Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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immune response immunoglobulin mediated immune response | endoplasmic reticulum; extracellular region; IgG immunoglobulin complex; membrane | antigen binding | Homo sapiens | 3D-structure Alternative splicing Disease variant Disulfide bond Endoplasmic reticulum Immunoglobulin domain Reference proteome Secreted Signal | MRPGTGQGGL | MRPGTGQGGLEAPGEPGPNLRQRWPLLLLGLAVVTHGLLRPTAASQSRALGPGAPGGSSRSSLRSRWGRFLLQRGSWTGPRCWPRGFQSKHNSVTHVFGSGTQLTVLSQPKATPSVTLFPPSSEELQANKATLVCLMNDFYPGILTVTWKADGTPITQGVEMTTPSKQSNNKYAASSYLSLTPEQWRSRRSYSCQVMHEGSTVEKTVAPAECS | immune response immunoglobulin mediated immune response endoplasmic reticulum; extracellular region; IgG immunoglobulin complex; membrane antigen binding Homo sapiens 3D-structure Alternative splicing Disease variant Disulfide bond Endoplasmic reticulum Immunoglobulin domain Reference proteome Secreted Signal MRPGTGQGGL MRPGTGQGGLEAPGEPGPNLRQRWPLLLLGLAVVTHGLLRPTAASQSRALGPGAPGGSSRSSLRSRWGRFLLQRGSWTGPRCWPRGFQSKHNSVTHVFGSGTQLTVLSQPKATPSVTLFPPSSEELQANKATLVCLMNDFYPGILTVTWKADGTPITQGVEMTTPSKQSNNKYAASSYLSLTPEQWRSRRSYSCQVMHEGSTVEKTVAPAECS |
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane suppression by virus of host tetherin activity suppression by virus of host type I interferon-mediated signaling pathway virion attachment to host cell | host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane | structural molecule activity | Human immunodeficiency virus type 2 subtype B | AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Inhibition of host tetherin by virus Lipoprotein Membrane Palmitate Signal Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Viral immunoevasion Viral penetration into host cytoplasm Virion Virus endocytosis by host Virus entry into host cell | MAYFSSRLPI | MAYFSSRLPIALLLIGISGFVCKQYVTVFYGIPAWRNATVPLICATTNRDTWGTVQCLPDNGDYTEIRLNITEAFDAWDNTVTQQAVDDVWRLFETSIKPCVKLTPLCVAMNCSKTETNPGNASSTTTTKPTTTSRGLKTINETDPCIKNDSCTGLGEEEIMQCNFSMTGLRRDELKQYKDTWYSEDLECNNTRKYTSRCYIRTCNTTIIQESCDKHYWDSLRFRYCAPPGFFLLRCNDTNYSGFMPNCSKVVASSCTRMMETQSSTWFGFNGTRAENRTYIYWHEKDNRTIISLNTYYNLSIHCKRPGNKTVVPIRTVSGLLFHSQPINKRPRQAWCWFKGNWTEAIKEVKRTIIKHPRYKGGAKNITSVKLVSEHGKGSDPETTYMWTNCRGEFLYCNMTWFLNWVENKTNTTRRNYAPCHIRQIINTWHKVGKNIYLPPREGELSCNSTVTSLIANINSDNSTTNISVSAEVSELYRLELGDYKLVEITPIGFAPTDVRRYSSVKPRNKRGVMVLGFLGFLAMAGSAMGATSLTLSAQSRTLLAGIVQQQQQPVDVVKRQQELLRLTVWGTKNLQARVTAIEKYLKDQAQLNSWGCAFRQVCHTTVPWPNETLTPNWNNMTWQQWEKQVHFLDANITALLEEAQIQQEKNMYELQKINSWDVFGNWFDLTSWIKYIHLGLYIVAGLVVLRIVVYIVQMLARLRKGYRPVFSSPPSYTQQIPIRKDRGQPANEETEEGGGNDGDYRSWPWQIEYIHFLLRQLRNLLIWLYNGCRTLLLKTFQILHQISTNLQPLRLPVAYLQYGISWFQEALRAAARATGETLASAGETLWEALRRAARAIIAIPRRIRQGLELTLL | clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane suppression by virus of host tetherin activity suppression by virus of host type I interferon-mediated signaling pathway virion attachment to host cell host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane structural molecule activity Human immunodeficiency virus type 2 subtype B AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Inhibition of host tetherin by virus Lipoprotein Membrane Palmitate Signal Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Viral immunoevasion Viral penetration into host cytoplasm Virion Virus endocytosis by host Virus entry into host cell MAYFSSRLPI MAYFSSRLPIALLLIGISGFVCKQYVTVFYGIPAWRNATVPLICATTNRDTWGTVQCLPDNGDYTEIRLNITEAFDAWDNTVTQQAVDDVWRLFETSIKPCVKLTPLCVAMNCSKTETNPGNASSTTTTKPTTTSRGLKTINETDPCIKNDSCTGLGEEEIMQCNFSMTGLRRDELKQYKDTWYSEDLECNNTRKYTSRCYIRTCNTTIIQESCDKHYWDSLRFRYCAPPGFFLLRCNDTNYSGFMPNCSKVVASSCTRMMETQSSTWFGFNGTRAENRTYIYWHEKDNRTIISLNTYYNLSIHCKRPGNKTVVPIRTVSGLLFHSQPINKRPRQAWCWFKGNWTEAIKEVKRTIIKHPRYKGGAKNITSVKLVSEHGKGSDPETTYMWTNCRGEFLYCNMTWFLNWVENKTNTTRRNYAPCHIRQIINTWHKVGKNIYLPPREGELSCNSTVTSLIANINSDNSTTNISVSAEVSELYRLELGDYKLVEITPIGFAPTDVRRYSSVKPRNKRGVMVLGFLGFLAMAGSAMGATSLTLSAQSRTLLAGIVQQQQQPVDVVKRQQELLRLTVWGTKNLQARVTAIEKYLKDQAQLNSWGCAFRQVCHTTVPWPNETLTPNWNNMTWQQWEKQVHFLDANITALLEEAQIQQEKNMYELQKINSWDVFGNWFDLTSWIKYIHLGLYIVAGLVVLRIVVYIVQMLARLRKGYRPVFSSPPSYTQQIPIRKDRGQPANEETEEGGGNDGDYRSWPWQIEYIHFLLRQLRNLLIWLYNGCRTLLLKTFQILHQISTNLQPLRLPVAYLQYGISWFQEALRAAARATGETLASAGETLWEALRRAARAIIAIPRRIRQGLELTLL |
viral budding via host ESCRT complex | host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane | RNA binding structural molecule activity zinc ion binding | Human immunodeficiency virus type 2 subtype B | AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Phosphoprotein Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucleoprotein Viral release from host cell Virion Zinc Zinc-finger | MGARGSVLSG | MGARGSVLSGKKTDELEKVRLRPGGKKKYMLKHVVWAVNELDRFGLAESLLESKEGCQKILKVLAPLVPTGSENLKSLFNIVCVIFCLHAEEKVKDTEEAKKIAQRHLAADTEKMPATNKPTAPPSGGNYPVQQLAGNYVHLPLSPRTLNAWVKLVEEKKFGAEVVPGFQALSEGCTPYDINQMLNCVGEHQAAMQIIREIINEEAADWDQQHPSPGPMPAGQLRDPRGSDIAGTTSTVEEQIQWMYRAQNPVPVGNIYRRWIQLGLQKCVRMYNPTNILDIKQGPKEPFQSYVDRFYKSLRAEQTDPAVKNWMTQTLLIQNANPDCKLVLKGLGMNPTLEEMLTACQGIGGPGQKARLMAEALKEALTPAPIPFAAVQQKAGKRGTVTCWNCGKQGHTARQCRAPRRQGCWKCGKTGHIMSKCPERQAGFLGLGPWGKKPRNFPMTQVPQGVTPSAPPMNPAEGMTPRGATPSAPPADPAVEMLKSYMQMGRQQRESRERPYKEVTEDLLHLNSLFGEDQ | viral budding via host ESCRT complex host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane RNA binding structural molecule activity zinc ion binding Human immunodeficiency virus type 2 subtype B AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Phosphoprotein Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucleoprotein Viral release from host cell Virion Zinc Zinc-finger MGARGSVLSG MGARGSVLSGKKTDELEKVRLRPGGKKKYMLKHVVWAVNELDRFGLAESLLESKEGCQKILKVLAPLVPTGSENLKSLFNIVCVIFCLHAEEKVKDTEEAKKIAQRHLAADTEKMPATNKPTAPPSGGNYPVQQLAGNYVHLPLSPRTLNAWVKLVEEKKFGAEVVPGFQALSEGCTPYDINQMLNCVGEHQAAMQIIREIINEEAADWDQQHPSPGPMPAGQLRDPRGSDIAGTTSTVEEQIQWMYRAQNPVPVGNIYRRWIQLGLQKCVRMYNPTNILDIKQGPKEPFQSYVDRFYKSLRAEQTDPAVKNWMTQTLLIQNANPDCKLVLKGLGMNPTLEEMLTACQGIGGPGQKARLMAEALKEALTPAPIPFAAVQQKAGKRGTVTCWNCGKQGHTARQCRAPRRQGCWKCGKTGHIMSKCPERQAGFLGLGPWGKKPRNFPMTQVPQGVTPSAPPMNPAEGMTPRGATPSAPPADPAVEMLKSYMQMGRQQRESRERPYKEVTEDLLHLNSLFGEDQ |
autophagy colon epithelial cell migration lysosomal transport lysosome organization positive regulation of neuron projection development regulation of epithelial cell migration response to estrogen response to methylmercury response to nutrient response to pH | azurophil granule lumen; cell surface; endoplasmic reticulum lumen; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; lysosomal lumen; lysosome | arylsulfatase activity metal ion binding N-acetylgalactosamine-4-sulfatase activity | Homo sapiens | 3D-structure Alternative splicing Calcium Direct protein sequencing Disease variant Disulfide bond Glycoprotein Hydrolase Ichthyosis Leukodystrophy Lysosome Metachromatic leukodystrophy Metal-binding Mucopolysaccharidosis Reference proteome Signal | MGPRGAASLP | MGPRGAASLPRGPGPRRLLLPVVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLPEYSAFNTSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDRDPEERHDLSREYPHIVTKLLSRLQFYHKHSVPVYFPAQDPRCDPKATGVWGPWM | autophagy colon epithelial cell migration lysosomal transport lysosome organization positive regulation of neuron projection development regulation of epithelial cell migration response to estrogen response to methylmercury response to nutrient response to pH azurophil granule lumen; cell surface; endoplasmic reticulum lumen; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; lysosomal lumen; lysosome arylsulfatase activity metal ion binding N-acetylgalactosamine-4-sulfatase activity Homo sapiens 3D-structure Alternative splicing Calcium Direct protein sequencing Disease variant Disulfide bond Glycoprotein Hydrolase Ichthyosis Leukodystrophy Lysosome Metachromatic leukodystrophy Metal-binding Mucopolysaccharidosis Reference proteome Signal MGPRGAASLP MGPRGAASLPRGPGPRRLLLPVVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLPEYSAFNTSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDRDPEERHDLSREYPHIVTKLLSRLQFYHKHSVPVYFPAQDPRCDPKATGVWGPWM |
anatomical structure development regulation of transcription by RNA polymerase II skeletal system development transcription by RNA polymerase II | chromatin; nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Homo sapiens | Activator Alternative splicing Deafness Developmental protein Disease variant DNA-binding Intellectual disability Nucleus Paired box Reference proteome Transcription Transcription regulation | MKFTLGLGSR | MKFTLGLGSRAWRVSWEGAAAAAAGPGAGGSALRCRAQRVSSPRLGRRGSRLSGALPLCLSRGGGGAQALPDCAGPSPGHPGHPGARQLAGPLAMEQTYGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPNVVKHIRDYKQGDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNKIGSLAQPGPYEASKQPPSQPTLPYNHIYQYPYPSPVSPTGAKMGSHPGVPGTAGHVSIPRSWPSAHSVSNILGIRTFMEQTGALAGSEGTAYSPKMEDWAGVNRTAFPATPAVNGLEKPALEADIKYTQSASTLSAVGGFLPACAYPASNQHGVYSAPGGGYLAPGPPWPPAQGPPLAPPGAGVAVHGGELAAAMTFKHPSREGSLPAPAARPRTPSVAYTDCPSRPRPPRGSSPRTRARRERQADPGAQVCAAAPAIGTGRIGGLAEEEASAGPRGARPASPQAQPCLWPDPPHFLYWSGFLGFSELGF | anatomical structure development regulation of transcription by RNA polymerase II skeletal system development transcription by RNA polymerase II chromatin; nucleus DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding Homo sapiens Activator Alternative splicing Deafness Developmental protein Disease variant DNA-binding Intellectual disability Nucleus Paired box Reference proteome Transcription Transcription regulation MKFTLGLGSR MKFTLGLGSRAWRVSWEGAAAAAAGPGAGGSALRCRAQRVSSPRLGRRGSRLSGALPLCLSRGGGGAQALPDCAGPSPGHPGHPGARQLAGPLAMEQTYGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPNVVKHIRDYKQGDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNKIGSLAQPGPYEASKQPPSQPTLPYNHIYQYPYPSPVSPTGAKMGSHPGVPGTAGHVSIPRSWPSAHSVSNILGIRTFMEQTGALAGSEGTAYSPKMEDWAGVNRTAFPATPAVNGLEKPALEADIKYTQSASTLSAVGGFLPACAYPASNQHGVYSAPGGGYLAPGPPWPPAQGPPLAPPGAGVAVHGGELAAAMTFKHPSREGSLPAPAARPRTPSVAYTDCPSRPRPPRGSSPRTRARRERQADPGAQVCAAAPAIGTGRIGGLAEEEASAGPRGARPASPQAQPCLWPDPPHFLYWSGFLGFSELGF |
chromatin organization chromosome condensation negative regulation of DNA recombination negative regulation of transcription by RNA polymerase II nucleosome assembly regulation of transcription by RNA polymerase II | euchromatin; nucleosome; nucleus | chromatin DNA binding DNA binding double-stranded DNA binding nucleosomal DNA binding structural constituent of chromatin | Mus musculus | Acetylation ADP-ribosylation Chromosome Citrullination DNA-binding Hydroxylation Methylation Nucleus Phosphoprotein Reference proteome | MSEAAPAAPA | MSEAAPAAPAAAPPAEKAPAKKKAAKKPAGVRRKASGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGILVQTKGTGASGSFKLNKKAASGEAKPQAKKAGAAKAKKPAGAAKKPKKATGAATPKKAAKKTPKKAKKPAAAAVTKKVAKSPKKAKVTKPKKVKSASKAVKPKAAKPKVAKAKKVAAKKK | chromatin organization chromosome condensation negative regulation of DNA recombination negative regulation of transcription by RNA polymerase II nucleosome assembly regulation of transcription by RNA polymerase II euchromatin; nucleosome; nucleus chromatin DNA binding DNA binding double-stranded DNA binding nucleosomal DNA binding structural constituent of chromatin Mus musculus Acetylation ADP-ribosylation Chromosome Citrullination DNA-binding Hydroxylation Methylation Nucleus Phosphoprotein Reference proteome MSEAAPAAPA MSEAAPAAPAAAPPAEKAPAKKKAAKKPAGVRRKASGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGILVQTKGTGASGSFKLNKKAASGEAKPQAKKAGAAKAKKPAGAAKKPKKATGAATPKKAAKKTPKKAKKPAAAAVTKKVAKSPKKAKVTKPKKVKSASKAVKPKAAKPKVAKAKKVAAKKK |
chromatin organization chromosome condensation negative regulation of DNA recombination negative regulation of transcription by RNA polymerase II nucleosome assembly regulation of transcription by RNA polymerase II | chromatin; heterochromatin; nucleosome; nucleus | ADP binding AMP binding ATP binding calcium ion binding chromatin DNA binding dATP binding DNA binding double-stranded DNA binding GTP binding histone deacetylase binding nucleosomal DNA binding nucleotide binding structural constituent of chromatin | Rattus norvegicus | Acetylation ADP-ribosylation Chromosome Citrullination Direct protein sequencing DNA-binding Hydroxylation Methylation Nucleus Phosphoprotein Reference proteome | MSETAPAAPA | MSETAPAAPAAPAPAEKTPIKKKARKAAGGAKRKASGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKAKKAGAAKAKKPAGAAKKPKKATGTATPKKSTKKTPKKAKKPAAAAGAKKAKSPKKAKATKAKKAPKSPAKARAVKPKAAKPKTSKPKAAKPKKTAAKKK | chromatin organization chromosome condensation negative regulation of DNA recombination negative regulation of transcription by RNA polymerase II nucleosome assembly regulation of transcription by RNA polymerase II chromatin; heterochromatin; nucleosome; nucleus ADP binding AMP binding ATP binding calcium ion binding chromatin DNA binding dATP binding DNA binding double-stranded DNA binding GTP binding histone deacetylase binding nucleosomal DNA binding nucleotide binding structural constituent of chromatin Rattus norvegicus Acetylation ADP-ribosylation Chromosome Citrullination Direct protein sequencing DNA-binding Hydroxylation Methylation Nucleus Phosphoprotein Reference proteome MSETAPAAPA MSETAPAAPAAPAPAEKTPIKKKARKAAGGAKRKASGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKAKKAGAAKAKKPAGAAKKPKKATGTATPKKSTKKTPKKAKKPAAAAGAKKAKSPKKAKATKAKKAPKSPAKARAVKPKAAKPKTSKPKAAKPKKTAAKKK |
error-free translesion synthesis establishment of mitotic sister chromatid cohesion lagging strand elongation leading strand elongation maintenance of DNA trinucleotide repeats meiotic mismatch repair mismatch repair mitotic cell cycle mitotic sister chromatid cohesion nucleotide-excision repair positive regulation of DNA metabolic process positive regulation of DNA repair positive regulation of DNA replication postreplication repair silent mating-type cassette heterochromatin formation subtelomeric heterochromatin formation translesion synthesis | chromosome, telomeric region; nucleus; PCNA complex; replication fork | DNA binding DNA polymerase processivity factor activity identical protein binding | Saccharomyces cerevisiae | 3D-structure Direct protein sequencing DNA damage DNA repair DNA replication DNA-binding Isopeptide bond Nucleus Reference proteome Ubl conjugation | MLEAKFEEAS | MLEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQEYRCDHPVTLGMDLTSLSKILRCGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLKLMDIDADFLKIEELQYDSTLSLPSSEFSKIVRDLSQLSDSINIMITKETIKFVADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFDLKSGFLQFFLAPKFNDEE | error-free translesion synthesis establishment of mitotic sister chromatid cohesion lagging strand elongation leading strand elongation maintenance of DNA trinucleotide repeats meiotic mismatch repair mismatch repair mitotic cell cycle mitotic sister chromatid cohesion nucleotide-excision repair positive regulation of DNA metabolic process positive regulation of DNA repair positive regulation of DNA replication postreplication repair silent mating-type cassette heterochromatin formation subtelomeric heterochromatin formation translesion synthesis chromosome, telomeric region; nucleus; PCNA complex; replication fork DNA binding DNA polymerase processivity factor activity identical protein binding Saccharomyces cerevisiae 3D-structure Direct protein sequencing DNA damage DNA repair DNA replication DNA-binding Isopeptide bond Nucleus Reference proteome Ubl conjugation MLEAKFEEAS MLEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQEYRCDHPVTLGMDLTSLSKILRCGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLKLMDIDADFLKIEELQYDSTLSLPSSEFSKIVRDLSQLSDSINIMITKETIKFVADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFDLKSGFLQFFLAPKFNDEE |
leucine biosynthetic process | cytosol | 2-isopropylmalate synthase activity acetyl-CoA C-acetyltransferase activity manganese ion binding | Salmonella typhimurium | Amino-acid biosynthesis Branched-chain amino acid biosynthesis Cytoplasm Direct protein sequencing Leucine biosynthesis Manganese Metal-binding Reference proteome Transferase | MSQQVIIFDT | MSQQVIIFDTTLRDGEQALQASLSAKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQTIARTIKNSRVCALARCVEKDIDVAAQALKVADAFRIHTFIATSPMHIATKLRSTLDEVIERAVYMVKRARNYTDDVEFSCEDAGRTPVDDLARVVEAAINAGARTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGIAVGNSLAAVHAGARQVEGAMNGIGERAGNCALEEVIMAIKVRKDIMNVHTNINHHEIWRTSQTVSQICNMPIPANKAIVGSGAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGRAAVKHRMEEMGYKDTDYNMDHLYDAFLKLADKKGQVFDYDLEALAFINKQQEEPEHFRLDYFSVQSGSSDIATASVKLACGEEIKAEAANGNGPVDAIYQAINRITGYDVELVKYDLNAKGQGKDALGQVDIVVNHHGRRFHGVGLATDIVESSAKAMVHVLNNIWRAAEVEKELQRKAQNKENNKETV | leucine biosynthetic process cytosol 2-isopropylmalate synthase activity acetyl-CoA C-acetyltransferase activity manganese ion binding Salmonella typhimurium Amino-acid biosynthesis Branched-chain amino acid biosynthesis Cytoplasm Direct protein sequencing Leucine biosynthesis Manganese Metal-binding Reference proteome Transferase MSQQVIIFDT MSQQVIIFDTTLRDGEQALQASLSAKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQTIARTIKNSRVCALARCVEKDIDVAAQALKVADAFRIHTFIATSPMHIATKLRSTLDEVIERAVYMVKRARNYTDDVEFSCEDAGRTPVDDLARVVEAAINAGARTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGIAVGNSLAAVHAGARQVEGAMNGIGERAGNCALEEVIMAIKVRKDIMNVHTNINHHEIWRTSQTVSQICNMPIPANKAIVGSGAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGRAAVKHRMEEMGYKDTDYNMDHLYDAFLKLADKKGQVFDYDLEALAFINKQQEEPEHFRLDYFSVQSGSSDIATASVKLACGEEIKAEAANGNGPVDAIYQAINRITGYDVELVKYDLNAKGQGKDALGQVDIVVNHHGRRFHGVGLATDIVESSAKAMVHVLNNIWRAAEVEKELQRKAQNKENNKETV |
cytoplasmic translation positive regulation of ubiquitin-protein transferase activity translation | cytoplasm; cytosol; cytosolic ribosome; cytosolic small ribosomal subunit; extracellular exosome; focal adhesion; membrane; nucleoplasm; nucleus | cadherin binding enzyme binding fibroblast growth factor binding mRNA binding RNA binding structural constituent of ribosome | Homo sapiens | 3D-structure Acetylation Citrullination Cytoplasm Direct protein sequencing Isopeptide bond Nucleus Phosphoprotein Reference proteome Repeat Ribonucleoprotein Ribosomal protein Ubl conjugation | MADDAGAAGG | MADDAGAAGGPGGPGGPGMGNRGGFRGGFGSGIRGRGRGRGRGRGRGRGARGGKAEDKEWMPVTKLGRLVKDMKIKSLEEIYLFSLPIKESEIIDFFLGASLKDEVLKIMPVQKQTRAGQRTRFKAFVAIGDYNGHVGLGVKCSKEVATAIRGAIILAKLSIVPVRRGYWGNKIGKPHTVPCKVTGRCGSVLVRLIPAPRGTGIVSAPVPKKLLMMAGIDDCYTSARGCTATLGNFAKATFDAISKTYSYLTPDLWKETVFTKSPYQEFTDHLVKTHTRVSVQRTQAPAVATT | cytoplasmic translation positive regulation of ubiquitin-protein transferase activity translation cytoplasm; cytosol; cytosolic ribosome; cytosolic small ribosomal subunit; extracellular exosome; focal adhesion; membrane; nucleoplasm; nucleus cadherin binding enzyme binding fibroblast growth factor binding mRNA binding RNA binding structural constituent of ribosome Homo sapiens 3D-structure Acetylation Citrullination Cytoplasm Direct protein sequencing Isopeptide bond Nucleus Phosphoprotein Reference proteome Repeat Ribonucleoprotein Ribosomal protein Ubl conjugation MADDAGAAGG MADDAGAAGGPGGPGGPGMGNRGGFRGGFGSGIRGRGRGRGRGRGRGRGARGGKAEDKEWMPVTKLGRLVKDMKIKSLEEIYLFSLPIKESEIIDFFLGASLKDEVLKIMPVQKQTRAGQRTRFKAFVAIGDYNGHVGLGVKCSKEVATAIRGAIILAKLSIVPVRRGYWGNKIGKPHTVPCKVTGRCGSVLVRLIPAPRGTGIVSAPVPKKLLMMAGIDDCYTSARGCTATLGNFAKATFDAISKTYSYLTPDLWKETVFTKSPYQEFTDHLVKTHTRVSVQRTQAPAVATT |
ephrin receptor signaling pathway motor neuron axon guidance regulation of axonogenesis regulation of small GTPase mediated signal transduction | cytosol | ephrin receptor binding GTPase activator activity metal ion binding | Homo sapiens | 3D-structure Acetylation Alternative splicing Disease variant GTPase activation Metal-binding Neurogenesis Phosphoprotein Reference proteome SH2 domain Zinc Zinc-finger | MALTLFDTDE | MALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREAADQLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKETHDERDSTGQDGVSEKRLTSLVRRATLKENEQIPKYEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF | ephrin receptor signaling pathway motor neuron axon guidance regulation of axonogenesis regulation of small GTPase mediated signal transduction cytosol ephrin receptor binding GTPase activator activity metal ion binding Homo sapiens 3D-structure Acetylation Alternative splicing Disease variant GTPase activation Metal-binding Neurogenesis Phosphoprotein Reference proteome SH2 domain Zinc Zinc-finger MALTLFDTDE MALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREAADQLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKETHDERDSTGQDGVSEKRLTSLVRRATLKENEQIPKYEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF |
cell differentiation nervous system development positive regulation of DNA-templated transcription positive regulation of neuron differentiation positive regulation of transcription by RNA polymerase II protein-DNA complex assembly regulation of transcription by RNA polymerase II | beta-catenin-TCF complex; beta-catenin-TCF7L2 complex; chromatin; nucleus; transcription regulator complex | beta-catenin binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific E-box binding identical protein binding protein heterodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding TFIIB-class transcription factor binding | Homo sapiens | 3D-structure Activator Alternative splicing Corneal dystrophy Differentiation Disease variant DNA-binding Epilepsy Intellectual disability Neurogenesis Nucleus Phosphoprotein Primary microcephaly Reference proteome Transcription Transcription regulation | MHHQQRMAAL | MHHQQRMAALGTDKELSDLLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLMVGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITSNNDDEDLTPEQKAEREKERRMANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM | cell differentiation nervous system development positive regulation of DNA-templated transcription positive regulation of neuron differentiation positive regulation of transcription by RNA polymerase II protein-DNA complex assembly regulation of transcription by RNA polymerase II beta-catenin-TCF complex; beta-catenin-TCF7L2 complex; chromatin; nucleus; transcription regulator complex beta-catenin binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific E-box binding identical protein binding protein heterodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding TFIIB-class transcription factor binding Homo sapiens 3D-structure Activator Alternative splicing Corneal dystrophy Differentiation Disease variant DNA-binding Epilepsy Intellectual disability Neurogenesis Nucleus Phosphoprotein Primary microcephaly Reference proteome Transcription Transcription regulation MHHQQRMAAL MHHQQRMAALGTDKELSDLLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLMVGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITSNNDDEDLTPEQKAEREKERRMANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM |
actin cortical patch assembly barbed-end actin filament capping positive regulation of Arp2/3 complex-mediated actin nucleation protein localization to actin cortical patch regulation of actin filament polymerization | actin cortical patch; cell cortex; cortical actin cytoskeleton; cytoplasm; mating projection tip; site of polarized growth | actin filament binding | Saccharomyces cerevisiae | 3D-structure Acetylation Actin-binding Cytoplasm Cytoskeleton Direct protein sequencing Isopeptide bond Phosphoprotein Reference proteome Repeat SH3 domain Ubl conjugation | MALEPIDYTT | MALEPIDYTTHSREIDAEYLKIVRGSDPDTTWLIISPNAKKEYEPESTGSSFHDFLQLFDETKVQYGLARVSPPGSDVEKIIIIGWCPDSAPLKTRASFAANFAAVANNLFKGYHVQVTARDEDDLDENELLMKISNAAGARYSIQTSSKQQGKASTPPVKKSFTPSKSPAPVSKKEPVKTPSPAPAAKISSRVNDNNDDDDWNEPELKERDFDQAPLKPNQSSYKPIGKIDLQKVIAEEKAKEDPRLVQKPTAAGSKIDPSSDIANLKNESKLKRDSEFNSFLGTTKPPSMTESSLKNDDDKVIKGFRNEKSPAQLWAERKAKQNSGNAETKAEAPKPEVPEDEPEGEPDVKDLKSKFEGLAASEKEEEEMENKFAPPPKKSEPTIISPKPFSKPQEPVKAEEAEQPKTDYKKIGNPLPGMHIEADNEEEPEENDDDWDDDEDEAAQPPLPSRNVASGAPVQKEEPEQEEIAPSLPSRNSIPAPKQEEAPEQAPEEEIEEEAEEAAPQLPSRSSAAPPPPPRRATPEKKPKENPWATAEYDYDAAEDNELTFVENDKIINIEFVDDDWWLGELEKDGSKGLFPSNYVSLGN | actin cortical patch assembly barbed-end actin filament capping positive regulation of Arp2/3 complex-mediated actin nucleation protein localization to actin cortical patch regulation of actin filament polymerization actin cortical patch; cell cortex; cortical actin cytoskeleton; cytoplasm; mating projection tip; site of polarized growth actin filament binding Saccharomyces cerevisiae 3D-structure Acetylation Actin-binding Cytoplasm Cytoskeleton Direct protein sequencing Isopeptide bond Phosphoprotein Reference proteome Repeat SH3 domain Ubl conjugation MALEPIDYTT MALEPIDYTTHSREIDAEYLKIVRGSDPDTTWLIISPNAKKEYEPESTGSSFHDFLQLFDETKVQYGLARVSPPGSDVEKIIIIGWCPDSAPLKTRASFAANFAAVANNLFKGYHVQVTARDEDDLDENELLMKISNAAGARYSIQTSSKQQGKASTPPVKKSFTPSKSPAPVSKKEPVKTPSPAPAAKISSRVNDNNDDDDWNEPELKERDFDQAPLKPNQSSYKPIGKIDLQKVIAEEKAKEDPRLVQKPTAAGSKIDPSSDIANLKNESKLKRDSEFNSFLGTTKPPSMTESSLKNDDDKVIKGFRNEKSPAQLWAERKAKQNSGNAETKAEAPKPEVPEDEPEGEPDVKDLKSKFEGLAASEKEEEEMENKFAPPPKKSEPTIISPKPFSKPQEPVKAEEAEQPKTDYKKIGNPLPGMHIEADNEEEPEENDDDWDDDEDEAAQPPLPSRNVASGAPVQKEEPEQEEIAPSLPSRNSIPAPKQEEAPEQAPEEEIEEEAEEAAPQLPSRSSAAPPPPPRRATPEKKPKENPWATAEYDYDAAEDNELTFVENDKIINIEFVDDDWWLGELEKDGSKGLFPSNYVSLGN |
humoral immune response N-acetylneuraminate metabolic process negative regulation of chemotaxis negative regulation of macrophage apoptotic process O-glycan processing positive regulation of mononuclear cell proliferation protein N-linked glycosylation via asparagine regulation of substrate adhesion-dependent cell spreading response to ethanol sialylation viral protein processing | extracellular region; Golgi apparatus; Golgi cisterna membrane; Golgi medial cisterna; Golgi membrane; Golgi trans cisterna | beta-galactoside alpha-2,6-sialyltransferase activity protein homodimerization activity sialyltransferase activity | Homo sapiens | 3D-structure Alternative splicing Disulfide bond Glycoprotein Glycosyltransferase Golgi apparatus Membrane Phosphoprotein Reference proteome Secreted Signal-anchor Transferase Transmembrane Transmembrane helix | MIHTNLKKKF | MIHTNLKKKFSCCVLVFLLFAVICVWKEKKKGSYYDSFKLQTKEFQVLKSLGKLAMGSDSQSVSSSSTQDPHRGRQTLGSLRGLAKAKPEASFQVWNKDSSSKNLIPRLQKIWKNYLSMNKYKVSYKGPGPGIKFSAEALRCHLRDHVNVSMVEVTDFPFNTSEWEGYLPKESIRTKAGPWGRCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQLVTTEKRFLKDSLYNEGILIVWDPSVYHSDIPKWYQNPDYNFFNNYKTYRKLHPNQPFYILKPQMPWELWDILQEISPEEIQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKTDVCYYYQKFFDSACTMGAYHPLLYEKNLVKHLNQGTDEDIYLLGKATLPGFRTIHC | humoral immune response N-acetylneuraminate metabolic process negative regulation of chemotaxis negative regulation of macrophage apoptotic process O-glycan processing positive regulation of mononuclear cell proliferation protein N-linked glycosylation via asparagine regulation of substrate adhesion-dependent cell spreading response to ethanol sialylation viral protein processing extracellular region; Golgi apparatus; Golgi cisterna membrane; Golgi medial cisterna; Golgi membrane; Golgi trans cisterna beta-galactoside alpha-2,6-sialyltransferase activity protein homodimerization activity sialyltransferase activity Homo sapiens 3D-structure Alternative splicing Disulfide bond Glycoprotein Glycosyltransferase Golgi apparatus Membrane Phosphoprotein Reference proteome Secreted Signal-anchor Transferase Transmembrane Transmembrane helix MIHTNLKKKF MIHTNLKKKFSCCVLVFLLFAVICVWKEKKKGSYYDSFKLQTKEFQVLKSLGKLAMGSDSQSVSSSSTQDPHRGRQTLGSLRGLAKAKPEASFQVWNKDSSSKNLIPRLQKIWKNYLSMNKYKVSYKGPGPGIKFSAEALRCHLRDHVNVSMVEVTDFPFNTSEWEGYLPKESIRTKAGPWGRCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQLVTTEKRFLKDSLYNEGILIVWDPSVYHSDIPKWYQNPDYNFFNNYKTYRKLHPNQPFYILKPQMPWELWDILQEISPEEIQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKTDVCYYYQKFFDSACTMGAYHPLLYEKNLVKHLNQGTDEDIYLLGKATLPGFRTIHC |
proteolysis | extracellular region; host cell cytosol | metalloendopeptidase activity metallopeptidase activity toxin activity zinc ion binding | Bacillus anthracis | 3D-structure Direct protein sequencing Host cytoplasm Hydrolase Metal-binding Metalloprotease Plasmid Protease Reference proteome Repeat Secreted Signal Toxin Virulence Zinc | MNIKKEFIKV | MNIKKEFIKVISMSCLVTAITLSGPVFIPLVQGAGGHGDVGMHVKEKEKNKDENKRKDEERNKTQEEHLKEIMKHIVKIEVKGEEAVKKEAAEKLLEKVPSDVLEMYKAIGGKIYIVDGDITKHISLEALSEDKKKIKDIYGKDALLHEHYVYAKEGYEPVLVIQSSEDYVENTEKALNVYYEIGKILSRDILSKINQPYQKFLDVLNTIKNASDSDGQDLLFTNQLKEHPTDFSVEFLEQNSNEVQEVFAKAFAYYIEPQHRDVLQLYAPEAFNYMDKFNEQEINLSLEELKDQRMLARYEKWEKIKQHYQHWSDSLSEEGRGLLKKLQIPIEPKKDDIIHSLSQEEKELLKRIQIDSSDFLSTEEKEFLKKLQIDIRDSLSEEEKELLNRIQVDSSNPLSEKEKEFLKKLKLDIQPYDINQRLQDTGGLIDSPSINLDVRKQYKRDIQNIDALLHQSIGSTLYNKIYLYENMNINNLTATLGADLVDSTDNTKINRGIFNEFKKNFKYSISSNYMIVDINERPALDNERLKWRIQLSPDTRAGYLENGKLILQRNIGLEIKDVQIIKQSEKEYIRIDAKVVPKSKIDTKIQEAQLNINQEWNKALGLPKYTKLITFNVHNRYASNIVESAYLILNEWKNNIQSDLIKKVTNYLVDGNGRFVFTDITLPNIAEQYTHQDEIYEQVHSKGLYVPESRSILLHGPSKGVELRNDSEGFIHEFGHAVDDYAGYLLDKNQSDLVTNSKKFIDIFKEEGSNLTSYGRTNEAEFFAEAFRLMHSTDHAERLKVQKNAPKTFQFINDQIKFIINS | proteolysis extracellular region; host cell cytosol metalloendopeptidase activity metallopeptidase activity toxin activity zinc ion binding Bacillus anthracis3D-structure Direct protein sequencing Host cytoplasm Hydrolase Metal-binding Metalloprotease Plasmid Protease Reference proteome Repeat Secreted Signal Toxin Virulence Zinc MNIKKEFIKV MNIKKEFIKVISMSCLVTAITLSGPVFIPLVQGAGGHGDVGMHVKEKEKNKDENKRKDEERNKTQEEHLKEIMKHIVKIEVKGEEAVKKEAAEKLLEKVPSDVLEMYKAIGGKIYIVDGDITKHISLEALSEDKKKIKDIYGKDALLHEHYVYAKEGYEPVLVIQSSEDYVENTEKALNVYYEIGKILSRDILSKINQPYQKFLDVLNTIKNASDSDGQDLLFTNQLKEHPTDFSVEFLEQNSNEVQEVFAKAFAYYIEPQHRDVLQLYAPEAFNYMDKFNEQEINLSLEELKDQRMLARYEKWEKIKQHYQHWSDSLSEEGRGLLKKLQIPIEPKKDDIIHSLSQEEKELLKRIQIDSSDFLSTEEKEFLKKLQIDIRDSLSEEEKELLNRIQVDSSNPLSEKEKEFLKKLKLDIQPYDINQRLQDTGGLIDSPSINLDVRKQYKRDIQNIDALLHQSIGSTLYNKIYLYENMNINNLTATLGADLVDSTDNTKINRGIFNEFKKNFKYSISSNYMIVDINERPALDNERLKWRIQLSPDTRAGYLENGKLILQRNIGLEIKDVQIIKQSEKEYIRIDAKVVPKSKIDTKIQEAQLNINQEWNKALGLPKYTKLITFNVHNRYASNIVESAYLILNEWKNNIQSDLIKKVTNYLVDGNGRFVFTDITLPNIAEQYTHQDEIYEQVHSKGLYVPESRSILLHGPSKGVELRNDSEGFIHEFGHAVDDYAGYLLDKNQSDLVTNSKKFIDIFKEEGSNLTSYGRTNEAEFFAEAFRLMHSTDHAERLKVQKNAPKTFQFINDQIKFIINS |
cellular response to increased oxygen levels intracellular iron ion homeostasis vacuolar acidification | acrosomal vesicle; endosome membrane; focal adhesion; intracellular membrane-bounded organelle; intracellular organelle; perinuclear region of cytoplasm; plasma membrane; proton-transporting V-type ATPase complex; proton-transporting V-type ATPase, V0 domain; transmembrane transporter complex; vacuolar proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase, V0 domain | ATPase binding proton-transporting ATPase activity, rotational mechanism | Mus musculus | 3D-structure Alternative splicing Cell membrane Endosome Hydrogen ion transport Ion transport Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport | MGSLFRSESM | MGSLFRSESMCLAQLFLQSGTAYECLSALGEKGLVQFRDLNQNVSSFQRKFVGEVKRCEELERILVYLVQEITRADIPLPEGEASPPAPPLKHVLEMQEQLQKLEVELREVTKNKEKLRKNLLELVEYTHMLRVTKTFLKRNVEFEPTYEEFPALENDSLLDYSCMQRLGAKLGFVSGLIQQGRVEAFERMLWRACKGYTIVTYAELDECLEDPETGEVIKWYVFLISFWGEQIGHKVKKICDCYHCHIYPYPNTAEERREIQEGLNTRIQDLYTVLHKTEDYLRQVLCKAAESVCSRVVQVRKMKAIYHMLNMCSFDVTNKCLIAEVWCPEVDLPGLRRALEEGSRESGATIPSFMNTIPTKETPPTLIRTNKFTEGFQNIVDAYGVGSYREVNPALFTIITFPFLFAVMFGDFGHGFVMFLFALLLVLNENHPRLSQSQEILRMFFDGRYILLLMGLFSVYTGLIYNDCFSKSVNLFGSGWNVSAMYSSSHSPEEQRKMVLWNDSTIRHSRTLQLDPNIPGVFRGPYPFGIDPIWNLATNRLTFLNSFKMKMSVILGIFHMTFGVVLGIFNHLHFRKKFNVYLVSVPEILFMLCIFGYLIFMIIYKWLAYSAETSREAPSILIEFINMFLFPTSKTHGLYPGQAHVQRVLVALTVLAVPVLFLGKPLFLLWLHNGRNCFGMSRSGYTLVRKDSEEEVSLLGNQDIEEGNSRMEEGCREVTCEEFNFGEILMTQAIHSIEYCLGCISNTASYLRLWALSLAHAQLSDVLWAMLMRVGLRVDTTYGVLLLLPVMAFFAVLTIFILLVMEGLSAFLHAIRLHWVEFQNKFYVGAGTKFVPFSFSLLSSKFSNDDSIA | cellular response to increased oxygen levels intracellular iron ion homeostasis vacuolar acidification acrosomal vesicle; endosome membrane; focal adhesion; intracellular membrane-bounded organelle; intracellular organelle; perinuclear region of cytoplasm; plasma membrane; proton-transporting V-type ATPase complex; proton-transporting V-type ATPase, V0 domain; transmembrane transporter complex; vacuolar proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase, V0 domain ATPase binding proton-transporting ATPase activity, rotational mechanism Mus musculus 3D-structure Alternative splicing Cell membrane Endosome Hydrogen ion transport Ion transport Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport MGSLFRSESM MGSLFRSESMCLAQLFLQSGTAYECLSALGEKGLVQFRDLNQNVSSFQRKFVGEVKRCEELERILVYLVQEITRADIPLPEGEASPPAPPLKHVLEMQEQLQKLEVELREVTKNKEKLRKNLLELVEYTHMLRVTKTFLKRNVEFEPTYEEFPALENDSLLDYSCMQRLGAKLGFVSGLIQQGRVEAFERMLWRACKGYTIVTYAELDECLEDPETGEVIKWYVFLISFWGEQIGHKVKKICDCYHCHIYPYPNTAEERREIQEGLNTRIQDLYTVLHKTEDYLRQVLCKAAESVCSRVVQVRKMKAIYHMLNMCSFDVTNKCLIAEVWCPEVDLPGLRRALEEGSRESGATIPSFMNTIPTKETPPTLIRTNKFTEGFQNIVDAYGVGSYREVNPALFTIITFPFLFAVMFGDFGHGFVMFLFALLLVLNENHPRLSQSQEILRMFFDGRYILLLMGLFSVYTGLIYNDCFSKSVNLFGSGWNVSAMYSSSHSPEEQRKMVLWNDSTIRHSRTLQLDPNIPGVFRGPYPFGIDPIWNLATNRLTFLNSFKMKMSVILGIFHMTFGVVLGIFNHLHFRKKFNVYLVSVPEILFMLCIFGYLIFMIIYKWLAYSAETSREAPSILIEFINMFLFPTSKTHGLYPGQAHVQRVLVALTVLAVPVLFLGKPLFLLWLHNGRNCFGMSRSGYTLVRKDSEEEVSLLGNQDIEEGNSRMEEGCREVTCEEFNFGEILMTQAIHSIEYCLGCISNTASYLRLWALSLAHAQLSDVLWAMLMRVGLRVDTTYGVLLLLPVMAFFAVLTIFILLVMEGLSAFLHAIRLHWVEFQNKFYVGAGTKFVPFSFSLLSSKFSNDDSIA |
B cell differentiation B cell lineage commitment immunoglobulin V(D)J recombination negative regulation of transcription by RNA polymerase II nervous system development positive regulation of B cell proliferation positive regulation of cell cycle positive regulation of DNA-binding transcription factor activity positive regulation of DNA-templated transcription positive regulation of neuron differentiation positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of G1/S transition of mitotic cell cycle regulation of transcription by RNA polymerase II | chromatin; cytoplasm; euchromatin; nucleoplasm; nucleus; protein-containing complex; RNA polymerase II transcription regulator complex; transcription regulator complex | bHLH transcription factor binding cis-regulatory region sequence-specific DNA binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor binding DNA-binding transcription repressor activity, RNA polymerase II-specific E-box binding mitogen-activated protein kinase kinase kinase binding protein heterodimerization activity protein homodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II-specific DNA-binding transcription factor binding vitamin D response element binding | Homo sapiens | 3D-structure Alternative splicing Chromosomal rearrangement Differentiation Disease variant DNA-binding Isopeptide bond Methylation Neurogenesis Nucleus Phosphoprotein Proto-oncogene Reference proteome Transcription Transcription regulation Ubl conjugation | MNQPQRMAPV | MNQPQRMAPVGTDKELSDLLDFSMMFPLPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSLSSSTFLGPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGRHAGLVGGSHPEDGLAGSTSLMHNHAALPSQPGTLPDLSRPPDSYSGLGRAGATAAASEIKREEKEDEENTSAADHSEEEKKELKAPRARTSPDEDEDDLLPPEQKAEREKERRVANNARERLRVRDINEAFKELGRMCQLHLNSEKPQTKLLILHQAVSVILNLEQQVRERNLNPKAACLKRREEEKVSGVVGDPQMVLSAPHPGLSEAHNPAGHM | B cell differentiation B cell lineage commitment immunoglobulin V(D)J recombination negative regulation of transcription by RNA polymerase II nervous system development positive regulation of B cell proliferation positive regulation of cell cycle positive regulation of DNA-binding transcription factor activity positive regulation of DNA-templated transcription positive regulation of neuron differentiation positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of G1/S transition of mitotic cell cycle regulation of transcription by RNA polymerase II chromatin; cytoplasm; euchromatin; nucleoplasm; nucleus; protein-containing complex; RNA polymerase II transcription regulator complex; transcription regulator complex bHLH transcription factor binding cis-regulatory region sequence-specific DNA binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor binding DNA-binding transcription repressor activity, RNA polymerase II-specific E-box binding mitogen-activated protein kinase kinase kinase binding protein heterodimerization activity protein homodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II-specific DNA-binding transcription factor binding vitamin D response element binding Homo sapiens 3D-structure Alternative splicing Chromosomal rearrangement Differentiation Disease variant DNA-binding Isopeptide bond Methylation Neurogenesis Nucleus Phosphoprotein Proto-oncogene Reference proteome Transcription Transcription regulation Ubl conjugation MNQPQRMAPV MNQPQRMAPVGTDKELSDLLDFSMMFPLPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSLSSSTFLGPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGRHAGLVGGSHPEDGLAGSTSLMHNHAALPSQPGTLPDLSRPPDSYSGLGRAGATAAASEIKREEKEDEENTSAADHSEEEKKELKAPRARTSPDEDEDDLLPPEQKAEREKERRVANNARERLRVRDINEAFKELGRMCQLHLNSEKPQTKLLILHQAVSVILNLEQQVRERNLNPKAACLKRREEEKVSGVVGDPQMVLSAPHPGLSEAHNPAGHM |
base-excision repair DNA replication double-strand break repair via homologous recombination mismatch repair mitotic G1 DNA damage checkpoint signaling nucleotide-excision repair protein localization to chromosome regulation of DNA damage checkpoint regulation of double-strand break repair via homologous recombination telomere maintenance | chromatin; chromosome, telomeric region; DNA replication factor A complex; nuclear body; nucleoplasm; nucleus; PML body | damaged DNA binding enzyme binding G-rich strand telomeric DNA binding protein phosphatase binding single-stranded DNA binding telomeric DNA binding ubiquitin protein ligase binding | Homo sapiens | 3D-structure Acetylation Alternative splicing Direct protein sequencing DNA damage DNA recombination DNA repair DNA replication DNA-binding Isopeptide bond Nucleus Phosphoprotein Reference proteome Ubl conjugation | MWNSGFESYG | MWNSGFESYGSSSYGGAGGYTQSPGGFGSPAPSQAEKKSRARAQHIVPCTISQLLSATLVDEVFRIGNVEISQVTIVGIIRHAEKAPTNIVYKIDDMTAAPMDVRQWVDTDDTSSENTVVPPETYVKVAGHLRSFQNKKSLVAFKIMPLEDMNEFTTHILEVINAHMVLSKANSQPSAGRAPISNPGMSEAGNFGGNSFMPANGLTVAQNQVLNLIKACPRPEGLNFQDLKNQLKHMSVSSIKQAVDFLSNEGHIYSTVDDDHFKSTDAE | base-excision repair DNA replication double-strand break repair via homologous recombination mismatch repair mitotic G1 DNA damage checkpoint signaling nucleotide-excision repair protein localization to chromosome regulation of DNA damage checkpoint regulation of double-strand break repair via homologous recombination telomere maintenance chromatin; chromosome, telomeric region; DNA replication factor A complex; nuclear body; nucleoplasm; nucleus; PML body damaged DNA binding enzyme binding G-rich strand telomeric DNA binding protein phosphatase binding single-stranded DNA binding telomeric DNA binding ubiquitin protein ligase binding Homo sapiens 3D-structure Acetylation Alternative splicing Direct protein sequencing DNA damage DNA recombination DNA repair DNA replication DNA-binding Isopeptide bond Nucleus Phosphoprotein Reference proteome Ubl conjugation MWNSGFESYG MWNSGFESYGSSSYGGAGGYTQSPGGFGSPAPSQAEKKSRARAQHIVPCTISQLLSATLVDEVFRIGNVEISQVTIVGIIRHAEKAPTNIVYKIDDMTAAPMDVRQWVDTDDTSSENTVVPPETYVKVAGHLRSFQNKKSLVAFKIMPLEDMNEFTTHILEVINAHMVLSKANSQPSAGRAPISNPGMSEAGNFGGNSFMPANGLTVAQNQVLNLIKACPRPEGLNFQDLKNQLKHMSVSSIKQAVDFLSNEGHIYSTVDDDHFKSTDAE |
axonogenesis central nervous system development cholesterol metabolic process extracellular matrix organization forebrain development intracellular copper ion homeostasis locomotory behavior mating behavior midbrain development neuromuscular process controlling balance suckling behavior | membrane; nucleus; spine apparatus | heparin binding identical protein binding serine-type endopeptidase inhibitor activity transition metal ion binding | Rattus norvegicus | Alternative splicing Copper Disulfide bond Glycoprotein Membrane Metal-binding Phosphoprotein Protease inhibitor Proteoglycan Reference proteome Serine protease inhibitor Signal Transmembrane Transmembrane helix | MAATGTAAAA | MAATGTAAAAATGKLLVLLLLGLTAPAAALAGYIEALAANAGTGFAVAEPQIAMFCGKLNMHVNIQTGKWEPDPTGTKSCLGTKEEVLQYCQEIYPELQITNVMEANQPVNIDSWCRRDKKQCRSHIVIPFKCLVGEFVSDVLLVPENCQFFHQERMEVCEKHQRWHTVVKEACLTEGMTLYSYGMLLPCGVDQFHGTEYVCCPQTKVVDSDSTMSKEEEEEEEEDEEEDYALDKSEFPTEADLEDFTEAAADEDEDEEEEEEEEGEEVVEDRDYYYDSFKGDDYNEENPTEPSSDGTISDKEIAHDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKTMIPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRSRMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRIALENYLAALQSDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTSSISENPVDVRVSSEESEEIPPFHPFHPFPSLSENEDTQPELYHPMKKGSGMAEQDGGLIGAEEKVINSKNKMDENMVIDETLDVKEMIFNAERVGGLEEEPDSVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLRKRQYGTISHGIVEVHPMLTPEERHLNKMQNHGYENPTYKYLEQMQI | axonogenesis central nervous system development cholesterol metabolic process extracellular matrix organization forebrain development intracellular copper ion homeostasis locomotory behavior mating behavior midbrain development neuromuscular process controlling balance suckling behavior membrane; nucleus; spine apparatus heparin binding identical protein binding serine-type endopeptidase inhibitor activity transition metal ion binding Rattus norvegicus Alternative splicing Copper Disulfide bond Glycoprotein Membrane Metal-binding Phosphoprotein Protease inhibitor Proteoglycan Reference proteome Serine protease inhibitor Signal Transmembrane Transmembrane helix MAATGTAAAA MAATGTAAAAATGKLLVLLLLGLTAPAAALAGYIEALAANAGTGFAVAEPQIAMFCGKLNMHVNIQTGKWEPDPTGTKSCLGTKEEVLQYCQEIYPELQITNVMEANQPVNIDSWCRRDKKQCRSHIVIPFKCLVGEFVSDVLLVPENCQFFHQERMEVCEKHQRWHTVVKEACLTEGMTLYSYGMLLPCGVDQFHGTEYVCCPQTKVVDSDSTMSKEEEEEEEEDEEEDYALDKSEFPTEADLEDFTEAAADEDEDEEEEEEEEGEEVVEDRDYYYDSFKGDDYNEENPTEPSSDGTISDKEIAHDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKTMIPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRSRMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRIALENYLAALQSDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTSSISENPVDVRVSSEESEEIPPFHPFHPFPSLSENEDTQPELYHPMKKGSGMAEQDGGLIGAEEKVINSKNKMDENMVIDETLDVKEMIFNAERVGGLEEEPDSVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLRKRQYGTISHGIVEVHPMLTPEERHLNKMQNHGYENPTYKYLEQMQI |
proteolysis regulation of systemic arterial blood pressure zymogen activation | acrosomal vesicle; apical part of cell; extracellular space; nucleus; protein-containing complex; secretory granule | endopeptidase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides serine-type endopeptidase activity serine-type peptidase activity | Mus musculus | Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Serine protease Signal Zymogen | MWFLILFLAL | MWFLILFLALSLGGIDAAPPVQSRIFGGFNCEKNSQPWQVAVYRFTKYQCGGVLLNANWVLTAAHCHNDKYQVWLGKNNFFEDEPSAQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLKKPADITDVVKPIDLPTEEPKLGSTCLASGWGSITPVIYEPADDLQCVNFKLLPNEDCVKAHIEKVTDVMLCAGDMDGGKDTCMGDSGGPLICDGVLHGITSWGPSPCGKPNVPGIYTKLIKFNSWIKDTIAKNA | proteolysis regulation of systemic arterial blood pressure zymogen activation acrosomal vesicle; apical part of cell; extracellular space; nucleus; protein-containing complex; secretory granule endopeptidase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides serine-type endopeptidase activity serine-type peptidase activity Mus musculus Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Serine protease Signal Zymogen MWFLILFLAL MWFLILFLALSLGGIDAAPPVQSRIFGGFNCEKNSQPWQVAVYRFTKYQCGGVLLNANWVLTAAHCHNDKYQVWLGKNNFFEDEPSAQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLKKPADITDVVKPIDLPTEEPKLGSTCLASGWGSITPVIYEPADDLQCVNFKLLPNEDCVKAHIEKVTDVMLCAGDMDGGKDTCMGDSGGPLICDGVLHGITSWGPSPCGKPNVPGIYTKLIKFNSWIKDTIAKNA |
regulation of systemic arterial blood pressure zymogen activation | acrosomal vesicle; apical part of cell; extracellular space; nucleus; protein-containing complex; secretory granule | endopeptidase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides serine-type endopeptidase activity serine-type peptidase activity | Mus musculus | Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Serine protease Signal Zymogen | MWFLILFLAL | MWFLILFLALSLGGIDAAPPVQSRIVGGFNCEKNSQPWHVAVYRYNKYICGGVLLDRNWVLTAAHCHVSQYNVWLGKTKLFQREPSAQHRMVSKSFPHPDYNMSLLIIHNPEPEDDESNDLMLLRLSEPADITDAVKPIALPTEEPKLGSTCLVSGWGSITPTKFQTPDDLQCVSIKLLPNEVCVKNHNQKVTDVMLCAGEMGGGKDTCKGDSGGPLICDGVLHGITAWGPIPCGKPNTPGVYTKLIKFTNWIKDTMAKNP | regulation of systemic arterial blood pressure zymogen activation acrosomal vesicle; apical part of cell; extracellular space; nucleus; protein-containing complex; secretory granule endopeptidase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides serine-type endopeptidase activity serine-type peptidase activity Mus musculus Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Serine protease Signal Zymogen MWFLILFLAL MWFLILFLALSLGGIDAAPPVQSRIVGGFNCEKNSQPWHVAVYRYNKYICGGVLLDRNWVLTAAHCHVSQYNVWLGKTKLFQREPSAQHRMVSKSFPHPDYNMSLLIIHNPEPEDDESNDLMLLRLSEPADITDAVKPIALPTEEPKLGSTCLVSGWGSITPTKFQTPDDLQCVSIKLLPNEVCVKNHNQKVTDVMLCAGEMGGGKDTCKGDSGGPLICDGVLHGITAWGPIPCGKPNTPGVYTKLIKFTNWIKDTMAKNP |
regulation of systemic arterial blood pressure zymogen activation | acrosomal vesicle; apical part of cell; extracellular space; nucleus; protein-containing complex; secretory granule | endopeptidase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides serine-type endopeptidase activity serine-type peptidase activity | Mus musculus | Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Serine protease Signal Zymogen | MRFLILFLAL | MRFLILFLALSLGGIDAAPPVQSRIVGGFNCEKNSQPWQVAVYRFTKYQCGGILLNANWVLTAAHCHNDKYQVWLGKNNFLEDEPSAQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLKKPADITDVVKPIDLPTEEPKLGSTCLASGWGSITPVKYEYPDELQCVNLKLLPNEDCAKAHIEKVTDDMLCAGDMDGGKDTCAGDSGGPLICDGVLQGITSWGPSPCGKPNVPGIYTRVLNFNTWIRETMAEND | regulation of systemic arterial blood pressure zymogen activation acrosomal vesicle; apical part of cell; extracellular space; nucleus; protein-containing complex; secretory granule endopeptidase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides serine-type endopeptidase activity serine-type peptidase activity Mus musculus Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Serine protease Signal Zymogen MRFLILFLAL MRFLILFLALSLGGIDAAPPVQSRIVGGFNCEKNSQPWQVAVYRFTKYQCGGILLNANWVLTAAHCHNDKYQVWLGKNNFLEDEPSAQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLKKPADITDVVKPIDLPTEEPKLGSTCLASGWGSITPVKYEYPDELQCVNLKLLPNEDCAKAHIEKVTDDMLCAGDMDGGKDTCAGDSGGPLICDGVLQGITSWGPSPCGKPNVPGIYTRVLNFNTWIRETMAEND |
regulation of systemic arterial blood pressure zymogen activation | acrosomal vesicle; apical part of cell; extracellular space; nucleus; protein-containing complex; secretory granule | endopeptidase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides peptidase activity serine-type endopeptidase activity serine-type peptidase activity | Mus musculus | Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Serine protease Signal Zymogen | MRFLILFLTL | MRFLILFLTLSLGGIDAAPPVQSRILGGFKCEKNSQPWQVAVYYLDEYLCGGVLLDRNWVLTAAHCYEDKYNIWLGKNKLFQDEPSAQHRLVSKSFPHPDFNMSLLQSVPTGADLSNDLMLLRLSKPADITDVVKPIDLPTTEPKLGSTCLASGWGSINQLIYQNPNDLQCVSIKLHPNEVCVKAHILKVTDVMLCAGEMNGGKDTCKGDSGGPLICDGVLQGITSWGSTPCGEPNAPAIYTKLIKFTSWIKDTMAKNP | regulation of systemic arterial blood pressure zymogen activation acrosomal vesicle; apical part of cell; extracellular space; nucleus; protein-containing complex; secretory granule endopeptidase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides peptidase activity serine-type endopeptidase activity serine-type peptidase activity Mus musculus Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Serine protease Signal Zymogen MRFLILFLTL MRFLILFLTLSLGGIDAAPPVQSRILGGFKCEKNSQPWQVAVYYLDEYLCGGVLLDRNWVLTAAHCYEDKYNIWLGKNKLFQDEPSAQHRLVSKSFPHPDFNMSLLQSVPTGADLSNDLMLLRLSKPADITDVVKPIDLPTTEPKLGSTCLASGWGSINQLIYQNPNDLQCVSIKLHPNEVCVKAHILKVTDVMLCAGEMNGGKDTCKGDSGGPLICDGVLQGITSWGSTPCGEPNAPAIYTKLIKFTSWIKDTMAKNP |
regulation of systemic arterial blood pressure zymogen activation | acrosomal vesicle; apical part of cell; extracellular space; nucleus; protein-containing complex; secretory granule | endopeptidase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides peptidase activity serine-type endopeptidase activity serine-type peptidase activity | Mus musculus | Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Serine protease Signal Zymogen | MRFLILFLAL | MRFLILFLALSLGGIDAAPPVHSRIVGGFKCEKNSQPWHVAVYRYNEYICGGVLLDANWVLTAAHCYYEENKVSLGKNNLYEEEPSAQHRLVSKSFLHPGYNRSLHRNHIRHPEYDYSNDLMLLRLSKPADITDVVKPIALPTEEPKLGSTCLASGWGSTTPFKFQNAKDLQCVNLKLLPNEDCGKAHIEKVTDVMLCAGETDGGKDTCKGDSGGPLICDGVLQGITSWGFTPCGEPKKPGVYTKLIKFTSWIKDTMAKNL | regulation of systemic arterial blood pressure zymogen activation acrosomal vesicle; apical part of cell; extracellular space; nucleus; protein-containing complex; secretory granule endopeptidase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides peptidase activity serine-type endopeptidase activity serine-type peptidase activity Mus musculus Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Serine protease Signal Zymogen MRFLILFLAL MRFLILFLALSLGGIDAAPPVHSRIVGGFKCEKNSQPWHVAVYRYNEYICGGVLLDANWVLTAAHCYYEENKVSLGKNNLYEEEPSAQHRLVSKSFLHPGYNRSLHRNHIRHPEYDYSNDLMLLRLSKPADITDVVKPIALPTEEPKLGSTCLASGWGSTTPFKFQNAKDLQCVNLKLLPNEDCGKAHIEKVTDVMLCAGETDGGKDTCKGDSGGPLICDGVLQGITSWGFTPCGEPKKPGVYTKLIKFTSWIKDTMAKNL |
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity | external side of plasma membrane; extracellular space; lumenal side of endoplasmic reticulum membrane; MHC class I protein complex; phagocytic vesicle membrane | peptide antigen binding signaling receptor binding | Rattus norvegicus | Direct protein sequencing Disulfide bond Glycoprotein Immunity Membrane MHC I Reference proteome Signal Transmembrane Transmembrane helix | MGAMAPRTLL | MGAMAPRTLLLLLAAVLAPTQTWAGSHSLRYFHTAVSRPGLGEPRFISVGYVDDTQFVRYDSDAENPRYEPRARWMEREGPEYWEEQTLVAKGQELDYRVSLRNLLSYYNQSEGGSHTIQRMYGCDVGSDGSLLRGYEQHAYDGRDYIALNEDLKTWAVADFAAWITRSKWQRNGAAERSRAYLEGTCVEWLLRYLERGKETLLRSDPPEAHVTLHPRPEGDVTLRCWALGFYPADITLTWQLNGEDLTQDMELVETRPAGDGTFQKWASVVVPLGKEQNYTCRVEHEGLPEPLSQRWEPSPSTDSNLLLLFLELWQFL | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity external side of plasma membrane; extracellular space; lumenal side of endoplasmic reticulum membrane; MHC class I protein complex; phagocytic vesicle membrane peptide antigen binding signaling receptor binding Rattus norvegicus Direct protein sequencing Disulfide bond Glycoprotein Immunity Membrane MHC I Reference proteome Signal Transmembrane Transmembrane helix MGAMAPRTLL MGAMAPRTLLLLLAAVLAPTQTWAGSHSLRYFHTAVSRPGLGEPRFISVGYVDDTQFVRYDSDAENPRYEPRARWMEREGPEYWEEQTLVAKGQELDYRVSLRNLLSYYNQSEGGSHTIQRMYGCDVGSDGSLLRGYEQHAYDGRDYIALNEDLKTWAVADFAAWITRSKWQRNGAAERSRAYLEGTCVEWLLRYLERGKETLLRSDPPEAHVTLHPRPEGDVTLRCWALGFYPADITLTWQLNGEDLTQDMELVETRPAGDGTFQKWASVVVPLGKEQNYTCRVEHEGLPEPLSQRWEPSPSTDSNLLLLFLELWQFL |
cellular response to heat protein folding | cytoplasm; cytoplasmic stress granule; mitochondrion; nucleus | identical protein binding mRNA binding unfolded protein binding | Saccharomyces cerevisiae | 3D-structure Acetylation Phosphoprotein Reference proteome Stress response | MSFNSPFFDF | MSFNSPFFDFFDNINNEVDAFNRLLGEGGLRGYAPRRQLANTPAKDSTGKEVARPNNYAGALYDPRDETLDDWFDNDLSLFPSGFGFPRSVAVPVDILDHDNNYELKVVVPGVKSKKDIDIEYHQNKNQILVSGEIPSTLNEESKDKVKVKESSSGKFKRVITLPDYPGVDADNIKADYANGVLTLTVPKLKPQKDGKNHVKKIEVSSQESWGN | cellular response to heat protein folding cytoplasm; cytoplasmic stress granule; mitochondrion; nucleus identical protein binding mRNA binding unfolded protein binding Saccharomyces cerevisiae 3D-structure Acetylation Phosphoprotein Reference proteome Stress response MSFNSPFFDF MSFNSPFFDFFDNINNEVDAFNRLLGEGGLRGYAPRRQLANTPAKDSTGKEVARPNNYAGALYDPRDETLDDWFDNDLSLFPSGFGFPRSVAVPVDILDHDNNYELKVVVPGVKSKKDIDIEYHQNKNQILVSGEIPSTLNEESKDKVKVKESSSGKFKRVITLPDYPGVDADNIKADYANGVLTLTVPKLKPQKDGKNHVKKIEVSSQESWGN |
phenylalanine transport tryptophan transport tyrosine transport | plasma membrane | L-phenylalanine transmembrane transporter activity L-tryptophan transmembrane transporter activity L-tyrosine transmembrane transporter activity | Escherichia coli | Amino-acid transport Cell inner membrane Cell membrane Membrane Reference proteome Transmembrane Transmembrane helix Transport | MMEGQQHGEQ | MMEGQQHGEQLKRGLKNRHIQLIALGGAIGTGLFLGSASVIQSAGPGIILGYAIAGFIAFLIMRQLGEMVVEEPVAGSFSHFAYKYWGSFAGFASGWNYWVLYVLVAMAELTAVGKYIQFWYPEIPTWVSAAVFFVVINAINLTNVKVFGEMEFWFAIIKVIAVVAMIIFGGWLLFSGNGGPQATVSNLWDQGGFLPHGFTGLVMMMAIIMFSFGGLELVGITAAEADNPEQSIPKATNQVIYRILIFYIGSLAVLLSLMPWTRVTADTSPFVLIFHELGDTFVANALNIVVLTAALSVYNSCVYCNSRMLFGLAQQGNAPKALASVDKRGVPVNTILVSALVTALCVLINYLAPESAFGLLMALVVSALVINWAMISLAHMKFRRAKQEQGVVTRFPALLYPLGNWICLLFMAAVLVIMLMTPGMAISVYLIPVWLIVLGIGYLFKEKTAKAVKAH | phenylalanine transport tryptophan transport tyrosine transport plasma membrane L-phenylalanine transmembrane transporter activity L-tryptophan transmembrane transporter activity L-tyrosine transmembrane transporter activity Escherichia coli Amino-acid transport Cell inner membrane Cell membrane Membrane Reference proteome Transmembrane Transmembrane helix Transport MMEGQQHGEQ MMEGQQHGEQLKRGLKNRHIQLIALGGAIGTGLFLGSASVIQSAGPGIILGYAIAGFIAFLIMRQLGEMVVEEPVAGSFSHFAYKYWGSFAGFASGWNYWVLYVLVAMAELTAVGKYIQFWYPEIPTWVSAAVFFVVINAINLTNVKVFGEMEFWFAIIKVIAVVAMIIFGGWLLFSGNGGPQATVSNLWDQGGFLPHGFTGLVMMMAIIMFSFGGLELVGITAAEADNPEQSIPKATNQVIYRILIFYIGSLAVLLSLMPWTRVTADTSPFVLIFHELGDTFVANALNIVVLTAALSVYNSCVYCNSRMLFGLAQQGNAPKALASVDKRGVPVNTILVSALVTALCVLINYLAPESAFGLLMALVVSALVINWAMISLAHMKFRRAKQEQGVVTRFPALLYPLGNWICLLFMAAVLVIMLMTPGMAISVYLIPVWLIVLGIGYLFKEKTAKAVKAH |
ATP biosynthetic process cellular response to dexamethasone stimulus cellular response to nitric oxide lipid metabolic process negative regulation of endothelial cell proliferation positive regulation of blood vessel endothelial cell migration proton motive force-driven ATP synthesis proton motive force-driven mitochondrial ATP synthesis response to ethanol response to muscle activity | cell surface; COP9 signalosome; membrane; membrane raft; mitochondrial inner membrane; mitochondrial proton-transporting ATP synthase complex; mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1); mitochondrial proton-transporting ATP synthase, catalytic core; mitochondrion; plasma membrane; proton-transporting ATP synthase complex; proton-transporting ATP synthase complex, catalytic core F(1) | ADP binding angiostatin binding ATP binding MHC class I protein binding protease binding proton-transporting ATP synthase activity, rotational mechanism | Rattus norvegicus | 3D-structure Acetylation ATP synthesis ATP-binding Cell membrane CF(1) Direct protein sequencing Glycoprotein Hydrogen ion transport Ion transport Membrane Methylation Mitochondrion Mitochondrion inner membrane Nucleotide-binding Phosphoprotein Reference proteome Transit peptide Transport | MLSVRIAAAV | MLSVRIAAAVARALPRRAGLVSKNALGSSFVGTRNLHASNTRLQKTGTAEMSSILEERILGADTSVDLEETGRVLSIGDGIARVHGLRNVQAEEMVEFSSGLKGMSLNLEPDNVGVVVFGNDKLIKEGDIVKRTGAIVDVPVGDELLGRVVDALGNAIDGKGPVGSKIRRRVGLKAPGIIPRISVREPMQTGIKAVDSLVPIGRGQRELIIGDRQTGKTSIAIDTIINQKRFNDGTDEKKKLYCIYVAIGQKRSTVAQLVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCSMGEYFRDNGKHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDSFGGGSLTALPVIETQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTRAMKQVAGTMKLELAQYREVAAFAQFGSDLDAATQQLLSRGVRLTELLKQGQYSPMAIEEQVAVIYAGVRGYLDKLEPSKITKFESAFLSHVVSQHQSLLGNIRSDGKISEQSDAKLKEIVTNFLAGFEP | ATP biosynthetic process cellular response to dexamethasone stimulus cellular response to nitric oxide lipid metabolic process negative regulation of endothelial cell proliferation positive regulation of blood vessel endothelial cell migration proton motive force-driven ATP synthesis proton motive force-driven mitochondrial ATP synthesis response to ethanol response to muscle activity cell surface; COP9 signalosome; membrane; membrane raft; mitochondrial inner membrane; mitochondrial proton-transporting ATP synthase complex; mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1); mitochondrial proton-transporting ATP synthase, catalytic core; mitochondrion; plasma membrane; proton-transporting ATP synthase complex; proton-transporting ATP synthase complex, catalytic core F(1) ADP binding angiostatin binding ATP binding MHC class I protein binding protease binding proton-transporting ATP synthase activity, rotational mechanism Rattus norvegicus 3D-structure Acetylation ATP synthesis ATP-binding Cell membrane CF(1) Direct protein sequencing Glycoprotein Hydrogen ion transport Ion transport Membrane Methylation Mitochondrion Mitochondrion inner membrane Nucleotide-binding Phosphoprotein Reference proteome Transit peptide Transport MLSVRIAAAV MLSVRIAAAVARALPRRAGLVSKNALGSSFVGTRNLHASNTRLQKTGTAEMSSILEERILGADTSVDLEETGRVLSIGDGIARVHGLRNVQAEEMVEFSSGLKGMSLNLEPDNVGVVVFGNDKLIKEGDIVKRTGAIVDVPVGDELLGRVVDALGNAIDGKGPVGSKIRRRVGLKAPGIIPRISVREPMQTGIKAVDSLVPIGRGQRELIIGDRQTGKTSIAIDTIINQKRFNDGTDEKKKLYCIYVAIGQKRSTVAQLVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCSMGEYFRDNGKHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDSFGGGSLTALPVIETQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTRAMKQVAGTMKLELAQYREVAAFAQFGSDLDAATQQLLSRGVRLTELLKQGQYSPMAIEEQVAVIYAGVRGYLDKLEPSKITKFESAFLSHVVSQHQSLLGNIRSDGKISEQSDAKLKEIVTNFLAGFEP |
adaptive immune response calcium-mediated signaling cell adhesion cellular response to granulocyte macrophage colony-stimulating factor stimulus defense response to Gram-negative bacterium helper T cell enhancement of adaptive immune response interleukin-15-mediated signaling pathway macrophage differentiation maintenance of protein location in cell positive regulation of calcium-mediated signaling positive regulation of canonical NF-kappaB signal transduction positive regulation of DNA-templated transcription positive regulation of ERK1 and ERK2 cascade positive regulation of monocyte differentiation positive regulation of peptidyl-tyrosine phosphorylation positive regulation of T cell activation positive regulation of viral entry into host cell regulation of calcium ion transport T cell activation T cell differentiation T cell selection | endoplasmic reticulum lumen; endoplasmic reticulum membrane; external side of plasma membrane; membrane raft | coreceptor activity interleukin-16 binding interleukin-16 receptor activity MHC class II protein binding MHC class II protein complex binding protein homodimerization activity protein tyrosine kinase binding zinc ion binding | Pan troglodytes | Adaptive immunity Cell membrane Disulfide bond Glycoprotein Immunity Immunoglobulin domain Lipoprotein Membrane Palmitate Phosphoprotein Reference proteome Repeat Signal Transmembrane Transmembrane helix | MNRGVPFRHL | MNRGVPFRHLLLVLQLALLPAATQGKKVVLGKKGDTVELTCTASQKKSIQFHWKNSNQTKILGNQGSFLTKGPSKLNDRVDSRRSLWDQGNFTLIIKNLKIEDSDTYICEVGDQKEEVQLLVFGLTANSDTHLLQGQSLTLTLESPPGSSPSVQCRSPRGKNIQGGKTLSVSQLELQDSGTWTCTVLQNQKKVEFKIDIVVLAFQKASSIVYKKEGEQVEFSFPLAFTVEKLTGSGELWWQAERASSSKSWITFDLKNKEVSVKRVTQDPKLQMGKKLPLHLTLPQALPQYAGSGNLTLALEAKTGKLHQEVNLVVMRATQLQKNLTCEVWGPTSPKLMLSLKLENKEAKVSKREKAVWVLNPEAGMWQCLLSDSGQVLLESNIKVLPTWSTPVQPMALIVLGGVAGLLLFIGLGIFFCVRCRHRRRQAQRMSQIKRLLSEKKTCQCPHRFQKTCSPI | adaptive immune response calcium-mediated signaling cell adhesion cellular response to granulocyte macrophage colony-stimulating factor stimulus defense response to Gram-negative bacterium helper T cell enhancement of adaptive immune response interleukin-15-mediated signaling pathway macrophage differentiation maintenance of protein location in cell positive regulation of calcium-mediated signaling positive regulation of canonical NF-kappaB signal transduction positive regulation of DNA-templated transcription positive regulation of ERK1 and ERK2 cascade positive regulation of monocyte differentiation positive regulation of peptidyl-tyrosine phosphorylation positive regulation of T cell activation positive regulation of viral entry into host cell regulation of calcium ion transport T cell activation T cell differentiation T cell selection endoplasmic reticulum lumen; endoplasmic reticulum membrane; external side of plasma membrane; membrane raft coreceptor activity interleukin-16 binding interleukin-16 receptor activity MHC class II protein binding MHC class II protein complex binding protein homodimerization activity protein tyrosine kinase binding zinc ion binding Pan troglodytes Adaptive immunity Cell membrane Disulfide bond Glycoprotein Immunity Immunoglobulin domain Lipoprotein Membrane Palmitate Phosphoprotein Reference proteome Repeat Signal Transmembrane Transmembrane helix MNRGVPFRHL MNRGVPFRHLLLVLQLALLPAATQGKKVVLGKKGDTVELTCTASQKKSIQFHWKNSNQTKILGNQGSFLTKGPSKLNDRVDSRRSLWDQGNFTLIIKNLKIEDSDTYICEVGDQKEEVQLLVFGLTANSDTHLLQGQSLTLTLESPPGSSPSVQCRSPRGKNIQGGKTLSVSQLELQDSGTWTCTVLQNQKKVEFKIDIVVLAFQKASSIVYKKEGEQVEFSFPLAFTVEKLTGSGELWWQAERASSSKSWITFDLKNKEVSVKRVTQDPKLQMGKKLPLHLTLPQALPQYAGSGNLTLALEAKTGKLHQEVNLVVMRATQLQKNLTCEVWGPTSPKLMLSLKLENKEAKVSKREKAVWVLNPEAGMWQCLLSDSGQVLLESNIKVLPTWSTPVQPMALIVLGGVAGLLLFIGLGIFFCVRCRHRRRQAQRMSQIKRLLSEKKTCQCPHRFQKTCSPI |
cell wall macromolecule catabolic process defense response to bacterium disruption by virus of host cell wall peptidoglycan during virus entry disruption of host cell envelope during viral entry entry into host killing of cells of another organism peptidoglycan catabolic process viral entry into host cell viral tail assembly | virus tail; virus tail, baseplate | identical protein binding lysozyme activity | Enterobacteria phage T4 | 3D-structure Antimicrobial Bacteriolytic enzyme Degradation of host cell envelope components during virus entry Degradation of host peptidoglycans during virus entry Direct protein sequencing Glycosidase Hydrolase Late protein Reference proteome Viral baseplate protein Viral genome ejection through host cell envelope Viral penetration into host cytoplasm Viral release from host cell Viral tail assembly Viral tail protein Virion Virus entry into host cell | MEMISNNLNW | MEMISNNLNWFVGVVEDRMDPLKLGRVRVRVVGLHPPQRAQGDVMGIPTEKLPWMSVIQPITSAAMSGIGGSVTGPVEGTRVYGHFLDKWKTNGIVLGTYGGIVREKPNRLEGFSDPTGQYPRRLGNDTNVLNQGGEVGYDSSSNVIQDSNLDTAINPDDRPLSEIPTDDNPNMSMAEMLRRDEGLRLKVYWDTEGYPTIGIGHLIMKQPVRDMAQINKVLSKQVGREITGNPGSITMEEATTLFERDLADMQRDIKSHSKVGPVWQAVNRSRQMALENMAFQMGVGGVAKFNTMLTAMLAGDWEKAYKAGRDSLWYQQTKGRASRVTMIILTGNLESYGVEVKTPARSLSAMAATVAKSSDPADPPIPNDSRILFKEPVSSYKGEYPYVHTMETESGHIQEFDDTPGQERYRLVHPTGTYEEVSPSGRRTRKTVDNLYDITNADGNFLVAGDKKTNVGGSEIYYNMDNRLHQIDGSNTIFVRGDETKTVEGNGTILVKGNVTIIVEGNADITVKGDATTLVEGNQTNTVNGNLSWKVAGTVDWDVGGDWTEKMASMSSISSGQYTIDGSRIDIG | cell wall macromolecule catabolic process defense response to bacterium disruption by virus of host cell wall peptidoglycan during virus entry disruption of host cell envelope during viral entry entry into host killing of cells of another organism peptidoglycan catabolic process viral entry into host cell viral tail assembly virus tail; virus tail, baseplate identical protein binding lysozyme activity Enterobacteria phage T4 3D-structure Antimicrobial Bacteriolytic enzyme Degradation of host cell envelope components during virus entry Degradation of host peptidoglycans during virus entry Direct protein sequencing Glycosidase Hydrolase Late protein Reference proteome Viral baseplate protein Viral genome ejection through host cell envelope Viral penetration into host cytoplasm Viral release from host cell Viral tail assembly Viral tail protein Virion Virus entry into host cell MEMISNNLNW MEMISNNLNWFVGVVEDRMDPLKLGRVRVRVVGLHPPQRAQGDVMGIPTEKLPWMSVIQPITSAAMSGIGGSVTGPVEGTRVYGHFLDKWKTNGIVLGTYGGIVREKPNRLEGFSDPTGQYPRRLGNDTNVLNQGGEVGYDSSSNVIQDSNLDTAINPDDRPLSEIPTDDNPNMSMAEMLRRDEGLRLKVYWDTEGYPTIGIGHLIMKQPVRDMAQINKVLSKQVGREITGNPGSITMEEATTLFERDLADMQRDIKSHSKVGPVWQAVNRSRQMALENMAFQMGVGGVAKFNTMLTAMLAGDWEKAYKAGRDSLWYQQTKGRASRVTMIILTGNLESYGVEVKTPARSLSAMAATVAKSSDPADPPIPNDSRILFKEPVSSYKGEYPYVHTMETESGHIQEFDDTPGQERYRLVHPTGTYEEVSPSGRRTRKTVDNLYDITNADGNFLVAGDKKTNVGGSEIYYNMDNRLHQIDGSNTIFVRGDETKTVEGNGTILVKGNVTIIVEGNADITVKGDATTLVEGNQTNTVNGNLSWKVAGTVDWDVGGDWTEKMASMSSISSGQYTIDGSRIDIG |
one-carbon metabolic process response to bacterium response to oxidative stress | cytoplasm; cytosol | carbonate dehydratase activity nickel cation binding phosphatase activity zinc ion binding | Mus musculus | Acetylation Cytoplasm Direct protein sequencing Glutathionylation Lyase Metal-binding Phosphoprotein Reference proteome Zinc | MAKEWGYASH | MAKEWGYASHNGPDHWHELYPIAKGDNQSPIELHTKDIKHDPSLQPWSASYDPGSAKTILNNGKTCRVVFDDTYDRSMLRGGPLSGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWNPKYNTFGEALKQPDGIAVVGIFLKIGREKGEFQILLDALDKIKTKGKEAPFTHFDPSCLFPACRDYWTYHGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLFSSAENEPPVPLVGNWRPPQPVKGRVVRASFK | one-carbon metabolic process response to bacterium response to oxidative stress cytoplasm; cytosol carbonate dehydratase activity nickel cation binding phosphatase activity zinc ion binding Mus musculus Acetylation Cytoplasm Direct protein sequencing Glutathionylation Lyase Metal-binding Phosphoprotein Reference proteome Zinc MAKEWGYASH MAKEWGYASHNGPDHWHELYPIAKGDNQSPIELHTKDIKHDPSLQPWSASYDPGSAKTILNNGKTCRVVFDDTYDRSMLRGGPLSGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWNPKYNTFGEALKQPDGIAVVGIFLKIGREKGEFQILLDALDKIKTKGKEAPFTHFDPSCLFPACRDYWTYHGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLFSSAENEPPVPLVGNWRPPQPVKGRVVRASFK |
methanol metabolic process | outer membrane-bounded periplasmic space; plasma membrane | alcohol dehydrogenase (cytochrome c(L)) activity calcium ion binding | Methylorubrum extorquens | 3D-structure Calcium Cell inner membrane Cell membrane Direct protein sequencing Disulfide bond Membrane Metal-binding Methanol utilization Oxidoreductase PQQ Reference proteome Signal | MSRFVTSVSA | MSRFVTSVSALAMLALAPAALSSGAYANDKLVELSKSDDNWVMPGKNYDSNNFSDLKQINKGNVKQLRPAWTFSTGLLNGHEGAPLVVDGKMYIHTSFPNNTFALGLDDPGTILWQDKPKQNPAARAVACCDLVNRGLAYWPGDGKTPALILKTQLDGNVAALNAETGETVWKVENSDIKVGSTLTIAPYVVKDKVIIGSSGAELGVRGYLTAYDVKTGEQVWRAYATGPDKDLLLASDFNIKNPHYGQKGLGTGTWEGDAWKIGGGTNWGWYAYDPGTNLIYFGTGNPAPWNETMRPGDNKWTMTIFGRDADTGEAKFGYQKTPHDEWDYAGVNVMMLSEQKDKDGKARKLLTHPDRNGIVYTLDRTDGALVSANKLDDTVNVFKSVDLKTGQPVRDPEYGTRMDHLAKDICPSAMGYHNQGHDSYDPKRELFFMGINHICMDWEPFMLPYRAGQFFVGATLNMYPGPKGDRQNYEGLGQIKAYNAITGDYKWEKMERFAVWGGTMATAGDLVFYGTLDGYLKARDSDTGDLLWKFKIPSGAIGYPMTYTHKGTQYVAIYYGVGGWPGVGLVFDLADPTAGLGAVGAFKKLANYTQMGGGVVVFSLDGKGPYDDPNVGEWKSAAK | methanol metabolic process outer membrane-bounded periplasmic space; plasma membrane alcohol dehydrogenase (cytochrome c(L)) activity calcium ion binding Methylorubrum extorquens 3D-structure Calcium Cell inner membrane Cell membrane Direct protein sequencing Disulfide bond Membrane Metal-binding Methanol utilization Oxidoreductase PQQ Reference proteome Signal MSRFVTSVSA MSRFVTSVSALAMLALAPAALSSGAYANDKLVELSKSDDNWVMPGKNYDSNNFSDLKQINKGNVKQLRPAWTFSTGLLNGHEGAPLVVDGKMYIHTSFPNNTFALGLDDPGTILWQDKPKQNPAARAVACCDLVNRGLAYWPGDGKTPALILKTQLDGNVAALNAETGETVWKVENSDIKVGSTLTIAPYVVKDKVIIGSSGAELGVRGYLTAYDVKTGEQVWRAYATGPDKDLLLASDFNIKNPHYGQKGLGTGTWEGDAWKIGGGTNWGWYAYDPGTNLIYFGTGNPAPWNETMRPGDNKWTMTIFGRDADTGEAKFGYQKTPHDEWDYAGVNVMMLSEQKDKDGKARKLLTHPDRNGIVYTLDRTDGALVSANKLDDTVNVFKSVDLKTGQPVRDPEYGTRMDHLAKDICPSAMGYHNQGHDSYDPKRELFFMGINHICMDWEPFMLPYRAGQFFVGATLNMYPGPKGDRQNYEGLGQIKAYNAITGDYKWEKMERFAVWGGTMATAGDLVFYGTLDGYLKARDSDTGDLLWKFKIPSGAIGYPMTYTHKGTQYVAIYYGVGGWPGVGLVFDLADPTAGLGAVGAFKKLANYTQMGGGVVVFSLDGKGPYDDPNVGEWKSAAK |
photosynthetic electron transport in photosystem II response to herbicide | plasma membrane-derived thylakoid membrane; plasma membrane-derived thylakoid photosystem II | chlorophyll binding electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity iron ion binding oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor oxygen evolving activity | Synechocystis sp. | 3D-structure Calcium Chlorophyll Chromophore Electron transport Herbicide resistance Iron Magnesium Manganese Membrane Metal-binding Oxidoreductase Photosynthesis Photosystem II Reference proteome Thylakoid Transmembrane Transmembrane helix Transport | MTTTLQQRES | MTTTLQQRESASLWEQFCQWVTSTNNRIYVGWFGTLMIPTLLTATTCFIIAFIAAPPVDIDGIREPVAGSLLYGNNIISGAVVPSSNAIGLHFYPIWEAASLDEWLYNGGPYQLVVFHFLIGIFCYMGRQWELSYRLGMRPWICVAYSAPVSAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLVRETTEVESQNYGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLGAWPVIGIWFTAMGVSTMAFNLNGFNFNQSILDSQGRVIGTWADVLNRANIGFEVMHERNAHNFPLDLASGEQAPVALTAPAVNG | photosynthetic electron transport in photosystem II response to herbicide plasma membrane-derived thylakoid membrane; plasma membrane-derived thylakoid photosystem II chlorophyll binding electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity iron ion binding oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor oxygen evolving activity Synechocystis sp. 3D-structure Calcium Chlorophyll Chromophore Electron transport Herbicide resistance Iron Magnesium Manganese Membrane Metal-binding Oxidoreductase Photosynthesis Photosystem II Reference proteome Thylakoid Transmembrane Transmembrane helix Transport MTTTLQQRES MTTTLQQRESASLWEQFCQWVTSTNNRIYVGWFGTLMIPTLLTATTCFIIAFIAAPPVDIDGIREPVAGSLLYGNNIISGAVVPSSNAIGLHFYPIWEAASLDEWLYNGGPYQLVVFHFLIGIFCYMGRQWELSYRLGMRPWICVAYSAPVSAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLVRETTEVESQNYGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLGAWPVIGIWFTAMGVSTMAFNLNGFNFNQSILDSQGRVIGTWADVLNRANIGFEVMHERNAHNFPLDLASGEQAPVALTAPAVNG |
negative regulation of membrane protein ectodomain proteolysis negative regulation of metallopeptidase activity response to cytokine response to hormone | collagen-containing extracellular matrix; extracellular matrix; extracellular region; extracellular space; ficolin-1-rich granule lumen; specific granule lumen; tertiary granule lumen | metalloendopeptidase inhibitor activity molecular function inhibitor activity peptidase inhibitor activity protease binding zinc ion binding | Homo sapiens | 3D-structure Direct protein sequencing Disulfide bond Metal-binding Metalloenzyme inhibitor Metalloprotease inhibitor Protease inhibitor Reference proteome Secreted Signal Zinc | MGAAARTLRL | MGAAARTLRLALGLLLLATLLRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPEKDIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITLCDFIVPWDTLSTTQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKNINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP | negative regulation of membrane protein ectodomain proteolysis negative regulation of metallopeptidase activity response to cytokine response to hormone collagen-containing extracellular matrix; extracellular matrix; extracellular region; extracellular space; ficolin-1-rich granule lumen; specific granule lumen; tertiary granule lumen metalloendopeptidase inhibitor activity molecular function inhibitor activity peptidase inhibitor activity protease binding zinc ion binding Homo sapiens 3D-structure Direct protein sequencing Disulfide bond Metal-binding Metalloenzyme inhibitor Metalloprotease inhibitor Protease inhibitor Reference proteome Secreted Signal Zinc MGAAARTLRL MGAAARTLRLALGLLLLATLLRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPEKDIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITLCDFIVPWDTLSTTQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKNINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP |
cellular senescence centrosome cycle chromatin remodeling DNA repair negative regulation of cell population proliferation positive regulation of transcription by RNA polymerase II regulation of centrosome duplication regulation of endodeoxyribonuclease activity regulation of endoribonuclease activity ribosomal large subunit biogenesis ribosomal large subunit export from nucleus ribosomal small subunit biogenesis ribosomal small subunit export from nucleus rRNA export from nucleus | centrosome; cytoplasm; nucleolus; nucleoplasm; nucleus; ribonucleoprotein complex | chromatin binding histone binding NF-kappaB binding RNA binding unfolded protein binding | Gallus gallus | Chaperone Cytoplasm Nucleus Phosphoprotein Reference proteome RNA-binding | MEDSAMDMES | MEDSAMDMESMGPLRPQTFLFGCELKAEKEYQFKVDDEENEHQLSLRTVTLGAGAKDELHVVEAEALDYEGNPTKVVLASLKMSVQPTVSLGGFEITPPFVLRLKCGSGPVYVSGQHLVALEEEPESEDEEEDTKIGNASTKRPASGGGAKTPQKKPKLSEDDEDDDEDEDDDEDDEDDLDDDEEEIKTPMKKPAREPAGKNMQKAKQNGKDSKPSTPASKTKTPDSKKDKSLTPKTPKVPLSLEEIKAKMQASVDKGCSLPKLEPKFANYVKNCFRTEDQKVIQALWQWRQTL | cellular senescence centrosome cycle chromatin remodeling DNA repair negative regulation of cell population proliferation positive regulation of transcription by RNA polymerase II regulation of centrosome duplication regulation of endodeoxyribonuclease activity regulation of endoribonuclease activity ribosomal large subunit biogenesis ribosomal large subunit export from nucleus ribosomal small subunit biogenesis ribosomal small subunit export from nucleus rRNA export from nucleus centrosome; cytoplasm; nucleolus; nucleoplasm; nucleus; ribonucleoprotein complex chromatin binding histone binding NF-kappaB binding RNA binding unfolded protein binding Gallus gallus Chaperone Cytoplasm Nucleus Phosphoprotein Reference proteome RNA-binding MEDSAMDMES MEDSAMDMESMGPLRPQTFLFGCELKAEKEYQFKVDDEENEHQLSLRTVTLGAGAKDELHVVEAEALDYEGNPTKVVLASLKMSVQPTVSLGGFEITPPFVLRLKCGSGPVYVSGQHLVALEEEPESEDEEEDTKIGNASTKRPASGGGAKTPQKKPKLSEDDEDDDEDEDDDEDDEDDLDDDEEEIKTPMKKPAREPAGKNMQKAKQNGKDSKPSTPASKTKTPDSKKDKSLTPKTPKVPLSLEEIKAKMQASVDKGCSLPKLEPKFANYVKNCFRTEDQKVIQALWQWRQTL |
adenohypophysis development adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway growth hormone secretion hormone secretion multicellular organism growth negative regulation of cardiac muscle cell apoptotic process positive regulation of cAMP-mediated signaling positive regulation of cell population proliferation positive regulation of circadian sleep/wake cycle, non-REM sleep positive regulation of cytosolic calcium ion concentration positive regulation of DNA-templated transcription positive regulation of growth hormone secretion positive regulation of hormone secretion positive regulation of multicellular organism growth response to food | axon terminus; extracellular space; perikaryon; terminal bouton | growth hormone-releasing hormone activity growth hormone-releasing hormone receptor binding neuropeptide hormone activity peptide hormone receptor binding | Mus musculus | Reference proteome Secreted Signal | MLLWVLFVIL | MLLWVLFVILILTSGSHCSLPPSPPFRMQRHVDAIFTTNYRKLLSQLYARKVIQDIMNKQGERIQEQRARLSRQEDSMWTEDKQMTLESILQGFPRMKPSADA | adenohypophysis development adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway growth hormone secretion hormone secretion multicellular organism growth negative regulation of cardiac muscle cell apoptotic process positive regulation of cAMP-mediated signaling positive regulation of cell population proliferation positive regulation of circadian sleep/wake cycle, non-REM sleep positive regulation of cytosolic calcium ion concentration positive regulation of DNA-templated transcription positive regulation of growth hormone secretion positive regulation of hormone secretion positive regulation of multicellular organism growth response to food axon terminus; extracellular space; perikaryon; terminal bouton growth hormone-releasing hormone activity growth hormone-releasing hormone receptor binding neuropeptide hormone activity peptide hormone receptor binding Mus musculus Reference proteome Secreted Signal MLLWVLFVIL MLLWVLFVILILTSGSHCSLPPSPPFRMQRHVDAIFTTNYRKLLSQLYARKVIQDIMNKQGERIQEQRARLSRQEDSMWTEDKQMTLESILQGFPRMKPSADA |
apoptotic process cell-cell adhesion heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules myoblast differentiation negative regulation of cell-substrate adhesion negative regulation of neuron projection development plasma cell differentiation positive regulation of apoptotic process positive regulation of erythrocyte aggregation positive regulation of inflammatory response positive regulation of viral entry into host cell T cell costimulation | cell surface; collagen-containing extracellular matrix; cytosol; extracellular region; extracellular space; galectin complex | carbohydrate binding galactose binding identical protein binding lactose binding laminin binding | Mus musculus | 3D-structure Acetylation Apoptosis Cytoplasm Extracellular matrix Lectin Phosphoprotein Reference proteome Secreted | MACGLVASNL | MACGLVASNLNLKPGECLKVRGEVASDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNTKEDGTWGTEHREPAFPFQPGSITEVCITFDQADLTIKLPDGHEFKFPNRLNMEAINYMAADGDFKIKCVAFE | apoptotic process cell-cell adhesion heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules myoblast differentiation negative regulation of cell-substrate adhesion negative regulation of neuron projection development plasma cell differentiation positive regulation of apoptotic process positive regulation of erythrocyte aggregation positive regulation of inflammatory response positive regulation of viral entry into host cell T cell costimulation cell surface; collagen-containing extracellular matrix; cytosol; extracellular region; extracellular space; galectin complex carbohydrate binding galactose binding identical protein binding lactose binding laminin binding Mus musculus 3D-structure Acetylation Apoptosis Cytoplasm Extracellular matrix Lectin Phosphoprotein Reference proteome Secreted MACGLVASNL MACGLVASNLNLKPGECLKVRGEVASDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNTKEDGTWGTEHREPAFPFQPGSITEVCITFDQADLTIKLPDGHEFKFPNRLNMEAINYMAADGDFKIKCVAFE |
nuclear capsid assembly proteolysis viral release from host cell | host cell cytoplasm; host cell nucleus | identical protein binding serine-type endopeptidase activity | Simian cytomegalovirus | Alternative promoter usage Host cytoplasm Host nucleus Hydrolase Phosphoprotein Protease Serine protease Viral capsid assembly Viral release from host cell | MADPVYVGGF | MADPVYVGGFLVRYDEPPGEAELFLPSGVVDRWLRDCRGPLPLNVNHDESATVGYVAGLQNVRAGLFCLGRVTSPKFLDIVQKASEKSELVSRGPPSESSLRPDGVLEFLSGSYSGLSLSSRRDINAADGAAGDAETACFKHVALCSVGRRRGTLAVYGRQPDWVMERFPDLTEADREALRNQLSGSGEVAAKESAESSAAAAVDPFQSDSYGLLGNSVDALYIQERLPKLRYDKRLVGVTARESYVKASVSPAEQETCDIKVEKERPKEPEQSHVPTESMSHPMSAVATPAASTVAPSQAPLALAHDGVYLPKDAFFSLIGASRPLAEAAGARAAYPAVPPPPAYPVMNYEDPSSRHFDYSAWLRRPAYDAVPPLPPPPVMPMPYRRRDPMMEEAERAAWERGYAPSAYDHYVNNGSWSRSRSGALKRRRERDASSDEEEDMSFPGEADHGKARKRLKAHHGRDNNNSGSDAKGDRYDDIREALQELKREMLAVRQIAPAALLAPAQLATPVASPTTTTSHQAEASEPQASTAAAAPSTASSHGSKSAERGVVNASCRVAPPLEAVNPPKDMVDLNRRLFVAALNKME | nuclear capsid assembly proteolysis viral release from host cell host cell cytoplasm; host cell nucleus identical protein binding serine-type endopeptidase activity Simian cytomegalovirus Alternative promoter usage Host cytoplasm Host nucleus Hydrolase Phosphoprotein Protease Serine protease Viral capsid assembly Viral release from host cell MADPVYVGGF MADPVYVGGFLVRYDEPPGEAELFLPSGVVDRWLRDCRGPLPLNVNHDESATVGYVAGLQNVRAGLFCLGRVTSPKFLDIVQKASEKSELVSRGPPSESSLRPDGVLEFLSGSYSGLSLSSRRDINAADGAAGDAETACFKHVALCSVGRRRGTLAVYGRQPDWVMERFPDLTEADREALRNQLSGSGEVAAKESAESSAAAAVDPFQSDSYGLLGNSVDALYIQERLPKLRYDKRLVGVTARESYVKASVSPAEQETCDIKVEKERPKEPEQSHVPTESMSHPMSAVATPAASTVAPSQAPLALAHDGVYLPKDAFFSLIGASRPLAEAAGARAAYPAVPPPPAYPVMNYEDPSSRHFDYSAWLRRPAYDAVPPLPPPPVMPMPYRRRDPMMEEAERAAWERGYAPSAYDHYVNNGSWSRSRSGALKRRRERDASSDEEEDMSFPGEADHGKARKRLKAHHGRDNNNSGSDAKGDRYDDIREALQELKREMLAVRQIAPAALLAPAQLATPVASPTTTTSHQAEASEPQASTAAAAPSTASSHGSKSAERGVVNASCRVAPPLEAVNPPKDMVDLNRRLFVAALNKME |
cardiac epithelial to mesenchymal transition cell activation cell-cell junction organization detection of hypoxia embryonic digestive tract development epithelial to mesenchymal transition involved in endocardial cushion formation face morphogenesis mesenchyme migration negative regulation of cell population proliferation negative regulation of macrophage cytokine production nervous system development positive regulation of cell division positive regulation of cell migration positive regulation of cell population proliferation positive regulation of collagen biosynthetic process positive regulation of DNA-templated transcription positive regulation of epithelial to mesenchymal transition regulation of cell population proliferation response to hypoxia response to progesterone salivary gland morphogenesis spleen development transforming growth factor beta receptor signaling pathway | extracellular matrix; extracellular space | cytokine activity growth factor activity identical protein binding transforming growth factor beta binding type I transforming growth factor beta receptor binding type II transforming growth factor beta receptor binding type III transforming growth factor beta receptor binding | Gallus gallus | Cleavage on pair of basic residues Disulfide bond Extracellular matrix Glycoprotein Growth factor Mitogen Reference proteome Secreted Signal | MKMYAQRALV | MKMYAQRALVLLSLLSFATVSLALSSCTTLDLEHIKKKRVEAIRGQILSKLRLTSPPESVGPAHVPYQILALYNSTRELLEEMEEEKEESCSQENTESEYYAKEIHKFDMIQGLPEHNELGICPKGVTSNVFRFNVSSAEKNSTNLFRAEFRVLRVPNPSSKRSEQRIELFQILRPDEHIAKQRYLSGRNVQTRGSPEWLSFDVTDTVREWLLHRESNLGLEISIHCPCHTFQPNGDILENLHEVLEIKFKGIDSEDDYGRGDLGRLKKQKDLHNPHLILMMLPPHRLESPTLGGQRKKRALDTNYCFRNLEENCCVRPLYIELPTDLGWKWVHEPKGYFANFCSGPCPYLRSADTTHSTVLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS | cardiac epithelial to mesenchymal transition cell activation cell-cell junction organization detection of hypoxia embryonic digestive tract development epithelial to mesenchymal transition involved in endocardial cushion formation face morphogenesis mesenchyme migration negative regulation of cell population proliferation negative regulation of macrophage cytokine production nervous system development positive regulation of cell division positive regulation of cell migration positive regulation of cell population proliferation positive regulation of collagen biosynthetic process positive regulation of DNA-templated transcription positive regulation of epithelial to mesenchymal transition regulation of cell population proliferation response to hypoxia response to progesterone salivary gland morphogenesis spleen development transforming growth factor beta receptor signaling pathway extracellular matrix; extracellular space cytokine activity growth factor activity identical protein binding transforming growth factor beta binding type I transforming growth factor beta receptor binding type II transforming growth factor beta receptor binding type III transforming growth factor beta receptor binding Gallus gallus Cleavage on pair of basic residues Disulfide bond Extracellular matrix Glycoprotein Growth factor Mitogen Reference proteome Secreted Signal MKMYAQRALV MKMYAQRALVLLSLLSFATVSLALSSCTTLDLEHIKKKRVEAIRGQILSKLRLTSPPESVGPAHVPYQILALYNSTRELLEEMEEEKEESCSQENTESEYYAKEIHKFDMIQGLPEHNELGICPKGVTSNVFRFNVSSAEKNSTNLFRAEFRVLRVPNPSSKRSEQRIELFQILRPDEHIAKQRYLSGRNVQTRGSPEWLSFDVTDTVREWLLHRESNLGLEISIHCPCHTFQPNGDILENLHEVLEIKFKGIDSEDDYGRGDLGRLKKQKDLHNPHLILMMLPPHRLESPTLGGQRKKRALDTNYCFRNLEENCCVRPLYIELPTDLGWKWVHEPKGYFANFCSGPCPYLRSADTTHSTVLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS |
apoptotic cell clearance arachidonic acid metabolic process bone mineralization cellular response to calcium ion cellular response to interleukin-13 fatty acid oxidation hepoxilin biosynthetic process inflammatory response linoleic acid metabolic process lipid metabolic process lipid oxidation lipoxin A4 biosynthetic process lipoxygenase pathway long-chain fatty acid biosynthetic process negative regulation of adaptive immune response ossification phosphatidylethanolamine biosynthetic process positive regulation of actin filament polymerization positive regulation of cell-substrate adhesion positive regulation of ERK1 and ERK2 cascade regulation of engulfment of apoptotic cell regulation of inflammatory response regulation of peroxisome proliferator activated receptor signaling pathway response to endoplasmic reticulum stress wound healing | cytoplasmic side of plasma membrane; cytosol; lipid droplet; membrane; plasma membrane | arachidonate 12(S)-lipoxygenase activity arachidonate 15-lipoxygenase activity iron ion binding linoleate 13S-lipoxygenase activity phosphatidylinositol-4,5-bisphosphate binding | Homo sapiens | Alternative splicing Calcium Cell membrane Cytoplasm Dioxygenase Direct protein sequencing Fatty acid metabolism Iron Lipid droplet Lipid metabolism Lipid-binding Membrane Metal-binding Oxidoreductase Reference proteome | MGLYRIRVST | MGLYRIRVSTGASLYAGSNNQVQLWLVGQHGEAALGKRLWPARGKETELKVEVPEYLGPLLFVKLRKRHLLKDDAWFCNWISVQGPGAGDEVRFPCYRWVEGNGVLSLPEGTGRTVGEDPQGLFQKHREEELEERRKLYRWGNWKDGLILNMAGAKLYDLPVDERFLEDKRVDFEVSLAKGLADLAIKDSLNVLTCWKDLDDFNRIFWCGQSKLAERVRDSWKEDALFGYQFLNGANPVVLRRSAHLPARLVFPPGMEELQAQLEKELEGGTLFEADFSLLDGIKANVILCSQQHLAAPLVMLKLQPDGKLLPMVIQLQLPRTGSPPPPLFLPTDPPMAWLLAKCWVRSSDFQLHELQSHLLRGHLMAEVIVVATMRCLPSIHPIFKLIIPHLRYTLEINVRARTGLVSDMGIFDQIMSTGGGGHVQLLKQAGAFLTYSSFCPPDDLADRGLLGVKSSFYAQDALRLWEIIYRYVEGIVSLHYKTDVAVKDDPELQTWCREITEIGLQGAQDRGFPVSLQARDQVCHFVTMCIFTCTGQHASVHLGQLDWYSWVPNAPCTMRLPPPTTKDATLETVMATLPNFHQASLQMSITWQLGRRQPVMVAVGQHEEEYFSGPEPKAVLKKFREELAALDKEIEIRNAKLDMPYEYLRPSVVENSVAI | apoptotic cell clearance arachidonic acid metabolic process bone mineralization cellular response to calcium ion cellular response to interleukin-13 fatty acid oxidation hepoxilin biosynthetic process inflammatory response linoleic acid metabolic process lipid metabolic process lipid oxidation lipoxin A4 biosynthetic process lipoxygenase pathway long-chain fatty acid biosynthetic process negative regulation of adaptive immune response ossification phosphatidylethanolamine biosynthetic process positive regulation of actin filament polymerization positive regulation of cell-substrate adhesion positive regulation of ERK1 and ERK2 cascade regulation of engulfment of apoptotic cell regulation of inflammatory response regulation of peroxisome proliferator activated receptor signaling pathway response to endoplasmic reticulum stress wound healing cytoplasmic side of plasma membrane; cytosol; lipid droplet; membrane; plasma membrane arachidonate 12(S)-lipoxygenase activity arachidonate 15-lipoxygenase activity iron ion binding linoleate 13S-lipoxygenase activity phosphatidylinositol-4,5-bisphosphate binding Homo sapiens Alternative splicing Calcium Cell membrane Cytoplasm Dioxygenase Direct protein sequencing Fatty acid metabolism Iron Lipid droplet Lipid metabolism Lipid-binding Membrane Metal-binding Oxidoreductase Reference proteome MGLYRIRVST MGLYRIRVSTGASLYAGSNNQVQLWLVGQHGEAALGKRLWPARGKETELKVEVPEYLGPLLFVKLRKRHLLKDDAWFCNWISVQGPGAGDEVRFPCYRWVEGNGVLSLPEGTGRTVGEDPQGLFQKHREEELEERRKLYRWGNWKDGLILNMAGAKLYDLPVDERFLEDKRVDFEVSLAKGLADLAIKDSLNVLTCWKDLDDFNRIFWCGQSKLAERVRDSWKEDALFGYQFLNGANPVVLRRSAHLPARLVFPPGMEELQAQLEKELEGGTLFEADFSLLDGIKANVILCSQQHLAAPLVMLKLQPDGKLLPMVIQLQLPRTGSPPPPLFLPTDPPMAWLLAKCWVRSSDFQLHELQSHLLRGHLMAEVIVVATMRCLPSIHPIFKLIIPHLRYTLEINVRARTGLVSDMGIFDQIMSTGGGGHVQLLKQAGAFLTYSSFCPPDDLADRGLLGVKSSFYAQDALRLWEIIYRYVEGIVSLHYKTDVAVKDDPELQTWCREITEIGLQGAQDRGFPVSLQARDQVCHFVTMCIFTCTGQHASVHLGQLDWYSWVPNAPCTMRLPPPTTKDATLETVMATLPNFHQASLQMSITWQLGRRQPVMVAVGQHEEEYFSGPEPKAVLKKFREELAALDKEIEIRNAKLDMPYEYLRPSVVENSVAI |
actin filament polymerization adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway aggregation involved in sorocarp development chemotaxis phagocytosis regulation of DNA-templated transcription regulation of protein export from nucleus response to bacterium small GTPase mediated signal transduction | cytosol; heterotrimeric G-protein complex; plasma membrane | G protein activity G protein-coupled receptor binding G-protein beta-subunit binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity GTPase regulator activity guanyl-nucleotide exchange factor adaptor activity metal ion binding | Dictyostelium discoideum | GTP-binding Lipoprotein Magnesium Metal-binding Myristate Nucleotide-binding Palmitate Phosphoprotein Reference proteome Transducer | MGICASSMEG | MGICASSMEGEKTNTDINLSIEKERKKKHNEVKLLLLGAGESGKSTISKQMKIIHQSGYSNEERKEFKPIITRNILDNMRVLLDGMGRLGMTIDPSNSDAAVMIKELTSLQASIVTDCWGELNEDQGKKIKALWTDPGVKQAMRRANEFSTLPDSAPYFFDSIDRMTSPVYIPTDQDILHTRVMTRGVHETNFEIGKIKFRLVDVGGQRSERKKWLSCFDDVTAVVFCVALSEYDLLLYEDNSTNRMLESLRVFSDVCNSWFVNTPIILFLNKSDLFREKIKHVDLSETFPEYKGGRDYERASNYIKERFWQINKTEQKAIYSHITCATDTNNIRVVFEAVKDIIFTQCVMKAGLYS | actin filament polymerization adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway aggregation involved in sorocarp development chemotaxis phagocytosis regulation of DNA-templated transcription regulation of protein export from nucleus response to bacterium small GTPase mediated signal transduction cytosol; heterotrimeric G-protein complex; plasma membrane G protein activity G protein-coupled receptor binding G-protein beta-subunit binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity GTPase regulator activity guanyl-nucleotide exchange factor adaptor activity metal ion binding Dictyostelium discoideum GTP-binding Lipoprotein Magnesium Metal-binding Myristate Nucleotide-binding Palmitate Phosphoprotein Reference proteome Transducer MGICASSMEG MGICASSMEGEKTNTDINLSIEKERKKKHNEVKLLLLGAGESGKSTISKQMKIIHQSGYSNEERKEFKPIITRNILDNMRVLLDGMGRLGMTIDPSNSDAAVMIKELTSLQASIVTDCWGELNEDQGKKIKALWTDPGVKQAMRRANEFSTLPDSAPYFFDSIDRMTSPVYIPTDQDILHTRVMTRGVHETNFEIGKIKFRLVDVGGQRSERKKWLSCFDDVTAVVFCVALSEYDLLLYEDNSTNRMLESLRVFSDVCNSWFVNTPIILFLNKSDLFREKIKHVDLSETFPEYKGGRDYERASNYIKERFWQINKTEQKAIYSHITCATDTNNIRVVFEAVKDIIFTQCVMKAGLYS |
intracellular estrogen receptor signaling pathway response to cadmium ion response to estradiol response to testosterone | nucleus | androgen binding DNA binding DNA-binding transcription factor activity estradiol binding estrogen response element binding nuclear estrogen receptor activity nuclear estrogen receptor binding protein homodimerization activity steroid hormone binding zinc ion binding | Oncorhynchus mykiss | Alternative splicing DNA-binding Lipid-binding Metal-binding Nucleus Receptor Steroid-binding Transcription Transcription regulation Zinc Zinc-finger | MLVRQSHTQI | MLVRQSHTQISKPLGAPLRSRTTLESHVISPPKLSPQQPTTPNSNMYPEETRGGGGAAAFNYLDGGYDYTAPAQGPAPLYYSTTPQDAHGPPSDGSMQSLGSSPTGPLVFVSSSPQLSPQLSPFLHPPSHHGLPSQSYYLETSSTPLYRSSVVTNQLSASEEKLCIASDRQQSYSAAGSGVRVFEMANETRYCAVCSDFASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTMDRNRRKSCQACRLRKCYEVGMVKGGLRKDRGGRVLRKDKRYCGPAGDREKPYGDLEHRTAPPQDGGRNSSSSLNGGGGWRGPRITMPPEQVLFLLQGAEPPALCSRQKVARPYTEVTMMTLLTSMADKELVHMIAWAKKVPGFQELSLHDQVQLLESSWLEVLMIGLIWRSIHCPGKLIFAQDLILDRSEGDCVEGMAEIFDMLLATVSRFRMLKLKPEEFVCLKAIILLNSGAFSFCSNSVESLHNSSAVESMLDNITDALIHHISHSGASVQQQPRRQAQLLLLLSHIRHMSNKGMEHLYSIKCKNKVPLYDLLLEMLDGHRLQSPGKVAQAGEQTEGPSTTTTTSTGSSIGPMRGSQDTHIRSPGSGVLQYGSPSSDQMPIP | intracellular estrogen receptor signaling pathway response to cadmium ion response to estradiol response to testosterone nucleus androgen binding DNA binding DNA-binding transcription factor activity estradiol binding estrogen response element binding nuclear estrogen receptor activity nuclear estrogen receptor binding protein homodimerization activity steroid hormone binding zinc ion binding Oncorhynchus mykiss Alternative splicing DNA-binding Lipid-binding Metal-binding Nucleus Receptor Steroid-binding Transcription Transcription regulation Zinc Zinc-finger MLVRQSHTQI MLVRQSHTQISKPLGAPLRSRTTLESHVISPPKLSPQQPTTPNSNMYPEETRGGGGAAAFNYLDGGYDYTAPAQGPAPLYYSTTPQDAHGPPSDGSMQSLGSSPTGPLVFVSSSPQLSPQLSPFLHPPSHHGLPSQSYYLETSSTPLYRSSVVTNQLSASEEKLCIASDRQQSYSAAGSGVRVFEMANETRYCAVCSDFASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTMDRNRRKSCQACRLRKCYEVGMVKGGLRKDRGGRVLRKDKRYCGPAGDREKPYGDLEHRTAPPQDGGRNSSSSLNGGGGWRGPRITMPPEQVLFLLQGAEPPALCSRQKVARPYTEVTMMTLLTSMADKELVHMIAWAKKVPGFQELSLHDQVQLLESSWLEVLMIGLIWRSIHCPGKLIFAQDLILDRSEGDCVEGMAEIFDMLLATVSRFRMLKLKPEEFVCLKAIILLNSGAFSFCSNSVESLHNSSAVESMLDNITDALIHHISHSGASVQQQPRRQAQLLLLLSHIRHMSNKGMEHLYSIKCKNKVPLYDLLLEMLDGHRLQSPGKVAQAGEQTEGPSTTTTTSTGSSIGPMRGSQDTHIRSPGSGVLQYGSPSSDQMPIP |
cellular response to nitric oxide cGMP biosynthetic process cGMP-mediated signaling nitric oxide-cGMP-mediated signaling pathway response to oxygen levels trans-synaptic signaling by nitric oxide, modulating synaptic transmission | cytoplasm; guanylate cyclase complex, soluble; synapse | GTP binding guanylate cyclase activity heme binding metal ion binding | Bos taurus | cGMP biosynthesis Cytoplasm Direct protein sequencing GTP-binding Heme Iron Lyase Metal-binding Nucleotide-binding Reference proteome | MYGFVNHALE | MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDADKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKSECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMTPENSDPQFHLEHRGPVSMKGKKEPMQVWFLSRKNTGTEETEQDEN | cellular response to nitric oxide cGMP biosynthetic process cGMP-mediated signaling nitric oxide-cGMP-mediated signaling pathway response to oxygen levels trans-synaptic signaling by nitric oxide, modulating synaptic transmission cytoplasm; guanylate cyclase complex, soluble; synapse GTP binding guanylate cyclase activity heme binding metal ion binding Bos taurus cGMP biosynthesis Cytoplasm Direct protein sequencing GTP-binding Heme Iron Lyase Metal-binding Nucleotide-binding Reference proteome MYGFVNHALE MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDADKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKSECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMTPENSDPQFHLEHRGPVSMKGKKEPMQVWFLSRKNTGTEETEQDEN |
cartilage development cell adhesion cell migration cell-cell adhesion cell-matrix adhesion cellular response to fibroblast growth factor stimulus cytokine-mediated signaling pathway hyaluronan catabolic process inflammatory response monocyte aggregation negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process negative regulation of DNA damage response, signal transduction by p53 class mediator negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator positive regulation of ERK1 and ERK2 cascade positive regulation of heterotypic cell-cell adhesion positive regulation of monocyte aggregation positive regulation of peptidyl-serine phosphorylation positive regulation of peptidyl-tyrosine phosphorylation regulation of lamellipodium morphogenesis T cell activation wound healing, spreading of cells | apical plasma membrane; basolateral plasma membrane; cell projection; cell surface; cytosol; extracellular exosome; focal adhesion; Golgi apparatus; lamellipodium membrane; macrophage migration inhibitory factor receptor complex; microvillus; plasma membrane; secretory granule membrane | collagen binding hyaluronic acid binding transmembrane signaling receptor activity | Homo sapiens | 3D-structure Alternative splicing Blood group antigen Cell adhesion Cell membrane Cell projection Direct protein sequencing Disulfide bond Glycoprotein Membrane Phosphoprotein Proteoglycan Receptor Reference proteome Secreted Signal Transmembrane Transmembrane helix | MDKFWWHAAW | MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTLPTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQNVDMKIGV | cartilage development cell adhesion cell migration cell-cell adhesion cell-matrix adhesion cellular response to fibroblast growth factor stimulus cytokine-mediated signaling pathway hyaluronan catabolic process inflammatory response monocyte aggregation negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process negative regulation of DNA damage response, signal transduction by p53 class mediator negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator positive regulation of ERK1 and ERK2 cascade positive regulation of heterotypic cell-cell adhesion positive regulation of monocyte aggregation positive regulation of peptidyl-serine phosphorylation positive regulation of peptidyl-tyrosine phosphorylation regulation of lamellipodium morphogenesis T cell activation wound healing, spreading of cells apical plasma membrane; basolateral plasma membrane; cell projection; cell surface; cytosol; extracellular exosome; focal adhesion; Golgi apparatus; lamellipodium membrane; macrophage migration inhibitory factor receptor complex; microvillus; plasma membrane; secretory granule membrane collagen binding hyaluronic acid binding transmembrane signaling receptor activity Homo sapiens 3D-structure Alternative splicing Blood group antigen Cell adhesion Cell membrane Cell projection Direct protein sequencing Disulfide bond Glycoprotein Membrane Phosphoprotein Proteoglycan Receptor Reference proteome Secreted Signal Transmembrane Transmembrane helix MDKFWWHAAW MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTLPTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQNVDMKIGV |
cellular response to estradiol stimulus muscle cell fate commitment muscle organ development positive regulation of myoblast differentiation positive regulation of skeletal muscle fiber development positive regulation of snRNA transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II skeletal muscle cell differentiation | nucleus; transcription regulator complex | bHLH transcription factor binding DNA-binding transcription activator activity DNA-binding transcription factor activity, RNA polymerase II-specific E-box binding identical protein binding promoter-specific chromatin binding protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding | Gallus gallus | Activator Developmental protein Differentiation DNA-binding Myogenesis Nucleus Reference proteome Transcription Transcription regulation | MDLLGPMEMT | MDLLGPMEMTEGSLCSFTAADDFYDDPCFNTSDMHFFEDLDPRLVHVGGLLKPEEHPHTRAPPREPTEEEHVRAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRERRRLSKVNEAFETLKRCTSTNPNQRLPKVEILRNAIRYIESLQALLREQEDAYYPVLEHYSGESDASSPRSNCSDGMMEYSGPPCSSRRRNSYDSSYYTESPNDPKHGKSSVVSSLDCLSSIVERISTDNSTCPILPPAEAVAEGSPCSPQEGGNLSDSGAQIPSPTNCTPLPQESSSSSSSNPIYQVL | cellular response to estradiol stimulus muscle cell fate commitment muscle organ development positive regulation of myoblast differentiation positive regulation of skeletal muscle fiber development positive regulation of snRNA transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II skeletal muscle cell differentiation nucleus; transcription regulator complex bHLH transcription factor binding DNA-binding transcription activator activity DNA-binding transcription factor activity, RNA polymerase II-specific E-box binding identical protein binding promoter-specific chromatin binding protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding Gallus gallus Activator Developmental protein Differentiation DNA-binding Myogenesis Nucleus Reference proteome Transcription Transcription regulation MDLLGPMEMT MDLLGPMEMTEGSLCSFTAADDFYDDPCFNTSDMHFFEDLDPRLVHVGGLLKPEEHPHTRAPPREPTEEEHVRAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRERRRLSKVNEAFETLKRCTSTNPNQRLPKVEILRNAIRYIESLQALLREQEDAYYPVLEHYSGESDASSPRSNCSDGMMEYSGPPCSSRRRNSYDSSYYTESPNDPKHGKSSVVSSLDCLSSIVERISTDNSTCPILPPAEAVAEGSPCSPQEGGNLSDSGAQIPSPTNCTPLPQESSSSSSSNPIYQVL |
glyoxylate cycle tricarboxylic acid cycle | cytoplasm | isocitrate dehydrogenase (NADP+) activity metal ion binding | Azotobacter vinelandii | 3D-structure Cytoplasm Direct protein sequencing Glyoxylate bypass Magnesium Manganese Metal-binding NADP Oxidoreductase Phosphoprotein Tricarboxylic acid cycle | MSTPKIIYTL | MSTPKIIYTLTDEAPALATYSLLPIIKAFTGSSGIAVETRDISLAGRLIATFPEYLTDTQKISDDLAELGKLATTPDANIIKLPNISASVPQLKAAIKELQQQGYKLPDYPEEPKTDTEKDVKARYDKIKGSAVNPVLREGNSDRRAPLSVKNYARKHPHKMGAWSADSKSHVAHMDNGDFYGSEKAALIGAPGSVKIELIAKDGSSTVLKAKTSVQAGEIIDSSVMSKNALRNFIAAEIEDAKKQGVLLSVHLKATMMKVSDPIMFGQIVSEFYKDALTKHAEVLKQIGFDVNNGIGDLYARIKTLPEAKQKEIEADIQAVYAQRPQLAMVNSDKGITNLHVPSDVIVDASMPAMIRDSGKMWGPDGKLHDTKAVIPDRCYAGVYQVVIEDCKQHGAFDPTTMGSVPNVGLMAQKAEEYGSHDKTFQIPADGVVRVTDESGKLLLEQSVEAGDIWRMCQAKDAPIQDWVKLAVNRARATNTPAVFWLDPARAHDAQVIAKVERYLKDYDTSGLDIRILSPVEATRFSLARIREGKDTISVTGNVLRDYLTDLFPIMELGTSAKMLSIVPLMSGGGLFETGAGGSAPKHVQQFLEEGYLRWDSLGEFLALAASLEHLGNAYKNPKALVLASTLDQATGKILDNNKSPARKVGEIDNRGSHFYLALYWAQALAAQTEDKELQAQFTGIAKALTDNETKIVGELAAAQGKPVDIAGYYHPNTDLTSKAIRPSATFNAALAPLA | glyoxylate cycle tricarboxylic acid cycle cytoplasm isocitrate dehydrogenase (NADP+) activity metal ion binding Azotobacter vinelandii3D-structure Cytoplasm Direct protein sequencing Glyoxylate bypass Magnesium Manganese Metal-binding NADP Oxidoreductase Phosphoprotein Tricarboxylic acid cycle MSTPKIIYTL MSTPKIIYTLTDEAPALATYSLLPIIKAFTGSSGIAVETRDISLAGRLIATFPEYLTDTQKISDDLAELGKLATTPDANIIKLPNISASVPQLKAAIKELQQQGYKLPDYPEEPKTDTEKDVKARYDKIKGSAVNPVLREGNSDRRAPLSVKNYARKHPHKMGAWSADSKSHVAHMDNGDFYGSEKAALIGAPGSVKIELIAKDGSSTVLKAKTSVQAGEIIDSSVMSKNALRNFIAAEIEDAKKQGVLLSVHLKATMMKVSDPIMFGQIVSEFYKDALTKHAEVLKQIGFDVNNGIGDLYARIKTLPEAKQKEIEADIQAVYAQRPQLAMVNSDKGITNLHVPSDVIVDASMPAMIRDSGKMWGPDGKLHDTKAVIPDRCYAGVYQVVIEDCKQHGAFDPTTMGSVPNVGLMAQKAEEYGSHDKTFQIPADGVVRVTDESGKLLLEQSVEAGDIWRMCQAKDAPIQDWVKLAVNRARATNTPAVFWLDPARAHDAQVIAKVERYLKDYDTSGLDIRILSPVEATRFSLARIREGKDTISVTGNVLRDYLTDLFPIMELGTSAKMLSIVPLMSGGGLFETGAGGSAPKHVQQFLEEGYLRWDSLGEFLALAASLEHLGNAYKNPKALVLASTLDQATGKILDNNKSPARKVGEIDNRGSHFYLALYWAQALAAQTEDKELQAQFTGIAKALTDNETKIVGELAAAQGKPVDIAGYYHPNTDLTSKAIRPSATFNAALAPLA |
cellular response to gamma radiation cellular senescence cerebral cortex development DNA damage checkpoint signaling DNA damage response double-strand break repair double-strand break repair via homologous recombination meiotic cell cycle nucleosome assembly positive regulation of DNA repair response to ionizing radiation spermatogenesis | centrosome; condensed nuclear chromosome; extracellular exosome; male germ cell nucleus; nuclear speck; nucleoplasm; nucleosome; nucleus; replication fork; site of DNA damage; site of double-strand break; XY body | damaged DNA binding DNA binding enzyme binding histone binding protein heterodimerization activity structural constituent of chromatin | Homo sapiens | 3D-structure Acetylation Cell cycle Chromosome DNA damage DNA recombination DNA repair DNA-binding Host-virus interaction Isopeptide bond Meiosis Nucleosome core Nucleus Phosphoprotein Reference proteome Ubl conjugation | MSGRGKTGGK | MSGRGKTGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGHYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTSATVGPKAPSGGKKATQASQEY | cellular response to gamma radiation cellular senescence cerebral cortex development DNA damage checkpoint signaling DNA damage response double-strand break repair double-strand break repair via homologous recombination meiotic cell cycle nucleosome assembly positive regulation of DNA repair response to ionizing radiation spermatogenesis centrosome; condensed nuclear chromosome; extracellular exosome; male germ cell nucleus; nuclear speck; nucleoplasm; nucleosome; nucleus; replication fork; site of DNA damage; site of double-strand break; XY body damaged DNA binding DNA binding enzyme binding histone binding protein heterodimerization activity structural constituent of chromatin Homo sapiens 3D-structure Acetylation Cell cycle Chromosome DNA damage DNA recombination DNA repair DNA-binding Host-virus interaction Isopeptide bond Meiosis Nucleosome core Nucleus Phosphoprotein Reference proteome Ubl conjugation MSGRGKTGGK MSGRGKTGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGHYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTSATVGPKAPSGGKKATQASQEY |
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules calcium-mediated signaling using intracellular calcium source cell adhesion defense response to Gram-negative bacterium heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules inflammatory response leukocyte cell-cell adhesion leukocyte tethering or rolling positive regulation of leukocyte migration positive regulation of leukocyte tethering or rolling positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of platelet activation regulation of integrin activation response to cytokine response to lipopolysaccharide | external side of plasma membrane; extracellular space; plasma membrane; platelet alpha granule membrane; platelet dense granule membrane | calcium ion binding calcium-dependent protein binding fucose binding glycosphingolipid binding heparin binding lipopolysaccharide binding oligosaccharide binding sialic acid binding | Homo sapiens | 3D-structure Calcium Cell adhesion Cell membrane Disulfide bond EGF-like domain Glycoprotein Lectin Lipoprotein Membrane Metal-binding Palmitate Reference proteome Repeat Signal Sushi Transmembrane Transmembrane helix | MANCQIAILY | MANCQIAILYQRFQRVVFGISQLLCFSALISELTNQKEVAAWTYHYSTKAYSWNISRKYCQNRYTDLVAIQNKNEIDYLNKVLPYYSSYYWIGIRKNNKTWTWVGTKKALTNEAENWADNEPNNKRNNEDCVEIYIKSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGNYTCSCYPGFYGPECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQAGPLTIQEALTYFGGAVASTIGLIMGGTLLALLRKRFRQKDDGKCPLNPHSHLGTYGVFTNAAFDPSP | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules calcium-mediated signaling using intracellular calcium source cell adhesion defense response to Gram-negative bacterium heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules inflammatory response leukocyte cell-cell adhesion leukocyte tethering or rolling positive regulation of leukocyte migration positive regulation of leukocyte tethering or rolling positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of platelet activation regulation of integrin activation response to cytokine response to lipopolysaccharide external side of plasma membrane; extracellular space; plasma membrane; platelet alpha granule membrane; platelet dense granule membrane calcium ion binding calcium-dependent protein binding fucose binding glycosphingolipid binding heparin binding lipopolysaccharide binding oligosaccharide binding sialic acid binding Homo sapiens 3D-structure Calcium Cell adhesion Cell membrane Disulfide bond EGF-like domain Glycoprotein Lectin Lipoprotein Membrane Metal-binding Palmitate Reference proteome Repeat Signal Sushi Transmembrane Transmembrane helix MANCQIAILY MANCQIAILYQRFQRVVFGISQLLCFSALISELTNQKEVAAWTYHYSTKAYSWNISRKYCQNRYTDLVAIQNKNEIDYLNKVLPYYSSYYWIGIRKNNKTWTWVGTKKALTNEAENWADNEPNNKRNNEDCVEIYIKSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGNYTCSCYPGFYGPECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQAGPLTIQEALTYFGGAVASTIGLIMGGTLLALLRKRFRQKDDGKCPLNPHSHLGTYGVFTNAAFDPSP |
glycolytic process lactate metabolic process pyruvate metabolic process | cytoplasm | L-lactate dehydrogenase activity | Thermotoga maritima | 3D-structure Allosteric enzyme Cytoplasm Direct protein sequencing NAD Oxidoreductase Phosphoprotein Reference proteome | MKIGIVGLGR | MKIGIVGLGRVGSSTAFALLMKGFAREMVLIDVDKKRAEGDALDLIHGTPFTRRANIYAGDYADLKGSDVVIVAAGVPQKPGETRLQLLGRNARVMKEIARNVSKYAPDSIVIVVTNPVDVLTYFFLKESGMDPRKVFGSGTVLDTARLRTLIAQHCGFSPRSVHVYVIGEHGDSEVPVWSGAMIGGIPLQNMCQICQKCDSKILENFAEKTKRAAYEIIERKGATHYAIALAVADIVESIFFDEKRVLTLSVYLEDYLGVKDLCISVPVTLGKHGVERILELNLNEEELEAFRKSASILKNAINEITAEENKHQNTSG | glycolytic process lactate metabolic process pyruvate metabolic process cytoplasm L-lactate dehydrogenase activity Thermotoga maritima 3D-structure Allosteric enzyme Cytoplasm Direct protein sequencing NAD Oxidoreductase Phosphoprotein Reference proteome MKIGIVGLGR MKIGIVGLGRVGSSTAFALLMKGFAREMVLIDVDKKRAEGDALDLIHGTPFTRRANIYAGDYADLKGSDVVIVAAGVPQKPGETRLQLLGRNARVMKEIARNVSKYAPDSIVIVVTNPVDVLTYFFLKESGMDPRKVFGSGTVLDTARLRTLIAQHCGFSPRSVHVYVIGEHGDSEVPVWSGAMIGGIPLQNMCQICQKCDSKILENFAEKTKRAAYEIIERKGATHYAIALAVADIVESIFFDEKRVLTLSVYLEDYLGVKDLCISVPVTLGKHGVERILELNLNEEELEAFRKSASILKNAINEITAEENKHQNTSG |
retinoid metabolic process | cytosol | alditol:NADP+ 1-oxidoreductase activity allyl-alcohol dehydrogenase activity glycerol dehydrogenase activity NADP-retinol dehydrogenase activity prostaglandin H2 endoperoxidase reductase activity retinal dehydrogenase activity | Bos taurus | Acetylation Cytoplasm Direct protein sequencing Lipid metabolism NADP Oxidoreductase Reference proteome | AHNIVLYTGA | AHNIVLYTGAKMPILGLGTWKSPPGKVTEAVKVAIDLGYRHIDCAHVYQNENEVGLALQAKLQEKVVKREDLFIVSKLWCTYHDKDLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKDFFPLDEDGNVIPSEKDFVDTWTAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPAVNQIECHPYLTQEKLIQYCNSKGIVVTAYSPLGSPDRPWAKPEDPSILEDPRIKAIADKYNKTTAQVLIRFPIQRNLIVIPKSVTPERIAENFQVFDFELDKEDMNTLLSYNRDWRACALVSCASHRDYPFHEEF | retinoid metabolic process cytosol alditol:NADP+ 1-oxidoreductase activity allyl-alcohol dehydrogenase activity glycerol dehydrogenase activity NADP-retinol dehydrogenase activity prostaglandin H2 endoperoxidase reductase activity retinal dehydrogenase activity Bos taurus Acetylation Cytoplasm Direct protein sequencing Lipid metabolism NADP Oxidoreductase Reference proteome AHNIVLYTGA AHNIVLYTGAKMPILGLGTWKSPPGKVTEAVKVAIDLGYRHIDCAHVYQNENEVGLALQAKLQEKVVKREDLFIVSKLWCTYHDKDLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKDFFPLDEDGNVIPSEKDFVDTWTAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPAVNQIECHPYLTQEKLIQYCNSKGIVVTAYSPLGSPDRPWAKPEDPSILEDPRIKAIADKYNKTTAQVLIRFPIQRNLIVIPKSVTPERIAENFQVFDFELDKEDMNTLLSYNRDWRACALVSCASHRDYPFHEEF |
animal organ regeneration fructose 2,6-bisphosphate metabolic process fructose metabolic process gluconeogenesis glycolytic process negative regulation of glycolytic process through fructose-6-phosphate response to cAMP response to glucagon response to glucocorticoid response to insulin response to starvation | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex; cytosol | 6-phosphofructo-2-kinase activity ATP binding fructose-2,6-bisphosphate 2-phosphatase activity fructose-6-phosphate binding identical protein binding kinase binding | Homo sapiens | 3D-structure Acetylation Alternative splicing ATP-binding Hydrolase Kinase Multifunctional enzyme Nucleotide-binding Phosphoprotein Reference proteome Transferase | MSPEMGELTQ | MSPEMGELTQTRLQKIWIPHSSGSSRLQRRRGSSIPQFTNSPTMVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNMEALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDPGIIAENIRQVKLGSPDYIDCDREKVLEDFLKRIECYEVNYQPLDEELDSHLSYIKIFDVGTRYMVNRVQDHIQSRTVYYLMNIHVTPRSIYLCRHGESELNIRGRIGGDSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTIQTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLKLTPVAYGCKVESIYLNVEAVNTHREKPENVDITREPEEALDTVPAHY | animal organ regeneration fructose 2,6-bisphosphate metabolic process fructose metabolic process gluconeogenesis glycolytic process negative regulation of glycolytic process through fructose-6-phosphate response to cAMP response to glucagon response to glucocorticoid response to insulin response to starvation 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex; cytosol 6-phosphofructo-2-kinase activity ATP binding fructose-2,6-bisphosphate 2-phosphatase activity fructose-6-phosphate binding identical protein binding kinase binding Homo sapiens 3D-structure Acetylation Alternative splicing ATP-binding Hydrolase Kinase Multifunctional enzyme Nucleotide-binding Phosphoprotein Reference proteome Transferase MSPEMGELTQ MSPEMGELTQTRLQKIWIPHSSGSSRLQRRRGSSIPQFTNSPTMVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNMEALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDPGIIAENIRQVKLGSPDYIDCDREKVLEDFLKRIECYEVNYQPLDEELDSHLSYIKIFDVGTRYMVNRVQDHIQSRTVYYLMNIHVTPRSIYLCRHGESELNIRGRIGGDSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTIQTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLKLTPVAYGCKVESIYLNVEAVNTHREKPENVDITREPEEALDTVPAHY |
lactate biosynthetic process from pyruvate lactate metabolic process NAD metabolic process pyruvate metabolic process | cytosol; membrane raft; mitochondrial inner membrane; mitochondrion; myelin sheath; oxidoreductase complex | identical protein binding kinase binding L-lactate dehydrogenase activity lactate dehydrogenase activity NAD binding | Mus musculus | Acetylation Cytoplasm Direct protein sequencing Membrane Mitochondrion Mitochondrion inner membrane NAD Oxidoreductase Phosphoprotein Reference proteome | MATLKEKLIA | MATLKEKLIASVADDEAAVPNNKITVVGVGQVGMACAISILGKSLADELALVDVLEDKLKGEMMDLQHGSLFLQTPKIVADKDYSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCTIIVVSNPVDILTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVHKMVVDSAYEVIKLKGYTNWAIGLSVADLIESMLKNLSRIHPVSTMVKGMYGIENEVFLSLPCILNARGLTSVINQKLKDDEVAQLRKSADTLWDIQKDLKDL | lactate biosynthetic process from pyruvate lactate metabolic process NAD metabolic process pyruvate metabolic process cytosol; membrane raft; mitochondrial inner membrane; mitochondrion; myelin sheath; oxidoreductase complex identical protein binding kinase binding L-lactate dehydrogenase activity lactate dehydrogenase activity NAD binding Mus musculus Acetylation Cytoplasm Direct protein sequencing Membrane Mitochondrion Mitochondrion inner membrane NAD Oxidoreductase Phosphoprotein Reference proteome MATLKEKLIA MATLKEKLIASVADDEAAVPNNKITVVGVGQVGMACAISILGKSLADELALVDVLEDKLKGEMMDLQHGSLFLQTPKIVADKDYSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCTIIVVSNPVDILTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVHKMVVDSAYEVIKLKGYTNWAIGLSVADLIESMLKNLSRIHPVSTMVKGMYGIENEVFLSLPCILNARGLTSVINQKLKDDEVAQLRKSADTLWDIQKDLKDL |
chlorophyll biosynthetic process photosynthesis | chloroplast; chloroplast stroma; cytosol; magnesium chelatase complex; plant-type cell wall | ATP binding ATP hydrolysis activity magnesium chelatase activity | Arabidopsis thaliana | Acetylation ATP-binding Chlorophyll biosynthesis Chloroplast Disulfide bond Ligase Nucleotide-binding Phosphoprotein Photosynthesis Plastid Reference proteome Transit peptide | MASLLGTSSS | MASLLGTSSSAIWASPSLSSPSSKPSSSPICFRPGKLFGSKLNAGIQIRPKKNRSRYHVSVMNVATEINSTEQVVGKFDSKKSARPVYPFAAIVGQDEMKLCLLLNVIDPKIGGVMIMGDRGTGKSTTVRSLVDLLPEINVVAGDPYNSDPIDPEFMGVEVRERVEKGEQVPVIATKINMVDLPLGATEDRVCGTIDIEKALTEGVKAFEPGLLAKANRGILYVDEVNLLDDHLVDVLLDSAASGWNTVEREGISISHPARFILIGSGNPEEGELRPQLLDRFGMHAQVGTVRDADLRVKIVEERARFDSNPKDFRDTYKTEQDKLQDQISTARANLSSVQIDRELKVKISRVCSELNVDGLRGDIVTNRAAKALAALKGKDRVTPDDVATVIPNCLRHRLRKDPLESIDSGVLVSEKFAEIFS | chlorophyll biosynthetic process photosynthesis chloroplast; chloroplast stroma; cytosol; magnesium chelatase complex; plant-type cell wall ATP binding ATP hydrolysis activity magnesium chelatase activity Arabidopsis thaliana Acetylation ATP-binding Chlorophyll biosynthesis Chloroplast Disulfide bond Ligase Nucleotide-binding Phosphoprotein Photosynthesis Plastid Reference proteome Transit peptide MASLLGTSSS MASLLGTSSSAIWASPSLSSPSSKPSSSPICFRPGKLFGSKLNAGIQIRPKKNRSRYHVSVMNVATEINSTEQVVGKFDSKKSARPVYPFAAIVGQDEMKLCLLLNVIDPKIGGVMIMGDRGTGKSTTVRSLVDLLPEINVVAGDPYNSDPIDPEFMGVEVRERVEKGEQVPVIATKINMVDLPLGATEDRVCGTIDIEKALTEGVKAFEPGLLAKANRGILYVDEVNLLDDHLVDVLLDSAASGWNTVEREGISISHPARFILIGSGNPEEGELRPQLLDRFGMHAQVGTVRDADLRVKIVEERARFDSNPKDFRDTYKTEQDKLQDQISTARANLSSVQIDRELKVKISRVCSELNVDGLRGDIVTNRAAKALAALKGKDRVTPDDVATVIPNCLRHRLRKDPLESIDSGVLVSEKFAEIFS |
ATP metabolic process endosomal lumen acidification Golgi lumen acidification intracellular calcium ion homeostasis pexophagy proteasome storage granule assembly proton transmembrane transport transmembrane transport vacuolar acidification | cytoplasm; cytoplasmic stress granule; fungal-type vacuole membrane; Golgi membrane; proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase, V1 domain; vacuole-mitochondrion membrane contact site | ATP binding proton-transporting ATPase activity, rotational mechanism | Saccharomyces cerevisiae | 3D-structure ATP-binding Direct protein sequencing Hydrogen ion transport Ion transport Isopeptide bond Membrane Nucleotide-binding Phosphoprotein Reference proteome Transport Ubl conjugation Vacuole | MVLSDKELFA | MVLSDKELFAINKKAVEQGFNVKPRLNYNTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTFITQGAYEDRTVFESLDQAWSLLRIYPKEMLNRISPKILDEFYDRARDDADEDEEDPDTRSSGKKKDASQEESLI | ATP metabolic process endosomal lumen acidification Golgi lumen acidification intracellular calcium ion homeostasis pexophagy proteasome storage granule assembly proton transmembrane transport transmembrane transport vacuolar acidification cytoplasm; cytoplasmic stress granule; fungal-type vacuole membrane; Golgi membrane; proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase, V1 domain; vacuole-mitochondrion membrane contact site ATP binding proton-transporting ATPase activity, rotational mechanism Saccharomyces cerevisiae 3D-structure ATP-binding Direct protein sequencing Hydrogen ion transport Ion transport Isopeptide bond Membrane Nucleotide-binding Phosphoprotein Reference proteome Transport Ubl conjugation Vacuole MVLSDKELFA MVLSDKELFAINKKAVEQGFNVKPRLNYNTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTFITQGAYEDRTVFESLDQAWSLLRIYPKEMLNRISPKILDEFYDRARDDADEDEEDPDTRSSGKKKDASQEESLI |
Notch signaling pathway positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II radial glial cell differentiation regulation of apoptotic process | cytoplasm; nucleus; transcription regulator complex | DNA-binding transcription factor activity, RNA polymerase II-specific sequence-specific DNA binding | Xenopus laevis | Activator Alternative splicing Cytoplasm Developmental protein DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation | MKLHSSSKIQ | MKLHSSSKIQNHAWLSDARMNNPSETSKSPESGDGNTGTQTNGLDFQKQAVPIGAITSAQAQALLGHLHQVQLAGTSLQAAAHSLNVQTKFKEEPGEPMQVVQPSQQPSLQAAIPQTQLMVAGGQIAGLTLTPAQQQMLLQQAQAQLLAAAVQHSASQQHNAAGATISASAATPMTQIPLSQPIQIAQDLQQLQQLQQQNLNLQQYVLVHPTTNLQSAQFIISQTPQGQQGLLQAQNLLTQLPQQSQANLLQSQPSITLTSQPATPTRTIAATPVQQLPQSQTTPKRIDTPSLEEPSDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAENITSDSTLTNQSVLNSPGHGMEGLNRRRKKRTSIETNIRVALEKSFLENQKPTSEEITMIADQLNMEKEVIRVWFCNRRQKEKRINPPSSGGSSSSPIKSLFSSPNPLVASTPSLVTSSPATTLTVNPVLPLTSAAAITSFHIPGTTGTSSANTATVISTAPPVSSVLTSPSLSSSPSATAASSEASTAGETSTTQTTSTPMTSSLNTGQVMVTASGIHTAAATALQGAAQLPTNASLAAMAAAAGLNPGLMAPSQFAAGGALFSLNPGALGSALSPALMSNSTLATIQALASSGSLPITSLDAAGNLVFANAGGTPNIVTAPLFLNPQNLSLFTSNPVSLISAASAGATGPITSLHATTSSIDSIQNALFTMASASGAASTTTSASKAQ | Notch signaling pathway positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II radial glial cell differentiation regulation of apoptotic process cytoplasm; nucleus; transcription regulator complex DNA-binding transcription factor activity, RNA polymerase II-specific sequence-specific DNA binding Xenopus laevis Activator Alternative splicing Cytoplasm Developmental protein DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation MKLHSSSKIQ MKLHSSSKIQNHAWLSDARMNNPSETSKSPESGDGNTGTQTNGLDFQKQAVPIGAITSAQAQALLGHLHQVQLAGTSLQAAAHSLNVQTKFKEEPGEPMQVVQPSQQPSLQAAIPQTQLMVAGGQIAGLTLTPAQQQMLLQQAQAQLLAAAVQHSASQQHNAAGATISASAATPMTQIPLSQPIQIAQDLQQLQQLQQQNLNLQQYVLVHPTTNLQSAQFIISQTPQGQQGLLQAQNLLTQLPQQSQANLLQSQPSITLTSQPATPTRTIAATPVQQLPQSQTTPKRIDTPSLEEPSDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAENITSDSTLTNQSVLNSPGHGMEGLNRRRKKRTSIETNIRVALEKSFLENQKPTSEEITMIADQLNMEKEVIRVWFCNRRQKEKRINPPSSGGSSSSPIKSLFSSPNPLVASTPSLVTSSPATTLTVNPVLPLTSAAAITSFHIPGTTGTSSANTATVISTAPPVSSVLTSPSLSSSPSATAASSEASTAGETSTTQTTSTPMTSSLNTGQVMVTASGIHTAAATALQGAAQLPTNASLAAMAAAAGLNPGLMAPSQFAAGGALFSLNPGALGSALSPALMSNSTLATIQALASSGSLPITSLDAAGNLVFANAGGTPNIVTAPLFLNPQNLSLFTSNPVSLISAASAGATGPITSLHATTSSIDSIQNALFTMASASGAASTTTSASKAQ |
apoptotic signaling pathway cell surface receptor signaling pathway cellular defense response chemotaxis defense response to bacterium establishment or maintenance of cell polarity immune response leukocyte tethering or rolling negative regulation of cell adhesion negative regulation of T cell proliferation negative regulation of type IV hypersensitivity negative thymic T cell selection positive regulation of protein phosphorylation positive regulation of T cell migration positive regulation of T cell proliferation positive regulation of tumor necrosis factor production regulation of defense response to virus regulation of immune response regulation of T cell migration response to protozoan signal transduction T cell costimulation T cell proliferation T-helper 1 cell lineage commitment | basement membrane; cell surface; external side of plasma membrane; extracellular exosome; extracellular space; membrane; microvillus; plasma membrane; PML body; uropod | heat shock protein binding Hsp70 protein binding transmembrane signaling receptor activity | Homo sapiens | Cell projection Direct protein sequencing Glycoprotein Membrane Nucleus Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix Ubl conjugation | MATLLLLLGV | MATLLLLLGVLVVSPDALGSTTAVQTPTSGEPLVSTSEPLSSKMYTTSITSDPKADSTGDQTSALPPSTSINEGSPLWTSIGASTGSPLPEPTTYQEVSIKMSSVPQETPHATSHPAVPITANSLGSHTVTGGTITTNSPETSSRTSGAPVTTAASSLETSRGTSGPPLTMATVSLETSKGTSGPPVTMATDSLETSTGTTGPPVTMTTGSLEPSSGASGPQVSSVKLSTMMSPTTSTNASTVPFRNPDENSRGMLPVAVLVALLAVIVLVALLLLWRRRQKRRTGALVLSRGGKRNGVVDAWAGPAQVPEEGAVTVTVGGSGGDKGSGFPDGEGSSRRPTLTTFFGRRKSRQGSLAMEELKSGSGPSLKGEEEPLVASEDGAVDAPAPDEPEGGDGAAP | apoptotic signaling pathway cell surface receptor signaling pathway cellular defense response chemotaxis defense response to bacterium establishment or maintenance of cell polarity immune response leukocyte tethering or rolling negative regulation of cell adhesion negative regulation of T cell proliferation negative regulation of type IV hypersensitivity negative thymic T cell selection positive regulation of protein phosphorylation positive regulation of T cell migration positive regulation of T cell proliferation positive regulation of tumor necrosis factor production regulation of defense response to virus regulation of immune response regulation of T cell migration response to protozoan signal transduction T cell costimulation T cell proliferation T-helper 1 cell lineage commitment basement membrane; cell surface; external side of plasma membrane; extracellular exosome; extracellular space; membrane; microvillus; plasma membrane; PML body; uropod heat shock protein binding Hsp70 protein binding transmembrane signaling receptor activity Homo sapiens Cell projection Direct protein sequencing Glycoprotein Membrane Nucleus Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix Ubl conjugation MATLLLLLGV MATLLLLLGVLVVSPDALGSTTAVQTPTSGEPLVSTSEPLSSKMYTTSITSDPKADSTGDQTSALPPSTSINEGSPLWTSIGASTGSPLPEPTTYQEVSIKMSSVPQETPHATSHPAVPITANSLGSHTVTGGTITTNSPETSSRTSGAPVTTAASSLETSRGTSGPPLTMATVSLETSKGTSGPPVTMATDSLETSTGTTGPPVTMTTGSLEPSSGASGPQVSSVKLSTMMSPTTSTNASTVPFRNPDENSRGMLPVAVLVALLAVIVLVALLLLWRRRQKRRTGALVLSRGGKRNGVVDAWAGPAQVPEEGAVTVTVGGSGGDKGSGFPDGEGSSRRPTLTTFFGRRKSRQGSLAMEELKSGSGPSLKGEEEPLVASEDGAVDAPAPDEPEGGDGAAP |
allantoin biosynthetic process purine nucleobase catabolic process urate catabolic process | peroxisome | urate oxidase activity | Drosophila melanogaster | Oxidoreductase Peroxisome Purine metabolism Reference proteome | MFATPLRQPA | MFATPLRQPAAANHQTPKNSAGMDEHGKPYQYEITDHGYGKDAVKVLHVSRNGPVHAIQEFEVGTHLKLYSKKDYYQGNNSDIVATDSQKNTVYLLAKKHGIESPEKFALLLARHFINKYSHVEEAHVHVEAYPWQRVCQEETRTNVNGKCENGVQGNCDFSSIDNRSLHNHAFIFTPTALHYCDVVIRRTDPKQTVITGIKGLRVLKTTQSSFVNFVNDEFRSLPDQYDRIFSTVVDCSWEYSDTENLDFLRAWQTVKNIIIRNFAGDPQVGVSSPSVQHTLYLSERQVLDVLPQVSVISMTMPNKHYFNFDTKPFQKIAPGDNNEVFIPVDKPHGTIYAQLARKNINSHL | allantoin biosynthetic process purine nucleobase catabolic process urate catabolic process peroxisome urate oxidase activity Drosophila melanogaster Oxidoreductase Peroxisome Purine metabolism Reference proteome MFATPLRQPA MFATPLRQPAAANHQTPKNSAGMDEHGKPYQYEITDHGYGKDAVKVLHVSRNGPVHAIQEFEVGTHLKLYSKKDYYQGNNSDIVATDSQKNTVYLLAKKHGIESPEKFALLLARHFINKYSHVEEAHVHVEAYPWQRVCQEETRTNVNGKCENGVQGNCDFSSIDNRSLHNHAFIFTPTALHYCDVVIRRTDPKQTVITGIKGLRVLKTTQSSFVNFVNDEFRSLPDQYDRIFSTVVDCSWEYSDTENLDFLRAWQTVKNIIIRNFAGDPQVGVSSPSVQHTLYLSERQVLDVLPQVSVISMTMPNKHYFNFDTKPFQKIAPGDNNEVFIPVDKPHGTIYAQLARKNINSHL |
positive regulation of blood pressure positive regulation of flagellated sperm motility positive regulation of heart rate positive regulation of uterine smooth muscle contraction regulation of dopamine metabolic process regulation of feeding behavior response to cocaine response to estradiol | dendrite membrane; neuronal cell body membrane; plasma membrane; sperm midpiece | tachykinin receptor activity | Rattus norvegicus | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MASVPRGENW | MASVPRGENWTDGTVEVGTHTGNLSSALGVTEWLALQAGNFSSALGLPATTQAPSQVRANLTNQFVQPSWRIALWSLAYGLVVAVAVFGNLIVIWIILAHKRMRTVTNYFLVNLAFSDASVAAFNTLINFIYGLHSEWYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKPRLSATATKIVIGSIWILAFLLAFPQCLYSKIKVMPGRTLCYVQWPEGPKQHFTYHIIVIILVYCFPLLIMGVTYTIVGITLWGGEIPGDTCDKYHEQLKAKRKVVKMMIIVVVTFAICWLPYHVYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTMYNPIIYCCLNKRFRAGFKRAFRWCPFIQVSSYDELELKTTRFHPTRQSSLYTVSRMESVTVLFDPNDGDPTKSSRKKRAVPRDPSANGCSHRGSKSASTTSSFISSPYTSVDEYS | positive regulation of blood pressure positive regulation of flagellated sperm motility positive regulation of heart rate positive regulation of uterine smooth muscle contraction regulation of dopamine metabolic process regulation of feeding behavior response to cocaine response to estradiol dendrite membrane; neuronal cell body membrane; plasma membrane; sperm midpiece tachykinin receptor activity Rattus norvegicus Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix MASVPRGENW MASVPRGENWTDGTVEVGTHTGNLSSALGVTEWLALQAGNFSSALGLPATTQAPSQVRANLTNQFVQPSWRIALWSLAYGLVVAVAVFGNLIVIWIILAHKRMRTVTNYFLVNLAFSDASVAAFNTLINFIYGLHSEWYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKPRLSATATKIVIGSIWILAFLLAFPQCLYSKIKVMPGRTLCYVQWPEGPKQHFTYHIIVIILVYCFPLLIMGVTYTIVGITLWGGEIPGDTCDKYHEQLKAKRKVVKMMIIVVVTFAICWLPYHVYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTMYNPIIYCCLNKRFRAGFKRAFRWCPFIQVSSYDELELKTTRFHPTRQSSLYTVSRMESVTVLFDPNDGDPTKSSRKKRAVPRDPSANGCSHRGSKSASTTSSFISSPYTSVDEYS |
plastid translation | chloroplast; chloroplast envelope; chloroplast stroma; chloroplast thylakoid; mitochondrion; plastid small ribosomal subunit | mRNA binding rRNA binding structural constituent of ribosome | Arabidopsis thaliana | Chloroplast Plastid Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding rRNA-binding Transit peptide | MITSSLTSSL | MITSSLTSSLQALKLSSPFAHGSTPLSSLSKPNSFPNHRMPALVPVIRAMKTMQGRVVCATSDKTVAVEVVRLAPHPKYKRRVRMKKKYQAHDPDNQFKVGDVVRLEKSRPISKTKSFVALPVIARAARKAEAGGDELLGLPLESQQPA | plastid translation chloroplast; chloroplast envelope; chloroplast stroma; chloroplast thylakoid; mitochondrion; plastid small ribosomal subunit mRNA binding rRNA binding structural constituent of ribosome Arabidopsis thaliana Chloroplast Plastid Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding rRNA-binding Transit peptide MITSSLTSSL MITSSLTSSLQALKLSSPFAHGSTPLSSLSKPNSFPNHRMPALVPVIRAMKTMQGRVVCATSDKTVAVEVVRLAPHPKYKRRVRMKKKYQAHDPDNQFKVGDVVRLEKSRPISKTKSFVALPVIARAARKAEAGGDELLGLPLESQQPA |
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity | early endosome membrane; ER to Golgi transport vesicle membrane; external side of plasma membrane; extracellular space; lumenal side of endoplasmic reticulum membrane; MHC class I protein complex; phagocytic vesicle membrane; recycling endosome membrane | peptide antigen binding signaling receptor binding | Pan troglodytes | Disulfide bond Glycoprotein Immunity Membrane MHC I Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix | MAVMPPRTLL | MAVMPPRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDEETRSAKAHSQTDRVDLGTLRGYYNQSEDGSHTIQIMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHAAEQRRAYLEGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQAASSDSAQGSDVSLTACKV | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity early endosome membrane; ER to Golgi transport vesicle membrane; external side of plasma membrane; extracellular space; lumenal side of endoplasmic reticulum membrane; MHC class I protein complex; phagocytic vesicle membrane; recycling endosome membrane peptide antigen binding signaling receptor binding Pan troglodytes Disulfide bond Glycoprotein Immunity Membrane MHC I Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix MAVMPPRTLL MAVMPPRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDEETRSAKAHSQTDRVDLGTLRGYYNQSEDGSHTIQIMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHAAEQRRAYLEGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQAASSDSAQGSDVSLTACKV |
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity | early endosome membrane; ER to Golgi transport vesicle membrane; external side of plasma membrane; extracellular space; lumenal side of endoplasmic reticulum membrane; MHC class I protein complex; phagocytic vesicle membrane; recycling endosome membrane | peptide antigen binding signaling receptor binding | Pan troglodytes | Disulfide bond Glycoprotein Immunity Membrane MHC I Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix | MQVTAPRTVL | MQVTAPRTVLLLLSAALALTETWAGSHSMKYFYTAVSRPGRGEPRFISVGYVDDTQFVWFDSDAASPREEPRAPWIEQEGPEYWDRETQISKTNAQTYRESLRNLRGYYNQSEAGSHIIQRMYGCDMGPDGRLLRGYEQYAYDGKDYIALNQDLSSWTAADTAAQITQRKWEAARWAEQLRAYLEGTCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQSTIPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSYSQAASSDSAQGSDVSLTA | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity early endosome membrane; ER to Golgi transport vesicle membrane; external side of plasma membrane; extracellular space; lumenal side of endoplasmic reticulum membrane; MHC class I protein complex; phagocytic vesicle membrane; recycling endosome membrane peptide antigen binding signaling receptor binding Pan troglodytes Disulfide bond Glycoprotein Immunity Membrane MHC I Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix MQVTAPRTVL MQVTAPRTVLLLLSAALALTETWAGSHSMKYFYTAVSRPGRGEPRFISVGYVDDTQFVWFDSDAASPREEPRAPWIEQEGPEYWDRETQISKTNAQTYRESLRNLRGYYNQSEAGSHIIQRMYGCDMGPDGRLLRGYEQYAYDGKDYIALNQDLSSWTAADTAAQITQRKWEAARWAEQLRAYLEGTCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQSTIPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSYSQAASSDSAQGSDVSLTA |
butyrate catabolic process fatty acid beta-oxidation fatty acid beta-oxidation using acyl-CoA dehydrogenase | centrosome; mitochondrial matrix; mitochondrion; nucleoplasm; nucleus | acyl-CoA dehydrogenase activity butyryl-CoA dehydrogenase activity flavin adenine dinucleotide binding | Homo sapiens | 3D-structure Acetylation Direct protein sequencing Disease variant FAD Fatty acid metabolism Flavoprotein Lipid metabolism Mitochondrion Oxidoreductase Phosphoprotein Reference proteome Transit peptide | MAAALLARAS | MAAALLARASGPARRALCPRAWRQLHTIYQSVELPETHQMLLQTCRDFAEKELFPIAAQVDKEHLFPAAQVKKMGGLGLLAMDVPEELGGAGLDYLAYAIAMEEISRGCASTGVIMSVNNSLYLGPILKFGSKEQKQAWVTPFTSGDKIGCFALSEPGNGSDAGAASTTARAEGDSWVLNGTKAWITNAWEASAAVVFASTDRALQNKGISAFLVPMPTPGLTLGKKEDKLGIRGSSTANLIFEDCRIPKDSILGEPGMGFKIAMQTLDMGRIGIASQALGIAQTALDCAVNYAENRMAFGAPLTKLQVIQFKLADMALALESARLLTWRAAMLKDNKKPFIKEAAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERHYRDARITEIYEGTSEIQRLVIAGHLLRSYRS | butyrate catabolic process fatty acid beta-oxidation fatty acid beta-oxidation using acyl-CoA dehydrogenase centrosome; mitochondrial matrix; mitochondrion; nucleoplasm; nucleus acyl-CoA dehydrogenase activity butyryl-CoA dehydrogenase activity flavin adenine dinucleotide binding Homo sapiens 3D-structure Acetylation Direct protein sequencing Disease variant FAD Fatty acid metabolism Flavoprotein Lipid metabolism Mitochondrion Oxidoreductase Phosphoprotein Reference proteome Transit peptide MAAALLARAS MAAALLARASGPARRALCPRAWRQLHTIYQSVELPETHQMLLQTCRDFAEKELFPIAAQVDKEHLFPAAQVKKMGGLGLLAMDVPEELGGAGLDYLAYAIAMEEISRGCASTGVIMSVNNSLYLGPILKFGSKEQKQAWVTPFTSGDKIGCFALSEPGNGSDAGAASTTARAEGDSWVLNGTKAWITNAWEASAAVVFASTDRALQNKGISAFLVPMPTPGLTLGKKEDKLGIRGSSTANLIFEDCRIPKDSILGEPGMGFKIAMQTLDMGRIGIASQALGIAQTALDCAVNYAENRMAFGAPLTKLQVIQFKLADMALALESARLLTWRAAMLKDNKKPFIKEAAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERHYRDARITEIYEGTSEIQRLVIAGHLLRSYRS |
antibacterial humoral response copulation innate immune response | extracellular space | serine-type endopeptidase inhibitor activity | Sus scrofa | Direct protein sequencing Disulfide bond Pyrrolidone carboxylic acid Reference proteome Repeat Signal | MRSRSFLVLV | MRSRSFLVLVAVFLICETLVAQRLDRIRGPKGQGQDPVEGQDQDEGPGPVKVEILDIGQDPVKGQDPVKGQDPVKGQDPVKGQDLVKSQDPVKAELPDIGQDVVKGHEPVEGQDPVNAQLPDKVQDPVKAQPAVPGRFLLSKRGHCPRILFRCPLSNPSNKCWRDYDCPGVKKCCEGFCGKDCLYPK | antibacterial humoral response copulation innate immune response extracellular space serine-type endopeptidase inhibitor activity Sus scrofa Direct protein sequencing Disulfide bond Pyrrolidone carboxylic acid Reference proteome Repeat Signal MRSRSFLVLV MRSRSFLVLVAVFLICETLVAQRLDRIRGPKGQGQDPVEGQDQDEGPGPVKVEILDIGQDPVKGQDPVKGQDPVKGQDPVKGQDLVKSQDPVKAELPDIGQDVVKGHEPVEGQDPVNAQLPDKVQDPVKAQPAVPGRFLLSKRGHCPRILFRCPLSNPSNKCWRDYDCPGVKKCCEGFCGKDCLYPK |
antigen processing and presentation of exogenous peptide antigen via MHC class II protein autoprocessing proteolysis | endosome | aspartic-type endopeptidase activity identical protein binding peptidase activity | Rattus norvegicus | Alternative splicing Aspartyl protease Autocatalytic cleavage Direct protein sequencing Disulfide bond Endosome Glycoprotein Hydrolase Protease Reference proteome Signal Zymogen | MKPLFVLLLL | MKPLFVLLLLLLLLDLAQAQGVLHRVPLRRHQSLRKKLRAQGQLSDFWRSHNLDMIEFSESCNVDKGINEPLINYLDMEYFGTVSIGSPSQNFTVIFDTGSSNLWVPSVYCTSPACKAHPVFHPSQSSTYMEVGNHFSIQYGTGSLTGIIGADQVSVEGLTVEGQQFGESVKEPGQTFVNAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVALPMFSVYLSSDPQGGSGSELTFGGYDPSHFSGSLNWIPVTKQGYWQIALDGIQVGDTVMFCSEGCQAIVDTGTSLITGPPKKIKQLQEAIGATPMDGEYAVDCATLNMMPNVTFLINGVSYTLSPTAYILPDLVDGMQFCGSGFQGLDIQPPAGPLWILGDVFIRKFYSVFDRGNNQVGLAPAVP | antigen processing and presentation of exogenous peptide antigen via MHC class II protein autoprocessing proteolysis endosome aspartic-type endopeptidase activity identical protein binding peptidase activity Rattus norvegicus Alternative splicing Aspartyl protease Autocatalytic cleavage Direct protein sequencing Disulfide bond Endosome Glycoprotein Hydrolase Protease Reference proteome Signal Zymogen MKPLFVLLLL MKPLFVLLLLLLLLDLAQAQGVLHRVPLRRHQSLRKKLRAQGQLSDFWRSHNLDMIEFSESCNVDKGINEPLINYLDMEYFGTVSIGSPSQNFTVIFDTGSSNLWVPSVYCTSPACKAHPVFHPSQSSTYMEVGNHFSIQYGTGSLTGIIGADQVSVEGLTVEGQQFGESVKEPGQTFVNAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVALPMFSVYLSSDPQGGSGSELTFGGYDPSHFSGSLNWIPVTKQGYWQIALDGIQVGDTVMFCSEGCQAIVDTGTSLITGPPKKIKQLQEAIGATPMDGEYAVDCATLNMMPNVTFLINGVSYTLSPTAYILPDLVDGMQFCGSGFQGLDIQPPAGPLWILGDVFIRKFYSVFDRGNNQVGLAPAVP |
cellular response to estradiol stimulus glucocorticoid biosynthetic process glucocorticoid catabolic process lung development mineralocorticoid metabolic process regulation of pentose-phosphate shunt response to nutrient levels steroid catabolic process | apical part of cell; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; nuclear membrane | 11-beta-hydroxysteroid dehydrogenase (NADP+) activity 7-beta-hydroxysteroid dehydrogenase (NADP+) activity cortisol dehydrogenase activity NADP binding protein homodimerization activity steroid binding | Rattus norvegicus | Alternative promoter usage Direct protein sequencing Endoplasmic reticulum Glycoprotein Lipid metabolism Membrane NADP Oxidoreductase Reference proteome Signal-anchor Steroid metabolism Transmembrane Transmembrane helix | MKKYLLPVLV | MKKYLLPVLVLCLGYYYSTNEEFRPEMLQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLELGAASAHYIAGTMEDMAFAERFVVEAGKLLGGLDMLILNHITQTTMSLFHDDIHSVRRSMEVNFLSYVVLSTAALPMLKQSNGSIAIISSMAGKMTQPLIASYSASKFALDGFFSTIRKEHLMTKVNVSITLCVLGFIDTETALKETSGIILSQAAPKEECALEIIKGTVLRKDEVYYDKSSWTPLLLGNPGRRIMEFLSLRSYNRDLFVSN | cellular response to estradiol stimulus glucocorticoid biosynthetic process glucocorticoid catabolic process lung development mineralocorticoid metabolic process regulation of pentose-phosphate shunt response to nutrient levels steroid catabolic process apical part of cell; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; nuclear membrane 11-beta-hydroxysteroid dehydrogenase (NADP+) activity 7-beta-hydroxysteroid dehydrogenase (NADP+) activity cortisol dehydrogenase activity NADP binding protein homodimerization activity steroid binding Rattus norvegicus Alternative promoter usage Direct protein sequencing Endoplasmic reticulum Glycoprotein Lipid metabolism Membrane NADP Oxidoreductase Reference proteome Signal-anchor Steroid metabolism Transmembrane Transmembrane helix MKKYLLPVLV MKKYLLPVLVLCLGYYYSTNEEFRPEMLQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLELGAASAHYIAGTMEDMAFAERFVVEAGKLLGGLDMLILNHITQTTMSLFHDDIHSVRRSMEVNFLSYVVLSTAALPMLKQSNGSIAIISSMAGKMTQPLIASYSASKFALDGFFSTIRKEHLMTKVNVSITLCVLGFIDTETALKETSGIILSQAAPKEECALEIIKGTVLRKDEVYYDKSSWTPLLLGNPGRRIMEFLSLRSYNRDLFVSN |
intestinal cholesterol absorption lipid catabolic process lipid metabolic process positive regulation of triglyceride lipase activity | extracellular region; extracellular space | all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity lipase activity metal ion binding triglyceride lipase activity | Homo sapiens | 3D-structure Calcium Disease variant Disulfide bond Glycoprotein Hydrolase Lipid degradation Lipid metabolism Metal-binding Reference proteome Secreted Signal | MLPLWTLSLL | MLPLWTLSLLLGAVAGKEVCYERLGCFSDDSPWSGITERPLHILPWSPKDVNTRFLLYTNENPNNFQEVAADSSSISGSNFKTNRKTRFIIHGFIDKGEENWLANVCKNLFKVESVNCICVDWKGGSRTGYTQASQNIRIVGAEVAYFVEFLQSAFGYSPSNVHVIGHSLGAHAAGEAGRRTNGTIGRITGLDPAEPCFQGTPELVRLDPSDAKFVDVIHTDGAPIVPNLGFGMSQVVGHLDFFPNGGVEMPGCKKNILSQIVDIDGIWEGTRDFAACNHLRSYKYYTDSIVNPDGFAGFPCASYNVFTANKCFPCPSGGCPQMGHYADRYPGKTNDVGQKFYLDTGDASNFARWRYKVSVTLSGKKVTGHILVSLFGNKGNSKQYEIFKGTLKPDSTHSNEFDSDVDVGDLQMVKFIWYNNVINPTLPRVGASKIIVETNVGKQFNFCSPETVREEVLLTLTPC | intestinal cholesterol absorption lipid catabolic process lipid metabolic process positive regulation of triglyceride lipase activity extracellular region; extracellular space all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity lipase activity metal ion binding triglyceride lipase activity Homo sapiens 3D-structure Calcium Disease variant Disulfide bond Glycoprotein Hydrolase Lipid degradation Lipid metabolism Metal-binding Reference proteome Secreted Signal MLPLWTLSLL MLPLWTLSLLLGAVAGKEVCYERLGCFSDDSPWSGITERPLHILPWSPKDVNTRFLLYTNENPNNFQEVAADSSSISGSNFKTNRKTRFIIHGFIDKGEENWLANVCKNLFKVESVNCICVDWKGGSRTGYTQASQNIRIVGAEVAYFVEFLQSAFGYSPSNVHVIGHSLGAHAAGEAGRRTNGTIGRITGLDPAEPCFQGTPELVRLDPSDAKFVDVIHTDGAPIVPNLGFGMSQVVGHLDFFPNGGVEMPGCKKNILSQIVDIDGIWEGTRDFAACNHLRSYKYYTDSIVNPDGFAGFPCASYNVFTANKCFPCPSGGCPQMGHYADRYPGKTNDVGQKFYLDTGDASNFARWRYKVSVTLSGKKVTGHILVSLFGNKGNSKQYEIFKGTLKPDSTHSNEFDSDVDVGDLQMVKFIWYNNVINPTLPRVGASKIIVETNVGKQFNFCSPETVREEVLLTLTPC |
apoptotic DNA fragmentation canonical NF-kappaB signal transduction inflammatory response innate immune response non-canonical NF-kappaB signal transduction positive regulation of transcription by RNA polymerase II response to cytokine | cytoplasm; nucleus | DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding | Gallus gallus | 3D-structure DNA-binding Nucleus Phosphoprotein Proto-oncogene Reference proteome | MAGISEPYIE | MAGISEPYIEIFEQPRQRGMRFRYKCEGRSAGSIPGEHSTDNNKTFPSIQILNYFGKVKIRTTLVTKNEPYKPHPHDLVGKDCRDGYYEAEFGPERRVLSFQNLGIQCVKKKDLKESISLRISKKINPFNVPEEQLHNIDEYDLNVVRLCFQAFLPDEHGNYTLALPPLISNPIYDNRAPNTAELRICRVNKNCGSVKGGDEIFILCDKVQKDDIEVRFVLDNWEAKGSFSQADVHRQVAIVFRTPPFLRDITEPITVKMQLRRPSDQEVSEPMDFRYLPDEKDPYGNKAKRQRSTLAWQKLIQDCGSAVTERPKAAPIPTVNPEGKLIKKEPNMFSPTLMLPGLGTLTSSSQMYPPCSQMPHQPAQLGPGKQDTLPSCWQQLFSSSPSASSLLSMHPHNSFTAEVPQPGAQGSSSLPAFHDNPLNWPDEKDSSFYRNFGSTNGMGAAMVSAADMQSASSNSIVHATHQASATAASIVNMETNDMNCTSLNFEKYTQVLNVSNHRQQLHQAPAACPPVAAPGSTPFSSQPNLADTAVYNSFLDQEVISDSRLSTNPLQNHQNSLTLTDNQFYDTDGVHTDELYQSFQLDTNILQSYNH | apoptotic DNA fragmentation canonical NF-kappaB signal transduction inflammatory response innate immune response non-canonical NF-kappaB signal transduction positive regulation of transcription by RNA polymerase II response to cytokine cytoplasm; nucleus DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding Gallus gallus 3D-structure DNA-binding Nucleus Phosphoprotein Proto-oncogene Reference proteome MAGISEPYIE MAGISEPYIEIFEQPRQRGMRFRYKCEGRSAGSIPGEHSTDNNKTFPSIQILNYFGKVKIRTTLVTKNEPYKPHPHDLVGKDCRDGYYEAEFGPERRVLSFQNLGIQCVKKKDLKESISLRISKKINPFNVPEEQLHNIDEYDLNVVRLCFQAFLPDEHGNYTLALPPLISNPIYDNRAPNTAELRICRVNKNCGSVKGGDEIFILCDKVQKDDIEVRFVLDNWEAKGSFSQADVHRQVAIVFRTPPFLRDITEPITVKMQLRRPSDQEVSEPMDFRYLPDEKDPYGNKAKRQRSTLAWQKLIQDCGSAVTERPKAAPIPTVNPEGKLIKKEPNMFSPTLMLPGLGTLTSSSQMYPPCSQMPHQPAQLGPGKQDTLPSCWQQLFSSSPSASSLLSMHPHNSFTAEVPQPGAQGSSSLPAFHDNPLNWPDEKDSSFYRNFGSTNGMGAAMVSAADMQSASSNSIVHATHQASATAASIVNMETNDMNCTSLNFEKYTQVLNVSNHRQQLHQAPAACPPVAAPGSTPFSSQPNLADTAVYNSFLDQEVISDSRLSTNPLQNHQNSLTLTDNQFYDTDGVHTDELYQSFQLDTNILQSYNH |
brain development brain segmentation dendrite morphogenesis motor neuron axon guidance peripheral nervous system development positive regulation of antimicrobial peptide biosynthetic process positive regulation of transcription by RNA polymerase II regulation of dendrite morphogenesis regulation of transcription by RNA polymerase II | nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding | Drosophila melanogaster | Activator DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation | MAATSYMTPP | MAATSYMTPPSGDLDMALGGGGYHTSSPRSAADAGEMKYMQHHHHHHAAAAAAAHHQLPSSPSPNGQGNGGGLGLGSGSGLGSWSALHPDPWMQTHHTHHLPAAAAVASAADTVKQEMSHLSQQTRIQQGMASPHAAWHAPHAGHYAPTGGSPLQYHHAMNGMLHHPAHAVAAAHHQSVAPLHHTLRGESPQLHIHHHMGGGDRDAISGGEEDTPTSDDLEAFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLQKWLEEADSTTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALEQHFHKQPKPSAQEITSLADSLQLEKEVVRVWFCNRRQKEKRMTPPNTLGGDMMDGMPPGHMHHGGYHPHHDMHGSPMGTHSHSHSPPMLSPQNMQSSAVAAHQLAAH | brain development brain segmentation dendrite morphogenesis motor neuron axon guidance peripheral nervous system development positive regulation of antimicrobial peptide biosynthetic process positive regulation of transcription by RNA polymerase II regulation of dendrite morphogenesis regulation of transcription by RNA polymerase II nucleus DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding Drosophila melanogaster Activator DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation MAATSYMTPP MAATSYMTPPSGDLDMALGGGGYHTSSPRSAADAGEMKYMQHHHHHHAAAAAAAHHQLPSSPSPNGQGNGGGLGLGSGSGLGSWSALHPDPWMQTHHTHHLPAAAAVASAADTVKQEMSHLSQQTRIQQGMASPHAAWHAPHAGHYAPTGGSPLQYHHAMNGMLHHPAHAVAAAHHQSVAPLHHTLRGESPQLHIHHHMGGGDRDAISGGEEDTPTSDDLEAFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLQKWLEEADSTTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALEQHFHKQPKPSAQEITSLADSLQLEKEVVRVWFCNRRQKEKRMTPPNTLGGDMMDGMPPGHMHHGGYHPHHDMHGSPMGTHSHSHSPPMLSPQNMQSSAVAAHQLAAH |
malate metabolic process pyruvate metabolic process | chloroplast | malate dehydrogenase (decarboxylating) (NADP+) activity metal ion binding NAD binding oxaloacetate decarboxylase activity | Zea mays | 3D-structure Chloroplast Metal-binding NAD NADP Oxidoreductase Plastid Reference proteome Transit peptide | MLSTRTAAVA | MLSTRTAAVAASASPASPWKLGGRSEGGASCDGCRTYRNTLRRRAAPAKVRALPPRRVDAVAMVSNAETETEKEQEEAAAASEELPVMPWATSVASGYTLLRDPHHNKGLAFTEEERDGHYLRGLLPPAVLSQELQIKKFMNTLRQYQTPLQRYIAMMNLQETDERLFYKLLIDNVVELLPFVYTPTVGEACQKYGSIFGRPQGLYVSLKDKGKVLEVLRNWPHRNIQVICVTDGERILGLGDLGCQGMGIPVGKLALYTALGGVDPSVCLPITIDVGTNNEFLLNDEFYIGLRQKRATGEEYDELIEEFMSAVKQFYGEKVLIQFEDFANHNAFDLLEKYSKSHLVFNDDIQGTASVVLAGLLAALKMVGGTLAEQTYLFLGAGEAGTGIAELIALEISKQTNAPIEECRKKVWLVDSKGLIVDSRKGSLQPFKKPWAHEHEPLKTLYDAVQSIKPTVLIGTSGVGRTFTKEIIEAMSSFNERPIIFSLSNPTSHSECTAEQAYTWSQGRSIFASGSPFAPVEYEGKTFVPGQSNNAYIFPGLGLGLVISGAVRVHEDMLLAASKALADQATQDNFEKGSIFPPFTSIRKISAHIAAAVAGKAYELGLATRLPPPSDLVKYAENCMYTPVYRNYR | malate metabolic process pyruvate metabolic process chloroplast malate dehydrogenase (decarboxylating) (NADP+) activity metal ion binding NAD binding oxaloacetate decarboxylase activity Zea mays 3D-structure Chloroplast Metal-binding NAD NADP Oxidoreductase Plastid Reference proteome Transit peptide MLSTRTAAVA MLSTRTAAVAASASPASPWKLGGRSEGGASCDGCRTYRNTLRRRAAPAKVRALPPRRVDAVAMVSNAETETEKEQEEAAAASEELPVMPWATSVASGYTLLRDPHHNKGLAFTEEERDGHYLRGLLPPAVLSQELQIKKFMNTLRQYQTPLQRYIAMMNLQETDERLFYKLLIDNVVELLPFVYTPTVGEACQKYGSIFGRPQGLYVSLKDKGKVLEVLRNWPHRNIQVICVTDGERILGLGDLGCQGMGIPVGKLALYTALGGVDPSVCLPITIDVGTNNEFLLNDEFYIGLRQKRATGEEYDELIEEFMSAVKQFYGEKVLIQFEDFANHNAFDLLEKYSKSHLVFNDDIQGTASVVLAGLLAALKMVGGTLAEQTYLFLGAGEAGTGIAELIALEISKQTNAPIEECRKKVWLVDSKGLIVDSRKGSLQPFKKPWAHEHEPLKTLYDAVQSIKPTVLIGTSGVGRTFTKEIIEAMSSFNERPIIFSLSNPTSHSECTAEQAYTWSQGRSIFASGSPFAPVEYEGKTFVPGQSNNAYIFPGLGLGLVISGAVRVHEDMLLAASKALADQATQDNFEKGSIFPPFTSIRKISAHIAAAVAGKAYELGLATRLPPPSDLVKYAENCMYTPVYRNYR |
histidine biosynthetic process tryptophan biosynthetic process | cytoplasm | 1-(5-phosphoribosyl)-5-imidazole-4-carboxamide isomerase activity phosphoribosylanthranilate isomerase activity | Streptomyces coelicolor / M145) | 3D-structure Amino-acid biosynthesis Aromatic amino acid biosynthesis Cytoplasm Histidine biosynthesis Isomerase Reference proteome Tryptophan biosynthesis | MSKLELLPAV | MSKLELLPAVDVRDGQAVRLVHGESGTETSYGSPLEAALAWQRSGAEWLHLVDLDAAFGTGDNRALIAEVAQAMDIKVELSGGIRDDDTLAAALATGCTRVNLGTAALETPEWVAKVIAEHGDKIAVGLDVRGTTLRGRGWTRDGGDLYETLDRLNKEGCARYVVTDIAKDGTLQGPNLELLKNVCAATDRPVVASGGVSSLDDLRAIAGLVPAGVEGAIVGKALYAKAFTLEEALEATS | histidine biosynthetic process tryptophan biosynthetic process cytoplasm 1-(5-phosphoribosyl)-5-imidazole-4-carboxamide isomerase activity phosphoribosylanthranilate isomerase activity Streptomyces coelicolor / M145)3D-structure Amino-acid biosynthesis Aromatic amino acid biosynthesis Cytoplasm Histidine biosynthesis Isomerase Reference proteome Tryptophan biosynthesis MSKLELLPAV MSKLELLPAVDVRDGQAVRLVHGESGTETSYGSPLEAALAWQRSGAEWLHLVDLDAAFGTGDNRALIAEVAQAMDIKVELSGGIRDDDTLAAALATGCTRVNLGTAALETPEWVAKVIAEHGDKIAVGLDVRGTTLRGRGWTRDGGDLYETLDRLNKEGCARYVVTDIAKDGTLQGPNLELLKNVCAATDRPVVASGGVSSLDDLRAIAGLVPAGVEGAIVGKALYAKAFTLEEALEATS |
intracellular cholesterol transport sterol transport | cytosol; endoplasmic reticulum membrane; Golgi membrane; perinuclear region of cytoplasm; trans-Golgi network | cholesterol binding phosphatidylinositol-4-phosphate binding sterol transfer activity | Oryctolagus cuniculus | Acetylation Coiled coil Cytoplasm Direct protein sequencing Endoplasmic reticulum Golgi apparatus Lipid transport Lipid-binding Membrane Phosphoprotein Reference proteome Transport | MAATELRGVV | MAATELRGVVGPGPAAIAAPGGGGAGPPVVGGGGGGRGDAGPGSGAASGTVAAAAAGGQGPGAGGVAAAAGPAPTPPAGGSGSSGTGGSGSAREGWLFKWTNYIKGYQRRWFVLSNGLLSYYRSKAEMRHTCRGTINLATANITVEDSCNFIISNGGAQTYHLKASSEVERQRWVTALELAKAKAVKMLAESDESGDEESVSQTDKTELQNTLRTLSSKVEDLSTCNDLIAKHGTALQRSLSELESLKLPAESNEKIKQVNERATLFRITSNAMINACRDFLVLAQTHSKKWQKSLQYERDQRIRLEETLEQLAKQHNHLERAFRGATVLPAHTSGSAGSGKDQCCSGKGDMSDEDDENEFFDAPEIITMPENLGHKRTGSNISGASSDISLDEQYKHQLEETKKEKRTRIPYKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDRAAKCENSLEQLCYVAAFTVSSYSTTVFRTSKPFNPLLGETFELDRLEENGYRSLCEQVSHHPPAAAHHAESKNGWTLRQEIKITSKFRGKYLSIMPLGTIHCIFHATGHHYTWKKVTTTVHNIIVGKLWIDQSGEIDIVNHKTGDKCNLKFVPYSYFSRDVARKVTGEVTDPSGKVHFALLGTWDEKMDCFKVQPVSGENGGDARQRGHEAEESRVMLWKRNPLPKNAENMYYFSELALTLNAWEGGTAPTDSRLRPDQRLMENGRWDEANAEKQRLEEKQRLSRKKREAEAMKATEDGTPYDPYKALWFERKKDPVTKELTHIYRGEYWECKEKQDWNSCPDIF | intracellular cholesterol transport sterol transport cytosol; endoplasmic reticulum membrane; Golgi membrane; perinuclear region of cytoplasm; trans-Golgi network cholesterol binding phosphatidylinositol-4-phosphate binding sterol transfer activity Oryctolagus cuniculus Acetylation Coiled coil Cytoplasm Direct protein sequencing Endoplasmic reticulum Golgi apparatus Lipid transport Lipid-binding Membrane Phosphoprotein Reference proteome Transport MAATELRGVV MAATELRGVVGPGPAAIAAPGGGGAGPPVVGGGGGGRGDAGPGSGAASGTVAAAAAGGQGPGAGGVAAAAGPAPTPPAGGSGSSGTGGSGSAREGWLFKWTNYIKGYQRRWFVLSNGLLSYYRSKAEMRHTCRGTINLATANITVEDSCNFIISNGGAQTYHLKASSEVERQRWVTALELAKAKAVKMLAESDESGDEESVSQTDKTELQNTLRTLSSKVEDLSTCNDLIAKHGTALQRSLSELESLKLPAESNEKIKQVNERATLFRITSNAMINACRDFLVLAQTHSKKWQKSLQYERDQRIRLEETLEQLAKQHNHLERAFRGATVLPAHTSGSAGSGKDQCCSGKGDMSDEDDENEFFDAPEIITMPENLGHKRTGSNISGASSDISLDEQYKHQLEETKKEKRTRIPYKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDRAAKCENSLEQLCYVAAFTVSSYSTTVFRTSKPFNPLLGETFELDRLEENGYRSLCEQVSHHPPAAAHHAESKNGWTLRQEIKITSKFRGKYLSIMPLGTIHCIFHATGHHYTWKKVTTTVHNIIVGKLWIDQSGEIDIVNHKTGDKCNLKFVPYSYFSRDVARKVTGEVTDPSGKVHFALLGTWDEKMDCFKVQPVSGENGGDARQRGHEAEESRVMLWKRNPLPKNAENMYYFSELALTLNAWEGGTAPTDSRLRPDQRLMENGRWDEANAEKQRLEEKQRLSRKKREAEAMKATEDGTPYDPYKALWFERKKDPVTKELTHIYRGEYWECKEKQDWNSCPDIF |
electron transport coupled proton transport oxidative phosphorylation | plasma membrane; respirasome | cytochrome-c oxidase activity heme binding metal ion binding | Bacillus sp. | Cell membrane Copper Direct protein sequencing Electron transport Heme Iron Membrane Metal-binding Respiratory chain Translocase Transmembrane Transmembrane helix Transport | MSTIARKKGV | MSTIARKKGVGAVLWDYLTTVDHKKIAHLYLISGGFFFLLGGLEALFIRIQLAKPNNDFLVGGLYNEVLTMHGTTMIFLAAMPLVFAFMNAVVPLQIGARDVAFPFLNALGFWMFFFGGLFLNCSWFLGGAPDAGWTSYASLSLDSKAHHGIDFYTLGLQISGFGTIMGAINFLVTIINMRAPGMTFMRMPMFTWATFVTSALILFAFPPLTVGLIFMMMDRLFGGNFFNPAAGGNTIIWEHLFWVFGHPEVYILVLPAFGIFSEIFATFSRKRLFGYSSMVFATVLIAFLGFMVWAHHMFTVGMGPIANAIFAVATMTIAVPTGVKIFNWLFTMWGGSIKFTTPMHYAVAFIPSFVMGGVTGVMLASAAADYQYHDSYFVVAHFHYVIVGGVVFALLAGTHYWWPKMFGRMLNETLGKITFWLFFIGFHLTFFIQHFLGLTGMPRRVFTYLPHQGWETGNLISTIGAFFIAAATVILLINIVVTTAKGEKVPGDAWGDGRTLEWAIASPPPVYNFAQTPLVRGLDAFWLEKMEGKKELTPAEPLGDIHMPNSSFLPFVIAFGLFVAAFGFTYHNDAGWGLPVAILGLLITLGSMFLRSVIDDHGFHIHKEEVLEL | electron transport coupled proton transport oxidative phosphorylation plasma membrane; respirasome cytochrome-c oxidase activity heme binding metal ion binding Bacillus sp. Cell membrane Copper Direct protein sequencing Electron transport Heme Iron Membrane Metal-binding Respiratory chain Translocase Transmembrane Transmembrane helix Transport MSTIARKKGV MSTIARKKGVGAVLWDYLTTVDHKKIAHLYLISGGFFFLLGGLEALFIRIQLAKPNNDFLVGGLYNEVLTMHGTTMIFLAAMPLVFAFMNAVVPLQIGARDVAFPFLNALGFWMFFFGGLFLNCSWFLGGAPDAGWTSYASLSLDSKAHHGIDFYTLGLQISGFGTIMGAINFLVTIINMRAPGMTFMRMPMFTWATFVTSALILFAFPPLTVGLIFMMMDRLFGGNFFNPAAGGNTIIWEHLFWVFGHPEVYILVLPAFGIFSEIFATFSRKRLFGYSSMVFATVLIAFLGFMVWAHHMFTVGMGPIANAIFAVATMTIAVPTGVKIFNWLFTMWGGSIKFTTPMHYAVAFIPSFVMGGVTGVMLASAAADYQYHDSYFVVAHFHYVIVGGVVFALLAGTHYWWPKMFGRMLNETLGKITFWLFFIGFHLTFFIQHFLGLTGMPRRVFTYLPHQGWETGNLISTIGAFFIAAATVILLINIVVTTAKGEKVPGDAWGDGRTLEWAIASPPPVYNFAQTPLVRGLDAFWLEKMEGKKELTPAEPLGDIHMPNSSFLPFVIAFGLFVAAFGFTYHNDAGWGLPVAILGLLITLGSMFLRSVIDDHGFHIHKEEVLEL |
tricarboxylic acid cycle | cytosol; mitochondrion | 4 iron, 4 sulfur cluster binding aconitate hydratase activity metal ion binding | Sus scrofa | 3D-structure 4Fe-4S Acetylation Direct protein sequencing Iron Iron-sulfur Lyase Metal-binding Mitochondrion Phosphoprotein Pyrrolidone carboxylic acid Reference proteome Transit peptide Tricarboxylic acid cycle | MAPYSLLVTR | MAPYSLLVTRLQKALGVRQYHVASVLCQRAKVAMSHFEPHEYIRYDLLEKNIDIVRKRLNRPLTLSEKIVYGHLDDPANQEIERGKTYLRLRPDRVAMQDATAQMAMLQFISSGLPKVAVPSTIHCDHLIEAQLGGEKDLRRAKDINQEVYNFLATAGAKYGVGFWRPGSGIIHQIILENYAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPKVIGVKLTGSLSGWTSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYNHRMKKYLSKTGRADIANLADEFKDHLVPDPGCHYDQVIEINLSELKPHINGPFTPDLAHPVAEVGSVAEKEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAKQALAHGLKCKSQFTITPGSEQIRATIERDGYAQVLRDVGGIVLANACGPCIGQWDRKDIKKGEKNTIVTSYNRNFTGRNDANPETHAFVTSPEIVTALAIAGTLKFNPETDFLTGKDGKKFKLEAPDADELPRAEFDPGQDTYQHPPKDSSGQRVDVSPTSQRLQLLEPFDKWDGKDLEDLQILIKVKGKCTTDHISAAGPWLKFRGHLDNISNNLLIGAINIENRKANSVRNAVTQEFGPVPDTARYYKQHGIRWVVIGDENYGEGSSREHRALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPADYNKIHPVDKLTIQGLKDFAPGKPLKCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKELQQK | tricarboxylic acid cycle cytosol; mitochondrion 4 iron, 4 sulfur cluster binding aconitate hydratase activity metal ion binding Sus scrofa 3D-structure 4Fe-4S Acetylation Direct protein sequencing Iron Iron-sulfur Lyase Metal-binding Mitochondrion Phosphoprotein Pyrrolidone carboxylic acid Reference proteome Transit peptide Tricarboxylic acid cycle MAPYSLLVTR MAPYSLLVTRLQKALGVRQYHVASVLCQRAKVAMSHFEPHEYIRYDLLEKNIDIVRKRLNRPLTLSEKIVYGHLDDPANQEIERGKTYLRLRPDRVAMQDATAQMAMLQFISSGLPKVAVPSTIHCDHLIEAQLGGEKDLRRAKDINQEVYNFLATAGAKYGVGFWRPGSGIIHQIILENYAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPKVIGVKLTGSLSGWTSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYNHRMKKYLSKTGRADIANLADEFKDHLVPDPGCHYDQVIEINLSELKPHINGPFTPDLAHPVAEVGSVAEKEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAKQALAHGLKCKSQFTITPGSEQIRATIERDGYAQVLRDVGGIVLANACGPCIGQWDRKDIKKGEKNTIVTSYNRNFTGRNDANPETHAFVTSPEIVTALAIAGTLKFNPETDFLTGKDGKKFKLEAPDADELPRAEFDPGQDTYQHPPKDSSGQRVDVSPTSQRLQLLEPFDKWDGKDLEDLQILIKVKGKCTTDHISAAGPWLKFRGHLDNISNNLLIGAINIENRKANSVRNAVTQEFGPVPDTARYYKQHGIRWVVIGDENYGEGSSREHRALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPADYNKIHPVDKLTIQGLKDFAPGKPLKCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKELQQK |
B cell receptor signaling pathway cell differentiation innate immune response peptidyl-tyrosine phosphorylation positive regulation of insulin secretion transmembrane receptor protein tyrosine kinase signaling pathway | cytosol; extrinsic component of cytoplasmic side of plasma membrane | ATP binding non-membrane spanning protein tyrosine kinase activity protein tyrosine kinase activity signaling receptor binding | Mus musculus | 3D-structure ATP-binding Cell membrane Kinase Lipoprotein Membrane Myristate Nucleotide-binding Phosphoprotein Reference proteome SH2 domain SH3 domain Transferase Tyrosine-protein kinase Ubl conjugation | MGLLSSKRQV | MGLLSSKRQVSEKGKGWSPVKIRTQDKAPPPLPPLVVFNHLAPPSPNQDPDEEERFVVALFDYAAVNDRDLQVLKGEKLQVLRSTGDWWLARSLVTGREGYVPSNFVAPVETLEVEKWFFRTISRKDAERQLLAPMNKAGSFLIRESESNKGAFSLSVKDITTQGEVVKHYKIRSLDNGGYYISPRITFPTLQALVQHYSKKGDGLCQKLTLPCVNLAPKNLWAQDEWEIPRQSLKLVRKLGSGQFGEVWMGYYKNNMKVAIKTLKEGTMSPEAFLGEANVMKTLQHERLVRLYAVVTREPIYIVTEYMARGCLLDFLKTDEGSRLSLPRLIDMSAQVAEGMAYIERMNSIHRDLRAANILVSETLCCKIADFGLARIIDSEYTAQEGAKFPIKWTAPEAIHFGVFTIKADVWSFGVLLMEIVTYGRVPYPGMSNPEVIRSLEHGYRMPCPETCPPELYNDIITECWRGRPEERPTFEFLQSVLEDFYTATEGQYELQP | B cell receptor signaling pathway cell differentiation innate immune response peptidyl-tyrosine phosphorylation positive regulation of insulin secretion transmembrane receptor protein tyrosine kinase signaling pathway cytosol; extrinsic component of cytoplasmic side of plasma membrane ATP binding non-membrane spanning protein tyrosine kinase activity protein tyrosine kinase activity signaling receptor binding Mus musculus 3D-structure ATP-binding Cell membrane Kinase Lipoprotein Membrane Myristate Nucleotide-binding Phosphoprotein Reference proteome SH2 domain SH3 domain Transferase Tyrosine-protein kinase Ubl conjugation MGLLSSKRQV MGLLSSKRQVSEKGKGWSPVKIRTQDKAPPPLPPLVVFNHLAPPSPNQDPDEEERFVVALFDYAAVNDRDLQVLKGEKLQVLRSTGDWWLARSLVTGREGYVPSNFVAPVETLEVEKWFFRTISRKDAERQLLAPMNKAGSFLIRESESNKGAFSLSVKDITTQGEVVKHYKIRSLDNGGYYISPRITFPTLQALVQHYSKKGDGLCQKLTLPCVNLAPKNLWAQDEWEIPRQSLKLVRKLGSGQFGEVWMGYYKNNMKVAIKTLKEGTMSPEAFLGEANVMKTLQHERLVRLYAVVTREPIYIVTEYMARGCLLDFLKTDEGSRLSLPRLIDMSAQVAEGMAYIERMNSIHRDLRAANILVSETLCCKIADFGLARIIDSEYTAQEGAKFPIKWTAPEAIHFGVFTIKADVWSFGVLLMEIVTYGRVPYPGMSNPEVIRSLEHGYRMPCPETCPPELYNDIITECWRGRPEERPTFEFLQSVLEDFYTATEGQYELQP |
carbohydrate metabolic process galactose catabolic process glycosphingolipid catabolic process heparan sulfate proteoglycan catabolic process keratan sulfate catabolic process response to cortisone response to Thyroglobulin triiodothyronine | azurophil granule lumen; cytoplasm; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; Golgi apparatus; intracellular membrane-bounded organelle; lysosomal lumen; perinuclear region of cytoplasm; vacuole | beta-galactosidase activity galactoside binding protein homodimerization activity | Homo sapiens | 3D-structure Alternative splicing Cytoplasm Direct protein sequencing Disease variant Disulfide bond Gangliosidosis Glycoprotein Glycosidase Hydrolase Lysosome Mucopolysaccharidosis Reference proteome Signal Zymogen | MPGFLVRILP | MPGFLVRILPLLLVLLLLGPTRGLRNATQRMFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPSTPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVRSHLGGWGHRDSGHHDEAWAHNSSNYTLPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVTFVDRPVIGSSVTYDHPSKPVEKRLMPPPPQKNKDSWLDHV | carbohydrate metabolic process galactose catabolic process glycosphingolipid catabolic process heparan sulfate proteoglycan catabolic process keratan sulfate catabolic process response to cortisone response to Thyroglobulin triiodothyronine azurophil granule lumen; cytoplasm; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; Golgi apparatus; intracellular membrane-bounded organelle; lysosomal lumen; perinuclear region of cytoplasm; vacuole beta-galactosidase activity galactoside binding protein homodimerization activity Homo sapiens 3D-structure Alternative splicing Cytoplasm Direct protein sequencing Disease variant Disulfide bond Gangliosidosis Glycoprotein Glycosidase Hydrolase Lysosome Mucopolysaccharidosis Reference proteome Signal Zymogen MPGFLVRILP MPGFLVRILPLLLVLLLLGPTRGLRNATQRMFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPSTPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVRSHLGGWGHRDSGHHDEAWAHNSSNYTLPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVTFVDRPVIGSSVTYDHPSKPVEKRLMPPPPQKNKDSWLDHV |
bicellular tight junction assembly cell recognition cell surface receptor signaling pathway cell-cell adhesion cell-cell adhesion via plasma-membrane adhesion molecules diapedesis establishment of endothelial barrier glomerular endothelium development homophilic cell adhesion via plasma membrane adhesion molecules leukocyte cell-cell adhesion maintenance of blood-brain barrier monocyte extravasation neutrophil extravasation phagocytosis positive regulation of cell migration positive regulation of peptidyl-tyrosine phosphorylation positive regulation of protein localization to cell-cell junction positive regulation of protein phosphorylation signal transduction | cell-cell junction; extracellular exosome; extracellular space; membrane raft; plasma membrane; platelet alpha granule membrane; protein-containing complex; secretory granule membrane | protein homodimerization activity transmembrane signaling receptor activity | Homo sapiens | 3D-structure Alternative splicing Cell adhesion Cell junction Cell membrane Disulfide bond Glycoprotein Immunoglobulin domain Lipoprotein Membrane Palmitate Phagocytosis Phosphoprotein Reference proteome Repeat Signal Transmembrane Transmembrane helix | MQPRWAQGAT | MQPRWAQGATMWLGVLLTLLLCSSLEGQENSFTINSVDMKSLPDWTVQNGKNLTLQCFADVSTTSHVKPQHQMLFYKDDVLFYNISSMKSTESYFIPEVRIYDSGTYKCTVIVNNKEKTTAEYQVLVEGVPSPRVTLDKKEAIQGGIVRVNCSVPEEKAPIHFTIEKLELNEKMVKLKREKNSRDQNFVILEFPVEEQDRVLSFRCQARIISGIHMQTSESTKSELVTVTESFSTPKFHISPTGMIMEGAQLHIKCTIQVTHLAQEFPEIIIQKDKAIVAHNRHGNKAVYSVMAMVEHSGNYTCKVESSRISKVSSIVVNITELFSKPELESSFTHLDQGERLNLSCSIPGAPPANFTIQKEDTIVSQTQDFTKIASKSDSGTYICTAGIDKVVKKSNTVQIVVCEMLSQPRISYDAQFEVIKGQTIEVRCESISGTLPISYQLLKTSKVLENSTKNSNDPAVFKDNPTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDIVLQCAVNEGSGPITYKFYREKEGKPFYQMTSNATQAFWTKQKASKEQEGEYYCTAFNRANHASSVPRSKILTVRVILAPWKKGLIAVVIIGVIIALLIIAAKCYFLRKAKAKQMPVEMSRPAVPLLNSNNEKMSDPNMEANSHYGHNDDVRNHAMKPINDNKEPLNSDVQYTEVQVSSAESHKDLGKKDTETVYSEVRKAVPDAVESRYSRTEGSLDGT | bicellular tight junction assembly cell recognition cell surface receptor signaling pathway cell-cell adhesion cell-cell adhesion via plasma-membrane adhesion molecules diapedesis establishment of endothelial barrier glomerular endothelium development homophilic cell adhesion via plasma membrane adhesion molecules leukocyte cell-cell adhesion maintenance of blood-brain barrier monocyte extravasation neutrophil extravasation phagocytosis positive regulation of cell migration positive regulation of peptidyl-tyrosine phosphorylation positive regulation of protein localization to cell-cell junction positive regulation of protein phosphorylation signal transduction cell-cell junction; extracellular exosome; extracellular space; membrane raft; plasma membrane; platelet alpha granule membrane; protein-containing complex; secretory granule membrane protein homodimerization activity transmembrane signaling receptor activity Homo sapiens 3D-structure Alternative splicing Cell adhesion Cell junction Cell membrane Disulfide bond Glycoprotein Immunoglobulin domain Lipoprotein Membrane Palmitate Phagocytosis Phosphoprotein Reference proteome Repeat Signal Transmembrane Transmembrane helix MQPRWAQGAT MQPRWAQGATMWLGVLLTLLLCSSLEGQENSFTINSVDMKSLPDWTVQNGKNLTLQCFADVSTTSHVKPQHQMLFYKDDVLFYNISSMKSTESYFIPEVRIYDSGTYKCTVIVNNKEKTTAEYQVLVEGVPSPRVTLDKKEAIQGGIVRVNCSVPEEKAPIHFTIEKLELNEKMVKLKREKNSRDQNFVILEFPVEEQDRVLSFRCQARIISGIHMQTSESTKSELVTVTESFSTPKFHISPTGMIMEGAQLHIKCTIQVTHLAQEFPEIIIQKDKAIVAHNRHGNKAVYSVMAMVEHSGNYTCKVESSRISKVSSIVVNITELFSKPELESSFTHLDQGERLNLSCSIPGAPPANFTIQKEDTIVSQTQDFTKIASKSDSGTYICTAGIDKVVKKSNTVQIVVCEMLSQPRISYDAQFEVIKGQTIEVRCESISGTLPISYQLLKTSKVLENSTKNSNDPAVFKDNPTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDIVLQCAVNEGSGPITYKFYREKEGKPFYQMTSNATQAFWTKQKASKEQEGEYYCTAFNRANHASSVPRSKILTVRVILAPWKKGLIAVVIIGVIIALLIIAAKCYFLRKAKAKQMPVEMSRPAVPLLNSNNEKMSDPNMEANSHYGHNDDVRNHAMKPINDNKEPLNSDVQYTEVQVSSAESHKDLGKKDTETVYSEVRKAVPDAVESRYSRTEGSLDGT |
disruption by virus of host JAK-STAT cascade via inhibition of STAT1 activity disruption by virus of host JAK-STAT cascade via inhibition of STAT2 activity microtubule-dependent intracellular transport of viral material towards nucleus suppression by virus of host toll-like receptor signaling pathway suppression by virus of host transcription suppression by virus of host type I interferon-mediated signaling pathway suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity viral entry into host cell viral transcription | host cell cytoplasm; host cell nucleus; virion component | RNA-dependent RNA polymerase activity | Rabies virus | 3D-structure Alternative initiation Chaperone Cytoplasmic inwards viral transport Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Inhibition of host STAT1 by virus Inhibition of host STAT2 by virus Inhibition of host TBK1 by virus Inhibition of host TLR pathway by virus Interferon antiviral system evasion Microtubular inwards viral transport Phosphoprotein Viral immunoevasion Viral RNA replication Virion Virus entry into host cell | MSKIFVNPSA | MSKIFVNPSAIRAGLADLEMAEETVDLINRNIEDNQAHLQGEPIEVDNLPEDMGRLHLDDGKSPNHGEIAKVGEGKYREDFQMDEGEDPSFLFQSYLENVGVQIVRQMRSGERFLKIWSQTVEEIISYVAVNFPNPPGKSSEDKSTQTTGRELKKETTPTPSQRESQSSKARMAAQIASGPPALEWSATNEEDDLSVEAEIAHQIAESFSKKYKFPSRSSGILLYNFEQLKMNLDDIVKEAKNVPGVTRLAHDGSKLPLRCVLGWVALANSKKFQLLVESDKLSKIMQDDLNRYTSC | disruption by virus of host JAK-STAT cascade via inhibition of STAT1 activity disruption by virus of host JAK-STAT cascade via inhibition of STAT2 activity microtubule-dependent intracellular transport of viral material towards nucleus suppression by virus of host toll-like receptor signaling pathway suppression by virus of host transcription suppression by virus of host type I interferon-mediated signaling pathway suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity viral entry into host cell viral transcription host cell cytoplasm; host cell nucleus; virion component RNA-dependent RNA polymerase activity Rabies virus 3D-structure Alternative initiation Chaperone Cytoplasmic inwards viral transport Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Inhibition of host STAT1 by virus Inhibition of host STAT2 by virus Inhibition of host TBK1 by virus Inhibition of host TLR pathway by virus Interferon antiviral system evasion Microtubular inwards viral transport Phosphoprotein Viral immunoevasion Viral RNA replication Virion Virus entry into host cell MSKIFVNPSA MSKIFVNPSAIRAGLADLEMAEETVDLINRNIEDNQAHLQGEPIEVDNLPEDMGRLHLDDGKSPNHGEIAKVGEGKYREDFQMDEGEDPSFLFQSYLENVGVQIVRQMRSGERFLKIWSQTVEEIISYVAVNFPNPPGKSSEDKSTQTTGRELKKETTPTPSQRESQSSKARMAAQIASGPPALEWSATNEEDDLSVEAEIAHQIAESFSKKYKFPSRSSGILLYNFEQLKMNLDDIVKEAKNVPGVTRLAHDGSKLPLRCVLGWVALANSKKFQLLVESDKLSKIMQDDLNRYTSC |
negative regulation of viral transcription viral budding via host ESCRT complex | host cell cytoplasm; host cell endomembrane system; membrane; viral envelope; virion membrane | structural constituent of virion | Rabies virus | Apoptosis Host cytoplasm Host membrane Host-virus interaction Membrane Viral budding Viral budding via the host ESCRT complexes Viral envelope protein Viral matrix protein Viral release from host cell Virion | MNLLRKIVKN | MNLLRKIVKNRRDEDTQKSSPASAPLDDDDLWLPPPEYVPLKELTGKKNMRNFCINGRVKVCSPNGYSFRILRHILKSFDEIYSGNHRMIGLVKVVIGLALSGSPVPEGLNWVYKLRRTFIFQWADSRGPLEGEELEYSQEITWDDDTEFVGLQIRVIAKQCHIQGRVWCINMNPRACQLWSDMSLQTQRSEEDKDSSLLLE | negative regulation of viral transcription viral budding via host ESCRT complex host cell cytoplasm; host cell endomembrane system; membrane; viral envelope; virion membrane structural constituent of virion Rabies virus Apoptosis Host cytoplasm Host membrane Host-virus interaction Membrane Viral budding Viral budding via the host ESCRT complexes Viral envelope protein Viral matrix protein Viral release from host cell Virion MNLLRKIVKN MNLLRKIVKNRRDEDTQKSSPASAPLDDDDLWLPPPEYVPLKELTGKKNMRNFCINGRVKVCSPNGYSFRILRHILKSFDEIYSGNHRMIGLVKVVIGLALSGSPVPEGLNWVYKLRRTFIFQWADSRGPLEGEELEYSQEITWDDDTEFVGLQIRVIAKQCHIQGRVWCINMNPRACQLWSDMSLQTQRSEEDKDSSLLLE |
canonical glycolysis gluconeogenesis glycolytic process Notch signaling pathway response to inorganic substance response to mercury ion spermatogenesis striated muscle contraction | cytosol | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity bisphosphoglycerate mutase activity hydrolase activity identical protein binding phosphoglycerate mutase activity | Rattus norvegicus | Glycolysis Hydrolase Isomerase Phosphoprotein Reference proteome | MATHRLVMVR | MATHRLVMVRHGESSWNQENRFCGWFDAELSEKGAEEAKRGATAIKDAKIEFDICYTSVLKRAIRTLWTILDVTDQMWVPVVRTWRLNERHYGGLTGLNKAETAAKHGEEQVKIWRRSFDTPPPPMDEKHNYYASISKDRRYAGLKPEELPTCESLKDTIARALPFWNEEIAPKIKAGKRVLIAAHGNSLRGIVKHLEGMSDQAIMELNLPTGIPIVYELNQELKPTKPMRFLGDEETVRKAMEAVAAQGKAK | canonical glycolysis gluconeogenesis glycolytic process Notch signaling pathway response to inorganic substance response to mercury ion spermatogenesis striated muscle contraction cytosol 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity bisphosphoglycerate mutase activity hydrolase activity identical protein binding phosphoglycerate mutase activity Rattus norvegicus Glycolysis Hydrolase Isomerase Phosphoprotein Reference proteome MATHRLVMVR MATHRLVMVRHGESSWNQENRFCGWFDAELSEKGAEEAKRGATAIKDAKIEFDICYTSVLKRAIRTLWTILDVTDQMWVPVVRTWRLNERHYGGLTGLNKAETAAKHGEEQVKIWRRSFDTPPPPMDEKHNYYASISKDRRYAGLKPEELPTCESLKDTIARALPFWNEEIAPKIKAGKRVLIAAHGNSLRGIVKHLEGMSDQAIMELNLPTGIPIVYELNQELKPTKPMRFLGDEETVRKAMEAVAAQGKAK |
blood coagulation proteolysis zymogen activation | extracellular space | calcium ion binding endopeptidase activity serine-type endopeptidase activity | Sus scrofa | 3D-structure Blood coagulation Calcium Direct protein sequencing Disulfide bond EGF-like domain Gamma-carboxyglutamic acid Glycoprotein Hemostasis Hydrolase Hydroxylation Magnesium Metal-binding Phosphoprotein Protease Reference proteome Repeat Secreted Serine protease Sulfation Zymogen | YNSGKLEESF | YNSGKLEESFVRGNLERECIEEKCSFEEAREVFENTEKTNEFWKQYVDGDQCEPNPCLNGGLCKDDINSYECWCQVGFEGKNCELDATCNIKNGRCKQFCKTGADSKVLCSCTTGYRLAPDQKSCKPAVPFPCGRVSVSHSPTTLTRAEIIFSNMDYENSTEVEPILDSLTESNQSSDDFIRIVGGENAKPGQFPWQVLLNGKIDAFCGGSIINEKWVVTAAHCIEPGVKITVVAGEYNTEETEPTEQRRNVIRAIPHHSYNATVNKYSHDIALLELDEPLTLNSYVTPICIADKEYTNIFLKFGSGYVSGWGRVFNRGRSATILQYLKVPLVDRATCLRSTKVTIYSNMFCAGFHEGGKDSCLGDSGGPHVTEVEGTSFLTGIISWGEECAVKGKYGIYTKVSRYVNW | blood coagulation proteolysis zymogen activation extracellular space calcium ion binding endopeptidase activity serine-type endopeptidase activity Sus scrofa 3D-structure Blood coagulation Calcium Direct protein sequencing Disulfide bond EGF-like domain Gamma-carboxyglutamic acid Glycoprotein Hemostasis Hydrolase Hydroxylation Magnesium Metal-binding Phosphoprotein Protease Reference proteome Repeat Secreted Serine protease Sulfation Zymogen YNSGKLEESF YNSGKLEESFVRGNLERECIEEKCSFEEAREVFENTEKTNEFWKQYVDGDQCEPNPCLNGGLCKDDINSYECWCQVGFEGKNCELDATCNIKNGRCKQFCKTGADSKVLCSCTTGYRLAPDQKSCKPAVPFPCGRVSVSHSPTTLTRAEIIFSNMDYENSTEVEPILDSLTESNQSSDDFIRIVGGENAKPGQFPWQVLLNGKIDAFCGGSIINEKWVVTAAHCIEPGVKITVVAGEYNTEETEPTEQRRNVIRAIPHHSYNATVNKYSHDIALLELDEPLTLNSYVTPICIADKEYTNIFLKFGSGYVSGWGRVFNRGRSATILQYLKVPLVDRATCLRSTKVTIYSNMFCAGFHEGGKDSCLGDSGGPHVTEVEGTSFLTGIISWGEECAVKGKYGIYTKVSRYVNW |
blood coagulation proteolysis zymogen activation | extracellular space | calcium ion binding endopeptidase activity metal ion binding peptidase activity serine-type endopeptidase activity | Mus musculus | Blood coagulation Calcium Cleavage on pair of basic residues Disulfide bond EGF-like domain Gamma-carboxyglutamic acid Glycoprotein Hemostasis Hydrolase Hydroxylation Magnesium Metal-binding Phosphoprotein Protease Reference proteome Repeat Secreted Serine protease Signal Sulfation Zymogen | MKHLNTVMAE | MKHLNTVMAESPALITIFLLGYLLSTECAVFLDRENATKILTRPKRYNSGKLEEFVRGNLERECIEERCSFEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNGGICKDDISSYECWCQVGFEGRNCELDATCNIKNGRCKQFCKNSPDNKVICSCTEGYQLAEDQKSCEPTVPFPCGRASISYSSKKITRAETVFSNMDYENSTEAVFIQDDITDGAILNNVTESSESLNDFTRVVGGENAKPGQIPWQVILNGEIEAFCGGAIINEKWIVTAAHCLKPGDKIEVVAGEYNIDKKEDTEQRRNVIRTIPHHQYNATINKYSHDIALLELDKPLILNSYVTPICVANREYTNIFLKFGSGYVSGWGKVFNKGRQASILQYLRVPLVDRATCLRSTTFTIYNNMFCAGYREGGKDSCEGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT | blood coagulation proteolysis zymogen activation extracellular space calcium ion binding endopeptidase activity metal ion binding peptidase activity serine-type endopeptidase activity Mus musculus Blood coagulation Calcium Cleavage on pair of basic residues Disulfide bond EGF-like domain Gamma-carboxyglutamic acid Glycoprotein Hemostasis Hydrolase Hydroxylation Magnesium Metal-binding Phosphoprotein Protease Reference proteome Repeat Secreted Serine protease Signal Sulfation Zymogen MKHLNTVMAE MKHLNTVMAESPALITIFLLGYLLSTECAVFLDRENATKILTRPKRYNSGKLEEFVRGNLERECIEERCSFEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNGGICKDDISSYECWCQVGFEGRNCELDATCNIKNGRCKQFCKNSPDNKVICSCTEGYQLAEDQKSCEPTVPFPCGRASISYSSKKITRAETVFSNMDYENSTEAVFIQDDITDGAILNNVTESSESLNDFTRVVGGENAKPGQIPWQVILNGEIEAFCGGAIINEKWIVTAAHCLKPGDKIEVVAGEYNIDKKEDTEQRRNVIRTIPHHQYNATINKYSHDIALLELDKPLILNSYVTPICVANREYTNIFLKFGSGYVSGWGKVFNKGRQASILQYLRVPLVDRATCLRSTTFTIYNNMFCAGYREGGKDSCEGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT |
blood coagulation proteolysis zymogen activation | extracellular space | calcium ion binding endopeptidase activity metal ion binding peptidase activity serine-type endopeptidase activity | Rattus norvegicus | Blood coagulation Calcium Disulfide bond EGF-like domain Gamma-carboxyglutamic acid Glycoprotein Hemostasis Hydrolase Hydroxylation Magnesium Metal-binding Phosphoprotein Protease Reference proteome Secreted Serine protease Signal Sulfation Zymogen | MADAPGLIPI | MADAPGLIPIFLLGYLLSTECAVFLDRENATKILTRPKRYNSGKLEEFVQGNLERECIEERCSFEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNGGICKDDINSYECWCQAGFEGRNCELDATCSIKNGRCKQFCKNSPDNKIICSCTEGYQLAEDQKSCEPAVPFPCGRVSVAYNSKKITRAETVFSNTDYGNSTELILDDITNSTILDNLTENSEPINDFTRVVGGENAKPGQIPWQVILNGEIEAFCGGAIINEKWIVTAAHCLKPGDKIEVVAGEHNIDEKEDTEQRRNVIRTIPHHQYNATINKYSHDIALLELDKPLILNSYVTPICVANKEYTNIFLKFGSGYVSGWGKVFNKGRQASILQYLRVPLVDRATCLRSTKFSIYNNMFCAGYREGGKDSCEGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT | blood coagulation proteolysis zymogen activation extracellular space calcium ion binding endopeptidase activity metal ion binding peptidase activity serine-type endopeptidase activity Rattus norvegicus Blood coagulation Calcium Disulfide bond EGF-like domain Gamma-carboxyglutamic acid Glycoprotein Hemostasis Hydrolase Hydroxylation Magnesium Metal-binding Phosphoprotein Protease Reference proteome Secreted Serine protease Signal Sulfation Zymogen MADAPGLIPI MADAPGLIPIFLLGYLLSTECAVFLDRENATKILTRPKRYNSGKLEEFVQGNLERECIEERCSFEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNGGICKDDINSYECWCQAGFEGRNCELDATCSIKNGRCKQFCKNSPDNKIICSCTEGYQLAEDQKSCEPAVPFPCGRVSVAYNSKKITRAETVFSNTDYGNSTELILDDITNSTILDNLTENSEPINDFTRVVGGENAKPGQIPWQVILNGEIEAFCGGAIINEKWIVTAAHCLKPGDKIEVVAGEHNIDEKEDTEQRRNVIRTIPHHQYNATINKYSHDIALLELDKPLILNSYVTPICVANKEYTNIFLKFGSGYVSGWGKVFNKGRQASILQYLRVPLVDRATCLRSTKFSIYNNMFCAGYREGGKDSCEGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT |
cytokine-mediated signaling pathway immunoglobulin mediated immune response interleukin-15-mediated signaling pathway interleukin-2-mediated signaling pathway negative regulation of apoptotic process positive regulation of phagocytosis | cell surface; external side of plasma membrane; plasma membrane | coreceptor activity cytokine receptor activity interleukin-15 receptor activity interleukin-2 binding interleukin-2 receptor activity | Mus musculus | 3D-structure Cell membrane Disulfide bond Glycoprotein Membrane Receptor Reference proteome Signal Transmembrane Transmembrane helix | MATIALPWSL | MATIALPWSLSLYVFLLLLATPWASAAVKNCSHLECFYNSRANVSCMWSHEEALNVTTCHVHAKSNLRHWNKTCELTLVRQASWACNLILGSFPESQSLTSVDLLDINVVCWEEKGWRRVKTCDFHPFDNLRLVAPHSLQVLHIDTQRCNISWKVSQVSHYIEPYLEFEARRRLLGHSWEDASVLSLKQRQQWLFLEMLIPSTSYEVQVRVKAQRNNTGTWSPWSQPLTFRTRPADPMKEILPMSWLRYLLLVLGCFSGFFSCVYILVKCRYLGPWLKTVLKCHIPDPSEFFSQLSSQHGGDLQKWLSSPVPLSFFSPSGPAPEISPLEVLDGDSKAVQLLLLQKDSAPLPSPSGHSQASCFTNQGYFFFHLPNALEIESCQVYFTYDPCVEEEVEEDGSRLPEGSPHPPLLPLAGEQDDYCAFPPRDDLLLFSPSLSTPNTAYGGSRAPEERSPLSLHEGLPSLASRDLMGLQRPLERMPEGDGEGLSANSSGEQASVPEGNLHGQDQDRGQGPILTLNTDAYLSLQELQAQDSVHLI | cytokine-mediated signaling pathway immunoglobulin mediated immune response interleukin-15-mediated signaling pathway interleukin-2-mediated signaling pathway negative regulation of apoptotic process positive regulation of phagocytosis cell surface; external side of plasma membrane; plasma membrane coreceptor activity cytokine receptor activity interleukin-15 receptor activity interleukin-2 binding interleukin-2 receptor activity Mus musculus 3D-structure Cell membrane Disulfide bond Glycoprotein Membrane Receptor Reference proteome Signal Transmembrane Transmembrane helix MATIALPWSL MATIALPWSLSLYVFLLLLATPWASAAVKNCSHLECFYNSRANVSCMWSHEEALNVTTCHVHAKSNLRHWNKTCELTLVRQASWACNLILGSFPESQSLTSVDLLDINVVCWEEKGWRRVKTCDFHPFDNLRLVAPHSLQVLHIDTQRCNISWKVSQVSHYIEPYLEFEARRRLLGHSWEDASVLSLKQRQQWLFLEMLIPSTSYEVQVRVKAQRNNTGTWSPWSQPLTFRTRPADPMKEILPMSWLRYLLLVLGCFSGFFSCVYILVKCRYLGPWLKTVLKCHIPDPSEFFSQLSSQHGGDLQKWLSSPVPLSFFSPSGPAPEISPLEVLDGDSKAVQLLLLQKDSAPLPSPSGHSQASCFTNQGYFFFHLPNALEIESCQVYFTYDPCVEEEVEEDGSRLPEGSPHPPLLPLAGEQDDYCAFPPRDDLLLFSPSLSTPNTAYGGSRAPEERSPLSLHEGLPSLASRDLMGLQRPLERMPEGDGEGLSANSSGEQASVPEGNLHGQDQDRGQGPILTLNTDAYLSLQELQAQDSVHLI |
cholesterol homeostasis cholesterol metabolic process cholesterol transport high-density lipoprotein particle remodeling lipid metabolic process lipoprotein biosynthetic process lipoprotein metabolic process phosphatidylcholine biosynthetic process phosphatidylcholine metabolic process phospholipid metabolic process regulation of high-density lipoprotein particle assembly response to copper ion response to glucocorticoid reverse cholesterol transport very-low-density lipoprotein particle remodeling | extracellular space; high-density lipoprotein particle | 1-alkyl-2-acetylglycerophosphocholine esterase activity apolipoprotein A-I binding phosphatidylcholine-sterol O-acyltransferase activity phospholipase A2 activity platelet-activating factor acetyltransferase activity sterol esterase activity | Mus musculus | Acyltransferase Cholesterol metabolism Disulfide bond Glycoprotein Hydrolase Lipid metabolism Reference proteome Secreted Signal Steroid metabolism Sterol metabolism Transferase | MGLPGSPWQR | MGLPGSPWQRVLLLLGLLLPPATPFWLLNVLFPPHTTPKAELSNHTRPVILVPGCLGNRLEAKLDKPDVVNWMCYRKTEDFFTIWLDFNLFLPLGVDCWIDNTRIVYNHSSGRVSNAPGVQIRVPGFGKTESVEYVDDNKLAGYLHTLVQNLVNNGYVRDETVRAAPYDWRLAPHQQDEYYKKLAGLVEEMYAAYGKPVFLIGHSLGCLHVLHFLLRQPQSWKDHFIDGFISLGAPWGGSIKAMRILASGDNQGIPILSNIKLKEEQRITTTSPWMLPAPHVWPEDHVFISTPNFNYTVQDFERFFTDLHFEEGWHMFLQSRDLLERLPAPGVEVYCLYGVGRPTPHTYIYDHNFPYKDPVAALYEDGDDTVATRSTELCGQWQGRQSQPVHLLPMNETDHLNMVFSNKTLEHINAILLGAYRTPKSPAASPSPPPPE | cholesterol homeostasis cholesterol metabolic process cholesterol transport high-density lipoprotein particle remodeling lipid metabolic process lipoprotein biosynthetic process lipoprotein metabolic process phosphatidylcholine biosynthetic process phosphatidylcholine metabolic process phospholipid metabolic process regulation of high-density lipoprotein particle assembly response to copper ion response to glucocorticoid reverse cholesterol transport very-low-density lipoprotein particle remodeling extracellular space; high-density lipoprotein particle 1-alkyl-2-acetylglycerophosphocholine esterase activity apolipoprotein A-I binding phosphatidylcholine-sterol O-acyltransferase activity phospholipase A2 activity platelet-activating factor acetyltransferase activity sterol esterase activity Mus musculus Acyltransferase Cholesterol metabolism Disulfide bond Glycoprotein Hydrolase Lipid metabolism Reference proteome Secreted Signal Steroid metabolism Sterol metabolism Transferase MGLPGSPWQR MGLPGSPWQRVLLLLGLLLPPATPFWLLNVLFPPHTTPKAELSNHTRPVILVPGCLGNRLEAKLDKPDVVNWMCYRKTEDFFTIWLDFNLFLPLGVDCWIDNTRIVYNHSSGRVSNAPGVQIRVPGFGKTESVEYVDDNKLAGYLHTLVQNLVNNGYVRDETVRAAPYDWRLAPHQQDEYYKKLAGLVEEMYAAYGKPVFLIGHSLGCLHVLHFLLRQPQSWKDHFIDGFISLGAPWGGSIKAMRILASGDNQGIPILSNIKLKEEQRITTTSPWMLPAPHVWPEDHVFISTPNFNYTVQDFERFFTDLHFEEGWHMFLQSRDLLERLPAPGVEVYCLYGVGRPTPHTYIYDHNFPYKDPVAALYEDGDDTVATRSTELCGQWQGRQSQPVHLLPMNETDHLNMVFSNKTLEHINAILLGAYRTPKSPAASPSPPPPE |
acylglycerol catabolic process cellular response to cholesterol cellular response to cold cellular response to low-density lipoprotein particle stimulus cholesterol biosynthetic process cholesterol homeostasis cholesterol metabolic process circadian temperature homeostasis cold-induced thermogenesis cytosolic lipolysis epithelial cell differentiation lipid catabolic process medium-chain fatty acid metabolic process negative regulation of cholesterol storage positive regulation of cholesterol efflux positive regulation of cholesterol metabolic process positive regulation of transcription by RNA polymerase II regulation of bile acid biosynthetic process regulation of bile acid secretion retinoid metabolic process reverse cholesterol transport short-chain fatty acid catabolic process very-low-density lipoprotein particle assembly | cytoplasm; cytosol; endoplasmic reticulum; endoplasmic reticulum lumen; intracellular membrane-bounded organelle; lipid droplet | all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity carboxylesterase activity carboxylic ester hydrolase activity fatty-acyl-ethyl-ester synthase activity retinyl-palmitate esterase activity sterol esterase activity triglyceride lipase activity | Rattus norvegicus | Cytoplasm Direct protein sequencing Disulfide bond Endoplasmic reticulum Glycoprotein Hydrolase Lipid degradation Lipid droplet Lipid metabolism Microsome Reference proteome Serine esterase Signal | MRLYPLVWLF | MRLYPLVWLFLAACTAWGYPSSPPVVNTVKGKVLGKYVNLEGFAQPVAVFLGIPFAKPPLGSLRFAPPQPAEPWNFVKNTTSYPPMCSQDAVGGQVLSELFTNRKENIPLQFSEDCLYLNVYTPADLTKNSRLPVMVWIHGGGLVVGGASTYDGQVLSAHENVVVVTIQYRLGIWGFFSTGDEHSQGNWGHLDQVAALHWVQDNIANFGGNPGSVTIFGESAGGFSVSALVLSPLAKNLFHRAISESGVVLTSALITTDSKPIANLIATLSGCKTTTSAVMVHCLRQKTEDELLETSLKLNLFKLDLLGNPKESYPFLPTVIDGVVLPKTPEEILAEKSFNTVPYIVGINKQEFGWIIPTLMGYPLSEGKLDQKTAKSLLWKSYPTLKISEKMIPVVAEKYFGGTDDPAKRKDLFQDLVADVMFGVPSVMVSRSHRDAGAPTFMYEFEYRPSFVSAMRPKTVIGDHGDELFSVFGSPFLKDGASEEETNLSKMVMKYWANFARNGNPNGGGLPHWPEYDQKEGYLKIGASTQAAQRLKDKEVAFWSELRAKEAAEEPSHWKHVEL | acylglycerol catabolic process cellular response to cholesterol cellular response to cold cellular response to low-density lipoprotein particle stimulus cholesterol biosynthetic process cholesterol homeostasis cholesterol metabolic process circadian temperature homeostasis cold-induced thermogenesis cytosolic lipolysis epithelial cell differentiation lipid catabolic process medium-chain fatty acid metabolic process negative regulation of cholesterol storage positive regulation of cholesterol efflux positive regulation of cholesterol metabolic process positive regulation of transcription by RNA polymerase II regulation of bile acid biosynthetic process regulation of bile acid secretion retinoid metabolic process reverse cholesterol transport short-chain fatty acid catabolic process very-low-density lipoprotein particle assembly cytoplasm; cytosol; endoplasmic reticulum; endoplasmic reticulum lumen; intracellular membrane-bounded organelle; lipid droplet all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity carboxylesterase activity carboxylic ester hydrolase activity fatty-acyl-ethyl-ester synthase activity retinyl-palmitate esterase activity sterol esterase activity triglyceride lipase activity Rattus norvegicus Cytoplasm Direct protein sequencing Disulfide bond Endoplasmic reticulum Glycoprotein Hydrolase Lipid degradation Lipid droplet Lipid metabolism Microsome Reference proteome Serine esterase Signal MRLYPLVWLF MRLYPLVWLFLAACTAWGYPSSPPVVNTVKGKVLGKYVNLEGFAQPVAVFLGIPFAKPPLGSLRFAPPQPAEPWNFVKNTTSYPPMCSQDAVGGQVLSELFTNRKENIPLQFSEDCLYLNVYTPADLTKNSRLPVMVWIHGGGLVVGGASTYDGQVLSAHENVVVVTIQYRLGIWGFFSTGDEHSQGNWGHLDQVAALHWVQDNIANFGGNPGSVTIFGESAGGFSVSALVLSPLAKNLFHRAISESGVVLTSALITTDSKPIANLIATLSGCKTTTSAVMVHCLRQKTEDELLETSLKLNLFKLDLLGNPKESYPFLPTVIDGVVLPKTPEEILAEKSFNTVPYIVGINKQEFGWIIPTLMGYPLSEGKLDQKTAKSLLWKSYPTLKISEKMIPVVAEKYFGGTDDPAKRKDLFQDLVADVMFGVPSVMVSRSHRDAGAPTFMYEFEYRPSFVSAMRPKTVIGDHGDELFSVFGSPFLKDGASEEETNLSKMVMKYWANFARNGNPNGGGLPHWPEYDQKEGYLKIGASTQAAQRLKDKEVAFWSELRAKEAAEEPSHWKHVEL |
AMP salvage nucleoside diphosphate metabolic process nucleoside monophosphate metabolic process phosphorylation | cytoplasm; cytosol | adenylate kinase activity ATP binding nucleoside diphosphate kinase activity zinc ion binding | Bacillus subtilis | 3D-structure ATP-binding Cytoplasm Direct protein sequencing Kinase Metal-binding Nucleotide biosynthesis Nucleotide-binding Reference proteome Transferase Zinc | MNLVLMGLPG | MNLVLMGLPGAGKGTQGERIVEDYGIPHISTGDMFRAAMKEETPLGLEAKSYIDKGELVPDEVTIGIVKERLGKDDCERGFLLDGFPRTVAQAEALEEILEEYGKPIDYVINIEVDKDVLMERLTGRRICSVCGTTYHLVFNPPKTPGICDKDGGELYQRADDNEETVSKRLEVNMKQTQPLLDFYSEKGYLANVNGQQDIQDVYADVKDLLGGLKK | AMP salvage nucleoside diphosphate metabolic process nucleoside monophosphate metabolic process phosphorylation cytoplasm; cytosol adenylate kinase activity ATP binding nucleoside diphosphate kinase activity zinc ion binding Bacillus subtilis 3D-structure ATP-binding Cytoplasm Direct protein sequencing Kinase Metal-binding Nucleotide biosynthesis Nucleotide-binding Reference proteome Transferase Zinc MNLVLMGLPG MNLVLMGLPGAGKGTQGERIVEDYGIPHISTGDMFRAAMKEETPLGLEAKSYIDKGELVPDEVTIGIVKERLGKDDCERGFLLDGFPRTVAQAEALEEILEEYGKPIDYVINIEVDKDVLMERLTGRRICSVCGTTYHLVFNPPKTPGICDKDGGELYQRADDNEETVSKRLEVNMKQTQPLLDFYSEKGYLANVNGQQDIQDVYADVKDLLGGLKK |
chloride transmembrane transport gamma-aminobutyric acid signaling pathway regulation of postsynaptic membrane potential synaptic transmission, GABAergic | cerebellar Golgi cell to granule cell synapse; chloride channel complex; dendrite; dendrite membrane; GABA-A receptor complex; GABA-ergic synapse; hippocampal mossy fiber to CA3 synapse; neuron projection; neuronal cell body membrane; postsynapse; postsynaptic membrane; postsynaptic specialization membrane; presynaptic membrane; receptor complex; synapse | diazepam binding GABA-A receptor activity GABA-gated chloride ion channel activity heterocyclic compound binding inhibitory extracellular ligand-gated monoatomic ion channel activity protein-containing complex binding transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | Mus musculus | Alternative splicing Cell membrane Chloride Chloride channel Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Phosphoprotein Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MVLLLPWLFI | MVLLLPWLFIILWLENAQAQLEDEGNFYSENVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLKFKGPAEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRLMQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGSYAYPKTEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQSQKAERQAQTAATPPVAKSKASESLQAEIVVHSDSKYHLKKRISSLTLPIVPSSEASKALSRTPILKSTPVSPPLLLPATGGTSKIDQYSRILFPVAFAGFNLVYWIVYLSKDTMEVSSTVE | chloride transmembrane transport gamma-aminobutyric acid signaling pathway regulation of postsynaptic membrane potential synaptic transmission, GABAergic cerebellar Golgi cell to granule cell synapse; chloride channel complex; dendrite; dendrite membrane; GABA-A receptor complex; GABA-ergic synapse; hippocampal mossy fiber to CA3 synapse; neuron projection; neuronal cell body membrane; postsynapse; postsynaptic membrane; postsynaptic specialization membrane; presynaptic membrane; receptor complex; synapse diazepam binding GABA-A receptor activity GABA-gated chloride ion channel activity heterocyclic compound binding inhibitory extracellular ligand-gated monoatomic ion channel activity protein-containing complex binding transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential Mus musculus Alternative splicing Cell membrane Chloride Chloride channel Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Phosphoprotein Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport MVLLLPWLFI MVLLLPWLFIILWLENAQAQLEDEGNFYSENVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLKFKGPAEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRLMQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGSYAYPKTEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQSQKAERQAQTAATPPVAKSKASESLQAEIVVHSDSKYHLKKRISSLTLPIVPSSEASKALSRTPILKSTPVSPPLLLPATGGTSKIDQYSRILFPVAFAGFNLVYWIVYLSKDTMEVSSTVE |
cartilage development involved in endochondral bone morphogenesis cellular response to hormone stimulus cellular response to insulin stimulus cytokine-mediated signaling pathway endocytosis growth hormone receptor signaling pathway hormone metabolic process hormone-mediated signaling pathway insulin-like growth factor receptor signaling pathway positive regulation of cell differentiation positive regulation of MAP kinase activity positive regulation of multicellular organism growth positive regulation of peptidyl-tyrosine phosphorylation positive regulation of receptor signaling pathway via JAK-STAT receptor signaling pathway via JAK-STAT regulation of multicellular organism growth regulation of response to nutrient levels response to cytokine response to food response to glucocorticoid response to gravity response to growth hormone response to hormone response to interleukin-1 response to peptide hormone taurine metabolic process | cell surface; cytoplasmic ribonucleoprotein granule; cytosol; external side of plasma membrane; extracellular space; growth hormone receptor complex; membrane; neuronal cell body; nucleus; plasma membrane; receptor complex | cytokine binding growth factor binding growth hormone receptor activity identical protein binding lipid binding peptide hormone binding protein homodimerization activity protein kinase binding protein phosphatase binding SH2 domain binding | Rattus norvegicus | Alternative splicing Cell membrane Disulfide bond Endocytosis Glycoprotein Membrane Phosphoprotein Receptor Reference proteome Secreted Signal Transmembrane Transmembrane helix Ubl conjugation | MDLWRVFLTL | MDLWRVFLTLALAVSSDMFPGSGATPATLGKASPVLQRINPSLRESSSGKPRFTKCRSPELETFSCYWTEGDDHNLKVPGSIQLYYARRIAHEWTPEWKECPDYVSAGANSCYFNSSYTSIWIPYCIKLTTNGDLLDEKCFTVDEIVQPDPPIGLNWTLLNISLPGIRGDIQVSWQPPPSADVLKGWIILEYEIQYKEVNETKWKTMSPIWSTSVPLYSLRLDKEHEVRVRSRQRSFEKYSEFSEVLRVTFPQMDTLAACEEDFRFPWFLIIIFGIFGVAVMLFVVIFSKQQRIKMLILPPVPVPKIKGIDPDLLKEGKLEEVNTILGIHDNYKPDFYNDDSWVEFIELDIDDADEKTEESDTDRLLSDDQEKSAGILGAKDDDSGRTSCYDPDILDTDFHTSDMCDGTSEFAQPQKLKAEADLLCLDQKNLKNSPYDASLGSLHPSITLTMEDKPQPLLGSETESTHQLPSTPMSSPVSLANIDFYAQVSDITPAGGVVLSPGQKIKAGLAQGNTQLEVAAPCQENYSMNSAYFCESDAKKCIAAAPHMEATTCVKPSFNQEDIYITTESLTTTARMSETADTAPDAEPVPDYTTVHTVKSPRGLILNATALPLPDKKKFLSSCGYVSTDQLNKIMQ | cartilage development involved in endochondral bone morphogenesis cellular response to hormone stimulus cellular response to insulin stimulus cytokine-mediated signaling pathway endocytosis growth hormone receptor signaling pathway hormone metabolic process hormone-mediated signaling pathway insulin-like growth factor receptor signaling pathway positive regulation of cell differentiation positive regulation of MAP kinase activity positive regulation of multicellular organism growth positive regulation of peptidyl-tyrosine phosphorylation positive regulation of receptor signaling pathway via JAK-STAT receptor signaling pathway via JAK-STAT regulation of multicellular organism growth regulation of response to nutrient levels response to cytokine response to food response to glucocorticoid response to gravity response to growth hormone response to hormone response to interleukin-1 response to peptide hormone taurine metabolic process cell surface; cytoplasmic ribonucleoprotein granule; cytosol; external side of plasma membrane; extracellular space; growth hormone receptor complex; membrane; neuronal cell body; nucleus; plasma membrane; receptor complex cytokine binding growth factor binding growth hormone receptor activity identical protein binding lipid binding peptide hormone binding protein homodimerization activity protein kinase binding protein phosphatase binding SH2 domain binding Rattus norvegicus Alternative splicing Cell membrane Disulfide bond Endocytosis Glycoprotein Membrane Phosphoprotein Receptor Reference proteome Secreted Signal Transmembrane Transmembrane helix Ubl conjugation MDLWRVFLTL MDLWRVFLTLALAVSSDMFPGSGATPATLGKASPVLQRINPSLRESSSGKPRFTKCRSPELETFSCYWTEGDDHNLKVPGSIQLYYARRIAHEWTPEWKECPDYVSAGANSCYFNSSYTSIWIPYCIKLTTNGDLLDEKCFTVDEIVQPDPPIGLNWTLLNISLPGIRGDIQVSWQPPPSADVLKGWIILEYEIQYKEVNETKWKTMSPIWSTSVPLYSLRLDKEHEVRVRSRQRSFEKYSEFSEVLRVTFPQMDTLAACEEDFRFPWFLIIIFGIFGVAVMLFVVIFSKQQRIKMLILPPVPVPKIKGIDPDLLKEGKLEEVNTILGIHDNYKPDFYNDDSWVEFIELDIDDADEKTEESDTDRLLSDDQEKSAGILGAKDDDSGRTSCYDPDILDTDFHTSDMCDGTSEFAQPQKLKAEADLLCLDQKNLKNSPYDASLGSLHPSITLTMEDKPQPLLGSETESTHQLPSTPMSSPVSLANIDFYAQVSDITPAGGVVLSPGQKIKAGLAQGNTQLEVAAPCQENYSMNSAYFCESDAKKCIAAAPHMEATTCVKPSFNQEDIYITTESLTTTARMSETADTAPDAEPVPDYTTVHTVKSPRGLILNATALPLPDKKKFLSSCGYVSTDQLNKIMQ |
proteolysis | extracellular region | cysteine-type peptidase activity | Dermatophagoides farinae | 3D-structure Allergen Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Protease Secreted Signal Thiol protease Zymogen | MKFVLAIASL | MKFVLAIASLLVLSTVYARPASIKTFEEFKKAFNKNYATVEEEEVARKNFLESLKYVEANKGAINHLSDLSLDEFKNRYLMSAEAFEQLKTQFDLNAETSACRINSVNVPSELDLRSLRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNTSLDLSEQELVDCASQHGCHGDTIPRGIEYIQQNGVVEERSYPYVAREQRCRRPNSQHYGISNYCQIYPPDVKQIREALTQTHTAIAVIIGIKDLRAFQHYDGRTIIQHDNGYQPNYHAVNIVGYGSTQGDDYWIVRNSWDTTWGDSGYGYFQAGNNLMMIEQYPYVVIM | proteolysis extracellular region cysteine-type peptidase activity Dermatophagoides farinae 3D-structure Allergen Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Protease Secreted Signal Thiol protease Zymogen MKFVLAIASL MKFVLAIASLLVLSTVYARPASIKTFEEFKKAFNKNYATVEEEEVARKNFLESLKYVEANKGAINHLSDLSLDEFKNRYLMSAEAFEQLKTQFDLNAETSACRINSVNVPSELDLRSLRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNTSLDLSEQELVDCASQHGCHGDTIPRGIEYIQQNGVVEERSYPYVAREQRCRRPNSQHYGISNYCQIYPPDVKQIREALTQTHTAIAVIIGIKDLRAFQHYDGRTIIQHDNGYQPNYHAVNIVGYGSTQGDDYWIVRNSWDTTWGDSGYGYFQAGNNLMMIEQYPYVVIM |
adult locomotory behavior axonogenesis cyclic nucleotide catabolic process forebrain development oligodendrocyte differentiation regulation of mitochondrial membrane permeability response to lipopolysaccharide response to toxic substance | cell projection; cytoplasm; extracellular space; melanosome; membrane; microtubule; microvillus; mitochondrial inner membrane; mitochondrial outer membrane; myelin sheath; myelin sheath abaxonal region; myelin sheath adaxonal region; perinuclear region of cytoplasm; pseudopodium | 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity cyclic nucleotide binding RNA binding | Mus musculus | 3D-structure Alternative splicing Direct protein sequencing Hydrolase Lipoprotein Membrane Methylation Phosphoprotein Prenylation Reference proteome RNA-binding | MNTSFTRKSH | MNTSFTRKSHTFLPKLFFRKMSSSGAKEKPELQFPFLQDEDTVATLHECKTLFILRGLPGSGKSTLARLILEKYHDGTKMVSADAYKIIPGSRADFSEAYKRLDEDLAGYCRRDIRVLVLDDTNHERERLDQLFEMADQYQYQVVLVEPKTAWRLDCAQLKEKNQWQLSADDLKKLKPGLEKDFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFISGDEPKEKLELVSYFGKRPPGVLHCTTKFCDYGKAAGAEEYAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQELQLWPSDLDKPSASEGLPPGSRAHVTLGCAADVQPVQTGLDLLDILQQVKGGSQGEAVGELPRGKLYSLGKGRWMLSLTKKMEVKAIFTGYYGKGKPVPIHGSRKGGAMQICTII | adult locomotory behavior axonogenesis cyclic nucleotide catabolic process forebrain development oligodendrocyte differentiation regulation of mitochondrial membrane permeability response to lipopolysaccharide response to toxic substance cell projection; cytoplasm; extracellular space; melanosome; membrane; microtubule; microvillus; mitochondrial inner membrane; mitochondrial outer membrane; myelin sheath; myelin sheath abaxonal region; myelin sheath adaxonal region; perinuclear region of cytoplasm; pseudopodium 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity cyclic nucleotide binding RNA binding Mus musculus 3D-structure Alternative splicing Direct protein sequencing Hydrolase Lipoprotein Membrane Methylation Phosphoprotein Prenylation Reference proteome RNA-binding MNTSFTRKSH MNTSFTRKSHTFLPKLFFRKMSSSGAKEKPELQFPFLQDEDTVATLHECKTLFILRGLPGSGKSTLARLILEKYHDGTKMVSADAYKIIPGSRADFSEAYKRLDEDLAGYCRRDIRVLVLDDTNHERERLDQLFEMADQYQYQVVLVEPKTAWRLDCAQLKEKNQWQLSADDLKKLKPGLEKDFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFISGDEPKEKLELVSYFGKRPPGVLHCTTKFCDYGKAAGAEEYAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQELQLWPSDLDKPSASEGLPPGSRAHVTLGCAADVQPVQTGLDLLDILQQVKGGSQGEAVGELPRGKLYSLGKGRWMLSLTKKMEVKAIFTGYYGKGKPVPIHGSRKGGAMQICTII |
homocysteine metabolic process post-embryonic development propionate metabolic process, methylmalonyl pathway succinyl-CoA biosynthetic process | cytoplasm; mitochondrial matrix; mitochondrion | cobalamin binding GTPase activity identical protein binding metal ion binding methylmalonyl-CoA mutase activity modified amino acid binding protein homodimerization activity | Mus musculus | Acetylation Cobalamin Cobalt Cytoplasm Isomerase Metal-binding Mitochondrion Phosphoprotein Reference proteome Transit peptide | MLRAKNQLFL | MLRAKNQLFLLSPHYLKQLNIPSASRWKRLLHQQQPLHPEWAVLAKKQLKGKNPEDLIWHTPEGISIKPLYSRADTLDLPEELPGVKPFTRGPYPTMYTYRPWTIRQYAGFSTVEESNKFYKDNIKAGQQGLSVAFDLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNGAVIPVLATFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFQYTAQHMPKFNSISISGYHMQEAGADAILELAYTIADGLEYCRTGLQAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWAHLIEKMFQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIVRTAIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMESLTNDVYEAALKLIYEVEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKEDSVEVLAIDNTSVRKKQIEKLKKIKSSRDQALAEQCLSALTQCAASGDGNILALAVDAARARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESKEITSAIKRVNKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGVSTLAAGHKTLVPELIKELTALGRPDILVMCGGVIPPQDYEFLYEVGVSNVFGPGTRIPRAAVQVLDDIEKCLAEKQQSV | homocysteine metabolic process post-embryonic development propionate metabolic process, methylmalonyl pathway succinyl-CoA biosynthetic process cytoplasm; mitochondrial matrix; mitochondrion cobalamin binding GTPase activity identical protein binding metal ion binding methylmalonyl-CoA mutase activity modified amino acid binding protein homodimerization activity Mus musculus Acetylation Cobalamin Cobalt Cytoplasm Isomerase Metal-binding Mitochondrion Phosphoprotein Reference proteome Transit peptide MLRAKNQLFL MLRAKNQLFLLSPHYLKQLNIPSASRWKRLLHQQQPLHPEWAVLAKKQLKGKNPEDLIWHTPEGISIKPLYSRADTLDLPEELPGVKPFTRGPYPTMYTYRPWTIRQYAGFSTVEESNKFYKDNIKAGQQGLSVAFDLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNGAVIPVLATFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFQYTAQHMPKFNSISISGYHMQEAGADAILELAYTIADGLEYCRTGLQAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWAHLIEKMFQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIVRTAIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMESLTNDVYEAALKLIYEVEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKEDSVEVLAIDNTSVRKKQIEKLKKIKSSRDQALAEQCLSALTQCAASGDGNILALAVDAARARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESKEITSAIKRVNKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGVSTLAAGHKTLVPELIKELTALGRPDILVMCGGVIPPQDYEFLYEVGVSNVFGPGTRIPRAAVQVLDDIEKCLAEKQQSV |
negative regulation of membrane protein ectodomain proteolysis response to cytokine response to hormone | extracellular matrix; extracellular space | metal ion binding metalloendopeptidase inhibitor activity protease binding | Bos taurus | 3D-structure Direct protein sequencing Disulfide bond Metal-binding Metalloenzyme inhibitor Metalloprotease inhibitor Protease inhibitor Reference proteome Secreted Signal Zinc | MGAAARSLPL | MGAAARSLPLAFCLLLLGTLLPRADACSCSPVHPQQAFCNADIVIRAKAVNKKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPDQDIEFIYTAPAAAVCGVSLDIGGKKEYLIAGKAEGNGNMHITLCDFIVPWDTLSATQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKNINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP | negative regulation of membrane protein ectodomain proteolysis response to cytokine response to hormone extracellular matrix; extracellular space metal ion binding metalloendopeptidase inhibitor activity protease binding Bos taurus 3D-structure Direct protein sequencing Disulfide bond Metal-binding Metalloenzyme inhibitor Metalloprotease inhibitor Protease inhibitor Reference proteome Secreted Signal Zinc MGAAARSLPL MGAAARSLPLAFCLLLLGTLLPRADACSCSPVHPQQAFCNADIVIRAKAVNKKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPDQDIEFIYTAPAAAVCGVSLDIGGKKEYLIAGKAEGNGNMHITLCDFIVPWDTLSATQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKNINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP |
RNA-templated transcription termination of RNA polymerase II transcription transcription by RNA polymerase II transcription elongation by RNA polymerase II transcription initiation at RNA polymerase II promoter | nucleoplasm; nucleus; RNA polymerase II, core complex | DNA binding DNA-directed 5'-3' RNA polymerase activity metal ion binding protein dimerization activity | Saccharomyces cerevisiae | 3D-structure Acetylation Direct protein sequencing DNA-directed RNA polymerase Metal-binding Nucleus Reference proteome Transcription Zinc | MSEEGPQVKI | MSEEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIVSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYDPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVDQVVVRGIDTLQKKVASILLALTQMDQDKVNFASGDNNTASNMLGSNEDVMMTGAEQDPYSNASQMGNTGSGGYDNAW | RNA-templated transcription termination of RNA polymerase II transcription transcription by RNA polymerase II transcription elongation by RNA polymerase II transcription initiation at RNA polymerase II promoter nucleoplasm; nucleus; RNA polymerase II, core complex DNA binding DNA-directed 5'-3' RNA polymerase activity metal ion binding protein dimerization activity Saccharomyces cerevisiae 3D-structure Acetylation Direct protein sequencing DNA-directed RNA polymerase Metal-binding Nucleus Reference proteome Transcription Zinc MSEEGPQVKI MSEEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIVSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYDPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVDQVVVRGIDTLQKKVASILLALTQMDQDKVNFASGDNNTASNMLGSNEDVMMTGAEQDPYSNASQMGNTGSGGYDNAW |
cell differentiation epidermal growth factor receptor signaling pathway fibroblast growth factor receptor signaling pathway negative regulation of canonical Wnt signaling pathway negative regulation of DNA-templated transcription negative regulation of Toll signaling pathway negative regulation of transcription by RNA polymerase II nervous system development regulation of DNA-templated transcription sex determination, primary response to X:A ratio torso signaling pathway Wnt signaling pathway | nucleoplasm; nucleus; protein-containing complex; transcription regulator complex | CRD domain binding DNA-binding transcription factor binding HMG box domain binding transcription corepressor activity transcription factor binding | Drosophila melanogaster | Alternative splicing Developmental protein Differentiation Neurogenesis Nucleus Phosphoprotein Reference proteome Repeat Repressor Transcription Transcription regulation Ubl conjugation WD repeat Wnt signaling pathway | MYPSPVRHPA | MYPSPVRHPAAGGPPPQGPIKFTIADTLERIKEEFNFLQAQYHSIKLECEKLSNEKTEMQRHYVMYYEMSYGLNVEMHKQTEIAKRLNTLINQLLPFLQADHQQQVLQAVERAKQVTMQELNLIIGHQQQHGIQQLLQQIHAQQVPGGPPQPMGALNPFGALGATMGLPHGPQGLLNKPPEHHRPDIKPTGLEGPAAAEERLRNSVSPADREKYRTRSPLDIENDSKRRKDEKLQEDEGEKSDQDLVVDVANEMESHSPRPNGEHVSMEVRDRESLNGERLEKPSSSGIKQERPPSRSGSSSSRSTPSLKTKDMEKPGTPGAKARTPTPNAAAPAPGVNPKQMMPQGPPPAGYPGAPYQRPADPYQRPPSDPAYGRPPPMPYDPHAHVRTNGIPHPSALTGGKPAYSFHMNGEGSLQPVPFPPDALVGVGIPRHARQINTLSHGEVVCAVTISNPTKYVYTGGKGCVKVWDISQPGNKNPVSQLDCLQRDNYIRSVKLLPDGRTLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSCCSDGNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVRSWDLREGRQLQQHDFSSQIFSLGYCPTGDWLAVGMENSHVEVLHASKPDKYQLHLHESCVLSLRFAACGKWFVSTGKDNLLNAWRTPYGASIFQSKETSSVLSCDISTDDKYIVTGSGDKKATVYEVIY | cell differentiation epidermal growth factor receptor signaling pathway fibroblast growth factor receptor signaling pathway negative regulation of canonical Wnt signaling pathway negative regulation of DNA-templated transcription negative regulation of Toll signaling pathway negative regulation of transcription by RNA polymerase II nervous system development regulation of DNA-templated transcription sex determination, primary response to X:A ratio torso signaling pathway Wnt signaling pathway nucleoplasm; nucleus; protein-containing complex; transcription regulator complex CRD domain binding DNA-binding transcription factor binding HMG box domain binding transcription corepressor activity transcription factor binding Drosophila melanogaster Alternative splicing Developmental protein Differentiation Neurogenesis Nucleus Phosphoprotein Reference proteome Repeat Repressor Transcription Transcription regulation Ubl conjugation WD repeat Wnt signaling pathway MYPSPVRHPA MYPSPVRHPAAGGPPPQGPIKFTIADTLERIKEEFNFLQAQYHSIKLECEKLSNEKTEMQRHYVMYYEMSYGLNVEMHKQTEIAKRLNTLINQLLPFLQADHQQQVLQAVERAKQVTMQELNLIIGHQQQHGIQQLLQQIHAQQVPGGPPQPMGALNPFGALGATMGLPHGPQGLLNKPPEHHRPDIKPTGLEGPAAAEERLRNSVSPADREKYRTRSPLDIENDSKRRKDEKLQEDEGEKSDQDLVVDVANEMESHSPRPNGEHVSMEVRDRESLNGERLEKPSSSGIKQERPPSRSGSSSSRSTPSLKTKDMEKPGTPGAKARTPTPNAAAPAPGVNPKQMMPQGPPPAGYPGAPYQRPADPYQRPPSDPAYGRPPPMPYDPHAHVRTNGIPHPSALTGGKPAYSFHMNGEGSLQPVPFPPDALVGVGIPRHARQINTLSHGEVVCAVTISNPTKYVYTGGKGCVKVWDISQPGNKNPVSQLDCLQRDNYIRSVKLLPDGRTLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSCCSDGNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVRSWDLREGRQLQQHDFSSQIFSLGYCPTGDWLAVGMENSHVEVLHASKPDKYQLHLHESCVLSLRFAACGKWFVSTGKDNLLNAWRTPYGASIFQSKETSSVLSCDISTDDKYIVTGSGDKKATVYEVIY |
anatomical structure development cardioblast cell fate determination cell differentiation epithelial cell proliferation involved in Malpighian tubule morphogenesis fat body development glial cell development heart development neuroblast development neuron-neuron synaptic transmission photoreceptor cell differentiation phototaxis R1/R6 cell fate commitment R3/R4 cell fate commitment regulation of transcription by RNA polymerase II ventral cord development visual perception | cytoplasm; nucleus; synapse | DNA-binding transcription repressor activity, RNA polymerase II-specific nuclear receptor activity protein heterodimerization activity protein homodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding zinc ion binding | Drosophila melanogaster | Alternative splicing DNA-binding Metal-binding Nucleus Receptor Reference proteome Sensory transduction Transcription Transcription regulation Vision Zinc Zinc-finger | MCASPSTAPG | MCASPSTAPGFFNPRPQSGAELSAFDIGLSRSMGLGVPPHSAWHEPPASLGGHLHAASAGPGTTTGSVATGGGGTTPSSVASQQSAVIKQDLSCPSLNQAGSGHHPGIKEDLSSSLPSANGGSAGGHHSGSGSGSGSGVNPGHGSDMLPLIKGHGQDMLTSIKGQPTGCGSTTPSSQANSSHSQSSNSGSQIDSKQNIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYSCRGSRNCPIDQHHRNQCQYCRLKKCLKMGMRREAVQRGRVPPTQPGLAGMHGQYQIANGDPMGIAGFNGHSYLSSYISLLLRAEPYPTSRYGQCMQPNNIMGIDNICELAARLLFSAVEWAKNIPFFPELQVTDQVALLRLVWSELFVLNASQCSMPLHVAPLLAAAGLHASPMAADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTTDACGLSDVTHIESLQEKSQCALEEYCRTQYPNQPTRFGKLLLRLPSLRTVSSQVIEQLFFVRLVGKTPIETLIRDMLLSGNSFSWPYLPSM | anatomical structure development cardioblast cell fate determination cell differentiation epithelial cell proliferation involved in Malpighian tubule morphogenesis fat body development glial cell development heart development neuroblast development neuron-neuron synaptic transmission photoreceptor cell differentiation phototaxis R1/R6 cell fate commitment R3/R4 cell fate commitment regulation of transcription by RNA polymerase II ventral cord development visual perception cytoplasm; nucleus; synapse DNA-binding transcription repressor activity, RNA polymerase II-specific nuclear receptor activity protein heterodimerization activity protein homodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding zinc ion binding Drosophila melanogaster Alternative splicing DNA-binding Metal-binding Nucleus Receptor Reference proteome Sensory transduction Transcription Transcription regulation Vision Zinc Zinc-finger MCASPSTAPG MCASPSTAPGFFNPRPQSGAELSAFDIGLSRSMGLGVPPHSAWHEPPASLGGHLHAASAGPGTTTGSVATGGGGTTPSSVASQQSAVIKQDLSCPSLNQAGSGHHPGIKEDLSSSLPSANGGSAGGHHSGSGSGSGSGVNPGHGSDMLPLIKGHGQDMLTSIKGQPTGCGSTTPSSQANSSHSQSSNSGSQIDSKQNIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYSCRGSRNCPIDQHHRNQCQYCRLKKCLKMGMRREAVQRGRVPPTQPGLAGMHGQYQIANGDPMGIAGFNGHSYLSSYISLLLRAEPYPTSRYGQCMQPNNIMGIDNICELAARLLFSAVEWAKNIPFFPELQVTDQVALLRLVWSELFVLNASQCSMPLHVAPLLAAAGLHASPMAADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTTDACGLSDVTHIESLQEKSQCALEEYCRTQYPNQPTRFGKLLLRLPSLRTVSSQVIEQLFFVRLVGKTPIETLIRDMLLSGNSFSWPYLPSM |
anatomical structure development cardioblast cell fate determination cell differentiation epithelial cell proliferation involved in Malpighian tubule morphogenesis fat body development glial cell development glucose homeostasis heart development lipid homeostasis neuroblast development neuron-neuron synaptic transmission photoreceptor cell differentiation phototaxis R1/R6 cell fate commitment R3/R4 cell fate commitment regulation of lipid storage regulation of transcription by RNA polymerase II ventral cord development visual perception | cytoplasm; nucleus; synapse | DNA-binding transcription repressor activity, RNA polymerase II-specific nuclear receptor activity protein heterodimerization activity protein homodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding zinc ion binding | Drosophila melanogaster | Alternative splicing DNA-binding Metal-binding Nucleus Receptor Reference proteome Sensory transduction Transcription Transcription regulation Vision Zinc Zinc-finger | MCASPSTAPG | MCASPSTAPGFFNPRPQSGAELSAFDIGLSRSMGLGVPPHSAWHEPPASLGGHLHAASAGPGTTTGSVATGGGGTTPSSVASQQSAVIKQDLSCPSLNQAGSGHHPGIKEDLSSSLPSANGGSAGGHHSGSGSGSGSGVNPGHGSDMLPLIKGHGQDMLTSIKGQPTGCGSTTPSSQANSSHSQSSNSGSQIDSKQNIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYSCRGSRNCPIDQHHRNQCQYCRLKKCLKMGMRREAVQRGRVPPTQPGLAGMHGQYQIANGDPMGIAGFNGHSYLSSYISLLLRAEPYPTSRYGQCMQPNNIMGIDNICELAARLLFSAVEWAKNIPFFPELQVTDQVALLRLVWSELFVLNASQCSMPLHVAPLLAAAGLHASPMAADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTTGKLLDILYKDVPALLTKVSALLGKGSTASNDDVLAVVRDHLDELNRQEQESQAQQQAPLHLAAFMNCVAGVEAAVQQAEQAQVPTSSASASVSAPLVPSAGSAFSSCQAKSAGSEMDLLASLYAQAQATPPSSGGGDASGHNNSSGLGASLPTQSQSGSSSRNLTASPLSTSLATAPAPASASAPAPVPTSSVAQVPVPAPVPVTSSASSSSLGGGAYQTPSAAAAAAAMFHYQTPPRAAFGSAFDMFHHSTPFGVGVGHAHALAHSSGSGSASFGSPSYRYSPYSLAGSRWQL | anatomical structure development cardioblast cell fate determination cell differentiation epithelial cell proliferation involved in Malpighian tubule morphogenesis fat body development glial cell development glucose homeostasis heart development lipid homeostasis neuroblast development neuron-neuron synaptic transmission photoreceptor cell differentiation phototaxis R1/R6 cell fate commitment R3/R4 cell fate commitment regulation of lipid storage regulation of transcription by RNA polymerase II ventral cord development visual perception cytoplasm; nucleus; synapse DNA-binding transcription repressor activity, RNA polymerase II-specific nuclear receptor activity protein heterodimerization activity protein homodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding zinc ion binding Drosophila melanogaster Alternative splicing DNA-binding Metal-binding Nucleus Receptor Reference proteome Sensory transduction Transcription Transcription regulation Vision Zinc Zinc-finger MCASPSTAPG MCASPSTAPGFFNPRPQSGAELSAFDIGLSRSMGLGVPPHSAWHEPPASLGGHLHAASAGPGTTTGSVATGGGGTTPSSVASQQSAVIKQDLSCPSLNQAGSGHHPGIKEDLSSSLPSANGGSAGGHHSGSGSGSGSGVNPGHGSDMLPLIKGHGQDMLTSIKGQPTGCGSTTPSSQANSSHSQSSNSGSQIDSKQNIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYSCRGSRNCPIDQHHRNQCQYCRLKKCLKMGMRREAVQRGRVPPTQPGLAGMHGQYQIANGDPMGIAGFNGHSYLSSYISLLLRAEPYPTSRYGQCMQPNNIMGIDNICELAARLLFSAVEWAKNIPFFPELQVTDQVALLRLVWSELFVLNASQCSMPLHVAPLLAAAGLHASPMAADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTTGKLLDILYKDVPALLTKVSALLGKGSTASNDDVLAVVRDHLDELNRQEQESQAQQQAPLHLAAFMNCVAGVEAAVQQAEQAQVPTSSASASVSAPLVPSAGSAFSSCQAKSAGSEMDLLASLYAQAQATPPSSGGGDASGHNNSSGLGASLPTQSQSGSSSRNLTASPLSTSLATAPAPASASAPAPVPTSSVAQVPVPAPVPVTSSASSSSLGGGAYQTPSAAAAAAAMFHYQTPPRAAFGSAFDMFHHSTPFGVGVGHAHALAHSSGSGSASFGSPSYRYSPYSLAGSRWQL |
adenylate cyclase-modulating G protein-coupled receptor signaling pathway asymmetric cell division axon ensheathment in central nervous system behavioral response to starvation calcium-mediated signaling cell adhesion involved in heart morphogenesis cortical actin cytoskeleton organization establishment of glial blood-brain barrier establishment of imaginal disc-derived wing hair orientation G protein-coupled receptor signaling pathway heart development negative regulation of synaptic assembly at neuromuscular junction non-canonical Wnt signaling pathway sensory perception of sweet taste septate junction assembly ventral cord development | heterotrimeric G-protein complex; plasma membrane | G protein-coupled receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity metal ion binding | Drosophila melanogaster | Alternative splicing GTP-binding Lipoprotein Magnesium Metal-binding Myristate Nucleotide-binding Palmitate Reference proteome Transducer | MGCAQSAEER | MGCAQSAEERAAAARSRLIERNLKEDGIQAAKDIKLLLLGAGESGKSTIVKQMKIIHESGFTAEDFKQYRPVVYSNTIQSLVAILRAMPTLSIQYSNNERESDAKMVFDVCQRMHDTEPFSEELLAAMKRLWQDAGVQECFSRSNEYQLNDSAKYFLDDLDRLGAKDYQPTEQDILRTRVKTTGIVEVHFSFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDSICNNKWFTDTSIILFLNKKDLFEEKIRKSPLTICFPEYTGGQEYGEAAAYIQAQFEAKNKSTSKEIYCHMTCATDTNNIQFVFDAVTDVIIANNLRGCGLY | adenylate cyclase-modulating G protein-coupled receptor signaling pathway asymmetric cell division axon ensheathment in central nervous system behavioral response to starvation calcium-mediated signaling cell adhesion involved in heart morphogenesis cortical actin cytoskeleton organization establishment of glial blood-brain barrier establishment of imaginal disc-derived wing hair orientation G protein-coupled receptor signaling pathway heart development negative regulation of synaptic assembly at neuromuscular junction non-canonical Wnt signaling pathway sensory perception of sweet taste septate junction assembly ventral cord development heterotrimeric G-protein complex; plasma membrane G protein-coupled receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity metal ion binding Drosophila melanogaster Alternative splicing GTP-binding Lipoprotein Magnesium Metal-binding Myristate Nucleotide-binding Palmitate Reference proteome Transducer MGCAQSAEER MGCAQSAEERAAAARSRLIERNLKEDGIQAAKDIKLLLLGAGESGKSTIVKQMKIIHESGFTAEDFKQYRPVVYSNTIQSLVAILRAMPTLSIQYSNNERESDAKMVFDVCQRMHDTEPFSEELLAAMKRLWQDAGVQECFSRSNEYQLNDSAKYFLDDLDRLGAKDYQPTEQDILRTRVKTTGIVEVHFSFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDSICNNKWFTDTSIILFLNKKDLFEEKIRKSPLTICFPEYTGGQEYGEAAAYIQAQFEAKNKSTSKEIYCHMTCATDTNNIQFVFDAVTDVIIANNLRGCGLY |
cytokine-mediated signaling pathway defense response to protozoan immunoglobulin mediated immune response interleukin-4-mediated signaling pathway negative regulation of T-helper 1 cell differentiation positive regulation of chemokine production positive regulation of cold-induced thermogenesis positive regulation of immunoglobulin production positive regulation of macrophage activation positive regulation of mast cell degranulation positive regulation of myoblast fusion positive regulation of T-helper 2 cell differentiation production of molecular mediator involved in inflammatory response regulation of cell population proliferation T-helper 1 cell differentiation T-helper 2 cell differentiation | centriolar satellite; external side of plasma membrane; extracellular space; nucleoplasm; plasma membrane; receptor complex | cytokine receptor activity interleukin-4 receptor activity | Mus musculus | Alternative splicing Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Immunity Membrane Phosphoprotein Receptor Reference proteome Secreted Signal Transmembrane Transmembrane helix | MGRLCTKFLT | MGRLCTKFLTSVGCLILLLVTGSGSIKVLGEPTCFSDYIRTSTCEWFLDSAVDCSSQLCLHYRLMFFEFSENLTCIPRNSASTVCVCHMEMNRPVQSDRYQMELWAEHRQLWQGSFSPSGNVKPLAPDNLTLHTNVSDEWLLTWNNLYPSNNLLYKDLISMVNISREDNPAEFIVYNVTYKEPRLSFPINILMSGVYYTARVRVRSQILTGTWSEWSPSITWYNHFQLPLIQRLPLGVTISCLCIPLFCLFCYFSITKIKKIWWDQIPTPARSPLVAIIIQDAQVPLWDKQTRSQESTKYPHWKTCLDKLLPCLLKHRVKKKTDFPKAAPTKSLQSPGKAGWCPMEVSRTVLWPENVSVSVVRCMELFEAPVQNVEEEEDEIVKEDLSMSPENSGGCGFQESQADIMARLTENLFSDLLEAENGGLGQSALAESCSPLPSGSGQASVSWACLPMGPSEEATCQVTEQPSHPGPLSGSPAQSAPTLACTQVPLVLADNPAYRSFSDCCSPAPNPGELAPEQQQADHLEEEEPPSPADPHSSGPPMQPVESWEQILHMSVLQHGAAAGSTPAPAGGYQEFVQAVKQGAAQDPGVPGVRPSGDPGYKAFSSLLSSNGIRGDTAAAGTDDGHGGYKPFQNPVPNQSPSSVPLFTFGLDTELSPSPLNSDPPKSPPECLGLELGLKGGDWVKAPPPADQVPKPFGDDLGFGIVYSSLTCHLCGHLKQHHSQEEGGQSPIVASPGCGCCYDDRSPSLGSLSGALESCPEGIPPEANLMSAPKTPSNLSGEGKGPGHSPVPSQTTEVPVGALGIAVS | cytokine-mediated signaling pathway defense response to protozoan immunoglobulin mediated immune response interleukin-4-mediated signaling pathway negative regulation of T-helper 1 cell differentiation positive regulation of chemokine production positive regulation of cold-induced thermogenesis positive regulation of immunoglobulin production positive regulation of macrophage activation positive regulation of mast cell degranulation positive regulation of myoblast fusion positive regulation of T-helper 2 cell differentiation production of molecular mediator involved in inflammatory response regulation of cell population proliferation T-helper 1 cell differentiation T-helper 2 cell differentiation centriolar satellite; external side of plasma membrane; extracellular space; nucleoplasm; plasma membrane; receptor complex cytokine receptor activity interleukin-4 receptor activity Mus musculus Alternative splicing Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Immunity Membrane Phosphoprotein Receptor Reference proteome Secreted Signal Transmembrane Transmembrane helix MGRLCTKFLT MGRLCTKFLTSVGCLILLLVTGSGSIKVLGEPTCFSDYIRTSTCEWFLDSAVDCSSQLCLHYRLMFFEFSENLTCIPRNSASTVCVCHMEMNRPVQSDRYQMELWAEHRQLWQGSFSPSGNVKPLAPDNLTLHTNVSDEWLLTWNNLYPSNNLLYKDLISMVNISREDNPAEFIVYNVTYKEPRLSFPINILMSGVYYTARVRVRSQILTGTWSEWSPSITWYNHFQLPLIQRLPLGVTISCLCIPLFCLFCYFSITKIKKIWWDQIPTPARSPLVAIIIQDAQVPLWDKQTRSQESTKYPHWKTCLDKLLPCLLKHRVKKKTDFPKAAPTKSLQSPGKAGWCPMEVSRTVLWPENVSVSVVRCMELFEAPVQNVEEEEDEIVKEDLSMSPENSGGCGFQESQADIMARLTENLFSDLLEAENGGLGQSALAESCSPLPSGSGQASVSWACLPMGPSEEATCQVTEQPSHPGPLSGSPAQSAPTLACTQVPLVLADNPAYRSFSDCCSPAPNPGELAPEQQQADHLEEEEPPSPADPHSSGPPMQPVESWEQILHMSVLQHGAAAGSTPAPAGGYQEFVQAVKQGAAQDPGVPGVRPSGDPGYKAFSSLLSSNGIRGDTAAAGTDDGHGGYKPFQNPVPNQSPSSVPLFTFGLDTELSPSPLNSDPPKSPPECLGLELGLKGGDWVKAPPPADQVPKPFGDDLGFGIVYSSLTCHLCGHLKQHHSQEEGGQSPIVASPGCGCCYDDRSPSLGSLSGALESCPEGIPPEANLMSAPKTPSNLSGEGKGPGHSPVPSQTTEVPVGALGIAVS |
mRNA splicing, via spliceosome negative regulation of DNA-templated transcription regulation of DNA-templated transcription spliceosomal complex assembly | cytosol; nucleolus; nucleoplasm; nucleus; U2-type post-mRNA release spliceosomal complex | DNA binding | Homo sapiens | Alternative splicing Coiled coil mRNA processing mRNA splicing Nucleus Phosphoprotein Reference proteome | MAHRPKRTFR | MAHRPKRTFRQRAADSSDSDGAEESPAEPGAPRELPVPGSAEEEPPSGGGRAQVAGLPHRVRGPRGRGRVWASSRRATKAAPRADEGSESRTLDVSTDEEDKIHHSSESKDDQGLSSDSSSSLGEKELSSTVKIPDAAFIQAARRKRELARAQDDYISLDVQHTSSISGMKRESEDDPESEPDDHEKRIPFTLRPQTLRQRMAEESISRNEETSEESQEDEKQDTWEQQQMRKAVKIIEERDIDLSCGNGSSKVKKFDTSISFPPVNLEIIKKQLNTRLTLLQETHRSHLREYEKYVQDVKSSKSTIQNLESSSNQALNCKFYKSMKIYVENLIDCLNEKIINIQEIESSMHALLLKQAMTFMKRRQDELKHESTYLQQLSRKDETSTSGNFSVDEKTQWILEEIESRRTKRRQARVLSGNCNHQEGTSSDDELPSAEMIDFQKSQGDILQKQKKVFEEVQDDFCNIQNILLKFQQWREKFPDSYYEAFISLCIPKLLNPLIRVQLIDWNPLKLESTGLKEMPWFKSVEEFMDSSVEDSKKESSSDKKVLSAIINKTIIPRLTDFVEFLWDPLSTSQTTSLITHCRVILEEHSTCENEVSKSRQDLLKSIVSRMKKAVEDDVFIPLYPKSAVENKTSPHSKFQERQFWSGLKLFRNILLWNGLLTDDTLQELGLGKLLNRYLIIALLNATPGPDVVKKCNQVAACLPEKWFENSAMRTSIPQLENFIQFLLQSAHKLSRSEFRDEVEEIILILVKIKALNQAESFIGEHHLDHLKSLIKED | mRNA splicing, via spliceosome negative regulation of DNA-templated transcription regulation of DNA-templated transcription spliceosomal complex assembly cytosol; nucleolus; nucleoplasm; nucleus; U2-type post-mRNA release spliceosomal complex DNA binding Homo sapiens Alternative splicing Coiled coil mRNA processing mRNA splicing Nucleus Phosphoprotein Reference proteome MAHRPKRTFR MAHRPKRTFRQRAADSSDSDGAEESPAEPGAPRELPVPGSAEEEPPSGGGRAQVAGLPHRVRGPRGRGRVWASSRRATKAAPRADEGSESRTLDVSTDEEDKIHHSSESKDDQGLSSDSSSSLGEKELSSTVKIPDAAFIQAARRKRELARAQDDYISLDVQHTSSISGMKRESEDDPESEPDDHEKRIPFTLRPQTLRQRMAEESISRNEETSEESQEDEKQDTWEQQQMRKAVKIIEERDIDLSCGNGSSKVKKFDTSISFPPVNLEIIKKQLNTRLTLLQETHRSHLREYEKYVQDVKSSKSTIQNLESSSNQALNCKFYKSMKIYVENLIDCLNEKIINIQEIESSMHALLLKQAMTFMKRRQDELKHESTYLQQLSRKDETSTSGNFSVDEKTQWILEEIESRRTKRRQARVLSGNCNHQEGTSSDDELPSAEMIDFQKSQGDILQKQKKVFEEVQDDFCNIQNILLKFQQWREKFPDSYYEAFISLCIPKLLNPLIRVQLIDWNPLKLESTGLKEMPWFKSVEEFMDSSVEDSKKESSSDKKVLSAIINKTIIPRLTDFVEFLWDPLSTSQTTSLITHCRVILEEHSTCENEVSKSRQDLLKSIVSRMKKAVEDDVFIPLYPKSAVENKTSPHSKFQERQFWSGLKLFRNILLWNGLLTDDTLQELGLGKLLNRYLIIALLNATPGPDVVKKCNQVAACLPEKWFENSAMRTSIPQLENFIQFLLQSAHKLSRSEFRDEVEEIILILVKIKALNQAESFIGEHHLDHLKSLIKED |
cholesterol metabolic process diacylglycerol catabolic process ether lipid metabolic process lipid catabolic process termination of RNA polymerase I transcription transcription initiation at RNA polymerase I promoter triglyceride catabolic process | caveola; cytoplasm; cytosol; lipid droplet; membrane; mitochondrion; nucleus | 1,2-diacylglycerol acylhydrolase activity 1,3-diacylglycerol acylhydrolase activity acylglycerol lipase activity all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity hormone-sensitive lipase activity retinyl-palmitate esterase activity rRNA primary transcript binding sterol esterase activity triglyceride lipase activity | Bos taurus | Cell membrane Cholesterol metabolism Cytoplasm Direct protein sequencing Hydrolase Lipid degradation Lipid droplet Lipid metabolism Membrane Phosphoprotein Reference proteome Steroid metabolism Sterol metabolism | MDLRTMTQSL | MDLRTMTQSLVTLAEDNMAFFSSQGPGETARRLTGVFAGIREQALGLEPALGRLLSVAHLFDLDTETPANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLAALTQLRALAYYAQRLLTTNQPGRLFFEGDERVIADFLREYVTLHKGCFYGRCLGFQFTPAIRPFLQTISIGLVSFGEHYKRNETGISVTASSLFTDGRFAIDPELRGAEFERIIQNLDVHFWKAFWNITEIQVLSSLANMASTTVRVSRLLSLPPVAFEMPLTSDPELTVTISPPLAHTGPGPVLVRLISYDLREGQDSKELSSFVRSEGPRSLELRLRPQQAPRSRALVVHIHGGGFVAQTSKSHEPYLKSWAQELGAPILSIDYSLAPEAPFPRALEECFYAYCWAVKHCALLGSTGERICLAGDSAGGNLCFTVSLRAAAYGVRVPDGIMAAYPATMLQSTASPSRLLSLMDHLLPLSVLSKCVSTYAGAETEDHPDSDQKALGVMGLVQRDTALLLRDLRLGASSWLNSFLELGGQKSHLKSVSKTEPMRRSVSEAALTQPEGSLGTDSLKSLKLHDLGLRNSSDTTDTPELSLSAETLGPSAPSTINFLLGSEDGSEMSKAPEELNNKDRVRGVGAAFPEGFHPRRCSQGAMWMPLYSAPIVKNPSMSPLLAPDSMLQTLPPVHIVACALDPMLDDSVMFARRLRGLGQPVTLRVAEDLPHGFLSLAALCRETRQAAALCVERIRLILNLPGPPV | cholesterol metabolic process diacylglycerol catabolic process ether lipid metabolic process lipid catabolic process termination of RNA polymerase I transcription transcription initiation at RNA polymerase I promoter triglyceride catabolic process caveola; cytoplasm; cytosol; lipid droplet; membrane; mitochondrion; nucleus 1,2-diacylglycerol acylhydrolase activity 1,3-diacylglycerol acylhydrolase activity acylglycerol lipase activity all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity hormone-sensitive lipase activity retinyl-palmitate esterase activity rRNA primary transcript binding sterol esterase activity triglyceride lipase activity Bos taurus Cell membrane Cholesterol metabolism Cytoplasm Direct protein sequencing Hydrolase Lipid degradation Lipid droplet Lipid metabolism Membrane Phosphoprotein Reference proteome Steroid metabolism Sterol metabolism MDLRTMTQSL MDLRTMTQSLVTLAEDNMAFFSSQGPGETARRLTGVFAGIREQALGLEPALGRLLSVAHLFDLDTETPANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLAALTQLRALAYYAQRLLTTNQPGRLFFEGDERVIADFLREYVTLHKGCFYGRCLGFQFTPAIRPFLQTISIGLVSFGEHYKRNETGISVTASSLFTDGRFAIDPELRGAEFERIIQNLDVHFWKAFWNITEIQVLSSLANMASTTVRVSRLLSLPPVAFEMPLTSDPELTVTISPPLAHTGPGPVLVRLISYDLREGQDSKELSSFVRSEGPRSLELRLRPQQAPRSRALVVHIHGGGFVAQTSKSHEPYLKSWAQELGAPILSIDYSLAPEAPFPRALEECFYAYCWAVKHCALLGSTGERICLAGDSAGGNLCFTVSLRAAAYGVRVPDGIMAAYPATMLQSTASPSRLLSLMDHLLPLSVLSKCVSTYAGAETEDHPDSDQKALGVMGLVQRDTALLLRDLRLGASSWLNSFLELGGQKSHLKSVSKTEPMRRSVSEAALTQPEGSLGTDSLKSLKLHDLGLRNSSDTTDTPELSLSAETLGPSAPSTINFLLGSEDGSEMSKAPEELNNKDRVRGVGAAFPEGFHPRRCSQGAMWMPLYSAPIVKNPSMSPLLAPDSMLQTLPPVHIVACALDPMLDDSVMFARRLRGLGQPVTLRVAEDLPHGFLSLAALCRETRQAAALCVERIRLILNLPGPPV |
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