Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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dorsal/ventral axis specification dorsal/ventral pattern formation maternal specification of dorsal/ventral axis, oocyte, germ-line encoded proteolysis Toll receptor ligand protein activation cascade ventral furrow formation | extracellular region; extracellular space; perivitelline space | metal ion binding serine-type endopeptidase activity | Drosophila melanogaster | Calcium Developmental protein Disulfide bond Hydrolase Metal-binding Protease Reference proteome Secreted Serine protease Signal Zymogen | MLKPSIICLF | MLKPSIICLFLGILAKSSAGQFYFPNEAAQVPNYGRCITPNRERALCIHLEDCKYLYGLLTTTPLRDTDRLYLSRSQCGYTNGKVLICCPDRYRESSSETTPPPKPNVTSNSLLPLPGQCGNILSNRIYGGMKTKIDEFPWMALIEYTKSQGKKGHHCGGSLISTRYVITASHCVNGKALPTDWRLSGVRLGEWDTNTNPDCEVDVRGMKDCAPPHLDVPVERTIPHPDYIPASKNQVNDIALLRLAQQVEYTDFVRPICLPLDVNLRSATFDGITMDVAGWGKTEQLSASNLKLKAAVEGSRMDECQNVYSSQDILLED... | dorsal/ventral axis specification dorsal/ventral pattern formation maternal specification of dorsal/ventral axis, oocyte, germ-line encoded proteolysis Toll receptor ligand protein activation cascade ventral furrow formation extracellular region; extracellular space; perivitelline space metal ion binding serine-type en... |
biphenyl metabolic process fatty acid metabolic process | endoplasmic reticulum membrane | aromatase activity heme binding heterocyclic compound binding iron ion binding monooxygenase activity oxygen binding | Homo sapiens | Alternative splicing Endoplasmic reticulum Heme Iron Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Phosphoprotein Reference proteome | MVPSFLSLSF | MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALEIQETGSLDKVVSWAHQFPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTT... | biphenyl metabolic process fatty acid metabolic process endoplasmic reticulum membrane aromatase activity heme binding heterocyclic compound binding iron ion binding monooxygenase activity oxygen binding Homo sapiens Alternative splicing Endoplasmic reticulum Heme Iron Membrane Metal-binding Microsome Monooxygenase Oxi... |
calcium ion import into sarcoplasmic reticulum calcium ion transmembrane transport calcium ion transport intracellular calcium ion homeostasis negative regulation of striated muscle contraction positive regulation of fast-twitch skeletal muscle fiber contraction regulation of striated muscle contraction | endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment; H zone; I band; membrane; perinuclear region of cytoplasm; sarcoplasmic reticulum; sarcoplasmic reticulum membrane | ATP binding ATP hydrolysis activity calcium ion binding P-type calcium transporter activity | Gallus gallus | ATP-binding Calcium Calcium transport Disulfide bond Endoplasmic reticulum Ion transport Magnesium Membrane Metal-binding Nucleotide-binding Phosphoprotein Reference proteome Sarcoplasmic reticulum Translocase Transmembrane Transmembrane helix Transport | MENAHAKTAE | MENAHAKTAEECLAFFGVNESVGLSGEQVRRALEKYGHNELPAEEGKTIWELVVEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAVVGVWQERNAENAIEALKEYEPEMGKVYRADRKAVQRIKARDLVPGDIAEVAVGDKVPADIRIISIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIGAGKAVGIVVATGVNTEIGKIRDEMAATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLA... | calcium ion import into sarcoplasmic reticulum calcium ion transmembrane transport calcium ion transport intracellular calcium ion homeostasis negative regulation of striated muscle contraction positive regulation of fast-twitch skeletal muscle fiber contraction regulation of striated muscle contraction endoplasmic ret... |
calcium ion transmembrane transport calcium ion transport intracellular calcium ion homeostasis intracellular manganese ion homeostasis macroautophagy manganese ion transport | endoplasmic reticulum; Golgi apparatus; Golgi membrane; plasma membrane | ATP binding ATP hydrolysis activity calcium ion binding P-type calcium transporter activity P-type manganese transporter activity | Saccharomyces cerevisiae | Acetylation ATP-binding Calcium Calcium transport Golgi apparatus Ion transport Magnesium Membrane Nucleotide-binding Phosphoprotein Reference proteome Translocase Transmembrane Transmembrane helix Transport | MSDNPFNASL | MSDNPFNASLLDEDSNREREILDATAEALSKPSPSLEYCTLSVDEALEKLDTDKNGGLRSSNEANNRRSLYGPNEITVEDDESLFKKFLSNFIEDRMILLLIGSAVVSLFMGNIDDAVSITLAIFIVVTVGFVQEYRSEKSLEALNKLVPAECHLMRCGQESHVLASTLVPGDLVHFRIGDRIPADIRIIEAIDLSIDESNLTGENEPVHKTSQTIEKSSFNDQPNSIVPISERSCIAYMGTLVKEGHGKGIVVGTGTNTSFGAVFEMMNNIEKPKTPLQLTMDKLGKDLSLVSFIVIGMICLVGIIQGRSWLEMFQISV... | calcium ion transmembrane transport calcium ion transport intracellular calcium ion homeostasis intracellular manganese ion homeostasis macroautophagy manganese ion transport endoplasmic reticulum; Golgi apparatus; Golgi membrane; plasma membrane ATP binding ATP hydrolysis activity calcium ion binding P-type calcium tr... |
cell adhesion commissural neuron axon guidance epithelial to mesenchymal transition regulation of semaphorin-plexin signaling pathway | cell surface; collagen-containing extracellular matrix; cytosol; external side of plasma membrane; extracellular region; Golgi membrane; membrane; plasma membrane | virus receptor activity | Homo sapiens | 3D-structure Alternative splicing Cell adhesion Cell membrane Disulfide bond Glycoprotein GPI-anchor Host cell receptor for virus entry Host-virus interaction Immunoglobulin domain Lipoprotein Membrane Phosphoprotein Receptor Reference proteome Repeat Secreted Signal Transmembrane Transmembrane helix | MLQTKDLIWT | MLQTKDLIWTLFFLGTAVSLQVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAME... | cell adhesion commissural neuron axon guidance epithelial to mesenchymal transition regulation of semaphorin-plexin signaling pathway cell surface; collagen-containing extracellular matrix; cytosol; external side of plasma membrane; extracellular region; Golgi membrane; membrane; plasma membrane virus receptor activity... |
animal organ regeneration axonal fasciculation calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules calcium-mediated signaling cell adhesion cell surface receptor signaling pathway cellular response to inorganic substance cellular response to molecule of bacterial origin commissural neuron... | axon; cell surface; cell-cell junction; external side of plasma membrane; glutamatergic synapse; growth cone; neuronal cell body; plasma membrane; postsynaptic membrane; presynaptic membrane; Schaffer collateral - CA1 synapse | cytoskeletal protein binding fibroblast growth factor receptor binding heparin binding LRR domain binding phosphatase binding | Rattus norvegicus | 3D-structure Alternative splicing Cell adhesion Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Heparin-binding Immunoglobulin domain Membrane Phosphoprotein Reference proteome Repeat Signal Transmembrane Transmembrane helix | MLRTKDLIWT | MLRTKDLIWTLFFLGTAVSLQVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLSPNQQRISVVWNDDDSSTLTIYNANIDDAGIYKCVVTAEDGTQSEATVNVKIFQKLMFKNAPTPQEFKEGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTVQARQSIVNATANLGQSVTLVCDADGFPEPTMSWTKDGEPIENEEEDDEKHIFSDDSSELTIRNVDKNDEAEYVCIAENKAGEQDASIHLKVFAKPKITYVENQTAM... | animal organ regeneration axonal fasciculation calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules calcium-mediated signaling cell adhesion cell surface receptor signaling pathway cellular response to inorganic substance cellular response to molecule of bacterial origin commissural neuron... |
cell adhesion cell-cell adhesion | cleavage furrow; membrane; microvillus; plasma membrane; uropod | integrin binding | Homo sapiens | 3D-structure Cell adhesion Cell projection Direct protein sequencing Disulfide bond Glycoprotein Immunoglobulin domain Membrane Reference proteome Repeat Signal Transmembrane Transmembrane helix | MSSFGYRTLT | MSSFGYRTLTVALFTLICCPGSDEKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKILLDEQAQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQPTLVAVGKSFTIECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGHRNFSCLAVLDLMSRGGNIFHKHSAPKMLEIYEPVSDSQMVIIVTVVSVLLSLFVTSVLLCFIFGQHLRQQRMGTYGVRAAWRRLPQAFRP | cell adhesion cell-cell adhesion cleavage furrow; membrane; microvillus; plasma membrane; uropod integrin binding Homo sapiens 3D-structure Cell adhesion Cell projection Direct protein sequencing Disulfide bond Glycoprotein Immunoglobulin domain Membrane Reference proteome Repeat Signal Transmembrane Transmembrane heli... |
humoral immune response immune response | endosome membrane; external side of plasma membrane; extracellular space | beta-2-microglobulin binding IgG binding IgG receptor activity | Rattus norvegicus | 3D-structure Cell membrane Direct protein sequencing Disulfide bond Endosome Glycoprotein IgG-binding protein Immunoglobulin domain Membrane Phosphoprotein Receptor Reference proteome Signal Transmembrane Transmembrane helix | MGMSQPGVLL | MGMSQPGVLLSLLLVLLPQTWGAEPRLPLMYHLAAVSDLSTGLPSFWATGWLGAQQYLTYNNLRQEADPCGAWIWENQVSWYWEKETTDLKSKEQLFLEAIRTLENQINGTFTLQGLLGCELAPDNSSLPTAVFALNGEEFMRFNPRTGNWSGEWPETDIVGNLWMKQPEAARKESEFLLTSCPERLLGHLERGRQNLEWKEPPSMRLKARPGNSGSSVLTCAAFSFYPPELKFRFLRNGLASGSGNCSTGPNGDGSFHAWSLLEVKRGDEHHYQCQVEHEGLAQPLTVDLDSPARSSVPVVGIILGLLLVVVAIAGGVL... | humoral immune response immune response endosome membrane; external side of plasma membrane; extracellular space beta-2-microglobulin binding IgG binding IgG receptor activity Rattus norvegicus 3D-structure Cell membrane Direct protein sequencing Disulfide bond Endosome Glycoprotein IgG-binding protein Immunoglobulin d... |
ethanol catabolic process operant conditioning | cytoplasm | 3-chloroallyl aldehyde dehydrogenase activity aldehyde dehydrogenase (NAD+) activity benzaldehyde dehydrogenase (NAD+) activity glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity identical protein binding NAD binding | Rattus norvegicus | Acetylation Cytoplasm NAD Oxidoreductase Phosphoprotein Reference proteome | MSSPAQPAVP | MSSPAQPAVPAPLANLKIQHTKIFINNEWHNSLNGKKFPVINPATEEVICHVEEGDKADVDKAVKAARQAFQIGSPWRTMDASERGCLLNKLADLMERDRVLLATMESMNAGKIFTHAYLLDTEVSIKALKYFAGWADKIHGQTIPSDGDVFTYTRREPIGVCGQIIPWNGPLILFIWKIGAALSCGNTVIVKPAEQTPLTALYMASLIKEAGFPPGVVNVVPGYGSTAGAAISSHMDIDKVSFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVFADADLDSAVEFAHQGVFFHQGQICVAASRLFVEESIYDEFV... | ethanol catabolic process operant conditioning cytoplasm 3-chloroallyl aldehyde dehydrogenase activity aldehyde dehydrogenase (NAD+) activity benzaldehyde dehydrogenase (NAD+) activity glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity identical protein binding NAD binding Rattus norvegicus ... |
apoptotic process biomineral tissue development granzyme-mediated programmed cell death signaling pathway maintenance of granzyme B location in T cell secretory granule maintenance of protease location in mast cell secretory granule mast cell secretory granule organization modulation of chemical synaptic transmission n... | cytolytic granule; extracellular space; glutamatergic synapse; Golgi apparatus; mast cell granule; postsynaptic specialization, intracellular component; Schaffer collateral - CA1 synapse; secretory granule; zymogen granule | collagen binding | Mus musculus | Apoptosis Biomineralization Direct protein sequencing Disulfide bond Glycoprotein Golgi apparatus Lysosome Proteoglycan Reference proteome Repeat Secreted Signal | MQVPVGSRLV | MQVPVGSRLVLALAFVLVWGSSVQGYPARRARYQWVRCKPNGFFANCIEEKGPQFDLIDESNNIGPPMNNPVLMEGPSKDFISNYDDYGSGSGSGSGSGSGSGSGSGSGFLGDMEWEYQPTDESNIVYFNYKPFDRILTEQNQDQPEDDFII | apoptotic process biomineral tissue development granzyme-mediated programmed cell death signaling pathway maintenance of granzyme B location in T cell secretory granule maintenance of protease location in mast cell secretory granule mast cell secretory granule organization modulation of chemical synaptic transmission n... |
anterior commissure morphogenesis chondrocyte differentiation club cell differentiation commissural neuron axon guidance DNA replication glial cell differentiation lung ciliated cell differentiation negative regulation of epithelial cell proliferation involved in lung morphogenesis negative regulation of mesenchymal ce... | cerebellar mossy fiber; nucleus | DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific | Mesocricetus auratus | Activator Alternative splicing DNA replication DNA-binding Methylation Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MMYSPICLTQ | MMYSPICLTQDEFHPFIEALLPHVRAIAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLSEKPEIKQKWASRLLAKLRKDIRQEYREDFVLTVTGKKHPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLMKSPHCTNPALCVQPHHITVSVKELDLFLAYYVQEQDSGQSGSPSHNDPAKNPPGYLEDSFVKSGVFNVSELVRVSRTPITQGTGVNFPIGEIPSQPYYHDMNSGVNLQRSLSSPPSSKRPKTISIDENMEPSPTGDFYPSPNSPAAGSRTWHERDQDMSSPTTMKKPE... | anterior commissure morphogenesis chondrocyte differentiation club cell differentiation commissural neuron axon guidance DNA replication glial cell differentiation lung ciliated cell differentiation negative regulation of epithelial cell proliferation involved in lung morphogenesis negative regulation of mesenchymal ce... |
cell communication by electrical coupling involved in cardiac conduction cellular response to amyloid-beta cellular response to steroid hormone stimulus intracellular potassium ion homeostasis intracellular sodium ion homeostasis neuron projection maintenance potassium ion import across plasma membrane proton transmemb... | axon; endoplasmic reticulum; extracellular vesicle; Golgi apparatus; membrane; neuron to neuron synapse; neuronal cell body; neuronal cell body membrane; organelle membrane; photoreceptor inner segment; photoreceptor inner segment membrane; plasma membrane; sodium:potassium-exchanging ATPase complex; synapse | amyloid-beta binding ATP binding ATP hydrolysis activity metal ion binding P-type sodium:potassium-exchanging transporter activity protein-folding chaperone binding steroid hormone binding | Homo sapiens | 3D-structure Alternative splicing ATP-binding Cell membrane Deafness Disease variant Dystonia Epilepsy Intellectual disability Ion transport Magnesium Membrane Metal-binding Nucleotide-binding Parkinsonism Phosphoprotein Potassium Potassium transport Reference proteome Sodium Sodium transport Sodium/potassium transport... | MGDKKDDKDS | MGDKKDDKDSPKKNKGKERRDLDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSLILGYTWLEAVIFLIGIIVA... | cell communication by electrical coupling involved in cardiac conduction cellular response to amyloid-beta cellular response to steroid hormone stimulus intracellular potassium ion homeostasis intracellular sodium ion homeostasis neuron projection maintenance potassium ion import across plasma membrane proton transmemb... |
cell-substrate adhesion intracellular potassium ion homeostasis intracellular sodium ion homeostasis lateral ventricle development membrane repolarization motor behavior negative regulation of glial cell migration neuronal-glial interaction involved in hindbrain glial-mediated radial cell migration photoreceptor cell m... | apical plasma membrane; astrocyte end-foot; astrocyte projection; cell body membrane; cell periphery; cell projection membrane; cytoplasm; external side of plasma membrane; lateral plasma membrane; membrane; neuron to neuron synapse; photoreceptor inner segment; plasma membrane; sodium:potassium-exchanging ATPase compl... | ATPase activator activity ATPase binding P-type sodium:potassium-exchanging transporter activity protein heterodimerization activity protein-macromolecule adaptor activity | Rattus norvegicus | Cell adhesion Cell membrane Disulfide bond Glycoprotein Ion transport Membrane Potassium Potassium transport Reference proteome Signal-anchor Sodium Sodium transport Sodium/potassium transport Transmembrane Transmembrane helix Transport | MVIQKEKKSC | MVIQKEKKSCGQVVEEWKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFTLTMWVMLQTVSDHTPKYQDRLATPGLMIRPKTENLDVIVNISDTESWDQHVQKLNKFLEPYNDSIQAQKNDVCRPGRYYEQPDNGVLNYPKRACQFNRTQLGNCSGIGDPTHYGYSTGQPCVFIKMNRVINFYAGANQSMNVTCVGKKDEDAENLGHFIMFPANGNIDLMYFPYYGKKFHVNYTQPLVAVKFLNVTPNVEVNVECRINAANIATDDERDKFAARVAFKLRINKA | cell-substrate adhesion intracellular potassium ion homeostasis intracellular sodium ion homeostasis lateral ventricle development membrane repolarization motor behavior negative regulation of glial cell migration neuronal-glial interaction involved in hindbrain glial-mediated radial cell migration photoreceptor cell m... |
hematopoietic progenitor cell differentiation positive regulation of translation translational elongation | aggresome; cytoplasm; cytosol; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; membrane; nucleus; plasma membrane; ribonucleoprotein complex; ribosome; secretory granule lumen; synapse | cadherin binding GTP binding GTPase activity protein kinase binding ribosome binding RNA binding translation elongation factor activity | Homo sapiens | 3D-structure Acetylation ADP-ribosylation Cytoplasm Direct protein sequencing Disease variant Elongation factor GTP-binding Hydrolase Isopeptide bond Methylation Neurodegeneration Nucleotide-binding Nucleus Phosphoprotein Protein biosynthesis Reference proteome Spinocerebellar ataxia Ubl conjugation | MVNFTVDQIR | MVNFTVDQIRAIMDKKANIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQERCITIKSTAISLFYELSENDLNFIKQSKDGAGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEGESGPMGNIMIDPVLGTVGFGSGLHGWAFTLKQFAEMYVAKFAAKGEGQLGPAERAKKVEDMMKKLWGDRYFDPANGKFSKSATSPEGKKLPRTFCQLILDPIFKVFDAIMNFKKEETAKLIEKLD... | hematopoietic progenitor cell differentiation positive regulation of translation translational elongation aggresome; cytoplasm; cytosol; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; membrane; nucleus; plasma membrane; ribonucleoprotein complex; ribosome; secretory granule lumen; synapse ca... |
cellular response to cadmium ion cellular response to copper ion cellular response to vascular endothelial growth factor stimulus cellular response to zinc ion detoxification of copper ion intracellular zinc ion homeostasis monocyte activation monocyte differentiation negative regulation of growth | cytoplasm; nucleus | metal ion binding zinc ion binding | Homo sapiens | Acetylation Alternative splicing Cadmium Copper Direct protein sequencing Metal-binding Metal-thiolate cluster Phosphoprotein Reference proteome Zinc | MDPNCSCAAA | MDPNCSCAAAGVSCTCASSCKCKECKCTSCKKSCCSCCPVGCAKCAQGCICKGASEKCSCCA | cellular response to cadmium ion cellular response to copper ion cellular response to vascular endothelial growth factor stimulus cellular response to zinc ion detoxification of copper ion intracellular zinc ion homeostasis monocyte activation monocyte differentiation negative regulation of growth cytoplasm; nucleus me... |
cytoplasmic translation negative regulation of angiogenesis negative regulation of transcription by RNA polymerase II negative regulation of vascular endothelial growth factor production selenocysteine incorporation seryl-tRNA aminoacylation | cytoplasm; cytosol; nucleus | ATP binding RNA polymerase II cis-regulatory region sequence-specific DNA binding selenocysteine-tRNA ligase activity serine-tRNA ligase activity | Oryctolagus cuniculus | Acetylation Aminoacyl-tRNA synthetase ATP-binding Cytoplasm Direct protein sequencing DNA-binding Ligase Nucleotide-binding Nucleus Phosphoprotein Protein biosynthesis Reference proteome | MVLDLDLFRV | MVLDLDLFRVDKGGDPALIRETQEKRFKDPGLVDQLVKADSEWRRCRFRADNLNKLKNLCSKTIGEKMKKKEPVGDDESIPENVLNFDDVTADTLTNLKVSQIKKVRLLIDEAILKCDAERIKLEAERFESLREIGNLLHPSVPISNDEDADNKVERIWGDCTVRKKYSHVDLVVMVDGFEGEKGAVVAGSRGYFLKGVLVFLEQALIQYALRTLRNRGYTPIYTPFFMRKEVMQEVAQLSQFDEELYKVIGKGSEKSDDNSYDEKYLIATSEQPIAALHRDEWLRPEDLPIKYAGLSTCFRQEVGSHGRDTRGIFRVHQ... | cytoplasmic translation negative regulation of angiogenesis negative regulation of transcription by RNA polymerase II negative regulation of vascular endothelial growth factor production selenocysteine incorporation seryl-tRNA aminoacylation cytoplasm; cytosol; nucleus ATP binding RNA polymerase II cis-regulatory regio... |
epidermis development epithelial cell differentiation intermediate filament organization keratinocyte differentiation peptide cross-linking positive regulation of epidermis development protein heterotetramerization | cell surface; cornified envelope; cytoplasm; cytoskeleton; cytosol; extracellular exosome; extracellular space; intermediate filament; keratin filament; membrane; nucleus | protein heterodimerization activity structural constituent of skin epidermis | Homo sapiens | 3D-structure Coiled coil Cytoplasm Direct protein sequencing Disease variant Disulfide bond Ichthyosis Intermediate filament Keratin Phosphoprotein Reference proteome Secreted | MSVRYSSSKH | MSVRYSSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGIFGGGSFGGGSFGGGSFGGGGFGGGGFGGGFGGGFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSHQGEPRDYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEMNAAPGVDLTQLLNN... | epidermis development epithelial cell differentiation intermediate filament organization keratinocyte differentiation peptide cross-linking positive regulation of epidermis development protein heterotetramerization cell surface; cornified envelope; cytoplasm; cytoskeleton; cytosol; extracellular exosome; extracellular ... |
cytoskeleton organization epithelial cell differentiation intermediate filament organization regulation of translation in response to stress | cytoskeleton; cytosol; extracellular exosome; intermediate filament cytoskeleton; keratin filament; nucleus | structural molecule activity | Homo sapiens | Alternative splicing Coiled coil Direct protein sequencing Disease variant Glycoprotein Intermediate filament Keratin Methylation Phosphoprotein Reference proteome | MSLRLQSSSA | MSLRLQSSSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHTKSAELNKEVSTNTAMIQTSKTE... | cytoskeleton organization epithelial cell differentiation intermediate filament organization regulation of translation in response to stress cytoskeleton; cytosol; extracellular exosome; intermediate filament cytoskeleton; keratin filament; nucleus structural molecule activity Homo sapiens Alternative splicing Coiled c... |
epidermis development intermediate filament organization intermediate filament polymerization keratinization regulation of cell migration regulation of protein localization response to mechanical stimulus | cytoplasm; cytosol; extracellular exosome; intermediate filament; keratin filament; membrane; nucleus | scaffold protein binding structural constituent of cytoskeleton structural constituent of skin epidermis | Homo sapiens | 3D-structure Coiled coil Cytoplasm Disease variant Epidermolysis bullosa Intermediate filament Keratin Phosphoprotein Reference proteome | MSRQSSVSFR | MSRQSSVSFRSGGSRSFSTASAITPSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGYGSRSLYNLGGSKRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGGGAGFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDEINFMKMFFDAELSQMQTHVSD... | epidermis development intermediate filament organization intermediate filament polymerization keratinization regulation of cell migration regulation of protein localization response to mechanical stimulus cytoplasm; cytosol; extracellular exosome; intermediate filament; keratin filament; membrane; nucleus scaffold prot... |
chitin catabolic process polysaccharide catabolic process | extracellular region; outer membrane-bounded periplasmic space | carbohydrate binding chitin binding endochitinase activity lysozyme activity | Escherichia coli | Carbohydrate metabolism Chitin degradation Chitin-binding Disulfide bond Glycosidase Hydrolase Multifunctional enzyme Periplasm Polysaccharide degradation Reference proteome Repeat Signal | MKLNIFTKSM | MKLNIFTKSMIGMGLVCSALPALAMEAWNNQQGGNKYQVIFDGKIYENAWWVSSTNCPGKAKANDATNPWRLKRTATAAEISQFGNTLSCEKSGSSSSSNSNTPASNTPANGGSATPAQGTVPSNSSVVAWNKQQGGQTWYVVFNGAVYKNAWWVASSNCPGDAKSNDASNPWRYVRAATATEISETSNPQSCTSAPQPSPDVKPAPDVKPAPDVQPAPADKSNDNYAVVAWKGQEGSSTWYVIYNGGIYKNAWWVGAANCPGDAKENDASNPWRYVRAATATEISQYGNPGSCSVKPDNNGGAVTPVDPTPETPVTPTP... | chitin catabolic process polysaccharide catabolic process extracellular region; outer membrane-bounded periplasmic space carbohydrate binding chitin binding endochitinase activity lysozyme activity Escherichia coli Carbohydrate metabolism Chitin degradation Chitin-binding Disulfide bond Glycosidase Hydrolase Multifunct... |
homoserine biosynthetic process isoleucine biosynthetic process lysine biosynthetic process via diaminopimelate methionine biosynthetic process threonine biosynthetic process | cytoplasm; nucleus; plasma membrane | aspartate-semialdehyde dehydrogenase activity NAD binding NADP binding protein dimerization activity | Saccharomyces cerevisiae | Amino-acid biosynthesis Lysine biosynthesis Methionine biosynthesis NADP Oxidoreductase Phosphoprotein Reference proteome Threonine biosynthesis | MAGKKIAGVL | MAGKKIAGVLGATGSVGQRFILLLANHPHFELKVLGASSRSAGKKYVDAVNWKQTDLLPESATDIIVSECKSEFFKECDIVFSGLDADYAGAIEKEFMEAGIAIVSNAKNYRREQDVPLIVPVVNPEHLDIVAQKLDTAKAQGKPRPGFIICISNCSTAGLVAPLKPLIEKFGPIDALTTTTLQAISGAGFSPGVPGIDILDNIIPYIGGEEDKMEWETKKILAPLAEDKTHVKLLTPEEIKVSAQCNRVAVSDGHTECISLRFKNRPAPSVEQVKTCLKEYVCDAYKLGCHSAPKQTIHVLEQPDRPQPRLDRNRDSGY... | homoserine biosynthetic process isoleucine biosynthetic process lysine biosynthetic process via diaminopimelate methionine biosynthetic process threonine biosynthetic process cytoplasm; nucleus; plasma membrane aspartate-semialdehyde dehydrogenase activity NAD binding NADP binding protein dimerization activity Saccharo... |
chaperone-mediated protein folding protein folding protein secretion response to endoplasmic reticulum stress | cell surface; endoplasmic reticulum; endoplasmic reticulum lumen; extracellular space; melanosome | protein disulfide isomerase activity protein-disulfide reductase activity RNA binding | Homo sapiens | 3D-structure Acetylation Direct protein sequencing Disulfide bond Endoplasmic reticulum Isomerase Redox-active center Reference proteome Repeat Signal | MRPRKAFLLL | MRPRKAFLLLLLLGLVQLLAVAGAEGPDEDSSNRENAIEDEEEEEEEDDDEEEDDLEVKEENGVLVLNDANFDNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSASVLASRFDVSGYPTIKILKKGQAVDYEGSRTQEEIVAKVREVSQPDWTPPPEVTLVLTKENFDEVVNDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFDVSGYPTLKIFRKGRPYDYNGPREKYGIVDYMIEQSGPPSKEILTLKQVQEFLKDGDDVIIIGVFKGESDPAY... | chaperone-mediated protein folding protein folding protein secretion response to endoplasmic reticulum stress cell surface; endoplasmic reticulum; endoplasmic reticulum lumen; extracellular space; melanosome protein disulfide isomerase activity protein-disulfide reductase activity RNA binding Homo sapiens 3D-structure ... |
axonogenesis establishment of skin barrier hepatocyte growth factor receptor signaling pathway intracellular signal transduction microtubule depolymerization mitotic cytokinesis mitotic spindle organization negative regulation of microtubule polymerization negative regulation of Rho protein signal transduction negative... | cytoplasm; cytosol; membrane; microtubule; neuron projection | tubulin binding | Rattus norvegicus | Acetylation Coiled coil Cytoplasm Cytoskeleton Developmental protein Differentiation Direct protein sequencing Methylation Microtubule Neurogenesis Phosphoprotein Reference proteome | MASSDIQVKE | MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHVEEVRKNKESKDPADETEAD | axonogenesis establishment of skin barrier hepatocyte growth factor receptor signaling pathway intracellular signal transduction microtubule depolymerization mitotic cytokinesis mitotic spindle organization negative regulation of microtubule polymerization negative regulation of Rho protein signal transduction negative... |
collagen fibril organization | endoplasmic reticulum; endoplasmic reticulum lumen; intracellular membrane-bounded organelle; membrane; mitochondrion; procollagen-proline 4-dioxygenase complex | identical protein binding iron ion binding L-ascorbic acid binding procollagen-proline 4-dioxygenase activity | Homo sapiens | 3D-structure Alternative splicing Dioxygenase Endoplasmic reticulum Glycoprotein Iron Metal-binding Oxidoreductase Reference proteome Signal TPR repeat Vitamin C | MIWYILIIGI | MIWYILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGFISNLTIQRQYFPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADYYHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQRANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGVAVDYLPERQKYEMLCRGEGIKMTPRRQKKLFCRYHDGNRNPK... | collagen fibril organization endoplasmic reticulum; endoplasmic reticulum lumen; intracellular membrane-bounded organelle; membrane; mitochondrion; procollagen-proline 4-dioxygenase complex identical protein binding iron ion binding L-ascorbic acid binding procollagen-proline 4-dioxygenase activity Homo sapiens 3D-stru... |
adaptation of rhodopsin mediated signaling calcium-mediated signaling cell migration deactivation of rhodopsin mediated signaling detection of light stimulus involved in sensory perception female gonad development intracellular signal transduction phospholipase C-inhibiting G protein-coupled receptor signaling pathway ... | inaD signaling complex; rhabdomere | ATP binding diacylglycerol-dependent serine/threonine kinase activity protein serine kinase activity protein serine/threonine kinase activity zinc ion binding | Drosophila melanogaster | ATP-binding Calcium Kinase Metal-binding Nucleotide-binding Phosphoprotein Reference proteome Repeat Sensory transduction Serine/threonine-protein kinase Transferase Vision Zinc Zinc-finger | MAAAAVATPG | MAAAAVATPGATVLPPSVPSAAPGAKAPAAGAGKGPGNLLEITGEANIVNYMKNRLRKGAMKRKGLEMVNGHRFGVRFFKNPTYCGHCKDFIWGFGKQGFQCEECRFNIHQKCCKFVVFKCPGKDTDFDADCAKVKHGWISTTYTTPTFCDECGLLLHGVAHQGVKCENCNLNVHHACQETVPPMCGADISEVRGKLLLYVELKGNNLKVDIKEAANLIPMDTNGFSDPYIAVQMHPDRSGRTKKKTKTIQKNLNPVFNETFTFELQPQDRDKRLLIEVWDWDRTSRNDFMGSFSFSLEELQKEPVDGWYKFLSQVEGEH... | adaptation of rhodopsin mediated signaling calcium-mediated signaling cell migration deactivation of rhodopsin mediated signaling detection of light stimulus involved in sensory perception female gonad development intracellular signal transduction phospholipase C-inhibiting G protein-coupled receptor signaling pathway ... |
dorsal/ventral axis specification Golgi organization intracellular signal transduction lipid droplet organization long-term memory negative regulation of cell population proliferation protein phosphorylation response to ethanol | plasma membrane | ATP binding diacylglycerol-dependent serine/threonine kinase activity metal ion binding protein serine kinase activity protein serine/threonine kinase activity | Drosophila melanogaster | ATP-binding Calcium Kinase Metal-binding Nucleotide-binding Phosphoprotein Reference proteome Repeat Serine/threonine-protein kinase Transferase Zinc Zinc-finger | MFTGKLQIKV | MFTGKLQIKVCEASGLRPTDFQKRHNLTFGKLADEQLIDPYVSIDVDESHFDRATTRPKTFDPVWNEQFVHDVTNVSNINLTVFHDAALPPDDFVANCIISFEDLMQSETAVQDLWVNLEPQGKIHVIIELKNRTDKAKAEAVVEHTVAVNKEFKERAGFNRRRGAMRRRVHQVNGHKFMATFLRQPTFCSHCREFIWGIGKQGYQCQVCTLVVHKKCHLSVVSKCPGMRDEQPAKVEMVPAGQRFNVNLPHRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCETCGMNVHKRCQKNVANTCGINTKQMAEILSSLGISPD... | dorsal/ventral axis specification Golgi organization intracellular signal transduction lipid droplet organization long-term memory negative regulation of cell population proliferation protein phosphorylation response to ethanol plasma membrane ATP binding diacylglycerol-dependent serine/threonine kinase activity metal ... |
signal peptide processing | endoplasmic reticulum membrane; signal peptidase complex | peptidase activity serine-type endopeptidase activity | Canis lupus familiaris | Direct protein sequencing Endoplasmic reticulum Hydrolase Membrane Protease Reference proteome Signal-anchor Transmembrane Transmembrane helix | MVRAGAVGTH | MVRAGAVGTHLPASGLDIFGDLRKMNKRQLYYQVLNFAMIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGDLLFLTNFREDPIRAGEIVVFKVEGRDIPIVHRVIKVHEKDNGDIKFLTKGDNNEVDDRGLYKEGQNWLEKKDVVGRARGFLPYVGMVTIIMNDYPKFKYALLAVMGAYVLLKRES | signal peptide processing endoplasmic reticulum membrane; signal peptidase complex peptidase activity serine-type endopeptidase activity Canis lupus familiaris Direct protein sequencing Endoplasmic reticulum Hydrolase Membrane Protease Reference proteome Signal-anchor Transmembrane Transmembrane helix MVRAGAVGTH MVRAG... |
cell division chromosome segregation co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway deactivation of mitotic spindle assembly checkpoint positive regulation of attachment of mitotic spindle microtubules to kinetochore positive regulation of establishment of cell polarity regulating cell ... | cell cortex of growing cell tip; cell cortex of non-growing cell tip; cell division site; cell tip; CENP-A containing chromatin; chromatin; cytoplasm; cytosol; DPS complex; euchromatin; mRNA cleavage and polyadenylation specificity factor complex; nucleus; protein phosphatase type 1 complex; PTW/PP1 phosphatase complex... | metal ion binding myosin phosphatase activity protein serine/threonine phosphatase activity RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity | Schizosaccharomyces pombe | Cell cycle Cell division Hydrolase Manganese Metal-binding Mitosis Nucleus Phosphoprotein Protein phosphatase Reference proteome | MSNPDVDLDS | MSNPDVDLDSIIDRLLEVRGSRPGRQVQLSEDEIRFLCNKAREIFISQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLEVICLLLAYKIKYPENFFILRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIIDEKIFTMHGGLSPDLNSMDQIQRIMRPTDVPDTGLLCDLLWSDPDKDLTGWGDNDRGVSFTFGPDVVSRFLHKHDMDLVCRAHQVVEDGYEFFSKRQLVTLFSAPNYCGEFDNAGAMMSVDESLLCSFQILKPAEKKQRYGYQGSSQNWHMTPPRK... | cell division chromosome segregation co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway deactivation of mitotic spindle assembly checkpoint positive regulation of attachment of mitotic spindle microtubules to kinetochore positive regulation of establishment of cell polarity regulating cell ... |
cellular response to retinoic acid regulation of DNA-templated transcription regulation of transcription by RNA polymerase II spermatogenesis | nucleus; perinuclear region of cytoplasm | DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific metal ion binding RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific DNA binding | Homo sapiens | DNA-binding Isopeptide bond Metal-binding Nucleus Reference proteome Repeat Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | MTAELREAMA | MTAELREAMALAPWGPVKVKKEEEEEENFPGQASSQQVHSENIKVWAPVQGLQTGLDGSEEEEKGQNISWDMAVVLKATQEAPAASTLGSYSLPGTLAKSEILETHGTMNFLGAETKNLQLLVPKTEICEEAEKPLIISERIQKADPQGPELGEACEKGNMLKRQRIKREKKDFRQVIVNDCHLPESFKEEENQKCKKSGGKYSLNSGAVKNPKTQLGQKPFTCSVCGKGFSQSANLVVHQRIHTGEKPFECHECGKAFIQSANLVVHQRIHTGQKPYVCSKCGKAFTQSSNLTVHQKIHSLEKTFKCNECEKAFSYSSQ... | cellular response to retinoic acid regulation of DNA-templated transcription regulation of transcription by RNA polymerase II spermatogenesis nucleus; perinuclear region of cytoplasm DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific metal ion bin... |
bone morphogenesis bone resorption defense response to Gram-positive bacterium dephosphorylation negative regulation of inflammatory response negative regulation of interleukin-1 beta production negative regulation of interleukin-12 production negative regulation of macrophage cytokine production negative regulation of... | cytosol; lysosome; membrane | acid phosphatase activity ferric iron binding ferrous iron binding | Homo sapiens | 3D-structure Direct protein sequencing Disease variant Disulfide bond Glycoprotein Hydrolase Iron Lysosome Metal-binding Reference proteome Signal | MDMWTALLIL | MDMWTALLILQALLLPSLADGATPALRFVAVGDWGGVPNAPFHTAREMANAKEIARTVQILGADFILSLGDNFYFTGVQDINDKRFQETFEDVFSDRSLRKVPWYVLAGNHDHLGNVSAQIAYSKISKRWNFPSPFYRLHFKIPQTNVSVAIFMLDTVTLCGNSDDFLSQQPERPRDVKLARTQLSWLKKQLAAAREDYVLVAGHYPVWSIAEHGPTHCLVKQLRPLLATYGVTAYLCGHDHNLQYLQDENGVGYVLSGAGNFMDPSKRHQRKVPNGYLRFHYGTEDSLGGFAYVEISSKEMTVTYIEASGKSLFKTRLP... | bone morphogenesis bone resorption defense response to Gram-positive bacterium dephosphorylation negative regulation of inflammatory response negative regulation of interleukin-1 beta production negative regulation of interleukin-12 production negative regulation of macrophage cytokine production negative regulation of... |
auxin-activated signaling pathway cytokinesis by cell plate formation positive regulation of cell division positive regulation of cell size positive regulation of DNA endoreduplication unidimensional cell growth | endoplasmic reticulum lumen | auxin binding zinc ion binding | Zea mays | 3D-structure Auxin signaling pathway Direct protein sequencing Disulfide bond Endoplasmic reticulum Glycoprotein Metal-binding Receptor Reference proteome Signal Zinc | MAPDLSELAA | MAPDLSELAAAAAARGAYLAGVGVAVLLAASFLPVAESSCVRDNSLVRDISQMPQSSYGIEGLSHITVAGALNHGMKEVEVWLQTISPGQRTPIHRHSCEEVFTVLKGKGTLLMGSSSLKYPGQPQEIPFFQNTTFSIPVNDPHQVWNSDEHEDLQVLVIISRPPAKIFLYDDWSMPHTAAVLKFPFVWDEDCFEAAKDEL | auxin-activated signaling pathway cytokinesis by cell plate formation positive regulation of cell division positive regulation of cell size positive regulation of DNA endoreduplication unidimensional cell growth endoplasmic reticulum lumen auxin binding zinc ion binding Zea mays 3D-structure Auxin signaling pathway Dir... |
calcium ion transport intracellular calcium ion homeostasis negative regulation of apoptotic process negative regulation of ectoderm development negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage regulation of apoptotic process response to virus stem cell population maintenance | cytoplasm; cytoplasmic microtubule; cytosol; extracellular exosome; extracellular space; multivesicular body; nucleoplasm; nucleus; spindle pole | calcium ion binding DNA-binding transcription factor binding RNA binding | Homo sapiens | 3D-structure Alternative splicing Calcium Cytoplasm Direct protein sequencing Phosphoprotein Reference proteome | MIIYRDLISH | MIIYRDLISHDEMFSDIYKIREIADGLCLEVEGKMVSRTEGNIDDSLIGGNASAEGPEGEGTESTVITGVDIVMNHHLQETSFTKEAYKKYIKDYMKSIKGKLEEQRPERVKPFMTGAAEQIKHILANFKNYQFFIGENMNPDGMVALLDYREDGVTPYMIFFKDGLEMEKC | calcium ion transport intracellular calcium ion homeostasis negative regulation of apoptotic process negative regulation of ectoderm development negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage regulation of apoptotic process response to virus stem cell population maintenance cytop... |
malate metabolic process NADH metabolic process NADP metabolic process protein homotetramerization pyruvate metabolic process regulation of NADP metabolic process response to hormone | cytoplasm; cytosol; mitochondrion | identical protein binding magnesium ion binding malate dehydrogenase (decarboxylating) (NADP+) activity malic enzyme activity manganese ion binding NAD binding NADP binding oxaloacetate decarboxylase activity | Rattus norvegicus | Acetylation Cytoplasm Direct protein sequencing Metal-binding NADP Oxidoreductase Phosphoprotein Reference proteome | MDPRAPRRRH | MDPRAPRRRHTHQRGYLLTRDPHLNKDLAFTLEERQQLKIHGLLPPCIVNQEIQVLRVIKNFERLNSDFDRYLLLMDLQDRNEKLFYSVLMSNVEKFMPIVYTPTVGLACQQYSLAFRKPRGLFISIHDKGHIASVLNAWPEDVVKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGVNPQQCLPITLDVGTENEELLKDPLYIGLRHRRVRGPEYDAFLDEFMEAASSKYGMNCLIQFEDFANLNAFRLLNKYRNKYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTVLFQGAGEAALGIAHLIVMAMEKE... | malate metabolic process NADH metabolic process NADP metabolic process protein homotetramerization pyruvate metabolic process regulation of NADP metabolic process response to hormone cytoplasm; cytosol; mitochondrion identical protein binding magnesium ion binding malate dehydrogenase (decarboxylating) (NADP+) activity... |
negative stranded viral RNA replication RNA-templated viral transcription suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhib... | helical viral capsid; host cell cytoplasm; ribonucleoprotein complex; viral nucleocapsid | 3'-5' exonuclease activity identical protein binding metal ion binding RNA binding | Lassa virus | 3D-structure Capsid protein Helical capsid protein Host cytoplasm Host-virus interaction Hydrolase Inhibition of host IKBKE by virus Inhibition of host innate immune response by virus Inhibition of host RLR pathway by virus Interferon antiviral system evasion Manganese Metal-binding Reference proteome Ribonucleoprotein... | MSASKEIKSF | MSASKEIKSFLWTQSLRRELSGYCSNIKLQVVKDAQALLHGLDFSEVSNVQRLMRKERRDDNDLKRLRDLNQAVNNLVELKSTQQKSILRVGTLTSDDLLILAADLEKLKSKVIRTERPLSAGVYMGNLSSQQLDQRRALLNMIGMSGGNQGARAGRDGVVRVWDVKNAELLNNQFGTMPSLTLACLTKQGQVDLNDAVQALTDLGLIYTAKYPNTSDLDRLTQSHPILNMIDTKKSSLNISGYNFSLGAAVKAGACMLDGGNMLETIKVSPQTMDGILKSILKVKKALGMFISDTPGERNPYENILYKICLSGDGWPYI... | negative stranded viral RNA replication RNA-templated viral transcription suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhib... |
carbohydrate metabolic process ethanol metabolic process flight behavior glycerol-3-phosphate catabolic process glycerol-3-phosphate metabolic process glycerophospholipid metabolic process NADH metabolic process NADH oxidation response to hyperoxia triglyceride metabolic process | cytosol; glycerol-3-phosphate dehydrogenase complex; M band; Z disc | glycerol-3-phosphate dehydrogenase activity NAD binding protein homodimerization activity | Drosophila melanogaster | Alternative splicing Cytoplasm Direct protein sequencing NAD Oxidoreductase Reference proteome | MADKVNVCIV | MADKVNVCIVGSGNWGSAIAKIVGANAAALPEFEERVTMFVYEELIDGKKLTEIINETHENVKYLKGHKLPPNVVAVPDLVEAAKNADILIFVVPHQFIPNFCKQLLGKIKPNAIAISLIKGFDKAEGGGIDLISHIITRHLKIPCAVLMGANLANEVAEGNFCETTIGCTDKKYGKVLRDLFQANHFRVVVVDDADAVEVCGALKNIVACGAGFVDGLKLGDNTKAAVIRLGLMEMIRFVDVFYPGSKLSTFFESCGVADLITTCYGGRNRRVSEAFVTSGKTIEELEKEMLNGQKLQGPPTAEEVNYMLKNKGLEDKF... | carbohydrate metabolic process ethanol metabolic process flight behavior glycerol-3-phosphate catabolic process glycerol-3-phosphate metabolic process glycerophospholipid metabolic process NADH metabolic process NADH oxidation response to hyperoxia triglyceride metabolic process cytosol; glycerol-3-phosphate dehydrogen... |
cellular response to interleukin-4 cellular response to lead ion heme A biosynthetic process heme B biosynthetic process heme biosynthetic process heme O biosynthetic process negative regulation of proteasomal protein catabolic process protein homooligomerization protoporphyrinogen IX biosynthetic process response to a... | cytosol; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; nucleus; secretory granule lumen | catalytic activity identical protein binding porphobilinogen synthase activity proteasome core complex binding zinc ion binding | Homo sapiens | 3D-structure Allosteric enzyme Alternative splicing Direct protein sequencing Disease variant Heme biosynthesis Lyase Metal-binding Phosphoprotein Porphyrin biosynthesis Reference proteome Zinc | MQPQSVLHSG | MQPQSVLHSGYFHPLLRAWQTATTTLNASNLIYPIFVTDVPDDIQPITSLPGVARYGVKRLEEMLRPLVEEGLRCVLIFGVPSRVPKDERGSAADSEESPAIEAIHLLRKTFPNLLVACDVCLCPYTSHGHCGLLSENGAFRAEESRQRLAEVALAYAKAGCQVVAPSDMMDGRVEAIKEALMAHGLGNRVSVMSYSAKFASCFYGPFRDAAKSSPAFGDRRCYQLPPGARGLALRAVDRDVREGADMLMVKPGMPYLDIVREVKDKHPDLPLAVYHVSGEFAMLWHGAQAGAFDLKAAVLEAMTAFRRAGADIIITYYT... | cellular response to interleukin-4 cellular response to lead ion heme A biosynthetic process heme B biosynthetic process heme biosynthetic process heme O biosynthetic process negative regulation of proteasomal protein catabolic process protein homooligomerization protoporphyrinogen IX biosynthetic process response to a... |
N-acetylneuraminate metabolic process negative regulation of chemotaxis negative regulation of macrophage apoptotic process positive regulation of mononuclear cell proliferation protein glycosylation protein N-linked glycosylation via asparagine regulation of substrate adhesion-dependent cell spreading response to etha... | extracellular region; Golgi apparatus; Golgi cisterna membrane; Golgi medial cisterna; Golgi membrane; Golgi trans cisterna | beta-galactoside alpha-2,6-sialyltransferase activity protein homodimerization activity sialyltransferase activity | Rattus norvegicus | 3D-structure Alternative promoter usage Alternative splicing Direct protein sequencing Disulfide bond Glycoprotein Glycosyltransferase Golgi apparatus Membrane Phosphoprotein Reference proteome Secreted Signal-anchor Transferase Transmembrane Transmembrane helix | MIHTNLKKKF | MIHTNLKKKFSLFILVFLLFAVICVWKKGSDYEALTLQAKEFQMPKSQEKVAMGSASQVVFSNSKQDPKEDIPILSYHRVTAKVKPQPSFQVWDKDSTYSKLNPRLLKIWRNYLNMNKYKVSYKGPGPGVKFSVEALRCHLRDHVNVSMIEATDFPFNTTEWEGYLPKENFRTKVGPWQRCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTDNFQQDVGSKTTIRLMNSQLVTTEKRFLKDSLYTEGILIVWDPSVYHADIPKWYQKPDYNFFETYKSYRRLNPSQPFYILKPQMPWELWDIIQEISADLIQPNPPSS... | N-acetylneuraminate metabolic process negative regulation of chemotaxis negative regulation of macrophage apoptotic process positive regulation of mononuclear cell proliferation protein glycosylation protein N-linked glycosylation via asparagine regulation of substrate adhesion-dependent cell spreading response to etha... |
carbohydrate metabolic process glycosaminoglycan metabolic process | lysosome; membrane | beta-N-acetylhexosaminidase activity N-acetyl-beta-D-galactosaminidase activity | Dictyostelium discoideum | Direct protein sequencing Glycoprotein Glycosidase Hydrolase Lysosome Reference proteome Signal | MIKKIILFFA | MIKKIILFFAVLIAIVIGQQPLNVVPYPQQVSIGTCVIPVAPGSILIESNIESATFSVSMDRYTNLFFPFSNESEPSSNESFLLSVTIYSDDETLQLGIDESYSLSIEQGSYQLKATNIYGAMRGLETFKQLIVYNELENSYSIVCVSISDSPRYPWRGFMVDSARHYIPKNMILHMIDSLGFSKFNTLHWHMVDAVAFPVESTTYPDLTKGAFSPSATFSHDDIQEVVAYAKTYGIRVIPEFDIPGHAAAWGIGYPELVATCPDYAANVNNIPLDISNPATFTFIQNLFTEIAPLFIDNYFHTGGDELVTGCWLEDPAI... | carbohydrate metabolic process glycosaminoglycan metabolic process lysosome; membrane beta-N-acetylhexosaminidase activity N-acetyl-beta-D-galactosaminidase activity Dictyostelium discoideum Direct protein sequencing Glycoprotein Glycosidase Hydrolase Lysosome Reference proteome Signal MIKKIILFFA MIKKIILFFAVLIAIVIGQQPL... |
immune response negative regulation of cell population proliferation negative regulation of hormone secretion oncostatin-M-mediated signaling pathway positive regulation of acute inflammatory response positive regulation of cell division positive regulation of cell population proliferation positive regulation of inflam... | extracellular region; extracellular space | cytokine activity growth factor activity oncostatin-M receptor binding | Homo sapiens | 3D-structure Cleavage on pair of basic residues Cytokine Direct protein sequencing Disulfide bond Glycoprotein Growth regulation Mitogen Reference proteome Secreted Signal | MGVLLTQRTL | MGVLLTQRTLLSLVLALLFPSMASMAAIGSCSKEYRVLLGQLQKQTDLMQDTSRLLDPYIRIQGLDVPKLREHCRERPGAFPSEETLRGLGRRGFLQTLNATLGCVLHRLADLEQRLPKAQDLERSGLNIEDLEKLQMARPNILGLRNNIYCMAQLLDNSDTAEPTKAGRGASQPPTPTPASDAFQRKLEGCRFLHGYHRFMHSVGRVFSKWGESPNRSRRHSPHQALRKGVRRTRPSRKGKRLMTRGQLPR | immune response negative regulation of cell population proliferation negative regulation of hormone secretion oncostatin-M-mediated signaling pathway positive regulation of acute inflammatory response positive regulation of cell division positive regulation of cell population proliferation positive regulation of inflam... |
activation of blood coagulation via clotting cascade activation of cysteine-type endopeptidase activity involved in apoptotic process activation of plasma proteins involved in acute inflammatory response blood coagulation cytokine-mediated signaling pathway positive regulation of angiogenesis positive regulation of cel... | cell surface; collagen-containing extracellular matrix; external side of plasma membrane; extracellular space; membrane; plasma membrane; serine-type peptidase complex | cytokine receptor activity phospholipid binding protease binding | Homo sapiens | 3D-structure Alternative splicing Blood coagulation Disulfide bond Glycoprotein Hemostasis Lipoprotein Membrane Palmitate Reference proteome Secreted Signal Transmembrane Transmembrane helix | METPAWPRVP | METPAWPRVPRPETAVARTLLLGWVFAQVAGASGTTNTVAAYNLTWKSTNFKTILEWEPKPVNQVYTVQISTKSGDWKSKCFYTTDTECDLTDEIVKDVKQTYLARVFSYPAGNVESTGSAGEPLYENSPEFTPYLETNLGQPTIQSFEQVGTKVNVTVEDERTLVRRNNTFLSLRDVFGKDLIYTLYYWKSSSSGKKTAKTNTNEFLIDVDKGENYCFSVQAVIPSRTVNRKSTDSPVECMGQEKGEFREIFYIIGAVVFVVIILVIILAISLHKCRKAGVGQSWKENSPLNVS | activation of blood coagulation via clotting cascade activation of cysteine-type endopeptidase activity involved in apoptotic process activation of plasma proteins involved in acute inflammatory response blood coagulation cytokine-mediated signaling pathway positive regulation of angiogenesis positive regulation of cel... |
defense response to bacterium defense response to nematode immune response negative regulation of interleukin-10 production negative regulation of macrophage cytokine production positive regulation of interleukin-4 production | collagen-containing extracellular matrix; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; transport vesicle | carbohydrate binding extracellular matrix structural constituent conferring compression resistance heparin binding | Homo sapiens | 3D-structure Alternative splicing Antibiotic Antimicrobial Cytoplasmic vesicle Direct protein sequencing Disulfide bond Glycoprotein Heparin-binding Immunity Lectin Nitration Proteoglycan Reference proteome Secreted Signal | MKLPLLLALL | MKLPLLLALLFGAVSALHLRSETSTFETPLGAKTLPEDEETPEQEMEETPCRELEEEEEWGSGSEDASKKDGAVESISVPDMVDKNLTCPEEEDTVKVVGIPGCQTCRYLLVRSLQTFSQAWFTCRRCYRGNLVSIHNFNINYRIQCSVSALNQGQVWIGGRITGSGRCRRFQWVDGSRWNFAYWAAHQPWSRGGHCVALCTRGGHWRRAHCLRRLPFICSY | defense response to bacterium defense response to nematode immune response negative regulation of interleukin-10 production negative regulation of macrophage cytokine production positive regulation of interleukin-4 production collagen-containing extracellular matrix; extracellular exosome; extracellular region; ficolin... |
regulation of intracellular pH response to alkaline pH response to salt stress | plasma membrane | cardiolipin binding sodium:proton antiporter activity | Escherichia coli | 3D-structure Antiport Cell inner membrane Cell membrane Direct protein sequencing Ion transport Membrane Reference proteome Sodium Sodium transport Transmembrane Transmembrane helix Transport | MKHLHRFFSS | MKHLHRFFSSDASGGIILIIAAILAMIMANSGATSGWYHDFLETPVQLRVGSLEINKNMLLWINDALMAVFFLLVGLEVKRELMQGSLASLRQAAFPVIAAIGGMIVPALLYLAFNYADPITREGWAIPAATDIAFALGVLALLGSRVPLALKIFLMALAIIDDLGAIIIIALFYTNDLSMASLGVAAVAIAVLAVLNLCGARRTGVYILVGVVLWTAVLKSGVHATLAGVIVGFFIPLKEKHGRSPAKRLEHVLHPWVAYLILPLFAFANAGVSLQGVTLDGLTSILPLGIIAGLLIGKPLGISLFCWLALRLKLAHLP... | regulation of intracellular pH response to alkaline pH response to salt stress plasma membrane cardiolipin binding sodium:proton antiporter activity Escherichia coli 3D-structure Antiport Cell inner membrane Cell membrane Direct protein sequencing Ion transport Membrane Reference proteome Sodium Sodium transport Transm... |
glutathione derivative biosynthetic process glutathione metabolic process prostaglandin metabolic process response to bacterium response to stilbenoid xenobiotic metabolic process | cytosol | dinitrosyl-iron complex binding fatty acid binding glutathione binding glutathione peroxidase activity glutathione transferase activity protein homodimerization activity steroid delta-isomerase activity | Mus musculus | 3D-structure Acetylation Direct protein sequencing Isomerase Lipid metabolism Oxidoreductase Peroxidase Reference proteome Transferase | MAGKPVLHYF | MAGKPVLHYFNARGRMECIRWLLAAAGVEFEEKFIQSPEDLEKLKKDGNLMFDQVPMVEIDGMKLAQTRAILNYIATKYDLYGKDMKERALIDMYSEGILDLTEMIGQLVLCPPDQREAKTALAKDRTKNRYLPAFEKVLKSHGQDYLVGNRLTRVDIHLLEVLLYVEEFDASLLTPFPLLKAFKSRISSLPNVKKFLQPGSQRKPPMDAKQIQEARKAFKIQ | glutathione derivative biosynthetic process glutathione metabolic process prostaglandin metabolic process response to bacterium response to stilbenoid xenobiotic metabolic process cytosol dinitrosyl-iron complex binding fatty acid binding glutathione binding glutathione peroxidase activity glutathione transferase activ... |
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity | early endosome membrane; ER to Golgi transport vesicle membrane; external side of plasma membrane; extracellular space; lumenal side of endoplasmic reticulum membrane; MHC class I protein complex; phagocytic vesicle membrane; recycling endosome membrane | peptide antigen binding signaling receptor binding | Pan troglodytes | Disulfide bond Glycoprotein Immunity Membrane MHC I Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix | MAVMPPRTLL | MAVMPPRTLLLLLSGALALTQTWAGSHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDQETRNMKASAQTDRVDLGTLRGYYNQSEDGSHTIQIMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAAAMAAQITKRKWEAAHAAEQLRAYLEGRCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAVITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQPTIPIVGIIAGLVLLGA... | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity early endosome membrane; ER to Golgi transport vesicle ... |
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity | early endosome membrane; ER to Golgi transport vesicle membrane; external side of plasma membrane; extracellular space; lumenal side of endoplasmic reticulum membrane; MHC class I protein complex; phagocytic vesicle membrane; recycling endosome membrane | peptide antigen binding signaling receptor binding | Pan troglodytes | Disulfide bond Glycoprotein Immunity Membrane MHC I Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix | APRTVLLLLS | APRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFITVGYVDDTQFVRFDSDAASPRMEPRAPWIEQEGPEYWDRETRNMKASAQTDRENLRIALRYYNQSEAGSHTWQTMYGCDMGPDGRLLRGYGQYAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAAREAEQRRAYLEGTCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPEGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQSTIPIVGIVAGLAVLVVTVAV... | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity early endosome membrane; ER to Golgi transport vesicle ... |
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity | early endosome membrane; ER to Golgi transport vesicle membrane; external side of plasma membrane; extracellular space; lumenal side of endoplasmic reticulum membrane; MHC class I protein complex; phagocytic vesicle membrane; recycling endosome membrane | peptide antigen binding signaling receptor binding | Pan troglodytes | Disulfide bond Glycoprotein Immunity Membrane MHC I Reference proteome Signal Transmembrane Transmembrane helix | MQVTAPRTVL | MQVTAPRTVLLLLSAALALTETWAGSHSMKYFYTAVSRPGRGEPRFISVGYVDDTQFVWFDSDAASPREEPRAPWIEQEGPEYWDRETQISKTNAQTYRESLRNLRGYYNQSEAGSHIIQRMYGCDMGPDGRLLRGYEQYAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAARWAEQLRAYLEGTCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQSTIPIVGIVAGLAVLAV... | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity early endosome membrane; ER to Golgi transport vesicle ... |
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity | external side of plasma membrane; extracellular space; lumenal side of endoplasmic reticulum membrane; MHC class I protein complex; phagocytic vesicle membrane | peptide antigen binding signaling receptor binding | Bos taurus | Disulfide bond Glycoprotein Immunity Membrane MHC I Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix | MGPRALLLLL | MGPRALLLLLSGVLILTETRAGSHSLRYFSTAVSRPGLGEPRYLEVGYVDDTQFVQFDSDAPNPRMEPRARWVEQEGPEYWDRNTRNAKGNAQSFRVNLNTLRGYYNQSEAGSHTLQWMSGCDVGPDGALRRGFMQYGYDGRDYLALNEDLRSWTAGETEAQITKRKWEAAGYAEVQRNYLEGECVEWLRRYLENGKDTLLRADPPKAHVTHHPISGREVTLRCWALGFYPEEISLTWQHDGEDQTQDMELVETRPSGDGTFQKWAALVVPSGDEQRYTCRVQHEGLQEPLTLRWEPPQPSFLTMGIIVGLVLLVVTGAV... | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity external side of plasma membrane; extracellular space; ... |
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity | external side of plasma membrane; extracellular space; lumenal side of endoplasmic reticulum membrane; MHC class I protein complex; phagocytic vesicle membrane | peptide antigen binding signaling receptor binding | Bos taurus | Disulfide bond Glycoprotein Immunity Membrane MHC I Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix | MRVMRVMRPR | MRVMRVMRPRTLLLLLSGVLVLTETLAGSHSLRYFYTGVSRPGLGEPRFIAVGYVDDTQFVRFDSDAPNPREEPRVPWMEQEGPEYWDRNTRIYKDTAQIFRVDLNTLRGYYNQSETGSHNIQAMYGCDVGPDGRLLRGFWQFGYDGRDYIALNEELRSWTAADTAAQITKRKWEAAGAAETWRNYLEGECVEWLRRYLENGKDTLLRADPPKAHVTHHSISDREVTLRCWALGFYPEEISLTWQREGEDQTQDMELVETRPSGDGTFQKWAALVVPSGEEQRYTCRVQHEGLQEPLTLRWEPPQTSFLIMGIIVGLVLL... | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity external side of plasma membrane; extracellular space; ... |
adaptive immune response antigen processing and presentation of exogenous peptide antigen via MHC class II peptide antigen assembly with MHC class II protein complex positive regulation of immune response positive regulation of T cell activation | clathrin-coated endocytic vesicle membrane; endocytic vesicle membrane; ER to Golgi transport vesicle membrane; Golgi membrane; late endosome membrane; lumenal side of endoplasmic reticulum membrane; lysosomal membrane; MHC class II protein complex; plasma membrane; trans-Golgi network membrane; transport vesicle membr... | MHC class II protein complex binding peptide antigen binding | Homo sapiens | Adaptive immunity Cell membrane Disulfide bond Endoplasmic reticulum Endosome Glycoprotein Golgi apparatus Immunity Isopeptide bond Lysosome Membrane MHC II Reference proteome Signal Transmembrane Transmembrane helix Ubl conjugation | MVCLKLPGGS | MVCLKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYIYNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTVQRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGLLFLGTGLFIYFRNQKGHSGLQPTGLLS | adaptive immune response antigen processing and presentation of exogenous peptide antigen via MHC class II peptide antigen assembly with MHC class II protein complex positive regulation of immune response positive regulation of T cell activation clathrin-coated endocytic vesicle membrane; endocytic vesicle membrane; ER... |
adaptive immune response antigen processing and presentation of exogenous peptide antigen via MHC class II negative regulation of antigen processing and presentation of peptide antigen via MHC class II peptide antigen assembly with MHC class II protein complex positive regulation of immune response positive regulation ... | late endosome membrane; lysosomal membrane; lysosome; MHC class II protein complex | MHC class II protein complex binding MHC class II receptor activity peptide antigen binding | Homo sapiens | 3D-structure Adaptive immunity Disulfide bond Endosome Glycoprotein Immunity Lysosome Membrane MHC II Reference proteome Signal Transmembrane Transmembrane helix | MGSGWVPWVV | MGSGWVPWVVALLVNLTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDSDVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTVYPERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVMLEMTPELGHVYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQLRAQKGYVRTQMSGNEVSRAVLLPQSC | adaptive immune response antigen processing and presentation of exogenous peptide antigen via MHC class II negative regulation of antigen processing and presentation of peptide antigen via MHC class II peptide antigen assembly with MHC class II protein complex positive regulation of immune response positive regulation ... |
adaptation of signaling pathway adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway aggregation involved in sorocarp development cGMP-mediated signaling chemotaxis desensitization of G protein-coupled receptor signaling... | cell leading edge; cell surface; cytosol; early endosome; plasma membrane | adenylate cyclase regulator activity cAMP binding cAMP receptor activity G protein-coupled chemoattractant receptor activity G protein-coupled receptor activity GTPase regulator activity protein kinase regulator activity | Dictyostelium discoideum | G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MGLLDGNPAN | MGLLDGNPANETSLVLLLFADFSSMLGCMAVLIGFWRLKLLRNHVTKVIACFCATSFCKDFPSTILTLTNTAVNGGFPCYLYAIVITYGSFACWLWTLCLAISIYMLIVKREPEPERFEKYYYLLCWGLPLISTIVMLAKNTVQFVGNWCWIGVSFTGYRFGLFYGPFLFIWAISAVLVGLTSRYTYVVIHNGVSDNKEKHLTYQFKLINYIIVFLVCWVFAVVNRIVNGLNMFPPALNILHTYLSVSHGFWASVTFIYNNPLMWRYFGAKILTVFTFFGYFTDVQKKLEKNKNNNNPSPYSSSRGTSGKTMGGHPTGDD... | adaptation of signaling pathway adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway aggregation involved in sorocarp development cGMP-mediated signaling chemotaxis desensitization of G protein-coupled receptor signaling... |
actin crosslink formation actin filament bundle assembly actin filament network formation animal organ regeneration cell migration cortical actin cytoskeleton organization extracellular matrix disassembly positive regulation of podosome assembly protein kinase A signaling regulation of intracellular protein transport T... | actin cytoskeleton; actin filament; actin filament bundle; cell junction; cytoplasm; cytosol; extracellular exosome; extracellular space; filopodium; focal adhesion; glial cell projection; perinuclear region of cytoplasm; phagocytic cup; plasma membrane; podosome; ruffle; ruffle membrane | actin binding actin filament binding calcium ion binding GTPase binding integrin binding | Homo sapiens | 3D-structure Acetylation Actin-binding Alternative splicing Calcium Cell junction Cell membrane Cell projection Chromosomal rearrangement Cytoplasm Cytoskeleton Direct protein sequencing Disease variant Membrane Metal-binding Phosphoprotein Reference proteome Repeat | MARGSVSDEE | MARGSVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGRISFDEFIKIFHGLKSTDVAKTFRKAINKKEGICAIGGTSEQSSVGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTINKKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIELSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYHLLEQVAPKGDEEGVPAVVI... | actin crosslink formation actin filament bundle assembly actin filament network formation animal organ regeneration cell migration cortical actin cytoskeleton organization extracellular matrix disassembly positive regulation of podosome assembly protein kinase A signaling regulation of intracellular protein transport T... |
actin filament bundle assembly actin filament network formation bone development | actin filament; actin filament bundle; cytoplasm; cytosol; plasma membrane | actin filament binding calcium ion binding | Homo sapiens | 3D-structure Actin-binding Alternative splicing Calcium Cytoplasm Direct protein sequencing Disease variant Metal-binding Phosphoprotein Reference proteome Repeat | MDEMATTQIS | MDEMATTQISKDELDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKLMLDGDRNKDGKISFDEFVYIFQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSKAYFHLLNQIAPKGQKEGEPR... | actin filament bundle assembly actin filament network formation bone development actin filament; actin filament bundle; cytoplasm; cytosol; plasma membrane actin filament binding calcium ion binding Homo sapiens 3D-structure Actin-binding Alternative splicing Calcium Cytoplasm Direct protein sequencing Disease variant ... |
amyloid-beta metabolic process proteolysis translational termination | cytosol; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; nuclear membrane | identical protein binding omega peptidase activity RNA binding serine-type endopeptidase activity | Homo sapiens | Acetylation Cytoplasm Direct protein sequencing Hydrolase Phosphoprotein Reference proteome | MERQVLLSEP | MERQVLLSEPEEAAALYRGLSRQPALSAACLGPEVTTQYGGQYRTVHTEWTQRDLERMENIRFCRQYLVFHDGDSVVFAGPAGNSVETRGELLSRESPSGTMKAVLRKAGGTGPGEEKQFLEVWEKNRKLKSFNLSALEKHGPVYEDDCFGCLSWSHSETHLLYVAEKKRPKAESFFQTKALDVSASDDEIARLKKPDQAIKGDQFVFYEDWGENMVSKSIPVLCVLDVESGNISVLEGVPENVSPGQAFWAPGDAGVVFVGWWHEPFRLGIRFCTNRRSALYYVDLIGGKCELLSDDSLAVSSPRLSPDQCRIVYLQYP... | amyloid-beta metabolic process proteolysis translational termination cytosol; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; nuclear membrane identical protein binding omega peptidase activity RNA binding serine-type endopeptidase activity Homo sapiens Acetylation Cytoplasm Direct protein se... |
phosphorelay signal transduction system positive regulation of DNA-templated transcription | cytoplasm | DNA binding | Bacillus subtilis | Activator Cytoplasm DNA-binding Phosphoprotein Reference proteome Repressor Transcription Transcription regulation Two-component regulatory system | MTKVNIVIID | MTKVNIVIIDDHQLFREGVKRILDFEPTFEVVAEGDDGDEAARIVEHYHPDVVIMDINMPNVNGVEATKQLVELYPESKVIILSIHDDENYVTHALKTGARGYLLKEMDADTLIEAVKVVAEGGSYLHPKVTHNLVNEFRRLATSGVSAHPQHEVYPEIRRPLHILTRRECEVLQMLADGKSNRGIGESLFISEKTVKNHVSNILQKMNVNDRTQAVVVAIKNGWVEMR | phosphorelay signal transduction system positive regulation of DNA-templated transcription cytoplasm DNA binding Bacillus subtilis Activator Cytoplasm DNA-binding Phosphoprotein Reference proteome Repressor Transcription Transcription regulation Two-component regulatory system MTKVNIVIID MTKVNIVIIDDHQLFREGVKRILDFEPTFEV... |
asexual sporulation proteolysis sporulation resulting in formation of a cellular spore | plasma membrane | aspartic-type endopeptidase activity peptidase activity protein self-association | Bacillus subtilis | Aspartyl protease Cell membrane Hydrolase Membrane Protease Reference proteome Sporulation Transmembrane Transmembrane helix | MKIYLDVIWL | MKIYLDVIWLLNFCFDALLLLLTAFILKRHVKKRRLVGGAFIGSSIVLLMFTPFSPIVEHPAGKLAFSVVIVVVTFGFKRFRFFFQNLFSFYFATFLMGGGIIGAHSLLQSNSIVQNGVMITNQTGFGDPISWLFIVGGFPALWFFSKRRIEDIETKNIQYEERVSVQADLGSQTLHVRGLIDSGNQLYDPLTKTPVMIIYIDKLEPIFGTAETMIIRNTDPLEAIEQLDDSFRFLDKMRLIPYRGVGQQNQFLLCVKPDHVTIMTKEEMISADKCLIGISTTKLSADGEFDAIIHPKMLSGKAVKHVS | asexual sporulation proteolysis sporulation resulting in formation of a cellular spore plasma membrane aspartic-type endopeptidase activity peptidase activity protein self-association Bacillus subtilis Aspartyl protease Cell membrane Hydrolase Membrane Protease Reference proteome Sporulation Transmembrane Transmembrane... |
amino acid catabolic process fatty acid beta-oxidation using acyl-CoA dehydrogenase respiratory electron transport chain | electron transfer flavoprotein complex; mitochondrial matrix; mitochondrion | electron transfer activity flavin adenine dinucleotide binding oxidoreductase activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Direct protein sequencing Disease variant Electron transport FAD Flavoprotein Glutaricaciduria Mitochondrion Phosphoprotein Reference proteome Transit peptide Transport | MFRAAAPGQL | MFRAAAPGQLRRAASLLRFQSTLVIAEHANDSLAPITLNTITAATRLGGEVSCLVAGTKCDKVAQDLCKVAGIAKVLVAQHDVYKGLLPEELTPLILATQKQFNYTHICAGASAFGKNLLPRVAAKLEVAPISDIIAIKSPDTFVRTIYAGNALCTVKCDEKVKVFSVRGTSFDAAATSGGSASSEKASSTSPVEISEWLDQKLTKSDRPELTGAKVVVSGGRGLKSGENFKLLYDLADQLHAAVGASRAAVDAGFVPNDMQVGQTGKIVAPELYIAVGISGAIQHLAGMKDSKTIVAINKDPEAPIFQVADYGIVADLF... | amino acid catabolic process fatty acid beta-oxidation using acyl-CoA dehydrogenase respiratory electron transport chain electron transfer flavoprotein complex; mitochondrial matrix; mitochondrion electron transfer activity flavin adenine dinucleotide binding oxidoreductase activity Homo sapiens 3D-structure Acetylatio... |
negative regulation of muscle contraction sarcomere organization skeletal muscle contraction slow-twitch skeletal muscle fiber contraction transition between fast and slow fiber | cytosol; troponin complex | tropomyosin binding troponin T binding | Homo sapiens | Alternative splicing Disease variant Muscle protein Nemaline myopathy Phosphoprotein Reference proteome | MSDTEEQEYE | MSDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDLMAKLKQQKYEINVLYNRISHAQKFRKGAGKGRVGGRWK | negative regulation of muscle contraction sarcomere organization skeletal muscle contraction slow-twitch skeletal muscle fiber contraction transition between fast and slow fiber cytosol; troponin complex tropomyosin binding troponin T binding Homo sapiens Alternative splicing Disease variant Muscle protein Nemaline myo... |
glycogen biosynthetic process heart development | cytoplasm; cytosol; inclusion body; membrane | glucose binding glycogen (starch) synthase activity glycogen synthase activity, transferring glucose-1-phosphate | Homo sapiens | 3D-structure Allosteric enzyme Alternative splicing Diabetes mellitus Disease variant Glycogen biosynthesis Glycosyltransferase Phosphoprotein Reference proteome Transferase | MPLNRTLSMS | MPLNRTLSMSSLPGLEDWEDEFDLENAVLFEVAWEVANKVGGIYTVLQTKAKVTGDEWGDNYFLVGPYTEQGVRTQVELLEAPTPALKRTLDSMNSKGCKVYFGRWLIEGGPLVVLLDVGASAWALERWKGELWDTCNIGVPWYDREANDAVLFGFLTTWFLGEFLAQSEEKPHVVAHFHEWLAGVGLCLCRARRLPVATIFTTHATLLGRYLCAGAVDFYNNLENFNVDKEAGERQIYHRYCMERAAAHCAHVFTTVSQITAIEAQHLLKRKPDIVTPNGLNVKKFSAMHEFQNLHAQSKARIQEFVRGHFYGHLDFNL... | glycogen biosynthetic process heart development cytoplasm; cytosol; inclusion body; membrane glucose binding glycogen (starch) synthase activity glycogen synthase activity, transferring glucose-1-phosphate Homo sapiens 3D-structure Allosteric enzyme Alternative splicing Diabetes mellitus Disease variant Glycogen biosyn... |
glycogen biosynthetic process | skeletal muscle myofibril | glycogen (starch) synthase activity protein kinase binding | Oryctolagus cuniculus | Allosteric enzyme Direct protein sequencing Glycogen biosynthesis Glycosyltransferase Phosphoprotein Reference proteome Transferase | MPLSRTLSVS | MPLSRTLSVSSLPGLEDWEDEFDLENSVLFEVAWEVANKVGGIYTVLQTKAKVTGDEWGDNYFLVGPYTEQGVRTQVELLEPPTPALKRTLDSMNSKGCKVYFGRWLIEGGPLVVLLDVGASAWALERWKGELWDTCNIGVPWYDREANDAVLFGFLTTWFLGEFLAQNEEKPHVVAHFHEWLAGIGLCLCRARRLPVATIFTTHATLLGRYLCAGAVDFYNNLENFNVDKEAGERQIYHRYCMERAAAHCAHVFTTVSQITAIEAQHLLKRKPDIVTPNGLNVKKFSAMHEFQNLHAQSKARIQEFVRGHFYGHLDFNL... | glycogen biosynthetic process skeletal muscle myofibril glycogen (starch) synthase activity protein kinase binding Oryctolagus cuniculus Allosteric enzyme Direct protein sequencing Glycogen biosynthesis Glycosyltransferase Phosphoprotein Reference proteome Transferase MPLSRTLSVS MPLSRTLSVSSLPGLEDWEDEFDLENSVLFEVAWEVANKV... |
apoptotic signaling pathway cell surface receptor signaling pathway chronic inflammatory response defense response to bacterium leukocyte tethering or rolling monocyte activation negative regulation of cell adhesion negative regulation of T cell activation negative regulation of T cell proliferation negative regulation... | basement membrane; cell surface; cleavage furrow; external side of plasma membrane; extracellular space; microvillus; plasma membrane; PML body; uropod | heat shock protein binding Hsp70 protein binding protein domain specific binding transmembrane signaling receptor activity | Rattus norvegicus | Cell projection Glycoprotein Membrane Nucleus Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix Ubl conjugation | WAQVVSQENL | WAQVVSQENLPNTMTMLPFTPNSESPSTSEALSTYSSIATVPVTEDPKESISPWGQTTAPASSIPLGTPELSSFFFTSAGASGNTPVPELTTSQEVSTEASLVLFPKSSGVASDPPVTITNPATSSAVASTSLETFKGTSAPPVTVTSSTMTSGPFVATTVSSETSGPPVTMATGSLGPSKETHGLSATIATSSGESSSVAGGTPVFSTKISTTSTPNPITTVPPRPGSSGMLLVSMLIALTVVLVLVALLLLWRQRQKRRTGALTLSRGGKRNGTVDAWAGPARVPDEEATTASGSGGNKSSGAPETDGSGQRPTLTTF... | apoptotic signaling pathway cell surface receptor signaling pathway chronic inflammatory response defense response to bacterium leukocyte tethering or rolling monocyte activation negative regulation of cell adhesion negative regulation of T cell activation negative regulation of T cell proliferation negative regulation... |
axial cellular bud site selection bipolar cellular bud site selection cytogamy establishment of protein localization maintenance of protein location in cell positive regulation of Rho protein signal transduction regulation of establishment of cell polarity small GTPase mediated signal transduction | cell division site; cell periphery; cellular bud neck; endoplasmic reticulum; incipient cellular bud site; plasma membrane; site of polarized growth; vacuolar membrane | G protein activity GDP binding GTP binding GTPase activity | Saccharomyces cerevisiae | Cell cycle Cell division Cell membrane GTP-binding Hydrolase Lipoprotein Membrane Methylation Nucleotide-binding Prenylation Reference proteome | MRDYKLVVLG | MRDYKLVVLGAGGVGKSCLTVQFVQGVYLDTYDPTIEDSYRKTIEIDNKVFDLEILDTAGIAQFTAMRELYIKSGMGFLLVYSVTDRQSLEELMELREQVLRIKDSDRVPMVLIGNKADLINERVISVEEGIEVSSKWGRVPFYETSALLRSNVDEVFVDLVRQIIRNEMESVAVKDARNQSQQFSKIESPSTRLPSSAKQDTKQSNNKQSSKGLYNKSSQGQAKVKQSTPVNEKHKPSHAVPKSGSSNRTGISATSQQKKKKKNASTCTIL | axial cellular bud site selection bipolar cellular bud site selection cytogamy establishment of protein localization maintenance of protein location in cell positive regulation of Rho protein signal transduction regulation of establishment of cell polarity small GTPase mediated signal transduction cell division site; c... |
intracellular signal transduction negative regulation of cAMP-dependent protein kinase activity | cAMP-dependent protein kinase complex; centrosome; ciliary base; cytoplasm; cytosol; extracellular exosome; focal adhesion; membrane; nucleotide-activated protein kinase complex; plasma membrane; plasma membrane raft; protein-containing complex | cAMP binding cAMP-dependent protein kinase inhibitor activity cAMP-dependent protein kinase regulator activity protein domain specific binding protein kinase A catalytic subunit binding ubiquitin protein ligase binding | Homo sapiens | 3D-structure Acetylation Alternative splicing cAMP cAMP-binding Cell membrane Cytoplasm Membrane Nucleotide-binding Phosphoprotein Reference proteome Repeat | MSHIQIPPGL | MSHIQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARAPASVLPAATPRQSLGHPPPEPGPDRVADAKGDSESEEDEDLEVPVPSRFNRRVSVCAETYNPDEEEEDTDPRVIHPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQGDDGDNFYVIERGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYIIESGEVSILIRSRTKSNKDG... | intracellular signal transduction negative regulation of cAMP-dependent protein kinase activity cAMP-dependent protein kinase complex; centrosome; ciliary base; cytoplasm; cytosol; extracellular exosome; focal adhesion; membrane; nucleotide-activated protein kinase complex; plasma membrane; plasma membrane raft; protei... |
cell division cellular response to heat double-strand break repair via homologous recombination G2/M transition of mitotic cell cycle mitotic G2 DNA damage checkpoint signaling phosphorylation regulation of circadian rhythm rhythmic process | centrosome; cytoplasm; nucleoplasm; nucleus | ATP binding cyclin-dependent protein serine/threonine kinase activity protein serine kinase activity protein serine/threonine kinase activity RNA polymerase II CTD heptapeptide repeat kinase activity | Gallus gallus | ATP-binding Biological rhythms Cell cycle Cell division Cytoplasm Cytoskeleton Kinase Mitosis Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MEDYTKIEKI | MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELHHPNIVCLQDVLMQDARLYLIFEFLSMDLKKYLDTIPSGQYLDRSRVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGVIKLADFGLARAFGIPVRVYTHEVVTLWYRSPEVLLGSALYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNDVWPDVESLQDYKNTFPKWKPGSLGTHVQNLDEDGLDLLSKMLIYDPAKRISGKMALNHPYFDDLDKSTLPANLIKKF | cell division cellular response to heat double-strand break repair via homologous recombination G2/M transition of mitotic cell cycle mitotic G2 DNA damage checkpoint signaling phosphorylation regulation of circadian rhythm rhythmic process centrosome; cytoplasm; nucleoplasm; nucleus ATP binding cyclin-dependent protei... |
alpha-glucoside transport fucose transmembrane transport galactose transmembrane transport glucose import across plasma membrane glucose transmembrane transport intestinal D-glucose absorption intestinal hexose absorption myo-inositol transport pentose transmembrane transport renal glucose absorption response to inorga... | apical plasma membrane; brush border membrane; early endosome; extracellular exosome; intracellular organelle; intracellular vesicle; perinuclear region of cytoplasm; plasma membrane | alpha-glucoside transmembrane transporter activity D-glucose transmembrane transporter activity fucose transmembrane transporter activity galactose transmembrane transporter activity galactose:sodium symporter activity glucose transmembrane transporter activity glucose:sodium symporter activity myo-inositol:sodium symp... | Homo sapiens | 3D-structure Alternative splicing Cell membrane Disease variant Disulfide bond Glycoprotein Ion transport Membrane Phosphoprotein Reference proteome Sodium Sodium transport Sugar transport Symport Transmembrane Transmembrane helix Transport | MDSSTWSPKT | MDSSTWSPKTTAVTRPVETHELIRNAADISIIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGLAGTGAASGIAIGGFEWNALVLVVVLGWLFVPIYIKAGVVTMPEYLRKRFGGQRIQVYLSLLSLLLYIFTKISADIFSGAIFINLALGLNLYLAIFLLLAITALYTITGGLAAVIYTDTLQTVIMLVGSLILTGFAFHEVGGYDAFMEKYMKAIPTIVSDGNTTFQEKCYTPRADSFHIFRDPLTGDLPWPGFIFGMSILTLWYWCTDQVIVQRCLSAKNMSHVKGGCILCGYL... | alpha-glucoside transport fucose transmembrane transport galactose transmembrane transport glucose import across plasma membrane glucose transmembrane transport intestinal D-glucose absorption intestinal hexose absorption myo-inositol transport pentose transmembrane transport renal glucose absorption response to inorga... |
viral entry into host cell viral penetration into host nucleus | host cell endoplasmic reticulum membrane; host cell nucleus; membrane; viral capsid | DNA binding structural molecule activity | Budgerigar fledgling disease virus | Alternative initiation Alternative splicing Capsid protein DNA-binding Host endoplasmic reticulum Host membrane Host nucleus Late protein Lipoprotein Membrane Myristate Reference proteome Viral penetration into host nucleus Virion Virus entry into host cell | MGAIISAIAG | MGAIISAIAGLFELGALGGLAVDAAVNTAEIEAFIGELVLQDFSVAEIFDAIETSGIPLANTAVPVAELQQTAATSGLIGQALSAPSLIAASVKAFAGDPVAAGNNMALQVWRDQMDILFPGAEWFSNAVHNINPLAWAQSLYEQVGQSIWNYMTGNIGQAVIHQIEERTTALIVYQSRGIYDILARALETARWTLTTAAVDTYQTLKSYYGELPAVSGRVEAFRRYHEVAQGRSFFEDSDIQDVLEGKKAQKRIEGPQEMTGQTIEQQTPPGGAMQRHANDWLLPLILGLYGDLTPEWRYQLKERLNVPKRKRKLPTTS... | viral entry into host cell viral penetration into host nucleus host cell endoplasmic reticulum membrane; host cell nucleus; membrane; viral capsid DNA binding structural molecule activity Budgerigar fledgling disease virus Alternative initiation Alternative splicing Capsid protein DNA-binding Host endoplasmic reticulu... |
blood coagulation endosomal transport endosome organization negative regulation of phospholipase A2 activity negative regulation of serine-type endopeptidase activity | collagen-containing extracellular matrix; cytoplasm; cytosol; late endosome membrane; plasma membrane; sarcolemma | actin filament binding calcium ion binding calcium-dependent phospholipid binding phosphatidylinositol-3,4,5-trisphosphate binding phosphatidylinositol-3,4-bisphosphate binding phosphatidylinositol-4,5-bisphosphate binding | Homo sapiens | 3D-structure Alternative splicing Annexin Blood coagulation Calcium Calcium/phospholipid-binding Hemostasis Metal-binding Reference proteome Repeat | MAWWKSWIEQ | MAWWKSWIEQEGVTVKSSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTETLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMKAYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPGLALQDAQDLYAAGEKIRGTDEMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMIMEDTSGDYKNALL... | blood coagulation endosomal transport endosome organization negative regulation of phospholipase A2 activity negative regulation of serine-type endopeptidase activity collagen-containing extracellular matrix; cytoplasm; cytosol; late endosome membrane; plasma membrane; sarcolemma actin filament binding calcium ion bind... |
canonical glycolysis gluconeogenesis glycolytic process | cytosol; extracellular exosome; extracellular space; membrane; phosphopyruvate hydratase complex; plasma membrane | magnesium ion binding phosphopyruvate hydratase activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Cytoplasm Disease variant Glycogen storage disease Glycolysis Lyase Magnesium Metal-binding Phosphoprotein Reference proteome | MAMQKIFARE | MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKGRYLGKGVLKAVENINNTLGPALLQKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNPDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKVVIGMDVAASEFYRNGKYDLDFKSPDDPARHITGEKLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVNIQIVGDDL... | canonical glycolysis gluconeogenesis glycolytic process cytosol; extracellular exosome; extracellular space; membrane; phosphopyruvate hydratase complex; plasma membrane magnesium ion binding phosphopyruvate hydratase activity Homo sapiens 3D-structure Acetylation Alternative splicing Cytoplasm Disease variant Glycogen... |
cellular response to UV-A collagen catabolic process proteolysis | extracellular matrix; extracellular region | metalloendopeptidase activity peptidase activity zinc ion binding | Oryctolagus cuniculus | Calcium Collagen degradation Disulfide bond Extracellular matrix Glycoprotein Hydrolase Metal-binding Metalloprotease Phosphoprotein Protease Reference proteome Repeat Secreted Signal Zinc Zymogen | MPGLPLLLLL | MPGLPLLLLLLWGVGSHGFPAASETQEQDVEMVQKYLENYYNLKDDWRKIPKQRGNGLAVEKLKQMQEFFGLKVTGKPDAETLKMMKQPRCGVPDVAQFVLTPGNPRWEQTHLTYRIENYTPDLSRADVDNAIEKAFQLWSNVTPLTFTKVSKGQADIMISFVRGDHRDNSPFDGPEGQLAHAFQPGLGIGGDVHFDEDDRWTKDFRNYNLYRVAAHELGHSLGLSHSTDIGALMYPNYMFSGDVQLAQDDIDGIQAIYGPSQNPSQPVGPQTPKVCDSKLTFDAITTIRGEIMFFKDRFYMRANPYYSEVELNFISVFW... | cellular response to UV-A collagen catabolic process proteolysis extracellular matrix; extracellular region metalloendopeptidase activity peptidase activity zinc ion binding Oryctolagus cuniculus Calcium Collagen degradation Disulfide bond Extracellular matrix Glycoprotein Hydrolase Metal-binding Metalloprotease Phosph... |
activation of adenylate cyclase activity adenylate cyclase-activating adrenergic receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway brown fat cell differentiation carbohydrate metabolic process diet induced thermogenesis eating behavior energy reserve metabolic process ... | plasma membrane; receptor complex | beta-3 adrenergic receptor binding beta-adrenergic receptor activity beta3-adrenergic receptor activity epinephrine binding norepinephrine binding protein homodimerization activity | Homo sapiens | Cell membrane Diabetes mellitus Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Obesity Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MAPWPHENSS | MAPWPHENSSLAPWPDLPTLAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIVAIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLCVTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMSQWWRVGADAEAQRCHSNPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRGELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGTFTLCWLPFFLANVLRALGGP... | activation of adenylate cyclase activity adenylate cyclase-activating adrenergic receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway brown fat cell differentiation carbohydrate metabolic process diet induced thermogenesis eating behavior energy reserve metabolic process ... |
positive regulation of transcription by RNA polymerase II transcription by RNA polymerase II transcription elongation by RNA polymerase II transcription initiation at RNA polymerase II promoter | microtubule cytoskeleton; nucleoplasm; nucleus; transcription factor TFIIF complex | DNA binding RNA polymerase II general transcription initiation factor activity | Homo sapiens | 3D-structure Acetylation Direct protein sequencing DNA-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MAERGELDLT | MAERGELDLTGAKQNTGVWLVKVPKYLSQQWAKASGRGEVGKLRIAKTQGRTEVSFTLNEDLANIHDIGGKPASVSAPREHPFVLQSVGGQTLTVFTESSSDKLSLEGIVVQRAECRPAASENYMRLKRLQIEESSKPVRLSQQLDKVVTTNYKPVANHQYNIEYERKKKEDGKRARADKQHVLDMLFSAFEKHQYYNLKDLVDITKQPVVYLKEILKEIGVQNVKGIHKNTWELKPEYRHYQGEEKSD | positive regulation of transcription by RNA polymerase II transcription by RNA polymerase II transcription elongation by RNA polymerase II transcription initiation at RNA polymerase II promoter microtubule cytoskeleton; nucleoplasm; nucleus; transcription factor TFIIF complex DNA binding RNA polymerase II general trans... |
blood coagulation cell surface receptor signaling pathway negative regulation of activation of membrane attack complex regulation of complement activation regulation of complement-dependent cytotoxicity | cell surface; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment membrane; ER to Golgi transport vesicle membrane; external side of plasma membrane; extracellular exosome; extracellular space; focal adhesion; Golgi membrane; membrane; plasma membrane; specific granule membrane; tertiar... | complement binding | Homo sapiens | 3D-structure Alternative splicing Cell membrane Direct protein sequencing Disease variant Disulfide bond Glycation Glycoprotein GPI-anchor Hereditary hemolytic anemia Lipoprotein Membrane Reference proteome Secreted Signal | MGIQGGSVLF | MGIQGGSVLFGLLLVLAVFCHSGHSLQCYNCPNPTADCKTAVNCSSDFDACLITKAGLQVYNKCWKFEHCNFNDVTTRLRENELTYYCCKKDLCNFNEQLENGGTSLSEKTVLLLVTPFLAAAWSLHP | blood coagulation cell surface receptor signaling pathway negative regulation of activation of membrane attack complex regulation of complement activation regulation of complement-dependent cytotoxicity cell surface; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment membrane; ER to Go... |
DNA transposition | chromosome | DNA binding endonuclease activity metal ion binding transposase activity | Escherichia coli | 3D-structure DNA recombination DNA-binding Endonuclease Hydrolase Magnesium Manganese Metal-binding Nuclease Plasmid Transposable element Transposition | MAKANSSFSE | MAKANSSFSEVQIARRIKEGRGQGHGKDYIPWLTVQEVPSSGRSHRIYSHKTGRVHHLLSDLELAVFLSLEWESSVLDIREQFPLLPSDTRQIAIDSGIKHPVIRGVDQVMSTDFLVDCKDGPFEQFAIQVKPAAALQDERTLEKLELERRYWQQKQIPWFIFTDKEINPVVKENIEWLYSVKTEEVSAELLAQLSPLAHILQEKGDENIINVCKQVDIAYDLELGKTLSEIRALTANGFIKFNIYKSFRANKCADLCISQVVNMEELRYVAN | DNA transposition chromosome DNA binding endonuclease activity metal ion binding transposase activity Escherichia coli3D-structure DNA recombination DNA-binding Endonuclease Hydrolase Magnesium Manganese Metal-binding Nuclease Plasmid Transposable element Transposition MAKANSSFSE MAKANSSFSEVQIARRIKEGRGQGHGKDYIPWLTVQEVP... |
folic acid metabolic process tetrahydrofolate interconversion tetrahydrofolate metabolic process | extracellular space; mitochondrial matrix; mitochondrion | magnesium ion binding methenyltetrahydrofolate cyclohydrolase activity methylenetetrahydrofolate dehydrogenase (NAD+) activity methylenetetrahydrofolate dehydrogenase (NADP+) activity phosphate ion binding | Homo sapiens | 3D-structure Acetylation Alternative splicing Hydrolase Isopeptide bond Magnesium Mitochondrion Multifunctional enzyme NAD NADP One-carbon metabolism Oxidoreductase Reference proteome Transit peptide Ubl conjugation | MAATSLMSAL | MAATSLMSALAARLLQPAHSCSLRLRPFHLAAVRNEAVVISGRKLAQQIKQEVRQEVEEWVASGNKRPHLSVILVGENPASHSYVLNKTRAAAVVGINSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLPLPEHIDERRICNAVSPDKDVDGFHVINVGRMCLDQYSMLPATPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTISHRYTPKEQLKKHTILADIVISAAGIPNLITADMIKEGAAVIDVGINRVHDPVTAKPKLVGDVDFEGVRQKAGYITPVPGGVGPMTVAML... | folic acid metabolic process tetrahydrofolate interconversion tetrahydrofolate metabolic process extracellular space; mitochondrial matrix; mitochondrion magnesium ion binding methenyltetrahydrofolate cyclohydrolase activity methylenetetrahydrofolate dehydrogenase (NAD+) activity methylenetetrahydrofolate dehydrogenase... |
anterior/posterior pattern specification cell morphogenesis membrane organization negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II nervous system development open tracheal system development periodic partitioning by pair rule gene posterior head segmentation r... | nucleus | DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific E-box binding protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding transcription corepressor binding | Drosophila melanogaster | Developmental protein DNA-binding Nucleus Pair-rule protein Reference proteome Repressor Transcription Transcription regulation Ubl conjugation | MVTGVTAANM | MVTGVTAANMTNVLGTAVVPAQLKETPLKSDRRSNKPIMEKRRRARINNCLNELKTLILDATKKDPARHSKLEKADILEKTVKHLQELQRQQAAMQQAADPKIVNKFKAGFADCVNEVSRFPGIEPAQRRRLLQHLSNCINGVKTELHQQQRQQQQQSIHAQMLPSPPSSPEQDSQQGAAAPYLFGIQQTASGYFLPNGMQVIPTKLPNGSIALVLPQSLPQQQQQQLLQHQQQQQQLAVAAAAAAAAAAQQQPMLVSMPQRTASTGSASSHSSAGYESAPGSSSSCSYAPPSPANSSYEPMDIKPSVIQRVPMEQQPLS... | anterior/posterior pattern specification cell morphogenesis membrane organization negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II nervous system development open tracheal system development periodic partitioning by pair rule gene posterior head segmentation r... |
dolichol metabolic process dolichol-linked oligosaccharide biosynthetic process GPI anchor biosynthetic process protein O-linked mannosylation | cell periphery; endoplasmic reticulum; endoplasmic reticulum membrane; mitochondrial outer membrane; mitochondrion; nuclear outer membrane-endoplasmic reticulum membrane network | dolichyl-phosphate beta-D-mannosyltransferase activity metal ion binding | Saccharomyces cerevisiae | Acetylation Direct protein sequencing Endoplasmic reticulum Glycosyltransferase Magnesium Manganese Membrane Metal-binding Phosphoprotein Reference proteome Transferase Transmembrane Transmembrane helix | MSIEYSVIVP | MSIEYSVIVPAYHEKLNIKPLTTRLFAGMSPEMAKKTELIFVDDNSQDGSVEEVDALAHQGYNVRIIVRTNERGLSSAVLKGFYEAKGQYLVCMDADLQHPPETVPKLFESLHDHAFTLGTRYAPGVGIDKDWPMYRRVISSTARMMARPLTIASDPMSGFFGLQKKYLENCNPRDINSQGFKIALELLAKLPLPRDPRVAIGEVPFTFGVRTEGESKLSGKVIIQYLQQLKELYVFKFGANNLILFITFWSILFFYVCYQLYHLVF | dolichol metabolic process dolichol-linked oligosaccharide biosynthetic process GPI anchor biosynthetic process protein O-linked mannosylation cell periphery; endoplasmic reticulum; endoplasmic reticulum membrane; mitochondrial outer membrane; mitochondrion; nuclear outer membrane-endoplasmic reticulum membrane network... |
intracellular signal transduction MAPK cascade negative regulation of apoptotic process phosphorylation positive regulation of peptidyl-serine phosphorylation regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of TOR signaling | cytosol; mitochondrion | ATP binding MAP kinase kinase kinase activity metal ion binding protein serine kinase activity protein serine/threonine kinase activity | Rattus norvegicus | ATP-binding Kinase Metal-binding Nucleotide-binding Phosphoprotein Proto-oncogene Reference proteome Serine/threonine-protein kinase Transferase Zinc Zinc-finger | MEPPRGPPAS | MEPPRGPPASGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCVVYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRRQFYHSIQDLSGGSRQQEVPSNLSVNELLTPQGPSPFTQQRDQEHFSFPAPANPPLQRIRSTSTPNVHMVSTTAPMDSSLMQFTAQSFSTDAAGRGGDGAPRGSPSPASVSSGRKSPHSKLPAEQRERKSLADEKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFG... | intracellular signal transduction MAPK cascade negative regulation of apoptotic process phosphorylation positive regulation of peptidyl-serine phosphorylation regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of TOR signaling cytosol; mitochondrion ATP binding MAP kinase kinase kinase a... |
androgen biosynthetic process C21-steroid hormone metabolic process estrogen biosynthetic process hippocampus development response to corticosterone steroid biosynthetic process | cytoplasm; endoplasmic reticulum; endoplasmic reticulum membrane; intercellular bridge; intracellular membrane-bounded organelle; mitochondrial inner membrane; mitochondrial intermembrane space; nucleolus; smooth endoplasmic reticulum membrane | 3-beta-hydroxy-delta5-steroid dehydrogenase activity 3-keto sterol reductase activity 5alpha-androstane-3beta,17beta-diol dehydrogenase activity cholesterol dehydrogenase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor steroid delta-isomerase activity | Homo sapiens | Direct protein sequencing Endoplasmic reticulum Isomerase Lipid metabolism Membrane Mitochondrion Multifunctional enzyme NAD NADP Oxidoreductase Reference proteome Steroid metabolism Steroidogenesis Transmembrane Transmembrane helix | MTGWSCLVTG | MTGWSCLVTGAGGFLGQRIIRLLVKEKELKEIRVLDKAFGPELREEFSKLQNKTKLTVLEGDILDEPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPAPYPHSKKLAEKAVLAANGWNLKNGGTLYTCALRPMYIYGEGSRFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRALQDPKKAPSIRGQFYYISDDTPHQSYDNLNYTLSKEFGLRLDSRWSFPLSLMYWIGFLLEIVSFLLRPIYTYRPPFNRHIV... | androgen biosynthetic process C21-steroid hormone metabolic process estrogen biosynthetic process hippocampus development response to corticosterone steroid biosynthetic process cytoplasm; endoplasmic reticulum; endoplasmic reticulum membrane; intercellular bridge; intracellular membrane-bounded organelle; mitochondria... |
adipose tissue development bone development cellular response to metal ion estrogen biosynthetic process estrogen metabolic process gene expression lysosome organization skeletal muscle tissue development steroid biosynthetic process testosterone biosynthetic process | cytoplasm; cytosol | 17-beta-hydroxysteroid dehydrogenase (NADP+) activity catalytic activity dihydrotestosterone 17-beta-dehydrogenase activity estradiol 17-beta-dehydrogenase activity estradiol binding NADP binding NADP+ binding protein homodimerization activity small molecule binding steroid binding testosterone 17-beta-dehydrogenase (... | Homo sapiens | 3D-structure Cytoplasm Direct protein sequencing Lipid biosynthesis Lipid metabolism NADP Oxidoreductase Phosphoprotein Reference proteome Steroid biosynthesis | MARTVVLITG | MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEVFLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHREVFGDVPAKAEAGAEAGGGAGPGAEDEAGRGAVGDPEL... | adipose tissue development bone development cellular response to metal ion estrogen biosynthetic process estrogen metabolic process gene expression lysosome organization skeletal muscle tissue development steroid biosynthetic process testosterone biosynthetic process cytoplasm; cytosol 17-beta-hydroxysteroid dehydrogen... |
carbon catabolite activation of transcription from RNA polymerase II promoter regulation of carbohydrate metabolic process regulation of cellular respiration regulation of DNA-templated transcription | CCAAT-binding factor complex; mitochondrial respirasome | DNA binding RNA polymerase II-specific DNA-binding transcription factor binding transcription coactivator activity | Saccharomyces cerevisiae | Activator DNA-binding Nucleus Reference proteome Transcription Transcription regulation | MTAKTFLLQA | MTAKTFLLQASASRPRSNHFKNEHNNIPLAPVPIAPNTNHHNNSSLEFENDGSKKKKKSSLVVRTSKHWVLPPRPRPGRRSSSHNTLPANNTNNILNVGPNSRNSSNNNNNNNIISNRKQASKEKRKIPRHIQTIDEKLINDSNYLAFLKFDDLENEKFHSSASSISSPSYSSPSFSSYRNRKKSEFMDDESCTDVETIAAHNSLLTKNHHIDSSSNVHAPPTKKSKLNDFDLLSLSSTSSSATPVPQLTKDLNMNLNFHKIPHKASFPDSPADFSPADSVSLIRNHSLPTNLQVKDKIEDLNEIKFFNDFEKLEFFNKY... | carbon catabolite activation of transcription from RNA polymerase II promoter regulation of carbohydrate metabolic process regulation of cellular respiration regulation of DNA-templated transcription CCAAT-binding factor complex; mitochondrial respirasome DNA binding RNA polymerase II-specific DNA-binding transcription... |
arabinose catabolic process cellular response to oxidative stress D-xylose catabolic process glycerol to glycerone phosphate metabolic process | cytoplasm; cytosol; nucleus | alditol:NADP+ 1-oxidoreductase activity aldo-keto reductase (NADP) activity glycerol 2-dehydrogenase (NADP+) activity glycerol dehydrogenase activity mRNA binding oxidoreductase activity | Saccharomyces cerevisiae | Cytoplasm Glycerol metabolism NADP Oxidoreductase Phosphoprotein Reference proteome | MPATLHDSTK | MPATLHDSTKILSLNTGAQIPQIGLGTWQSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQAIKDSGVPREEIFVTTKLWCTQHHEPEVALDQSLKRLGLDYVDLYLMHWPARLDPAYIKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLKDLLASQGNKLTPAANQVEIHPLLPQDELINFCKSKGIVVEAYSPLGSTDAPLLKEPVILEIAKKNNVQPGHVVISWHVQRGYVVLPKSVNPDRIKTNRKIFTLSTEDFEAINNISKEKGEKRVVHPNWSPFEVFK | arabinose catabolic process cellular response to oxidative stress D-xylose catabolic process glycerol to glycerone phosphate metabolic process cytoplasm; cytosol; nucleus alditol:NADP+ 1-oxidoreductase activity aldo-keto reductase (NADP) activity glycerol 2-dehydrogenase (NADP+) activity glycerol dehydrogenase activit... |
proteolysis suppression by virus of host gene expression | viral nucleocapsid | aspartic-type endopeptidase activity nucleic acid binding structural molecule activity zinc ion binding | Human T-cell leukemia virus 1 | Aspartyl protease Capsid protein Eukaryotic host gene expression shutoff by virus Eukaryotic host translation shutoff by virus Host gene expression shutoff by virus Host-virus interaction Hydrolase Lipoprotein Metal-binding Myristate Phosphoprotein Protease Reference proteome Repeat Ribosomal frameshifting Viral nucleo... | MGQIFSRSAS | MGQIFSRSASPIPRPPRGLAAHHWLNFLQAAYRLEPGPSSYDFHQLKKFLKIALETPVWICPINYSLLASLLPKGYPGRVNEILHILIQTQAQIPSRPAPPPPSSSTHDPPDSDPQIPPPYVEPTAPQVLPVMHPHGAPPNHRPWQMKDLQAIKQEVSQAAPGSPQFMQTIRLAVQQFDPTAKDLQDLLQYLCSSLVASLHHQQLDSLISEAETRGITGYNPLAGPLRVQANNPQQQGLRREYQQLWLAAFAALPGSAKDPSWASILQGLEEPYHAFVERLNIALDNGLPEGTPKDPILRSLAYSNANKECQKLLQARGH... | proteolysis suppression by virus of host gene expression viral nucleocapsid aspartic-type endopeptidase activity nucleic acid binding structural molecule activity zinc ion binding Human T-cell leukemia virus 1 Aspartyl protease Capsid protein Eukaryotic host gene expression shutoff by virus Eukaryotic host translation... |
viral process | viral nucleocapsid | nucleic acid binding structural molecule activity zinc ion binding | Human T-cell leukemia virus 1 | Capsid protein Disulfide bond Host-virus interaction Lipoprotein Metal-binding Myristate Phosphoprotein Reference proteome Repeat Ribosomal frameshifting Ubl conjugation Viral nucleoprotein Virion Zinc Zinc-finger | MGQIFSRSAS | MGQIFSRSASPIPRPPRGLAAHHWLNFLQAAYRLEPGPSSYDFHQLKKFLKIALETPVWICPINYSLLASLLPKGYPGRVNEILHILIQTQAQIPSRPAPPPPSSSTHDPPDSDPQIPPPYVEPTAPQVLPVMHPHGAPPNHRPWQMKDLQAIKQEVSQAAPGSPQFMQTIRLAVQQFDPTAKDLQDLLQYLCSSLVASLHHQQLDSLISEAETRGITGYNPLAGPLRVQANNPQQQGLRREYQQLWLAAFAALPGSAKDPSWASILQGLEEPYHAFVERLNIALDNGLPEGTPKDPILRSLAYSNANKECQKLLQARGH... | viral process viral nucleocapsid nucleic acid binding structural molecule activity zinc ion binding Human T-cell leukemia virus 1 Capsid protein Disulfide bond Host-virus interaction Lipoprotein Metal-binding Myristate Phosphoprotein Reference proteome Repeat Ribosomal frameshifting Ubl conjugation Viral nucleoprotein... |
viral process | viral nucleocapsid | nucleic acid binding structural molecule activity zinc ion binding | Human T-cell leukemia virus 1 | 3D-structure Capsid protein Disulfide bond Host-virus interaction Lipoprotein Metal-binding Myristate Phosphoprotein Repeat Ribosomal frameshifting Ubl conjugation Viral nucleoprotein Virion Zinc Zinc-finger | MGQIFSRSAS | MGQIFSRSASPIPRPPRGLAAHHWLNFLQAAYRLEPGPSSYDFHQLKKFLKIALETPVWICPINYSLLASLLPKGYPGRVNEILHILIQTQAQIPSRPAPPPPSSPTHDPPDSDPQIPPPYVEPTAPQVLPVMHPHGAPPNHRPWQMKDLQAIKQEVSQAAPGSPQFMQTIRLAVQQFDPTAKDLQDLLQYLCSSLVASLHHQQLDSLISEAETRGITSYNPLAGPLRVQANNPQQQGLRREYQQLWLAAFAALPGSAKDPSWASILQGLEEPYHAFVERLNIALDNGLPEGTPKDPILRSLAYSNANKECQKLLQARGH... | viral process viral nucleocapsid nucleic acid binding structural molecule activity zinc ion binding Human T-cell leukemia virus 1 3D-structure Capsid protein Disulfide bond Host-virus interaction Lipoprotein Metal-binding Myristate Phosphoprotein Repeat Ribosomal frameshifting Ubl conjugation Viral nucleoprotein Virio... |
cellular response to lipopolysaccharide induction by virus of host NF-kappaB cascade negative regulation of gene expression perturbation by virus of host G0/G1 transition checkpoint perturbation by virus of host G1/S transition checkpoint peturbation by virus of host exit from mitosis positive regulation of DNA-templat... | host cell cytoplasm; host cell nucleus | DNA binding metal ion binding SH3 domain binding | Human T-cell leukemia virus 1 | 3D-structure Activation of host NF-kappa-B by virus Activator DNA-binding G0/G1 host cell cycle checkpoint dysregulation by virus G1/S host cell cycle checkpoint dysregulation by virus Host cytoplasm Host nucleus Host-virus interaction Inhibition of host mitotic exit by virus Metal-binding Modulation of host cell cycle... | MAHFPGFGQS | MAHFPGFGQSLLFGYPVYVFGDCVQGDWCPISGGLCSARLHRHALLATCPEHQITWDPIDGRVIGSALQFLIPRLPSFPTQRTSKTLKVLTPPITHTTPNIPPSFLQAMRKYSPFRNGYMEPTLGQHLPTLSFPDPGLRPQNLYTLWGGSVVCMYLYQLSPPITWPLLPHVIFCHPGQLGAFLTNVPYKRIEKLLYKISLTTGALIILPEDCLPTTLFQPARAPVTLTAWQNGLLPFHSTLTTPGLIWTFTDGTPMISGPCPKDGQPSLVLQSSSFIFHKFQTKAYHPSFLLSHGLIQYSSFHNLHLLFEEYTNIPISLL... | cellular response to lipopolysaccharide induction by virus of host NF-kappaB cascade negative regulation of gene expression perturbation by virus of host G0/G1 transition checkpoint perturbation by virus of host G1/S transition checkpoint peturbation by virus of host exit from mitosis positive regulation of DNA-templat... |
selenocysteine incorporation selenocysteine metabolic process | cytoplasm | GDP binding GTP binding GTPase activity selenocysteine insertion sequence binding translation elongation factor activity tRNA binding | Escherichia coli | 3D-structure Cytoplasm GTP-binding Nucleotide-binding Protein biosynthesis Reference proteome | MIIATAGHVD | MIIATAGHVDHGKTTLLQAITGVNADRLPEEKKRGMTIDLGYAYWPQPDGRVPGFIDVPGHEKFLSNMLAGVGGIDHALLVVACDDGVMAQTREHLAILQLTGNPMLTVALTKADRVDEARVDEVERQVKEVLREYGFAEAKLFITAATEGRGMDALREHLLQLPEREHASQHSFRLAIDRAFTVKGAGLVVTGTALSGEVKVGDSLWLTGVNKPMRVRALHAQNQPTETANAGQRIALNIAGDAEKEQINRGDWLLADVPPEPFTRVIVELQTHTPLTQWQPLHIHHAASHVTGRVSLLEDNLAELVFDTPLWLADNDR... | selenocysteine incorporation selenocysteine metabolic process cytoplasm GDP binding GTP binding GTPase activity selenocysteine insertion sequence binding translation elongation factor activity tRNA binding Escherichia coli 3D-structure Cytoplasm GTP-binding Nucleotide-binding Protein biosynthesis Reference proteome MII... |
memory modulation of chemical synaptic transmission negative regulation of neuron apoptotic process nerve development nerve growth factor signaling pathway neuron projection morphogenesis peripheral nervous system development positive regulation of collateral sprouting positive regulation of peptidyl-serine phosphoryla... | axon; cytoplasm; dendrite; extracellular space; perinuclear region of cytoplasm; synaptic vesicle | growth factor activity nerve growth factor receptor binding | Sus scrofa | Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Glycoprotein Growth factor Reference proteome Secreted Signal | MTILFLTMVI | MTILFLTMVISYFGCMKAAPMKEANVRGQGSLAYPGVRTHGTLESVNGPKAGSRGLTSSSSSSLADTFEHVIEELLDEDQKVRPNEENNKDADMYTSRVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSDPARRGELSVCDSISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR | memory modulation of chemical synaptic transmission negative regulation of neuron apoptotic process nerve development nerve growth factor signaling pathway neuron projection morphogenesis peripheral nervous system development positive regulation of collateral sprouting positive regulation of peptidyl-serine phosphoryla... |
actin cytoskeleton organization adaptive immune response cellular response to glucocorticoid stimulus G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger granulocyte chemotaxis inflammatory response innate immune response monocyte chemotaxis negative regulation of exocytosis nega... | apical plasma membrane; basolateral plasma membrane; cytoplasm; early endosome membrane; extracellular exosome; extracellular space; lateral plasma membrane; motile cilium; nucleus; phagocytic cup; plasma membrane | calcium ion binding calcium-dependent phospholipid binding phospholipase A2 inhibitor activity | Cavia cutleri | Acetylation Adaptive immunity Annexin Calcium Calcium/phospholipid-binding Cell membrane Cell projection Cilium Cytoplasm Cytoplasmic vesicle Direct protein sequencing Disulfide bond Endosome Immunity Inflammatory response Innate immunity Isopeptide bond Membrane Metal-binding Nucleus Phospholipase A2 inhibitor Phospho... | MSMVSEFLKQ | MSMVSEFLKQAYFIDNQEQDYVKTVKSSKGGPGSAVSPYPSFDASSDVAALHKAITVKGVDEATIIDILTKRNNAQRQQIKAAYLQEKGKPLDEALKKALTGHLEEVVLALLKTPAQLDADELRAAMKGLGTDEDTLIEILVSRKNREIKEINRVYRDELKRDLAKDITSDTSGDFQKALLSLAKGDRCEDLSVNDDLADSDARALYEAGERRKGTDVNVFITILTTRSYSHLRRVFQKYTKYSQHDMNKALDLELKGDIENCLTAIVKCATSTPAFFAEKLHLAMKGAGTRHKALIRIMVSRSEIDMNDIKVYYQKMYG... | actin cytoskeleton organization adaptive immune response cellular response to glucocorticoid stimulus G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger granulocyte chemotaxis inflammatory response innate immune response monocyte chemotaxis negative regulation of exocytosis nega... |
antigen processing and presentation of exogenous peptide antigen via MHC class II protein autoprocessing proteolysis | endosome; intracellular membrane-bounded organelle | aspartic-type endopeptidase activity identical protein binding peptidase activity | Homo sapiens | 3D-structure Alternative splicing Aspartyl protease Autocatalytic cleavage Direct protein sequencing Disulfide bond Endosome Glycoprotein Hydrolase Protease Reference proteome Signal Zymogen | MKTLLLLLLV | MKTLLLLLLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAPVDGEYAVECANLNVM... | antigen processing and presentation of exogenous peptide antigen via MHC class II protein autoprocessing proteolysis endosome; intracellular membrane-bounded organelle aspartic-type endopeptidase activity identical protein binding peptidase activity Homo sapiens 3D-structure Alternative splicing Aspartyl protease Autoc... |
antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to interleukin-17 cellular response to lipopolysaccharide chemokine-mediated signaling pathway inflammatory response neutrophil chemotaxis positive regulation of cytosolic calcium ion concentration positive regulation of hematopoi... | extracellular space | chemokine activity CXCR chemokine receptor binding growth factor activity | Rattus norvegicus | Cytokine Direct protein sequencing Disulfide bond Growth factor Inflammatory response Reference proteome Secreted Signal | MVSATRSLLC | MVSATRSLLCAALPVLATSRQATGAPVANELRCQCLQTVAGIHFKNIQSLKVMPPGPHCTQTEVIATLKNGREACLDPEAPMVQKIVQKMLKGVPK | antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to interleukin-17 cellular response to lipopolysaccharide chemokine-mediated signaling pathway inflammatory response neutrophil chemotaxis positive regulation of cytosolic calcium ion concentration positive regulation of hematopoi... |
cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to type II interferon cellular response to xenobiotic stimulus chemokine-mediated signaling pathway eosinophil chemotaxis G protein-coupled receptor signaling pathway inflammatory response leukocyte chemotaxis lymphocyte che... | extracellular space | CCR chemokine receptor binding CCR1 chemokine receptor binding CCR5 chemokine receptor binding chemokine activity identical protein binding | Mus musculus | Chemotaxis Cytokine Disulfide bond Inflammatory response Reference proteome Secreted Signal | MKLCVSALSL | MKLCVSALSLLLLVAAFCAPGFSAPMGSDPPTSCCFSYTSRQLHRSFVMDYYETSSLCSKPAVVFLTKRGRQICANPSEPWVTEYMSDLELN | cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to type II interferon cellular response to xenobiotic stimulus chemokine-mediated signaling pathway eosinophil chemotaxis G protein-coupled receptor signaling pathway inflammatory response leukocyte chemotaxis lymphocyte che... |
cAMP-mediated signaling cellular response to cGMP cellular response to granulocyte macrophage colony-stimulating factor stimulus cellular response to macrophage colony-stimulating factor stimulus cellular response to mechanical stimulus cGMP catabolic process cGMP-mediated signaling establishment of endothelial barrier... | cytoplasm; cytosol; endoplasmic reticulum; Golgi apparatus; mitochondrial inner membrane; mitochondrial matrix; mitochondrial outer membrane; nucleus; perinuclear region of cytoplasm; plasma membrane; presynaptic membrane; synaptic membrane | 3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-GMP phosphodiesterase activity cGMP binding cGMP-stimulated cyclic-nucleotide phosphodiesterase activity metal ion binding protein homodimerization activity | Bos taurus | 3D-structure Acetylation Alternative splicing cAMP Cell membrane cGMP cGMP-binding Cytoplasm Direct protein sequencing Hydrolase Magnesium Membrane Metal-binding Mitochondrion Mitochondrion inner membrane Mitochondrion outer membrane Nucleotide-binding Reference proteome Repeat Zinc | MRRQPAASRD | MRRQPAASRDLFAQEPVPPGSGDGALQDALLSLGSVIDVAGLQQAVKEALSAVLPKVETVYTYLLDGESRLVCEEPPHELPQEGKVREAVISRKRLGCNGLGPSDLPGKPLARLVAPLAPDTQVLVIPLVDKEAGAVAAVILVHCGQLSDNEEWSLQAVEKHTLVALKRVQALQQRESSVAPEATQNPPEEAAGDQKGGVAYTNQDRKILQLCGELYDLDASSLQLKVLQYLQQETQASRCCLLLVSEDNLQLSCKVIGDKVLEEEISFPLTTGRLGQVVEDKKSIQLKDLTSEDMQQLQSMLGCEVQAMLCVPVISRAT... | cAMP-mediated signaling cellular response to cGMP cellular response to granulocyte macrophage colony-stimulating factor stimulus cellular response to macrophage colony-stimulating factor stimulus cellular response to mechanical stimulus cGMP catabolic process cGMP-mediated signaling establishment of endothelial barrier... |
signal transduction | neuronal cell body | 3',5'-cyclic-GMP phosphodiesterase activity calmodulin binding calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity metal ion binding | Bos taurus | Alternative splicing Calmodulin-binding cAMP cGMP Direct protein sequencing Hydrolase Magnesium Metal-binding Reference proteome Zinc | MGSTATETEE | MGSTATETEELENTTFKYLIGEQTEKMWQRLKGILRCLVKQLEKGDVNVIDLKKNIEYAASVLEAVYIDETRRLLDTDDELSDIQSDSVPSEVRDWLASTFTRKMGMMKKKSEEKPRFRSIVHVVQAGIFVERMYRKSYHMVGLAYPEAVIVTLKDVDKWSFDVFALNEASGEHSLKFMIYELFTRYDLINRFKIPVSCLIAFAEALEVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGIMHWLTELEILAMVFAAAIHDYEHTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLMQEEEMNVLINLSKDDWRDLR... | signal transduction neuronal cell body 3',5'-cyclic-GMP phosphodiesterase activity calmodulin binding calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity metal ion binding Bos taurus Alternative splicing Cal... |
complement activation, classical pathway innate immune response inner ear development synapse pruning | collagen trimer; complement component C1 complex; complement component C1q complex; extracellular region; extracellular space; postsynapse; synapse | identical protein binding | Mus musculus | Collagen Complement pathway Disulfide bond Glycoprotein Hydroxylation Immunity Innate immunity Pyrrolidone carboxylic acid Reference proteome Repeat Secreted Signal | MKTQWGEVWT | MKTQWGEVWTHLLLLLLGFLHVSWAQSSCTGPPGIPGIPGVPGVPGSDGQPGTPGIKGEKGLPGLAGDLGEFGEKGDPGIPGTPGKVGPKGPVGPKGTPGPSGPRGPKGDSGDYGATQKVAFSALRTINSPLRPNQVIRFEKVITNANENYEPRNGKFTCKVPGLYYFTYHASSRGNLCVNLVRGRDRDSMQKVVTFCDYAQNTFQVTTGGVVLKLEQEEVVHLQATDKNSLLGIEGANSIFTGFLLFPDMDA | complement activation, classical pathway innate immune response inner ear development synapse pruning collagen trimer; complement component C1 complex; complement component C1q complex; extracellular region; extracellular space; postsynapse; synapse identical protein binding Mus musculus Collagen Complement pathway Dis... |
cytoplasmic translation translation translation at postsynapse translation at presynapse | cytoplasm; cytosol; cytosolic large ribosomal subunit; cytosolic ribosome; endoplasmic reticulum; postsynapse; presynapse; ribosome; synapse | structural constituent of ribosome | Mus musculus | 3D-structure Acetylation Cytoplasm Hydroxylation Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein | MPSRLRKTRK | MPSRLRKTRKLRGHVSHGHGRIGKHRKHPGGRGNAGGMHHHRINFDKYHPGYFGKVGMRHYHLKRNQSFCPTVNLDKLWTLVSEQTRVNAAKNKTGVAPIIDVVRSGYYKVLGKGKLPKQPVIVKAKFFSRRAEEKIKGVGGACVLVA | cytoplasmic translation translation translation at postsynapse translation at presynapse cytoplasm; cytosol; cytosolic large ribosomal subunit; cytosolic ribosome; endoplasmic reticulum; postsynapse; presynapse; ribosome; synapse structural constituent of ribosome Mus musculus 3D-structure Acetylation Cytoplasm Hydroxy... |
cytoplasmic translation negative regulation of mRNA splicing, via spliceosome rRNA processing | cytoplasm; cytosol; cytosolic large ribosomal subunit | pre-mRNA 5'-splice site binding RNA binding structural constituent of ribosome | Saccharomyces cerevisiae | 3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation | MAPVKSQESI | MAPVKSQESINQKLALVIKSGKYTLGYKSTVKSLRQGKSKLIIIAANTPVLRKSELEYYAMLSKTKVYYFQGGNNELGTAVGKLFRVGVVSILEAGDSDILTTLA | cytoplasmic translation negative regulation of mRNA splicing, via spliceosome rRNA processing cytoplasm; cytosol; cytosolic large ribosomal subunit pre-mRNA 5'-splice site binding RNA binding structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Re... |
cytoplasmic translation maintenance of translational fidelity ribosomal large subunit assembly rRNA processing translation | cytoplasm; cytosol; cytosolic large ribosomal subunit | RNA binding structural constituent of ribosome | Saccharomyces cerevisiae | 3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Methylation Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation | MSHRKYEAPR | MSHRKYEAPRHGHLGFLPRKRAASIRARVKAFPKDDRSKPVALTSFLGYKAGMTTIVRDLDRPGSKFHKREVVEAVTVVDTPPVVVVGVVGYVETPRGLRSLTTVWAEHLSDEVKRRFYKNWYKSKKKAFTKYSAKYAQDGAGIERELARIKKYASVVRVLVHTQIRKTPLAQKKAHLAEIQLNGGSISEKVDWAREHFEKTVAVDSVFEQNEMIDAIAVTKGHGFEGVTHRWGTKKLPRKTHRGLRKVACIGAWHPAHVMWSVARAGQRGYHSRTSINHKIYRVGKGDDEANGATSFDRTKKTITPMGGFVHYGEIKND... | cytoplasmic translation maintenance of translational fidelity ribosomal large subunit assembly rRNA processing translation cytoplasm; cytosol; cytosolic large ribosomal subunit RNA binding structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Methy... |
cellular response to leukemia inhibitory factor cytoplasmic translation maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosomal small subunit biogenesis rRNA processing translation at postsynapse translation at presynapse | cytoplasm; cytosol; cytosolic ribosome; cytosolic small ribosomal subunit; nucleolus; postsynapse; presynapse; ribosome; small ribosomal subunit; small-subunit processome; synapse | RNA binding structural constituent of ribosome | Mus musculus | 3D-structure Acetylation Cytoplasm Nucleus Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein | MPSKGPLQSV | MPSKGPLQSVQVFGRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKLLEPVLLLGKERFAGVDIRVRVKGGGHVAQIYAIRQSISKALVAYYQKYVDEASKKEIKDILIQYDRTLLVADPRRCESKKFGGPGARARYQKSYR | cellular response to leukemia inhibitory factor cytoplasmic translation maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosomal small subunit biogenesis rRNA processing translation at postsynapse translation at presynapse cytoplasm; cytosol; cytosolic ribosome; cytosolic small... |
astrocyte development Bergmann glial cell differentiation D-aspartate import across plasma membrane extracellular matrix organization gene expression intermediate filament organization intracellular protein transport long-term synaptic potentiation negative regulation of neuron projection development neuron projection ... | astrocyte end-foot; cell body; cell projection; cytoplasm; cytoplasmic side of lysosomal membrane; cytosol; intermediate filament; intermediate filament cytoskeleton | identical protein binding integrin binding kinase binding structural constituent of cytoskeleton | Homo sapiens | 3D-structure Alternative splicing Citrullination Coiled coil Cytoplasm Direct protein sequencing Disease variant Intermediate filament Leukodystrophy Methylation Phosphoprotein Reference proteome | MERRRITSAA | MERRRITSAARRSYVSSGEMMVGGLAPGRRLGPGTRLSLARMPPPLPTRVDFSLAGALNAGFKETRASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAELRELRLRLDQLTANSARLEVERDNLAQDLATVRQKLQDETNLRLEAENNLAAYRQEADEATLARLDLERKIESLEEEIRFLRKIHEEEVRELQEQLARQQVHVELDVAKPDLTAALKEIRTQYEAMASSNMHEAEEWYRSKFADLTDAAARNAELLRQAKHEANDYRRQLQSLTCDLESLRGTNESLERQMREQEERHVRE... | astrocyte development Bergmann glial cell differentiation D-aspartate import across plasma membrane extracellular matrix organization gene expression intermediate filament organization intracellular protein transport long-term synaptic potentiation negative regulation of neuron projection development neuron projection ... |
axon extension axon guidance blood circulation cell population proliferation cell surface receptor signaling pathway cell-cell signaling establishment of localization in cell intracellular calcium ion homeostasis intracellular magnesium ion homeostasis melanocyte differentiation neural crest cell migration neutrophil c... | extracellular region; extracellular space | endothelin B receptor binding hormone activity signaling receptor binding | Homo sapiens | 3D-structure Alternative splicing Cleavage on pair of basic residues Deafness Direct protein sequencing Disease variant Disulfide bond Hirschsprung disease Reference proteome Secreted Signal Vasoactive Vasoconstrictor Waardenburg syndrome | MEPGLWLLFG | MEPGLWLLFGLTVTSAAGFVPCSQSGDAGRRGVSQAPTAARSEGDCEETVAGPGEETVAGPGEGTVAPTALQGPSPGSPGQEQAAEGAPEHHRSRRCTCFTYKDKECVYYCHLDIIWINTPEQTVPYGLSNYRGSFRGKRSAGPLPGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVSSNSRTAEKTDKEEEGKVEVKDQQSKQALDLHHPKLMPGSGLALAPSTCPRCLFQEGAP | axon extension axon guidance blood circulation cell population proliferation cell surface receptor signaling pathway cell-cell signaling establishment of localization in cell intracellular calcium ion homeostasis intracellular magnesium ion homeostasis melanocyte differentiation neural crest cell migration neutrophil c... |
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