Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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cell population proliferation eye pigment biosynthetic process melanin biosynthetic process melanin biosynthetic process from tyrosine pigmentation response to blue light response to cAMP response to UV response to vitamin D thymus development visual perception | cytoplasm; Golgi-associated vesicle; intracellular membrane-bounded organelle; lysosome; melanosome; melanosome membrane; perinuclear region of cytoplasm | copper ion binding identical protein binding protein homodimerization activity tyrosinase activity | Homo sapiens | 3D-structure Albinism Alternative splicing Copper Deafness Disease variant Glycoprotein Melanin biosynthesis Membrane Metal-binding Monooxygenase Oxidoreductase Reference proteome Signal Transmembrane Transmembrane helix Tumor antigen Waardenburg syndrome | MLLAVLYCLL | MLLAVLYCLLWSFQTSAGHFPRACVSSKNLMEKECCPPWSGDRSPCGQLSGRGSCQNILLSNAPLGPQFPFTGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFWGPNCTERRLLVRRNIFDLSAPEKDKFFAYLTLAKHTISSDYVIPIGTYGQMKNGSTPMFNDINIYDLFVWMHYYVSMDALLGGSEIWRDIDFAHEAPAFLPWHRLFLLRWEQEIQKLTGDENFTIPYWDWRDAEKCDICTDEYMGGQHPTNPNLLSPASFFSSWQIVCSRLEEYNSHQSLCNGTPEGPLRRNPGNHDKSRTPRLPSSADVEF... | cell population proliferation eye pigment biosynthetic process melanin biosynthetic process melanin biosynthetic process from tyrosine pigmentation response to blue light response to cAMP response to UV response to vitamin D thymus development visual perception cytoplasm; Golgi-associated vesicle; intracellular membran... |
phosphorylation positive regulation of cell-substrate adhesion positive regulation of DNA-templated transcription positive regulation of response to extracellular stimulus protein kinase A signaling | cytoplasm; nucleus | ATP binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity | Saccharomyces cerevisiae | ATP-binding Cytoplasm Kinase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase Tyrosine-protein kinase | MNSSNNNDSS | MNSSNNNDSSSSNSNMNNSLSPTLVTHSDASMGSGRASPDNSHMGRGIWNPSYVNQGSQRSPQQQHQNHHQQQQQQQQQQQQNSQFCFVNPWNEEKVTNSQQNLVYPPQYDDLNSNESLDAYRRRKSSLVVPPARAPAPNPFQYDSYPAYTSSNTSLAGNSSGQYPSGYQQQQQQVYQQGAIHPSQFGSRFVPSLYDRQDFQRRQSLAATNYSSNFSSLNSNTNQGTNSIPVMSPYRRLSAYPPSTSPPLQPPFKQLRRDEVQGQKLSIPQMQLCNSKNDLQPVLNATPKFRRASLNSKTISPLVSVTKSLITTYSLCSP... | phosphorylation positive regulation of cell-substrate adhesion positive regulation of DNA-templated transcription positive regulation of response to extracellular stimulus protein kinase A signaling cytoplasm; nucleus ATP binding protein kinase activity protein serine kinase activity protein serine/threonine kinase act... |
cell cycle intracellular signal transduction invasive growth in response to glucose limitation pheromone-dependent signal transduction involved in conjugation with cellular fusion phosphorylation positive regulation of division septum assembly signal transduction involved in filamentous growth | cellular bud neck; cytoplasm; nucleus; periplasmic space | ATP binding MAP kinase activity protein kinase activity protein serine kinase activity protein serine/threonine kinase activity | Saccharomyces cerevisiae | ATP-binding Cell cycle Cytoplasm Kinase Nucleotide-binding Nucleus Periplasm Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MARTITFDIP | MARTITFDIPSQYKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKIQPFSKKLFVTRTIREIKLLRYFHEHENIISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTPSFEDFNQIKSKRAKEYIANLPMRPPLPWETVWSKTDLNPDMIDLLDKMLQFNPDKRISAAEALRHPYLAMYHDPS... | cell cycle intracellular signal transduction invasive growth in response to glucose limitation pheromone-dependent signal transduction involved in conjugation with cellular fusion phosphorylation positive regulation of division septum assembly signal transduction involved in filamentous growth cellular bud neck; cytopl... |
cell division cellular response to methylmercury DNA replication G1/S transition of mitotic cell cycle G2/M transition of mitotic cell cycle mitochondrial fusion mitotic intra-S DNA damage checkpoint signaling positive regulation of glucose transmembrane transport proteasome-mediated ubiquitin-dependent protein catabol... | chromosome, telomeric region; cytoplasm; nucleus; SCF ubiquitin ligase complex | ATP binding ubiquitin conjugating enzyme activity ubiquitin-protein transferase activity | Saccharomyces cerevisiae | 3D-structure ATP-binding Cell cycle Cell division Cytoplasm DNA replication Nucleotide-binding Nucleus Phosphoprotein Reference proteome Transferase Ubl conjugation pathway | MSSRKSTASS | MSSRKSTASSLLLRQYRELTDPKKAIPSFHIELEDDSNIFTWNIGVMVLNEDSIYHGGFFKAQMRFPEDFPFSPPQFRFTPAIYHPNVYRDGRLCISILHQSGDPMTDEPDAETWSPVQTVESVLISIVSLLEDPNINSPANVDAAVDYRKNPEQYKQRVKMEVERSKQDIPKGFIMPTSESAYISQSKLDEPESNKDMADNFWYDSDLDDDENGSVILQDDDYDDGNNHIPFEDDDVYNYNDNDDDDERIEFEDDDDDDDDSIDNDSVMDRKQPHKAEDESEDVEDVERVSKKI | cell division cellular response to methylmercury DNA replication G1/S transition of mitotic cell cycle G2/M transition of mitotic cell cycle mitochondrial fusion mitotic intra-S DNA damage checkpoint signaling positive regulation of glucose transmembrane transport proteasome-mediated ubiquitin-dependent protein catabol... |
cell differentiation immune complex clearance negative regulation of amyloid fibril formation positive regulation of apoptotic process positive regulation of receptor-mediated endocytosis protein stabilization regulation of cell population proliferation spermatogenesis | chromaffin granule; cytoplasm; cytosol; extracellular region; intracellular membrane-bounded organelle; mitochondrial inner membrane; mitochondrion; nucleus; perinuclear endoplasmic reticulum lumen | unfolded protein binding | Mesocricetus auratus | Chaperone Cytoplasm Cytoplasmic vesicle Developmental protein Differentiation Disulfide bond Endoplasmic reticulum Glycoprotein Membrane Microsome Mitochondrion Nucleus Phosphoprotein Reference proteome Secreted Spermatogenesis Ubl conjugation | NRRPHFLYPK | NRRPHFLYPKSRLIRSLLPPPHYGPLSFHDMFQPFLEMIHQAQQAMDVQFHSPAFQFPDMDLLREGEDDRAVCKEIRHNSTGCLKMKGQCEKCQEILSVDCSANNPAQAHLRQELNDSLQVAERLTQRYNELLHSLQTKMLNTSSLLEQLNEQFNWVSQLANLTQGEDQYYLRVSTVTTHSSDSEVPSRVT | cell differentiation immune complex clearance negative regulation of amyloid fibril formation positive regulation of apoptotic process positive regulation of receptor-mediated endocytosis protein stabilization regulation of cell population proliferation spermatogenesis chromaffin granule; cytoplasm; cytosol; extracellu... |
poly-hydroxybutyrate biosynthetic process | cytoplasm | acetoacetyl-CoA reductase activity | Cupriavidus necator | 3D-structure Cytoplasm NADP Oxidoreductase PHB biosynthesis Reference proteome | MTQRIAYVTG | MTQRIAYVTGGMGGIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQKALGFDFIASEGNVADWDSTKTAFDKVKSEVGEVDVLINNAGITRDVVFRKMTRADWDAVIDTNLTSLFNVTKQVIDGMADRGWGRIVNISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEVATKGVTVNTVSPGYIATDMVKAIRQDVLDKIVATIPVKRLGLPEEIASICAWLSSEESGFSTGADFSLNGGLHMG | poly-hydroxybutyrate biosynthetic process cytoplasm acetoacetyl-CoA reductase activity Cupriavidus necator 3D-structure Cytoplasm NADP Oxidoreductase PHB biosynthesis Reference proteome MTQRIAYVTG MTQRIAYVTGGMGGIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQKALGFDFIASEGNVADWDSTKTAFDKVKSEVGEVDVLINNAGITRDVVFRKMTRADWDAVIDTNLTSLFNVTKQ... |
inflammatory response interleukin-33-mediated signaling pathway macrophage differentiation negative regulation of cell population proliferation negative regulation of T-helper 1 type immune response negative regulation of type II interferon production positive regulation of chemokine production positive regulation of i... | cell surface; cytosol; external side of plasma membrane; extracellular space; focal adhesion; plasma membrane | interleukin-1 receptor activity interleukin-33 binding interleukin-33 receptor activity NAD(P)+ nucleosidase activity NAD+ nucleotidase, cyclic ADP-ribose generating | Mus musculus | 3D-structure Alternative splicing Cell membrane Disulfide bond Glycoprotein Hydrolase Immunoglobulin domain Isopeptide bond Membrane NAD Phosphoprotein Receptor Reference proteome Repeat Secreted Signal Transmembrane Transmembrane helix Ubl conjugation | MIDRQRMGLW | MIDRQRMGLWALAILTLPMYLTVTEGSKSSWGLENEALIVRCPQRGRSTYPVEWYYSDTNESIPTQKRNRIFVSRDRLKFLPARVEDSGIYACVIRSPNLNKTGYLNVTIHKKPPSCNIPDYLMYSTVRGSDKNFKITCPTIDLYNWTAPVQWFKNCKALQEPRFRAHRSYLFIDNVTHDDEGDYTCQFTHAENGTNYIVTATRSFTVEEKGFSMFPVITNPPYNHTMEVEIGKPASIACSACFGKGSHFLADVLWQINKTVVGNFGEARIQEEEGRNESSSNDMDCLTSVLRITGVTEKDLSLEYDCLALNLHGMIRHT... | inflammatory response interleukin-33-mediated signaling pathway macrophage differentiation negative regulation of cell population proliferation negative regulation of T-helper 1 type immune response negative regulation of type II interferon production positive regulation of chemokine production positive regulation of i... |
heterochromatin formation nuclear envelope organization nuclear migration nuclear pore localization protein localization to nuclear envelope | intermediate filament; nuclear envelope; nuclear lamina | structural constituent of cytoskeleton | Gallus gallus | Acetylation Coiled coil Intermediate filament Lipoprotein Methylation Nucleus Phosphoprotein Prenylation Reference proteome | MAAAVAPLSP | MAAAVAPLSPQPRGAAASAALSPTRISRLQEKEELRQLNDRLAVYIDKVRSLETENSALQRRVSEREQVCGREISGLKELFETELADARKTLDDTARERAKLQIELGKLRAEHEQVLSSYAKKDSDLNAAQVKLREFEAALNAKEAALATALGDKRSQEEELEDLRDQIAQLEVSLAAAKKELADETLQKVDLENRCQSLIEDLEFRKNVYEEEIKETRRKHETRLVEVDSGRQIEYEYKLAQALKEIREQHDAQVKLYKEELEQTYSSKLENIRQSSEMHSCTANTVREELHESRMRIETLSSHIADIQKESRAWQDRV... | heterochromatin formation nuclear envelope organization nuclear migration nuclear pore localization protein localization to nuclear envelope intermediate filament; nuclear envelope; nuclear lamina structural constituent of cytoskeleton Gallus gallus Acetylation Coiled coil Intermediate filament Lipoprotein Methylation ... |
heterochromatin formation nuclear envelope organization nuclear migration nuclear pore localization protein localization to nuclear envelope | intermediate filament; nuclear envelope; nuclear lamina | structural constituent of cytoskeleton | Gallus gallus | Acetylation Coiled coil Intermediate filament Lipoprotein Methylation Nucleus Phosphoprotein Prenylation Reference proteome | MSGTPIRGTP | MSGTPIRGTPGGTPLSPTRISRLQEKEELRQLNDRLAVYIDRVRALELENDRLLVKISEKEEVTTREVSGIKNLYESELADARRVLDETAKERARLQIEIGKLRAELEEFNKSYKKKDADLSVAQGRIKDLEVLFHRSEAELNTVLNEKRSLEAEVADLRAQLAKAEDGHAVAKKQLEKETLMRVDLENRCQSLQEDLDFRKNVFEEEIRETRKRHEHRLVEVDTSRQQEYENKMAQALEDLRNQHDEQVKLYKMELEQTYQAKLENAILASDQNDKAAGAAREELKEARMRIESLSHQLSGLQKQASATEDRIRELKET... | heterochromatin formation nuclear envelope organization nuclear migration nuclear pore localization protein localization to nuclear envelope intermediate filament; nuclear envelope; nuclear lamina structural constituent of cytoskeleton Gallus gallus Acetylation Coiled coil Intermediate filament Lipoprotein Methylation ... |
cellular response to L-glutamate heterochromatin formation nuclear envelope organization nuclear migration nuclear pore localization positive regulation of G2/M transition of mitotic cell cycle positive regulation of JNK cascade protein localization to nuclear envelope | lamin filament; nuclear envelope; nuclear inner membrane; nuclear lamina; nuclear matrix; nuclear membrane; nuclear periphery; nucleoplasm; nucleus | double-stranded DNA binding JUN kinase binding phospholipase binding sequence-specific double-stranded DNA binding structural constituent of cytoskeleton | Mus musculus | Acetylation Coiled coil Direct protein sequencing Disulfide bond Intermediate filament Isopeptide bond Lipoprotein Methylation Nucleus Phosphoprotein Prenylation Reference proteome Ubl conjugation | MATATPVQQQ | MATATPVQQQRAGSRASAPATPLSPTRLSRLQEKEELRELNDRLAVYIDKVRSLETENSALQLQVTEREEVRGRELTGLKALYETELADARRALDDTARERAKLQIELGKFKAEHDQLLLNYAKKESDLSGAQIKLREYEAALNSKDAALATALGDKKSLEGDLEDLKDQIAQLEASLSAAKKQLADETLLKVDLENRCQSLTEDLEFRKNMYEEEINETRRKHETRLVEVDSGRQIEYEYKLAQALHEMREQHDAQVRLYKEELEQTYHAKLENARLSSEMNTSTVNSAREELMESRMRIESLSSQLSNLQKESRACLE... | cellular response to L-glutamate heterochromatin formation nuclear envelope organization nuclear migration nuclear pore localization positive regulation of G2/M transition of mitotic cell cycle positive regulation of JNK cascade protein localization to nuclear envelope lamin filament; nuclear envelope; nuclear inner me... |
anatomical structure morphogenesis cell differentiation determination of adult lifespan DNA endoreduplication ecdysone-mediated induction of salivary gland cell autophagic cell death endoderm formation insulin receptor signaling pathway Malpighian tubule morphogenesis negative regulation of apoptotic process negative r... | nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific protein domain specific binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding | Drosophila melanogaster | Developmental protein DNA-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MQKLYAEPPP | MQKLYAEPPPSSAPVSMASSGGGGPPSGGGGGGGGGGGGGPPPPSNNNPNPTSNGGSMSPLARSAYTMNSMGLPVGGMSSVSPQAAATFSSSVLDSAAAVASMSASMSASMSASMNASMNGSMGAAAMNSMGGNCMTPSSMSYASMGSPLGNMGGCMAMSAASMSAAGLSGTYGAMPPGSREMETGSPNSLGRSRVDKPTTYRRSYTHAKPPYSYISLITMAIQNNPTRMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVKIPRTPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKDEKKEAIRQLHKS... | anatomical structure morphogenesis cell differentiation determination of adult lifespan DNA endoreduplication ecdysone-mediated induction of salivary gland cell autophagic cell death endoderm formation insulin receptor signaling pathway Malpighian tubule morphogenesis negative regulation of apoptotic process negative r... |
amyloid-beta clearance amyloid-beta clearance by cellular catabolic process amyloid-beta metabolic process antigen processing and presentation of endogenous peptide antigen via MHC class I bradykinin catabolic process hormone catabolic process insulin catabolic process insulin metabolic process insulin receptor signali... | basolateral plasma membrane; cell surface; cytoplasm; cytosol; external side of plasma membrane; extracellular exosome; extracellular space; mitochondrion; nucleus; peroxisomal matrix; peroxisome | ATP binding endopeptidase activity identical protein binding insulin binding metalloendopeptidase activity peptide binding protein homodimerization activity ubiquitin-dependent protein binding virus receptor activity zinc ion binding | Homo sapiens | 3D-structure Allosteric enzyme Alternative splicing ATP-binding Cell membrane Cytoplasm Direct protein sequencing Host cell receptor for virus entry Host-virus interaction Hydrolase Membrane Metal-binding Metalloprotease Nucleotide-binding Protease Receptor Reference proteome Secreted Zinc | MRYRLAWLLH | MRYRLAWLLHPALPSTFRSVLGARLPPPERLCGFQKKTYSKMNNPAIKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVCVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIP... | amyloid-beta clearance amyloid-beta clearance by cellular catabolic process amyloid-beta metabolic process antigen processing and presentation of endogenous peptide antigen via MHC class I bradykinin catabolic process hormone catabolic process insulin catabolic process insulin metabolic process insulin receptor signali... |
DNA topological change mismatch repair negative regulation of transcription by RNA polymerase II nucleotide-excision repair nucleotide-excision repair, DNA damage recognition proteasome-mediated ubiquitin-dependent protein catabolic process | cytoplasm; cytosol; nucleotide-excision repair factor 2 complex; nucleus; XPC complex | damaged DNA binding single-strand break-containing DNA binding single-stranded DNA binding | Saccharomyces cerevisiae | 3D-structure Cytoplasm DNA damage DNA repair DNA-binding Nucleus Reference proteome | MNEDLPKEYF | MNEDLPKEYFELIRKALNEKEAEKAPLSRRRRVRRKNQPLPDAKKKFKTGLNELPRESVVTVNLDSSDDGVVTVPTDDSVEEIQSSEEDYDSEEFEDVTDGNEVAGVEDISVEIKPSSKRNSDARRTSRNVCSNEERKRRKYFHMLYLVCLMVHGFIRNEWINSKRLSRKLSNLVPEKVFELLHPQKDEELPLRSTRKLLDGLKKCMELWQKHWKITKKYDNVGLYMRTWKEIEMSANNKRKFKTLKRSDFLRAVSKGHGDPDISVQGFVAMLRACNVNARLIMSCQPPDFTNMKIDTSLNGNNAYKDMVKYPIFWCEVW... | DNA topological change mismatch repair negative regulation of transcription by RNA polymerase II nucleotide-excision repair nucleotide-excision repair, DNA damage recognition proteasome-mediated ubiquitin-dependent protein catabolic process cytoplasm; cytosol; nucleotide-excision repair factor 2 complex; nucleus; XPC c... |
aggregation of unicellular organisms cell adhesion | extracellular region | fibrinogen binding fibronectin binding | Staphylococcus aureus | 3D-structure Cell adhesion Cell wall Peptidoglycan-anchor Reference proteome Repeat Secreted Signal Virulence | MKNNLRYGIR | MKNNLRYGIRKHKLGAASVFLGTMIVVGMGQDKEAAASEQKTTTVEENGNSATDNKTSETQTTATNVNHIEETQSYNATVTEQPSNATQVTTEEAPKAVQAPQTAQPANIETVKEEVVKEEAKPQVKETTQSQDNSGDQRQVDLTPKKATQNQVAETQVEVAQPRTASESKPRVTRSADVAEAKEASNAKVETGTDVTSKVTVEIGSIEGHNNTNKVEPHAGQRAVLKYKLKFENGLHQGDYFDFTLSNNVNTHGVSTARKVPEIKNGSVVMATGEVLEGGKIRYTFTNDIEDKVDVTAELEINLFIDPKTVQTNGNQTI... | aggregation of unicellular organisms cell adhesion extracellular region fibrinogen binding fibronectin binding Staphylococcus aureus 3D-structure Cell adhesion Cell wall Peptidoglycan-anchor Reference proteome Repeat Secreted Signal Virulence MKNNLRYGIR MKNNLRYGIRKHKLGAASVFLGTMIVVGMGQDKEAAASEQKTTTVEENGNSATDNKTSETQTTATN... |
B-1a B cell differentiation behavioral fear response cell adhesion endothelial cell migration locomotory exploration behavior negative regulation of extracellular matrix disassembly negative regulation of neutrophil chemotaxis positive regulation of cell population proliferation positive regulation of natural killer ce... | apical plasma membrane; cell surface; endocytic vesicle; extracellular region; intercellular canaliculus; lamellipodium; lamellipodium membrane; membrane raft; plasma membrane | aminopeptidase activity chemorepellent activity collagen binding dipeptidyl-peptidase activity identical protein binding peptide binding protease binding protein homodimerization activity serine-type endopeptidase activity serine-type peptidase activity signaling receptor binding virus receptor activity | Rattus norvegicus | 3D-structure Aminopeptidase Cell adhesion Cell junction Cell membrane Cell projection Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Membrane Protease Reference proteome Secreted Serine protease Signal-anchor Transmembrane Transmembrane helix | MKTPWKVLLG | MKTPWKVLLGLLGVAALVTIITVPVVLLNKDEAAADSRRTYTLADYLKNTFRVKSYSLRWVSDSEYLYKQENNILLFNAEHGNSSIFLENSTFEIFGDSISDYSVSPDRLFVLLEYNYVKQWRHSYTASYSIYDLNKRQLITEEKIPNNTQWITWSQEGHKLAYVWKNDIYVKIEPHLPSHRITSTGKENVIFNGINDWVYEEEIFGAYSALWWSPNGTFLAYAQFNDTGVPLIEYSFYSDESLQYPKTVWIPYPKAGAVNPTVKFFIVNTDSLSSTTTTIPMQITAPASVTTGDHYLCDVAWVSEDRISLQWLRRIQNY... | B-1a B cell differentiation behavioral fear response cell adhesion endothelial cell migration locomotory exploration behavior negative regulation of extracellular matrix disassembly negative regulation of neutrophil chemotaxis positive regulation of cell population proliferation positive regulation of natural killer ce... |
cytoplasmic translational initiation positive regulation of cellular response to amino acid starvation regulation of translational initiation translational initiation | cytosol; eukaryotic translation initiation factor 2B complex; guanyl-nucleotide exchange factor complex | enzyme regulator activity translation initiation factor activity | Saccharomyces cerevisiae | 3D-structure Acetylation Activator Cytoplasm Initiation factor Phosphoprotein Protein biosynthesis Reference proteome Repressor Translation regulation | MSEFNITETY | MSEFNITETYLRFLEEDTEMTMPIAAIEALVTLLRIKTPETAAEMINTIKSSTEELIKSIPNSVSLRAGCDIFMRFVLRNLHLYGDWENCKQHLIENGQLFVSRAKKSRNKIAEIGVDFIADDDIILVHGYSRAVFSLLNHAANKFIRFRCVVTESRPSKQGNQLYTLLEQKGIPVTLIVDSAVGAVIDKVDKVFVGAEGVAESGGIINLVGTYSVGVLAHNARKPFYVVTESHKFVRMFPLSSDDLPMAGPPLDFTRRTDDLEDALRGPTIDYTAQEYITALITDLGVLTPSAVSEELIKMWYD | cytoplasmic translational initiation positive regulation of cellular response to amino acid starvation regulation of translational initiation translational initiation cytosol; eukaryotic translation initiation factor 2B complex; guanyl-nucleotide exchange factor complex enzyme regulator activity translation initiation ... |
N-terminal peptidyl-glycine N-myristoylation | cytoplasm; cytosol | glycylpeptide N-tetradecanoyltransferase activity | Saccharomyces cerevisiae | 3D-structure Acyltransferase Cytoplasm Direct protein sequencing Reference proteome Transferase | MSEEDKAKKL | MSEEDKAKKLENLLKLLQLNNDDTSKFTQEQKKAMKDHKFWRTQPVKDFDEKVVEEGPIDKPKTPEDISDKPLPLLSSFEWCSIDVDNKKQLEDVFVLLNENYVEDRDAGFRFNYTKEFFNWALKSPGWKKDWHIGVRVKETQKLVAFISAIPVTLGVRGKQVPSVEINFLCVHKQLRSKRLTPVLIKEITRRVNKCDIWHALYTAGIVLPAPVSTCRYTHRPLNWKKLYEVDFTGLPDGHTEEDMIAENALPAKTKTAGLRKLKKEDIDQVFELFKRYQSRFELIQIFTKEEFEHNFIGEESLPLDKQVIFSYVVEQPD... | N-terminal peptidyl-glycine N-myristoylation cytoplasm; cytosol glycylpeptide N-tetradecanoyltransferase activity Saccharomyces cerevisiae 3D-structure Acyltransferase Cytoplasm Direct protein sequencing Reference proteome Transferase MSEEDKAKKL MSEEDKAKKLENLLKLLQLNNDDTSKFTQEQKKAMKDHKFWRTQPVKDFDEKVVEEGPIDKPKTPEDISDKPL... |
cell adhesion regulation of lamellipodium morphogenesis wound healing, spreading of cells | apical plasma membrane; cell projection; extracellular region; lamellipodium membrane; microvillus; plasma membrane | hyaluronic acid binding | Papio hamadryas | Cell adhesion Cell membrane Cell projection Direct protein sequencing Disulfide bond Glycoprotein Membrane Phosphoprotein Proteoglycan Receptor Secreted Signal Transmembrane Transmembrane helix | MDKFWWRAAW | MDKFWWRAAWGLCLVQLSLAQIDLNITCRFEGIYHVEKNGRYSISRTEAADLCKAFNSTLPTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFNASAPPGEDCTSVTDLPNAFDGPITITIVNRDGTRYVKKGEYRTNPEDINPSSPTDDDVSSGSSSERSSTLGGYIFYNHFSTSPPIPDEDGPWITDSTDRTPATRDQGAFDPSGGSHTTHGSESAGHSHGSREGGANTTSGPLRTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKKLVINNGNGAVEDRKSSGLN... | cell adhesion regulation of lamellipodium morphogenesis wound healing, spreading of cells apical plasma membrane; cell projection; extracellular region; lamellipodium membrane; microvillus; plasma membrane hyaluronic acid binding Papio hamadryas Cell adhesion Cell membrane Cell projection Direct protein sequencing Disu... |
calcineurin-mediated signaling cellular response to pheromone fungal-type cell wall organization intracellular monoatomic ion homeostasis positive regulation of DNA-templated transcription regulation of cell morphogenesis | calcineurin complex; cytoplasm | calmodulin binding calmodulin-dependent protein phosphatase activity metal ion binding myosin phosphatase activity | Saccharomyces cerevisiae | Calmodulin-binding Hydrolase Iron Metal-binding Phosphoprotein Protein phosphatase Reference proteome Zinc | MSSDAIRNTE | MSSDAIRNTEQINAAIKIIENKTERPQSSTTPIDSKASTVAAANSTATETSRDLTQYTLDDGRVVSTNRRIMNKVPAITSHVPTDEELFQPNGIPRHEFLRDHFKREGKLSAAQAARIVTLATELFSKEPNLISVPAPITVCGDIHGQYFDLLKLFEVGGDPATTSYLFLGDYVDRGSFSFECLIYLYSLKLNFNDHFWLLRGNHECKHLTSYFTFKNEMLHKYNLDIYEKCCESFNNLPLAALMNGQYLCVHGGISPELNSLQDINNLNRFREIPSHGLMCDLLWADPIEEYDEVLDKDLTEEDIVNSKTMVPHHGKMA... | calcineurin-mediated signaling cellular response to pheromone fungal-type cell wall organization intracellular monoatomic ion homeostasis positive regulation of DNA-templated transcription regulation of cell morphogenesis calcineurin complex; cytoplasm calmodulin binding calmodulin-dependent protein phosphatase activit... |
brain development cardiac muscle tissue morphogenesis cytokine-mediated signaling pathway decidualization heart development heart morphogenesis hemopoiesis negative regulation of neuron apoptotic process negative regulation of nitric oxide biosynthetic process positive regulation of cell population proliferation positi... | cell surface; external side of plasma membrane; extracellular region; nuclear speck; plasma membrane | erythropoietin receptor activity identical protein binding | Mus musculus | 3D-structure Alternative splicing Cell membrane Disulfide bond Glycoprotein Host-virus interaction Isopeptide bond Membrane Phosphoprotein Receptor Reference proteome Secreted Signal Transmembrane Transmembrane helix Ubl conjugation | MDKLRVPLWP | MDKLRVPLWPRVGPLCLLLAGAAWAPSPSLPDPKFESKAALLASRGSEELLCFTQRLEDLVCFWEEAASSGMDFNYSFSYQLEGESRKSCSLHQAPTVRGSVRFWCSLPTADTSSFVPLELQVTEASGSPRYHRIIHINEVVLLDAPAGLLARRAEEGSHVVLRWLPPPGAPMTTHIRYEVDVSAGNRAGGTQRVEVLEGRTECVLSNLRGGTRYTFAVRARMAEPSFSGFWSAWSEPASLLTASDLDPLILTLSLILVLISLLLTVLALLSHRRTLQQKIWPGIPSPESEFEGLFTTHKGNFQLWLLQRDGCLWWSPGS... | brain development cardiac muscle tissue morphogenesis cytokine-mediated signaling pathway decidualization heart development heart morphogenesis hemopoiesis negative regulation of neuron apoptotic process negative regulation of nitric oxide biosynthetic process positive regulation of cell population proliferation positi... |
fatty acid metabolic process | cytosol | L-gulonate 3-dehydrogenase activity NAD+ binding protein homodimerization activity structural constituent of eye lens | Oryctolagus cuniculus | 3D-structure Acetylation Cytoplasm Direct protein sequencing Eye lens protein NAD Oxidoreductase Phosphoprotein Reference proteome | MASPAAGDVL | MASPAAGDVLIVGSGLVGRSWAMLFASGGFRVKLYDIEPRQITGALENIRKEMKSLQQSGSLKGSLSAEEQLSLISSCTNLAEAVEGVVHIQECVPENLDLKRKIFAQLDSIVDDRVVLSSSSSCLLPSKLFTGLAHVKQCIVAHPVNPPYYIPLVELVPHPETSPATVDRTHALMRKIGQSPVRVLKEIDGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSDGLGMRYAFIGPLETMHLNAEGMLSYCDRYSEGMKRVLKSFGSIPEFSGATVEKVNQAMCKKVPADPEHLAARREWRDECLKRLAKLKRQMQPQ | fatty acid metabolic process cytosol L-gulonate 3-dehydrogenase activity NAD+ binding protein homodimerization activity structural constituent of eye lens Oryctolagus cuniculus 3D-structure Acetylation Cytoplasm Direct protein sequencing Eye lens protein NAD Oxidoreductase Phosphoprotein Reference proteome MASPAAGDVL M... |
bacterial-type flagellum-dependent swarming motility protein secretion by the type II secretion system protein transport by the Sec complex proteolysis single-species biofilm formation | extracellular region | endopeptidase activity metal ion binding metalloendopeptidase activity | Pseudomonas aeruginosa | 3D-structure Autocatalytic cleavage Calcium Direct protein sequencing Disulfide bond Hydrolase Metal-binding Metalloprotease Protease Reference proteome Secreted Signal Virulence Zinc Zymogen | MKKVSTLDLL | MKKVSTLDLLFVAIMGVSPAAFAADLIDVSKLPSKAAQGAPGPVTLQAAVGAGGADELKAIRSTTLPNGKQVTRYEQFHNGVRVVGEAITEVKGPGKSVAAQRSGHFVANIAADLPGSTTAAVSAEQVLAQAKSLKAQGRKTENDKVELVIRLGENNIAQLVYNVSYLIPGEGLSRPHFVIDAKTGEVLDQWEGLAHAEAGGPGGNQKIGKYTYGSDYGPLIVNDRCEMDDGNVITVDMNSSTDDSKTTPFRFACPTNTYKQVNGAYSPLNDAHFFGGVVFKLYRDWFGTSPLTHKLYMKVHYGRSVENAYWDGTAMLFG... | bacterial-type flagellum-dependent swarming motility protein secretion by the type II secretion system protein transport by the Sec complex proteolysis single-species biofilm formation extracellular region endopeptidase activity metal ion binding metalloendopeptidase activity Pseudomonas aeruginosa 3D-structure Autocat... |
carbohydrate metabolic process lipid glycosylation protein glycosylation | Golgi apparatus; Golgi cisterna; Golgi cisterna membrane; vesicle | glycosyltransferase activity metal ion binding N-acetyllactosaminide 3-alpha-galactosyltransferase activity | Bos taurus | 3D-structure Glycoprotein Glycosyltransferase Golgi apparatus Manganese Membrane Metal-binding Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix | MNVKGKVILS | MNVKGKVILSMLVVSTVIVVFWEYIHSPEGSLFWINPSRNPEVGGSSIQKGWWLPRWFNNGYHEEDGDINEEKEQRNEDESKLKLSDWFNPFKRPEVVTMTKWKAPVVWEGTYNRAVLDNYYAKQKITVGLTVFAVGRYIEHYLEEFLTSANKHFMVGHPVIFYIMVDDVSRMPLIELGPLRSFKVFKIKPEKRWQDISMMRMKTIGEHIVAHIQHEVDFLFCMDVDQVFQDKFGVETLGESVAQLQAWWYKADPNDFTYERRKESAAYIPFGEGDFYYHAAIFGGTPTQVLNITQECFKGILKDKKNDIEAQWHDESHL... | carbohydrate metabolic process lipid glycosylation protein glycosylation Golgi apparatus; Golgi cisterna; Golgi cisterna membrane; vesicle glycosyltransferase activity metal ion binding N-acetyllactosaminide 3-alpha-galactosyltransferase activity Bos taurus 3D-structure Glycoprotein Glycosyltransferase Golgi apparatus ... |
coenzyme A metabolic process ecdysis, chitin-based cuticle embryonic heart tube development germ cell attraction germ cell migration gonad development isoprenoid biosynthetic process locomotory behavior pole cell migration positive regulation of Ras protein signal transduction sterol biosynthetic process | endoplasmic reticulum membrane; peroxisomal membrane | hydroxymethylglutaryl-CoA reductase (NADPH) activity NADP binding | Drosophila melanogaster | Endoplasmic reticulum Glycoprotein Isoprene biosynthesis Membrane NADP Oxidoreductase Reference proteome Transmembrane Transmembrane helix | MIGRLFRAHG | MIGRLFRAHGEFCASHPWEVIVALLTITACMLTVDKNNTLDASSGLGTATASAAAAGGSGSGAGSGASGTIPPSSMGGSATSSRHRPCHGWSQSCDGLEAEYNAADVILMTIVRCTAVLYCYYQFCSLHRLGSKYVLGIAGLFTVFSSFIFTTAIIKFLGSDISELKDALFFLLLVIDLSNSGRLAQLALSGSNQAEVTQNIARGLELLGPAISLDTIVEVLLVGVGTLSGVQRLEVLCMFAVLSVLVNYVVFMTFYPACLSLIFDLSRSGVDMSVVREKAKGSLLLKSLTEEEQKANPVLQRVKLIMTTGLMAVHIYSR... | coenzyme A metabolic process ecdysis, chitin-based cuticle embryonic heart tube development germ cell attraction germ cell migration gonad development isoprenoid biosynthetic process locomotory behavior pole cell migration positive regulation of Ras protein signal transduction sterol biosynthetic process endoplasmic re... |
cell surface receptor signaling pathway immune response inflammatory response interleukin-1-mediated signaling pathway positive regulation of interleukin-1-mediated signaling pathway positive regulation of neutrophil extravasation positive regulation of T-helper 1 cell cytokine production positive regulation of type II... | external side of plasma membrane; extracellular region; membrane; plasma membrane | interleukin-1 binding interleukin-1 receptor activity interleukin-1, type I, activating receptor activity NAD(P)+ nucleosidase activity NAD+ nucleotidase, cyclic ADP-ribose generating platelet-derived growth factor receptor binding protease binding transmembrane signaling receptor activity | Homo sapiens | 3D-structure Cell membrane Disulfide bond Glycoprotein Hydrolase Immunoglobulin domain Inflammatory response Membrane NAD Phosphoprotein Receptor Reference proteome Repeat Secreted Signal Transmembrane Transmembrane helix | MKVLLRLICF | MKVLLRLICFIALLISSLEADKCKEREEKIILVSSANEIDVRPCPLNPNEHKGTITWYKDDSKTPVSTEQASRIHQHKEKLWFVPAKVEDSGHYYCVVRNSSYCLRIKISAKFVENEPNLCYNAQAIFKQKLPVAGDGGLVCPYMEFFKNENNELPKLQWYKDCKPLLLDNIHFSGVKDRLIVMNVAEKHRGNYTCHASYTYLGKQYPITRVIEFITLEENKPTRPVIVSPANETMEVDLGSQIQLICNVTGQLSDIAYWKWNGSVIDEDDPVLGEDYYSVENPANKRRSTLITVLNISEIESRFYKHPFTCFAKNTHGI... | cell surface receptor signaling pathway immune response inflammatory response interleukin-1-mediated signaling pathway positive regulation of interleukin-1-mediated signaling pathway positive regulation of neutrophil extravasation positive regulation of T-helper 1 cell cytokine production positive regulation of type II... |
cytokine-mediated signaling pathway immunoglobulin mediated immune response interleukin-15-mediated signaling pathway interleukin-2-mediated signaling pathway negative regulation of apoptotic process positive regulation of phagocytosis protein-containing complex assembly signal transduction | cell surface; cytosol; endosome; external side of plasma membrane; interleukin-2 receptor complex; membrane; plasma membrane | coreceptor activity cytokine receptor activity interleukin-15 receptor activity interleukin-2 binding interleukin-2 receptor activity | Homo sapiens | 3D-structure Cell membrane Disease variant Disulfide bond Glycoprotein Host-virus interaction Membrane Receptor Reference proteome Signal Transmembrane Transmembrane helix | MAAPALSWRL | MAAPALSWRLPLLILLLPLATSWASAAVNGTSQFTCFYNSRANISCVWSQDGALQDTSCQVHAWPDRRRWNQTCELLPVSQASWACNLILGAPDSQKLTTVDIVTLRVLCREGVRWRVMAIQDFKPFENLRLMAPISLQVVHVETHRCNISWEISQASHYFERHLEFEARTLSPGHTWEEAPLLTLKQKQEWICLETLTPDTQYEFQVRVKPLQGEFTTWSPWSQPLAFRTKPAALGKDTIPWLGHLLVGLSGAFGFIILVYLLINCRNTGPWLKKVLKCNTPDPSKFFSQLSSEHGGDVQKWLSSPFPSSSFSPGGLAP... | cytokine-mediated signaling pathway immunoglobulin mediated immune response interleukin-15-mediated signaling pathway interleukin-2-mediated signaling pathway negative regulation of apoptotic process positive regulation of phagocytosis protein-containing complex assembly signal transduction cell surface; cytosol; endos... |
asymmetric neuroblast division mitotic cell cycle mitotic cell cycle phase transition mitotic sister chromatid segregation positive regulation of stem cell differentiation regulation of chromatin binding regulation of exit from mitosis regulation of mitotic cell cycle, embryonic regulation of mitotic nuclear division s... | cyclin A2-CDK2 complex; cytoplasm; cytosol; fusome; male germ cell nucleus; nucleus; spectrosome; synapse | cyclin-dependent protein serine/threonine kinase regulator activity | Drosophila melanogaster | Alternative splicing Cell cycle Cell division Cyclin Mitosis Reference proteome | MASFQIHQDM | MASFQIHQDMSNKENPGIKIPAGVKNTKQPLAVIGGKAEKNALAPRANFAVLNGNNNVPRPAGKVQVFRDVRNLNVDENVEYGAKKSNVVPVVEQFKTFSVYEDNNDTQVAPSGKSLASLVDKENHDVKFGAGQKELVDYDLDSTPMSVTDVQSPMSVDRSILGVIQSSDISVGTETGVSPTGRVKELPPRNDRQRFLEVVQYQMDILEYFRESEKKHRPKPLYMRRQKDISHNMRSILIDWLVEVSEEYKLDTETLYLSVFYLDRFLSQMAVVRSKLQLVGTAAMYIAAKYEEIYPPEVGEFVFLTDDSYTKAQVLRME... | asymmetric neuroblast division mitotic cell cycle mitotic cell cycle phase transition mitotic sister chromatid segregation positive regulation of stem cell differentiation regulation of chromatin binding regulation of exit from mitosis regulation of mitotic cell cycle, embryonic regulation of mitotic nuclear division s... |
peptidoglycan catabolic process protein secretion by the type II secretion system protein transport by the Sec complex proteolysis septum digestion after cytokinesis | extracellular space | endopeptidase activity metal ion binding metalloendopeptidase activity | Pseudomonas aeruginosa | 3D-structure Direct protein sequencing Disulfide bond Hydrolase Metal-binding Metalloprotease Protease Reference proteome Secreted Signal Virulence Zinc Zymogen | MQHKRSRAMA | MQHKRSRAMASPRSPFLFVLLALAVGGTANAHDDGLPAFRYSAELLGQLQLPSVALPLNDDLFLYGRDAEAFDLEAYLALNAPALRDKSEYLEHWSGYYSINPKVLLTLMVMQSGPLGAPDERALAAPLGRLSAKRGFDAQVRDVLQQLSRRYYGFEEYQLRQAAARKAVGEDGLNAASAALLGLLREGAKVSAVQGGNPLGAYAQTFQRLFGTPAAELLQPSNRVARQLQAKAALAPPSNLMQLPWRQGYSWQPNGAHSNTGSGYPYSSFDASYDWPRWGSATYSVVAAHAGTVRVLSRCQVRVTHPSGWATNYYHMDQ... | peptidoglycan catabolic process protein secretion by the type II secretion system protein transport by the Sec complex proteolysis septum digestion after cytokinesis extracellular space endopeptidase activity metal ion binding metalloendopeptidase activity Pseudomonas aeruginosa 3D-structure Direct protein sequencing D... |
heme catabolic process heme oxidation response to oxidative stress | endoplasmic reticulum membrane | heme binding heme oxygenase (decyclizing) activity metal ion binding | Gallus gallus | Direct protein sequencing Endoplasmic reticulum Heme Iron Membrane Metal-binding Oxidoreductase Reference proteome Transmembrane Transmembrane helix | METSQPHNAE | METSQPHNAESMSQDLSELLKEATKEVHEQAENTPFMKNFQKGQVSLHEFKLVTASLYFIYSALEEEIERNKDNPVYAPVYFPMELHRKAALEKDLEYFYGSNWRAEIPCPEATQKYVERLHVVGKKHPELLVAHAYTRYLGDLSGGQVLKKIAQKALQLPSTGEGLAFFTFDGVSNATKFKQLYRSRMNALEMDHATKKRVLEEAKKAFLLNIQVFEALQKLVSKSQENGHAVQPKAELRTRSVNKSHENSPAAGKESERTSRMQADMLTTSPLVRWLLALGFIATTVAVGLFAM | heme catabolic process heme oxidation response to oxidative stress endoplasmic reticulum membrane heme binding heme oxygenase (decyclizing) activity metal ion binding Gallus gallus Direct protein sequencing Endoplasmic reticulum Heme Iron Membrane Metal-binding Oxidoreductase Reference proteome Transmembrane Transmembr... |
apoptotic signaling pathway calcium ion transport growth plate cartilage chondrocyte differentiation mitochondrial calcium ion homeostasis monoatomic ion transmembrane transport negative regulation of sequestering of calcium ion neural crest cell migration plasma membrane repair regulation of muscle contraction | apical plasma membrane; collagen-containing extracellular matrix; cytoplasm; cytosol; focal adhesion; intercalated disc; late endosome membrane; lysosomal membrane; melanosome; membrane; mitochondrion; perinuclear region of cytoplasm; protein-containing complex; sarcolemma | actin filament binding calcium channel activity calcium ion binding calcium-dependent phospholipid binding calcium-dependent protein binding cholesterol binding chondroitin sulfate binding GTP binding identical protein binding ligand-gated monoatomic ion channel activity lipid binding phosphatidylserine binding protein... | Mus musculus | Acetylation Annexin Calcium Calcium/phospholipid-binding Cytoplasm Direct protein sequencing Phosphoprotein Reference proteome Repeat | MAKIAQGAMY | MAKIAQGAMYRGSVHDFPEFDANQDAEALYTAMKGFGSDKESILELITSRSNKQRQEICQNYKSLYGKDLIEDLKYELTGKFERLIVNLMRPLAYCDAKEIKDAISGVGTDEKCLIEILASRTNEQMHQLVAAYKDAYERDLESDIIGDTSGHFQKMLVVLLQGTRENDDVVSEDLVQQDVQDLYEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRSTPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSGEYKKALLKL... | apoptotic signaling pathway calcium ion transport growth plate cartilage chondrocyte differentiation mitochondrial calcium ion homeostasis monoatomic ion transmembrane transport negative regulation of sequestering of calcium ion neural crest cell migration plasma membrane repair regulation of muscle contraction apical ... |
ascospore formation cellular response to starvation DNA damage response negative regulation of meiotic nuclear division positive regulation of meiotic nuclear division protein folding protein metabolic process protein transport | cytoplasm; mitochondrial intermembrane space; mitochondrion; nucleus; Set3 complex | cyclosporin A binding mRNA binding peptidyl-prolyl cis-trans isomerase activity | Saccharomyces cerevisiae | 3D-structure Acetylation Cytoplasm Direct protein sequencing Isomerase Isopeptide bond Mitochondrion Nucleus Phosphoprotein Protein transport Reference proteome Rotamase Transport Ubl conjugation | MSQVYFDVEA | MSQVYFDVEADGQPIGRVVFKLYNDIVPKTAENFRALCTGEKGFGYAGSPFHRVIPDFMLQGGDFTAGNGTGGKSIYGGKFPDENFKKHHDRPGLLSMANAGPNTNGSQFFITTVPCPWLDGKHVVFGEVVDGYDIVKKVESLGSPSGATKARIVVAKSGEL | ascospore formation cellular response to starvation DNA damage response negative regulation of meiotic nuclear division positive regulation of meiotic nuclear division protein folding protein metabolic process protein transport cytoplasm; mitochondrial intermembrane space; mitochondrion; nucleus; Set3 complex cyclospor... |
photosynthesis protein stabilization | plasma membrane-derived thylakoid membrane; plasma membrane-derived thylakoid photosystem II | phosphate ion binding | Synechocystis sp. | 3D-structure Direct protein sequencing Membrane Photosynthesis Photosystem II Reference proteome Thylakoid Transmembrane Transmembrane helix | MAQRTRLGDI | MAQRTRLGDILRPLNSEYGKVVPGWGTTPVMGVFMALFLVFLLIILQIYNSSLILEGFSVDWAG | photosynthesis protein stabilization plasma membrane-derived thylakoid membrane; plasma membrane-derived thylakoid photosystem II phosphate ion binding Synechocystis sp. 3D-structure Direct protein sequencing Membrane Photosynthesis Photosystem II Reference proteome Thylakoid Transmembrane Transmembrane helix MAQRTRLGD... |
cellular response to hydrogen peroxide cellular response to oxidative stress defense response embryo implantation eye development male gonad development negative regulation of blood vessel remodeling negative regulation of collagen catabolic process negative regulation of elastin catabolic process negative regulation o... | axon; basement membrane; cell projection; contractile fiber; cytoplasm; extracellular region; extracellular space; Golgi apparatus; multivesicular body; neuronal cell body; nuclear membrane; perinuclear region of cytoplasm; plasma membrane; vesicle | amyloid-beta binding cysteine-type endopeptidase inhibitor activity endopeptidase inhibitor activity identical protein binding peptidase inhibitor activity protease binding | Rattus norvegicus | Direct protein sequencing Disulfide bond Glycoprotein Protease inhibitor Reference proteome Secreted Signal Thiol protease inhibitor | MASPLRSLML | MASPLRSLMLLLAVLAVAWAGTSRPPPRLLGAPQEADASEEGVQRALDFAVSEYNKGSNDAYHSRAIQVVRARKQLVAGINYYLDVEMGRTTCTKSQTNLTNCPFHDQPHLMRKALCSFQIYSVPWKGTHTLTKSSCKNA | cellular response to hydrogen peroxide cellular response to oxidative stress defense response embryo implantation eye development male gonad development negative regulation of blood vessel remodeling negative regulation of collagen catabolic process negative regulation of elastin catabolic process negative regulation o... |
acute-phase response cellular response to calcium ion complement activation, classical pathway innate immune response negative regulation of lipid storage negative regulation of macrophage derived foam cell differentiation negative regulation of mononuclear cell proliferation negative regulation of superoxide anion gen... | extracellular space; filopodium; growth cone | calcium ion binding cholesterol binding complement component C1q complex binding identical protein binding low-density lipoprotein particle binding low-density lipoprotein particle receptor binding | Mus musculus | Acute phase Calcium Disulfide bond Metal-binding Reference proteome Secreted Signal | MEKLLWCLLI | MEKLLWCLLIMISFSRTFGHEDMFKKAFVFPKESDTSYVSLEAESKKPLNTFTVCLHFYTALSTVRSFSVFSYATKKNSNDILIFWNKDKQYTFGVGGAEVRFMVSEIPEAPTHICASWESATGIVEFWIDGKPKVRKSLHKGYTVGPDASIILGQEQDSYGGDFDAKQSLVGDIGDVNMWDFVLSPEQISTVYVGGTLSPNVLNWRALNYKAQGDVFIKPQLWS | acute-phase response cellular response to calcium ion complement activation, classical pathway innate immune response negative regulation of lipid storage negative regulation of macrophage derived foam cell differentiation negative regulation of mononuclear cell proliferation negative regulation of superoxide anion gen... |
activation of protein kinase B activity apoptotic process cell adhesion molecule production cellular response to oxidative stress endothelial cell activation leukocyte chemotaxis negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway negative regulation of protein K48-linked ubiquitinatio... | cytoplasm; cytosol; extracellular region; midbody; nucleus | cyclosporin A binding heparan sulfate binding integrin binding peptidyl-prolyl cis-trans isomerase activity | Cricetulus griseus | Acetylation Apoptosis Cytoplasm Glycoprotein Isomerase Isopeptide bond Nucleus Phosphoprotein Rotamase Secreted Ubl conjugation | MVNPTVFFDI | MVNPTVFFDISADGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSSFHRIIPGFMCQGGDFTRHNGTGGRSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITISDCGQL | activation of protein kinase B activity apoptotic process cell adhesion molecule production cellular response to oxidative stress endothelial cell activation leukocyte chemotaxis negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway negative regulation of protein K48-linked ubiquitinatio... |
cellular respiration mitochondrial electron transport, cytochrome c to oxygen substantia nigra development | mitochondrial inner membrane; mitochondrial membrane; mitochondrial respiratory chain complex IV; mitochondrion; respiratory chain complex IV | cytochrome-c oxidase activity | Homo sapiens | 3D-structure Acetylation Disease variant Disulfide bond Membrane Mitochondrion Mitochondrion inner membrane Primary mitochondrial disease Reference proteome | MAEDMETKIK | MAEDMETKIKNYKTAPFDSRFPNQNQTRNCWQNYLDFHRCQKAMTAKGGDISVCEWYQRVYQSLCPTSWVTDWDEQRAEGTFPGKI | cellular respiration mitochondrial electron transport, cytochrome c to oxygen substantia nigra development mitochondrial inner membrane; mitochondrial membrane; mitochondrial respiratory chain complex IV; mitochondrion; respiratory chain complex IV cytochrome-c oxidase activity Homo sapiens 3D-structure Acetylation Dis... |
negative regulation of DNA-templated transcription positive regulation of miRNA transcription positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II | chromatin; endoplasmic reticulum; intracellular membrane-bounded organelle; nucleoplasm; nucleus; RNA polymerase II transcription regulator complex | DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific identical protein binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding sequenc... | Homo sapiens | 3D-structure Activator Alternative splicing DNA-binding Homeobox Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MNNPSETSKP | MNNPSETSKPSMESGDGNTGTQTNGLDFQKQPVPVGGAISTAQAQAFLGHLHQVQLAGTSLQAAAQSLNVQSKSNEESGDSQQPSQPSQQPSVQAAIPQTQLMLAGGQITGLTLTPAQQQLLLQQAQAQAQLLAAAVQQHSASQQHSAAGATISASAATPMTQIPLSQPIQIAQDLQQLQQLQQQNLNLQQFVLVHPTTNLQPAQFIISQTPQGQQGLLQAQNLLTQLPQQSQANLLQSQPSITLTSQPATPTRTIAATPIQTLPQSQSTPKRIDTPSLEEPSDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGND... | negative regulation of DNA-templated transcription positive regulation of miRNA transcription positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II chromatin; endoplasmic reticulum; intracellular membrane-bounded organelle; nucleoplasm; nucleus; RNA polymerase II tra... |
mRNA processing negative regulation of DNA-templated transcription regulation of alternative mRNA splicing, via spliceosome regulation of RNA splicing RNA processing | chromatin; cytoplasm; extracellular exosome; membrane; nucleoplasm; nucleus; ribonucleoprotein complex; ribonucleoprotein granule | mRNA binding pre-mRNA intronic binding RNA binding transcription cis-regulatory region binding | Homo sapiens | 3D-structure Acetylation Alternative splicing Cytoplasm Direct protein sequencing Isopeptide bond Methylation Nucleus Phosphoprotein Reference proteome Repeat Ribonucleoprotein RNA-binding Ubl conjugation | MSRRLLPRAE | MSRRLLPRAEKRRRRLEQRQQPDEQRRRSGAMVKMAAAGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGGGENYDDPHKTPASPVVHIRGLIDGVVEADLVEALQEFGPISYVVVMPKKRQALVEFEDVLGACNAVNYAADNQIYIAGHPAFVNYSTSQKISRPGDSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRKNGVQAMVEFDSVQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQDTWDYTNPNLSGQGDPGSNPNKRQRQPPLLGDHPAEYGGP... | mRNA processing negative regulation of DNA-templated transcription regulation of alternative mRNA splicing, via spliceosome regulation of RNA splicing RNA processing chromatin; cytoplasm; extracellular exosome; membrane; nucleoplasm; nucleus; ribonucleoprotein complex; ribonucleoprotein granule mRNA binding pre-mRNA in... |
chloride transmembrane transport gamma-aminobutyric acid signaling pathway inhibitory synapse assembly regulation of postsynaptic membrane potential synaptic transmission, GABAergic | chloride channel complex; cytoplasmic vesicle membrane; dendrite membrane; GABA receptor complex; GABA-A receptor complex; GABA-ergic synapse; neuron projection; plasma membrane; postsynapse; postsynaptic membrane; synapse | GABA-A receptor activity GABA-gated chloride ion channel activity inhibitory extracellular ligand-gated monoatomic ion channel activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | Homo sapiens | 3D-structure Cell membrane Chloride Chloride channel Cytoplasmic vesicle Disease variant Disulfide bond Epilepsy Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MRKSPGLSDC | MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVC... | chloride transmembrane transport gamma-aminobutyric acid signaling pathway inhibitory synapse assembly regulation of postsynaptic membrane potential synaptic transmission, GABAergic chloride channel complex; cytoplasmic vesicle membrane; dendrite membrane; GABA receptor complex; GABA-A receptor complex; GABA-ergic syna... |
aspartyl-tRNA aminoacylation protein-containing complex assembly translation | aminoacyl-tRNA synthetase multienzyme complex; cytoplasm; cytosol; extracellular exosome; membrane; synapse | aminoacylase activity aspartate-tRNA ligase activity ATP binding RNA binding | Homo sapiens | 3D-structure Acetylation Alternative splicing Aminoacyl-tRNA synthetase ATP-binding Cytoplasm Disease variant Ligase Nucleotide-binding Phosphoprotein Protein biosynthesis Reference proteome | MPSASASRKS | MPSASASRKSQEKPREIMDAAEDYAKERYGISSMIQSQEKPDRVLVRVRDLTIQKADEVVWVRARVHTSRAKGKQCFLVLRQQQFNVQALVAVGDHASKQMVKFAANINKESIVDVEGVVRKVNQKIGSCTQQDVELHVQKIYVISLAEPRLPLQLDDAVRPEAEGEEEGRATVNQDTRLDNRVIDLRTSTSQAVFRLQSGICHLFRETLINKGFVEIQTPKIISAASEGGANVFTVSYFKNNAYLAQSPQLYKQMCICADFEKVFSIGPVFRAEDSNTHRHLTEFVGLDIEMAFNYHYHEVMEEIADTMVQIFKGLQER... | aspartyl-tRNA aminoacylation protein-containing complex assembly translation aminoacyl-tRNA synthetase multienzyme complex; cytoplasm; cytosol; extracellular exosome; membrane; synapse aminoacylase activity aspartate-tRNA ligase activity ATP binding RNA binding Homo sapiens 3D-structure Acetylation Alternative splicing... |
cellular response to cAMP cellular response to interleukin-4 cellular response to phorbol 13-acetate 12-myristate cellular response to Thyroid stimulating hormone cytoplasmic translation lactation response to selenium ion ribosome biogenesis | cytoplasm; cytoplasmic ribonucleoprotein granule; cytosol; cytosolic large ribosomal subunit; cytosolic ribosome; dendrite; endoplasmic reticulum; nucleus; postsynapse; postsynaptic density; ribonucleoprotein complex; synapse | large ribosomal subunit rRNA binding peptide binding structural constituent of ribosome | Mus musculus | 3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Nucleus Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation | MPREDRATWK | MPREDRATWKSNYFLKIIQLLDDYPKCFIVGADNVGSKQMQQIRMSLRGKAVVLMGKNTMMRKAIRGHLENNPALEKLLPHIRGNVGFVFTKEDLTEIRDMLLANKVPAAARAGAIAPCEVTVPAQNTGLGPEKTSFFQALGITTKISRGTIEILSDVQLIKTGDKVGASEATLLNMLNISPFSFGLIIQQVFDNGSIYNPEVLDITEQALHSRFLEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETEYTFPLTEKVKAFLADPSAFAAAAPAAAATTAAPAAAAAPAKAEAKEESEESDEDMGFGLFD | cellular response to cAMP cellular response to interleukin-4 cellular response to phorbol 13-acetate 12-myristate cellular response to Thyroid stimulating hormone cytoplasmic translation lactation response to selenium ion ribosome biogenesis cytoplasm; cytoplasmic ribonucleoprotein granule; cytosol; cytosolic large rib... |
amino acid catabolic process fatty acid catabolic process | catalytic complex; mitochondrial matrix; mitochondrion | ATP binding enzyme binding metal ion binding propionyl-CoA carboxylase activity | Rattus norvegicus | Acetylation ATP-binding Biotin Direct protein sequencing Ligase Lipid degradation Lipid metabolism Magnesium Manganese Metal-binding Mitochondrion Nucleotide-binding Phosphoprotein Reference proteome Transit peptide | MAGLWVRTVA | MAGLWVRTVALLAARRHWRRSSQQLLWTLKRAPRSSQQLLWTLKRAPVYSQQCLVVSRSLSSVEYEPKEKTFDKILIANRGEIACRVIKTCRKMGIRTVAIHSDVDASSVHVKMADEAVCVGPAPTSKSYLNMDAIMEAIKKTGAQAVHPGYGFLSENKEFAKCLAAEDVTFIGPDTHAIQAMGDKIESKLLAKRAKVNTIPGFDGVLKDADEAVRIAREIGYPVMIKASAGGGGKGMRIPWDDEETRDGFRFSSQEAASSFGDDRLLIEKFIDNPRHIEIQVLGDKHGNALWLNERECSIQRRNQKVVEEAPSIFLDPE... | amino acid catabolic process fatty acid catabolic process catalytic complex; mitochondrial matrix; mitochondrion ATP binding enzyme binding metal ion binding propionyl-CoA carboxylase activity Rattus norvegicus Acetylation ATP-binding Biotin Direct protein sequencing Ligase Lipid degradation Lipid metabolism Magnesium ... |
coenzyme A metabolic process isopentenyl diphosphate biosynthetic process, mevalonate pathway isoprenoid biosynthetic process sterol biosynthetic process | endoplasmic reticulum; endoplasmic reticulum membrane | hydroxymethylglutaryl-CoA reductase (NADPH) activity | Arabidopsis thaliana | 3D-structure Alternative initiation Direct protein sequencing Endoplasmic reticulum Glycoprotein Isoprene biosynthesis Membrane NADP Oxidoreductase Phosphoprotein Reference proteome Transmembrane Transmembrane helix | MDLRRRPPKP | MDLRRRPPKPPVTNNNNSNGSFRSYQPRTSDDDHRRRATTIAPPPKASDALPLPLYLTNAVFFTLFFSVAYYLLHRWRDKIRYNTPLHVVTITELGAIIALIASFIYLLGFFGIDFVQSFISRASGDAWDLADTIDDDDHRLVTCSPPTPIVSVAKLPNPEPIVTESLPEEDEEIVKSVIDGVIPSYSLESRLGDCKRAASIRREALQRVTGRSIEGLPLDGFDYESILGQCCEMPVGYIQIPVGIAGPLLLDGYEYSVPMATTEGCLVASTNRGCKAMFISGGATSTVLKDGMTRAPVVRFASARRASELKFFLENPEN... | coenzyme A metabolic process isopentenyl diphosphate biosynthetic process, mevalonate pathway isoprenoid biosynthetic process sterol biosynthetic process endoplasmic reticulum; endoplasmic reticulum membrane hydroxymethylglutaryl-CoA reductase (NADPH) activity Arabidopsis thaliana 3D-structure Alternative initiation Di... |
cell cycle cell division cell wall organization peptidoglycan biosynthetic process regulation of cell shape | cytoplasm | ATP binding identical protein binding UDP-N-acetylmuramoylalanine-D-glutamate ligase activity | Escherichia coli | 3D-structure ATP-binding Cell cycle Cell division Cell shape Cell wall biogenesis/degradation Cytoplasm Direct protein sequencing Ligase Nucleotide-binding Peptidoglycan synthesis Reference proteome | MADYQGKNVV | MADYQGKNVVIIGLGLTGLSCVDFFLARGVTPRVMDTRMTPPGLDKLPEAVERHTGSLNDEWLMAADLIVASPGIALAHPSLSAAADAGIEIVGDIELFCREAQAPIVAITGSNGKSTVTTLVGEMAKAAGVNVGVGGNIGLPALMLLDDECELYVLELSSFQLETTSSLQAVAATILNVTEDHMDRYPFGLQQYRAAKLRIYENAKVCVVNADDALTMPIRGADERCVSFGVNMGDYHLNHQQGETWLRVKGEKVLNVKEMKLSGQHNYTNALAALALADAAGLPRASSLKALTTFTGLPHRFEVVLEHNGVRWINDSK... | cell cycle cell division cell wall organization peptidoglycan biosynthetic process regulation of cell shape cytoplasm ATP binding identical protein binding UDP-N-acetylmuramoylalanine-D-glutamate ligase activity Escherichia coli 3D-structure ATP-binding Cell cycle Cell division Cell shape Cell wall biogenesis/degradati... |
de novo' NAD biosynthetic process from tryptophan female pregnancy inflammatory response kynurenic acid biosynthetic process multicellular organismal response to stress negative regulation of interleukin-10 production negative regulation of T cell apoptotic process negative regulation of T cell proliferation positive r... | cytoplasm; cytosol; smooth muscle contractile fiber; stereocilium bundle | electron transfer activity heme binding indoleamine 2,3-dioxygenase activity metal ion binding tryptophan 2,3-dioxygenase activity | Homo sapiens | 3D-structure Cytoplasm Dioxygenase Direct protein sequencing Heme Immunity Iron Metal-binding Oxidoreductase Reference proteome Tryptophan catabolism | MAHAMENSWT | MAHAMENSWTISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLESNPSVREFV... | de novo' NAD biosynthetic process from tryptophan female pregnancy inflammatory response kynurenic acid biosynthetic process multicellular organismal response to stress negative regulation of interleukin-10 production negative regulation of T cell apoptotic process negative regulation of T cell proliferation positive r... |
cytoplasm to vacuole transport by the Cvt pathway protein transport proteolysis | Cvt complex; cytoplasm; fungal-type vacuole | identical protein binding metalloaminopeptidase activity zinc ion binding | Saccharomyces cerevisiae | 3D-structure Aminopeptidase Direct protein sequencing Glycoprotein Hydrolase Metal-binding Metalloprotease Phosphoprotein Protease Protein transport Reference proteome Transport Vacuole Zinc Zymogen | MEEQREILEQ | MEEQREILEQLKKTLQMLTVEPSKNNQIANEEKEKKENENSWCILEHNYEDIAQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFYTIRNGTNLSAFILGKNWRAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWLDRDLGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGPFDKEDQTIPVIGFPTPDEEGNEPPTDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELIQMDLDLFDVQKGTIGGIGKHFLFAPRLDDRLCSFAAMIALICYAK... | cytoplasm to vacuole transport by the Cvt pathway protein transport proteolysis Cvt complex; cytoplasm; fungal-type vacuole identical protein binding metalloaminopeptidase activity zinc ion binding Saccharomyces cerevisiae 3D-structure Aminopeptidase Direct protein sequencing Glycoprotein Hydrolase Metal-binding Metal... |
cytosol to endoplasmic reticulum transport post-translational protein targeting to endoplasmic reticulum membrane post-translational protein targeting to membrane, translocation SRP-dependent cotranslational protein targeting to membrane | endoplasmic reticulum; mitochondrion; nuclear inner membrane; rough endoplasmic reticulum membrane; Sec62/Sec63 complex; translocon complex | protein transmembrane transporter activity | Saccharomyces cerevisiae | 3D-structure Chaperone Endoplasmic reticulum Membrane Nucleus Phosphoprotein Protein transport Reference proteome Repeat Transmembrane Transmembrane helix Transport | MPTNYEYDEA | MPTNYEYDEASETWPSFILTGLLMVVGPMTLLQIYQIFFGANAEDGNSGKSKEFNEEVFKNLNEEYTSDEIKQFRRKFDKNSNKKSKIWSRRNIIIIVGWILVAILLQRINSNDAIKDAATKLFDPYEILGISTSASDRDIKSAYRKLSVKFHPDKLAKGLTPDEKSVMEETYVQITKAYESLTDELVRQNYLKYGHPDGPQSTSHGIALPRFLVDGSASPLLVVCYVALLGLILPYFVSRWWARTQSYTKKGIHNVTASNFVSNLVNYKPSEIVTTDLILHWLSFAHEFKQFFPDLQPTDFEKLLQDHINRRDSGKLNN... | cytosol to endoplasmic reticulum transport post-translational protein targeting to endoplasmic reticulum membrane post-translational protein targeting to membrane, translocation SRP-dependent cotranslational protein targeting to membrane endoplasmic reticulum; mitochondrion; nuclear inner membrane; rough endoplasmic re... |
ncRNA export from nucleus NLS-bearing protein import into nucleus nucleocytoplasmic transport poly(A)+ mRNA export from nucleus protein import into nucleus ribosomal large subunit export from nucleus ribosomal small subunit export from nucleus RNA export from nucleus tRNA export from nucleus | nuclear envelope; nuclear membrane; nuclear periphery; nuclear pore; nuclear pore central transport channel; nuclear pore nuclear basket | molecular adaptor activity phospholipid binding structural constituent of nuclear pore | Saccharomyces cerevisiae | 3D-structure Coiled coil Membrane mRNA transport Nuclear pore complex Nucleus Phosphoprotein Protein transport Reference proteome Repeat Translocation Transport | MNFNTPQQNK | MNFNTPQQNKTPFSFGTANNNSNTTNQNSSTGAGAFGTGQSTFGFNNSAPNNTNNANSSITPAFGSNNTGNTAFGNSNPTSNVFGSNNSTTNTFGSNSAGTSLFGSSSAQQTKSNGTAGGNTFGSSSLFNNSTNSNTTKPAFGGLNFGGGNNTTPSSTGNANTSNNLFGATANANKPAFSFGATTNDDKKTEPDKPAFSFNSSVGNKTDAQAPTTGFSFGSQLGGNKTVNEAAKPSLSFGSGSAGANPAGASQPEPTTNEPAKPALSFGTATSDNKTTNTTPSFSFGAKSDENKAGATSKPAFSFGAKPEEKKDDNSSKP... | ncRNA export from nucleus NLS-bearing protein import into nucleus nucleocytoplasmic transport poly(A)+ mRNA export from nucleus protein import into nucleus ribosomal large subunit export from nucleus ribosomal small subunit export from nucleus RNA export from nucleus tRNA export from nucleus nuclear envelope; nuclear m... |
methylation mitochondrial transcription positive regulation of DNA-templated transcription, elongation transcription initiation at mitochondrial promoter | mitochondrial DNA-directed RNA polymerase complex; mitochondrial intermembrane space; mitochondrial matrix; mitochondrion | DNA binding methyltransferase activity mitochondrial transcription factor activity RNA binding | Saccharomyces cerevisiae | 3D-structure Direct protein sequencing DNA-binding Methyltransferase Mitochondrion Reference proteome RNA-binding S-adenosyl-L-methionine Transcription Transcription regulation Transferase | MSVPIPGIKD | MSVPIPGIKDISKLKFFYGFKYLWNPTVYNKIFDKLDLTKTYKHPEELKVLDLYPGVGIQSAIFYNKYCPRQYSLLEKRSSLYKFLNAKFEGSPLQILKRDPYDWSTYSNLIDEERIFVPEVQSSDHINDKFLTVANVTGEGSEGLIMQWLSCIGNKNWLYRFGKVKMLLWMPSTTARKLLARPGMHSRSKCSVVREAFTDTKLIAISDANELKGFDSQCIEEWDPILFSAAEIWPTKGKPIALVEMDPIDFDFDVDNWDYVTRHLMILKRTPLNTVMDSLGHGGQQYFNSRITDKDLLKKCPIDLTNDEFIYLTKLFME... | methylation mitochondrial transcription positive regulation of DNA-templated transcription, elongation transcription initiation at mitochondrial promoter mitochondrial DNA-directed RNA polymerase complex; mitochondrial intermembrane space; mitochondrial matrix; mitochondrion DNA binding methyltransferase activity mitoc... |
urea catabolic process | urease complex | nickel cation binding urease activity | Helicobacter pylori | 3D-structure Cytoplasm Direct protein sequencing Hydrolase Reference proteome Virulence | MKLTPKELDK | MKLTPKELDKLMLHYAGELAKKRKEKGIKLNYVEAVALISAHIMEEARAGKKTAAELMQEGRTLLKPDDVMDGVASMIHEVGIEAMFPDGTKLVTVHTPIEANGKLVPGELFLKNEDITINEGKKAVSVKVKNVGDRPVQIGSHFHFFEVNRCLDFDREKTFGKRLDIASGTAVRFEPGEEKSVELIDIGGNRRIFGFNALVDRQADNESKKIALHRAKERGFHGAKSDDNYVKTIKE | urea catabolic process urease complex nickel cation binding urease activity Helicobacter pylori 3D-structure Cytoplasm Direct protein sequencing Hydrolase Reference proteome Virulence MKLTPKELDK MKLTPKELDKLMLHYAGELAKKRKEKGIKLNYVEAVALISAHIMEEARAGKKTAAELMQEGRTLLKPDDVMDGVASMIHEVGIEAMFPDGTKLVTVHTPIEANGKLVPGELFLKNEDITINEGK... |
D-alanine catabolic process D-amino acid catabolic process D-serine catabolic process D-serine metabolic process digestion dopamine biosynthetic process proline catabolic process | cytoplasm; cytosol; peroxisomal matrix | D-amino-acid oxidase activity FAD binding identical protein binding | Homo sapiens | 3D-structure FAD Flavoprotein Oxidoreductase Peroxisome Reference proteome Schizophrenia | MRVVVIGAGV | MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPNNPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPRELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVNCTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGGIFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGPSNTEVIHNYGHGGYGLTIHW... | D-alanine catabolic process D-amino acid catabolic process D-serine catabolic process D-serine metabolic process digestion dopamine biosynthetic process proline catabolic process cytoplasm; cytosol; peroxisomal matrix D-amino-acid oxidase activity FAD binding identical protein binding Homo sapiens 3D-structure FAD Flav... |
cell motility immune response negative regulation of cell cycle negative regulation of cell population proliferation PML body organization positive regulation of angiogenesis positive regulation of blood vessel endothelial cell migration positive regulation of DNA-templated transcription positive regulation of endothel... | chromatin; cytoplasm; nucleoplasm; nucleus | DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific identical protein binding nuclear receptor coactivator activity nucleic acid binding RNA polymerase II cis-regulatory regio... | Homo sapiens | 3D-structure Acetylation Alternative splicing Cytoplasm DNA-binding Immunity Isopeptide bond Nucleus Phosphoprotein Proto-oncogene Reference proteome Transcription Transcription regulation Ubl conjugation | MKAAVDLKPT | MKAAVDLKPTLTIIKTEKVDLELFPSPDMECADVPLLTPSSKEMMSQALKATFSGFTKEQQRLGIPKDPRQWTETHVRDWVMWAVNEFSLKGVDFQKFCMNGAALCALGKDCFLELAPDFVGDILWEHLEILQKEDVKPYQVNGVNPAYPESRYTSDYFISYGIEHAQCVPPSEFSEPSFITESYQTLHPISSEELLSLKYENDYPSVILRDPLQTDTLQNDYFAIKQEVVTPDNMCMGRTSRGKLGGQDSFESIESYDSCDRLTQSWSSQSSFNSLQRVPSYDSFDSEDYPAALPNHKPKGTFKDYVRDRADLNKDKPV... | cell motility immune response negative regulation of cell cycle negative regulation of cell population proliferation PML body organization positive regulation of angiogenesis positive regulation of blood vessel endothelial cell migration positive regulation of DNA-templated transcription positive regulation of endothel... |
chromatin remodeling hyperosmotic response negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II | nucleus; transcription repressor complex | chromatin DNA binding histone deacetylase binding RNA polymerase II cis-regulatory region sequence-specific DNA binding transcription coactivator activity transcription corepressor activity | Saccharomyces cerevisiae | Amyloid Nucleus Phosphoprotein Prion Reference proteome Repeat Repressor TPR repeat Transcription Transcription regulation | MNPGGEQTIM | MNPGGEQTIMEQPAQQQQQQQQQQQQQQQQAAVPQQPLDPLTQSTAETWLSIASLAETLGDGDRAAMAYDATLQFNPSSAKALTSLAHLYRSRDMFQRAAELYERALLVNPELSDVWATLGHCYLMLDDLQRAYNAYQQALYHLSNPNVPKLWHGIGILYDRYGSLDYAEEAFAKVLELDPHFEKANEIYFRLGIIYKHQGKWSQALECFRYILPQPPAPLQEWDIWFQLGSVLESMGEWQGAKEAYEHVLAQNQHHAKVLQQLGCLYGMSNVQFYDPQKALDYLLKSLEADPSDATTWYHLGRVHMIRTDYTAAYDAFQ... | chromatin remodeling hyperosmotic response negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II nucleus; transcription repressor complex chromatin DNA bindin... |
bundle of His cell-Purkinje myocyte adhesion involved in cell communication canonical Wnt signaling pathway cell migration cell-cell adhesion cellular response to indole-3-methanol desmosome assembly detection of mechanical stimulus endothelial cell-cell adhesion negative regulation of blood vessel endothelial cell mig... | adherens junction; catenin complex; cell-cell junction; cornified envelope; cytoplasm; cytoplasmic side of plasma membrane; cytoskeleton; cytosol; desmosome; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; focal adhesion; gamma-catenin-TCF7L2 complex; intercalated disc; intermediate filament;... | alpha-catenin binding cadherin binding cell adhesion molecule binding cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication cytoskeletal protein-membrane anchor activity DNA-binding transcription factor binding protein homodimerization activity protein phosphatase binding structura... | Homo sapiens | 3D-structure Acetylation Cardiomyopathy Cell adhesion Cell junction Cytoplasm Cytoskeleton Direct protein sequencing Disease variant Glycoprotein Membrane Palmoplantar keratoderma Phosphoprotein Reference proteome Repeat | MEVMNLMEQP | MEVMNLMEQPIKVTEWQQTYTYDSGIHSGANTCVPSVSSKGIMEEDEACGRQYTLKKTTTYTQGVPPSQGDLEYQMSTTARAKRVREAMCPGVSGEDSSLLLATQVEGQATNLQRLAEPSQLLKSAIVHLINYQDDAELATRALPELTKLLNDEDPVVVTKAAMIVNQLSKKEASRRALMGSPQLVAAVVRTMQNTSDLDTARCTTSILHNLSHHREGLLAIFKSGGIPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAITTDCLQLLAYGNQESKLIILANGGPQALVQIMR... | bundle of His cell-Purkinje myocyte adhesion involved in cell communication canonical Wnt signaling pathway cell migration cell-cell adhesion cellular response to indole-3-methanol desmosome assembly detection of mechanical stimulus endothelial cell-cell adhesion negative regulation of blood vessel endothelial cell mig... |
fatty acid primary amide biosynthetic process heart development lactation limb development long-chain fatty acid metabolic process maternal process involved in female pregnancy mitotic chromosome condensation ovulation cycle process peptide amidation peptide metabolic process regulation of actin cytoskeleton organizati... | cell surface; chromatin; condensed chromosome; extracellular region; extracellular space; neuronal cell body; perikaryon; perinuclear region of cytoplasm; secretory granule; trans-Golgi network; transport vesicle membrane | calcium ion binding chromatin binding copper ion binding identical protein binding L-ascorbic acid binding peptidylamidoglycolate lyase activity peptidylglycine monooxygenase activity protein kinase binding zinc ion binding | Rattus norvegicus | 3D-structure Alternative splicing Calcium Cleavage on pair of basic residues Copper Cytoplasmic vesicle Direct protein sequencing Disulfide bond Glycoprotein Lipid metabolism Lyase Membrane Metal-binding Monooxygenase Multifunctional enzyme Oxidoreductase Phosphoprotein Reference proteome Repeat Signal Sulfation Transm... | MAGRARSGLL | MAGRARSGLLLLLLGLLALQSSCLAFRSPLSVFKRFKETTRSFSNECLGTIGPVTPLDASDFALDIRMPGVTPKESDTYFCMSMRLPVDEEAFVIDFKPRASMDTVHHMLLFGCNMPSSTGSYWFCDEGTCTDKANILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNHKDCSGVSVHLTRVPQPLIAGMYLMMSVDTVIPPGEKVVNADISCQYKMYPMHVFAYRVHTHHLGKVVSGYRVRNGQWTLIGRQNPQLPQAFYPVEHPVDVTFGDILAARCVFTGEGRTEATHIGGTSSDEMCNLYIM... | fatty acid primary amide biosynthetic process heart development lactation limb development long-chain fatty acid metabolic process maternal process involved in female pregnancy mitotic chromosome condensation ovulation cycle process peptide amidation peptide metabolic process regulation of actin cytoskeleton organizati... |
cellular response to lithium ion glutathione metabolic process response to herbicide response to nicotine response to zinc ion xenobiotic metabolic process | cytoplasm | glutathione transferase activity identical protein binding organic cyclic compound binding protein homodimerization activity toxic substance binding | Rattus norvegicus | Acetylation Cytoplasm Direct protein sequencing Reference proteome Transferase | MEVKPKLYYF | MEVKPKLYYFQGRGRMESIRWLLATAGVEFEEEFLETREQYEKLQKDGCLLFGQVPLVEIDGMLLTQTRAILSYLAAKYNLYGKDLKERVRIDMYADGTQDLMMMIIGAPFKAPQEKEESLALAVKRAKNRYFPVFEKILKDHGEAFLVGNQLSWADIQLLEAILMVEEVSAPVLSDFPLLQAFKTRISNIPTIKKFLQPGSQRKPPPDGHYVDVVRTVLKF | cellular response to lithium ion glutathione metabolic process response to herbicide response to nicotine response to zinc ion xenobiotic metabolic process cytoplasm glutathione transferase activity identical protein binding organic cyclic compound binding protein homodimerization activity toxic substance binding Rattu... |
lipid metabolic process | endoplasmic reticulum lumen | carboxylesterase activity | Oryctolagus cuniculus | Direct protein sequencing Disulfide bond Endoplasmic reticulum Glycoprotein Hydrolase Lipid metabolism Pyrrolidone carboxylic acid Reference proteome Serine esterase | QDSASPIRNT | QDSASPIRNTHTGQVRGSLVHVEGTDAGVHTFLGIPFAKPPLGPLRFAPPEPAEAWSGVRDGTSLPAMCLQNLAIMDQDVLLLHFTPPSIPMSEDCLYLNIYSPAHAREGSDLPVMVWIHGGGLTMGMASMYDGSALAAFEDVVVVTIQYRLGVLGFFSTGDQHATGNHGYLDQVAALRWVQKNIAHFGGNPGRVTIFGESAGGTSVSSHVLSPMSQGLFHGAIMESLVALLPGLITSSSEVVSTVVANLSRCGQVDSETLVRCLRAKSEEEMLAITQVFMLIPGVVDGVFLPRHPEELLALADFQPVPSIIGINNDEYG... | lipid metabolic process endoplasmic reticulum lumen carboxylesterase activity Oryctolagus cuniculus Direct protein sequencing Disulfide bond Endoplasmic reticulum Glycoprotein Hydrolase Lipid metabolism Pyrrolidone carboxylic acid Reference proteome Serine esterase QDSASPIRNT QDSASPIRNTHTGQVRGSLVHVEGTDAGVHTFLGIPFAKPPLG... |
permeabilization of host organelle membrane involved in viral entry into host cell protein complex oligomerization viral entry via permeabilization of inner membrane viral penetration into host nucleus virion attachment to host cell virus-mediated pore formation in host cell membrane | host cell endoplasmic reticulum membrane; host cell nucleus; membrane; viral capsid | DNA binding monoatomic ion channel activity structural molecule activity | BK polyomavirus | Alternative initiation Alternative splicing Capsid protein DNA-binding Host endoplasmic reticulum Host membrane Host nucleus Host-virus interaction Ion channel Ion transport Late protein Lipoprotein Membrane Myristate Transmembrane Transmembrane helix Transport Viral attachment to host cell Viral ion channel Viral pene... | MGAALALLGD | MGAALALLGDLVASVSEAAAATGFSVAEIAAGEAAAAIEVQIASLATVEGITTTSEAIAAIGLTPQTYAVIAGAPGAIAGFAALIQTVTGISSLAQVGYRFFSDWDHKVSTVGLYQQSGMALELFNPDEYYDILFPGVNTFVNNIQYLDPRHWGPSLFATISQALWHVIRDDIPAITSQELQRRTERFFRDSLARFLEETTWTIVNAPINFYNYIQDYYSNLSPIRPSMVRQVAEREGTHVNFGHTYSIDNADSIEEVTQRMDLRNKESVHSGEFIEKTIAPGGANQRTAPQWMLPLLLGLYGTVTPALEAYEDGPNQKK... | permeabilization of host organelle membrane involved in viral entry into host cell protein complex oligomerization viral entry via permeabilization of inner membrane viral penetration into host nucleus virion attachment to host cell virus-mediated pore formation in host cell membrane host cell endoplasmic reticulum mem... |
DNA catabolic process DNA restriction-modification system | endonuclease complex | ATP binding ATP hydrolysis activity DNA binding double-stranded methylated DNA binding endonuclease activity GTP binding GTPase activity hemi-methylated DNA-binding identical protein binding restriction endodeoxyribonuclease activity | Escherichia coli | 3D-structure Alternative initiation Direct protein sequencing DNA-binding Endonuclease GTP-binding Hydrolase Nuclease Nucleotide-binding Reference proteome Restriction system | MESIQPWIEK | MESIQPWIEKFIKQAQQQRSQSTKDYPTSYRNLRVKLSFGYGNFTSIPWFAFLGEGQEASNGIYPVILYYKDFDELVLAYGISDTNEPHAQWQFSSDIPKTIAEYFQATSGVYPKKYGQSYYACSQKVSQGIDYTRFASMLDNIINDYKLIFNSGKSVIPPMSKTESYCLEDALNDLFIPETTIETILKRLTIKKNIILQGPPGVGKTFVARRLAYLLTGEKAPQRVNMVQFHQSYSYEDFIQGYRPNGVGFRRKDGIFYNFCQQAKEQPEKKYIFIIDEINRANLSKVFGEVMMLMEHDKRGENWSVPLTYSENDEERF... | DNA catabolic process DNA restriction-modification system endonuclease complex ATP binding ATP hydrolysis activity DNA binding double-stranded methylated DNA binding endonuclease activity GTP binding GTPase activity hemi-methylated DNA-binding identical protein binding restriction endodeoxyribonuclease activity Escheri... |
carbohydrate metabolic process pentose-phosphate shunt pentose-phosphate shunt, non-oxidative branch | cytoplasm; nucleus | transaldolase activity | Saccharomyces cerevisiae | Acetylation Pentose shunt Reference proteome Schiff base Transferase | MSEPAQKKQK | MSEPAQKKQKVANNSLEQLKASGTVVVADTGDFGSIAKFQPQDSTTNPSLILAAAKQPTYAKLIDVAVEYGKKHGKTTEEQVENAVDRLLVEFGKEILKIVPGRVSTEVDARLSFDTQATIEKARHIIKLFEQEGVSKERVLIKIASTWEGIQAAKELEEKDGIHCNLTLLFSFVQAVACAEAQVTLISPFVGRILDWYKSSTGKDYKGEADPGVISVKKIYNYYKKYGYKTIVMGASFRSTDEIKNLAGVDYLTISPALLDKLMNSTEPFPRVLDPVSAKKEAGDKISYISDESKFRFDLNEDAMATEKLSEGIRKFSA... | carbohydrate metabolic process pentose-phosphate shunt pentose-phosphate shunt, non-oxidative branch cytoplasm; nucleus transaldolase activity Saccharomyces cerevisiae Acetylation Pentose shunt Reference proteome Schiff base Transferase MSEPAQKKQK MSEPAQKKQKVANNSLEQLKASGTVVVADTGDFGSIAKFQPQDSTTNPSLILAAAKQPTYAKLIDVAVEYG... |
intracellular iron ion homeostasis iron import into cell siderophore-dependent iron import into cell | ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; membrane; plasma membrane | iron chelate transmembrane transporter activity transmembrane transporter activity | Escherichia coli | Cell inner membrane Cell membrane Ion transport Iron Iron transport Membrane Reference proteome Transmembrane Transmembrane helix Transport | MKIALVIFIT | MKIALVIFITLALAGCALLSLHMGVIPVPWRALLTDWQAGHEHYYVLMEYRLPRLLLALFVGAALAVAGVLIQGIVRNPLASPDILGVNHAASLASVGALLLMPSLPVMVLPLLAFAGGMAGLILLKMLAKTHQPMKLALTGVALSACWASLTDYLMLSRPQDVNNALLWLTGSLWGRDWSFVKIAIPLMILFLPLSLSFCRDLDLLALGDARATTLGVSVPHTRFWALLLAVAMTSTGVAACGPISFIGLVVPHMMRSITGGRHRRLLPVSALTGALLLVVADLLARIIHPPLELPVGVLTAIIGAPWFVWLLVRMR | intracellular iron ion homeostasis iron import into cell siderophore-dependent iron import into cell ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; membrane; plasma membrane iron chelate transmembrane transporter activity transmembrane transporter activity Escherichia coli Cell in... |
intracellular iron ion homeostasis iron import into cell siderophore-dependent iron import into cell | ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; membrane; plasma membrane | iron chelate transmembrane transporter activity transmembrane transporter activity | Escherichia coli | Cell inner membrane Cell membrane Ion transport Iron Iron transport Membrane Reference proteome Transmembrane Transmembrane helix Transport | MTAIKHPVLL | MTAIKHPVLLWGLPVAALIIIFWLSLFCYSAIPVSGADATRALLPGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGTLLQTLTHNPMASPSLLGINSGAALAMALTSALSPTPIAGYSLSFIAACGGGVSWLLVMTAGGGFRHTHDRNKLILAGIALSAFCMGLTRITLLLAEDHAYGIFYWLAGGVSHARWQDVWQLLPVVVTAVPVVLLLANQLNLLNLSDSTAHTLGVNLTRLRLVINMLVLLLVGACVSVAGPVAFIGLLVPHLARFWAGFDQRNVLPVSMLLGATLMLLADVLARALAFPGDLPAGAVLALIG... | intracellular iron ion homeostasis iron import into cell siderophore-dependent iron import into cell ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; membrane; plasma membrane iron chelate transmembrane transporter activity transmembrane transporter activity Escherichia coli Cell in... |
protein homotetramerization proteolysis | cytosol; protein-containing complex | aminopeptidase activity identical protein binding manganese ion binding metalloaminopeptidase activity metalloexopeptidase activity | Escherichia coli | 3D-structure Aminopeptidase Cytoplasm Direct protein sequencing Hydrolase Manganese Metal-binding Metalloprotease Protease Reference proteome | MSEISRQEFQ | MSEISRQEFQRRRQALVEQMQPGSAALIFAAPEVTRSADSEYPYRQNSDFWYFTGFNEPEAVLVLIKSDDTHNHSVLFNRVRDLTAEIWFGRRLGQDAAPEKLGVDRALAFSEINQQLYQLLNGLDVVYHAQGEYAYADVIVNSALEKLRKGSRQNLTAPATMIDWRPVVHEMRLFKSPEEIAVLRRAGEITAMAHTRAMEKCRPGMFEYHLEGEIHHEFNRHGARYPSYNTIVGSGENGCILHYTENECEMRDGDLVLIDAGCEYKGYAGDITRTFPVNGKFTQAQREIYDIVLESLETSLRLYRPGTSILEVTGEVVR... | protein homotetramerization proteolysis cytosol; protein-containing complex aminopeptidase activity identical protein binding manganese ion binding metalloaminopeptidase activity metalloexopeptidase activity Escherichia coli 3D-structure Aminopeptidase Cytoplasm Direct protein sequencing Hydrolase Manganese Metal-bindi... |
ectodermal cell fate commitment mesoderm development negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II primitive streak formation regulation of transcription by RNA polymerase II skeletal system development | chromatin; cytosol; nucleoplasm; nucleus; plasma membrane | DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific nuclear glucocorticoid receptor binding protein domain specific binding RNA polymerase II cis-regulatory region sequence-sp... | Homo sapiens | 3D-structure DNA-binding Nucleus Phosphoprotein Proto-oncogene Reference proteome Transcription Transcription regulation | MNDFGIKNMD | MNDFGIKNMDQVAPVANSYRGTLKRQPAFDTFDGSLFAVFPSLNEEQTLQEVPTGLDSISHDSANCELPLLTPCSKAVMSQALKATFSGFKKEQRRLGIPKNPWLWSEQQVCQWLLWATNEFSLVNVNLQRFGMNGQMLCNLGKERFLELAPDFVGDILWEHLEQMIKENQEKTEDQYEENSHLTSVPHWINSNTLGFGTEQAPYGMQTQNYPKGGLLDSMCPASTPSVLSSEQEFQMFPKSRLSSVSVTYCSVSQDFPGSNLNLLTNNSGTPKDHDSPENGADSFESSDSLLQSWNSQSSLLDVQRVPSFESFEDDCSQ... | ectodermal cell fate commitment mesoderm development negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II primitive streak formation regulation of transcription by RNA polymerase II skeletal system development chromatin; cytosol; nucleoplasm; nucleus; plasm... |
ectodermal cell fate commitment mesoderm development negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II primitive streak formation regulation of transcription by RNA polymerase II | cytosol; nucleoplasm; nucleus; plasma membrane | DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific nuclear glucocorticoid receptor binding protein domain specific binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II trans... | Mus musculus | DNA-binding Nucleus Phosphoprotein Proto-oncogene Reference proteome Transcription Transcription regulation | MNDFGIKNMD | MNDFGIKNMDQVAPVANSFRGTLKRQPAFDTFDGSLFAVLPSLSEDQTLQEVPTGLDSVSHDSASCELPLLTPCSKAVMSQALKATFSGFQKEQRRLGIPKNPWLWSEQQVCQWLLWATNEFSLVNVNLHQFGMNGQMLCNLGKERFLELAPDFVGDILWEHLEQMIKENQEKTEDQYEENSHLNAVPHWINSNTLGFSMEQAPYGMQAPNYPKDNLLDSMCPPSATPAALGSELQMLPKSRLNTVNVNYCSISQDFPSSNVNLLNNNSGKPKDHDSPENGGDSFESSDSLLRSWNSQSSLLDVQRVPSFESFEEDCSQS... | ectodermal cell fate commitment mesoderm development negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II primitive streak formation regulation of transcription by RNA polymerase II cytosol; nucleoplasm; nucleus; plasma membrane DNA binding DNA-binding tran... |
base-excision repair, DNA ligation DNA ligation DNA replication | cytosol | DNA binding DNA ligase (NAD+) activity metal ion binding NAD+ binding | Escherichia coli | 3D-structure Direct protein sequencing DNA damage DNA repair DNA replication Ligase Magnesium Metal-binding NAD Reference proteome Zinc | MESIEQQLTE | MESIEQQLTELRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRELETKHPELITPDSPTQRVGAAPLAAFSQIRHEVPMLSLDNVFDEESFLAFNKRVQDRLKNNEKVTWCCELKLDGLAVSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLHGENIPARLEVRGEVFLPQAGFEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGVLEGGELPDTHLGRLLQFKKWGLPVSDRVTLCESAEEVLAFYHKVEEDRPTLGFDIDGVVIKVNSLAQQEQLGFVARAPRWAVAFKFPAQEQ... | base-excision repair, DNA ligation DNA ligation DNA replication cytosol DNA binding DNA ligase (NAD+) activity metal ion binding NAD+ binding Escherichia coli 3D-structure Direct protein sequencing DNA damage DNA repair DNA replication Ligase Magnesium Metal-binding NAD Reference proteome Zinc MESIEQQLTE MESIEQQLTELRTT... |
DNA damage response DNA duplex unwinding DNA recombination DNA repair DNA replication SOS response | bacterial nucleoid; chromosome; cytoplasm; replisome; single-stranded DNA-dependent ATP-dependent DNA helicase complex | 3'-5' DNA helicase activity ATP binding ATP hydrolysis activity ATP-dependent activity, acting on DNA DNA binding DNA helicase activity four-way junction helicase activity single-stranded DNA helicase activity transition metal ion binding zinc ion binding | Escherichia coli | 3D-structure ATP-binding Direct protein sequencing DNA damage DNA recombination DNA repair DNA-binding Helicase Hydrolase Nucleotide-binding Reference proteome SOS response | MAQAEVLNLE | MAQAEVLNLESGAKQVLQETFGYQQFRPGQEEIIDTVLSGRDCLVVMPTGGGKSLCYQIPALLLNGLTVVVSPLISLMKDQVDQLQANGVAAACLNSTQTREQQLEVMTGCRTGQIRLLYIAPERLMLDNFLEHLAHWNPVLLAVDEAHCISQWGHDFRPEYAALGQLRQRFPTLPFMALTATADDTTRQDIVRLLGLNDPLIQISSFDRPNIRYMLMEKFKPLDQLMRYVQEQRGKSGIIYCNSRAKVEDTAARLQSKGISAAAYHAGLENNVRADVQEKFQRDDLQIVVATVAFGMGINKPNVRFVVHFDIPRNIESY... | DNA damage response DNA duplex unwinding DNA recombination DNA repair DNA replication SOS response bacterial nucleoid; chromosome; cytoplasm; replisome; single-stranded DNA-dependent ATP-dependent DNA helicase complex 3'-5' DNA helicase activity ATP binding ATP hydrolysis activity ATP-dependent activity, acting on DNA ... |
enterobactin biosynthetic process | cytosol; protein-containing complex | 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity identical protein binding | Escherichia coli | 3D-structure Direct protein sequencing Enterobactin biosynthesis NAD Oxidoreductase Reference proteome | MDFSGKNVWV | MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVVDGGSTLGA | enterobactin biosynthetic process cytosol; protein-containing complex 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity identical protein binding Escherichia coli 3D-structure Direct protein sequencing Enterobactin biosynthesis NAD Oxidoreductase Reference proteome MDFSGKNVWV MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFD... |
cellular response to calcium ion gene expression negative regulation of transcription by RNA polymerase II osteoblast development positive regulation of macrophage activation positive regulation of osteoblast differentiation positive regulation of transcription by RNA polymerase II regulation of cell cycle regulation o... | nucleoplasm; nucleus; protein-containing complex; protein-DNA complex; RNA polymerase II transcription regulator complex; transcription factor AP-1 complex; transcription regulator complex; transcription repressor complex | DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific double-stranded DNA binding enzyme binding nuclear receptor binding RNA polymerase II cis-regulatory region sequence-specif... | Mus musculus | Disulfide bond DNA-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | METPFYGEEA | METPFYGEEALSGLAAGASSVAGATGAPGGGGFAPPGRAFPGAPPTSSMLKKDALTLSLAEQGAAGLKPGSATAPSALRPDGAPDGLLASPDLGLLKLASPELERLIIQSNGLVTTTPTSTQFLYPKVAASEEQEFAEGFVKALEDLHKQSQLGAATAATSGAPAPPAPADLAATPGATETPVYANLSSFAGGAGPPGGAATVAFAAEPVPFPPPPGALGPPPPPHPPRLAALKDEPQTVPDVPSFGDSPPLSPIDMDTQERIKAERKRLRNRIAASKCRKRKLERISRLEEKVKTLKSQNTELASTASLLREQVAQLKQ... | cellular response to calcium ion gene expression negative regulation of transcription by RNA polymerase II osteoblast development positive regulation of macrophage activation positive regulation of osteoblast differentiation positive regulation of transcription by RNA polymerase II regulation of cell cycle regulation o... |
detection of chemical stimulus involved in sensory perception of bitter taste epidermal growth factor receptor signaling pathway Fc receptor signaling pathway immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor receptor clustering | extracellular space; plasma membrane; receptor complex; recycling endosome membrane; secretory IgA immunoglobulin complex | epidermal growth factor receptor binding polymeric immunoglobulin binding polymeric immunoglobulin receptor activity | Rattus norvegicus | Cell membrane Disulfide bond Glycoprotein Immunoglobulin domain Membrane Phosphoprotein Reference proteome Repeat Secreted Signal Transmembrane Transmembrane helix | MRLSLFALLV | MRLSLFALLVTVFSGVSTQSPIFGPQDVSSIEGNSVSITCYYPDTSVNRHTRKYWCRQGANGYCATLISSNGYLSKEYSGRASLINFPENSTFVINIAHLTQEDTGSYKCGLGTTNRGLFFDVSLEVSQVPEFPNDTHVYTKDIGRTVTIECRFKEGNAHSKKSLCKKRGEACEVVIDSTEYVDPSYKDRAILFMKGTSRDIFYVNISHLIPSDAGLYVCQAGEGPSADKNNADLQVLEPEPELLYKDLRSSVTFECDLGREVANDAKYLCRKNKETCDVIINTLGKRDPAFEGRILLTPRDDNGRFSVLITGLRKEDAG... | detection of chemical stimulus involved in sensory perception of bitter taste epidermal growth factor receptor signaling pathway Fc receptor signaling pathway immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor receptor clustering extracellular space; plasma membrane; receptor ... |
leukotriene metabolic process proteolysis proteolysis involved in protein catabolic process response to cadmium ion | extracellular space | metallocarboxypeptidase activity zinc ion binding | Homo sapiens | 3D-structure Carboxypeptidase Direct protein sequencing Disulfide bond Hydrolase Metal-binding Metalloprotease Protease Reference proteome Secreted Signal Zinc Zymogen | MRGLLVLSVL | MRGLLVLSVLLGAVFGKEDFVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPAHPGSPIDVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRPAIWIDTGIHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGNIKAFISIHSYSQLLMYPYGYKT... | leukotriene metabolic process proteolysis proteolysis involved in protein catabolic process response to cadmium ion extracellular space metallocarboxypeptidase activity zinc ion binding Homo sapiens 3D-structure Carboxypeptidase Direct protein sequencing Disulfide bond Hydrolase Metal-binding Metalloprotease Protease R... |
proteolysis | cytoplasmic vesicle; extracellular space | carboxypeptidase activity metallocarboxypeptidase activity zinc ion binding | Homo sapiens | 3D-structure Carboxypeptidase Cytoplasmic vesicle Direct protein sequencing Disulfide bond Hydrolase Metal-binding Metalloprotease Protease Reference proteome Secreted Signal Zinc Zymogen | MLALLVLVTV | MLALLVLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTTQIDFWKPDSVTQIKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRVRATGHSYEKYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFHAREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIKAYLTIHSYSQMMIYPYSYAYKL... | proteolysis cytoplasmic vesicle; extracellular space carboxypeptidase activity metallocarboxypeptidase activity zinc ion binding Homo sapiens 3D-structure Carboxypeptidase Cytoplasmic vesicle Direct protein sequencing Disulfide bond Hydrolase Metal-binding Metalloprotease Protease Reference proteome Secreted Signal Zin... |
cardiac left ventricle morphogenesis enkephalin processing insulin processing negative regulation of branching morphogenesis of a nerve peptide catabolic process peptide hormone processing peptide hormone secretion peptide metabolic process protein localization to membrane protein localization to secretory granule prot... | dendrite; dense core granule; extracellular region; extracellular space; Golgi apparatus; neuronal cell body; perikaryon; secretory granule; secretory granule membrane; synaptic membrane; transport vesicle membrane | carboxypeptidase activity cell adhesion molecule binding cobalt ion binding metallocarboxypeptidase activity neurexin family protein binding protein domain specific binding zinc ion binding | Rattus norvegicus | Carboxypeptidase Cleavage on pair of basic residues Cytoplasmic vesicle Glycoprotein Hydrolase Membrane Metal-binding Metalloprotease Protease Reference proteome Secreted Signal Zinc Zymogen | MAGRGGRVLL | MAGRGGRVLLALCAALVAGGWLLAAEAQEPGAPAAGMRRRRRLQQEDGISFEYHRYPELREALVSVWLQCTAISRIYTVGRSFEGRELLVIELSDNPGVHEPGEPEFKYIGNMHGNEAVGRELLIFLAQYLCNEYQRGNETIVNLIHSTRIHIMPSLNPDGFEKAASQPGELKDWFVGRSNAQGIDLNRNFPDLDRIVYVNEKEGGPNNHLLKNLKKIVDQNSKLAPETKAVIHWIMDIPFVLSANLHGGDLVANYPYDETRSGTAHEYSSCPDDAIFQSLARAYSSFNPVMSDPNRPPCRKNDDDSSFVDGTTNGGAWY... | cardiac left ventricle morphogenesis enkephalin processing insulin processing negative regulation of branching morphogenesis of a nerve peptide catabolic process peptide hormone processing peptide hormone secretion peptide metabolic process protein localization to membrane protein localization to secretory granule prot... |
angiotensin maturation proteolysis | collagen-containing extracellular matrix; extracellular region; extracellular space; secretory granule; transport vesicle | metallocarboxypeptidase activity zinc ion binding | Homo sapiens | Carboxypeptidase Cytoplasmic vesicle Direct protein sequencing Disulfide bond Hydrolase Metal-binding Metalloprotease Protease Reference proteome Signal Zinc Zymogen | MRLILPVGLI | MRLILPVGLIATTLAIAPVRFDREKVFRVKPQDEKQADIIKDLAKTNELDFWYPGATHHVAANMMVDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVKEDIPGRHSYAKYNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKAIFTDCGIHAREWVSPAFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKNRSKNQNSKCIGTDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLNEIKVYITFHSYSQMLLFPYGYTSKL... | angiotensin maturation proteolysis collagen-containing extracellular matrix; extracellular region; extracellular space; secretory granule; transport vesicle metallocarboxypeptidase activity zinc ion binding Homo sapiens Carboxypeptidase Cytoplasmic vesicle Direct protein sequencing Disulfide bond Hydrolase Metal-bindin... |
brown fat cell differentiation cellular response to lithium ion cellular response to tumor necrosis factor cholesterol homeostasis fatty acid transport long-chain fatty acid transport negative regulation of DNA-templated transcription positive regulation of cold-induced thermogenesis positive regulation of inflammatory... | cytoplasm; cytosol; extracellular exosome; lipid droplet; nucleus | fatty acid binding hormone receptor binding long-chain fatty acid binding long-chain fatty acid transporter activity | Homo sapiens | 3D-structure Acetylation Cytoplasm Direct protein sequencing Lipid-binding Nucleus Phosphoprotein Reference proteome Transport | MCDAFVGTWK | MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVITIKSESTFKNTEISFILGQEFDEVTADDRKVKSTITLDGGVLVHVQKWDGKSTTIKRKREDDKLVVECVMKGVTSTRVYERA | brown fat cell differentiation cellular response to lithium ion cellular response to tumor necrosis factor cholesterol homeostasis fatty acid transport long-chain fatty acid transport negative regulation of DNA-templated transcription positive regulation of cold-induced thermogenesis positive regulation of inflammatory... |
behavioral response to ethanol blood vessel remodeling dopamine catabolic process fear response glucose homeostasis homoiothermy leukocyte mediated immunity leukocyte migration locomotory behavior maternal behavior memory norepinephrine biosynthetic process octopamine biosynthetic process positive regulation of cold-in... | centriolar satellite; chromaffin granule lumen; chromaffin granule membrane; endoplasmic reticulum; extracellular space; secretory granule lumen; secretory granule membrane; transport vesicle membrane | copper ion binding dopamine beta-monooxygenase activity L-ascorbic acid binding | Bos taurus | Catecholamine biosynthesis Copper Cytoplasmic vesicle Direct protein sequencing Disulfide bond Glycoprotein Membrane Metal-binding Monooxygenase Oxidoreductase Reference proteome Signal-anchor Transmembrane Transmembrane helix Vitamin C | MQVPSPSVRE | MQVPSPSVREAASMYGTAVAVFLVILVAALQGSAPAESPFPFHIPLDPEGTLELSWNISYAQETIYFQLLVRELKAGVLFGMSDRGELENADLVVLWTDRDGAYFGDAWSDQKGQVHLDSQQDYQLLRAQRTPEGLYLLFKRPFGTCDPNDYLIEDGTVHLVYGFLEEPLRSLESINTSGLHTGLQRVQLLKPSIPKPALPADTRTMEIRAPDVLIPGQQTTYWCYVTELPDGFPRHHIVMYEPIVTEGNEALVHHMEVFQCAAEFETIPHFSGPCDSKMKPQRLNFCRHVLAAWALGAKAFYYPEEAGLAFGGPGSSRF... | behavioral response to ethanol blood vessel remodeling dopamine catabolic process fear response glucose homeostasis homoiothermy leukocyte mediated immunity leukocyte migration locomotory behavior maternal behavior memory norepinephrine biosynthetic process octopamine biosynthetic process positive regulation of cold-in... |
angiogenesis glutamine biosynthetic process protein palmitoylation regulation of endothelial cell migration regulation of sprouting angiogenesis | cytoplasm; cytosol; endoplasmic reticulum; mitochondrion; plasma membrane | ATP binding glutamine synthetase activity metal ion binding protein-cysteine S-palmitoyltransferase activity | Bos taurus | 3D-structure Acetylation Angiogenesis ATP-binding Cell membrane Cytoplasm Endoplasmic reticulum Ligase Lipoprotein Magnesium Manganese Membrane Metal-binding Microsome Mitochondrion Nucleotide-binding Palmitate Phosphoprotein Reference proteome Transferase Ubl conjugation | MATSASSHLN | MATSASSHLNKGIKQVYMALPQGDKVQAMYIWIDGTGEGLRCKTRTLDSEPKCIEELPEWNFDGSSTFQSEGSNSDMYLVPAAMFRDPFRKDPNKLVFCEVFKYNRKPAETNLRHTCKRIMDMVSNQRPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADKAYGRDIVEAHYRACLYAGIKIGGTNAEVMPAQWEFQIGPCEGIDMGDHLWVARFILHRVCEDFGVIATFDPKPIPGNWNGAGCHTNFSTKAMREENGLKYIEEAIEKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRG... | angiogenesis glutamine biosynthetic process protein palmitoylation regulation of endothelial cell migration regulation of sprouting angiogenesis cytoplasm; cytosol; endoplasmic reticulum; mitochondrion; plasma membrane ATP binding glutamine synthetase activity metal ion binding protein-cysteine S-palmitoyltransferase a... |
angiogenesis cell population proliferation cellular response to starvation glutamate catabolic process glutamine biosynthetic process protein palmitoylation regulation of endothelial cell migration regulation of protein localization to nucleolus regulation of sprouting angiogenesis response to glucose ribosome biogenes... | cell body; cytoplasm; cytosol; endoplasmic reticulum; extracellular exosome; glial cell projection; mitochondrion; nucleus; plasma membrane | ATP binding glutamine synthetase activity identical protein binding metal ion binding protein-cysteine S-palmitoyltransferase activity | Homo sapiens | 3D-structure Acetylation Angiogenesis ATP-binding Cell membrane Cytoplasm Disease variant Endoplasmic reticulum Ligase Lipoprotein Magnesium Manganese Membrane Metal-binding Microsome Mitochondrion Nucleotide-binding Palmitate Phosphoprotein Reference proteome Transferase Ubl conjugation | MTTSASSHLN | MTTSASSHLNKGIKQVYMSLPQGEKVQAMYIWIDGTGEGLRCKTRTLDSEPKCVEELPEWNFDGSSTLQSEGSNSDMYLVPAAMFRDPFRKDPNKLVLCEVFKYNRRPAETNLRHTCKRIMDMVSNQHPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADRAYGRDIVEAHYRACLYAGVKIAGTNAEVMPAQWEFQIGPCEGISMGDHLWVARFILHRVCEDFGVIATFDPKPIPGNWNGAGCHTNFSTKAMREENGLKYIEEAIEKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRS... | angiogenesis cell population proliferation cellular response to starvation glutamate catabolic process glutamine biosynthetic process protein palmitoylation regulation of endothelial cell migration regulation of protein localization to nucleolus regulation of sprouting angiogenesis response to glucose ribosome biogenes... |
ammonia assimilation cycle angiogenesis cell population proliferation cellular response to starvation glutamate metabolic process glutamine biosynthetic process positive regulation of epithelial cell proliferation positive regulation of insulin secretion positive regulation of synaptic transmission, glutamatergic prote... | axon terminus; cell body; cell projection; cytoplasm; cytosol; endoplasmic reticulum; glial cell projection; mitochondrion; myelin sheath; perikaryon; plasma membrane; protein-containing complex | ATP binding dynein light chain binding glutamate binding glutamine synthetase activity identical protein binding magnesium ion binding manganese ion binding nickel cation binding protein-cysteine S-palmitoyltransferase activity | Mus musculus | Acetylation Angiogenesis ATP-binding Cell membrane Cytoplasm Direct protein sequencing Endoplasmic reticulum Ligase Lipoprotein Magnesium Manganese Membrane Metal-binding Microsome Mitochondrion Nucleotide-binding Palmitate Phosphoprotein Reference proteome Transferase Ubl conjugation | MATSASSHLN | MATSASSHLNKGIKQMYMSLPQGEKVQAMYIWVDGTGEGLRCKTRTLDCEPKCVEELPEWNFDGSSTFQSEGSNSDMYLHPVAMFRDPFRKDPNKLVLCEVFKYNRKPAETNLRHICKRIMDMVSNQHPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADKAYGRDIVEAHYRACLYAGVKITGTNAEVMPAQWEFQIGPCEGIRMGDHLWIARFILHRVCEDFGVIATFDPKPIPGNWNGAGCHTNFSTKAMREENGLKCIEEAIDKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRG... | ammonia assimilation cycle angiogenesis cell population proliferation cellular response to starvation glutamate metabolic process glutamine biosynthetic process positive regulation of epithelial cell proliferation positive regulation of insulin secretion positive regulation of synaptic transmission, glutamatergic prote... |
box C/D snoRNP assembly cellular response to heat proteasome assembly protein folding protein stabilization response to oxygen levels telomere maintenance | cytoplasm; cytosol; mitochondrion; perinuclear region of cytoplasm; plasma membrane; protein-containing complex | ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone unfolded protein binding | Saccharomyces cerevisiae | 3D-structure ATP-binding Chaperone Coiled coil Cytoplasm Direct protein sequencing Mitochondrion Nucleotide-binding Phosphoprotein Reference proteome Repeat Stress response | MAGETFEFQA | MAGETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQALSDPKQLETEPDLFIRITPKPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVGFYSLFLVADRVQVISKNNEDEQYIWESNAGGSFTVTLDEVNERIGRGTVLRLFLKDDQLEYLEEKRIKEVIKRHSEFVAYPIQLLVTKEVEKEVPIPEEEKKDEEKKDEDDKKPKLEEVDEEEEEKKPKTKKVKEEVQELEELNKTKPLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIP... | box C/D snoRNP assembly cellular response to heat proteasome assembly protein folding protein stabilization response to oxygen levels telomere maintenance cytoplasm; cytosol; mitochondrion; perinuclear region of cytoplasm; plasma membrane; protein-containing complex ATP binding ATP hydrolysis activity ATP-dependent pro... |
C21-steroid hormone biosynthetic process carbohydrate metabolic process cellular hyperosmotic salinity response daunorubicin metabolic process doxorubicin metabolic process epithelial cell maturation fructose biosynthetic process L-ascorbic acid biosynthetic process metanephric collecting duct development negative regu... | cytosol; extracellular exosome; extracellular space; nucleoplasm | alditol:NADP+ 1-oxidoreductase activity allyl-alcohol dehydrogenase activity electron transfer activity glyceraldehyde oxidoreductase activity glycerol dehydrogenase activity L-glucuronate reductase activity NADP-retinol dehydrogenase activity prostaglandin H2 endoperoxidase reductase activity retinal dehydrogenase ac... | Homo sapiens | 3D-structure Acetylation Cytoplasm Direct protein sequencing Lipid metabolism NADP Oxidoreductase Phosphoprotein Reference proteome | MASRLLLNNG | MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSCTSHKDYPFHEEF | C21-steroid hormone biosynthetic process carbohydrate metabolic process cellular hyperosmotic salinity response daunorubicin metabolic process doxorubicin metabolic process epithelial cell maturation fructose biosynthetic process L-ascorbic acid biosynthetic process metanephric collecting duct development negative regu... |
retinoid metabolic process | cytoplasm | alditol:NADP+ 1-oxidoreductase activity allyl-alcohol dehydrogenase activity glycerol dehydrogenase activity NADP-retinol dehydrogenase activity prostaglandin H2 endoperoxidase reductase activity retinal dehydrogenase activity | Oryctolagus cuniculus | Acetylation Cytoplasm Lipid metabolism NADP Oxidoreductase Reference proteome | MATHLVLYNG | MATHLVLYNGAKMPILGLGTWKSPPGQVTEAVKTAIDLGYRHIDCAHVYQNENEVGVALQEKLKEQVVKREELFIVSKLWCTSHDKSLVKGACQKTLNDLKLDYLDLYLIHWPTGFKHGSEYFPLDAAGNVIPSDTDFLDTWEAMEGLVDEGLVKSIGVSNFNHLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIQYCHSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIADKHKKTTAQVLIRFPMQRNLVVIPKSVTPARIAENFQVFDFELSSEDMTTLLSYNRNWRVCALVSCASHKDYPFHAEF | retinoid metabolic process cytoplasm alditol:NADP+ 1-oxidoreductase activity allyl-alcohol dehydrogenase activity glycerol dehydrogenase activity NADP-retinol dehydrogenase activity prostaglandin H2 endoperoxidase reductase activity retinal dehydrogenase activity Oryctolagus cuniculus Acetylation Cytoplasm Lipid metab... |
biphenyl metabolic process | endoplasmic reticulum membrane | aromatase activity heme binding heterocyclic compound binding iron ion binding monooxygenase activity | Rattus norvegicus | Direct protein sequencing Endoplasmic reticulum Heme Iron Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Reference proteome | MVLNFLSPSL | MVLNFLSPSLSRLGLWASVVILMVIVLKLFSLLLRRQKLARAMDSFPGPPTHWLFGHALEIQKLGSLDKVVSWAQQFPHAHPLWFGQFVGFLNIYEPDYAKAVYSRGDPKAADVYDFFLQWIGKGLLVLDGPKWFQHRKLLTPGFHYDVLKPYVAIFAESTRMMLDKWEKKASENKSFDIFCDVGHMALDTLMKCTFGKGDSGLGHRDNSYYLAVSDLTLLMQQRIDSFQYHNDFIYWLTPHGRRFLRACKIAHDHTDEVIRQRKAALQDEKERKKIQQRRHLDFLDILLGVRDESGIKLSDAELRAEVDTFMFEGHDTT... | biphenyl metabolic process endoplasmic reticulum membrane aromatase activity heme binding heterocyclic compound binding iron ion binding monooxygenase activity Rattus norvegicus Direct protein sequencing Endoplasmic reticulum Heme Iron Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Reference proteome MVL... |
angiogenesis cell differentiation peptide catabolic process proteolysis | cytoplasm; endoplasmic reticulum-Golgi intermediate compartment; external side of plasma membrane; extracellular exosome; extracellular space; lysosomal membrane; plasma membrane; secretory granule membrane | aminopeptidase activity metalloaminopeptidase activity metallopeptidase activity peptide binding signaling receptor activity virus receptor activity zinc ion binding | Homo sapiens | 3D-structure Aminopeptidase Angiogenesis Cell membrane Developmental protein Differentiation Direct protein sequencing Disulfide bond Glycoprotein Host cell receptor for virus entry Host-virus interaction Hydrolase Membrane Metal-binding Metalloprotease Protease Receptor Reference proteome Signal-anchor Sulfation Trans... | MAKGFYISKS | MAKGFYISKSLGILGILLGVAAVCTIIALSVVYSQEKNKNANSSPVASTTPSASATTNPASATTLDQSKAWNRYRLPNTLKPDSYRVTLRPYLTPNDRGLYVFKGSSTVRFTCKEATDVIIIHSKKLNYTLSQGHRVVLRGVGGSQPPDIDKTELVEPTEYLVVHLKGSLVKDSQYEMDSEFEGELADDLAGFYRSEYMEGNVRKVVATTQMQAADARKSFPCFDEPAMKAEFNITLIHPKDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFDYVEKQASNGVLIRIWARPSAIAAGHGDYALNV... | angiogenesis cell differentiation peptide catabolic process proteolysis cytoplasm; endoplasmic reticulum-Golgi intermediate compartment; external side of plasma membrane; extracellular exosome; extracellular space; lysosomal membrane; plasma membrane; secretory granule membrane aminopeptidase activity metalloaminopepti... |
angiogenesis cell differentiation peptide catabolic process proteolysis | cytoplasm; plasma membrane | metalloaminopeptidase activity peptide binding virus receptor activity zinc ion binding | Sus scrofa | 3D-structure Aminopeptidase Angiogenesis Cell membrane Developmental protein Differentiation Direct protein sequencing Disulfide bond Glycoprotein Host cell receptor for virus entry Host-virus interaction Hydrolase Membrane Metal-binding Metalloprotease Protease Receptor Reference proteome Signal-anchor Sulfation Trans... | MAKGFYISKA | MAKGFYISKALGILGILLGVAAVATIIALSVVYAQEKNKNAEHVPQAPTSPTITTTAAITLDQSKPWNRYRLPTTLLPDSYNVTLRPYLTPNADGLYIFKGKSIVRLLCQEPTDVIIIHSKKLNYTTQGHMVVLRGVGDSQVPEIDRTELVELTEYLVVHLKGSLQPGHMYEMESEFQGELADDLAGFYRSEYMEGNVKKVLATTQMQSTDARKSFPCFDEPAMKATFNITLIHPNNLTALSNMPPKGSSTPLAEDPNWSVTEFETTPVMSTYLLAYIVSEFQSVNETAQNGVLIRIWARPNAIAEGHGMYALNVTGPIL... | angiogenesis cell differentiation peptide catabolic process proteolysis cytoplasm; plasma membrane metalloaminopeptidase activity peptide binding virus receptor activity zinc ion binding Sus scrofa 3D-structure Aminopeptidase Angiogenesis Cell membrane Developmental protein Differentiation Direct protein sequencing Dis... |
coumarin metabolic process epoxygenase P450 pathway xenobiotic metabolic process | cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle | arachidonic acid epoxygenase activity aromatase activity heme binding iron ion binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen steroid hydroxylase activity | Rattus norvegicus | Direct protein sequencing Endoplasmic reticulum Heme Iron Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Reference proteome | MLDTGLLLVV | MLDTGLLLVVILASLSVMFLVSLWQQKIRERLPPGPTPLPFIGNYLQLNMKDVYSSITQLSERYGPVFTIHLGPRRIVVLYGYDAVKEALVDQAEEFSGRGELPTFNILFKGYGFSLSNVEQAKRIRRFTIATLRDFGVGKRDVQECILEEAGYLIKTLQGTCGAPIDPSIYLSKTVSNVINSIVFGNRFDYEDKEFLSLLEMIDEMNIFAASATGQLYDMFHSVMKYLPGPQQQIIKVTQKLEDFMIEKVRQNHSTLDPNSPRNFIDSFLIRMQEEKYVNSEFHMNNLVMSSLGLLFAGTGSVSSTLYHGFLLLMKHPD... | coumarin metabolic process epoxygenase P450 pathway xenobiotic metabolic process cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle arachidonic acid epoxygenase activity aromatase activity heme binding iron ion binding oxidoreductase activity, acting on paired donors, with incorporation... |
aldosterone biosynthetic process cellular response to peptide hormone stimulus cholesterol metabolic process cortisol metabolic process glucocorticoid biosynthetic process | mitochondrial inner membrane | corticosterone 18-monooxygenase activity heme binding iron ion binding steroid 11-beta-monooxygenase activity | Bos taurus | Direct protein sequencing Heme Iron Lipid metabolism Membrane Metal-binding Mitochondrion Mitochondrion inner membrane Monooxygenase Oxidoreductase Reference proteome Steroid metabolism Steroidogenesis Transit peptide | MALWAKARVR | MALWAKARVRMAGPWLSLHEARLLGTRGAAAPKAVLPFEAMPRCPGNKWMRMLQIWKEQSSENMHLDMHQTFQELGPIFRYDVGGRHMVFVMLPEDVERLQQADSHHPQRMILEPWLAYRQARGHKCGVFLLNGPQWRLDRLRLNPDVLSLPALQKYTPLVDGVARDFSQTLKARVLQNARGSLTLDIAPSVFRYTIEASTLVLYGERLGLLTQQPNPDSLNFIHALEAMLKSTVQLMFVPRRLSRWMSTNMWREHFEAWDYIFQYANRAIQRIYQELALGHPWHYSGIVAELLMRADMTLDTIKANTIDLTAGSVDTTA... | aldosterone biosynthetic process cellular response to peptide hormone stimulus cholesterol metabolic process cortisol metabolic process glucocorticoid biosynthetic process mitochondrial inner membrane corticosterone 18-monooxygenase activity heme binding iron ion binding steroid 11-beta-monooxygenase activity Bos tauru... |
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules homophilic cell adhesion via plasma membrane adhesion molecules positive regulation of natural killer cell mediated cytotoxicity positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target susceptibility ... | adherens junction; cell surface; cytoplasm; extracellular space; focal adhesion; membrane; plasma membrane | cell adhesion molecule binding signaling receptor activity virus receptor activity | Homo sapiens | 3D-structure Alternative splicing Cell adhesion Cell membrane Disulfide bond Glycoprotein Host cell receptor for virus entry Host-virus interaction Immunoglobulin domain Membrane Phosphoprotein Receptor Reference proteome Repeat Secreted Signal Transmembrane Transmembrane helix | MARAMAAAWP | MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGA... | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules homophilic cell adhesion via plasma membrane adhesion molecules positive regulation of natural killer cell mediated cytotoxicity positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target susceptibility ... |
actin filament organization bone resorption cell projection assembly chemotaxis erythrocyte enucleation G protein-coupled receptor signaling pathway lymphocyte aggregation mast cell proliferation positive regulation of lamellipodium assembly positive regulation of mast cell proliferation positive regulation of neutroph... | cytosol; endoplasmic reticulum membrane; extracellular exosome; focal adhesion; lamellipodium; mitochondrial outer membrane; NADPH oxidase complex; nuclear envelope; phagocytic vesicle membrane; plasma membrane | GTP binding GTPase activity protein kinase regulator activity | Homo sapiens | 3D-structure Acetylation ADP-ribosylation Cytoplasm Direct protein sequencing Disease variant Glycoprotein GTP-binding Lipoprotein Methylation Nucleotide-binding Prenylation Reference proteome | MQAIKCVVVG | MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTRQQKRACSLL | actin filament organization bone resorption cell projection assembly chemotaxis erythrocyte enucleation G protein-coupled receptor signaling pathway lymphocyte aggregation mast cell proliferation positive regulation of lamellipodium assembly positive regulation of mast cell proliferation positive regulation of neutroph... |
collagen catabolic process proteolysis | extracellular region | metal ion binding metalloendopeptidase activity toxin activity | Crotalus atrox | 3D-structure Calcium Collagen degradation Direct protein sequencing Disulfide bond Hemorrhagic toxin Hemostasis impairing toxin Hydrolase Metal-binding Metalloprotease Protease Pyrrolidone carboxylic acid Secreted Signal Toxin Zinc Zymogen | MIEVLLVTIC | MIEVLLVTICLAVFPYQGSSIILESGNVNDYEVVYPRKVTALPKGAVQPKYEDAMQYELKVNGEPVVLHLEKNKELFSKDYSETHYSPDGRKITTNPSVEDHCYYRGRIENDADSTASISACNGLKGHFKLQGEMYLIEPLELSDSEAHAVFKLENVEKEDEAPKMCGVTQNWESYEPIKKASDLNLNPDQQNLPQRYIELVVVADHRVFMKYNSDLNTIRTRVHEIVNFINGFYRSLNIHVSLTDLEIWSNEDQINIQSASSDTLNAFAEWRETDLLNRKSHDNAQLLTAIELDEETLGLAPLGTMCDPKLSIGIVQDH... | collagen catabolic process proteolysis extracellular region metal ion binding metalloendopeptidase activity toxin activity Crotalus atrox 3D-structure Calcium Collagen degradation Direct protein sequencing Disulfide bond Hemorrhagic toxin Hemostasis impairing toxin Hydrolase Metal-binding Metalloprotease Protease Pyrro... |
bradykinin catabolic process peptide metabolic process protein catabolic process protein processing response to glucocorticoid | extracellular region; extracellular space | metallocarboxypeptidase activity zinc ion binding | Homo sapiens | 3D-structure Carboxypeptidase Direct protein sequencing Disease variant Disulfide bond Glycoprotein Hydrolase Metal-binding Metalloprotease Protease Reference proteome Secreted Signal Zinc | MSDLLSVFLH | MSDLLSVFLHLLLLFKLVAPVTFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQGPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPNHHLPLPDNWKSQVEPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTASTPTPDDKLFQKLAKVYSYAHGWMFQGWNCGDYFPDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPPEEEL... | bradykinin catabolic process peptide metabolic process protein catabolic process protein processing response to glucocorticoid extracellular region; extracellular space metallocarboxypeptidase activity zinc ion binding Homo sapiens 3D-structure Carboxypeptidase Direct protein sequencing Disease variant Disulfide bond G... |
G1/S transition of mitotic cell cycle nuclear-transcribed mRNA catabolic process, nonsense-mediated decay protein methylation regulation of translational termination translation translational termination | cytoplasm; cytosol; cytosolic ribosome; translation release factor complex | GTP binding GTPase activity RNA binding translation release factor activity | Homo sapiens | 3D-structure Alternative splicing GTP-binding Hydrolase Nonsense-mediated mRNA decay Nucleotide-binding Protein biosynthesis Reference proteome | MELSEPIVEN | MELSEPIVENGETEMSPEESWEHKEEISEAEPGGGSLGDGRPPEESAHEMMEEEEEIPKPKSVVAPPGAPKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLKEQSDFCPWYIGLPFIPYLDNLPNFNRSVDGPIRLPIVDKYKDMGTVVLGK... | G1/S transition of mitotic cell cycle nuclear-transcribed mRNA catabolic process, nonsense-mediated decay protein methylation regulation of translational termination translation translational termination cytoplasm; cytosol; cytosolic ribosome; translation release factor complex GTP binding GTPase activity RNA binding t... |
cell cycle cellular response to estradiol stimulus cellular response to growth factor stimulus cellular response to lithium ion cellular response to tumor necrosis factor muscle cell fate commitment negative regulation of cell population proliferation ossification positive regulation of muscle atrophy positive regulati... | chromatin; nucleoplasm; nucleus; protein-DNA complex; transcription regulator complex | chromatin DNA binding DNA-binding transcription activator activity DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific E-box binding protein dimerization activity RNA polymerase II cis-re... | Homo sapiens | Activator Cell cycle Developmental protein Differentiation DNA-binding Myogenesis Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MELYETSPYF | MELYETSPYFYQEPRFYDGENYLPVHLQGFEPPGYERTELTLSPEAPGPLEDKGLGTPEHCPGQCLPWACKVCKRKSVSVDRRRAATLREKRRLKKVNEAFEALKRSTLLNPNQRLPKVEILRSAIQYIERLQALLSSLNQEERDLRYRGGGGPQPGVPSECSSHSASCSPEWGSALEFSANPGDHLLTADPTDAHNLHSLTSIVDSITVEDVSVAFPDETMPN | cell cycle cellular response to estradiol stimulus cellular response to growth factor stimulus cellular response to lithium ion cellular response to tumor necrosis factor muscle cell fate commitment negative regulation of cell population proliferation ossification positive regulation of muscle atrophy positive regulati... |
lysyl-tRNA aminoacylation | cytoplasm; cytosol | ATP binding lysine-tRNA ligase activity mRNA binding tRNA binding | Saccharomyces cerevisiae | 3D-structure Acetylation Aminoacyl-tRNA synthetase ATP-binding Cytoplasm Direct protein sequencing Isopeptide bond Ligase Nucleotide-binding Phosphoprotein Protein biosynthesis Reference proteome Ubl conjugation | MSQQDNVKAA | MSQQDNVKAAAEGVANLHLDEATGEMVSKSELKKRIKQRQVEAKKAAKKAAAQPKPASKKKTDLFADLDPSQYFETRSRQIQELRKTHEPNPYPHKFHVSISNPEFLAKYAHLKKGETLPEEKVSIAGRIHAKRESGSKLKFYVLHGDGVEVQLMSQLQDYCDPDSYEKDHDLLKRGDIVGVEGYVGRTQPKKGGEGEVSVFVSRVQLLTPCLHMLPADHFGFKDQETRYRKRYLDLIMNKDARNRFITRSEIIRYIRRFLDQRKFIEVETPMMNVIAGGATAKPFITHHNDLDMDMYMRIAPELFLKQLVVGGLDRVYE... | lysyl-tRNA aminoacylation cytoplasm; cytosol ATP binding lysine-tRNA ligase activity mRNA binding tRNA binding Saccharomyces cerevisiae 3D-structure Acetylation Aminoacyl-tRNA synthetase ATP-binding Cytoplasm Direct protein sequencing Isopeptide bond Ligase Nucleotide-binding Phosphoprotein Protein biosynthesis Refere... |
disruption by virus of host JAK-STAT cascade via inhibition of STAT1 activity disruption by virus of host JAK-STAT cascade via inhibition of STAT2 activity microtubule-dependent intracellular transport of viral material towards nucleus suppression by virus of host toll-like receptor signaling pathway suppression by vir... | host cell cytoplasm; host cell nucleus; virion component | RNA-dependent RNA polymerase activity | Rabies virus | 3D-structure Alternative initiation Chaperone Cytoplasmic inwards viral transport Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Inhibition of host STAT1 by virus Inhibition of host STAT2 by virus Inhibition ... | MSKIFVNPSA | MSKIFVNPSAIRAGLADLEMAEETVDLINRNIEDNDAHLQGEPIEVDNLPEDMKRLHLDDEKSSNLGEMVRVGEGKYREDFQMDEGEDPNLLFQSYLDNVGVQIVRQMRSGERFLKIWSQTVEEIVSYVTVNFPNPPRRSSEDKSTQTTGRELKKETTSAFSQRESQPSKARMVAQVAPGPPALEWSATNEEDDLSVEAEIAHQIAESFSKKYKFPSRSSGIFLYNFEQLKMNLDDIVKEAKNVPGVTRLAHDGSKIPLRCVLGWVALANSKKFQLLVEADKLSKIMQDDLNRYTSC | disruption by virus of host JAK-STAT cascade via inhibition of STAT1 activity disruption by virus of host JAK-STAT cascade via inhibition of STAT2 activity microtubule-dependent intracellular transport of viral material towards nucleus suppression by virus of host toll-like receptor signaling pathway suppression by vir... |
hydrogen peroxide catabolic process response to hydrogen peroxide response to reactive oxygen species | cytoplasm; mitochondrial matrix; mitochondrion; peroxisomal matrix; peroxisome | catalase activity heme binding metal ion binding | Saccharomyces cerevisiae | 3D-structure Acetylation Heme Hydrogen peroxide Iron Metal-binding Oxidoreductase Peroxidase Peroxisome Reference proteome | MSKLGQEKNE | MSKLGQEKNEVNYSDVREDRVVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAFGYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGNLDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTTPENQVAIHQVMILFSDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPDYCQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIVLNENPL... | hydrogen peroxide catabolic process response to hydrogen peroxide response to reactive oxygen species cytoplasm; mitochondrial matrix; mitochondrion; peroxisomal matrix; peroxisome catalase activity heme binding metal ion binding Saccharomyces cerevisiae 3D-structure Acetylation Heme Hydrogen peroxide Iron Metal-bindi... |
cell-cell junction organization detection of hypoxia face morphogenesis negative regulation of cell population proliferation negative regulation of macrophage cytokine production positive regulation of cell division positive regulation of cell population proliferation positive regulation of collagen biosynthetic proces... | extracellular matrix; extracellular space | cytokine activity growth factor activity identical protein binding transforming growth factor beta binding type I transforming growth factor beta receptor binding type II transforming growth factor beta receptor binding type III transforming growth factor beta receptor binding | Sus scrofa | Cleavage on pair of basic residues Disulfide bond Extracellular matrix Glycoprotein Growth factor Mitogen Reference proteome Secreted Signal | MHLQRALVVL | MHLQRALVVLALLNFATVSLSMSTCTTLDFDHIKRKRVEAIRGQILSKLRLTSPPDPSMLANIPTQVLDLYNSTRELLEEVHGERGDDCTQENTESEYYAKEIYKFDMIQGLEEHNDLAVCPKGITSKIFRFNVSSVEKNETNLFRAEFRVLRMPNPSSKRSEQRIELFQILQPDEHIAKQRYIDGKNLPTRGAAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENIQEVMEIKFKGVDSEDDPGRGDLGRLKKKKEHSPHLILMMIPPDRLDNPGLGAQRKKRALDTNYCFRNLEENCCVRPLYID... | cell-cell junction organization detection of hypoxia face morphogenesis negative regulation of cell population proliferation negative regulation of macrophage cytokine production positive regulation of cell division positive regulation of cell population proliferation positive regulation of collagen biosynthetic proces... |
positive regulation of DNA-templated transcription | nucleus | nuclear receptor activity nuclear retinoid X receptor binding nuclear thyroid hormone receptor binding protein heterodimerization activity protein homodimerization activity sequence-specific DNA binding thyroid hormone binding zinc ion binding | Xenopus laevis | DNA-binding Metal-binding Nucleus Receptor Reference proteome Transcription Transcription regulation Zinc Zinc-finger | MDQNLSGLDC | MDQNLSGLDCLSEPDEKRWPDGKRKRKNSQCMGKSGMSGDSLVSLPSAGYIPSYLDKDEPCVVCSDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYDGCCIIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSKRVAKRKLIEENRQRRRKEEMIKTLQQRPEPSSEEWELIRIVTEAHRSTNAQGSHWKQRRKFLPEDIGQSPMASMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFSELTCEDQIILLKGCCMEIMSLRAAVRYDPDSETLTLSGEMAVKREQLKNGGLGVVSDAIFDLGRSLAAFNLD... | positive regulation of DNA-templated transcription nucleus nuclear receptor activity nuclear retinoid X receptor binding nuclear thyroid hormone receptor binding protein heterodimerization activity protein homodimerization activity sequence-specific DNA binding thyroid hormone binding zinc ion binding Xenopus laevis DN... |
defense response to fungus killing of cells of another organism | extracellular region | sodium channel inhibitor activity toxin activity | Tityus serrulatus | 3D-structure Amidation Antimicrobial Direct protein sequencing Disulfide bond Fungicide Ion channel impairing toxin Neurotoxin Secreted Signal Toxin Voltage-gated sodium channel impairing toxin | MKGMILFISC | MKGMILFISCLLLIGIVVECKEGYLMDHEGCKLSCFIRPSGYCGRECGIKKGSSGYCAWPACYCYGLPNWVKVWDRATNKCGKK | defense response to fungus killing of cells of another organism extracellular region sodium channel inhibitor activity toxin activity Tityus serrulatus 3D-structure Amidation Antimicrobial Direct protein sequencing Disulfide bond Fungicide Ion channel impairing toxin Neurotoxin Secreted Signal Toxin Voltage-gated sodiu... |
B cell differentiation B cell proliferation immunoglobulin mediated immune response positive regulation of cell growth positive regulation of interleukin-5 production regulation of peptidyl-tyrosine phosphorylation regulation of receptor signaling pathway via JAK-STAT | extracellular space | cytokine activity growth factor activity interleukin-9 receptor binding | Mus musculus | 3D-structure Cytokine Direct protein sequencing Glycoprotein Growth factor Pyrrolidone carboxylic acid Reference proteome Secreted Signal | MLVTYILASV | MLVTYILASVLLFSSVLGQRCSTTWGIRDTNYLIENLKDDPPSKCSCSGNVTSCLCLSVPTDDCTTPCYREGLLQLTNATQKSRLLPVFHRVKRIVEVLKNITCPSFSCEKPCNQTMAGNTLSFLKSLLGTFQKTEMQRQKSRP | B cell differentiation B cell proliferation immunoglobulin mediated immune response positive regulation of cell growth positive regulation of interleukin-5 production regulation of peptidyl-tyrosine phosphorylation regulation of receptor signaling pathway via JAK-STAT extracellular space cytokine activity growth factor... |
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