesis Plastid Reference proteome Transit peptide | MASSMLSSAT | MASSMLSSATMVASPAQATMVAPFNGLKSSAAFPATRKANNDITSITSNGGRVNCMQVWPPIGKKKFETLSYLPDLTDSELAKEVDYLIRNKWIPCVEFELEHGFVYREHGNSPGYYDGRYWTMWKLPLFGCTDSAQVLKEVEECKKEYPNAFIRIIGFDNTRQVQCISFIAYKPPSFTG | photorespiration photosynthesis reductive pentose-phosphate cycle response to cold ribulose bisphosphate carboxylase complex assembly apoplast; chloroplast; chloroplast envelope; chloroplast membrane; chloroplast stroma; chloroplast thylakoid membrane; cytosolic ribosome; mitochondrion; thylakoid; thylakoid lumen coppe... |
cell surface pattern recognition receptor signaling pathway cellular response to diacyl bacterial lipopeptide cellular response to lipopolysaccharide cellular response to lipoteichoic acid cellular response to molecule of bacterial origin cellular response to triacyl bacterial lipopeptide inflammatory response innate i... | cell surface; external side of plasma membrane; extracellular space; Golgi apparatus; lipopolysaccharide receptor complex; membrane raft | lipopolysaccharide binding lipopolysaccharide immune receptor activity lipoteichoic acid binding | Mus musculus | 3D-structure Cell membrane Disulfide bond Glycoprotein Golgi apparatus GPI-anchor Immunity Inflammatory response Innate immunity Leucine-rich repeat Lipoprotein Membrane Reference proteome Repeat Secreted Signal | MERVLGLLLL | MERVLGLLLLLLVHASPAPPEPCELDEESCSCNFSDPKPDWSSAFNCLGAADVELYGGGRSLEYLLKRVDTEADLGQFTDIIKSLSLKRLTVRAARIPSRILFGALRVLGISGLQELTLENLEVTGTAPPPLLEATGPDLNILNLRNVSWATRDAWLAELQQWLKPGLKVLSIAQAHSLNFSCEQVRVFPALSTLDLSDNPELGERGLISALCPLKFPTLQVLALRNAGMETPSGVCSALAAARVQLQGLDLSHNSLRDAAGAPSCDWPSQLNSLNLSFTGLKQVPKGLPAKLSVLDLSYNRLDRNPSPDELPQVGNLSL... | cell surface pattern recognition receptor signaling pathway cellular response to diacyl bacterial lipopeptide cellular response to lipopolysaccharide cellular response to lipoteichoic acid cellular response to molecule of bacterial origin cellular response to triacyl bacterial lipopeptide inflammatory response innate i... |
calcium ion homeostasis hyperosmotic salinity response hypotonic salinity response magnesium ion homeostasis photoperiodism positive regulation of phagocytosis positive regulation of superoxide anion generation regulation of immunoglobulin production response to estradiol response to food response to light stimulus res... | extracellular space | growth hormone receptor binding hormone activity metal ion binding | Salmo salar | Disulfide bond Hormone Metal-binding Reference proteome Secreted Signal Zinc | MGQVFLLMPV | MGQVFLLMPVLLVSCFLSQGAAMENQRLFNIAVNRVQHLHLMAQKMFNDFEGTLLPDERRQLNKIFLLDFCNSDSIVSPIDKLETQKSSVLKLLHISFRLIESWEYPSQTLTISNSLMVRNSNQISEKLSDLKVGINLLIKGSQDGVLSLDDNDSQQLPPYGNYYQNLGGDGNVRRNYELLACFKKDMHKVETYLTVAKCRKSLEANCTL | calcium ion homeostasis hyperosmotic salinity response hypotonic salinity response magnesium ion homeostasis photoperiodism positive regulation of phagocytosis positive regulation of superoxide anion generation regulation of immunoglobulin production response to estradiol response to food response to light stimulus res... |
cell division meiotic nuclear division mitotic cell cycle phase transition mitotic DNA damage checkpoint signaling negative regulation of ascospore formation negative regulation of meiotic cell cycle positive regulation of G2/M transition of mitotic cell cycle positive regulation of mitotic sister chromatid biorientati... | chromatin; chromosome, telomeric repeat region; cyclin-dependent protein kinase holoenzyme complex; cytoplasm; meiotic spindle; mitotic spindle; mitotic spindle midzone; mitotic spindle pole body; new mitotic spindle pole body; nuclear periphery; nucleolar peripheral inclusion body; nucleolus; nucleoplasm; nucleus; old... | cyclin-dependent protein serine/threonine kinase activator activity cyclin-dependent protein serine/threonine kinase regulator activity | Schizosaccharomyces pombe | Cell cycle Cell division Cyclin Cytoplasm Cytoskeleton Mitosis Nucleus Reference proteome | MTTRRLTRQH | MTTRRLTRQHLLANTLGNNDENHPSNHIARAKSSLHSSENSLVNGKKATVSSTNVPKKRHALDDVSNFHNKEGVPLASKNTNVRHTTASVSTRRALEEKSIIPATDDEPASKKRRQPSVFNSSVPSLPQHLSTKSHSVSTHGVDAFHKDQATIPKKLKKDVDERVVSKDIPKLHRDSVESPESQDWDDLDAEDWADPLMVSEYVVDIFEYLNELEIETMPSPTYMDRQKELAWKMRGILTDWLIEVHSRFRLLPETLFLAVNIIDRFLSLRVCSLNKLQLVGIAALFIASKYEEVMCPSVQNFVYMADGGYDEEEILQAE... | cell division meiotic nuclear division mitotic cell cycle phase transition mitotic DNA damage checkpoint signaling negative regulation of ascospore formation negative regulation of meiotic cell cycle positive regulation of G2/M transition of mitotic cell cycle positive regulation of mitotic sister chromatid biorientati... |
establishment or maintenance of cell polarity one-carbon metabolic process S-adenosylmethionine cycle | actin rod; cell cortex; cytoplasm; cytosol; extracellular matrix; nucleus; phagocytic vesicle | adenosylhomocysteinase activity cAMP binding | Dictyostelium discoideum | Hydrolase NAD One-carbon metabolism Reference proteome | MTKLHYKVKD | MTKLHYKVKDISLAAWGRKEIEIAENEMPGLMTLRKKYGPAQILKGARIAGCLHMTIQTAVLIETLTALGAQVQWSSCNIFSTQDQAAAAIAATGVPVYAWKGETEEEYNWCVEQTIVFQDGQPLNMILDDGGDLTNLVHEKYPQFLAGIKGISEETTTGVHNLYKMFKEGKLKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQSLSKMGARVLVTEIDPINALQACMDGYQIVTMETAAPLSNIFVTTTGCRDIVRGEHFAVMKEDAIVCNIGHFDCEIDVAWLNANAKKDTV... | establishment or maintenance of cell polarity one-carbon metabolic process S-adenosylmethionine cycle actin rod; cell cortex; cytoplasm; cytosol; extracellular matrix; nucleus; phagocytic vesicle adenosylhomocysteinase activity cAMP binding Dictyostelium discoideum Hydrolase NAD One-carbon metabolism Reference proteome... |
circadian rhythm defense response to tumor cell defense response to virus granzyme-mediated programmed cell death signaling pathway immune response to tumor cell immunological synapse formation killing of cells of another organism positive regulation of killing of cells of another organism protein homooligomerization p... | cytolytic granule; cytoplasmic vesicle; cytosol; endosome lumen; extracellular space; immunological synapse; membrane; plasma membrane | calcium ion binding identical protein binding pore-forming activity wide pore channel activity | Mus musculus | 3D-structure Calcium Cell membrane Cytolysis Direct protein sequencing Disulfide bond EGF-like domain Endosome Glycoprotein Lysosome Membrane Metal-binding Reference proteome Secreted Signal Transmembrane Transmembrane beta strand | MATCLFLLGL | MATCLFLLGLFLLLPRPVPAPCYTATRSECKQKHKFVPGVWMAGEGMDVTTLRRSGSFPVNTQRFLRPDRTCTLCKNSLMRDATQRLPVAITHWRPHSSHCQRNVAAAKVHSTEGVAREAAANINNDWRVGLDVNPRPEANMRASVAGSHSKVANFAAEKTYQDQYNFNSDTVECRMYSFRLVQKPPLHLDFKKALRALPRNFNSSTEHAYHRLISSYGTHFITAVDLGGRISVLTALRTCQLTLNGLTADEVGDCLNVEAQVSIGAQASVSSEYKACEEKKKQHKMATSFHQTYRERHVEVLGGPLDSTHDLLFGNQAT... | circadian rhythm defense response to tumor cell defense response to virus granzyme-mediated programmed cell death signaling pathway immune response to tumor cell immunological synapse formation killing of cells of another organism positive regulation of killing of cells of another organism protein homooligomerization p... |
adenylate cyclase-activating G protein-coupled receptor signaling pathway ascospore formation glucose mediated signaling pathway hexose mediated signaling invasive growth in response to glucose limitation protein kinase A signaling pseudohyphal growth regulation of cell size signal transduction | cytosol; heterotrimeric G-protein complex; mitochondrion; plasma membrane | G protein-coupled receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity metal ion binding | Saccharomyces cerevisiae | Cell membrane GTP-binding Lipoprotein Magnesium Membrane Metal-binding Myristate Nucleotide-binding Palmitate Reference proteome Transducer | MGLCASSEKN | MGLCASSEKNGSTPDTQTASAGSDNVGKAKVPPKQEPQKTVRTVNTANQQEKQQQRQQQPSPHNVKDRKEQNGSINNAISPTATANTSGSQQINIDSALRDRSSNVAAQPSLSDASSGSNDKELKVLLLGAGESGKSTVLQQLKILHQNGFSEQEIKEYIPLIYQNLLEIGRNLIQARTRFNVNLEPECELTQQDLSRTMSYEMPNNYTGQFPEDIAGVISTLWALPSTQDLVNGPNASKFYLMDSTPYFMENFTRITSPNYRPTQQDILRSRQMTSGIFDTVIDMGSDIKMHIYDVGGQRSERKKWIHCFDNVTLVIFC... | adenylate cyclase-activating G protein-coupled receptor signaling pathway ascospore formation glucose mediated signaling pathway hexose mediated signaling invasive growth in response to glucose limitation protein kinase A signaling pseudohyphal growth regulation of cell size signal transduction cytosol; heterotrimeric ... |
adenylate cyclase-modulating G protein-coupled receptor signaling pathway cell cycle cell division cellular response to forskolin G protein-coupled receptor signaling pathway negative regulation of synaptic transmission positive regulation of protein localization to cell cortex regulation of cAMP-mediated signaling reg... | cell cortex; centrosome; cytoplasm; heterotrimeric G-protein complex; midbody; nucleus; plasma membrane; protein-containing complex | D2 dopamine receptor binding G protein-coupled receptor binding G protein-coupled serotonin receptor binding G-protein beta/gamma-subunit complex binding GDP binding GTP binding GTPase activating protein binding GTPase activity magnesium ion binding | Rattus norvegicus | 3D-structure Cell cycle Cell division Cell membrane Cytoplasm Cytoskeleton GTP-binding Lipoprotein Magnesium Membrane Metal-binding Mitosis Myristate Nucleotide-binding Nucleus Palmitate Reference proteome Transducer Transport | MGCTLSAEDK | MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDAARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIY... | adenylate cyclase-modulating G protein-coupled receptor signaling pathway cell cycle cell division cellular response to forskolin G protein-coupled receptor signaling pathway negative regulation of synaptic transmission positive regulation of protein localization to cell cortex regulation of cAMP-mediated signaling reg... |
apoptotic process cell differentiation embryonic digestive tract development embryonic eye morphogenesis embryonic hindlimb morphogenesis glandular epithelial cell development growth plate cartilage development hormone-mediated signaling pathway multicellular organism growth negative regulation of chondrocyte different... | chromatin; cytoplasm; nucleoplasm; nucleus | DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific heterocyclic compound binding nuclear receptor activity nuclear retinoid X receptor binding protein-containing complex binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA bin... | Homo sapiens | 3D-structure Alternative splicing Cytoplasm Disease variant DNA-binding Metal-binding Microphthalmia Nucleus Phosphoprotein Proto-oncogene Receptor Reference proteome Transcription Transcription regulation Zinc Zinc-finger | MTTSGHACPV | MTTSGHACPVPAVNGHMTHYPATPYPLLFPPVIGGLSLPPLHGLHGHPPPSGCSTPSPATIETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMIYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKETSKQECTESYEMTAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLE... | apoptotic process cell differentiation embryonic digestive tract development embryonic eye morphogenesis embryonic hindlimb morphogenesis glandular epithelial cell development growth plate cartilage development hormone-mediated signaling pathway multicellular organism growth negative regulation of chondrocyte different... |
cell differentiation cellular response to thyroid hormone stimulus DNA-templated transcription female courtship behavior mRNA transcription by RNA polymerase II negative regulation of female receptivity negative regulation of transcription by RNA polymerase II positive regulation of thyroid hormone mediated signaling p... | chromatin; nuclear body; nucleoplasm; nucleus; RNA polymerase II transcription regulator complex | chromatin DNA binding DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific enzyme binding nuclear receptor activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding thyroid hormone b... | Homo sapiens | 3D-structure Alternative splicing Deafness Disease variant DNA-binding Metal-binding Nucleus Receptor Reference proteome Transcription Transcription regulation Zinc Zinc-finger | MTPNSMTENG | MTPNSMTENGLTAWDKPKHCPDREHDWKLVGMSEACLHRKSHSERRSTLKNEQSSPHLIQTTWTSSIFHLDHDDVNDQSVSSAQTFQTEEKKCKGYIPSYLDKDELCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVR... | cell differentiation cellular response to thyroid hormone stimulus DNA-templated transcription female courtship behavior mRNA transcription by RNA polymerase II negative regulation of female receptivity negative regulation of transcription by RNA polymerase II positive regulation of thyroid hormone mediated signaling p... |
negative regulation of neuron apoptotic process negative regulation of proteasomal protein catabolic process negative regulation of protein ubiquitination phosphorylation regulation of circadian rhythm regulation of response to food response to morphine response to pain rhythmic process | cytosol; dendrite; perinuclear region of cytoplasm; plasma membrane; synapse | ATP binding diacylglycerol-dependent serine/threonine kinase activity protein serine kinase activity zinc ion binding | Oryctolagus cuniculus | ATP-binding Biological rhythms Calcium Cell membrane Cell projection Cytoplasm Kinase Membrane Metal-binding Nucleotide-binding Phosphoprotein Reference proteome Repeat Serine/threonine-protein kinase Synapse Synaptosome Transferase Ubl conjugation Zinc Zinc-finger | MAGLGPGGGD | MAGLGPGGGDSEGGPRPLFCRKGALRQKVVHEVKSHKFTARFFKQPTFCSHCTDFIWGIGKQGLQCQVCSFVVHRRCHEFVTFECPGAGKGPQTDDPRNKHKFRLHSYSSPTFCDHCGSLLYGLVHQGMKCSCCEMNVHRRCVRTVPSLCGVDHTERRGRLQLEIRAPTSDEIHVTVGEARNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTRTVKATLNPVWNETFVFNLKPGDVERRLSVEVWDWDRTSRNDFMGAMSFGVSELLKAPVDGWYKLLNQEEGEYYNVPVADADNCSLLQKFEACNYPLELYERVRMGPS... | negative regulation of neuron apoptotic process negative regulation of proteasomal protein catabolic process negative regulation of protein ubiquitination phosphorylation regulation of circadian rhythm regulation of response to food response to morphine response to pain rhythmic process cytosol; dendrite; perinuclear r... |
cell adhesion cell cycle cell division lipopolysaccharide-mediated signaling pathway phosphorylation positive regulation of actin filament polymerization positive regulation of cytokinesis positive regulation of epithelial cell migration positive regulation of fibroblast migration positive regulation of wound healing T... | cell periphery; cytoskeleton; nucleus; perinuclear region of cytoplasm; plasma membrane | actin monomer binding ATP binding diacylglycerol-dependent, calcium-independent serine/threonine kinase activity metal ion binding protein kinase activity protein serine kinase activity | Oryctolagus cuniculus | ATP-binding Cell adhesion Cell cycle Cell division Cell membrane Cytoplasm Cytoskeleton Immunity Kinase Membrane Metal-binding Nucleotide-binding Nucleus Phosphoprotein Reference proteome Repeat Serine/threonine-protein kinase Transferase Zinc Zinc-finger | MVVFNGLLKI | MVVFNGLLKIKICEAVSLKPTAWSLRHAVGPRPQTFLLDPYIALNVDDSRIGQTATKQKTNSPAWHDEFVTDVCNGRKIELAVFHDAPIGYDDFVANCTIQFEELLQNGSRHFEDWIDLEPEGKVYVIIDLSGSSGEAPKDNEERVFRERMRPRKRQGAVRRRVHQVNGHKFMATYLRQPTYCSHCRDFIWGVIGKQGYQCQVCTCVVHKRCHELIITKVAGLKKQETPDEVGSQRFSVNMPHKFGIHNYKVPTFCDHCGSLLWGLLRQGLQCKVCKMNVHRRCETNVAPNCGVDARGIAKVLADLGVTPDKITNSGQRR... | cell adhesion cell cycle cell division lipopolysaccharide-mediated signaling pathway phosphorylation positive regulation of actin filament polymerization positive regulation of cytokinesis positive regulation of epithelial cell migration positive regulation of fibroblast migration positive regulation of wound healing T... |
cell migration face morphogenesis leukocyte differentiation negative regulation of Schwann cell migration positive regulation of angiogenesis positive regulation of endothelial cell migration positive regulation of endothelial cell-matrix adhesion via fibronectin positive regulation of vasculogenesis regulation of ERK1... | cytosol; plasma membrane | GDP binding GTP binding GTPase activity protein-containing complex binding | Mus musculus | Cell membrane GTP-binding Hydrolase Lipoprotein Membrane Methylation Nucleotide-binding Palmitate Prenylation Reference proteome | MSSGAASGTG | MSSGAASGTGRGRPRGGGPGPRDPPPGETHKLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIEDSYTKICTVDGIPARLDILDTAGQEEFGAMREQYMRAGNGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPIVLVGNKADLENQRQVLRSEASSFSASHHMTYFEASAKLRLNVDEAFEQLVRAVRKYQEQELPPSPPSAPRKKDGGCPCVLL | cell migration face morphogenesis leukocyte differentiation negative regulation of Schwann cell migration positive regulation of angiogenesis positive regulation of endothelial cell migration positive regulation of endothelial cell-matrix adhesion via fibronectin positive regulation of vasculogenesis regulation of ERK1... |
cellular response to pheromone mating type determination negative regulation of conjugation with zygote positive regulation of meiotic cell cycle positive regulation of transcription by RNA polymerase II protein localization to nucleus regulation of cell cycle switching, mitotic to meiotic cell cycle signal transductio... | chromatin; nucleus; Pi Mi complex | DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific | Schizosaccharomyces pombe | DNA-binding Homeobox Nucleus Stress response | MKRVAVLLKT | MKRVAVLLKTVMCEFLKCDYNGYDRIISLLRRILTLICTPNLNGLTIKRVIDSMQSLEYIKQTCNFKLQMCISSMAFKRNNALQNCNHYAWCDDHCSDIGRPMTTVRGQCSKCTKPHLMRWLLLHYDNPYPSNSEFYDLSAATGLTRTQLRNWFSNRRR | cellular response to pheromone mating type determination negative regulation of conjugation with zygote positive regulation of meiotic cell cycle positive regulation of transcription by RNA polymerase II protein localization to nucleus regulation of cell cycle switching, mitotic to meiotic cell cycle signal transductio... |
carbohydrate metabolic process isoleucine transport L-alanine import across plasma membrane L-histidine transport L-leucine import across plasma membrane leucine import across plasma membrane leucine transport methionine transport neutral amino acid transport phenylalanine transport proline transport response to exogen... | amino acid transport complex; anchoring junction; apical plasma membrane; apical pole of neuron; basal plasma membrane; basolateral plasma membrane; cell surface; lysosomal membrane; melanosome; neuronal cell body; nucleoplasm; plasma membrane; synapse | aromatic amino acid transmembrane transporter activity double-stranded RNA binding exogenous protein binding L-alanine transmembrane transporter activity L-leucine transmembrane transporter activity neutral L-amino acid secondary active transmembrane transporter activity neutral L-amino acid transmembrane transporter a... | Mus musculus | 3D-structure Alternative splicing Amino-acid transport Cell junction Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Isopeptide bond Lysosome Membrane Phosphoprotein Reference proteome Signal-anchor Transmembrane Transmembrane helix Transport Ubl conjugation | MSQDTEVDMK | MSQDTEVDMKDVELNELEPEKQPMNAADGAAAGEKNGLVKIKVAEDETEAGVKFTGLSKEELLKVAGSPGWVRTRWALLLLFWLGWLGMLAGAVVIIVRAPRCRELPVQRWWHKGALYRIGDLQAFVGRDAGGIAGLKSHLEYLSTLKVKGLVLGPIHKNQKDEINETDLKQINPTLGSQEDFKDLLQSAKKKSIHIILDLTPNYQGQNAWFLPAQADIVATKMKEALSSWLQDGVDGFQFRDVGKLMNAPLYLAEWQNITKNLSEDRLLIAGTESSDLQQIVNILESTSDLLLTSSYLSNSTFTGERTESLVTRFLNAT... | carbohydrate metabolic process isoleucine transport L-alanine import across plasma membrane L-histidine transport L-leucine import across plasma membrane leucine import across plasma membrane leucine transport methionine transport neutral amino acid transport phenylalanine transport proline transport response to exogen... |
chromatin organization protein localization to CENP-A containing chromatin | CENP-A containing nucleosome; cytosol; extracellular space; nucleoplasm; nucleosome; nucleus | DNA binding identical protein binding protein heterodimerization activity structural constituent of chromatin | Mus musculus | Acetylation ADP-ribosylation Chromosome DNA-binding Glycoprotein Hydroxylation Isopeptide bond Methylation Nucleosome core Nucleus Phosphoprotein Reference proteome Ubl conjugation | MPEPAKSAPA | MPEPAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIASEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK | chromatin organization protein localization to CENP-A containing chromatin CENP-A containing nucleosome; cytosol; extracellular space; nucleoplasm; nucleosome; nucleus DNA binding identical protein binding protein heterodimerization activity structural constituent of chromatin Mus musculus Acetylation ADP-ribosylation ... |
chromatin remodeling flagellated sperm motility heterochromatin formation negative regulation of DNA-templated transcription nucleosome disassembly positive regulation of protein processing sexual reproduction single strand break repair sperm DNA condensation spermatid development spermatid nucleus elongation spermatog... | male germ cell nucleus; nucleosome; nucleus | DNA binding | Mus musculus | Chromosome Developmental protein Differentiation DNA-binding Nucleosome core Nucleus Phosphoprotein Reference proteome Spermatogenesis | MSTSRKLKTH | MSTSRKLKTHGMRRGKNRAPHKGVKRGGSKRKYRKSVLKSRKRGDDASRNYRSHL | chromatin remodeling flagellated sperm motility heterochromatin formation negative regulation of DNA-templated transcription nucleosome disassembly positive regulation of protein processing sexual reproduction single strand break repair sperm DNA condensation spermatid development spermatid nucleus elongation spermatog... |
cerebellum development glutamate biosynthetic process glutamate catabolic process glutamine metabolic process long-term memory positive regulation of insulin secretion response to aluminum ion tricarboxylic acid metabolic process | cytoplasm; endoplasmic reticulum; mitochondrial matrix; mitochondrion | ADP binding ATP binding enzyme binding glutamate dehydrogenase (NAD+) activity glutamate dehydrogenase (NADP+) activity glutamate dehydrogenase activity GTP binding leucine binding NAD+ binding protein homodimerization activity | Rattus norvegicus | Acetylation ADP-ribosylation ATP-binding Direct protein sequencing Endoplasmic reticulum GTP-binding Hydroxylation Mitochondrion NADP Nucleotide-binding Oxidoreductase Phosphoprotein Reference proteome Transit peptide | MYRRLGEVLL | MYRRLGEVLLLSRAGPAALGSAAADSAALLGWARGQPSAVPQPGLTPVARRHYSEAATDREDDPNFFKMVEGFFDRGASIVEDKLVEDLKTRENEEQKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGLGDKTFVVQGFGNVGLHSMRYL... | cerebellum development glutamate biosynthetic process glutamate catabolic process glutamine metabolic process long-term memory positive regulation of insulin secretion response to aluminum ion tricarboxylic acid metabolic process cytoplasm; endoplasmic reticulum; mitochondrial matrix; mitochondrion ADP binding ATP bind... |
adaptive thermogenesis brown fat cell differentiation cellular response to cold cellular response to fatty acid cellular response to hormone stimulus cellular response to reactive oxygen species diet induced thermogenesis mitochondrial transmembrane transport positive regulation of cold-induced thermogenesis proton tra... | mitochondrial inner membrane | cardiolipin binding long-chain fatty acid binding oxidative phosphorylation uncoupler activity proton transmembrane transporter activity purine ribonucleotide binding | Bos taurus | Ion channel Ion transport Membrane Mitochondrion Mitochondrion inner membrane Oxidation Reference proteome Repeat Transmembrane Transmembrane helix Transport | MVGHTESDVP | MVGHTESDVPPTMAVKIFSAGVAACVADIITFPLDTAKVRLQVGSAIQGECLISSAIRYKGVLGTIITLAKTEGPVKLYSGLPAGLQRQISFASLRIGLYDTVQEFFTTGKEASLGSKISAGLMTGGVAVFIGQPTEVVKVRLQAQSHLHGPKPRYTGTYNAYRIIATTEGLTGLWKGTTPNLTRNVIINCTELVTYDLMKEALVKNKLLADDVPCHFVSAVVAGFCTTVLSSPVDVVKTRFVNSSPGQYTSVPNCAMMMLTREGPSAFFKGFVPSFLRLGSWNIIMFVCFEQLKQELMKSRHTMDCAT | adaptive thermogenesis brown fat cell differentiation cellular response to cold cellular response to fatty acid cellular response to hormone stimulus cellular response to reactive oxygen species diet induced thermogenesis mitochondrial transmembrane transport positive regulation of cold-induced thermogenesis proton tra... |
DNA duplex unwinding error-free postreplication DNA repair error-free translesion synthesis error-prone translesion synthesis postreplication repair protein monoubiquitination | chromatin; nucleus; Rad6-Rad18 complex | metal ion binding single-stranded DNA binding ubiquitin protein ligase activity | Saccharomyces cerevisiae | DNA damage DNA repair DNA-binding Isopeptide bond Metal-binding Nucleus Phosphoprotein Reference proteome Transferase Ubl conjugation Ubl conjugation pathway Zinc Zinc-finger | MDHQITTASD | MDHQITTASDFTTTSIPSLYQLDTLLRCHICKDFLKVPVLTPCGHTFCSLCIRTHLNNQPNCPLCLFEFRESLLRSEFLVSEIIQSYTSLRSSLLDALRIPKPTPVPENEEVPGPENSSWIELISESESDSVNAADDDLQIVATSERKLAKRSMTDILPLSSKPSKRNFAMFRSERIKKKSKPNEQMAQCPICQQFYPLKALEKTHLDECLTLQSLGKKPKISTTFPTESNPHNKSSSRFKVRTPEVDKSSCGETSHVDKYLNSMMSAEHQRLPKINFTSMTQSQIKQKLSSLGLSTNGTRQNMIKRYNHYEMLWNSNFC... | DNA duplex unwinding error-free postreplication DNA repair error-free translesion synthesis error-prone translesion synthesis postreplication repair protein monoubiquitination chromatin; nucleus; Rad6-Rad18 complex metal ion binding single-stranded DNA binding ubiquitin protein ligase activity Saccharomyces cerevisiae ... |
fungal-type cell wall organization | cell periphery; extracellular region; fungal-type cell wall; fungal-type vacuole; side of membrane | structural constituent of cell wall | Saccharomyces cerevisiae | Cell wall Glycoprotein GPI-anchor Lipoprotein Membrane Reference proteome Repeat Secreted Signal Stress response | MAYTKIALFA | MAYTKIALFAAIAALASAQTQDQINELNVILNDVKSHLQEYISLASDSSSGFSLSSMPAGVLDIGMALASATDDSYTTLYSEVDFAGVSKMLTMVPWYSSRLEPALKSLNGDASSSAAPSSSAAPTSSAAPSSSAAPTSSAASSSSEAKSSSAAPSSSEAKSSSAAPSSSEAKSSSAAPSSSEAKSSSAAPSSTEAKITSAAPSSTGAKTSAISQITDGQIQATKAVSEQTENGAAKAFVGMGAGVVAAAAMLL | fungal-type cell wall organization cell periphery; extracellular region; fungal-type cell wall; fungal-type vacuole; side of membrane structural constituent of cell wall Saccharomyces cerevisiae Cell wall Glycoprotein GPI-anchor Lipoprotein Membrane Reference proteome Repeat Secreted Signal Stress response MAYTKIALFA ... |
animal organ morphogenesis creatine biosynthetic process embryonic liver development methylation regulation of multicellular organism growth S-adenosylhomocysteine metabolic process S-adenosylmethionine metabolic process spermatogenesis | cytoplasm; nucleus | guanidinoacetate N-methyltransferase activity identical protein binding S-adenosylmethionine-dependent methyltransferase activity | Rattus norvegicus | 3D-structure Acetylation Direct protein sequencing Methyltransferase Phosphoprotein Reference proteome S-adenosyl-L-methionine Transferase | MSSSAASPLF | MSSSAASPLFAPGEDCGPAWRAAPAAYDTSDTHLQILGKPVMERWETPYMHSLAAAAASRGGRVLEVGFGMAIAASRVQQAPIKEHWIIECNDGVFQRLQNWALKQPHKVVPLKGLWEEEAPTLPDGHFDGILYDTYPLSEETWHTHQFNFIKTHAFRLLKPGGILTYCNLTSWGELMKSKYTDITAMFEETQVPALLEAGFQRENICTEVMALVPPADCRYYAFPQMITPLVTKH | animal organ morphogenesis creatine biosynthetic process embryonic liver development methylation regulation of multicellular organism growth S-adenosylhomocysteine metabolic process S-adenosylmethionine metabolic process spermatogenesis cytoplasm; nucleus guanidinoacetate N-methyltransferase activity identical protein ... |
carbohydrate transport fructose transmembrane transport glucose mediated signaling pathway glucose transmembrane transport mannose transmembrane transport negative regulation of meiotic nuclear division | cell periphery; membrane; plasma membrane | carbohydrate:proton symporter activity glucose binding | Saccharomyces cerevisiae | Cell membrane Glycoprotein Membrane Reference proteome Sugar transport Transmembrane Transmembrane helix Transport | MDPNSNSSSE | MDPNSNSSSETLRQEKQGFLDKALQRVKGIALRRNNSNKDHTTDDTTGSIRTPTSLQRQNSDRQSNMTSVFTDDISTIDDNSILFSEPPQKQSMMMSICVGVFVAVGGFLFGYDTGLINSITSMNYVKSHVAPNHDSFTAQQMSILVSFLSLGTFFGALTAPFISDSYGRKPTIIFSTIFIFSIGNSLQVGAGGITLLIVGRVISGIGIGAISAVVPLYQAEATHKSLRGAIISTYQWAITWGLLVSSAVSQGTHARNDASSYRIPIGLQYVWSSFLAIGMFFLPESPRYYVLKDKLDEAAKSLSFLRGVPVHDSGLLEE... | carbohydrate transport fructose transmembrane transport glucose mediated signaling pathway glucose transmembrane transport mannose transmembrane transport negative regulation of meiotic nuclear division cell periphery; membrane; plasma membrane carbohydrate:proton symporter activity glucose binding Saccharomyces cerevi... |
amino acid biosynthetic process aromatic amino acid family biosynthetic process chorismate biosynthetic process phosphorylation | cytoplasm | ATP binding magnesium ion binding shikimate kinase activity | Dickeya chrysanthemi | 3D-structure Amino-acid biosynthesis Aromatic amino acid biosynthesis ATP-binding Cytoplasm Kinase Magnesium Metal-binding Nucleotide-binding Transferase | MTEPIFMVGA | MTEPIFMVGARGCGKTTVGRELARALGYEFVDTDIFMQHTSGMTVADVVAAEGWPGFRRRESEALQAVATPNRVVATGGGMVLLEQNRQFMRAHGTVVYLFAPAEELALRLQASPQAHQRPTLTGRPIAEEMEAVLREREALYQDVAHYVVDATQPPAAIVCELMQTMRLPAA | amino acid biosynthetic process aromatic amino acid family biosynthetic process chorismate biosynthetic process phosphorylation cytoplasm ATP binding magnesium ion binding shikimate kinase activity Dickeya chrysanthemi 3D-structure Amino-acid biosynthesis Aromatic amino acid biosynthesis ATP-binding Cytoplasm Kinase M... |
antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to interleukin-1 cellular response to lipopolysaccharide chemokine-mediated signaling pathway inflammatory response leukocyte chemotaxis neutrophil chemotaxis positive regulation of cytosolic calcium ion concentration response to ... | extracellular space | chemokine activity CXCR chemokine receptor binding | Mus musculus | 3D-structure Chemotaxis Cytokine Direct protein sequencing Disulfide bond Inflammatory response Reference proteome Secreted Signal | MAPPTCRLLS | MAPPTCRLLSAALVLLLLLATNHQATGAVVASELRCQCLKTLPRVDFKNIQSLSVTPPGPHCAQTEVIATLKGGQKVCLDPEAPLVQKIIQKILNKGKAN | antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to interleukin-1 cellular response to lipopolysaccharide chemokine-mediated signaling pathway inflammatory response leukocyte chemotaxis neutrophil chemotaxis positive regulation of cytosolic calcium ion concentration response to ... |
leaf senescence response to cold response to jasmonic acid response to light stimulus | apoplast; chloroplast; chloroplast envelope; chloroplast stroma; chloroplast thylakoid membrane; Golgi apparatus; nucleus; plant-type cell wall; plastoglobule; stromule; thylakoid | ADP binding ATP binding ATP hydrolysis activity enzyme regulator activity mRNA binding ribulose-1,5-bisphosphate carboxylase/oxygenase activator activity | Arabidopsis thaliana | 3D-structure Alternative splicing ATP-binding Chloroplast Nucleotide-binding Phosphoprotein Plastid Reference proteome Transit peptide | MAAAVSTVGA | MAAAVSTVGAINRAPLSLNGSGSGAVSAPASTFLGKKVVTVSRFAQSNKKSNGSFKVLAVKEDKQTDGDRWRGLAYDTSDDQQDITRGKGMVDSVFQAPMGTGTHHAVLSSYEYVSQGLRQYNLDNMMDGFYIAPAFMDKLVVHITKNFLTLPNIKVPLILGIWGGKGQGKSFQCELVMAKMGINPIMMSAGELESGNAGEPAKLIRQRYREAADLIKKGKMCCLFINDLDAGAGRMGGTTQYTVNNQMVNATLMNIADNPTNVQLPGMYNKEENARVPIICTGNDFSTLYAPLIRDGRMEKFYWAPTREDRIGVCKGIF... | leaf senescence response to cold response to jasmonic acid response to light stimulus apoplast; chloroplast; chloroplast envelope; chloroplast stroma; chloroplast thylakoid membrane; Golgi apparatus; nucleus; plant-type cell wall; plastoglobule; stromule; thylakoid ADP binding ATP binding ATP hydrolysis activity enzyme... |
ascorbate homeostasis | chromaffin granule membrane; lysosomal membrane | metal ion binding oxidoreductase activity transmembrane monodehydroascorbate reductase activity | Bos taurus | Acetylation Cytoplasmic vesicle Direct protein sequencing Electron transport Heme Iron Membrane Metal-binding Phosphoprotein Reference proteome Translocase Transmembrane Transmembrane helix Transport | MEGPASPARA | MEGPASPARAPGALPYYVAFSQLLGLIVVAMTGAWLGMYRGGIAWESALQFNVHPLCMIIGLVFLQGDALLVYRVFRNEAKRTTKVLHGLLHVFAFVIALVGLVAVFEHHRKKGYADLYSLHSWCGILVFALFFAQWLVGFSFFLFPGASFSLRSRYRPQHVFFGAAIFLLSVATALLGLKEALLFELGTKYSMFEPEGVLANVLGLLLATFATVILYILTRADWKRPLQAEEQALSMDFKTLTEGDSPSSQ | ascorbate homeostasis chromaffin granule membrane; lysosomal membrane metal ion binding oxidoreductase activity transmembrane monodehydroascorbate reductase activity Bos taurus Acetylation Cytoplasmic vesicle Direct protein sequencing Electron transport Heme Iron Membrane Metal-binding Phosphoprotein Reference proteome... |
de novo' NAD biosynthetic process from aspartate | cytosol | flavin adenine dinucleotide binding L-aspartate oxidase activity L-aspartate:fumarate oxidoreductase activity | Escherichia coli | 3D-structure Cytoplasm Direct protein sequencing FAD Flavoprotein Nucleotide-binding Oxidoreductase Pyridine nucleotide biosynthesis Reference proteome | MNTLPEHSCD | MNTLPEHSCDVLIIGSGAAGLSLALRLADQHQVIVLSKGPVTEGSTFYAQGGIAAVFDETDSIDSHVEDTLIAGAGICDRHAVEFVASNARSCVQWLIDQGVLFDTHIQPNGEESYHLTREGGHSHRRILHAADATGREVETTLVSKALNHPNIRVLERSNAVDLIVSDKIGLPGTRRVVGAWVWNRNKETVETCHAKAVVLATGGASKVYQYTTNPDISSGDGIAMAWRAGCRVANLEFNQFHPTALYHPQARNFLLTEALRGEGAYLKRPDGTRFMPDFDERGELAPRDIVARAIDHEMKRLGADCMFLDISHKPADF... | de novo' NAD biosynthetic process from aspartate cytosol flavin adenine dinucleotide binding L-aspartate oxidase activity L-aspartate:fumarate oxidoreductase activity Escherichia coli 3D-structure Cytoplasm Direct protein sequencing FAD Flavoprotein Nucleotide-binding Oxidoreductase Pyridine nucleotide biosynthesis Ref... |
nitrate assimilation nitrate catabolic process nitrate transmembrane transport nitrite transport | plasma membrane | nitrate transmembrane transporter activity nitrite transmembrane transporter activity solute:inorganic anion antiporter activity | Escherichia coli | 3D-structure Cell inner membrane Cell membrane Membrane Nitrate assimilation Reference proteome Transmembrane Transmembrane helix Transport | MSHSSAPERA | MSHSSAPERATGAVITDWRPEDPAFWQQRGQRIASRNLWISVPCLLLAFCVWMLFSAVAVNLPKVGFNFTTDQLFMLTALPSVSGALLRVPYSFMVPIFGGRRWTAFSTGILIIPCVWLGFAVQDTSTPYSVFIIISLLCGFAGANFASSMANISFFFPKQKQGGALGLNGGLGNMGVSVMQLVAPLVVSLSIFAVFGSQGVKQPDGTELYLANASWIWVPFLAIFTIAAWFGMNDLATSKASIKEQLPVLKRGHLWIMSLLYLATFGSFIGFSAGFAMLSKTQFPDVQILQYAFFGPFIGALARSAGGALSDRLGGTRV... | nitrate assimilation nitrate catabolic process nitrate transmembrane transport nitrite transport plasma membrane nitrate transmembrane transporter activity nitrite transmembrane transporter activity solute:inorganic anion antiporter activity Escherichia coli 3D-structure Cell inner membrane Cell membrane Membrane Nitra... |
glycerol-3-phosphate transmembrane transport glycerophosphodiester transmembrane transport | ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; glycerol-3-phosphate-transporting ATPase complex; membrane; plasma membrane | glycerol-3-phosphate transmembrane transporter activity glycerophosphodiester transmembrane transporter activity | Escherichia coli | Cell inner membrane Cell membrane Membrane Reference proteome Transmembrane Transmembrane helix Transport | MSSSRPVFRS | MSSSRPVFRSRWLPYLLVAPQLIITVIFFIWPAGEALWYSLQSVDPFGFSSQFVGLDNFVTLFHDSYYLDSFWTTIKFSTFVTVSGLLVSLFFAALVEYIVRGSRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAEFGYDWNHAQNSGQAMFLVVFASVWKQISYNFLFFYAALQSIPRSLIEAAAIDGAGPIRRFFKIALPLIAPVSFFLLVVNLVYAFFDTFPVIDAATSGGPVQATTTLIYKIYREGFTGLDLASSAAQSVVLMFLVIVLTVVQFRYVESKVRYQ | glycerol-3-phosphate transmembrane transport glycerophosphodiester transmembrane transport ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; glycerol-3-phosphate-transporting ATPase complex; membrane; plasma membrane glycerol-3-phosphate transmembrane transporter activity glycerophos... |
glycerol-3-phosphate transmembrane transport | ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; glycerol-3-phosphate-transporting ATPase complex; membrane; plasma membrane | glycerol-3-phosphate transmembrane transporter activity | Escherichia coli | Cell inner membrane Cell membrane Membrane Reference proteome Transmembrane Transmembrane helix Transport | MIENRPWLTI | MIENRPWLTIFSHTMLILGIAVILFPLYVAFVAATLDKQAVYAAPMTLIPGTHLLENIHNIWVNGVGTNSAPFWRMLLNSFVMAFSITLGKITVSMLSAFAIVWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLQMLDSYAGLTLPLMASATATFLFRQFFMTLPDELVEAARIDGASPMRFFCDIVFPLSKTNLAALFVITFIYGWNQYLWPLLIITDVDLGTTVAGIKGMIATGEGTTEWNSVMVAMLLTLIPPVVIVLVMQRAFVRGLVDSEK | glycerol-3-phosphate transmembrane transport ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; glycerol-3-phosphate-transporting ATPase complex; membrane; plasma membrane glycerol-3-phosphate transmembrane transporter activity Escherichia coli Cell inner membrane Cell membrane Membra... |
carbohydrate transport glycerol-3-phosphate transmembrane transport glycerophosphodiester transmembrane transport | ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; glycerol-3-phosphate-transporting ATPase complex; membrane | ABC-type glycerol-3-phosphate transporter activity ATP binding ATP hydrolysis activity glycerol-3-phosphate transmembrane transporter activity glycerophosphodiester transmembrane transporter activity | Escherichia coli | ATP-binding Cell inner membrane Cell membrane Membrane Nucleotide-binding Reference proteome Sugar transport Translocase Transport | MAGLKLQAVT | MAGLKLQAVTKSWDGKTQVIKPLTLDVADGEFIVMVGPSGCGKSTLLRMVAGLERVTEGDIWINDQRVTEMEPKDRGIAMVFQNYALYPHMSVEENMAWGLKIRGMGKQQIAERVKEAARILELDGLLKRRPRELSGGQRQRVAMGRAIVRDPAVFLFDEPLSNLDAKLRVQMRLELQQLHRRLKTTSLYVTHDQVEAMTLAQRVMVMNGGVAEQIGTPVEVYEKPASLFVASFIGSPAMNLLTGRVNNEGTHFELDGGIELPLNGGYRQYAGRKMTLGIRPEHIALSSQAEGGVPMVMDTLEILGADNLAHGRWGEQKL... | carbohydrate transport glycerol-3-phosphate transmembrane transport glycerophosphodiester transmembrane transport ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; glycerol-3-phosphate-transporting ATPase complex; membrane ABC-type glycerol-3-phosphate transporter activity ATP bindin... |
glycerol metabolic process lipid metabolic process | cytoplasm | glycerophosphocholine phosphodiesterase activity glycerophosphodiester phosphodiesterase activity glycerophosphoinositol glycerophosphodiesterase activity magnesium ion binding | Escherichia coli | Cobalt Cytoplasm Glycerol metabolism Hydrolase Magnesium Manganese Metal-binding Reference proteome | MSNWPYPRIV | MSNWPYPRIVAHRGGGKLAPENTLASIDVGAKYGHKMIEFDAKLSKDGEIFLLHDDNLERTSNGWGVAGELNWQDLLRVDAGSWYSKMFKGEPLPLLSQVAERCREHGMMANIEIKPTTGTGPLTGKMVALAARELWAGMTPPLLSSFEIDALEAAQQAAPELPRGLLLDEWRDDWRELTARLGCVSIHLNHKLLNKARVMQLKDAGLRILVYTVNKPQRAAELLRWGVDCICTDAIDVIGPNFTAQ | glycerol metabolic process lipid metabolic process cytoplasm glycerophosphocholine phosphodiesterase activity glycerophosphodiester phosphodiesterase activity glycerophosphoinositol glycerophosphodiesterase activity magnesium ion binding Escherichia coli Cobalt Cytoplasm Glycerol metabolism Hydrolase Magnesium Manganes... |
cellular response to leukemia inhibitory factor dendrite development intracellular signal transduction negative regulation of axonogenesis regulation of small GTPase mediated signal transduction | cytoplasm; cytoskeleton; cytosol; extrinsic component of membrane; membrane | guanyl-nucleotide exchange factor activity | Homo sapiens | Alternative splicing Cytoplasm Guanine-nucleotide releasing factor Membrane Phosphoprotein Proto-oncogene Reference proteome | MAEANPRRGK | MAEANPRRGKMRFRRNAASFPGNLHLVLVLRPTSFLQRTFTDIGFWFSQEDFMLKLPVVMLSSVSDLLTYIDDKQLTPELGGTLQYCHSEWIIFRNAIENFALTVKEMAQMLQSFGTELAETELPDDIPSIEEILAIRAERYHLLKNDITAVTKEGKILLTNLEVPDTEGAVSSRLECHRQISGDWQTINKLLTQVHDMETAFDGFWEKHQLKMEQYLQLWKFEQDFQQLVTEVEFLLNQQAELADVTGTIAQVKQKIKKLENLDENSQELLSKAQFVILHGHKLAANHHYALDLICQRCNELRYLSDILVNEIKAKRIQ... | cellular response to leukemia inhibitory factor dendrite development intracellular signal transduction negative regulation of axonogenesis regulation of small GTPase mediated signal transduction cytoplasm; cytoskeleton; cytosol; extrinsic component of membrane; membrane guanyl-nucleotide exchange factor activity Homo s... |
cartilage development involved in endochondral bone morphogenesis cellular response to hormone stimulus cellular response to insulin stimulus cytokine-mediated signaling pathway endocytosis growth hormone receptor signaling pathway hormone metabolic process hormone-mediated signaling pathway insulin-like growth factor ... | cell surface; cytoplasmic ribonucleoprotein granule; cytosol; external side of plasma membrane; extracellular region; extracellular space; growth hormone receptor complex; membrane; neuronal cell body; plasma membrane; receptor complex | cytokine binding growth factor binding growth hormone receptor activity identical protein binding lipid binding peptide hormone binding proline-rich region binding protein homodimerization activity protein kinase binding protein phosphatase binding SH2 domain binding | Homo sapiens | 3D-structure Alternative splicing Cell membrane Direct protein sequencing Disease variant Disulfide bond Dwarfism Endocytosis Glycoprotein Membrane Phosphoprotein Receptor Reference proteome Secreted Signal Transmembrane Transmembrane helix Ubl conjugation | MDLWQLLLTL | MDLWQLLLTLALAGSSDAFSGSEATAAILSRAPWSLQSVNPGLKTNSSKEPKFTKCRSPERETFSCHWTDEVHHGTKNLGPIQLFYTRRNTQEWTQEWKECPDYVSAGENSCYFNSSFTSIWIPYCIKLTSNGGTVDEKCFSVDEIVQPDPPIALNWTLLNVSLTGIHADIQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDPILTTSVPVYSLKVDKEYEVRVRSKQRNSGNYGEFSEVLYVTLPQMSQFTCEEDFYFPWLLIIIFGIFGLTVMLFVFLFSKQQRIKMLILPPVPVPKIKGIDPDLLKEGKLE... | cartilage development involved in endochondral bone morphogenesis cellular response to hormone stimulus cellular response to insulin stimulus cytokine-mediated signaling pathway endocytosis growth hormone receptor signaling pathway hormone metabolic process hormone-mediated signaling pathway insulin-like growth factor ... |
apoptotic process CD8-positive, alpha-beta T cell differentiation cellular response to interferon-beta cellular response to mechanical stimulus defense response to virus immune system process negative regulation of cell population proliferation negative regulation of DNA-templated transcription negative regulation of r... | chromatin; cytoplasm; cytosol; nucleoplasm; nucleus | DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription c... | Homo sapiens | Acetylation Activator Antiviral defense Cytoplasm Disease variant DNA-binding Immunity Innate immunity Isopeptide bond Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation Tumor suppressor Ubl conjugation | MPITRMRMRP | MPITRMRMRPWLEMQINSNQIPGLIWINKEEMIFQIPWKHAAKHGWDINKDACLFRSWAIHTGRYKAGEKEPDPKTWKANFRCAMNSLPDIEEVKDQSRNKGSSAVRVYRMLPPLTKNQRKERKSKSSRDAKSKAKRKSCGDSSPDTFSDGLSSSTLPDDHSSYTVPGYMQDLEVEQALTPALSPCAVSSTLPDWHIPVEVVPDSTSDLYNFQVSPMPSTSEATTDEDEEGKLPEDIMKLLEQSEWQPTNVDGKGYLLNEPGVQPTSVYGDFSCKEEPEIDSPGGDIGLSLQRVFTDLKNMDATWLDSLLTPVRLPSIQA... | apoptotic process CD8-positive, alpha-beta T cell differentiation cellular response to interferon-beta cellular response to mechanical stimulus defense response to virus immune system process negative regulation of cell population proliferation negative regulation of DNA-templated transcription negative regulation of r... |
cell adhesion central nervous system development glial cell differentiation positive regulation of neuroblast proliferation skeletal system development | collagen-containing extracellular matrix; extracellular matrix; extracellular region; extracellular space; perineuronal net; synapse | hyaluronic acid binding | Homo sapiens | Disulfide bond Extracellular matrix Glycoprotein Hyaluronic acid Immunoglobulin domain Reference proteome Repeat Secreted | MKSLLLLVLI | MKSLLLLVLISICWADHLSDNYTLDHDRAIHIQAENGPHLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAFGSGIHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYQGRVFLKGGSDSDASLVITDLTLEDYGRYKCEVIEGLEDDTVVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKILGYDRCDAGWLADGSVRYPISR... | cell adhesion central nervous system development glial cell differentiation positive regulation of neuroblast proliferation skeletal system development collagen-containing extracellular matrix; extracellular matrix; extracellular region; extracellular space; perineuronal net; synapse hyaluronic acid binding Homo sapien... |
cardiac muscle contraction cardiac myofibril assembly heart contraction heart development muscle cell fate specification negative regulation of cell growth positive regulation of the force of heart contraction regulation of striated muscle contraction regulation of the force of heart contraction ventricular cardiac mus... | A band; cardiac myofibril; cytoplasm; cytoskeleton; cytosol; myofibril; myosin complex; sarcomere | actin monomer binding calcium ion binding myosin heavy chain binding structural constituent of muscle | Homo sapiens | 3D-structure Calcium Cardiomyopathy Cytoplasm Direct protein sequencing Disease variant Metal-binding Methylation Motor protein Muscle protein Myofibrillar myopathy Myosin Phosphoprotein Reference proteome Repeat | MAPKKAKKRA | MAPKKAKKRAGGANSNVFSMFEQTQIQEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRVNVKNEEIDEMIKEAPGPINFTVFLTMFGEKLKGADPEETILNAFKVFDPEGKGVLKADYVREMLTTQAERFSKEEVDQMFAAFPPDVTGNLDYKNLVHIITHGEEKD | cardiac muscle contraction cardiac myofibril assembly heart contraction heart development muscle cell fate specification negative regulation of cell growth positive regulation of the force of heart contraction regulation of striated muscle contraction regulation of the force of heart contraction ventricular cardiac mus... |
protein complex oligomerization suppression by virus of host autophagy virus-mediated pore formation in host cell membrane | host cell plasma membrane; membrane; virion membrane | monoatomic ion channel activity proton transmembrane transporter activity | Influenza A virus | Alternative splicing Disulfide bond Glycoprotein Host cell membrane Host membrane Host-virus interaction Hydrogen ion transport Inhibition of host autophagy by virus Ion channel Ion transport Lipoprotein Membrane Palmitate Phosphoprotein Signal-anchor Transmembrane Transmembrane helix Transport Viral ion channel Virion | MSLLTEVETP | MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGILHLILWILDRLFFKCIYRFFKHGLKRGPSTEGVPESMREEYRKEQQSAVDADDSHFVSIELE | protein complex oligomerization suppression by virus of host autophagy virus-mediated pore formation in host cell membrane host cell plasma membrane; membrane; virion membrane monoatomic ion channel activity proton transmembrane transporter activity Influenza A virus Alternative splicing Disulfide bond Glycoprotein Hos... |
protein complex oligomerization suppression by virus of host autophagy virus-mediated pore formation in host cell membrane | host cell plasma membrane; membrane; virion membrane | monoatomic ion channel activity proton transmembrane transporter activity | Influenza A virus | Alternative splicing Disulfide bond Glycoprotein Host cell membrane Host membrane Host-virus interaction Hydrogen ion transport Inhibition of host autophagy by virus Ion channel Ion transport Lipoprotein Membrane Palmitate Phosphoprotein Signal-anchor Transmembrane Transmembrane helix Transport Viral ion channel Virion | MSLLTEVETP | MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGILHLILWILDRLFFKCIYRLFKHGLKRGPSTEGVPESMREEYRKEQQSAVDADDSHFVNIELE | protein complex oligomerization suppression by virus of host autophagy virus-mediated pore formation in host cell membrane host cell plasma membrane; membrane; virion membrane monoatomic ion channel activity proton transmembrane transporter activity Influenza A virus Alternative splicing Disulfide bond Glycoprotein Hos... |
chromosome condensation heterochromatin formation negative regulation of DNA recombination nucleosome assembly | actin cytoskeleton; chromatin; euchromatin; Golgi apparatus; nuclear body; nucleoplasm; nucleosome; nucleus; transcription repressor complex | chromatin DNA binding DNA binding double-stranded DNA binding minor groove of adenine-thymine-rich DNA binding nucleosomal DNA binding structural constituent of chromatin | Mus musculus | Acetylation ADP-ribosylation Chromosome Citrullination DNA-binding Nucleus Reference proteome | MTENSTSAPA | MTENSTSAPAAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKGDEPKRSVAFKKTKKEVKKVATPKKAAKPKKAASKAPSKKPKATPVKKAKKKPAATPKKAKKPKVVKVKPVKASKPKKAKTVKPKAKSSAKRASKKK | chromosome condensation heterochromatin formation negative regulation of DNA recombination nucleosome assembly actin cytoskeleton; chromatin; euchromatin; Golgi apparatus; nuclear body; nucleoplasm; nucleosome; nucleus; transcription repressor complex chromatin DNA binding DNA binding double-stranded DNA binding minor ... |
androgen catabolic process bone mineralization calcium ion homeostasis cell adhesion cellular response to fluid shear stress cellular response to leukemia inhibitory factor cellular response to testosterone stimulus collecting duct development intracellular calcium ion homeostasis intracellular chloride ion homeostasis... | apical part of cell; cell projection; cytoplasm; extracellular region; extracellular space; Golgi apparatus; perinuclear region of cytoplasm; vesicle | cytokine activity extracellular matrix binding integrin binding ion binding small molecule binding | Mus musculus | Biomineralization Cell adhesion Cytokine Direct protein sequencing Glycoprotein Phosphoprotein Proteoglycan Reference proteome Secreted Sialic acid Signal | MRLAVICFCL | MRLAVICFCLFGIASSLPVKVTDSGSSEEKLYSLHPDPIATWLVPDPSQKQNLLAPQNAVSSEEKDDFKQETLPSNSNESHDHMDDDDDDDDDDGDHAESEDSVDSDESDESHHSDESDETVTASTQADTFTPIVPTVDVPNGRGDSLAYGLRSKSRSFQVSDEQYPDATDEDLTSHMKSGESKESLDVIPVAQLLSMPSDQDNNGKGSHESSQLDEPSLETHRLEHSKESQESADQSDVIDSQASSKASLEHQSHKFHSHKDKLVLDPKSKEDDRYLKFRISHELESSSSEVN | androgen catabolic process bone mineralization calcium ion homeostasis cell adhesion cellular response to fluid shear stress cellular response to leukemia inhibitory factor cellular response to testosterone stimulus collecting duct development intracellular calcium ion homeostasis intracellular chloride ion homeostasis... |
photosynthesis | chloroplast stroma; chloroplast thylakoid membrane | ferredoxin-NADP+ reductase activity | Pisum sativum | 3D-structure Chloroplast Electron transport FAD Flavoprotein Membrane NADP Oxidoreductase Photosynthesis Plastid Thylakoid Transit peptide Transport | MAAAVTAAVS | MAAAVTAAVSLPYSNSTSLPIRTSIVAPERLVFKKVSLNNVSISGRVGTIRAQVTTEAPAKVVKHSKKQDENIVVNKFKPKEPYVGRCLLNTKITGDDAPGETWHMVFSTEGEVPYREGQSIGIVPDGIDKNGKPHKLRLYSIASSAIGDFGDSKTVSLCVKRLVYTNDAGEVVKGVCSNFLCDLKPGSEVKITGPVGKEMLMPKDPNATVIMLGTGTGIAPFRSFLWKMFFEKHEDYQFNGLAWLFLGVPTSSSLLYKEEFEKMKEKAPENFRLDFAVSREQVNDKGEKMYIQTRMAQYAEELWELLKKDNTFVYMCGL... | photosynthesis chloroplast stroma; chloroplast thylakoid membrane ferredoxin-NADP+ reductase activity Pisum sativum 3D-structure Chloroplast Electron transport FAD Flavoprotein Membrane NADP Oxidoreductase Photosynthesis Plastid Thylakoid Transit peptide Transport MAAAVTAAVS MAAAVTAAVSLPYSNSTSLPIRTSIVAPERLVFKKVSLNNVSI... |
adrenal gland development cellular response to dexamethasone stimulus cellular response to growth factor stimulus cellular response to peptide hormone stimulus epinephrine biosynthetic process methylation norepinephrine metabolic process response to activity response to ethanol response to ether response to hypoxia res... | axon; cytosol; dendrite; neuronal cell body; perikaryon; terminal bouton; varicosity | methyltransferase activity phenylethanolamine N-methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity transferase activity | Rattus norvegicus | Catecholamine biosynthesis Methyltransferase Reference proteome S-adenosyl-L-methionine Transferase | MDRGSDPKHT | MDRGSDPKHTAGMDSDSDPGQAEVALAYQRFEPRAYLRNNYAPPRGDLSNPDGVGPWKLRCMAQVFATGEVSGQVLIDIGSGPTIYQLLSACAHFEDITMTDFLEVNRQELGLWLREEPGAFDWSVYSQHVCLIEDKGESWQEKERQLRARVKRVLPIDVHKPQPLGASGLAPLPADALVSAFCLEAVSPDLPSFRQALYHITTLLRPGGNLLFIGALEESWYLAGEARLSVVPVSEEEVREALVCSGYEVRDLRTYIMPAHLRTGVDDVKGIFFAWAQKIEVQV | adrenal gland development cellular response to dexamethasone stimulus cellular response to growth factor stimulus cellular response to peptide hormone stimulus epinephrine biosynthetic process methylation norepinephrine metabolic process response to activity response to ethanol response to ether response to hypoxia res... |
epinephrine biosynthetic process methylation | cytosol | phenylethanolamine N-methyltransferase activity | Bos taurus | Catecholamine biosynthesis Direct protein sequencing Methyltransferase Phosphoprotein Reference proteome S-adenosyl-L-methionine Transferase | MSGTDRSQAA | MSGTDRSQAAGAVPDSDPGLAAVSSAYQRFEPRAYLRNNYAPPRGDLSCPDGVGPWKLRCLAQTFATGEVSGRTLIDIGSGPTIYQLLSACAHFEDITMTDFLEVNRQELRLWLREEPGAFDWSVYSQHVCLIEGKGESWQEKECQLRARVKRILPIDVHRPQPLGAGGLAPLPADALVSAFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLAVVPVREEEVREALVRTATRCGICARTPMPAHLQTGVDDVKGIFFTRAQKKVGV | epinephrine biosynthetic process methylation cytosol phenylethanolamine N-methyltransferase activity Bos taurus Catecholamine biosynthesis Direct protein sequencing Methyltransferase Phosphoprotein Reference proteome S-adenosyl-L-methionine Transferase MSGTDRSQAA MSGTDRSQAAGAVPDSDPGLAAVSSAYQRFEPRAYLRNNYAPPRGDLSCPDGVGPW... |
defense response to bacterium killing of cells of another organism | extracellular region | signaling receptor binding | Bacillus subtilis | Antibiotic Antimicrobial Bacteriocin Direct protein sequencing Lantibiotic Thioether bond | MSKFDDFDLD | MSKFDDFDLDVVKVSKQDSKITPQWKSESLCTPGCVTGALQTCFLQTLTCNCKISK | defense response to bacterium killing of cells of another organism extracellular region signaling receptor binding Bacillus subtilisAntibiotic Antimicrobial Bacteriocin Direct protein sequencing Lantibiotic Thioether bond MSKFDDFDLD MSKFDDFDLDVVKVSKQDSKITPQWKSESLCTPGCVTGALQTCFLQTLTCNCKISK |
lipid catabolic process | endoplasmic reticulum; endoplasmic reticulum lumen; lipid droplet | carboxylesterase activity carboxylic ester hydrolase activity protein homodimerization activity | Rattus norvegicus | Direct protein sequencing Disulfide bond Endoplasmic reticulum Glycoprotein Hydrolase Phosphoprotein Reference proteome Serine esterase Signal | MWLCALVWAS | MWLCALVWASLAVCPIWGHPSSPPVVDTTKGKVLGKYVSLEGFTQPVAVFLGVPFAKPPLGSLRFAPPEPAEPWSFVKNTTTYPPMCSQDGVVGKLLADMLSTGKESIPLEFSEDCLYLNIYSPADLTKNSRLPVMVWIHGGGLIIGGASPYSGLALSAHENVVVVTIQYRLGIWGLFSTGDEHSRGNWAHLDQLAALRWVQDNIANFGGNPDSVTIFGESAGGVSVSALVLSPLAKNLFHRAISESGVVLTTNLDKKNTQAVAQMIATLSGCNNTSSAAMVQCLRQKTEAELLELTVKLDNTSMSTVIDGVVLPKTPEE... | lipid catabolic process endoplasmic reticulum; endoplasmic reticulum lumen; lipid droplet carboxylesterase activity carboxylic ester hydrolase activity protein homodimerization activity Rattus norvegicus Direct protein sequencing Disulfide bond Endoplasmic reticulum Glycoprotein Hydrolase Phosphoprotein Reference prote... |
negative regulation of TORC1 signaling positive regulation of transcription by RNA polymerase II regulation of establishment of protein localization to chromosome regulation of transcription by RNA polymerase II regulation of translation in response to stress response to heat | mitochondrion; nucleus; protein-DNA complex | DNA binding DNA-binding transcription factor activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding | Saccharomyces cerevisiae | Acetylation Activator Direct protein sequencing DNA-binding Nucleus Phosphoprotein Reference proteome Stress response Transcription Transcription regulation | MNNAANTGTT | MNNAANTGTTNESNVSDAPRIEPLPSLNDDDIEKILQPNDIFTTDRTDASTTSSTAIEDIINPSLDPQSAASPVPSSSFFHDSRKPSTSTHLVRRGTPLGIYQTNLYGHNSRENTNPNSTLLSSKLLAHPPVPYGQNPDLLQHAVYRAQPSSGTTNAQPRQTTRRYQSHKSRPAFVNKLWSMLNDDSNTKLIQWAEDGKSFIVTNREEFVHQILPKYFKHSNFASFVRQLNMYGWHKVQDVKSGSIQSSSDDKWQFENENFIRGREDLLEKIIRQKGSSNNHNSPSGNGNPANGSNIPLDNAAGSNNSNNNISSSNSFFN... | negative regulation of TORC1 signaling positive regulation of transcription by RNA polymerase II regulation of establishment of protein localization to chromosome regulation of transcription by RNA polymerase II regulation of translation in response to stress response to heat mitochondrion; nucleus; protein-DNA complex... |
adaptive immune response immune response T cell activation T cell receptor signaling pathway transmembrane receptor protein tyrosine kinase signaling pathway | cell surface; early endosome membrane; extracellular region; plasma membrane; receptor complex; T cell receptor complex | coreceptor activity MHC class I protein binding | Homo sapiens | Adaptive immunity Alternative splicing Cell membrane Disulfide bond Glycoprotein Immunity Immunoglobulin domain Lipoprotein Membrane Palmitate Phosphoprotein Reference proteome Secreted Signal Transmembrane Transmembrane helix | MRPRLWLLLA | MRPRLWLLLAAQLTVLHGNSVLQQTPAYIKVQTNKMVMLSCEAKISLSNMRIYWLRQRQAPSSDSHHEFLALWDSAKGTIHGEEVEQEKIAVFRDASRFILNLTSVKPEDSGIYFCMIVGSPELTFGKGTQLSVVDFLPTTAQPTKKSTLKKRVCRLPRPETQKGPLCSPITLGLLVAGVLVLLVSLGVAIHLCCRRRRARLRFMKQFYK | adaptive immune response immune response T cell activation T cell receptor signaling pathway transmembrane receptor protein tyrosine kinase signaling pathway cell surface; early endosome membrane; extracellular region; plasma membrane; receptor complex; T cell receptor complex coreceptor activity MHC class I protein bi... |
adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway chemical synaptic transmission G protein-coupled acetylcholine receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger presynaptic modulation of chemical synaptic transm... | asymmetric synapse; axon terminus; cholinergic synapse; dendrite; glutamatergic synapse; membrane; neuronal cell body; plasma membrane; postsynaptic membrane; presynapse; presynaptic membrane; symmetric synapse; synapse | arrestin family protein binding G protein-coupled acetylcholine receptor activity G protein-coupled serotonin receptor activity | Rattus norvegicus | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Postsynaptic cell membrane Receptor Reference proteome Synapse Transducer Transmembrane Transmembrane helix | MNNSTNSSNN | MNNSTNSSNNGLAITSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKEKKEPVANQDPVSPSLVQGRIVKPNNNNMPGGDGGLEHNKIQNGKAPRDGVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLGHSRDDNS... | adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway chemical synaptic transmission G protein-coupled acetylcholine receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger presynaptic modulation of chemical synaptic transm... |
DNA repair-dependent chromatin remodeling mitotic cytokinesis | cytoplasm; cytoskeleton; NuA4 histone acetyltransferase complex | ATP binding hydrolase activity | Drosophila melanogaster | Acetylation ATP-binding Cytoplasm Cytoskeleton Hydrolase Methylation Nucleotide-binding Oxidation Reference proteome | MCDDEVAALV | MCDDEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNAPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAAASTSLEKSYELPDGQVITIGNERFRCPESLFQPSFLGMESCGIHETVYNSIMKCDVDIRKDLYANIVMSGGTTMYPGIADRMQKEITA... | DNA repair-dependent chromatin remodeling mitotic cytokinesis cytoplasm; cytoskeleton; NuA4 histone acetyltransferase complex ATP binding hydrolase activity Drosophila melanogaster Acetylation ATP-binding Cytoplasm Cytoskeleton Hydrolase Methylation Nucleotide-binding Oxidation Reference proteome MCDDEVAALV MCDDEVAALVV... |
cortical actin cytoskeleton organization embryo development ending in birth or egg hatching locomotion meiosis II cytokinesis mitotic cytokinesis | actin filament; cell cortex; cytoplasm | ATP binding hydrolase activity | Caenorhabditis elegans | Acetylation ATP-binding Cytoplasm Cytoskeleton Hydrolase Nucleotide-binding Reference proteome | MCDDDVAALV | MCDDDVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITVGNERFRCPEALFQPSFLGMESAGIHETSYNSIMKCDIDIRKDLYANTVLSGGTTMYPGIADRMQKEITA... | cortical actin cytoskeleton organization embryo development ending in birth or egg hatching locomotion meiosis II cytokinesis mitotic cytokinesis actin filament; cell cortex; cytoplasm ATP binding hydrolase activity Caenorhabditis elegansAcetylation ATP-binding Cytoplasm Cytoskeleton Hydrolase Nucleotide-binding Refere... |
chromatin remodeling maintenance of protein location in cell mitotic cytokinesis sperm individualization tube formation | brahma complex; cytoplasm; cytoskeleton; Ino80 complex | ATP binding hydrolase activity | Drosophila melanogaster | 3D-structure Acetylation ATP-binding Cytoplasm Cytoskeleton Hydrolase Methylation Nucleotide-binding Oxidation Reference proteome | MCDEEVAALV | MCDEEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMEACGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITA... | chromatin remodeling maintenance of protein location in cell mitotic cytokinesis sperm individualization tube formation brahma complex; cytoplasm; cytoskeleton; Ino80 complex ATP binding hydrolase activity Drosophila melanogaster 3D-structure Acetylation ATP-binding Cytoplasm Cytoskeleton Hydrolase Methylation Nucleoti... |
chromatin remodeling DNA repair-dependent chromatin remodeling endocytosis transcription initiation-coupled chromatin remodeling | actin cortical patch; actin filament; cell division site; cell tip; Ino80 complex; mating projection tip; mitotic actomyosin contractile ring, distal actin filament layer; mitotic actomyosin contractile ring, intermediate layer; mitotic actomyosin contractile ring, proximal layer; NuA4 histone acetyltransferase complex... | ATP binding hydrolase activity structural constituent of cytoskeleton | Schizosaccharomyces pombe | ATP-binding Cytoplasm Cytoskeleton Hydrolase Nucleotide-binding Phosphoprotein Reference proteome | MEEEIAALVI | MEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHHGIMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVNNWDDMEKIWHHTFYNELRVAPEEHPCLLTEAPLNPKSNREKMTQIIFETFNAPAFYVAIQAVLSLYASGRTTGIVLDSGDGVTHTVPIYEGYALPHAIMRLDLAGRDLTDYLMKILMERGYTFSTTAEREIVRDIKEKLCYVALDFEQELQTAAQSSSLEKSYELPDGQVITIGNERFRAPEALFQPSALGLENAGIHEATYNSIMKCDVDIRKDLYGNVVMSGGTTMYPGIADRMQKEIQAL... | chromatin remodeling DNA repair-dependent chromatin remodeling endocytosis transcription initiation-coupled chromatin remodeling actin cortical patch; actin filament; cell division site; cell tip; Ino80 complex; mating projection tip; mitotic actomyosin contractile ring, distal actin filament layer; mitotic actomyosin ... |
amylin receptor signaling pathway apoptotic process bone resorption cell-cell signaling eating behavior negative regulation of amyloid fibril formation negative regulation of bone resorption negative regulation of mitochondrion organization negative regulation of osteoclast differentiation negative regulation of protei... | extracellular region; extracellular space | amyloid-beta binding hormone activity identical protein binding lipid binding receptor ligand activity signaling receptor binding | Homo sapiens | 3D-structure Amidation Amyloid Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Hormone Reference proteome Secreted Signal | MGILKLQVFL | MGILKLQVFLIVLSVALNHLKATPIESHQVEKRKCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTYGKRNAVEVLKREPLNYLPL | amylin receptor signaling pathway apoptotic process bone resorption cell-cell signaling eating behavior negative regulation of amyloid fibril formation negative regulation of bone resorption negative regulation of mitochondrion organization negative regulation of osteoclast differentiation negative regulation of protei... |
acrosomal vesicle exocytosis axonogenesis calcium-ion regulated exocytosis evoked neurotransmitter secretion insulin secretion lung development lysosome localization maintenance of presynaptic active zone structure mitochondrion organization neuromuscular synaptic transmission plasma membrane repair positive regulation... | acrosomal vesicle; axon; cytosol; endosome; lysosome; membrane; perinuclear region of cytoplasm; plasma membrane; postsynapse; presynapse; presynaptic active zone; synaptic vesicle; synaptic vesicle membrane; terminal bouton | GTP binding GTP-dependent protein binding GTPase activity myosin V binding protein-macromolecule adaptor activity | Bos taurus | Cell membrane Cell projection Cytoplasm Cytoplasmic vesicle Direct protein sequencing Exocytosis GTP-binding Lipoprotein Lysosome Membrane Methylation Nucleotide-binding Phosphoprotein Prenylation Protein transport Reference proteome Synapse Transport | MASATDARYG | MASATDARYGQKESSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDERVVSSERGRQLADHLGFEFFEASAKDNINVKQTFERLVDVICEKMSESLDTADPAVTGAKQGPQLTDQQAPPHQDCAC | acrosomal vesicle exocytosis axonogenesis calcium-ion regulated exocytosis evoked neurotransmitter secretion insulin secretion lung development lysosome localization maintenance of presynaptic active zone structure mitochondrion organization neuromuscular synaptic transmission plasma membrane repair positive regulation... |
acyl-CoA metabolic process behavioral fear response cellular response to nutrient fatty acid metabolic process glial cell proliferation hair follicle development lateral ventricle development learning or memory long-term synaptic potentiation negative regulation of fatty acid beta-oxidation negative regulation of prote... | contractile fiber; endoplasmic reticulum; extracellular space; Golgi apparatus; protein-lipid complex; synaptic vesicle | benzodiazepine receptor binding fatty-acyl-CoA binding identical protein binding long-chain fatty acyl-CoA binding | Rattus norvegicus | Acetylation Direct protein sequencing Endoplasmic reticulum Golgi apparatus Hydroxylation Lipid-binding Phosphoprotein Reference proteome Transport | MSQADFDKAA | MSQADFDKAAEEVKRLKTQPTDEEMLFIYSHFKQATVGDVNTDRPGLLDLKGKAKWDSWNKLKGTSKENAMKTYVEKVEELKKKYGI | acyl-CoA metabolic process behavioral fear response cellular response to nutrient fatty acid metabolic process glial cell proliferation hair follicle development lateral ventricle development learning or memory long-term synaptic potentiation negative regulation of fatty acid beta-oxidation negative regulation of prote... |
negative regulation of DNA duplex unwinding negative regulation of DNA metabolic process positive regulation of transcription initiation by RNA polymerase II protein homooligomerization regulation of transcription by RNA polymerase II RNA polymerase II promoter clearance | nucleolus; nucleoplasm; nucleus; transcription regulator complex | DNA helicase activity DNA-binding transcription factor binding identical protein binding RNA polymerase II cis-regulatory region sequence-specific DNA binding single-stranded DNA binding transcription coactivator activity | Mus musculus | Acetylation Activator Direct protein sequencing DNA-binding Isopeptide bond Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Ubl conjugation | MPKSKELVSS | MPKSKELVSSSSSGSDSDSEVEKKLKRKKQAVPEKPVKKQKPGETSRALASSKQSSSSRDDNMFQIGKMRYVSVRDFKGKILIDIREYWMDSEGEMKPGRKGISLNMEQWSQLKEQISDIDDAVRKL | negative regulation of DNA duplex unwinding negative regulation of DNA metabolic process positive regulation of transcription initiation by RNA polymerase II protein homooligomerization regulation of transcription by RNA polymerase II RNA polymerase II promoter clearance nucleolus; nucleoplasm; nucleus; transcription r... |
cytotoxic T cell pyroptotic process granzyme-mediated programmed cell death signaling pathway killing of cells of another organism negative regulation of DNA binding negative regulation of endodeoxyribonuclease activity negative regulation of oxidoreductase activity positive regulation of apoptotic process protein matu... | cytoplasm; extracellular space; nucleus | protein homodimerization activity serine-type endopeptidase activity serine-type peptidase activity | Mus musculus | Alternative splicing Cytolysis Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Secreted Serine protease Signal Zymogen | MRNASGPRGP | MRNASGPRGPSLATLLFLLLIPEGGCERIIGGDTVVPHSRPYMALLKLSSNTICAGALIEKNWVLTAAHCNVGKRSKFILGAHSINKEPEQQILTVKKAFPYPCYDEYTREGDLQLVRLKKKATVNRNVAILHLPKKGDDVKPGTRCRVAGWGRFGNKSAPSETLREVNITVIDRKICNDEKHYNFHPVIGLNMICAGDLRGGKDSCNGDSGSPLLCDGILRGITSFGGEKCGDRRWPGVYTFLSDKHLNWIKKIMKGSV | cytotoxic T cell pyroptotic process granzyme-mediated programmed cell death signaling pathway killing of cells of another organism negative regulation of DNA binding negative regulation of endodeoxyribonuclease activity negative regulation of oxidoreductase activity positive regulation of apoptotic process protein matu... |
nitrate assimilation nitric oxide biosynthetic process response to herbicide response to light stimulus response to symbiotic fungus | nucleus; plant-type vacuole | FAD binding heme binding identical protein binding molybdenum ion binding molybdopterin cofactor binding mRNA binding nitrate reductase (NADH) activity nitrate reductase (NADPH) activity nitrate reductase activity | Arabidopsis thaliana | Disulfide bond FAD Flavoprotein Heme Herbicide resistance Iron Metal-binding Molybdenum NAD Nitrate assimilation Oxidoreductase Reference proteome | MAASVDNRQY | MAASVDNRQYARLEPGLNGVVRSYKPPVPGRSDSPKAHQNQTTNQTVFLKPAKVHDDDEDVSSEDENETHNSNAVYYKEMIRKSNAELEPSVLDPRDEYTADSWIERNPSMVRLTGKHPFNSEAPLNRLMHHGFITPVPLHYVRNHGHVPKAQWAEWTVEVTGFVKRPMKFTMDQLVSEFAYREFAATLVCAGNRRKEQNMVKKSKGFNWGSAGVSTSVWRGVPLCDVLRRCGIFSRKGGALNVCFEGSEDLPGGAGTAGSKYGTSIKKEYAMDPSRDIILAYMQNGEYLTPDHGFPVRIIIPGFIGGRMVKWLKRIIVT... | nitrate assimilation nitric oxide biosynthetic process response to herbicide response to light stimulus response to symbiotic fungus nucleus; plant-type vacuole FAD binding heme binding identical protein binding molybdenum ion binding molybdopterin cofactor binding mRNA binding nitrate reductase (NADH) activity nitrate... |
amino acid biosynthetic process aromatic amino acid family biosynthetic process chorismate biosynthetic process circadian rhythm green leaf volatile biosynthetic process response to herbicide | chloroplast | 3-phosphoshikimate 1-carboxyvinyltransferase activity | Petunia hybrida | Amino-acid biosynthesis Aromatic amino acid biosynthesis Chloroplast Herbicide resistance Plastid Transferase Transit peptide | MAQINNMAQG | MAQINNMAQGIQTLNPNSNFHKPQVPKSSSFLVFGSKKLKNSANSMLVLKKDSIFMQKFCSFRISASVATAQKPSEIVLQPIKEISGTVKLPGSKSLSNRILLLAALSEGTTVVDNLLSSDDIHYMLGALKTLGLHVEEDSANQRAVVEGCGGLFPVGKESKEEIQLFLGNAGTAMRPLTAAVTVAGGNSRYVLDGVPRMRERPISDLVDGLKQLGAEVDCFLGTKCPPVRIVSKGGLPGGKVKLSGSISSQYLTALLMAAPLALGDVEIEIIDKLISVPYVEMTLKLMERFGISVEHSSSWDRFFVRGGQKYKSPGKAF... | amino acid biosynthetic process aromatic amino acid family biosynthetic process chorismate biosynthetic process circadian rhythm green leaf volatile biosynthetic process response to herbicide chloroplast 3-phosphoshikimate 1-carboxyvinyltransferase activity Petunia hybrida Amino-acid biosynthesis Aromatic amino acid bi... |
nuclear envelope organization | intermediate filament; nuclear envelope; nuclear lamina; nucleoplasm | structural constituent of cytoskeleton | Xenopus laevis | Acetylation Coiled coil Intermediate filament Lipoprotein Methylation Nucleus Prenylation Reference proteome | METPGQKRAT | METPGQKRATRSTHTPLSPTRITRLQEKEDLQGLNDRLAVYIDKVRSLELENARLRLRITESEDVISREVTGIKSAYETELADARKTLDSVAKERARLQLELSKIREEHKELKARNAKKESDLLTAQARLKDLEALLNSKDAALTTALGEKRNLENEIRELKAHIAKLEASLADTKKQLQDEMLRRVDTENRNQTLKEELEFQKSIYNEEMRETKRRHETRLVEVDNGRQREFESKLADALHELRAQHEGQIGLYKEELGKTYNAKLENAKQSAERNSSLVGEAQEEIQQSRIRIDSLSAQLSQLQKQLAAREAKLRDLE... | nuclear envelope organization intermediate filament; nuclear envelope; nuclear lamina; nucleoplasm structural constituent of cytoskeleton Xenopus laevis Acetylation Coiled coil Intermediate filament Lipoprotein Methylation Nucleus Prenylation Reference proteome METPGQKRAT METPGQKRATRSTHTPLSPTRITRLQEKEDLQGLNDRLAVYIDKVRS... |
cell population proliferation cellular response to granulocyte macrophage colony-stimulating factor stimulus embryonic placenta development granulocyte-macrophage colony-stimulating factor signaling pathway immune response interferon-tau production macrophage differentiation monocyte differentiation myeloid cell differ... | extracellular space; granulocyte macrophage colony-stimulating factor receptor complex; intracellular membrane-bounded organelle | cytokine activity granulocyte macrophage colony-stimulating factor receptor binding growth factor activity | Bos taurus | Cytokine Disulfide bond Glycoprotein Growth factor Reference proteome Secreted Signal | MWLQNLLLLG | MWLQNLLLLGTVVCSFSAPTRPPNTATRPWQHVDAIKEALSLLNHSSDTDAVMNDTEVVSEKFDSQEPTCLQTRLKLYKNGLQGSLTSLMGSLTMMATHYEKHCPPTPETSCGTQFISFKNFKEDLKEFLFIIPFDCWEPAQK | cell population proliferation cellular response to granulocyte macrophage colony-stimulating factor stimulus embryonic placenta development granulocyte-macrophage colony-stimulating factor signaling pathway immune response interferon-tau production macrophage differentiation monocyte differentiation myeloid cell differ... |
glucose metabolic process glyoxylate cycle phosphorylation tricarboxylic acid cycle | cytoplasm | kinase activity AMP binding ATP binding magnesium ion binding manganese ion binding phosphoprotein phosphatase activity protein serine/threonine kinase activity protein serine/threonine phosphatase activity | Escherichia coli | 3D-structure ATP-binding Cytoplasm Direct protein sequencing Glyoxylate bypass Hydrolase Kinase Nucleotide-binding Protein phosphatase Reference proteome Serine/threonine-protein kinase Transferase Tricarboxylic acid cycle | MPRGLELLIA | MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKNRIHLYDHHVGLVVEQLRCITNGQSTDAAFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFHPDHGWESLLMRVISDLPLRLRWQNKSRDIHYIIRHLTETLGTDNLAESHLQVANELFYRNKAAWLVGKLITPSGTLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRG... | glucose metabolic process glyoxylate cycle phosphorylation tricarboxylic acid cycle cytoplasm kinase activity AMP binding ATP binding magnesium ion binding manganese ion binding phosphoprotein phosphatase activity protein serine/threonine kinase activity protein serine/threonine phosphatase activity Escherichia coli 3... |
endoplasmic reticulum to Golgi vesicle-mediated transport Golgi to plasma membrane transport Golgi vesicle transport intracellular protein transport macroautophagy vesicle-mediated transport | cytosol; Golgi apparatus; plasma membrane | GTP binding GTPase activity | Saccharomyces cerevisiae | 3D-structure ER-Golgi transport Golgi apparatus GTP-binding Hydrolase Isopeptide bond Lipoprotein Myristate Nucleotide-binding Protein transport Reference proteome Transport Ubl conjugation | MGLFASKLFS | MGLFASKLFSNLFGNKEMRILMVGLDGAGKTTVLYKLKLGEVITTIPTIGFNVETVQYKNISFTVWDVGGQDRIRSLWRHYYRNTEGVIFVVDSNDRSRIGEAREVMQRMLNEDELRNAAWLVFANKQDLPEAMSAAEITEKLGLHSIRNRPWFIQATCATSGEGLYEGLEWLSNSLKNST | endoplasmic reticulum to Golgi vesicle-mediated transport Golgi to plasma membrane transport Golgi vesicle transport intracellular protein transport macroautophagy vesicle-mediated transport cytosol; Golgi apparatus; plasma membrane GTP binding GTPase activity Saccharomyces cerevisiae 3D-structure ER-Golgi transport G... |
permeabilization of host organelle membrane involved in viral entry into host cell viral entry via permeabilization of inner membrane | host cell endoplasmic reticulum; host cell mitochondrion; host cell plasma membrane; membrane; viral capsid; viral outer capsid | host cell surface binding | Reovirus type 1 | 3D-structure Apoptosis Capsid protein Glycoprotein Host cell membrane Host endoplasmic reticulum Host membrane Host mitochondrion Lipoprotein Membrane Myristate Outer capsid protein Reference proteome Viral penetration into host cytoplasm Viral penetration via permeabilization of host membrane Virion Virus entry into h... | MGNASSIVQT | MGNASSIVQTINVTGDGNVFKPSAETSSTAVPSLSLSPGMLNPGGVPWIAIGDETSVTSPGALRRMTSKDIPETAIINTDNSSGAVPSESALVPYNDEPLVVVTEHAIANFTKAEMALEFNREFLDKLRVLSVSPKYSDLLTYVDCYVGVSARQALNNFQKQVPVITPTRQTMYVDSIQAALKALEKWEIDLRVAQTLLPTNVPIGEVSCPMQSVVKLLDDQLPDDSLIRRYPKEAAVALAKRNGGIQWMDVSEGTVMNEAVNAVAASALAPSASAPPLEEKSKLTEQAMDLVTAAEPEIIASLVPVPAPVFAIPPKPAD... | permeabilization of host organelle membrane involved in viral entry into host cell viral entry via permeabilization of inner membrane host cell endoplasmic reticulum; host cell mitochondrion; host cell plasma membrane; membrane; viral capsid; viral outer capsid host cell surface binding Reovirus type 1 3D-structure A... |
permeabilization of host organelle membrane involved in viral entry into host cell viral entry via permeabilization of inner membrane | host cell endoplasmic reticulum; host cell mitochondrion; host cell plasma membrane; membrane; viral outer capsid | host cell surface binding | Reovirus type 3 | Apoptosis Capsid protein Glycoprotein Host cell membrane Host endoplasmic reticulum Host membrane Host mitochondrion Lipoprotein Membrane Myristate Outer capsid protein Viral penetration into host cytoplasm Viral penetration via permeabilization of host membrane Virion Virus entry into host cell | MGNASSIVQT | MGNASSIVQTINVTGDGNVFKPSAETSSTAVPSLSLSPGMLNPGGVPWIAVGDETSVTSPGALRRMTSKDIPETAIINTDNSSGAVPSESALVPYIDEPLVVVTEHAITNFTKAEMALEFNREFLDKMRVLSVSPKYSDLLTYVDCYVGVSARQALNNFQKQVPVITPTRQTMYVDSIQAALKALEKWEIDLRVAQTLLPTNVPIGEVSCPMQSVVKLLDDQLPDDSLIRRYPKEAAVALAKRNGGIQWMDVSEGTVMNEAVNAVAASALAPSASAPPLEEKSKLTEQAMDLVTAAEPEIIASLAPVPAPVFAIPPKPAD... | permeabilization of host organelle membrane involved in viral entry into host cell viral entry via permeabilization of inner membrane host cell endoplasmic reticulum; host cell mitochondrion; host cell plasma membrane; membrane; viral outer capsid host cell surface binding Reovirus type 3 Apoptosis Capsid protein Gly... |
catecholamine biosynthetic process epinephrine biosynthetic process methylation | cytosol | phenylethanolamine N-methyltransferase activity | Homo sapiens | 3D-structure Catecholamine biosynthesis Direct protein sequencing Methyltransferase Phosphoprotein Reference proteome S-adenosyl-L-methionine Transferase | MSGADRSPNA | MSGADRSPNAGAAPDSAPGQAAVASAYQRFEPRAYLRNNYAPPRGDLCNPNGVGPWKLRCLAQTFATGEVSGRTLIDIGSGPTVYQLLSACSHFEDITMTDFLEVNRQELGRWLQEEPGAFNWSMYSQHACLIEGKGECWQDKERQLRARVKRVLPIDVHQPQPLGAGSPAPLPADALVSAFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLTVVPVSEEEVREALVRSGYKVRDLRTYIMPAHLQTGVDDVKGVFFAWAQKVGL | catecholamine biosynthetic process epinephrine biosynthetic process methylation cytosol phenylethanolamine N-methyltransferase activity Homo sapiens 3D-structure Catecholamine biosynthesis Direct protein sequencing Methyltransferase Phosphoprotein Reference proteome S-adenosyl-L-methionine Transferase MSGADRSPNA MSGADR... |
acrosome reaction binding of sperm to zona pellucida flagellated sperm motility penetration of zona pellucida positive regulation of protein processing sperm DNA condensation spermatogenesis | male germ cell nucleus; nucleolus; nucleosome; nucleus | DNA binding zinc ion binding | Rattus norvegicus | Chromosome Developmental protein Differentiation Direct protein sequencing DNA-binding Metal-binding Nucleosome core Nucleus Phosphoprotein Reference proteome Spermatogenesis Zinc | MDTKMQSLPT | MDTKMQSLPTTHPHPHSSSRPQSHTNNQCACSHHCRSCSQAGHPSSSSSPSPGPPTKHPKTPMHSRYSPSRPSHRGSCPKNRKTLEGKVSKRKAVRRRKRTHRAKRRSSGRRYK | acrosome reaction binding of sperm to zona pellucida flagellated sperm motility penetration of zona pellucida positive regulation of protein processing sperm DNA condensation spermatogenesis male germ cell nucleus; nucleolus; nucleosome; nucleus DNA binding zinc ion binding Rattus norvegicus Chromosome Developmental pr... |
dephosphorylation lysosome organization | extracellular exosome; lysosomal lumen; lysosomal membrane; lysosome; membrane | acid phosphatase activity | Homo sapiens | Alternative splicing Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Lysosome Membrane Reference proteome Signal Transmembrane Transmembrane helix | MAGKRSGWSR | MAGKRSGWSRAALLQLLLGVNLVVMPPTRARSLRFVTLLYRHGDRSPVKTYPKDPYQEEEWPQGFGQLTKEGMLQHWELGQALRQRYHGFLNTSYHRQEVYVRSTDFDRTLMSAEANLAGLFPPNGMQRFNPNISWQPIPVHTVPITEDRLLKFPLGPCPRYEQLQNETRQTPEYQNESSRNAQFLDMVANETGLTDLTLETVWNVYDTLFCEQTHGLRLPPWASPQTMQRLSRLKDFSFRFLFGIYQQAEKARLQGGVLLAQIRKNLTLMATTSQLPKLLVYSAHDTTLVALQMALDVYNGEQAPYASCHIFELYQEDS... | dephosphorylation lysosome organization extracellular exosome; lysosomal lumen; lysosomal membrane; lysosome; membrane acid phosphatase activity Homo sapiens Alternative splicing Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Lysosome Membrane Reference proteome Signal Transmembrane Transmembrane helix... |
DNA-templated transcription viral RNA genome replication | virion component | metal ion binding nucleotide binding RNA binding RNA uridylyltransferase activity RNA-dependent RNA polymerase activity | Pseudomonas phage phi6 | 3D-structure Direct protein sequencing Magnesium Manganese Metal-binding Nucleotide-binding Nucleotidyltransferase Reference proteome RNA-directed RNA polymerase Transferase Viral RNA replication Virion | MPRRAPAFPL | MPRRAPAFPLSDIKAQMLFANNIKAQQASKRSFKEGAIETYEGLLSVDPRFLSFKNELSRYLTDHFPANVDEYGRVYGNGVRTNFFGMRHMNGFPMIPATWPLASNLKKRADADLADGPVSERDNLLFRAAVRLMFSDLEPVPLKIRKGSSTCIPYFSNDMGTKIEIAERALEKAEEAGNLMLQGKFDDAYQLHQMGGAYYVVYRAQSTDAITLDPKTGKFVSKDRMVADFEYAVTGGEQGSLFAASKDASRLKEQYGIDVPDGFFCERRRTAMGGPFALNAPIMAVAQPVRNKIYSKYAYTFHHTTRLNKEEKVKEWSL... | DNA-templated transcription viral RNA genome replication virion component metal ion binding nucleotide binding RNA binding RNA uridylyltransferase activity RNA-dependent RNA polymerase activity Pseudomonas phage phi6 3D-structure Direct protein sequencing Magnesium Manganese Metal-binding Nucleotide-binding Nucleotidyl... |
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane viral budding from plasma membrane virion attachment to host cell | host cell plasma membrane; membrane; viral envelope; virion membrane | host cell surface receptor binding | Influenza A virus | Clathrin- and caveolin-independent endocytosis of virus by host Clathrin-mediated endocytosis of virus by host Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Hemagglutinin Host cell membrane Host membrane Host-virus interaction Lipoprotein M... | MEEIVLLFAI | MEEIVLLFAIVSLARSDQICIGYHANNSTKQVDTIMEKNVTVTHAQDILEKTHNGKLCSLNGVKPLILRDCSVAGWLLGNPMCDEFLNVPEWSYIVEKDNPVNGLCYPGDFNDYEELKHLLSCTKHFEKIRIIPRDSWPNHEASLGVSSACPYNGRSSFFRNVVWLIKKDNAYPTIKRSYNNTNKEDLLILWGIHHPNDAAEQTKLYQNPTTYVSVGTSTLNQRSIPKIATRPKLNGQSGRMEFFWTILKPSDTINFESNGNFIAPEYAYKIVKKGDSAIMKSGLEYGNCNTKCQTPIGAINSSMPFHNIHPLTIGECPK... | clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane viral budding from plasma membrane virion attachment to host cell host cell plasma membrane; membrane; viral envelope; virion membrane host cell surface receptor b... |
microtubule-based process | cytoplasm; microtubule; nucleus; plasma membrane | GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton | Arabidopsis thaliana | Cytoplasm Cytoskeleton GTP-binding Hydrolase Magnesium Metal-binding Microtubule Nucleotide-binding Phosphoprotein Reference proteome | MREIISIHIG | MREIISIHIGQAGIQVGNSCWELYCLEHGIQPDGTMPSDSTVGACHDAFNTFFSETSSGQHVPRAVFLDLEPTVIDEVRTGTYRQLFHPEQLISGKEDAANNFARGHYTVGREIVDTCLERLRKLADNCTGLQGFLVFNAVGGGTGSGLGSLLLERLSVDFGKKSKLGFTIYPSPQVSTAVVEPYNSVLSTHSLLEHTDVVVLLDNEAIYDICRRSLDIERPTYSNLNRLISQTISSLTTSLRFDGAINVDITEFQTNLVPYPRIHFMLSSYAPVISSAKAYHEQFSVPEITTSVFEPSNMMAKCDPRHGKYMACCLMYR... | microtubule-based process cytoplasm; microtubule; nucleus; plasma membrane GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton Arabidopsis thaliana Cytoplasm Cytoskeleton GTP-binding Hydrolase Magnesium Metal-binding Microtubule Nucleotide-binding Phosphoprotein Reference proteome MR... |
ATP metabolic process cellular response to starvation cellular response to steroid hormone stimulus chaperone cofactor-dependent protein refolding chaperone-mediated autophagy chaperone-mediated autophagy translocation complex disassembly clathrin coat disassembly late endosomal microautophagy membrane organization mRN... | autophagosome; blood microparticle; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane; cytoplasm; cytosol; dendrite; extracellular exosome; extracellular region; extracellular space; ficolin-1-rich granule lumen; focal adhesion; lumenal side of lysosomal membrane; lysosomal lumen; lysosomal membrane;... | ATP binding ATP hydrolysis activity ATP-dependent protein disaggregase activity ATP-dependent protein folding chaperone C3HC4-type RING finger domain binding cadherin binding clathrin-uncoating ATPase activity enzyme binding G protein-coupled receptor binding heat shock protein binding MHC class II protein complex bind... | Homo sapiens | 3D-structure Acetylation Alternative splicing ATP-binding Autophagy Cell membrane Chaperone Cytoplasm Direct protein sequencing Host-virus interaction Hydrolase Isopeptide bond Lysosome Membrane Methylation mRNA processing mRNA splicing Nucleotide-binding Nucleus Phosphoprotein Reference proteome Repressor Spliceosome ... | MSKGPAVGID | MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKA... | ATP metabolic process cellular response to starvation cellular response to steroid hormone stimulus chaperone cofactor-dependent protein refolding chaperone-mediated autophagy chaperone-mediated autophagy translocation complex disassembly clathrin coat disassembly late endosomal microautophagy membrane organization mRN... |
axon guidance axonal fasciculation cellular response to topologically incorrect protein chaperone cofactor-dependent protein refolding chaperone-mediated protein folding follicle cell of egg chamber development late endosomal microautophagy membrane bending mRNA splicing, via spliceosome nervous system development neur... | catalytic step 2 spliceosome; cytoplasm; cytosol; nucleus; perinuclear region of cytoplasm; plasma membrane; precatalytic spliceosome; presynapse | ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone heat shock protein binding protein folding chaperone protein-folding chaperone binding | Drosophila melanogaster | ATP-binding Cytoplasm Direct protein sequencing Glycoprotein Nucleotide-binding Nucleus Reference proteome Stress response | MSKAPAVGID | MSKAPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQTIFDAKRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKETAEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGERNVLIFDLGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRALRRLRTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKA... | axon guidance axonal fasciculation cellular response to topologically incorrect protein chaperone cofactor-dependent protein refolding chaperone-mediated protein folding follicle cell of egg chamber development late endosomal microautophagy membrane bending mRNA splicing, via spliceosome nervous system development neur... |
cholesterol homeostasis cholesterol metabolic process chylomicron remnant clearance fatty acid biosynthetic process high-density lipoprotein particle remodeling intermediate-density lipoprotein particle remodeling low-density lipoprotein particle remodeling phosphatidylcholine catabolic process reverse cholesterol tran... | endoplasmic reticulum lumen; extracellular region; extracellular space; high-density lipoprotein particle | 1-acyl-2-lysophosphatidylserine acylhydrolase activity apolipoprotein binding heparin binding lipoprotein lipase activity low-density lipoprotein particle binding lysophospholipase activity phosphatidyl phospholipase B activity phosphatidylserine 1-acylhydrolase activity phospholipase A1 activity phospholipase activity... | Homo sapiens | Direct protein sequencing Disease variant Glycoprotein HDL Heparin-binding Hydrolase Lipid degradation Lipid metabolism Reference proteome Secreted Signal | MDTSPLCFSI | MDTSPLCFSILLVLCIFIQSSALGQSLKPEPFGRRAQAVETNKTLHEMKTRFLLFGETNQGCQIRINHPDTLQECGFNSSLPLVMIIHGWSVDGVLENWIWQMVAALKSQPAQPVNVGLVDWITLAHDHYTIAVRNTRLVGKEVAALLRWLEESVQLSRSHVHLIGYSLGAHVSGFAGSSIGGTHKIGRITGLDAAGPLFEGSAPSNRLSPDDANFVDAIHTFTREHMGLSVGIKQPIGHYDFYPNGGSFQPGCHFLELYRHIAQHGFNAITQTIKCSHERSVHLFIDSLLHAGTQSMAYPCGDMNSFSQGLCLSCKKGR... | cholesterol homeostasis cholesterol metabolic process chylomicron remnant clearance fatty acid biosynthetic process high-density lipoprotein particle remodeling intermediate-density lipoprotein particle remodeling low-density lipoprotein particle remodeling phosphatidylcholine catabolic process reverse cholesterol tran... |
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