Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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defense response to bacterium defense response to nematode eosinophil migration hydrogen peroxide catabolic process negative regulation of interleukin-10 production negative regulation of interleukin-5 production negative regulation of macrophage cytokine production positive regulation of interleukin-4 production respo... | extracellular exosome; extracellular region; extracellular space; secretory granule lumen | heme binding lactoperoxidase activity metal ion binding peroxidase activity | Homo sapiens | Calcium Direct protein sequencing Disease variant Disulfide bond Glycoprotein Heme Hydrogen peroxide Iron Metal-binding Nitration Oxidoreductase Peroxidase Reference proteome Signal | MHLLPALAGV | MHLLPALAGVLATLVLAQPCEGTDPASPGAVETSVLRDCIAEAKLLVDAAYNWTQKSIKQRLRSGSASPMDLLSYFKQPVAATRTVVRAADYMHVALGLLEEKLQPQRSGPFNVTDVLTEPQLRLLSQASGCALRDQAERCSDKYRTITGRCNNKRRPLLGASNQALARWLPAEYEDGLSLPFGWTPSRRRNGFLLPLVRAVSNQIVRFPNERLTSDRGRALMFMQWGQFIDHDLDFSPESPARVAFTAGVDCERTCAQLPPCFPIKIPPNDPRIKNQRDCIPFFRSAPSCPQNKNRVRNQINALTSFVDASMVYGSEVS... | defense response to bacterium defense response to nematode eosinophil migration hydrogen peroxide catabolic process negative regulation of interleukin-10 production negative regulation of interleukin-5 production negative regulation of macrophage cytokine production positive regulation of interleukin-4 production respo... |
cell differentiation involved in embryonic placenta development extrinsic apoptotic signaling pathway hepatocyte apoptotic process response to hydrostatic pressure response to other organism sarcomere organization tumor necrosis factor-mediated signaling pathway | apicolateral plasma membrane; cell periphery; cell-cell junction; costamere; cytoplasm; dystrophin-associated glycoprotein complex; intermediate filament; intermediate filament cytoskeleton; keratin filament; nuclear matrix; nucleoplasm; sarcolemma; Z disc | protein-containing complex binding scaffold protein binding | Mus musculus | Acetylation Coiled coil Cytoplasm Direct protein sequencing Glycoprotein Intermediate filament Isopeptide bond Keratin Methylation Nucleus Phosphoprotein Reference proteome Ubl conjugation | MSIRVTQKSY | MSIRVTQKSYKMSTSGPRAFSSRSFTSGPGARISSSSFSRVGSSSSSFRGSMGTGVGLGGFGGAGVGGITAVTVNQSLLSPLKLEVDPNIQAVRTQEKEQIKSLNNKFASFIDKVRFLEQQNKMLETKWSLLQQQKTSRSNMDNMFESYINNLRRQLEALGQEKLKLEAELGNMQGLVEDFKNKYEDEINKRTEMENEFVLIKKDVDEAYMNKVELESRLEGLTDEINFLRQIHEEEIRELQSQISDTSVVLSMDNSRSLDMDGIIAEVRAQYEDIANRSRAEAETMYQIKYEELQTLAGKHGDDLRRTKTEISEMNRNI... | cell differentiation involved in embryonic placenta development extrinsic apoptotic signaling pathway hepatocyte apoptotic process response to hydrostatic pressure response to other organism sarcomere organization tumor necrosis factor-mediated signaling pathway apicolateral plasma membrane; cell periphery; cell-cell j... |
embryo implantation female pregnancy negative regulation of interleukin-13 production negative regulation of interleukin-4 production negative regulation of interleukin-5 production negative regulation of T cell proliferation negative regulation of transcription by RNA polymerase II negative regulation of type II inter... | cytoplasm; extracellular exosome; extracellular space; nuclear envelope; secretory granule | phospholipase A2 inhibitor activity polychlorinated biphenyl binding | Homo sapiens | 3D-structure Direct protein sequencing Disulfide bond Phospholipase A2 inhibitor Reference proteome Secreted Signal | MKLAVTLTLV | MKLAVTLTLVTLALCCSSASAEICPSFQRVIETLLMDTPSSYEAAMELFSPDQDMREAGAQLKKLVDTLPQKPRESIIKLMEKIAQSSLCN | embryo implantation female pregnancy negative regulation of interleukin-13 production negative regulation of interleukin-4 production negative regulation of interleukin-5 production negative regulation of T cell proliferation negative regulation of transcription by RNA polymerase II negative regulation of type II inter... |
cellular response to mechanical stimulus cellular response to nitric oxide circadian rhythm respiratory gaseous exchange by respiratory system response to cAMP response to glucocorticoid response to glucose response to growth factor response to hormone response to hyperoxia response to interleukin-6 response to lipopol... | alveolar lamellar body; cytoplasm; extracellular region; extracellular space; multivesicular body | identical protein binding | Rattus norvegicus | Disulfide bond Gaseous exchange Lipoprotein Palmitate Reference proteome Secreted Surface film | MDMGSKEVLM | MDMGSKEVLMESPPDYSTGPRSQFRIPCCPVHLKRLLIVVVVVVLVVVVIVGALLMGLHMSQKHTEMVLEMSIGGAPETQKRLALSEHTDTIATFSIGSTGIVLYDYQRLLTAYKPAPGTYCYIMKMAPESIPSLEALARKFKNFQAKSSTPTSKLGQEEGHSAGSDSDSSGRDLAFLGLAVSTLCGELPLYYI | cellular response to mechanical stimulus cellular response to nitric oxide circadian rhythm respiratory gaseous exchange by respiratory system response to cAMP response to glucocorticoid response to glucose response to growth factor response to hormone response to hyperoxia response to interleukin-6 response to lipopol... |
respiratory gaseous exchange by respiratory system | alveolar lamellar body; clathrin-coated endocytic vesicle; endoplasmic reticulum membrane; extracellular region; extracellular space; lamellar body; multivesicular body lumen | identical protein binding | Homo sapiens | 3D-structure Alternative splicing Direct protein sequencing Disease variant Disulfide bond Gaseous exchange Lipoprotein Palmitate Reference proteome Secreted Surface film | MDVGSKEVLM | MDVGSKEVLMESPPDYSAAPRGRFGIPCCPVHLKRLLIVVVVVVLIVVVIVGALLMGLHMSQKHTEMVLEMSIGAPEAQQRLALSEHLVTTATFSIGSTGLVVYDYQQLLIAYKPAPGTCCYIMKIAPESIPSLEALTRKVHNFQMECSLQAKPAVPTSKLGQAEGRDAGSAPSGGDPAFLGMAVSTLCGEVPLYYI | respiratory gaseous exchange by respiratory system alveolar lamellar body; clathrin-coated endocytic vesicle; endoplasmic reticulum membrane; extracellular region; extracellular space; lamellar body; multivesicular body lumen identical protein binding Homo sapiens 3D-structure Alternative splicing Direct protein sequen... |
malate metabolic process NADH metabolic process oxaloacetate metabolic process tricarboxylic acid cycle | cytosol | hydroxyphenylpyruvate reductase activity L-malate dehydrogenase activity NAD binding | Sus scrofa | 3D-structure Acetylation Cytoplasm Direct protein sequencing Methylation NAD Oxidoreductase Phosphoprotein Reference proteome Tricarboxylic acid cycle Ubl conjugation | MSEPIRVLVT | MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDCALPLLKDVIATDKEEIAFKDLDVAILVGSMPRRDGMERKDLLKANVKIFKCQGAALDKYAKKSVKVIVVGNPANTNCLTASKSAPSIPKENFSCLTRLDHNRAKAQIALKLGVTSDDVKNVIIWGNHSSTQYPDVNHAKVKLQAKEVGVYEAVKDDSWLKGEFITTVQQRGAAVIKARKLSSAMSAAKAICDHVRDIWFGTPEGEFVSMGIISDGNSYGVPDDLLYSFPVTIKDKTWKIVEGLPINDFSREKMDLTAKEL... | malate metabolic process NADH metabolic process oxaloacetate metabolic process tricarboxylic acid cycle cytosol hydroxyphenylpyruvate reductase activity L-malate dehydrogenase activity NAD binding Sus scrofa 3D-structure Acetylation Cytoplasm Direct protein sequencing Methylation NAD Oxidoreductase Phosphoprotein Refer... |
2-micrometer plasmid partitioning cell division establishment of mitotic spindle orientation karyogamy involved in conjugation with cellular fusion mitotic spindle elongation negative regulation of microtubule polymerization nuclear migration involved in conjugation with cellular fusion | cell cortex; cell tip; kinetochore; mating projection tip; microtubule associated complex; microtubule plus-end; spindle; spindle microtubule; spindle pole body | microtubule binding | Saccharomyces cerevisiae | 3D-structure Cell cycle Cell division Coiled coil Cytoplasm Cytoskeleton Microtubule Mitosis Phosphoprotein Reference proteome | MDRYQRKIGC | MDRYQRKIGCFIQIPNLGRGQLKYVGPVDTKAGMFAGVDLLANIGKNDGSFMGKKYFQTEYPQSGLFIQLQKVASLIEKASISQTSRRTTMEPLSIPKNRSIVRLTNQFSPMDDPKSPTPMRSFRITSRHSGNQQSMDQEASDHHQQQEFGYDNREDRMEVDSILSSDRKANHNTTSDWKPDNGHMNDLNSSEVTIELREAQLTIEKLQRKQLHYKRLLDDQRMVLEEVQPTFDRYEATIQEREKEIDHLKQQLELERRQQAKQKQFFDAENEQLLAVVSQLHEEIKENEERNLSHNQPTGANEDVELLKKQLEQLRNIE... | 2-micrometer plasmid partitioning cell division establishment of mitotic spindle orientation karyogamy involved in conjugation with cellular fusion mitotic spindle elongation negative regulation of microtubule polymerization nuclear migration involved in conjugation with cellular fusion cell cortex; cell tip; kinetocho... |
coumarin metabolic process epoxygenase P450 pathway xenobiotic metabolic process | cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle | arachidonic acid epoxygenase activity aromatase activity heme binding iron ion binding oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen steroid hydroxylase a... | Rattus norvegicus | Direct protein sequencing Endoplasmic reticulum Heme Iron Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Phosphoprotein Reference proteome | MLDTGLLLVV | MLDTGLLLVVILASLSVMLLVSLWQQKIRGRLPPGPTPLPFIGNYLQLNTKDVYSSITQLSERYGPVFTIHLGPRRVVVLYGYDAVKEALVDQAEEFSGRGEQATYNTLFKGYGVAFSSGERAKQLRRLSIATLRDFGVGKRGVEERILEEAGYLIKMLQGTCGAPIDPTIYLSKTVSNVISSIVFGERFDYEDTEFLSLLQMMGQMNRFAASPTGQLYDMFHSVMKYLPGPQQQIIKVTQKLEDFMIEKVRQNHSTLDPNSPRNFIDSFLIRMQEEKNGNSEFHMKNLVMTTLSLFFAGSETVSSTLRYGFLLLMKHPD... | coumarin metabolic process epoxygenase P450 pathway xenobiotic metabolic process cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle arachidonic acid epoxygenase activity aromatase activity heme binding iron ion binding oxidoreductase activity oxidoreductase activity, acting on paired do... |
amide metabolic process cholesterol metabolic process epoxygenase P450 pathway estrogen metabolic process icosanoid biosynthetic process long-chain fatty acid biosynthetic process monocarboxylic acid metabolic process monoterpenoid metabolic process omega-hydroxylase P450 pathway oxidative demethylation steroid metabol... | cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; plasma membrane | (R)-limonene 6-monooxygenase activity (S)-limonene 6-monooxygenase activity (S)-limonene 7-monooxygenase activity arachidonic acid 11,12-epoxygenase activity arachidonic acid 14,15-epoxygenase activity arachidonic acid epoxygenase activity aromatase activity caffeine oxidase activity heme binding iron ion binding monoo... | Homo sapiens | 3D-structure Alternative splicing Direct protein sequencing Endoplasmic reticulum Heme Iron Lipid metabolism Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Reference proteome Steroid metabolism Sterol metabolism | MDSLVVLVLC | MDSLVVLVLCLSCLLLLSLWRQSSGRGKLPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLNENIKILSSPWIQICNNFSPIIDYFPGTHNKLLKNVAFMKSYILEKVKEHQESMDMNNPQDFIDCFLMKMEKEKHNQPSEFTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVT... | amide metabolic process cholesterol metabolic process epoxygenase P450 pathway estrogen metabolic process icosanoid biosynthetic process long-chain fatty acid biosynthetic process monocarboxylic acid metabolic process monoterpenoid metabolic process omega-hydroxylase P450 pathway oxidative demethylation steroid metabol... |
arachidonic acid metabolic process xenobiotic metabolic process | cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; mitochondrion | anandamide 11,12 epoxidase activity anandamide 14,15 epoxidase activity anandamide 8,9 epoxidase activity aromatase activity heme binding iron ion binding monooxygenase activity oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin ... | Mus musculus | Endoplasmic reticulum Heme Iron Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Phosphoprotein Reference proteome | MELLTGTDLW | MELLTGTDLWPVAIFTVIFILLVDLTHQRQRWTSRYPPGPVPWPVLGNLLQVDLGNMPYSLYKLQNRYGDVFSLQMAWKPMVVINGLKAMKEMLLTCGEDTADRPPVPIFEYLGVKPGSQGVVLAPYGPEWREQRRFSVSTLRNFGLGKKSLEDWVTKEANHLCDAFTAQAGQPINPNPMLNKSTCNVIASLIFARRFEYEDPFLIRMLKVLEQSLTEVSGLIPEVLNAFPILLRIPRLADKALQGQKSFIAILDNLLTENRTTWDPVQAPRNLTDAFLAEIEKAKGNPESSFNDENLLMVVRDLFGAGMLTTSTTLSWA... | arachidonic acid metabolic process xenobiotic metabolic process cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; mitochondrion anandamide 11,12 epoxidase activity anandamide 14,15 epoxidase activity anandamide 8,9 epoxidase activity aromatase activity heme binding iron ion binding mo... |
DNA-templated transcription positive regulation of amino acid biosynthetic process regulation of DNA-templated transcription tryptophan biosynthetic process | protein-DNA complex | DNA-binding transcription factor activity sequence-specific DNA binding | Pseudomonas aeruginosa | Activator Amino-acid biosynthesis Aromatic amino acid biosynthesis DNA-binding Reference proteome Repressor Transcription Transcription regulation Tryptophan biosynthesis | MSRDLPSLNA | MSRDLPSLNALRAFEAAARLHSISLAAEELHVTHGAVSRQVRLLEDDLGVALFGKDGRGVKLTDSGVRLRDACGDAFERLRGVCAELRRQTAEAPFVLGVPGSLLARWFIPRLDQLNRALPDLRLQLSTSEGEFDPRRPGLDAMLWFAEPPWPADMQVFELAPERMGPVVSPRLAQETGLAQAPAARLLQEPLLHTASRPQAWPAWAASQGLAAEALRYGQGFEHLYYLLEAAVAGLGVAIAPEPLVRDDLAAGRLAAPWGFIETDARLALWVPARLHDPRAGRLAQWLREQLAG | DNA-templated transcription positive regulation of amino acid biosynthetic process regulation of DNA-templated transcription tryptophan biosynthetic process protein-DNA complex DNA-binding transcription factor activity sequence-specific DNA binding Pseudomonas aeruginosa Activator Amino-acid biosynthesis Aromatic amino... |
ammonium homeostasis arginine biosynthetic process via ornithine citrulline biosynthetic process liver development midgut development monoatomic anion homeostasis ornithine catabolic process ornithine metabolic process response to biotin response to insulin response to xenobiotic stimulus response to zinc ion urea cycl... | mitochondrial inner membrane; mitochondrial matrix; mitochondrion | amino acid binding identical protein binding ornithine carbamoyltransferase activity phosphate ion binding phospholipid binding | Mus musculus | Acetylation Amino-acid biosynthesis Arginine biosynthesis Disease variant Mitochondrion Phosphoprotein Reference proteome Transferase Transit peptide Urea cycle | MLSNLRILLN | MLSNLRILLNNAALRKGHTSVVRHFWCGKPVQSQVQLKGRDLLTLKNFTGEEIQYMLWLSADLKFRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPSFLTTQDIHLGVNESLTDTARVLSSMTDAVLARVYKQSDLDTLAKEASIPIVNGLSDLYHPIQILADYLTLQEHYGSLKGLTLSWIGDGNNILHSIMMSAAKFGMHLQAATPKGYEPDPNIVKLAEQYAKENGTKLSMTNDPLEAARGGNVLITDTWISMGQEDEKKKRLQAFQGYQVTMKTAKVAASDWTFLHCLPRKPEEVDDEVFYSPR... | ammonium homeostasis arginine biosynthetic process via ornithine citrulline biosynthetic process liver development midgut development monoatomic anion homeostasis ornithine catabolic process ornithine metabolic process response to biotin response to insulin response to xenobiotic stimulus response to zinc ion urea cycl... |
calcium ion transport cell differentiation G1/S transition of mitotic cell cycle nervous system development phosphorylation regulation of long-term neuronal synaptic plasticity regulation of neuron projection development regulation of protein localization to plasma membrane regulation of relaxation of cardiac muscle re... | calcium- and calmodulin-dependent protein kinase complex; cytoplasm; cytosol; neuron projection; nucleoplasm; postsynaptic density; sarcoplasmic reticulum membrane | ATP binding calmodulin binding calmodulin-dependent protein kinase activity identical protein binding protein homodimerization activity protein serine kinase activity protein serine/threonine kinase activity | Rattus norvegicus | Alternative splicing ATP-binding Calmodulin-binding Developmental protein Differentiation Kinase Membrane Neurogenesis Nucleotide-binding Phosphoprotein Reference proteome Sarcoplasmic reticulum Serine/threonine-protein kinase Transferase | MATTATCTRF | MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSVGRQS... | calcium ion transport cell differentiation G1/S transition of mitotic cell cycle nervous system development phosphorylation regulation of long-term neuronal synaptic plasticity regulation of neuron projection development regulation of protein localization to plasma membrane regulation of relaxation of cardiac muscle re... |
nucleocytoplasmic transport protein import into nucleus ribosomal subunit export from nucleus RNA import into nucleus rRNA export from nucleus subtelomeric heterochromatin formation tRNA export from nucleus | chromosome, telomeric region; cytosol; nucleus; perinuclear region of cytoplasm | GTPase activator activity small GTPase binding | Saccharomyces cerevisiae | Cytoplasm GTPase activation Leucine-rich repeat Phosphoprotein Reference proteome Repeat | MATLHFVPQH | MATLHFVPQHEEEQVYSISGKALKLTTSDDIKPYLEELAALKTCTKLDLSGNTIGTEASEALAKCIAENTQVRESLVEVNFADLYTSRLVDEVVDSLKFLLPVLLKCPHLEIVNLSDNAFGLRTIELLEDYIAHAVNIKHLILSNNGMGPFAGERIGKALFHLAQNKKAASKPFLETFICGRNRLENGSAVYLALGLKSHSEGLKVVKLYQNGIRPKGVATLIHYGLQYLKNLEILDLQDNTFTKHASLILAKALPTWKDSLFELNLNDCLLKTAGSDEVFKVFTEVKFPNLHVLKFEYNEMAQETIEVSFLPAMEKGNL... | nucleocytoplasmic transport protein import into nucleus ribosomal subunit export from nucleus RNA import into nucleus rRNA export from nucleus subtelomeric heterochromatin formation tRNA export from nucleus chromosome, telomeric region; cytosol; nucleus; perinuclear region of cytoplasm GTPase activator activity small G... |
arginine metabolic process cell cycle negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of arginine metabolic process regulation of mating type switching regulation of mating-type specific transcription, DNA-templated | chromatin; cytosol; nucleus; RNA polymerase II transcription regulator complex; RNA polymerase II transcription repressor complex | DNA replication origin binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific molecular sequestering activity protein dimerization activity RNA polymer... | Saccharomyces cerevisiae | 3D-structure Acetylation Activator Arginine metabolism Cell cycle DNA-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MSDIEEGTPT | MSDIEEGTPTNNGQQKERRKIEIKFIENKTRRHVTFSKRKHGIMKKAFELSVLTGTQVLLLVVSETGLVYTFSTPKFEPIVTQQEGRNLIQACLNAPDDEEEDEEEDGDDDDDDDDDGNDMQRQQPQQQQPQQQQQVLNAHANSLGHLNQDQVPAGALKQEVKSQLLGGANPNQNSMIQQQQHHTQNSQPQQQQQQQPQQQMSQQQMSQHPRPQQGIPHPQQSQPQQQQQQQQQLQQQQQQQQQQPLTGIHQPHQQAFANAASPYLNAEQNAAYQQYFQEPQQGQY | arginine metabolic process cell cycle negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of arginine metabolic process regulation of mating type switching regulation of mating-type specific transcription, DNA-templated chromatin; cytosol; nucle... |
positive regulation of transcription by RNA polymerase II RNA polymerase II preinitiation complex assembly transcription by RNA polymerase II | nucleus; transcription factor TFIID complex | protein heterodimerization activity | Saccharomyces cerevisiae | Coiled coil Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MSRKLKKTNL | MSRKLKKTNLFNKDVSSLLYAYGDVPQPLQATVQCLDELVSGYLVDVCTNAFHTAQNSQRNKLRLEDFKFALRKDPIKLGRAEELIATNKLITEAKKQFNETDNQNSLKRYREEDEEGDEMEEDEDEQQVTDDDEEAAGRNSAKQSTDSKATKIRKQGPKNLKKTKK | positive regulation of transcription by RNA polymerase II RNA polymerase II preinitiation complex assembly transcription by RNA polymerase II nucleus; transcription factor TFIID complex protein heterodimerization activity Saccharomyces cerevisiae Coiled coil Nucleus Phosphoprotein Reference proteome Transcription Tran... |
apoptotic process cell-cell adhesion cellular response to glucose stimulus cellular response to organic cyclic compound myoblast differentiation negative regulation of cell-substrate adhesion negative regulation of neuron projection development plasma cell differentiation positive regulation of apoptotic process positi... | cell surface; cytoplasm; extracellular space; galectin complex | carbohydrate binding identical protein binding lactose binding laminin binding | Rattus norvegicus | 3D-structure Acetylation Apoptosis Cytoplasm Direct protein sequencing Extracellular matrix Lectin Phosphoprotein Reference proteome Secreted | MACGLVASNL | MACGLVASNLNLKPGECLKVRGELAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNSKDDGTWGTEQRETAFPFQPGSITEVCITFDQADLTIKLPDGHEFKFPNRLNMEAINYMAADGDFKIKCVAFE | apoptotic process cell-cell adhesion cellular response to glucose stimulus cellular response to organic cyclic compound myoblast differentiation negative regulation of cell-substrate adhesion negative regulation of neuron projection development plasma cell differentiation positive regulation of apoptotic process positi... |
ethanol oxidation fatty acid omega-oxidation formaldehyde catabolic process positive regulation of blood pressure respiratory system process response to lipopolysaccharide response to nitrosative stress response to redox state retinoid metabolic process | cytosol; extracellular exosome; mitochondrion | alcohol dehydrogenase activity, zinc-dependent electron transfer activity fatty acid binding formaldehyde dehydrogenase activity identical protein binding S-(hydroxymethyl)glutathione dehydrogenase activity S-(hydroxymethyl)glutathione dehydrogenase NAD activity S-(hydroxymethyl)glutathione dehydrogenase NADP activity ... | Homo sapiens | 3D-structure Acetylation Cytoplasm Direct protein sequencing Disease variant Dwarfism Intellectual disability Lipid metabolism Metal-binding NAD Oxidoreductase Phosphoprotein Reference proteome Zinc | MANEVIKCKA | MANEVIKCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKIIATAVCHTDAYTLSGADPEGCFPVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGKGLMPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTGYGAAVNTAKLEPGSVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATECINPQDFSKPIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAASGEEIATRPFQLVTGRTWKGTAFG... | ethanol oxidation fatty acid omega-oxidation formaldehyde catabolic process positive regulation of blood pressure respiratory system process response to lipopolysaccharide response to nitrosative stress response to redox state retinoid metabolic process cytosol; extracellular exosome; mitochondrion alcohol dehydrogenas... |
intracellular signal transduction phosphorylation positive regulation of hydrogen sulfide biosynthetic process positive regulation of ribosomal protein gene transcription by RNA polymerase II positive regulation of transcription by RNA polymerase I positive regulation of transcription by RNA polymerase III regulation o... | chromatin; cytoplasm; fungal-type vacuole membrane; nucleus | ATP binding protein serine kinase activity protein serine/threonine kinase activity | Saccharomyces cerevisiae | ATP-binding cAMP Kinase Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MMNFFTSKSS | MMNFFTSKSSNQDTGFSSQHQHPNGQNNGNNNSSTAGNDNGYPCKLVSSGPCASSNNGALFTNFTLQTATPTTAISQDLYAMGTTGITSENALFQMKSMNNGISSVNNNNSNTPTIITTSQEETNAGNVHGDTGGNSLQNSEDDNFSSSSTTKCLLSSTSSLSINQREAAAAAYGPDTDIPRGKLEVTIIEARDLVTRSKDSQPYVVCTFESSEFISNGPESLGAINNNNNNNNNNQHNQNQHINNNNENTNPDAASQHHNNNSGWNGSQLPSIKEHLKKKPLYTHRSSSQLDQLNSCSSVTDPSKRSSNSSSGSSNGPK... | intracellular signal transduction phosphorylation positive regulation of hydrogen sulfide biosynthetic process positive regulation of ribosomal protein gene transcription by RNA polymerase II positive regulation of transcription by RNA polymerase I positive regulation of transcription by RNA polymerase III regulation o... |
determination of left/right symmetry heart development phosphorylation | centrosome; cytosol; endoplasmic reticulum membrane; Golgi apparatus; nuclear speck; plasma membrane | ATP binding protein serine kinase activity protein serine/threonine kinase activity | Homo sapiens | ATP-binding Cell membrane Cytoplasm Cytoskeleton Endoplasmic reticulum Golgi apparatus Kinase Lipoprotein Membrane Myristate Nucleotide-binding Nucleus Palmitate Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MGCGTSKVLP | MGCGTSKVLPEPPKDVQLDLVKKVEPFSGTKSDVYKHFITEVDSVGPVKAGFPAASQYAHPCPGPPTAGHTEPPSEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEP... | determination of left/right symmetry heart development phosphorylation centrosome; cytosol; endoplasmic reticulum membrane; Golgi apparatus; nuclear speck; plasma membrane ATP binding protein serine kinase activity protein serine/threonine kinase activity Homo sapiens ATP-binding Cell membrane Cytoplasm Cytoskeleton En... |
cell division cellular response to interleukin-4 cellular response to ionomycin cellular response to lipopolysaccharide cellular response to phorbol 13-acetate 12-myristate G1/S transition of mitotic cell cycle positive regulation of cell population proliferation positive regulation of fibroblast proliferation positive... | bicellular tight junction; chromatin; cyclin D1-CDK4 complex; cyclin D2-CDK4 complex; cyclin D3-CDK4 complex; cyclin-dependent protein kinase holoenzyme complex; cytoplasm; cytosol; nuclear membrane; nucleolus; nucleoplasm; nucleus; transcription regulator complex | ATP binding cyclin binding cyclin-dependent protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase regulator activity protein serine kinase activity | Homo sapiens | 3D-structure Acetylation Alternative splicing ATP-binding Cell cycle Cell division Cytoplasm Disease variant Kinase Membrane Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MATSRYEPVA | MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPRDVSLPRGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKDEGNPE | cell division cellular response to interleukin-4 cellular response to ionomycin cellular response to lipopolysaccharide cellular response to phorbol 13-acetate 12-myristate G1/S transition of mitotic cell cycle positive regulation of cell population proliferation positive regulation of fibroblast proliferation positive... |
nitrate assimilation nitric oxide biosynthetic process response to herbicide response to light stimulus | cytosol | FAD binding heme binding molybdenum ion binding molybdopterin cofactor binding nitrate reductase (NADH) activity nitrate reductase (NADPH) activity nitrate reductase activity | Arabidopsis thaliana | Disulfide bond FAD Flavoprotein Heme Herbicide resistance Iron Metal-binding Molybdenum NAD Nitrate assimilation Oxidoreductase Reference proteome | MATSVDNRHY | MATSVDNRHYPTMNGVAHAFKPPLVPSPRSFDRHRHQNQTLDVILTETKIVKETEVITTVVDSYDDSSSDDEDESHNRNVPYYKELVKKSNSDLEPSILDPRDESTADSWIQRNSSMLRLTGKHPFNAEAPLPRLMHHGFITPVPLHYVRNHGAVPKANWSDWSIEITGLVKRPAKFTMEELISEFPSREFPVTLVCAGNRRKEQNMVKQTIGFNWGSAGVSTSLWKGIPLSEILRRCGIYSRRGGALNVCFEGAEDLPGGGGSKYGTSIKKEMAMDPARDIILAYMQNGELLTPDHGFPVRVIVPGFIGGRMVKWLKRI... | nitrate assimilation nitric oxide biosynthetic process response to herbicide response to light stimulus cytosol FAD binding heme binding molybdenum ion binding molybdopterin cofactor binding nitrate reductase (NADH) activity nitrate reductase (NADPH) activity nitrate reductase activity Arabidopsis thaliana Disulfide bo... |
activated T cell proliferation amyloid-beta clearance cell adhesion cell-cell adhesion cell-matrix adhesion cellular extravasation cellular response to low-density lipoprotein particle stimulus endothelial cell migration heterotypic cell-cell adhesion integrin-mediated signaling pathway leukocyte cell-cell adhesion leu... | cell surface; external side of plasma membrane; focal adhesion; integrin alphaL-beta2 complex; integrin alphaM-beta2 complex; integrin complex; membrane; membrane raft; plasma membrane; plasma membrane raft; receptor complex | amyloid-beta binding cell adhesion molecule binding complement component C3b binding heat shock protein binding ICAM-3 receptor activity integrin binding metal ion binding protein kinase binding protein-containing complex binding | Mus musculus | Calcium Cell adhesion Cell membrane Disulfide bond EGF-like domain Glycoprotein Integrin Magnesium Membrane Metal-binding Phagocytosis Phosphoprotein Pyrrolidone carboxylic acid Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix | MLGLRPSLLL | MLGLRPSLLLALAGLFFLGSAVSQECTKYKVSSCRDCIQSGPGCSWCQKLNFTGPGEPDSLRCDTRAQLLLKGCPADDIMDPRSIANPEFDQRGQRKQLSPQKVTLYLRPGQAAAFNVTFRRAKGYPIDLYYLMDLSYSMLDDLNNVKKLGGDLLQALNEITESGRIGFGSFVDKTVLPFVNTHPEKLRNPCPNKEKACQPPFAFRHVLKLTDNSNQFQTEVGKQLISGNLDAPEGGLDAIMQVAACPEEIGWRNVTRLLVFATDDGFHFAGDGKLGAILTPNDGRCHLEDNMYKRSNEFDYPSVGQLAHKLSESNIQPI... | activated T cell proliferation amyloid-beta clearance cell adhesion cell-cell adhesion cell-matrix adhesion cellular extravasation cellular response to low-density lipoprotein particle stimulus endothelial cell migration heterotypic cell-cell adhesion integrin-mediated signaling pathway leukocyte cell-cell adhesion leu... |
B cell activation B cell differentiation B cell proliferation B cell receptor signaling pathway calcium ion import into cytosol cell surface receptor signaling pathway humoral immune response positive regulation of calcium ion import across plasma membrane protein tetramerization response to bacterium store-operated ca... | cell surface; external side of plasma membrane; extracellular exosome; extracellular space; nucleoplasm; plasma membrane; plasma membrane raft | epidermal growth factor receptor binding identical protein binding immunoglobulin binding MHC class II protein complex binding | Homo sapiens | 3D-structure Alternative splicing B-cell activation Cell membrane Disulfide bond Lipoprotein Membrane Palmitate Pharmaceutical Phosphoprotein Reference proteome Transmembrane Transmembrane helix | MTTPRNSVNG | MTTPRNSVNGTFPAEPMKGPIAMQSGPKPLFRRMSSLVGPTQSFFMRESKTLGAVQIMNGLFHIALGGLLMIPAGIYAPICVTVWYPLWGGIMYIISGSLLAATEKNSRKCLVKGKMIMNSLSLFAAISGMILSIMDILNIKISHFLKMESLNFIRAHTPYINIYNCEPANPSEKNSPSTQYCYSIQSLFLGILSVMLIFAFFQELVIAGIVENEWKRTCSRPKSNIVLLSAEEKKEQTIEIKEEVVGLTETSSQPKNEEDIEIIPIQEEEEEETETNFPEPPQDQESSPIENDSSP | B cell activation B cell differentiation B cell proliferation B cell receptor signaling pathway calcium ion import into cytosol cell surface receptor signaling pathway humoral immune response positive regulation of calcium ion import across plasma membrane protein tetramerization response to bacterium store-operated ca... |
cell division chromosome segregation G2/M transition of mitotic cell cycle positive regulation of mitotic nuclear division protein phosphorylation | cytoplasm; mitotic spindle pole body; nucleus | ATP binding histone H3S10 kinase activity protein kinase activity protein serine kinase activity protein serine/threonine kinase activity | Emericella nidulans | ATP-binding Cell cycle Cell division Kinase Mitosis Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MAIALAEADK | MAIALAEADKYEVLEKIGCGSFGIIRKVKRKSDGFILCRKEINYIKMSTKEREQLTAEFNILSSLRHPNIVAYYHREHLKASQDLYLYMEYCGGGDLSMVIKNLKRTNKYAEEDFVWRILSQLVTALYRCHYGTDPAEVGSNLLGPAPKPSGLKGKQAQMTILHRDLKPENIFLGSDNTVKLGDFGLSKLMHSHDFASTYVGTPFYMSPEICAAEKYTLRSDIWAVGCIMYELCQREPPFNARTHIQLVQKIREGKFAPLPDFYSSELKNVIASCLRVNPDHRPDTATLINTPVIRLMRREVELNNLSRAARKREEATMQ... | cell division chromosome segregation G2/M transition of mitotic cell cycle positive regulation of mitotic nuclear division protein phosphorylation cytoplasm; mitotic spindle pole body; nucleus ATP binding histone H3S10 kinase activity protein kinase activity protein serine kinase activity protein serine/threonine kinas... |
glycogen metabolic process negative regulation of phosphoprotein phosphatase activity regulation of signal transduction | protein phosphatase type 1 complex; skeletal muscle myofibril | protein phosphatase 1 binding protein phosphatase inhibitor activity | Oryctolagus cuniculus | Acetylation Carbohydrate metabolism Direct protein sequencing Glycogen metabolism Phosphoprotein Protein phosphatase inhibitor Reference proteome | MAASTASHRP | MAASTASHRPIKGILKNKTSSTSSRVASAEQPRGSVDEELSKKSQKWDEMNILATYHPADKDYGLMKIDEPSTPYHSMIGDDDDAYSDTETTEAMTPDTLAKKLAAAEGSEPKYRIREQESSGEEDSDLSPEEREKKRQFEMKRKLHYNEGLNIKLARQLISKDLHDDEEDEEMSETADGESMNTEESNQGSTPSDQRQNKSQSS | glycogen metabolic process negative regulation of phosphoprotein phosphatase activity regulation of signal transduction protein phosphatase type 1 complex; skeletal muscle myofibril protein phosphatase 1 binding protein phosphatase inhibitor activity Oryctolagus cuniculus Acetylation Carbohydrate metabolism Direct prot... |
actin crosslink formation antral ovarian follicle growth apoptotic process basement membrane organization cell cycle initiation of primordial ovarian follicle growth ovulation regulation of cell cycle regulation of cell shape regulation of Notch signaling pathway | actin filament; cytoplasm; membrane; stress fiber | actin filament binding cytoskeletal anchor activity microtubule binding | Mus musculus | 3D-structure Apoptosis Cell cycle Cell shape Cytoplasm Cytoskeleton Growth arrest Membrane Phosphoprotein Reference proteome | MMCTALSPKV | MMCTALSPKVRSGPGLSDMHQYSQWLASRHEANLLPMKEDLALWLTNLLGKEITAETFMEKLDNGALLCQLAATVQEKFKESMDANKPAKTLPLKKIPCKASAPSGSFFARDNTANFLSWCRDLGVDETCLFESEGLVLHKQPREVCLCLLELGRIAARYGVEPPGLIKLEKEIEQEETLSAPSPSPSPSSKSSGKKSTGNLLDDAVKRISEDPPCKCPTKFCVERLSQGRYRVGEKILFIRMLHNKHVMVRVGGGWETFAGYLLKHDPCRMLQISRVDGKTSPVQSKSPTLKDMNPDNYLVVSATYKAKKEIK | actin crosslink formation antral ovarian follicle growth apoptotic process basement membrane organization cell cycle initiation of primordial ovarian follicle growth ovulation regulation of cell cycle regulation of cell shape regulation of Notch signaling pathway actin filament; cytoplasm; membrane; stress fiber actin ... |
acetate metabolic process anaerobic amino acid catabolic process L-threonine catabolic process to propionate phosphorylation threonine catabolic process | cytosol | acetate kinase activity ATP binding metal ion binding propionate kinase activity | Escherichia coli | ATP-binding Kinase Magnesium Metal-binding Nucleotide-binding Reference proteome Transferase | MNEFPVVLVI | MNEFPVVLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAFLSVNGGEPAPLAHHSYEGALKAIAFELEKRNLNDSVALIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAPLHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLPWKYYEELGVRRYGFHGTSHRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSGDVDFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERAQLAIKTFVHRIARHIAGHAASLRRLDG... | acetate metabolic process anaerobic amino acid catabolic process L-threonine catabolic process to propionate phosphorylation threonine catabolic process cytosol acetate kinase activity ATP binding metal ion binding propionate kinase activity Escherichia coli ATP-binding Kinase Magnesium Metal-binding Nucleotide-binding... |
cell cycle cell division cell wall organization peptidoglycan biosynthetic process regulation of cell shape | cytosol | ATP binding UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity | Escherichia coli | 3D-structure ATP-binding Cell cycle Cell division Cell shape Cell wall biogenesis/degradation Cytoplasm Direct protein sequencing Ligase Nucleotide-binding Peptidoglycan synthesis Reference proteome | MISVTLSQLT | MISVTLSQLTDILNGELQGADITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAGGAGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAAILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFSPNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVGATLDAIKAGLANLKAVPGRLFPI... | cell cycle cell division cell wall organization peptidoglycan biosynthetic process regulation of cell shape cytosol ATP binding UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity Escherichia coli 3D-structure AT... |
cellular aldehyde metabolic process lipid metabolic process positive regulation of cell population proliferation response to cAMP response to glucocorticoid response to hypoxia response to nutrient response to organic cyclic compound response to xenobiotic stimulus | cytoplasm; cytosol; membrane | 3-chloroallyl aldehyde dehydrogenase activity alcohol dehydrogenase (NADP+) activity aldehyde dehydrogenase (NAD+) activity benzaldehyde dehydrogenase (NAD+) activity oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | Rattus norvegicus | 3D-structure Acetylation Cytoplasm Direct protein sequencing Lipid metabolism NAD NADP Oxidoreductase Reference proteome | MSSISDTVKR | MSSISDTVKRAREAFNSGKTRSLQFRIQQLEALQRMINENLKSISGALASDLGKNEWTSYYEEVAHVLEELDTTIKELPDWAEDEPVAKTRQTQQDDLYIHSEPLGVVLVIGAWNYPFNLTIQPMVGAVAAGNAVILKPSEVSGHMADLLATLIPQYMDQNLYLVVKGGVPETTELLKERFDHIMYTGSTAVGKIVMAAAAKHLTPVTLELGGKSPCYVDKDCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKDFYGEDAKQSRDYGRIINDRHFQRVKGLIDNQKVAHGGTWDQSSRYIAPTI... | cellular aldehyde metabolic process lipid metabolic process positive regulation of cell population proliferation response to cAMP response to glucocorticoid response to hypoxia response to nutrient response to organic cyclic compound response to xenobiotic stimulus cytoplasm; cytosol; membrane 3-chloroallyl aldehyde de... |
acetaldehyde metabolic process aldehyde catabolic process apoptotic mitochondrial changes behavioral response to ethanol cellular detoxification of aldehyde cellular response to fatty acid cellular response to hormone stimulus cellular response to resveratrol ethanol catabolic process ethanol metabolic process intrinsi... | mitochondrial matrix | aldehyde dehydrogenase (NAD+) activity carboxylesterase activity glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity identical protein binding NADH binding nitroglycerin reductase activity phenylacetaldehyde dehydrogenase activity | Rattus norvegicus | 3D-structure Acetylation Direct protein sequencing Mitochondrion NAD Oxidoreductase Reference proteome Transit peptide | MLRAALSTAR | MLRAALSTARRGPRLSRLLSAAATSAVPAPNQQPEVFCNQIFINNEWHDAVSKKTFPTVNPSTGEVICQVAEGNKEDVDKAVKAAQAAFQLGSPWRRMDASDRGRLLYRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEVGHLIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQC... | acetaldehyde metabolic process aldehyde catabolic process apoptotic mitochondrial changes behavioral response to ethanol cellular detoxification of aldehyde cellular response to fatty acid cellular response to hormone stimulus cellular response to resveratrol ethanol catabolic process ethanol metabolic process intrinsi... |
neuropeptide signaling pathway | extracellular region | hormone activity | Aquarana catesbeiana | Amidation Cleavage on pair of basic residues Direct protein sequencing Endorphin Glycoprotein Hormone Pyrrolidone carboxylic acid Secreted Signal | MLQPVWHACI | MLQPVWHACILAILGVFIFHVGEVRSQCWESNKCTDLSSEDGILECIKACKMDLSAESPVFPGNGHIQPLSENIRKYVMSHFRWNKFGRRNSTSNDNNNNNGGYKREDIANYPILNLFLGSDNQNTQEGIMEDDALDRQDSKRSYSMEHFRWGKPVGKKRRPIKVFPTDAEEESSESFPIELRRELSLEFDYPDTNSEEELDNGELLEGPVKKGRKYKMHHFRWEGPPKDKRYGGFMTPERSQTPLMTLFKNAIIKNAHKKGQ | neuropeptide signaling pathway extracellular region hormone activity Aquarana catesbeiana Amidation Cleavage on pair of basic residues Direct protein sequencing Endorphin Glycoprotein Hormone Pyrrolidone carboxylic acid Secreted Signal MLQPVWHACI MLQPVWHACILAILGVFIFHVGEVRSQCWESNKCTDLSSEDGILECIKACKMDLSAESPVFPGNGHIQPLSE... |
5-phosphoribose 1-diphosphate biosynthetic process nucleobase-containing compound metabolic process pentose-phosphate shunt phosphorylation purine nucleotide biosynthetic process ribonucleoside monophosphate biosynthetic process | cytoplasm; cytosol; ribose phosphate diphosphokinase complex | ATP binding identical protein binding kinase activity magnesium ion binding protein homodimerization activity ribose phosphate diphosphokinase activity | Homo sapiens | 3D-structure Alternative splicing ATP-binding Direct protein sequencing Kinase Magnesium Metal-binding Nucleotide biosynthesis Nucleotide-binding Reference proteome Transferase | MPNIVLFSGS | MPNIVLFSGSSHQDLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGCGEINDNLMELLIMINACKIASSSRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENIAEWKNCIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATKVYAILTHGIFSGPAISRINNAAFEAVVVTNTIPQEDKMKHCTKIQVIDISMILAEAIRRTHNGESVSYLFSHVPL | 5-phosphoribose 1-diphosphate biosynthetic process nucleobase-containing compound metabolic process pentose-phosphate shunt phosphorylation purine nucleotide biosynthetic process ribonucleoside monophosphate biosynthetic process cytoplasm; cytosol; ribose phosphate diphosphokinase complex ATP binding identical protein ... |
arachidonic acid metabolic process lipoxygenase pathway response to oxidative stress | cytosol; mitochondrion | glutathione peroxidase activity phospholipid-hydroperoxide glutathione peroxidase activity | Oryctolagus cuniculus | Acetylation Cytoplasm Lipid metabolism Mitochondrion Oxidoreductase Peroxidase Phosphoprotein Reference proteome Selenocysteine | MCAARMAAAA | MCAARMAAAAQSVYSFSAHPLAGGEPVNLGSLRGKVLLIENVASLUGTTVRDYTQMNELQERLGPRALVVLGFPCNQFGHQENAKNEEILNSLKYVRPGGGFEPNFMLFQKCEVNGAKASPLFAFLREALPPPSDDPTALMTDPKFITWCPVCRNDVSWSFEKFLVGPDGVPVRRYSRRFPTIDIEPDIQALLSKGSGGA | arachidonic acid metabolic process lipoxygenase pathway response to oxidative stress cytosol; mitochondrion glutathione peroxidase activity phospholipid-hydroperoxide glutathione peroxidase activity Oryctolagus cuniculus Acetylation Cytoplasm Lipid metabolism Mitochondrion Oxidoreductase Peroxidase Phosphoprotein Refer... |
adaptive immune response B cell activation B cell differentiation B cell proliferation B cell receptor signaling pathway | B cell receptor complex; external side of plasma membrane; IgM B cell receptor complex; membrane raft; multivesicular body; plasma membrane | identical protein binding transmembrane signaling receptor activity | Mus musculus | 3D-structure Adaptive immunity Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Immunity Immunoglobulin domain Membrane Methylation Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix | MPGGLEALRA | MPGGLEALRALPLLLFLSYACLGPGCQALRVEGGPPSLTVNLGEEARLTCENNGRNPNITWWFSLQSNITWPPVPLGPGQGTTGQLFFPEVNKNHRGLYWCQVIENNILKRSCGTYLRVRNPVPRPFLDMGEGTKNRIITAEGIILLFCAVVPGTLLLFRKRWQNEKFGVDMPDDYEDENLYEGLNLDDCSMYEDISRGLQGTYQDVGNLHIGDAQLEKP | adaptive immune response B cell activation B cell differentiation B cell proliferation B cell receptor signaling pathway B cell receptor complex; external side of plasma membrane; IgM B cell receptor complex; membrane raft; multivesicular body; plasma membrane identical protein binding transmembrane signaling receptor ... |
adaptive immune response B cell activation B cell differentiation B cell proliferation B cell receptor signaling pathway | B cell receptor complex; external side of plasma membrane; IgM B cell receptor complex; membrane raft; multivesicular body; plasma membrane | identical protein binding transmembrane signaling receptor activity | Homo sapiens | 3D-structure Adaptive immunity Alternative splicing Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Immunity Immunoglobulin domain Membrane Methylation Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix | MPGGPGVLQA | MPGGPGVLQALPATIFLLFLLSAVYLGPGCQALWMHKVPASLMVSLGEDAHFQCPHNSSNNANVTWWRVLHGNYTWPPEFLGPGEDPNGTLIIQNVNKSHGGIYVCRVQEGNESYQQSCGTYLRVRQPPPRPFLDMGEGTKNRIITAEGIILLFCAVVPGTLLLFRKRWQNEKLGLDAGDEYEDENLYEGLNLDDCSMYEDISRGLQGTYQDVGSLNIGDVQLEKP | adaptive immune response B cell activation B cell differentiation B cell proliferation B cell receptor signaling pathway B cell receptor complex; external side of plasma membrane; IgM B cell receptor complex; membrane raft; multivesicular body; plasma membrane identical protein binding transmembrane signaling receptor ... |
protein processing involved in protein targeting to mitochondrion | mitochondrial inner membrane; mitochondrial processing peptidase complex; mitochondrion; respirasome | metal ion binding metalloendopeptidase activity | Neurospora crassa | Direct protein sequencing Electron transport Hydrolase Membrane Metal-binding Metalloprotease Mitochondrion Mitochondrion inner membrane Protease Reference proteome Respiratory chain Transit peptide Transport Zinc | MASRRLALNL | MASRRLALNLAQGVKARAGGVINPFRRGLATPHSGTGIKTQTTTLKNGLTVASQYSPYAQTSTVGMWIDAGSRAETDETNGTAHFLEHLAFKGTTKRTQQQLELEIENMGAHLNAYTSRENTVYFAKALNEDVPKCVDILQDILQNSKLEESAIERERDVILRESEEVEKQLEEVVFDHLHATAYQHQPLGRTILGPRENIRDITRTELVNYIKNNYTADRMVLVGAGGVPHEQLVEMADKYFSKLPATAPVSSASILSKKKPDFIGSDIRIRDDTIPTANIAIAVEGVSWSDDDYFTGLVTQAIVGNYDKALGNAPHQG... | protein processing involved in protein targeting to mitochondrion mitochondrial inner membrane; mitochondrial processing peptidase complex; mitochondrion; respirasome metal ion binding metalloendopeptidase activity Neurospora crassa Direct protein sequencing Electron transport Hydrolase Membrane Metal-binding Metallopr... |
protein processing involved in protein targeting to mitochondrion proteolysis | mitochondrial matrix; mitochondrial processing peptidase complex; mitochondrion | endopeptidase activator activity metal ion binding metalloendopeptidase activity | Saccharomyces cerevisiae | 3D-structure Direct protein sequencing Mitochondrion Reference proteome Transit peptide | MLRNGVQRLY | MLRNGVQRLYSNIARTDNFKLSSLANGLKVATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTEHVEGRAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQEQKLSAEYEIDEVWMKPELVLPELLHTAAYSGETLGSPLICPRELIPSISKYYLLDYRNKFYTPENTVAAFVGVPHEKALELTEKYLGDWQSTHPPITKKVAQYTGGESCIPPAPVFGNLPELFHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTHVLNQYYFVENCVAFN... | protein processing involved in protein targeting to mitochondrion proteolysis mitochondrial matrix; mitochondrial processing peptidase complex; mitochondrion endopeptidase activator activity metal ion binding metalloendopeptidase activity Saccharomyces cerevisiae 3D-structure Direct protein sequencing Mitochondrion Re... |
bile acid metabolic process cellular response to cholesterol fatty acid beta-oxidation intracellular cholesterol transport lipid hydroperoxide transport phospholipid transport positive regulation of apoptotic process positive regulation of cholesterol biosynthetic process positive regulation of cholesterol import posit... | cytoplasm; endoplasmic reticulum; mitochondrion; peroxisomal matrix; peroxisome; protein-containing complex | acetyl-CoA C-acyltransferase activity acetyl-CoA C-myristoyltransferase activity cholesterol binding cholesterol transfer activity fatty-acyl-CoA binding identical protein binding long-chain fatty acyl-CoA binding oleic acid binding phosphatidylcholine transfer activity phosphatidylethanolamine transfer activity propan... | Rattus norvegicus | Acetylation Acyltransferase Alternative initiation Cytoplasm Direct protein sequencing Lipid metabolism Lipid transport Lipid-binding Mitochondrion Peroxisome Phosphoprotein Reference proteome Transferase Transport | MPSVALNSPR | MPSVALNSPRLPRVFVVGVGMTKFMKPGGENSRDYPDLAKEAGQKALADRQIPYSAVEQACVGYVYGESTCGQRAIYHSLGLTGIPIINVNNNCSTGSTALFMAQQLVQGGLANCVLALGFEKMEKGSLGTKYSDRSNPLEKHIDVLINKYGMSACPFAPQLFGSAGKEHMETYGTKVEHFAKIGWKNHKHSVNNPYSQFQDEYSLDEIMKSRPVFDFLTVLQCCPTSDGAAAAIVSSEEFVQKHGLQSKAVEIVAQEMVTDMPSTFEEKSVIKMVGYDMSKEAARKCYEKSGLGPSDVDVIELHDCFSTNELLTYEALG... | bile acid metabolic process cellular response to cholesterol fatty acid beta-oxidation intracellular cholesterol transport lipid hydroperoxide transport phospholipid transport positive regulation of apoptotic process positive regulation of cholesterol biosynthetic process positive regulation of cholesterol import posit... |
cell population proliferation kidney development polyamine metabolic process positive regulation of cell population proliferation putrescine biosynthetic process from ornithine regulation of protein catabolic process response to virus | cytoplasm; cytosol | ornithine decarboxylase activity protein homodimerization activity | Homo sapiens | 3D-structure Decarboxylase Disease variant Hypotrichosis Lyase Phosphoprotein Polyamine biosynthesis Pyridoxal phosphate Reference proteome S-nitrosylation | MNNFGNEEFD | MNNFGNEEFDCHFLDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALPRVTPFYAVKCNDSKAIVKTLAATGTGFDCASKTEIQLVQSLGVPPERIIYANPCKQVSQIKYAANNGVQMMTFDSEVELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLRTSRLLLERAKELNIDVVGVSFHVGSGCTDPETFVQAISDARCVFDMGAEVGFSMYLLDIGGGFPGSEDVKLKFEEITGVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKIVLKEQTGSDDEDESSEQTFMYYVND... | cell population proliferation kidney development polyamine metabolic process positive regulation of cell population proliferation putrescine biosynthetic process from ornithine regulation of protein catabolic process response to virus cytoplasm; cytosol ornithine decarboxylase activity protein homodimerization activity... |
antiviral innate immune response cellular response to interferon-alpha cellular response to interferon-beta defense response to bacterium defense response to virus glucose homeostasis glucose metabolic process negative regulation of chemokine (C-X-C motif) ligand 2 production negative regulation of IP-10 production neg... | cytoplasm; cytosol; endoplasmic reticulum; membrane; mitochondrion; nucleoplasm; nucleus; ribosome | 2'-5'-oligoadenylate synthetase activity ATP binding double-stranded RNA binding metal ion binding | Mus musculus | Antiviral defense ATP-binding Cytoplasm Endoplasmic reticulum Immunity Innate immunity Lipoprotein Magnesium Metal-binding Microsome Mitochondrion Nucleotide-binding Nucleotidyltransferase Nucleus Prenylation Reference proteome RNA-binding Transferase | MEHGLRSIPA | MEHGLRSIPAWTLDKFIEDYLLPDTTFGADVKSAVNVVCDFLKERCFQGAAHPVRVSKVVKGGSSGKGTTLKGKSDADLVVFLNNLTSFEDQLNRRGEFIKEIKKQLYEVQHERRFRVKFEVQSSWWPNARSLSFKLSAPHLHQEVEFDVLPAFDVLGHVNTSSKPDPRIYAILIEECTSLGKDGEFSTCFTELQRNFLKQRPTKLKSLIRLVKHWYQLCKEKLGKPLPPQYALELLTVFAWEQGNGCYEFNTAQGFRTVLELVINYQHLRIYWTKYYDFQHQEVSKYLHRQLRKARPVILDPADPTGNVAGGNPEGWRR... | antiviral innate immune response cellular response to interferon-alpha cellular response to interferon-beta defense response to bacterium defense response to virus glucose homeostasis glucose metabolic process negative regulation of chemokine (C-X-C motif) ligand 2 production negative regulation of IP-10 production neg... |
microtubule anchoring at centrosome microtubule organizing center attachment site organization | centrosome; pericentriolar material | microtubule binding | Drosophila melanogaster | Developmental protein Phosphoprotein Reference proteome | MEVSADPYEQ | MEVSADPYEQKLYQMFRSCETQCGLLDEKSLLKLCSLLELRDQGSALIASLGGSHQLGVSFGQFKEALLNFLGSEFDERSLVITDEPLNNTYIESPPESSDREVSPKLVVGTKKYGRRSRPQQGIYELSVTDSDNTDEDQLQQQQNQRSLNGCDELGVQVQRSSSQSDLPGSRRLRSVHTSGSKLKRCASLPARRKMNSNTTGATTSPTAAAKLKQLSIQSQAQHSSSVESLDTVTPQQLETISVHSIMEAWELASIPNTRNLLHVLGFDEEEEVNLQQLTKALEEELRGIDGDHEQSNMLRALAALQATELGNYRLAYR... | microtubule anchoring at centrosome microtubule organizing center attachment site organization centrosome; pericentriolar material microtubule binding Drosophila melanogaster Developmental protein Phosphoprotein Reference proteome MEVSADPYEQ MEVSADPYEQKLYQMFRSCETQCGLLDEKSLLKLCSLLELRDQGSALIASLGGSHQLGVSFGQFKEALLNFLGSEFDE... |
butyryl-CoA catabolic process coenzyme A catabolic process malonyl-CoA catabolic process medium-chain fatty-acyl-CoA catabolic process propionyl-CoA metabolic process succinyl-CoA catabolic process | mitochondrion; peroxisome | coenzyme A diphosphatase activity magnesium ion binding | Mus musculus | Hydrolase Magnesium Manganese Metal-binding Peroxisome Reference proteome | MSSSSSWRRA | MSSSSSWRRAATVMLAAGWTHSSPAGFRLLLLQRAQNQRFLPGAHVFPGGVLDAADSSPDWVRLFAPRHTPPRFGLGPEPPRQPPFPGLSHGDADPAALPDDVALRICAIREAFEEAGVLLLRPRDAAPASQEPSQALSPPAGLAEWRSRVRSDPRCFLQLCAHLDCTPDIWALHDWGGWLTPYGRTIRRFDTTFFLCCLRDIPRVEPDVAEVVGYQWLSPSEATECFLSKEIWLAPPQFYEMRRLENFASLSALYRFCSDRPSEVPEKWLPIILLTSDGTIHLLPGDELYVKDSDFLEKNMSTDKKTEEIVKEGKVLNR... | butyryl-CoA catabolic process coenzyme A catabolic process malonyl-CoA catabolic process medium-chain fatty-acyl-CoA catabolic process propionyl-CoA metabolic process succinyl-CoA catabolic process mitochondrion; peroxisome coenzyme A diphosphatase activity magnesium ion binding Mus musculus Hydrolase Magnesium Mangane... |
apoptotic process DNA catabolic process neutrophil activation involved in immune response regulation of acute inflammatory response regulation of neutrophil mediated cytotoxicity | extracellular region; nuclear envelope; nucleus; zymogen granule | actin binding deoxyribonuclease I activity DNA binding | Sus scrofa | Actin-binding Apoptosis Calcium Cytoplasmic vesicle Direct protein sequencing Disulfide bond Endonuclease Glycoprotein Hydrolase Nuclease Nucleus Reference proteome Secreted Signal | MRAARLMGAL | MRAARLMGALLALAGLLQLALSLRIAAFNIRTFGETKMSNATLSNYIVRILSRYDIALIQEVRDSHLTAVGKLLNELNQDDPNNYHHVVSEPLGRSTYKERYLFVFRPDQVSVLDSYLYDDGCEPCGNDTFNREPSVVKFSSPSTQVKEFAIVPLHAAPSDAAAEIDSLYDVYLNVRQKWDLEDIMLMGDFNAGCSYVTTSHWSSIRLRESPPFQWLIPDTADTTVSSTHCAYDRIVVAGPLLQRAVVPDSAAPFDFQAAFGLSEQTALAISDHYPVEVTLKRA | apoptotic process DNA catabolic process neutrophil activation involved in immune response regulation of acute inflammatory response regulation of neutrophil mediated cytotoxicity extracellular region; nuclear envelope; nucleus; zymogen granule actin binding deoxyribonuclease I activity DNA binding Sus scrofa Actin-bind... |
establishment of protein localization to chromatin establishment of protein localization to telomere G-quadruplex DNA formation negative regulation of transcription by RNA polymerase II positive regulation of ribosomal protein gene transcription by RNA polymerase II positive regulation of transcription by RNA polymeras... | chromosome, telomeric region; cytosol; nuclear chromosome; nucleus; protein-DNA complex; shelterin complex; transcription regulator complex | cis-regulatory region sequence-specific DNA binding DNA binding, bending DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific double-stranded telomeric DNA binding G-quadruplex DNA binding histone binding nucleosomal DNA binding RNA polymerase II-specific DNA-b... | Saccharomyces cerevisiae | 3D-structure Activator Chromosome DNA-binding Nucleus Phosphoprotein Reference proteome Repressor Telomere Transcription Transcription regulation | MSSPDDFETA | MSSPDDFETAPAEYVDALDPSMVVVDSGSAAVTAPSDSAAEVKANQNEENTGATAAETSEKVDQTEVEKKDDDDTTEVGVTTTTPSIADTAATANIASTSGASVTEPTTDDTAADEKKEQVSGPPLSNMKFYLNRDADAHDSLNDIDQLARLIRANGGEVLDSKPRESKENVFIVSPYNHTNLPTVTPTYIKACCQSNSLLNMENYLVPYDNFREVVDSRLQEESHSNGVDNSNSNSDNKDSIRPKTEIISTNTNGATEDSTSEKVMVDAEQQARLQEQAQLLRQHVSSTASITSGGHNDLVQIEQPQKDTSNNNNSNVN... | establishment of protein localization to chromatin establishment of protein localization to telomere G-quadruplex DNA formation negative regulation of transcription by RNA polymerase II positive regulation of ribosomal protein gene transcription by RNA polymerase II positive regulation of transcription by RNA polymeras... |
cellular response to cadmium ion cellular response to calcium ion cellular response to extracellular stimulus cellular response to reactive oxygen species nervous system development osteoclast differentiation positive regulation of miRNA transcription positive regulation of osteoclast differentiation regulation of tran... | cytosol; endoplasmic reticulum; nucleoplasm; nucleus; protein-DNA complex; transcription factor AP-1 complex | chromatin binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific identical protein binding R-SMAD binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II core promoter sequence-specifi... | Gallus gallus | Cytoplasm DNA-binding Endoplasmic reticulum Nucleus Phosphoprotein Proto-oncogene Reference proteome | MMYQGFAGEY | MMYQGFAGEYEAPSSRCSSASPAGDSLTYYPSPADSFSSMGSPVNSQDFCTDLAVSSANFVPTVTAISTSPDLQWLVQPTLISSVAPSQNRGHPYGVPAPAPPAAYSRPAVLKAPGGRGQSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEEEKSALQAEIANLLKEKEKLEFILAAHRPACKMPEELRFSEELAAATALDLGAPSPAAAEEAFALPLMTEAPPAVPPKEPSGSGLELKAEPFDELLFSAGPREASRSVPDMDLPGASSFYASDWEPLGAGSGGELEPLCTPVVTCTPC... | cellular response to cadmium ion cellular response to calcium ion cellular response to extracellular stimulus cellular response to reactive oxygen species nervous system development osteoclast differentiation positive regulation of miRNA transcription positive regulation of osteoclast differentiation regulation of tran... |
CRD-mediated mRNA stabilization mRNA polyadenylation mRNA splicing, via spliceosome mRNA stabilization negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay nuclear-transcribed mRNA cata... | catalytic step 2 spliceosome; cell leading edge; cytoplasm; cytoplasmic ribonucleoprotein granule; cytoplasmic stress granule; cytosol; extracellular exosome; focal adhesion; lamellipodium; mCRD-mediated mRNA stability complex; membrane; nucleus; ribonucleoprotein complex | mRNA 3'-UTR binding mRNA binding poly(A) binding poly(U) RNA binding RNA binding translation activator activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Cell projection Cytoplasm Direct protein sequencing Host-virus interaction Methylation mRNA processing mRNA splicing Nonsense-mediated mRNA decay Nucleus Phosphoprotein Reference proteome Repeat RNA-binding Spliceosome | MNPSAPSYPM | MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTI... | CRD-mediated mRNA stabilization mRNA polyadenylation mRNA splicing, via spliceosome mRNA stabilization negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay nuclear-transcribed mRNA cata... |
defense response to bacterium killing of cells of another organism metabolic process | extracellular space | lysozyme activity | Oncorhynchus mykiss | 3D-structure Antibiotic Antimicrobial Bacteriolytic enzyme Direct protein sequencing Disulfide bond Glycosidase Hydrolase Secreted Signal | MRAVVVLLLV | MRAVVVLLLVAVASAKVYDRCELARALKASGMDGYAGNSLPNWVCLSKWESSYNTQATNRNTDGSTDYGIFQINSRYWCDDGRTPGAKNVCGIRCSQLLTADLTVAIRCAKRVVLDPNGIGAWVAWRLHCQNQDLRSYVAGCGV | defense response to bacterium killing of cells of another organism metabolic process extracellular space lysozyme activity Oncorhynchus mykiss 3D-structure Antibiotic Antimicrobial Bacteriolytic enzyme Direct protein sequencing Disulfide bond Glycosidase Hydrolase Secreted Signal MRAVVVLLLV MRAVVVLLLVAVASAKVYDRCELARAL... |
adaptive immune response cell surface receptor signaling pathway establishment or maintenance of cell polarity positive thymic T cell selection protein transport regulation of lymphocyte apoptotic process | alpha-beta T cell receptor complex; cytosol; external side of plasma membrane; plasma membrane | identical protein binding transmembrane signaling receptor activity | Mus musculus | 3D-structure Adaptive immunity Disulfide bond Glycoprotein Immunity Immunoglobulin domain Membrane Phosphoprotein Receptor Reference proteome Signal Transmembrane Transmembrane helix | MEQRKGLAGL | MEQRKGLAGLFLVISLLQGTVAQTNKAKNLVQVDGSRGDGSVLLTCGLTDKTIKWLKDGSIISPLNATKNTWNLGNNAKDPRGTYQCQGAKETSNPLQVYYRMCENCIELNIGTISGFIFAEVISIFFLALGVYLIAGQDGVRQSRASDKQTLLQNEQLYQPLKDREYDQYSHLQGNQLRKK | adaptive immune response cell surface receptor signaling pathway establishment or maintenance of cell polarity positive thymic T cell selection protein transport regulation of lymphocyte apoptotic process alpha-beta T cell receptor complex; cytosol; external side of plasma membrane; plasma membrane identical protein bi... |
iron-sulfur cluster assembly lipoate biosynthetic process | mitochondrial iron-sulfur cluster assembly complex; mitochondrion; respirasome | acyl binding acyl carrier activity | Neurospora crassa | Direct protein sequencing Electron transport Fatty acid biosynthesis Fatty acid metabolism Lipid biosynthesis Lipid metabolism Mitochondrion Phosphopantetheine Phosphoprotein Reference proteome Respiratory chain Transit peptide Transport | MFRTAALTAA | MFRTAALTAARVARPAVASAVRAGVARPAFVQAVPKVAAFQAVRFYSAGGHLKKDEVFSRIAQVLSGFDKVNDPKNITETAHFANDLGLDSLDTVEVVMAIEEEFSIEIPDKDADQIHSVDKAVEYILSQPDAN | iron-sulfur cluster assembly lipoate biosynthetic process mitochondrial iron-sulfur cluster assembly complex; mitochondrion; respirasome acyl binding acyl carrier activity Neurospora crassa Direct protein sequencing Electron transport Fatty acid biosynthesis Fatty acid metabolism Lipid biosynthesis Lipid metabolism Mit... |
glycolytic process | cytoplasm | dihydrolipoyllysine-residue acetyltransferase activity | Geobacillus stearothermophilus | 3D-structure Acyltransferase Direct protein sequencing Glycolysis Lipoyl Transferase | MAFEFKLPDI | MAFEFKLPDIGEGIHEGEIVKWFVKPGDEVNEDDVLCEVQNDKAVVEIPSPVKGKVLEILVPEGTVATVGQTLITLDAPGYENMTFKGQEQEEAKKEEKTETVSKEEKVDAVAPNAPAAEAEAGPNRRVIAMPSVRKYAREKGVDIRLVQGTGKNGRVLKEDIDAFLAGGAKPAPAAAEEKAAPAAAKPATTEGEFPETREKMSGIRRAIAKAMVHSKHTAPHVTLMDEADVTKLVAHRKKFKAIAAEKGIKLTFLPYVVKALVSALREYPVLNTSIDDETEEIIQKHYYNIGIAADTDRGLLVPVIKHADRKPIFALAQ... | glycolytic process cytoplasm dihydrolipoyllysine-residue acetyltransferase activity Geobacillus stearothermophilus 3D-structure Acyltransferase Direct protein sequencing Glycolysis Lipoyl Transferase MAFEFKLPDI MAFEFKLPDIGEGIHEGEIVKWFVKPGDEVNEDDVLCEVQNDKAVVEIPSPVKGKVLEILVPEGTVATVGQTLITLDAPGYENMTFKGQEQEEAKKEEKTETVSKEEKV... |
cellular response to hormone stimulus developmental growth follicle-stimulating hormone secretion G protein-coupled receptor signaling pathway gonad development luteinizing hormone secretion negative regulation of organ growth organ growth positive regulation of steroid biosynthetic process regulation of signaling rece... | extracellular space; follicle-stimulating hormone complex; pituitary gonadotropin complex | follicle-stimulating hormone activity hormone activity | Rattus norvegicus | Disulfide bond Glycoprotein Hormone Reference proteome Secreted Signal | MDCYRRYAAV | MDCYRRYAAVILVMLSMVLHILHSLPDGDLIIQGCPECKLKENKYFSKLGAPIYQCMGCCFSRAYPTPARSKKTMLVPKNITSEATCCVAKSFTKATVMGNARVENHTDCHCSTCYYHKS | cellular response to hormone stimulus developmental growth follicle-stimulating hormone secretion G protein-coupled receptor signaling pathway gonad development luteinizing hormone secretion negative regulation of organ growth organ growth positive regulation of steroid biosynthetic process regulation of signaling rece... |
cellular response to pheromone intracellular signal transduction negative regulation of signal transduction signal transduction | plasma membrane | GTPase activator activity | Saccharomyces cerevisiae | Pheromone response Phosphoprotein Reference proteome Signal transduction inhibitor | MVDKNRTLHE | MVDKNRTLHELSSKNFSRTPNGLIFTNDLKTVYSIFLICLDLKEKKHSSDTKSFLLTAFTKHFHFTFTYQEAIKAMGQLELKVDMNTTCINVSYNIKPSLARHLLTLFMSSKLLHTPQDRTRGEPKEKVLFQPTPKGVAVLQKYVRDIGLKTMPDILLSSFNSMKLFTFERSSVTDSIIHSDYLIHILFIKMMGAKPNVWSPTNADDPLPCLSSLLEYTNNDDTFTFEKSKPEQGWQAQIGNIDINDLERVSPLAHRFFTNPDSESHTQYYVSNAGIRLFENKTFGTSKKIVIKYTFTTKAIWQWIMDCTDIMHVKEAVS... | cellular response to pheromone intracellular signal transduction negative regulation of signal transduction signal transduction plasma membrane GTPase activator activity Saccharomyces cerevisiae Pheromone response Phosphoprotein Reference proteome Signal transduction inhibitor MVDKNRTLHE MVDKNRTLHELSSKNFSRTPNGLIFTNDLK... |
phosphorylation positive regulation of cytoplasmic translation positive regulation of sprouting angiogenesis | nucleus; rough endoplasmic reticulum | ATP binding magnesium ion binding mRNA binding potassium ion binding protein tyrosine kinase activity pyruvate kinase activity | Oryctolagus cuniculus | 3D-structure Acetylation Allosteric enzyme Alternative splicing ATP-binding Cytoplasm Direct protein sequencing Glycolysis Isopeptide bond Kinase Magnesium Metal-binding Methylation Nucleotide-binding Nucleus Phosphoprotein Potassium Pyruvate Reference proteome Transferase Translation regulation Ubl conjugation | MSKSHSEAGS | MSKSHSEAGSAFIQTQQLHAAMADTFLEHMCRLDIDSAPITARNTGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVDVGSKVYVDDGLISLQVKQKGPDFLVTEVENGGFLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKILGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRA... | phosphorylation positive regulation of cytoplasmic translation positive regulation of sprouting angiogenesis nucleus; rough endoplasmic reticulum ATP binding magnesium ion binding mRNA binding potassium ion binding protein tyrosine kinase activity pyruvate kinase activity Oryctolagus cuniculus 3D-structure Acetylation ... |
cellular response to insulin stimulus glycolytic process phosphorylation positive regulation of cytoplasmic translation positive regulation of sprouting angiogenesis | cytoplasm; nucleus; rough endoplasmic reticulum | ATP binding magnesium ion binding mRNA binding potassium ion binding protein tyrosine kinase activity pyruvate kinase activity | Felis catus | 3D-structure Acetylation Allosteric enzyme Alternative splicing ATP-binding Cytoplasm Direct protein sequencing Glycolysis Isopeptide bond Kinase Magnesium Metal-binding Methylation Nucleotide-binding Nucleus Phosphoprotein Potassium Pyruvate Reference proteome Transferase Translation regulation Ubl conjugation | MSKPHSDVGT | MSKPHSDVGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVEILKEMIKSGMNVARLNFSHGTHEYHAETIKNVRAATESFASDPIRYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENVLWLDYKNICKVVEVGSKVYVDDGLISLLVKEKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRA... | cellular response to insulin stimulus glycolytic process phosphorylation positive regulation of cytoplasmic translation positive regulation of sprouting angiogenesis cytoplasm; nucleus; rough endoplasmic reticulum ATP binding magnesium ion binding mRNA binding potassium ion binding protein tyrosine kinase activity pyru... |
animal organ regeneration canonical glycolysis cellular response to insulin stimulus glucose metabolic process glycolytic process liver development phosphorylation positive regulation of cytoplasmic translation positive regulation of sprouting angiogenesis programmed cell death protein homotetramerization protein tetra... | cilium; cytoplasm; cytosol; nucleus; pyruvate kinase complex; rough endoplasmic reticulum | ADP binding ATP binding identical protein binding magnesium ion binding mRNA binding potassium ion binding protein dimerization activity protein tyrosine kinase activity pyruvate kinase activity thyroid hormone binding | Rattus norvegicus | Acetylation Allosteric enzyme Alternative splicing ATP-binding Cytoplasm Direct protein sequencing Glycolysis Hydroxylation Isopeptide bond Kinase Magnesium Metal-binding Methylation Nucleotide-binding Nucleus Phosphoprotein Potassium Pyruvate Reference proteome Transferase Translation regulation Ubl conjugation | MPKPDSEAGT | MPKPDSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSAPITARNTGIICTIGPASRSVEMLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRAATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKEKGADYLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRA... | animal organ regeneration canonical glycolysis cellular response to insulin stimulus glucose metabolic process glycolytic process liver development phosphorylation positive regulation of cytoplasmic translation positive regulation of sprouting angiogenesis programmed cell death protein homotetramerization protein tetra... |
binding of sperm to zona pellucida chaperone-mediated protein folding positive regulation of establishment of protein localization to telomere positive regulation of telomerase RNA localization to Cajal body positive regulation of telomere maintenance via telomerase protein folding protein stabilization scaRNA localiza... | acrosomal vesicle; cell body; centrosome; chaperonin-containing T-complex; Golgi apparatus; heterochromatin; microtubule; microtubule organizing center; myelin sheath; pericentriolar material; zona pellucida receptor complex | ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone protein folding chaperone ubiquitin protein ligase binding unfolded protein binding | Mus musculus | Acetylation Alternative splicing ATP-binding Chaperone Cytoplasm Cytoskeleton Direct protein sequencing Nucleotide-binding Phosphoprotein Reference proteome | MEGPLSVFGD | MEGPLSVFGDRSTGEAVRSQNVMAAASIANIVKSSFGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIINTDELGRDCLINAAKTSMSSKIIGINGDYFANMVVDAVLAVKYTDARGQPRYPVNSVNILKAHGRSQIESMLINGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMYLKYFVEAGAMAVRRVLKRDLKHVA... | binding of sperm to zona pellucida chaperone-mediated protein folding positive regulation of establishment of protein localization to telomere positive regulation of telomerase RNA localization to Cajal body positive regulation of telomere maintenance via telomerase protein folding protein stabilization scaRNA localiza... |
microtubule-based movement | cytoplasm; cytoplasmic dynein complex; cytosol; membrane; microtubule; sperm flagellum | dynein intermediate chain binding | Mus musculus | Alternative splicing Cytoplasm Cytoskeleton Disease variant Dynein Membrane Microtubule Motor protein Reference proteome Transport | MERRGRMAKT | MERRGRMAKTPTGQTHQSPVSKRERKPSMFEKESYAQILRERLRESFHDVQYVEPPFDDSIADVGKEWKSALAKLKFANSYRMEPLKKFQAHLVETKIQQILKDSLKDVKYDDKAPHLSLELADGILAAVKEFAYHRYKFIIQVLFIQKTGQAINIASRWIWDVAWDNWVEAKHETESYVVLALVFALYCE | microtubule-based movement cytoplasm; cytoplasmic dynein complex; cytosol; membrane; microtubule; sperm flagellum dynein intermediate chain binding Mus musculus Alternative splicing Cytoplasm Cytoskeleton Disease variant Dynein Membrane Microtubule Motor protein Reference proteome Transport MERRGRMAKT MERRGRMAKTPTGQTHQ... |
inositol biosynthetic process phospholipid biosynthetic process | cytoplasm | inositol-3-phosphate synthase activity | Saccharomyces cerevisiae | 3D-structure Cytoplasm Direct protein sequencing Inositol biosynthesis Isomerase Lipid biosynthesis Lipid metabolism NAD Phospholipid biosynthesis Phospholipid metabolism Phosphoprotein Reference proteome | MTEDNIAPIT | MTEDNIAPITSVKVVTDKCTYKDNELLTKYSYENAVVTKTASGRFDVTPTVQDYVFKLDLKKPEKLGIMLIGLGGNNGSTLVASVLANKHNVEFQTKEGVKQPNYFGSMTQCSTLKLGIDAEGNDVYAPFNSLLPMVSPNDFVVSGWDINNADLYEAMQRSQVLEYDLQQRLKAKMSLVKPLPSIYYPDFIAANQDERANNCINLDEKGNVTTRGKWTHLQRIRRDIQNFKEENALDKVIVLWTANTERYVEVSPGVNDTMENLLQSIKNDHEEIAPSTIFAAASILEGVPYINGSPQNTFVPGLVQLAEHEGTFIAGDD... | inositol biosynthetic process phospholipid biosynthetic process cytoplasm inositol-3-phosphate synthase activity Saccharomyces cerevisiae 3D-structure Cytoplasm Direct protein sequencing Inositol biosynthesis Isomerase Lipid biosynthesis Lipid metabolism NAD Phospholipid biosynthesis Phospholipid metabolism Phosphopro... |
riboflavin biosynthetic process | cytosol; riboflavin synthase complex | 6,7-dimethyl-8-ribityllumazine synthase activity | Bacillus subtilis | 3D-structure Direct protein sequencing Reference proteome Riboflavin biosynthesis Transferase | MNIIQGNLVG | MNIIQGNLVGTGLKIGIVVGRFNDFITSKLLSGAEDALLRHGVDTNDIDVAWVPGAFEIPFAAKKMAETKKYDAIITLGTVIRGATTHYDYVCNEAAKGIAQAANTTGVPVIFGIVTTENIEQAIERAGTKAGNKGVDCAVSAIEMANLNRSFE | riboflavin biosynthetic process cytosol; riboflavin synthase complex 6,7-dimethyl-8-ribityllumazine synthase activity Bacillus subtilis 3D-structure Direct protein sequencing Reference proteome Riboflavin biosynthesis Transferase MNIIQGNLVG MNIIQGNLVGTGLKIGIVVGRFNDFITSKLLSGAEDALLRHGVDTNDIDVAWVPGAFEIPFAAKKMAETKKYDAIITLG... |
base-excision repair cell division DNA biosynthetic process DNA ligation DNA recombination DNA repair lagging strand elongation mitochondrial DNA metabolic process nucleotide-excision repair Okazaki fragment processing involved in mitotic DNA replication | mitochondrion; nuclear replication fork; nucleus | ATP binding DNA binding DNA ligase (ATP) activity DNA ligase activity metal ion binding | Schizosaccharomyces pombe | ATP-binding Cell cycle Cell division DNA damage DNA recombination DNA repair DNA replication Ligase Magnesium Metal-binding Nucleotide-binding Nucleus Reference proteome | MRTVFSQIPR | MRTVFSQIPRFKQVNQYIRMSTRQSDISNFFISSASHKSEHVEVSQSSSDSKNVDGRSTSEKRKVESVKLVDESKHNNHDDTGTQNVERENNIVSEAKKQKTLGSSSSSSDAVSSNNDSGASTPIPLPIKEPPLESNARNDKLKGHATFAEMVKAFTKIENTSKRLEIIDIMGTYFFGILRDHPSDLLACVYLSINKLGPDYSGLELGIGESIIMKAIGESTGQTLQQIKLSFHKVGDLGLVAQTSRQNQPTMFKPAALTIPFLFDSLKKIAQMSGNQSQNRKIGVIKRLLSSCEGAEPKYLIRALEGKLRLQLAEKTIL... | base-excision repair cell division DNA biosynthetic process DNA ligation DNA recombination DNA repair lagging strand elongation mitochondrial DNA metabolic process nucleotide-excision repair Okazaki fragment processing involved in mitotic DNA replication mitochondrion; nuclear replication fork; nucleus ATP binding DNA ... |
base-excision repair, gap-filling cellular response to hydrogen peroxide cellular response to UV cellular response to xenobiotic stimulus epithelial cell differentiation estrous cycle heart development leading strand elongation liver regeneration mismatch repair mitotic telomere maintenance via semi-conservative replic... | centrosome; chromatin; chromosome, telomeric region; cyclin-dependent protein kinase holoenzyme complex; extracellular exosome; male germ cell nucleus; nuclear body; nuclear lamina; nuclear replication fork; nucleoplasm; nucleus; PCNA complex; PCNA-p21 complex; replication fork; replisome | chromatin binding damaged DNA binding dinucleotide insertion or deletion binding DNA polymerase binding DNA polymerase processivity factor activity enzyme binding histone acetyltransferase binding identical protein binding MutLalpha complex binding nuclear estrogen receptor binding protein-containing complex binding pu... | Homo sapiens | 3D-structure Acetylation Deafness Direct protein sequencing Disease variant DNA damage DNA repair DNA replication DNA-binding Dwarfism Host-virus interaction Isopeptide bond Methylation Neurodegeneration Nucleus Phosphoprotein Reference proteome Ubl conjugation | MFEARLVQGS | MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLKYYLAPKIEDEEGS | base-excision repair, gap-filling cellular response to hydrogen peroxide cellular response to UV cellular response to xenobiotic stimulus epithelial cell differentiation estrous cycle heart development leading strand elongation liver regeneration mismatch repair mitotic telomere maintenance via semi-conservative replic... |
branched-chain amino acid catabolic process fatty acid beta-oxidation using acyl-CoA dehydrogenase leucine catabolic process leucine metabolic process | mitochondrial matrix; mitochondrial membrane; mitochondrion; nucleoplasm | butyryl-CoA dehydrogenase activity flavin adenine dinucleotide binding identical protein binding isovaleryl-CoA dehydrogenase activity | Rattus norvegicus | Acetylation Direct protein sequencing FAD Flavoprotein Mitochondrion Oxidoreductase Reference proteome Transit peptide | MATAVRLLGR | MATAVRLLGRRVSSWRLRPLPSPLAVPQRAHSMLPVDDDINGLNEEQKQLRHTISKFVQENLAPKAQEIDQSNDFKNLREFWKQLGSLGVLGITAPVQYGGSGLGYLEHVLVMEEISRASAAVGLSYGAHSNLCINQIVRNGNEAQKEKYLPKLISGEFIGALAMSEPNAGSDVVSMRLKAEKKGDHYVLNGNKFWITNGPDADVLVVYAKTDLTAVPASRGITAFIVEKDMPGFSTSKKLDKLGMRGSNTCELVFEDCKVPAANILSQESKGVYVLMSGLDLERLVLAGGPLGIMQAVLDHTIPYLHVREAFGQKIGQF... | branched-chain amino acid catabolic process fatty acid beta-oxidation using acyl-CoA dehydrogenase leucine catabolic process leucine metabolic process mitochondrial matrix; mitochondrial membrane; mitochondrion; nucleoplasm butyryl-CoA dehydrogenase activity flavin adenine dinucleotide binding identical protein binding... |
amino acid biosynthetic process aromatic amino acid family biosynthetic process chorismate biosynthetic process | cytosol | chorismate synthase activity FMN binding identical protein binding | Escherichia coli | Amino-acid biosynthesis Aromatic amino acid biosynthesis Direct protein sequencing FAD Flavoprotein FMN Lyase NADP Reference proteome | MAGNTIGQLF | MAGNTIGQLFRVTTFGESHGLALGCIVDGVPPGIPLTEADLQHDLDRRRPGTSRYTTQRREPDQVKILSGVFEGVTTGTSIGLLIENTDQRSQDYSAIKDVFRPGHADYTYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGIEIRGCLTQMGDIPLDIKDWSQVEQNPFFCPDPDKIDALDELMRALKKEGDSIGAKVTVVASGVPAGLGEPVFDRLDADIAHALMSINAVKGVEIGDGFDVVALRGSQNRDEITKDGFQSNHAGGILGGISSGQQIIAHMALKPTSSITVPGRTINRFGEEVEMITKGRH... | amino acid biosynthetic process aromatic amino acid family biosynthetic process chorismate biosynthetic process cytosol chorismate synthase activity FMN binding identical protein binding Escherichia coli Amino-acid biosynthesis Aromatic amino acid biosynthesis Direct protein sequencing FAD Flavoprotein FMN Lyase NADP R... |
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway aggregation involved in sorocarp development cAMP catabolic process extracellular regulation of signal transduction negative regulation of glucose mediated signaling pathway response to cAMP response to catechin response to differentiation-induci... | cell surface; endoplasmic reticulum; extracellular region; plasma membrane | 3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-GMP phosphodiesterase activity 3',5'-cyclic-nucleotide phosphodiesterase activity cAMP binding cGMP binding | Dictyostelium discoideum | cAMP cAMP-binding cGMP cGMP-binding Glycoprotein Hydrolase Nucleotide-binding Reference proteome Secreted Signal Zinc | MALNKKLISL | MALNKKLISLLLLIFIILNIVNSHQQEDCDDDDEDIGISAERSERRSVKNSNDGSNFYNLNDYYTPENWNYYSGSFATKDCRDASYITIPLGTTGGLDEGNLSSFLLTKKGSNLFIALDAGTVWQGVRRLTTFKYFNTLFNITYPSWAVLPEQRTSWFLKNHVMSYFIGHSHLDHVGGLILVSPEDYLAKNWIDVQPPINNGIMGLIRKLGFKPTDFTSSSILQKKTIMGLPSTINSISTNLFNNQVWPNLPSFGRYQYFSLASGIEYPFTELVPYNATTMSLVANEFPFSVKVKPFELCHDNLISTSFLFTDSISGEQI... | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway aggregation involved in sorocarp development cAMP catabolic process extracellular regulation of signal transduction negative regulation of glucose mediated signaling pathway response to cAMP response to catechin response to differentiation-induci... |
defense response to bacterium fatty acid metabolic process | endoplasmic reticulum; Golgi apparatus | fatty-acyl-CoA binding | Sus scrofa | Acetylation Antibiotic Antimicrobial Direct protein sequencing Endoplasmic reticulum Golgi apparatus Hydroxylation Lipid-binding Phosphoprotein Reference proteome Transport | MSQAEFEKAA | MSQAEFEKAAEEVKNLKTKPADDEMLFIYSHYKQATVGDINTERPGILDLKGKAKWDAWNGLKGTSKEDAMKAYINKVEELKKKYGI | defense response to bacterium fatty acid metabolic process endoplasmic reticulum; Golgi apparatus fatty-acyl-CoA binding Sus scrofa Acetylation Antibiotic Antimicrobial Direct protein sequencing Endoplasmic reticulum Golgi apparatus Hydroxylation Lipid-binding Phosphoprotein Reference proteome Transport MSQAEFEKAA MSQA... |
cartilage development cellular response to UV-A connective tissue replacement involved in inflammatory response wound healing negative regulation of apoptotic process negative regulation of catalytic activity negative regulation of endopeptidase activity negative regulation of membrane protein ectodomain proteolysis ne... | basement membrane; extracellular matrix; extracellular space | cytokine activity growth factor activity metalloendopeptidase inhibitor activity peptidase inhibitor activity protease binding zinc ion binding | Mus musculus | Disulfide bond Glycoprotein Growth factor Metal-binding Metalloenzyme inhibitor Metalloprotease inhibitor Phosphoprotein Protease inhibitor Reference proteome Secreted Signal Zinc | MMAPFASLAS | MMAPFASLASGILLLLSLIASSKACSCAPPHPQTAFCNSDLVIRAKFMGSPEINETTLYQRYKIKMTKMLKGFKAVGNAADIRYAYTPVMESLCGYAHKSQNRSEEFLITGRLRNGNLHISACSFLVPWRTLSPAQQRAFSKTYSAGCGVCTVFPCLSIPCKLESDTHCLWTDQVLVGSEDYQSRHFACLPRNPGLCTWRSLGAR | cartilage development cellular response to UV-A connective tissue replacement involved in inflammatory response wound healing negative regulation of apoptotic process negative regulation of catalytic activity negative regulation of endopeptidase activity negative regulation of membrane protein ectodomain proteolysis ne... |
animal organ morphogenesis cell differentiation cell-cell signaling fibroblast growth factor receptor signaling pathway glial cell differentiation nervous system development positive regulation of cell division positive regulation of cell population proliferation positive regulation of gene expression positive regulati... | cytoplasm; extracellular region; extracellular space | fibroblast growth factor receptor binding growth factor activity | Homo sapiens | Alternative splicing Disease variant Glycoprotein Growth factor Mitogen Proto-oncogene Reference proteome Secreted Signal | MSLSFLLLLF | MSLSFLLLLFFSHLILSAWAHGEKRLAPKGQPGPAATDRNPRGSSSRQSSSSAMSSSSASSSPAASLGSQGSGLEQSSFQWSPSGRRTGSLYCRVGIGFHLQIYPDGKVNGSHEANMLSVLEIFAVSQGIVGIRGVFSNKFLAMSKKGKLHASAKFTDDCKFRERFQENSYNTYASAIHRTEKTGREWYVALNKRGKAKRGCSPRVKPQHISTHFLPRFKQSEQPELSFTVTVPEKKKPPSPIKPKIPLSAPRKNTNSVKYRLKFRFG | animal organ morphogenesis cell differentiation cell-cell signaling fibroblast growth factor receptor signaling pathway glial cell differentiation nervous system development positive regulation of cell division positive regulation of cell population proliferation positive regulation of gene expression positive regulati... |
epithelial cell differentiation intermediate filament cytoskeleton organization intermediate filament organization keratinization | cytosol; extracellular exosome; intermediate filament; keratin filament | structural constituent of skin epidermis | Homo sapiens | Coiled coil Corneal dystrophy Disease variant Intermediate filament Keratin Methylation Phosphoprotein Reference proteome | MSRQASKTSG | MSRQASKTSGGGSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFGGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSSISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAAENEFVTLKKDVDSAYMNKVE... | epithelial cell differentiation intermediate filament cytoskeleton organization intermediate filament organization keratinization cytosol; extracellular exosome; intermediate filament; keratin filament structural constituent of skin epidermis Homo sapiens Coiled coil Corneal dystrophy Disease variant Intermediate filam... |
de novo' IMP biosynthetic process glutamine metabolic process | cytoplasm | ATP binding glutaminase activity phosphoribosylformylglycinamidine synthase activity | Bacillus subtilis | ATP-binding Cytoplasm Glutamine amidotransferase Hydrolase Ligase Nucleotide-binding Purine biosynthesis Reference proteome | MKFAVIVLPG | MKFAVIVLPGSNCDIDMYHAVKDELGHEVEYVWHEETSLDGFDGVLIPGGFSYGDYLRCGAIARFANIMPAVKQAAAEGKPVLGVCNGFQILQELGLLPGAMRRNKDLKFICRPVELIVQNDETLFTASYEKGESITIPVAHGEGNFYCDDETLATLKENNQIAFTYGSNINGSVSDIAGVVNEKGNVLGMMPHPERAVDELLGSADGLKLFQSIVKNWRETHVTTA | de novo' IMP biosynthetic process glutamine metabolic process cytoplasm ATP binding glutaminase activity phosphoribosylformylglycinamidine synthase activity Bacillus subtilis ATP-binding Cytoplasm Glutamine amidotransferase Hydrolase Ligase Nucleotide-binding Purine biosynthesis Reference proteome MKFAVIVLPG MKFAVIVLPG... |
de novo' IMP biosynthetic process purine nucleotide biosynthetic process | cytoplasm | ATP binding glutaminase activity magnesium ion binding phosphoribosylformylglycinamidine synthase activity | Bacillus subtilis | ATP-binding Cytoplasm Direct protein sequencing Ligase Magnesium Metal-binding Nucleotide-binding Purine biosynthesis Reference proteome | MSLLLEPSKE | MSLLLEPSKEQIKEEKLYQQMGVSDDEFALIESILGRLPNYTEIGIFSVMWSEHCSYKNSKPILRKFPTSGERVLQGPGEGAGIVDIGDNQAVVFKIESHNHPSALEPYQGAATGVGGIIRDVFSMGARPIAVLNSLRFGELTSPRVKYLFEEVVAGIAGYGNCIGIPTVGGEVQFDSSYEGNPLVNAMCVGLINHEDIKKGQAKGVGNTVMYVGAKTGRDGIHGATFASEEMSDSSEEKRSAVQVGDPFMEKLLLEACLEVIQCDALVGIQDMGAAGLTSSSAEMASKAGSGIEMNLDLIPQRETGMTAYEMMLSESQE... | de novo' IMP biosynthetic process purine nucleotide biosynthetic process cytoplasm ATP binding glutaminase activity magnesium ion binding phosphoribosylformylglycinamidine synthase activity Bacillus subtilis ATP-binding Cytoplasm Direct protein sequencing Ligase Magnesium Metal-binding Nucleotide-binding Purine biosynt... |
de novo' AMP biosynthetic process 'de novo' IMP biosynthetic process AMP biosynthetic process | cytosol | (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity | Bacillus subtilis | 3D-structure Direct protein sequencing Lyase Purine biosynthesis Reference proteome | MIERYSRPEM | MIERYSRPEMSAIWTDENRFQAWLEVEILACEAWAELGVIPKEDVKVMRENASFDINRILEIEKDTRHDVVAFTRAVSESLGEERKWVHYGLTSTDVVDTALSYLLKQANDILLKDLERFVDIIKEKAKEHKYTVMMGRTHGVHAEPTTFGLKLALWHEEMKRNLERFKQAKAGIEVGKISGAVGTYANIDPFVEQYVCEKLGLKAAPISTQTLQRDRHADYMATLALIATSIEKFAVEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSENMTGMARVIRGYMMTAYENVPLWHERDISHSSAERIILPDATIAL... | de novo' AMP biosynthetic process 'de novo' IMP biosynthetic process AMP biosynthetic process cytosol (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity Bacillus subtilis 3D-structure Direct protein ... |
Group I intron splicing mRNA processing positive regulation of RNA splicing RNA folding tRNA aminoacylation tyrosyl-tRNA aminoacylation | cytosol; mitochondrial matrix; mitochondrion | ATP binding identical protein binding RNA binding tyrosine-tRNA ligase activity | Neurospora crassa | 3D-structure Aminoacyl-tRNA synthetase ATP-binding Ligase Mitochondrion mRNA processing Nucleotide-binding Protein biosynthesis Reference proteome Transit peptide | MLLRTKALIR | MLLRTKALIRSGGSIAKYAAANPSCFILQRRGLRREFGPKYTAKINEAEENWQARAEAIKKGKKQNTWDLFEERGYVKDTAGTKEHIAELMRTRRIGAYVGIDPTAPSLHVGHLLPLMPLFWMYLEGYKAFTLIGGSTAKIGDPTGRLKSRDHLSSSDATMNMTKIHYQLKKLWENVDTQMRARGYEADWARKRGIVNNNHWWNKQPMLEVLRRVGHALRIGPMLSRDTVKNKMTQGDGVSFAEFTYPIMQGWDWFELFYQQGVQMQIGGSDQYGNIISGLEVVKAARESEPDPQERKYVTPKTALDECVGFTVPLLTDS... | Group I intron splicing mRNA processing positive regulation of RNA splicing RNA folding tRNA aminoacylation tyrosyl-tRNA aminoacylation cytosol; mitochondrial matrix; mitochondrion ATP binding identical protein binding RNA binding tyrosine-tRNA ligase activity Neurospora crassa 3D-structure Aminoacyl-tRNA synthetase AT... |
cellular respiration generation of precursor metabolites and energy mitochondrial electron transport, cytochrome c to oxygen | mitochondrial inner membrane; mitochondrial membrane; mitochondrial respiratory chain complex IV; mitochondrion | enzyme regulator activity oxidoreductase activity | Homo sapiens | 3D-structure Charcot-Marie-Tooth disease Direct protein sequencing Membrane Mitochondrion Mitochondrion inner membrane Neurodegeneration Neuropathy Oxidoreductase Reference proteome Transit peptide Transmembrane Transmembrane helix | MAVVGVSSVS | MAVVGVSSVSRLLGRSRPQLGRPMSSGAHGEEGSARMWKTLTFFVALPGVAVSMLNVYLKSHHGEHERPEFIAYPHLRIRTKPFPWGDGNHTLFHNPHVNPLPTGYEDE | cellular respiration generation of precursor metabolites and energy mitochondrial electron transport, cytochrome c to oxygen mitochondrial inner membrane; mitochondrial membrane; mitochondrial respiratory chain complex IV; mitochondrion enzyme regulator activity oxidoreductase activity Homo sapiens 3D-structure Charcot... |
histidyl-tRNA aminoacylation mitochondrial translation translation tRNA aminoacylation for protein translation | cytoplasm; cytosol; mitochondrion | ATP binding histidine-tRNA ligase activity identical protein binding protein homodimerization activity RNA binding | Homo sapiens | 3D-structure Acetylation Alternative splicing Aminoacyl-tRNA synthetase ATP-binding Charcot-Marie-Tooth disease Cytoplasm Deafness Disease variant Ligase Neurodegeneration Neuropathy Nucleotide-binding Phosphoprotein Protein biosynthesis Reference proteome Retinitis pigmentosa Usher syndrome | MAERAALEEL | MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLGDLKLLFEYLTLFGIDDKISF... | histidyl-tRNA aminoacylation mitochondrial translation translation tRNA aminoacylation for protein translation cytoplasm; cytosol; mitochondrion ATP binding histidine-tRNA ligase activity identical protein binding protein homodimerization activity RNA binding Homo sapiens 3D-structure Acetylation Alternative splicing A... |
fatty acid metabolic process fatty acid transport intestinal lipid absorption | apical cortex; cytosol; microvillus; nucleus | fatty acid binding long-chain fatty acid binding long-chain fatty acid transporter activity | Homo sapiens | 3D-structure Acetylation Cytoplasm Lipid-binding Reference proteome Transport | MAFDSTWKVD | MAFDSTWKVDRSENYDKFMEKMGVNIVKRKLAAHDNLKLTITQEGNKFTVKESSTFRNIEVVFELGVTFNYNLADGTELRGTWSLEGNKLIGKFKRTDNGNELNTVREIIGDELVQTYVYEGVEAKRIFKKD | fatty acid metabolic process fatty acid transport intestinal lipid absorption apical cortex; cytosol; microvillus; nucleus fatty acid binding long-chain fatty acid binding long-chain fatty acid transporter activity Homo sapiens 3D-structure Acetylation Cytoplasm Lipid-binding Reference proteome Transport MAFDSTWKVD MAF... |
extracellular matrix organization | collagen trimer; collagen-containing extracellular matrix; extracellular space | extracellular matrix structural constituent conferring tensile strength | Gallus gallus | Collagen Direct protein sequencing Disulfide bond Extracellular matrix Glycoprotein Hydroxylation Proteoglycan Reference proteome Repeat Secreted Signal | MAHRSPALCL | MAHRSPALCLLLLHAACLCLAQLRGPPGEPGPRGPPGPPGVPGADGIDGDKGSPGAPGSPGAKGEPGAPGPDGPPGKPGLDGLTGAKGSRGPWGGQGLKGQPGLPGPPGLPGPSLPGPPGLPGQVGLPGEIGVPGPKGDPGPDGPRGPPGPPGKPGPPGHIQGVEGSADFLCPTNCPPGPKGPQGLQGLKGHRGRPGALGEPGQQGKQGPKGDVGVSGEQGVPGPPGPQGQRGYPGMAGPKGETGPAGYKGMVGTIGAAGRPGREGPKGPPGDPGEKGELGGRGIRGPQGDIGPKGDMGLPGIDGKDGTPGIPGVKGTAG... | extracellular matrix organization collagen trimer; collagen-containing extracellular matrix; extracellular space extracellular matrix structural constituent conferring tensile strength Gallus gallus Collagen Direct protein sequencing Disulfide bond Extracellular matrix Glycoprotein Hydroxylation Proteoglycan Reference ... |
cell adhesion neuron apoptotic process phosphatidylinositol 3-kinase/protein kinase B signal transduction response to glucose response to UV | collagen trimer; collagen-containing extracellular matrix; endoplasmic reticulum lumen; extracellular exosome; extracellular region; extracellular space; extracellular vesicle; protein-containing complex; sarcolemma | collagen binding extracellular matrix structural constituent conferring tensile strength | Homo sapiens | Alternative splicing Cell adhesion Collagen Congenital muscular dystrophy Direct protein sequencing Disease variant Extracellular matrix Glycoprotein Hydroxylation Limb-girdle muscular dystrophy Membrane Phosphoprotein Reference proteome Repeat Secreted Signal | MLQGTCSVLL | MLQGTCSVLLLWGILGAIQAQQQEVISPDTTERNNNCPEKTDCPIHVYFVLDTSESVTMQSPTDILLFHMKQFVPQFISQLQNEFYLDQVALSWRYGGLHFSDQVEVFSPPGSDRASFIKNLQGISSFRRGTFTDCALANMTEQIRQDRSKGTVHFAVVITDGHVTGSPCGGIKLQAERAREEGIRLFAVAPNQNLKEQGLRDIASTPHELYRNDYATMLPDSTEIDQDTINRIIKVMKHEAYGECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKGA... | cell adhesion neuron apoptotic process phosphatidylinositol 3-kinase/protein kinase B signal transduction response to glucose response to UV collagen trimer; collagen-containing extracellular matrix; endoplasmic reticulum lumen; extracellular exosome; extracellular region; extracellular space; extracellular vesicle; pr... |
ADP biosynthetic process AMP metabolic process ATP metabolic process nucleoside triphosphate biosynthetic process phosphorylation | cytoplasm | adenylate kinase activity ATP binding nucleoside diphosphate kinase activity | Cyprinus carpio | Acetylation ATP-binding Cytoplasm Direct protein sequencing Kinase Nucleotide-binding Reference proteome Transferase | MADKIKDAKI | MADKIKDAKIVFVVGGPGSGKGTQCEKIVEKYGYTHLSSGDLLRAEVASGSERGKQLQAIMQKGELVPLDTVLDMIKDAMIAKADVSKGYLIDGYPREVKQGEEFEKKIGAPALLLYIDAKAETMVQRLMKRGQTSGRSDDNEETIKKRLDLYYKATEPVIAYYETRGIVRKINSELPVDEVFAIVVKAIDELK | ADP biosynthetic process AMP metabolic process ATP metabolic process nucleoside triphosphate biosynthetic process phosphorylation cytoplasm adenylate kinase activity ATP binding nucleoside diphosphate kinase activity Cyprinus carpio Acetylation ATP-binding Cytoplasm Direct protein sequencing Kinase Nucleotide-binding R... |
photosynthesis | chloroplast thylakoid membrane; photosystem I | 4 iron, 4 sulfur cluster binding chlorophyll binding electron transfer activity magnesium ion binding | Chlamydomonas reinhardtii | 3D-structure 4Fe-4S Chlorophyll Chloroplast Chromophore Electron transport Iron Iron-sulfur Magnesium Membrane Metal-binding Oxidoreductase Photosynthesis Photosystem I Plastid Reference proteome Thylakoid Transmembrane Transmembrane helix Transport | MTISTPEREA | MTISTPEREAKKVKIAVDRNPVETSFEKWAKPGHFSRTLSKGPNTTTWIWNLHADAHDFDSHTSDLEEISRKVFSAHFGQLGIIFIWLSGMYFHGARFSNYEAWLSDPTHIKPSAQVVWPIVGQEILNGDVGGGFQGIQITSGFFQLWRASGITSELQLYTTAIGGLVMAAAMFFAGWFHYHKAAPKLEWFQNVESMLNHHLGGLLGLGSLAWAGHQIHVSLPVNKLLDAGVDPKEIPLPHDLLLNRAIMADLYPSFAKGIAPFFTLNWSEYSDFLTFKGGLNPVTGGLWLSDTAHHHVAIAVLFLVAGHMYRTNWGIGH... | photosynthesis chloroplast thylakoid membrane; photosystem I 4 iron, 4 sulfur cluster binding chlorophyll binding electron transfer activity magnesium ion binding Chlamydomonas reinhardtii 3D-structure 4Fe-4S Chlorophyll Chloroplast Chromophore Electron transport Iron Iron-sulfur Magnesium Membrane Metal-binding Oxidor... |
angiogenesis cell differentiation in hindbrain fibroblast growth factor receptor signaling pathway mesoderm development nervous system development neural plate anterior/posterior regionalization positive regulation of angiogenesis positive regulation of blood vessel endothelial cell migration positive regulation of cel... | extracellular region; nucleus | growth factor activity heparin binding integrin binding | Xenopus laevis | Angiogenesis Developmental protein Differentiation Growth factor Heparin-binding Mitogen Nucleus Reference proteome Secreted | MAAGSITTLP | MAAGSITTLPTESEDGGNTPFSPGSFKDPKRLYCKNGGFFLRINSDGRVDGSRDKSDSHIKLQLQAVERGVVSIKGITANRYLAMKEDGRLTSLRCITDECFFFERLEANNYNTYRSRKYSSWYVALKRTGQYKNGSSTGPGQKAILFLPMSAKS | angiogenesis cell differentiation in hindbrain fibroblast growth factor receptor signaling pathway mesoderm development nervous system development neural plate anterior/posterior regionalization positive regulation of angiogenesis positive regulation of blood vessel endothelial cell migration positive regulation of cel... |
mitochondrial phosphate ion transmembrane transport phosphate ion transmembrane transport | mitochondrial inner membrane; mitochondrion | inorganic phosphate transmembrane transporter activity phosphate:proton symporter activity protein-containing complex binding symporter activity | Bos taurus | Acetylation Alternative splicing Direct protein sequencing Membrane Methylation Mitochondrion Mitochondrion inner membrane Phosphoprotein Reference proteome Repeat Symport Transit peptide Transmembrane Transmembrane helix Transport | MYSSVVHLAR | MYSSVVHLARANPFNAPHLQLVHDGLAGPRSDPAGPPGPPRRSRNLAAAAVEEQYSCDYGSGRFFILCGLGGIISCGTTHTALVPLDLVKCRMQVDPQKYKSIFNGFSVTLKEDGFRGLAKGWAPTFIGYSLQGLCKFGFYEVFKVLYSNMLGEENAYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASEVLKRLGFRGVWKGLFARII... | mitochondrial phosphate ion transmembrane transport phosphate ion transmembrane transport mitochondrial inner membrane; mitochondrion inorganic phosphate transmembrane transporter activity phosphate:proton symporter activity protein-containing complex binding symporter activity Bos taurus Acetylation Alternative splici... |
adaptive thermogenesis ADP transport apoptotic mitochondrial changes generation of precursor metabolites and energy mitochondrial ADP transmembrane transport mitochondrial ATP transmembrane transport mitochondrial genome maintenance negative regulation of mitochondrial outer membrane permeabilization involved in apopto... | membrane; mitochondrial inner membrane; mitochondrial membrane; mitochondrial permeability transition pore complex; mitochondrion; plasma membrane | adenine transmembrane transporter activity ATP:ADP antiporter activity oxidative phosphorylation uncoupler activity proton transmembrane transporter activity | Homo sapiens | Acetylation Antiport Cardiomyopathy Direct protein sequencing Disease variant Host-virus interaction Membrane Methylation Mitochondrion Mitochondrion inner membrane Phosphoprotein Primary mitochondrial disease Progressive external ophthalmoplegia Reference proteome Repeat S-nitrosylation Transmembrane Transmembrane hel... | MGDHAWSFLK | MGDHAWSFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRAAYFGVYDTAKGMLPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYV | adaptive thermogenesis ADP transport apoptotic mitochondrial changes generation of precursor metabolites and energy mitochondrial ADP transmembrane transport mitochondrial ATP transmembrane transport mitochondrial genome maintenance negative regulation of mitochondrial outer membrane permeabilization involved in apopto... |
apoptotic process mitochondrial ADP transmembrane transport mitochondrial ATP transmembrane transport negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | membrane; mitochondrial inner membrane; mitochondrion; nucleus; TIM23 mitochondrial import inner membrane translocase complex | ATP:ADP antiporter activity | Homo sapiens | Acetylation Antiport Apoptosis Direct protein sequencing Host-virus interaction Membrane Methylation Mitochondrion Mitochondrion inner membrane Reference proteome Repeat Transmembrane Transmembrane helix Transport | MTEQAISFAK | MTEQAISFAKDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVSVQGIIIYRAAYFGVYDTAKGMLPDPKNTHIVVSWMIAQTVTAVAGVVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIFRDEGGKAFFKGAWSNVLRGMGGAFVLVLYDELKKVI | apoptotic process mitochondrial ADP transmembrane transport mitochondrial ATP transmembrane transport negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway membrane; mitochondrial inner membrane; mitochondrion; nucleus; TIM23 mitochondrial import inner membrane tra... |
photosynthetic electron transport chain | photosystem II reaction center; plasma membrane-derived thylakoid membrane | electron transfer activity heme binding iron ion binding | Thermostichus vulcanus | 3D-structure Direct protein sequencing Electron transport Heme Iron Membrane Metal-binding Photosynthesis Photosystem II Thylakoid Transmembrane Transmembrane helix Transport | MAGTTGERPF | MAGTTGERPFSDIITSVRYWVIHSITIPALFIAGWLFVSTGLAYDVFGTPRPDSYYAQEQRSIPLVTDRFEAKQQVETFLEQLK | photosynthetic electron transport chain photosystem II reaction center; plasma membrane-derived thylakoid membrane electron transfer activity heme binding iron ion binding Thermostichus vulcanus 3D-structure Direct protein sequencing Electron transport Heme Iron Membrane Metal-binding Photosynthesis Photosystem II Thyl... |
photosynthetic electron transport chain | photosystem II reaction center; plasma membrane-derived thylakoid membrane | electron transfer activity heme binding iron ion binding | Thermostichus vulcanus | 3D-structure Direct protein sequencing Electron transport Heme Iron Membrane Metal-binding Photosynthesis Photosystem II Thylakoid Transmembrane Transmembrane helix Transport | MTSNTPNQEP | MTSNTPNQEPVSYPIFTVRWVAVHTLAVPTIFFLGAIAAMQFIQR | photosynthetic electron transport chain photosystem II reaction center; plasma membrane-derived thylakoid membrane electron transfer activity heme binding iron ion binding Thermostichus vulcanus 3D-structure Direct protein sequencing Electron transport Heme Iron Membrane Metal-binding Photosynthesis Photosystem II Thyl... |
adaptive thermogenesis brown fat cell differentiation cellular response to cold cellular response to dehydroepiandrosterone cellular response to fatty acid cellular response to hormone stimulus cellular response to reactive oxygen species diet induced thermogenesis mitochondrial transmembrane transport mitochondrial tr... | mitochondrial envelope; mitochondrial inner membrane; mitochondrion | cardiolipin binding GDP binding GTP binding long-chain fatty acid binding oxidative phosphorylation uncoupler activity proton transmembrane transporter activity purine ribonucleotide binding transmembrane transporter activity | Mus musculus | Ion channel Ion transport Membrane Mitochondrion Mitochondrion inner membrane Oxidation Reference proteome Repeat Selenium Selenocysteine Transmembrane Transmembrane helix Transport | MVNPTTSEVQ | MVNPTTSEVQPTMGVKIFSAGVSACLADIITFPLDTAKVRLQIQGEGQASSTIRYKGVLGTITTLAKTEGLPKLYSGLPAGIQRQISFASLRIGLYDSVQEYFSSGRETPASLGNKISAGLMTGGVAVFIGQPTEVVKVRMQAQSHLHGIKPRYTGTYNAYRVIATTESLSTLWKGTTPNLMRNVIINCTELVTYDLMKGALVNNKILADDVPCHLLSALVAGFCTTLLASPVDVVKTRFINSLPGQYPSVPSCAMSMYTKEGPTAFFKGFVASFLRLGSWNVIMFVCFEQLKKELMKSRQTVDCTT | adaptive thermogenesis brown fat cell differentiation cellular response to cold cellular response to dehydroepiandrosterone cellular response to fatty acid cellular response to hormone stimulus cellular response to reactive oxygen species diet induced thermogenesis mitochondrial transmembrane transport mitochondrial tr... |
innate immune response negative regulation by host of viral exo-alpha-sialidase activity negative regulation by host of viral glycoprotein metabolic process negative regulation of glycoprotein metabolic process negative regulation of monocyte differentiation negative regulation of viral entry into host cell negative re... | extracellular space; protein-containing complex | calcium ion binding carbohydrate binding complement component C1q complex binding identical protein binding virion binding | Mus musculus | Amyloid Calcium Disulfide bond Glycoprotein Lectin Metal-binding Reference proteome Secreted Signal | MDKLLLWMFV | MDKLLLWMFVFTSLLSEAFCQTDLKRKVFVFPRESETDHVKLIPHLEKPLQNFTLCFRTYSDLSRSQSLFSYSVKGRDNELLIYKEKVGEYSLYIGQSKVTVRGMEEYLSPVHLCTTWESSSGIVEFWVNGKPWVKKSLQREYTVKAPPSIVLGQEQDNYGGGFQRSQSFVGEFSDLYMWDYVLTPQDILFVYRDSPVNPNILNWQALNYEINGYVVIRPRVWD | innate immune response negative regulation by host of viral exo-alpha-sialidase activity negative regulation by host of viral glycoprotein metabolic process negative regulation of glycoprotein metabolic process negative regulation of monocyte differentiation negative regulation of viral entry into host cell negative re... |
carbohydrate metabolic process chondroitin sulfate catabolic process glucuronoside catabolic process heparan sulfate proteoglycan catabolic process hyaluronan catabolic process | endoplasmic reticulum; extracellular space; intracellular membrane-bounded organelle; lysosomal lumen; lysosome | beta-glucuronidase activity carbohydrate binding hydrolase activity protein domain specific binding signaling receptor binding | Mus musculus | Endoplasmic reticulum Glycoprotein Glycosidase Hydrolase Lysosome Reference proteome Signal | MSLKWSACWV | MSLKWSACWVALGQLLCSCALALKGGMLFPKESPSRELKALDGLWHFRADLSNNRLQGFEQQWYRQPLRESGPVLDMPVPSSFNDITQEAALRDFIGWVWYEREAILPRRWTQDTDMRVVLRINSAHYYAVVWVNGIHVVEHEGGHLPFEADISKLVQSGPLTTCRITIAINNTLTPHTLPPGTIVYKTDTSMYPKGYFVQDTSFDFFNYAGLHRSVVLYTTPTTYIDDITVITNVEQDIGLVTYWISVQGSEHFQLEVQLLDEGGKVVAHGTGNQGQLQVPSANLWWPYLMHEHPAYMYSLEVKVTTTESVTDYYTLPI... | carbohydrate metabolic process chondroitin sulfate catabolic process glucuronoside catabolic process heparan sulfate proteoglycan catabolic process hyaluronan catabolic process endoplasmic reticulum; extracellular space; intracellular membrane-bounded organelle; lysosomal lumen; lysosome beta-glucuronidase activity car... |
de novo' XMP biosynthetic process cellular response to interleukin-4 circadian rhythm GMP biosynthetic process GTP biosynthetic process lymphocyte proliferation | cytoplasm; cytosol; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; membrane; nucleus; peroxisomal membrane; secretory granule lumen | DNA binding IMP dehydrogenase activity metal ion binding nucleotide binding RNA binding | Homo sapiens | 3D-structure Acetylation CBS domain Cytoplasm Direct protein sequencing DNA-binding GMP biosynthesis Isopeptide bond Metal-binding NAD Nucleus Oxidoreductase Phosphoprotein Potassium Purine biosynthesis Reference proteome Repeat RNA-binding Ubl conjugation | MADYLISGGT | MADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDA... | de novo' XMP biosynthetic process cellular response to interleukin-4 circadian rhythm GMP biosynthetic process GTP biosynthetic process lymphocyte proliferation cytoplasm; cytosol; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; membrane; nucleus; peroxisomal membrane; secretory granule lumen... |
de novo' XMP biosynthetic process cellular response to interleukin-4 circadian rhythm GMP biosynthetic process GTP biosynthetic process lymphocyte proliferation | cytoplasm; cytosol; nucleus | IMP dehydrogenase activity metal ion binding nucleotide binding | Cricetulus griseus | 3D-structure Acetylation CBS domain Cytoplasm Direct protein sequencing GMP biosynthesis Isopeptide bond Metal-binding NAD Nucleus Oxidoreductase Phosphoprotein Potassium Purine biosynthesis Reference proteome Repeat Ubl conjugation | MADYLISGGT | MADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLPIVNENDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLALAGVDVVVLDSSQGNSIFQINMIKYMKEKYPNLQVIGGNVVTAAQAKNLIDAGVDA... | de novo' XMP biosynthetic process cellular response to interleukin-4 circadian rhythm GMP biosynthetic process GTP biosynthetic process lymphocyte proliferation cytoplasm; cytosol; nucleus IMP dehydrogenase activity metal ion binding nucleotide binding Cricetulus griseus 3D-structure Acetylation CBS domain Cytoplasm D... |
response to stimulus visual perception vitamin A metabolic process | cell body; centrosome; cytosol; nucleoplasm | 11-cis retinal binding phosphatidylinositol bisphosphate binding retinol binding | Homo sapiens | 3D-structure Acetylation Cytoplasm Disease variant Reference proteome Retinol-binding Sensory transduction Transport Vision | MSEGVGTFRM | MSEGVGTFRMVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHTLQKAKDELNEREETREEAVRELQEMVQAQAASGEELAVAVAERVQEKDSGFFLRFIRARKFNVGRAYELLRGYVNFRLQYPELFDSLSPEAVRCTIEAGYPGVLSSRDKYGRVVMLFNIENWQSQEITFDEILQAYCFILEKLLENEETQINGFCIIENFKGFTMQQAASLRTSDLRKMVDMLQDSFPARFKAIHFIHQPWYFTTTYNVVKPFLKSKLLERVFVHGDDLSGFYQEIDENILPSDFGGTLPKYDGKAVAEQLFGPQAQAENTAF | response to stimulus visual perception vitamin A metabolic process cell body; centrosome; cytosol; nucleoplasm 11-cis retinal binding phosphatidylinositol bisphosphate binding retinol binding Homo sapiens 3D-structure Acetylation Cytoplasm Disease variant Reference proteome Retinol-binding Sensory transduction Transpor... |
adenylate cyclase-activating G protein-coupled receptor signaling pathway bone mineralization cAMP metabolic process cell-cell signaling epidermis development female pregnancy negative regulation of cell population proliferation negative regulation of chondrocyte development negative regulation of chondrocyte different... | cytoplasm; cytosol; extracellular region; extracellular space; Golgi apparatus; nucleoplasm | hormone activity peptide hormone receptor binding | Homo sapiens | 3D-structure Alternative splicing Calcium Cleavage on pair of basic residues Cytoplasm Direct protein sequencing Disease variant Hormone Nucleus Reference proteome Secreted Signal | MQRRLVQQWS | MQRRLVQQWSVAVFLLSYAVPSCGRSVEGLSRRLKRAVSEHQLLHDKGKSIQDLRRRFFLHHLIAEIHTAEIRATSEVSPNSKPSPNTKNHPVRFGSDDEGRYLTQETNKVETYKEQPLKTPGKKKKGKPGKRKEQEKKKRRTRSAWLDSGVTGSGLEGDHLSDTSTTSLELDSRRH | adenylate cyclase-activating G protein-coupled receptor signaling pathway bone mineralization cAMP metabolic process cell-cell signaling epidermis development female pregnancy negative regulation of cell population proliferation negative regulation of chondrocyte development negative regulation of chondrocyte different... |
detection of chemical stimulus involved in sensory perception of bitter taste negative regulation of T cell apoptotic process positive regulation of gene expression proteolysis regulation of immune system process | extracellular exosome; extracellular region; extracellular space; nucleus | actin binding aspartic-type endopeptidase activity identical protein binding IgG binding | Homo sapiens | 3D-structure Actin-binding Direct protein sequencing Disulfide bond Glycoprotein Pyrrolidone carboxylic acid Reference proteome Secreted Signal | MRLLQLLFRA | MRLLQLLFRASPATLLLVLCLQLGANKAQDNTRKIIIKNFDIPKSVRPNDEVTAVLAVQTELKECMVVKTYLISSIPLQGAFNYKYTACLCDDNPKTFYWDFYTNRTVQIAAVVDVIRELGICPDDAAVIPIKNNRFYTIEILKVE | detection of chemical stimulus involved in sensory perception of bitter taste negative regulation of T cell apoptotic process positive regulation of gene expression proteolysis regulation of immune system process extracellular exosome; extracellular region; extracellular space; nucleus actin binding aspartic-type endop... |
futile creatine cycle phosphocreatine biosynthetic process phosphorylation substantia nigra development | cytosol; extracellular exosome; extracellular space; mitochondrion; plasma membrane | ATP binding creatine kinase activity ubiquitin protein ligase binding | Homo sapiens | 3D-structure ATP-binding Cell membrane Cytoplasm Direct protein sequencing Kinase Membrane Mitochondrion Nitration Nucleotide-binding Phosphoprotein Reference proteome Transferase | MPFSNSHNAL | MPFSNSHNALKLRFPAEDEFPDLSAHNNHMAKVLTPELYAELRAKSTPSGFTLDDVIQTGVDNPGHPYIMTVGCVAGDEESYEVFKDLFDPIIEDRHGGYKPSDEHKTDLNPDNLQGGDDLDPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKLAVEALSSLDGDLAGRYYALKSMTEAEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWVNEEDHLRVISMQKGGNMKEVFTRFCTGLTQIETLFKSKDYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKHEKFSEVLKRLRLQKR... | futile creatine cycle phosphocreatine biosynthetic process phosphorylation substantia nigra development cytosol; extracellular exosome; extracellular space; mitochondrion; plasma membrane ATP binding creatine kinase activity ubiquitin protein ligase binding Homo sapiens 3D-structure ATP-binding Cell membrane Cytoplasm ... |
Mo-molybdopterin cofactor biosynthetic process | cytoplasm; cytosol | identical protein binding metal ion binding molybdopterin molybdotransferase activity protein homodimerization activity | Escherichia coli | 3D-structure Magnesium Metal-binding Molybdenum Molybdenum cofactor biosynthesis Reference proteome Transferase | MEFTTGLMSL | MEFTTGLMSLDTALNEMLSRVTPLTAQETLPLVQCFGRILASDVVSPLDVPGFDNSAMDGYAVRLADIASGQPLPVAGKSFAGQPYHGEWPAGTCIRIMTGAPVPEGCEAVVMQEQTEQMDNGVRFTAEVRSGQNIRRRGEDISAGAVVFPAGTRLTTAELPVIASLGIAEVPVIRKVRVALFSTGDELQLPGQPLGDGQIYDTNRLAVHLMLEQLGCEVINLGIIRDDPHALRAAFIEADSQADVVISSGGVSVGEADYTKTILEELGEIAFWKLAIKPGKPFAFGKLSNSWFCGLPGNPVSATLTFYQLVQPLLAKLS... | Mo-molybdopterin cofactor biosynthetic process cytoplasm; cytosol identical protein binding metal ion binding molybdopterin molybdotransferase activity protein homodimerization activity Escherichia coli 3D-structure Magnesium Metal-binding Molybdenum Molybdenum cofactor biosynthesis Reference proteome Transferase MEFTT... |
Mo-molybdopterin cofactor biosynthetic process | cytoplasm; cytosol; molybdopterin cofactor (Moco) biosynthesis adenylyltransferase complex | ATP binding metal ion binding molybdopterin-synthase adenylyltransferase activity nucleotidyltransferase activity protein homodimerization activity sulfotransferase activity thiosulfate sulfurtransferase activity ubiquitin-like modifier activating enzyme activity | Escherichia coli | 3D-structure ATP-binding Metal-binding Molybdenum cofactor biosynthesis Nucleotide-binding Nucleotidyltransferase Reference proteome Transferase Zinc | MAELSDQEML | MAELSDQEMLRYNRQIILRGFDFDGQEALKDSRVLIVGLGGLGCAASQYLASAGVGNLTLLDFDTVSLSNLQRQTLHSDATVGQPKVESARDALTRINPHIAITPVNALLDDAELAALIAEHDLVLDCTDNVAVRNQLNAGCFAAKVPLVSGAAIRMEGQITVFTYQDGEPCYRCLSRLFGENALTCVEAGVMAPLIGVIGSLQAMEAIKMLAGYGKPASGKIVMYDAMTCQFREMKLMRNPGCEVCGQ | Mo-molybdopterin cofactor biosynthetic process cytoplasm; cytosol; molybdopterin cofactor (Moco) biosynthesis adenylyltransferase complex ATP binding metal ion binding molybdopterin-synthase adenylyltransferase activity nucleotidyltransferase activity protein homodimerization activity sulfotransferase activity thiosulf... |
methanol metabolic process | membrane; outer membrane-bounded periplasmic space | alcohol dehydrogenase (cytochrome c(L)) activity calcium ion binding | Paracoccus denitrificans | 3D-structure Calcium Direct protein sequencing Disulfide bond Metal-binding Methanol utilization Oxidoreductase Periplasm PQQ Signal | MNRNTPKARG | MNRNTPKARGASSLAMAVAMGLAVLTTAPATANDQLVELAKDPANWVMTGRDYNAQNYSEMTDINKENVKQLRPAWSFSTGVLHGHEGTPLVVGDRMFIHTPFPNTTFALDLNEPGKILWQNKPKQNPTARTVACCDVVNRGLAYWPGDDQVKPLIFRTQLDGHIVAMDAETGETRWIMENSDIKVGSTLTIAPYVIKDLVLVGSSGAELGVRGYVTAYDVKSGEMRWRAFATGPDEELLLAEDFNAPNPHYGQKNLGLETWEGDAWKIGGGTNWGWYAYDPEVDLFYYGSGNPAPWNETMRPGDNKWTMAIWGREATTG... | methanol metabolic process membrane; outer membrane-bounded periplasmic space alcohol dehydrogenase (cytochrome c(L)) activity calcium ion binding Paracoccus denitrificans3D-structure Calcium Direct protein sequencing Disulfide bond Metal-binding Methanol utilization Oxidoreductase Periplasm PQQ Signal MNRNTPKARG MNRNT... |
mitochondrial DNA metabolic process regulation of DNA recombination | endodeoxyribonuclease complex; mitochondrion | endonuclease activity | Saccharomyces cerevisiae | Direct protein sequencing Endonuclease Hydrolase Mitochondrion Nuclease | MKKQNLNSIL | MKKQNLNSILLMYINYIINYFNNIHKNQLKKDWIMEYEYMYKFLMNNMTCFIKWDNNKILLLLDMYYNVLYNYHKQRTPMSNKRLMNSKNIMDYKLLYTYFYILNKMKMEMDNYNNNNNNISLKYNELLKNIMNNLNYKTSNIETNLSNNFYLMDKYLINKYMKYLDMLNMIPNNYMFNNINYKGKLNIKTVLDLNNNEFYDYLSGLIEGDGYIGPGGITITNHANDVLNTIFINKRIKNSILVEKWMDTLKDNPYFVNAFSINIKTNLAKEKIFTNIYNKLYSDYKINQINNHIPYYNYLKINNKLPIKNIMDIKNNYW... | mitochondrial DNA metabolic process regulation of DNA recombination endodeoxyribonuclease complex; mitochondrion endonuclease activity Saccharomyces cerevisiae Direct protein sequencing Endonuclease Hydrolase Mitochondrion Nuclease MKKQNLNSIL MKKQNLNSILLMYINYIINYFNNIHKNQLKKDWIMEYEYMYKFLMNNMTCFIKWDNNKILLLLDMYYNVLYNYHKQR... |
base-excision repair, AP site formation via deaminated base removal | cytoplasm | uracil DNA N-glycosylase activity | Escherichia coli | 3D-structure Cytoplasm Direct protein sequencing DNA damage DNA repair Hydrolase Reference proteome | MANELTWHDV | MANELTWHDVLAEEKQQPYFLNTLQTVASERQSGVTIYPPQKDVFNAFRFTELGDVKVVILGQDPYHGPGQAHGLAFSVRPGIAIPPSLLNMYKELENTIPGFTRPNHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVVFLLWGSHAQKKGAIIDKQRHHVLKAPHPSPLSAHRGFFGCNHFVLANQWLEQRGETPIDWMPVLPAESE | base-excision repair, AP site formation via deaminated base removal cytoplasm uracil DNA N-glycosylase activity Escherichia coli 3D-structure Cytoplasm Direct protein sequencing DNA damage DNA repair Hydrolase Reference proteome MANELTWHDV MANELTWHDVLAEEKQQPYFLNTLQTVASERQSGVTIYPPQKDVFNAFRFTELGDVKVVILGQDPYHGPGQAHGLAFSVR... |
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