Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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autophagy carbohydrate metabolic process filamentous growth peroxisome organization positive regulation of gluconeogenesis regulation of cellular response to glucose starvation regulation of invasive growth in response to glucose limitation regulation of transcription by RNA polymerase II | cytoplasm; cytosol; nuclear envelope lumen; nucleotide-activated protein kinase complex; nucleus; plasma membrane | AMP binding ATP binding identical protein binding protein kinase binding protein kinase regulator activity protein serine/threonine kinase activator activity | Saccharomyces cerevisiae | 3D-structure ATP-binding Carbohydrate metabolism CBS domain Cytoplasm Direct protein sequencing Nucleotide-binding Nucleus Reference proteome Repeat Transcription Transcription regulation | MKPTQDSQEK | MKPTQDSQEKVSIEQQLAVESIRKFLNSKTSYDVLPVSYRLIVLDTSLLVKKSLNVLLQNSIVSAPLWDSKTSRFAGLLTTTDFINVIQYYFSNPDKFELVDKLQLDGLKDIERALGVDQLDTASIHPSRPLFEACLKMLESRSGRIPLIDQDEETHREIVVSVLTQYRILKFVALNCRETHFLKIPIGDLNIITQDNMKSCQMTTPVIDVIQMLTQGRVSSVPIIDENGYLINVYEAYDVLGLIKGGIYNDLSLSVGEALMRRSDDFEGVYTCTKNDKLSTIMDNIRKARVHRFFVVDDVGRLVGVLTLSDILKYILLG... | autophagy carbohydrate metabolic process filamentous growth peroxisome organization positive regulation of gluconeogenesis regulation of cellular response to glucose starvation regulation of invasive growth in response to glucose limitation regulation of transcription by RNA polymerase II cytoplasm; cytosol; nuclear en... |
viral entry into host cell viral penetration into host nucleus | host cell endoplasmic reticulum membrane; host cell nucleus; membrane; viral capsid | DNA binding structural molecule activity | Murine polyomavirus | 3D-structure Alternative initiation Alternative splicing Capsid protein DNA-binding Host endoplasmic reticulum Host membrane Host nucleus Late protein Lipoprotein Membrane Myristate Transmembrane Transmembrane helix Viral penetration into host nucleus Virion Virus entry into host cell | MGAALTILVD | MGAALTILVDLIEGLAEVSTLTGLSAEAILSGEALAALDGEITALTLEGVMSSETALATMGISEEVYGFVSTVPVFVNRTAGAIWLMQTVQGASTISLGIQRYLHNEEVPTVNRNMALIPWRDPALLDIYFPGVNQFAHALNVVHDWGHGLLHSVGRYVWQMVVQETQHRLEGAVRELTVRQTHTFLDGLARLLENTRWVVSNAPQSAIDAINRGASSASSGYSSLSDYYRQLGLNPPQRRALFNRIEGSMGNGGPTPAAHIQDESGEVIKFYQAQVVSHQRVTPDWMLPLILGLYGDITPTWATVIEEDGPQKKKRRL | viral entry into host cell viral penetration into host nucleus host cell endoplasmic reticulum membrane; host cell nucleus; membrane; viral capsid DNA binding structural molecule activity Murine polyomavirus 3D-structure Alternative initiation Alternative splicing Capsid protein DNA-binding Host endoplasmic reticulum ... |
cellular response to epinephrine stimulus cellular response to insulin stimulus glycolytic process phosphorylation pyruvate biosynthetic process response to ATP response to cAMP response to glucose response to hypoxia response to metal ion response to nutrient response to other organism | cytoplasm; cytosol; plasma membrane | ATP binding kinase activity magnesium ion binding monosaccharide binding potassium ion binding pyruvate kinase activity | Rattus norvegicus | 3D-structure Allosteric enzyme Alternative splicing ATP-binding Glycolysis Kinase Magnesium Manganese Metal-binding Nucleotide-binding Phosphoprotein Potassium Pyruvate Reference proteome Transferase | MSVQENTLPQ | MSVQENTLPQQLWPWIFRSQKDLAKSALSGAPGGPAGYLRRASVAQLTQELGTAFFQQQQLPAAMADTFLEHLCLLDIDSQPVAARSTSIIATIGPASRSVDRLKEMIKAGMNIARLNFSHGSHEYHAESIANIREATESFATSPLSYRPVAIALDTKGPEIRTGVLQGGPESEVEIVKGSQVLVTVDPKFQTRGDAKTVWVDYHNITRVVAVGGRIYIDDGLISLVVQKIGPEGLVTEVEHGGILGSRKGVNLPNTEVDLPGLSEQDLLDLRFGVQHNVDIIFASFVRKASDVLAVRDALGPEGQNIKIISKIENHEGV... | cellular response to epinephrine stimulus cellular response to insulin stimulus glycolytic process phosphorylation pyruvate biosynthetic process response to ATP response to cAMP response to glucose response to hypoxia response to metal ion response to nutrient response to other organism cytoplasm; cytosol; plasma membr... |
arachidonic acid metabolic process liver development xenobiotic metabolic process | cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle | aromatase activity heme binding iron ion binding monooxygenase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | Rattus norvegicus | Endoplasmic reticulum Heme Iron Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Reference proteome | MELLAGTGLW | MELLAGTGLWPMAIFTVIFILLVDLMHRRQRWTSRYPPGPVPWPVLGNLLQVDLCNMPYSMYKLQNRYGDVFSLQMGWKPVVVINGLKAVQELLVTCGEDTADRPEMPIFQHIGYGHKAKGVVLAPYGPEWREQRRFSVSTLRNFGVGKKSLEQWVTDEASHLCDALTAEAGRPLDPYTLLNKAVCNVIASLIYARRFDYGDPDFIKVLKILKESMGEQTGLFPEVLNMFPVLLRIPGLADKVFPGQKTFLTMVDNLVTEHKKTWDPDQPPRDLTDAFLAEIEKAKGNPESSFNDANLRLVVNDLFGAGMVTTSITLTWA... | arachidonic acid metabolic process liver development xenobiotic metabolic process cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle aromatase activity heme binding iron ion binding monooxygenase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction ... |
arachidonic acid metabolic process xenobiotic metabolic process | cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle | aromatase activity heme binding iron ion binding monooxygenase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | Rattus norvegicus | Endoplasmic reticulum Glycoprotein Heme Iron Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Reference proteome | MELLNGTGLW | MELLNGTGLWPMAIFTVIFILLVDLMHRHQRWTSRYPPGPVPWPVLGNLLQVDPSNMPYSMYKLQHRYGDVFSLQMGWKPMVIVNRLKAVQEVLVTHGEDTADRPPVPIFKCLGVKPRSQGVVFASYGPEWREQRRFSVSTLRTFGMGKKSLEEWVTKEAGHLCDAFTAQNGRSINPKAMLNKALCNVIASLIFARRFEYEDPYLIRMLTLVEESLIEVSGFIPEVLNTFPALLRIPGLADKVFQGQKTFMAFLDNLLAENRTTWDPAQPPRNLTDAFLAEVEKAKGNPESSFNDENLRMVVVDLFTAGMVTTATTLTWA... | arachidonic acid metabolic process xenobiotic metabolic process cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle aromatase activity heme binding iron ion binding monooxygenase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge... |
N-terminal protein amino acid acetylation | cytoplasm; mitochondrion; NatA complex | ribosome binding | Saccharomyces cerevisiae | 3D-structure Acetylation Coiled coil Cytoplasm Direct protein sequencing Phosphoprotein Reference proteome Repeat TPR repeat | MSRKRSTKPK | MSRKRSTKPKPAAKIALKKENDQFLEALKLYEGKQYKKSLKLLDAILKKDGSHVDSLALKGLDLYSVGEKDDAASYVANAIRKIEGASASPICCHVLGIYMRNTKEYKESIKWFTAALNNGSTNKQIYRDLATLQSQIGDFKNALVSRKKYWEAFLGYRANWTSLAVAQDVNGERQQAINTLSQFEKLAEGKISDSEKYEHSECLMYKNDIMYKAASDNQDKLQNVLKHLNDIEPCVFDKFGLLERKATIYMKLGQLKDASIVYRTLIKRNPDNFKYYKLLEVSLGIQGDNKLKKALYGKLEQFYPRCEPPKFIPLTFLQ... | N-terminal protein amino acid acetylation cytoplasm; mitochondrion; NatA complex ribosome binding Saccharomyces cerevisiae 3D-structure Acetylation Coiled coil Cytoplasm Direct protein sequencing Phosphoprotein Reference proteome Repeat TPR repeat MSRKRSTKPK MSRKRSTKPKPAAKIALKKENDQFLEALKLYEGKQYKKSLKLLDAILKKDGSHVDSLALK... |
heme A biosynthetic process | plasma membrane | metal ion binding oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor | Bacillus subtilis | 3D-structure Cell membrane Direct protein sequencing Heme biosynthesis Iron Membrane Metal-binding Oxidoreductase Reference proteome Transmembrane Transmembrane helix | MNKALKALGV | MNKALKALGVLTTFVMLIVLIGGALVTKTGSGQGCGRQWPLCHGRFFPELNPASIIEWSHRFASGISIILVLSLAFWSWRKITPIFRETTFLAIMSIIFLFLQALLGALAVVFGSNALIMALHFGISLISFASVLILTLLIFEADKSVRTLVKPLQIGKKMQFHMIGILIYSYIVVYTGAYVRHTESSLACPNVPLCSPLNNGLPTQFHEWVQMGHRAAALLLFVWIIVAAVHAITSYKDQKQIFWGWISCLIFITLQALSGIMIVYSELALGFALAHSFFIACLFGVLCYFLLLIARFRYESRQS | heme A biosynthetic process plasma membrane metal ion binding oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor Bacillus subtilis 3D-structure Cell membrane Direct protein sequencing Heme biosynthesis Iron Membrane Metal-binding Oxidoreductase Reference proteome Transmembrane Transmembrane helix MNKA... |
amino acid metabolic process collagen catabolic process negative regulation of programmed cell death proteolysis | extracellular exosome | manganese ion binding metalloaminopeptidase activity metallocarboxypeptidase activity peptidase activity proline dipeptidase activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Collagen degradation Dipeptidase Direct protein sequencing Disease variant Hydrolase Manganese Metal-binding Metalloprotease Phosphoprotein Protease Reference proteome | MAAATGPSFW | MAAATGPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAM... | amino acid metabolic process collagen catabolic process negative regulation of programmed cell death proteolysis extracellular exosome manganese ion binding metalloaminopeptidase activity metallocarboxypeptidase activity peptidase activity proline dipeptidase activity Homo sapiens 3D-structure Acetylation Alternative s... |
activation of innate immune response cellular hyperosmotic salinity response cellular response to gamma radiation cellular response to X-ray DNA ligation double-strand break repair via classical nonhomologous end joining double-strand break repair via nonhomologous end joining innate immune response negative regulation... | chromosome, telomeric region; cytosol; DNA-dependent protein kinase complex; DNA-dependent protein kinase-DNA ligase 4 complex; extracellular region; ficolin-1-rich granule lumen; Ku70:Ku80 complex; membrane; nonhomologous end joining complex; nuclear telomere cap complex; nucleolus; nucleoplasm; nucleus; protein-conta... | 5'-deoxyribose-5-phosphate lyase activity ATP binding ATP hydrolysis activity ATP-dependent activity, acting on DNA cyclin binding damaged DNA binding DNA binding DNA helicase activity double-stranded DNA binding protein-containing complex binding RNA binding scaffold protein binding telomeric DNA binding transcription... | Homo sapiens | 3D-structure Acetylation Activator ADP-ribosylation Alternative splicing ATP-binding Chromosome Direct protein sequencing DNA damage DNA recombination DNA repair DNA-binding Helicase Host-virus interaction Hydrolase Immunity Innate immunity Isopeptide bond Lyase Multifunctional enzyme Nucleotide-binding Nucleus Phospho... | MSGWESYYKT | MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPFDMSIQCIQSVYISKIISSDRDLLAVVFYGTEKDKNSVNFKNIYVLQELDNPGAKRILELDQFKGQQGQKRFQDMMGHGSDYSLSEVLWVCANLFSDVQFKMSHKRIMLFTNEDNPHGNDSAKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYRDIISIAEDEDLRVHFEESSKLEDLLRKVRAKETRKRALSRLKLKLNKDIVISVGIYNLVQKALKPPPIKLYRETNEPVKTKTRTFNTSTGGLLLPSDTKRSQ... | activation of innate immune response cellular hyperosmotic salinity response cellular response to gamma radiation cellular response to X-ray DNA ligation double-strand break repair via classical nonhomologous end joining double-strand break repair via nonhomologous end joining innate immune response negative regulation... |
actin filament bundle assembly angiogenesis muscle contraction negative regulation of calcium-dependent ATPase activity | actin cytoskeleton; myofibril; stress fiber | actin binding calmodulin binding myosin binding myosin II binding S100 protein binding | Gallus gallus | Actin-binding Alternative splicing Calmodulin-binding Cytoplasm Cytoskeleton Direct protein sequencing Muscle protein Phosphoprotein Reference proteome Repeat | MDDFERRREL | MDDFERRRELRRQKREEMRLEAERLSYQRNDDDEEEAARERRRRARQERLRQKEEGDVSGEVTEKSEVNAQNSVAEEETKRSTDDEAALLERLARREERRQKRLQEALERQKEFDPTITDGSLSVPSRREVNNVEENEITGKEEKVETRQGRCEIEETETVTKSYQRNNWRQDGEEEGKKEEKDSEEEKPKEVPTEENQVDVAVEKSTDKEEVVETKTLAVNAENDTNAMLEGEQSITDAADKEKEEAEKEREKLEAEEKERLKAEEEKKAAEEKQKAEEEKKAAEERERAKAEEEKRAAEERERAKAEEERKAAEERER... | actin filament bundle assembly angiogenesis muscle contraction negative regulation of calcium-dependent ATPase activity actin cytoskeleton; myofibril; stress fiber actin binding calmodulin binding myosin binding myosin II binding S100 protein binding Gallus gallus Actin-binding Alternative splicing Calmodulin-binding C... |
axon guidance brain development cell-cell adhesion central nervous system myelin formation cerebellum development gene expression locomotory behavior myelination neuron projection development Notch signaling pathway positive regulation of gene expression positive regulation of neuron projection development positive reg... | axon; myelin sheath; plasma membrane; postsynaptic membrane; presynaptic membrane; side of membrane | carbohydrate binding cell-cell adhesion mediator activity | Mus musculus | 3D-structure Cell adhesion Cell membrane Direct protein sequencing Disulfide bond Glycoprotein GPI-anchor Immunoglobulin domain Lipoprotein Membrane Notch signaling pathway Reference proteome Repeat Signal | MKMPLLVSHL | MKMPLLVSHLLLISLTSCLGDFTWHRRYGHGVSEEDKGFGPIFEEQPINTIYPEESLEGKVSLNCRARASPFPVYKWRMNNGDVDLTNDRYSMVGGNLVINNPDKQKDAGVYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVKVKEGKGMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVESSDRGNYSCFVSSPSITKSVFSKFIPLIPIPERTTKPYPADIVVQFKDIYTMMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTSGAVLKIFNIQLEDEGLYECEAENIRGKDK... | axon guidance brain development cell-cell adhesion central nervous system myelin formation cerebellum development gene expression locomotory behavior myelination neuron projection development Notch signaling pathway positive regulation of gene expression positive regulation of neuron projection development positive reg... |
intracellular protein transport neuropeptide signaling pathway peptide hormone processing regulation of hormone secretion | extracellular region; nucleus; secretory granule | enzyme inhibitor activity enzyme regulator activity unfolded protein binding | Mus musculus | Chaperone Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Neuropeptide Phosphoprotein Reference proteome Secreted Signal Sulfation Transport | MASRLVSAML | MASRLVSAMLSGLLFWLMFEWNPAFAYSPRTPDRVSETDIQRLLHGVMEQLGIARPRVEYPAHQAMNLVGPQSIEGGAHEGLQHLGPFGNIPNIVAELTGDNIPKDFSEDQGYPDPPNPCPLGKTADDGCLENAPDTAEFSREFQLDQHLFDPEHDYPGLGKWNKKLLYEKMKGGQRRKRRSVNPYLQGKRLDNVVAKKSVPHFSEEEKEAE | intracellular protein transport neuropeptide signaling pathway peptide hormone processing regulation of hormone secretion extracellular region; nucleus; secretory granule enzyme inhibitor activity enzyme regulator activity unfolded protein binding Mus musculus Chaperone Cleavage on pair of basic residues Direct protein... |
negative regulation of translation positive regulation of cytoplasmic mRNA processing body assembly positive regulation of translation | cytoplasm; mRNA cap binding complex | eukaryotic initiation factor 4E binding translation initiation factor activity | Saccharomyces cerevisiae | 3D-structure Cytoplasm Initiation factor Phosphoprotein Protein biosynthesis Protein synthesis inhibitor Reference proteome Translation regulation | MIKYTIDELF | MIKYTIDELFQLKPSLTLEVNFDAVEFRAIIEKVKQLQHLKEEEFNSHHVGHFGRRRSSHHHGRPKIKHNKPKVTTDSDGWCTFEAKKKGSGEDDEEETETTPTSTVPVATIAQETLKVKPNNKNISSNRPADTRDIVADKPILGFNAFAALESEDEDDEA | negative regulation of translation positive regulation of cytoplasmic mRNA processing body assembly positive regulation of translation cytoplasm; mRNA cap binding complex eukaryotic initiation factor 4E binding translation initiation factor activity Saccharomyces cerevisiae 3D-structure Cytoplasm Initiation factor Pho... |
adenylate cyclase-activating G protein-coupled receptor signaling pathway amylin receptor signaling pathway amyloid fibril formation bone resorption eating behavior negative regulation of bone resorption negative regulation of cell population proliferation negative regulation of osteoclast differentiation osteoclast di... | cytosol; extracellular space; inclusion body | hormone activity identical protein binding lipid binding receptor ligand activity signaling receptor binding | Mus musculus | Amidation Amyloid Cleavage on pair of basic residues Disulfide bond Hormone Reference proteome Secreted Signal | MMCISKLPAV | MMCISKLPAVLLILSVALNHLRATPVRSGSNPQMDKRKCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTYGKRNAAGDPNRESLDFLLV | adenylate cyclase-activating G protein-coupled receptor signaling pathway amylin receptor signaling pathway amyloid fibril formation bone resorption eating behavior negative regulation of bone resorption negative regulation of cell population proliferation negative regulation of osteoclast differentiation osteoclast di... |
amylin receptor signaling pathway bone resorption eating behavior glucose metabolic process negative regulation of bone resorption negative regulation of osteoclast differentiation osteoclast differentiation positive regulation of calcium-mediated signaling positive regulation of cAMP-mediated signaling positive regula... | extracellular space; neuronal cell body; secretory granule | hormone activity identical protein binding lipid binding receptor ligand activity signaling receptor binding | Rattus norvegicus | 3D-structure Amidation Amyloid Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Hormone Reference proteome Secreted Signal | MRCISRLPAV | MRCISRLPAVLLILSVALGHLRATPVGSGTNPQVDKRKCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTYGKRNVAEDPNRESLDFLLL | amylin receptor signaling pathway bone resorption eating behavior glucose metabolic process negative regulation of bone resorption negative regulation of osteoclast differentiation osteoclast differentiation positive regulation of calcium-mediated signaling positive regulation of cAMP-mediated signaling positive regula... |
cytoplasmic translation maturation of LSU-rRNA translation at postsynapse translation at presynapse | cytoplasm; cytosol; cytosolic large ribosomal subunit; cytosolic ribosome; membrane; nucleolus; polysomal ribosome; postsynapse; presynapse; ribosome; synapse | RNA binding structural constituent of ribosome | Mus musculus | 3D-structure Acetylation Cytoplasm Isopeptide bond Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation | MPKGKKAKGK | MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGHLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG | cytoplasmic translation maturation of LSU-rRNA translation at postsynapse translation at presynapse cytoplasm; cytosol; cytosolic large ribosomal subunit; cytosolic ribosome; membrane; nucleolus; polysomal ribosome; postsynapse; presynapse; ribosome; synapse RNA binding structural constituent of ribosome Mus musculus 3... |
DNA-templated viral transcription modulation by virus of host transcription perturbation by virus of host cell cycle progression positive regulation of DNA-templated transcription suppression by virus of host translation initiation suppression by virus of host type I interferon-mediated signaling pathway | host cell nuclear matrix; host cell nucleus | protein serine/threonine phosphatase inhibitor activity | Epstein-Barr virus | 3D-structure Activator Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Modulation of host cell cycle by virus Modulation of host PP1 activity by virus Phosphoprotein Reference proteome Repeat Transcription Transcription regu... | MPTFYLALHG | MPTFYLALHGGQTYHLIVDTDSLGNPSLSVIPSNPYQEQLSDTPLIPLTIFVGENTGVPPPLPPPPPPPPPPPPPPPPPPPPPPPPPPSPPPPPPPPPPPQRRDAWTQEPSPLDRDPLGYDVGHGPLASAMRMLWMANYIVRQSRGDRGLILPQGPQTAPQARLVQPHVPPLRPTAPTILSPLSQPRLTPPQPLMMPPRPTPPTPLPPATLTVPPRPTRPTTLPPTPLLTVLQRPTELQPTPSPPRMHLPVLHVPDQSMHPLTHQSTPNDPDSPEPRSPTVFYNIPPMPLPPSQLPPPAAPAQPPPGVINDQQLHHLPSG... | DNA-templated viral transcription modulation by virus of host transcription perturbation by virus of host cell cycle progression positive regulation of DNA-templated transcription suppression by virus of host translation initiation suppression by virus of host type I interferon-mediated signaling pathway host cell nucl... |
B cell differentiation blood vessel maturation definitive hemopoiesis positive regulation of DNA-templated transcription regulation of DNA-templated transcription regulation of transcription by RNA polymerase II | chromatin; nucleoplasm | DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding | Homo sapiens | Chromosomal rearrangement DNA-binding Nucleus Phosphoprotein Proto-oncogene Reference proteome Transcription Transcription regulation | MCPPQAQAEV | MCPPQAQAEVGPTMTEKAEMVCAPSPAPAPPPKPASPGPPQVEEVGHRGGSSPPRLPPGVPVISLGHSRPPGVAMPTTELGTLRPPLLQLSTLGTAPPTLALHYHPHPFLNSVYIGPAGPFSIFPSSRLKRRPSHCELDLAEGHQPQKVARRVFTNSRERWRQQNVNGAFAELRKLLPTHPPDRKLSKNEVLRLAMKYIGFLVRLLRDQAAALAAGPTPPGPRKRPVHRVPDDGARRGSGRRAEAAARSQPAPPADPDGSPGGAARPIKMEQTALSPEVR | B cell differentiation blood vessel maturation definitive hemopoiesis positive regulation of DNA-templated transcription regulation of DNA-templated transcription regulation of transcription by RNA polymerase II chromatin; nucleoplasm DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific pro... |
adult locomotory behavior axon guidance chromosome condensation chromosome segregation learning or memory locomotion mitotic cell cycle mitotic metaphase chromosome alignment nervous system development olfactory learning oogenesis positive regulation of canonical Wnt signaling pathway positive regulation of insulin rec... | cytoplasm; cytosol; nucleus; polytene chromosome; protein phosphatase type 1 complex | metal ion binding myosin phosphatase activity protein serine/threonine phosphatase activity | Drosophila melanogaster | Cytoplasm Hydrolase Manganese Metal-binding Protein phosphatase Reference proteome | MGDVMNIDSI | MGDVMNIDSIISRLLEVRGARPGKNVQLSEGEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYSENFFLLRGNHECASINRIYGFYDECKRRYSIKLWKTFTDCFNCLPVAAIVDEKIFCCHGGLSPDLTSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDTMGWGENDRGVSFTFGAEVVAKFLQKHEFDLICRAHQVVEDGYEFFAKRMLVTLFSAPNYCGEFDNAGAMMSVDDTLMCSFQILKPADKRKK | adult locomotory behavior axon guidance chromosome condensation chromosome segregation learning or memory locomotion mitotic cell cycle mitotic metaphase chromosome alignment nervous system development olfactory learning oogenesis positive regulation of canonical Wnt signaling pathway positive regulation of insulin rec... |
biotin biosynthetic process | cytoplasm | adenosylmethionine-8-amino-7-oxononanoate transaminase activity protein homodimerization activity pyridoxal phosphate binding | Escherichia coli | 3D-structure Aminotransferase Biotin biosynthesis Cytoplasm Pyridoxal phosphate Reference proteome S-adenosyl-L-methionine Transferase | MTTDDLAFDQ | MTTDDLAFDQRHIWHPYTSMTSPLPVYPVVSAEGCELILSDGRRLVDGMSSWWAAIHGYNHPQLNAAMKSQIDAMSHVMFGGITHAPAIELCRKLVAMTPQPLECVFLADSGSVAVEVAMKMALQYWQAKGEARQRFLTFRNGYHGDTFGAMSVCDPDNSMHSLWKGYLPENLFAPAPQSRMDGEWDERDMVGFARLMAAHRHEIAAVIIEPIVQGAGGMRMYHPEWLKRIRKICDREGILLIADEIATGFGRTGKLFACEHAEIAPDILCLGKALTGGTMTLSATLTTREVAETISNGEAGCFMHGPTFMGNPLACAAA... | biotin biosynthetic process cytoplasm adenosylmethionine-8-amino-7-oxononanoate transaminase activity protein homodimerization activity pyridoxal phosphate binding Escherichia coli 3D-structure Aminotransferase Biotin biosynthesis Cytoplasm Pyridoxal phosphate Reference proteome S-adenosyl-L-methionine Transferase MTTD... |
biotin biosynthetic process | cytosol | ATP binding dethiobiotin synthase activity magnesium ion binding protein homodimerization activity | Escherichia coli | 3D-structure ATP-binding Biotin biosynthesis Cytoplasm Direct protein sequencing Ligase Magnesium Metal-binding Nucleotide-binding Reference proteome | MSKRYFVTGT | MSKRYFVTGTDTEVGKTVASCALLQAAKAAGYRTAGYKPVASGSEKTPEGLRNSDALALQRNSSLQLDYATVNPYTFAEPTSPHIISAQEGRPIESLVMSAGLRALEQQADWVLVEGAGGWFTPLSDTFTFADWVTQEQLPVILVVGVKLGCINHAMLTAQVIQHAGLTLAGWVANDVTPPGKRHAEYMTTLTRMIPAPLLGEIPWLAENPENAATGKYINLALL | biotin biosynthetic process cytosol ATP binding dethiobiotin synthase activity magnesium ion binding protein homodimerization activity Escherichia coli 3D-structure ATP-binding Biotin biosynthesis Cytoplasm Direct protein sequencing Ligase Magnesium Metal-binding Nucleotide-binding Reference proteome MSKRYFVTGT MSKRYFV... |
biotin biosynthetic process | cytoplasm | carboxylic ester hydrolase activity pimelyl- methyl ester esterase activity | Escherichia coli | 3D-structure Biotin biosynthesis Cytoplasm Hydrolase Reference proteome Serine esterase | MNNIWWQTKG | MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHLVDLPGFGRSRGFGALSLADMAEAVLQQAPDKAIWLGWSLGGLVASQIALTHPERVQALVTVASSPCFSARDEWPGIKPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARALKKTVLALPMPEVDVLNGGLEILKTVDLRQPLQNVSMPFLRLYGYLDGLVPRKVVPMLDKLWPHSESYIFAKAAHAPFISHPAEFCHLLVALKQRV | biotin biosynthetic process cytoplasm carboxylic ester hydrolase activity pimelyl- methyl ester esterase activity Escherichia coli 3D-structure Biotin biosynthesis Cytoplasm Hydrolase Reference proteome Serine esterase MNNIWWQTKG MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHLVDLPGFGRSRGFGALSLADMAEAVLQQAPDKAIWLGWSLGGLVASQ... |
monounsaturated fatty acid biosynthetic process response to fatty acid unsaturated fatty acid biosynthetic process | endoplasmic reticulum; endoplasmic reticulum membrane; membrane; nucleolus | iron ion binding oxidoreductase activity palmitoyl-CoA 9-desaturase activity stearoyl-CoA 9-desaturase activity | Mus musculus | Endoplasmic reticulum Fatty acid biosynthesis Fatty acid metabolism Iron Lipid biosynthesis Lipid metabolism Membrane Metal-binding Microsome Oxidoreductase Reference proteome Transmembrane Transmembrane helix | MPAHILQEIS | MPAHILQEISGAYSATTTITAPPSGGQQNGGEKFEKSSHHWGADVRPELKDDLYDPTYQDDEGPPPKLEYVWRNIILMALLHLGALYGITLVPSCKLYTCLFAYLYYVISALGITAGAHRLWSHRTYKARLPLRLFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGGKLDMSDLKAEKLVMFQRRYYKPGLLLMCFVLPTLVPWYCWGETFVNSLCVSTFLRYAVVLNATWLVNSAAHLYGYRPYDKNISSRENILVSMGAVGEGFHNYHHAFPYDYSASEYRWHINFTT... | monounsaturated fatty acid biosynthetic process response to fatty acid unsaturated fatty acid biosynthetic process endoplasmic reticulum; endoplasmic reticulum membrane; membrane; nucleolus iron ion binding oxidoreductase activity palmitoyl-CoA 9-desaturase activity stearoyl-CoA 9-desaturase activity Mus musculus Endop... |
cellular response to hydrogen peroxide hydrogen peroxide catabolic process response to oxidative stress | cytosol | catalase activity heme binding identical protein binding metal ion binding oxidoreductase activity peroxidase activity | Escherichia coli | 3D-structure Direct protein sequencing Heme Hydrogen peroxide Iron Metal-binding Oxidoreductase Peroxidase Reference proteome | MSTSDDIHNT | MSTSDDIHNTTATGKCPFHQGGHDQSAGAGTTTRDWWPNQLRVDLLNQHSNRSNPLGEDFDYRKEFSKLDYYGLKKDLKALLTESQPWWPADWGSYAGLFIRMAWHGAGTYRSIDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWADLFILAGNVALENSGFRTFGFGAGREDVWEPDLDVNWGDEKAWLTHRHPEALAKAPLGATEMGLIYVNPEGPDHSGEPLSAAAAIRATFGNMGMNDEETVALIAGGHTLGKTHGAGPTSNVGPDPEAAPIEEQGLGWASTYGSGVGADAITSGLEVVWTQ... | cellular response to hydrogen peroxide hydrogen peroxide catabolic process response to oxidative stress cytosol catalase activity heme binding identical protein binding metal ion binding oxidoreductase activity peroxidase activity Escherichia coli 3D-structure Direct protein sequencing Heme Hydrogen peroxide Iron Metal... |
intracellular iron ion homeostasis iron ion transport regulation of DNA-templated transcription response to iron ion starvation siderophore-dependent iron import into cell signal transduction involved in regulation of gene expression | cell outer membrane; membrane; transmembrane transporter complex | siderophore-iron transmembrane transporter activity signaling receptor activity | Escherichia coli | 3D-structure Cell outer membrane Direct protein sequencing Ion transport Iron Iron transport Membrane Receptor Reference proteome Signal TonB box Transmembrane Transmembrane beta strand Transport | MTPLRVFRKT | MTPLRVFRKTTPLVNTIRLSLLPLAGLSFSAFAAQVNIAPGSLDKALNQYAAHSGFTLSVDASLTRGKQSNGLHGDYDVESGLQQLLDGSGLQVKPLGNNSWTLEPAPAPKEDALTVVGDWLGDARENDVFEHAGARDVIRREDFAKTGATTMREVLNRIPGVSAPENNGTGSHDLAMNFGIRGLNPRLASRSTVLMDGIPVPFAPYGQPQLSLAPVSLGNMDAIDVVRGGGAVRYGPQSVGGVVNFVTRAIPQDFGIEAGVEGQLSPTSSQNNPKETHNLMVGGTADNGFGTALLYSGTRGSDWREHSATRIDDLMLKS... | intracellular iron ion homeostasis iron ion transport regulation of DNA-templated transcription response to iron ion starvation siderophore-dependent iron import into cell signal transduction involved in regulation of gene expression cell outer membrane; membrane; transmembrane transporter complex siderophore-iron tran... |
enterobactin catabolic process siderophore-dependent iron import into cell | cytoplasm | enterochelin esterase activity iron ion binding | Escherichia coli | Cytoplasm Direct protein sequencing Hydrolase Reference proteome | MTALKVGSES | MTALKVGSESWWQSKHGPEWQRLNDEMFEVTFWWRDPQGSEEYSTIKRVWVYITGVTDHHQNSQPQSMQRIAGTNVWQWTTQLNANWRGSYCFIPTERDDIFSVPSPDRLELREGWRKLLPQAIADPLNLQSWKGGRGHAVSALEMPQAPLQPGWDCPQAPEIPAKEIIWKSERLKKSRRVWIFTTGDATAEERPLAVLLDGEFWAQSMPVWPVLTSLTHRQQLPPAVYVLIDAIDTTHRAHELPCNADFWLAVQQELLPLVKAIAPFSDRADRTVVAGQSFGGLSALYAGLHWPERFGCVLSQSGSYWWPHRGGQQEGV... | enterobactin catabolic process siderophore-dependent iron import into cell cytoplasm enterochelin esterase activity iron ion binding Escherichia coli Cytoplasm Direct protein sequencing Hydrolase Reference proteome MTALKVGSES MTALKVGSESWWQSKHGPEWQRLNDEMFEVTFWWRDPQGSEEYSTIKRVWVYITGVTDHHQNSQPQSMQRIAGTNVWQWTTQLNANWRGSYCFI... |
base-excision repair base-excision repair, AP site formation via deaminated base removal depyrimidination isotype switching negative regulation of apoptotic process somatic hypermutation of immunoglobulin genes | mitochondrion; nucleoplasm; nucleus | damaged DNA binding ribosomal small subunit binding uracil DNA N-glycosylase activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Direct protein sequencing Disease variant DNA damage DNA repair Host-virus interaction Hydrolase Mitochondrion Nucleus Phosphoprotein Reference proteome | MIGQKTLYSF | MIGQKTLYSFFSPSPARKRHAPSPEPAVQGTGVAGVPEESGDAAAIPAKKAPAGQEEPGTPPSSPLSAEQLDRIQRNKAAALLRLAARNVPVGFGESWKKHLSGEFGKPYFIKLMGFVAEERKHYTVYPPPHQVFTWTQMCDIKDVKVVILGQDPYHGPNQAHGLCFSVQRPVPPPPSLENIYKELSTDIEDFVHPGHGDLSGWAKQGVLLLNAVLTVRAHQANSHKERGWEQFTDAVVSWLNQNSNGLVFLLWGSYAQKKGSAIDRKRHHVLQTAHPSPLSVYRGFFGCRHFSKTNELLQKSGKKPIDWKEL | base-excision repair base-excision repair, AP site formation via deaminated base removal depyrimidination isotype switching negative regulation of apoptotic process somatic hypermutation of immunoglobulin genes mitochondrion; nucleoplasm; nucleus damaged DNA binding ribosomal small subunit binding uracil DNA N-glycosyl... |
anatomical structure development cell differentiation negative regulation of transcription by RNA polymerase II positive regulation of retinoic acid receptor signaling pathway | chromatin; nucleoplasm; PML body | DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific histone deacetylase binding nuclear receptor activity nuclear steroid receptor activity protein homodimerization activity RNA polymerase II cis-regulatory region seq... | Homo sapiens | Activator Alternative splicing DNA-binding Isopeptide bond Metal-binding Nucleus Phosphoprotein Receptor Reference proteome Repressor Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | MATIEEIAHQ | MATIEEIAHQIIEQQMGEIVTEQQTGQKIQIVTALDHNTQGKQFILTNHDGSTPSKVILARQDSTPGKVFLTTPDAAGVNQLFFTTPDLSAQHLQLLTDNSPDQGPNKVFDLCVVCGDKASGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQRCIAFGMKQDSVQCERKPIEVSREKSSNCAASTEKIYIRKDLRSPLTATPTFVTDSESTRSTGLLDSGMFMNIHPSGVKTESAVLMTSDKAESCQGDLSTLANVVTSLANLGKTKDLSQNSNEMSMIESLSNDDTSLCEFQEMQTNGDV... | anatomical structure development cell differentiation negative regulation of transcription by RNA polymerase II positive regulation of retinoic acid receptor signaling pathway chromatin; nucleoplasm; PML body DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription rep... |
cellular respiration generation of precursor metabolites and energy mitochondrial electron transport, cytochrome c to oxygen | cytosol; membrane; mitochondrial inner membrane; mitochondrial membrane; mitochondrial respiratory chain complex IV; mitochondrion; nucleoplasm | cytochrome-c oxidase activity | Homo sapiens | 3D-structure Acetylation Direct protein sequencing Disease variant Membrane Mitochondrion Mitochondrion inner membrane Phosphoprotein Primary mitochondrial disease Reference proteome Transit peptide Transmembrane Transmembrane helix | MLATRVFSLV | MLATRVFSLVGKRAISTSVCVRAHESVVKSEDFSLPAYMDRRDHPLPEVAHVKHLSASQKALKEKEKASWSSLSMDEKVELYRIKFKESFAEMNRGSNEWKTVVGGAMFFIGFTALVIMWQKHYVYGPLPQSFDKEWVAKQTKRMLDMKVNPIQGLASKWDYEKNEWKK | cellular respiration generation of precursor metabolites and energy mitochondrial electron transport, cytochrome c to oxygen cytosol; membrane; mitochondrial inner membrane; mitochondrial membrane; mitochondrial respiratory chain complex IV; mitochondrion; nucleoplasm cytochrome-c oxidase activity Homo sapiens 3D-struc... |
adenylate cyclase-activating G protein-coupled receptor signaling pathway bone mineralization chondrocyte differentiation endochondral ossification endoderm development lung alveolus development lung epithelial cell differentiation mammary gland bud elongation negative regulation of chondrocyte development negative reg... | cytoplasm; extracellular region; nucleus | hormone activity peptide hormone receptor binding | Rattus norvegicus | Calcium Cleavage on pair of basic residues Cytoplasm Hormone Nucleus Reference proteome Secreted Signal | MLRRLVQQWS | MLRRLVQQWSVLVFLLSYSVPSRGRSVEGLGRRLKRAVSEHQLLHDKGKSIQDLRRRFFLHHLIAEIHTAEIRATSEVSPNSKPAPNTKNHPVRFGSDDEGRYLTQETNKVETYKEQPLKTPGKKKKGKPGKRREQEKKKRRTRSAWPGTTGSGLLEDPQPHTSPTSTSLEPSSRTH | adenylate cyclase-activating G protein-coupled receptor signaling pathway bone mineralization chondrocyte differentiation endochondral ossification endoderm development lung alveolus development lung epithelial cell differentiation mammary gland bud elongation negative regulation of chondrocyte development negative reg... |
succinate metabolic process succinyl-CoA metabolic process tricarboxylic acid cycle | mitochondrion; protein-containing complex; succinate-CoA ligase complex (ADP-forming); succinate-CoA ligase complex (GDP-forming) | GDP binding protein-containing complex binding succinate-CoA ligase (ADP-forming) activity succinate-CoA ligase (GDP-forming) activity | Rattus norvegicus | Acetylation Ligase Mitochondrion Nucleotide-binding Reference proteome Transit peptide Tricarboxylic acid cycle | MTAAVVAAAA | MTAAVVAAAATATMVSGSSGLAAARLLSRTFLLQQNGIRHGSYTASRKNIYIDKNTKVICQGFTGKQGTFHSQQALEYGTKLVGGTTPGKGGKKHLGLPVFNTVKEAKEKTGATASVIYVPPPFAAAAINEAIDAEIPLVVCITEGIPQQDMVRVKHKLTRQGKTRLIGPNCPGIINPGECKIGIMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVGLGQSLCIGIGGDPFNGTNFIDCLDVFLKDPATEGIVLIGEIGGHAEENAAEFLKEHNSGPKAKPVVSFIAGITAPPGRRMGHAGAIIAGGKGGAKEKISALQS... | succinate metabolic process succinyl-CoA metabolic process tricarboxylic acid cycle mitochondrion; protein-containing complex; succinate-CoA ligase complex (ADP-forming); succinate-CoA ligase complex (GDP-forming) GDP binding protein-containing complex binding succinate-CoA ligase (ADP-forming) activity succinate-CoA l... |
anterior/posterior pattern specification cell differentiation nervous system development regulation of neurogenesis regulation of transcription by RNA polymerase II | nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific protein heterodimerization activity protein homodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding | Drosophila melanogaster | Developmental protein Differentiation DNA-binding Neurogenesis Nucleus Reference proteome Repressor Transcription Transcription regulation | MAPQSNNSTT | MAPQSNNSTTFVSKTQHYLKVKKPLLERQRRARMNKCLDTLKTLVAEFQGDDAILRMDKAEMLEAALVFMRKQVVKQQAPVSPLPMDSFKNGYMNAVSEISRVMACTPAMSVDVGKTVMTHLGVEFQRMLQADQVQTSVTTSTPRPLSPASSGYHSDNEDSQSAASPKPVEETMWRPW | anterior/posterior pattern specification cell differentiation nervous system development regulation of neurogenesis regulation of transcription by RNA polymerase II nucleus DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific prot... |
anterior/posterior pattern specification cell differentiation negative regulation of transcription by RNA polymerase II nervous system development regulation of neurogenesis regulation of transcription by RNA polymerase II | nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor binding DNA-binding transcription repressor activity, RNA polymerase II-specific protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding sequen... | Drosophila melanogaster | Developmental protein Differentiation DNA-binding Neurogenesis Nucleus Reference proteome Repressor Transcription Transcription regulation | MATKYEMSKT | MATKYEMSKTYQYRKVMKPLLERKRRARINKCLDELKDLMAECVAQTGDAKFEKADILEVTVQHLRKLKESKKHVPANPEQSFRAGYIRAANEVSRALASLPRVDVAFGTTLMTHLGMRLNQLEQPMEQPQAVNTPLSIVCGSSSSSSTYSSASSCSSISPVSSGYASDNESLLQISSPGQVWRPW | anterior/posterior pattern specification cell differentiation negative regulation of transcription by RNA polymerase II nervous system development regulation of neurogenesis regulation of transcription by RNA polymerase II nucleus DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcr... |
anterior/posterior pattern specification compound eye development dendrite morphogenesis mesoderm development negative regulation of gene expression regulation of neurogenesis regulation of transcription by RNA polymerase II sensory organ precursor cell fate determination | nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific protein heterodimerization activity protein homodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding | Drosophila melanogaster | Developmental protein Differentiation DNA-binding Neurogenesis Nucleus Reference proteome Repressor Transcription Transcription regulation | MEYTTKTQIY | MEYTTKTQIYQKVKKPMLERQRRARMNKCLDNLKTLVAELRGDDGILRMDKAEMLESAVIFMRQQKTPKKVAQEEQSLPLDSFKNGYMNAVNEVSRVMASTPGMSVDLGKSVMTHLGRVYKNLQQFHEAQSAADFIQNSMDCSSMDKAPLSPASSGYHSDCDSPAPSPQPMQQPLWRPW | anterior/posterior pattern specification compound eye development dendrite morphogenesis mesoderm development negative regulation of gene expression regulation of neurogenesis regulation of transcription by RNA polymerase II sensory organ precursor cell fate determination nucleus DNA-binding transcription factor activi... |
DNA topological change double-strand break repair via homologous recombination mitotic sister chromatid cohesion reciprocal meiotic recombination regulation of DNA recombination telomere maintenance via telomerase | nucleus; RecQ family helicase-topoisomerase III complex | DNA binding DNA topoisomerase activity DNA topoisomerase type I (single strand cut, ATP-independent) activity | Saccharomyces cerevisiae | Direct protein sequencing DNA-binding Isomerase Reference proteome Topoisomerase | MKVLCVAEKN | MKVLCVAEKNSIAKAVSQILGGGRSTSRDSGYMYVKNYDFMFSGFPFARNGANCEVTMTSVAGHLTGIDFSHDSHGWGKCAIQELFDAPLNEIMNNNQKKIASNIKREARNADYLMIWTDCDREGEYIGWEIWQEAKRGNRLIQNDQVYRAVFSHLERQHILNAARNPSRLDMKSVHAVGTRIEIDLRAGVTFTRLLTETLRNKLRNQATMTKDGAKHRGGNKNDSQVVSYGTCQFPTLGFVVDRFERIRNFVPEEFWYIQLVVENKDNGGTTTFQWDRGHLFDRLSVLTFYETCIETAGNVAQVVDLKSKPTTKYRPLP... | DNA topological change double-strand break repair via homologous recombination mitotic sister chromatid cohesion reciprocal meiotic recombination regulation of DNA recombination telomere maintenance via telomerase nucleus; RecQ family helicase-topoisomerase III complex DNA binding DNA topoisomerase activity DNA topoiso... |
cellular ketone metabolic process epoxygenase P450 pathway response to organic cyclic compound response to stilbenoid response to xenobiotic stimulus steroid metabolic process xenobiotic catabolic process xenobiotic metabolic process | cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle | anandamide 11,12 epoxidase activity anandamide 14,15 epoxidase activity anandamide 8,9 epoxidase activity arachidonic acid epoxygenase activity aromatase activity estrogen 2-hydroxylase activity heme binding iron ion binding monooxygenase activity oxidoreductase activity, acting on paired donors, with incorporation or ... | Rattus norvegicus | Endoplasmic reticulum Heme Iron Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Reference proteome | MDTSVLLLLA | MDTSVLLLLAVLLSFLLFLVRGHAKVHGHLPPGPRPLPLLGNLLQMDRGGFRKSFIQLQEKHGDVFTVYFGPRPVVMLCGTQTIREALVDHAEAFSGRGIIAVLQPIMQEYGVSFVNEERWKILRRLFVATMRDFGIGKQSVEDQIKEEAKCLVEELKNHQGVSLDPTFLFQCVTGNIICSIVFGERFDYRDRQFLRLLDLLYRTFSLISSFSSQMFEVYSDFLKYFPGVHREIYKNLKEVLDYIDHSVENHRATLDPNAPRDFIDTFLLHMEKEKLNHYTEFHHWNLMISVLFLFLAGTESTSNTLCYGFLLMLKYPHV... | cellular ketone metabolic process epoxygenase P450 pathway response to organic cyclic compound response to stilbenoid response to xenobiotic stimulus steroid metabolic process xenobiotic catabolic process xenobiotic metabolic process cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle an... |
auxin polar transport flavonoid biosynthetic process regulation of anthocyanin biosynthetic process response to auxin response to gravity response to jasmonic acid response to oxidative stress response to UV-B response to wounding | endoplasmic reticulum; nucleus; plant-type vacuole membrane | chalcone synthase activity naringenin-chalcone synthase activity | Arabidopsis thaliana | 3D-structure Acetylation Acyltransferase Alternative initiation Flavonoid biosynthesis Reference proteome Transferase | MVMAGASSLD | MVMAGASSLDEIRQAQRADGPAGILAIGTANPENHVLQAEYPDYYFRITNSEHMTDLKEKFKRMCDKSTIRKRHMHLTEEFLKENPHMCAYMAPSLDTRQDIVVVEVPKLGKEAAVKAIKEWGQPKSKITHVVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRIAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSDPDTSVGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIVKSLDEAFKPLGISDWNSLFWIAHPGGPAILDQVE... | auxin polar transport flavonoid biosynthetic process regulation of anthocyanin biosynthetic process response to auxin response to gravity response to jasmonic acid response to oxidative stress response to UV-B response to wounding endoplasmic reticulum; nucleus; plant-type vacuole membrane chalcone synthase activity na... |
killing of cells of another organism | extracellular region; host cell plasma membrane; membrane | cholesterol binding identical protein binding toxin activity | Listeria monocytogenes serovar 1/2a | 3D-structure Cytolysis Hemolysis Host cell membrane Host membrane Lipid-binding Membrane Phosphoprotein Reference proteome Secreted Signal Toxin Transmembrane Transmembrane beta strand Ubl conjugation Virulence | MKKIMLVFIT | MKKIMLVFITLILVSLPIAQQTEAKDASAFNKENSISSMAPPASPPASPKTPIEKKHADEIDKYIQGLDYNKNNVLVYHGDAVTNVPPRKGYKDGNEYIVVEKKKKSINQNNADIQVVNAISSLTYPGALVKANSELVENQPDVLPVKRDSLTLSIDLPGMTNQDNKIVVKNATKSNVNNAVNTLVERWNEKYAQAYPNVSAKIDYDDEMAYSESQLIAKFGTAFKAVNNSLNVNFGAISEGKMQEEVISFKQIYYNVNVNEPTRPSRFFGKAVTKEQLQALGVNAENPPAYISSVAYGRQVYLKLSTNSHSTKVKAAFD... | killing of cells of another organism extracellular region; host cell plasma membrane; membrane cholesterol binding identical protein binding toxin activity Listeria monocytogenes serovar 1/2a 3D-structure Cytolysis Hemolysis Host cell membrane Host membrane Lipid-binding Membrane Phosphoprotein Reference proteome Secre... |
peptide pheromone maturation protein processing | fungal-type vacuole; membrane; trans-Golgi network | metal ion binding serine-type endopeptidase activity | Saccharomyces cerevisiae | 3D-structure Calcium Cleavage on pair of basic residues Disulfide bond Glycoprotein Golgi apparatus Hydrolase Membrane Metal-binding Protease Reference proteome Serine protease Signal Transmembrane Transmembrane helix Zymogen | MKVRKYITLC | MKVRKYITLCFWWAFSTSALVSSQQIPLKDHTSRQYFAVESNETLSRLEEMHPNWKYEHDVRGLPNHYVFSKELLKLGKRSSLEELQGDNNDHILSVHDLFPRNDLFKRLPVPAPPMDSSLLPVKEAEDKLSINDPLFERQWHLVNPSFPGSDINVLDLWYNNITGAGVVAAIVDDGLDYENEDLKDNFCAEGSWDFNDNTNLPKPRLSDDYHGTRCAGEIAAKKGNNFCGVGVGYNAKISGIRILSGDITTEDEAASLIYGLDVNDIYSCSWGPADDGRHLQGPSDLVKKALVKGVTEGRDSKGAIYVFASGNGGTRGD... | peptide pheromone maturation protein processing fungal-type vacuole; membrane; trans-Golgi network metal ion binding serine-type endopeptidase activity Saccharomyces cerevisiae 3D-structure Calcium Cleavage on pair of basic residues Disulfide bond Glycoprotein Golgi apparatus Hydrolase Membrane Metal-binding Protease ... |
cellular response to insulin stimulus cellular response to organic cyclic compound erythrocyte development heme A biosynthetic process heme B biosynthetic process heme biosynthetic process heme O biosynthetic process hemoglobin biosynthetic process protoporphyrinogen IX biosynthetic process response to bile acid respon... | mitochondrial inner membrane; mitochondrial matrix; mitochondrion | 5-aminolevulinate synthase activity identical protein binding pyridoxal phosphate binding | Rattus norvegicus | Acyltransferase Heme biosynthesis Hydroxylation Membrane Mitochondrion Mitochondrion inner membrane Pyridoxal phosphate Reference proteome Transferase Transit peptide Ubl conjugation | METVVRRCPF | METVVRRCPFLSRVPQAFLQKAGKSLLFYAQNCPKMMEVGAKPAPRTVSTSAAQCQQVKETPPANEKEKTAKAAVQQAPDESQMAQTPDGTQLPPGHPSPSTSQSSGSKCPFLAAQLSQTGSSVFRKASLELQEDVQEMHAVRKEVAQSPVLPSLVNAKRDGEGPSPLLKNFQDIMRKQRPERVSHLLQDNLPKSVSTFQYDHFFEKKIDEKKNDHTYRVFKTVNRRAQIFPMADDYTDSLITKKQVSVWCSNDYLGMSRHPRVCGAVIETVKQHGAGAGGTRNISGTSKFHVELEQELADLHGKDAALLFSSCFVANDS... | cellular response to insulin stimulus cellular response to organic cyclic compound erythrocyte development heme A biosynthetic process heme B biosynthetic process heme biosynthetic process heme O biosynthetic process hemoglobin biosynthetic process protoporphyrinogen IX biosynthetic process response to bile acid respon... |
erythrocyte development heme A biosynthetic process heme B biosynthetic process heme biosynthetic process heme O biosynthetic process hemoglobin biosynthetic process protoporphyrinogen IX biosynthetic process response to bile acid | cytosol; mitochondrial inner membrane; mitochondrial matrix; mitochondrion; nucleoplasm | 5-aminolevulinate synthase activity identical protein binding pyridoxal phosphate binding | Homo sapiens | Acyltransferase Alternative splicing Heme biosynthesis Hydroxylation Membrane Mitochondrion Mitochondrion inner membrane Pyridoxal phosphate Reference proteome Transferase Transit peptide Ubl conjugation | MESVVRRCPF | MESVVRRCPFLSRVPQAFLQKAGKSLLFYAQNCPKMMEVGAKPAPRALSTAAVHYQQIKETPPASEKDKTAKAKVQQTPDGSQQSPDGTQLPSGHPLPATSQGTASKCPFLAAQMNQRGSSVFCKASLELQEDVQEMNAVRKEVAETSAGPSVVSVKTDGGDPSGLLKNFQDIMQKQRPERVSHLLQDNLPKSVSTFQYDRFFEKKIDEKKNDHTYRVFKTVNRRAHIFPMADDYSDSLITKKQVSVWCSNDYLGMSRHPRVCGAVMDTLKQHGAGAGGTRNISGTSKFHVDLERELADLHGKDAALLFSSCFVANDSTL... | erythrocyte development heme A biosynthetic process heme B biosynthetic process heme biosynthetic process heme O biosynthetic process hemoglobin biosynthetic process protoporphyrinogen IX biosynthetic process response to bile acid cytosol; mitochondrial inner membrane; mitochondrial matrix; mitochondrion; nucleoplasm 5... |
regulation of DNA-templated transcription | host cell cytoplasm; host cell nucleus | metal ion binding molecular adaptor activity RNA binding | Saimiriine herpesvirus 2 | 3D-structure Activator Early protein Host cytoplasm Host nucleus Metal-binding Reference proteome RNA-binding Transcription Transcription regulation Zinc Zinc-finger | MEDIIEGGIS | MEDIIEGGISSDDDFDSSDSSSDEEESDTSPQIMKSDVTMASPPSTPEPSPDVSASTSNLKRERQRSPITWEHQSPLSRVYRSPSPMRFGKRPRISSNSTSRSCKTSWADRVREAAAQRRPSRPFRKPYSHPRNGPLRNGPPRAPPLLKLFDISILPKSGEPKLFLPVPSLPCQEAEKTNDKYVLAMAQRAMHDVPISSKQLTANLLPVKFKPLLSIVRYTPNYYYWVSMRKETIASANLCTVAAFLDESLCWGQQYLKNDFIFSENGKDIILDTSSALLSQLVHKIKMLPFCHCLMQTTPQDHIVKQVCYLIASNNRIL... | regulation of DNA-templated transcription host cell cytoplasm; host cell nucleus metal ion binding molecular adaptor activity RNA binding Saimiriine herpesvirus 2 3D-structure Activator Early protein Host cytoplasm Host nucleus Metal-binding Reference proteome RNA-binding Transcription Transcription regulation Zinc Z... |
regulation of vasoconstriction vasoconstriction | extracellular region | toxin activity | Atractaspis engaddensis | 3D-structure Cardiotoxin Direct protein sequencing Disulfide bond G-protein coupled receptor impairing toxin Repeat Secreted Signal Toxin Vasoactive Vasoconstrictor | MALLPRLAAG | MALLPRLAAGGLLLLLALAALEGKPAPSALSQLLEKRSEDQAAAGRIIDGGDTKQAARDPSPQRNVEPLCSCKDMSDKECLNFCHQDVIWRDTKQAARDPSPQRNVEPLCTCNDMTDEECLNFCHQDVIWRDTKQAARDPSPQRNVEPLCSCKDMTDKECLYFCHQDVIWRDTKQAARDPSPQRNVEPLCTCNDMTDEECLNFCHQDVIWRDTKQAARDPSPQRNVEPLCTCNDMTDEECLNFCHQDVIWRDTKQAARDPSPQRNVEPLCTCKDMTDKECLYFCHQGIIWRDTKQAARDPSPQRNVEPLCSCKDMSDKEC... | regulation of vasoconstriction vasoconstriction extracellular region toxin activity Atractaspis engaddensis 3D-structure Cardiotoxin Direct protein sequencing Disulfide bond G-protein coupled receptor impairing toxin Repeat Secreted Signal Toxin Vasoactive Vasoconstrictor MALLPRLAAG MALLPRLAAGGLLLLLALAALEGKPAPSALSQLLE... |
anatomical structure development negative regulation of angiogenesis negative regulation of endothelial cell proliferation positive regulation of endothelial cell migration regulation of cell morphogenesis | basement membrane; cell surface; extracellular space; nuclear matrix; platelet alpha granule membrane | calcium ion binding collagen binding extracellular matrix binding | Bos taurus | Basement membrane Calcium Copper Direct protein sequencing Disulfide bond Extracellular matrix Glycoprotein Metal-binding Reference proteome Secreted Signal | MRAWIFFLLC | MRAWIFFLLCLAGRALAAPQQEALPDETEVVEETVAEVAEVPVGANPVQVEVGEFDDGAEETEEEVVAENPCQNHHCKHGKVCELDENNTPMCVCQDPTSCPAPIGEFEKVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLDSELTEFPLRMRDWLKNVLVTLYERDEDNNLLTEKQKLRVKKIHENEKRLEAGDHPVELLARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFETCDLDNDKYIALDEWAGCFGIKEKDIDKDLVI | anatomical structure development negative regulation of angiogenesis negative regulation of endothelial cell proliferation positive regulation of endothelial cell migration regulation of cell morphogenesis basement membrane; cell surface; extracellular space; nuclear matrix; platelet alpha granule membrane calcium ion ... |
epithelial cell differentiation negative regulation of interleukin-8 production Notch signaling pathway regulation of transcription by RNA polymerase II | apical plasma membrane; cell surface; chromaffin granule membrane; cytoplasm; cytosol; membrane; nuclear membrane; nucleus; perinuclear region of cytoplasm; zymogen granule membrane | calcium ion binding calcium-dependent phospholipid binding calcium-dependent protein binding carbohydrate binding chondroitin sulfate binding heparin binding identical protein binding NF-kappaB binding | Bos taurus | 3D-structure Acetylation Annexin Calcium Calcium/phospholipid-binding Cytoplasmic vesicle Direct protein sequencing Membrane Phosphoprotein Reference proteome Repeat | MAAKGGTVKA | MAAKGGTVKAASGFNAAEDAQTLRKAMKGLGTDEDAIINVLAYRSTAQRQEIRTAYKTTIGRDLMDDLKSELSGNFEQVILGMMTPTVLYDVQELRKAMKGAGTDEGCLIEILASRTPEEIRRINQTYQLQYGRSLEDDIRSDTSFMFQRVLVSLSAGGRDESNYLDDALMRQDAQDLYEAGEKKWGTDEVKFLTVLCSRNRNHLLHVFDEYKRIAQKDIEQSIKSETSGSFEDALLAIVKCMRNKSAYFAERLYKSMKGLGTDDDTLIRVMVSRAEIDMLDIRANFKRLYGKSLYSFIKGDTSGDYRKVLLILCGGDD | epithelial cell differentiation negative regulation of interleukin-8 production Notch signaling pathway regulation of transcription by RNA polymerase II apical plasma membrane; cell surface; chromaffin granule membrane; cytoplasm; cytosol; membrane; nuclear membrane; nucleus; perinuclear region of cytoplasm; zymogen gr... |
2-oxoglutarate metabolic process aspartate biosynthetic process aspartate catabolic process aspartate metabolic process cellular response to insulin stimulus cellular response to mechanical stimulus dicarboxylic acid metabolic process fatty acid homeostasis gluconeogenesis glutamate catabolic process to 2-oxoglutarate ... | axon terminus; cytoplasm; cytosol | carboxylic acid binding L-aspartate:2-oxoglutarate aminotransferase activity L-cysteine transaminase activity phosphatidylserine decarboxylase activity pyridoxal phosphate binding | Rattus norvegicus | Amino-acid biosynthesis Aminotransferase Cytoplasm Direct protein sequencing Phosphoprotein Pyridoxal phosphate Reference proteome Transferase | MAPPSFFAQV | MAPPSFFAQVPQAPPVLVFKLIADFRDDPDPRKVNLGVGAYRTDDSQPWVLPVVRKVEQKIANDHSLNHEYLPILGLAEFRSCASQLVLGDNSPALRENRVGGVQSLGGTGALRIGADFLGRWYNGTDNKNTPVYVSSPTWENHNGVFSAAGFKDIRSYRYWDAEKRGLDLQGFLNDLENAPEFSIFVLHACAHNPTGTDPTEEEWKQIAAVMKRRFLFPFFDSAYQGFASGDLEKDAWAIRYFVSEGFELFCAQSFSKNFGLYNERVGNLTVVGKEHDSVLRVLSQMEKIVRITWSNPPAQGARIVATTLSNPELFKEW... | 2-oxoglutarate metabolic process aspartate biosynthetic process aspartate catabolic process aspartate metabolic process cellular response to insulin stimulus cellular response to mechanical stimulus dicarboxylic acid metabolic process fatty acid homeostasis gluconeogenesis glutamate catabolic process to 2-oxoglutarate ... |
blood coagulation, intrinsic pathway cell adhesion cell surface receptor signaling pathway megakaryocyte development platelet activation positive regulation of platelet activation release of sequestered calcium ion into cytosol | glycoprotein Ib-IX-V complex; plasma membrane | identical protein binding transmembrane signaling receptor activity | Homo sapiens | 3D-structure Alternative splicing Bernard Soulier syndrome Blood coagulation Cell adhesion Direct protein sequencing Disease variant Disulfide bond Glycoprotein Hemostasis Leucine-rich repeat Membrane Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix | MGSGPRGALS | MGSGPRGALSLLLLLLAPPSRPAAGCPAPCSCAGTLVDCGRRGLTWASLPTAFPVDTTELVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRDLRCVAPPALRGRLLPYLAEDELRAACAPGPLCWGALAAQLALLGLGLLHALLLVLLLCRLRRLRARARARAAARLSLTDPLVAERAGTDES | blood coagulation, intrinsic pathway cell adhesion cell surface receptor signaling pathway megakaryocyte development platelet activation positive regulation of platelet activation release of sequestered calcium ion into cytosol glycoprotein Ib-IX-V complex; plasma membrane identical protein binding transmembrane signal... |
actin filament polymerization hyperosmotic response response to acidic pH | actin cytoskeleton; cortical cytoskeleton; cytosol; phagocytic vesicle; plasma membrane | actin filament binding actin monomer binding fatty acid binding lipid binding protein-macromolecule adaptor activity | Dictyostelium discoideum | 3D-structure Actin-binding Cell membrane Cytoplasm Direct protein sequencing Disulfide bond Lipoprotein Membrane Myristate Phosphoprotein Reference proteome Repeat | MGNRAFKSHH | MGNRAFKSHHGHFLSAEGEAVKTHHGHHDHHTHFHVENHGGKVALKTHCGKYLSIGDHKQVYLSHHLHGDHSLFHLEHHGGKVSIKGHHHHYISADHHGHVSTKEHHDHDTTFEEIII | actin filament polymerization hyperosmotic response response to acidic pH actin cytoskeleton; cortical cytoskeleton; cytosol; phagocytic vesicle; plasma membrane actin filament binding actin monomer binding fatty acid binding lipid binding protein-macromolecule adaptor activity Dictyostelium discoideum 3D-structure Act... |
animal organ morphogenesis B cell proliferation bone resorption cell-cell signaling cytokine-mediated signaling pathway extrinsic apoptotic signaling pathway homeostasis of number of cells within a tissue humoral immune response negative regulation of apoptotic process negative regulation of extrinsic apoptotic signali... | collagen-containing extracellular matrix; extracellular region; extracellular space | cytokine activity growth factor activity interleukin-7 receptor binding | Homo sapiens | 3D-structure Alternative splicing Cytokine Disease variant Disulfide bond Glycoprotein Growth factor Reference proteome Secreted Signal | MFHVSFRYIF | MFHVSFRYIFGLPPLILVLLPVASSDCDIEGKDGKQYESVLMVSIDQLLDSMKEIGSNCLNNEFNFFKRHICDANKEGMFLFRAARKLRQFLKMNSTGDFDLHLLKVSEGTTILLNCTGQVKGRKPAALGEAQPTKSLEENKSLKEQKKLNDLCFLKRLLQEIKTCWNKILMGTKEH | animal organ morphogenesis B cell proliferation bone resorption cell-cell signaling cytokine-mediated signaling pathway extrinsic apoptotic signaling pathway homeostasis of number of cells within a tissue humoral immune response negative regulation of apoptotic process negative regulation of extrinsic apoptotic signali... |
adult locomotory behavior axonogenesis cyclic nucleotide catabolic process forebrain development oligodendrocyte differentiation regulation of mitochondrial membrane permeability response to lipopolysaccharide response to toxic substance | cell projection; cytoplasm; extracellular space; melanosome; membrane; microvillus; mitochondrial inner membrane; mitochondrial outer membrane; myelin sheath; myelin sheath abaxonal region; myelin sheath adaxonal region; perinuclear region of cytoplasm; pseudopodium | 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity cyclic nucleotide binding RNA binding | Rattus norvegicus | 3D-structure Direct protein sequencing Hydrolase Lipoprotein Membrane Methylation Phosphoprotein Prenylation Reference proteome RNA-binding | MSTSFARKSH | MSTSFARKSHTFLPKIFFRKMSSSGAKDKPELQFPFLQDEDTVATLHECKTLFILRGLPGSGKSTLARLIVEKYHNGTKMVSADAYKIIPGSRADFSEEYKRLDEDLAGYCRRDIRVLVLDDTNHERERLDQLFEMADQYQYQVVLVEPKTAWRLDCAQLKEKNQWQLSLDDLKKLKPGLEKDFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFISGDEPKEKLDLVSYFGKRPPGVLHCTTKFCDYGKATGAEEYAQQDVVRRSYGKAFKLSISALFVTPKTAGAQVVLNEQELQLWPSDLDKPSSSE... | adult locomotory behavior axonogenesis cyclic nucleotide catabolic process forebrain development oligodendrocyte differentiation regulation of mitochondrial membrane permeability response to lipopolysaccharide response to toxic substance cell projection; cytoplasm; extracellular space; melanosome; membrane; microvillus... |
adaptive immune response inflammatory response intracellular signal transduction long-term memory myeloid dendritic cell differentiation neuron-neuron synaptic transmission nucleocytoplasmic transport phosphorylation positive regulation of DNA-templated transcription positive regulation of protein export from nucleus p... | cytoplasm; GABA-ergic synapse; glutamatergic synapse; nucleoplasm; nucleus; postsynapse | ATP binding calcium-dependent protein serine/threonine kinase activity calmodulin binding calmodulin-dependent protein kinase activity protein serine kinase activity | Rattus norvegicus | Adaptive immunity Alternative promoter usage Alternative splicing ATP-binding Calcium Calmodulin-binding Cytoplasm Direct protein sequencing Glycoprotein Immunity Inflammatory response Kinase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MLKVTVPSCP | MLKVTVPSCPSSPCSSVTSSTENLVPDYWIDGSKRDPLSDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVKKLIVLDPKKRLTTFQALQHPWVTGKAANFVHMDTAQKKLQEFNARR... | adaptive immune response inflammatory response intracellular signal transduction long-term memory myeloid dendritic cell differentiation neuron-neuron synaptic transmission nucleocytoplasmic transport phosphorylation positive regulation of DNA-templated transcription positive regulation of protein export from nucleus p... |
cell adhesion cell-cell signaling cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to type II interferon chemokine-mediated signaling pathway eosinophil chemotaxis establishment or maintenance of cell polarity G protein-coupled receptor signaling pathway immune response in... | extracellular region; extracellular space | CCR chemokine receptor binding CCR1 chemokine receptor binding CCR5 chemokine receptor binding chemokine activity cytokine activity identical protein binding | Homo sapiens | 3D-structure Chemotaxis Cytokine Disulfide bond Inflammatory response Reference proteome Secreted Signal | MKLCVTVLSL | MKLCVTVLSLLMLVAAFCSPALSAPMGSDPPTACCFSYTARKLPRNFVVDYYETSSLCSQPAVVFQTKRSKQVCADPSESWVQEYVYDLELN | cell adhesion cell-cell signaling cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to type II interferon chemokine-mediated signaling pathway eosinophil chemotaxis establishment or maintenance of cell polarity G protein-coupled receptor signaling pathway immune response in... |
de novo' CTP biosynthetic process CTP biosynthetic process glutamine metabolic process pyrimidine nucleobase biosynthetic process | cytosol | ATP binding CTP synthase activity glutaminase activity identical protein binding metal ion binding | Bacillus subtilis | ATP-binding Glutamine amidotransferase Ligase Magnesium Metal-binding Nucleotide-binding Pyrimidine biosynthesis Reference proteome | MTKYIFVTGG | MTKYIFVTGGVVSSLGKGIVAASLGRLLKNRGLNVTIQKFDPYINVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKFSNVTTGKIYSTVLKKERRGDYLGGTVQVIPHITNELKDRVYRAGKETNADVVITEIGGTVGDIESLPFLEAIRQMKSDIGRENVMYIHCTLVPYIKAAGELKTKPTQHSVKELRSLGIQPNIIVVRTEMPISQDMKDKIALFCDIDTKAVIECEDADNLYSIPLELQKQGLDKLVCEHMKLACKEAEMSEWKELVNKVSNLSQTITIGLVGKYVELPDAYISVVESLRHAGYAF... | de novo' CTP biosynthetic process CTP biosynthetic process glutamine metabolic process pyrimidine nucleobase biosynthetic process cytosol ATP binding CTP synthase activity glutaminase activity identical protein binding metal ion binding Bacillus subtilis ATP-binding Glutamine amidotransferase Ligase Magnesium Metal-bin... |
glycine metabolic process glycogen metabolic process methionine metabolic process methylation one-carbon metabolic process protein homotetramerization regulation of gluconeogenesis S-adenosylhomocysteine metabolic process S-adenosylmethionine metabolic process sarcosine metabolic process | cytosol; methyltransferase complex | folic acid binding glycine binding glycine N-methyltransferase activity identical protein binding S-adenosyl-L-methionine binding S-adenosylmethionine-dependent methyltransferase activity selenol Se-methyltransferase activity | Rattus norvegicus | 3D-structure Acetylation Cytoplasm Direct protein sequencing Folate-binding Methyltransferase Phosphoprotein Reference proteome S-adenosyl-L-methionine Transferase | MVDSVYRTRS | MVDSVYRTRSLGVAAEGIPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCHRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRKEPAFDKWVIEEANWLTLDKDVPAGDGFDAVICLGNSFAHLPDSKGDQSEHRLALKNIASMVRPGGLLVIDHRNYDYILSTGCAPPGKNIYYKSDLTKDITTSVLTVNNKAHMVTLDYTVQVPGAGRDGAPGFSKFRLSYYPHCLASFTELVQEAFGGRCQHSVLGDFKPYRPGQAYVPCYFIHVLKKTG | glycine metabolic process glycogen metabolic process methionine metabolic process methylation one-carbon metabolic process protein homotetramerization regulation of gluconeogenesis S-adenosylhomocysteine metabolic process S-adenosylmethionine metabolic process sarcosine metabolic process cytosol; methyltransferase comp... |
CDP-choline pathway phosphatidylcholine biosynthetic process | membrane; NLS-dependent protein nuclear import complex; nuclear envelope; nucleus | choline-phosphate cytidylyltransferase activity phosphatidylcholine binding | Saccharomyces cerevisiae | Lipid biosynthesis Lipid metabolism Membrane Nucleotidyltransferase Phospholipid biosynthesis Phospholipid metabolism Phosphoprotein Reference proteome Transferase | MANPTTGKSS | MANPTTGKSSIRAKLSNSSLSNLFKKNKNKRQREETEEQDNEDKDESKNQDENKDTQLTPRKRRRLTKEFEEKEARYTNELPKELRKYRPKGFRFNLPPTDRPIRIYADGVFDLFHLGHMKQLEQCKKAFPNVTLIVGVPSDKITHKLKGLTVLTDKQRCETLTHCRWVDEVVPNAPWCVTPEFLLEHKIDYVAHDDIPYVSADSDDIYKPIKEMGKFLTTQRTNGVSTSDIITKIIRDYDKYLMRNFARGATRQELNVSWLKKNELEFKKHINEFRSYFKKNQTNLNNASRDLYFEVREILLKKTLGKKLYSKLIGNEL... | CDP-choline pathway phosphatidylcholine biosynthetic process membrane; NLS-dependent protein nuclear import complex; nuclear envelope; nucleus choline-phosphate cytidylyltransferase activity phosphatidylcholine binding Saccharomyces cerevisiae Lipid biosynthesis Lipid metabolism Membrane Nucleotidyltransferase Phospho... |
chemical synaptic transmission glutamate biosynthetic process glutamine catabolic process intracellular glutamate homeostasis protein homotetramerization regulation of respiratory gaseous exchange by nervous system process suckling behavior | cytosol; mitochondrial matrix; mitochondrion; synapse | glutaminase activity identical protein binding | Rattus norvegicus | Acetylation Alternative splicing ANK repeat Cytoplasm Direct protein sequencing Hydrolase Mitochondrion Phosphoprotein Reference proteome Repeat Transit peptide | MMRLRGSAML | MMRLRGSAMLRELLLRPPAAVGGVLRRTQPLGTLCRRPRGGSRPAAGLVAAARLHPWWGGGGRAKGPGSGGLSSSPSEILQELGKGGTPPQQQQQQQQQPGASPPAAPGPKDSPGETDAFGNSEGKEMVAAGDNKVKQGLLPSLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLKECMDMLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELYESAKKQSGGKVADYIPQLAKFSPDLWGVSVCTVDGQRHSIGDTKVPFCLQSCVKPLKYAIAVNDLGTEYVHRYVGKEPSG... | chemical synaptic transmission glutamate biosynthetic process glutamine catabolic process intracellular glutamate homeostasis protein homotetramerization regulation of respiratory gaseous exchange by nervous system process suckling behavior cytosol; mitochondrial matrix; mitochondrion; synapse glutaminase activity iden... |
mitochondrial electron transport, ubiquinol to cytochrome c mitochondrial respiratory chain complex III assembly | mitochondrial inner membrane; mitochondrial respiratory chain complex III; mitochondrial respiratory chain complex IV; mitochondrion | 2 iron, 2 sulfur cluster binding metal ion binding oxidoreductase activity ubiquinol-cytochrome-c reductase activity | Bos taurus | 2Fe-2S 3D-structure Direct protein sequencing Disulfide bond Electron transport Iron Iron-sulfur Membrane Metal-binding Mitochondrion Mitochondrion inner membrane Reference proteome Respiratory chain Transit peptide Translocase Transmembrane Transmembrane helix Transport | MLSVAARSGP | MLSVAARSGPFAPVLSATSRGVAGALRPLVQAAVPATSESPVLDLKRSVLCRESLRGQAAGRPLVASVSLNVPASVRYSHTDIKVPDFSDYRRPEVLDSTKSSKESSEARKGFSYLVTATTTVGVAYAAKNVVSQFVSSMSASADVLAMSKIEIKLSDIPEGKNMAFKWRGKPLFVRHRTKKEIDQEAAVEVSQLRDPQHDLERVKKPEWVILIGVCTHLGCVPIANAGDFGGYYCPCHGSHYDASGRIRKGPAPLNLEVPSYEFTSDDMVIVG | mitochondrial electron transport, ubiquinol to cytochrome c mitochondrial respiratory chain complex III assembly mitochondrial inner membrane; mitochondrial respiratory chain complex III; mitochondrial respiratory chain complex IV; mitochondrion 2 iron, 2 sulfur cluster binding metal ion binding oxidoreductase activity... |
antigen processing and presentation of exogenous peptide antigen via MHC class I antigen processing and presentation of exogenous peptide antigen via MHC class II negative regulation of fibroblast proliferation protein stabilization | cell junction; cytosol; extracellular region; intracellular membrane-bounded organelle; lysosomal lumen; lysosome | oxidoreductase activity, acting on a sulfur group of donors oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor | Homo sapiens | Direct protein sequencing Disulfide bond Glycoprotein Immunity Lysosome Oxidoreductase Redox-active center Reference proteome Secreted Signal | MTLSPLLLFL | MTLSPLLLFLPPLLLLLDVPTAAVQASPLQALDFFGNGPPVNYKTGNLYLRGPLKKSNAPLVNVTLYYEALCGGCRAFLIRELFPTWLLVMEILNVTLVPYGNAQEQNVSGRWEFKCQHGEEECKFNKVEACVLDELDMELAFLTIVCMEEFEDMERSLPLCLQLYAPGLSPDTIMECAMGDRGMQLMHANAQRTDALQPPHEYVPWVTVNGKPLEDQTQLLTLVCQLYQGKKPDVCPSSTSSLRSVCFK | antigen processing and presentation of exogenous peptide antigen via MHC class I antigen processing and presentation of exogenous peptide antigen via MHC class II negative regulation of fibroblast proliferation protein stabilization cell junction; cytosol; extracellular region; intracellular membrane-bounded organelle;... |
glycogen biosynthetic process glycogen metabolic process phosphorylation | phosphorylase kinase complex | ATP binding calmodulin binding enzyme binding phosphorylase kinase activity protein serine kinase activity tau-protein kinase activity | Rattus norvegicus | ATP-binding Calmodulin-binding Carbohydrate metabolism Glycogen metabolism Kinase Muscle protein Nucleotide-binding Reference proteome Serine/threonine-protein kinase Transferase | MTRDEALPDS | MTRDEALPDSHSAQNFYENYEPKEILGRGVSSVVRRCIHKPTCQEYAVKIIDITGGGSFSSEEVQELREATLKEVDILQKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLTEKETRKIMRALLEVVCTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLQPGEKLREVCGTPSYLAPEIIQCSMDEGHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMDGKYQFGSPEWDDYSDTVKDLVSRFLVVQPQDRCSAEEALAHPFFQEYVVEEVRHFSPRGKFKVICLTVLASVRIYY... | glycogen biosynthetic process glycogen metabolic process phosphorylation phosphorylase kinase complex ATP binding calmodulin binding enzyme binding phosphorylase kinase activity protein serine kinase activity tau-protein kinase activity Rattus norvegicus ATP-binding Calmodulin-binding Carbohydrate metabolism Glycogen m... |
modulation by virus of host chromatin organization phosphorylation suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity | host cell nuclear envelope; host cell nucleus; viral tegument | ATP binding protein serine kinase activity protein serine/threonine kinase activity | Epstein-Barr virus | ATP-binding Early protein Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host IRF3 by virus Inhibition of host RLR pathway by virus Kinase Modulation of host chromatin by virus Nucleotide-binding Reference proteome Serine/threonine-protein kinase Transferase Viral i... | MDVNMAAELS | MDVNMAAELSPTNSSSSGELSVSPEPPRETQAFLGKVTVIDYFTFQHKHLKVTNIDDMTETLYVKLPENMTRCDHLPITCEYLLGRGSYGAVYAHADNATVKLYDSVTELYHELMVCDMIQIGKATAEDGQDKALVDYLSACTSCHALFMPQFRCSLQDYGHWHDGSIEPLVRGFQGLKDAVYFLNRHCGLFHSDISPSNILVDFTDTMWGMGRLVLTDYGTASLHDRNKMLDVRLKSSKGRQLYRLYCQREPFSIAKDTYKPLCLLSKCYILRGAGHIPDPSACGPVGAQTALRLDLQSLGYSLLYGIMHLADSTHKIP... | modulation by virus of host chromatin organization phosphorylation suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity host cell nuclear envelope; host cell nucleus; viral tegument ATP binding protein serine kinase activity protein serine... |
immune response necroptotic signaling pathway negative regulation of protein-containing complex disassembly positive regulation of apoptotic process positive regulation of JUN kinase activity positive regulation of MAP kinase activity positive regulation of NF-kappaB transcription factor activity positive regulation of... | extracellular space; plasma membrane | cytokine activity tumor necrosis factor receptor binding | Capra hircus | Cell membrane Cytokine Disulfide bond Glycoprotein Lipoprotein Membrane Myristate Phosphoprotein Reference proteome Secreted Signal-anchor Transmembrane Transmembrane helix | MSTKSMIRDV | MSTKSMIRDVELAEEVLSKKAGGPQGSRSCWCLSLFSFLLVAGATTLFCLLHFGVIGPQREEQSPAGPSFNRPLVQTLRSSSQASSNKPVAHVVANISAPGQLRWGDSYANALKANGVELKDNQLVVPTDGLYLIYSQVLFRGHGCPSTPLFLTHTISRIAVSYQTKVNILSAIKSPCHRETPEGAEAKPWYEPIYQGGVFQLEKGDRLSAEINQPEYLDYAESGQVYFGIIAL | immune response necroptotic signaling pathway negative regulation of protein-containing complex disassembly positive regulation of apoptotic process positive regulation of JUN kinase activity positive regulation of MAP kinase activity positive regulation of NF-kappaB transcription factor activity positive regulation of... |
intron homing negative regulation of DNA-templated transcription nucleic acid metabolic process | transcription repressor complex | DNA binding DNA-binding transcription repressor activity double-stranded DNA endonuclease activity endonuclease activity sequence-specific DNA binding zinc ion binding | Enterobacteria phage T4 | 3D-structure Endonuclease Hydrolase Intron homing Magnesium Nuclease Reference proteome | MKSGIYQIKN | MKSGIYQIKNTLNNKVYVGSAKDFEKRWKRHFKDLEKGCHSSIKLQRSFNKHGNVFECSILEEIPYEKDLIIERENFWIKELNSKINGYNIADATFGDTCSTHPLKEEIIKKRSETVKAKMLKLGPDGRKALYSKPGSKNGRWNPETHKFCKCGVRIQTSAYTCSKCRNRSGENNSFFNHKHSDITKSKISEKMKGKKPSNIKKISCDGVIFDCAADAARHFKISSGLVTYRVKSDKWNWFYINA | intron homing negative regulation of DNA-templated transcription nucleic acid metabolic process transcription repressor complex DNA binding DNA-binding transcription repressor activity double-stranded DNA endonuclease activity endonuclease activity sequence-specific DNA binding zinc ion binding Enterobacteria phage T4 ... |
killing of cells of another organism | host cell periplasmic space; host cell plasma membrane | DNA binding molecular function inhibitor activity | Enterobacteria phage T4 | 3D-structure Cytolysis Disulfide bond DNA-binding Host cell lysis by virus Host periplasm Reference proteome Signal Viral release from host cell | MALKATALFA | MALKATALFAMLGLSFVLSPSIEANVDPHFDKFMESGIRHVYMLFENKSVESSEQFYSFMRTTYKNDPCSSDFECIERGAEMAQSYARIMNIKLETE | killing of cells of another organism host cell periplasmic space; host cell plasma membrane DNA binding molecular function inhibitor activity Enterobacteria phage T4 3D-structure Cytolysis Disulfide bond DNA-binding Host cell lysis by virus Host periplasm Reference proteome Signal Viral release from host cell MALKATALF... |
cellular response to calcium ion cellular response to hormone stimulus female pregnancy positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II response to cAMP response to corticosterone response to mechanical stimulus response to progesterone response to xenobiotic s... | intracellular membrane-bounded organelle; nucleoplasm; nucleus | DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific double-stranded DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA bin... | Mus musculus | Alternative splicing Disulfide bond DNA-binding Nucleus Phosphoprotein Reference proteome | MFQAFPGDYD | MFQAFPGDYDSGSRCSSSPSAESQYLSSVDSFGSPPTAAASQECAGLGEMPGSFVPTVTAITTSQDLQWLVQPTLISSMAQSQGQPLASQPPAVDPYDMPGTSYSTPGLSAYSTGGASGSGGPSTSTTTSGPVSARPARARPRRPREETLTPEEEEKRRVRRERNKLAAAKCRNRRRELTDRLQAETDQLEEEKAELESEIAELQKEKERLEFVLVAHKPGCKIPYEEGPGPGPLAEVRDLPGSTSAKEDGFGWLLPPPPPPPLPFQSSRDAPPNLTASLFTHSEVQVLGDPFPVVSPSYTSSFVLTCPEVSAFAGAQRT... | cellular response to calcium ion cellular response to hormone stimulus female pregnancy positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II response to cAMP response to corticosterone response to mechanical stimulus response to progesterone response to xenobiotic s... |
camera-type eye development cartilage condensation embryonic skeletal system morphogenesis extracellular matrix organization muscle cell fate commitment muscle organ development muscle tissue morphogenesis ossification positive regulation of myoblast differentiation positive regulation of skeletal muscle fiber developm... | chromatin; nucleoplasm; RNA polymerase II transcription regulator complex | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding | Homo sapiens | 3D-structure Activator Developmental protein Differentiation Disease variant DNA-binding Myogenesis Nucleus Reference proteome Transcription Transcription regulation | MDVMDGCQFS | MDVMDGCQFSPSEYFYDGSCIPSPEGEFGDEFVPRVAAFGAHKAELQGSDEDEHVRAPTGHHQAGHCLMWACKACKRKSTTMDRRKAATMRERRRLKKVNQAFETLKRCTTTNPNQRLPKVEILRNAIRYIESLQELLREQVENYYSLPGQSCSEPTSPTSNCSDGMPECNSPVWSRKSSTFDSIYCPDVSNVYATDKNSLSSLDCLSNIVDRITSSEQPGLPLQDLASLSPVASTDSQPATPGASSSRLIYHVL | camera-type eye development cartilage condensation embryonic skeletal system morphogenesis extracellular matrix organization muscle cell fate commitment muscle organ development muscle tissue morphogenesis ossification positive regulation of myoblast differentiation positive regulation of skeletal muscle fiber developm... |
circadian temperature homeostasis compound eye morphogenesis compound eye photoreceptor cell differentiation compound eye photoreceptor fate commitment entrainment of circadian clock entrainment of circadian clock by photoperiod photoreceptor cell differentiation positive regulation of transcription by RNA polymerase I... | nucleus | DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding | Drosophila melanogaster | Alternative splicing DNA-binding Metal-binding Nucleus Reference proteome Repeat Sensory transduction Transcription Transcription regulation Vision Zinc Zinc-finger | MGLLYKGSKL | MGLLYKGSKLLNTILDSLEDQEGGAMYISCDVSNGGPVEPETGYVPNNPLFGLALDSPQQECAASCVGCLSCQGSTALPISSLTSSDFDCGGCFDPTIGVGVGIGGGHIQISTTPPASSGNGSSNNGAGGGSSGNHGYWSTDEMASTFPGLPPLDIDPLPSLFPFSPCGASYNFAAGNPHQAASLSYTVHPHQMLISPNSHNHGQMHSQHQQHQHQQSQVQASHVGNSLLQSSGGNNIGSNGSAGGVANAASCYYETSAGTAAPPPPPAAAMYPSMSVNVSMNMTMHHGYGAGDAGGVPMQCSQMNWTPPSNSTSAAAAA... | circadian temperature homeostasis compound eye morphogenesis compound eye photoreceptor cell differentiation compound eye photoreceptor fate commitment entrainment of circadian clock entrainment of circadian clock by photoperiod photoreceptor cell differentiation positive regulation of transcription by RNA polymerase I... |
cell division mitotic cell cycle phase transition regulation of cell cycle G1/S phase transition regulation of protein phosphorylation regulation of transcription by RNA polymerase II traversing start control point of mitotic cell cycle vacuole fusion, non-autophagic vacuole organization | cyclin-dependent protein kinase holoenzyme complex; cytoplasm; nucleus; spindle pole body | cyclin-dependent protein serine/threonine kinase regulator activity | Saccharomyces cerevisiae | Cell cycle Cell division Cyclin Reference proteome | MAILKDTIIR | MAILKDTIIRYANARYATASGTSTATAASVSAASCPNLPLLLQKRRAIASAKSKNPNLVKRELQAHHSAISEYNNDQLDHYFRLSHTERPLYNLTNFNSQPQVNPKMRFLIFDFIMYCHTRLNLSTSTLFLTFTILDKYSSRFIIKSYNYQLLSLTALWISSKFWDSKNRMATLKVLQNLCCNQYSIKQFTTMEMHLFKSLDWSICQSATFDSYIDIFLFQSTSPLSPGVVLSAPLEAFIQQKLALLNNAAGTAINKSSSSQGPSLNINEIKLGAIMLCELASFNLELSFKYDRSLIALGAINLIKLSLNYYNSNLWENI... | cell division mitotic cell cycle phase transition regulation of cell cycle G1/S phase transition regulation of protein phosphorylation regulation of transcription by RNA polymerase II traversing start control point of mitotic cell cycle vacuole fusion, non-autophagic vacuole organization cyclin-dependent protein kinase... |
cellular response to cytokine stimulus cellular response to macrophage colony-stimulating factor stimulus inflammatory response innate immune response osteoclast differentiation peptidyl-tyrosine phosphorylation positive regulation of cell migration positive regulation of cell population proliferation positive regulati... | cell surface; CSF1-CSF1R complex; plasma membrane; receptor complex | ATP binding cytokine binding growth factor binding macrophage colony-stimulating factor receptor activity | Felis catus | ATP-binding Cell membrane Disulfide bond Glycoprotein Immunity Immunoglobulin domain Inflammatory response Innate immunity Kinase Membrane Nucleotide-binding Phosphoprotein Proto-oncogene Receptor Reference proteome Repeat Signal Transferase Transmembrane Transmembrane helix Tyrosine-protein kinase Ubl conjugation | MGPRALLVLL | MGPRALLVLLVATAWHAQGVPVIQPSGPELVVEPGTTVTLRCVGNGSVEWDGPISPHWNLDLDPPSSILTTNNATFQNTGTYHCTEPGNPQGGNATIHLYVKDPARPWKVLAQEVTVLEGQDALLPCLLTDPALEAGVSLVRVRGRPVLRQTNYSFSPWHGFTIHKAKFIENHVYQCSARVDGRTVTSMGIWLKVQKDISGPATLTLEPAELVRIQGEAAQIVCSASNIDVNFDVSLRHGDTKLTISQQSDFHDNRYQKVLTLNLDHVSFQDAGNYSCTATNAWGNHSASMVFRVVESAYLNLTSEQSLLQEVTVGEKVD... | cellular response to cytokine stimulus cellular response to macrophage colony-stimulating factor stimulus inflammatory response innate immune response osteoclast differentiation peptidyl-tyrosine phosphorylation positive regulation of cell migration positive regulation of cell population proliferation positive regulati... |
B cell homeostasis B cell proliferation cell morphogenesis hemopoiesis immune response regulation of cell size | endoplasmic reticulum; external side of plasma membrane; extracellular space; plasma membrane | signaling receptor activity | Mus musculus | Disulfide bond Endoplasmic reticulum Immunoglobulin domain Reference proteome Signal | MAWTSVLLML | MAWTSVLLMLLAYLTGCGPQPMVHQPPLASSSLGATIRLSCTLSNDHNIGIYSIYWYQQRPGHPPRFLLRYFSHSDKHQGPDIPPRFSGSKDTTRNLGYLSISELQPEDEAVYYCAVGLRSQEKKRMEREWEGEKSYTDLGS | B cell homeostasis B cell proliferation cell morphogenesis hemopoiesis immune response regulation of cell size endoplasmic reticulum; external side of plasma membrane; extracellular space; plasma membrane signaling receptor activity Mus musculus Disulfide bond Endoplasmic reticulum Immunoglobulin domain Reference prote... |
anterior/posterior axis specification, embryo negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II skeletal system morphogenesis | chromatin; nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Homo sapiens | Alternative splicing Developmental protein DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation | MSSYFVNPLY | MSSYFVNPLYSKYKAAAAAAAAAGEAINPTYYDCHFAPEVGGRHAAAAAALQLYGNSAAGFPHAPPQAHAHPHPSPPPSGTGCGGREGRGQEYFHPGGGSPAAAYQAAPPPPPHPPPPPPPPPCGGIACHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCKSSSGNIGEDPDHLNQSSSPSQMFPWMRPQAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTERQVKIWFQNRRMKWKKENNKDKFPVSRQEVKDGETKKEAQELEEDRAEGLTN | anterior/posterior axis specification, embryo negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II skeletal system morphogenesis chromatin; nucleus DNA-binding transcription activator activity, RNA polymerase... |
angiogenesis cellular response to epidermal growth factor stimulus cellular response to leukemia inhibitory factor cellular response to lipopolysaccharide endocytosis liver regeneration negative regulation of apoptotic process negative regulation of insulin receptor signaling pathway negative regulation of translation ... | cell cortex; cell surface; cornified envelope; dense fibrillar component; fibrillar center; nucleolus; nucleoplasm; nucleus; ribonucleoprotein complex; spliceosomal complex | calcium ion binding DNA topoisomerase binding ErbB-4 class receptor binding histone binding identical protein binding insulin receptor substrate binding laminin binding mRNA 5'-UTR binding PH domain binding RNA binding rRNA primary transcript binding selenocysteine insertion sequence binding sequence-specific DNA bindi... | Rattus norvegicus | Acetylation Cytoplasm DNA-binding Isopeptide bond Methylation Nucleus Phosphoprotein Reference proteome Repeat RNA-binding Ubl conjugation | MVKLAKAGKT | MVKLAKAGKTHGESKKMAPPPKEVEEDSEDEEMSEDEDDSSGEEEVVIPQKKGKKATTTPAKKVVVSQTKKAAVPTPAKKAAVTPGKKAAATPAKKAVTPAKVVPTPGKKGAAQAKALVPTPGKKGAVTPAKGAKNGKNAKKEDSDEDEDEEDEDDSDEDEDEEDEFEPPVVKGVKPAKAAPAAPASEDEDEEDDDDEDDDDDDEEEEEEDDSEEEVMEITPAKGKKTPAKVVPVKAKSVAEEEEDDEDDEDEEEDEDEEDEEDDEDEDEEEEEEPVKAAPGKRKKEMTKQKEAPEAKKQKIEGSEPTTPFNLFIGNLNP... | angiogenesis cellular response to epidermal growth factor stimulus cellular response to leukemia inhibitory factor cellular response to lipopolysaccharide endocytosis liver regeneration negative regulation of apoptotic process negative regulation of insulin receptor signaling pathway negative regulation of translation ... |
cell surface receptor signaling pathway Fc-epsilon receptor signaling pathway immune response positive regulation of mast cell degranulation protein kinase C-activating G protein-coupled receptor signaling pathway regulation of release of sequestered calcium ion into cytosol signal transduction | endosome; external side of plasma membrane; Fc-epsilon receptor I complex; plasma membrane | IgE binding phosphoprotein binding protein kinase binding SH2 domain binding | Rattus norvegicus | Direct protein sequencing Disulfide bond IgE-binding protein Membrane Phosphoprotein Receptor Reference proteome Transmembrane Transmembrane helix | MDTENKSRAD | MDTENKSRADLALPNPQESPSAPDIELLEASPPAKALPEKPASPPPQQTWQSFLKKELEFLGVTQVLVGLICLCFGTVVCSTLQTSDFDDEVLLLYRAGYPFWGAVLFVLSGFLSIMSERKNTLYLVRGSLGANIVSSIAAGLGIAILILNLSNNSAYMNYCKDITEDDGCFVTSFITELVLMLLFLTILAFCSAVLLIIYRIGQEFERSKVPDDRLYEELHVYSPIYSALEDTREASAPVVS | cell surface receptor signaling pathway Fc-epsilon receptor signaling pathway immune response positive regulation of mast cell degranulation protein kinase C-activating G protein-coupled receptor signaling pathway regulation of release of sequestered calcium ion into cytosol signal transduction endosome; external side ... |
cellular response to epidermal growth factor stimulus epidermal growth factor receptor signaling pathway learning or memory phosphorylation | endoplasmic reticulum membrane; endosome membrane; Golgi membrane; nuclear membrane; nucleus; plasma membrane | ATP binding protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity | Gallus gallus | ATP-binding Cell membrane Disulfide bond Endoplasmic reticulum Endosome Glycoprotein Golgi apparatus Kinase Membrane Nucleotide-binding Nucleus Phosphoprotein Receptor Reference proteome Signal Transferase Transmembrane Transmembrane helix Tyrosine-protein kinase | MGVRSPLSAS | MGVRSPLSASGPRGAAVLVLLLLGVALCSAVEEKKVCQGTNNKLTQLGHVEDHFTSLQRMYNNCEVVLSNLEITYVEHNRDLTFLKTIQEVAGYVLIALNMVDVIPLENLQIIRGNVLYDNSFALAVLSNYHMNKTQGLRELPMKRLSEILNGGVKISNNPKLCNMDTVLWNDIIDTSRKPLTVLDFASNLSSCPKCHPNCTEDHCWGAGEQNCQTLTKVICAQQCSGRCRGKVPSDCCHNQCAAGCTGPRESDCLACRKFRDDATCKDTCPPLVLYNPTTYQMDVNPEGKYSFGATCVRECPHNYVVTDHGSCVRSCNT... | cellular response to epidermal growth factor stimulus epidermal growth factor receptor signaling pathway learning or memory phosphorylation endoplasmic reticulum membrane; endosome membrane; Golgi membrane; nuclear membrane; nucleus; plasma membrane ATP binding protein tyrosine kinase activity transmembrane receptor pr... |
DNA-templated transcription initiation negative regulation of DNA-templated transcription nucleolar large rRNA transcription by RNA polymerase I positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase III RNA polymerase I preinitiation complex assembly RNA polymerase II p... | nucleoplasm; nucleus; protein-containing complex; transcription factor TFIIA complex; transcription factor TFIID complex; transcription factor TFIIIB complex; transcription regulator complex | chromatin binding disordered domain specific binding DNA binding, bending DNA-binding transcription factor binding RNA polymerase I general transcription initiation factor binding RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase II general transcription initiation factor activity RNA polymer... | Saccharomyces cerevisiae | 3D-structure Direct protein sequencing DNA-binding Nucleus Reference proteome Repeat Transcription | MADEERLKEF | MADEERLKEFKEANKIVFDPNTRQVWENQNRDGTKPATTFQSEEDIKRAAPESEKDTSATSGIVPTLQNIVATVTLGCRLDLKTVALHARNAEYNPKRFAAVIMRIREPKTTALIFASGKMVVTGAKSEDDSKLASRKYARIIQKIGFAAKFTDFKIQNIVGSCDVKFPIRLEGLAFSHGTFSSYEPELFPGLIYRMVKPKIVLLIFVSGKIVLTGAKQREEIYQAFEAIYPVLSEFRKM | DNA-templated transcription initiation negative regulation of DNA-templated transcription nucleolar large rRNA transcription by RNA polymerase I positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase III RNA polymerase I preinitiation complex assembly RNA polymerase II p... |
negative regulation of MAPK cascade positive regulation of apoptotic process in another organism protein homooligomerization | extracellular region; host cell cytosol; host cell endosome membrane; host cell plasma membrane; membrane | identical protein binding metal ion binding toxin activity | Bacillus anthracis | 3D-structure Calcium Cleavage on pair of basic residues Host cell membrane Host endosome Host membrane Membrane Metal-binding Plasmid Reference proteome Secreted Signal Toxin Transmembrane Transmembrane beta strand Virulence | MKKRKVLIPL | MKKRKVLIPLMALSTILVSSTGNLEVIQAEVKQENRLLNESESSSQGLLGYYFSDLNFQAPMVVTSSTTGDLSIPSSELENIPSENQYFQSAIWSGFIKVKKSDEYTFATSADNHVTMWVDDQEVINKASNSNKIRLEKGRLYQIKIQYQRENPTEKGLDFKLYWTDSQNKKEVISSDNLQLPELKQKSSNSRKKRSTSAGPTVPDRDNDGIPDSLEVEGYTVDVKNKRTFLSPWISNIHEKKGLTKYKSSPEKWSTASDPYSDFEKVTGRIDKNVSPEARHPLVAAYPIVHVDMENIILSKNEDQSTQNTDSQTRTISK... | negative regulation of MAPK cascade positive regulation of apoptotic process in another organism protein homooligomerization extracellular region; host cell cytosol; host cell endosome membrane; host cell plasma membrane; membrane identical protein binding metal ion binding toxin activity Bacillus anthracis3D-structure... |
cellular response to lipopolysaccharide negative regulation of peptidase activity regulation of sensory perception of pain | extracellular region | endopeptidase inhibitor activity hormone activity peptidase inhibitor activity | Rattus norvegicus | Cleavage on pair of basic residues Direct protein sequencing Glycoprotein Hormone Reference proteome Secreted Signal | MKSLYLIFGL | MKSLYLIFGLWILLACFQSGEGVRGPRRQHNPRRQQDPSTLPHYLGLQPDPNGGQIGVTITIPLNLQPPRVLVNLPGFITGPPLVVQGTTEYQYQWQLTAPDPTPLSNPPTQLHSTEQANTKTDAKISNTTATTQNSTDIFEGGGK | cellular response to lipopolysaccharide negative regulation of peptidase activity regulation of sensory perception of pain extracellular region endopeptidase inhibitor activity hormone activity peptidase inhibitor activity Rattus norvegicus Cleavage on pair of basic residues Direct protein sequencing Glycoprotein Hormo... |
acetyl-CoA metabolic process cellular response to hypoxia fatty acid beta-oxidation negative regulation of mitochondrial membrane permeability involved in apoptotic process negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | mitochondrial matrix; mitochondrion | acetyl-CoA C-acetyltransferase activity acetyl-CoA C-acyltransferase activity acetyl-CoA hydrolase activity acyl-CoA hydrolase activity myristoyl-CoA hydrolase activity palmitoyl-CoA hydrolase activity | Rattus norvegicus | Acetylation Acyltransferase Fatty acid metabolism Hydrolase Lipid metabolism Mitochondrion Phosphoprotein Reference proteome Transferase Transit peptide | MALLRGVFIV | MALLRGVFIVAAKRTPFGAYGGLLKDFTATDLTEFAARAALSAGKVPPETIDSVIVGNVMQSSSDAAYLARHVGLRVGVPTETGALTLNRLCGSGFQSIVSGCQEICSKDAEVVLCGGTESMSQSPYSVRNVRFGTKFGLDLKLEDTLWAGLTDQHVKLPMGMTAENLAAKYNISREDCDRYALQSQQRWKAANEAGYFNEEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQNLPPVFKKEGTVTAGNASGMSDGAGVVIIASEDAVKKHNFTPLARVVGYFVSGCDPAIMGIGPVPAITGALKKAGLSLKDMDLIDVN... | acetyl-CoA metabolic process cellular response to hypoxia fatty acid beta-oxidation negative regulation of mitochondrial membrane permeability involved in apoptotic process negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway mitochondrial matrix; mitochondrion ac... |
de novo' pyrimidine nucleobase biosynthetic process 'de novo' UMP biosynthetic process cellular response to xenobiotic stimulus female pregnancy lactation pyrimidine nucleobase biosynthetic process UDP biosynthetic process UMP biosynthetic process | cytoplasm; nucleus | identical protein binding orotate phosphoribosyltransferase activity orotidine-5'-phosphate decarboxylase activity | Mus musculus | Decarboxylase Glycosyltransferase Lyase Multifunctional enzyme Phosphoprotein Pyrimidine biosynthesis Reference proteome Transferase | MEVASQALGP | MEVASQALGPLVTELYDVQAFKFGSFVLKSGLSSPVYIDLRGIVSRPRLLSQVADILFQTAKNAGISFDSVCGVPYTALPLATVICSANHIPMLIRRKETKDYGTKRLVEGEINPGQTCLVIEDVVTSGASVLETVEVLQKEGLKVTDAIVLLDREQGGKDKLQAQGIRLHAVCTLSQMLEILQQQEKIDADMVGRVKRFIQENVFSAANHNGLPPPEKKACKELSFGARAELPGTHPLASKLLRLMQKKETNLCLSADVSEARELLQLADALGPSICMLKTHVDILNDFTLDVMEELTALAKRHEFLIFEDRKFADIGN... | de novo' pyrimidine nucleobase biosynthetic process 'de novo' UMP biosynthetic process cellular response to xenobiotic stimulus female pregnancy lactation pyrimidine nucleobase biosynthetic process UDP biosynthetic process UMP biosynthetic process cytoplasm; nucleus identical protein binding orotate phosphoribosyltrans... |
methionine catabolic process one-carbon metabolic process protein homotetramerization protein-containing complex assembly S-adenosylmethionine biosynthetic process | cytosol; methionine adenosyltransferase complex; nuclear matrix | ADP binding amino acid binding ATP binding identical protein binding magnesium ion binding methionine adenosyltransferase activity | Rattus norvegicus | 3D-structure ATP-binding Disulfide bond Magnesium Metal-binding Nucleotide-binding One-carbon metabolism Potassium Reference proteome S-nitrosylation Transferase | MNGPVDGLCD | MNGPVDGLCDHSLSEEGAFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGEITSMAMIDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIVLAHKLNTRMADLRRSGVLPWLRPDSKTQVTVQYVQDNGAVIPVRVHTIVISVQHNEDITLEAMREALKEQVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCRRVLVQVS... | methionine catabolic process one-carbon metabolic process protein homotetramerization protein-containing complex assembly S-adenosylmethionine biosynthetic process cytosol; methionine adenosyltransferase complex; nuclear matrix ADP binding amino acid binding ATP binding identical protein binding magnesium ion binding m... |
DNA-templated transcription initiation negative regulation of DNA-templated transcription regulation of DNA-templated transcription initiation | cytoplasm; cytosolic DNA-directed RNA polymerase complex; sigma factor antagonist complex | bacterial-type RNA polymerase core enzyme binding DNA binding sigma factor activity | Escherichia coli | 3D-structure Cytoplasm DNA-binding Reference proteome Sigma factor Stress response Transcription Transcription regulation | MSQNTLKVHD | MSQNTLKVHDLNEDAEFDENGVEVFDEKALVEQEPSDNDLAEEELLSQGATQRVLDATQLYLGEIGYSPLLTAEEEVYFARRALRGDVASRRRMIESNLRLVVKIARRYGNRGLALLDLIEEGNLGLIRAVEKFDPERGFRFSTYATWWIRQTIERAIMNQTRTIRLPIHIVKELNVYLRTARELSHKLDHEPSAEEIAEQLDKPVDDVSRMLRLNERITSVDTPLGGDSEKALLDILADEKENGPEDTTQDDDMKQSIVKWLFELNAKQREVLARRFGLLGYEAATLEDVGREIGLTRERVRQIQVEGLRRLREILQTQ... | DNA-templated transcription initiation negative regulation of DNA-templated transcription regulation of DNA-templated transcription initiation cytoplasm; cytosolic DNA-directed RNA polymerase complex; sigma factor antagonist complex bacterial-type RNA polymerase core enzyme binding DNA binding sigma factor activity Esc... |
actin crosslink formation actin cytoskeleton organization cell migration cell motility chemotaxis to cAMP hyperosmotic response lamellipodium assembly phagocytosis phototaxis pseudopodium assembly regulation of pseudopodium assembly response to cAMP sorocarp development thermotaxis | anterior cell cortex; cell cortex; cell leading edge; cortical actin cytoskeleton; cytoplasm; extracellular matrix; lateral cell cortex; macropinocytic cup; phagocytic cup; plasma membrane; posterior cell cortex; pseudopodium | actin filament binding mitogen-activated protein kinase binding protein kinase B binding small GTPase binding | Dictyostelium discoideum | 3D-structure Actin-binding Direct protein sequencing Reference proteome Repeat | MAAAPSGKTW | MAAAPSGKTWIDVQKKTFTGWANNYLKERILKIEDLATSLEDGVLLINLLEIISSKKILKYNKAPKIRMQKIENNNMAVNFIKSEGLKLVGIGAEDIVDSQLKLILGLIWTLILRYQIQMSESDNSPKAALLEWVRKQVAPYKVVVNNFTDSWCDGRVLSALTDSLKPGVREMSTLTGDAVQDIDRSMDIALEEYEIPKIMDANDMNSLPDELSVITYVSYFRDYALNKEKRDADALAALEKKRRETSDASKVEVYGPGVEGGFVNKSADFHIKAVNYYGEPLANGGEGFTVSVVGADGVEVPCKLVDNKNGIYDASYTA... | actin crosslink formation actin cytoskeleton organization cell migration cell motility chemotaxis to cAMP hyperosmotic response lamellipodium assembly phagocytosis phototaxis pseudopodium assembly regulation of pseudopodium assembly response to cAMP sorocarp development thermotaxis anterior cell cortex; cell cortex; ce... |
mRNA splicing, via spliceosome | cytoplasm; nuclear speck; nucleolus; nucleus; protein-containing complex | DNA binding RNA binding sequence-specific DNA binding | Drosophila melanogaster | DNA-binding Nucleus Phosphoprotein Reference proteome Repeat RNA-binding | MAQKKAVTVK | MAQKKAVTVKGKKATNGEEKPLAKRVTKSTKVQEEETVVPQSPSKKSRKQPVKEVPQFSEEDESDVEEQNDEQPGDDSDFETEEAAGLIDDEAEEDEEYNSDDEEDDDDDELEPGEVSKSEGADEVDESDDDEEAPVEKPVSKKSEKANSEKSEENRGIPKVKVGKIPLGTPKNQIVFVTNLPNEYLHKDLVALFAKFGRLSALQRFTNLNGNKSVLIAFDTSTGAEAVLQAKPKALTLGDNVLSVSQPRNKEENNERTVVVGLIGPNITKDDLKTFFEKVAPVEAVTISSNRLMPRAFVRLASVDDIPKALKLHSTELF... | mRNA splicing, via spliceosome cytoplasm; nuclear speck; nucleolus; nucleus; protein-containing complex DNA binding RNA binding sequence-specific DNA binding Drosophila melanogaster DNA-binding Nucleus Phosphoprotein Reference proteome Repeat RNA-binding MAQKKAVTVK MAQKKAVTVKGKKATNGEEKPLAKRVTKSTKVQEEETVVPQSPSKKSRKQPVKE... |
autophagosome maturation cellular response to starvation chaperone-mediated autophagy lysosomal lumen acidification lysosomal protein catabolic process muscle cell cellular homeostasis negative regulation of NLRP3 inflammasome complex assembly negative regulation of protein-containing complex assembly protein catabolic... | autolysosome; autophagosome membrane; azurophil granule membrane; chaperone-mediated autophagy translocation complex; extracellular exosome; extracellular space; ficolin-1-rich granule membrane; intracellular membrane-bounded organelle; late endosome; late endosome membrane; lysosomal lumen; lysosomal membrane; lysosom... | enzyme binding ion channel inhibitor activity protein domain specific binding signaling adaptor activity | Homo sapiens | 3D-structure Alternative splicing Autophagy Cell membrane Cytoplasmic vesicle Direct protein sequencing Disease variant Disulfide bond Endosome Glycogen storage disease Glycoprotein Lysosome Membrane Reference proteome Signal Transmembrane Transmembrane helix | MVCFRLFPVP | MVCFRLFPVPGSGLVLVCLVLGAVRSYALELNLTDSENATCLYAKWQMNFTVRYETTNKTYKTVTISDHGTVTYNGSICGDDQNGPKIAVQFGPGFSWIANFTKAASTYSIDSVSFSYNTGDNTTFPDAEDKGILTVDELLAIRIPLNDLFRCNSLSTLEKNDVVQHYWDVLVQAFVQNGTVSTNEFLCDKDKTSTVAPTIHTTVPSPTTTPTPKEKPEAGTYSVNNGNDTCLLATMGLQLNITQDKVASVININPNTTHSTGSCRSHTALLRLNSSTIKYLDFVFAVKNENRFYLKEVNISMYLVNGSVFSIANNNLSY... | autophagosome maturation cellular response to starvation chaperone-mediated autophagy lysosomal lumen acidification lysosomal protein catabolic process muscle cell cellular homeostasis negative regulation of NLRP3 inflammasome complex assembly negative regulation of protein-containing complex assembly protein catabolic... |
cell cycle cellular senescence circadian behavior DNA damage response entrainment of circadian clock by photoperiod negative regulation of cell growth negative regulation of DNA-templated transcription nucleotide-excision repair oligodendrocyte apoptotic process positive regulation of apoptotic process positive regulat... | centrosome; cytoplasm; endoplasmic reticulum; mitochondrial matrix; mitochondrion; nucleolus; nucleus; PML body | ATP-dependent DNA/DNA annealing activity copper ion binding DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific promoter-specific chromatin binding RNA polymerase II cis-regulatory region sequence-specific DNA binding | Chlorocebus aethiops | Acetylation Activator Apoptosis Biological rhythms Cell cycle Cytoplasm Cytoskeleton DNA-binding Endoplasmic reticulum Isopeptide bond Metal-binding Methylation Mitochondrion Necrosis Nucleus Phosphoprotein Repressor Transcription Transcription regulation Tumor suppressor Ubl conjugation Zinc | MEEPQSDPSI | MEEPQSDPSIEPPLSQETFSDLWKLLPENNVLSPLPSQAVDDLMLSPDDLAQWLTEDPGPDEAPRMSEAAPHMAPTPAAPTPAAPAPAPSWPLSSSVPSQKTYHGSYGFRLGFLHSGTAKSVTCTYSPDLNKMFCQLAKTCPVQLWVDSTPPPGSRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHLIRVEGNLRVEYSDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENFRKKGEPCHELPPGSTKRALPNNTSSSPQPKK... | cell cycle cellular senescence circadian behavior DNA damage response entrainment of circadian clock by photoperiod negative regulation of cell growth negative regulation of DNA-templated transcription nucleotide-excision repair oligodendrocyte apoptotic process positive regulation of apoptotic process positive regulat... |
cellular hyperosmotic response DNA damage response trehalose catabolic process | outer membrane-bounded periplasmic space | alpha,alpha-trehalase activity | Escherichia coli | 3D-structure Direct protein sequencing Glycosidase Hydrolase Periplasm Reference proteome Signal | MKSPAPSRPQ | MKSPAPSRPQKMALIPACIFLCFAALSVQAEETPVTPQPPDILLGPLFNDVQNAKLFPDQKTFADAVPNSDPLMILADYRMQQNQSGFDLRHFVNVNFTLPKEGEKYVPPEGQSLREHIDGLWPVLTRSTENTEKWDSLLPLPEPYVVPGGRFREVYYWDSYFTMLGLAESGHWDKVADMVANFAHEIDTYGHIPNGNRSYYLSRSQPPFFALMVELLAQHEGDAALKQYLPQMQKEYAYWMDGVENLQAGQQEKRVVKLQDGTLLNRYWDDRDTPRPESWVEDIATAKSNPNRPATEIYRDLRSAAASGWDFSSRWMDN... | cellular hyperosmotic response DNA damage response trehalose catabolic process outer membrane-bounded periplasmic space alpha,alpha-trehalase activity Escherichia coli 3D-structure Direct protein sequencing Glycosidase Hydrolase Periplasm Reference proteome Signal MKSPAPSRPQ MKSPAPSRPQKMALIPACIFLCFAALSVQAEETPVTPQPPDILL... |
cell wall organization teichoic acid biosynthetic process | plasma membrane | CDP-glycerol glycerophosphotransferase activity | Bacillus subtilis | Cell membrane Cell wall biogenesis/degradation Membrane Reference proteome Teichoic acid biosynthesis Transferase | MSLVVDTNKR | MSLVVDTNKRKQKGKSFYTEEQKKVMIENTVIKCILKSLKNNLGSLELLISIDSEHQFLEDYQLFLKLKERRSGTESEFPLQNTGSLEYKTEINAHVLPMPVEMGQTYDFYVEFRKKYEDAEQEPLLKRLSAEVNSIERAFHVDQTTELLILPYTTDKGNFSIKVKREAKIIRFDQIEISSEEISITGYAGYLSSENQYRIKNLNLILKKGGETPIEEKFPIKLERKTHGLENMRADGFVPELYDFEVKVPLKEIPFSNEKRYVYRLFMEYICNDDEGTDIQFNSTALVLGDRKNKLKGLVSIIKTNNAPVRYEVFKKKK... | cell wall organization teichoic acid biosynthetic process plasma membrane CDP-glycerol glycerophosphotransferase activity Bacillus subtilis Cell membrane Cell wall biogenesis/degradation Membrane Reference proteome Teichoic acid biosynthesis Transferase MSLVVDTNKR MSLVVDTNKRKQKGKSFYTEEQKKVMIENTVIKCILKSLKNNLGSLELLISIDSE... |
defense response to bacterium defense response to fungus killing of cells of another organism | extracellular region | ion channel inhibitor activity potassium channel regulator activity toxin activity | Leiurus hebraeus | 3D-structure Antibiotic Antimicrobial Calcium-activated potassium channel impairing toxin Direct protein sequencing Disulfide bond Fungicide Ion channel impairing toxin Neurotoxin Potassium channel impairing toxin Pyrrolidone carboxylic acid Secreted Signal Toxin Voltage-gated potassium channel impairing toxin | MKILSVLLLA | MKILSVLLLALIICSIVGWSEAQFTNVSCTTSKECWSVCQRLHNTSRGKCMNKKCRCYS | defense response to bacterium defense response to fungus killing of cells of another organism extracellular region ion channel inhibitor activity potassium channel regulator activity toxin activity Leiurus hebraeus 3D-structure Antibiotic Antimicrobial Calcium-activated potassium channel impairing toxin Direct protein... |
cell migration mRNA catabolic process regulation of angiogenesis regulation of Arp2/3 complex-mediated actin nucleation | angiogenin-PRI complex; cytosol; extracellular exosome; lamellipodium; nucleoplasm; plasma membrane | ribonuclease inhibitor activity | Homo sapiens | 3D-structure Acetylation Cytoplasm Direct protein sequencing Leucine-rich repeat Phosphoprotein Reference proteome Repeat | MSLDIQSLDI | MSLDIQSLDIQCEELSDARWAELLPLLQQCQVVRLDDCGLTEARCKDISSALRVNPALAELNLRSNELGDVGVHCVLQGLQTPSCKIQKLSLQNCCLTGAGCGVLSSTLRTLPTLQELHLSDNLLGDAGLQLLCEGLLDPQCRLEKLQLEYCSLSAASCEPLASVLRAKPDFKELTVSNNDINEAGVRVLCQGLKDSPCQLEALKLESCGVTSDNCRDLCGIVASKASLRELALGSNKLGDVGMAELCPGLLHPSSRLRTLWIWECGITAKGCGDLCRVLRAKESLKELSLAGNELGDEGARLLCETLLEPGCQLESLWV... | cell migration mRNA catabolic process regulation of angiogenesis regulation of Arp2/3 complex-mediated actin nucleation angiogenin-PRI complex; cytosol; extracellular exosome; lamellipodium; nucleoplasm; plasma membrane ribonuclease inhibitor activity Homo sapiens 3D-structure Acetylation Cytoplasm Direct protein seque... |
cartilage condensation cell differentiation collagen fibril organization dorsal/ventral pattern formation ossification positive regulation of cartilage development protein processing proteolysis skeletal system development | extracellular region; extracellular space; Golgi apparatus; vesicle | calcium ion binding cytokine activity growth factor activity identical protein binding metalloendopeptidase activity metallopeptidase activity peptidase activity serine-type endopeptidase activity zinc ion binding | Homo sapiens | 3D-structure Alternative splicing Calcium Chondrogenesis Cleavage on pair of basic residues Cytokine Developmental protein Differentiation Disease variant Disulfide bond EGF-like domain Extracellular matrix Glycoprotein Golgi apparatus Growth factor Hydrolase Metal-binding Metalloprotease Methylation Osteogenesis Osteo... | MPGVARLPLL | MPGVARLPLLLGLLLLPRPGRPLDLADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDEEDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGRSRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCP... | cartilage condensation cell differentiation collagen fibril organization dorsal/ventral pattern formation ossification positive regulation of cartilage development protein processing proteolysis skeletal system development extracellular region; extracellular space; Golgi apparatus; vesicle calcium ion binding cytokine ... |
cytochrome complex assembly establishment of localization in cell hydrogen peroxide biosynthetic process inflammatory response innate immune response mucus secretion positive regulation of defense response to bacterium positive regulation of interleukin-6 production positive regulation of mucus secretion positive regul... | endoplasmic reticulum membrane; endosome; membrane; NADPH oxidase complex; phagocytic vesicle membrane; plasma membrane; secretory granule; specific granule membrane; tertiary granule membrane | electron transfer activity heme binding metal ion binding protein heterodimerization activity SH3 domain binding | Homo sapiens | 3D-structure Cell membrane Chronic granulomatous disease Direct protein sequencing Disease variant Electron transport Heme Iron Isopeptide bond Membrane Metal-binding NADP Oxidoreductase Phosphoprotein Reference proteome Transport Ubl conjugation | MGQIEWAMWA | MGQIEWAMWANEQALASGLILITGGIVATAGRFTQWYFGAYSIVAGVFVCLLEYPRGKRKKGSTMERWGQKYMTAVVKLFGPFTRNYYVRAVLHLLLSVPAGFLLATILGTACLAIASGIYLLAAVRGEQWTPIEPKPRERPQIGGTIKQPPSNPPPRPPAEARKKPSEEEAAVAAGGPPGGPQVNPIPVTDEVV | cytochrome complex assembly establishment of localization in cell hydrogen peroxide biosynthetic process inflammatory response innate immune response mucus secretion positive regulation of defense response to bacterium positive regulation of interleukin-6 production positive regulation of mucus secretion positive regul... |
cytokine-mediated signaling pathway heat acclimation inflammatory response interleukin-1-mediated signaling pathway positive regulation of interleukin-1-mediated signaling pathway positive regulation of neuron migration positive regulation of neutrophil extravasation positive regulation of T-helper 1 cell cytokine prod... | axon; cell surface; external side of plasma membrane; extracellular space; membrane; plasma membrane; protein-containing complex | interleukin-1 binding interleukin-1 receptor activity interleukin-1, type I, activating receptor activity ionotropic glutamate receptor binding NAD(P)+ nucleosidase activity NAD+ nucleotidase, cyclic ADP-ribose generating platelet-derived growth factor receptor binding protease binding | Mus musculus | Alternative promoter usage Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Immunoglobulin domain Inflammatory response Membrane NAD Phosphoprotein Receptor Reference proteome Repeat Secreted Signal Transmembrane Transmembrane helix | MENMKVLLGL | MENMKVLLGLICLMVPLLSLEIDVCTEYPNQIVLFLSVNEIDIRKCPLTPNKMHGDTIIWYKNDSKTPISADRDSRIHQQNEHLWFVPAKVEDSGYYYCIVRNSTYCLKTKVTVTVLENDPGLCYSTQATFPQRLHIAGDGSLVCPYVSYFKDENNELPEVQWYKNCKPLLLDNVSFFGVKDKLLVRNVAEEHRGDYICRMSYTFRGKQYPVTRVIQFITIDENKRDRPVILSPRNETIEADPGSMIQLICNVTGQFSDLVYWKWNGSEIEWNDPFLAEDYQFVEHPSTKRKYTLITTLNISEVKSQFYRYPFICVVKNT... | cytokine-mediated signaling pathway heat acclimation inflammatory response interleukin-1-mediated signaling pathway positive regulation of interleukin-1-mediated signaling pathway positive regulation of neuron migration positive regulation of neutrophil extravasation positive regulation of T-helper 1 cell cytokine prod... |
starch catabolic process | extracellular region | alpha-amylase activity glucan 1,4-alpha-maltotetraohydrolase activity metal ion binding starch binding | Stutzerimonas stutzeri | 3D-structure Calcium Carbohydrate metabolism Direct protein sequencing Disulfide bond Glycosidase Hydrolase Metal-binding Secreted Signal | MSHILRAAVL | MSHILRAAVLAAMLLPLPSMADQAGKSPNAVRYHGGDEIILQGFHWNVVREAPNDWYNILRQQAATIAADGFSAIWMPVPWRDFSSWSDGSKSGGGEGYFWHDFNKNGRYGSDAQLRQAASALGGAGVKVLYDVVPNHMNRGYPDKEINLPAGQGFWRNDCADPGNYPNDCDDGDRFIGGDADLNTGHPQVYGMFRDEFTNLRSQYGAGGFRFDFVRGYAPERVNSWMTDSADNSFCVGELWKGPSEYPNWDWRNTASWQQIIKDWSDRAKCPVFDFALKERMQNGSIADWKHGLNGNPDPRWREVAVTFVDNHDTGYSP... | starch catabolic process extracellular region alpha-amylase activity glucan 1,4-alpha-maltotetraohydrolase activity metal ion binding starch binding Stutzerimonas stutzeri 3D-structure Calcium Carbohydrate metabolism Direct protein sequencing Disulfide bond Glycosidase Hydrolase Metal-binding Secreted Signal MSHILRAAVL... |
detoxification of zinc ion response to cadmium ion zinc ion transport | plasma membrane | monoatomic cation transmembrane transporter activity | Cupriavidus metallidurans | 3D-structure Cadmium Cadmium resistance Cell inner membrane Cell membrane Cobalt Ion transport Membrane Plasmid Reference proteome Transmembrane Transmembrane helix Transport Zinc Zinc transport | MGAGHSHDHP | MGAGHSHDHPGGNERSLKIALALTGTFLIAEVVGGVMTKSLALISDAAHMLTDTVALAIALAAIAIAKRPADKKRTFGYYRFEILAAAFNALLLFGVAIYILYEAYLRLKSPPQIESTGMFVVAVLGLIINLISMRMLSSGQSSSLNVKGAYLEVWSDLLGSVGVIAGAIIIRFTGWAWVDSAIAVLIGLWVLPRTWILLKSSLNVLLEGVPDDVDLAEVEKQILATPGVKSFHDLHIWALTSGKASLTVHVVNDTAVNPEMEVLPELKQMLADKFDITHVTIQFELAPCEQADAAQHFNASPALVGSKSLAAGGN | detoxification of zinc ion response to cadmium ion zinc ion transport plasma membrane monoatomic cation transmembrane transporter activity Cupriavidus metallidurans 3D-structure Cadmium Cadmium resistance Cell inner membrane Cell membrane Cobalt Ion transport Membrane Plasmid Reference proteome Transmembrane Transmemb... |
brown fat cell differentiation cholesterol homeostasis defense response to Gram-positive bacterium fatty acid biosynthetic process lipid biosynthetic process lipid homeostasis monounsaturated fatty acid biosynthetic process positive regulation of cold-induced thermogenesis response to bacterium response to fatty acid r... | endoplasmic reticulum; endoplasmic reticulum membrane; membrane; nucleolus | iron ion binding metal ion binding oxidoreductase activity palmitoyl-CoA 9-desaturase activity stearoyl-CoA 9-desaturase activity | Mus musculus | 3D-structure Disease variant Endoplasmic reticulum Fatty acid biosynthesis Fatty acid metabolism Iron Lipid biosynthesis Lipid metabolism Membrane Metal-binding Microsome Oxidoreductase Reference proteome Transmembrane Transmembrane helix | MPAHMLQEIS | MPAHMLQEISSSYTTTTTITAPPSGNEREKVKTVPLHLEEDIRPEMKEDIHDPTYQDEEGPPPKLEYVWRNIILMVLLHLGGLYGIILVPSCKLYTCLFGIFYYMTSALGITAGAHRLWSHRTYKARLPLRIFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGGKLDMSDLKAEKLVMFQRRYYKPGLLLMCFILPTLVPWYCWGETFVNSLFVSTFLRYTLVLNATWLVNSAAHLYGYRPYDKNIQSRENILVSLGAVGEGFHNYHHTFPFDYSASEYRWHINFTTFFI... | brown fat cell differentiation cholesterol homeostasis defense response to Gram-positive bacterium fatty acid biosynthetic process lipid biosynthetic process lipid homeostasis monounsaturated fatty acid biosynthetic process positive regulation of cold-induced thermogenesis response to bacterium response to fatty acid r... |
actin cytoskeleton organization barbed-end actin filament capping cell morphogenesis filamentous growth | actin cortical patch; actin cytoskeleton; cellular bud tip; F-actin capping protein complex; incipient cellular bud site; mating projection tip; plasma membrane | actin filament binding | Saccharomyces cerevisiae | Acetylation Actin capping Actin-binding Cytoplasm Cytoskeleton Direct protein sequencing Phosphoprotein Reference proteome | MSDAQFDAAL | MSDAQFDAALDLLRRLNPTTLQENLNNLIELQPNLAQDLLSSVDVPLSTQKDSADSNREYLCCDYNRDIDSFRSPWSNTYYPELSPKDLQDSPFPSAPLRKLEILANDSFDVYRDLYYEGGISSVYLWDLNEEDFNGHDFAGVVLFKKNQSDHSNWDSIHVFEVTTSPSSPDSFNYRVTTTIILHLDKTKTDQNSHMMLSGNLTRQTEKDIAIDMSRPLDVIFTSHVANLGSLIEDIESQMRNLLETVYFEKTRDIFHQTKNAAIASSAEEANKDAQAEVIRGLQSL | actin cytoskeleton organization barbed-end actin filament capping cell morphogenesis filamentous growth actin cortical patch; actin cytoskeleton; cellular bud tip; F-actin capping protein complex; incipient cellular bud site; mating projection tip; plasma membrane actin filament binding Saccharomyces cerevisiae Acetyl... |
ncRNA catabolic process regulation of RNA metabolic process | plasma membrane; protein-containing complex | identical protein binding | Escherichia coli | Cell membrane Coiled coil Membrane Reference proteome Transmembrane Transmembrane helix | MRLTTKFSAF | MRLTTKFSAFVTLLTGLTIFVTLLGCSLSFYNAIQYKFSHRVQAVATAIDTHLVSNDFSVLRPQITELMMSADIVRVDLLHGDKQVYTLARNGSYRPVGSSDLFRELSVPLIKHPGMSLRLVYQDPMGNYFHSLMTTAPLTGAIGFIIVMLFLAVRWLQRQLAGQELLETRATRILNGERGSNVLGTIYEWPPRTSSALDTLLREIQNAREQHSRLDTLIRSYAAQDVKTGLNNRLFFDNQLATLLEDQEKVGTHGIVMMIRLPDFNMLSDTWGHSQVEEQFFTLTNLLSTFMMRYPGALLARYHRSDFAALLPHRTLKE... | ncRNA catabolic process regulation of RNA metabolic process plasma membrane; protein-containing complex identical protein binding Escherichia coli Cell membrane Coiled coil Membrane Reference proteome Transmembrane Transmembrane helix MRLTTKFSAF MRLTTKFSAFVTLLTGLTIFVTLLGCSLSFYNAIQYKFSHRVQAVATAIDTHLVSNDFSVLRPQITELMMSADI... |
angiogenesis endothelial cell migration eosinophil chemotaxis induction of positive chemotaxis inflammatory response intracellular signal transduction MAPK cascade negative regulation of endothelial cell apoptotic process negative regulation of endothelial cell proliferation negative regulation of extrinsic apoptotic s... | endoplasmic reticulum lumen; extracellular space; neuronal dense core vesicle; secretory granule | chemoattractant activity cytokine activity | Homo sapiens | Calcium Cleavage on pair of basic residues Glycoprotein Phosphoprotein Reference proteome Secreted Signal Sulfation | MAEAKTHWLG | MAEAKTHWLGAALSLIPLIFLISGAEAASFQRNQLLQKEPDLRLENVQKFPSPEMIRALEYIENLRQQAHKEESSPDYNPYQGVSVPLQQKENGDESHLPERDSLSEEDWMRIILEALRQAENEPQSAPKENKPYALNSEKNFPMDMSDDYETQQWPERKLKHMQFPPMYEENSRDNPFKRTNEIVEEQYTPQSLATLESVFQELGKLTGPNNQKRERMDEEQKLYTDDEDDIYKANNIAYEDVVGGEDWNPVEEKIESQTQEEVRDSKENIEKNEQINDEMKRSGQLGIQEEDLRKESKDQLSDDVSKVIAYLKRLVNA... | angiogenesis endothelial cell migration eosinophil chemotaxis induction of positive chemotaxis inflammatory response intracellular signal transduction MAPK cascade negative regulation of endothelial cell apoptotic process negative regulation of endothelial cell proliferation negative regulation of extrinsic apoptotic s... |
mechanosensory behavior neuron development neuron fate specification positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II response to mechanical stimulus sensory perception of smell | nucleus; RNA polymerase II transcription regulator complex | DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II-specific DNA-binding transcription factor binding sequence-specific DNA binding | Caenorhabditis elegans | Alternative splicing DNA-binding Homeobox Neurogenesis Nucleus Olfaction Reference proteome Sensory transduction Transcription Transcription regulation | MQNTAPVPTT | MQNTAPVPTTTTASKMQPFNNSLFGSFDDPILNARAAQVALADIDVKNVPQLTNPLMRPHDMFSYSNYFSGIHDTSAATNIYQGLPSSSEPFDASVVVPTSSDDQMTPLQQVMAMQQSYGAPPPFQYNMTHPFSTTSIASSNNLARYPIAPPTSDMDTDPRQLETFAEHFKQRRIKLGVTQADVGKALAHLKMPGVGSLSQSTICRFESLTLSHNNMVALKPILHSWLEKAEEAMKQKDTIGDINGILPNTDKKRKRTSIAAPEKRELEQFFKQQPRPSGERIASIADRLDLKKNVVRVWFCNQRQKQKRDFRSQFRARS... | mechanosensory behavior neuron development neuron fate specification positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II response to mechanical stimulus sensory perception of smell nucleus; RNA polymerase II transcription regulator complex DNA-binding transcription... |
male sex determination negative regulation of apoptotic process negative regulation of immature T cell proliferation negative regulation of neuron migration regulation of gene expression regulation of ovarian follicle development reproduction response to ethanol response to steroid hormone | axon terminus; cytoplasmic side of rough endoplasmic reticulum membrane; dendrite; extracellular space; Golgi-associated vesicle; neurosecretory vesicle; perikaryon | gonadotropin hormone-releasing hormone activity gonadotropin-releasing hormone receptor binding | Mus musculus | Amidation Cleavage on pair of basic residues Hormone Pyrrolidone carboxylic acid Reference proteome Secreted Signal | MILKLMAGIL | MILKLMAGILLLTVCLEGCSSQHWSYGLRPGGKRNTEHLVESFQEMGKEVDQMAEPQHFECTVHWPRSPLRDLRGALESLIEEEARQKKM | male sex determination negative regulation of apoptotic process negative regulation of immature T cell proliferation negative regulation of neuron migration regulation of gene expression regulation of ovarian follicle development reproduction response to ethanol response to steroid hormone axon terminus; cytoplasmic si... |
conjugation with cellular fusion invasive growth in response to glucose limitation negative regulation of mating-type specific transcription, DNA-templated negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II pseudohyphal growth regulation of filamentous gr... | nucleoplasm; nucleus; Ste12p-Dig1p-Dig2p complex; Tec1p-Ste12p-Dig1p complex | DNA binding DNA-binding transcription factor activity | Saccharomyces cerevisiae | 3D-structure Activator DNA-binding Nucleus Pheromone response Phosphoprotein Reference proteome Transcription Transcription regulation | MKVQITNSRT | MKVQITNSRTEEILKVQANNENDEVSKATPGEVEESLRLIGDLKFFLATAPVNWQENQIIRRYYLNSGQGFVSCVFWNNLYYITGTDIVKCCLYRMQKFGREVVQKKKFEEGIFSDLRNLKCGIDATLEQPKSEFLSFLFRNMCLKTQKKQKVFFWFSVAHDKLFADALERDLKRESLNQPSTTKPVNEPALSFSYDSSSDKPLYDQLLQHLDSRRPSSTTKSDNSPPKLESENFKDNELVTVTNQPLLGVGLMDDDAPESPSQINDFIPQKLIIEPNTLELNGLTEETPHDLPKNTAKGRDEEDFPLDYFPVSVEYPTE... | conjugation with cellular fusion invasive growth in response to glucose limitation negative regulation of mating-type specific transcription, DNA-templated negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II pseudohyphal growth regulation of filamentous gr... |
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