Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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cellular response to fatty acid cellular response to nutrient cholesterol homeostasis chylomicron remodeling fatty acid biosynthetic process low-density lipoprotein particle mediated signaling phospholipid metabolic process positive regulation of adipose tissue development positive regulation of chemokine (C-X-C motif)... | catalytic complex; cell surface; chylomicron; extracellular space; plasma membrane; very-low-density lipoprotein particle | 1-acyl-2-lysophosphatidylserine acylhydrolase activity apolipoprotein binding calcium ion binding heparan sulfate proteoglycan binding heparin binding lipoprotein lipase activity lipoprotein particle binding phosphatidylserine 1-acylhydrolase activity phospholipase A1 activity phospholipase activity protein homodimeriz... | Bos taurus | 3D-structure Calcium Cell membrane Chylomicron Direct protein sequencing Disulfide bond Extracellular matrix Glycoprotein Heparin-binding Hydrolase Lipid degradation Lipid metabolism Membrane Metal-binding Nitration Reference proteome Secreted Signal VLDL | MESKALLLLA | MESKALLLLALSVCLQSLTVSRGGLVAADRITGGKDFRDIESKFALRTPEDTAEDTCHLIPGVTESVANCHFNHSSKTFVVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLSRAQQHYPVSAGYTKLVGQDVAKFMNWMADEFNYPLGNVHLLGYSLGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGEALRVIAERGLGDVDQLVKCSHERSVHLFIDSLLNEENPSKAYRCNSKEAFEKGLCLSCRKNRCNNMGYEI... | cellular response to fatty acid cellular response to nutrient cholesterol homeostasis chylomicron remodeling fatty acid biosynthetic process low-density lipoprotein particle mediated signaling phospholipid metabolic process positive regulation of adipose tissue development positive regulation of chemokine (C-X-C motif)... |
chylomicron remodeling fatty acid metabolic process triglyceride catabolic process | chylomicron; extracellular space; plasma membrane; very-low-density lipoprotein particle | 1-acyl-2-lysophosphatidylserine acylhydrolase activity heparan sulfate proteoglycan binding heparin binding lipoprotein lipase activity lipoprotein particle binding metal ion binding phosphatidylserine 1-acylhydrolase activity phospholipase A1 activity triglyceride lipase activity | Cavia porcellus | Calcium Cell membrane Chylomicron Disulfide bond Extracellular matrix Glycoprotein Heparin-binding Hydrolase Lipid degradation Lipid metabolism Membrane Metal-binding Nitration Reference proteome Secreted Signal VLDL | MNIDRKILNK | MNIDRKILNKALAKEKVANCQKDYTDIESKFARRTPENTVEDTCHLIPGVTESVANCHFNHSSKTFMVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLRRAQHHYPESADYTKLVGEDVARFINWMEDEFKYSVDNVHLLGYSLGAHAAGVAGSRTNTKVSRITGLDPAGPNFEYAEATSRLSPDDAQFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGSFQPGCNIQDALRVISQKGFGDMDQLVKCSHERSIHLFIDSLLNEENPSKAYRCNSKEAFEKGLCLSCRKNRCNNVGYEINKVRAKRSSKMYL... | chylomicron remodeling fatty acid metabolic process triglyceride catabolic process chylomicron; extracellular space; plasma membrane; very-low-density lipoprotein particle 1-acyl-2-lysophosphatidylserine acylhydrolase activity heparan sulfate proteoglycan binding heparin binding lipoprotein lipase activity lipoprotein ... |
phosphorylation photosynthesis pyruvate metabolic process | chloroplast | ATP binding kinase activity metal ion binding pyruvate, phosphate dikinase activity | Zea mays | 3D-structure Acetylation Alternative promoter usage ATP-binding Chloroplast Cytoplasm Direct protein sequencing Kinase Magnesium Metal-binding Nucleotide-binding Phosphoprotein Photosynthesis Plastid Reference proteome Transferase Transit peptide | MAASVSRAIC | MAASVSRAICVQKPGSKCTRDREATSFARRSVAAPRPPHAKAAGVIRSDSGAGRGQHCSPLRAVVDAAPIQTTKKRVFHFGKGKSEGNKTMKELLGGKGANLAEMASIGLSVPPGFTVSTEACQQYQDAGCALPAGLWAEIVDGLQWVEEYMGATLGDPQRPLLLSVRSGAAVSMPGMMDTVLNLGLNDEVAAGLAAKSGERFAYDSFRRFLDMFGNVVMDIPRSLFEEKLEHMKESKGLKNDTDLTASDLKELVGQYKEVYLSAKGEPFPSDPKKQLELAVLAVFNSWESPRAKKYRSINQITGLRGTAVNVQCMVFGN... | phosphorylation photosynthesis pyruvate metabolic process chloroplast ATP binding kinase activity metal ion binding pyruvate, phosphate dikinase activity Zea mays 3D-structure Acetylation Alternative promoter usage ATP-binding Chloroplast Cytoplasm Direct protein sequencing Kinase Magnesium Metal-binding Nucleotide-bin... |
2'-deoxyribonucleotide biosynthetic process blastocyst development deoxyribonucleotide biosynthetic process deoxyribonucleotide metabolic process positive regulation of G1/S transition of mitotic cell cycle protein heterotetramerization ribonucleoside diphosphate metabolic process | cytosol; nuclear envelope; ribonucleoside-diphosphate reductase complex | ferric iron binding identical protein binding protein homodimerization activity ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor | Mus musculus | 3D-structure Cytoplasm Deoxyribonucleotide synthesis Iron Metal-binding Nucleus Oxidoreductase Phosphoprotein Reference proteome Ubl conjugation | MLSVRTPLAT | MLSVRTPLATIADQQQLQLSPLKRLTLADKENTPPTLSSTRVLASKAARRIFQDSAELESKAPTNPSVEDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITNAVRIEQEFLTEALPVKLIGMNCTL... | 2'-deoxyribonucleotide biosynthetic process blastocyst development deoxyribonucleotide biosynthetic process deoxyribonucleotide metabolic process positive regulation of G1/S transition of mitotic cell cycle protein heterotetramerization ribonucleoside diphosphate metabolic process cytosol; nuclear envelope; ribonucleos... |
aorta development brain development brain segmentation cellular response to organic substance facial nerve structural organization fat cell differentiation gene expression learning or memory motor neuron axon guidance myelination peripheral nervous system development positive regulation of DNA-templated transcription p... | chromatin; cytoplasm; intracellular membrane-bounded organelle; nucleoplasm; nucleus | chromatin binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific HMG box domain binding metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA po... | Homo sapiens | Acetylation Activator Alternative splicing Charcot-Marie-Tooth disease Dejerine-Sottas syndrome Disease variant DNA-binding Metal-binding Neurodegeneration Neuropathy Nucleus Reference proteome Repeat Transcription Transcription regulation Transferase Ubl conjugation Ubl conjugation pathway Zinc Zinc-finger | MMTAKAVDKI | MMTAKAVDKIPVTLSGFVHQLSDNIYPVEDLAATSVTIFPNAELGGPFDQMNGVAGDGMINIDMTGEKRSLDLPYPSSFAPVSAPRNQTFTYMGKFSIDPQYPGASCYPEGIINIVSAGILQGVTSPASTTASSSVTSASPNPLATGPLGVCTMSQTQPDLDHLYSPPPPPPPYSGCAGDLYQDPSAFLSAATTSTSSSLAYPPPPSYPSPKPATDPGLFPMIPDYPGFFPSQCQRDLHGTAGPDRKPFPCPLDTLRVPPPLTPLSTIRNFTLGGPSAGVTGPGASGGSEGPRLPGSSSAAAAAAAAAAYNPHHLPLRPI... | aorta development brain development brain segmentation cellular response to organic substance facial nerve structural organization fat cell differentiation gene expression learning or memory motor neuron axon guidance myelination peripheral nervous system development positive regulation of DNA-templated transcription p... |
cellular hyperosmotic response cellular response to glucose starvation cellular response to mechanical stimulus central nervous system development cerebral cortex development dehydroascorbic acid transport female pregnancy glucose import glucose import across plasma membrane glucose transmembrane transport L-ascorbic a... | apical plasma membrane; basolateral plasma membrane; blood microparticle; caveola; cortical actin cytoskeleton; cytosol; extracellular exosome; female germ cell nucleus; female pronucleus; glucose transporter complex; Golgi membrane; intercalated disc; melanosome; membrane; midbody; photoreceptor inner segment; plasma ... | D-glucose transmembrane transporter activity dehydroascorbic acid transmembrane transporter activity glucose transmembrane transporter activity identical protein binding kinase binding long-chain fatty acid transporter activity protein self-association xenobiotic transmembrane transporter activity | Homo sapiens | 3D-structure Acetylation Cataract Cell membrane Direct protein sequencing Disease variant Dystonia Epilepsy Glycoprotein Hereditary hemolytic anemia Intellectual disability Membrane Phosphoprotein Reference proteome Sugar transport Transmembrane Transmembrane helix Transport | MEPSSKKLTG | MEPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQPVYATIGSGIVNTAF... | cellular hyperosmotic response cellular response to glucose starvation cellular response to mechanical stimulus central nervous system development cerebral cortex development dehydroascorbic acid transport female pregnancy glucose import glucose import across plasma membrane glucose transmembrane transport L-ascorbic a... |
cellular hyperosmotic response cellular response to glucose starvation cellular response to mechanical stimulus central nervous system development cerebral cortex development dehydroascorbic acid transport female pregnancy glucose import glucose import across plasma membrane glucose transmembrane transport long-chain f... | apical plasma membrane; basolateral plasma membrane; caveola; cell-cell junction; cortical actin cytoskeleton; cytoplasm; cytosol; female germ cell nucleus; female pronucleus; glucose transporter complex; Golgi membrane; intercalated disc; membrane; membrane raft; midbody; photoreceptor inner segment; plasma membrane; ... | D-glucose transmembrane transporter activity dehydroascorbic acid transmembrane transporter activity glucose transmembrane transporter activity identical protein binding kinase binding long-chain fatty acid transporter activity protein self-association xenobiotic transmembrane transporter activity | Rattus norvegicus | Acetylation Cell membrane Glycoprotein Membrane Phosphoprotein Reference proteome Sugar transport Transmembrane Transmembrane helix Transport | MEPSSKKVTG | MEPSSKKVTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWNHRYGESIPSTTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNADLWPLLLSVIFIPALLQCILLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTRDLQEMKEEGRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQPVYATIGSGIVNTAF... | cellular hyperosmotic response cellular response to glucose starvation cellular response to mechanical stimulus central nervous system development cerebral cortex development dehydroascorbic acid transport female pregnancy glucose import glucose import across plasma membrane glucose transmembrane transport long-chain f... |
carbohydrate metabolic process dehydroascorbic acid transport fructose transmembrane transport galactose transmembrane transport glucose import glucose transmembrane transport positive regulation of insulin secretion involved in cellular response to glucose stimulus | apical plasma membrane; brush border; cell-cell junction; cytoplasm; membrane; plasma membrane | D-glucose transmembrane transporter activity dehydroascorbic acid transmembrane transporter activity fructose transmembrane transporter activity galactose transmembrane transporter activity glucose transmembrane transporter activity hexose transmembrane transporter activity | Homo sapiens | Alternative splicing Cell membrane Disease variant Glycoprotein Membrane Phosphoprotein Reference proteome Sugar transport Transmembrane Transmembrane helix Transport | MTEDKVTGTL | MTEDKVTGTLVFTVITAVLGSFQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNYVINSTDELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGDTLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPESPRYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQPILVALMLHVAQQFSGIN... | carbohydrate metabolic process dehydroascorbic acid transport fructose transmembrane transport galactose transmembrane transport glucose import glucose transmembrane transport positive regulation of insulin secretion involved in cellular response to glucose stimulus apical plasma membrane; brush border; cell-cell junct... |
carbohydrate metabolic process dehydroascorbic acid transport galactose transmembrane transport glucose import glucose import across plasma membrane glucose transmembrane transport L-ascorbic acid metabolic process transport across blood-brain barrier | aggresome; cell projection; extracellular exosome; ficolin-1-rich granule membrane; membrane; perikaryon; plasma membrane; secretory granule membrane; specific granule membrane; tertiary granule membrane | D-glucose transmembrane transporter activity dehydroascorbic acid transmembrane transporter activity galactose transmembrane transporter activity glucose binding glucose transmembrane transporter activity | Homo sapiens | 3D-structure Cell membrane Cell projection Glycoprotein Membrane Phosphoprotein Reference proteome Sugar transport Transmembrane Transmembrane helix Transport | MGTQKVTPAL | MGTQKVTPALIFAITVATIGSFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEPIYATIGAGVVNTIFTV... | carbohydrate metabolic process dehydroascorbic acid transport galactose transmembrane transport glucose import glucose import across plasma membrane glucose transmembrane transport L-ascorbic acid metabolic process transport across blood-brain barrier aggresome; cell projection; extracellular exosome; ficolin-1-rich gr... |
alpha-glucoside transport fucose transmembrane transport galactose transmembrane transport glucose transmembrane transport intestinal D-glucose absorption myo-inositol transport pentose transmembrane transport renal glucose absorption | apical plasma membrane | alpha-glucoside transmembrane transporter activity fucose transmembrane transporter activity galactose transmembrane transporter activity galactose:sodium symporter activity glucose:sodium symporter activity myo-inositol:sodium symporter activity pentose transmembrane transporter activity water transmembrane transporte... | Oryctolagus cuniculus | Cell membrane Disulfide bond Glycoprotein Ion transport Membrane Reference proteome Sodium Sodium transport Sugar transport Symport Transmembrane Transmembrane helix Transport | MDSSTLSPLT | MDSSTLSPLTTSTAAPLESYERIRNAADISVIVIYFLVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGLAGTGAASGIATGGFEWNALIMVVVLGWVFVPIYIRAGVVTMPEYLQKRFGGKRIQIYLSILSLLLYIFTKISADIFSGAIFIQLTLGLDIYVAIIILLVITGLYTITGGLAAVIYTDTLQTAIMMVGSVILTGFAFHEVGGYEAFTEKYMRAIPSQISYGNTSIPQKCYTPREDAFHIFRDAITGDIPWPGLVFGMSILTLWYWCTDQVIVQRCLSAKNLSHVKAGCILCGYL... | alpha-glucoside transport fucose transmembrane transport galactose transmembrane transport glucose transmembrane transport intestinal D-glucose absorption myo-inositol transport pentose transmembrane transport renal glucose absorption apical plasma membrane alpha-glucoside transmembrane transporter activity fucose tran... |
actin cytoskeleton organization actomyosin structure organization cell cycle cell division cortical actin cytoskeleton organization positive regulation of protein binding positive regulation of protein localization to cell cortex protein-containing complex assembly regulation of calcium ion transport regulation of inte... | basolateral plasma membrane; cell cortex; cell junction; cortical cytoskeleton; cytoplasmic side of plasma membrane; cytoskeleton; cytosol; intercellular bridge; mitotic spindle; nuclear body; plasma membrane; protein-containing complex; spectrin-associated cytoskeleton | 1-phosphatidylinositol binding actin binding calmodulin binding phosphoprotein binding spectrin binding structural constituent of cytoskeleton | Homo sapiens | 3D-structure Actin-binding Alternative splicing Calmodulin-binding Cell cycle Cell division Cytoplasm Cytoskeleton Direct protein sequencing Elliptocytosis Glycoprotein Hereditary hemolytic anemia Mitosis Nucleus Phosphoprotein Pyropoikilocytosis Reference proteome Transport | MTTEKSLVTE | MTTEKSLVTEAENSQHQQKEEGEEAINSGQQEPQQEESCQTAAEGDNWCEQKLKASNGDTPTHEDLTKNKERTSESRGLSRLFSSFLKRPKSQVSEEEGKEVESDKEKGEGGQKEIEFGTSLDEEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQEELREDPDFEIKEGEGLEECSKIEVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPC... | actin cytoskeleton organization actomyosin structure organization cell cycle cell division cortical actin cytoskeleton organization positive regulation of protein binding positive regulation of protein localization to cell cortex protein-containing complex assembly regulation of calcium ion transport regulation of inte... |
de novo' pyrimidine nucleobase biosynthetic process 'de novo' UMP biosynthetic process cellular response to xenobiotic stimulus female pregnancy lactation pyrimidine nucleobase biosynthetic process UDP biosynthetic process UMP biosynthetic process | cytoplasm; cytosol; nucleus | identical protein binding orotate phosphoribosyltransferase activity orotidine-5'-phosphate decarboxylase activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Decarboxylase Disease variant Glycosyltransferase Lyase Multifunctional enzyme Phosphoprotein Pyrimidine biosynthesis Reference proteome Transferase | MAVARAALGP | MAVARAALGPLVTGLYDVQAFKFGDFVLKSGLSSPIYIDLRGIVSRPRLLSQVADILFQTAQNAGISFDTVCGVPYTALPLATVICSTNQIPMLIRRKETKDYGTKRLVEGTINPGETCLIIEDVVTSGSSVLETVEVLQKEGLKVTDAIVLLDREQGGKDKLQAHGIRLHSVCTLSKMLEILEQQKKVDAETVGRVKRFIQENVFVAANHNGSPLSIKEAPKELSFGARAELPRIHPVASKLLRLMQKKETNLCLSADVSLARELLQLADALGPSICMLKTHVDILNDFTLDVMKELITLAKCHEFLIFEDRKFADIGN... | de novo' pyrimidine nucleobase biosynthetic process 'de novo' UMP biosynthetic process cellular response to xenobiotic stimulus female pregnancy lactation pyrimidine nucleobase biosynthetic process UDP biosynthetic process UMP biosynthetic process cytoplasm; cytosol; nucleus identical protein binding orotate phosphorib... |
acetyl-CoA biosynthetic process from pyruvate glucose metabolic process tricarboxylic acid cycle | mitochondrial matrix; mitochondrial pyruvate dehydrogenase complex; mitochondrion; nucleoplasm; nucleus; pyruvate dehydrogenase complex | pyruvate dehydrogenase (acetyl-transferring) activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Carbohydrate metabolism Direct protein sequencing Disease variant Glucose metabolism Mitochondrion Oxidoreductase Phosphoprotein Pyruvate Reference proteome Thiamine pyrophosphate Transit peptide Tricarboxylic acid cycle | MAAVSGLVRR | MAAVSGLVRRPLREVSGLLKRRFHWTAPAALQVTVRDAINQGMDEELERDEKVFLLGEEVAQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYYMSGGLQPVPIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNSEDAKGLIKSAIRDNNPVVVLENELMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLSKEGVECEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDA... | acetyl-CoA biosynthetic process from pyruvate glucose metabolic process tricarboxylic acid cycle mitochondrial matrix; mitochondrial pyruvate dehydrogenase complex; mitochondrion; nucleoplasm; nucleus; pyruvate dehydrogenase complex pyruvate dehydrogenase (acetyl-transferring) activity Homo sapiens 3D-structure Acetyla... |
2-oxoglutarate metabolic process histone succinylation L-lysine catabolic process to acetyl-CoA via saccharopine succinyl-CoA metabolic process tricarboxylic acid cycle | mitochondrial matrix; mitochondrion; nucleus; oxoglutarate dehydrogenase complex | acyltransferase activity dihydrolipoyllysine-residue succinyltransferase activity | Bos taurus | 3D-structure Acetylation Acyltransferase Direct protein sequencing Lipoyl Mitochondrion Nucleus Phosphoprotein Reference proteome Transferase Transit peptide Tricarboxylic acid cycle | MLSRSRCASR | MLSRSRCASRAFSRSLSAFQKGNCPLVRRSLPGISLCQGPGYPDSRKTVINSSNIFSVRFFRTTAVCKDDVITVKTPAFAESVTEGDVRWEKAVGDTVAEDEVVCEIETDKTSVQVPSPANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAAAPAAAAPKAEPTVSAVPPPPAAPIPTQMPPVPSPSQPLTSKPVSAVKPTAAPPRAEAGAGVGLRSEHREKMNRMRQRIAQRLKEAQNTCAMLTTFNEIDMSNIQEMRARHKDAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDATKEVVYRDYIDIS... | 2-oxoglutarate metabolic process histone succinylation L-lysine catabolic process to acetyl-CoA via saccharopine succinyl-CoA metabolic process tricarboxylic acid cycle mitochondrial matrix; mitochondrion; nucleus; oxoglutarate dehydrogenase complex acyltransferase activity dihydrolipoyllysine-residue succinyltransfera... |
glucose metabolic process tricarboxylic acid cycle | mitochondrial matrix | dihydrolipoyllysine-residue acetyltransferase activity | Bos taurus | 3D-structure Acetylation Acyltransferase Carbohydrate metabolism Direct protein sequencing Glucose metabolism Lipoyl Mitochondrion Phosphoprotein Reference proteome Repeat Transferase Transit peptide Tricarboxylic acid cycle | MWRVCARRAQ | MWRVCARRAQNAAPRAGFGARWTAFREEPGAPCVTPQAGSALARCSSKTPGYGRVRALCGWSPVSRATPRNRVLLQLWGSPSRRWYSLPPHQKVPLPSLSPTMQAGTIARWEKKEGEKINEGELIAEVETDKATVGFESVEECYMAKILVAEGTRDVPVGAIICITVDKPEDVEAFKNYTLDSSAAPAPPAAPAPTPAAPAPSPTPSAQAPGSSYPTHMQVLLPALSPTMTMGTVQRWEKKVGEKLNEGDLLAEIETDKATIGFEVQEEGYLAKILIPEGTRDVPLGTPLCIIVEKEADIPAFADYRPAEVTDLKPPAPP... | glucose metabolic process tricarboxylic acid cycle mitochondrial matrix dihydrolipoyllysine-residue acetyltransferase activity Bos taurus 3D-structure Acetylation Acyltransferase Carbohydrate metabolism Direct protein sequencing Glucose metabolism Lipoyl Mitochondrion Phosphoprotein Reference proteome Repeat Transferas... |
carboxylic acid metabolic process | cytoplasm; mitochondrial matrix; mitochondrion | acetyltransferase activity dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity lipoic acid binding | Bos taurus | 3D-structure Acetylation Acyltransferase Direct protein sequencing Lipoyl Mitochondrion Phosphoprotein Reference proteome Transferase Transit peptide | MAAALVLRTW | MAAALVLRTWSRAAGQLICVRYFQTCGNVHVLKPKYVCFFGYPPFKYSHPYQWLKTTAALQGQIVQFKLSDIGEGIREVTVKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKKLYYNLDDTAYVGKPLVDIETEALKDSEEDVVETPAVSHDEHTHQEIKGQKTLATPAVRRLAMENNIKLSEVIGSGKDGRILKEDILNYLEKQTGAILPPSPKAEIMPPPPKPKDRTIPIPISKPPVFIGKDRTEPVKGFHKAMVKTMSAALKIPHFGYCDEVDLTELVKLREELKPIAFARGIKLSFMPFFLKAASLGLL... | carboxylic acid metabolic process cytoplasm; mitochondrial matrix; mitochondrion acetyltransferase activity dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity lipoic acid binding Bos taurus 3D-structure Acetylation Acyltransferase Direct protein sequencing Lipoyl Mitochondrion Phosphoprotein Reference ... |
branched-chain amino acid catabolic process | cytoplasm; cytosol; microtubule cytoskeleton; mitochondrial alpha-ketoglutarate dehydrogenase complex; mitochondrial matrix; mitochondrial nucleoid; mitochondrion | acetyltransferase activity dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity lipoic acid binding ubiquitin protein ligase binding | Homo sapiens | 3D-structure Acetylation Acyltransferase Direct protein sequencing Disease variant Lipoyl Maple syrup urine disease Mitochondrion Phosphoprotein Reference proteome Transferase Transit peptide | MAAVRMLRTW | MAAVRMLRTWSRNAGKLICVRYFQTCGNVHVLKPNYVCFFGYPSFKYSHPHHFLKTTAALRGQVVQFKLSDIGEGIREVTVKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKKLYYNLDDIAYVGKPLVDIETEALKDSEEDVVETPAVSHDEHTHQEIKGRKTLATPAVRRLAMENNIKLSEVVGSGKDGRILKEDILNYLEKQTGAILPPSPKVEIMPPPPKPKDMTVPILVSKPPVFTGKDKTEPIKGFQKAMVKTMSAALKIPHFGYCDEIDLTELVKLREELKPIAFARGIKLSFMPFFLKAASLGLL... | branched-chain amino acid catabolic process cytoplasm; cytosol; microtubule cytoskeleton; mitochondrial alpha-ketoglutarate dehydrogenase complex; mitochondrial matrix; mitochondrial nucleoid; mitochondrion acetyltransferase activity dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity lipoic acid bindin... |
disruption by virus of host JAK-STAT cascade via inhibition of STAT1 activity disruption by virus of host JAK-STAT cascade via inhibition of STAT2 activity suppression by virus of host type I interferon-mediated signaling pathway suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signal... | host cell cytoplasm | metal ion binding RNA binding ubiquitin ligase-substrate adaptor activity | Parainfluenza virus 5 | 3D-structure Host cytoplasm Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Inhibition of host MDA5 by virus Inhibition of host RLR pathway by virus Inhibition of host STAT1 by virus Interferon antiviral system evasion Metal-binding Refe... | MDPTDLSFSP | MDPTDLSFSPDEINKLIETGLNTVEYFTSQQVTGTSSLGKNTIPPGVTGLLTNAAEAKIQESTNHQKGSVGGGAKPKKPRPKIAIVPADDKTVPGKPIPNPLLGLDSTPSTQTVLDLSGKTLPSGSYKGVKLAKFGKENLMTRFIEEPRENPIATSSPIDFKRGRDTGGFHRREYSIGWVGDEVKVTEWCNPSCSPITAAARRFECTCHQCPVTCSECERDT | disruption by virus of host JAK-STAT cascade via inhibition of STAT1 activity disruption by virus of host JAK-STAT cascade via inhibition of STAT2 activity suppression by virus of host type I interferon-mediated signaling pathway suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signal... |
negative regulation of fibrinolysis negative regulation of plasminogen activation negative regulation of proteolysis plasminogen activation platelet-derived growth factor receptor signaling pathway prevention of polyspermy proteolysis response to hypoxia smooth muscle cell migration synaptic transmission, glutamatergic... | apical part of cell; cell surface; cytoplasm; extracellular space; glutamatergic synapse; neuronal dense core vesicle; perisynaptic space; postsynapse; Schaffer collateral - CA1 synapse; secretory granule; serine protease inhibitor complex | phosphoprotein binding serine-type endopeptidase activity signaling receptor binding | Mus musculus | Cleavage on pair of basic residues Direct protein sequencing Disulfide bond EGF-like domain Glycoprotein Hydrolase Kringle Plasminogen activation Protease Reference proteome Repeat Secreted Serine protease Signal Zymogen | MKRELLCVLL | MKRELLCVLLLCGLAFPLPDQGIHGRFRRGARSYRATCRDEPTQTTYQQHQSWLRPMLRSSRVEYCRCNSGLVQCHSVPVRSCSEPRCFNGGTCQQALYFSDFVCQCPDGFVGKRCDIDTRATCFEEQGITYRGTWSTAESGAECINWNSSVLSLKPYNARRPNAIKLGLGNHNYCRNPDRDLKPWCYVFKAGKYTTEFCSTPACPKGKSEDCYVGKGVTYRGTHSLTTSQASCLPWNSIVLMGKSYTAWRTNSQALGLGRHNYCRNPDGDARPWCHVMKDRKLTWEYCDMSPCSTCGLRQYKRPQFRIKGGLYTDITSH... | negative regulation of fibrinolysis negative regulation of plasminogen activation negative regulation of proteolysis plasminogen activation platelet-derived growth factor receptor signaling pathway prevention of polyspermy proteolysis response to hypoxia smooth muscle cell migration synaptic transmission, glutamatergic... |
glycogen catabolic process | azurophil granule lumen; cytoplasm; extracellular exosome; extracellular region; membrane | glycogen phosphorylase activity linear malto-oligosaccharide phosphorylase activity pyridoxal phosphate binding SHG alpha-glucan phosphorylase activity | Homo sapiens | 3D-structure Acetylation Allosteric enzyme Carbohydrate metabolism Direct protein sequencing Glycogen metabolism Glycosyltransferase Phosphoprotein Pyridoxal phosphate Reference proteome Transferase | MAKPLTDSEK | MAKPLTDSEKRKQISVRGLAGLGDVAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQNACDEAIYQLGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYGNPWEKARPEYMLPVHFYGRVEHTPDGVKWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLQDFNVGDYIEAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCR... | glycogen catabolic process azurophil granule lumen; cytoplasm; extracellular exosome; extracellular region; membrane glycogen phosphorylase activity linear malto-oligosaccharide phosphorylase activity pyridoxal phosphate binding SHG alpha-glucan phosphorylase activity Homo sapiens 3D-structure Acetylation Allosteric en... |
glycogen catabolic process glycogen metabolic process | cytoplasm; cytosol; extracellular exosome | glycogen phosphorylase activity linear malto-oligosaccharide phosphorylase activity nucleotide binding pyridoxal phosphate binding SHG alpha-glucan phosphorylase activity | Homo sapiens | 3D-structure Acetylation Allosteric enzyme Alternative splicing Carbohydrate metabolism Disease variant Glycogen metabolism Glycogen storage disease Glycosyltransferase Nucleotide-binding Phosphoprotein Pyridoxal phosphate Reference proteome Transferase | MSRPLSDQEK | MSRPLSDQEKRKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKISGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGHVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNDFNLKDFNVGGYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCR... | glycogen catabolic process glycogen metabolic process cytoplasm; cytosol; extracellular exosome glycogen phosphorylase activity linear malto-oligosaccharide phosphorylase activity nucleotide binding pyridoxal phosphate binding SHG alpha-glucan phosphorylase activity Homo sapiens 3D-structure Acetylation Allosteric enzy... |
acute-phase response antiviral innate immune response cell surface pattern recognition receptor signaling pathway complement activation, classical pathway complement activation, lectin pathway defense response to bacterium defense response to Gram-positive bacterium innate immune response killing by host of symbiont ce... | cell surface; collagen trimer; external side of plasma membrane; extracellular region; extracellular space; multivesicular body; serine-type endopeptidase complex | calcium-dependent protein binding identical protein binding mannose binding signaling receptor binding | Homo sapiens | 3D-structure Calcium Coiled coil Collagen Complement activation lectin pathway Complement pathway Direct protein sequencing Disulfide bond Hydroxylation Immunity Innate immunity Lectin Mannose-binding Reference proteome Repeat Secreted Signal | MSLFPSLPLL | MSLFPSLPLLLLSMVAASYSETVTCEDAQKTCPAVIACSSPGINGFPGKDGRDGTKGEKGEPGQGLRGLQGPPGKLGPPGNPGPSGSPGPKGQKGDPGKSPDGDSSLAASERKALQTEMARIKKWLTFSLGKQVGNKFFLTNGEIMTFEKVKALCVKFQASVATPRNAAENGAIQNLIKEEAFLGITDEKTEGQFVDLTGNRLTYTNWNEGEPNNAGSDEDCVLLLKNGQWNDVPCSTSHLAVCEFPI | acute-phase response antiviral innate immune response cell surface pattern recognition receptor signaling pathway complement activation, classical pathway complement activation, lectin pathway defense response to bacterium defense response to Gram-positive bacterium innate immune response killing by host of symbiont ce... |
adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway chemical synaptic transmission cognition G protein-coupled acetylcholine receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messe... | axon terminus; cholinergic synapse; dendrite; glutamatergic synapse; membrane; plasma membrane; postsynaptic density membrane; presynaptic membrane; Schaffer collateral - CA1 synapse; synapse | G protein-coupled acetylcholine receptor activity G protein-coupled serotonin receptor activity phosphatidylinositol phospholipase C activity | Homo sapiens | 3D-structure Alternative splicing Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Postsynaptic cell membrane Receptor Reference proteome Synapse Transducer Transmembrane Transmembrane helix | MNTSAPPAVS | MNTSAPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQAPTKQPPR... | adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway chemical synaptic transmission cognition G protein-coupled acetylcholine receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messe... |
behavioral response to nicotine monoatomic cation transport muscle cell development muscle contraction nervous system process neuromuscular synaptic transmission postsynaptic membrane organization regulation of membrane potential signal transduction synaptic transmission, cholinergic | acetylcholine-gated channel complex; neuromuscular junction; neuron projection; plasma membrane; postsynaptic specialization membrane; synapse | acetylcholine binding acetylcholine-gated monoatomic cation-selective channel activity channel activity ligand-gated monoatomic ion channel activity transmembrane signaling receptor activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | Homo sapiens | Alternative splicing Cell membrane Congenital myasthenic syndrome Disease variant Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Phosphoprotein Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MTPGALLMLL | MTPGALLMLLGALGAPLAPGVRGSEAEGRLREKLFSGYDSSVRPAREVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLEWTDYRLSWDPAEHDGIDSLRITAESVWLPDVVLLNNNDGNFDVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVFSSYSYDSSEVSLQTGLGPDGQGHQEIHIHEGTFIENGQWEIIHKPSRLIQPPGDPRGGREGQRQEVIFYLIIRRKPLFYLVNVIAPCILITLLAIFVFYLPPDAGEKMGLSIFALLTLTVFLLLLADKVPETSLSVPIIIKYLMFTMVLVT... | behavioral response to nicotine monoatomic cation transport muscle cell development muscle contraction nervous system process neuromuscular synaptic transmission postsynaptic membrane organization regulation of membrane potential signal transduction synaptic transmission, cholinergic acetylcholine-gated channel complex... |
cell redox homeostasis cellular detoxification of hydrogen peroxide cellular response to antibiotic cellular response to glucose stimulus cellular response to hyperoxia cellular response to xenobiotic stimulus negative regulation of protein export from nucleus negative regulation of transcription by RNA polymerase II p... | axon; cytoplasm; cytosol; dendrite; extracellular region; neuronal cell body; nucleus | enzyme binding protein homodimerization activity protein-disulfide reductase (NAD(P)) activity protein-disulfide reductase activity thioredoxin-disulfide reductase (NADP) activity | Rattus norvegicus | Acetylation Activator Cytoplasm Direct protein sequencing Disulfide bond Electron transport Nucleus Redox-active center Reference proteome S-nitrosylation Secreted Transcription Transcription regulation Transport | MVKLIESKEA | MVKLIESKEAFQEALAAAGDKLVVVDFSATWCGPCKMIKPFFHSLCDKYSNVVFLEVDVDDCQDVAADCEVKCMPTFQFYKKGQKVGEFSGANKEKLEATITEFA | cell redox homeostasis cellular detoxification of hydrogen peroxide cellular response to antibiotic cellular response to glucose stimulus cellular response to hyperoxia cellular response to xenobiotic stimulus negative regulation of protein export from nucleus negative regulation of transcription by RNA polymerase II p... |
cell cycle cell division chemotaxis establishment of protein localization to mitochondrion exocytosis membrane raft localization neural tube closure positive regulation of epidermal growth factor receptor signaling pathway positive regulation of filopodium assembly positive regulation of mitochondrial fission Ras prote... | cell surface; cleavage furrow; cytoplasmic vesicle membrane; extracellular exosome; Flemming body; focal adhesion; mitochondrion; plasma membrane; Schaffer collateral - CA1 synapse; synaptic membrane | ATPase binding Edg-2 lysophosphatidic acid receptor binding G protein activity GDP binding GTP binding GTPase activity myosin binding ubiquitin protein ligase binding | Homo sapiens | 3D-structure Cell cycle Cell division Cell membrane Disease variant Exocytosis Glycoprotein GTP-binding Hydrolase Intellectual disability Lipoprotein Membrane Methylation Mitochondrion Nucleotide-binding Phosphoprotein Prenylation Reference proteome | MAANKPKGQN | MAANKPKGQNSLALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKSDLEDKRQVSVEEAKNRAEQWNVNYVETSAKTRANVDKVFFDLMREIRARKMEDSKEKNGKKKRKSLAKRIRERCCIL | cell cycle cell division chemotaxis establishment of protein localization to mitochondrion exocytosis membrane raft localization neural tube closure positive regulation of epidermal growth factor receptor signaling pathway positive regulation of filopodium assembly positive regulation of mitochondrial fission Ras prote... |
apoptotic process cell cycle cell division cellular response to exogenous dsRNA cellular response to starvation negative regulation of protein binding positive regulation of autophagosome assembly positive regulation of epidermal growth factor receptor signaling pathway positive regulation of protein binding positive r... | extracellular exosome; midbody; plasma membrane | ATPase binding G protein activity GDP binding GTP binding GTPase activity ubiquitin protein ligase binding | Homo sapiens | 3D-structure Alternative splicing Apoptosis Cell cycle Cell division Cell membrane GTP-binding Hydrolase Lipoprotein Membrane Methylation Nucleotide-binding Prenylation Reference proteome | MAANKSKGQS | MAANKSKGQSSLALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKAEEDKIPLLVVGNKSDLEERRQVPVEEARSKAEEWGVQYVETSAKTRANVDKVFFDLMREIRTKKMSENKDKNGKKSSKNKKSFKERCCLL | apoptotic process cell cycle cell division cellular response to exogenous dsRNA cellular response to starvation negative regulation of protein binding positive regulation of autophagosome assembly positive regulation of epidermal growth factor receptor signaling pathway positive regulation of protein binding positive r... |
xenobiotic metabolic process | cytosol | arylamine N-acetyltransferase activity | Homo sapiens | 3D-structure Acyltransferase Cytoplasm Direct protein sequencing Reference proteome Transferase | MDIEAYFERI | MDIEAYFERIGYKNSRNKLDLETLTDILEHQIRAVPFENLNMHCGQAMELGLEAIFDHIVRRNRGGWCLQVNQLLYWALTTIGFQTTMLGGYFYIPPVNKYSTGMVHLLLQVTIDGRNYIVDAGSGSSSQMWQPLELISGKDQPQVPCIFCLTEERGIWYLDQIRREQYITNKEFLNSHLLPKKKHQKIYLFTLEPRTIEDFESMNTYLQTSPTSSFITTSFCSLQTPEGVYCLVGFILTYRKFNYKDNTDLVEFKTLTEEEVEEVLRNIFKISLGRNLVPKPGDGSLTI | xenobiotic metabolic process cytosol arylamine N-acetyltransferase activity Homo sapiens 3D-structure Acyltransferase Cytoplasm Direct protein sequencing Reference proteome Transferase MDIEAYFERI MDIEAYFERIGYKNSRNKLDLETLTDILEHQIRAVPFENLNMHCGQAMELGLEAIFDHIVRRNRGGWCLQVNQLLYWALTTIGFQTTMLGGYFYIPPVNKYSTGMVHLLLQVTIDGRNYIVDAG... |
defense response to bacterium defense response to fungus hydrogen peroxide catabolic process hypochlorous acid biosynthetic process low-density lipoprotein particle remodeling removal of superoxide radicals respiratory burst involved in defense response response to food response to gold nanoparticle response to lipopol... | azurophil granule; extracellular space; intracellular membrane-bounded organelle; mitochondrion; nucleoplasm; secretory granule | heme binding heparin binding metal ion binding peroxidase activity | Mus musculus | Calcium Disulfide bond Glycoprotein Heme Hydrogen peroxide Iron Lysosome Metal-binding Oxidation Oxidoreductase Peroxidase Reference proteome Signal | MKLLLALAGL | MKLLLALAGLLAPLAMLQTSNGATPALLGEVENSVVLSCMEEAKQLVDRAYKERRESIKRSLQSGSASPTELLFYFKQPVAGTRTAVRAADYLHVALDLLKRKLQPLWPRPFNVTDVLTPAQLNLLSVSSGCAYQDVRVTCPPNDKYRTITGHCNNRRSPTLGASNRAFVRWLPAEYEDGVSMPFGWTPGVNRNGFKVPLARQVSNAIVRFPNDQLTKDQERALMFMQWGQFLDHDITLTPEPATRFSFFTGLNCETSCLQQPPCFPLKIPPNDPRIKNQKDCIPFFRSCPACTRNNITIRNQINALTSFVDASGVYGSE... | defense response to bacterium defense response to fungus hydrogen peroxide catabolic process hypochlorous acid biosynthetic process low-density lipoprotein particle remodeling removal of superoxide radicals respiratory burst involved in defense response response to food response to gold nanoparticle response to lipopol... |
retrotransposition | cytoplasm; cytoplasmic ribonucleoprotein granule; cytoplasmic stress granule; nucleolus; ribonucleoprotein complex | nucleotide binding single-stranded RNA binding | Mus musculus | 3D-structure Coiled coil Cytoplasm Nucleotide-binding Nucleus Reference proteome Ubl conjugation | MAKGKRKNPT | MAKGKRKNPTNRNQDHSPSSERSTPTPPSPGHPNTTENLDPDLKTFLMMMIEDIKKDFHKSLKDLQESTAKELQALKEKQENTAKQVMEMNKTILELKGEVDTIKKTQSEATLEIETLGKRSGTIDASISNRIQEMEERISGAEDSIENIDTTVKENTKCKRILTQNIQVIQDTMRRPNLRIIGIDENEDFQLKGPANIFNKIIEENFPNIKKEMPMIIQEAYRTPNRLDQKRNSSRHIIIRTTNALNKDRILKAVREKGQVTYKGRPIRITPDFSPETMKARRAWTDVIQTLREHKCQPRLLYPAKLSITIDGETKVFH... | retrotransposition cytoplasm; cytoplasmic ribonucleoprotein granule; cytoplasmic stress granule; nucleolus; ribonucleoprotein complex nucleotide binding single-stranded RNA binding Mus musculus 3D-structure Coiled coil Cytoplasm Nucleotide-binding Nucleus Reference proteome Ubl conjugation MAKGKRKNPT MAKGKRKNPTNRNQDHSP... |
membrane fusion involved in viral entry into host cell viral entry into host cell virion attachment to host cell | host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane | structural molecule activity | Simian immunodeficiency virus | Apoptosis Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Palmitate Signal Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope prot... | MGCLKNQLLI | MGCLKNQLLIAILLLSVYGIYCTQYVTVFYGVPAWRNATIPLFCATKNRDTWGTTQCLPDNGDYSELALNVTESFDAWENTVTEQAIEDVWQLFETSIKPCVKLSPLCITMRCNKSETDRWGLTKSSTTITTAAPTSAPVSEKLDMVNETSSCIAQNNCTGLEQEQMISCKFNMTGLKRDKTKEYNETWYSTDLVCEQRNSTDNESRCYMNHCNTSVIQESCDKHYWDTIRFRYCAPPGYALLRCNDTNYSGFMPKCSKVVVSSCTRMMETQTSTWFGFNGTRAENRTYIYWHGRDNRTIISLNKYYNLTMKCRRPGNKT... | membrane fusion involved in viral entry into host cell viral entry into host cell virion attachment to host cell host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane structural molecule activity Simian immunodeficiency virus Apoptosis Cleavage on pair of basic residues Coi... |
fusion of virus membrane with host plasma membrane viral entry into host cell virion attachment to host cell | host cell plasma membrane; membrane; viral envelope; virion membrane | metal ion binding | Radiation murine leukemia virus | Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host cell membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host membrane Host-virus interaction Lipoprotein Membrane Metal-binding Palmitate Signal Transmembrane Transmembrane helix Viral atta... | MESTTLSKPF | MESTTLSKPFKNQVNPWGPLIVLLILGRVNPVALGNSPHQVFNLSWEVTNEDRETVWAITGNHPLWTWWPDLTPDLCMLALHGPSYWGLEYQAPFSPPPGPPCCSGSSGSTPGCSRDCEEPLTSYTPRCNTAWNRLKLSKVTHAHNEGFYVCPGPHRPRWARSCGGPESFYCASWGCETTGRASWKPSSSWDYITVSNNLTSGQATPVCKNNTWCNSLTIRFTSLGKQATSWVTGHWWGLRLYVSGHDPGLIFGIRLKITDSGPRVPIGPNPVLSDQRPPSQPRSPPHSNSTPTETPLTLPEPPPAGVENRLLNLVKGAY... | fusion of virus membrane with host plasma membrane viral entry into host cell virion attachment to host cell host cell plasma membrane; membrane; viral envelope; virion membrane metal ion binding Radiation murine leukemia virusCleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with h... |
viral budding via host ESCRT complex | host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid | RNA binding structural constituent of virion zinc ion binding | Radiation murine leukemia virus | Capsid protein Coiled coil Direct protein sequencing Host cell membrane Host cytoplasm Host endosome Host membrane Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Phosphoprotein RNA-binding Ubl conjugation Viral budding Viral budding via the host ESCRT complexes Viral matrix protein Viral nucleoprot... | MGQTVTTPLS | MGQTVTTPLSLTLEHWGDVQRIASNQSVEVKKRRRVTFCPAEWPTFDVGWPQDGTFNLDIILQVKSKVFSPGPHGHPDQVPYIVTWEAIAYEPPSWVKPFVSPKLSLSPTAPILPSGPSTQPPPRSALYPALTPSIKPRPSKPQVLSDNGGPLIDLLTEDPPPYGEQGPSSPDGDGDREEATYTSEIPAPSPMVSRLRGKRDPPAADSTTSRAFPLRLGGNGQLQYWPFSSSDLYNWKNNNPSFSEDPGKLTALIESVLTTHQPTWDDCQQLLGTLLTGEEKQRVLLEARKAVRGNDGRPTQLPNEVNSAFPLERPDWDY... | viral budding via host ESCRT complex host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid RNA binding structural constituent of virion zinc ion binding Radiation murine leukemia virusCapsid protein Coiled coil Direct protein sequencing Host cell membrane Host cytoplasm Host endosome Host me... |
establishment of protein localization to organelle Golgi to lysosome transport granzyme-mediated programmed cell death signaling pathway lysosomal lumen acidification positive regulation of natural killer cell degranulation positive regulation of natural killer cell mediated cytotoxicity protein stabilization regulatio... | autolysosome; autophagosome membrane; azurophil granule membrane; cytolytic granule membrane; cytoplasm; cytosol; endosome membrane; external side of plasma membrane; extracellular exosome; ficolin-1-rich granule membrane; late endosome; late endosome membrane; lysosomal membrane; lysosome; melanosome; membrane; multiv... | enzyme binding ion channel inhibitor activity protein domain specific binding virus receptor activity | Homo sapiens | 3D-structure Alternative splicing Cell membrane Direct protein sequencing Disulfide bond Endosome Glycoprotein Host cell receptor for virus entry Host-virus interaction Lysosome Membrane Receptor Reference proteome Signal Transmembrane Transmembrane helix | MAAPGSARRP | MAAPGSARRPLLLLLLLLLLGLMHCASAAMFMVKNGNGTACIMANFSAAFSVNYDTKSGPKNMTFDLPSDATVVLNRSSCGKENTSDPSLVIAFGRGHTLTLNFTRNATRYSVQLMSFVYNLSDTHLFPNASSKEIKTVESITDIRADIDKKYRCVSGTQVHMNNVTVTLHDATIQAYLSNSSFSRGETRCEQDRPSPTTAPPAPPSPSPSPVPKSPSVDKYNVSGTNGTCLLASMGLQLNLTYERKDNTTVTRLLNINPNKTSASGSCGAHLVTLELHSEGTTVLLFQFGMNASSSRFFLQGIQLNTILPDARDPAFKA... | establishment of protein localization to organelle Golgi to lysosome transport granzyme-mediated programmed cell death signaling pathway lysosomal lumen acidification positive regulation of natural killer cell degranulation positive regulation of natural killer cell mediated cytotoxicity protein stabilization regulatio... |
neuropeptide signaling pathway | extracellular region | hormone activity | Neovison vison | Amidation Cleavage on pair of basic residues Endorphin Hormone Phosphoprotein Reference proteome Secreted | SEPGRREGKR | SEPGRREGKRSYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAEAFPLEFKRELAGERPEPALGPEGAAEGMAALADLEYGLVAKAEVAEKKDDGPYKMEHFRWGSPGKDKRYGGFMTSEKSQTPLVTLFKNAIIKNAHKKGQ | neuropeptide signaling pathway extracellular region hormone activity Neovison vison Amidation Cleavage on pair of basic residues Endorphin Hormone Phosphoprotein Reference proteome Secreted SEPGRREGKR SEPGRREGKRSYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAEAFPLEFKRELAGERPEPALGPEGAAEGMAALADLEYGLVAKAEVAEKKDDGPYKMEHFRWGSPGKDKRYGGFMTS... |
viral budding via host ESCRT complex | viral nucleocapsid | DNA binding nucleotide binding structural constituent of virion zinc ion binding | Mouse mammary tumor virus | 3D-structure Capsid protein Direct protein sequencing DNA-binding Host-virus interaction Lipoprotein Metal-binding Myristate Nucleotide-binding Phosphoprotein Reference proteome Repeat Ribosomal frameshifting Viral budding Viral budding via the host ESCRT complexes Viral matrix protein Viral nucleoprotein Viral release... | MGVSGSKGQK | MGVSGSKGQKLFVSVLQRLLSERGLHVKESSAIEFYQFLIKVSPWFPEEGGLNLQDWKRVGREMKKYAAEHGTDSIPKQAYPIWLQLREILTEQSDLVLLSAEAKSVTEEELEEGLTGLLSASSQEKTYGTRGTAYAEIDTEVDKLSEHIYDEPYEEKEKADKNEEKDHVRKVKKIVQRKENSEHKRKEKDQKAFLATDWNNDDLSPEDWDDLEEQAAHYHDDDELILPVKRKVDKKKPLALRRKPLPPVGFAGAMAEAREKGDLTFTFPVVFMGESDDDDTPVWEPLPLKTLKELQSAVRTMGPSAPYTLQVVDMVASQ... | viral budding via host ESCRT complex viral nucleocapsid DNA binding nucleotide binding structural constituent of virion zinc ion binding Mouse mammary tumor virus 3D-structure Capsid protein Direct protein sequencing DNA-binding Host-virus interaction Lipoprotein Metal-binding Myristate Nucleotide-binding Phosphoprote... |
positive regulation of transcription by RNA polymerase II protein phosphorylation regulation of transcription by RNA polymerase II signal transduction | chromatin; cytosol; nucleoplasm; nucleus; ribonucleoprotein complex | chromatin binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Homo sapiens | 3D-structure Alternative splicing Chromosomal rearrangement Cytoplasm DNA-binding Isopeptide bond Nucleus Phosphoprotein Proto-oncogene Reference proteome Transcription Transcription regulation Ubl conjugation | MASTIKEALS | MASTIKEALSVVSEDQSLFECAYGTPHLAKTEMTASSSSDYGQTSKMSPRVPQQDWLSQPPARVTIKMECNPSQVNGSRNSPDECSVAKGGKMVGSPDTVGMNYGSYMEEKHMPPPNMTTNERRVIVPADPTLWSTDHVRQWLEWAVKEYGLPDVNILLFQNIDGKELCKMTKDDFQRLTPSYNADILLSHLHYLRETPLPHLTSDDVDKALQNSPRLMHARNTGGAAFIFPNTSVYPEATQRITTRPDLPYEPPRRSAWTGHGHPTPQSKAAQPSPSTVPKTEDQRPQLDPYQILGPTSSRLANPGSGQIQLWQFLLEL... | positive regulation of transcription by RNA polymerase II protein phosphorylation regulation of transcription by RNA polymerase II signal transduction chromatin; cytosol; nucleoplasm; nucleus; ribonucleoprotein complex chromatin binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specifi... |
apoptotic process cell cycle cellular detoxification cellular response to type II interferon negative regulation of apoptotic process negative regulation of DNA-binding transcription factor activity negative regulation of innate immune response positive regulation of brown fat cell differentiation positive regulation o... | cytoplasm; cytosol; nucleolus; nucleoplasm; nucleus; plasma membrane | ATP binding manganese ion binding protein serine kinase activity protein serine/threonine kinase activator activity protein serine/threonine kinase activity ribosomal small subunit binding transcription factor binding | Homo sapiens | 3D-structure Alternative initiation Apoptosis ATP-binding Cell cycle Cell membrane Cytoplasm Direct protein sequencing Host-virus interaction Kinase Magnesium Membrane Metal-binding Nucleotide-binding Nucleus Phosphoprotein Proto-oncogene Reference proteome Serine/threonine-protein kinase Transferase Ubl conjugation | MLLSKINSLA | MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLHSLSPGPSK | apoptotic process cell cycle cellular detoxification cellular response to type II interferon negative regulation of apoptotic process negative regulation of DNA-binding transcription factor activity negative regulation of innate immune response positive regulation of brown fat cell differentiation positive regulation o... |
cardiac muscle cell differentiation carnitine biosynthetic process carnitine metabolic process, CoA-linked fatty acid beta-oxidation fatty acid beta-oxidation using acyl-CoA dehydrogenase glycogen biosynthetic process liver development medium-chain fatty acid catabolic process medium-chain fatty acid metabolic process ... | axon; cytoplasm; mitochondrial matrix; mitochondrial membrane; mitochondrion; nucleus | acyl-CoA dehydrogenase activity flavin adenine dinucleotide binding identical protein binding medium-chain-acyl-CoA dehydrogenase activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Direct protein sequencing Disease variant FAD Fatty acid metabolism Flavoprotein Lipid metabolism Mitochondrion Oxidoreductase Phosphoprotein Reference proteome Transit peptide | MAAGFGRCCR | MAAGFGRCCRVLRSISRFHWRSQHTKANRQREPGLGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAIS... | cardiac muscle cell differentiation carnitine biosynthetic process carnitine metabolic process, CoA-linked fatty acid beta-oxidation fatty acid beta-oxidation using acyl-CoA dehydrogenase glycogen biosynthetic process liver development medium-chain fatty acid catabolic process medium-chain fatty acid metabolic process ... |
Group I intron splicing leucyl-tRNA aminoacylation mitochondrial translation mRNA processing | mitochondrial matrix; mitochondrion | aminoacyl-tRNA editing activity ATP binding leucine-tRNA ligase activity pre-mRNA intronic binding | Saccharomyces cerevisiae | Aminoacyl-tRNA synthetase ATP-binding Direct protein sequencing Ligase Mitochondrion Nucleotide-binding Protein biosynthesis Reference proteome Transit peptide | MLSRPSSRFL | MLSRPSSRFLSTKRGPGPAVKKLIAIGEKWKQKTTRGLPKQDTLNSGSKYILCQFPYPSGALHIGHLRVYVISDSLNRFYKQKGYNVIHPMGWDAFGLPAENAAIERSINPAIWTRDNIAKMKQQMQSMLANFDWDREITTCDPEYYKFTQWIFLKLFENGLAYRKEAEINWDPVDMTVLANEQVDAQGRSWRSGAIVEKKQLKQWFLGITKFAPKLKKHLNQLKDWPSNVKQMQKNWIGESVGAELVFKVADPKFENLIVFTTRPETLFAVQYVALALDHPIVQKYCEEMPDLKEFIQKSDQLPNDTKEGFQLPNIKAV... | Group I intron splicing leucyl-tRNA aminoacylation mitochondrial translation mRNA processing mitochondrial matrix; mitochondrion aminoacyl-tRNA editing activity ATP binding leucine-tRNA ligase activity pre-mRNA intronic binding Saccharomyces cerevisiae Aminoacyl-tRNA synthetase ATP-binding Direct protein sequencing Li... |
cell population proliferation melanin biosynthetic process pigmentation response to blue light response to cAMP response to UV response to vitamin D thymus development | cytoplasm; intracellular membrane-bounded organelle; melanosome; melanosome membrane; membrane; perinuclear region of cytoplasm | copper ion binding identical protein binding protein homodimerization activity tyrosinase activity | Mus musculus | Albinism Copper Disease variant Glycoprotein Melanin biosynthesis Membrane Metal-binding Monooxygenase Oxidoreductase Reference proteome Signal Transmembrane Transmembrane helix | MFLAVLYCLL | MFLAVLYCLLWSFQISDGHFPRACASSKNLLAKECCPPWMGDGSPCGQLSGRGSCQDILLSSAPSGPQFPFKGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFGGPNCTEKRVLIRRNIFDLSVSEKNKFFSYLTLAKHTISSVYVIPTGTYGQMNNGSTPMFNDINIYDLFVWMHYYVSRDTLLGGSEIWRDIDFAHEAPGFLPWHRLFLLLWEQEIRELTGDENFTVPYWDWRDAENCDICTDEYLGGRHPENPNLLSPASFFSSWQIICSRSEEYNSHQVLCDGTPEGPLLRNPGNHDKAKTPRLPSSADVEF... | cell population proliferation melanin biosynthetic process pigmentation response to blue light response to cAMP response to UV response to vitamin D thymus development cytoplasm; intracellular membrane-bounded organelle; melanosome; melanosome membrane; membrane; perinuclear region of cytoplasm copper ion binding ident... |
cellular response to xenobiotic stimulus L-phenylalanine catabolic process liver development response to aluminum ion response to glucagon response to lead ion tetrahydrobiopterin biosynthetic process | cytoplasm | 6,7-dihydropteridine reductase activity identical protein binding NADH binding NADPH binding | Rattus norvegicus | 3D-structure Direct protein sequencing NADP Oxidoreductase Phosphoprotein Reference proteome Tetrahydrobiopterin biosynthesis | MAASGEARRV | MAASGEARRVLVYGGRGALGSRCVQAFRARNWWVASIDVVENEEASASVIVKMTDSFTEQADQVTAEVGKLLGDQKVDAILCVAGGWAGGNAKSKSLFKNCDLMWKQSIWTSTISSHLATKHLKEGGLLTLAGAKAALDGTPGMIGYGMAKGAVHQLCQSLAGKNSGMPSGAAAIAVLPVTLDTPMNRKSMPEADFSSWTPLEFLVETFHDWITGNKRPNSGSLIQVVTTDGKTELTPAYF | cellular response to xenobiotic stimulus L-phenylalanine catabolic process liver development response to aluminum ion response to glucagon response to lead ion tetrahydrobiopterin biosynthetic process cytoplasm 6,7-dihydropteridine reductase activity identical protein binding NADH binding NADPH binding Rattus norvegicu... |
anaerobic electron transport chain anaerobic respiration nitrate assimilation nitrate metabolic process | membrane; NarGHI complex | 3 iron, 4 sulfur cluster binding 4 iron, 4 sulfur cluster binding electron transfer activity metal ion binding nitrate reductase activity | Escherichia coli | 3D-structure 3Fe-4S 4Fe-4S Cell membrane Direct protein sequencing Electron transport Iron Iron-sulfur Membrane Metal-binding Nitrate assimilation Oxidoreductase Reference proteome Repeat Transport | MKIRSQVGMV | MKIRSQVGMVLNLDKCIGCHTCSVTCKNVWTSREGVEYAWFNNVETKPGQGFPTDWENQEKYKGGWIRKINGKLQPRMGNRAMLLGKIFANPHLPGIDDYYEPFDFDYQNLHTAPEGSKSQPIARPRSLITGERMAKIEKGPNWEDDLGGEFDKLAKDKNFDNIQKAMYSQFENTFMMYLPRLCEHCLNPACVATCPSGAIYKREEDGIVLIDQDKCRGWRMCITGCPYKKIYFNWKSGKSEKCIFCYPRIEAGQPTVCSETCVGRIRYLGVLLYDADAIERAASTENEKDLYQRQLDVFLDPNDPKVIEQAIKDGIPLS... | anaerobic electron transport chain anaerobic respiration nitrate assimilation nitrate metabolic process membrane; NarGHI complex 3 iron, 4 sulfur cluster binding 4 iron, 4 sulfur cluster binding electron transfer activity metal ion binding nitrate reductase activity Escherichia coli 3D-structure 3Fe-4S 4Fe-4S Cell memb... |
anaerobic electron transport chain anaerobic respiration nitrate assimilation nitrate metabolic process | membrane; NarGHI complex; nitrate reductase complex; plasma membrane | electron transfer activity heme binding metal ion binding nitrate reductase activity | Escherichia coli | 3D-structure Cell inner membrane Cell membrane Direct protein sequencing Electron transport Formylation Heme Iron Membrane Metal-binding Nitrate assimilation Oxidoreductase Reference proteome Transmembrane Transmembrane helix Transport | MQFLNMFFFD | MQFLNMFFFDIYPYIAGAVFLIGSWLRYDYGQYTWRAASSQMLDRKGMNLASNLFHIGILGIFVGHFFGMLTPHWMYEAWLPIEVKQKMAMFAGGASGVLCLIGGVLLLKRRLFSPRVRATTTGADILILSLLVIQCALGLLTIPFSAQHMDGSEMMKLVGWAQSVVTFHGGASQHLDGVAFIFRLHLVLGMTLFLLFPFSRLIHIWSVPVEYLTRKYQLVRARH | anaerobic electron transport chain anaerobic respiration nitrate assimilation nitrate metabolic process membrane; NarGHI complex; nitrate reductase complex; plasma membrane electron transfer activity heme binding metal ion binding nitrate reductase activity Escherichia coli 3D-structure Cell inner membrane Cell membran... |
heme biosynthetic process protoporphyrinogen IX biosynthetic process | cytoplasm; cytosol | coproporphyrinogen oxidase activity protein homodimerization activity | Saccharomyces cerevisiae | 3D-structure Cytoplasm Direct protein sequencing Disulfide bond Heme biosynthesis Oxidoreductase Porphyrin biosynthesis Reference proteome | MPAPQDPRNL | MPAPQDPRNLPIRQQMEALIRRKQAEITQGLESIDTVKFHADTWTRGNDGGGGTSMVIQDGTTFEKGGVNVSVVYGQLSPAAVSAMKADHKNLRLPEDPKTGLPVTDGVKFFACGLSMVIHPVNPHAPTTHLNYRYFETWNQDGTPQTWWFGGGADLTPSYLYEEDGQLFHQLHKDALDKHDTALYPRFKKWCDEYFYITHRKETRGIGGIFFDDYDERDPQEILKMVEDCFDAFLPSYLTIVKRRKDMPYTKEEQQWQAIRRGRYVEFNLIYDRGTQFGLRTPGSRVESILMSLPEHASWLYNHHPAPGSREAKLLEVT... | heme biosynthetic process protoporphyrinogen IX biosynthetic process cytoplasm; cytosol coproporphyrinogen oxidase activity protein homodimerization activity Saccharomyces cerevisiae 3D-structure Cytoplasm Direct protein sequencing Disulfide bond Heme biosynthesis Oxidoreductase Porphyrin biosynthesis Reference proteo... |
acrosome reaction binding of sperm to zona pellucida flagellated sperm motility penetration of zona pellucida positive regulation of protein processing sperm DNA condensation spermatogenesis | male germ cell nucleus; nucleosome; nucleus | DNA binding zinc ion binding | Mus musculus | Chromosome Developmental protein Differentiation DNA-binding Metal-binding Nucleosome core Nucleus Phosphoprotein Reference proteome Spermatogenesis Zinc | MDTKMQSLPT | MDTKMQSLPTTHPHPHSSSRPQSHTSNQCNQCTCSHHCRSCSQAGHAGSSSSPSPGPPMKHPKPSVHSRHSPARPSHRGSCPKNRKTFEGKVSKRKAVRRRKRTHRAKRRSSGRRYK | acrosome reaction binding of sperm to zona pellucida flagellated sperm motility penetration of zona pellucida positive regulation of protein processing sperm DNA condensation spermatogenesis male germ cell nucleus; nucleosome; nucleus DNA binding zinc ion binding Mus musculus Chromosome Developmental protein Differenti... |
photorespiration reductive pentose-phosphate cycle | chloroplast | magnesium ion binding monooxygenase activity ribulose-bisphosphate carboxylase activity | Triticum aestivum | 3D-structure Acetylation Calvin cycle Carbon dioxide fixation Chloroplast Direct protein sequencing Disulfide bond Lyase Magnesium Metal-binding Monooxygenase Oxidoreductase Photorespiration Photosynthesis Plastid Reference proteome | MSPQTETKAG | MSPQTETKAGVGFKAGVKDYKLTYYTPEYETKDTDILAAFRVSPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEDSQWICYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPTYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRACYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEAIYKSQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTTLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRM... | photorespiration reductive pentose-phosphate cycle chloroplast magnesium ion binding monooxygenase activity ribulose-bisphosphate carboxylase activity Triticum aestivum 3D-structure Acetylation Calvin cycle Carbon dioxide fixation Chloroplast Direct protein sequencing Disulfide bond Lyase Magnesium Metal-binding Monoox... |
brain development dentate gyrus development diet induced thermogenesis embryonic digestive tract development hippocampus development intracellular water homeostasis negative regulation of gastrin-induced gastric acid secretion negative regulation of neuron apoptotic process neuron apoptotic process neuronal stem cell p... | extracellular space | digestive hormone activity G protein-coupled receptor binding hormone activity signaling receptor binding | Rattus norvegicus | Amidation Cleavage on pair of basic residues Direct protein sequencing Hormone Phosphoprotein Reference proteome Secreted Signal | MEPLLPTPPL | MEPLLPTPPLLLLLLLLLSSSFVLPAPPRTPRHSDGTFTSELSRLQDSARLQRLLQGLVGKRSEEDTENIPENSVARPKPLEDQLCLLWSNTQALQDWLLPRLSLDGSLSLWLPPGPRPAVDHSEWTETTRQPR | brain development dentate gyrus development diet induced thermogenesis embryonic digestive tract development hippocampus development intracellular water homeostasis negative regulation of gastrin-induced gastric acid secretion negative regulation of neuron apoptotic process neuron apoptotic process neuronal stem cell p... |
chromatin remodeling chromosome segregation circadian regulation of gene expression circadian rhythm DNA replication DNA topological change embryonic cleavage peptidyl-serine phosphorylation phosphorylation programmed cell death response to xenobiotic stimulus | chromosome; fibrillar center; male germ cell nucleus; nucleolus; nucleoplasm; nucleus; P-body; perikaryon; protein-DNA complex | ATP binding chromatin binding DNA binding DNA binding, bending DNA topoisomerase type I (single strand cut, ATP-independent) activity double-stranded DNA binding protein domain specific binding protein serine/threonine kinase activity RNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sin... | Homo sapiens | 3D-structure Acetylation Biological rhythms Chromosomal rearrangement Direct protein sequencing DNA-binding Host-virus interaction Isomerase Isopeptide bond Nucleus Phosphoprotein Proto-oncogene Reference proteome Topoisomerase Ubl conjugation | MSGDHLHNDS | MSGDHLHNDSQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPENVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMSQYFKAQTEARKQMS... | chromatin remodeling chromosome segregation circadian regulation of gene expression circadian rhythm DNA replication DNA topological change embryonic cleavage peptidyl-serine phosphorylation phosphorylation programmed cell death response to xenobiotic stimulus chromosome; fibrillar center; male germ cell nucleus; nucle... |
brown fat cell differentiation cholesterol homeostasis intracellular lipid transport long-chain fatty acid transport phospholipid homeostasis positive regulation of long-chain fatty acid import into cell positive regulation of phospholipid biosynthetic process regulation of fatty acid oxidation regulation of phosphatid... | cytosol; extracellular space; nucleus; sarcoplasm | cytoskeletal protein binding fatty acid binding icosatetraenoic acid binding long-chain fatty acid binding long-chain fatty acid transporter activity oleic acid binding | Mus musculus | 3D-structure Acetylation Cytoplasm Direct protein sequencing Lipid-binding Phosphoprotein Reference proteome Transport | MADAFVGTWK | MADAFVGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDTITIKTQSTFKNTEINFQLGIEFDEVTADDRKVKSLVTLDGGKLIHVQKWNGQETTLTRELVDGKLILTLTHGSVVSTRTYEKEA | brown fat cell differentiation cholesterol homeostasis intracellular lipid transport long-chain fatty acid transport phospholipid homeostasis positive regulation of long-chain fatty acid import into cell positive regulation of phospholipid biosynthetic process regulation of fatty acid oxidation regulation of phosphatid... |
arachidonic acid secretion lipid catabolic process phospholipid metabolic process | extracellular region | calcium ion binding phospholipase A2 activity toxin activity | Vipera ammodytes ammodytes | 3D-structure Blood coagulation cascade inhibiting toxin Calcium Direct protein sequencing Disulfide bond Hemostasis impairing toxin Host cytoplasm Hydrolase Lipid degradation Lipid metabolism Metal-binding Neurotoxin Presynaptic neurotoxin Secreted Signal Toxin | MRTLWIVAVC | MRTLWIVAVCLIGVEGSLLEFGMMILGETGKNPLTSYSFYGCYCGVGGKGTPKDATDRCCFVHDCCYGNLPDCSPKTDRYKYHRENGAIVCGKGTSCENRICECDRAAAICFRKNLKTYNYIYRNYPDILCKEESEKC | arachidonic acid secretion lipid catabolic process phospholipid metabolic process extracellular region calcium ion binding phospholipase A2 activity toxin activity Vipera ammodytes ammodytes 3D-structure Blood coagulation cascade inhibiting toxin Calcium Direct protein sequencing Disulfide bond Hemostasis impairing tox... |
glucose metabolic process NADPH regeneration pentose-phosphate shunt, oxidative branch response to hydrogen peroxide | cytoplasm; cytosol | glucose-6-phosphate dehydrogenase activity NADP binding | Saccharomyces cerevisiae | Acetylation Carbohydrate metabolism Direct protein sequencing Glucose metabolism NADP Oxidoreductase Phosphoprotein Reference proteome | MSEGPVKFEK | MSEGPVKFEKNTVISVFGASGDLAKKKTFPALFGLFREGYLDPSTKIFGYARSKLSMEEDLKSRVLPHLKKPHGEADDSKVEQFFKMVSYISGNYDTDEGFDELRTQIEKFEKSANVDVPHRLFYLALPPSVFLTVAKQIKSRVYAENGITRVIVEKPFGHDLASARELQKNLGPLFKEEELYRIDHYLGKELVKNLLVLRFGNQFLNASWNRDNIQSVQISFKERFGTEGRGGYFDSIGIIRDVMQNHLLQIMTLLTMERPVSFDPESIRDEKVKVLKAVAPIDTDDVLLGQYGKSEDGSKPAYVDDDTVDKDSKCVTF... | glucose metabolic process NADPH regeneration pentose-phosphate shunt, oxidative branch response to hydrogen peroxide cytoplasm; cytosol glucose-6-phosphate dehydrogenase activity NADP binding Saccharomyces cerevisiae Acetylation Carbohydrate metabolism Direct protein sequencing Glucose metabolism NADP Oxidoreductase P... |
cellular response to oxidative stress cholesterol biosynthetic process erythrocyte maturation glucose 6-phosphate metabolic process glucose metabolic process glutathione metabolic process lipid metabolic process NADP metabolic process NADPH regeneration negative regulation of cell growth involved in cardiac muscle cell... | centriolar satellite; cytoplasm; cytoplasmic side of plasma membrane; cytosol; extracellular exosome; intracellular membrane-bounded organelle; membrane | glucose binding glucose-6-phosphate dehydrogenase activity identical protein binding NADP binding protein homodimerization activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Carbohydrate metabolism Cytoplasm Direct protein sequencing Disease variant Glucose metabolism Hereditary hemolytic anemia Hydroxylation Membrane NADP Oxidoreductase Phosphoprotein Reference proteome | MAEQVALSRT | MAEQVALSRTQVCGILREELFQGDAFHQSDTHIFIIMGASGDLAKKKIYPTIWWLFRDGLLPENTFIVGYARSRLTVADIRKQSEPFFKATPEEKLKLEDFFARNSYVAGQYDDAASYQRLNSHMNALHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSSDRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEPFGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTNSDDVRDEKVKVLKCISEVQANNVVLGQYVGNPDGEGEATK... | cellular response to oxidative stress cholesterol biosynthetic process erythrocyte maturation glucose 6-phosphate metabolic process glucose metabolic process glutathione metabolic process lipid metabolic process NADP metabolic process NADPH regeneration negative regulation of cell growth involved in cardiac muscle cell... |
chaeta morphogenesis female sex determination follicle cell of egg chamber development hindgut development Malpighian tubule tip cell differentiation neuroblast fate determination neuroendocrine cell differentiation neuron fate commitment oogenesis positive regulation of DNA-templated transcription positive regulation ... | nucleus; transcription regulator complex | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor binding protein heterodimerization activity protein homodimerization activity sequence-specific DNA binding | Drosophila melanogaster | Activator Developmental protein Differentiation DNA-binding Neurogenesis Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation | MATSDDEPMH | MATSDDEPMHLYEVFQNCFNKIANKQPTGTVGADRGGGGGYHSPYGSLGVENGMYPSDFNSMHDTVNGGNNRYANASTVDQYFDSAAAGSGGAWCQPQMSSANSYMGQSAYQNSGPLSGHSIDQQQQQVHQADGLGMGGGGGGGVGADGMHCPVTTGLPPISSFRPTSGGIGGPGAGQQAPVNVNVNPPAVFNSPQAHNHNHTVQAQHSALSTAGPLGHHSLNHTPHAHSHTLPLPHALPHGHTLPHPHHSQQNSPAVQSSDAFSGAGASVKVAGAGNSSAAALRQQMYMPADQSISSFGSNPSTPVNSPPPLTQSVVGG... | chaeta morphogenesis female sex determination follicle cell of egg chamber development hindgut development Malpighian tubule tip cell differentiation neuroblast fate determination neuroendocrine cell differentiation neuron fate commitment oogenesis positive regulation of DNA-templated transcription positive regulation ... |
cellular bud site selection chemotropism establishment of cell polarity intracellular signal transduction protein localization to cell cortex regulation of exit from mitosis regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion regulation of Rho protein signal transduction s... | Cdc24p-Far1p-Gbetagamma complex; cell cortex; cellular bud neck; cellular bud tip; cytoplasm; division septum; incipient cellular bud site; mating projection tip; nucleus; PAR polarity complex | guanyl-nucleotide exchange factor activity | Saccharomyces cerevisiae | 3D-structure Guanine-nucleotide releasing factor Reference proteome | MAIQTRFASG | MAIQTRFASGTSLSDLKPKPSATSISIPMQNVMNKPVTEQDSLFHICANIRKRLEVLPQLKPFLQLAYQSSEVLSERQSLLLSQKQHQELLKSNGANRDSSDLAPTLRSSSISTATSLMSMEGISYTNSNPSATPNMEDTLLTFSMGILPITMDCDPVTQLSQLFQQGAPLCILFNSVKPQFKLPVIASDDLKVCKKSIYDFILGCKKHFAFNDEELFTISDVFANSTSQLVKVLEVVETLMNSSPTIFPSKSKTQQIMNAENQHRHQPQQSSKKHNEYVKIIKEFVATERKYVHDLEILDKYRQQLLDSNLITSEELYM... | cellular bud site selection chemotropism establishment of cell polarity intracellular signal transduction protein localization to cell cortex regulation of exit from mitosis regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion regulation of Rho protein signal transduction s... |
autophagic cell death establishment of protein localization to organelle Golgi to lysosome transport granzyme-mediated programmed cell death signaling pathway lysosomal lumen acidification positive regulation of natural killer cell degranulation positive regulation of natural killer cell mediated cytotoxicity protein s... | alveolar lamellar body; autolysosome; autophagosome membrane; cell surface; cytolytic granule; cytolytic granule membrane; cytoplasm; cytosol; dendrite; endosome; endosome membrane; external side of plasma membrane; late endosome; late endosome membrane; lysosomal membrane; lysosome; melanosome; multivesicular body; ne... | enzyme binding ion channel inhibitor activity protein domain specific binding | Mus musculus | 3D-structure Cell membrane Direct protein sequencing Disulfide bond Endosome Glycoprotein Lysosome Membrane Reference proteome Signal Transmembrane Transmembrane helix | MAAPGARRPL | MAAPGARRPLLLLLLAGLAHGASALFEVKNNGTTCIMASFSASFLTTYETANGSQIVNISLPASAEVLKNGSSCGKENVSDPSLTITFGRGYLLTLNFTKNTTRYSVQHMYFTYNLSDTEHFPNAISKEIYTMDSTTDIKADINKAYRCVSDIRVYMKNVTVVLRDATIQAYLSSGNFSKEETHCTQDGPSPTTGPPSPSPPLVPTNPTVSKYNVTGNNGTCLLASMALQLNITYLKKDNKTVTRAFNISPNDTSSGSCGINLVTLKVENKNRALELQFGMNASSSLFFLQGVRLNMTLPDALVPTFSISNHSLKALQAT... | autophagic cell death establishment of protein localization to organelle Golgi to lysosome transport granzyme-mediated programmed cell death signaling pathway lysosomal lumen acidification positive regulation of natural killer cell degranulation positive regulation of natural killer cell mediated cytotoxicity protein s... |
post-translational protein targeting to endoplasmic reticulum membrane protein modification process regulation of protein stability tail-anchored membrane protein insertion into ER membrane ubiquitin-dependent protein catabolic process | BAT3 complex; cytoplasm; cytosol; membrane; nucleoplasm; nucleus | protein-folding chaperone binding ubiquitin-like protein transferase activity | Homo sapiens | 3D-structure Cytoplasm Isopeptide bond Nucleus Phosphoprotein Reference proteome Transport Ubl conjugation | MQLTVKALQG | MQLTVKALQGRECSLQVPEDELVSTLKQLVSEKLNVPVRQQRLLFKGKALADGKRLSDYSIGPNSKLNLVVKPLEKVLLEEGEAQRLADSPPPQVWQLISKVLARHFSAADASRVLEQLQRDYERSLSRLTLDDIERLASRFLHPEVTETMEKGFSK | post-translational protein targeting to endoplasmic reticulum membrane protein modification process regulation of protein stability tail-anchored membrane protein insertion into ER membrane ubiquitin-dependent protein catabolic process BAT3 complex; cytoplasm; cytosol; membrane; nucleoplasm; nucleus protein-folding cha... |
de novo' NAD biosynthetic process from aspartate | cytosol | 4 iron, 4 sulfur cluster binding metal ion binding quinolinate synthetase A activity | Escherichia coli | 4Fe-4S Cytoplasm Direct protein sequencing Disulfide bond Iron Iron-sulfur Metal-binding Pyridine nucleotide biosynthesis Reference proteome Transferase | MSVMFDPDTA | MSVMFDPDTAIYPFPPKPTPLSIDEKAYYREKIKRLLKERNAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHPASTLLVAGVRFMGETAKILSPEKTILMPTLQAECSLDLGCPVEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVELIDHLDSLGEKIIWAPDKHLGRYVQKQTGGDILCWQGACIVHDEFKTQALTRLQEEYPDAAILVHPESPQAIVDMADAVGSTSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWMAMNGLQAIAEALEQEGSNHE... | de novo' NAD biosynthetic process from aspartate cytosol 4 iron, 4 sulfur cluster binding metal ion binding quinolinate synthetase A activity Escherichia coli 4Fe-4S Cytoplasm Direct protein sequencing Disulfide bond Iron Iron-sulfur Metal-binding Pyridine nucleotide biosynthesis Reference proteome Transferase MSVMFDPD... |
female pregnancy regulation of immune system process signal transduction | cell surface; extracellular region; plasma membrane | protein tyrosine kinase binding | Homo sapiens | Alternative splicing Disulfide bond Glycoprotein Immunoglobulin domain Reference proteome Repeat Secreted Signal | MGTLSAPPCT | MGTLSAPPCTQRIKWKGLLLTASLLNFWNLPTTAQVTIEAEPTKVSEGKDVLLLVHNLPQNLTGYIWYKGQMRDLYHYITSYVVDGEIIIYGPAYSGRETAYSNASLLIQNVTREDAGSYTLHIIKGDDGTRGVTGRFTFTLHLETPKPSISSSNLNPRETMEAVSLTCDPETPDASYLWWMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLPKPYITINNLNPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIR... | female pregnancy regulation of immune system process signal transduction cell surface; extracellular region; plasma membrane protein tyrosine kinase binding Homo sapiens Alternative splicing Disulfide bond Glycoprotein Immunoglobulin domain Reference proteome Repeat Secreted Signal MGTLSAPPCT MGTLSAPPCTQRIKWKGLLLTASLLN... |
carnitine metabolic process coenzyme A metabolic process fatty acid beta-oxidation fatty acid metabolic process fatty acid transport generation of precursor metabolites and energy long-chain fatty acid transport medium-chain fatty acid metabolic process medium-chain fatty acid transport response to organonitrogen compo... | peroxisome | carnitine O-octanoyltransferase activity | Rattus norvegicus | Acetylation Acyltransferase Fatty acid metabolism Lipid metabolism Peroxisome Reference proteome Transferase Transport | MENQLAKSIE | MENQLAKSIEERTFQYQDSLPPLPVPSLEESLKKYLESVKPFANEDEYKKTEEIVQKFQDGVGKTLHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFVGPSPHFEHYWPAREGTQLERGSILLWHNLNYWQLLRREKLPVHKSGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFKTESEGHCPTHIAVLCRGRAFVFDVLHDGCLITPPELLRQLTYIYQKCWNEPVGPSIAALTSEERTRWAKAREYLIGLDPENLTLLEKIQSSLFVYSIEDTSPHATPENFSQVFEMLLGGDPAVRWGDKSYNLISFANGI... | carnitine metabolic process coenzyme A metabolic process fatty acid beta-oxidation fatty acid metabolic process fatty acid transport generation of precursor metabolites and energy long-chain fatty acid transport medium-chain fatty acid metabolic process medium-chain fatty acid transport response to organonitrogen compo... |
intracellular steroid hormone receptor signaling pathway positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of transcription by RNA polymerase II | chromatin; cytoplasm; fibrillar center; intercellular bridge; microtubule cytoskeleton; nucleoplasm; nucleus | DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific estrogen response element binding nuclear receptor activity nuclear steroid receptor activity protein domain specific binding sequence-specific DNA binding sequence-specific double-stranded DNA binding steroi... | Homo sapiens | 3D-structure Acetylation Alternative splicing Cytoplasm Direct protein sequencing DNA-binding Isopeptide bond Metal-binding Nucleus Phosphoprotein Receptor Reference proteome Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | MSSQVVGIEP | MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALR... | intracellular steroid hormone receptor signaling pathway positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of transcription by RNA polymerase II chromatin; cytoplasm; fibrillar center; intercellular bridge; microtubule cytoskeleton; nucleoplasm; nucleus DNA-b... |
cell dedifferentiation cell population proliferation embryonic placenta development in utero embryonic development inner ear development intracellular steroid hormone receptor signaling pathway negative regulation of DNA-templated transcription negative regulation of stem cell differentiation photoreceptor cell mainten... | condensed chromosome; cytoplasm; integrator complex; nucleus | cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific estrogen response element binding nuclear receptor activity nuclear steroid recepto... | Rattus norvegicus | Acetylation Chromosome Cytoplasm DNA-binding Metal-binding Nucleus Receptor Reference proteome Transcription Transcription regulation Zinc Zinc-finger | MSSEDRHLGS | MSSEDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGMALGTHANGLDSPPMFAGAGLGGNPCRKSYEDCTSGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRLDSENSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPDDVPEGDIKALTTLCDLADRELVFLISWAKHIPGFSNLTLGDQMSLLQSAWMEILILGIVYRSLPYDDKLAYAEDYIMDEEHSRLVGLLEL... | cell dedifferentiation cell population proliferation embryonic placenta development in utero embryonic development inner ear development intracellular steroid hormone receptor signaling pathway negative regulation of DNA-templated transcription negative regulation of stem cell differentiation photoreceptor cell mainten... |
antibacterial humoral response antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to lipopolysaccharide defense response to bacterium defense response to Gram-negative bacterium defense response to Gram-positive bacterium disruption of plasma membrane integrity in another organism... | extracellular space; intracellular membrane-bounded organelle; midbody; secretory granule | pore-forming activity protein homodimerization activity | Mus musculus | Antibiotic Antimicrobial Defensin Direct protein sequencing Disulfide bond Reference proteome Secreted Signal | MKKLVLLFAL | MKKLVLLFALVLLGFQVQADSIQNTDEETKTEEQPGEEDQAVSVSFGDPEGTSLQEESLRDLVCYCRSRGCKGRERMNGTCRKGHLLYTLCCR | antibacterial humoral response antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to lipopolysaccharide defense response to bacterium defense response to Gram-negative bacterium defense response to Gram-positive bacterium disruption of plasma membrane integrity in another organism... |
adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway chemical synaptic transmission G protein-coupled acetylcholine receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger positive regulation of smooth muscle contraction r... | basolateral plasma membrane; dendrite; endoplasmic reticulum membrane; plasma membrane; postsynaptic membrane; synapse | acetylcholine binding G protein-coupled acetylcholine receptor activity G protein-coupled serotonin receptor activity | Sus scrofa | Cell membrane Disulfide bond Endoplasmic reticulum G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Postsynaptic cell membrane Receptor Reference proteome Synapse Transducer Transmembrane Transmembrane helix | MTLHNNNTTS | MTLHNNNTTSPLFPNISSSWIHGPSDAGLPPGTVTHFGSYNISQAAGNFSSPNGTTSDPLGGHTIWQVVFIAFLTGILALVTIIGNILVIVAFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFTTYIIMNRWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAGVMIGLAWVISFILWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAFYMPVTIMTILYWRIYKETEKRTKELAGLQASGTEAEAENFVHPTGSSRSCSSYELQQQSLKRSARRKYGRCHFWFTTKSW... | adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway chemical synaptic transmission G protein-coupled acetylcholine receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger positive regulation of smooth muscle contraction r... |
de novo' cotranslational protein folding chaperone cofactor-dependent protein refolding cytoplasmic translation protein refolding regulation of translational fidelity ribosomal subunit export from nucleus rRNA processing translational frameshifting translational termination | cytoplasm; cytosol; nucleus; plasma membrane | ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone calmodulin binding heat shock protein binding protein folding chaperone unfolded protein binding | Saccharomyces cerevisiae | 3D-structure Acetylation ATP-binding Chaperone Cytoplasm Direct protein sequencing Hydrolase Nucleotide-binding Phosphoprotein Protein biosynthesis Reference proteome | MAEGVFQGAI | MAEGVFQGAIGIDLGTTYSCVATYESSVEIIANEQGNRVTPSFVAFTPEERLIGDAAKNQAALNPRNTVFDAKRLIGRRFDDESVQKDMKTWPFKVIDVDGNPVIEVQYLEETKTFSPQEISAMVLTKMKEIAEAKIGKKVEKAVITVPAYFNDAQRQATKDAGAISGLNVLRIINEPTAAAIAYGLGAGKSEKERHVLIFDLGGGTFDVSLLHIAGGVYTVKSTSGNTHLGGQDFDTNLLEHFKAEFKKKTGLDISDDARALRRLRTAAERAKRTLSSVTQTTVEVDSLFDGEDFESSLTRARFEDLNAALFKSTLEPV... | de novo' cotranslational protein folding chaperone cofactor-dependent protein refolding cytoplasmic translation protein refolding regulation of translational fidelity ribosomal subunit export from nucleus rRNA processing translational frameshifting translational termination cytoplasm; cytosol; nucleus; plasma membrane ... |
carbohydrate metabolic process viral budding from plasma membrane | host cell plasma membrane; membrane; virion membrane | exo-alpha-(2->3)-sialidase activity exo-alpha-(2->6)-sialidase activity exo-alpha-(2->8)-sialidase activity metal ion binding | Influenza A virus | Calcium Disulfide bond Glycoprotein Glycosidase Host cell membrane Host membrane Hydrolase Membrane Metal-binding Signal-anchor Transmembrane Transmembrane helix Virion | MNPNQKIITI | MNPNQKIITIGSICMTIGIISLILQIGNIISIWVSHSIQTGSQNHTGICNQRIITYENSTWVNQTYVNINNTNVVAGKDTTSVTLAGNSSLCPIRGWAIYSKDNSIRIGSKGDVFVIREPFISCSHLECRTFFLTQGALLNDKHSNGTVKDRSPYRALMSCPIGEAPSPYNSRFESVAWSASACHDGMGWLTIGISGPDDGAVAVLKYNGIITETIKSWRKRILRTQESECVCVNGSCFTIMTDGPSNGPASYRIFKIEKGKITKSIELDAPNSHYEECSCYPDTGTVMCVCRDNWHGSNRPWVSFNQNLDYQIGYICSG... | carbohydrate metabolic process viral budding from plasma membrane host cell plasma membrane; membrane; virion membrane exo-alpha-(2->3)-sialidase activity exo-alpha-(2->6)-sialidase activity exo-alpha-(2->8)-sialidase activity metal ion binding Influenza A virus Calcium Disulfide bond Glycoprotein Glycosidase Host cell... |
anatomical structure morphogenesis animal organ morphogenesis cell differentiation cell-cell signaling fibroblast growth factor receptor signaling pathway negative regulation of cardiac muscle tissue development positive regulation of cell division positive regulation of cell population proliferation positive regulatio... | cytoplasm; extracellular region; extracellular space | fibroblast growth factor receptor binding growth factor activity | Homo sapiens | Developmental protein Differentiation Disease variant Glycoprotein Growth factor Mitogen Proto-oncogene Reference proteome Secreted Signal | MGLIWLLLLS | MGLIWLLLLSLLEPGWPAAGPGARLRRDAGGRGGVYEHLGGAPRRRKLYCATKYHLQLHPSGRVNGSLENSAYSILEITAVEVGIVAIRGLFSGRYLAMNKRGRLYASEHYSAECEFVERIHELGYNTYASRLYRTVSSTPGARRQPSAERLWYVSVNGKGRPRRGFKTRRTQKSSLFLPRVLDHRDHEMVRQLQSGLPRPPGKGVQPRRRRQKQSPDNLEPSHVQASRLGSQLEASAH | anatomical structure morphogenesis animal organ morphogenesis cell differentiation cell-cell signaling fibroblast growth factor receptor signaling pathway negative regulation of cardiac muscle tissue development positive regulation of cell division positive regulation of cell population proliferation positive regulatio... |
adenylate cyclase-modulating G protein-coupled receptor signaling pathway background adaptation cell population proliferation cellular response to electrical stimulus detection of chemical stimulus involved in sensory perception of bitter taste detection of light stimulus involved in visual perception dopamine secretio... | apical plasma membrane; cytosol; heterotrimeric G-protein complex; membrane; neuronal cell body; photoreceptor connecting cilium; photoreceptor disc membrane; photoreceptor inner segment; photoreceptor outer segment; photoreceptor outer segment membrane; plasma membrane | acyl binding G protein-coupled receptor binding G-protein beta/gamma-subunit complex binding GDP binding GTP binding GTPase activity metal ion binding protein kinase binding | Homo sapiens | 3D-structure ADP-ribosylation Cell projection Congenital stationary night blindness Disease variant GTP-binding Lipoprotein Magnesium Membrane Metal-binding Myristate Nucleotide-binding Phosphoprotein Reference proteome Sensory transduction Transducer Vision | MGAGASAEEK | MGAGASAEEKHSRELEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGYSLEECLEFIAIIYGNTLQSILAIVRAMTTLNIQYGDSARQDDARKLMHMADTIEEGTMPKEMSDIIQRLWKDSGIQACFERASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSRVKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDDEVNRMHESLHLFNSICNHRYFATTSIVLFLNKKDVFFEKIKKAHLSICFPDYDGPNTYEDAGNYIKVQFLELNMRRDVKEIYSHMT... | adenylate cyclase-modulating G protein-coupled receptor signaling pathway background adaptation cell population proliferation cellular response to electrical stimulus detection of chemical stimulus involved in sensory perception of bitter taste detection of light stimulus involved in visual perception dopamine secretio... |
dephosphorylation nicotinamide nucleotide metabolic process | fungal-type vacuole membrane | alkaline phosphatase activity fructose-2,6-bisphosphate 6-phosphatase activity metal ion binding | Saccharomyces cerevisiae | Cytoplasm Direct protein sequencing Glycoprotein Hydrolase Magnesium Membrane Metal-binding Phosphoprotein Reference proteome Transmembrane Transmembrane helix Vacuole Zinc | MMTHTLPSEQ | MMTHTLPSEQTRLVPGSDSSSRPKKRRISKRSKIIVSTVVCIGLLLVLVQLAFPSSFALRSASHKKKNVIFFVTDGMGPASLSMARSFNQHVNDLPIDDILTLDEHFIGSSRTRSSDSLVTDSAAGATAFACALKSYNGAIGVDPHHRPCGTVLEAAKLAGYLTGLVVTTRITDATPASFSSHVDYRWQEDLIATHQLGEYPLGRVVDLLMGGGRSHFYPQGEKASPYGHHGARKDGRDLIDEAQSNGWQYVGDRKNFDSLLKSHGENVTLPFLGLFADNDIPFEIDRDEKEYPSLKEQVKVALGALEKASNEDKDSNGF... | dephosphorylation nicotinamide nucleotide metabolic process fungal-type vacuole membrane alkaline phosphatase activity fructose-2,6-bisphosphate 6-phosphatase activity metal ion binding Saccharomyces cerevisiae Cytoplasm Direct protein sequencing Glycoprotein Hydrolase Magnesium Membrane Metal-binding Phosphoprotein R... |
cellular response to heat positive regulation of cell cycle G2/M phase transition positive regulation of cell population proliferation positive regulation of nitric oxide biosynthetic process protein folding protein stabilization response to antibiotic response to cold response to heat response to organic cyclic compou... | axon; cell surface; cytoplasm; cytosol; melanosome; myelin sheath; neuronal cell body; nucleus; perikaryon; perinuclear region of cytoplasm; plasma membrane; protein-containing complex; receptor complex | ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone disordered domain specific binding heat shock protein binding Hsp90 protein binding identical protein binding nitric-oxide synthase regulator activity nuclear estrogen receptor binding nuclear progesterone receptor binding phosphoprotein bindin... | Gallus gallus | ATP-binding Chaperone Cytoplasm Nucleotide-binding Phosphoprotein Reference proteome Stress response | MPEAVQTQDQ | MPEAVQTQDQPMEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKDLKINLIPNKHDRTLTIVDTGIGMTKADLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGSYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRLDNGEPLGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPIRLFVEKERDKEVSDDEAEEKEEEKEEKEEKTEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDEEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHL... | cellular response to heat positive regulation of cell cycle G2/M phase transition positive regulation of cell population proliferation positive regulation of nitric oxide biosynthetic process protein folding protein stabilization response to antibiotic response to cold response to heat response to organic cyclic compou... |
coumarin catabolic process coumarin metabolic process epoxygenase P450 pathway steroid metabolic process xenobiotic catabolic process xenobiotic metabolic process | cytoplasm; cytoplasmic microtubule; endoplasmic reticulum membrane; intracellular membrane-bounded organelle | arachidonic acid epoxygenase activity coumarin 7-hydroxylase activity enzyme binding heme binding iron ion binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | Homo sapiens | 3D-structure Direct protein sequencing Endoplasmic reticulum Heme Iron Lipid metabolism Membrane Metal-binding Microsome Monooxygenase NADP Oxidoreductase Reference proteome | MLASGMLLVA | MLASGMLLVALLVCLTVMVLMSVWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGKRGIEERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQLLQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQEEEKNPNTEFYLKNLVMTTLNLFIGGTETVSTTLRYGFLLLMKH... | coumarin catabolic process coumarin metabolic process epoxygenase P450 pathway steroid metabolic process xenobiotic catabolic process xenobiotic metabolic process cytoplasm; cytoplasmic microtubule; endoplasmic reticulum membrane; intracellular membrane-bounded organelle arachidonic acid epoxygenase activity coumarin 7... |
androgen catabolic process estrogen biosynthetic process female genitalia development female gonad development mammary gland development negative regulation of chronic inflammatory response negative regulation of macrophage chemotaxis positive regulation of estradiol secretion prostate gland growth response to estradio... | endoplasmic reticulum; endoplasmic reticulum membrane; membrane | aromatase activity electron transfer activity heme binding iron ion binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen oxygen binding steroid hydroxylase activity | Homo sapiens | 3D-structure Alternative splicing Direct protein sequencing Disease variant Endoplasmic reticulum Heme Iron Lipid metabolism Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Pseudohermaphroditism Reference proteome Transmembrane Transmembrane helix | MVLEMLNPIH | MVLEMLNPIHYNITSIVPEAMPAATMPVLLLTGLFLLVWNYEGTSSIPGPGYCMGIGPLISHGRFLWMGIGSACNYYNRVYGEFMRVWISGEETLIISKSSSMFHIMKHNHYSSRFGSKLGLQCIGMHEKGIIFNNNPELWKTTRPFFMKALSGPGLVRMVTVCAESLKTHLDRLEEVTNESGYVDVLTLLRRVMLDTSNTLFLRIPLDESAIVVKIQGYFDAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATELILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLF... | androgen catabolic process estrogen biosynthetic process female genitalia development female gonad development mammary gland development negative regulation of chronic inflammatory response negative regulation of macrophage chemotaxis positive regulation of estradiol secretion prostate gland growth response to estradio... |
DNA-templated transcription | cytoplasm; DNA-directed RNA polymerase complex | DNA binding DNA-directed 5'-3' RNA polymerase activity magnesium ion binding zinc ion binding | Sulfolobus acidocaldarius | 3D-structure Cytoplasm DNA-binding DNA-directed RNA polymerase Magnesium Metal-binding Nucleotidyltransferase Reference proteome Transcription Transferase Zinc | MSEKIIRGVK | MSEKIIRGVKFGVLSPNEIRQMSVTAIITSEVYDEDGTPIEGGVMDPKLGVIEPGQKCPVCGNTLAGCPGHFGHIELIKPVIHIGYVKHIYDFLRSTCWRCGRIKIKEQDLERYKRIYNAIKLRWPSAARRLVEYIKKISIKNLECPHCGEKQFKIKLEKPYNFNEERNGSIVKLSPSEIRDRLERIPDSDVELLGYDPKSSRPEWMILTVLPVPPITIRPSITIESGIRAEDDLTHKLVDIIRLNERLKESIEAGAPQLIIEDLWDLLQYHVATYFDNEIPGLPPAKHRSGRPLRTLAQRLKGKEGRFRGNLSGKRVDF... | DNA-templated transcription cytoplasm; DNA-directed RNA polymerase complex DNA binding DNA-directed 5'-3' RNA polymerase activity magnesium ion binding zinc ion binding Sulfolobus acidocaldarius 3D-structure Cytoplasm DNA-binding DNA-directed RNA polymerase Magnesium Metal-binding Nucleotidyltransferase Reference prote... |
carbon dioxide transport cellular oxidant detoxification hydrogen peroxide catabolic process nitric oxide transport oxygen transport | haptoglobin-hemoglobin complex; hemoglobin complex | heme binding hemoglobin alpha binding metal ion binding organic acid binding oxygen binding oxygen carrier activity | Rattus norvegicus | Acetylation Direct protein sequencing Heme Iron Metal-binding Methylation Oxygen transport Phosphoprotein Reference proteome Transport | MVHLTDAEKA | MVHLTDAEKATVSGLWGKVNADNVGAEALGRLLVVYPWTQRYFSKFGDLSSASAIMGNPQVKAHGKKVINAFNDGLKHLDNLKGTFAHLSELHCDKLHVDPENFRLLGNMIVIVLGHHLGKEFTPCAQAAFQKVVAGVASALAHKYH | carbon dioxide transport cellular oxidant detoxification hydrogen peroxide catabolic process nitric oxide transport oxygen transport haptoglobin-hemoglobin complex; hemoglobin complex heme binding hemoglobin alpha binding metal ion binding organic acid binding oxygen binding oxygen carrier activity Rattus norvegicus Ac... |
autophagy cell death oogenesis positive regulation of transcription by RNA polymerase II regulation of development, heterochronic regulation of transcription by RNA polymerase II salivary gland cell autophagic cell death spermatogenesis | nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific sequence-specific DNA binding | Drosophila melanogaster | Alternative splicing Developmental protein DNA-binding Nucleus Reference proteome Transcription Transcription regulation | MIMVQHLVAA | MIMVQHLVAASAHNFASQAAASLVNVSSSSSSSSSSSSSSLSLSSSSSSSSLSSATPTPVASPVTPTSPPPAAAAPAEASPPAGAELQEDGQQAKTQEDPTMKDQDMLEKTRQEVKDPVNVEEPGAIVDTESVMARQSPSPVASTKVPESLEEISNKSPPVQEDEEESESVASDCREFKVLYNHLRQQQHHHSPSSPDKTRSTLDDVSKILWERKQQLQRSSVITAAPTLQPQQHQQPMSDIEDEETLEDVDDADADVEADAEDEELLEQYQNGYDSPLDLSLGGATSAAASAAAAASAVSRRRGRTYSGTESDDSAQCE... | autophagy cell death oogenesis positive regulation of transcription by RNA polymerase II regulation of development, heterochronic regulation of transcription by RNA polymerase II salivary gland cell autophagic cell death spermatogenesis nucleus DNA-binding transcription activator activity, RNA polymerase II-specific DN... |
retina development in camera-type eye signal transduction visual perception | photoreceptor disc membrane; photoreceptor outer segment membrane | 3',5'-cyclic-GMP phosphodiesterase activity 3',5'-cyclic-nucleotide phosphodiesterase activity metal ion binding | Bos taurus | 3D-structure Acetylation Cell membrane Cell projection cGMP Direct protein sequencing Hydrolase Lipoprotein Membrane Metal-binding Methylation Prenylation Reference proteome Repeat Sensory transduction Vision | MGEVTAEEVE | MGEVTAEEVEKFLDSNVSFAKQYYNLRYRAKVISDLLGPREAAVDFSNYHALNSVEESEIIFDLLRDFQDNLQAEKCVFNVMKKLCFLLQADRMSLFMYRARNGIAELATRLFNVHKDAVLEECLVAPDSEIVFPLDMGVVGHVALSKKIVNVPNTEEDEHFCDFVDTLTEYQTKNILASPIMNGKDVVAIIMVVNKVDGPHFTENDEEILLKYLNFANLIMKVFHLSYLHNCETRRGQILLWSGSKVFEELTDIERQFHKALYTVRAFLNCDRYSVGLLDMTKQKEFFDVWPVLMGEAPPYAGPRTPDGREINFYKVID... | retina development in camera-type eye signal transduction visual perception photoreceptor disc membrane; photoreceptor outer segment membrane 3',5'-cyclic-GMP phosphodiesterase activity 3',5'-cyclic-nucleotide phosphodiesterase activity metal ion binding Bos taurus 3D-structure Acetylation Cell membrane Cell projection... |
cinnamic acid biosynthetic process L-phenylalanine catabolic process | cytoplasm | phenylalanine ammonia-lyase activity tyrosine ammonia-lyase activity | Rhodotorula toruloides | 3D-structure Cytoplasm Lyase Phenylalanine catabolism Phenylpropanoid metabolism | MAPSLDSISH | MAPSLDSISHSFANGVASAKQAVNGASTNLAVAGSHLPTTQVTQVDIVEKMLAAPTDSTLELDGYSLNLGDVVSAARKGRPVRVKDSDEIRSKIDKSVEFLRSQLSMSVYGVTTGFGGSADTRTEDAISLQKALLEHQLCGVLPSSFDSFRLGRGLENSLPLEVVRGAMTIRVNSLTRGHSAVRLVVLEALTNFLNHGITPIVPLRGTISASGDLSPLSYIAAAISGHPDSKVHVVHEGKEKILYAREAMALFNLEPVVLGPKEGLGLVNGTAVSASMATLALHDAHMLSLLSQSLTAMTVEAMVGHAGSFHPFLHDVTR... | cinnamic acid biosynthetic process L-phenylalanine catabolic process cytoplasm phenylalanine ammonia-lyase activity tyrosine ammonia-lyase activity Rhodotorula toruloides 3D-structure Cytoplasm Lyase Phenylalanine catabolism Phenylpropanoid metabolism MAPSLDSISH MAPSLDSISHSFANGVASAKQAVNGASTNLAVAGSHLPTTQVTQVDIVEKMLAAPT... |
arabinose transmembrane transport fucose metabolic process fucose transmembrane transport galactose transmembrane transport | membrane; plasma membrane | arabinose:proton symporter activity fucose:proton symporter activity galactose:proton symporter activity | Escherichia coli | 3D-structure Carbohydrate metabolism Cell inner membrane Cell membrane Direct protein sequencing Fucose metabolism Membrane Reference proteome Sugar transport Symport Transmembrane Transmembrane helix Transport | MGNTSIQTQS | MGNTSIQTQSYRAVDKDAGQSRSYIIPFALLCSLFFLWAVANNLNDILLPQFQQAFTLTNFQAGLIQSAFYFGYFIIPIPAGILMKKLSYKAGIITGLFLYALGAALFWPAAEIMNYTLFLVGLFIIAAGLGCLETAANPFVTVLGPESSGHFRLNLAQTFNSFGAIIAVVFGQSLILSNVPHQSQDVLDKMSPEQLSAYKHSLVLSVQTPYMIIVAIVLLVALLIMLTKFPALQSDNHSDAKQGSFSASLSRLARIRHWRWAVLAQFCYVGAQTACWSYLIRYAVEEIPGMTAGFAANYLTGTMVCFFIGRFTGTWLIS... | arabinose transmembrane transport fucose metabolic process fucose transmembrane transport galactose transmembrane transport membrane; plasma membrane arabinose:proton symporter activity fucose:proton symporter activity galactose:proton symporter activity Escherichia coli 3D-structure Carbohydrate metabolism Cell inner ... |
cytokinetic process | cell division site; cell septum; plasma membrane | enzyme activator activity peptidoglycan binding | Escherichia coli | 3D-structure Cell cycle Cell division Cell inner membrane Cell membrane Coiled coil Membrane Reference proteome Transmembrane Transmembrane helix | MDEFKPEDEL | MDEFKPEDELKPDPSDRRTGRSRQSSERSERTERGEPQINFDDIELDDTDDRRPTRAQKERNEEPEIEEEIDESEDETVDEERVERRPRKRKKAASKPASRQYMMMGVGILVLLLLIIGIGSALKAPSTTSSDQTASGEKSIDLAGNATDQANGVQPAPGTTSAENTQQDVSLPPISSTPTQGQTPVATDGQQRVEVQGDLNNALTQPQNQQQLNNVAVNSTLPTEPATVAPVRNGNASRDTAKTQTAERPSTTRPARQQAVIEPKKPQATVKTEPKPVAQTPKRTEPAAPVASTKAPAATSTPAPKETATTAPVQTASP... | cytokinetic process cell division site; cell septum; plasma membrane enzyme activator activity peptidoglycan binding Escherichia coli 3D-structure Cell cycle Cell division Cell inner membrane Cell membrane Coiled coil Membrane Reference proteome Transmembrane Transmembrane helix MDEFKPEDEL MDEFKPEDELKPDPSDRRTGRSRQSSERS... |
methanogenesis | cytoplasm | coenzyme-B sulfoethylthiotransferase activity metal ion binding | Methanothermobacter marburgensis | 3D-structure Cytoplasm Direct protein sequencing Metal-binding Methanogenesis Methylation Nickel Transferase | MADKLFINAL | MADKLFINALKKKFEESPEEKKTTFYTLGGWKQSERKTEFVNAGKEVAAKRGIPQYNPDIGTPLGQRVLMPYQVSTTDTYVEGDDLHFVNNAAMQQMWDDIRRTVIVGLNHAHAVIEKRLGKEVTPETITHYLETVNHAMPGAAVVQEHMVETHPALVADSYVKVFTGNDEIADEIDPAFVIDINKQFPEDQAETLKAEVGDGIWQVVRIPTIVSRTCDGATTSRWSAMQIGMSMISAYKQAAGEAATGDFAYAAKHAEVIHMGTYLPVRRARGENEPGGVPFGYLADICQSSRVNYEDPVRVSLDVVATGAMLYDQIWL... | methanogenesis cytoplasm coenzyme-B sulfoethylthiotransferase activity metal ion binding Methanothermobacter marburgensis 3D-structure Cytoplasm Direct protein sequencing Metal-binding Methanogenesis Methylation Nickel Transferase MADKLFINAL MADKLFINALKKKFEESPEEKKTTFYTLGGWKQSERKTEFVNAGKEVAAKRGIPQYNPDIGTPLGQRVLMPYQVSTT... |
methanogenesis | cytoplasm | coenzyme-B sulfoethylthiotransferase activity | Methanothermobacter marburgensis | 3D-structure Cytoplasm Direct protein sequencing Methanogenesis Transferase | MAKFEDKVDL | MAKFEDKVDLYDDRGNLVEEQVPLEALSPLRNPAIKSIVQGIKRTVAVNLEGIENALKTAKVGGPACKIMGRELDLDIVGNAESIAAAAKEMIQVTEDDDTNVELLGGGKRALVQVPSARFDVAAEYSAAPLVTATAFVQAIINEFDVSMYDANMVKAAVLGRYPQSVEYMGANIATMLDIPQKLEGPGYALRNIMVNHVVAATLKNTLQAAALSTILEQTAMFEMGDAVGAFERMHLLGLAYQGMNADNLVFDLVKANGKEGTVGSVIADLVERALEDGVIKVEKELTDYKVYGTDDLAMWNAYAAAGLMAATMVNQGA... | methanogenesis cytoplasm coenzyme-B sulfoethylthiotransferase activity Methanothermobacter marburgensis 3D-structure Cytoplasm Direct protein sequencing Methanogenesis Transferase MAKFEDKVDL MAKFEDKVDLYDDRGNLVEEQVPLEALSPLRNPAIKSIVQGIKRTVAVNLEGIENALKTAKVGGPACKIMGRELDLDIVGNAESIAAAAKEMIQVTEDDDTNVELLGGGKRALVQVPSARFDVAAEYS... |
methanogenesis | cytoplasm | coenzyme-B sulfoethylthiotransferase activity | Methanothermobacter marburgensis | 3D-structure Cytoplasm Direct protein sequencing Methanogenesis Transferase | MAQYYPGTTK | MAQYYPGTTKVAQNRRNFCNPEYELEKLREISDEDVVKILGHRAPGEEYPSVHPPLEEMDEPEDAIREMVEPIDGAKAGDRVRYIQFTDSMYFAPAQPYVRSRAYLCRYRGADAGTLSGRQIIETRERDLEKISKELLETEFFDPARSGVRGKSVHGHSLRLDEDGMMFDMLRRQIYNKDTGRVEMVKNQIGDELDEPVDLGEPLDEETLMEKTTIYRVDGEAYRDDVEAVEIMQRIHVLRSQGGFNLE | methanogenesis cytoplasm coenzyme-B sulfoethylthiotransferase activity Methanothermobacter marburgensis 3D-structure Cytoplasm Direct protein sequencing Methanogenesis Transferase MAQYYPGTTK MAQYYPGTTKVAQNRRNFCNPEYELEKLREISDEDVVKILGHRAPGEEYPSVHPPLEEMDEPEDAIREMVEPIDGAKAGDRVRYIQFTDSMYFAPAQPYVRSRAYLCRYRGADAGTLSGRQIIETRER... |
actin filament bundle assembly actin filament capping ATP metabolic process glucose mediated signaling pathway negative regulation of actin filament depolymerization regulation of transcription by RNA polymerase II | Golgi apparatus; mitochondrion; nucleus; plant-type vacuole; plasma membrane; plasmodesma; protein-containing complex; proton-transporting V-type ATPase, V1 domain; vacuolar membrane; vacuole | actin filament binding ATP binding proton-transporting ATPase activity, rotational mechanism | Arabidopsis thaliana | Acetylation Hydrogen ion transport Ion transport Membrane Reference proteome Transport Vacuole | MGTNDLDIEE | MGTNDLDIEEGTLEIGMEYRTVSGVAGPLVILDKVKGPKYQEIVNIRLGDGSTRRGQVLEVDGEKAVVQVFEGTSGIDNKFTTVQFTGEVLKTPVSLDMLGRIFNGSGKPIDNGPPILPEAYLDISGSSINPSERTYPEEMIQTGISTIDVMNSIARGQKIPLFSAAGLPHNEIAAQICRQAGLVKRLEKTVDLLEDHGEDNFAIVFAAMGVNMETAQFFKRDFEENGSMERVTLFLNLANDPTIERIITPRIALTTAEYLAYECGKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLATIYERAGRIEGR... | actin filament bundle assembly actin filament capping ATP metabolic process glucose mediated signaling pathway negative regulation of actin filament depolymerization regulation of transcription by RNA polymerase II Golgi apparatus; mitochondrion; nucleus; plant-type vacuole; plasma membrane; plasmodesma; protein-contai... |
10-formyltetrahydrofolate biosynthetic process embryonic neurocranium morphogenesis embryonic viscerocranium morphogenesis heart development methionine biosynthetic process methionine metabolic process neural tube closure neutrophil homeostasis one-carbon metabolic process purine nucleotide biosynthetic process purine ... | cytosol; extracellular exosome; membrane; mitochondrion | ATP binding formate-tetrahydrofolate ligase activity methenyltetrahydrofolate cyclohydrolase activity methylenetetrahydrofolate dehydrogenase (NAD+) activity methylenetetrahydrofolate dehydrogenase (NADP+) activity methylenetetrahydrofolate dehydrogenase activity | Homo sapiens | 3D-structure Acetylation ATP-binding Cytoplasm Direct protein sequencing Disease variant Hydrolase Ligase Multifunctional enzyme NADP Nucleotide-binding One-carbon metabolism Oxidoreductase Phosphoprotein Reference proteome | MAPAEILNGK | MAPAEILNGKEISAQIRARLKNQVTQLKEQVPGFTPRLAILQVGNRDDSNLYINVKLKAAEEIGIKATHIKLPRTTTESEVMKYITSLNEDSTVHGFLVQLPLDSENSINTEEVINAIAPEKDVDGLTSINAGKLARGDLNDCFIPCTPKGCLELIKETGVPIAGRHAVVVGRSKIVGAPMHDLLLWNNATVTTCHSKTAHLDEEVNKGDILVVATGQPEMVKGEWIKPGAIVIDCGINYVPDDKKPNGRKVVGDVAYDEAKERASFITPVPGGVGPMTVAMLMQSTVESAKRFLEKFKPGKWMIQYNNLNLKTPVPSDI... | 10-formyltetrahydrofolate biosynthetic process embryonic neurocranium morphogenesis embryonic viscerocranium morphogenesis heart development methionine biosynthetic process methionine metabolic process neural tube closure neutrophil homeostasis one-carbon metabolic process purine nucleotide biosynthetic process purine ... |
aerobic respiration cellular response to food cellular response to lipid cellular response to starvation cellular response to testosterone stimulus energy reserve metabolic process glucose homeostasis heat generation locomotor rhythm mitochondrion organization negative regulation of DNA-templated transcription negative... | cytosol; extracellular space; nucleus | insulin receptor activity odorant binding pheromone activity pheromone binding small molecule binding | Mus musculus | 3D-structure Disulfide bond Pheromone-binding Reference proteome Secreted Signal Transport | MKMLLLLCLG | MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEKHGILRENIIDLSNANRCLQARE | aerobic respiration cellular response to food cellular response to lipid cellular response to starvation cellular response to testosterone stimulus energy reserve metabolic process glucose homeostasis heat generation locomotor rhythm mitochondrion organization negative regulation of DNA-templated transcription negative... |
aerobic respiration cellular response to lipid energy reserve metabolic process glucose homeostasis heat generation locomotor rhythm mitochondrion organization negative regulation of DNA-templated transcription negative regulation of gluconeogenesis negative regulation of insulin secretion involved in cellular response... | cytosol; extracellular space; nucleus | insulin receptor activity odorant binding pheromone binding small molecule binding | Mus musculus | 3D-structure Disulfide bond Pheromone-binding Reference proteome Secreted Signal Transport | MKMLLLLCLG | MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLEKSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAKLCEEHGILRENIIDLSNANRCLQARE | aerobic respiration cellular response to lipid energy reserve metabolic process glucose homeostasis heat generation locomotor rhythm mitochondrion organization negative regulation of DNA-templated transcription negative regulation of gluconeogenesis negative regulation of insulin secretion involved in cellular response... |
aerobic respiration cellular response to lipid energy reserve metabolic process glucose homeostasis heat generation locomotor rhythm mitochondrion organization negative regulation of DNA-templated transcription negative regulation of gluconeogenesis negative regulation of insulin secretion involved in cellular response... | cytosol; extracellular space; nucleus | insulin receptor activity odorant binding pheromone binding small molecule binding | Mus musculus | 3D-structure Direct protein sequencing Disulfide bond Pheromone-binding Reference proteome Secreted Signal Transport | MKLLLCLGLT | MKLLLCLGLTLVCIHAEEATSKGQNLNVEKINGEWFSILLASDKREKIEEHGSMRVFVEHIHVLENSLAFKFHTVIDGECSEIFLVADKTEKAGEYSVMYDGFNTFTILKTDYDNYIMFHLINEKDGKTFQLMELYGRKADLNSDIKEKFVKLCEEHGIIKENIIDLTKTNRCLKARE | aerobic respiration cellular response to lipid energy reserve metabolic process glucose homeostasis heat generation locomotor rhythm mitochondrion organization negative regulation of DNA-templated transcription negative regulation of gluconeogenesis negative regulation of insulin secretion involved in cellular response... |
cholesterol homeostasis cholesterol metabolic process cholesterol transport high-density lipoprotein particle remodeling lipid homeostasis lipid transport low-density lipoprotein particle remodeling negative regulation of macrophage derived foam cell differentiation phosphatidylcholine metabolic process phospholipid ho... | extracellular exosome; extracellular region; extracellular space; high-density lipoprotein particle; vesicle | cholesterol binding cholesterol transfer activity lipid binding phosphatidylcholine binding phospholipid transporter activity triglyceride binding | Homo sapiens | 3D-structure Alternative splicing Atherosclerosis Cholesterol metabolism Direct protein sequencing Disease variant Disulfide bond Glycoprotein Lipid metabolism Lipid transport Reference proteome Secreted Signal Steroid metabolism Sterol metabolism Transport | MLAATVLTLA | MLAATVLTLALLGNAHACSKGTSHEAGIVCRITKPALLVLNHETAKVIQTAFQRASYPDITGEKAMMLLGQVKYGLHNIQISHLSIASSQVELVEAKSIDVSIQNVSVVFKGTLKYGYTTAWWLGIDQSIDFEIDSAIDLQINTQLTCDSGRVRTDAPDCYLSFHKLLLHLQGEREPGWIKQLFTNFISFTLKLVLKGQICKEINVISNIMADFVQTRAASILSDGDIGVDISLTGDPVITASYLESHHKGHFIYKNVSEDLPLPTFSPTLLGDSRMLYFWFSERVFHSLAKVAFQDGRLMLSLMGDEFKAVLETWGFNT... | cholesterol homeostasis cholesterol metabolic process cholesterol transport high-density lipoprotein particle remodeling lipid homeostasis lipid transport low-density lipoprotein particle remodeling negative regulation of macrophage derived foam cell differentiation phosphatidylcholine metabolic process phospholipid ho... |
adaptive immune response cellular response to interleukin-7 cellular response to nonylphenol cellular response to transforming growth factor beta stimulus cellular response to vitamin D circadian rhythm extrinsic apoptotic signaling pathway peptide antigen assembly with MHC class I protein complex platelet aggregation ... | acrosomal vesicle; apical plasma membrane; cell surface; endoplasmic reticulum; endoplasmic reticulum lumen; extracellular region; extracellular space; melanosome; MHC class I peptide loading complex; smooth endoplasmic reticulum; TAP complex; Tapasin-ERp57 complex | identical protein binding MHC class I protein binding peptidase activity protein disulfide isomerase activity protein-disulfide reductase (glutathione) activity protein-disulfide reductase activity | Rattus norvegicus | Acetylation Adaptive immunity Direct protein sequencing Disulfide bond Endoplasmic reticulum Immunity Isomerase Methylation Phosphoprotein Redox-active center Reference proteome Repeat Signal | MRFSCLALLP | MRFSCLALLPGVALLLASALLASASDVLELTDENFESRVSDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQAGPASVPLRTEDEFKKFISDKDASVVGFFRDLFSDGHSEFLKAASNLRDNYRFAHTNVESLVKEYDDNGEGITIFRPLHLANKFEDKIVAYTEKKMTSGKIKKFIQESIFGLCPHMTEDNKDLIQGKDLLTAYYDVDYEKNTKGSNYWRNRVMMVAKTFLDAGHKLNFAVASRKTFSHELSDFGLESTT... | adaptive immune response cellular response to interleukin-7 cellular response to nonylphenol cellular response to transforming growth factor beta stimulus cellular response to vitamin D circadian rhythm extrinsic apoptotic signaling pathway peptide antigen assembly with MHC class I protein complex platelet aggregation ... |
cholesterol homeostasis chylomicron remodeling fatty acid biosynthetic process fatty acid metabolic process low-density lipoprotein particle mediated signaling positive regulation of adipose tissue development positive regulation of chemokine production positive regulation of cholesterol storage positive regulation of ... | catalytic complex; chylomicron; extracellular space; plasma membrane; very-low-density lipoprotein particle | 1-acyl-2-lysophosphatidylserine acylhydrolase activity apolipoprotein binding calcium ion binding heparan sulfate proteoglycan binding heparin binding lipoprotein lipase activity lipoprotein particle binding phosphatidylserine 1-acylhydrolase activity phospholipase A1 activity phospholipase activity protein homodimeriz... | Gallus gallus | Calcium Cell membrane Chylomicron Disulfide bond Extracellular matrix Glycoprotein Heparin-binding Hydrolase Lipid degradation Lipid metabolism Membrane Metal-binding Nitration Reference proteome Secreted Signal VLDL | MERGRGMGKT | MERGRGMGKTALLAVLCLCLRGAAGSDPEAEMNFEGIESKFSLRTPAEPDEDVCYLVPGQMDSLAQCNFNHTSKTFVVIHGWTVTGMYESWVPKLVDALYKREPDSNVIVVDWLVRAQQHYPVSAAYTKLVGKDVAMFIDWMEEKFNYPLNNVHLLGYSLGAHAAGIAGSLTKKKVNRITGLDPAGPTFEYADAPIRLSPDDADFVDVLHTYTRGSPDRSIGIQKPVGHIDIYPNGGGFQPGCNLGEALRLIAEKGFSDVDQLVKCSHERSIHLFIDSLLYEEKPSMAYRCNTKEAFEKGLCLSCRKNRCNNLGYKVNRV... | cholesterol homeostasis chylomicron remodeling fatty acid biosynthetic process fatty acid metabolic process low-density lipoprotein particle mediated signaling positive regulation of adipose tissue development positive regulation of chemokine production positive regulation of cholesterol storage positive regulation of ... |
antigen processing and presentation antigen processing and presentation, endogenous lipid antigen via MHC class Ib antigen processing and presentation, exogenous lipid antigen via MHC class Ib immune response innate immune response NK T cell differentiation positive regulation of interleukin-2 production positive regul... | cell surface; cytoplasm; early endosome; endoplasmic reticulum; endosome membrane; external side of plasma membrane; extracellular space; late endosome; lysosomal membrane; lysosome | cell adhesion molecule binding endogenous lipid antigen binding exogenous lipid antigen binding histone binding lipid antigen binding lipopeptide binding T cell receptor binding | Mus musculus | 3D-structure Cell membrane Disulfide bond Endosome Glycoprotein Immunity Immunoglobulin domain Innate immunity Lysosome Membrane Reference proteome Signal Transmembrane Transmembrane helix | MRYLPWLLLW | MRYLPWLLLWAFLQVWGQSEAQQKNYTFRCLQMSSFANRSWSRTDSVVWLGDLQTHRWSNDSATISFTKPWSQGKLSNQQWEKLQHMFQVYRVSFTRDIQELVKMMSPKEDYPIEIQLSAGCEMYPGNASESFLHVAFQGKYVVRFWGTSWQTVPGAPSWLDLPIKVLNADQGTSATVQMLLNDTCPLFVRGLLEAGKSDLEKQEKPVAWLSSVPSSADGHRQLVCHVSGFYPKPVWVMWMRGDQEQQGTHRGDFLPNADETWYLQATLDVEAGEEAGLACRVKHSSLGGQDIILYWDARQAPVGLIVFIVLIMLVVVGA... | antigen processing and presentation antigen processing and presentation, endogenous lipid antigen via MHC class Ib antigen processing and presentation, exogenous lipid antigen via MHC class Ib immune response innate immune response NK T cell differentiation positive regulation of interleukin-2 production positive regul... |
antigen processing and presentation, endogenous lipid antigen via MHC class Ib antigen processing and presentation, exogenous lipid antigen via MHC class Ib immune response innate immune response positive regulation of interleukin-2 production positive regulation of interleukin-4 production positive regulation of NK T ... | cell surface; cytoplasm; endoplasmic reticulum; endosome membrane; external side of plasma membrane; extracellular space; lysosomal membrane; lysosome | cell adhesion molecule binding endogenous lipid antigen binding exogenous lipid antigen binding histone binding lipid antigen binding lipopeptide binding | Mus musculus | 3D-structure Cell membrane Disulfide bond Endosome Glycoprotein Immunity Immunoglobulin domain Innate immunity Lysosome Membrane Reference proteome Signal Transmembrane Transmembrane helix | MRYLPCLLLW | MRYLPCLLLWAFLQVWGQSEVQQKNYTFRCLQTSSFANISWSRTDSLILLGDLQTHRWSNDSATISFTKPWSQGKLSNQQWEKLQHMFQVYRVSFTRDIQELVKMMSPKEDYPIEIQLSTGCEMYPGNASESFFHVAFQGKYAVRFRGTSWQRVLGAPSWLDLPIKVLNADQGTSATVQTLLNDTWPQFARGLLEAGKSDLEKQEKPVAWLSSVPSSAHGHLQLVCHVSGFYPKPVWVMWMRGDQEQQGTHRGDFLPNADETWYLQATLDVEAGEEAGLACRVKHSSLGGQDIILYWDARQAPVGLIVFIVLIMLVVVGA... | antigen processing and presentation, endogenous lipid antigen via MHC class Ib antigen processing and presentation, exogenous lipid antigen via MHC class Ib immune response innate immune response positive regulation of interleukin-2 production positive regulation of interleukin-4 production positive regulation of NK T ... |
angiogenesis calcium-mediated signaling cell adhesion cell chemotaxis immune response negative regulation of cell population proliferation negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage oculomotor nerve development positive regulation of cytosolic calcium ion concentration positi... | cell surface; clathrin-coated pit; early endosome; endosome; external side of plasma membrane; plasma membrane; recycling endosome | C-C chemokine binding C-C chemokine receptor activity C-X-C chemokine binding C-X-C chemokine receptor activity coreceptor activity scavenger receptor activity | Canis lupus familiaris | Cell adhesion Cell membrane Developmental protein Disulfide bond Endosome G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix Ubl conjugation | MDLHLFDYAE | MDLHLFDYAEPGNFSDISWPCNSSDCIVVDTVLCPNMPNKSVLLYTLSFIYIFIFVIGMIANSVVVWVNIQAKTTGYDTHCYILNLAIADLWVVVTIPVWVVSLVQHNQWPMGELTCKITHLIFSINLFGSIFFLTCMSVDRYLSITYFASTSSRRKKVVRRAVCVLVWLLAFCVSLPDTYYLKTVTSASNNETYCRSFYPEHSVKEWLISMELVSVVLGFAIPFCVIAVFYCLLARAISASSDQEKQSSRKIIFSYVVVFLVCWLPYHVVVLLDIFSILHYIPFTCQLENFLFTALHVTQCLSLVHCCVNPVLYSFINR... | angiogenesis calcium-mediated signaling cell adhesion cell chemotaxis immune response negative regulation of cell population proliferation negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage oculomotor nerve development positive regulation of cytosolic calcium ion concentration positi... |
adenylate cyclase-activating G protein-coupled receptor signaling pathway apoptotic signaling pathway eating behavior G protein-coupled adenosine receptor signaling pathway inhibitory postsynaptic potential locomotory behavior negative regulation of alpha-beta T cell activation negative regulation of inflammatory respo... | plasma membrane; postsynapse | calmodulin binding enzyme binding G protein-coupled adenosine receptor activity identical protein binding lipid binding | Canis lupus familiaris | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Transducer Transmembrane Transmembrane helix Ubl conjugation | MSTMGSWVYI | MSTMGSWVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHNCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAVCWVLSFAIGLTPMLGWNNCSQPKEGRNYSQGCGEGQVACLFEDVVPMNYMVYYNFFAFVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPECSHAPLWLMYLTIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRRREPFKAGGTS... | adenylate cyclase-activating G protein-coupled receptor signaling pathway apoptotic signaling pathway eating behavior G protein-coupled adenosine receptor signaling pathway inhibitory postsynaptic potential locomotory behavior negative regulation of alpha-beta T cell activation negative regulation of inflammatory respo... |
autophagosome assembly endoplasmic reticulum to Golgi vesicle-mediated transport intracellular protein transport | cytosol; endomembrane system; endoplasmic reticulum membrane; Golgi membrane; nucleus; phagophore assembly site membrane | GTP binding GTPase activity | Schizosaccharomyces pombe | Autophagy Cytoplasm Endoplasmic reticulum Golgi apparatus GTP-binding Lipoprotein Membrane Nucleotide-binding Phosphoprotein Prenylation Protein transport Reference proteome Transport | MNPEYDYLFK | MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTFELEGKTVKLQIWDTAGQERFRTITSSYYRGAHGIIIVYDVTDQDSFNNVKQWLQEIDRYAVEGVNRLLVGNKSDMVDKKVVEYSVAKEFADSLNIPFLETSAKDSTNVEQAFLTMSRQIKERMGNNTFASSNAKSSVKVGQGTNVSQSSSNCC | autophagosome assembly endoplasmic reticulum to Golgi vesicle-mediated transport intracellular protein transport cytosol; endomembrane system; endoplasmic reticulum membrane; Golgi membrane; nucleus; phagophore assembly site membrane GTP binding GTPase activity Schizosaccharomyces pombe Autophagy Cytoplasm Endoplasmic... |
chromatin organization chromatin remodeling DNA repair maintenance of transcriptional fidelity during transcription elongation by RNA polymerase III negative regulation of DNA binding protein-DNA complex assembly RNA polymerase II preinitiation complex assembly RNA polymerase III preinitiation complex assembly | chromosome; nucleus; protein-DNA complex | DNA binding, bending MutSalpha complex binding nucleic acid binding nucleosome binding | Saccharomyces cerevisiae | 3D-structure Chromosome DNA damage DNA repair DNA-binding Nucleus Reference proteome Transcription Transcription regulation | MVTPREPKKR | MVTPREPKKRTTRKKKDPNAPKRALSAYMFFANENRDIVRSENPDITFGQVGKKLGEKWKALTPEEKQPYEAKAQADKKRYESEKELYNATLA | chromatin organization chromatin remodeling DNA repair maintenance of transcriptional fidelity during transcription elongation by RNA polymerase III negative regulation of DNA binding protein-DNA complex assembly RNA polymerase II preinitiation complex assembly RNA polymerase III preinitiation complex assembly chromoso... |
chromatin remodeling DNA repair maintenance of transcriptional fidelity during transcription elongation by RNA polymerase III RNA polymerase III preinitiation complex assembly transcription by RNA polymerase II | chromosome; nucleus | DNA binding, bending sequence-specific DNA binding | Saccharomyces cerevisiae | Chromosome DNA damage DNA repair DNA-binding Nucleus Reference proteome Transcription Transcription regulation | MAATKEAKQP | MAATKEAKQPKEPKKRTTRRKKDPNAPKRGLSAYMFFANENRDIVRSENPDVTFGQVGRILGERWKALTAEEKQPYESKAQADKKRYESEKELYNATRA | chromatin remodeling DNA repair maintenance of transcriptional fidelity during transcription elongation by RNA polymerase III RNA polymerase III preinitiation complex assembly transcription by RNA polymerase II chromosome; nucleus DNA binding, bending sequence-specific DNA binding Saccharomyces cerevisiae Chromosome D... |
protein secretion regulation of COPII vesicle coating vesicle-mediated transport | endoplasmic reticulum; endoplasmic reticulum membrane; Golgi apparatus | GTPase activator activity guanyl-nucleotide exchange factor activity | Saccharomyces cerevisiae | 3D-structure Endoplasmic reticulum ER-Golgi transport Glycoprotein Golgi apparatus GTPase activation Membrane Protein transport Reference proteome Repeat Signal-anchor Transmembrane Transmembrane helix Transport WD repeat | MKFVTASYNV | MKFVTASYNVGYPAYGAKFLNNDTLLVAGGGGEGNNGIPNKLTVLRVDPTKDTEKEQFHILSEFALEDNDDSPTAIDASKGIILVGCNENSTKITQGKGNKHLRKFKYDKVNDQLEFLTSVDFDASTNADDYTKLVYISREGTVAAIASSKVPAIMRIIDPSDLTEKFEIETRGEVKDLHFSTDGKVVAYITGSSLEVISTVTGSCIARKTDFDKNWSLSKINFIADDTVLIAASLKKGKGIVLTKISIKSGNTSVLRSKQVTNRFKGITSMDVDMKGELAVLASNDNSIALVKLKDLSMSKIFKQAHSFAITEVTISPD... | protein secretion regulation of COPII vesicle coating vesicle-mediated transport endoplasmic reticulum; endoplasmic reticulum membrane; Golgi apparatus GTPase activator activity guanyl-nucleotide exchange factor activity Saccharomyces cerevisiae 3D-structure Endoplasmic reticulum ER-Golgi transport Glycoprotein Golgi ... |
amino acid transport L-arginine transmembrane transport | plasma membrane | amino acid transmembrane transporter activity L-arginine transmembrane transporter activity | Escherichia coli | Amino-acid transport Cell inner membrane Cell membrane Membrane Reference proteome Transmembrane Transmembrane helix Transport | MFSYYFQGLA | MFSYYFQGLALGAAMILPLGPQNAFVMNQGIRRQYHIMIALLCAISDLVLICAGIFGGSALLMQSPWLLALVTWGGVAFLLWYGFGAFKTAMSSNIELASAEVMKQGRWKIIATMLAVTWLNPHVYLDTFVVLGSLGGQLDVEPKRWFALGTISASFLWFFGLALLAAWLAPRLRTAKAQRIINLVVGCVMWFIALQLARDGIAHAQALFS | amino acid transport L-arginine transmembrane transport plasma membrane amino acid transmembrane transporter activity L-arginine transmembrane transporter activity Escherichia coli Amino-acid transport Cell inner membrane Cell membrane Membrane Reference proteome Transmembrane Transmembrane helix Transport MFSYYFQGLA M... |
cellular response to hydrogen peroxide defense response to bacterium extrinsic apoptotic signaling pathway in absence of ligand innate immune response long-term memory negative regulation of hippocampal neuron apoptotic process positive regulation of apoptotic process positive regulation of cell projection organization... | cytoplasmic vesicle lumen; cytosol; extracellular region; extracellular space | enterobactin binding identical protein binding iron ion binding iron ion sequestering activity protease binding small molecule binding | Mus musculus | 3D-structure Apoptosis Cytoplasmic vesicle Direct protein sequencing Disulfide bond Glycoprotein Immunity Innate immunity Ion transport Iron Iron transport Pyrrolidone carboxylic acid Reference proteome Secreted Signal Transport | MALSVMCLGL | MALSVMCLGLALLGVLQSQAQDSTQNLIPAPSLLTVPLQPDFRSDQFRGRWYVVGLAGNAVQKKTEGSFTMYSTIYELQENNSYNVTSILVRDQDQGCRYWIRTFVPSSRAGQFTLGNMHRYPQVQSYNVQVATTDYNQFAMVFFRKTSENKQYFKITLYGRTKELSPELKERFTRFAKSLGLKDDNIIFSVPTDQCIDN | cellular response to hydrogen peroxide defense response to bacterium extrinsic apoptotic signaling pathway in absence of ligand innate immune response long-term memory negative regulation of hippocampal neuron apoptotic process positive regulation of apoptotic process positive regulation of cell projection organization... |
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