Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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B cell differentiation B cell proliferation immunoglobulin mediated immune response inflammatory response positive regulation of cell growth positive regulation of cell population proliferation positive regulation of interleukin-5 production regulation of peptidyl-tyrosine phosphorylation regulation of receptor signaling pathway via JAK-STAT | extracellular region; extracellular space | cytokine activity growth factor activity interleukin-9 receptor binding | Homo sapiens | 3D-structure Cytokine Glycoprotein Growth factor Pyrrolidone carboxylic acid Reference proteome Secreted Signal | MLLAMVLTSA | MLLAMVLTSALLLCSVAGQGCPTLAGILDINFLINKMQEDPASKCHCSANVTSCLCLGIPSDNCTRPCFSERLSQMTNTTMQTRYPLIFSRVKKSVEVLKNNKCPYFSCEQPCNQTTAGNALTFLKSLLEIFQKEKMRGMRGKI | B cell differentiation B cell proliferation immunoglobulin mediated immune response inflammatory response positive regulation of cell growth positive regulation of cell population proliferation positive regulation of interleukin-5 production regulation of peptidyl-tyrosine phosphorylation regulation of receptor signaling pathway via JAK-STAT extracellular region; extracellular space cytokine activity growth factor activity interleukin-9 receptor binding Homo sapiens 3D-structure Cytokine Glycoprotein Growth factor Pyrrolidone carboxylic acid Reference proteome Secreted Signal MLLAMVLTSA MLLAMVLTSALLLCSVAGQGCPTLAGILDINFLINKMQEDPASKCHCSANVTSCLCLGIPSDNCTRPCFSERLSQMTNTTMQTRYPLIFSRVKKSVEVLKNNKCPYFSCEQPCNQTTAGNALTFLKSLLEIFQKEKMRGMRGKI |
protein folding protein stabilization | cell surface; cortical granule; cytolytic granule; cytosol; extracellular region; sarcoplasmic reticulum; sarcoplasmic reticulum lumen | calcium ion binding carbohydrate binding unfolded protein binding | Oryctolagus cuniculus | Acetylation Calcium Chaperone Cytoplasm Cytoplasmic vesicle Direct protein sequencing Disulfide bond Endoplasmic reticulum Extracellular matrix Hydroxylation Lectin Lysosome Metal-binding Reference proteome Repeat Sarcoplasmic reticulum Secreted Signal Zinc | MLLPVPLLLG | MLLPVPLLLGLLGLAAAEPVVYFKEQFLDGDGWTERWIESKHKSDFGKFVLSSGKFYGDQEKDKGLQTSQDARFYALSARFEPFSNKGQPLVVQFTVKHEQNIDCGGGYVKLFPAGLDQKDMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDASKPEDWDERAKIDDPTDSKPEDWDKPEHIPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYSPDANIYAYDSFAVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKTAEKQMKDKQDEEQRLKEEEEEKKRKEEEEAEEDEEDKDDKEDEDEDEEDKDEEEEEAAAGQAKDEL | protein folding protein stabilization cell surface; cortical granule; cytolytic granule; cytosol; extracellular region; sarcoplasmic reticulum; sarcoplasmic reticulum lumen calcium ion binding carbohydrate binding unfolded protein binding Oryctolagus cuniculus Acetylation Calcium Chaperone Cytoplasm Cytoplasmic vesicle Direct protein sequencing Disulfide bond Endoplasmic reticulum Extracellular matrix Hydroxylation Lectin Lysosome Metal-binding Reference proteome Repeat Sarcoplasmic reticulum Secreted Signal Zinc MLLPVPLLLG MLLPVPLLLGLLGLAAAEPVVYFKEQFLDGDGWTERWIESKHKSDFGKFVLSSGKFYGDQEKDKGLQTSQDARFYALSARFEPFSNKGQPLVVQFTVKHEQNIDCGGGYVKLFPAGLDQKDMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDASKPEDWDERAKIDDPTDSKPEDWDKPEHIPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYSPDANIYAYDSFAVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKTAEKQMKDKQDEEQRLKEEEEEKKRKEEEEAEEDEEDKDDKEDEDEDEEDKDEEEEEAAAGQAKDEL |
canonical glycolysis gluconeogenesis glycolytic process Notch signaling pathway response to mercury ion spermatogenesis striated muscle contraction | cytosol; extracellular exosome; nucleus | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity bisphosphoglycerate mutase activity hydrolase activity identical protein binding phosphoglycerate mutase activity | Homo sapiens | Disease variant Glycogen storage disease Glycolysis Hydrolase Isomerase Phosphoprotein Reference proteome | MATHRLVMVR | MATHRLVMVRHGESTWNQENRFCGWFDAELSEKGTEEAKRGAKAIKDAKMEFDICYTSVLKRAIRTLWAILDGTDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEEQVKIWRRSFDIPPPPMDEKHPYYNSISKERRYAGLKPGELPTCESLKDTIARALPFWNEEIVPQIKAGKRVLIAAHGNSLRGIVKHLEGMSDQAIMELNLPTGIPIVYELNKELKPTKPMQFLGDEETVRKAMEAVAAQGKAK | canonical glycolysis gluconeogenesis glycolytic process Notch signaling pathway response to mercury ion spermatogenesis striated muscle contraction cytosol; extracellular exosome; nucleus 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity bisphosphoglycerate mutase activity hydrolase activity identical protein binding phosphoglycerate mutase activity Homo sapiens Disease variant Glycogen storage disease Glycolysis Hydrolase Isomerase Phosphoprotein Reference proteome MATHRLVMVR MATHRLVMVRHGESTWNQENRFCGWFDAELSEKGTEEAKRGAKAIKDAKMEFDICYTSVLKRAIRTLWAILDGTDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEEQVKIWRRSFDIPPPPMDEKHPYYNSISKERRYAGLKPGELPTCESLKDTIARALPFWNEEIVPQIKAGKRVLIAAHGNSLRGIVKHLEGMSDQAIMELNLPTGIPIVYELNKELKPTKPMQFLGDEETVRKAMEAVAAQGKAK |
astrocyte activation cellular response to virus cytokine-mediated signaling pathway microglial cell activation negative regulation of amyloid-beta clearance positive regulation of amyloid-beta formation positive regulation of gene expression positive regulation of tumor necrosis factor production response to virus signal transduction type II interferon-mediated signaling pathway type III interferon-mediated signaling pathway | membrane; plasma membrane | cytokine binding cytokine receptor activity type II interferon receptor activity | Homo sapiens | 3D-structure Alternative splicing Cell membrane Direct protein sequencing Disease variant Disulfide bond Glycoprotein Immunoglobulin domain Membrane Phosphoprotein Receptor Reference proteome Signal Transmembrane Transmembrane helix Ubl conjugation | MALLFLLPLV | MALLFLLPLVMQGVSRAEMGTADLGPSSVPTPTNVTIESYNMNPIVYWEYQIMPQVPVFTVEVKNYGVKNSEWIDACINISHHYCNISDHVGDPSNSLWVRVKARVGQKESAYAKSEEFAVCRDGKIGPPKLDIRKEEKQIMIDIFHPSVFVNGDEQEVDYDPETTCYIRVYNVYVRMNGSEIQYKILTQKEDDCDEIQCQLAIPVSSLNSQYCVSAEGVLHVWGVTTEKSKEVCITIFNSSIKGSLWIPVVAALLLFLVLSLVFICFYIKKINPLKEKSIILPKSLISVVRSATLETKPESKYVSLITSYQPFSLEKEVVCEEPLSPATVPGMHTEDNPGKVEHTEELSSITEVVTTEENIPDVVPGSHLTPIERESSSPLSSNQSEPGSIALNSYHSRNCSESDHSRNGFDTDSSCLESHSSLSDSEFPPNNKGEIKTEGQELITVIKAPTSFGYDKPHVLVDLLVDDSGKESLIGYRPTEDSKEFS | astrocyte activation cellular response to virus cytokine-mediated signaling pathway microglial cell activation negative regulation of amyloid-beta clearance positive regulation of amyloid-beta formation positive regulation of gene expression positive regulation of tumor necrosis factor production response to virus signal transduction type II interferon-mediated signaling pathway type III interferon-mediated signaling pathway membrane; plasma membrane cytokine binding cytokine receptor activity type II interferon receptor activity Homo sapiens 3D-structure Alternative splicing Cell membrane Direct protein sequencing Disease variant Disulfide bond Glycoprotein Immunoglobulin domain Membrane Phosphoprotein Receptor Reference proteome Signal Transmembrane Transmembrane helix Ubl conjugation MALLFLLPLV MALLFLLPLVMQGVSRAEMGTADLGPSSVPTPTNVTIESYNMNPIVYWEYQIMPQVPVFTVEVKNYGVKNSEWIDACINISHHYCNISDHVGDPSNSLWVRVKARVGQKESAYAKSEEFAVCRDGKIGPPKLDIRKEEKQIMIDIFHPSVFVNGDEQEVDYDPETTCYIRVYNVYVRMNGSEIQYKILTQKEDDCDEIQCQLAIPVSSLNSQYCVSAEGVLHVWGVTTEKSKEVCITIFNSSIKGSLWIPVVAALLLFLVLSLVFICFYIKKINPLKEKSIILPKSLISVVRSATLETKPESKYVSLITSYQPFSLEKEVVCEEPLSPATVPGMHTEDNPGKVEHTEELSSITEVVTTEENIPDVVPGSHLTPIERESSSPLSSNQSEPGSIALNSYHSRNCSESDHSRNGFDTDSSCLESHSSLSDSEFPPNNKGEIKTEGQELITVIKAPTSFGYDKPHVLVDLLVDDSGKESLIGYRPTEDSKEFS |
astrocyte activation cytokine-mediated signaling pathway defense response to virus microglial cell activation negative regulation of amyloid-beta clearance positive regulation of amyloid-beta formation positive regulation of gene expression positive regulation of tumor necrosis factor production type II interferon-mediated signaling pathway type III interferon-mediated signaling pathway | dendrite; membrane; plasma membrane; vesicle | cytokine binding cytokine receptor activity type II interferon receptor activity | Mus musculus | Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Immunoglobulin domain Membrane Phosphoprotein Receptor Reference proteome Signal Transmembrane Transmembrane helix Ubl conjugation | MGPQAAAGRM | MGPQAAAGRMILLVVLMLSAKVGSGALTSTEDPEPPSVPVPTNVLIKSYNLNPVVCWEYQNMSQTPIFTVQVKVYSGSWTDSCTNISDHCCNIYEQIMYPDVSAWARVKAKVGQKESDYARSKEFLMCLKGKVGPPGLEIRRKKEEQLSVLVFHPEVVVNGESQGTMFGDGSTCYTFDYTVYVEHNRSGEILHTKHTVEKEECNETLCELNISVSTLDSRYCISVDGISSFWQVRTEKSKDVCIPPFHDDRKDSIWILVVAPLTVFTVVILVFAYWYTKKNSFKRKSIMLPKSLLSVVKSATLETKPESKYSLVTPHQPAVLESETVICEEPLSTVTAPDSPEAAEQEELSKETKALEAGGSTSAMTPDSPPTPTQRRSFSLLSSNQSGPCSLTAYHSRNGSDSGLVGSGSSISDLESLPNNNSETKMAEHDPPPVRKAPMASGYDKPHMLVDVLVDVGGKESLMGYRLTGEAQELS | astrocyte activation cytokine-mediated signaling pathway defense response to virus microglial cell activation negative regulation of amyloid-beta clearance positive regulation of amyloid-beta formation positive regulation of gene expression positive regulation of tumor necrosis factor production type II interferon-mediated signaling pathway type III interferon-mediated signaling pathway dendrite; membrane; plasma membrane; vesicle cytokine binding cytokine receptor activity type II interferon receptor activity Mus musculus Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Immunoglobulin domain Membrane Phosphoprotein Receptor Reference proteome Signal Transmembrane Transmembrane helix Ubl conjugation MGPQAAAGRM MGPQAAAGRMILLVVLMLSAKVGSGALTSTEDPEPPSVPVPTNVLIKSYNLNPVVCWEYQNMSQTPIFTVQVKVYSGSWTDSCTNISDHCCNIYEQIMYPDVSAWARVKAKVGQKESDYARSKEFLMCLKGKVGPPGLEIRRKKEEQLSVLVFHPEVVVNGESQGTMFGDGSTCYTFDYTVYVEHNRSGEILHTKHTVEKEECNETLCELNISVSTLDSRYCISVDGISSFWQVRTEKSKDVCIPPFHDDRKDSIWILVVAPLTVFTVVILVFAYWYTKKNSFKRKSIMLPKSLLSVVKSATLETKPESKYSLVTPHQPAVLESETVICEEPLSTVTAPDSPEAAEQEELSKETKALEAGGSTSAMTPDSPPTPTQRRSFSLLSSNQSGPCSLTAYHSRNGSDSGLVGSGSSISDLESLPNNNSETKMAEHDPPPVRKAPMASGYDKPHMLVDVLVDVGGKESLMGYRLTGEAQELS |
AMP metabolic process guanine salvage IMP biosynthetic process IMP salvage purine nucleotide metabolic process | cytoplasm; cytosol | AMP deaminase activity metal ion binding | Saccharomyces cerevisiae | Direct protein sequencing Hydrolase Metal-binding Nucleotide metabolism Phosphoprotein Reference proteome Zinc | MDNQATQRLN | MDNQATQRLNDLSLEPAPSHDEQDGSGLVIDIDQRKIGDEQAGVVVDDETPPLEQQDSHESLAADSRNANFSYHENQQLLENGTKQLALDEHDSHSAILEQPSHSTNCSSSNIAAMNKGHDSADHASQNSGGKPRTLSASAQHILPETLKSFAGAPVVNKQVRTSASYKMGMLADDASQQFLDDPSSELIDLYSKVAECRNLRAKYQTISVQNDDQNPKNKPGWVVYPPPPKPSYNSDTKTVVPVTNKPDAEVFDFTKCEIPGEDPDWEFTLNDDDSYVVHRSGKTDELIAQIPTLRDYYLDLEKMISISSDGPAKSFAYRRLQYLEARWNLYYLLNEYQETSVSKRNPHRDFYNVRKVDTHVHHSACMNQKHLLRFIKHKLRHSKDEKVIFRDGKLLTLDEVFRSLHLTGYDLSIDTLDMHAHKDTFHRFDKFNLKYNPIGESRLREIFLKTNNYIKGTYLADITKQVIFDLENSKYQNCEYRISVYGRSLDEWDKLASWVIDNKVISHNVRWLVQIPRLYDIYKKTGIVQSFQDICKNLFQPLFEVTKNPQSHPKLHVFLQRVIGFDSVDDESKVDRRFHRKYPKPSLWEAPQNPPYSYYLYYLYSNVASLNQWRAKRGFNTLVLRPHCGEAGDPEHLVSAYLLAHGISHGILLRKVPFVQYLYYLDQVGIAMSPLSNNALFLTYDKNPFPRYFKRGLNVSLSTDDPLQFSYTREPLIEEYSVAAQIYKLSNVDMCELARNSVLQSGWEAQIKKHWIGKDFDKSGVEGNDVVRTNVPDIRINYRYDTLSTELELVNHFANFKRTIEEK | AMP metabolic process guanine salvage IMP biosynthetic process IMP salvage purine nucleotide metabolic process cytoplasm; cytosol AMP deaminase activity metal ion binding Saccharomyces cerevisiae Direct protein sequencing Hydrolase Metal-binding Nucleotide metabolism Phosphoprotein Reference proteome Zinc MDNQATQRLN MDNQATQRLNDLSLEPAPSHDEQDGSGLVIDIDQRKIGDEQAGVVVDDETPPLEQQDSHESLAADSRNANFSYHENQQLLENGTKQLALDEHDSHSAILEQPSHSTNCSSSNIAAMNKGHDSADHASQNSGGKPRTLSASAQHILPETLKSFAGAPVVNKQVRTSASYKMGMLADDASQQFLDDPSSELIDLYSKVAECRNLRAKYQTISVQNDDQNPKNKPGWVVYPPPPKPSYNSDTKTVVPVTNKPDAEVFDFTKCEIPGEDPDWEFTLNDDDSYVVHRSGKTDELIAQIPTLRDYYLDLEKMISISSDGPAKSFAYRRLQYLEARWNLYYLLNEYQETSVSKRNPHRDFYNVRKVDTHVHHSACMNQKHLLRFIKHKLRHSKDEKVIFRDGKLLTLDEVFRSLHLTGYDLSIDTLDMHAHKDTFHRFDKFNLKYNPIGESRLREIFLKTNNYIKGTYLADITKQVIFDLENSKYQNCEYRISVYGRSLDEWDKLASWVIDNKVISHNVRWLVQIPRLYDIYKKTGIVQSFQDICKNLFQPLFEVTKNPQSHPKLHVFLQRVIGFDSVDDESKVDRRFHRKYPKPSLWEAPQNPPYSYYLYYLYSNVASLNQWRAKRGFNTLVLRPHCGEAGDPEHLVSAYLLAHGISHGILLRKVPFVQYLYYLDQVGIAMSPLSNNALFLTYDKNPFPRYFKRGLNVSLSTDDPLQFSYTREPLIEEYSVAAQIYKLSNVDMCELARNSVLQSGWEAQIKKHWIGKDFDKSGVEGNDVVRTNVPDIRINYRYDTLSTELELVNHFANFKRTIEEK |
glycogen biosynthetic process starch biosynthetic process starch metabolic process | amyloplast; chloroplast; cytosol | ATP binding glucose-1-phosphate adenylyltransferase activity | Oryza sativa subsp. japonica | Allosteric enzyme Alternative splicing Amyloplast ATP-binding Chloroplast Cytoplasm Nucleotide-binding Nucleotidyltransferase Plastid Reference proteome Starch biosynthesis Transferase Transit peptide | MAMAAAMGVA | MAMAAAMGVASPYHAAHAAASTSCDSLRLLVAEGRPRRPRGVASSSSSSSSAGRRRRPLVFSPRAVSDSKSSQTCLDPDASTSVLGIILGGGAGTRLYPLTKKRAKPAVPLGANYRLIDIPVSNCLNSNISKIYVLTQFNSASLNRHLSRAYGNNIGGYKNEGFVEVLAAQQSPDNPNWFQGTADAVRQYLWLFEEHNVMEFLILAGDHLYRMDYEKFIQAHRETDSDITVAALPMDEKRATAFGLMKIDEEGRIVEFAEKPKGEQLKAMMVDTTILGLDDVRAKEMPYIASMGIYVISKNVMLQLLREQFPGANDFGSEVIPGATNIGMRVQAYLYDGYWEDIGTIEAFYNANLGITKKPVPDFSFYDRSAPIYTQPRHLPPSKVLDADVTDSVIGEGCVIKNCKIHHSVVGLRSCISEGAIIEDSLLMGADYYETEADKKLLGEKGGIPIGIGKNCHIRRAIIDKNARIGDNVKIINVDNVQEAARETDGYFIKSGIVTVIKDALLPSGTVI | glycogen biosynthetic process starch biosynthetic process starch metabolic process amyloplast; chloroplast; cytosol ATP binding glucose-1-phosphate adenylyltransferase activity Oryza sativa subsp. japonica Allosteric enzyme Alternative splicing Amyloplast ATP-binding Chloroplast Cytoplasm Nucleotide-binding Nucleotidyltransferase Plastid Reference proteome Starch biosynthesis Transferase Transit peptide MAMAAAMGVA MAMAAAMGVASPYHAAHAAASTSCDSLRLLVAEGRPRRPRGVASSSSSSSSAGRRRRPLVFSPRAVSDSKSSQTCLDPDASTSVLGIILGGGAGTRLYPLTKKRAKPAVPLGANYRLIDIPVSNCLNSNISKIYVLTQFNSASLNRHLSRAYGNNIGGYKNEGFVEVLAAQQSPDNPNWFQGTADAVRQYLWLFEEHNVMEFLILAGDHLYRMDYEKFIQAHRETDSDITVAALPMDEKRATAFGLMKIDEEGRIVEFAEKPKGEQLKAMMVDTTILGLDDVRAKEMPYIASMGIYVISKNVMLQLLREQFPGANDFGSEVIPGATNIGMRVQAYLYDGYWEDIGTIEAFYNANLGITKKPVPDFSFYDRSAPIYTQPRHLPPSKVLDADVTDSVIGEGCVIKNCKIHHSVVGLRSCISEGAIIEDSLLMGADYYETEADKKLLGEKGGIPIGIGKNCHIRRAIIDKNARIGDNVKIINVDNVQEAARETDGYFIKSGIVTVIKDALLPSGTVI |
peptide catabolic process proteolysis | cytosol | alanylglutamate dipeptidase activity dipeptidase activity metallodipeptidase activity protein homodimerization activity zinc ion binding | Escherichia coli | Acetylation Cobalt Dipeptidase Direct protein sequencing Hydrolase Metal-binding Metalloprotease Protease Reference proteome Zinc | MSELSQLSPQ | MSELSQLSPQPLWDIFAKICSIPHPSYHEEQLAEYIVGWAKEKGFHVERDQVGNILIRKPATAGMENRKPVVLQAHLDMVPQKNNDTVHDFTKDPIQPYIDGEWVKARGTTLGADNGIGMASALAVLADENVVHGPLEVLLTMTEEAGMDGAFGLQGNWLQADILINTDSEEEGEIYMGCAGGIDFTSNLHLDREAVPAGFETFKLTLKGLKGGHSGGEIHVGLGNANKLLVRFLAGHAEELDLRLIDFNGGTLRNAIPREAFATIAVAADKVDVLKSLVNTYQEILKNELAEKEKNLALLLDSVANDKAALIAKSRDTFIRLLNATPNGVIRNSDVAKGVVETSLNVGVVTMTDNNVEIHCLIRSLIDSGKDYVVSMLDSLGKLAGAKTEAKGAYPGWQPDANSPVMHLVRETYQRLFNKTPNIQIIHAGLECGLFKKPYPEMDMVSIGPTITGPHSPDEQVHIESVGHYWTLLTELLKEIPAK | peptide catabolic process proteolysis cytosol alanylglutamate dipeptidase activity dipeptidase activity metallodipeptidase activity protein homodimerization activity zinc ion binding Escherichia coli Acetylation Cobalt Dipeptidase Direct protein sequencing Hydrolase Metal-binding Metalloprotease Protease Reference proteome Zinc MSELSQLSPQ MSELSQLSPQPLWDIFAKICSIPHPSYHEEQLAEYIVGWAKEKGFHVERDQVGNILIRKPATAGMENRKPVVLQAHLDMVPQKNNDTVHDFTKDPIQPYIDGEWVKARGTTLGADNGIGMASALAVLADENVVHGPLEVLLTMTEEAGMDGAFGLQGNWLQADILINTDSEEEGEIYMGCAGGIDFTSNLHLDREAVPAGFETFKLTLKGLKGGHSGGEIHVGLGNANKLLVRFLAGHAEELDLRLIDFNGGTLRNAIPREAFATIAVAADKVDVLKSLVNTYQEILKNELAEKEKNLALLLDSVANDKAALIAKSRDTFIRLLNATPNGVIRNSDVAKGVVETSLNVGVVTMTDNNVEIHCLIRSLIDSGKDYVVSMLDSLGKLAGAKTEAKGAYPGWQPDANSPVMHLVRETYQRLFNKTPNIQIIHAGLECGLFKKPYPEMDMVSIGPTITGPHSPDEQVHIESVGHYWTLLTELLKEIPAK |
lipid metabolic process | azurophil granule lumen; endoplasmic reticulum lumen; extracellular exosome; extracellular region; lysosomal lumen; lysosome | arylsulfatase activity calcium ion binding cerebroside-sulfatase activity sulfuric ester hydrolase activity | Homo sapiens | 3D-structure Alternative splicing Calcium Direct protein sequencing Disease variant Disulfide bond Endoplasmic reticulum Glycoprotein Hydrolase Ichthyosis Leukodystrophy Lipid metabolism Lysosome Metachromatic leukodystrophy Metal-binding Reference proteome Signal | MGAPRSLLLA | MGAPRSLLLALAAGLAVARPPNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPSRAALLTGRLPVRMGMYPGVLVPSSRGGLPLEEVTVAEVLAARGYLTGMAGKWHLGVGPEGAFLPPHQGFHRFLGIPYSHDQGPCQNLTCFPPATPCDGGCDQGLVPIPLLANLSVEAQPPWLPGLEARYMAFAHDLMADAQRQDRPFFLYYASHHTHYPQFSGQSFAERSGRGPFGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCSGLLRCGKGTTYEGGVREPALAFWPGHIAPGVTHELASSLDLLPTLAALAGAPLPNVTLDGFDLSPLLLGTGKSPRQSLFFYPSYPDEVRGVFAVRTGKYKAHFFTQGSAHSDTTADPACHASSSLTAHEPPLLYDLSKDPGENYNLLGGVAGATPEVLQALKQLQLLKAQLDAAVTFGPSQVARGEDPALQICCHPGCTPRPACCHCPDPHA | lipid metabolic process azurophil granule lumen; endoplasmic reticulum lumen; extracellular exosome; extracellular region; lysosomal lumen; lysosome arylsulfatase activity calcium ion binding cerebroside-sulfatase activity sulfuric ester hydrolase activity Homo sapiens 3D-structure Alternative splicing Calcium Direct protein sequencing Disease variant Disulfide bond Endoplasmic reticulum Glycoprotein Hydrolase Ichthyosis Leukodystrophy Lipid metabolism Lysosome Metachromatic leukodystrophy Metal-binding Reference proteome Signal MGAPRSLLLA MGAPRSLLLALAAGLAVARPPNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPSRAALLTGRLPVRMGMYPGVLVPSSRGGLPLEEVTVAEVLAARGYLTGMAGKWHLGVGPEGAFLPPHQGFHRFLGIPYSHDQGPCQNLTCFPPATPCDGGCDQGLVPIPLLANLSVEAQPPWLPGLEARYMAFAHDLMADAQRQDRPFFLYYASHHTHYPQFSGQSFAERSGRGPFGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCSGLLRCGKGTTYEGGVREPALAFWPGHIAPGVTHELASSLDLLPTLAALAGAPLPNVTLDGFDLSPLLLGTGKSPRQSLFFYPSYPDEVRGVFAVRTGKYKAHFFTQGSAHSDTTADPACHASSSLTAHEPPLLYDLSKDPGENYNLLGGVAGATPEVLQALKQLQLLKAQLDAAVTFGPSQVARGEDPALQICCHPGCTPRPACCHCPDPHA |
acute inflammatory response angiogenesis involved in wound healing binding of sperm to zona pellucida cell adhesion development of secondary sexual characteristics epithelial cell development epithelial cell proliferation extracellular matrix organization galactose metabolic process lactose biosynthetic process lipid metabolic process macrophage migration negative regulation of epithelial cell proliferation oligosaccharide biosynthetic process penetration of zona pellucida positive regulation of apoptotic process positive regulation of circulating fibrinogen levels positive regulation of epithelial cell proliferation involved in wound healing protein N-linked glycosylation regulation of acrosome reaction | azurophil granule membrane; basolateral plasma membrane; brush border membrane; desmosome; external side of plasma membrane; extracellular exosome; extracellular space; filopodium; Golgi apparatus; Golgi cisterna membrane; Golgi membrane; Golgi trans cisterna; membrane; plasma membrane; protein-containing complex; secretory granule membrane | alpha-tubulin binding beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity beta-tubulin binding cytoskeletal protein binding galactosyltransferase activity identical protein binding lactose synthase activity manganese ion binding N-acetyllactosamine synthase activity UDP-galactosyltransferase activity | Homo sapiens | 3D-structure Alternative initiation Cell membrane Cell projection Congenital disorder of glycosylation Direct protein sequencing Disease variant Disulfide bond Glycoprotein Glycosyltransferase Golgi apparatus Lipid metabolism Manganese Membrane Metal-binding Reference proteome Secreted Signal-anchor Transferase Transmembrane Transmembrane helix | MRLREPLLSG | MRLREPLLSGSAAMPGASLQRACRLLVAVCALHLGVTLVYYLAGRDLSRLPQLVGVSTPLQGGSNSAAAIGQSSGELRTGGARPPPPLGASSQPRPGGDSSPVVDSGPGPASNLTSVPVPHTTALSLPACPEESPLLVGPMLIEFNMPVDLELVAKQNPNVKMGGRYAPRDCVSPHKVAIIIPFRNRQEHLKYWLYYLHPVLQRQQLDYGIYVINQAGDTIFNRAKLLNVGFQEALKDYDYTCFVFSDVDLIPMNDHNAYRCFSQPRHISVAMDKFGFSLPYVQYFGGVSALSKQQFLTINGFPNNYWGWGGEDDDIFNRLVFRGMSISRPNAVVGRCRMIRHSRDKKNEPNPQRFDRIAHTKETMLSDGLNSLTYQVLDVQRYPLYTQITVDIGTPS | acute inflammatory response angiogenesis involved in wound healing binding of sperm to zona pellucida cell adhesion development of secondary sexual characteristics epithelial cell development epithelial cell proliferation extracellular matrix organization galactose metabolic process lactose biosynthetic process lipid metabolic process macrophage migration negative regulation of epithelial cell proliferation oligosaccharide biosynthetic process penetration of zona pellucida positive regulation of apoptotic process positive regulation of circulating fibrinogen levels positive regulation of epithelial cell proliferation involved in wound healing protein N-linked glycosylation regulation of acrosome reaction azurophil granule membrane; basolateral plasma membrane; brush border membrane; desmosome; external side of plasma membrane; extracellular exosome; extracellular space; filopodium; Golgi apparatus; Golgi cisterna membrane; Golgi membrane; Golgi trans cisterna; membrane; plasma membrane; protein-containing complex; secretory granule membrane alpha-tubulin binding beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity beta-tubulin binding cytoskeletal protein binding galactosyltransferase activity identical protein binding lactose synthase activity manganese ion binding N-acetyllactosamine synthase activity UDP-galactosyltransferase activity Homo sapiens 3D-structure Alternative initiation Cell membrane Cell projection Congenital disorder of glycosylation Direct protein sequencing Disease variant Disulfide bond Glycoprotein Glycosyltransferase Golgi apparatus Lipid metabolism Manganese Membrane Metal-binding Reference proteome Secreted Signal-anchor Transferase Transmembrane Transmembrane helix MRLREPLLSG MRLREPLLSGSAAMPGASLQRACRLLVAVCALHLGVTLVYYLAGRDLSRLPQLVGVSTPLQGGSNSAAAIGQSSGELRTGGARPPPPLGASSQPRPGGDSSPVVDSGPGPASNLTSVPVPHTTALSLPACPEESPLLVGPMLIEFNMPVDLELVAKQNPNVKMGGRYAPRDCVSPHKVAIIIPFRNRQEHLKYWLYYLHPVLQRQQLDYGIYVINQAGDTIFNRAKLLNVGFQEALKDYDYTCFVFSDVDLIPMNDHNAYRCFSQPRHISVAMDKFGFSLPYVQYFGGVSALSKQQFLTINGFPNNYWGWGGEDDDIFNRLVFRGMSISRPNAVVGRCRMIRHSRDKKNEPNPQRFDRIAHTKETMLSDGLNSLTYQVLDVQRYPLYTQITVDIGTPS |
COPII-coated vesicle cargo loading intracellular protein transport macroautophagy positive regulation of ER to Golgi vesicle-mediated transport positive regulation of protein exit from endoplasmic reticulum regulation of COPII vesicle coating reticulophagy | COPII vesicle coat; endoplasmic reticulum; endoplasmic reticulum exit site; endoplasmic reticulum membrane; Golgi membrane | GTPase activator activity zinc ion binding | Saccharomyces cerevisiae | 3D-structure Acetylation Cytoplasm Cytoplasmic vesicle Endoplasmic reticulum ER-Golgi transport Golgi apparatus Membrane Metal-binding Protein transport Reference proteome Transport Ubl conjugation Zinc | MDFETNEDIN | MDFETNEDINGVRFTWNVFPSTRSDANSNVVPVGCLYTPLKEYDELNVAPYNPVVCSGPHCKSILNPYCVIDPRNSSWSCPICNSRNHLPPQYTNLSQENMPLELQSTTIEYITNKPVTVPPIFFFVVDLTSETENLDSLKESIITSLSLLPPNALIGLITYGNVVQLHDLSSETIDRCNVFRGDREYQLEALTEMLTGQKPTGPGGAASHLPNAMNKVTPFSLNRFFLPLEQVEFKLNQLLENLSPDQWSVPAGHRPLRATGSALNIASLLLQGCYKNIPARIILFASGPGTVAPGLIVNSELKDPLRSHHDIDSDHAQHYKKACKFYNQIAQRVAANGHTVDIFAGCYDQIGMSEMKQLTDSTGGVLLLTDAFSTAIFKQSYLRLFAKDEEGYLKMAFNGNMAVKTSKDLKVQGLIGHASAVKKTDANNISESEIGIGATSTWKMASLSPYHSYAIFFEIANTAANSNPMMSAPGSADRPHLAYTQFITTYQHSSGTNRIRVTTVANQLLPFGTPAIAASFDQEAAAVLMARIAVHKAETDDGADVIRWLDRTLIKLCQKYADYNKDDPQSFRLAPNFSLYPQFTYYLRRSQFLSVFNNSPDETAFYRHIFTREDTTNSLIMIQPTLTSFSMEDDPQPVLLDSISVKPNTILLLDTFFFILIYHGEQIAQWRKAGYQDDPQYADFKALLEEPKLEAAELLVDRFPLPRFIDTEAGGSQARFLLSKLNPSDNYQDMARGGSTIVLTDDVSLQNFMTHLQQVAVSGQA | COPII-coated vesicle cargo loading intracellular protein transport macroautophagy positive regulation of ER to Golgi vesicle-mediated transport positive regulation of protein exit from endoplasmic reticulum regulation of COPII vesicle coating reticulophagy COPII vesicle coat; endoplasmic reticulum; endoplasmic reticulum exit site; endoplasmic reticulum membrane; Golgi membrane GTPase activator activity zinc ion binding Saccharomyces cerevisiae 3D-structure Acetylation Cytoplasm Cytoplasmic vesicle Endoplasmic reticulum ER-Golgi transport Golgi apparatus Membrane Metal-binding Protein transport Reference proteome Transport Ubl conjugation Zinc MDFETNEDIN MDFETNEDINGVRFTWNVFPSTRSDANSNVVPVGCLYTPLKEYDELNVAPYNPVVCSGPHCKSILNPYCVIDPRNSSWSCPICNSRNHLPPQYTNLSQENMPLELQSTTIEYITNKPVTVPPIFFFVVDLTSETENLDSLKESIITSLSLLPPNALIGLITYGNVVQLHDLSSETIDRCNVFRGDREYQLEALTEMLTGQKPTGPGGAASHLPNAMNKVTPFSLNRFFLPLEQVEFKLNQLLENLSPDQWSVPAGHRPLRATGSALNIASLLLQGCYKNIPARIILFASGPGTVAPGLIVNSELKDPLRSHHDIDSDHAQHYKKACKFYNQIAQRVAANGHTVDIFAGCYDQIGMSEMKQLTDSTGGVLLLTDAFSTAIFKQSYLRLFAKDEEGYLKMAFNGNMAVKTSKDLKVQGLIGHASAVKKTDANNISESEIGIGATSTWKMASLSPYHSYAIFFEIANTAANSNPMMSAPGSADRPHLAYTQFITTYQHSSGTNRIRVTTVANQLLPFGTPAIAASFDQEAAAVLMARIAVHKAETDDGADVIRWLDRTLIKLCQKYADYNKDDPQSFRLAPNFSLYPQFTYYLRRSQFLSVFNNSPDETAFYRHIFTREDTTNSLIMIQPTLTSFSMEDDPQPVLLDSISVKPNTILLLDTFFFILIYHGEQIAQWRKAGYQDDPQYADFKALLEEPKLEAAELLVDRFPLPRFIDTEAGGSQARFLLSKLNPSDNYQDMARGGSTIVLTDDVSLQNFMTHLQQVAVSGQA |
blood coagulation female pregnancy negative regulation of coagulation response to cAMP response to lipopolysaccharide response to X-ray | apicolateral plasma membrane; cell surface; external side of plasma membrane; extracellular space; plasma membrane; serine-type endopeptidase complex; vacuolar membrane | calcium ion binding transmembrane signaling receptor activity | Mus musculus | Blood coagulation Disulfide bond EGF-like domain Glycoprotein Hemostasis Membrane Proteoglycan Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix | MLGIFFLGVL | MLGIFFLGVLAPASLGLSALAKLQPTGSQCVEHECFALFQGPATFLDASQACQRLQGHLMTVRSSVAADVISLLLSQSSMDLGPWIGLQLPQGCDDPVHLGPLRGFQWVTGDNHTSYSRWARPNDQTAPLCGPLCVTVSTATEAAPGEPAWEEKPCETETQGFLCEFYFTASCRPLTVNTRDPEAAHISSTYNTPFGVSGADFQTLPVGSSAAVEPLGLELVCRAPPGTSEGHWAWEATGAWNCSVENGGCEYLCNRSTNEPRCLCPRDMDLQADGRSCARPVVQSCNELCEHFCVSNAEVPGSYSCMCETGYQLAADGHRCEDVDDCKQGPNPCPQLCVNTKGGFECFCYDGYELVDGECVELLDPCFGSNCEFQCQPVSPTDYRCICAPGFAPKPDEPHKCEMFCNETSCPADCDPNSPTVCECPEGFILDEGSVCTDIDECSQGECFTSECRNFPGSYECICGPDTALAGQISKDCDPIPVREDTKEEEGSGEPPVSPTPGSPTGPPSARPVHSGVLIGISIASLSLVVALLALLCHLRKKQGAARAELEYKCASSAKEVVLQHVRTDRTLQKF | blood coagulation female pregnancy negative regulation of coagulation response to cAMP response to lipopolysaccharide response to X-ray apicolateral plasma membrane; cell surface; external side of plasma membrane; extracellular space; plasma membrane; serine-type endopeptidase complex; vacuolar membrane calcium ion binding transmembrane signaling receptor activity Mus musculus Blood coagulation Disulfide bond EGF-like domain Glycoprotein Hemostasis Membrane Proteoglycan Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix MLGIFFLGVL MLGIFFLGVLAPASLGLSALAKLQPTGSQCVEHECFALFQGPATFLDASQACQRLQGHLMTVRSSVAADVISLLLSQSSMDLGPWIGLQLPQGCDDPVHLGPLRGFQWVTGDNHTSYSRWARPNDQTAPLCGPLCVTVSTATEAAPGEPAWEEKPCETETQGFLCEFYFTASCRPLTVNTRDPEAAHISSTYNTPFGVSGADFQTLPVGSSAAVEPLGLELVCRAPPGTSEGHWAWEATGAWNCSVENGGCEYLCNRSTNEPRCLCPRDMDLQADGRSCARPVVQSCNELCEHFCVSNAEVPGSYSCMCETGYQLAADGHRCEDVDDCKQGPNPCPQLCVNTKGGFECFCYDGYELVDGECVELLDPCFGSNCEFQCQPVSPTDYRCICAPGFAPKPDEPHKCEMFCNETSCPADCDPNSPTVCECPEGFILDEGSVCTDIDECSQGECFTSECRNFPGSYECICGPDTALAGQISKDCDPIPVREDTKEEEGSGEPPVSPTPGSPTGPPSARPVHSGVLIGISIASLSLVVALLALLCHLRKKQGAARAELEYKCASSAKEVVLQHVRTDRTLQKF |
canonical NF-kappaB signal transduction inflammatory response innate immune response negative regulation of gene expression negative regulation of interferon-beta production non-canonical NF-kappaB signal transduction positive regulation of DNA-templated transcription positive regulation of interleukin-12 production positive regulation of transcription by RNA polymerase II response to cytokine | cytoplasm; nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding | Mus musculus | Acetylation DNA-binding Nucleus Phosphoprotein Proto-oncogene Reference proteome Transcription Transcription regulation | MASSGYNPYV | MASSGYNPYVEIIEQPRQRGMRFRYKCEGRSAGSIPGERSTDNNRTYPSVQIMNYYGKGKIRITLVTKNDPYKPHPHDLVGKDCRDGYYEAEFGPERRPLFFQNLGIRCVKKKEVKGAIILRISAGINPFNVGEQQLLDIEDCDLNVVRCVFMFFLPDEDGNFTTALPPIVSNPIYDNRAPNTAELRICRVNKNCGSVRGGDEIFLLCDKVQKDDIEVRFVLNDWEARGVFSQADVHRQVAIVFKTPPYCKAILEPVTVKMQLRRPSDQEVSESMDFRYLPDEKDAYGNKSKKQKTTLIFQKLLQDCGHFTEKPRTAPLGSTGEGRFIKKESNLFSHGTVLPEMPRSSGVPGQAEPYYSSCGSISSGLPHHPPAIPSVAHQPTSWPPVTHPTSHPVSTNTLSTFSAGTLSSNSQGILPFLEGPGVSDLSASNSCLYNPDDLARMETPSMSPTDLYSISDVNMLSTRPLSVMAPSTDGMGDTDNPRLVSINLENPSCNARLGPRDLRQLHQMSPASLSAGTSSSSVFVSQSDAFDRSNFSCVDNGLMNEPGLSDDANNPTFVQSSHYSVNTLQSEQLSDPFTYGFFKI | canonical NF-kappaB signal transduction inflammatory response innate immune response negative regulation of gene expression negative regulation of interferon-beta production non-canonical NF-kappaB signal transduction positive regulation of DNA-templated transcription positive regulation of interleukin-12 production positive regulation of transcription by RNA polymerase II response to cytokine cytoplasm; nucleus DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding Mus musculus Acetylation DNA-binding Nucleus Phosphoprotein Proto-oncogene Reference proteome Transcription Transcription regulation MASSGYNPYV MASSGYNPYVEIIEQPRQRGMRFRYKCEGRSAGSIPGERSTDNNRTYPSVQIMNYYGKGKIRITLVTKNDPYKPHPHDLVGKDCRDGYYEAEFGPERRPLFFQNLGIRCVKKKEVKGAIILRISAGINPFNVGEQQLLDIEDCDLNVVRCVFMFFLPDEDGNFTTALPPIVSNPIYDNRAPNTAELRICRVNKNCGSVRGGDEIFLLCDKVQKDDIEVRFVLNDWEARGVFSQADVHRQVAIVFKTPPYCKAILEPVTVKMQLRRPSDQEVSESMDFRYLPDEKDAYGNKSKKQKTTLIFQKLLQDCGHFTEKPRTAPLGSTGEGRFIKKESNLFSHGTVLPEMPRSSGVPGQAEPYYSSCGSISSGLPHHPPAIPSVAHQPTSWPPVTHPTSHPVSTNTLSTFSAGTLSSNSQGILPFLEGPGVSDLSASNSCLYNPDDLARMETPSMSPTDLYSISDVNMLSTRPLSVMAPSTDGMGDTDNPRLVSINLENPSCNARLGPRDLRQLHQMSPASLSAGTSSSSVFVSQSDAFDRSNFSCVDNGLMNEPGLSDDANNPTFVQSSHYSVNTLQSEQLSDPFTYGFFKI |
adenosine metabolic process dephosphorylation lipid metabolic process lysosome organization nucleotide metabolic process positive regulation of adenosine receptor signaling pathway purine nucleobase metabolic process regulation of sensory perception of pain thiamine metabolic process | apical part of cell; azurophil granule membrane; cytosol; extracellular exosome; extracellular space; filopodium; Golgi cisterna; lysosomal membrane; lysosome; multivesicular body; nucleus; plasma membrane; vesicle membrane | 5'-nucleotidase activity acid phosphatase activity choline binding identical protein binding lysophosphatidic acid phosphatase activity molecular adaptor activity phosphatase activity protein homodimerization activity protein tyrosine phosphatase activity thiamine phosphate phosphatase activity XMP 5'-nucleosidase activity | Homo sapiens | 3D-structure Alternative splicing Amyloid Cell membrane Cytoplasm Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Lipid metabolism Lysosome Membrane Nucleus Reference proteome Secreted Signal | MRAAPLLLAR | MRAAPLLLARAASLSLGFLFLLFFWLDRSVLAKELKFVTLVFRHGDRSPIDTFPTDPIKESSWPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAMTNLAALFPPEGVSIWNPILLWQPIPVHTVPLSEDQLLYLPFRNCPRFQELESETLKSEEFQKRLHPYKDFIATLGKLSGLHGQDLFGIWSKVYDPLYCESVHNFTLPSWATEDTMTKLRELSELSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSGLQMALDVYNGLLPPYASCHLTELYFEKGEYFVEMYYRNETQHEPYPLMLPGCSPSCPLERFAELVGPVIPQDWSTECMTTNSHQGTEDSTD | adenosine metabolic process dephosphorylation lipid metabolic process lysosome organization nucleotide metabolic process positive regulation of adenosine receptor signaling pathway purine nucleobase metabolic process regulation of sensory perception of pain thiamine metabolic process apical part of cell; azurophil granule membrane; cytosol; extracellular exosome; extracellular space; filopodium; Golgi cisterna; lysosomal membrane; lysosome; multivesicular body; nucleus; plasma membrane; vesicle membrane 5'-nucleotidase activity acid phosphatase activity choline binding identical protein binding lysophosphatidic acid phosphatase activity molecular adaptor activity phosphatase activity protein homodimerization activity protein tyrosine phosphatase activity thiamine phosphate phosphatase activity XMP 5'-nucleosidase activity Homo sapiens 3D-structure Alternative splicing Amyloid Cell membrane Cytoplasm Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Lipid metabolism Lysosome Membrane Nucleus Reference proteome Secreted Signal MRAAPLLLAR MRAAPLLLARAASLSLGFLFLLFFWLDRSVLAKELKFVTLVFRHGDRSPIDTFPTDPIKESSWPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAMTNLAALFPPEGVSIWNPILLWQPIPVHTVPLSEDQLLYLPFRNCPRFQELESETLKSEEFQKRLHPYKDFIATLGKLSGLHGQDLFGIWSKVYDPLYCESVHNFTLPSWATEDTMTKLRELSELSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSGLQMALDVYNGLLPPYASCHLTELYFEKGEYFVEMYYRNETQHEPYPLMLPGCSPSCPLERFAELVGPVIPQDWSTECMTTNSHQGTEDSTD |
adult behavior ATP metabolic process calcium ion homeostasis chloride ion homeostasis inner ear morphogenesis olfactory behavior ossification pH reduction potassium ion homeostasis prostaglandin metabolic process proton transmembrane transport regulation of gene expression regulation of macroautophagy regulation of pH renal sodium excretion renal sodium ion transport renal tubular secretion renal water homeostasis sensory perception of sound synaptic vesicle lumen acidification vacuolar acidification vacuolar proton-transporting V-type ATPase complex assembly | apical plasma membrane; basolateral plasma membrane; cytoplasm; cytosol; extracellular exosome; extrinsic component of synaptic vesicle membrane; lateral plasma membrane; microvillus; vacuolar proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase, V1 domain | ATP binding protein-containing complex binding proton transmembrane transporter activity proton-transporting ATPase activity, rotational mechanism | Homo sapiens | ATP-binding Cell membrane Deafness Disease variant Hydrogen ion transport Ion transport Membrane Nucleotide-binding Reference proteome Transport | MAMEIDSRPG | MAMEIDSRPGGLPGSSCNLGAAREHMQAVTRNYITHPRVTYRTVCSVNGPLVVLDRVKFAQYAEIVHFTLPDGTQRSGQVLEVAGTKAIVQVFEGTSGIDARKTTCEFTGDILRTPVSEDMLGRVFNGSGKPIDKGPVVMAEDFLDINGQPINPHSRIYPEEMIQTGISPIDVMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKAVLDYHDDNFAIVFAAMGVNMETARFFKSDFEQNGTMGNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRGGSITQIPILTMPNDDITHPIPDLTGFITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYACYAIGKDVQAMKAVVGEEALTSEDLLYLEFLQKFEKNFINQGPYENRSVFESLDLGWKLLRIFPKEMLKRIPQAVIDEFYSREGALQDLAPDTAL | adult behavior ATP metabolic process calcium ion homeostasis chloride ion homeostasis inner ear morphogenesis olfactory behavior ossification pH reduction potassium ion homeostasis prostaglandin metabolic process proton transmembrane transport regulation of gene expression regulation of macroautophagy regulation of pH renal sodium excretion renal sodium ion transport renal tubular secretion renal water homeostasis sensory perception of sound synaptic vesicle lumen acidification vacuolar acidification vacuolar proton-transporting V-type ATPase complex assembly apical plasma membrane; basolateral plasma membrane; cytoplasm; cytosol; extracellular exosome; extrinsic component of synaptic vesicle membrane; lateral plasma membrane; microvillus; vacuolar proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase, V1 domain ATP binding protein-containing complex binding proton transmembrane transporter activity proton-transporting ATPase activity, rotational mechanism Homo sapiens ATP-binding Cell membrane Deafness Disease variant Hydrogen ion transport Ion transport Membrane Nucleotide-binding Reference proteome Transport MAMEIDSRPG MAMEIDSRPGGLPGSSCNLGAAREHMQAVTRNYITHPRVTYRTVCSVNGPLVVLDRVKFAQYAEIVHFTLPDGTQRSGQVLEVAGTKAIVQVFEGTSGIDARKTTCEFTGDILRTPVSEDMLGRVFNGSGKPIDKGPVVMAEDFLDINGQPINPHSRIYPEEMIQTGISPIDVMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKAVLDYHDDNFAIVFAAMGVNMETARFFKSDFEQNGTMGNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRGGSITQIPILTMPNDDITHPIPDLTGFITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYACYAIGKDVQAMKAVVGEEALTSEDLLYLEFLQKFEKNFINQGPYENRSVFESLDLGWKLLRIFPKEMLKRIPQAVIDEFYSREGALQDLAPDTAL |
intracellular copper ion homeostasis intracellular iron ion homeostasis positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II response to copper ion | nucleus | copper ion binding DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding | Saccharomyces cerevisiae | Activator Copper DNA-binding Metal-binding Nucleus Reference proteome Transcription Transcription regulation Zinc | MVVINGVKYA | MVVINGVKYACETCIRGHRAAQCTHTDGPLQMIRRKGRPSTTCGHCKELRRTKNFNPSGGCMCASARRPAVGSKEDETRCRCDEGEPCKCHTKRKSSRKSKGGSCHRRANDEAAHVNGLGIADLDVLLGLNGRSSDVDMTTTLPSLKPPLQNGEIKADSIDNLDLASLDPLEQSPSISMEPVSINETGSAYTTTNTALNDIDIPFSINELNELYKQVSSHNSHSQ | intracellular copper ion homeostasis intracellular iron ion homeostasis positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II response to copper ion nucleus copper ion binding DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding Saccharomyces cerevisiae Activator Copper DNA-binding Metal-binding Nucleus Reference proteome Transcription Transcription regulation Zinc MVVINGVKYA MVVINGVKYACETCIRGHRAAQCTHTDGPLQMIRRKGRPSTTCGHCKELRRTKNFNPSGGCMCASARRPAVGSKEDETRCRCDEGEPCKCHTKRKSSRKSKGGSCHRRANDEAAHVNGLGIADLDVLLGLNGRSSDVDMTTTLPSLKPPLQNGEIKADSIDNLDLASLDPLEQSPSISMEPVSINETGSAYTTTNTALNDIDIPFSINELNELYKQVSSHNSHSQ |
anterior neural tube closure axon regeneration cardiac neural crest cell migration involved in outflow tract morphogenesis cell adhesion cellular response to folic acid folic acid metabolic process folic acid transport fusion of sperm to egg plasma membrane involved in single fertilization heart looping neural crest cell migration involved in heart formation pharyngeal arch artery morphogenesis receptor-mediated endocytosis regulation of canonical Wnt signaling pathway regulation of transforming growth factor beta receptor signaling pathway sperm-egg recognition | apical plasma membrane; basolateral plasma membrane; brush border membrane; cell surface; clathrin-coated vesicle; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment membrane; endosome; ER to Golgi transport vesicle membrane; external side of plasma membrane; extracellular exosome; Golgi membrane; membrane; nucleus; plasma membrane; transport vesicle | folic acid binding folic acid receptor activity signaling receptor activity | Homo sapiens | 3D-structure Cell membrane Cytoplasmic vesicle Direct protein sequencing Disulfide bond Endosome Folate-binding Glycoprotein GPI-anchor Lipoprotein Membrane Neurodegeneration Receptor Reference proteome Secreted Signal Transport | MAQRMTTQLL | MAQRMTTQLLLLLVWVAVVGEAQTRIAWARTELLNVCMNAKHHKEKPGPEDKLHEQCRPWRKNACCSTNTSQEAHKDVSYLYRFNWNHCGEMAPACKRHFIQDTCLYECSPNLGPWIQQVDQSWRKERVLNVPLCKEDCEQWWEDCRTSYTCKSNWHKGWNWTSGFNKCAVGAACQPFHFYFPTPTVLCNEIWTHSYKVSNYSRGSGRCIQMWFDPAQGNPNEEVARFYAAAMSGAGPWAAWPFLLSLALMLLWLLS | anterior neural tube closure axon regeneration cardiac neural crest cell migration involved in outflow tract morphogenesis cell adhesion cellular response to folic acid folic acid metabolic process folic acid transport fusion of sperm to egg plasma membrane involved in single fertilization heart looping neural crest cell migration involved in heart formation pharyngeal arch artery morphogenesis receptor-mediated endocytosis regulation of canonical Wnt signaling pathway regulation of transforming growth factor beta receptor signaling pathway sperm-egg recognition apical plasma membrane; basolateral plasma membrane; brush border membrane; cell surface; clathrin-coated vesicle; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment membrane; endosome; ER to Golgi transport vesicle membrane; external side of plasma membrane; extracellular exosome; Golgi membrane; membrane; nucleus; plasma membrane; transport vesicle folic acid binding folic acid receptor activity signaling receptor activity Homo sapiens 3D-structure Cell membrane Cytoplasmic vesicle Direct protein sequencing Disulfide bond Endosome Folate-binding Glycoprotein GPI-anchor Lipoprotein Membrane Neurodegeneration Receptor Reference proteome Secreted Signal Transport MAQRMTTQLL MAQRMTTQLLLLLVWVAVVGEAQTRIAWARTELLNVCMNAKHHKEKPGPEDKLHEQCRPWRKNACCSTNTSQEAHKDVSYLYRFNWNHCGEMAPACKRHFIQDTCLYECSPNLGPWIQQVDQSWRKERVLNVPLCKEDCEQWWEDCRTSYTCKSNWHKGWNWTSGFNKCAVGAACQPFHFYFPTPTVLCNEIWTHSYKVSNYSRGSGRCIQMWFDPAQGNPNEEVARFYAAAMSGAGPWAAWPFLLSLALMLLWLLS |
canonical NF-kappaB signal transduction dorsal/ventral axis specification dorsal/ventral pattern formation immune response innate immune response melanization defense response non-canonical NF-kappaB signal transduction peripheral nervous system neuron development positive regulation of antimicrobial peptide production positive regulation of hemocyte differentiation positive regulation of hemocyte proliferation positive regulation of transcription by RNA polymerase II regulation of hemocyte proliferation response to cytokine Toll signaling pathway | cytoplasm; cytosol; neuromuscular junction; nucleoplasm; nucleus; subsynaptic reticulum | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor binding high mobility group box 1 binding identical protein binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific DNA binding | Drosophila melanogaster | Activator Alternative splicing Cytoplasm Developmental protein DNA-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MFPNQNNGAA | MFPNQNNGAAPGQGPAVDGQQSLNYNGLPAQQQQQLAQSTKNVRKKPYVKITEQPAGKALRFRYECEGRSAGSIPGVNSTPENKTYPTIEIVGYKGRAVVVVSCVTKDTPYRPHPHNLVGKEGCKKGVCTLEINSETMRAVFSNLGIQCVKKKDIEAALKAREEIRVDPFKTGFSHRFQPSSIDLNSVRLCFQVFMESEQKGRFTSPLPPVVSEPIFDKKAMSDLVICRLCSCSATVFGNTQIILLCEKVAKEDISVRFFEEKNGQSVWEAFGDFQHTDVHKQTAITFKTPRYHTLDITEPAKVFIQLRRPSDGVTSEALPFEYVPMDSGKHTFWNLHRHLKRKPDEDLFQQILRLDAKREVQPPTIEVIDLDTPKIDVQREIPSEMEFNHEESQQSEPALEQEQSVQQEQYTQEQSLQQEQYTQEQSLQQEQYLQQLEQQQSFQLEEPMQQDQELPAQQSFDQAIDHLPDHTSDHIPEDMEAADAHAEAEAHRLRSEQEKEIDTIIDEKVRELEQLDLGQQLEPRPLTANDKITEWMKSSEIEQQVHEPSPTAEADVLDSALEISKADKTLDELLETVAELDEIYTDFKVQRDTYKNTIQNELAGLQGRAPLQVEDSFDDAATYTSLQIAFKNPVLIPMDDIMPPTPPMSQCAPEDAHQHYDPVEVNSQARKPETPMRPVPPVPPAILTIQYPPEEDKLPPLPPKRIRKQDSNAENRSIEANTVQTKPSTGESPLNKRLPPAPKNPNFNTLPRQKKPGFFSKLFSRRKSKPDLAQGQENSSILDSKANSREPSIGHFNMQDPMRASLRSSKSAAPFISNPAPAKSSPVKAKKPGSKLTKPVGRSVSSVSGKRPAYLNADVVHIPLKGDSVNSLPQQQRTEGYSQSSTISVGAGLDRRTASALQLADIPISEGGMELVAIADRQSLHNLVSSIEGHFNVQLDPNLDLTEAEHFALYTSIPPLAAASEFDETSAYYAPVDAGEILTPDEVAKRLAAANGI | canonical NF-kappaB signal transduction dorsal/ventral axis specification dorsal/ventral pattern formation immune response innate immune response melanization defense response non-canonical NF-kappaB signal transduction peripheral nervous system neuron development positive regulation of antimicrobial peptide production positive regulation of hemocyte differentiation positive regulation of hemocyte proliferation positive regulation of transcription by RNA polymerase II regulation of hemocyte proliferation response to cytokine Toll signaling pathway cytoplasm; cytosol; neuromuscular junction; nucleoplasm; nucleus; subsynaptic reticulum DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor binding high mobility group box 1 binding identical protein binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific DNA binding Drosophila melanogaster Activator Alternative splicing Cytoplasm Developmental protein DNA-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation MFPNQNNGAA MFPNQNNGAAPGQGPAVDGQQSLNYNGLPAQQQQQLAQSTKNVRKKPYVKITEQPAGKALRFRYECEGRSAGSIPGVNSTPENKTYPTIEIVGYKGRAVVVVSCVTKDTPYRPHPHNLVGKEGCKKGVCTLEINSETMRAVFSNLGIQCVKKKDIEAALKAREEIRVDPFKTGFSHRFQPSSIDLNSVRLCFQVFMESEQKGRFTSPLPPVVSEPIFDKKAMSDLVICRLCSCSATVFGNTQIILLCEKVAKEDISVRFFEEKNGQSVWEAFGDFQHTDVHKQTAITFKTPRYHTLDITEPAKVFIQLRRPSDGVTSEALPFEYVPMDSGKHTFWNLHRHLKRKPDEDLFQQILRLDAKREVQPPTIEVIDLDTPKIDVQREIPSEMEFNHEESQQSEPALEQEQSVQQEQYTQEQSLQQEQYTQEQSLQQEQYLQQLEQQQSFQLEEPMQQDQELPAQQSFDQAIDHLPDHTSDHIPEDMEAADAHAEAEAHRLRSEQEKEIDTIIDEKVRELEQLDLGQQLEPRPLTANDKITEWMKSSEIEQQVHEPSPTAEADVLDSALEISKADKTLDELLETVAELDEIYTDFKVQRDTYKNTIQNELAGLQGRAPLQVEDSFDDAATYTSLQIAFKNPVLIPMDDIMPPTPPMSQCAPEDAHQHYDPVEVNSQARKPETPMRPVPPVPPAILTIQYPPEEDKLPPLPPKRIRKQDSNAENRSIEANTVQTKPSTGESPLNKRLPPAPKNPNFNTLPRQKKPGFFSKLFSRRKSKPDLAQGQENSSILDSKANSREPSIGHFNMQDPMRASLRSSKSAAPFISNPAPAKSSPVKAKKPGSKLTKPVGRSVSSVSGKRPAYLNADVVHIPLKGDSVNSLPQQQRTEGYSQSSTISVGAGLDRRTASALQLADIPISEGGMELVAIADRQSLHNLVSSIEGHFNVQLDPNLDLTEAEHFALYTSIPPLAAASEFDETSAYYAPVDAGEILTPDEVAKRLAAANGI |
intermediate filament cytoskeleton organization | axon; C-fiber; intermediate filament; neurofilament; neuronal cell body; perikaryon; photoreceptor outer segment; photoreceptor outer segment membrane; plasma membrane; terminal bouton; type III intermediate filament | protein-containing complex binding structural molecule activity | Mus musculus | Alternative splicing Cell projection Coiled coil Cytoplasm Cytoskeleton Direct protein sequencing Intermediate filament Nitration Phosphoprotein Reference proteome | MPSSASMSHH | MPSSASMSHHHSSGLRSSISSTSYRRTFGPPPSLSPGAFSYSSSSRFSSSRLLGSGSPSSSARLGSFRAPRAGALRLPSERLDFSMAEALNQEFLATRSNEKQELQELNDRFANFIEKVRFLEQQNAALRGELSQARGQEPARADQLCQQELRELRRELELLGRERDRVQVERDGLAEDLAALKQRLEEETRKREDAEHNLVLFRKDVDDATLSRLELERKIESLMDEIEFLKKLHEEELRDLQVSVESQQVQQVEVEATVKPELTAALRDIRAQYENIAAKNLQEAEEWYKSKYADLSDAANRNHEALRQAKQEMNESRRQIQSLTCEVDGLRGTNEALLRQLRELEEQFALEAGGYQAGAARLEEELRQLKEEMARHLREYQELLNVKMALDIEIATYRKLLEGEESRISVPVHSFASLSLKTTVPEMEPLQDSHSKKMVLIRTIETRDGEKVVTESQKEQHSDLDKSSIHSY | intermediate filament cytoskeleton organization axon; C-fiber; intermediate filament; neurofilament; neuronal cell body; perikaryon; photoreceptor outer segment; photoreceptor outer segment membrane; plasma membrane; terminal bouton; type III intermediate filament protein-containing complex binding structural molecule activity Mus musculus Alternative splicing Cell projection Coiled coil Cytoplasm Cytoskeleton Direct protein sequencing Intermediate filament Nitration Phosphoprotein Reference proteome MPSSASMSHH MPSSASMSHHHSSGLRSSISSTSYRRTFGPPPSLSPGAFSYSSSSRFSSSRLLGSGSPSSSARLGSFRAPRAGALRLPSERLDFSMAEALNQEFLATRSNEKQELQELNDRFANFIEKVRFLEQQNAALRGELSQARGQEPARADQLCQQELRELRRELELLGRERDRVQVERDGLAEDLAALKQRLEEETRKREDAEHNLVLFRKDVDDATLSRLELERKIESLMDEIEFLKKLHEEELRDLQVSVESQQVQQVEVEATVKPELTAALRDIRAQYENIAAKNLQEAEEWYKSKYADLSDAANRNHEALRQAKQEMNESRRQIQSLTCEVDGLRGTNEALLRQLRELEEQFALEAGGYQAGAARLEEELRQLKEEMARHLREYQELLNVKMALDIEIATYRKLLEGEESRISVPVHSFASLSLKTTVPEMEPLQDSHSKKMVLIRTIETRDGEKVVTESQKEQHSDLDKSSIHSY |
cytoplasmic translation modification-dependent protein catabolic process protein ubiquitination ribosomal small subunit biogenesis | cytosol; cytosolic ribosome; cytosolic small ribosomal subunit; nucleolus; nucleoplasm; small-subunit processome | metal ion binding protein tag activity structural constituent of ribosome ubiquitin protein ligase binding | Drosophila melanogaster | 3D-structure Cytoplasm Isopeptide bond Metal-binding Nucleus Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation Zinc Zinc-finger | MQIFVKTLTG | MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKNYSTPKKIKHKRKKVKLAVLKYYKVDENGKIHRLRRECPGENCGAGVFMAAHEDRHYCGKCNLTFVFSKPEEK | cytoplasmic translation modification-dependent protein catabolic process protein ubiquitination ribosomal small subunit biogenesis cytosol; cytosolic ribosome; cytosolic small ribosomal subunit; nucleolus; nucleoplasm; small-subunit processome metal ion binding protein tag activity structural constituent of ribosome ubiquitin protein ligase binding Drosophila melanogaster 3D-structure Cytoplasm Isopeptide bond Metal-binding Nucleus Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation Zinc Zinc-finger MQIFVKTLTG MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKNYSTPKKIKHKRKKVKLAVLKYYKVDENGKIHRLRRECPGENCGAGVFMAAHEDRHYCGKCNLTFVFSKPEEK |
blood coagulation negative regulation of coagulation | extracellular region | heparin binding serine-type endopeptidase inhibitor activity | Haementeria officinalis | 3D-structure Blood coagulation Direct protein sequencing Disulfide bond Hemostasis Heparin-binding Protease inhibitor Pyrrolidone carboxylic acid Repeat Secreted Serine protease inhibitor Signal | MIKLAILLLF | MIKLAILLLFTVAIVRCQGPFGPGCEEAGCPEGSACNIITDRCTCSGVRCRMHCPHGFQRSRYGCEFCKCRLEPMKATCDISECPEGMMCSRLTNKCDCKIDINCRKTCPNGLKRDKLGCEYCECRPKRKLIPRLS | blood coagulation negative regulation of coagulation extracellular region heparin binding serine-type endopeptidase inhibitor activity Haementeria officinalis 3D-structure Blood coagulation Direct protein sequencing Disulfide bond Hemostasis Heparin-binding Protease inhibitor Pyrrolidone carboxylic acid Repeat Secreted Serine protease inhibitor Signal MIKLAILLLF MIKLAILLLFTVAIVRCQGPFGPGCEEAGCPEGSACNIITDRCTCSGVRCRMHCPHGFQRSRYGCEFCKCRLEPMKATCDISECPEGMMCSRLTNKCDCKIDINCRKTCPNGLKRDKLGCEYCECRPKRKLIPRLS |
protein targeting to ER signal peptide processing | endoplasmic reticulum; endoplasmic reticulum membrane; signal peptidase complex | peptidase activity serine-type endopeptidase activity | Saccharomyces cerevisiae | Endoplasmic reticulum Glycoprotein Hydrolase Membrane Protease Reference proteome Signal-anchor Transmembrane Transmembrane helix | MNLRFELQKL | MNLRFELQKLLNVCFLFASAYMFWQGLAIATNSASPIVVVLSGSMEPAFQRGDILFLWNRNTFNQVGDVVVYEVEGKQIPIVHRVLRQHNNHADKQFLLTKGDNNAGNDISLYANKKIYLNKSKEIVGTVKGYFPQLGYITIWISENKYAKFALLGMLGLSALLGGE | protein targeting to ER signal peptide processing endoplasmic reticulum; endoplasmic reticulum membrane; signal peptidase complex peptidase activity serine-type endopeptidase activity Saccharomyces cerevisiae Endoplasmic reticulum Glycoprotein Hydrolase Membrane Protease Reference proteome Signal-anchor Transmembrane Transmembrane helix MNLRFELQKL MNLRFELQKLLNVCFLFASAYMFWQGLAIATNSASPIVVVLSGSMEPAFQRGDILFLWNRNTFNQVGDVVVYEVEGKQIPIVHRVLRQHNNHADKQFLLTKGDNNAGNDISLYANKKIYLNKSKEIVGTVKGYFPQLGYITIWISENKYAKFALLGMLGLSALLGGE |
cell differentiation central nervous system development regulation of DNA-templated transcription regulation of transcription by RNA polymerase II | nucleus | estrogen response element binding nuclear receptor activity zinc ion binding | Drosophila melanogaster | Developmental protein Differentiation DNA-binding Metal-binding Neurogenesis Nucleus Receptor Reference proteome Transcription Transcription regulation Zinc Zinc-finger | MNQLCKVCGE | MNQLCKVCGEPAAGFHFGAFTCEGCKSFFGRTYNNIAAIAGCKHNGDCVINKKNRTACKACRLRKCLLVGMSKSGSRYGRRSNWFKIHCLLQEQQTTSGLGGGSSVGSGSGGGVSSASLEQLARLQQASNQARQTYQDKTNPCIKSATATTSPRIEGAAVGTGIGGGASPSFLQAAKLHHQRQLKLDSRLSNTPSDSGASSAGDPNEDGVTSVLGGQIATPSSTNATSLPKLDLRHPNFPATSEPDADMQRQRHQELLEIFRSHSEPLYSSFAPFSHLPPVLLAAGVPQLPIFKDQFKAELLFPTTSSPELEEPIDLSFRSRADPASPMAHNSNSPSLSEPAAASHCLGESTNFVRKSTPLDLTLVRSQTLTG | cell differentiation central nervous system development regulation of DNA-templated transcription regulation of transcription by RNA polymerase II nucleus estrogen response element binding nuclear receptor activity zinc ion binding Drosophila melanogaster Developmental protein Differentiation DNA-binding Metal-binding Neurogenesis Nucleus Receptor Reference proteome Transcription Transcription regulation Zinc Zinc-finger MNQLCKVCGE MNQLCKVCGEPAAGFHFGAFTCEGCKSFFGRTYNNIAAIAGCKHNGDCVINKKNRTACKACRLRKCLLVGMSKSGSRYGRRSNWFKIHCLLQEQQTTSGLGGGSSVGSGSGGGVSSASLEQLARLQQASNQARQTYQDKTNPCIKSATATTSPRIEGAAVGTGIGGGASPSFLQAAKLHHQRQLKLDSRLSNTPSDSGASSAGDPNEDGVTSVLGGQIATPSSTNATSLPKLDLRHPNFPATSEPDADMQRQRHQELLEIFRSHSEPLYSSFAPFSHLPPVLLAAGVPQLPIFKDQFKAELLFPTTSSPELEEPIDLSFRSRADPASPMAHNSNSPSLSEPAAASHCLGESTNFVRKSTPLDLTLVRSQTLTG |
deactivation of rhodopsin mediated signaling desensitization of G protein-coupled receptor signaling pathway endocytosis G protein-coupled receptor internalization metarhodopsin inactivation photoreceptor cell maintenance sensory perception of smell signal transduction visual perception | cytoplasm; rhabdomere | G protein-coupled receptor binding opsin binding | Drosophila melanogaster | Cell projection Phosphoprotein Reference proteome Sensory transduction Vision | MVVNFKVFKK | MVVNFKVFKKCSPNNMITLYMNRRDFVDSVTQVEPIDGIIVLDDEYVRQNRKIFVQLVCNFRYGREDDEMIGLRFQKELTLVSQQVCPPQKQDIQLTKMQERLLKKLGSNAYPFVMQMPPSSPASVVLQQKASDESQPCGVQYFVKIFTGDSDCDRSHRRSTINLGIRKVQYAPTKQGIQPCTVVRKDFLLSPGELELEVTLDKQLYHHGEKISVNICVRNNSNKVVKKIKAMVQQGVDVVLFQNGQFRNTIAFMETSEGCPLNPGSSLQKVMYLVPTLVANCDRAGIAVEGDIKRKDTALASTTLIASQDARDAFGIIVSYAVKVKLFLGALGGELCAELPFILMHPKPSRKAQLEAEGSIEA | deactivation of rhodopsin mediated signaling desensitization of G protein-coupled receptor signaling pathway endocytosis G protein-coupled receptor internalization metarhodopsin inactivation photoreceptor cell maintenance sensory perception of smell signal transduction visual perception cytoplasm; rhabdomere G protein-coupled receptor binding opsin binding Drosophila melanogaster Cell projection Phosphoprotein Reference proteome Sensory transduction Vision MVVNFKVFKK MVVNFKVFKKCSPNNMITLYMNRRDFVDSVTQVEPIDGIIVLDDEYVRQNRKIFVQLVCNFRYGREDDEMIGLRFQKELTLVSQQVCPPQKQDIQLTKMQERLLKKLGSNAYPFVMQMPPSSPASVVLQQKASDESQPCGVQYFVKIFTGDSDCDRSHRRSTINLGIRKVQYAPTKQGIQPCTVVRKDFLLSPGELELEVTLDKQLYHHGEKISVNICVRNNSNKVVKKIKAMVQQGVDVVLFQNGQFRNTIAFMETSEGCPLNPGSSLQKVMYLVPTLVANCDRAGIAVEGDIKRKDTALASTTLIASQDARDAFGIIVSYAVKVKLFLGALGGELCAELPFILMHPKPSRKAQLEAEGSIEA |
negative regulation of DNA-templated transcription regulation of cell growth regulation of DNA-templated transcription regulation of growth single-species biofilm formation | cytoplasm; toxin-antitoxin complex | DNA binding DNA-binding transcription factor activity enzyme binding identical protein binding toxin sequestering activity | Escherichia coli | Cytoplasm DNA-binding Reference proteome Repressor Toxin-antitoxin system Transcription Transcription regulation | MPANARSHAV | MPANARSHAVLTTESKVTIRGQTTIPAPVREALKLKPGQDSIHYEILPGGQVFMCRLGDEQEDHTMNAFLRFLDADIQNNPQKTRPFNIQQGKKLVAGMDVNIDDEIGDDE | negative regulation of DNA-templated transcription regulation of cell growth regulation of DNA-templated transcription regulation of growth single-species biofilm formation cytoplasm; toxin-antitoxin complex DNA binding DNA-binding transcription factor activity enzyme binding identical protein binding toxin sequestering activity Escherichia coli Cytoplasm DNA-binding Reference proteome Repressor Toxin-antitoxin system Transcription Transcription regulation MPANARSHAV MPANARSHAVLTTESKVTIRGQTTIPAPVREALKLKPGQDSIHYEILPGGQVFMCRLGDEQEDHTMNAFLRFLDADIQNNPQKTRPFNIQQGKKLVAGMDVNIDDEIGDDE |
post-translational protein modification protein catabolic process protein deubiquitination protein ubiquitination ubiquitin-dependent protein catabolic process | cytoplasm; cytosol; nucleoplasm | cysteine-type deubiquitinase activity deNEDDylase activity peptidase activity ubiquitin binding | Homo sapiens | 3D-structure Cytoplasm Hydrolase Phosphoprotein Protease Reference proteome Thiol protease Ubl conjugation pathway | MEGQRWLPLE | MEGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFLEESVSMSPEERARYLENYDAIRVTHETSAHEGQTEAPSIDEKVDLHFIALVHVDGHLYELDGRKPFPINHGETSDETLLEDAIEVCKKFMERDPDELRFNAIALSAA | post-translational protein modification protein catabolic process protein deubiquitination protein ubiquitination ubiquitin-dependent protein catabolic process cytoplasm; cytosol; nucleoplasm cysteine-type deubiquitinase activity deNEDDylase activity peptidase activity ubiquitin binding Homo sapiens 3D-structure Cytoplasm Hydrolase Phosphoprotein Protease Reference proteome Thiol protease Ubl conjugation pathway MEGQRWLPLE MEGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFLEESVSMSPEERARYLENYDAIRVTHETSAHEGQTEAPSIDEKVDLHFIALVHVDGHLYELDGRKPFPINHGETSDETLLEDAIEVCKKFMERDPDELRFNAIALSAA |
muscle tissue morphogenesis negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of myoblast differentiation positive regulation of skeletal muscle fiber development regulation of transcription by RNA polymerase II skeletal muscle cell differentiation skeletal muscle tissue development skeletal muscle tissue regeneration somitogenesis | cytosol; mitotic spindle; nucleoplasm; nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Mus musculus | Developmental protein Differentiation DNA-binding Myogenesis Nucleus Reference proteome | MMMDLFETGS | MMMDLFETGSYFFYLDGENVTLQPLEVAEGSPLYPGSDGTLSPCQDQMPQEAGSDSSGEEHVLAPPGLQPPHCPGQCLIWACKTCKRKSAPTDRRKAATLRERRRLKKINEAFEALKRRTVANPNQRLPKVEILRSAISYIERLQDLLHRLDQQEKMQELGVDPYSYKPKQEILEGADFLRTCSPQWPSVSDHSRGLVITAKEGGANVDASASSSLQRLSSIVDSISSEERKLPSVEEVVEK | muscle tissue morphogenesis negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of myoblast differentiation positive regulation of skeletal muscle fiber development regulation of transcription by RNA polymerase II skeletal muscle cell differentiation skeletal muscle tissue development skeletal muscle tissue regeneration somitogenesis cytosol; mitotic spindle; nucleoplasm; nucleus DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding Mus musculus Developmental protein Differentiation DNA-binding Myogenesis Nucleus Reference proteome MMMDLFETGS MMMDLFETGSYFFYLDGENVTLQPLEVAEGSPLYPGSDGTLSPCQDQMPQEAGSDSSGEEHVLAPPGLQPPHCPGQCLIWACKTCKRKSAPTDRRKAATLRERRRLKKINEAFEALKRRTVANPNQRLPKVEILRSAISYIERLQDLLHRLDQQEKMQELGVDPYSYKPKQEILEGADFLRTCSPQWPSVSDHSRGLVITAKEGGANVDASASSSLQRLSSIVDSISSEERKLPSVEEVVEK |
cardiac muscle cell action potential involved in contraction cellular response to acidic pH cellular response to cAMP cellular response to light stimulus epithelial cell maturation heart contraction male gonad development membrane repolarization membrane repolarization during action potential membrane repolarization during cardiac muscle cell action potential membrane repolarization during ventricular cardiac muscle cell action potential negative regulation of delayed rectifier potassium channel activity negative regulation of protein targeting to membrane positive regulation of potassium ion transmembrane transport potassium ion export across plasma membrane potassium ion transmembrane transport regulation of heart rate by cardiac conduction regulation of potassium ion transmembrane transport regulation of ventricular cardiac muscle cell membrane repolarization secretory granule organization ventricular cardiac muscle cell action potential vestibular nucleus development | apical plasma membrane; cell surface; membrane raft; plasma membrane; voltage-gated potassium channel complex; Z disc | delayed rectifier potassium channel activity potassium channel regulator activity protein-containing complex binding telethonin binding transmembrane transporter binding voltage-gated potassium channel activity | Rattus norvegicus | Cell membrane Glycoprotein Ion channel Ion transport Membrane Phosphoprotein Potassium Potassium channel Potassium transport Reference proteome Transmembrane Transmembrane helix Transport Voltage-gated channel | MALSNSTTVL | MALSNSTTVLPFLASLWQETDEPGGNMSADLARRSQLRDDSKLEALYILMVLGFFGFFTLGIMLSYIRSKKLEHSHDPFNVYIESDAWQEKGKALFQARVLESFRACYVIENQAAVEQPATHLPELKPLS | cardiac muscle cell action potential involved in contraction cellular response to acidic pH cellular response to cAMP cellular response to light stimulus epithelial cell maturation heart contraction male gonad development membrane repolarization membrane repolarization during action potential membrane repolarization during cardiac muscle cell action potential membrane repolarization during ventricular cardiac muscle cell action potential negative regulation of delayed rectifier potassium channel activity negative regulation of protein targeting to membrane positive regulation of potassium ion transmembrane transport potassium ion export across plasma membrane potassium ion transmembrane transport regulation of heart rate by cardiac conduction regulation of potassium ion transmembrane transport regulation of ventricular cardiac muscle cell membrane repolarization secretory granule organization ventricular cardiac muscle cell action potential vestibular nucleus development apical plasma membrane; cell surface; membrane raft; plasma membrane; voltage-gated potassium channel complex; Z disc delayed rectifier potassium channel activity potassium channel regulator activity protein-containing complex binding telethonin binding transmembrane transporter binding voltage-gated potassium channel activity Rattus norvegicus Cell membrane Glycoprotein Ion channel Ion transport Membrane Phosphoprotein Potassium Potassium channel Potassium transport Reference proteome Transmembrane Transmembrane helix Transport Voltage-gated channel MALSNSTTVL MALSNSTTVLPFLASLWQETDEPGGNMSADLARRSQLRDDSKLEALYILMVLGFFGFFTLGIMLSYIRSKKLEHSHDPFNVYIESDAWQEKGKALFQARVLESFRACYVIENQAAVEQPATHLPELKPLS |
corpus callosum development optic nerve development potassium ion transmembrane transport potassium ion transport protein homooligomerization | axon; calyx of Held; glutamatergic synapse; membrane raft; plasma membrane; postsynaptic membrane; presynaptic membrane; voltage-gated potassium channel complex | delayed rectifier potassium channel activity outward rectifier potassium channel activity voltage-gated potassium channel activity | Rattus norvegicus | Cell membrane Glycoprotein Ion channel Ion transport Lipoprotein Membrane Palmitate Phosphoprotein Potassium Potassium channel Potassium transport Reference proteome Transmembrane Transmembrane helix Transport Voltage-gated channel | MTVVPGDHLL | MTVVPGDHLLEPEAAGGGGGDPPQGGCVSGGGCDRYEPLPPALPAAGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASPSQDVFEAANNSTSGASSGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPSSGFNSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHSAFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV | corpus callosum development optic nerve development potassium ion transmembrane transport potassium ion transport protein homooligomerization axon; calyx of Held; glutamatergic synapse; membrane raft; plasma membrane; postsynaptic membrane; presynaptic membrane; voltage-gated potassium channel complex delayed rectifier potassium channel activity outward rectifier potassium channel activity voltage-gated potassium channel activity Rattus norvegicus Cell membrane Glycoprotein Ion channel Ion transport Lipoprotein Membrane Palmitate Phosphoprotein Potassium Potassium channel Potassium transport Reference proteome Transmembrane Transmembrane helix Transport Voltage-gated channel MTVVPGDHLL MTVVPGDHLLEPEAAGGGGGDPPQGGCVSGGGCDRYEPLPPALPAAGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASPSQDVFEAANNSTSGASSGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPSSGFNSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHSAFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV |
monoatomic ion transmembrane transport potassium ion transmembrane transport potassium ion transport protein homooligomerization regulation of presynaptic membrane potential | asymmetric synapse; axon; axon initial segment; cell surface; dendritic shaft; dendritic spine; glutamatergic synapse; membrane; plasma membrane; postsynaptic membrane; presynaptic membrane; voltage-gated potassium channel complex | delayed rectifier potassium channel activity monoatomic ion channel activity potassium channel activity potassium ion binding voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential voltage-gated potassium channel activity | Rattus norvegicus | 3D-structure Cell membrane Cell projection Glycoprotein Ion channel Ion transport Membrane Phosphoprotein Potassium Potassium channel Potassium transport Reference proteome Transmembrane Transmembrane helix Transport Voltage-gated channel | MEVAMVSAES | MEVAMVSAESSGCNSHMPYGYAAQARARERERLAHSRAAAAAAVAAATAAVEGTGGSGGGPHHHHQTRGAYSSHDPQGSRGSREEEATRTEKKKKLHHRQSSFPHCSDLMPSGSEEKILRELSEEEEDEEEEEEEEEEGRFYYSEEDHGDGCSYTDLLPQDDGGGGGYSSVRYSDCCERVVINVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQLGEEALLKFREDEGFVREEEDRALPENEFKKQIWLLFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLIMALSAGGHSRLLNDTSAPHLENSGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFITLGTDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEQTQLTQNAVSCPYLPSNLLKKFRSSTSSSLGDKSEYLEMEEGVKESLCGKEEKCQGKGDDSETDKNNCSNAKAVETDV | monoatomic ion transmembrane transport potassium ion transmembrane transport potassium ion transport protein homooligomerization regulation of presynaptic membrane potential asymmetric synapse; axon; axon initial segment; cell surface; dendritic shaft; dendritic spine; glutamatergic synapse; membrane; plasma membrane; postsynaptic membrane; presynaptic membrane; voltage-gated potassium channel complex delayed rectifier potassium channel activity monoatomic ion channel activity potassium channel activity potassium ion binding voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential voltage-gated potassium channel activity Rattus norvegicus 3D-structure Cell membrane Cell projection Glycoprotein Ion channel Ion transport Membrane Phosphoprotein Potassium Potassium channel Potassium transport Reference proteome Transmembrane Transmembrane helix Transport Voltage-gated channel MEVAMVSAES MEVAMVSAESSGCNSHMPYGYAAQARARERERLAHSRAAAAAAVAAATAAVEGTGGSGGGPHHHHQTRGAYSSHDPQGSRGSREEEATRTEKKKKLHHRQSSFPHCSDLMPSGSEEKILRELSEEEEDEEEEEEEEEEGRFYYSEEDHGDGCSYTDLLPQDDGGGGGYSSVRYSDCCERVVINVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQLGEEALLKFREDEGFVREEEDRALPENEFKKQIWLLFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLIMALSAGGHSRLLNDTSAPHLENSGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFITLGTDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEQTQLTQNAVSCPYLPSNLLKKFRSSTSSSLGDKSEYLEMEEGVKESLCGKEEKCQGKGDDSETDKNNCSNAKAVETDV |
action potential cellular response to calcium ion cellular response to glucose stimulus cellular response to nutrient levels clustering of voltage-gated potassium channels glucose homeostasis glutamate receptor signaling pathway negative regulation of insulin secretion positive regulation of calcium ion-dependent exocytosis positive regulation of catecholamine secretion positive regulation of long-term synaptic depression positive regulation of norepinephrine secretion positive regulation of protein targeting to membrane potassium ion export across plasma membrane potassium ion transmembrane transport potassium ion transport protein homooligomerization protein localization to plasma membrane regulation of action potential regulation of motor neuron apoptotic process response to axon injury response to L-glutamate vesicle docking involved in exocytosis | apical plasma membrane; axon; cell surface; cholinergic synapse; dendrite; dendrite membrane; lateral plasma membrane; neuronal cell body; neuronal cell body membrane; perikaryon; perinuclear region of cytoplasm; plasma membrane; postsynaptic membrane; postsynaptic specialization membrane; proximal dendrite; sarcolemma; voltage-gated potassium channel complex | delayed rectifier potassium channel activity outward rectifier potassium channel activity protein heterodimerization activity SNARE binding transmembrane transporter binding voltage-gated potassium channel activity | Rattus norvegicus | 3D-structure Cell membrane Cell projection Exocytosis Ion channel Ion transport Isopeptide bond Membrane Phosphoprotein Postsynaptic cell membrane Potassium Potassium channel Potassium transport Reference proteome Synapse Synaptosome Transmembrane Transmembrane helix Transport Ubl conjugation Voltage-gated channel | MPAGMTKHGS | MPAGMTKHGSRSTSSLPPEPMEIVRSKACSRRVRLNVGGLAHEVLWRTLDRLPRTRLGKLRDCNTHDSLLQVCDDYSLEDNEYFFDRHPGAFTSILNFYRTGRLHMMEEMCALSFSQELDYWGIDEIYLESCCQARYHQKKEQMNEELKREAETLREREGEEFDNTCCAEKRKKLWDLLEKPNSSVAAKILAIISIMFIVLSTIALSLNTLPELQSLDEFGQSTDNPQLAHVEAVCIAWFTMEYLLRFLSSPKKWKFFKGPLNAIDLLAILPYYVTIFLTESNKSVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDEDDTKFKSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVIALPIPIIVNNFSEFYKEQKRQEKAIKRREALERAKRNGSIVSMNMKDAFARSIEMMDIVVEKNGESIAKKDKVQDNHLSPNKWKWTKRALSETSSSKSFETKEQGSPEKARSSSSPQHLNVQQLEDMYSKMAKTQSQPILNTKEMAPQSKPPEELEMSSMPSPVAPLPARTEGVIDMRSMSSIDSFISCATDFPEATRFSHSPLASLSSKAGSSTAPEVGWRGALGASGGRLTETNPIPETSRSGFFVESPRSSMKTNNPLKLRALKVNFVEGDPTPLLPSLGLYHDPLRNRGGAAAAVAGLECASLLDKPVLSPESSIYTTASARTPPRSPEKHTAIAFNFEAGVHHYIDTDTDDEGQLLYSVDSSPPKSLHGSTSPKFSTGARTEKNHFESSPLPTSPKFLRPNCVYSSEGLTGKGPGAQEKCKLENHTPPDVHMLPGGGAHGSTRDQSI | action potential cellular response to calcium ion cellular response to glucose stimulus cellular response to nutrient levels clustering of voltage-gated potassium channels glucose homeostasis glutamate receptor signaling pathway negative regulation of insulin secretion positive regulation of calcium ion-dependent exocytosis positive regulation of catecholamine secretion positive regulation of long-term synaptic depression positive regulation of norepinephrine secretion positive regulation of protein targeting to membrane potassium ion export across plasma membrane potassium ion transmembrane transport potassium ion transport protein homooligomerization protein localization to plasma membrane regulation of action potential regulation of motor neuron apoptotic process response to axon injury response to L-glutamate vesicle docking involved in exocytosis apical plasma membrane; axon; cell surface; cholinergic synapse; dendrite; dendrite membrane; lateral plasma membrane; neuronal cell body; neuronal cell body membrane; perikaryon; perinuclear region of cytoplasm; plasma membrane; postsynaptic membrane; postsynaptic specialization membrane; proximal dendrite; sarcolemma; voltage-gated potassium channel complex delayed rectifier potassium channel activity outward rectifier potassium channel activity protein heterodimerization activity SNARE binding transmembrane transporter binding voltage-gated potassium channel activity Rattus norvegicus 3D-structure Cell membrane Cell projection Exocytosis Ion channel Ion transport Isopeptide bond Membrane Phosphoprotein Postsynaptic cell membrane Potassium Potassium channel Potassium transport Reference proteome Synapse Synaptosome Transmembrane Transmembrane helix Transport Ubl conjugation Voltage-gated channel MPAGMTKHGS MPAGMTKHGSRSTSSLPPEPMEIVRSKACSRRVRLNVGGLAHEVLWRTLDRLPRTRLGKLRDCNTHDSLLQVCDDYSLEDNEYFFDRHPGAFTSILNFYRTGRLHMMEEMCALSFSQELDYWGIDEIYLESCCQARYHQKKEQMNEELKREAETLREREGEEFDNTCCAEKRKKLWDLLEKPNSSVAAKILAIISIMFIVLSTIALSLNTLPELQSLDEFGQSTDNPQLAHVEAVCIAWFTMEYLLRFLSSPKKWKFFKGPLNAIDLLAILPYYVTIFLTESNKSVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDEDDTKFKSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVIALPIPIIVNNFSEFYKEQKRQEKAIKRREALERAKRNGSIVSMNMKDAFARSIEMMDIVVEKNGESIAKKDKVQDNHLSPNKWKWTKRALSETSSSKSFETKEQGSPEKARSSSSPQHLNVQQLEDMYSKMAKTQSQPILNTKEMAPQSKPPEELEMSSMPSPVAPLPARTEGVIDMRSMSSIDSFISCATDFPEATRFSHSPLASLSSKAGSSTAPEVGWRGALGASGGRLTETNPIPETSRSGFFVESPRSSMKTNNPLKLRALKVNFVEGDPTPLLPSLGLYHDPLRNRGGAAAAVAGLECASLLDKPVLSPESSIYTTASARTPPRSPEKHTAIAFNFEAGVHHYIDTDTDDEGQLLYSVDSSPPKSLHGSTSPKFSTGARTEKNHFESSPLPTSPKFLRPNCVYSSEGLTGKGPGAQEKCKLENHTPPDVHMLPGGGAHGSTRDQSI |
cellular response to xenobiotic stimulus cerebellum development corpus callosum development globus pallidus development optic nerve development positive regulation of monoatomic ion transmembrane transport positive regulation of potassium ion transmembrane transport potassium ion transmembrane transport protein homooligomerization protein tetramerization regulation of monoatomic ion transmembrane transport regulation of potassium ion transmembrane transport response to amine response to auditory stimulus response to fibroblast growth factor response to light intensity response to nerve growth factor response to potassium ion response to toxic substance | axolemma; axon terminus; calyx of Held; cell surface; dendrite; dendrite membrane; neuron projection membrane; neuronal cell body; neuronal cell body membrane; postsynaptic membrane; presynaptic membrane; voltage-gated potassium channel complex | delayed rectifier potassium channel activity kinesin binding transmembrane transporter binding voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential | Mus musculus | Alternative splicing Cell membrane Cell projection Glycoprotein Ion channel Ion transport Membrane Phosphoprotein Potassium Potassium channel Potassium transport Reference proteome Synapse Transmembrane Transmembrane helix Transport Voltage-gated channel | MGQGDESERI | MGQGDESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVVFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHIPRPPQLGSPNYCKSVVNSPHHSTQSDTCPLAQEEILEINRAGRKPLRGMSI | cellular response to xenobiotic stimulus cerebellum development corpus callosum development globus pallidus development optic nerve development positive regulation of monoatomic ion transmembrane transport positive regulation of potassium ion transmembrane transport potassium ion transmembrane transport protein homooligomerization protein tetramerization regulation of monoatomic ion transmembrane transport regulation of potassium ion transmembrane transport response to amine response to auditory stimulus response to fibroblast growth factor response to light intensity response to nerve growth factor response to potassium ion response to toxic substance axolemma; axon terminus; calyx of Held; cell surface; dendrite; dendrite membrane; neuron projection membrane; neuronal cell body; neuronal cell body membrane; postsynaptic membrane; presynaptic membrane; voltage-gated potassium channel complex delayed rectifier potassium channel activity kinesin binding transmembrane transporter binding voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential Mus musculus Alternative splicing Cell membrane Cell projection Glycoprotein Ion channel Ion transport Membrane Phosphoprotein Potassium Potassium channel Potassium transport Reference proteome Synapse Transmembrane Transmembrane helix Transport Voltage-gated channel MGQGDESERI MGQGDESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVVFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHIPRPPQLGSPNYCKSVVNSPHHSTQSDTCPLAQEEILEINRAGRKPLRGMSI |
coumarin metabolic process epoxygenase P450 pathway response to stilbenoid xenobiotic metabolic process | cytoplasm; cytoplasmic microtubule; endoplasmic reticulum membrane; intracellular membrane-bounded organelle | arachidonic acid epoxygenase activity aromatase activity coumarin 7-hydroxylase activity enzyme binding heme binding iron ion binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | Mus musculus | Acetylation Endoplasmic reticulum Heme Iron Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Phosphoprotein Reference proteome | MLTSGLLLVA | MLTSGLLLVAAVAFLSVLVLMSVWKQRKLSGKLPPGPTPLPFVGNFLQLNTEQMYNSLMKISQRYGPVFTIYLGSRRIVVLCGQETVKEALVDQAEEFSGRGEQATFDWLFKGYGIAFSSGERAKQLRRFSITTLRDFGVGKRGIEERIQEEAGFLIDSFRKTNGAFIDPTFYLSRTVSNVISSIVFGDRFDYEDKEFLSLLRMMLGSLQFTATSMGQVYEMFSSVMKHLPGPQQQAFKELQGLEDFITKKVEHNQRTLDPNSPRDFIDSFLIRMLEEKKNPNTEFYMKNLVLTTLNLFFAGTETVSTTLRYGFLLLMKYPDIEAKVHEEIDRVIGRNRQPKYEDRMKMPYTEAVIHEIQRFADLIPMGLARRVTKDTKFRDFLLPKGTEVFPMLGSVLKDPKFFSNPKDFNPKHFLDDKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFLTNIMQNFHFKSTQEPQDIDVSPRLVGFVTIPPTYTMSFLSR | coumarin metabolic process epoxygenase P450 pathway response to stilbenoid xenobiotic metabolic process cytoplasm; cytoplasmic microtubule; endoplasmic reticulum membrane; intracellular membrane-bounded organelle arachidonic acid epoxygenase activity aromatase activity coumarin 7-hydroxylase activity enzyme binding heme binding iron ion binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen Mus musculus Acetylation Endoplasmic reticulum Heme Iron Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Phosphoprotein Reference proteome MLTSGLLLVA MLTSGLLLVAAVAFLSVLVLMSVWKQRKLSGKLPPGPTPLPFVGNFLQLNTEQMYNSLMKISQRYGPVFTIYLGSRRIVVLCGQETVKEALVDQAEEFSGRGEQATFDWLFKGYGIAFSSGERAKQLRRFSITTLRDFGVGKRGIEERIQEEAGFLIDSFRKTNGAFIDPTFYLSRTVSNVISSIVFGDRFDYEDKEFLSLLRMMLGSLQFTATSMGQVYEMFSSVMKHLPGPQQQAFKELQGLEDFITKKVEHNQRTLDPNSPRDFIDSFLIRMLEEKKNPNTEFYMKNLVLTTLNLFFAGTETVSTTLRYGFLLLMKYPDIEAKVHEEIDRVIGRNRQPKYEDRMKMPYTEAVIHEIQRFADLIPMGLARRVTKDTKFRDFLLPKGTEVFPMLGSVLKDPKFFSNPKDFNPKHFLDDKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFLTNIMQNFHFKSTQEPQDIDVSPRLVGFVTIPPTYTMSFLSR |
adenosine metabolic process aldosterone biosynthetic process cellular response to peptide hormone stimulus cellular response to type II interferon cholesterol metabolic process cortisol biosynthetic process cortisol metabolic process dibenzo-p-dioxin metabolic process glucocorticoid biosynthetic process response to dexamethasone response to xenobiotic stimulus steroid biosynthetic process steroid metabolic process | mitochondrial inner membrane | corticosterone 18-monooxygenase activity heme binding iron ion binding steroid 11-beta-monooxygenase activity steroid binding | Rattus norvegicus | Direct protein sequencing Heme Iron Membrane Metal-binding Mitochondrion Mitochondrion inner membrane Monooxygenase Oxidoreductase Reference proteome Steroidogenesis Transit peptide | MALRVTADVW | MALRVTADVWLARPWQCLHRTRALGTTAKVAPKTLKPFEAIPQYSRNKWLKMIQILREQGQENLHLEMHQAFQELGPIFRHSAGGAQIVSVMLPEDAEKLHQVESILPHRMPLEPWVAHRELRGLRRGVFLLNGADWRFNRLQLNPNMLSPKAIQSFVPFVDVVARDFVENLKKRMLENVHGSMSINIQSNMFNYTMEASHFVISGERLGLTGHDLKPESVTFTHALHSMFKSTTQLMFLPKSLTRWTSTRVWKEHFDSWDIISEYVTKCIKNVYRELAEGRQQSWSVISEMVAQSTLSMDAIHANSMELIAGSVDTTAISLVMTLFELARNPDVQQALRQESLAAEASIVANPQKAMSDLPLLRAALKETLRLYPVGSFVERIVHSDLVLQNYHVPAGTFVIIYLYSMGRNPAVFPRPERYMPQRWLERKRSFQHLAFGFGVRQCLGRRLAEVEMLLLLHHMLKTFQVETLRQEDMQMVFRFLLMPSSSPFLTFRPVS | adenosine metabolic process aldosterone biosynthetic process cellular response to peptide hormone stimulus cellular response to type II interferon cholesterol metabolic process cortisol biosynthetic process cortisol metabolic process dibenzo-p-dioxin metabolic process glucocorticoid biosynthetic process response to dexamethasone response to xenobiotic stimulus steroid biosynthetic process steroid metabolic process mitochondrial inner membrane corticosterone 18-monooxygenase activity heme binding iron ion binding steroid 11-beta-monooxygenase activity steroid binding Rattus norvegicus Direct protein sequencing Heme Iron Membrane Metal-binding Mitochondrion Mitochondrion inner membrane Monooxygenase Oxidoreductase Reference proteome Steroidogenesis Transit peptide MALRVTADVW MALRVTADVWLARPWQCLHRTRALGTTAKVAPKTLKPFEAIPQYSRNKWLKMIQILREQGQENLHLEMHQAFQELGPIFRHSAGGAQIVSVMLPEDAEKLHQVESILPHRMPLEPWVAHRELRGLRRGVFLLNGADWRFNRLQLNPNMLSPKAIQSFVPFVDVVARDFVENLKKRMLENVHGSMSINIQSNMFNYTMEASHFVISGERLGLTGHDLKPESVTFTHALHSMFKSTTQLMFLPKSLTRWTSTRVWKEHFDSWDIISEYVTKCIKNVYRELAEGRQQSWSVISEMVAQSTLSMDAIHANSMELIAGSVDTTAISLVMTLFELARNPDVQQALRQESLAAEASIVANPQKAMSDLPLLRAALKETLRLYPVGSFVERIVHSDLVLQNYHVPAGTFVIIYLYSMGRNPAVFPRPERYMPQRWLERKRSFQHLAFGFGVRQCLGRRLAEVEMLLLLHHMLKTFQVETLRQEDMQMVFRFLLMPSSSPFLTFRPVS |
ATP metabolic process basophil activation involved in immune response negative regulation of inflammatory response negative regulation of mast cell activation involved in immune response negative regulation of mast cell proliferation nucleoside triphosphate catabolic process phosphate ion homeostasis pyrimidine nucleotide metabolic process | apical plasma membrane; external side of plasma membrane; extracellular region; perinuclear region of cytoplasm | calcium ion binding nucleic acid binding nucleoside triphosphate diphosphatase activity phosphodiesterase I activity zinc ion binding | Bos taurus | Calcium Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Membrane Metal-binding Reference proteome Repeat Secreted Signal-anchor Transmembrane Transmembrane helix Zinc | MQSTLNLSTE | MQSTLNLSTEEPVKRNTVKKYKIICIVLLILLVAVSLALGLVAGLRQQEEQGSCRKKCFDASHRGLEGCRCDVGCKGRGDCCWDFEDTCVQSTQIWTCNKFRCGETRLESSLCSCSDDCLQRKDCCADYKSVCQGETSWVDEDCSTAQQPQCPEGFDLPPVILFSMDGFRAEYLQTWSTLVPNINKLKTCGVHSQYLRPAYPTKTFPNHYTIVTGLYPESHGIIDNNMYDINLNKNFSLSSKEKDNPAWWQGQPIWLTAMYQGLKVGTYFWPGSDVAINGTFPSIYKIYNRSVTYEERIFTLLKWLDLPKAERPDFYTIYVEEPDSQGHNYGPVSAGVIQALQLVDKTFGLLMEGLKQRNLVNCVNIILLADHGMDQTYCDKLEYMADYFSSINFYMFEGPAPRIRTRNIPQDFFTFNSEEIVRNLSCRKPDQHFKPYLSPDLPKRLHFAKNVRIDKVNLLVDRQWQAVRNRAYSYCGGGNHGYDNEFKSMEAIFLAHGPSFKQKTEVEPFDNIEVYNLLCDLLHIQPAPNNGTHGSLNHLLKVPFYEPSHAEELSKFSVCGFTVPLPTDTLGCSCSRLQTNSDLERVNQMLDLTQDEITATEKLNLPFGRPRLIQKNKEPCLLYHREYVSGFDKTLRMPLWSSYTVPKPGDTSPLPPTVPDCLRADVRVAPSESQNCSFSLADKNITHGFLYPPANNRTSNSQYDALITSNLVPMYEAFKTMWNYFHSVLLVKYAMERNGVNVVSGPVFDYDYDGHFDAPDEIADYAVNTSVPIPTHYFVVLTSCKNQSQTPDACTGWLDVLPFVIPHRPTNVESCPENKSESLWVEERFNVHTARVRDVELLTGLDFYQEKAQPVSEILQLKTYLPVFETVI | ATP metabolic process basophil activation involved in immune response negative regulation of inflammatory response negative regulation of mast cell activation involved in immune response negative regulation of mast cell proliferation nucleoside triphosphate catabolic process phosphate ion homeostasis pyrimidine nucleotide metabolic process apical plasma membrane; external side of plasma membrane; extracellular region; perinuclear region of cytoplasm calcium ion binding nucleic acid binding nucleoside triphosphate diphosphatase activity phosphodiesterase I activity zinc ion binding Bos taurus Calcium Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Membrane Metal-binding Reference proteome Repeat Secreted Signal-anchor Transmembrane Transmembrane helix Zinc MQSTLNLSTE MQSTLNLSTEEPVKRNTVKKYKIICIVLLILLVAVSLALGLVAGLRQQEEQGSCRKKCFDASHRGLEGCRCDVGCKGRGDCCWDFEDTCVQSTQIWTCNKFRCGETRLESSLCSCSDDCLQRKDCCADYKSVCQGETSWVDEDCSTAQQPQCPEGFDLPPVILFSMDGFRAEYLQTWSTLVPNINKLKTCGVHSQYLRPAYPTKTFPNHYTIVTGLYPESHGIIDNNMYDINLNKNFSLSSKEKDNPAWWQGQPIWLTAMYQGLKVGTYFWPGSDVAINGTFPSIYKIYNRSVTYEERIFTLLKWLDLPKAERPDFYTIYVEEPDSQGHNYGPVSAGVIQALQLVDKTFGLLMEGLKQRNLVNCVNIILLADHGMDQTYCDKLEYMADYFSSINFYMFEGPAPRIRTRNIPQDFFTFNSEEIVRNLSCRKPDQHFKPYLSPDLPKRLHFAKNVRIDKVNLLVDRQWQAVRNRAYSYCGGGNHGYDNEFKSMEAIFLAHGPSFKQKTEVEPFDNIEVYNLLCDLLHIQPAPNNGTHGSLNHLLKVPFYEPSHAEELSKFSVCGFTVPLPTDTLGCSCSRLQTNSDLERVNQMLDLTQDEITATEKLNLPFGRPRLIQKNKEPCLLYHREYVSGFDKTLRMPLWSSYTVPKPGDTSPLPPTVPDCLRADVRVAPSESQNCSFSLADKNITHGFLYPPANNRTSNSQYDALITSNLVPMYEAFKTMWNYFHSVLLVKYAMERNGVNVVSGPVFDYDYDGHFDAPDEIADYAVNTSVPIPTHYFVVLTSCKNQSQTPDACTGWLDVLPFVIPHRPTNVESCPENKSESLWVEERFNVHTARVRDVELLTGLDFYQEKAQPVSEILQLKTYLPVFETVI |
cellular defense response cellular response to extracellular stimulus chemotaxis cytokine-mediated signaling pathway female pregnancy gene expression in utero embryonic development inflammatory response integrated stress response signaling learning negative regulation of cell population proliferation placenta blood vessel development positive regulation of apoptotic process positive regulation of cell cycle positive regulation of cell population proliferation positive regulation of DNA-templated transcription initiation positive regulation of miRNA transcription regulation of transcription by RNA polymerase II response to cAMP response to corticosterone response to gravity response to hydrogen peroxide response to mechanical stimulus response to progesterone response to virus response to wounding response to xenobiotic stimulus toll-like receptor signaling pathway vitellogenesis | chromatin; nucleoplasm; nucleus; presynaptic membrane; RNA polymerase II transcription regulator complex | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific promoter-specific chromatin binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Homo sapiens | Alternative splicing DNA-binding Nucleus Phosphoprotein Reference proteome | MFRDFGEPGP | MFRDFGEPGPSSGNGGGYGGPAQPPAAAQAAQQKFHLVPSINTMSGSQELQWMVQPHFLGPSSYPRPLTYPQYSPPQPRPGVIRALGPPPGVRRRPCEQISPEEEERRRVRRERNKLAAAKCRNRRKELTDFLQAETDKLEDEKSGLQREIEELQKQKERLELVLEAHRPICKIPEGAKEGDTGSTSGTSSPPAPCRPVPCISLSPGPVLEPEALHTPTLMTTPSLTPFTPSLVFTYPSTPEPCASAHRKSSSSSGDPSSDPLGSPTLLAL | cellular defense response cellular response to extracellular stimulus chemotaxis cytokine-mediated signaling pathway female pregnancy gene expression in utero embryonic development inflammatory response integrated stress response signaling learning negative regulation of cell population proliferation placenta blood vessel development positive regulation of apoptotic process positive regulation of cell cycle positive regulation of cell population proliferation positive regulation of DNA-templated transcription initiation positive regulation of miRNA transcription regulation of transcription by RNA polymerase II response to cAMP response to corticosterone response to gravity response to hydrogen peroxide response to mechanical stimulus response to progesterone response to virus response to wounding response to xenobiotic stimulus toll-like receptor signaling pathway vitellogenesis chromatin; nucleoplasm; nucleus; presynaptic membrane; RNA polymerase II transcription regulator complex DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific promoter-specific chromatin binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding Homo sapiens Alternative splicing DNA-binding Nucleus Phosphoprotein Reference proteome MFRDFGEPGP MFRDFGEPGPSSGNGGGYGGPAQPPAAAQAAQQKFHLVPSINTMSGSQELQWMVQPHFLGPSSYPRPLTYPQYSPPQPRPGVIRALGPPPGVRRRPCEQISPEEEERRRVRRERNKLAAAKCRNRRKELTDFLQAETDKLEDEKSGLQREIEELQKQKERLELVLEAHRPICKIPEGAKEGDTGSTSGTSSPPAPCRPVPCISLSPGPVLEPEALHTPTLMTTPSLTPFTPSLVFTYPSTPEPCASAHRKSSSSSGDPSSDPLGSPTLLAL |
absorption of visible light adaptation of rhodopsin mediated signaling cellular response to light stimulus detection of light stimulus detection of temperature stimulus involved in thermoception G protein-coupled receptor signaling pathway gene expression microtubule cytoskeleton organization photoreceptor cell maintenance phototransduction podosome assembly red, far-red light phototransduction response to light intensity response to light stimulus retina development in camera-type eye rhodopsin mediated signaling pathway rod bipolar cell differentiation sensory perception of light stimulus thermotaxis visual perception | cell-cell junction; Golgi apparatus; membrane; photoreceptor disc membrane; photoreceptor inner segment; photoreceptor inner segment membrane; photoreceptor outer segment; photoreceptor outer segment membrane; plasma membrane; rod photoreceptor outer segment; rough endoplasmic reticulum membrane; sperm head plasma membrane; sperm midpiece | 11-cis retinal binding G protein-coupled photoreceptor activity metal ion binding retinal binding spectrin binding | Mus musculus | Acetylation Cell projection Chromophore Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Metal-binding Palmitate Phosphoprotein Photoreceptor protein Receptor Reference proteome Retinal protein Sensory transduction Transducer Transmembrane Transmembrane helix Vision Zinc | MNGTEGPNFY | MNGTEGPNFYVPFSNVTGVVRSPFEQPQYYLAEPWQFSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVVFTWIMALACAAPPLVGWSRYIPEGMQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIFFLICWLPYASVAFYIFTHQGSNFGPIFMTLPAFFAKSSSIYNPVIYIMLNKQFRNCMLTTLCCGKNPLGDDDASATASKTETSQVAPA | absorption of visible light adaptation of rhodopsin mediated signaling cellular response to light stimulus detection of light stimulus detection of temperature stimulus involved in thermoception G protein-coupled receptor signaling pathway gene expression microtubule cytoskeleton organization photoreceptor cell maintenance phototransduction podosome assembly red, far-red light phototransduction response to light intensity response to light stimulus retina development in camera-type eye rhodopsin mediated signaling pathway rod bipolar cell differentiation sensory perception of light stimulus thermotaxis visual perception cell-cell junction; Golgi apparatus; membrane; photoreceptor disc membrane; photoreceptor inner segment; photoreceptor inner segment membrane; photoreceptor outer segment; photoreceptor outer segment membrane; plasma membrane; rod photoreceptor outer segment; rough endoplasmic reticulum membrane; sperm head plasma membrane; sperm midpiece 11-cis retinal binding G protein-coupled photoreceptor activity metal ion binding retinal binding spectrin binding Mus musculus Acetylation Cell projection Chromophore Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Metal-binding Palmitate Phosphoprotein Photoreceptor protein Receptor Reference proteome Retinal protein Sensory transduction Transducer Transmembrane Transmembrane helix Vision Zinc MNGTEGPNFY MNGTEGPNFYVPFSNVTGVVRSPFEQPQYYLAEPWQFSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVVFTWIMALACAAPPLVGWSRYIPEGMQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIFFLICWLPYASVAFYIFTHQGSNFGPIFMTLPAFFAKSSSIYNPVIYIMLNKQFRNCMLTTLCCGKNPLGDDDASATASKTETSQVAPA |
Group I intron splicing Group II intron splicing mitochondrial RNA processing mRNA processing regulation of translation RNA folding transcription elongation by mitochondrial RNA polymerase | mitochondrial matrix; mitochondrion | ATP binding ATP hydrolysis activity mRNA binding RNA binding RNA helicase activity RNA strand annealing activity | Saccharomyces cerevisiae | 3D-structure ATP-binding Helicase Hydrolase Mitochondrion mRNA processing mRNA splicing Nucleotide-binding Reference proteome RNA-binding Transit peptide Translation regulation | MLTSILIKGR | MLTSILIKGRTPVLASRNLLAALSNCNHITWAVSRRLYNDGNRDQRNFGRNQRNNNSNRYRNSRFNSRPRTRSREDDDEVHFDKTTFSKLIHVPKEDNSKEVTLDSLLEEGVLDKEIHKAITRMEFPGLTPVQQKTIKPILSSEDHDVIARAKTGTGKTFAFLIPIFQHLINTKFDSQYMVKAVIVAPTRDLALQIEAEVKKIHDMNYGLKKYACVSLVGGTDFRAAMNKMNKLRPNIVIATPGRLIDVLEKYSNKFFRFVDYKVLDEADRLLEIGFRDDLETISGILNEKNSKSADNIKTLLFSATLDDKVQKLANNIMNKKECLFLDTVDKNEPEAHERIDQSVVISEKFANSIFAAVEHIKKQIKERDSNYKAIIFAPTVKFTSFLCSILKNEFKKDLPILEFHGKITQNKRTSLVKRFKKDESGILVCTDVGARGMDFPNVHEVLQIGVPSELANYIHRIGRTARSGKEGSSVLFICKDELPFVRELEDAKNIVIAKQEKYEPSEEIKSEVLEAVTEEPEDISDIVISLISSYRSCIKEYRFSERRILPEIASTYGVLLNDPQLKIPVSRRFLDKLGLSRSPIGKAMFEIRDYSSRDGNNKSYDYDDDSEISFRGNKNYNNRSQNRDYDDEPFRRSNNNRRSFSRSNDKNNYSSRNSNIY | Group I intron splicing Group II intron splicing mitochondrial RNA processing mRNA processing regulation of translation RNA folding transcription elongation by mitochondrial RNA polymerase mitochondrial matrix; mitochondrion ATP binding ATP hydrolysis activity mRNA binding RNA binding RNA helicase activity RNA strand annealing activity Saccharomyces cerevisiae 3D-structure ATP-binding Helicase Hydrolase Mitochondrion mRNA processing mRNA splicing Nucleotide-binding Reference proteome RNA-binding Transit peptide Translation regulation MLTSILIKGR MLTSILIKGRTPVLASRNLLAALSNCNHITWAVSRRLYNDGNRDQRNFGRNQRNNNSNRYRNSRFNSRPRTRSREDDDEVHFDKTTFSKLIHVPKEDNSKEVTLDSLLEEGVLDKEIHKAITRMEFPGLTPVQQKTIKPILSSEDHDVIARAKTGTGKTFAFLIPIFQHLINTKFDSQYMVKAVIVAPTRDLALQIEAEVKKIHDMNYGLKKYACVSLVGGTDFRAAMNKMNKLRPNIVIATPGRLIDVLEKYSNKFFRFVDYKVLDEADRLLEIGFRDDLETISGILNEKNSKSADNIKTLLFSATLDDKVQKLANNIMNKKECLFLDTVDKNEPEAHERIDQSVVISEKFANSIFAAVEHIKKQIKERDSNYKAIIFAPTVKFTSFLCSILKNEFKKDLPILEFHGKITQNKRTSLVKRFKKDESGILVCTDVGARGMDFPNVHEVLQIGVPSELANYIHRIGRTARSGKEGSSVLFICKDELPFVRELEDAKNIVIAKQEKYEPSEEIKSEVLEAVTEEPEDISDIVISLISSYRSCIKEYRFSERRILPEIASTYGVLLNDPQLKIPVSRRFLDKLGLSRSPIGKAMFEIRDYSSRDGNNKSYDYDDDSEISFRGNKNYNNRSQNRDYDDEPFRRSNNNRRSFSRSNDKNNYSSRNSNIY |
de novo' protein folding intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress N-glycan processing protein deglycosylation protein folding rhodopsin biosynthetic process visual perception | cytoplasm; cytoplasmic vesicle; endoplasmic reticulum lumen; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; membrane | cyclosporin A binding peptidyl-prolyl cis-trans isomerase activity | Drosophila melanogaster | Glycoprotein Isomerase Membrane Reference proteome Rotamase Sensory transduction Signal Transmembrane Transmembrane helix Vision | MKSLLNRIIL | MKSLLNRIILCSAFLAVASGLSFTVTSRIYMDVKHNKKPVGRITFGLFGKLAPKTVANFRHICLRGINGTSYVGSRFHRVVDRFLVQGGDIVNGDGTGSISIYGDYFPDEDKALAVEHNRPGYLGMANRGPDTNGCQFYVTTVGAKWLDGKHTVFGKVLEGMDTIYAIEDVKTDTDDFPVEPVVISNCGEIPTEQFEFYPDDFNILGWIKAAGLPVTSSFCVLLIFHYFFRQLNMYC | de novo' protein folding intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress N-glycan processing protein deglycosylation protein folding rhodopsin biosynthetic process visual perception cytoplasm; cytoplasmic vesicle; endoplasmic reticulum lumen; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; membrane cyclosporin A binding peptidyl-prolyl cis-trans isomerase activity Drosophila melanogaster Glycoprotein Isomerase Membrane Reference proteome Rotamase Sensory transduction Signal Transmembrane Transmembrane helix Vision MKSLLNRIIL MKSLLNRIILCSAFLAVASGLSFTVTSRIYMDVKHNKKPVGRITFGLFGKLAPKTVANFRHICLRGINGTSYVGSRFHRVVDRFLVQGGDIVNGDGTGSISIYGDYFPDEDKALAVEHNRPGYLGMANRGPDTNGCQFYVTTVGAKWLDGKHTVFGKVLEGMDTIYAIEDVKTDTDDFPVEPVVISNCGEIPTEQFEFYPDDFNILGWIKAAGLPVTSSFCVLLIFHYFFRQLNMYC |
ductus arteriosus closure female pregnancy kidney development lipoxygenase pathway negative regulation of cell cycle ovulation parturition positive regulation of apoptotic process positive regulation of vascular associated smooth muscle cell proliferation prostaglandin metabolic process regulation of prostaglandin catabolic process response to estradiol response to ethanol response to lipopolysaccharide thrombin-activated receptor signaling pathway transforming growth factor beta receptor signaling pathway | basolateral plasma membrane; cytoplasm; cytosol; extracellular exosome; nucleoplasm | 15-hydroxyprostaglandin dehydrogenase (NAD+) activity identical protein binding NAD binding NAD+ binding oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor prostaglandin E receptor activity | Homo sapiens | 3D-structure Alternative splicing Cytoplasm Direct protein sequencing Disease variant Fatty acid metabolism Lipid metabolism NAD Oxidoreductase Prostaglandin metabolism Reference proteome Tumor suppressor | MHVNGKVALV | MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDALNGAIMKITTSKGIHFQDYDTTPFQAKTQ | ductus arteriosus closure female pregnancy kidney development lipoxygenase pathway negative regulation of cell cycle ovulation parturition positive regulation of apoptotic process positive regulation of vascular associated smooth muscle cell proliferation prostaglandin metabolic process regulation of prostaglandin catabolic process response to estradiol response to ethanol response to lipopolysaccharide thrombin-activated receptor signaling pathway transforming growth factor beta receptor signaling pathway basolateral plasma membrane; cytoplasm; cytosol; extracellular exosome; nucleoplasm 15-hydroxyprostaglandin dehydrogenase (NAD+) activity identical protein binding NAD binding NAD+ binding oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor prostaglandin E receptor activity Homo sapiens 3D-structure Alternative splicing Cytoplasm Direct protein sequencing Disease variant Fatty acid metabolism Lipid metabolism NAD Oxidoreductase Prostaglandin metabolism Reference proteome Tumor suppressor MHVNGKVALV MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDALNGAIMKITTSKGIHFQDYDTTPFQAKTQ |
canonical glycolysis glycolytic process response to xenobiotic stimulus skeletal muscle tissue regeneration | cytosol; membrane; phosphopyruvate hydratase complex | identical protein binding magnesium ion binding phosphopyruvate hydratase activity protein-containing complex binding | Rattus norvegicus | Acetylation Cytoplasm Direct protein sequencing Glycolysis Lyase Magnesium Metal-binding Phosphoprotein Reference proteome | MAMQKIFARE | MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGKGVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKVVIGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKAVFAGRKFRNPKAK | canonical glycolysis glycolytic process response to xenobiotic stimulus skeletal muscle tissue regeneration cytosol; membrane; phosphopyruvate hydratase complex identical protein binding magnesium ion binding phosphopyruvate hydratase activity protein-containing complex binding Rattus norvegicus Acetylation Cytoplasm Direct protein sequencing Glycolysis Lyase Magnesium Metal-binding Phosphoprotein Reference proteome MAMQKIFARE MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGKGVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKVVIGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKAVFAGRKFRNPKAK |
cellular response to histamine central nervous system neuron development chloride transmembrane transport chloride transport gamma-aminobutyric acid signaling pathway monoatomic ion transport ovulation cycle response to progesterone response to toxic substance | chloride channel complex; dendrite; GABA-A receptor complex; GABA-ergic synapse; neuron projection; nuclear envelope; plasma membrane; postsynaptic specialization membrane; presynaptic active zone membrane; receptor complex; Schaffer collateral - CA1 synapse; synapse | G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential GABA receptor binding GABA-A receptor activity GABA-gated chloride ion channel activity ligand-gated monoatomic ion channel activity ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential monoatomic anion channel activity neurotransmitter receptor activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | Rattus norvegicus | 3D-structure Cell membrane Chloride Chloride channel Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MWTVQNRESL | MWTVQNRESLGLLSFPVMVAMVCCAHSSNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFTTGAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFGKGPQKKGASKQDQSANEKNKLEMNKVQVDAHGNILLSTLEIRNETSGSEVLTGVSDPKATMYSYDSASIQYRKPLSSREGFGRGLDRHGVPGKGRIRRRASQLKVKIPDLTDVNSIDKWSRMFFPITFSLFNVVYWLYYVH | cellular response to histamine central nervous system neuron development chloride transmembrane transport chloride transport gamma-aminobutyric acid signaling pathway monoatomic ion transport ovulation cycle response to progesterone response to toxic substance chloride channel complex; dendrite; GABA-A receptor complex; GABA-ergic synapse; neuron projection; nuclear envelope; plasma membrane; postsynaptic specialization membrane; presynaptic active zone membrane; receptor complex; Schaffer collateral - CA1 synapse; synapse G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential GABA receptor binding GABA-A receptor activity GABA-gated chloride ion channel activity ligand-gated monoatomic ion channel activity ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential monoatomic anion channel activity neurotransmitter receptor activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential Rattus norvegicus 3D-structure Cell membrane Chloride Chloride channel Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport MWTVQNRESL MWTVQNRESLGLLSFPVMVAMVCCAHSSNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFTTGAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFGKGPQKKGASKQDQSANEKNKLEMNKVQVDAHGNILLSTLEIRNETSGSEVLTGVSDPKATMYSYDSASIQYRKPLSSREGFGRGLDRHGVPGKGRIRRRASQLKVKIPDLTDVNSIDKWSRMFFPITFSLFNVVYWLYYVH |
cellular detoxification of aldehyde fructosamine catabolic process gamma-aminobutyric acid biosynthetic process maintenance of lens transparency retinoid metabolic process retinol metabolic process | axon; cytosol; synapse | 3-deoxyglucosone dehydrogenase activity aldehyde dehydrogenase (NAD+) activity aminobutyraldehyde dehydrogenase activity benzaldehyde dehydrogenase (NAD+) activity glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity NAD binding retinal dehydrogenase activity | Equus caballus | Acetylation Cell projection Cytoplasm Direct protein sequencing Lipid metabolism NAD Oxidoreductase Phosphoprotein Reference proteome | MSSSGTPDLP | MSSSGTPDLPVLLTDLKFQYTKIFINNEWHDSVSGKKFPVFNPATEEKLCEVEEGDKEDVNKAVAAARQAFQIGSPWRTMDASERGRLLYKLADLVERDRLILATMESMNGGKLFSNAYLMDLGGCLKTLRYCAGWADKIQGRTIPSDGNFFTYTRHEPVGVCGQILPWNFPLLMFLWKIAPALSCGNTVVVKPAEQTPLSALHVATLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPFIVFADADLETALEVTHQALFYHQGQCCVAASRLFVEESIYDEFVRRSVERAKKYVLGNPLTPGVSQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFIQPTVFSNVSDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTTYGLFAGSFTKDLDKAITVSAALQAGTVWVNCYGVVSAQCPFGGFKMSGNGREMGEYGFHEYTEVKTVTVKISQKNS | cellular detoxification of aldehyde fructosamine catabolic process gamma-aminobutyric acid biosynthetic process maintenance of lens transparency retinoid metabolic process retinol metabolic process axon; cytosol; synapse 3-deoxyglucosone dehydrogenase activity aldehyde dehydrogenase (NAD+) activity aminobutyraldehyde dehydrogenase activity benzaldehyde dehydrogenase (NAD+) activity glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity NAD binding retinal dehydrogenase activity Equus caballus Acetylation Cell projection Cytoplasm Direct protein sequencing Lipid metabolism NAD Oxidoreductase Phosphoprotein Reference proteome MSSSGTPDLP MSSSGTPDLPVLLTDLKFQYTKIFINNEWHDSVSGKKFPVFNPATEEKLCEVEEGDKEDVNKAVAAARQAFQIGSPWRTMDASERGRLLYKLADLVERDRLILATMESMNGGKLFSNAYLMDLGGCLKTLRYCAGWADKIQGRTIPSDGNFFTYTRHEPVGVCGQILPWNFPLLMFLWKIAPALSCGNTVVVKPAEQTPLSALHVATLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPFIVFADADLETALEVTHQALFYHQGQCCVAASRLFVEESIYDEFVRRSVERAKKYVLGNPLTPGVSQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFIQPTVFSNVSDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTTYGLFAGSFTKDLDKAITVSAALQAGTVWVNCYGVVSAQCPFGGFKMSGNGREMGEYGFHEYTEVKTVTVKISQKNS |
arachidonic acid secretion lipid catabolic process phospholipid metabolic process | extracellular region | calcium ion binding phospholipase A2 activity | Naja naja | 3D-structure Calcium Direct protein sequencing Disulfide bond Hydrolase Lipid degradation Lipid metabolism Metal-binding Reference proteome Secreted | NLYQFKNMIK | NLYQFKNMIKCTVPSRSWWDFADYGCYCGRGGSGTPVDDLDRCCQVHDNCYNEAEKISGCWPYFKTYSYECSQGTLTCKGDNNACAASVCDCDRLAAICFAGAPYNDNNYNIDLKARCQ | arachidonic acid secretion lipid catabolic process phospholipid metabolic process extracellular region calcium ion binding phospholipase A2 activity Naja naja 3D-structure Calcium Direct protein sequencing Disulfide bond Hydrolase Lipid degradation Lipid metabolism Metal-binding Reference proteome Secreted NLYQFKNMIK NLYQFKNMIKCTVPSRSWWDFADYGCYCGRGGSGTPVDDLDRCCQVHDNCYNEAEKISGCWPYFKTYSYECSQGTLTCKGDNNACAASVCDCDRLAAICFAGAPYNDNNYNIDLKARCQ |
GDP biosynthetic process phosphorylation purine nucleotide metabolic process | cytoplasm; cytosol; nucleus | ATP binding guanylate kinase activity | Saccharomyces cerevisiae | 3D-structure Acetylation ATP-binding Direct protein sequencing Kinase Nucleotide-binding Phosphoprotein Reference proteome Transferase | MSRPIVISGP | MSRPIVISGPSGTGKSTLLKKLFAEYPDSFGFSVSSTTRTPRAGEVNGKDYNFVSVDEFKSMIKNNEFIEWAQFSGNYYGSTVASVKQVSKSGKTCILDIDMQGVKSVKAIPELNARFLFIAPPSVEDLKKRLEGRGTETEESINKRLSAAQAELAYAETGAHDKVIVNDDLDKAYKELKDFIFAEK | GDP biosynthetic process phosphorylation purine nucleotide metabolic process cytoplasm; cytosol; nucleus ATP binding guanylate kinase activity Saccharomyces cerevisiae 3D-structure Acetylation ATP-binding Direct protein sequencing Kinase Nucleotide-binding Phosphoprotein Reference proteome Transferase MSRPIVISGP MSRPIVISGPSGTGKSTLLKKLFAEYPDSFGFSVSSTTRTPRAGEVNGKDYNFVSVDEFKSMIKNNEFIEWAQFSGNYYGSTVASVKQVSKSGKTCILDIDMQGVKSVKAIPELNARFLFIAPPSVEDLKKRLEGRGTETEESINKRLSAAQAELAYAETGAHDKVIVNDDLDKAYKELKDFIFAEK |
cellular response to abscisic acid stimulus response to abscisic acid seed maturation | protein storage vacuole | nutrient reservoir activity | Arabidopsis thaliana | 3D-structure Alternative splicing Direct protein sequencing Disulfide bond Phosphoprotein Reference proteome Seed storage protein Signal Storage protein Vacuole | MARVSSLLSF | MARVSSLLSFCLTLLILFHGYAAQQGQQGQQFPNECQLDQLNALEPSHVLKSEAGRIEVWDHHAPQLRCSGVSFARYIIESKGLYLPSFFNTAKLSFVAKGRGLMGKVIPGCAETFQDSSEFQPRFEGQGQSQRFRDMHQKVEHIRSGDTIATTPGVAQWFYNDGQEPLVIVSVFDLASHQNQLDRNPRPFYLAGNNPQGQVWLQGREQQPQKNIFNGFGPEVIAQALKIDLQTAQQLQNQDDNRGNIVRVQGPFGVIRPPLRGQRPQEEEEEEGRHGRHGNGLEETICSARCTDNLDDPSRADVYKPQLGYISTLNSYDLPILRFIRLSALRGSIRQNAMVLPQWNANANAILYVTDGEAQIQIVNDNGNRVFDGQVSQGQLIAVPQGFSVVKRATSNRFQWVEFKTNANAQINTLAGRTSVLRGLPLEVITNGFQISPEEARRVKFNTLETTLTHSSGPASYGRPRVAAA | cellular response to abscisic acid stimulus response to abscisic acid seed maturation protein storage vacuole nutrient reservoir activity Arabidopsis thaliana 3D-structure Alternative splicing Direct protein sequencing Disulfide bond Phosphoprotein Reference proteome Seed storage protein Signal Storage protein Vacuole MARVSSLLSF MARVSSLLSFCLTLLILFHGYAAQQGQQGQQFPNECQLDQLNALEPSHVLKSEAGRIEVWDHHAPQLRCSGVSFARYIIESKGLYLPSFFNTAKLSFVAKGRGLMGKVIPGCAETFQDSSEFQPRFEGQGQSQRFRDMHQKVEHIRSGDTIATTPGVAQWFYNDGQEPLVIVSVFDLASHQNQLDRNPRPFYLAGNNPQGQVWLQGREQQPQKNIFNGFGPEVIAQALKIDLQTAQQLQNQDDNRGNIVRVQGPFGVIRPPLRGQRPQEEEEEEGRHGRHGNGLEETICSARCTDNLDDPSRADVYKPQLGYISTLNSYDLPILRFIRLSALRGSIRQNAMVLPQWNANANAILYVTDGEAQIQIVNDNGNRVFDGQVSQGQLIAVPQGFSVVKRATSNRFQWVEFKTNANAQINTLAGRTSVLRGLPLEVITNGFQISPEEARRVKFNTLETTLTHSSGPASYGRPRVAAA |
cellular response to abscisic acid stimulus response to abscisic acid seed maturation | protein storage vacuole | nutrient reservoir activity | Arabidopsis thaliana | Disulfide bond Phosphoprotein Reference proteome Seed storage protein Signal Storage protein Ubl conjugation Vacuole | MGRVSSIISF | MGRVSSIISFSLTLLILFNGYTAQQWPNECQLDQLNALEPSQIIKSEGGRIEVWDHHAPQLRCSGFAFERFVIEPQGLFLPTFLNAGKLTFVVHGRGLMGRVIPGCAETFMESPVFGEGQGQGQSQGFRDMHQKVEHLRCGDTIATPSGVAQWFYNNGNEPLILVAAADLASNQNQLDRNLRPFLIAGNNPQGQEWLQGRKQQKQNNIFNGFAPEILAQAFKINVETAQQLQNQQDNRGNIVKVNGPFGVIRPPLRRGEGGQQPHEIANGLEETLCTMRCTENLDDPSDADVYKPSLGYISTLNSYNLPILRLLRLSALRGSIRKNAMVLPQWNVNANAALYVTNGKAHIQMVNDNGERVFDQEISSGQLLVVPQGFSVMKHAIGEQFEWIEFKTNENAQVNTLAGRTSVMRGLPLEVITNGYQISPEEAKRVKFSTIETTLTHSSPMSYGRPRA | cellular response to abscisic acid stimulus response to abscisic acid seed maturation protein storage vacuole nutrient reservoir activity Arabidopsis thaliana Disulfide bond Phosphoprotein Reference proteome Seed storage protein Signal Storage protein Ubl conjugation Vacuole MGRVSSIISF MGRVSSIISFSLTLLILFNGYTAQQWPNECQLDQLNALEPSQIIKSEGGRIEVWDHHAPQLRCSGFAFERFVIEPQGLFLPTFLNAGKLTFVVHGRGLMGRVIPGCAETFMESPVFGEGQGQGQSQGFRDMHQKVEHLRCGDTIATPSGVAQWFYNNGNEPLILVAAADLASNQNQLDRNLRPFLIAGNNPQGQEWLQGRKQQKQNNIFNGFAPEILAQAFKINVETAQQLQNQQDNRGNIVKVNGPFGVIRPPLRRGEGGQQPHEIANGLEETLCTMRCTENLDDPSDADVYKPSLGYISTLNSYNLPILRLLRLSALRGSIRKNAMVLPQWNVNANAALYVTNGKAHIQMVNDNGERVFDQEISSGQLLVVPQGFSVMKHAIGEQFEWIEFKTNENAQVNTLAGRTSVMRGLPLEVITNGYQISPEEAKRVKFSTIETTLTHSSPMSYGRPRA |
proteolysis | host cell cytoplasm; T=13 icosahedral viral capsid | metal ion binding serine-type peptidase activity structural molecule activity | Avian infectious bursal disease virus | 3D-structure Capsid protein Direct protein sequencing Host cytoplasm Hydrolase Metal-binding Protease Serine protease T=13 icosahedral capsid protein Virion | MTNLQDQTQQ | MTNLQDQTQQIVPFIRSLLMPTTGPASIPDDTLEKHTLRSETSTYNLTVGDTGSGLIVFFPGFPGSIVGAHYTLQSNGNYKFDQMLLTAQNLPASYNYCRLVSRSLTVRSSTLPGGVYALNGTINAVTFQGSLSELTDVSYNGLMSATANINDKIGNVLVGEGVTVLSLPTSYDLGYVRLGDPIPAIGLDPKMVATCDSSDRPRVYTITAADDYQFSSQYQPGGVTITLFSANIDAITSLSVGGELVFQTSVHGLVLGATIYLIGFDGTTVITRAVAANNGLTTGTDNLMPFNLVISTNEITQPITSIKLEIVTSKSGGQAGDQMSWSAKGSLAVTIHGGNYPGALRPVTLVAYERVATGSVVTVAGVSNFELIPNPELAKNLVTEYGRFDPGAMNYTKLILSERDRLGIKTVWPTREYTDFREYFMEVADLNSPLKIAGAFGFKDIIRAIRRIAVPVVSTLFPPAAPLAHAIGEGVDYLLGDEAQAASGTARAASGKARAASGRIRQLTLAADKGYEVVANLFQVPQNPVVDGILASPGVLRGAHNLDCVLREGATLFPVVITTVEDAMTPKALNSKMFAVIEGVREDLQPPSQRGSFIRTLSGHRVYGYAPDGVLPLETGRDYTVVPIDDVWDDSIMLSKDPIPPIVGNSGNLAIAYMDVFRPKVPIHVAMTGALNACGEIEKVSFRSTKLATAHRLGLKLAGPGAFDVNTGPNWATFIKRFPHNPRDWDRLPYLNLPYLPPNAGRQYHLAMAASEFKETPELESAVRAMEAAANVDPLFQSALSVFMWLEENGIVTDMANFALSDPNAHRMRNFLANAPQAGSKSQRAKYGTAGYGVEARGPTPEEAQREKDTRISKKMETMGIYFATPEWVALNGHRGPSPGQLKYWQNTREIPDPNEDYLDYVHAEKSRLASEEQILRAATSIYGAPGQAEPPQAFIDEVAKVYEINHGRGPNQEQMKDLLLTAMEMKHRNPRRALPKPKPKPNAPTQRPPGRLGRWIRTVSDEDLE | proteolysis host cell cytoplasm; T=13 icosahedral viral capsid metal ion binding serine-type peptidase activity structural molecule activity Avian infectious bursal disease virus 3D-structure Capsid protein Direct protein sequencing Host cytoplasm Hydrolase Metal-binding Protease Serine protease T=13 icosahedral capsid protein Virion MTNLQDQTQQ MTNLQDQTQQIVPFIRSLLMPTTGPASIPDDTLEKHTLRSETSTYNLTVGDTGSGLIVFFPGFPGSIVGAHYTLQSNGNYKFDQMLLTAQNLPASYNYCRLVSRSLTVRSSTLPGGVYALNGTINAVTFQGSLSELTDVSYNGLMSATANINDKIGNVLVGEGVTVLSLPTSYDLGYVRLGDPIPAIGLDPKMVATCDSSDRPRVYTITAADDYQFSSQYQPGGVTITLFSANIDAITSLSVGGELVFQTSVHGLVLGATIYLIGFDGTTVITRAVAANNGLTTGTDNLMPFNLVISTNEITQPITSIKLEIVTSKSGGQAGDQMSWSAKGSLAVTIHGGNYPGALRPVTLVAYERVATGSVVTVAGVSNFELIPNPELAKNLVTEYGRFDPGAMNYTKLILSERDRLGIKTVWPTREYTDFREYFMEVADLNSPLKIAGAFGFKDIIRAIRRIAVPVVSTLFPPAAPLAHAIGEGVDYLLGDEAQAASGTARAASGKARAASGRIRQLTLAADKGYEVVANLFQVPQNPVVDGILASPGVLRGAHNLDCVLREGATLFPVVITTVEDAMTPKALNSKMFAVIEGVREDLQPPSQRGSFIRTLSGHRVYGYAPDGVLPLETGRDYTVVPIDDVWDDSIMLSKDPIPPIVGNSGNLAIAYMDVFRPKVPIHVAMTGALNACGEIEKVSFRSTKLATAHRLGLKLAGPGAFDVNTGPNWATFIKRFPHNPRDWDRLPYLNLPYLPPNAGRQYHLAMAASEFKETPELESAVRAMEAAANVDPLFQSALSVFMWLEENGIVTDMANFALSDPNAHRMRNFLANAPQAGSKSQRAKYGTAGYGVEARGPTPEEAQREKDTRISKKMETMGIYFATPEWVALNGHRGPSPGQLKYWQNTREIPDPNEDYLDYVHAEKSRLASEEQILRAATSIYGAPGQAEPPQAFIDEVAKVYEINHGRGPNQEQMKDLLLTAMEMKHRNPRRALPKPKPKPNAPTQRPPGRLGRWIRTVSDEDLE |
lipid catabolic process | extracellular region | metal ion binding triglyceride lipase activity | Vibrio cholerae serotype O1 | Calcium Disulfide bond Hydrolase Lipid degradation Lipid metabolism Metal-binding Reference proteome Secreted Signal | MNKIIILIAL | MNKIIILIALSLFSSSIWAGTSAHALSQQGYTQTRYPIVLVHGLFGFDTLAGMDYFHGIPQSLTRDGAQVYVAQVSATNSSERRGEQLLAQVESLLAVTGAKKVNLIGHSHGGPTIRYVASVRPDLVASVTSIGGVHKGSAVADLVRGVIPSGSVSEQVAVGLTQGLVALIDLLSGGKAHPQDPLASLAALTTEGSLKFNQYYPEGVPTSACGEGAYQVNGVRYYSWSGAATVTNILDPSDVAMGLIGLVFNEPNDGLVATCSTHLGKVIRDDYRMNHLDEINGLLGIHSLFETDPVTLYRQHANRLKQAGL | lipid catabolic process extracellular region metal ion binding triglyceride lipase activity Vibrio cholerae serotype O1 Calcium Disulfide bond Hydrolase Lipid degradation Lipid metabolism Metal-binding Reference proteome Secreted Signal MNKIIILIAL MNKIIILIALSLFSSSIWAGTSAHALSQQGYTQTRYPIVLVHGLFGFDTLAGMDYFHGIPQSLTRDGAQVYVAQVSATNSSERRGEQLLAQVESLLAVTGAKKVNLIGHSHGGPTIRYVASVRPDLVASVTSIGGVHKGSAVADLVRGVIPSGSVSEQVAVGLTQGLVALIDLLSGGKAHPQDPLASLAALTTEGSLKFNQYYPEGVPTSACGEGAYQVNGVRYYSWSGAATVTNILDPSDVAMGLIGLVFNEPNDGLVATCSTHLGKVIRDDYRMNHLDEINGLLGIHSLFETDPVTLYRQHANRLKQAGL |
dimethylallyl diphosphate biosynthetic process ergosterol biosynthetic process farnesyl diphosphate biosynthetic process isopentenyl diphosphate biosynthetic process | cytoplasm; cytosol; nucleus; vacuole | isopentenyl-diphosphate delta-isomerase activity metal ion binding | Saccharomyces cerevisiae | Cytoplasm Direct protein sequencing Isomerase Isoprene biosynthesis Lipid biosynthesis Lipid metabolism Magnesium Metal-binding Phosphoprotein Reference proteome Steroid biosynthesis Steroid metabolism Sterol biosynthesis Sterol metabolism | MTADNNSMPH | MTADNNSMPHGAVSSYAKLVQNQTPEDILEEFPEIIPLQQRPNTRSSETSNDESGETCFSGHDEEQIKLMNENCIVLDWDDNAIGAGTKKVCHLMENIEKGLLHRAFSVFIFNEQGELLLQQRATEKITFPDLWTNTCCSHPLCIDDELGLKGKLDDKIKGAITAAVRKLDHELGIPEDETKTRGKFHFLNRIHYMAPSNEPWGEHEIDYILFYKINAKENLTVNPNVNEVRDFKWVSPNDLKTMFADPSYKFTPWFKIICENYLFNWWEQLDDLSEVENDRQIHRML | dimethylallyl diphosphate biosynthetic process ergosterol biosynthetic process farnesyl diphosphate biosynthetic process isopentenyl diphosphate biosynthetic process cytoplasm; cytosol; nucleus; vacuole isopentenyl-diphosphate delta-isomerase activity metal ion binding Saccharomyces cerevisiae Cytoplasm Direct protein sequencing Isomerase Isoprene biosynthesis Lipid biosynthesis Lipid metabolism Magnesium Metal-binding Phosphoprotein Reference proteome Steroid biosynthesis Steroid metabolism Sterol biosynthesis Sterol metabolism MTADNNSMPH MTADNNSMPHGAVSSYAKLVQNQTPEDILEEFPEIIPLQQRPNTRSSETSNDESGETCFSGHDEEQIKLMNENCIVLDWDDNAIGAGTKKVCHLMENIEKGLLHRAFSVFIFNEQGELLLQQRATEKITFPDLWTNTCCSHPLCIDDELGLKGKLDDKIKGAITAAVRKLDHELGIPEDETKTRGKFHFLNRIHYMAPSNEPWGEHEIDYILFYKINAKENLTVNPNVNEVRDFKWVSPNDLKTMFADPSYKFTPWFKIICENYLFNWWEQLDDLSEVENDRQIHRML |
cholesterol metabolic process lipid transport lipoprotein metabolic process peptidyl-methionine modification phosphatidylcholine metabolic process positive regulation of cholesterol efflux positive regulation of phagocytosis positive regulation of phospholipid efflux protein oxidation protein stabilization regulation of intestinal cholesterol absorption | high-density lipoprotein particle | high-density lipoprotein particle receptor binding lipid binding protein homodimerization activity | Bos taurus | Cholesterol metabolism Direct protein sequencing Glycoprotein HDL Lipid metabolism Lipid transport Lipoprotein Oxidation Palmitate Phosphoprotein Reference proteome Repeat Secreted Signal Steroid metabolism Sterol metabolism Transport | MKAVVLTLAV | MKAVVLTLAVLFLTGSQARHFWQQDDPQSSWDRVKDFATVYVEAIKDSGRDYVAQFEASALGKQLNLKLLDNWDTLASTLSKVREQLGPVTQEFWDNLEKETASLRQEMHKDLEEVKQKVQPYLDEFQKKWHEEVEIYRQKVAPLGEEFREGARQKVQELQDKLSPLAQELRDRARAHVETLRQQLAPYSDDLRQRLTARLEALKEGGGSLAEYHAKASEQLKALGEKAKPVLEDLRQGLLPVLESLKVSILAAIDEASKKLNAQ | cholesterol metabolic process lipid transport lipoprotein metabolic process peptidyl-methionine modification phosphatidylcholine metabolic process positive regulation of cholesterol efflux positive regulation of phagocytosis positive regulation of phospholipid efflux protein oxidation protein stabilization regulation of intestinal cholesterol absorption high-density lipoprotein particle high-density lipoprotein particle receptor binding lipid binding protein homodimerization activity Bos taurus Cholesterol metabolism Direct protein sequencing Glycoprotein HDL Lipid metabolism Lipid transport Lipoprotein Oxidation Palmitate Phosphoprotein Reference proteome Repeat Secreted Signal Steroid metabolism Sterol metabolism Transport MKAVVLTLAV MKAVVLTLAVLFLTGSQARHFWQQDDPQSSWDRVKDFATVYVEAIKDSGRDYVAQFEASALGKQLNLKLLDNWDTLASTLSKVREQLGPVTQEFWDNLEKETASLRQEMHKDLEEVKQKVQPYLDEFQKKWHEEVEIYRQKVAPLGEEFREGARQKVQELQDKLSPLAQELRDRARAHVETLRQQLAPYSDDLRQRLTARLEALKEGGGSLAEYHAKASEQLKALGEKAKPVLEDLRQGLLPVLESLKVSILAAIDEASKKLNAQ |
cell migration cellular response to xenobiotic stimulus Fc-epsilon receptor signaling pathway Fc-gamma receptor signaling pathway involved in phagocytosis G protein-coupled receptor signaling pathway immune response integrin-mediated signaling pathway intracellular signal transduction neutrophil chemotaxis platelet activation positive regulation of natural killer cell mediated cytotoxicity reactive oxygen species metabolic process regulation of cell size regulation of GTPase activity regulation of small GTPase mediated signal transduction T cell costimulation T cell differentiation vascular endothelial growth factor receptor signaling pathway | cell-cell junction; cytoplasm; cytosol; plasma membrane | guanyl-nucleotide exchange factor activity metal ion binding phosphorylation-dependent protein binding phosphotyrosine residue binding | Homo sapiens | 3D-structure Alternative splicing Guanine-nucleotide releasing factor Metal-binding Phosphoprotein Proto-oncogene Reference proteome Repeat SH2 domain SH3 domain Zinc Zinc-finger | MELWRQCTHW | MELWRQCTHWLIQCRVLPPSHRVTWDGAQVCELAQALRDGVLLCQLLNNLLPHAINLREVNLRPQMSQFLCLKNIRTFLSTCCEKFGLKRSELFEAFDLFDVQDFGKVIYTLSALSWTPIAQNRGIMPFPTEEESVGDEDIYSGLSDQIDDTVEEDEDLYDCVENEEAEGDEIYEDLMRSEPVSMPPKMTEYDKRCCCLREIQQTEEKYTDTLGSIQQHFLKPLQRFLKPQDIEIIFINIEDLLRVHTHFLKEMKEALGTPGAANLYQVFIKYKERFLVYGRYCSQVESASKHLDRVAAAREDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQEAMEKENLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLAHYGRPKIDGELKITSVERRSKMDRYAFLLDKALLICKRRGDSYDLKDFVNLHSFQVRDDSSGDRDNKKWSHMFLLIEDQGAQGYELFFKTRELKKKWMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCHRCRASAHKECLGRVPPCGRHGQDFPGTMKKDKLHRRAQDKKRNELGLPKMEVFQEYYGLPPPPGAIGPFLRLNPGDIVELTKAEAEQNWWEGRNTSTNEIGWFPCNRVKPYVHGPPQDLSVHLWYAGPMERAGAESILANRSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKIMTAEGLYRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFPFKEPEKRTISRPAVGSTKYFGTAKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYGRVGWFPANYVEEDYSEYC | cell migration cellular response to xenobiotic stimulus Fc-epsilon receptor signaling pathway Fc-gamma receptor signaling pathway involved in phagocytosis G protein-coupled receptor signaling pathway immune response integrin-mediated signaling pathway intracellular signal transduction neutrophil chemotaxis platelet activation positive regulation of natural killer cell mediated cytotoxicity reactive oxygen species metabolic process regulation of cell size regulation of GTPase activity regulation of small GTPase mediated signal transduction T cell costimulation T cell differentiation vascular endothelial growth factor receptor signaling pathway cell-cell junction; cytoplasm; cytosol; plasma membrane guanyl-nucleotide exchange factor activity metal ion binding phosphorylation-dependent protein binding phosphotyrosine residue binding Homo sapiens 3D-structure Alternative splicing Guanine-nucleotide releasing factor Metal-binding Phosphoprotein Proto-oncogene Reference proteome Repeat SH2 domain SH3 domain Zinc Zinc-finger MELWRQCTHW MELWRQCTHWLIQCRVLPPSHRVTWDGAQVCELAQALRDGVLLCQLLNNLLPHAINLREVNLRPQMSQFLCLKNIRTFLSTCCEKFGLKRSELFEAFDLFDVQDFGKVIYTLSALSWTPIAQNRGIMPFPTEEESVGDEDIYSGLSDQIDDTVEEDEDLYDCVENEEAEGDEIYEDLMRSEPVSMPPKMTEYDKRCCCLREIQQTEEKYTDTLGSIQQHFLKPLQRFLKPQDIEIIFINIEDLLRVHTHFLKEMKEALGTPGAANLYQVFIKYKERFLVYGRYCSQVESASKHLDRVAAAREDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQEAMEKENLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLAHYGRPKIDGELKITSVERRSKMDRYAFLLDKALLICKRRGDSYDLKDFVNLHSFQVRDDSSGDRDNKKWSHMFLLIEDQGAQGYELFFKTRELKKKWMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCHRCRASAHKECLGRVPPCGRHGQDFPGTMKKDKLHRRAQDKKRNELGLPKMEVFQEYYGLPPPPGAIGPFLRLNPGDIVELTKAEAEQNWWEGRNTSTNEIGWFPCNRVKPYVHGPPQDLSVHLWYAGPMERAGAESILANRSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKIMTAEGLYRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFPFKEPEKRTISRPAVGSTKYFGTAKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYGRVGWFPANYVEEDYSEYC |
cell adhesion detection of light stimulus involved in visual perception photoreceptor cell outer segment organization protein heterooligomerization protein homooligomerization protein localization to plasma membrane protein maturation response to low light intensity stimulus retina development in camera-type eye | membrane; photoreceptor inner segment; photoreceptor outer segment | protein homodimerization activity | Mus musculus | Cell adhesion Cell projection Disulfide bond Glycoprotein Membrane Reference proteome Sensory transduction Transmembrane Transmembrane helix Vision | MALLKVKFDQ | MALLKVKFDQKKRVKLAQGLWLMNWLSVLAGIVLFSLGLFLKIELRKRSEVMNNSESHFVPNSLIGVGVLSCVFNSLAGKICYDALDPAKYAKWKPWLKPYLAVCIFFNVILFLVALCCFLLRGSLESTLAYGLKNGMKYYRDTDTPGRCFMKKTIDMLQIEFKCCGNNGFRDWFEIQWISNRYLDFSSKEVKDRIKSNVDGRYLVDGVPFSCCNPSSPRPCIQYQLTNNSAHYSYDHQTEELNLWLRGCRAALLNYYSSLMNSMGVVTLLVWLFEVSITAGLRYLHTALESVSNPEDPECESEGWLLEKSVPETWKAFLESFKKLGKSNQVEAEGADAGPAPEAG | cell adhesion detection of light stimulus involved in visual perception photoreceptor cell outer segment organization protein heterooligomerization protein homooligomerization protein localization to plasma membrane protein maturation response to low light intensity stimulus retina development in camera-type eye membrane; photoreceptor inner segment; photoreceptor outer segment protein homodimerization activity Mus musculus Cell adhesion Cell projection Disulfide bond Glycoprotein Membrane Reference proteome Sensory transduction Transmembrane Transmembrane helix Vision MALLKVKFDQ MALLKVKFDQKKRVKLAQGLWLMNWLSVLAGIVLFSLGLFLKIELRKRSEVMNNSESHFVPNSLIGVGVLSCVFNSLAGKICYDALDPAKYAKWKPWLKPYLAVCIFFNVILFLVALCCFLLRGSLESTLAYGLKNGMKYYRDTDTPGRCFMKKTIDMLQIEFKCCGNNGFRDWFEIQWISNRYLDFSSKEVKDRIKSNVDGRYLVDGVPFSCCNPSSPRPCIQYQLTNNSAHYSYDHQTEELNLWLRGCRAALLNYYSSLMNSMGVVTLLVWLFEVSITAGLRYLHTALESVSNPEDPECESEGWLLEKSVPETWKAFLESFKKLGKSNQVEAEGADAGPAPEAG |
animal organ morphogenesis aortic valve morphogenesis blood circulation extracellular matrix assembly outflow tract morphogenesis regulation of actin filament polymerization regulation of smooth muscle cell proliferation respiratory gaseous exchange by respiratory system skeletal muscle tissue development stress fiber assembly | collagen-containing extracellular matrix; elastic fiber; extracellular matrix; extracellular region | extracellular matrix binding extracellular matrix constituent conferring elasticity extracellular matrix structural constituent | Homo sapiens | Alternative splicing Disulfide bond Extracellular matrix Hydroxylation Reference proteome Repeat Secreted Signal Williams-Beuren syndrome | MAGLTAAAPR | MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGAAGAGVLGGLVPGAPGAVPGVPGTGGVPGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAGADEGVRRSLSPELREGDPSSSQHLPSTPSSPRVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKACGRKRK | animal organ morphogenesis aortic valve morphogenesis blood circulation extracellular matrix assembly outflow tract morphogenesis regulation of actin filament polymerization regulation of smooth muscle cell proliferation respiratory gaseous exchange by respiratory system skeletal muscle tissue development stress fiber assembly collagen-containing extracellular matrix; elastic fiber; extracellular matrix; extracellular region extracellular matrix binding extracellular matrix constituent conferring elasticity extracellular matrix structural constituent Homo sapiens Alternative splicing Disulfide bond Extracellular matrix Hydroxylation Reference proteome Repeat Secreted Signal Williams-Beuren syndrome MAGLTAAAPR MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGAAGAGVLGGLVPGAPGAVPGVPGTGGVPGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAGADEGVRRSLSPELREGDPSSSQHLPSTPSSPRVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKACGRKRK |
glycine catabolic process glycine decarboxylation via glycine cleavage system response to lipoic acid response to methylamine | glycine cleavage complex; mitochondrion | glycine binding glycine dehydrogenase (decarboxylating) activity glycine dehydrogenase activity lyase activity protein homodimerization activity pyridoxal binding pyridoxal phosphate binding | Gallus gallus | Direct protein sequencing Mitochondrion Oxidoreductase Pyridoxal phosphate Reference proteome Transit peptide | MQSCGRWWGR | MQSCGRWWGRLAARGAPRHLRPAAGGPRRQQQRWGGGEAARCIEQLLPRHDDFCRRHIGPREREKREMLSAVGVQSVEELMDKTIPASIRLRRPLRMDDHVVENEILETLYNIASKNKIWRSYIGMGYYNCSVPQPIARNLLENAGWVTQYTPYQPEVSQGRLESLLNYQTMVCDITGMDVANASLLDEGTAAAEAMQLCHRQNKRRKFYIDARCHPQTIANYTGVITELKLPHEMDFSGKDVSGVLFQYPDTEGKVEDFSELIERAHQNGTLACCATDLLALCILKPPGEFGVDVVLGSSQRFGVPLCYGGPHAAFFAVKENLVRMMPGRMVGVTRDANGKEVYRLALQTREQHIRRDKATSNICTAQALLANMAAMYGVYHGSDGLKDIARRVHNATLILAEGLRRAGHKLHHDLFFDTLTVTCGCSVKEVLDRAALRKINVRIYSDGRLGVSLDETVNEKDLDDILWIFGCESSAELVAEGMGEETKGILSTPFKRTSKFLTHQVFNSYHSETNIVRYMKRLENKDISLVHSMIPLGSCTMKLNSSAELAPISWKEFANIHPFVPLDQAQGYQQLFKDLEKDLCEITGYDKISFQPNSGAQGEYAGLAAIKAYLNAKGERHRSVCLIPRSAHGTNPASAQMAGMKIQPIEVDKNGSIDISHLKAMVDKHKENLAAIMITYPSTNGVFEEEIGDVCDLIHKHGGQVYLDGANMNAQVGLCRPGDYGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKKHLAPYLPTHPVIKIQTDKDACPLGTVSAAPWGSSAILPISWVYIKTMGAKGLKHASEIAILNANYMAKRLEKHYKILFRGVRGYVAHEFILDTRPFKKTANIEAVDLAKRLQDYGFHAPTMSWPVAGTLMIEPTESEDKGELDRFCDAMISIRQEIADIEEGRMDPQVNPLKMSPHTLNCVTSSKWDRPYSREVAAFPLPFVKPESKFWPTIARIDDIYGDQHLVCTCPPMEAYESPFSEQKRASS | glycine catabolic process glycine decarboxylation via glycine cleavage system response to lipoic acid response to methylamine glycine cleavage complex; mitochondrion glycine binding glycine dehydrogenase (decarboxylating) activity glycine dehydrogenase activity lyase activity protein homodimerization activity pyridoxal binding pyridoxal phosphate binding Gallus gallus Direct protein sequencing Mitochondrion Oxidoreductase Pyridoxal phosphate Reference proteome Transit peptide MQSCGRWWGR MQSCGRWWGRLAARGAPRHLRPAAGGPRRQQQRWGGGEAARCIEQLLPRHDDFCRRHIGPREREKREMLSAVGVQSVEELMDKTIPASIRLRRPLRMDDHVVENEILETLYNIASKNKIWRSYIGMGYYNCSVPQPIARNLLENAGWVTQYTPYQPEVSQGRLESLLNYQTMVCDITGMDVANASLLDEGTAAAEAMQLCHRQNKRRKFYIDARCHPQTIANYTGVITELKLPHEMDFSGKDVSGVLFQYPDTEGKVEDFSELIERAHQNGTLACCATDLLALCILKPPGEFGVDVVLGSSQRFGVPLCYGGPHAAFFAVKENLVRMMPGRMVGVTRDANGKEVYRLALQTREQHIRRDKATSNICTAQALLANMAAMYGVYHGSDGLKDIARRVHNATLILAEGLRRAGHKLHHDLFFDTLTVTCGCSVKEVLDRAALRKINVRIYSDGRLGVSLDETVNEKDLDDILWIFGCESSAELVAEGMGEETKGILSTPFKRTSKFLTHQVFNSYHSETNIVRYMKRLENKDISLVHSMIPLGSCTMKLNSSAELAPISWKEFANIHPFVPLDQAQGYQQLFKDLEKDLCEITGYDKISFQPNSGAQGEYAGLAAIKAYLNAKGERHRSVCLIPRSAHGTNPASAQMAGMKIQPIEVDKNGSIDISHLKAMVDKHKENLAAIMITYPSTNGVFEEEIGDVCDLIHKHGGQVYLDGANMNAQVGLCRPGDYGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKKHLAPYLPTHPVIKIQTDKDACPLGTVSAAPWGSSAILPISWVYIKTMGAKGLKHASEIAILNANYMAKRLEKHYKILFRGVRGYVAHEFILDTRPFKKTANIEAVDLAKRLQDYGFHAPTMSWPVAGTLMIEPTESEDKGELDRFCDAMISIRQEIADIEEGRMDPQVNPLKMSPHTLNCVTSSKWDRPYSREVAAFPLPFVKPESKFWPTIARIDDIYGDQHLVCTCPPMEAYESPFSEQKRASS |
cytokine-mediated signaling pathway granulocyte-macrophage colony-stimulating factor signaling pathway positive regulation of leukocyte proliferation receptor signaling pathway via JAK-STAT | external side of plasma membrane; extracellular region; granulocyte macrophage colony-stimulating factor receptor complex; plasma membrane; receptor complex | cytokine binding cytokine receptor activity signaling receptor activity | Homo sapiens | 3D-structure Alternative splicing Cell membrane Disease variant Disulfide bond Glycoprotein Membrane Receptor Reference proteome Secreted Signal Transmembrane Transmembrane helix | MLLLVTSLLL | MLLLVTSLLLCELPHPAFLLIPEKSDLRTVAPASSLNVRFDSRTMNLSWDCQENTTFSKCFLTDKKNRVVEPRLSNNECSCTFREICLHEGVTFEVHVNTSQRGFQQKLLYPNSGREGTAAQNFSCFIYNADLMNCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGCHLDNLSGLTSRNYFLVNGTSREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQLDVHRKNTQPGTENLLINVSGDLENRYNFPSSEPRAKHSVKIRAADVRILNWSSWSEAIEFGSDDGNLGSVYIYVLLIVGTLVCGIVLGFLFKRFLRIQRLFPPVPQIKDKLNDNHEVEDEIIWEEFTPEEGKGYREEVLTVKEIT | cytokine-mediated signaling pathway granulocyte-macrophage colony-stimulating factor signaling pathway positive regulation of leukocyte proliferation receptor signaling pathway via JAK-STAT external side of plasma membrane; extracellular region; granulocyte macrophage colony-stimulating factor receptor complex; plasma membrane; receptor complex cytokine binding cytokine receptor activity signaling receptor activity Homo sapiens 3D-structure Alternative splicing Cell membrane Disease variant Disulfide bond Glycoprotein Membrane Receptor Reference proteome Secreted Signal Transmembrane Transmembrane helix MLLLVTSLLL MLLLVTSLLLCELPHPAFLLIPEKSDLRTVAPASSLNVRFDSRTMNLSWDCQENTTFSKCFLTDKKNRVVEPRLSNNECSCTFREICLHEGVTFEVHVNTSQRGFQQKLLYPNSGREGTAAQNFSCFIYNADLMNCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGCHLDNLSGLTSRNYFLVNGTSREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQLDVHRKNTQPGTENLLINVSGDLENRYNFPSSEPRAKHSVKIRAADVRILNWSSWSEAIEFGSDDGNLGSVYIYVLLIVGTLVCGIVLGFLFKRFLRIQRLFPPVPQIKDKLNDNHEVEDEIIWEEFTPEEGKGYREEVLTVKEIT |
cell-cell signaling dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis epidermal growth factor receptor signaling pathway epithelial cell proliferation involved in mammary gland duct elongation ERBB2-EGFR signaling pathway G protein-coupled receptor signaling pathway glial cell proliferation mammary gland alveolus development mammary gland branching involved in thelarche negative regulation of osteoblast differentiation neuron projection development positive regulation of cell population proliferation positive regulation of keratinocyte proliferation positive regulation of peptidyl-tyrosine phosphorylation response to cAMP response to estradiol response to glucocorticoid response to hydrogen peroxide response to peptide hormone | cell surface; clathrin-coated endocytic vesicle membrane; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment membrane; ER to Golgi transport vesicle membrane; extracellular region; extracellular space; nucleus | cytokine activity epidermal growth factor receptor binding growth factor activity receptor ligand activity transmembrane receptor protein tyrosine kinase activator activity | Homo sapiens | 3D-structure Cytokine Direct protein sequencing Disulfide bond EGF-like domain Glycoprotein Growth factor Membrane Reference proteome Signal Transmembrane Transmembrane helix | MRAPLLPPAP | MRAPLLPPAPVVLSLLILGSGHYAAGLDLNDTYSGKREPFSGDHSADGFEVTSRSEMSSGSEISPVSEMPSSSEPSSGADYDYSEEYDNEPQIPGYIVDDSVRVEQVVKPPQNKTESENTSDKPKRKKKGGKNGKNRRNRKKKNPCNAEFQNFCIHGECKYIEHLEAVTCKCQQEYFGERCGEKSMKTHSMIDSSLSKIALAAIAAFMSAVILTAVAVITVQLRRQYVRKYEGEAEERKKLRQENGNVHAIA | cell-cell signaling dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis epidermal growth factor receptor signaling pathway epithelial cell proliferation involved in mammary gland duct elongation ERBB2-EGFR signaling pathway G protein-coupled receptor signaling pathway glial cell proliferation mammary gland alveolus development mammary gland branching involved in thelarche negative regulation of osteoblast differentiation neuron projection development positive regulation of cell population proliferation positive regulation of keratinocyte proliferation positive regulation of peptidyl-tyrosine phosphorylation response to cAMP response to estradiol response to glucocorticoid response to hydrogen peroxide response to peptide hormone cell surface; clathrin-coated endocytic vesicle membrane; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment membrane; ER to Golgi transport vesicle membrane; extracellular region; extracellular space; nucleus cytokine activity epidermal growth factor receptor binding growth factor activity receptor ligand activity transmembrane receptor protein tyrosine kinase activator activity Homo sapiens 3D-structure Cytokine Direct protein sequencing Disulfide bond EGF-like domain Glycoprotein Growth factor Membrane Reference proteome Signal Transmembrane Transmembrane helix MRAPLLPPAP MRAPLLPPAPVVLSLLILGSGHYAAGLDLNDTYSGKREPFSGDHSADGFEVTSRSEMSSGSEISPVSEMPSSSEPSSGADYDYSEEYDNEPQIPGYIVDDSVRVEQVVKPPQNKTESENTSDKPKRKKKGGKNGKNRRNRKKKNPCNAEFQNFCIHGECKYIEHLEAVTCKCQQEYFGERCGEKSMKTHSMIDSSLSKIALAAIAAFMSAVILTAVAVITVQLRRQYVRKYEGEAEERKKLRQENGNVHAIA |
biomineral tissue development defense response to bacterium defense response to fungus innate immune response killing of cells of another organism positive regulation of fibroblast proliferation positive regulation of wound healing | extracellular region; mitochondrion | metal ion binding molecular adaptor activity | Homo sapiens | Antibiotic Antimicrobial Biomineralization Cleavage on pair of basic residues Direct protein sequencing Fungicide Immunity Innate immunity Metal-binding Mitochondrion Reference proteome Secreted Signal Zinc | MKFFVFALIL | MKFFVFALILALMLSMTGADSHAKRHHGYKRKFHEKHHSHRGYRSNYLYDN | biomineral tissue development defense response to bacterium defense response to fungus innate immune response killing of cells of another organism positive regulation of fibroblast proliferation positive regulation of wound healing extracellular region; mitochondrion metal ion binding molecular adaptor activity Homo sapiens Antibiotic Antimicrobial Biomineralization Cleavage on pair of basic residues Direct protein sequencing Fungicide Immunity Innate immunity Metal-binding Mitochondrion Reference proteome Secreted Signal Zinc MKFFVFALIL MKFFVFALILALMLSMTGADSHAKRHHGYKRKFHEKHHSHRGYRSNYLYDN |
adaptive immune response complement activation, classical pathway innate immune response negative regulation of complement activation, classical pathway negative regulation of gene expression positive regulation of gene expression positive regulation of interleukin-10 production positive regulation of memory T cell differentiation positive regulation of regulatory T cell differentiation positive regulation of T cell proliferation positive regulation of transforming growth factor beta production regulation of Notch signaling pathway sequestering of extracellular ligand from receptor single fertilization T cell mediated immunity | cell surface; extracellular exosome; extracellular space; focal adhesion; inner acrosomal membrane; plasma membrane | cadherin binding signaling receptor activity virus receptor activity | Homo sapiens | 3D-structure Alternative splicing Complement pathway Cytoplasmic vesicle Direct protein sequencing Disease variant Disulfide bond Fertilization Glycoprotein Hemolytic uremic syndrome Host cell receptor for virus entry Host-virus interaction Immunity Innate immunity Membrane Phosphoprotein Receptor Reference proteome Repeat Signal Sushi Transmembrane Transmembrane helix | MEPPGRRECP | MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVLPPSSTKPPALSHSVSTSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKKGTYLTDETHREVKFTSL | adaptive immune response complement activation, classical pathway innate immune response negative regulation of complement activation, classical pathway negative regulation of gene expression positive regulation of gene expression positive regulation of interleukin-10 production positive regulation of memory T cell differentiation positive regulation of regulatory T cell differentiation positive regulation of T cell proliferation positive regulation of transforming growth factor beta production regulation of Notch signaling pathway sequestering of extracellular ligand from receptor single fertilization T cell mediated immunity cell surface; extracellular exosome; extracellular space; focal adhesion; inner acrosomal membrane; plasma membrane cadherin binding signaling receptor activity virus receptor activity Homo sapiens 3D-structure Alternative splicing Complement pathway Cytoplasmic vesicle Direct protein sequencing Disease variant Disulfide bond Fertilization Glycoprotein Hemolytic uremic syndrome Host cell receptor for virus entry Host-virus interaction Immunity Innate immunity Membrane Phosphoprotein Receptor Reference proteome Repeat Signal Sushi Transmembrane Transmembrane helix MEPPGRRECP MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVLPPSSTKPPALSHSVSTSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKKGTYLTDETHREVKFTSL |
adaptive immune response B cell differentiation B cell receptor signaling pathway response to bacterium | B cell receptor complex; external side of plasma membrane; IgM B cell receptor complex; plasma membrane | identical protein binding transmembrane signaling receptor activity | Mus musculus | 3D-structure Adaptive immunity Cell membrane Disulfide bond Glycoprotein Immunity Immunoglobulin domain Membrane Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix | MATLVLSSMP | MATLVLSSMPCHWLLFLLLLFSGEPVPAMTSSDLPLNFQGSPCSQIWQHPRFAAKKRSSMVKFHCYTNHSGALTWFRKRGSQQPQELVSEEGRIVQTQNGSVYTLTIQNIQYEDNGIYFCKQKCDSANHNVTDSCGTELLVLGFSTLDQLKRRNTLKDGIILIQTLLIILFIIVPIFLLLDKDDGKAGMEEDHTYEGLNIDQTATYEDIVTLRTGEVKWSVGEHPGQE | adaptive immune response B cell differentiation B cell receptor signaling pathway response to bacterium B cell receptor complex; external side of plasma membrane; IgM B cell receptor complex; plasma membrane identical protein binding transmembrane signaling receptor activity Mus musculus 3D-structure Adaptive immunity Cell membrane Disulfide bond Glycoprotein Immunity Immunoglobulin domain Membrane Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix MATLVLSSMP MATLVLSSMPCHWLLFLLLLFSGEPVPAMTSSDLPLNFQGSPCSQIWQHPRFAAKKRSSMVKFHCYTNHSGALTWFRKRGSQQPQELVSEEGRIVQTQNGSVYTLTIQNIQYEDNGIYFCKQKCDSANHNVTDSCGTELLVLGFSTLDQLKRRNTLKDGIILIQTLLIILFIIVPIFLLLDKDDGKAGMEEDHTYEGLNIDQTATYEDIVTLRTGEVKWSVGEHPGQE |
cell differentiation CTP biosynthetic process endocytosis GTP biosynthetic process lactation negative regulation of cell population proliferation nervous system development phosphorylation positive regulation of DNA binding positive regulation of epithelial cell proliferation regulation of apoptotic process UTP biosynthetic process | cytoplasm; cytosol; extracellular exosome; membrane; nucleus; ruffle membrane | 3'-5' exonuclease activity ATP binding DNA nuclease activity GTP binding identical protein binding magnesium ion binding nucleoside diphosphate kinase activity ribosomal small subunit binding RNA binding | Homo sapiens | 3D-structure Alternative splicing ATP-binding Cytoplasm Differentiation Direct protein sequencing Endocytosis Isopeptide bond Kinase Magnesium Metal-binding Neurogenesis Nucleotide metabolism Nucleotide-binding Nucleus Phosphoprotein Reference proteome Transferase Ubl conjugation | MANCERTFIA | MANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIGLWFHPEELVDYTSCAQNWIYE | cell differentiation CTP biosynthetic process endocytosis GTP biosynthetic process lactation negative regulation of cell population proliferation nervous system development phosphorylation positive regulation of DNA binding positive regulation of epithelial cell proliferation regulation of apoptotic process UTP biosynthetic process cytoplasm; cytosol; extracellular exosome; membrane; nucleus; ruffle membrane 3'-5' exonuclease activity ATP binding DNA nuclease activity GTP binding identical protein binding magnesium ion binding nucleoside diphosphate kinase activity ribosomal small subunit binding RNA binding Homo sapiens 3D-structure Alternative splicing ATP-binding Cytoplasm Differentiation Direct protein sequencing Endocytosis Isopeptide bond Kinase Magnesium Metal-binding Neurogenesis Nucleotide metabolism Nucleotide-binding Nucleus Phosphoprotein Reference proteome Transferase Ubl conjugation MANCERTFIA MANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIGLWFHPEELVDYTSCAQNWIYE |
cell differentiation CTP biosynthetic process dTMP biosynthetic process endocytosis GTP biosynthetic process lactation mammary gland development negative regulation of gene expression negative regulation of myeloid leukocyte differentiation nervous system development phosphorylation positive regulation of epithelial cell proliferation positive regulation of neuron projection development UTP biosynthetic process | centrosome; cytosol; mitochondrial outer membrane; mitochondrion; myelin sheath; nucleus; perinuclear region of cytoplasm; ruffle membrane | 3'-5' exonuclease activity ATP binding DNA nuclease activity enzyme binding gamma-tubulin binding GTP binding identical protein binding intermediate filament binding magnesium ion binding nucleoside diphosphate kinase activity protein kinase binding ribosomal small subunit binding RNA polymerase II transcription regulatory region sequence-specific DNA binding single-stranded DNA binding | Mus musculus | 3D-structure Acetylation ATP-binding Cytoplasm Differentiation Direct protein sequencing Endocytosis Isopeptide bond Kinase Magnesium Metal-binding Neurogenesis Nucleotide metabolism Nucleotide-binding Nucleus Phosphoprotein Reference proteome Transferase Ubl conjugation | MANSERTFIA | MANSERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFLQASEDLLKEHYTDLKDRPFFTGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVKSAEKEISLWFQPEELVEYKSCAQNWIYE | cell differentiation CTP biosynthetic process dTMP biosynthetic process endocytosis GTP biosynthetic process lactation mammary gland development negative regulation of gene expression negative regulation of myeloid leukocyte differentiation nervous system development phosphorylation positive regulation of epithelial cell proliferation positive regulation of neuron projection development UTP biosynthetic process centrosome; cytosol; mitochondrial outer membrane; mitochondrion; myelin sheath; nucleus; perinuclear region of cytoplasm; ruffle membrane 3'-5' exonuclease activity ATP binding DNA nuclease activity enzyme binding gamma-tubulin binding GTP binding identical protein binding intermediate filament binding magnesium ion binding nucleoside diphosphate kinase activity protein kinase binding ribosomal small subunit binding RNA polymerase II transcription regulatory region sequence-specific DNA binding single-stranded DNA binding Mus musculus 3D-structure Acetylation ATP-binding Cytoplasm Differentiation Direct protein sequencing Endocytosis Isopeptide bond Kinase Magnesium Metal-binding Neurogenesis Nucleotide metabolism Nucleotide-binding Nucleus Phosphoprotein Reference proteome Transferase Ubl conjugation MANSERTFIA MANSERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFLQASEDLLKEHYTDLKDRPFFTGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVKSAEKEISLWFQPEELVEYKSCAQNWIYE |
activation of innate immune response autophagy innate immune response negative regulation of interleukin-6 production negative regulation of NLRP3 inflammasome complex assembly negative regulation of reactive oxygen species metabolic process negative regulation of toll-like receptor signaling pathway negative regulation of tumor necrosis factor production negative regulation of viral entry into host cell positive regulation of autophagy positive regulation of canonical NF-kappaB signal transduction positive regulation of MAPK cascade positive regulation of protein catabolic process positive regulation of viral entry into host cell protein autoubiquitination protein K63-linked ubiquitination protein polyubiquitination regulation of lipopolysaccharide-mediated signaling pathway regulation of protein localization regulation of viral entry into host cell response to bacterium suppression of viral release by host | cytoplasm; cytosol; nucleoplasm; P-body | DNA binding identical protein binding pattern recognition receptor activity protein homodimerization activity protein kinase binding protein-macromolecule adaptor activity transcription coactivator activity ubiquitin protein ligase activity ubiquitin-protein transferase activity zinc ion binding | Mus musculus | 3D-structure Alternative splicing Coiled coil Cytoplasm DNA-binding Metal-binding Nucleus Reference proteome Transcription Transcription regulation Zinc Zinc-finger | MASSVLEMIK | MASSVLEMIKEEVTCPICLELLKEPVSADCNHSFCRACITLNYESNRNTDGKGNCPVCRVPYPFGNLRPNLHVANIVERLKGFKSIPEEEQKVNICAQHGEKLRLFCRKDMMVICWLCERSQEHRGHQTALIEEVDQEYKEKLQGALWKLMKKAKICDEWQDDLQLQRVDWENQIQINVENVQRQFKGLRDLLDSKENEELQKLKKEKKEVMEKLEESENELEDQTELVRDLISDVEHHLELSTLEMLQGANCVLRRSQSLSLQQPQTVPQKRKRTFQAPDLKGMLQVYQGLMDIQQYWVHMTLHARNNAVIAINKEKRQIQYRSYNTVPVSEIYHLGVLGYPALSSGKHYWEVDISRSDAWLLGLNDGKCAQPQLHSKEEMGIKKNLHSQIKQNVLFQPKCGYWVIGMKNPSVYKAFDECSITHNSSILVISLPDRPSRVGVFLDRKAGTLSFYDVSNCGALIYRFYDPAFPVEVYPYFNPMKCSEPMTICGPPS | activation of innate immune response autophagy innate immune response negative regulation of interleukin-6 production negative regulation of NLRP3 inflammasome complex assembly negative regulation of reactive oxygen species metabolic process negative regulation of toll-like receptor signaling pathway negative regulation of tumor necrosis factor production negative regulation of viral entry into host cell positive regulation of autophagy positive regulation of canonical NF-kappaB signal transduction positive regulation of MAPK cascade positive regulation of protein catabolic process positive regulation of viral entry into host cell protein autoubiquitination protein K63-linked ubiquitination protein polyubiquitination regulation of lipopolysaccharide-mediated signaling pathway regulation of protein localization regulation of viral entry into host cell response to bacterium suppression of viral release by host cytoplasm; cytosol; nucleoplasm; P-body DNA binding identical protein binding pattern recognition receptor activity protein homodimerization activity protein kinase binding protein-macromolecule adaptor activity transcription coactivator activity ubiquitin protein ligase activity ubiquitin-protein transferase activity zinc ion binding Mus musculus 3D-structure Alternative splicing Coiled coil Cytoplasm DNA-binding Metal-binding Nucleus Reference proteome Transcription Transcription regulation Zinc Zinc-finger MASSVLEMIK MASSVLEMIKEEVTCPICLELLKEPVSADCNHSFCRACITLNYESNRNTDGKGNCPVCRVPYPFGNLRPNLHVANIVERLKGFKSIPEEEQKVNICAQHGEKLRLFCRKDMMVICWLCERSQEHRGHQTALIEEVDQEYKEKLQGALWKLMKKAKICDEWQDDLQLQRVDWENQIQINVENVQRQFKGLRDLLDSKENEELQKLKKEKKEVMEKLEESENELEDQTELVRDLISDVEHHLELSTLEMLQGANCVLRRSQSLSLQQPQTVPQKRKRTFQAPDLKGMLQVYQGLMDIQQYWVHMTLHARNNAVIAINKEKRQIQYRSYNTVPVSEIYHLGVLGYPALSSGKHYWEVDISRSDAWLLGLNDGKCAQPQLHSKEEMGIKKNLHSQIKQNVLFQPKCGYWVIGMKNPSVYKAFDECSITHNSSILVISLPDRPSRVGVFLDRKAGTLSFYDVSNCGALIYRFYDPAFPVEVYPYFNPMKCSEPMTICGPPS |
acute inflammatory response angiogenesis involved in wound healing binding of sperm to zona pellucida cell adhesion cell population proliferation development of secondary sexual characteristics epithelial cell development epithelial cell proliferation extracellular matrix organization galactose metabolic process glycoprotein biosynthetic process lactose biosynthetic process lipid metabolic process macrophage migration negative regulation of epithelial cell proliferation oligosaccharide biosynthetic process penetration of zona pellucida positive regulation of apoptotic process positive regulation of circulating fibrinogen levels positive regulation of epithelial cell proliferation involved in wound healing protein glycosylation protein N-linked glycosylation regulation of acrosome reaction wound healing | basolateral plasma membrane; brush border membrane; cell surface; desmosome; external side of plasma membrane; extracellular region; filopodium; Golgi apparatus; Golgi cisterna membrane; Golgi trans cisterna; plasma membrane; protein-containing complex | alpha-tubulin binding beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity beta-tubulin binding cytoskeletal protein binding galactosyltransferase activity identical protein binding lactose synthase activity manganese ion binding N-acetyllactosamine synthase activity UDP-galactosyltransferase activity | Mus musculus | Alternative initiation Cell membrane Cell projection Disulfide bond Glycoprotein Glycosyltransferase Golgi apparatus Lipid metabolism Manganese Membrane Metal-binding Reference proteome Secreted Signal-anchor Transferase Transmembrane Transmembrane helix | MRFREQFLGG | MRFREQFLGGSAAMPGATLQRACRLLVAVCALHLGVTLVYYLSGRDLSRLPQLVGVSSTLQGGTNGAAASKQPPGEQRPRGARPPPPLGVSPKPRPGLDSSPGAASGPGLKSNLSSLPVPTTTGLLSLPACPEESPLLVGPMLIDFNIAVDLELLAKKNPEIKTGGRYSPKDCVSPHKVAIIIPFRNRQEHLKYWLYYLHPILQRQQLDYGIYVINQAGDTMFNRAKLLNIGFQEALKDYDYNCFVFSDVDLIPMDDRNAYRCFSQPRHISVAMDKFGFSLPYVQYFGGVSALSKQQFLAINGFPNNYWGWGGEDDDIFNRLVHKGMSISRPNAVVGRCRMIRHSRDKKNEPNPQRFDRIAHTKETMRFDGLNSLTYKVLDVQRYPLYTQITVDIGTPR | acute inflammatory response angiogenesis involved in wound healing binding of sperm to zona pellucida cell adhesion cell population proliferation development of secondary sexual characteristics epithelial cell development epithelial cell proliferation extracellular matrix organization galactose metabolic process glycoprotein biosynthetic process lactose biosynthetic process lipid metabolic process macrophage migration negative regulation of epithelial cell proliferation oligosaccharide biosynthetic process penetration of zona pellucida positive regulation of apoptotic process positive regulation of circulating fibrinogen levels positive regulation of epithelial cell proliferation involved in wound healing protein glycosylation protein N-linked glycosylation regulation of acrosome reaction wound healing basolateral plasma membrane; brush border membrane; cell surface; desmosome; external side of plasma membrane; extracellular region; filopodium; Golgi apparatus; Golgi cisterna membrane; Golgi trans cisterna; plasma membrane; protein-containing complex alpha-tubulin binding beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity beta-tubulin binding cytoskeletal protein binding galactosyltransferase activity identical protein binding lactose synthase activity manganese ion binding N-acetyllactosamine synthase activity UDP-galactosyltransferase activity Mus musculus Alternative initiation Cell membrane Cell projection Disulfide bond Glycoprotein Glycosyltransferase Golgi apparatus Lipid metabolism Manganese Membrane Metal-binding Reference proteome Secreted Signal-anchor Transferase Transmembrane Transmembrane helix MRFREQFLGG MRFREQFLGGSAAMPGATLQRACRLLVAVCALHLGVTLVYYLSGRDLSRLPQLVGVSSTLQGGTNGAAASKQPPGEQRPRGARPPPPLGVSPKPRPGLDSSPGAASGPGLKSNLSSLPVPTTTGLLSLPACPEESPLLVGPMLIDFNIAVDLELLAKKNPEIKTGGRYSPKDCVSPHKVAIIIPFRNRQEHLKYWLYYLHPILQRQQLDYGIYVINQAGDTMFNRAKLLNIGFQEALKDYDYNCFVFSDVDLIPMDDRNAYRCFSQPRHISVAMDKFGFSLPYVQYFGGVSALSKQQFLAINGFPNNYWGWGGEDDDIFNRLVHKGMSISRPNAVVGRCRMIRHSRDKKNEPNPQRFDRIAHTKETMRFDGLNSLTYKVLDVQRYPLYTQITVDIGTPR |
aldosterone biosynthetic process C21-steroid hormone biosynthetic process cellular response to hormone stimulus cellular response to peptide hormone stimulus cellular response to potassium ion cholesterol metabolic process cortisol biosynthetic process cortisol metabolic process glucocorticoid biosynthetic process glucose homeostasis immune response regulation of blood pressure sterol metabolic process | mitochondrial inner membrane; mitochondrion | corticosterone 18-monooxygenase activity heme binding iron ion binding steroid 11-beta-monooxygenase activity | Homo sapiens | 3D-structure Alternative splicing Congenital adrenal hyperplasia Direct protein sequencing Disease variant Heme Iron Lipid biosynthesis Lipid metabolism Membrane Metal-binding Mitochondrion Mitochondrion inner membrane Monooxygenase Oxidoreductase Reference proteome Steroid biosynthesis Steroidogenesis Transit peptide | MALRAKAEVC | MALRAKAEVCMAVPWLSLQRAQALGTRAARVPRTVLPFEAMPRRPGNRWLRLLQIWREQGYEDLHLEVHQTFQELGPIFRYDLGGAGMVCVMLPEDVEKLQQVDSLHPHRMSLEPWVAYRQHRGHKCGVFLLNGPEWRFNRLRLNPEVLSPNAVQRFLPMVDAVARDFSQALKKKVLQNARGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFMPRSLSRWTSPKVWKEHFEAWDCIFQYGDNCIQKIYQELAFSRPQQYTSIVAELLLNAELSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKATTELPLLRAALKETLRLYPVGLFLERVASSDLVLQNYHIPAGTLVRVFLYSLGRNPALFPRPERYNPQRWLDIRGSGRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQVETLTQEDIKMVYSFILRPSMFPLLTFRAIN | aldosterone biosynthetic process C21-steroid hormone biosynthetic process cellular response to hormone stimulus cellular response to peptide hormone stimulus cellular response to potassium ion cholesterol metabolic process cortisol biosynthetic process cortisol metabolic process glucocorticoid biosynthetic process glucose homeostasis immune response regulation of blood pressure sterol metabolic process mitochondrial inner membrane; mitochondrion corticosterone 18-monooxygenase activity heme binding iron ion binding steroid 11-beta-monooxygenase activity Homo sapiens 3D-structure Alternative splicing Congenital adrenal hyperplasia Direct protein sequencing Disease variant Heme Iron Lipid biosynthesis Lipid metabolism Membrane Metal-binding Mitochondrion Mitochondrion inner membrane Monooxygenase Oxidoreductase Reference proteome Steroid biosynthesis Steroidogenesis Transit peptide MALRAKAEVC MALRAKAEVCMAVPWLSLQRAQALGTRAARVPRTVLPFEAMPRRPGNRWLRLLQIWREQGYEDLHLEVHQTFQELGPIFRYDLGGAGMVCVMLPEDVEKLQQVDSLHPHRMSLEPWVAYRQHRGHKCGVFLLNGPEWRFNRLRLNPEVLSPNAVQRFLPMVDAVARDFSQALKKKVLQNARGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFMPRSLSRWTSPKVWKEHFEAWDCIFQYGDNCIQKIYQELAFSRPQQYTSIVAELLLNAELSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKATTELPLLRAALKETLRLYPVGLFLERVASSDLVLQNYHIPAGTLVRVFLYSLGRNPALFPRPERYNPQRWLDIRGSGRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQVETLTQEDIKMVYSFILRPSMFPLLTFRAIN |
aldosterone biosynthetic process cellular response to peptide hormone stimulus cholesterol metabolic process cortisol metabolic process drinking behavior glucocorticoid biosynthetic process monoatomic ion homeostasis regulation of blood volume by renal aldosterone regulation of systemic arterial blood pressure by circulatory renin-angiotensin | dendrite; mitochondrial inner membrane; mitochondrion | corticosterone 18-monooxygenase activity heme binding iron ion binding steroid 11-beta-monooxygenase activity | Mus musculus | Heme Iron Membrane Metal-binding Mitochondrion Mitochondrion inner membrane Monooxygenase Oxidoreductase Reference proteome Steroidogenesis Transit peptide | MALRVTADVW | MALRVTADVWLARPWQCLHRTRALGTTATLAPKTLQPFEAIPQYSRNKWLKMIQILREQGQENLHLEMHQVFRELGPIFRHSVGKTQIVSVMLPEDAEKLHQVESMLPRRMHLEPWVAHRELRGLRRGVFLLNGPEWRLNRLRLNRNVLSPKAVQKFVPMVDMVARDFLETLKEKVLQNARGSLTMDVQQSLFNYTIEASNFALFGERLGLLGHDLSPGSLKFIHALHSMFKSTSQLLFLPKSLTRWTSTRVWKEHFDAWDVISEYANRCIWKVHQELRLGSSQTYSGIVAELISQGSLPLDAIKANSMELTAGSVDTTAIPLVMTLFELARNPDVQKALRQESLAAEASIAANPQKAMSDLPLLRAALKETLRLYPVGGFLERILSSDLVLQNYHVPAGTLVLLYLYSMGRNPAVFPRPERYMPQRWLERKRSFQHLAFGFGVRQCLGRRLAEVEMMLLLHHILKTFQVETLRQEDVQMAYRFVLMPSSSPVLTFRPVS | aldosterone biosynthetic process cellular response to peptide hormone stimulus cholesterol metabolic process cortisol metabolic process drinking behavior glucocorticoid biosynthetic process monoatomic ion homeostasis regulation of blood volume by renal aldosterone regulation of systemic arterial blood pressure by circulatory renin-angiotensin dendrite; mitochondrial inner membrane; mitochondrion corticosterone 18-monooxygenase activity heme binding iron ion binding steroid 11-beta-monooxygenase activity Mus musculus Heme Iron Membrane Metal-binding Mitochondrion Mitochondrion inner membrane Monooxygenase Oxidoreductase Reference proteome Steroidogenesis Transit peptide MALRVTADVW MALRVTADVWLARPWQCLHRTRALGTTATLAPKTLQPFEAIPQYSRNKWLKMIQILREQGQENLHLEMHQVFRELGPIFRHSVGKTQIVSVMLPEDAEKLHQVESMLPRRMHLEPWVAHRELRGLRRGVFLLNGPEWRLNRLRLNRNVLSPKAVQKFVPMVDMVARDFLETLKEKVLQNARGSLTMDVQQSLFNYTIEASNFALFGERLGLLGHDLSPGSLKFIHALHSMFKSTSQLLFLPKSLTRWTSTRVWKEHFDAWDVISEYANRCIWKVHQELRLGSSQTYSGIVAELISQGSLPLDAIKANSMELTAGSVDTTAIPLVMTLFELARNPDVQKALRQESLAAEASIAANPQKAMSDLPLLRAALKETLRLYPVGGFLERILSSDLVLQNYHVPAGTLVLLYLYSMGRNPAVFPRPERYMPQRWLERKRSFQHLAFGFGVRQCLGRRLAEVEMMLLLHHILKTFQVETLRQEDVQMAYRFVLMPSSSPVLTFRPVS |
angiogenesis cell differentiation proteolysis | plasma membrane | aminopeptidase activity metallopeptidase activity zinc ion binding | Oryctolagus cuniculus | Aminopeptidase Angiogenesis Cell membrane Developmental protein Differentiation Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Membrane Metal-binding Metalloprotease Phosphoprotein Protease Reference proteome Signal-anchor Sulfation Transmembrane Transmembrane helix Zinc | MAKGFYISKS | MAKGFYISKSLGILGILLGVAALCTIVALSVVYRQEKNKNTSQSPSMAPLNPTATSSPATTLDQNLPWNRYRLPKTLIPDSYNVVLRPYLSPNSQGLYIFTGSSTVRFTCQEATNVIIIHSKKLNYTITQGHRVVLRGVRGSQPPAIASTELVELTEYLVVHLQGQLVAGSQYEMDTQFQGELADDLAGFYRSEYMEGNVRKVVATTQMQAADARKSFPCFDEPAMKATFNITPIHPRDYTALSNMLPRSSTALPEDPNWTVTEFHTTPKMSTYLLAYIVSEFTNIEAQSPNNVQIRIWARPSAISEGHGQYALNVTGPILNFFANHYNTPYPLEKSDQIGLPDFNAGAMENWGLVTYRESALLFDPLVSSISNKERVVTVVAHELAHQWFGNLVTVDWWNDLWLNEGFASYVEYLGADYAEPTWNLKDLIVLNELHSVMAVDALASSHPLSSPADEVNTPAQISELFDSITYSKGASVLRMLSSFLTEDLFKEGLASYLHTFAYQNTIYLDLWEHLQQAVNSQSAIQLPASVRDIMDRWILQMGFPVVTVNTTNGIISQHHFLLDPTSNVTRPSDFNYLWIVPVSSMRNGVLEQEFWLEGVEQTQNSLFRVEGDNNWILANLNVTGYYQVNYDEGNWKKLQTQLQTNPSVIPVINRAQIIHDAFNLASAQKVPVTLALDNTLFLIRETEYMPWQAALSSLNYFKLMFDRSEVYGPMKNYLSKQVRPLFEHFKNITNDWTRRPDTLMDQYNEINAISTACSNGIQECETLVSDLFKQWMDDPSNNPIHPNLRTTVYCNAIALGGEREWDFAWEQFRNATLVNEADKLRSALACSNEVWILNRYLSYTLNPDYIRRQDATSTINSIASNVIGQTLVWDFVQSNWKKLFEDFGGGSFSFANLIRAVTRRFSTEYELQQLEQFRLNNLDTGFGSGTRALEQALEQTRANIKWVQENKEAVLAWFTANSA | angiogenesis cell differentiation proteolysis plasma membrane aminopeptidase activity metallopeptidase activity zinc ion binding Oryctolagus cuniculus Aminopeptidase Angiogenesis Cell membrane Developmental protein Differentiation Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Membrane Metal-binding Metalloprotease Phosphoprotein Protease Reference proteome Signal-anchor Sulfation Transmembrane Transmembrane helix Zinc MAKGFYISKS MAKGFYISKSLGILGILLGVAALCTIVALSVVYRQEKNKNTSQSPSMAPLNPTATSSPATTLDQNLPWNRYRLPKTLIPDSYNVVLRPYLSPNSQGLYIFTGSSTVRFTCQEATNVIIIHSKKLNYTITQGHRVVLRGVRGSQPPAIASTELVELTEYLVVHLQGQLVAGSQYEMDTQFQGELADDLAGFYRSEYMEGNVRKVVATTQMQAADARKSFPCFDEPAMKATFNITPIHPRDYTALSNMLPRSSTALPEDPNWTVTEFHTTPKMSTYLLAYIVSEFTNIEAQSPNNVQIRIWARPSAISEGHGQYALNVTGPILNFFANHYNTPYPLEKSDQIGLPDFNAGAMENWGLVTYRESALLFDPLVSSISNKERVVTVVAHELAHQWFGNLVTVDWWNDLWLNEGFASYVEYLGADYAEPTWNLKDLIVLNELHSVMAVDALASSHPLSSPADEVNTPAQISELFDSITYSKGASVLRMLSSFLTEDLFKEGLASYLHTFAYQNTIYLDLWEHLQQAVNSQSAIQLPASVRDIMDRWILQMGFPVVTVNTTNGIISQHHFLLDPTSNVTRPSDFNYLWIVPVSSMRNGVLEQEFWLEGVEQTQNSLFRVEGDNNWILANLNVTGYYQVNYDEGNWKKLQTQLQTNPSVIPVINRAQIIHDAFNLASAQKVPVTLALDNTLFLIRETEYMPWQAALSSLNYFKLMFDRSEVYGPMKNYLSKQVRPLFEHFKNITNDWTRRPDTLMDQYNEINAISTACSNGIQECETLVSDLFKQWMDDPSNNPIHPNLRTTVYCNAIALGGEREWDFAWEQFRNATLVNEADKLRSALACSNEVWILNRYLSYTLNPDYIRRQDATSTINSIASNVIGQTLVWDFVQSNWKKLFEDFGGGSFSFANLIRAVTRRFSTEYELQQLEQFRLNNLDTGFGSGTRALEQALEQTRANIKWVQENKEAVLAWFTANSA |
tRNA methylation tRNA N2-guanine methylation | mitochondrion; nuclear envelope; nuclear inner membrane; nucleus | tRNA (guanine(10)-N2)-methyltransferase activity tRNA (guanine(26)-N2)-dimethyltransferase activity tRNA (guanine(26)-N2/guanine(27)-N2)-dimethyltransferase activity tRNA binding | Saccharomyces cerevisiae | Acetylation Alternative initiation Membrane Methyltransferase Mitochondrion Nucleus Reference proteome RNA-binding S-adenosyl-L-methionine Transferase Transit peptide tRNA processing tRNA-binding | MEGFFRIPLK | MEGFFRIPLKRANLHGMLKAAISKIKANFTAYGAPRINIEDFNIVKEGKAEILFPKKETVFYNPIQQFNRDLSVTCIKAWDNLYGEECGQKRNNKKSKKKRCAETNDDSSKRQKMGNGSPKEAVGNSNRNEPYINILEALSATGLRAIRYAHEIPHVREVIANDLLPEAVESIKRNVEYNSVENIVKPNLDDANVLMYRNKATNNKFHVIDLDPYGTVTPFVDAAIQSIEEGGLMLVTCTDLSVLAGNGYPEKCFALYGGANMVSHESTHESALRLVLNLLKQTAAKYKKTVEPLLSLSIDFYVRVFVKVKTSPIEVKNVMSSTMTTYHCSRCGSYHNQPLGRISQREGRNNKTFTKYSVAQGPPVDTKCKFCEGTYHLAGPMYAGPLHNKEFIEEVLRINKEEHRDQDDTYGTRKRIEGMLSLAKNELSDSPFYFSPNHIASVIKLQVPPLKKVVAGLGSLGFECSLTHAQPSSLKTNAPWDAIWYVMQKCDDEKKDLSKMNPNTTGYKILSAMPGWLSGTVKSEYDSKLSFAPNEQSGNIEKLRKLKIVRYQENPTKNWGPKARPNTS | tRNA methylation tRNA N2-guanine methylation mitochondrion; nuclear envelope; nuclear inner membrane; nucleus tRNA (guanine(10)-N2)-methyltransferase activity tRNA (guanine(26)-N2)-dimethyltransferase activity tRNA (guanine(26)-N2/guanine(27)-N2)-dimethyltransferase activity tRNA binding Saccharomyces cerevisiae Acetylation Alternative initiation Membrane Methyltransferase Mitochondrion Nucleus Reference proteome RNA-binding S-adenosyl-L-methionine Transferase Transit peptide tRNA processing tRNA-binding MEGFFRIPLK MEGFFRIPLKRANLHGMLKAAISKIKANFTAYGAPRINIEDFNIVKEGKAEILFPKKETVFYNPIQQFNRDLSVTCIKAWDNLYGEECGQKRNNKKSKKKRCAETNDDSSKRQKMGNGSPKEAVGNSNRNEPYINILEALSATGLRAIRYAHEIPHVREVIANDLLPEAVESIKRNVEYNSVENIVKPNLDDANVLMYRNKATNNKFHVIDLDPYGTVTPFVDAAIQSIEEGGLMLVTCTDLSVLAGNGYPEKCFALYGGANMVSHESTHESALRLVLNLLKQTAAKYKKTVEPLLSLSIDFYVRVFVKVKTSPIEVKNVMSSTMTTYHCSRCGSYHNQPLGRISQREGRNNKTFTKYSVAQGPPVDTKCKFCEGTYHLAGPMYAGPLHNKEFIEEVLRINKEEHRDQDDTYGTRKRIEGMLSLAKNELSDSPFYFSPNHIASVIKLQVPPLKKVVAGLGSLGFECSLTHAQPSSLKTNAPWDAIWYVMQKCDDEKKDLSKMNPNTTGYKILSAMPGWLSGTVKSEYDSKLSFAPNEQSGNIEKLRKLKIVRYQENPTKNWGPKARPNTS |
glycosaminoglycan catabolic process keratan sulfate catabolic process | azurophil granule lumen; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; lysosomal lumen | glycosaminoglycan binding metal ion binding N-acetylglucosamine-6-sulfatase activity sulfate binding sulfuric ester hydrolase activity | Homo sapiens | Alternative splicing Calcium Direct protein sequencing Disease variant Glycoprotein Hydrolase Lysosome Metal-binding Mucopolysaccharidosis Phosphoprotein Reference proteome Signal | MRLLPLAPGR | MRLLPLAPGRLRRGSPRHLPSCSPALLLLVLGGCLGVFGVAAGTRRPNVVLLLTDDQDEVLGGMTPLKKTKALIGEMGMTFSSAYVPSALCCPSRASILTGKYPHNHHVVNNTLEGNCSSKSWQKIQEPNTFPAILRSMCGYQTFFAGKYLNEYGAPDAGGLEHVPLGWSYWYALEKNSKYYNYTLSINGKARKHGENYSVDYLTDVLANVSLDFLDYKSNFEPFFMMIATPAPHSPWTAAPQYQKAFQNVFAPRNKNFNIHGTNKHWLIRQAKTPMTNSSIQFLDNAFRKRWQTLLSVDDLVEKLVKRLEFTGELNNTYIFYTSDNGYHTGQFSLPIDKRQLYEFDIKVPLLVRGPGIKPNQTSKMLVANIDLGPTILDIAGYDLNKTQMDGMSLLPILRGASNLTWRSDVLVEYQGEGRNVTDPTCPSLSPGVSQCFPDCVCEDAYNNTYACVRTMSALWNLQYCEFDDQEVFVEVYNLTADPDQITNIAKTIDPELLGKMNYRLMMLQSCSGPTCRTPGVFDPGYRFDPRLMFSNRGSVRTRRFSKHLL | glycosaminoglycan catabolic process keratan sulfate catabolic process azurophil granule lumen; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; lysosomal lumen glycosaminoglycan binding metal ion binding N-acetylglucosamine-6-sulfatase activity sulfate binding sulfuric ester hydrolase activity Homo sapiens Alternative splicing Calcium Direct protein sequencing Disease variant Glycoprotein Hydrolase Lysosome Metal-binding Mucopolysaccharidosis Phosphoprotein Reference proteome Signal MRLLPLAPGR MRLLPLAPGRLRRGSPRHLPSCSPALLLLVLGGCLGVFGVAAGTRRPNVVLLLTDDQDEVLGGMTPLKKTKALIGEMGMTFSSAYVPSALCCPSRASILTGKYPHNHHVVNNTLEGNCSSKSWQKIQEPNTFPAILRSMCGYQTFFAGKYLNEYGAPDAGGLEHVPLGWSYWYALEKNSKYYNYTLSINGKARKHGENYSVDYLTDVLANVSLDFLDYKSNFEPFFMMIATPAPHSPWTAAPQYQKAFQNVFAPRNKNFNIHGTNKHWLIRQAKTPMTNSSIQFLDNAFRKRWQTLLSVDDLVEKLVKRLEFTGELNNTYIFYTSDNGYHTGQFSLPIDKRQLYEFDIKVPLLVRGPGIKPNQTSKMLVANIDLGPTILDIAGYDLNKTQMDGMSLLPILRGASNLTWRSDVLVEYQGEGRNVTDPTCPSLSPGVSQCFPDCVCEDAYNNTYACVRTMSALWNLQYCEFDDQEVFVEVYNLTADPDQITNIAKTIDPELLGKMNYRLMMLQSCSGPTCRTPGVFDPGYRFDPRLMFSNRGSVRTRRFSKHLL |
female pregnancy learning or memory positive regulation of cell population proliferation response to estrogen response to organic cyclic compound response to peptide hormone response to pH skin development steroid metabolic process | endoplasmic reticulum membrane; nuclear envelope | arylsulfatase activity metal ion binding steryl-sulfatase activity sulfuric ester hydrolase activity | Rattus norvegicus | Calcium Direct protein sequencing Disulfide bond Endoplasmic reticulum Glycoprotein Hydrolase Lipid metabolism Membrane Metal-binding Microsome Pregnancy Reference proteome Signal Steroid metabolism Transmembrane Transmembrane helix | MLWPCLLALL | MLWPCLLALLLSQLNFLCAARPGPGPNFLLIMADDLGIGDLGCYGNRTLRTPHIDRLALEGVKLTQHLAAAPLCTPSRAAFLTGRYPVRSGMASHGRLGVFLFSASSGGLPPNEVTFAKLLKGQGYTTGLVGKWHLGLSCQAASDFCHHPGRHGFDRFLGTPTTNLRDCKPGGGTVFGSAQQVFVVLPMNILGAVLLAMALARWAGLARPPGWVFGVTVAAMAAVGGAYVAFLYHFRPANCFLMADFTITQQPTDYKGLTQRLASEAGDFLRRNRDTPFLLFLSFMHVHTAHFANPEFAGQSLHGAYGDAVEEMDWAVGQVLATLDKLGLANNTLVYLTSDHGAHVEELGPNGERHGGSNGIYRGGKANTWEGGIRVPGLVRWPGVIVPGQEVEEPTSNMDVFPTVARLAGAELPTDRVIDGRDLMPLLLGHVQHSEHEFLFHYCNAYLSAVAWRPHNSSSVWKAFYFTPNFDPPGSNGCFSTHVCMCHGHHVTHHDPPLLFDIARDPRERHPLTPETEPRHGEILRNMDAAARAHVATLEEAPNQLSMSNVAWKPWLQLCLPSKPHPLACRCAGDG | female pregnancy learning or memory positive regulation of cell population proliferation response to estrogen response to organic cyclic compound response to peptide hormone response to pH skin development steroid metabolic process endoplasmic reticulum membrane; nuclear envelope arylsulfatase activity metal ion binding steryl-sulfatase activity sulfuric ester hydrolase activity Rattus norvegicus Calcium Direct protein sequencing Disulfide bond Endoplasmic reticulum Glycoprotein Hydrolase Lipid metabolism Membrane Metal-binding Microsome Pregnancy Reference proteome Signal Steroid metabolism Transmembrane Transmembrane helix MLWPCLLALL MLWPCLLALLLSQLNFLCAARPGPGPNFLLIMADDLGIGDLGCYGNRTLRTPHIDRLALEGVKLTQHLAAAPLCTPSRAAFLTGRYPVRSGMASHGRLGVFLFSASSGGLPPNEVTFAKLLKGQGYTTGLVGKWHLGLSCQAASDFCHHPGRHGFDRFLGTPTTNLRDCKPGGGTVFGSAQQVFVVLPMNILGAVLLAMALARWAGLARPPGWVFGVTVAAMAAVGGAYVAFLYHFRPANCFLMADFTITQQPTDYKGLTQRLASEAGDFLRRNRDTPFLLFLSFMHVHTAHFANPEFAGQSLHGAYGDAVEEMDWAVGQVLATLDKLGLANNTLVYLTSDHGAHVEELGPNGERHGGSNGIYRGGKANTWEGGIRVPGLVRWPGVIVPGQEVEEPTSNMDVFPTVARLAGAELPTDRVIDGRDLMPLLLGHVQHSEHEFLFHYCNAYLSAVAWRPHNSSSVWKAFYFTPNFDPPGSNGCFSTHVCMCHGHHVTHHDPPLLFDIARDPRERHPLTPETEPRHGEILRNMDAAARAHVATLEEAPNQLSMSNVAWKPWLQLCLPSKPHPLACRCAGDG |
regulation of transcription by RNA polymerase II | nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific identical protein binding metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Homo sapiens | Alternative splicing DNA-binding Isopeptide bond Metal-binding Nucleus Reference proteome Repeat Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | MAAARLLPVP | MAAARLLPVPAGPQPLSFQAKLTFEDVAVLLSQDEWDRLCPAQRGLYRNVMMETYGNVVSLGLPGSKPDIISQLERGEDPWVLDRKGAKKSQGLWSDYSDNLKYDHTTACTQQDSLSCPWECETKGESQNTDLSPKPLISEQTVILGKTPLGRIDQENNETKQSFCLSPNSVDHREVQVLSQSMPLTPHQAVPSGERPYMCVECGKCFGRSSHLLQHQRIHTGEKPYVCSVCGKAFSQSSVLSKHRRIHTGEKPYECNECGKAFRVSSDLAQHHKIHTGEKPHECLECRKAFTQLSHLIQHQRIHTGERPYVCPLCGKAFNHSTVLRSHQRVHTGEKPHRCNECGKTFSVKRTLLQHQRIHTGEKPYTCSECGKAFSDRSVLIQHHNVHTGEKPYECSECGKTFSHRSTLMNHERIHTEEKPYACYECGKAFVQHSHLIQHQRVHTGEKPYVCGECGHAFSARRSLIQHERIHTGEKPFQCTECGKAFSLKATLIVHLRTHTGEKPYECNSCGKAFSQYSVLIQHQRIHTGEKPYECGECGRAFNQHGHLIQHQKVHRKL | regulation of transcription by RNA polymerase II nucleus DNA-binding transcription factor activity, RNA polymerase II-specific identical protein binding metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding Homo sapiens Alternative splicing DNA-binding Isopeptide bond Metal-binding Nucleus Reference proteome Repeat Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger MAAARLLPVP MAAARLLPVPAGPQPLSFQAKLTFEDVAVLLSQDEWDRLCPAQRGLYRNVMMETYGNVVSLGLPGSKPDIISQLERGEDPWVLDRKGAKKSQGLWSDYSDNLKYDHTTACTQQDSLSCPWECETKGESQNTDLSPKPLISEQTVILGKTPLGRIDQENNETKQSFCLSPNSVDHREVQVLSQSMPLTPHQAVPSGERPYMCVECGKCFGRSSHLLQHQRIHTGEKPYVCSVCGKAFSQSSVLSKHRRIHTGEKPYECNECGKAFRVSSDLAQHHKIHTGEKPHECLECRKAFTQLSHLIQHQRIHTGERPYVCPLCGKAFNHSTVLRSHQRVHTGEKPHRCNECGKTFSVKRTLLQHQRIHTGEKPYTCSECGKAFSDRSVLIQHHNVHTGEKPYECSECGKTFSHRSTLMNHERIHTEEKPYACYECGKAFVQHSHLIQHQRVHTGEKPYVCGECGHAFSARRSLIQHERIHTGEKPFQCTECGKAFSLKATLIVHLRTHTGEKPYECNSCGKAFSQYSVLIQHQRIHTGEKPYECGECGRAFNQHGHLIQHQKVHRKL |
phenylalanyl-tRNA aminoacylation | cytoplasm; phenylalanine-tRNA ligase complex | ATP binding magnesium ion binding phenylalanine-tRNA ligase activity RNA binding | Saccharomyces cerevisiae | Aminoacyl-tRNA synthetase ATP-binding Cytoplasm Direct protein sequencing Ligase Magnesium Metal-binding Nucleotide-binding Protein biosynthesis Reference proteome | MPTVSVNKQQ | MPTVSVNKQQLFDLLGKNYTSQEFDELCFEFGMEMDEDTTEEALKTGEEPELKLDISANRYDLLCIEGISQSLNEYLERKERPDYKLSKPTTKLIIDKSTEQIRPFATAAVLRNIKLNEKSYASFIALQDKLHANLCRNRSLVAMGTHDLDSIEGPFHYRALPPKDIKFVPLNQTQEFTGDKLIEFYKSPEQKNNIGRYVHIIEDSPVFPVIMDSKDRVCSLPPLINSEHSKISVNTRNILIDITATDKTKAEIVLNILTTMFSRYCDEPFTVEPVEIVSEHNGQSRLAPNFNDRIMDVSIKYINSCLGLDQSADEIAHCLKKMSLHAVQSKEDKDILHVDIPVTRPDILHACDIMEDAAVGYGFNNLPKGEKLSNANFIAKPLPINKVSDIFRVASSQATWVEVLPLTLCSHDENFKFLRQSDNGDLAVKLANPKTLEYQVVRTTLLPGILKTVKENRKHSLPIKVFETGDVVFKDDKLERKAYNERHWAAIYVGKNSGFEIIQGLLGKIMQTFRTEWIADYGAAASGRGYWIEEDDSVKTYFPGRGAKVMFRSKEGAEPKQIGHLGVLHPEVMMNFDVPFAASFVEVNAEVFL | phenylalanyl-tRNA aminoacylation cytoplasm; phenylalanine-tRNA ligase complex ATP binding magnesium ion binding phenylalanine-tRNA ligase activity RNA binding Saccharomyces cerevisiae Aminoacyl-tRNA synthetase ATP-binding Cytoplasm Direct protein sequencing Ligase Magnesium Metal-binding Nucleotide-binding Protein biosynthesis Reference proteome MPTVSVNKQQ MPTVSVNKQQLFDLLGKNYTSQEFDELCFEFGMEMDEDTTEEALKTGEEPELKLDISANRYDLLCIEGISQSLNEYLERKERPDYKLSKPTTKLIIDKSTEQIRPFATAAVLRNIKLNEKSYASFIALQDKLHANLCRNRSLVAMGTHDLDSIEGPFHYRALPPKDIKFVPLNQTQEFTGDKLIEFYKSPEQKNNIGRYVHIIEDSPVFPVIMDSKDRVCSLPPLINSEHSKISVNTRNILIDITATDKTKAEIVLNILTTMFSRYCDEPFTVEPVEIVSEHNGQSRLAPNFNDRIMDVSIKYINSCLGLDQSADEIAHCLKKMSLHAVQSKEDKDILHVDIPVTRPDILHACDIMEDAAVGYGFNNLPKGEKLSNANFIAKPLPINKVSDIFRVASSQATWVEVLPLTLCSHDENFKFLRQSDNGDLAVKLANPKTLEYQVVRTTLLPGILKTVKENRKHSLPIKVFETGDVVFKDDKLERKAYNERHWAAIYVGKNSGFEIIQGLLGKIMQTFRTEWIADYGAAASGRGYWIEEDDSVKTYFPGRGAKVMFRSKEGAEPKQIGHLGVLHPEVMMNFDVPFAASFVEVNAEVFL |
phenylalanyl-tRNA aminoacylation | cytoplasm; phenylalanine-tRNA ligase complex | aminoacyl-tRNA editing activity ATP binding magnesium ion binding phenylalanine-tRNA ligase activity tRNA binding | Saccharomyces cerevisiae | Acetylation Aminoacyl-tRNA synthetase ATP-binding Cytoplasm Direct protein sequencing Ligase Magnesium Metal-binding Nucleotide-binding Protein biosynthesis Reference proteome | MSDFQLEILK | MSDFQLEILKKLDELDEIKSTLATFPQHGSQDVLSALNSLKAHNKLEFSKVDTVTYDLTKEGAQILNEGSYEIKLVKLIQELGQLQIKDVMSKLGPQVGKVGQARAFKNGWIAKNASNELELSAKLQNTDLNELTDETQSILAQIKNNSHLDSIDAKILNDLKKRKLIAQGKITDFNVTKGPEFSTDLTKLETDLTSDMVSTNAYKDLKFKPYNFNSQGVQISSGALHPLNKVREEFRQIFFSMGFTEMPSNQYVETGFWNFDALYVPQQHPARDLQDTFYIKDPLTADLPDDKTYMDNIKAVHEQGRFGSIGYRYNWKPEECQKLVLRTHSTAISARMLHDLAKDPKPTRLFSIDRVFRNEAVDATHLAEFHQVEGVLADYNITLGDLIKFMEEFFERMGVTGLRFKPTYNPYTEPSMEIFSWHEGLQKWVEIGNSGMFRPEMLESMGLPKDLRVLGWGLSLERPTMIKYKVQNIRELLGHKVSLDFIETNPAARLDEDLYE | phenylalanyl-tRNA aminoacylation cytoplasm; phenylalanine-tRNA ligase complex aminoacyl-tRNA editing activity ATP binding magnesium ion binding phenylalanine-tRNA ligase activity tRNA binding Saccharomyces cerevisiae Acetylation Aminoacyl-tRNA synthetase ATP-binding Cytoplasm Direct protein sequencing Ligase Magnesium Metal-binding Nucleotide-binding Protein biosynthesis Reference proteome MSDFQLEILK MSDFQLEILKKLDELDEIKSTLATFPQHGSQDVLSALNSLKAHNKLEFSKVDTVTYDLTKEGAQILNEGSYEIKLVKLIQELGQLQIKDVMSKLGPQVGKVGQARAFKNGWIAKNASNELELSAKLQNTDLNELTDETQSILAQIKNNSHLDSIDAKILNDLKKRKLIAQGKITDFNVTKGPEFSTDLTKLETDLTSDMVSTNAYKDLKFKPYNFNSQGVQISSGALHPLNKVREEFRQIFFSMGFTEMPSNQYVETGFWNFDALYVPQQHPARDLQDTFYIKDPLTADLPDDKTYMDNIKAVHEQGRFGSIGYRYNWKPEECQKLVLRTHSTAISARMLHDLAKDPKPTRLFSIDRVFRNEAVDATHLAEFHQVEGVLADYNITLGDLIKFMEEFFERMGVTGLRFKPTYNPYTEPSMEIFSWHEGLQKWVEIGNSGMFRPEMLESMGLPKDLRVLGWGLSLERPTMIKYKVQNIRELLGHKVSLDFIETNPAARLDEDLYE |
glutathione metabolic process hepoxilin biosynthetic process xenobiotic catabolic process | cytoplasm; cytosol; intercellular bridge; protein-containing complex | enzyme binding glutathione binding glutathione transferase activity identical protein binding protein homodimerization activity | Mus musculus | Cytoplasm Direct protein sequencing Lipid metabolism Phosphoprotein Reference proteome Transferase | MPMTLGYWDI | MPMTLGYWDIRGLAHAIRLLLEYTDTSYEDKKYTMGDAPDYDRSQWLSEKFKLGLDFPNLPYLIDGSHKITQSNAILRYLARKHNLCGETEEERIRVDILENQAMDTRIQLAMVCYSPDFEKKKPEYLEGLPEKMKLYSEFLGKQPWFAGNKVTYVDFLVYDVLDQHRIFEPKCLDAFPNLKDFMGRFEGLKKISDYMKSSRFLSKPIFAKMAFWNPK | glutathione metabolic process hepoxilin biosynthetic process xenobiotic catabolic process cytoplasm; cytosol; intercellular bridge; protein-containing complex enzyme binding glutathione binding glutathione transferase activity identical protein binding protein homodimerization activity Mus musculus Cytoplasm Direct protein sequencing Lipid metabolism Phosphoprotein Reference proteome Transferase MPMTLGYWDI MPMTLGYWDIRGLAHAIRLLLEYTDTSYEDKKYTMGDAPDYDRSQWLSEKFKLGLDFPNLPYLIDGSHKITQSNAILRYLARKHNLCGETEEERIRVDILENQAMDTRIQLAMVCYSPDFEKKKPEYLEGLPEKMKLYSEFLGKQPWFAGNKVTYVDFLVYDVLDQHRIFEPKCLDAFPNLKDFMGRFEGLKKISDYMKSSRFLSKPIFAKMAFWNPK |
box C/D RNA 3'-end processing maturation of SSU-rRNA regulation of transcription by RNA polymerase I rRNA 2'-O-methylation rRNA methylation rRNA processing snoRNA guided rRNA 2'-O-methylation | 90S preribosome; box C/D RNP complex; nucleolus; nucleoplasm; small-subunit processome | histone H2AQ104 methyltransferase activity O-methyltransferase activity RNA binding rRNA methyltransferase activity | Saccharomyces cerevisiae | 3D-structure Direct protein sequencing Isopeptide bond Methylation Methyltransferase Nucleus Reference proteome Ribonucleoprotein Ribosome biogenesis RNA-binding rRNA processing S-adenosyl-L-methionine Transferase Ubl conjugation | MSFRPGSRGG | MSFRPGSRGGSRGGSRGGFGGRGGSRGGARGGSRGGFGGRGGSRGGARGGSRGGFGGRGGSRGGARGGSRGGRGGAAGGARGGAKVVIEPHRHAGVYIARGKEDLLVTKNMAPGESVYGEKRISVEEPSKEDGVPPTKVEYRVWNPFRSKLAAGIMGGLDELFIAPGKKVLYLGAASGTSVSHVSDVVGPEGVVYAVEFSHRPGRELISMAKKRPNIIPIIEDARHPQKYRMLIGMVDCVFADVAQPDQARIIALNSHMFLKDQGGVVISIKANCIDSTVDAETVFAREVQKLREERIKPLEQLTLEPYERDHCIVVGRYMRSGLKK | box C/D RNA 3'-end processing maturation of SSU-rRNA regulation of transcription by RNA polymerase I rRNA 2'-O-methylation rRNA methylation rRNA processing snoRNA guided rRNA 2'-O-methylation 90S preribosome; box C/D RNP complex; nucleolus; nucleoplasm; small-subunit processome histone H2AQ104 methyltransferase activity O-methyltransferase activity RNA binding rRNA methyltransferase activity Saccharomyces cerevisiae 3D-structure Direct protein sequencing Isopeptide bond Methylation Methyltransferase Nucleus Reference proteome Ribonucleoprotein Ribosome biogenesis RNA-binding rRNA processing S-adenosyl-L-methionine Transferase Ubl conjugation MSFRPGSRGG MSFRPGSRGGSRGGSRGGFGGRGGSRGGARGGSRGGFGGRGGSRGGARGGSRGGFGGRGGSRGGARGGSRGGRGGAAGGARGGAKVVIEPHRHAGVYIARGKEDLLVTKNMAPGESVYGEKRISVEEPSKEDGVPPTKVEYRVWNPFRSKLAAGIMGGLDELFIAPGKKVLYLGAASGTSVSHVSDVVGPEGVVYAVEFSHRPGRELISMAKKRPNIIPIIEDARHPQKYRMLIGMVDCVFADVAQPDQARIIALNSHMFLKDQGGVVISIKANCIDSTVDAETVFAREVQKLREERIKPLEQLTLEPYERDHCIVVGRYMRSGLKK |
carnitine catabolic process carnitine metabolic process, CoA-linked cellular lipid catabolic process fatty acid beta-oxidation using acyl-CoA dehydrogenase fatty acid catabolic process long-chain fatty acid catabolic process negative regulation of fatty acid biosynthetic process negative regulation of fatty acid oxidation positive regulation of cold-induced thermogenesis regulation of cholesterol metabolic process response to cold temperature homeostasis | cytoplasm; mitochondrial matrix; mitochondrial membrane; mitochondrion | fatty-acyl-CoA binding flavin adenine dinucleotide binding identical protein binding long-chain-acyl-CoA dehydrogenase activity palmitoyl-CoA oxidase activity | Rattus norvegicus | Acetylation Direct protein sequencing FAD Fatty acid metabolism Flavoprotein Lipid metabolism Mitochondrion Oxidoreductase Phosphoprotein Reference proteome Transit peptide | MAARLLLRSL | MAARLLLRSLRVLSARSATLPPPSARCSHSGAEARLETPSAKKLTDIGIRRIFSSEHDIFRESVRKFFQEEVIPYHEEWEKAGEVSRELWEKAGKQGLLGINIAEKHGGIGGDLLSTAVTWEEQAYSNCTGPGFSLHSDIVMPYIANYGTKEQIEQFIPQMTAGKCIGAIAMTEPGAGSDLQGVRTNAKRSGSDWILNGSKVFITNGWLSDLVIVVAVTNREARSPAHGISLFLVENGMKGFIKGKKLHKMGMKAQDTAELFFEDVRLPASALLGEENKGFYYLMQELPQERLLIADLAISACEFMFEETRNYVRQRKAFGKTVAHIQTVQHKLAELKTNICVTRAFVDSCLQLHETKRLDSASASMAKYWASELQNTVAYQCVQLHGGWGYMWEYPIAKAYVDARVQPIYGGTNEIMKELIARQIVSDS | carnitine catabolic process carnitine metabolic process, CoA-linked cellular lipid catabolic process fatty acid beta-oxidation using acyl-CoA dehydrogenase fatty acid catabolic process long-chain fatty acid catabolic process negative regulation of fatty acid biosynthetic process negative regulation of fatty acid oxidation positive regulation of cold-induced thermogenesis regulation of cholesterol metabolic process response to cold temperature homeostasis cytoplasm; mitochondrial matrix; mitochondrial membrane; mitochondrion fatty-acyl-CoA binding flavin adenine dinucleotide binding identical protein binding long-chain-acyl-CoA dehydrogenase activity palmitoyl-CoA oxidase activity Rattus norvegicus Acetylation Direct protein sequencing FAD Fatty acid metabolism Flavoprotein Lipid metabolism Mitochondrion Oxidoreductase Phosphoprotein Reference proteome Transit peptide MAARLLLRSL MAARLLLRSLRVLSARSATLPPPSARCSHSGAEARLETPSAKKLTDIGIRRIFSSEHDIFRESVRKFFQEEVIPYHEEWEKAGEVSRELWEKAGKQGLLGINIAEKHGGIGGDLLSTAVTWEEQAYSNCTGPGFSLHSDIVMPYIANYGTKEQIEQFIPQMTAGKCIGAIAMTEPGAGSDLQGVRTNAKRSGSDWILNGSKVFITNGWLSDLVIVVAVTNREARSPAHGISLFLVENGMKGFIKGKKLHKMGMKAQDTAELFFEDVRLPASALLGEENKGFYYLMQELPQERLLIADLAISACEFMFEETRNYVRQRKAFGKTVAHIQTVQHKLAELKTNICVTRAFVDSCLQLHETKRLDSASASMAKYWASELQNTVAYQCVQLHGGWGYMWEYPIAKAYVDARVQPIYGGTNEIMKELIARQIVSDS |
butyrate catabolic process fatty acid beta-oxidation fatty acid beta-oxidation using acyl-CoA dehydrogenase response to glucocorticoid response to starvation | mitochondrial matrix; mitochondrial membrane; mitochondrion | acyl-CoA dehydrogenase activity butyryl-CoA dehydrogenase activity fatty-acyl-CoA binding flavin adenine dinucleotide binding identical protein binding | Rattus norvegicus | 3D-structure Acetylation Direct protein sequencing FAD Fatty acid metabolism Flavoprotein Lipid metabolism Mitochondrion Oxidoreductase Phosphoprotein Reference proteome Transit peptide | MAAALLARAG | MAAALLARAGGSLGRALRARDWRRLHTVYQSVELPETHQMLRQTCRDFAEKELVPIAAQLDKEHLFPTSQVKKMGELGLLAMDVPEELSGAGLDYLAYSIALEEISRGCASTGVIMSVNNSLYLGPILKFGSSQQKQQWITPFTNGDKIGCFALSEPGNGSDAGAASTTAREEGDSWVLNGTKAWITNSWEASATVVFASTDRSRQNKGISAFLVPMPTPGLTLGKKEDKLGIRASSTANLIFEDCRIPKENLLGEPGMGFKIAMQTLDMGRIGIASQALGIAQASLDCAVKYAENRHAFGAPLTKLQNIQFKLADMALALESARLLTWRAAMLKDNKKPFTKESAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERYYRDARITEIYEGTSEIQRLVIAGHLLRSYRS | butyrate catabolic process fatty acid beta-oxidation fatty acid beta-oxidation using acyl-CoA dehydrogenase response to glucocorticoid response to starvation mitochondrial matrix; mitochondrial membrane; mitochondrion acyl-CoA dehydrogenase activity butyryl-CoA dehydrogenase activity fatty-acyl-CoA binding flavin adenine dinucleotide binding identical protein binding Rattus norvegicus 3D-structure Acetylation Direct protein sequencing FAD Fatty acid metabolism Flavoprotein Lipid metabolism Mitochondrion Oxidoreductase Phosphoprotein Reference proteome Transit peptide MAAALLARAG MAAALLARAGGSLGRALRARDWRRLHTVYQSVELPETHQMLRQTCRDFAEKELVPIAAQLDKEHLFPTSQVKKMGELGLLAMDVPEELSGAGLDYLAYSIALEEISRGCASTGVIMSVNNSLYLGPILKFGSSQQKQQWITPFTNGDKIGCFALSEPGNGSDAGAASTTAREEGDSWVLNGTKAWITNSWEASATVVFASTDRSRQNKGISAFLVPMPTPGLTLGKKEDKLGIRASSTANLIFEDCRIPKENLLGEPGMGFKIAMQTLDMGRIGIASQALGIAQASLDCAVKYAENRHAFGAPLTKLQNIQFKLADMALALESARLLTWRAAMLKDNKKPFTKESAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERYYRDARITEIYEGTSEIQRLVIAGHLLRSYRS |
animal organ morphogenesis cell differentiation fibroblast growth factor receptor signaling pathway glial cell differentiation positive regulation of cell division positive regulation of cell population proliferation positive regulation of gene expression positive regulation of protein phosphorylation regulation of cell migration signal transduction involved in regulation of gene expression | cytoplasm; extracellular space | fibroblast growth factor receptor binding growth factor activity | Mus musculus | Alternative splicing Glycoprotein Growth factor Mitogen Reference proteome Secreted Signal | MSLSLLFLIF | MSLSLLFLIFCSHLIHSAWAHGEKRLTPEGQPAPPRNPGDSSGSRGRSSATFSSSSASSPVAASPGSQGSGSEHSSFQWSPSGRRTGSLYCRVGIGFHLQIYPDGKVNGSHEASVLSILEIFAVSQGIVGIRGVFSNKFLAMSKKGKLHASAKFTDDCKFRERFQENSYNTYASAIHRTEKTGREWYVALNKRGKAKRGCSPRVKPQHVSTHFLPRFKQSEQPELSFTVTVPEKKKPPVKPKVPLSQPRRSPSPVKYRLKFRFG | animal organ morphogenesis cell differentiation fibroblast growth factor receptor signaling pathway glial cell differentiation positive regulation of cell division positive regulation of cell population proliferation positive regulation of gene expression positive regulation of protein phosphorylation regulation of cell migration signal transduction involved in regulation of gene expression cytoplasm; extracellular space fibroblast growth factor receptor binding growth factor activity Mus musculus Alternative splicing Glycoprotein Growth factor Mitogen Reference proteome Secreted Signal MSLSLLFLIF MSLSLLFLIFCSHLIHSAWAHGEKRLTPEGQPAPPRNPGDSSGSRGRSSATFSSSSASSPVAASPGSQGSGSEHSSFQWSPSGRRTGSLYCRVGIGFHLQIYPDGKVNGSHEASVLSILEIFAVSQGIVGIRGVFSNKFLAMSKKGKLHASAKFTDDCKFRERFQENSYNTYASAIHRTEKTGREWYVALNKRGKAKRGCSPRVKPQHVSTHFLPRFKQSEQPELSFTVTVPEKKKPPVKPKVPLSQPRRSPSPVKYRLKFRFG |
cap snatching DNA-templated transcription negative regulation of viral genome replication negative regulation of viral transcription negative stranded viral RNA replication protein import into nucleus suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity | host cell cytoplasm; host cell nucleus | endonuclease activity metal ion binding RNA binding RNA polymerase activity | Influenza A virus ) | 3D-structure Cap snatching Endonuclease Eukaryotic host gene expression shutoff by virus Eukaryotic host transcription shutoff by virus Host cytoplasm Host gene expression shutoff by virus Host nucleus Host-virus interaction Hydrolase Inhibition of host RNA polymerase II by virus Manganese Metal-binding Nuclease Phosphoprotein Reference proteome Ribosomal frameshifting | MEDFVRQCFN | MEDFVRQCFNPMIVELAEKAMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFIDEQGESIVVELGDPNALLKHRFEIIEGRDRTIAWTVINSICNTTGAEKPKFLPDLYDYKKNRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEETIEERFEITGTMRKLADQSLPPNFSSLENFRAYVDGFEPNGYIEGKLSQMSKEVNARIEPFLKSTPRPLRLPDGPPCSQRSKFLLMDALKLSIEDPSHEGEGIPLYDAIKCMRTFFGWKEPNVVKPHEKGINPNYLLSWKQVLAELQDIENEEKIPRTKNMKKTSQLKWALGENMAPEKVDFDDCKDVGDLKQYDSDEPELRSLASWIQNEFNKACELTDSSWIELDEIGEDAAPIEHIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEVGDMLLRSAIGHVSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENKSETWPVGESPKGVEEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLIVQALRDNLEPGTFDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALR | cap snatching DNA-templated transcription negative regulation of viral genome replication negative regulation of viral transcription negative stranded viral RNA replication protein import into nucleus suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity host cell cytoplasm; host cell nucleus endonuclease activity metal ion binding RNA binding RNA polymerase activity Influenza A virus )3D-structure Cap snatching Endonuclease Eukaryotic host gene expression shutoff by virus Eukaryotic host transcription shutoff by virus Host cytoplasm Host gene expression shutoff by virus Host nucleus Host-virus interaction Hydrolase Inhibition of host RNA polymerase II by virus Manganese Metal-binding Nuclease Phosphoprotein Reference proteome Ribosomal frameshifting MEDFVRQCFN MEDFVRQCFNPMIVELAEKAMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFIDEQGESIVVELGDPNALLKHRFEIIEGRDRTIAWTVINSICNTTGAEKPKFLPDLYDYKKNRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEETIEERFEITGTMRKLADQSLPPNFSSLENFRAYVDGFEPNGYIEGKLSQMSKEVNARIEPFLKSTPRPLRLPDGPPCSQRSKFLLMDALKLSIEDPSHEGEGIPLYDAIKCMRTFFGWKEPNVVKPHEKGINPNYLLSWKQVLAELQDIENEEKIPRTKNMKKTSQLKWALGENMAPEKVDFDDCKDVGDLKQYDSDEPELRSLASWIQNEFNKACELTDSSWIELDEIGEDAAPIEHIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEVGDMLLRSAIGHVSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENKSETWPVGESPKGVEEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLIVQALRDNLEPGTFDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALR |
angiogenesis cell differentiation metanephric proximal tubule development peptide catabolic process protein processing proteolysis | brush border membrane; cytoplasm; endoplasmic reticulum-Golgi intermediate compartment; external side of plasma membrane; extracellular exosome; extracellular space; plasma membrane | aminopeptidase activity metalloaminopeptidase activity peptide binding zinc ion binding | Rattus norvegicus | Aminopeptidase Angiogenesis Cell membrane Developmental protein Differentiation Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Membrane Metal-binding Metalloprotease Phosphoprotein Protease Reference proteome Signal-anchor Sulfation Transmembrane Transmembrane helix Zinc | MAKGFYISKT | MAKGFYISKTLGILGILLGVAAVCTIIALSVVYAQEKNRNAENSAIAPTLPGSTSATTSTTNPAIDESKPWNQYRLPKTLIPDSYQVTLRPYLTPNEQGLYIFKGSSTVRFTCNETTNVIIIHSKKLNYTNKGNHRVALRALGDTPAPNIDTTELVERTEYLVVHLQGSLVKGHQYEMDSEFQGELADDLAGFYRSEYMEGGNKKVVATTQMQAADARKSFPCFDEPAMKASFNITLIHPNNLTALSNMLPKDSRTLQEDPSWNVTEFHPTPKMSTYLLAYIVSEFKYVEAVSPNRVQIRIWARPSAIDEGHGDYALQVTGPILNFFAQHYNTAYPLEKSDQIALPDFNAGAMENWGLVTYRESALVFDPQSSSISNKERVVTVIAHELAHQWFGNLVTVDWWNDLWLNEGFASYVEFLGADYAEPTWNLKDLIVLNDVYRVMAVDALASSHPLSSPANEVNTPAQISELFDSITYSKGASVLRMLSSFLTEDLFKKGLSSYLHTFQYSNTIYLDLWEHLQQAVDSQTAIKLPASVSTIMDRWILQMGFPVITVNTSTGEIYQEHFLLDPTSKPTRPSDFNYLWIVPIPYLKNGKEDHYWLETEKNQSAEFQTSSNEWLLLNINVTGYYQVNYDENNWRKIQNQLQTDLSVIPVINRAQIIHDSFNLASAGKLSITLPLSNTLFLASETEYMPWEAALSSLNYFKLMFDRSEVYGPMKRYLKKQVTPLFAYFKIKTNNWLDRPPTLMEQYNEINAISTACSSGLEECRDLVVGLYSQWMNNSDNNPIHPNLRSTVYCNAIAFGGEEEWNFAWEQFRKATLVNEADKLRSALACSNEVWILNRYLSYTLNPDYIRKQDATSTIVSIANNVVGQTLVWDFVRSNWKKLFEDYGGGSFSFANLIQGVTRRFSSEFELQQLEQFKEDNSATGFGSGTRALEQALEKTKANIKWVKENKDVVLKWFTENS | angiogenesis cell differentiation metanephric proximal tubule development peptide catabolic process protein processing proteolysis brush border membrane; cytoplasm; endoplasmic reticulum-Golgi intermediate compartment; external side of plasma membrane; extracellular exosome; extracellular space; plasma membrane aminopeptidase activity metalloaminopeptidase activity peptide binding zinc ion binding Rattus norvegicus Aminopeptidase Angiogenesis Cell membrane Developmental protein Differentiation Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Membrane Metal-binding Metalloprotease Phosphoprotein Protease Reference proteome Signal-anchor Sulfation Transmembrane Transmembrane helix Zinc MAKGFYISKT MAKGFYISKTLGILGILLGVAAVCTIIALSVVYAQEKNRNAENSAIAPTLPGSTSATTSTTNPAIDESKPWNQYRLPKTLIPDSYQVTLRPYLTPNEQGLYIFKGSSTVRFTCNETTNVIIIHSKKLNYTNKGNHRVALRALGDTPAPNIDTTELVERTEYLVVHLQGSLVKGHQYEMDSEFQGELADDLAGFYRSEYMEGGNKKVVATTQMQAADARKSFPCFDEPAMKASFNITLIHPNNLTALSNMLPKDSRTLQEDPSWNVTEFHPTPKMSTYLLAYIVSEFKYVEAVSPNRVQIRIWARPSAIDEGHGDYALQVTGPILNFFAQHYNTAYPLEKSDQIALPDFNAGAMENWGLVTYRESALVFDPQSSSISNKERVVTVIAHELAHQWFGNLVTVDWWNDLWLNEGFASYVEFLGADYAEPTWNLKDLIVLNDVYRVMAVDALASSHPLSSPANEVNTPAQISELFDSITYSKGASVLRMLSSFLTEDLFKKGLSSYLHTFQYSNTIYLDLWEHLQQAVDSQTAIKLPASVSTIMDRWILQMGFPVITVNTSTGEIYQEHFLLDPTSKPTRPSDFNYLWIVPIPYLKNGKEDHYWLETEKNQSAEFQTSSNEWLLLNINVTGYYQVNYDENNWRKIQNQLQTDLSVIPVINRAQIIHDSFNLASAGKLSITLPLSNTLFLASETEYMPWEAALSSLNYFKLMFDRSEVYGPMKRYLKKQVTPLFAYFKIKTNNWLDRPPTLMEQYNEINAISTACSSGLEECRDLVVGLYSQWMNNSDNNPIHPNLRSTVYCNAIAFGGEEEWNFAWEQFRKATLVNEADKLRSALACSNEVWILNRYLSYTLNPDYIRKQDATSTIVSIANNVVGQTLVWDFVRSNWKKLFEDYGGGSFSFANLIQGVTRRFSSEFELQQLEQFKEDNSATGFGSGTRALEQALEKTKANIKWVKENKDVVLKWFTENS |
cellular response to BMP stimulus dephosphorylation | external side of plasma membrane; plasma membrane | alkaline phosphatase activity magnesium ion binding protease binding protein homodimerization activity zinc ion binding | Rattus norvegicus | 3D-structure Calcium Cell membrane Direct protein sequencing Disulfide bond Glycoprotein GPI-anchor Hydrolase Lipoprotein Magnesium Membrane Metal-binding Reference proteome Signal Zinc | MQGDWVLLLL | MQGDWVLLLLLGLRIHLSFGVIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSHVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPADENRPTTPVQNSAITMNNVLLSLQLLVSMLLLVGTALVVS | cellular response to BMP stimulus dephosphorylation external side of plasma membrane; plasma membrane alkaline phosphatase activity magnesium ion binding protease binding protein homodimerization activity zinc ion binding Rattus norvegicus 3D-structure Calcium Cell membrane Direct protein sequencing Disulfide bond Glycoprotein GPI-anchor Hydrolase Lipoprotein Magnesium Membrane Metal-binding Reference proteome Signal Zinc MQGDWVLLLL MQGDWVLLLLLGLRIHLSFGVIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSHVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPADENRPTTPVQNSAITMNNVLLSLQLLVSMLLLVGTALVVS |
adaptive immune response B cell differentiation B cell proliferation cytokine-mediated signaling pathway defense response to virus female pregnancy humoral immune response natural killer cell activation involved in immune response positive regulation of cellular biosynthetic process positive regulation of peptidyl-serine phosphorylation of STAT protein response to exogenous dsRNA T cell activation involved in immune response | extracellular space | cytokine activity hormone activity type I interferon receptor binding | Bos taurus | Antiviral defense Cytokine Disulfide bond Glycoprotein Hormone Pregnancy Reference proteome Secreted Signal | MAFVLSLLMA | MAFVLSLLMALVLVSYGPGRSLGCYLSEDHMLGARENLRLLARMNRLSPHPCLQDRKDFGLPQEMVEGNQLQKDQAISVLHEMLQQCFNLFYTEHSSAAWNTTLLEQLCTGLQQQLEDLDACLGPVMGEKDSDMGRMGPILTVKKYFQGIHVYLKEKEYSDCAWEIIRVEMMRALSSSTTLQKRLRKMGGDLNSL | adaptive immune response B cell differentiation B cell proliferation cytokine-mediated signaling pathway defense response to virus female pregnancy humoral immune response natural killer cell activation involved in immune response positive regulation of cellular biosynthetic process positive regulation of peptidyl-serine phosphorylation of STAT protein response to exogenous dsRNA T cell activation involved in immune response extracellular space cytokine activity hormone activity type I interferon receptor binding Bos taurus Antiviral defense Cytokine Disulfide bond Glycoprotein Hormone Pregnancy Reference proteome Secreted Signal MAFVLSLLMA MAFVLSLLMALVLVSYGPGRSLGCYLSEDHMLGARENLRLLARMNRLSPHPCLQDRKDFGLPQEMVEGNQLQKDQAISVLHEMLQQCFNLFYTEHSSAAWNTTLLEQLCTGLQQQLEDLDACLGPVMGEKDSDMGRMGPILTVKKYFQGIHVYLKEKEYSDCAWEIIRVEMMRALSSSTTLQKRLRKMGGDLNSL |
de novo' pyrimidine nucleobase biosynthetic process CDP biosynthetic process nucleobase-containing compound metabolic process phosphorylation UDP biosynthetic process | cytoplasm; nucleus | adenylate kinase activity ATP binding cytidylate kinase activity UMP kinase activity UMP/dUMP kinase activity | Saccharomyces cerevisiae | 3D-structure ATP-binding Cytoplasm Kinase Nucleotide-binding Nucleus Pyrimidine biosynthesis Reference proteome Transferase | MTAATTSQPA | MTAATTSQPAFSPDQVSVIFVLGGPGAGKGTQCEKLVKDYSFVHLSAGDLLRAEQGRAGSQYGELIKNCIKEGQIVPQEITLALLRNAISDNVKANKHKFLIDGFPRKMDQAISFERDIVESKFILFFDCPEDIMLERLLERGKTSGRSDDNIESIKKRFNTFKETSMPVIEYFETKSKVVRVRCDRSVEDVYKDVQDAIRDSL | de novo' pyrimidine nucleobase biosynthetic process CDP biosynthetic process nucleobase-containing compound metabolic process phosphorylation UDP biosynthetic process cytoplasm; nucleus adenylate kinase activity ATP binding cytidylate kinase activity UMP kinase activity UMP/dUMP kinase activity Saccharomyces cerevisiae 3D-structure ATP-binding Cytoplasm Kinase Nucleotide-binding Nucleus Pyrimidine biosynthesis Reference proteome Transferase MTAATTSQPA MTAATTSQPAFSPDQVSVIFVLGGPGAGKGTQCEKLVKDYSFVHLSAGDLLRAEQGRAGSQYGELIKNCIKEGQIVPQEITLALLRNAISDNVKANKHKFLIDGFPRKMDQAISFERDIVESKFILFFDCPEDIMLERLLERGKTSGRSDDNIESIKKRFNTFKETSMPVIEYFETKSKVVRVRCDRSVEDVYKDVQDAIRDSL |
apoptotic signaling pathway cell surface receptor signaling pathway defense response to bacterium leukocyte tethering or rolling negative regulation of cell adhesion negative regulation of T cell activation negative regulation of T cell proliferation negative regulation of type IV hypersensitivity negative thymic T cell selection positive regulation of protein phosphorylation positive regulation of T cell migration positive regulation of T cell proliferation positive regulation of tumor necrosis factor production regulation of defense response to virus regulation of immune response regulation of T cell migration response to protozoan T cell costimulation T cell proliferation T-helper 1 cell lineage commitment | basement membrane; cell surface; cleavage furrow; external side of plasma membrane; extracellular space; microvillus; plasma membrane; PML body; uropod | heat shock protein binding Hsp70 protein binding protein domain specific binding transmembrane signaling receptor activity | Mus musculus | 3D-structure Cell projection Direct protein sequencing Glycoprotein Membrane Nucleus Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix Ubl conjugation | MALHLLLLFG | MALHLLLLFGACWVQVASPDSLQRTTMLPSTPHITAPSTSEAQNASPSVSVGSGTVDSKETISPWGQTTIPVSLTPLETTELSSLETSAGASMSTPVPEPTASQEVSSKTSALLPEPSNVASDPPVTAANPVTDGPAANPVTDGTAASTSISKGTSAPPTTVTTSSNETSGPSVATTVSSKTSGPPVTTATGSLGPSSEMHGLPATTATSSVESSSVARGTSVSSRKTSTTSTQDPITTRSPSQESSGMLLVPMLIALVVVLALVALLLLWRQRQKRRTGALTLSGGGKRNGVVDAWAGPARVPDEEATTTSGAGGNKGSEVLETEGSGQRPTLTTFFSRRKSRQGSLVLEELKPGSGPNLKGEEEPLVGSEDEAVETPTSDGPQAKDEAAPQSL | apoptotic signaling pathway cell surface receptor signaling pathway defense response to bacterium leukocyte tethering or rolling negative regulation of cell adhesion negative regulation of T cell activation negative regulation of T cell proliferation negative regulation of type IV hypersensitivity negative thymic T cell selection positive regulation of protein phosphorylation positive regulation of T cell migration positive regulation of T cell proliferation positive regulation of tumor necrosis factor production regulation of defense response to virus regulation of immune response regulation of T cell migration response to protozoan T cell costimulation T cell proliferation T-helper 1 cell lineage commitment basement membrane; cell surface; cleavage furrow; external side of plasma membrane; extracellular space; microvillus; plasma membrane; PML body; uropod heat shock protein binding Hsp70 protein binding protein domain specific binding transmembrane signaling receptor activity Mus musculus 3D-structure Cell projection Direct protein sequencing Glycoprotein Membrane Nucleus Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix Ubl conjugation MALHLLLLFG MALHLLLLFGACWVQVASPDSLQRTTMLPSTPHITAPSTSEAQNASPSVSVGSGTVDSKETISPWGQTTIPVSLTPLETTELSSLETSAGASMSTPVPEPTASQEVSSKTSALLPEPSNVASDPPVTAANPVTDGPAANPVTDGTAASTSISKGTSAPPTTVTTSSNETSGPSVATTVSSKTSGPPVTTATGSLGPSSEMHGLPATTATSSVESSSVARGTSVSSRKTSTTSTQDPITTRSPSQESSGMLLVPMLIALVVVLALVALLLLWRQRQKRRTGALTLSGGGKRNGVVDAWAGPARVPDEEATTTSGAGGNKGSEVLETEGSGQRPTLTTFFSRRKSRQGSLVLEELKPGSGPNLKGEEEPLVGSEDEAVETPTSDGPQAKDEAAPQSL |
carbohydrate metabolic process cell wall organization fungal-type cell wall organization | cell surface; extracellular region; fungal-type cell wall; fungal-type vacuole | chitin binding glucan endo-1,3-beta-D-glucosidase activity glucan exo-1,3-beta-glucosidase activity | Saccharomyces cerevisiae | Cell wall Cell wall biogenesis/degradation Chitin-binding Direct protein sequencing Glycoprotein Glycosidase Hydrolase Reference proteome Secreted Signal | MRFSTTLATA | MRFSTTLATAATALFFTASQVSAIGELAFNLGVKNNDGTCKSTSDYETELQALKSYTSTVKVYAASDCNTLQNLGPAAEAEGFTIFVGVWPTDDSHYAAEKAALQTYLPKIKESTVAGFLVGSEALYRNDLTASQLSDKINDVRSVVADISDSDGKSYSGKQVGTVDSWNVLVAGYNSAVIEASDFVMANAFSYWQGQTMQNASYSFFDDIMQALQVIQSTKGSTDITFWVGETGWPTDGTNFESSYPSVDNAKQFWKEGICSMRAWGVNVIVFEAFDEDWKPNTSGTSDVEKHWGVFTSSDNLKYSLDCDFS | carbohydrate metabolic process cell wall organization fungal-type cell wall organization cell surface; extracellular region; fungal-type cell wall; fungal-type vacuole chitin binding glucan endo-1,3-beta-D-glucosidase activity glucan exo-1,3-beta-glucosidase activity Saccharomyces cerevisiae Cell wall Cell wall biogenesis/degradation Chitin-binding Direct protein sequencing Glycoprotein Glycosidase Hydrolase Reference proteome Secreted Signal MRFSTTLATA MRFSTTLATAATALFFTASQVSAIGELAFNLGVKNNDGTCKSTSDYETELQALKSYTSTVKVYAASDCNTLQNLGPAAEAEGFTIFVGVWPTDDSHYAAEKAALQTYLPKIKESTVAGFLVGSEALYRNDLTASQLSDKINDVRSVVADISDSDGKSYSGKQVGTVDSWNVLVAGYNSAVIEASDFVMANAFSYWQGQTMQNASYSFFDDIMQALQVIQSTKGSTDITFWVGETGWPTDGTNFESSYPSVDNAKQFWKEGICSMRAWGVNVIVFEAFDEDWKPNTSGTSDVEKHWGVFTSSDNLKYSLDCDFS |
protein folding protein localization protein targeting to mitochondrion | cytoplasm | ATPase inhibitor activity Hsp70 protein binding Hsp90 protein binding mRNA binding | Saccharomyces cerevisiae | 3D-structure Cytoplasm Direct protein sequencing Glycoprotein Isopeptide bond Phosphoprotein Reference proteome Repeat Stress response TPR repeat Ubl conjugation | MSLTADEYKQ | MSLTADEYKQQGNAAFTAKDYDKAIELFTKAIEVSETPNHVLYSNRSACYTSLKKFSDALNDANECVKINPSWSKGYNRLGAAHLGLGDLDEAESNYKKALELDASNKAAKEGLDQVHRTQQARQAQPDLGLTQLFADPNLIENLKKNPKTSEMMKDPQLVAKLIGYKQNPQAIGQDLFTDPRLMTIMATLMGVDLNMDDINQSNSMPKEPETSKSTEQKKDAEPQSDSTTSKENSSKAPQKEESKESEPMEVDEDDSKIEADKEKAEGNKFYKARQFDEAIEHYNKAWELHKDITYLNNRAAAEYEKGEYETAISTLNDAVEQGREMRADYKVISKSFARIGNAYHKLGDLKKTIEYYQKSLTEHRTADILTKLRNAEKELKKAEAEAYVNPEKAEEARLEGKEYFTKSDWPNAVKAYTEMIKRAPEDARGYSNRAAALAKLMSFPEAIADCNKAIEKDPNFVRAYIRKATAQIAVKEYASALETLDAARTKDAEVNNGSSAREIDQLYYKASQQRFQPGTSNETPEETYQRAMKDPEVAAIMQDPVMQSILQQAQQNPAALQEHMKNPEVFKKIQTLIAAGIIRTGR | protein folding protein localization protein targeting to mitochondrion cytoplasm ATPase inhibitor activity Hsp70 protein binding Hsp90 protein binding mRNA binding Saccharomyces cerevisiae 3D-structure Cytoplasm Direct protein sequencing Glycoprotein Isopeptide bond Phosphoprotein Reference proteome Repeat Stress response TPR repeat Ubl conjugation MSLTADEYKQ MSLTADEYKQQGNAAFTAKDYDKAIELFTKAIEVSETPNHVLYSNRSACYTSLKKFSDALNDANECVKINPSWSKGYNRLGAAHLGLGDLDEAESNYKKALELDASNKAAKEGLDQVHRTQQARQAQPDLGLTQLFADPNLIENLKKNPKTSEMMKDPQLVAKLIGYKQNPQAIGQDLFTDPRLMTIMATLMGVDLNMDDINQSNSMPKEPETSKSTEQKKDAEPQSDSTTSKENSSKAPQKEESKESEPMEVDEDDSKIEADKEKAEGNKFYKARQFDEAIEHYNKAWELHKDITYLNNRAAAEYEKGEYETAISTLNDAVEQGREMRADYKVISKSFARIGNAYHKLGDLKKTIEYYQKSLTEHRTADILTKLRNAEKELKKAEAEAYVNPEKAEEARLEGKEYFTKSDWPNAVKAYTEMIKRAPEDARGYSNRAAALAKLMSFPEAIADCNKAIEKDPNFVRAYIRKATAQIAVKEYASALETLDAARTKDAEVNNGSSAREIDQLYYKASQQRFQPGTSNETPEETYQRAMKDPEVAAIMQDPVMQSILQQAQQNPAALQEHMKNPEVFKKIQTLIAAGIIRTGR |
3'-phosphoadenosine 5'-phosphosulfate metabolic process cellular response to vitamin D cholesterol metabolic process ethanol catabolic process response to activity response to insecticide response to nutrient levels steroid metabolic process sulfation thyroid hormone metabolic process xenobiotic metabolic process | cytoplasm | 3'-phosphoadenosine 5'-phosphosulfate binding alcohol sulfotransferase activity bile-salt sulfotransferase activity steroid sulfotransferase activity sulfotransferase activity transferase activity | Rattus norvegicus | Cytoplasm Lipid metabolism Reference proteome Steroid metabolism Transferase | MPDYTWFEGI | MPDYTWFEGIPFHAFGISKETLQNVCNKFVVKDEDLILLAYPKSGTNWLIEIVCLIQTKGDPKWIQSVTIWDRSPWIETDLGYDMLIKKKGPRLITSHLPMHLFSKSLFSSKAKVIYLVRNPRDVLVSGYYFWGNSTLAKKPDSLGTYVEWFLKGNVLYGSWFEHIRAWLSMREWDNFLLLYYEDMKKDTMGTIKKICDFLGKKLEPDELDLVLKYSSFQVMKENDMSNYSLLMKKSIFTGIGLMRKGTVGDWKNHFTVSQAEAFDKVFQEKMAGFPPGMFPWE | 3'-phosphoadenosine 5'-phosphosulfate metabolic process cellular response to vitamin D cholesterol metabolic process ethanol catabolic process response to activity response to insecticide response to nutrient levels steroid metabolic process sulfation thyroid hormone metabolic process xenobiotic metabolic process cytoplasm 3'-phosphoadenosine 5'-phosphosulfate binding alcohol sulfotransferase activity bile-salt sulfotransferase activity steroid sulfotransferase activity sulfotransferase activity transferase activity Rattus norvegicus Cytoplasm Lipid metabolism Reference proteome Steroid metabolism Transferase MPDYTWFEGI MPDYTWFEGIPFHAFGISKETLQNVCNKFVVKDEDLILLAYPKSGTNWLIEIVCLIQTKGDPKWIQSVTIWDRSPWIETDLGYDMLIKKKGPRLITSHLPMHLFSKSLFSSKAKVIYLVRNPRDVLVSGYYFWGNSTLAKKPDSLGTYVEWFLKGNVLYGSWFEHIRAWLSMREWDNFLLLYYEDMKKDTMGTIKKICDFLGKKLEPDELDLVLKYSSFQVMKENDMSNYSLLMKKSIFTGIGLMRKGTVGDWKNHFTVSQAEAFDKVFQEKMAGFPPGMFPWE |
malate metabolic process NADH metabolic process oxaloacetate metabolic process tricarboxylic acid cycle | chloroplast | L-malate dehydrogenase activity malate dehydrogenase (NADP+) activity | Zea mays | Chloroplast Direct protein sequencing Disulfide bond NADP Oxidoreductase Plastid Reference proteome Transit peptide | MGLSTVYSPA | MGLSTVYSPAGPRLVPAPLGRCRSAQPRRPRRAPLATVRCSVDATKQAQDGVATAVATEAPASRKECFGVFCTTYDLKAEDKTKSWRKLVNVAVSGAAGMISNHLLFKLASGEVFGQDQPIALKLLGSERSFQALEGVAMELEDSLYPLLREVSIGIDPYVVFQDVDWALLIGAKPRGPGMERAALLDINGQIFADQGKALNAVASRNDEVLVVGNPCNTNALICLKNAPNIPAKNFHALTRLDENRAKCQLALKAGVFYDKVSNVTIWGNHSTTQVPDFLNAKIDGRPVKEVIKDTKWLEEEFTLTVQKRGGVLIQKWGRSSAASTAVSIVDAIRSLVTPTPEGDWFSTGVYTTGNPYGIAEDIVFSMPCRSKGDGDYELASDVLMDDFLWERIKKSEAELLAEKKCVAHLTGEGNAFCDLPEDTMLPGEV | malate metabolic process NADH metabolic process oxaloacetate metabolic process tricarboxylic acid cycle chloroplast L-malate dehydrogenase activity malate dehydrogenase (NADP+) activity Zea mays Chloroplast Direct protein sequencing Disulfide bond NADP Oxidoreductase Plastid Reference proteome Transit peptide MGLSTVYSPA MGLSTVYSPAGPRLVPAPLGRCRSAQPRRPRRAPLATVRCSVDATKQAQDGVATAVATEAPASRKECFGVFCTTYDLKAEDKTKSWRKLVNVAVSGAAGMISNHLLFKLASGEVFGQDQPIALKLLGSERSFQALEGVAMELEDSLYPLLREVSIGIDPYVVFQDVDWALLIGAKPRGPGMERAALLDINGQIFADQGKALNAVASRNDEVLVVGNPCNTNALICLKNAPNIPAKNFHALTRLDENRAKCQLALKAGVFYDKVSNVTIWGNHSTTQVPDFLNAKIDGRPVKEVIKDTKWLEEEFTLTVQKRGGVLIQKWGRSSAASTAVSIVDAIRSLVTPTPEGDWFSTGVYTTGNPYGIAEDIVFSMPCRSKGDGDYELASDVLMDDFLWERIKKSEAELLAEKKCVAHLTGEGNAFCDLPEDTMLPGEV |
cellular defense response inflammatory response negative regulation of activation-induced cell death of T cells negative regulation of cytokine production negative regulation of DNA-templated transcription negative regulation of extrinsic apoptotic signaling pathway positive regulation of B cell proliferation positive regulation of immunoglobulin production regulation of apoptotic process T cell proliferation | cell surface; external side of plasma membrane; plasma membrane | tumor necrosis factor receptor activity | Rattus norvegicus | Disulfide bond Glycoprotein Membrane Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix | MYVWVQQPTA | MYVWVQQPTAFLLLGLSLGVTVKLNCVKDTYPSGHKCCRECQPGHGMVSRCDHTRDTVCHPCEPGFYNEAVNYDTCKQCTQCNHRSGSELKQNCTPTEDTVCQCRPGTQPRQDSSHKLGVDCVPCPPGHFSPGSNQACKPWTNCTLSGKQIRHPASNSLDTVCEDRSLLATLLWETQRTTFRPTTVPSTTVWPRTSQLPSTPTLVAPEGPAFAVILGLGLGLLAPLTVLLALYLLRKAWRSPNTPKPCWGNSFRTPIQEEQTDTHFTLAKI | cellular defense response inflammatory response negative regulation of activation-induced cell death of T cells negative regulation of cytokine production negative regulation of DNA-templated transcription negative regulation of extrinsic apoptotic signaling pathway positive regulation of B cell proliferation positive regulation of immunoglobulin production regulation of apoptotic process T cell proliferation cell surface; external side of plasma membrane; plasma membrane tumor necrosis factor receptor activity Rattus norvegicus Disulfide bond Glycoprotein Membrane Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix MYVWVQQPTA MYVWVQQPTAFLLLGLSLGVTVKLNCVKDTYPSGHKCCRECQPGHGMVSRCDHTRDTVCHPCEPGFYNEAVNYDTCKQCTQCNHRSGSELKQNCTPTEDTVCQCRPGTQPRQDSSHKLGVDCVPCPPGHFSPGSNQACKPWTNCTLSGKQIRHPASNSLDTVCEDRSLLATLLWETQRTTFRPTTVPSTTVWPRTSQLPSTPTLVAPEGPAFAVILGLGLGLLAPLTVLLALYLLRKAWRSPNTPKPCWGNSFRTPIQEEQTDTHFTLAKI |
cytoplasm protein quality control by the ubiquitin-proteasome system mitochondria-associated ubiquitin-dependent protein catabolic process protein monoubiquitination protein polyubiquitination protein ubiquitination rescue of stalled ribosome ribosome-associated ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway | cytoplasm; nucleus; ubiquitin ligase complex | ATP binding proteasome binding protein-macromolecule adaptor activity ubiquitin binding ubiquitin conjugating enzyme activity ubiquitin protein ligase binding ubiquitin-protein transferase activity | Saccharomyces cerevisiae | 3D-structure ATP-binding Direct protein sequencing Isopeptide bond Nucleotide-binding Phosphoprotein Reference proteome Stress response Transferase Ubl conjugation Ubl conjugation pathway | MSSSKRIAKE | MSSSKRIAKELSDLERDPPTSCSAGPVGDDLYHWQASIMGPADSPYAGGVFFLSIHFPTDYPFKPPKISFTTKIYHPNINANGNICLDILKDQWSPALTLSKVLLSICSLLTDANPDDPLVPEIAHIYKTDRPKYEATAREWTKKYAV | cytoplasm protein quality control by the ubiquitin-proteasome system mitochondria-associated ubiquitin-dependent protein catabolic process protein monoubiquitination protein polyubiquitination protein ubiquitination rescue of stalled ribosome ribosome-associated ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway cytoplasm; nucleus; ubiquitin ligase complex ATP binding proteasome binding protein-macromolecule adaptor activity ubiquitin binding ubiquitin conjugating enzyme activity ubiquitin protein ligase binding ubiquitin-protein transferase activity Saccharomyces cerevisiae 3D-structure ATP-binding Direct protein sequencing Isopeptide bond Nucleotide-binding Phosphoprotein Reference proteome Stress response Transferase Ubl conjugation Ubl conjugation pathway MSSSKRIAKE MSSSKRIAKELSDLERDPPTSCSAGPVGDDLYHWQASIMGPADSPYAGGVFFLSIHFPTDYPFKPPKISFTTKIYHPNINANGNICLDILKDQWSPALTLSKVLLSICSLLTDANPDDPLVPEIAHIYKTDRPKYEATAREWTKKYAV |
protein polyubiquitination ubiquitin-dependent protein catabolic process | nucleus; ubiquitin ligase complex | ATP binding proteasome binding ubiquitin conjugating enzyme activity ubiquitin protein ligase binding ubiquitin-protein transferase activity | Saccharomyces cerevisiae | ATP-binding Direct protein sequencing Isopeptide bond Nucleotide-binding Phosphoprotein Reference proteome Stress response Transferase Ubl conjugation Ubl conjugation pathway | MSSSKRIAKE | MSSSKRIAKELSDLGRDPPASCSAGPVGDDLYHWQASIMGPSDSPYAGGVFFLSIHFPTDYPFKPPKVNFTTKIYHPNINSSGNICLDILKDQWSPALTLSKVLLSICSLLTDANPDDPLVPEIAQIYKTDKAKYEATAKEWTKKYAV | protein polyubiquitination ubiquitin-dependent protein catabolic process nucleus; ubiquitin ligase complex ATP binding proteasome binding ubiquitin conjugating enzyme activity ubiquitin protein ligase binding ubiquitin-protein transferase activity Saccharomyces cerevisiae ATP-binding Direct protein sequencing Isopeptide bond Nucleotide-binding Phosphoprotein Reference proteome Stress response Transferase Ubl conjugation Ubl conjugation pathway MSSSKRIAKE MSSSKRIAKELSDLGRDPPASCSAGPVGDDLYHWQASIMGPSDSPYAGGVFFLSIHFPTDYPFKPPKVNFTTKIYHPNINSSGNICLDILKDQWSPALTLSKVLLSICSLLTDANPDDPLVPEIAQIYKTDKAKYEATAKEWTKKYAV |
generation of precursor metabolites and energy glycogen biosynthetic process glycogen catabolic process glycogen metabolic process positive regulation of glycogen catabolic process protein phosphorylation | cytosol; phosphorylase kinase complex | ATP binding calmodulin binding enzyme binding phosphorylase kinase activity protein serine/threonine kinase activity tau-protein kinase activity | Homo sapiens | 3D-structure Alternative splicing ATP-binding Calmodulin-binding Carbohydrate metabolism Disease variant Glycogen metabolism Glycogen storage disease Kinase Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MTLDVGPEDE | MTLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAERLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFERCEGSQPWNLTPRQRFRVAVWTVLAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDNCAFRLYGHWVKKGEQQNRAALFQHRPPGPFPIMGPEEEGDSAAITEDEAVLVLG | generation of precursor metabolites and energy glycogen biosynthetic process glycogen catabolic process glycogen metabolic process positive regulation of glycogen catabolic process protein phosphorylation cytosol; phosphorylase kinase complex ATP binding calmodulin binding enzyme binding phosphorylase kinase activity protein serine/threonine kinase activity tau-protein kinase activity Homo sapiens 3D-structure Alternative splicing ATP-binding Calmodulin-binding Carbohydrate metabolism Disease variant Glycogen metabolism Glycogen storage disease Kinase Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase MTLDVGPEDE MTLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAERLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFERCEGSQPWNLTPRQRFRVAVWTVLAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDNCAFRLYGHWVKKGEQQNRAALFQHRPPGPFPIMGPEEEGDSAAITEDEAVLVLG |
amino acid biosynthetic process aromatic amino acid family biosynthetic process chorismate biosynthetic process shikimate metabolic process | cytosol | NADP binding nucleotide binding shikimate 3-dehydrogenase (NADP+) activity | Escherichia coli | 3D-structure Amino-acid biosynthesis Aromatic amino acid biosynthesis Direct protein sequencing NADP Oxidoreductase Reference proteome | METYAVFGNP | METYAVFGNPIAHSKSPFIHQQFAQQLNIEHPYGRVLAPINDFINTLNAFFSAGGKGANVTVPFKEEAFARADELTERAALAGAVNTLMRLEDGRLLGDNTDGVGLLSDLERLSFIRPGLRILLIGAGGASRGVLLPLLSLDCAVTITNRTVSRAEELAKLFAHTGSIQALSMDELEGHEFDLIINATSSGISGDIPAIPSSLIHPGIYCYDMFYQKGKTPFLAWCEQRGSKRNADGLGMLVAQAAHAFLLWHGVLPDVEPVIKQLQEELSA | amino acid biosynthetic process aromatic amino acid family biosynthetic process chorismate biosynthetic process shikimate metabolic process cytosol NADP binding nucleotide binding shikimate 3-dehydrogenase (NADP+) activity Escherichia coli 3D-structure Amino-acid biosynthesis Aromatic amino acid biosynthesis Direct protein sequencing NADP Oxidoreductase Reference proteome METYAVFGNP METYAVFGNPIAHSKSPFIHQQFAQQLNIEHPYGRVLAPINDFINTLNAFFSAGGKGANVTVPFKEEAFARADELTERAALAGAVNTLMRLEDGRLLGDNTDGVGLLSDLERLSFIRPGLRILLIGAGGASRGVLLPLLSLDCAVTITNRTVSRAEELAKLFAHTGSIQALSMDELEGHEFDLIINATSSGISGDIPAIPSSLIHPGIYCYDMFYQKGKTPFLAWCEQRGSKRNADGLGMLVAQAAHAFLLWHGVLPDVEPVIKQLQEELSA |
fusion of virus membrane with host plasma membrane negative regulation of immune system process receptor-mediated virion attachment to host cell | host cell plasma membrane; membrane; viral envelope; virion membrane | host cell surface receptor binding identical protein binding protein homodimerization activity sialate 4-O-acetylesterase activity sialate 9-O-acetylesterase activity sialate O-acetylesterase activity signaling receptor binding | Bovine coronavirus | 3D-structure Direct protein sequencing Disulfide bond Glycoprotein Hemagglutinin Host cell membrane Host membrane Hydrolase Membrane Signal Transmembrane Transmembrane helix Viral envelope protein Virion | MFLLLRFVLV | MFLLLRFVLVSCIIGSLGFDNPPTNVVSHLNGDWFLFGDSRSDCNHVVNTNPRNYSYMDLNPALCDSGKISSKAGNSIFRSFHFTDFYNYTGEGQQIIFYEGVNFTPYHAFKCTTSGSNDIWMQNKGLFYTQVYKNMAVYRSLTFVNVPYVYNGSAQSTALCKSGSLVLNNPAYIAREANFGDYYYKVEADFYLSGCDEYIVPLCIFNGKFLSNTKYYDDSQYYFNKDTGVIYGLNSTETITTGFDFNCHYLVLPSGNYLAISNELLLTVPTKAICLNKRKDFTPVQVVDSRWNNARQSDNMTAVACQPPYCYFRNSTTNYVGVYDINHGDAGFTSILSGLLYDSPCFSQQGVFRYDNVSSVWPLYSYGRCPTAADINTPDVPICVYDPLPLILLGILLGVAVIIIVVLLLYFMVDNGTRLHDA | fusion of virus membrane with host plasma membrane negative regulation of immune system process receptor-mediated virion attachment to host cell host cell plasma membrane; membrane; viral envelope; virion membrane host cell surface receptor binding identical protein binding protein homodimerization activity sialate 4-O-acetylesterase activity sialate 9-O-acetylesterase activity sialate O-acetylesterase activity signaling receptor binding Bovine coronavirus 3D-structure Direct protein sequencing Disulfide bond Glycoprotein Hemagglutinin Host cell membrane Host membrane Hydrolase Membrane Signal Transmembrane Transmembrane helix Viral envelope protein Virion MFLLLRFVLV MFLLLRFVLVSCIIGSLGFDNPPTNVVSHLNGDWFLFGDSRSDCNHVVNTNPRNYSYMDLNPALCDSGKISSKAGNSIFRSFHFTDFYNYTGEGQQIIFYEGVNFTPYHAFKCTTSGSNDIWMQNKGLFYTQVYKNMAVYRSLTFVNVPYVYNGSAQSTALCKSGSLVLNNPAYIAREANFGDYYYKVEADFYLSGCDEYIVPLCIFNGKFLSNTKYYDDSQYYFNKDTGVIYGLNSTETITTGFDFNCHYLVLPSGNYLAISNELLLTVPTKAICLNKRKDFTPVQVVDSRWNNARQSDNMTAVACQPPYCYFRNSTTNYVGVYDINHGDAGFTSILSGLLYDSPCFSQQGVFRYDNVSSVWPLYSYGRCPTAADINTPDVPICVYDPLPLILLGILLGVAVIIIVVLLLYFMVDNGTRLHDA |
DNA damage response donor selection maturation of SSU-rRNA nucleolar large rRNA transcription by RNA polymerase I phosphorylation regulation of cell cycle regulation of ribosomal protein gene transcription by RNA polymerase II regulation of transcription by RNA polymerase I regulation of transcription by RNA polymerase III ribosomal small subunit assembly | CURI complex; cytosol; nucleolus; nucleoplasm; nucleus; protein kinase CK2 complex; small-subunit processome; UTP-C complex | ATP binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity | Saccharomyces cerevisiae | 3D-structure ATP-binding Direct protein sequencing Kinase Nucleotide-binding Reference proteome Serine/threonine-protein kinase Transferase | MKCRVWSEAR | MKCRVWSEARVYTNINKQRTEEYWDYENTVIDWSTNTKDYEIENKVGRGKYSEVFQGVKLDSKVKIVIKMLKPVKKKKIKREIKILTDLSNEKVPPTTLPFQKDQYYTNQKEDVLKFIRPYIFDQPHNGHANIIHLFDIIKDPISKTPALVFEYVDNVDFRILYPKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLGTSDFEKYLLKYEITLPREFYDMDQYIRKPWHRFINDGNKHLSGNDEIIDLIDNLLRYDHQERLTAKEAMGHPWFAPIREQIEK | DNA damage response donor selection maturation of SSU-rRNA nucleolar large rRNA transcription by RNA polymerase I phosphorylation regulation of cell cycle regulation of ribosomal protein gene transcription by RNA polymerase II regulation of transcription by RNA polymerase I regulation of transcription by RNA polymerase III ribosomal small subunit assembly CURI complex; cytosol; nucleolus; nucleoplasm; nucleus; protein kinase CK2 complex; small-subunit processome; UTP-C complex ATP binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity Saccharomyces cerevisiae 3D-structure ATP-binding Direct protein sequencing Kinase Nucleotide-binding Reference proteome Serine/threonine-protein kinase Transferase MKCRVWSEAR MKCRVWSEARVYTNINKQRTEEYWDYENTVIDWSTNTKDYEIENKVGRGKYSEVFQGVKLDSKVKIVIKMLKPVKKKKIKREIKILTDLSNEKVPPTTLPFQKDQYYTNQKEDVLKFIRPYIFDQPHNGHANIIHLFDIIKDPISKTPALVFEYVDNVDFRILYPKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLGTSDFEKYLLKYEITLPREFYDMDQYIRKPWHRFINDGNKHLSGNDEIIDLIDNLLRYDHQERLTAKEAMGHPWFAPIREQIEK |
carbohydrate metabolic process defense response | vacuole | glucan endo-1,3-beta-D-glucosidase activity | Nicotiana tabacum | Direct protein sequencing Glycoprotein Glycosidase Hydrolase Plant defense Pyrrolidone carboxylic acid Reference proteome Signal Vacuole | MSTSSHKHNT | MSTSSHKHNTPQMAAITLLGLLLVASSIDIAGAQSIGVCYGMLGNNLPNHWEVIQLYKSRNIGRLRLYDPNHGALQALKGSNIEVMLGLPNSDVKHIASGMEHARWWVQKNVKDFWPDVKIKYIAVGNEISPVTGTSYLTSFLTPAMVNIYKAIGEAGLGNNIKVSTSVDMTLIGNSYPPSQGSFRNDARWFTDPIVGFLRDTRAPLLVNIYPYFSYSGNPGQISLPYSLFTAPNVVVQDGSRQYRNLFDAMLDSVYAALERSGGASVGIVVSESGWPSAGAFGATYDNAATYLRNLIQHAKEGSPRKPGPIETYIFAMFDENNKNPELEKHFGLFSPNKQPKYNINFGVSGGVWDSSVETNATASLVSEM | carbohydrate metabolic process defense response vacuole glucan endo-1,3-beta-D-glucosidase activity Nicotiana tabacum Direct protein sequencing Glycoprotein Glycosidase Hydrolase Plant defense Pyrrolidone carboxylic acid Reference proteome Signal Vacuole MSTSSHKHNT MSTSSHKHNTPQMAAITLLGLLLVASSIDIAGAQSIGVCYGMLGNNLPNHWEVIQLYKSRNIGRLRLYDPNHGALQALKGSNIEVMLGLPNSDVKHIASGMEHARWWVQKNVKDFWPDVKIKYIAVGNEISPVTGTSYLTSFLTPAMVNIYKAIGEAGLGNNIKVSTSVDMTLIGNSYPPSQGSFRNDARWFTDPIVGFLRDTRAPLLVNIYPYFSYSGNPGQISLPYSLFTAPNVVVQDGSRQYRNLFDAMLDSVYAALERSGGASVGIVVSESGWPSAGAFGATYDNAATYLRNLIQHAKEGSPRKPGPIETYIFAMFDENNKNPELEKHFGLFSPNKQPKYNINFGVSGGVWDSSVETNATASLVSEM |
penicillin biosynthetic process | peroxisomal matrix | acyl coenzyme A: isopenicillin N acyltransferase activity isopenicillin-N N-acyltransferase activity | Penicillium chrysogenum | 3D-structure Acyltransferase Antibiotic biosynthesis Direct protein sequencing Peroxisome Transferase Zymogen | MLHILCQGTP | MLHILCQGTPFEIGYEHGSAAKAVIARSIDFAVDLIRGKTKKTDEELKQVLSQLGRVIEERWPKYYEEIRGIAKGAERDVSEIVMLNTRTEFAYGLKAARDGCTTAYCQLPNGALQGQNWDFFSATKENLIRLTIRQAGLPTIKFITEAGIIGKVGFNSAGVAVNYNALHLQGLRPTGVPSHIALRIALESTSPSQAYDRIVEQGGMAASAFIMVGNGHEAFGLEFSPTSIRKQVLDANGRMVHTNHCLLQHGKNEKELDPLPDSWNRHQRMEFLLDGFDGTKQAFAQLWADEDNYPFSICRAYEEGKSRGATLFNIIYDHARREATVRLGRPTNPDEMFVMRFDEEDERSALNARL | penicillin biosynthetic process peroxisomal matrix acyl coenzyme A: isopenicillin N acyltransferase activity isopenicillin-N N-acyltransferase activity Penicillium chrysogenum 3D-structure Acyltransferase Antibiotic biosynthesis Direct protein sequencing Peroxisome Transferase Zymogen MLHILCQGTP MLHILCQGTPFEIGYEHGSAAKAVIARSIDFAVDLIRGKTKKTDEELKQVLSQLGRVIEERWPKYYEEIRGIAKGAERDVSEIVMLNTRTEFAYGLKAARDGCTTAYCQLPNGALQGQNWDFFSATKENLIRLTIRQAGLPTIKFITEAGIIGKVGFNSAGVAVNYNALHLQGLRPTGVPSHIALRIALESTSPSQAYDRIVEQGGMAASAFIMVGNGHEAFGLEFSPTSIRKQVLDANGRMVHTNHCLLQHGKNEKELDPLPDSWNRHQRMEFLLDGFDGTKQAFAQLWADEDNYPFSICRAYEEGKSRGATLFNIIYDHARREATVRLGRPTNPDEMFVMRFDEEDERSALNARL |
B cell lineage commitment cell development chromatin remodeling erythrocyte differentiation gastrulation gene expression immunoglobulin V(D)J recombination lymphocyte differentiation natural killer cell differentiation negative regulation of transcription by RNA polymerase II nervous system development Peyer's patch development positive regulation of B cell proliferation positive regulation of cell cycle positive regulation of DNA-binding transcription factor activity positive regulation of DNA-templated transcription positive regulation of gene expression positive regulation of neuron differentiation positive regulation of transcription by RNA polymerase II protein stabilization regulation of DNA-templated transcription regulation of G1/S transition of mitotic cell cycle regulation of transcription by RNA polymerase II response to lipopolysaccharide response to xenobiotic stimulus T cell differentiation in thymus transcription by RNA polymerase II | chromatin; cytoplasm; cytosol; euchromatin; nucleoplasm; nucleosome; nucleus; protein-containing complex; RNA polymerase II transcription regulator complex; transcription regulator complex | bHLH transcription factor binding chromatin binding cis-regulatory region sequence-specific DNA binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor binding DNA-binding transcription repressor activity, RNA polymerase II-specific E-box binding identical protein binding mitogen-activated protein kinase kinase kinase binding PDZ domain binding protein heterodimerization activity protein homodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II-specific DNA-binding transcription factor binding sequence-specific DNA binding vitamin D response element binding | Mus musculus | 3D-structure Alternative splicing Differentiation DNA-binding Isopeptide bond Methylation Neurogenesis Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Ubl conjugation | MMNQSQRMAP | MMNQSQRMAPVGSDKELSDLLDFSMMFPLPVANGKSRPASLGGTQFAGSGLEDRPSSGSWGSSDQNSSSFDPSRTYSEGAHFSDSHSSLPPSTFLGAGLGGKGSERNAYATFGRDTSVGTLSQAGFLPGELSLSSPGPLSPSGIKSSSQYYPSFPSNPRRRAADGGLDTQPKKVRKVPPGLPSSVYPPSSGDSYSRDAAAYPSAKTPSSAYPSPFYVADGSLHPSAELWSTPSQVGFGPMLGDGSSPLPLAPGSSSVGSGTFGGLQQQDRMGYQLHGSEVNGSLPAVSSFSAAPGTYSGTSGHTPPVSGAAAESLLGTRGTTASSSGDALGKALASIYSPDHSSNNFSPSPSTPVGSPQGLPGTSQWPRAGAPSALSPNYDAGLHGLSKMEDRLDEAIHVLRSHAVGTASDLHGLLPGHGALTTSFTGPMSLGGRHAGLVGGSHPEEGLTSGASLLHNHASLPSQPSSLPDLSQRPPDSYSGLGRAGTTAGASEIKREEKEDEEIASVADAEEDKKDLKVPRTRTSPDEDEDDLLPPEQKAEREKERRVANNARERLRVRDINEAFKELGRMCQLHLSSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSGVVGDPQLALSAAHPGLGEAHNPAGHL | B cell lineage commitment cell development chromatin remodeling erythrocyte differentiation gastrulation gene expression immunoglobulin V(D)J recombination lymphocyte differentiation natural killer cell differentiation negative regulation of transcription by RNA polymerase II nervous system development Peyer's patch development positive regulation of B cell proliferation positive regulation of cell cycle positive regulation of DNA-binding transcription factor activity positive regulation of DNA-templated transcription positive regulation of gene expression positive regulation of neuron differentiation positive regulation of transcription by RNA polymerase II protein stabilization regulation of DNA-templated transcription regulation of G1/S transition of mitotic cell cycle regulation of transcription by RNA polymerase II response to lipopolysaccharide response to xenobiotic stimulus T cell differentiation in thymus transcription by RNA polymerase II chromatin; cytoplasm; cytosol; euchromatin; nucleoplasm; nucleosome; nucleus; protein-containing complex; RNA polymerase II transcription regulator complex; transcription regulator complex bHLH transcription factor binding chromatin binding cis-regulatory region sequence-specific DNA binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor binding DNA-binding transcription repressor activity, RNA polymerase II-specific E-box binding identical protein binding mitogen-activated protein kinase kinase kinase binding PDZ domain binding protein heterodimerization activity protein homodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II-specific DNA-binding transcription factor binding sequence-specific DNA binding vitamin D response element binding Mus musculus 3D-structure Alternative splicing Differentiation DNA-binding Isopeptide bond Methylation Neurogenesis Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Ubl conjugation MMNQSQRMAP MMNQSQRMAPVGSDKELSDLLDFSMMFPLPVANGKSRPASLGGTQFAGSGLEDRPSSGSWGSSDQNSSSFDPSRTYSEGAHFSDSHSSLPPSTFLGAGLGGKGSERNAYATFGRDTSVGTLSQAGFLPGELSLSSPGPLSPSGIKSSSQYYPSFPSNPRRRAADGGLDTQPKKVRKVPPGLPSSVYPPSSGDSYSRDAAAYPSAKTPSSAYPSPFYVADGSLHPSAELWSTPSQVGFGPMLGDGSSPLPLAPGSSSVGSGTFGGLQQQDRMGYQLHGSEVNGSLPAVSSFSAAPGTYSGTSGHTPPVSGAAAESLLGTRGTTASSSGDALGKALASIYSPDHSSNNFSPSPSTPVGSPQGLPGTSQWPRAGAPSALSPNYDAGLHGLSKMEDRLDEAIHVLRSHAVGTASDLHGLLPGHGALTTSFTGPMSLGGRHAGLVGGSHPEEGLTSGASLLHNHASLPSQPSSLPDLSQRPPDSYSGLGRAGTTAGASEIKREEKEDEEIASVADAEEDKKDLKVPRTRTSPDEDEDDLLPPEQKAEREKERRVANNARERLRVRDINEAFKELGRMCQLHLSSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSGVVGDPQLALSAAHPGLGEAHNPAGHL |
adaptive immune response antigen processing and presentation, endogenous lipid antigen via MHC class Ib antigen processing and presentation, exogenous lipid antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity | early endosome; external side of plasma membrane; extracellular space; Golgi apparatus; Golgi membrane; late endosome; lysosomal lumen; nucleolus; plasma membrane | endogenous lipid antigen binding exogenous lipid antigen binding lipopeptide binding | Homo sapiens | 3D-structure Adaptive immunity Alternative splicing Disulfide bond Endosome Glycoprotein Golgi apparatus Immunity Immunoglobulin domain Lipid-binding Lysosome Membrane Reference proteome Signal Transmembrane Transmembrane helix Ubl conjugation | MLLLFLLFEG | MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLGDLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYPFEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNILSPHTPSPVFLMGANTQDTKNSRHQFCLAQVSWIKNRVLKKWKTRLNQLW | adaptive immune response antigen processing and presentation, endogenous lipid antigen via MHC class Ib antigen processing and presentation, exogenous lipid antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity early endosome; external side of plasma membrane; extracellular space; Golgi apparatus; Golgi membrane; late endosome; lysosomal lumen; nucleolus; plasma membrane endogenous lipid antigen binding exogenous lipid antigen binding lipopeptide binding Homo sapiens 3D-structure Adaptive immunity Alternative splicing Disulfide bond Endosome Glycoprotein Golgi apparatus Immunity Immunoglobulin domain Lipid-binding Lysosome Membrane Reference proteome Signal Transmembrane Transmembrane helix Ubl conjugation MLLLFLLFEG MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLGDLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYPFEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNILSPHTPSPVFLMGANTQDTKNSRHQFCLAQVSWIKNRVLKKWKTRLNQLW |
antigen processing and presentation, endogenous lipid antigen via MHC class Ib antigen processing and presentation, exogenous lipid antigen via MHC class Ib detection of bacterium heterotypic cell-cell adhesion immune response innate immune response positive regulation of innate immune response positive regulation of T cell mediated cytotoxicity positive regulation of T cell proliferation T cell selection | basolateral plasma membrane; cell surface; cytoplasm; endoplasmic reticulum; endoplasmic reticulum membrane; endosome membrane; external side of plasma membrane; extracellular space; lysosomal membrane; lysosome; plasma membrane | beta-2-microglobulin binding cell adhesion molecule binding endogenous lipid antigen binding exogenous lipid antigen binding histone binding lipid antigen binding lipopeptide binding | Homo sapiens | 3D-structure Cell membrane Disulfide bond Endoplasmic reticulum Endosome Glycoprotein Immunity Immunoglobulin domain Innate immunity Lysosome Membrane Reference proteome Signal Transmembrane Transmembrane helix | MGCLLFLLLW | MGCLLFLLLWALLQAWGSAEVPQRLFPLRCLQISSFANSSWTRTDGLAWLGELQTHSWSNDSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRLSYPLELQVSAGCEVHPGNASNNFFHVAFQGKDILSFQGTSWEPTQEAPLWVNLAIQVLNQDKWTRETVQWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFYPKPVWVKWMRGEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQDIVLYWGGSYTSMGLIALAVLACLLFLLIVGFTSRFKRQTSYQGVL | antigen processing and presentation, endogenous lipid antigen via MHC class Ib antigen processing and presentation, exogenous lipid antigen via MHC class Ib detection of bacterium heterotypic cell-cell adhesion immune response innate immune response positive regulation of innate immune response positive regulation of T cell mediated cytotoxicity positive regulation of T cell proliferation T cell selection basolateral plasma membrane; cell surface; cytoplasm; endoplasmic reticulum; endoplasmic reticulum membrane; endosome membrane; external side of plasma membrane; extracellular space; lysosomal membrane; lysosome; plasma membrane beta-2-microglobulin binding cell adhesion molecule binding endogenous lipid antigen binding exogenous lipid antigen binding histone binding lipid antigen binding lipopeptide binding Homo sapiens 3D-structure Cell membrane Disulfide bond Endoplasmic reticulum Endosome Glycoprotein Immunity Immunoglobulin domain Innate immunity Lysosome Membrane Reference proteome Signal Transmembrane Transmembrane helix MGCLLFLLLW MGCLLFLLLWALLQAWGSAEVPQRLFPLRCLQISSFANSSWTRTDGLAWLGELQTHSWSNDSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRLSYPLELQVSAGCEVHPGNASNNFFHVAFQGKDILSFQGTSWEPTQEAPLWVNLAIQVLNQDKWTRETVQWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFYPKPVWVKWMRGEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQDIVLYWGGSYTSMGLIALAVLACLLFLLIVGFTSRFKRQTSYQGVL |
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