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32,911,874
Viruses
Infection of Brain Organoids and 2D Cortical Neurons with SARS-CoV-2 Pseudovirus.
Since the global outbreak of SARS-CoV-2 (COVID-19), infections of diverse human organs along with multiple symptoms continue to be reported. However, the susceptibility of the brain to SARS-CoV-2, and the mechanisms underlying neurological infection are still elusive. Here, we utilized human embryonic stem cell-derived...
ace2;sars-cov-2;brain organoid;cortical neuron;pseudovirus
Journal Article;Research Support, Non-U.S. Gov't
Yi, Sang Ah;Nam, Ki Hong;Yun, Jihye;Gim, Dongmin;Joe, Daeho;Kim, Yong Ho;Kim, Han-Joo;Han, Jeung-Whan;Lee, Jaecheol
10.3390/v12091004
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Infection of Brain Organoids and 2D Cortical Neurons with SARS-CoV-2 Pseudovirus. [Abstract]: Since the global outbreak of SARS-CoV-2 (COVID-19), infections of diverse human organs along with multiple symptoms continue to be reported. However, the susceptibility of the brain to SARS-CoV-2, and the mechanisms u...
32,838,010
Radiol Infect Dis
Changes in CT manifestations and RT-PCR testings of the coronavirus disease 2019 until recovery in patients with afferent infection vs. second-generation infection outside the original city (Wuhan): An observational study.
Objective: To investigate changes in CT manifestations and results of reverse transcription polymerase chain reaction (RT-PCR) testing between afferent and second-generation coronavirus disease 2019 (COVID-19) outside the original city (Wuhan) until recovery. Methods: We collected 26 consecutive COVID-19 patients under...
computed tomography;coronavirus;infection;pneumonia;polymerase chain reaction
Journal Article
Tang, Sun;Ou, Jing;Li, Rui;Zhang, Xiaoming;Chen, Tian-Wu;Li, Hongjun
10.1016/j.jrid.2020.07.007
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Changes in CT manifestations and RT-PCR testings of the coronavirus disease 2019 until recovery in patients with afferent infection vs. second-generation infection outside the original city (Wuhan): An observational study. [Abstract]: Objective: To investigate changes in CT manifestations and results of revers...
32,416,318
Can J Cardiol
Lung Ultrasound for Cardiologists in the Time of COVID-19.
Lung ultrasound (LUS) is a point-of-care ultrasound technique used for its portability, widespread availability, and ability to provide real-time diagnostic information and procedural guidance. LUS outperforms lung auscultation and chest X-ray, and it is an alternative to chest computed tomography in selected cases. Ca...
Journal Article
Kiamanesh, Omid;Harper, Lea;Wiskar, Katie;Luksun, Warren;McDonald, Michael;Ross, Heather;Woo, Anna;Granton, John
10.1016/j.cjca.2020.05.008
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Lung Ultrasound for Cardiologists in the Time of COVID-19. [Abstract]: Lung ultrasound (LUS) is a point-of-care ultrasound technique used for its portability, widespread availability, and ability to provide real-time diagnostic information and procedural guidance. LUS outperforms lung auscultation and chest X-...
33,080,471
Int J Pediatr Otorhinolaryngol
Rapid telemedicine implementation in the context of the COVID-19 pandemic in an academic pediatric otolaryngology practice.
OBJECTIVE: To describe the implementation of telemedicine in a pediatric otolaryngology practice during the coronavirus disease 2019 (COVID-19) global pandemic. METHODS: A descriptive paper documenting the development and application of telemedicine in a tertiary academic pediatric otolaryngology practice. RESULTS: A t...
covid-19;healthcare access;pediatric otolaryngology;telemedicine
Journal Article
Govil, Nandini;Raol, Nikhila;Tey, Ching Siong;Goudy, Steven L;Alfonso, Kristan P
10.1016/j.ijporl.2020.110447
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Rapid telemedicine implementation in the context of the COVID-19 pandemic in an academic pediatric otolaryngology practice. [Abstract]: OBJECTIVE: To describe the implementation of telemedicine in a pediatric otolaryngology practice during the coronavirus disease 2019 (COVID-19) global pandemic. METHODS: A des...
32,899,009
Medicine (Baltimore)
Analysis of type I IFN response and T cell activation in severe COVID-19/HIV-1 coinfection: A case report.
RATIONALE: Complex immune dysregulation in interferon (IFN) and T cell response has been observed in human immunodeficiency virus (HIV-1)-infected patients as well as in coronavirus disease-2019 (COVID-19) patients. However, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)/HIV-1 coinfection has been describ...
Journal Article
d'Ettorre, Gabriella;Recchia, Gregorio;Ridolfi, Marco;Siccardi, Guido;Pinacchio, Claudia;Innocenti, Giuseppe Pietro;Santinelli, Letizia;Frasca, Federica;Bitossi, Camilla;Ceccarelli, Giancarlo;Borrazzo, Cristian;Antonelli, Guido;Scagnolari, Carolina;Mastroianni, Claudio Maria
10.1097/MD.0000000000021803
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Analysis of type I IFN response and T cell activation in severe COVID-19/HIV-1 coinfection: A case report. [Abstract]: RATIONALE: Complex immune dysregulation in interferon (IFN) and T cell response has been observed in human immunodeficiency virus (HIV-1)-infected patients as well as in coronavirus disease-20...
32,363,409
Environ Monit Assess
SARS-CoV-2 spread in Northern Italy: what about the pollution role?
The recent epidemic of the new SARS-CoV-2 in the northern regions of Italy is putting the organization of the Italian health system under serious attack. The current emergency requires all possible efforts to stem the spread of the virus. In this context, it is clear that we have the urgent need to rely upon etiopathog...
covid-19;pm-10;pm-2.5;pollution;sars-cov-2
Journal Article
Sciomer, Susanna;Moscucci, Federica;Magri, Damiano;Badagliacca, Roberto;Piccirillo, Gianfranco;Agostoni, Piergiuseppe
10.1007/s10661-020-08317-y
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: SARS-CoV-2 spread in Northern Italy: what about the pollution role? [Abstract]: The recent epidemic of the new SARS-CoV-2 in the northern regions of Italy is putting the organization of the Italian health system under serious attack. The current emergency requires all possible efforts to stem the spread of the...
32,755,114
Tuberk Toraks
Asthma and COVID-19: What do we know?
There are limited data about the coexistence of asthma and the Coronavirus disease-2019 (COVID-19). The COVID-19 pandemic is a new disease for the whole world. In this study, we aimed to examine the published case series with the COVID-19 and asthma coexistence, by reviewing existing studies and other publications. We ...
Journal Article;Review
Sarioglu, Nurhan
10.5578/tt.69775
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Asthma and COVID-19: What do we know? [Abstract]: There are limited data about the coexistence of asthma and the Coronavirus disease-2019 (COVID-19). The COVID-19 pandemic is a new disease for the whole world. In this study, we aimed to examine the published case series with the COVID-19 and asthma coexistence...
32,621,718
Curr Top Med Chem
Shape-based Machine Learning Models for the Potential Novel COVID-19 Protease Inhibitors Assisted by Molecular Dynamics Simulation.
BACKGROUND: The vast geographical expansion of novel coronavirus and an increasing number of COVID-19 affected cases have overwhelmed health and public health services. Artificial Intelligence (AI) and Machine Learning (ML) algorithms have extended their major role in tracking disease patterns, and in identifying possi...
covid-19;covid-19 protease inhibitors;machine learning;molecular dynamics simulation;molecular docking;remdesivir;shape-based ml;ncorv-embs
Journal Article
Nayarisseri, Anuraj;Khandelwal, Ravina;Madhavi, Maddala;Selvaraj, Chandrabose;Panwar, Umesh;Sharma, Khushboo;Hussain, Tajamul;Singh, Sanjeev Kumar
10.2174/1568026620666200704135327
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Shape-based Machine Learning Models for the Potential Novel COVID-19 Protease Inhibitors Assisted by Molecular Dynamics Simulation. [Abstract]: BACKGROUND: The vast geographical expansion of novel coronavirus and an increasing number of COVID-19 affected cases have overwhelmed health and public health services...
32,773,853
Indian J Anaesth
Effectiveness of simulation based teaching of ventilatory management among non-anaesthesiology residents to manage COVID 19 pandemic - A Quasi experimental cross sectional pilot study.
Background and Aims: Simulation is one of the important learning tools when it comes to skill acquisition and as a supplemental tool for training in high stake situations like COVID-19. The aim of this study is to meet the global requirements of knowledge on ventilatory management, prepare and to evaluate the effective...
covid 19;feedback;mechanical ventilation;pandemic;training support
Journal Article
Mouli, Tatikonda Chandra;Davuluri, Anjani;Vijaya, Sana;Priyanka, Avala Devi Yamini;Mishra, Sushant Kumar
10.4103/ija.IJA_452_20
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Effectiveness of simulation based teaching of ventilatory management among non-anaesthesiology residents to manage COVID 19 pandemic - A Quasi experimental cross sectional pilot study. [Abstract]: Background and Aims: Simulation is one of the important learning tools when it comes to skill acquisition and as a...
32,498,136
J Prev Med Public Health
Estimate of the Basic Reproduction Number for COVID-19: A Systematic Review and Meta-analysis.
OBJECTIVES: The outbreak of coronavirus disease 2019 (COVID-19) is one of the main public health challenges currently facing the world. Because of its high transmissibility, COVID-19 has already caused extensive morbidity and mortality in many countries throughout the world. An accurate estimation of the basic reproduc...
basic reproduction number;covid-19;meta-analysis;outbreak;public health
Journal Article;Meta-Analysis;Systematic Review
Alimohamadi, Yousef;Taghdir, Maryam;Sepandi, Mojtaba
10.3961/jpmph.20.076
[ 0, 0, 0, 0, 0, 1, 0 ]
[Title]: Estimate of the Basic Reproduction Number for COVID-19: A Systematic Review and Meta-analysis. [Abstract]: OBJECTIVES: The outbreak of coronavirus disease 2019 (COVID-19) is one of the main public health challenges currently facing the world. Because of its high transmissibility, COVID-19 has already caused ex...
32,898,715
Clin Microbiol Infect
The kinetics of viral load and antibodies to SARS-CoV-2.
OBJECTIVES: The aim was to understand persistence of the virus in body fluids the and immune response of an infected host to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), an agent of coronavirus disease 2019 (COVID-19). METHODS: We determined the kinetics of viral load in several body fluids through rea...
covid-19;iga;igg;igm;neutralizing antibodies;sars-cov-2;viral load
Journal Article
Sun, Jiufeng;Tang, Xi;Bai, Ru;Liang, Chumin;Zeng, Lilian;Lin, Huifang;Yuan, Runyu;Zhou, Pingping;Huang, Xuhe;Xiong, Qianlin;Peng, Jinju;Cui, Fengfu;Ke, Bixia;Su, Juan;Liu, Zhe;Lu, Jing;Tian, Junzhang;Sun, Ruilin;Ke, Changwen
10.1016/j.cmi.2020.08.043
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: The kinetics of viral load and antibodies to SARS-CoV-2. [Abstract]: OBJECTIVES: The aim was to understand persistence of the virus in body fluids the and immune response of an infected host to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), an agent of coronavirus disease 2019 (COVID-19). METHOD...
32,846,167
Life Sci
Correlation of D-xylose with severity and morbidity-related factors of COVID-19 and possible therapeutic use of D-xylose and antibiotics for COVID-19.
The SARS-Cov-2 pandemic that currently affects the entire world has been shown to be especially dangerous in the elderly (>/=65 years) and in smokers, with notably strong comorbidity in patients already suffering from chronic diseases, such as Type 2 diabetes, cancers, chronic respiratory diseases, obesity, and hyperte...
acute kidney injury;diabetes;inflammatory;lung;scurvy;xylitol, sars-cov-2;xylose
Journal Article;Review
Cheudjeu, Antony
10.1016/j.lfs.2020.118335
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Correlation of D-xylose with severity and morbidity-related factors of COVID-19 and possible therapeutic use of D-xylose and antibiotics for COVID-19. [Abstract]: The SARS-Cov-2 pandemic that currently affects the entire world has been shown to be especially dangerous in the elderly (>/=65 years) and in smoker...
32,903,058
AJR Am J Roentgenol
COVID-19-Related Disseminated Leukoencephalopathy (CRDL): A Retrospective Study of Findings on Brain MRI.
Among 2,820 inpatients with coronavirus disease-2019 (COVID-19), 59 (2.1%) underwent brain MRI. Of these patients, six (10.2%) had findings on MRI suspicious for COVID-19 related disseminated leukoencephalopathy (CRDL), characterized by extensive confluent or multifocal white matter lesions (with characteristics and lo...
Journal Article
Freeman, Colbey W;Masur, Jonathan;Hassankhani, Alvand;Wolf, Ronald L;Levine, Joshua M;Mohan, Suyash
10.2214/AJR.20.24364
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: COVID-19-Related Disseminated Leukoencephalopathy (CRDL): A Retrospective Study of Findings on Brain MRI. [Abstract]: Among 2,820 inpatients with coronavirus disease-2019 (COVID-19), 59 (2.1%) underwent brain MRI. Of these patients, six (10.2%) had findings on MRI suspicious for COVID-19 related disseminated l...
32,905,028
Zentralbl Arbeitsmed Arbeitsschutz Ergon
[Recommended actions: Reinforcing clinicians' resilience and supporting second victims during the COVID-19 pandemic to maintain capacity in the healthcare system].
The term second victim describes a person involved in patient care who, due to an extraordinary patient care situation, also becomes traumatized. This phenomenon is largely unknown to the general public, although it is widespread, and is being exacerbated by the COVID-19 pandemic. Pronounced psychological strain among ...
communication;leadership;patient care;patient safety;psychological strain
English Abstract;Journal Article;Review
Strametz, R;Raspe, M;Ettl, B;Huf, W;Pitz, A
10.1007/s40664-020-00405-7
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [Recommended actions: Reinforcing clinicians' resilience and supporting second victims during the COVID-19 pandemic to maintain capacity in the healthcare system]. [Abstract]: The term second victim describes a person involved in patient care who, due to an extraordinary patient care situation, also becomes tr...
33,035,175
J Med Internet Res
Prognostic Assessment of COVID-19 in the Intensive Care Unit by Machine Learning Methods: Model Development and Validation.
BACKGROUND: Patients with COVID-19 in the intensive care unit (ICU) have a high mortality rate, and methods to assess patients' prognosis early and administer precise treatment are of great significance. OBJECTIVE: The aim of this study was to use machine learning to construct a model for the analysis of risk factors a...
covid-19;icu;lime;shap;death prediction model;factor analysis;machine learning
Journal Article
Pan, Pan;Li, Yichao;Xiao, Yongjiu;Han, Bingchao;Su, Longxiang;Su, Mingliang;Li, Yansheng;Zhang, Siqi;Jiang, Dapeng;Chen, Xia;Zhou, Fuquan;Ma, Ling;Bao, Pengtao;Xie, Lixin
10.2196/23128
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Prognostic Assessment of COVID-19 in the Intensive Care Unit by Machine Learning Methods: Model Development and Validation. [Abstract]: BACKGROUND: Patients with COVID-19 in the intensive care unit (ICU) have a high mortality rate, and methods to assess patients' prognosis early and administer precise treatmen...
32,528,194
Sudan J Paediatr
Perspectives on repositioning chloroquine and hydroxychloroquine for the treatment of Covid-19.
Coronavirus disease 2019 (COVID-19) is now spreading as a pandemic ravaging the whole world. In the absence of a vaccine and an effective antiviral chemotherapy, there is currently an intense global interest in repositioning chloroquine (CQ) and its derivative hydroxychloroquine (HCQ) to combat the pandemic. CQ has bee...
covid-19;chloroquine;coronavirus disease 2019;hydroxychloroquine;malaria;prophylaxis;treatment
Journal Article
Adeel, Ahmed Awad
10.24911/SJP.106-1587122398
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Perspectives on repositioning chloroquine and hydroxychloroquine for the treatment of Covid-19. [Abstract]: Coronavirus disease 2019 (COVID-19) is now spreading as a pandemic ravaging the whole world. In the absence of a vaccine and an effective antiviral chemotherapy, there is currently an intense global inte...
32,797,094
PLoS One
Containment of a healthcare-associated COVID-19 outbreak in a university hospital in Seoul, Korea: A single-center experience.
BACKGROUND: Our hospital experienced the first healthcare-associated COVID-19 outbreak in Seoul at the time the first COVID-19 cases were confirmed in Korea. The first confirmed COVID-19 patient was a hospital personnel who was in charge of transferring patients inside our hospital. To contain the virus spread, we shut...
Case Reports;Journal Article
Kim, Sei Won;Jo, Sung Jin;Lee, Heayon;Oh, Jung Hwan;Lim, Jihyang;Lee, Sang Haak;Choi, Jung Hyun;Lee, Jehoon
10.1371/journal.pone.0237692
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Containment of a healthcare-associated COVID-19 outbreak in a university hospital in Seoul, Korea: A single-center experience. [Abstract]: BACKGROUND: Our hospital experienced the first healthcare-associated COVID-19 outbreak in Seoul at the time the first COVID-19 cases were confirmed in Korea. The first conf...
32,965,661
Oncology (Williston Park)
Delay in Cancer Screening and Diagnosis During the COVID-19 Pandemic: What Is the Cost?
During the height of the coronavirus disease 2019(COVID-19) pandemic, many health care facilities needed to focus on screening for and treating patients with known or suspected COVID-19. This resulted in the diversion of health care workers and resources.
Journal Article
Vose, Julie M
10.46883/ONC.2020.3409.0343
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Delay in Cancer Screening and Diagnosis During the COVID-19 Pandemic: What Is the Cost? [Abstract]: During the height of the coronavirus disease 2019(COVID-19) pandemic, many health care facilities needed to focus on screening for and treating patients with known or suspected COVID-19. This resulted in the div...
32,863,869
Ecancermedicalscience
Good clinical practice advice for the management of patients with gynaecological cancer during the COVID-19 pandemic in Nigeria and other resource-constrained countries.
The impact of the COVID-19 pandemic on healthcare services in settings with under-resourced health systems such as that of Nigeria is likely to be substantial in the coming months. The gynaecological oncology services still need to be prioritised as an essential core health service. There are increasing concerns from b...
covid-19;nigeria;cancer treatment;coronavirus;gynaecological oncology
Journal Article;Review
Okunade, Kehinde S;Okunowo, Adeyemi A;Ohazurike, Ephraim O;Anorlu, Rose I
10.3332/ecancer.2020.1075
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Good clinical practice advice for the management of patients with gynaecological cancer during the COVID-19 pandemic in Nigeria and other resource-constrained countries. [Abstract]: The impact of the COVID-19 pandemic on healthcare services in settings with under-resourced health systems such as that of Nigeri...
32,950,458
Braz J Infect Dis
SARS-CoV-2 viremia may predict rapid deterioration of COVID-19 patients.
COVID-19 has raised worldwide concern as spiraling into a pandemic. Reports about comprehensive investigation of COVID-19 viremia are extremely scanty. Herein, we present four COVID-19 patients with positive SARS-CoV-2 nucleic acid test in blood, accounting for 12.12% of 33 detected cases. Rapid deterioration of these ...
deterioration;predict;sars-cov-2;viremia
Journal Article
Tan, Cuiyan;Li, Songbiao;Liang, Yingjian;Chen, Meizhu;Liu, Jing
10.1016/j.bjid.2020.08.010
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: SARS-CoV-2 viremia may predict rapid deterioration of COVID-19 patients. [Abstract]: COVID-19 has raised worldwide concern as spiraling into a pandemic. Reports about comprehensive investigation of COVID-19 viremia are extremely scanty. Herein, we present four COVID-19 patients with positive SARS-CoV-2 nucleic...
32,837,764
Chronic Dis Transl Med
2019 novel-coronavirus: Cardiovascular insights about risk factors, myocardial injury, therapy and clinical implications.
From December 31st, 2019, a novel highly pathogenic coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread worldwide, reaching at present the dimension of a pandemic. In addition to damaging the lungs, SARS-CoV-2 may also damage the heart and this is corroborated by the evidence that card...
angiotensin converting enzyme 2;angiotensin converting enzyme inhibitors;angiotensin-ii receptor blockers;covid-19;cardiovascular
Journal Article;Review
Cappannoli, Luigi;Scacciavillani, Roberto;Iannaccone, Giulia;Anastasia, Gianluca;Di Giusto, Federico;Loria, Valentina;Aspromonte, Nadia
10.1016/j.cdtm.2020.06.002
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: 2019 novel-coronavirus: Cardiovascular insights about risk factors, myocardial injury, therapy and clinical implications. [Abstract]: From December 31st, 2019, a novel highly pathogenic coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread worldwide, reaching at present the dime...
32,538,659
Psychol Trauma
The coronavirus pandemic and Holocaust survivors in Israel.
Holocaust survivors in Israel and abroad appear to be especially vulnerable to COVID-19 because of their early life history, advanced age, and associated health conditions. And although some survivors may experience retraumatization because of the pandemic, others appear to be especially resilient. We encourage a stren...
Journal Article
Cohn-Schwartz, Ella;Sagi, Doron;O'Rourke, Norm;Bachner, Yaacov G
10.1037/tra0000771
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The coronavirus pandemic and Holocaust survivors in Israel. [Abstract]: Holocaust survivors in Israel and abroad appear to be especially vulnerable to COVID-19 because of their early life history, advanced age, and associated health conditions. And although some survivors may experience retraumatization becaus...
33,003,964
Circ Arrhythm Electrophysiol
Safely Administering Potential QTc Prolonging Therapy Across a Large Health Care System in the COVID-19 Era.
BACKGROUND: The severe acute respiratory syndrome coronavirus 2 (SARs-CoV-2) has resulted in a global pandemic. Hydroxychloroquine+/-azithromycin have been widely used to treat coronavirus disease 2019 (COVID-19) despite a paucity of evidence regarding efficacy. The incidence of torsade de pointes remains unknown. Wide...
covid-19;azithromycin;hydroxychloroquine;pandemic;torsade de pointes
Journal Article;Multicenter Study
Saleh, Moussa;Gabriels, James;Chang, David;Fishbein, Joanna;Qiu, Michael;Mountantonakis, Stavros E;Epstein, Laurence M
10.1161/CIRCEP.120.008937
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Safely Administering Potential QTc Prolonging Therapy Across a Large Health Care System in the COVID-19 Era. [Abstract]: BACKGROUND: The severe acute respiratory syndrome coronavirus 2 (SARs-CoV-2) has resulted in a global pandemic. Hydroxychloroquine+/-azithromycin have been widely used to treat coronavirus d...
32,869,938
Dermatol Ther
Relative changes in the pattern of diseases presenting in dermatology outpatient clinic in the era of the COVID-19 pandemic.
As an increasing number of COVID-19 cases, there were changes in the number of patients who attended the dermatology outpatient clinics. We aimed to investigate the change profiles of dermatologic diseases in the first and second months of the COVID-19 pandemic in Turkey by comparing with the corresponding period of th...
covid-19;dermatology;outpatient clinic
Comparative Study;Journal Article
Kutlu, Omer;Metin, Ahmet
10.1111/dth.14096
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Relative changes in the pattern of diseases presenting in dermatology outpatient clinic in the era of the COVID-19 pandemic. [Abstract]: As an increasing number of COVID-19 cases, there were changes in the number of patients who attended the dermatology outpatient clinics. We aimed to investigate the change pr...
32,789,838
Cardiol J
Immersive technologies as a solution for general data protection regulation in Europe and impact on the COVID-19 pandemic.
BACKGROUND: General data protection regulation (GDPR) provides rules according to which data should be managed and processed in a secure and appropriate way for patient requirements and security. Currently, everyone in Europe is covered by GDPR. Thus, the medical practice also requires access to patient data in a safe ...
augmented reality;mixed reality;pandemic
Journal Article;Research Support, Non-U.S. Gov't
Proniewska, Klaudia;Pregowska, Agnieszka;Dolega-Dolegowski, Damian;Dudek, Dariusz
10.5603/CJ.a2020.0102
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Immersive technologies as a solution for general data protection regulation in Europe and impact on the COVID-19 pandemic. [Abstract]: BACKGROUND: General data protection regulation (GDPR) provides rules according to which data should be managed and processed in a secure and appropriate way for patient require...
32,329,926
Head Neck
Tracheostomy guidelines developed at a large academic medical center during the COVID-19 pandemic.
BACKGROUND: During the SARS-CoV-2 pandemic, tracheostomy may be required for COVID-19 patients requiring long-term ventilation in addition to other conditions such as airway compromise from head and neck cancer. As an aerosol-generating procedure, tracheostomy increases the exposure of health care workers to COVID-19 i...
covid-19;coronavirus;personal protective equipment (ppe);tracheostomy;tracheotomy
Journal Article
David, Abel P;Russell, Marika D;El-Sayed, Ivan H;Russell, Matthew S
10.1002/hed.26191
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Tracheostomy guidelines developed at a large academic medical center during the COVID-19 pandemic. [Abstract]: BACKGROUND: During the SARS-CoV-2 pandemic, tracheostomy may be required for COVID-19 patients requiring long-term ventilation in addition to other conditions such as airway compromise from head and n...
32,725,247
JAMA Netw Open
Comparison of Face-Touching Behaviors Before and During the Coronavirus Disease 2019 Pandemic.
Importance: There is insufficient evidence on the efficacy of masks in the general population for the prevention of coronavirus disease 2019 (COVID-19) in public areas. Therefore, it is imperative to investigate the association of mandatory mask-wearing policies with behaviors associated with the transmission of COVID-...
Comparative Study;Journal Article;Research Support, Non-U.S. Gov't
Chen, Yong-Jian;Qin, Gang;Chen, Jie;Xu, Jian-Liang;Feng, Ding-Yun;Wu, Xiang-Yuan;Li, Xing
10.1001/jamanetworkopen.2020.16924
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Comparison of Face-Touching Behaviors Before and During the Coronavirus Disease 2019 Pandemic. [Abstract]: Importance: There is insufficient evidence on the efficacy of masks in the general population for the prevention of coronavirus disease 2019 (COVID-19) in public areas. Therefore, it is imperative to inve...
32,405,081
Clin Radiol
Point-of-care lung ultrasound in intensive care during the COVID-19 pandemic.
Coronavirus disease 2019 has spread to every inhabited continent in the world. So far, plain radiography and computed tomography have been the mainstay of imaging methods used. The present analytical paper on the role of point-of-care lung ultrasound in this pandemic examines its diagnostic accuracy, clinical utility, ...
Journal Article;Review
Kulkarni, S;Down, B;Jha, S
10.1016/j.crad.2020.05.001
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Point-of-care lung ultrasound in intensive care during the COVID-19 pandemic. [Abstract]: Coronavirus disease 2019 has spread to every inhabited continent in the world. So far, plain radiography and computed tomography have been the mainstay of imaging methods used. The present analytical paper on the role of ...
32,542,847
Vox Sang
Clinical use of Convalescent Plasma in the COVID-19 pandemic: a transfusion-focussed gap analysis with recommendations for future research priorities.
BACKGROUND AND OBJECTIVES: Use of convalescent plasma for coronavirus disease 2019 (COVID-19) treatment has gained interest worldwide. However, there is lack of evidence on its dosing, safety and effectiveness. Until data from clinical studies are available to provide solid evidence for worldwide applicable guidelines,...
covid-19;sars-cov-2;convalescent plasma;gap analysis;patient outcome
Journal Article
Al-Riyami, Arwa Z;Schafer, Richard;van den Berg, Karin;Bloch, Evan M;Estcourt, Lise J;Goel, Ruchika;Hindawi, Salwa;Josephson, Cassandra D;Land, Kevin;McQuilten, Zoe K;Spitalnik, Steven L;Wood, Erica M;Devine, Dana V;So-Osman, Cynthia
10.1111/vox.12973
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Clinical use of Convalescent Plasma in the COVID-19 pandemic: a transfusion-focussed gap analysis with recommendations for future research priorities. [Abstract]: BACKGROUND AND OBJECTIVES: Use of convalescent plasma for coronavirus disease 2019 (COVID-19) treatment has gained interest worldwide. However, ther...
32,341,627
Chaos Solitons Fractals
Estimating the infection horizon of COVID-19 in eight countries with a data-driven approach.
The COVID-19 pandemic has affected all countries of the world producing a substantial number of fatalities accompanied by a major disruption in their social, financial and educational organization. The strict disciplinary measures implemented by China were very effective and thus were subsequently adopted by most world...
covid-19;data-driven;imposed measures;infection horizon
Journal Article
Barmparis, G D;Tsironis, G P
10.1016/j.chaos.2020.109842
[ 0, 0, 0, 0, 0, 1, 0 ]
[Title]: Estimating the infection horizon of COVID-19 in eight countries with a data-driven approach. [Abstract]: The COVID-19 pandemic has affected all countries of the world producing a substantial number of fatalities accompanied by a major disruption in their social, financial and educational organization. The stri...
32,975,574
JAMA Netw Open
Association of Race and Ethnicity With Comorbidities and Survival Among Patients With COVID-19 at an Urban Medical Center in New York.
Importance: As of May 11, 2020, there have been more than 290000 deaths worldwide from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19). Risk-adjusted differences in outcomes among patients of differing ethnicity and race categories are not well characterize...
Journal Article
Kabarriti, Rafi;Brodin, N Patrik;Maron, Maxim I;Guha, Chandan;Kalnicki, Shalom;Garg, Madhur K;Racine, Andrew D
10.1001/jamanetworkopen.2020.19795
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Association of Race and Ethnicity With Comorbidities and Survival Among Patients With COVID-19 at an Urban Medical Center in New York. [Abstract]: Importance: As of May 11, 2020, there have been more than 290000 deaths worldwide from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes co...
32,853,982
Thromb Res
Admission D-dimer levels, D-dimer trends, and outcomes in COVID-19.
Observational data suggest an acquired prothrombotic state may contribute to the pathophysiology of COVID-19. These data include elevated D-dimers observed among many COVID-19 patients. We present a retrospective analysis of admission D-dimer, and D-dimer trends, among 1065 adult hospitalized COVID-19 patients, across ...
admission;covid-19;d-dimer;outcomes;thrombosis;trend
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Naymagon, Leonard;Zubizarreta, Nicole;Feld, Jonathan;van Gerwen, Maaike;Alsen, Mathilda;Thibaud, Santiago;Kessler, Alaina;Venugopal, Sangeetha;Makki, Iman;Qin, Qian;Dharmapuri, Sirish;Jun, Tomi;Bhalla, Sheena;Berwick, Shana;Christian, Krina;Mascarenhas, John;Dembitzer, Francine;Moshier, Erin;Tremblay, Douglas
10.1016/j.thromres.2020.08.032
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Admission D-dimer levels, D-dimer trends, and outcomes in COVID-19. [Abstract]: Observational data suggest an acquired prothrombotic state may contribute to the pathophysiology of COVID-19. These data include elevated D-dimers observed among many COVID-19 patients. We present a retrospective analysis of admiss...
32,276,755
Acad Radiol
Infection Control against COVID-19 in Departments of Radiology.
The COVID-19 epidemic, which is caused by the novel coronavirus SARS-CoV-2, has spread rapidly to become a world-wide pandemic. Chest radiography and chest CT are frequently used to support the diagnosis of COVID-19 infection. However, multiple cases of COVID-19 transmission in radiology department have been reported. ...
covid-19;infection control;radiology department;sars-cov-2
Journal Article
Yu, Juan;Ding, Ning;Chen, Huan;Liu, Xia-Jing;He, Wen-Jie;Dai, Wei-Cai;Zhou, Zhao-Guang;Lin, Fan;Pu, Zu-Hui;Li, Ding-Fu;Xu, Hua-Jian;Wang, Yu-Li;Zhang, Han-Wen;Lei, Yi
10.1016/j.acra.2020.03.025
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Infection Control against COVID-19 in Departments of Radiology. [Abstract]: The COVID-19 epidemic, which is caused by the novel coronavirus SARS-CoV-2, has spread rapidly to become a world-wide pandemic. Chest radiography and chest CT are frequently used to support the diagnosis of COVID-19 infection. However,...
32,917,809
Neurology
Loss of smell in patients with COVID-19: MRI data reveal a transient edema of the olfactory clefts.
OBJECTIVE: To assess the physiopathology of olfactory function loss (OFL) in patients with coronavirus disease 2019 (COVID-19), we evaluated the olfactory clefts (OC) on MRI during the early stage of the disease and 1 month later. METHODS: This was a prospective, monocentric, case-controlled study. Twenty severe acute ...
Journal Article
Eliezer, Michael;Hamel, Anne-Laurel;Houdart, Emmanuel;Herman, Philippe;Housset, Juliette;Jourdaine, Clement;Eloit, Corinne;Verillaud, Benjamin;Hautefort, Charlotte
10.1212/WNL.0000000000010806
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Loss of smell in patients with COVID-19: MRI data reveal a transient edema of the olfactory clefts. [Abstract]: OBJECTIVE: To assess the physiopathology of olfactory function loss (OFL) in patients with coronavirus disease 2019 (COVID-19), we evaluated the olfactory clefts (OC) on MRI during the early stage of...
32,697,943
Cell Metab
Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1alpha/Glycolysis-Dependent Axis.
COVID-19 can result in severe lung injury. It remained to be determined why diabetic individuals with uncontrolled glucose levels are more prone to develop the severe form of COVID-19. The molecular mechanism underlying SARS-CoV-2 infection and what determines the onset of the cytokine storm found in severe COVID-19 pa...
covid-19;hif-1alpha;sars-cov-2;diabetes;glycolysis;inflammation;interferon;metabolism;mitochondria;monocyte
Journal Article;Research Support, Non-U.S. Gov't
Codo, Ana Campos;Davanzo, Gustavo Gastao;Monteiro, Lauar de Brito;de Souza, Gabriela Fabiano;Muraro, Stefanie Primon;Virgilio-da-Silva, Joao Victor;Prodonoff, Juliana Silveira;Carregari, Victor Corasolla;de Biagi Junior, Carlos Alberto Oliveira;Crunfli, Fernanda;Jimenez Restrepo, Jeffersson Leandro;Vendramini, Pedro He...
10.1016/j.cmet.2020.07.007
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1alpha/Glycolysis-Dependent Axis. [Abstract]: COVID-19 can result in severe lung injury. It remained to be determined why diabetic individuals with uncontrolled glucose levels are more prone to develop the severe form of COV...
32,501,806
JMIR Public Health Surveill
Fluctuation of Public Interest in COVID-19 in the United States: Retrospective Analysis of Google Trends Search Data.
BACKGROUND: In the absence of vaccines and established treatments, nonpharmaceutical interventions (NPIs) are fundamental tools to control coronavirus disease (COVID-19) transmission. NPIs require public interest to be successful. In the United States, there is a lack of published research on the factors that influence...
covid-19;google trends;infodemiology;sars-cov-2;digital health;internet;public health;trend
Journal Article
Husain, Iltifat;Briggs, Blake;Lefebvre, Cedric;Cline, David M;Stopyra, Jason P;O'Brien, Mary Claire;Vaithi, Ramupriya;Gilmore, Scott;Countryman, Chase
10.2196/19969
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Fluctuation of Public Interest in COVID-19 in the United States: Retrospective Analysis of Google Trends Search Data. [Abstract]: BACKGROUND: In the absence of vaccines and established treatments, nonpharmaceutical interventions (NPIs) are fundamental tools to control coronavirus disease (COVID-19) transmissio...
33,065,278
J Steroid Biochem Mol Biol
Coronavirus Disease 2019 (SARS-CoV-2) and polycystic ovarian disease: Is there a higher risk for these women?
The new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been associated with acute respiratory distress syndrome and infected patients have a relatively high risk of death. Emerging risk factors for poor outcome in this disease include age, male gender, cardiovascular co-morbidities including hypertens...
hyperandrogenism;insulin resistance;polycystic ovarian disease;polycystic ovarian syndrome;sars-cov-2
Journal Article;Review
Morgante, Giuseppe;Troia, Libera;De Leo, Vincenzo
10.1016/j.jsbmb.2020.105770
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Coronavirus Disease 2019 (SARS-CoV-2) and polycystic ovarian disease: Is there a higher risk for these women? [Abstract]: The new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been associated with acute respiratory distress syndrome and infected patients have a relatively high risk of death....
32,860,226
Mov Disord
The Impact of COVID-19 on Access to Parkinson's Disease Medication.
BACKGROUND: Many countries have implemented drastic measures to fight the COVID-19 pandemic. Restrictions and diversion of resources may have negatively affected patients with Parkinson's disease (PD). Our aim was to examine whether COVID-19 had an impact on access to PD medication by region and income. METHODS: This s...
parkinson's disease; covid-19; epidemiology; access; medication
Journal Article;Research Support, Non-U.S. Gov't
Cheong, Julia Ling-Yu;Goh, Zhao Hang Keith;Marras, Connie;Tanner, Caroline M;Kasten, Meike;Noyce, Alastair J
10.1002/mds.28293
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The Impact of COVID-19 on Access to Parkinson's Disease Medication. [Abstract]: BACKGROUND: Many countries have implemented drastic measures to fight the COVID-19 pandemic. Restrictions and diversion of resources may have negatively affected patients with Parkinson's disease (PD). Our aim was to examine whethe...
32,789,951
Alzheimers Dement
Tackling challenges in care of Alzheimer's disease and other dementias amid the COVID-19 pandemic, now and in the future.
We have provided an overview on the profound impact of COVID-19 upon older people with Alzheimer's disease and other dementias and the challenges encountered in our management of dementia in different health-care settings, including hospital, out-patient, care homes, and the community during the COVID-19 pandemic. We h...
alzheimer's disease;covid-19;dementia;older people
Journal Article;Review
Mok, Vincent C T;Pendlebury, Sarah;Wong, Adrian;Alladi, Suvarna;Au, Lisa;Bath, Philip M;Biessels, Geert Jan;Chen, Christopher;Cordonnier, Charlotte;Dichgans, Martin;Dominguez, Jacqueline;Gorelick, Philip B;Kim, SangYun;Kwok, Timothy;Greenberg, Steven M;Jia, Jianping;Kalaria, Rajesh;Kivipelto, Miia;Naegandran, Kandiah;L...
10.1002/alz.12143
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Tackling challenges in care of Alzheimer's disease and other dementias amid the COVID-19 pandemic, now and in the future. [Abstract]: We have provided an overview on the profound impact of COVID-19 upon older people with Alzheimer's disease and other dementias and the challenges encountered in our management o...
32,746,851
Int J Equity Health
Disability inclusiveness of government responses to COVID-19 in South America: a framework analysis study.
BACKGROUND: Disabled people are particularly exposed to the risks of COVID-19, as well as to the measures taken to address it, and their impact. The aim of the study was to examine the disability-inclusiveness of government responses to COVID-19 in four South American Countries: Argentina, Brazil, Chile, and Peru. METH...
covid-19;convention on the rights of persons with disabilities;disabled people;government response;inclusiveness;south america
Journal Article
Sakellariou, Dikaios;Malfitano, Ana Paula Serrata;Rotarou, Elena S
10.1186/s12939-020-01244-x
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Disability inclusiveness of government responses to COVID-19 in South America: a framework analysis study. [Abstract]: BACKGROUND: Disabled people are particularly exposed to the risks of COVID-19, as well as to the measures taken to address it, and their impact. The aim of the study was to examine the disabil...
32,333,601
Inflamm Bowel Dis
Expression of SARS-CoV-2 Entry Molecules ACE2 and TMPRSS2 in the Gut of Patients With IBD.
BACKGROUND: Patients with inflammatory bowel disease (IBD) have intestinal inflammation and are treated with immune-modulating medications. In the face of the coronavirus disease-19 pandemic, we do not know whether patients with IBD will be more susceptible to infection or disease. We hypothesized that the viral entry ...
crohn disease;coronavirus;ulcerative colitis
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Burgueno, Juan F;Reich, Adrian;Hazime, Hajar;Quintero, Maria A;Fernandez, Irina;Fritsch, Julia;Santander, Ana M;Brito, Nivis;Damas, Oriana M;Deshpande, Amar;Kerman, David H;Zhang, Lanyu;Gao, Zhen;Ban, Yuguang;Wang, Lily;Pignac-Kobinger, Judith;Abreu, Maria T
10.1093/ibd/izaa085
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Expression of SARS-CoV-2 Entry Molecules ACE2 and TMPRSS2 in the Gut of Patients With IBD. [Abstract]: BACKGROUND: Patients with inflammatory bowel disease (IBD) have intestinal inflammation and are treated with immune-modulating medications. In the face of the coronavirus disease-19 pandemic, we do not know w...
32,421,381
Circulation
Deep Vein Thrombosis in Hospitalized Patients With COVID-19 in Wuhan, China: Prevalence, Risk Factors, and Outcome.
BACKGROUND: To investigate deep vein thrombosis (DVT) in hospitalized patients with coronavirus disease 2019 (COVID-19), we performed a single institutional study to evaluate its prevalence, risk factors, prognosis, and potential thromboprophylaxis strategies in a large referral and treatment center. METHODS: We studie...
covid-19;coronavirus;venous thrombosis
Journal Article;Research Support, Non-U.S. Gov't
Zhang, Li;Feng, Xiaokai;Zhang, Danqing;Jiang, Chunguo;Mei, Heng;Wang, Jing;Zhang, Cuihong;Li, Hong;Xia, Xiaoling;Kong, Shuangshuang;Liao, Jia;Jia, Huijun;Pang, Xueqin;Song, Yue;Tian, Ying;Wang, Bin;Wu, Chun;Yuan, Hongliang;Zhang, Yongxing;Li, Yuman;Sun, Wei;Zhang, Yanting;Zhu, Shuangshuang;Wang, Shuyuan;Xie, Yuji;Ge, S...
10.1161/CIRCULATIONAHA.120.046702
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Deep Vein Thrombosis in Hospitalized Patients With COVID-19 in Wuhan, China: Prevalence, Risk Factors, and Outcome. [Abstract]: BACKGROUND: To investigate deep vein thrombosis (DVT) in hospitalized patients with coronavirus disease 2019 (COVID-19), we performed a single institutional study to evaluate its prev...
32,877,380
Ann Ital Chir
An infection-oriented approach for thoracic endovascular aortic repair in a SARS-CoV-2 positive patient. A case report.
CASE REPORT: A 64-year-old woman presented to our emergency department during the outbreak of the covid-19 emergency in Italy with syncope, anosmia, mild dyspnoea and atypical chest and dorsal pain. A chest CT scan showed an acute type B aortic dissection (ATBAD) and bilateral lung involvement with ground-glass opacity...
Case Reports;Journal Article
Rossi, Giovanni;Ferrari, Stefano Aldo;Sommaruga, Simona;Muzzarelli, Lorenzo;Piconi, Stefania
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: An infection-oriented approach for thoracic endovascular aortic repair in a SARS-CoV-2 positive patient. A case report. [Abstract]: CASE REPORT: A 64-year-old woman presented to our emergency department during the outbreak of the covid-19 emergency in Italy with syncope, anosmia, mild dyspnoea and atypical che...
32,810,517
J Allergy Clin Immunol
Allergic disorders and susceptibility to and severity of COVID-19: A nationwide cohort study.
BACKGROUND: There is inconclusive and controversial evidence of the association between allergic diseases and the risk of adverse clinical outcomes of coronavirus disease 2019 (COVID-19). OBJECTIVE: We sought to determine the association of allergic disorders with the likelihood of a positive severe acute respiratory s...
covid-19;allergic rhinitis;asthma;atopic dermatitis
Journal Article;Research Support, Non-U.S. Gov't
Yang, Jee Myung;Koh, Hyun Yong;Moon, Sung Yong;Yoo, In Kyung;Ha, Eun Kyo;You, Seulgi;Kim, So Young;Yon, Dong Keon;Lee, Seung Won
10.1016/j.jaci.2020.08.008
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Allergic disorders and susceptibility to and severity of COVID-19: A nationwide cohort study. [Abstract]: BACKGROUND: There is inconclusive and controversial evidence of the association between allergic diseases and the risk of adverse clinical outcomes of coronavirus disease 2019 (COVID-19). OBJECTIVE: We sou...
32,611,912
Indian J Med Res
COVID-19 pandemic from an ophthalmology point of view.
Coronavirus disease 2019 (COVID-19) is caused by a highly contagious RNA virus termed as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Ophthalmologists are at high-risk due to their proximity and short working distance at the time of slit-lamp examination. Eye care professionals can be caught unaware be...
chloroquine - contact lens - coronavirus - eye donation - eye shields - hydroxychloroquine - ophthalmologist
Journal Article;Review
Gupta, Parul Chawla;Kumar, M Praveen;Ram, Jagat
10.4103/ijmr.IJMR_1369_20
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 pandemic from an ophthalmology point of view. [Abstract]: Coronavirus disease 2019 (COVID-19) is caused by a highly contagious RNA virus termed as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Ophthalmologists are at high-risk due to their proximity and short working distance at the ti...
32,809,210
Adv Ther
Perspectives on the Early Quality of Evidence Guiding the Therapeutic Management of SARS-CoV-2: A Systematic Literature Review.
BACKGROUND: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak is a serious health concern. Repurposing of existing drugs indicated for other conditions seems to be the first choice for immediate therapeutic management. The quality of early evidence favoring the different treatment options needs ...
clinical cure;evidence;infectious disease;sars-cov-2;treatment options;virological cure
Journal Article;Systematic Review
Subramanian, Kaushik;Nalli, Anuradha;Senthil, Vinitha;Jain, Saurabh;Nayak, Aravind;Bhat, Amit
10.1007/s12325-020-01460-5
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Perspectives on the Early Quality of Evidence Guiding the Therapeutic Management of SARS-CoV-2: A Systematic Literature Review. [Abstract]: BACKGROUND: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak is a serious health concern. Repurposing of existing drugs indicated for other condit...
32,589,600
Diagnosis (Berl)
Biochemical biomarkers alterations in Coronavirus Disease 2019 (COVID-19).
Coronavirus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a respiratory disease, which can evolve into multi-organ failure (MOF), leading to death. Several biochemical alterations have been described in COVID-19 patients. To date, many biomarkers reflecting the main p...
covid-19;sars-cov-2;biochemical alterations;biomarkers;laboratory
Journal Article;Review
Ciaccio, Marcello;Agnello, Luisa
10.1515/dx-2020-0057
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Biochemical biomarkers alterations in Coronavirus Disease 2019 (COVID-19). [Abstract]: Coronavirus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a respiratory disease, which can evolve into multi-organ failure (MOF), leading to death. Several biochemical alte...
32,904,638
ERJ Open Res
German bronchoscopy unit readiness for the COVID-19 pandemic: a nationwide survey.
Background: The worldwide impact of the coronavirus disease 2019 (COVID-19) pandemic is unprecedented. Among the aerosol generating procedures, bronchoscopy in particular is an indispensable diagnostic and therapeutic tool that comes with a high risk of infection. Therefore, national societies have issued guidance stat...
Journal Article
Heidemann, Clara S;Garbe, Jakob;Damm, Marko;Walter, Steffen;Michl, Patrick;Rosendahl, Jonas;Darwiche, Kaid;Eisenmann, Stephan
10.1183/23120541.00396-2020
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: German bronchoscopy unit readiness for the COVID-19 pandemic: a nationwide survey. [Abstract]: Background: The worldwide impact of the coronavirus disease 2019 (COVID-19) pandemic is unprecedented. Among the aerosol generating procedures, bronchoscopy in particular is an indispensable diagnostic and therapeuti...
32,535,550
J Epidemiol Community Health
The COVID-19 pandemic and health inequalities.
This essay examines the implications of the COVID-19 pandemic for health inequalities. It outlines historical and contemporary evidence of inequalities in pandemics-drawing on international research into the Spanish influenza pandemic of 1918, the H1N1 outbreak of 2009 and the emerging international estimates of socio-...
deprivation;employment;gender;geography;health inequalities
Journal Article;Research Support, Non-U.S. Gov't
Bambra, Clare;Riordan, Ryan;Ford, John;Matthews, Fiona
10.1136/jech-2020-214401
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The COVID-19 pandemic and health inequalities. [Abstract]: This essay examines the implications of the COVID-19 pandemic for health inequalities. It outlines historical and contemporary evidence of inequalities in pandemics-drawing on international research into the Spanish influenza pandemic of 1918, the H1N1...
32,498,139
J Prev Med Public Health
Characteristics of the COVID-19 Outbreak in Korea From the Mass Infection Perspective.
On December 31, 2019, the Chinese government officially announced that the country had some cases of pneumonia with an unknown cause. By February 8, 2020, there were 24 confirmed cases in Korea, and the number of cases has steadily increased since then. On March 9, 2020, the cumulative number of confirmed cases in Kore...
covid-19;group meetings;massive infection;perspectives;prevent;religious services
Journal Article
Kang, Yun Jung
10.3961/jpmph.20.072
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Characteristics of the COVID-19 Outbreak in Korea From the Mass Infection Perspective. [Abstract]: On December 31, 2019, the Chinese government officially announced that the country had some cases of pneumonia with an unknown cause. By February 8, 2020, there were 24 confirmed cases in Korea, and the number of...
32,900,176
Tidsskr Nor Laegeforen
Pasient med alvorlig covid-19 behandlet med rekonvalesensplasma.
BACKGROUND: COVID-19 can lead to life-threatening disease. While awaiting vaccines or documented specific therapeutic agents, several alternative treatment options are under investigation. This is a case report of the first COVID-19 patient treated with convalescent plasma in Norway. CASE PRESENTATION: A patient with s...
Case Reports;Journal Article
Hahn, Michael;Condori, Maria Elena Huanca;Totland, Atle;Kristoffersen, Einar K;Hervig, Tor Audun
10.4045/tidsskr.20.0501
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Pasient med alvorlig covid-19 behandlet med rekonvalesensplasma. [Abstract]: BACKGROUND: COVID-19 can lead to life-threatening disease. While awaiting vaccines or documented specific therapeutic agents, several alternative treatment options are under investigation. This is a case report of the first COVID-19 p...
32,943,474
Postgrad Med J
COVID-19 and the heart: what we have learnt so far.
Since the outbreak of COVID-19 or coronavirus disease caused by severe acute respiratory syndrome coronavirus 2 from Wuhan, China, the cardiology fraternity's interest has been drawn towards the pandemic with a high case fatality rate of 10.5% and 6% in patients with heart disease and hypertension, respectively. One of...
angiotensin receptor blocker;arrhythmias;covid-19;carditis;sars-cov-2
Journal Article;Review
Shaha, Kunal Bikram;Manandhar, Dhiraj Narayan;Cho, Jung Rae;Adhikari, Ashok;K C, Man Bahadur
10.1136/postgradmedj-2020-138284
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: COVID-19 and the heart: what we have learnt so far. [Abstract]: Since the outbreak of COVID-19 or coronavirus disease caused by severe acute respiratory syndrome coronavirus 2 from Wuhan, China, the cardiology fraternity's interest has been drawn towards the pandemic with a high case fatality rate of 10.5% and...
32,910,106
Simul Healthc
In Situ Simulation: An Essential Tool for Safe Preparedness for the COVID-19 Pandemic.
INTRODUCTION: Working under extreme stress can cause medical professionals to deviate from clinical guidelines even if they know of their existence, let alone in situations such as COVID-19 where guidelines are unclear, fluid, and resources limited. In situ simulation has been proven an effective tool for training medi...
Journal Article
Sharara-Chami, Rana;Sabouneh, Rami;Zeineddine, Rida;Banat, Rim;Fayad, Joe;Lakissian, Zavi
10.1097/SIH.0000000000000504
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: In Situ Simulation: An Essential Tool for Safe Preparedness for the COVID-19 Pandemic. [Abstract]: INTRODUCTION: Working under extreme stress can cause medical professionals to deviate from clinical guidelines even if they know of their existence, let alone in situations such as COVID-19 where guidelines are u...
32,818,545
Life Sci
Utilizing drug repurposing against COVID-19 - Efficacy, limitations, and challenges.
The recent outbreak of Coronavirus disease (COVID-19), first in Eastern Asia and then essentially across the world has been declared a pandemic by the WHO. COVID-19 is caused by a novel virus SARS-CoV2 (2019-nCoV), against which there is currently no vaccine available; and current antiviral therapies have failed, causi...
covid-19;drug repurposing;fda approved drugs;localized delivery;sars-cov2
Journal Article;Review
Parvathaneni, Vineela;Gupta, Vivek
10.1016/j.lfs.2020.118275
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Utilizing drug repurposing against COVID-19 - Efficacy, limitations, and challenges. [Abstract]: The recent outbreak of Coronavirus disease (COVID-19), first in Eastern Asia and then essentially across the world has been declared a pandemic by the WHO. COVID-19 is caused by a novel virus SARS-CoV2 (2019-nCoV),...
32,719,804
Front Med (Lausanne)
Clinical Characteristics of Adult Fevered COVID-19 Patients and Predictors for Developing Severe Events.
Aim: Clinical findings indicated that a fraction of coronavirus disease 2019 (COVID-19) patients did not show fever. However, the difference between the clinical characteristics of fevered and non-fevered patients is still unclear. The aim of the present study was to describe the clinical characteristics of these patie...
c-reactive protein;covid-19;adult;fever;lymphocytes
Journal Article
Wang, Guyi;Zhang, Quan;Wu, Chenfang;Wu, Fang;Yu, Bo;Lv, Jianlei;Zhang, Siye;Wu, Guobao;Zhong, Yanjun
10.3389/fmed.2020.00324
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical Characteristics of Adult Fevered COVID-19 Patients and Predictors for Developing Severe Events. [Abstract]: Aim: Clinical findings indicated that a fraction of coronavirus disease 2019 (COVID-19) patients did not show fever. However, the difference between the clinical characteristics of fevered and n...
32,750,010
J Med Internet Res
Managing COVID-19 With a Clinical Decision Support Tool in a Community Health Network: Algorithm Development and Validation.
BACKGROUND: The coronavirus disease (COVID-19) pandemic has resulted in significant morbidity and mortality; large numbers of patients require intensive care, which is placing strain on health care systems worldwide. There is an urgent need for a COVID-19 disease severity assessment that can assist in patient triage an...
covid-19;app;artificial intelligence;biomarkers;clinical decision support system;coronavirus;disease severity;family health center;mobile app;point of care
Journal Article
McRae, Michael P;Dapkins, Isaac P;Sharif, Iman;Anderman, Judd;Fenyo, David;Sinokrot, Odai;Kang, Stella K;Christodoulides, Nicolaos J;Vurmaz, Deniz;Simmons, Glennon W;Alcorn, Timothy M;Daoura, Marco J;Gisburne, Stu;Zar, David;McDevitt, John T
10.2196/22033
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Managing COVID-19 With a Clinical Decision Support Tool in a Community Health Network: Algorithm Development and Validation. [Abstract]: BACKGROUND: The coronavirus disease (COVID-19) pandemic has resulted in significant morbidity and mortality; large numbers of patients require intensive care, which is placin...
32,335,456
Med Hypotheses
The old but new: Can unfractioned heparin and low molecular weight heparins inhibit proteolytic activation and cellular internalization of SARS-CoV2 by inhibition of host cell proteases?
Currently, our world is facing the 2019 Novel Coronavirus (COVID-19) outbreak and tremendous efforts are made for developing drugs to treat and vaccines to prevent the disease. At present, there is no specific antiviral drug or vaccine for COVID-19. The pathogenic infectivity of the virus requires the S1 subunit of the...
covid-19;factor xa;heparin;host proteases;low molecular weight heparin;sars-cov2
Journal Article
Belen-Apak, F B;Sarialioglu, F
10.1016/j.mehy.2020.109743
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: The old but new: Can unfractioned heparin and low molecular weight heparins inhibit proteolytic activation and cellular internalization of SARS-CoV2 by inhibition of host cell proteases? [Abstract]: Currently, our world is facing the 2019 Novel Coronavirus (COVID-19) outbreak and tremendous efforts are made fo...
32,686,094
Int Nurs Rev
Nurses' health beliefs about paper face masks in Japan, Australia and China: a qualitative descriptive study.
AIM: To explore the health beliefs of clinical and academic nurses from Japan, Australia and China regarding wearing paper masks to protect themselves and others, and to identify differences in participants' health beliefs regarding masks. BACKGROUND: The correct use of face masks and consensus among health professiona...
covid-19;culture;face masks;health beliefs;health policy;infection control;nurses;respiratory disease
Journal Article
Omura, M;Stone, T E;Petrini, M A;Cao, R
10.1111/inr.12607
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Nurses' health beliefs about paper face masks in Japan, Australia and China: a qualitative descriptive study. [Abstract]: AIM: To explore the health beliefs of clinical and academic nurses from Japan, Australia and China regarding wearing paper masks to protect themselves and others, and to identify difference...
32,524,227
Arch Orthop Trauma Surg
Assessing the spreading potential of an undetected case of COVID-19 in orthopaedic surgery.
BACKGROUND: With the novel coronavirus-induced disease (COVID-19), there is the fear of nosocomial infections and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmissions to healthcare workers (HCW). We report the case of a 64-year-old male patient who underwent explantation of a shoulder prosthesis d...
covid-19;infection;mdro;nosocomial;orthopaedics;sars-cov-2
Journal Article
Schneider, K N;Correa-Martinez, C L;Gosheger, G;Rickert, C;Schorn, D;Mellmann, A;Schwierzeck, V;Kampmeier, S
10.1007/s00402-020-03516-1
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Assessing the spreading potential of an undetected case of COVID-19 in orthopaedic surgery. [Abstract]: BACKGROUND: With the novel coronavirus-induced disease (COVID-19), there is the fear of nosocomial infections and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmissions to healthcare work...
32,627,515
Pol Arch Intern Med
Dysregulation of the immune system as a driver of the critical course of novel coronavirus disease 2019.
Novel coronavirus disease 2019 (COVID19) is a highly contagious, respiratory disease caused by the newly emerged severe acute respiratory syndrome coronavirus 2 (SARSCoV2). Given that inflammatory immune cells may induce severe lung injury, the involvement of immunological factors in the pathogenesis of the disease can...
Journal Article;Review
Kosmaczewska, Agata;Frydecka, Irena
10.20452/pamw.15482
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Dysregulation of the immune system as a driver of the critical course of novel coronavirus disease 2019. [Abstract]: Novel coronavirus disease 2019 (COVID19) is a highly contagious, respiratory disease caused by the newly emerged severe acute respiratory syndrome coronavirus 2 (SARSCoV2). Given that inflammato...
32,632,645
J Community Health
Knowledge, Attitude, and Practices Toward COVID-19 in Primary Healthcare Providers: A Cross-Sectional Study from Three Tertiary Care Hospitals of Peshawar, Pakistan.
An online cross-sectional study was carried out to evaluate the knowledge, attitude, and practice about coronavirus disease 2019 (COVID-19) among primary health care providers (PHPs) at three tertiary care hospital, Peshawar, Pakistan. Data was collected via email and online social media platforms. Statistical package ...
attitude;covid-19;knowledge;peshawar;practices;primary healthcare providers
Journal Article
Hussain, Iltaf;Majeed, Abdul;Imran, Imran;Ullah, Muhib;Hashmi, Furqan K;Saeed, Hamid;Chaudhry, Muhammad O;Rasool, Muhammad F
10.1007/s10900-020-00879-9
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Knowledge, Attitude, and Practices Toward COVID-19 in Primary Healthcare Providers: A Cross-Sectional Study from Three Tertiary Care Hospitals of Peshawar, Pakistan. [Abstract]: An online cross-sectional study was carried out to evaluate the knowledge, attitude, and practice about coronavirus disease 2019 (COV...
32,326,426
J Clin Med
COVID-19: A Recommendation to Examine the Effect of Mouthrinses with beta-Cyclodextrin Combined with Citrox in Preventing Infection and Progression.
Considered to be a major portal of entry for infectious agents, the oral cavity is directly associated with the evolutionary process of SARS-CoV-2 in its inhalation of ambient particles in the air and in expectorations. Some new generations of mouth rinses currently on the market have ingredients that could contribute ...
2019-ncov;covid-19;citrox;sars-cov-2;microbiome;mouthrinse;oral cavity;viral load;beta-cyclodextrins
Editorial
Carrouel, Florence;Conte, Maria Pia;Fisher, Julian;Goncalves, Lucio Souza;Dussart, Claude;Llodra, Juan Carlos;Bourgeois, Denis
10.3390/jcm9041126
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: COVID-19: A Recommendation to Examine the Effect of Mouthrinses with beta-Cyclodextrin Combined with Citrox in Preventing Infection and Progression. [Abstract]: Considered to be a major portal of entry for infectious agents, the oral cavity is directly associated with the evolutionary process of SARS-CoV-2 in ...
32,766,266
Front Med (Lausanne)
Administration of Immunoglobulins in SARS-CoV-2-Positive Patient Is Associated With Fast Clinical and Radiological Healing: Case Report.
Polyclonal preparation of IgM as an adjuvant therapy has been reported as a relevant immunomodulant therapy in several infectious diseases, exhibiting, in most cases, improvement of the clinical course. No drug has demonstrated therapeutic efficacy for COVID-19. Immunomodulatory treatment with hydroxychloroquine and bi...
covid 19;pentaglobin;sars-cov2;case report;immunoglobulin;pneumonia
Case Reports
Carannante, Novella;Fiorentino, Giuseppe;Corcione, Antonio;Di Sarno, Raffaele;Spatarella, Micaela;Maturo, Nicola;Fragranza, Fiorentino;Di Micco, Pierpaolo
10.3389/fmed.2020.00388
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Administration of Immunoglobulins in SARS-CoV-2-Positive Patient Is Associated With Fast Clinical and Radiological Healing: Case Report. [Abstract]: Polyclonal preparation of IgM as an adjuvant therapy has been reported as a relevant immunomodulant therapy in several infectious diseases, exhibiting, in most ca...
32,561,389
J Allergy Clin Immunol
Risk and management of patients with mastocytosis and MCAS in the SARS-CoV-2 (COVID-19) pandemic: Expert opinions.
The coronavirus disease 2019 (COVID-19) (caused by severe acute respiratory syndrome coronavirus 2) pandemic has massively distorted our health care systems and caused catastrophic consequences in our affected communities. The number of victims continues to increase, and patients at risk can only be protected to a degr...
covid-19;kit d816v;mast cells;sars-cov-2;coronavirus;mast cell activation syndrome;mastocytosis;tryptase
Journal Article
Valent, Peter;Akin, Cem;Bonadonna, Patrizia;Brockow, Knut;Niedoszytko, Marek;Nedoszytko, Boguslaw;Butterfield, Joseph H;Alvarez-Twose, Ivan;Sotlar, Karl;Schwaab, Juliana;Jawhar, Mohamad;Reiter, Andreas;Castells, Mariana;Sperr, Wolfgang R;Kluin-Nelemans, Hanneke C;Hermine, Olivier;Gotlib, Jason;Zanotti, Roberta;Broesby-...
10.1016/j.jaci.2020.06.009
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Risk and management of patients with mastocytosis and MCAS in the SARS-CoV-2 (COVID-19) pandemic: Expert opinions. [Abstract]: The coronavirus disease 2019 (COVID-19) (caused by severe acute respiratory syndrome coronavirus 2) pandemic has massively distorted our health care systems and caused catastrophic con...
32,429,786
J Matern Fetal Neonatal Med
COVID-19 pneumonia and pregnancy; a systematic review and meta-analysis.
Background: The new SARS-CoV-2 originated from Wuhan, China is spreading rapidly worldwide. A number of SARS-CoV-2 positive pregnant women have been reported. However, more information is still needed on the pregnancy outcome and the neonates regarding COVID-19 pneumonia.Material and Methods: A systematic search was do...
covid-19 pneumonia;sars-cov-2 positive pregnant women;maternal-fetal outcomes;meta-analysis;systematic review
Journal Article
Kasraeian, Maryam;Zare, Marjan;Vafaei, Homeira;Asadi, Nasrin;Faraji, Azam;Bazrafshan, Khadijeh;Roozmeh, Shohreh
10.1080/14767058.2020.1763952
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: COVID-19 pneumonia and pregnancy; a systematic review and meta-analysis. [Abstract]: Background: The new SARS-CoV-2 originated from Wuhan, China is spreading rapidly worldwide. A number of SARS-CoV-2 positive pregnant women have been reported. However, more information is still needed on the pregnancy outcome ...
32,677,545
J Biomol Struct Dyn
Approach to the mechanism of action of hydroxychloroquine on SARS-CoV-2: a molecular docking study.
We aimed to analyze the interactions of both hydroxychloroquine and chloroquine with SARS-CoV-2 and identify their possible role for the prevention/treatment of COVID-19 by molecular docking studies. Protein crystal structures of SARS-CoV-2 and ACE2, the compounds hydroxychloroquine and chloroquine, and other ligand st...
ace2;hydroxychloroquine;sars-cov-2;chloroquine;molecular docking
Journal Article
Celi K, Ismail;Onay-Besi Kci, Arzu;Ayhan-Kilcigi L, Gulgun
10.1080/07391102.2020.1792993
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Approach to the mechanism of action of hydroxychloroquine on SARS-CoV-2: a molecular docking study. [Abstract]: We aimed to analyze the interactions of both hydroxychloroquine and chloroquine with SARS-CoV-2 and identify their possible role for the prevention/treatment of COVID-19 by molecular docking studies....
32,222,993
J Med Virol
Genomic characterization and phylogenetic analysis of SARS-COV-2 in Italy.
This report describes the isolation, molecular characterization, and phylogenetic analysis of the first three complete genomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) isolated from three patients involved in the first outbreak of COVID-19 in Lombardy, Italy. Early molecular epidemiological traci...
covid-19;complete genomes of sars-cov-2;phylogenetic analysis
Journal Article
Zehender, Gianguglielmo;Lai, Alessia;Bergna, Annalisa;Meroni, Luca;Riva, Agostino;Balotta, Claudia;Tarkowski, Maciej;Gabrieli, Arianna;Bernacchia, Dario;Rusconi, Stefano;Rizzardini, Giuliano;Antinori, Spinello;Galli, Massimo
10.1002/jmv.25794
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Genomic characterization and phylogenetic analysis of SARS-COV-2 in Italy. [Abstract]: This report describes the isolation, molecular characterization, and phylogenetic analysis of the first three complete genomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) isolated from three patients invo...
32,296,544
Virus Evol
An emergent clade of SARS-CoV-2 linked to returned travellers from Iran.
The SARS-CoV-2 epidemic has rapidly spread outside China with major outbreaks occurring in Italy, South Korea, and Iran. Phylogenetic analyses of whole-genome sequencing data identified a distinct SARS-CoV-2 clade linked to travellers returning from Iran to Australia and New Zealand. This study highlights potential vir...
covid-19;sars-cov-2;genome sequencing;phylogenetics
Journal Article
Eden, John-Sebastian;Rockett, Rebecca;Carter, Ian;Rahman, Hossinur;de Ligt, Joep;Hadfield, James;Storey, Matthew;Ren, Xiaoyun;Tulloch, Rachel;Basile, Kerri;Wells, Jessica;Byun, Roy;Gilroy, Nicky;O'Sullivan, Matthew V;Sintchenko, Vitali;Chen, Sharon C;Maddocks, Susan;Sorrell, Tania C;Holmes, Edward C;Dwyer, Dominic E;Ko...
10.1093/ve/veaa027
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: An emergent clade of SARS-CoV-2 linked to returned travellers from Iran. [Abstract]: The SARS-CoV-2 epidemic has rapidly spread outside China with major outbreaks occurring in Italy, South Korea, and Iran. Phylogenetic analyses of whole-genome sequencing data identified a distinct SARS-CoV-2 clade linked to tr...
32,486,563
Zhonghua Kou Qiang Yi Xue Za Zhi
[Development and improvement of Chinese oral public health system].
The pandemic of COVID-19 in early 2020 is a big challenge to the mechanism of major epidemic prevention and control, the national public health management system, as well as medical and health resources in China. Going through the COVID-19 crisis, we should fully understand the problems and vulnerabilities of the curre...
oral disease;oral public health system;public health administration
Journal Article
Zeng, X J;Zhou, X D;Chen, W X
10.3760/cma.j.cn112144-20200311-00143
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [Development and improvement of Chinese oral public health system]. [Abstract]: The pandemic of COVID-19 in early 2020 is a big challenge to the mechanism of major epidemic prevention and control, the national public health management system, as well as medical and health resources in China. Going through the ...
32,671,732
Eur Geriatr Med
Clinical presentation and outcome across age categories among patients with COVID-19 admitted to a Spanish Emergency Department.
PURPOSE: To determine the differences by age-dependent categories in the clinical profile, presentation, management, and short-term outcomes of patients with laboratory-confirmed COVID-19 admitted to a Spanish Emergency Department (ED). METHODS: Secondary analysis of COVID-19_URG-HCSC registry. We included all consecut...
age;covid-19;emergency department;older
Journal Article
Martin-Sanchez, F Javier;Del Toro, Enrique;Cardassay, Eduardo;Valls Carbo, Adrian;Cuesta, Federico;Vigara, Marta;Gil, Pedro;Lopez Picado, Amanda Lopez;Martinez Valero, Carmen;Miranda, Juande D;Lopez-Ayala, Pedro;Chaparro, David;Cozar Lopez, Gabriel;Del Mar Suarez-Cadenas, Maria;Jerez Fernandez, Pablo;Angos, Beatriz;Dia...
10.1007/s41999-020-00359-2
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical presentation and outcome across age categories among patients with COVID-19 admitted to a Spanish Emergency Department. [Abstract]: PURPOSE: To determine the differences by age-dependent categories in the clinical profile, presentation, management, and short-term outcomes of patients with laboratory-c...
32,536,763
Chaos Solitons Fractals
Investigating the dynamics of COVID-19 pandemic in India under lockdown.
In this paper, we investigate the ongoing dynamics of COVID-19 in India after its emergence in Wuhan, China in December 2019. We discuss the effect of nationwide lockdown implemented in India on March 25, 2020 to prevent the spread of COVID-19. Susceptible-Exposed-Infectious-Recovered (SEIR) model is used to forecast a...
Journal Article
Pai, Chintamani;Bhaskar, Ankush;Rawoot, Vaibhav
10.1016/j.chaos.2020.109988
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Investigating the dynamics of COVID-19 pandemic in India under lockdown. [Abstract]: In this paper, we investigate the ongoing dynamics of COVID-19 in India after its emergence in Wuhan, China in December 2019. We discuss the effect of nationwide lockdown implemented in India on March 25, 2020 to prevent the s...
32,092,296
J Am Coll Radiol
Coronavirus (COVID-19) Outbreak: What the Department of Radiology Should Know.
In December 2019, a novel coronavirus (COVID-19) pneumonia emerged in Wuhan, China. Since then, this highly contagious COVID-19 has been spreading worldwide, with a rapid rise in the number of deaths. Novel COVID-19-infected pneumonia (NCIP) is characterized by fever, fatigue, dry cough, and dyspnea. A variety of chest...
covid-19;coronavirus;infection control;pneumonia;safety
Journal Article;Review
Kooraki, Soheil;Hosseiny, Melina;Myers, Lee;Gholamrezanezhad, Ali
10.1016/j.jacr.2020.02.008
[ 0, 0, 1, 1, 0, 0, 0 ]
[Title]: Coronavirus (COVID-19) Outbreak: What the Department of Radiology Should Know. [Abstract]: In December 2019, a novel coronavirus (COVID-19) pneumonia emerged in Wuhan, China. Since then, this highly contagious COVID-19 has been spreading worldwide, with a rapid rise in the number of deaths. Novel COVID-19-infe...
32,651,031
J Diabetes Complications
COVID-19 in people living with diabetes: An international consensus.
The COVID-19 pandemic has added an enormous toll to the existing challenge of diabetes care world-wide. A large proportion of patients with COVID-19 requiring hospitalization and/or succumbing to the disease have had diabetes and other chronic conditions as underlying risk factors. In particular, individuals belonging ...
covid-19;covid-19 and diabetes;consensus;diabetes;diabetes complications;diabetes management
Journal Article;Review
Caballero, A E;Ceriello, A;Misra, A;Aschner, P;McDonnell, M E;Hassanein, M;Ji, L;Mbanya, J C;Fonseca, V A
10.1016/j.jdiacomp.2020.107671
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 in people living with diabetes: An international consensus. [Abstract]: The COVID-19 pandemic has added an enormous toll to the existing challenge of diabetes care world-wide. A large proportion of patients with COVID-19 requiring hospitalization and/or succumbing to the disease have had diabetes and ...
32,454,891
Cogn Behav Therap
Adapting IAPT services to support frontline NHS staff during the Covid-19 pandemic: the Homerton Covid Psychological Support (HCPS) pathway.
The Coronavirus (Covid-19) pandemic is exerting unprecedented pressure on NHS Health and Social Care provisions, with frontline staff, such as those of critical care units, encountering vast practical and emotional challenges on a daily basis. Although staff are being supported through organisational provisions, facili...
iapt;cognitive behavioural therapy;disaster response;healthcare workers;pandemic;trauma
Journal Article
Cole, C L;Waterman, S;Stott, J;Saunders, R;Buckman, J E J;Pilling, S;Wheatley, J
10.1017/S1754470X20000148
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Adapting IAPT services to support frontline NHS staff during the Covid-19 pandemic: the Homerton Covid Psychological Support (HCPS) pathway. [Abstract]: The Coronavirus (Covid-19) pandemic is exerting unprecedented pressure on NHS Health and Social Care provisions, with frontline staff, such as those of critic...
32,909,973
J Clin Gastroenterol
Personal Protective Equipment for Endoscopy in Low-Resource Settings During the COVID-19 Pandemic: Guidance From the World Gastroenterology Organisation.
Performance of endoscopic procedures is associated with a risk of infection from COVID-19. This risk can be reduced by the use of personal protective equipment (PPE). However, shortage of PPE has emerged as an important issue in managing the pandemic in both traditionally high and low-resource areas. A group of clinici...
Comparative Study;Journal Article;Review
Leddin, Desmond;Armstrong, David;Raja Ali, Raja A;Barkun, Alan;Butt, Amna S;Chen, Ye;Khara, Harshit S;Lee, Yeong Yeh;Leung, Wai Keung;Macrae, Finlay;Makharia, Govind;Malekzadeh, Reza;Makhoul, Elias;Sadeghi, Anahita;Saurin, Jean-Christophe;Topazian, Mark;Thomson, Sandie R;Veitch, Andrew;Wu, Kaichun
10.1097/MCG.0000000000001411
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Personal Protective Equipment for Endoscopy in Low-Resource Settings During the COVID-19 Pandemic: Guidance From the World Gastroenterology Organisation. [Abstract]: Performance of endoscopic procedures is associated with a risk of infection from COVID-19. This risk can be reduced by the use of personal protec...
32,779,891
FEBS J
Sympathetic activation: a potential link between comorbidities and COVID-19.
In coronavirus disease 2019 (COVID-19), higher morbidity and mortality are associated with age, male gender, and comorbidities, such as chronic lung diseases, cardiovascular pathologies, hypertension, kidney diseases, diabetes mellitus, and obesity. All of the above conditions are characterized by increased sympathetic...
covid-19;sars-cov-2;autonomic nervous system;diabetes;heart failure;hypertension;kidney disease;obesity;smoking;sympathoactivation
Journal Article;Review
Porzionato, Andrea;Emmi, Aron;Barbon, Silvia;Boscolo-Berto, Rafael;Stecco, Carla;Stocco, Elena;Macchi, Veronica;De Caro, Raffaele
10.1111/febs.15481
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Sympathetic activation: a potential link between comorbidities and COVID-19. [Abstract]: In coronavirus disease 2019 (COVID-19), higher morbidity and mortality are associated with age, male gender, and comorbidities, such as chronic lung diseases, cardiovascular pathologies, hypertension, kidney diseases, diab...
32,510,329
Elife
A Global lmmunological Observatory to meet a time of pandemics.
SARS-CoV-2 presents an unprecedented international challenge, but it will not be the last such threat. Here, we argue that the world needs to be much better prepared to rapidly detect, define and defeat future pandemics. We propose that a Global Immunological Observatory and associated developments in systems immunolog...
covid-19;sars-cov-2;epidemiology;global health;global surveillance;human;immunology;inflammation;pandemic;science forum;serology
Journal Article
Mina, Michael J;Metcalf, C Jessica E;McDermott, Adrian B;Douek, Daniel C;Farrar, Jeremy;Grenfell, Bryan T
10.7554/eLife.58989
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: A Global lmmunological Observatory to meet a time of pandemics. [Abstract]: SARS-CoV-2 presents an unprecedented international challenge, but it will not be the last such threat. Here, we argue that the world needs to be much better prepared to rapidly detect, define and defeat future pandemics. We propose tha...
32,604,223
Shock
Therapeutic Potential of B-1a Cells in COVID-19.
Coronavirus disease 2019 (COVID-19) is a life-threatening respiratory illness caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Its clinical presentation can vary from the asymptomatic state to acute respiratory distress syndrome (ARDS) and multi-organ dysfunction. Due to our insufficien...
Journal Article;Review
Aziz, Monowar;Brenner, Max;Wang, Ping
10.1097/SHK.0000000000001610
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Therapeutic Potential of B-1a Cells in COVID-19. [Abstract]: Coronavirus disease 2019 (COVID-19) is a life-threatening respiratory illness caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Its clinical presentation can vary from the asymptomatic state to acute respiratory distre...
32,293,753
J Med Virol
The impact of COPD and smoking history on the severity of COVID-19: A systemic review and meta-analysis.
Comorbidities are associated with the severity of coronavirus disease 2019 (COVID-19). This meta-analysis aimed to explore the risk of severe COVID-19 in patients with pre-existing chronic obstructive pulmonary disease (COPD) and ongoing smoking history. A comprehensive systematic literature search was carried out to f...
copd;covid-2019;smoking
Journal Article;Meta-Analysis;Research Support, Non-U.S. Gov't;Systematic Review
Zhao, Qianwen;Meng, Meng;Kumar, Rahul;Wu, Yinlian;Huang, Jiaofeng;Lian, Ningfang;Deng, Yunlei;Lin, Su
10.1002/jmv.25889
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: The impact of COPD and smoking history on the severity of COVID-19: A systemic review and meta-analysis. [Abstract]: Comorbidities are associated with the severity of coronavirus disease 2019 (COVID-19). This meta-analysis aimed to explore the risk of severe COVID-19 in patients with pre-existing chronic obstr...
32,512,532
Asian J Psychiatr
Lived experiences of the corona survivors (patients admitted in COVID wards): A narrative real-life documented summaries of internalized guilt, shame, stigma, anger.
COVID-19 pandemic has emerged as a disaster for the human beings. All the Governments across the globe have been preparing to deal with this medical emergency, which is known to be associated with mortality in about 5% of the sufferers. Gradually, it is seen that, many patients with COVID-19 infection have mild symptom...
covid survivors;covid-19;emotional experiences
Journal Article
Sahoo, Swapnajeet;Mehra, Aseem;Suri, Vikas;Malhotra, Pankaj;Yaddanapudi, Lakshmi Narayana;Dutt Puri, Goverdhan;Grover, Sandeep
10.1016/j.ajp.2020.102187
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Lived experiences of the corona survivors (patients admitted in COVID wards): A narrative real-life documented summaries of internalized guilt, shame, stigma, anger. [Abstract]: COVID-19 pandemic has emerged as a disaster for the human beings. All the Governments across the globe have been preparing to deal wi...
32,558,308
Mol Genet Genomic Med
Genetic variability of human angiotensin-converting enzyme 2 (hACE2) among various ethnic populations.
BACKGROUND: There appears to be large regional variation for susceptibility, severity, and mortality for COVID-19 infections. Numerous potential factors could explain the wide variability in the number of infections and death among the countries. We examined genetic differences in the human angiotensin-converting enzym...
covid-19;sars-cov-2;angiotensin-converting enzyme 2;ethnic variation;gene expression;molecular dynamics simulation
Journal Article;Research Support, Non-U.S. Gov't
Li, Quan;Cao, Zanxia;Rahman, Proton
10.1002/mgg3.1344
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Genetic variability of human angiotensin-converting enzyme 2 (hACE2) among various ethnic populations. [Abstract]: BACKGROUND: There appears to be large regional variation for susceptibility, severity, and mortality for COVID-19 infections. Numerous potential factors could explain the wide variability in the n...
32,875,925
J Drug Target
Active-site Molecular docking of Nigellidine with nucleocapsid- NSP2-MPro of COVID-19 and to human IL1R-IL6R and strong antioxidant role of Nigella-sativa in experimental rats.
The recent outbreak of SARS CoV-2 has changed the global scenario of human lives/economy. A significant number of the non-survivors showed cardiac-renal-vasculature dysfunction. A 'cytokine storm' namely, interleukin IL6-IL1 receptors i.e. IL6R-IL1R over-functioning was reported. Here, nigellidine, an indazole-alkaloid...
nigellidine;sars cov 2 proteins;cytokine;cytotoxicity test;inhibition;molecular docking;rat model
Journal Article
Maiti, Smarajit;Banerjee, Amrita;Nazmeen, Aarifa;Kanwar, Mehak;Das, Shilpa
10.1080/1061186X.2020.1817040
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Active-site Molecular docking of Nigellidine with nucleocapsid- NSP2-MPro of COVID-19 and to human IL1R-IL6R and strong antioxidant role of Nigella-sativa in experimental rats. [Abstract]: The recent outbreak of SARS CoV-2 has changed the global scenario of human lives/economy. A significant number of the non-...
32,452,816
J Med Internet Res
Digital Health Equity and COVID-19: The Innovation Curve Cannot Reinforce the Social Gradient of Health.
Digital health innovations have been rapidly implemented and scaled to provide solutions to health delivery challenges posed by the coronavirus disease (COVID-19) pandemic. This has provided people with ongoing access to vital health services while minimizing their potential exposure to infection and allowing them to m...
covid-19;digital determinants of health;digital health;digital health equity;ehealth;equity;public health;social;virtual health
Journal Article
Crawford, Allison;Serhal, Eva
10.2196/19361
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Digital Health Equity and COVID-19: The Innovation Curve Cannot Reinforce the Social Gradient of Health. [Abstract]: Digital health innovations have been rapidly implemented and scaled to provide solutions to health delivery challenges posed by the coronavirus disease (COVID-19) pandemic. This has provided peo...
32,836,444
Public Adm Rev
Fiscal Responses to COVID-19: Evidence from Local Governments and Nonprofits.
The rate of expansion and breadth of COVID-19 caught the world by surprise. From the perspective of nonprofit and public entities responsible for service provision, this pandemic is also unprecedented. We offer a RISE framework for navigating the fiscal effects of COVID-19 and rely on recent surveys to assess local gov...
covid-19;fiscal responses;public and nonprofit finance
Journal Article
Maher, Craig S;Hoang, Trang;Hindery, Anne
10.1111/puar.13238
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Fiscal Responses to COVID-19: Evidence from Local Governments and Nonprofits. [Abstract]: The rate of expansion and breadth of COVID-19 caught the world by surprise. From the perspective of nonprofit and public entities responsible for service provision, this pandemic is also unprecedented. We offer a RISE fra...
32,565,904
Ecancermedicalscience
Zambia's National Cancer Centre response to the COVID-19 pandemic-an opportunity for improved care.
The COVID-19 pandemic has overwhelmed health systems around the globe even in countries with strong economies. This is of particular concern for nations with weaker health systems. This article reports the response of a comprehensive cancer centre in a lower-middle income country to prevent COVID-19 transmission and ho...
covid-19;cancer centre preparedness
Journal Article
Lombe, Dorothy C;Mwaba, Catherine K;Msadabwe, Susan C;Banda, Lewis;Mwale, Maurice;Pupwe, George;Kamfwa, Paul;Kanduza, Mulape;Munkupa, Harry;Maliti, Biemba;Simbeye, Kalyoka;Hachizo, Pious;Lin, Lilie;Chiao, Elizabeth;Lishimpi, Kennedy
10.3332/ecancer.2020.1051
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Zambia's National Cancer Centre response to the COVID-19 pandemic-an opportunity for improved care. [Abstract]: The COVID-19 pandemic has overwhelmed health systems around the globe even in countries with strong economies. This is of particular concern for nations with weaker health systems. This article repor...
32,315,817
J Clin Virol
Prevalence and severity of corona virus disease 2019 (COVID-19): A systematic review and meta-analysis.
BACKGROUND: Since being first reported in Wuhan, China, in December 8, 2019, the outbreak of the novel coronavirus, now known as COVID-19, has spread globally. Some case studies regarding the characteristics and outcome of patients with COVID-19 have been published recently. We conducted a meta-analysis to evaluate the...
covid-19;comorbidities;mortality;severity;symptom
Journal Article;Meta-Analysis;Systematic Review
Hu, Yong;Sun, Jiazhong;Dai, Zhe;Deng, Haohua;Li, Xin;Huang, Qi;Wu, Yuwen;Sun, Li;Xu, Yancheng
10.1016/j.jcv.2020.104371
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Prevalence and severity of corona virus disease 2019 (COVID-19): A systematic review and meta-analysis. [Abstract]: BACKGROUND: Since being first reported in Wuhan, China, in December 8, 2019, the outbreak of the novel coronavirus, now known as COVID-19, has spread globally. Some case studies regarding the cha...
32,983,836
Int J Dyn Control
Modelling the influence of progressive social awareness, lockdown and anthropogenic migration on the dynamics of an epidemic.
The basic Susceptible-Infected-Recovered (SIR) model is extended to include effects of progressive social awareness, lockdowns and anthropogenic migration. It is found that social awareness can effectively contain the spread by lowering the basic reproduction rate R 0 . Interestingly, the awareness is found to be more ...
epidemic migration;mathematical model;susceptible-infected-recovered (sir)
Journal Article
Bhattacharyya, R;Konar, Partha
10.1007/s40435-020-00692-1
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Modelling the influence of progressive social awareness, lockdown and anthropogenic migration on the dynamics of an epidemic. [Abstract]: The basic Susceptible-Infected-Recovered (SIR) model is extended to include effects of progressive social awareness, lockdowns and anthropogenic migration. It is found that ...
32,536,759
Chaos Solitons Fractals
Application of deep learning for fast detection of COVID-19 in X-Rays using nCOVnet.
Presently, COVID-19 has posed a serious threat to researchers, scientists, health professionals, and administrations around the globe from its detection to its treatment. The whole world is witnessing a lockdown like situation because of COVID-19 pandemic. Persistent efforts are being made by the researchers to obtain ...
covid-19;convolutional neural network (cnn);deep learning;detection;x-rays;ncovnet
Journal Article
Panwar, Harsh;Gupta, P K;Siddiqui, Mohammad Khubeb;Morales-Menendez, Ruben;Singh, Vaishnavi
10.1016/j.chaos.2020.109944
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Application of deep learning for fast detection of COVID-19 in X-Rays using nCOVnet. [Abstract]: Presently, COVID-19 has posed a serious threat to researchers, scientists, health professionals, and administrations around the globe from its detection to its treatment. The whole world is witnessing a lockdown li...
32,742,969
Euroasian J Hepatogastroenterol
Treatment of COVID-19 Patients at a Medical College Hospital in Bangladesh.
Background and aim: Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has induced a sense of panic around the world as the disease is highly contagious and has been spreading in full swing during last 5 months causing millions of COVID-19 patients and hundreds ...
bangladesh;coronavirus disease 2019;therapy
Journal Article
Bhuyan, Muhammad Ar;Al Mahtab, Mamun;Ashab, Eshita;Haque, Md Jahirul;Hoque, Syed Md M;Faizul Huq, Akm;Islam, Md Atikul;Choudhury, Nuzhat;Alia, Reema A;Mahtab, Musarrat;Khan, Md Sakirul I;Akbar, Sheikh Mf
10.5005/jp-journals-10018-1317
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Treatment of COVID-19 Patients at a Medical College Hospital in Bangladesh. [Abstract]: Background and aim: Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has induced a sense of panic around the world as the disease is highly contagious and has been...
32,404,975
Bone Marrow Transplant
The challenge of COVID-19 and hematopoietic cell transplantation; EBMT recommendations for management of hematopoietic cell transplant recipients, their donors, and patients undergoing CAR T-cell therapy.
The new coronavirus SARS-CoV-2 has rapidly spread over the world causing the disease by WHO called COVID-19. This pandemic poses unprecedented stress on the health care system including programs performing allogeneic and autologous hematopoietic cell transplantation (HCT) and cellular therapy such as with CAR T cells. ...
Journal Article;Practice Guideline;Review
Ljungman, Per;Mikulska, Malgorzata;de la Camara, Rafael;Basak, Grzegorz W;Chabannon, Christian;Corbacioglu, Selim;Duarte, Rafael;Dolstra, Harry;Lankester, Arjan C;Mohty, Mohamad;Montoto, Silvia;Murray, John;Peffault de Latour, Regis;Snowden, John A;Yakoub-Agha, Ibrahim;Verhoeven, Bregje;Kroger, Nicolaus;Styczynski, Jan
10.1038/s41409-020-0919-0
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The challenge of COVID-19 and hematopoietic cell transplantation; EBMT recommendations for management of hematopoietic cell transplant recipients, their donors, and patients undergoing CAR T-cell therapy. [Abstract]: The new coronavirus SARS-CoV-2 has rapidly spread over the world causing the disease by WHO ca...
32,665,041
Trials
Breath Regulation and yogic Exercise An online Therapy for calm and Happiness (BREATH) for frontline hospital and long-term care home staff managing the COVID-19 pandemic: A structured summary of a study protocol for a feasibility study for a randomised controlled trial.
OBJECTIVES: Objective 1: To determine if it is feasible to conduct an RCT of online Sudarshan Kriya Yoga (SKY) for frontline hospital and long-term care home staff under the constraints imposed by the COVID-19 pandemic and need for remote trial monitoring. Objective 2: To assess whether online versions of SKY and/or He...
covid-19;healthcare staff;randomised controlled trial;work stress;mind-body intervention;protocol;resiliency;yoga
Clinical Trial Protocol;Clinical Trial, Phase I;Clinical Trial, Phase II;Letter
Lai, Ka Sing Paris;Watt, Christine;Ionson, Emily;Baruss, Imants;Forchuk, Cheryl;Sukhera, Javeed;Burhan, Amer M;Vasudev, Akshya
10.1186/s13063-020-04583-w
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Breath Regulation and yogic Exercise An online Therapy for calm and Happiness (BREATH) for frontline hospital and long-term care home staff managing the COVID-19 pandemic: A structured summary of a study protocol for a feasibility study for a randomised controlled trial. [Abstract]: OBJECTIVES: Objective 1: To...
32,461,973
Biomed Res Int
Design of a Multiepitope-Based Peptide Vaccine against the E Protein of Human COVID-19: An Immunoinformatics Approach.
Background: A new endemic disease has spread across Wuhan City, China, in December 2019. Within few weeks, the World Health Organization (WHO) announced a novel coronavirus designated as coronavirus disease 2019 (COVID-19). In late January 2020, WHO declared the outbreak of a "public-health emergency of international c...
Journal Article
Abdelmageed, Miyssa I;Abdelmoneim, Abdelrahman H;Mustafa, Mujahed I;Elfadol, Nafisa M;Murshed, Naseem S;Shantier, Shaza W;Makhawi, Abdelrafie M
10.1155/2020/2683286
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Design of a Multiepitope-Based Peptide Vaccine against the E Protein of Human COVID-19: An Immunoinformatics Approach. [Abstract]: Background: A new endemic disease has spread across Wuhan City, China, in December 2019. Within few weeks, the World Health Organization (WHO) announced a novel coronavirus designa...
32,835,018
Interdiscip Neurosurg
Targeting of renin-angiotensin system in COVID-19 patients affected by stroke: Emerging concerns about detrimental vs. benefit effect.
Objective: The present short report summarizes some clinical characteristics of six patients affected by stroke while being on angiotensin-converting enzyme (ACE)2 inhibitors and angiotensin II receptor blockers (ARBs) before and during COVID-19. Methods: Medical charts and images of six patients affected by stroke whi...
ace inhibitors;angiotensin ii receptor blockers;covid-19;renin-angiotensin system;sars-cov-2;stroke
Journal Article
Luzzi, Sabino;Giotta Lucifero, Alice;Marasco, Stefano;Del Maestro, Mattia;Bellantoni, Giuseppe;Gragnaniello, Cristian
10.1016/j.inat.2020.100822
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Targeting of renin-angiotensin system in COVID-19 patients affected by stroke: Emerging concerns about detrimental vs. benefit effect. [Abstract]: Objective: The present short report summarizes some clinical characteristics of six patients affected by stroke while being on angiotensin-converting enzyme (ACE)2 ...
32,231,345
Cell Res
Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion.
The recent outbreak of coronavirus disease (COVID-19) caused by SARS-CoV-2 infection in Wuhan, China has posed a serious threat to global public health. To develop specific anti-coronavirus therapeutics and prophylactics, the molecular mechanism that underlies viral infection must first be defined. Therefore, we herein...
Journal Article
Xia, Shuai;Liu, Meiqin;Wang, Chao;Xu, Wei;Lan, Qiaoshuai;Feng, Siliang;Qi, Feifei;Bao, Linlin;Du, Lanying;Liu, Shuwen;Qin, Chuan;Sun, Fei;Shi, Zhengli;Zhu, Yun;Jiang, Shibo;Lu, Lu
10.1038/s41422-020-0305-x
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion. [Abstract]: The recent outbreak of coronavirus disease (COVID-19) caused by SARS-CoV-2 infection in Wuhan, China has...
32,963,442
Indian J Crit Care Med
Past, Present, and Future of Remdesivir: An Overview of the Antiviral in Recent Times.
In the current COVID-19 pandemic, evidence to justify the use of any specific antiviral drug with proven efficacy is not yet available. Antiviral drug development always remains a challenge to the scientists. Remdesivir has emerged as a promising molecule, based on results of clinical trials and observational studies a...
covid-19 drug treatment;clinical trials;viral genome
Journal Article;Review
Choudhury, Shouvik;Chakraborty, Dwaipayan S;Lahiry, Sandeep;Chatterjee, Suparna
10.5005/jp-journals-10071-23491
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Past, Present, and Future of Remdesivir: An Overview of the Antiviral in Recent Times. [Abstract]: In the current COVID-19 pandemic, evidence to justify the use of any specific antiviral drug with proven efficacy is not yet available. Antiviral drug development always remains a challenge to the scientists. Rem...
32,317,402
J Am Soc Nephrol
Early Description of Coronavirus 2019 Disease in Kidney Transplant Recipients in New York.
BACKGROUND: The novel SARS-CoV-2 virus has caused a global pandemic of coronavirus disease 2019 (COVID-19). Although immunosuppressed individuals are thought to be at an increased risk of severe disease, little is known about their clinical presentation, disease course, or outcomes. METHODS: We report 15 kidney transpl...
covid-19;epidemiology and outcomes;kidney transplantation;transplant outcomes
Journal Article
10.1681/ASN.2020030375
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Early Description of Coronavirus 2019 Disease in Kidney Transplant Recipients in New York. [Abstract]: BACKGROUND: The novel SARS-CoV-2 virus has caused a global pandemic of coronavirus disease 2019 (COVID-19). Although immunosuppressed individuals are thought to be at an increased risk of severe disease, litt...
32,924,825
J Biomol Struct Dyn
Computational insight of dexamethasone against potential targets of SARS-CoV-2.
The health sector has been on the race to find a potent therapy for coronavirus disease (COVID)-19, a diseases caused by severe acute respiratory syndrome coronavirus (SARS-CoV)-2. Repurposed anti-viral drugs have played a huge role in combating the virus, and most recently, dexamethasone (Dex) have shown its therapeut...
covid-19;dexamethasone;sars-cov-2;glucocorticoid;interleukins;main protease
Journal Article
Fadaka, Adewale Oluwaseun;Sibuyi, Nicole Remaliah Samantha;Madiehe, Abram Madimabe;Meyer, Mervin
10.1080/07391102.2020.1819880
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Computational insight of dexamethasone against potential targets of SARS-CoV-2. [Abstract]: The health sector has been on the race to find a potent therapy for coronavirus disease (COVID)-19, a diseases caused by severe acute respiratory syndrome coronavirus (SARS-CoV)-2. Repurposed anti-viral drugs have playe...
32,730,199
Prev Chronic Dis
Pharmacist-Led Chronic Care Management for Medically Underserved Rural Populations in Florida During the COVID-19 Pandemic.
Medically underserved patients in rural areas are more vulnerable to poor health outcomes, including the risks associated with coronavirus disease 2019 (COVID-19). Pharmacists, student pharmacists, and other health care professionals are working together to implement new, innovative ways to deliver the same standard of...
Journal Article
Como, Madison;Carter, Chenita White;Larose-Pierre, Margareth;O'Dare, Kellie;Hall, Cynthia R;Mobley, Jason;Robertson, Gervin;Leonard, Jason;Tew, Lindsey
10.5888/pcd17.200265
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Pharmacist-Led Chronic Care Management for Medically Underserved Rural Populations in Florida During the COVID-19 Pandemic. [Abstract]: Medically underserved patients in rural areas are more vulnerable to poor health outcomes, including the risks associated with coronavirus disease 2019 (COVID-19). Pharmacists...
32,928,499
Cir Esp
Influence of the lockdown due to COVID-19 on ponderal results during the first year after vertical gastrectomy.
INTRODUCTION: COVID-19 pandemic has lead to lockdown of population in many countries. In Spain, the state of alarm was established from March 15 to June 20, 2020. Usually this fact decreased people's mobility and physical activity, in addition to producing or exacerbating psychological disorders. Our aim was to determi...
bariatric surgery;covid-19;cirugia bariatrica;confinamiento;gastrectomia vertical;lockdown;manga gastrica;resultados;results;sleeve gastrectomy;vertical gastrectomy
Journal Article
Ruiz de Angulo, David;Balaguer Roman, Andres;Munitiz Ruiz, Vicente;Gil Vazquez, Pedro Jose;Ruiz Merino, Guadalupe;Ortiz Escandell, M Angeles;Martinez de Haro, Luisa F;Parrilla Paricio, Pascual
10.1016/j.ciresp.2020.08.003
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Influence of the lockdown due to COVID-19 on ponderal results during the first year after vertical gastrectomy. [Abstract]: INTRODUCTION: COVID-19 pandemic has lead to lockdown of population in many countries. In Spain, the state of alarm was established from March 15 to June 20, 2020. Usually this fact decrea...
32,742,564
World J Stem Cells
Stem cell therapy for COVID-19 and other respiratory diseases: Global trends of clinical trials.
Respiratory diseases, including coronavirus disease 2019 and chronic obstructive pulmonary disease (COPD), are leading causes of global fatality. There are no effective and curative treatments, but supportive care only. Cell therapy is a promising therapeutic strategy for refractory and unmanageable pulmonary illnesses...
covid-19;cell therapy;clinical trial;exosomes;pulmonary diseases
Journal Article;Review
Ji, Hong-Long;Liu, Cong;Zhao, Run-Zhen
10.4252/wjsc.v12.i6.471
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Stem cell therapy for COVID-19 and other respiratory diseases: Global trends of clinical trials. [Abstract]: Respiratory diseases, including coronavirus disease 2019 and chronic obstructive pulmonary disease (COPD), are leading causes of global fatality. There are no effective and curative treatments, but supp...