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32,805,321
Am J Infect Control
Impact of extended use and decontamination with vaporized hydrogen peroxide on N95 respirator fit.
BACKGROUND: To address the shortage of N95 respirators in the wake of the COVID-19 pandemic, some organizations have recommended the decontamination of respirators using vaporized hydrogen peroxide (VHP) sterilizer for up to 10 times. However, these recommendations are based on studies that did not take into account th...
covid-19;extended use respirators;filtering face respirators;fit test qualitative;reprocessing;reuse
Journal Article
Lieu, Anthony;Mah, Jordan;Zanichelli, Veronica;Exantus, Rose Carmel;Longtin, Yves
10.1016/j.ajic.2020.08.010
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Impact of extended use and decontamination with vaporized hydrogen peroxide on N95 respirator fit. [Abstract]: BACKGROUND: To address the shortage of N95 respirators in the wake of the COVID-19 pandemic, some organizations have recommended the decontamination of respirators using vaporized hydrogen peroxide (V...
32,773,613
Curr Opin Crit Care
Core outcomes sets for studies evaluating critical illness and patient recovery.
PURPOSE OF REVIEW: Given the growing body of critical care clinical research publications, core outcome sets (COSs) are important to help mitigate heterogeneity in outcomes assessed and measurement instruments used, and have potential to reduce research waste. This article provides an update on COS projects in critical...
Journal Article;Research Support, N.I.H., Extramural;Review
Dinglas, Victor D;Cherukuri, Sai P S;Needham, Dale M
10.1097/MCC.0000000000000750
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Core outcomes sets for studies evaluating critical illness and patient recovery. [Abstract]: PURPOSE OF REVIEW: Given the growing body of critical care clinical research publications, core outcome sets (COSs) are important to help mitigate heterogeneity in outcomes assessed and measurement instruments used, an...
32,711,256
EBioMedicine
Spatial and temporal dynamics of SARS-CoV-2 in COVID-19 patients: A systematic review and meta-analysis.
BACKGROUND: The spatial and temporal dynamics of SARS-CoV-2 have been described in case series and retrospective studies. In this study, we provide a coherent overview of the duration of viral detection and viral RNA load in COVID-19 patients, stratified by specimen type, clinical severity, and age. METHOD: We systemat...
covid-19;sars-cov-2;systematic review;viral dynamics
Journal Article;Meta-Analysis;Systematic Review
Weiss, Anne;Jellingso, Mads;Sommer, Morten Otto Alexander
10.1016/j.ebiom.2020.102916
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Spatial and temporal dynamics of SARS-CoV-2 in COVID-19 patients: A systematic review and meta-analysis. [Abstract]: BACKGROUND: The spatial and temporal dynamics of SARS-CoV-2 have been described in case series and retrospective studies. In this study, we provide a coherent overview of the duration of viral d...
32,835,148
Int J Surg Protoc
CRC COVID: Colorectal cancer services during COVID-19 pandemic. Study protocol for service evaluation.
Introduction: COVID-19 has had an impact on the provision of colorectal cancer care. The aim of the CRC COVID study is to describe the changes in colorectal cancer services in the UK and USA in response to the pandemic and to understand the long-term impact. Methods and analysis: This study comprises 4 phases. Phase 1 ...
covid-19;colorectal cancer;guidelines;service evaluation
Journal Article
Courtney, Alona;Howell, Ann-Marie;Daulatzai, Najib;Savva, Nicos;Warren, Oliver;Mills, Sarah;Rasheed, Shahnawaz;Milind, Goel;Tekkis, Nicholas;Gardiner, Matthew;Dai, Tinglong;Safar, Bashar;Efron, Jonathan E;Darzi, Ara;Tekkis, Paris;Kontovounisios, Christos
10.1016/j.isjp.2020.07.005
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: CRC COVID: Colorectal cancer services during COVID-19 pandemic. Study protocol for service evaluation. [Abstract]: Introduction: COVID-19 has had an impact on the provision of colorectal cancer care. The aim of the CRC COVID study is to describe the changes in colorectal cancer services in the UK and USA in re...
32,912,707
Arch Bronconeumol
COVID-19 and Smoking: A Systematic Review and Meta-Analysis of the Evidence.
OBJECTIVE: The aim of this study was to determine if tobacco use in patients with Covid-19 is associated with a negative disease course and adverse outcome, and if smoking, current and past, is associated with a greater possibility of developing COVID-19. MATERIAL AND METHODS: A systematic review (SR) and meta-analysis...
covid-19;meta-analysis;metaanalisis;odds ratio;revision sistematica;smoking;systematic review;tabaquismo
Journal Article;Systematic Review
Jimenez-Ruiz, Carlos A;Lopez-Padilla, Daniel;Alonso-Arroyo, Adolfo;Aleixandre-Benavent, Rafael;Solano-Reina, Segismundo;de Granda-Orive, Jose Ignacio
10.1016/j.arbres.2020.06.024
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: COVID-19 and Smoking: A Systematic Review and Meta-Analysis of the Evidence. [Abstract]: OBJECTIVE: The aim of this study was to determine if tobacco use in patients with Covid-19 is associated with a negative disease course and adverse outcome, and if smoking, current and past, is associated with a greater po...
32,831,151
Trials
Impact of Shenfu injection on a composite of organ dysfunction development in critically ill patients with coronavirus disease 2019 (COVID-19): A structured summary of a study protocol for a randomized controlled trial.
OBJECTIVES: This study aims to determine the protection provided by Shenfu injection (a traditional Chinese medicine) against development of organ dysfunction in critically ill patients with coronavirus disease 2019 (COVID-19). TRIAL DESIGN: This study is a multicenter, randomized, controlled, open-label, two-arm ratio...
covid-19;shenfu injection;protocol;randomised controlled trial
Clinical Trial Protocol;Letter;Multicenter Study;Randomized Controlled Trial
Wang, Zong-Yu;Fu, Shou-Zhi;Xu, Liang;Li, Shu-Sheng;Qian, Ke-Jian;He, Xian-Di;Zhu, Guo-Chao;Li, Liang-Hai;Zhang, Jun;Li, Wen-Fang;Qin, Bing-Yu;Zhou, Chen-Liang;Ma, Peng-Lin
10.1186/s13063-020-04677-5
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Impact of Shenfu injection on a composite of organ dysfunction development in critically ill patients with coronavirus disease 2019 (COVID-19): A structured summary of a study protocol for a randomized controlled trial. [Abstract]: OBJECTIVES: This study aims to determine the protection provided by Shenfu inje...
32,357,977
Clin Med (Lond)
Identifying rheumatic disease patients at high risk and requiring shielding during the COVID-19 pandemic.
Rheumatology teams care for patients with diverse, systemic autoimmune diseases who are often immunosuppressed and at high risk of infections. The current COVID-19 pandemic has presented particular challenges in caring for and managing this patient group. The office of the chief medical officer (CMO) for England contac...
covid-19;sars-cov-2;health economics;innovation;testing
Journal Article
Price, Elizabeth;MacPhie, Elizabeth;Kay, Lesley;Lanyon, Peter;Griffiths, Bridget;Holroyd, Christopher;Abhishek, Abhishek;Youngstein, Taryn;Bailey, Kathryn;Clinch, Jacqui;Shaikh, Muddassir;Rivett, Ali
10.7861/clinmed.2020-0160
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Identifying rheumatic disease patients at high risk and requiring shielding during the COVID-19 pandemic. [Abstract]: Rheumatology teams care for patients with diverse, systemic autoimmune diseases who are often immunosuppressed and at high risk of infections. The current COVID-19 pandemic has presented partic...
32,586,872
Microbiol Resour Announc
Genome Sequence of SARS-CoV-2 Isolate Cali-01, from Colombia, Obtained Using Oxford Nanopore MinION Sequencing.
We report the genome sequence of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) isolate obtained from a patient with symptoms of coronavirus disease 2019 (COVID-19) who was infected in Cali, Colombia. The patient had no recent travel record and did not require hospitalization. The virus genome was obtai...
Journal Article
Lopez-Alvarez, Diana;Parra, Beatriz;Cuellar, Wilmer J
10.1128/MRA.00573-20
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Genome Sequence of SARS-CoV-2 Isolate Cali-01, from Colombia, Obtained Using Oxford Nanopore MinION Sequencing. [Abstract]: We report the genome sequence of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) isolate obtained from a patient with symptoms of coronavirus disease 2019 (COVID-19) who wa...
32,766,569
Crit Care Explor
Treatment for Severe Coronavirus Disease 2019 With the Seraph-100 Microbind Affinity Blood Filter.
To determine whether Seraph-100 (Exthera Medical Corporation, Martinez, CA) treatment provides clinical benefit for severe coronavirus disease 2019 cases that require mechanical ventilation and vasopressor support. Data Sources: The first two patients in the United States treated with the novel Seraph-100 device. These...
seraph-100;coronavirus disease 2019;extracorporeal sorbent hemoperfusion;mechanical ventilation;severe acute respiratory syndrome coronavirus 2;vasopressor
Case Reports
Olson, Stephen W;Oliver, James D;Collen, Jacob;Bunin, Jessica;Gleeson, Todd D;Foster, Brian E;Simmons, Mark P;Chen, Hua W;Ficke, Jennifer B;Brown, Tara E;Nau, Mark T;Cebula, Brennan R;Kielstein, Jan;Chung, Kevin K
10.1097/CCE.0000000000000180
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Treatment for Severe Coronavirus Disease 2019 With the Seraph-100 Microbind Affinity Blood Filter. [Abstract]: To determine whether Seraph-100 (Exthera Medical Corporation, Martinez, CA) treatment provides clinical benefit for severe coronavirus disease 2019 cases that require mechanical ventilation and vasopr...
32,436,845
Diagn Interv Radiol
A review on the use of artificial intelligence for medical imaging of the lungs of patients with coronavirus disease 2019.
The results of research on the use of artificial intelligence (AI) for medical imaging of the lungs of patients with coronavirus disease 2019 (COVID-19) has been published in various forms. In this study, we reviewed the AI for diagnostic imaging of COVID-19 pneumonia. PubMed, arXiv, medRxiv, and Google scholar were us...
Journal Article;Review
Ito, Rintaro;Iwano, Shingo;Naganawa, Shinji
10.5152/dir.2019.20294
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: A review on the use of artificial intelligence for medical imaging of the lungs of patients with coronavirus disease 2019. [Abstract]: The results of research on the use of artificial intelligence (AI) for medical imaging of the lungs of patients with coronavirus disease 2019 (COVID-19) has been published in v...
32,328,220
Behav Anal Pract
A Proposed Process for Risk Mitigation During the COVID-19 Pandemic.
Recent executive orders have led some applied behavior analysis (ABA) providers to interpret themselves as "essential personnel" during the COVID-19 pandemic. In this article, we argue against a blanket interpretation that being labeled "essential personnel" means that all in-person ABA services for all clients should ...
autism;covid-19;decision making;essential services;ethics;pandemic
Journal Article;Review
Cox, David J;Plavnick, Joshua B;Brodhead, Matthew T
10.1007/s40617-020-00430-1
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: A Proposed Process for Risk Mitigation During the COVID-19 Pandemic. [Abstract]: Recent executive orders have led some applied behavior analysis (ABA) providers to interpret themselves as "essential personnel" during the COVID-19 pandemic. In this article, we argue against a blanket interpretation that being l...
32,299,206
Turk J Med Sci
Epidemiology of COVID-19
It seems that coronaviruses take an important place in the 21th century history. Five of seven human coronavirus was isolated in this century. Unfortunately, last three of them entered our life with a fear of outbreak, pandemic or death. Last human coronavirus which emerged world from Wuhan China, SARS CoV-2 and its cl...
covid-19;sars cov-2
Journal Article;Review
Bulut, Cemal;Kato, Yasuyuki
10.3906/sag-2004-172
[ 0, 0, 1, 0, 1, 0, 0 ]
[Title]: Epidemiology of COVID-19 [Abstract]: It seems that coronaviruses take an important place in the 21th century history. Five of seven human coronavirus was isolated in this century. Unfortunately, last three of them entered our life with a fear of outbreak, pandemic or death. Last human coronavirus which emerged...
32,311,350
Am J Obstet Gynecol
Coronavirus disease 2019 during pregnancy: a systematic review of reported cases.
OBJECTIVE: This study aimed to conduct a systematic review of the clinical outcomes reported for pregnant patients with coronavirus disease 2019. DATA SOURCES: The PubMed, CINAHL, and Scopus databases were searched using a combination of key words such as "Coronavirus and/or pregnancy," "COVID and/or pregnancy," "COVID...
covid-19;sars-cov-2;cesarean delivery;coronavirus pneumonia;fetal death;neonatal outcomes;preterm birth;stillbirth;vertical transmission novel coronavirus;viral pneumonia
Journal Article;Systematic Review;Video-Audio Media
Della Gatta, Anna Nunzia;Rizzo, Roberta;Pilu, Gianluigi;Simonazzi, Giuliana
10.1016/j.ajog.2020.04.013
[ 0, 0, 0, 0, 1, 0, 0 ]
[Title]: Coronavirus disease 2019 during pregnancy: a systematic review of reported cases. [Abstract]: OBJECTIVE: This study aimed to conduct a systematic review of the clinical outcomes reported for pregnant patients with coronavirus disease 2019. DATA SOURCES: The PubMed, CINAHL, and Scopus databases were searched us...
32,784,802
Biology (Basel)
Expression Profile of SARS-CoV-2 Host Receptors in Human Pancreatic Islets Revealed Upregulation of ACE2 in Diabetic Donors.
Cellular entry of SARS-CoV-2 is thought to occur through the binding of viral spike S1 protein to ACE2. The entry process involves priming of the S protein by TMPRSS2 and ADAM17, which collectively mediate the binding and promote ACE2 shedding. In this study, microarray and RNA-sequencing (RNA-seq) expression data were...
ace2;adam17;covid-19;diabetes;tmprss2;human islets
Journal Article
Taneera, Jalal;El-Huneidi, Waseem;Hamad, Mawieh;Mohammed, Abdul Khader;Elaraby, Esraa;Hachim, Mahmood Yaseen
10.3390/biology9080215
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Expression Profile of SARS-CoV-2 Host Receptors in Human Pancreatic Islets Revealed Upregulation of ACE2 in Diabetic Donors. [Abstract]: Cellular entry of SARS-CoV-2 is thought to occur through the binding of viral spike S1 protein to ACE2. The entry process involves priming of the S protein by TMPRSS2 and ADA...
33,008,959
Postgrad Med J
Experience of video consultation during the COVID-19 pandemic in elderly population for Parkinson's disease and movement disorders.
We have not been prepared for the current pandemic which has hit us hard. COVID-19, being a very contagious disease, one has to be very careful and diligent in caring for our patients keeping safety in mind all the time. For day-to-day care, new norms have been adopted for inpatient care. For outpatient care, the face-...
geriatric medicine;neurology;parkinson's disease
Journal Article
Kumar, Anil
10.1136/postgradmedj-2020-138846
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Experience of video consultation during the COVID-19 pandemic in elderly population for Parkinson's disease and movement disorders. [Abstract]: We have not been prepared for the current pandemic which has hit us hard. COVID-19, being a very contagious disease, one has to be very careful and diligent in caring ...
32,374,264
JMIR Public Health Surveill
Delivering Benefits at Speed Through Real-World Repurposing of Off-Patent Drugs: The COVID-19 Pandemic as a Case in Point.
Real-world drug repurposing-the immediate "off-label" prescribing of drugs to address urgent clinical needs-is a widely overlooked opportunity. Off-label prescribing (ie, for a nonapproved indication) is legal in most countries and tends to shift the burden of liability and cost to physicians and patients, respectively...
covid-19;crisis;drug costs;drug repositioning;drugs, generic;off-label use;pandemic;public health;severe acute respiratory syndrome coronavirus 2
Journal Article;Research Support, Non-U.S. Gov't
Rogosnitzky, Moshe;Berkowitz, Esther;Jadad, Alejandro R
10.2196/19199
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Delivering Benefits at Speed Through Real-World Repurposing of Off-Patent Drugs: The COVID-19 Pandemic as a Case in Point. [Abstract]: Real-world drug repurposing-the immediate "off-label" prescribing of drugs to address urgent clinical needs-is a widely overlooked opportunity. Off-label prescribing (ie, for a...
32,374,903
Int J Clin Pract
SARS-CoV-2 viral spike G614 mutation exhibits higher case fatality rate.
AIM: The COVID-19 pandemic is caused by infection with the SARS-CoV-2 virus. The major mutation detected to date in the SARS-CoV-2 viral envelope spike protein, which is responsible for virus attachment to the host and is also the main target for host antibodies, is a mutation of an aspartate (D) at position 614 found ...
Journal Article
Becerra-Flores, Manuel;Cardozo, Timothy
10.1111/ijcp.13525
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: SARS-CoV-2 viral spike G614 mutation exhibits higher case fatality rate. [Abstract]: AIM: The COVID-19 pandemic is caused by infection with the SARS-CoV-2 virus. The major mutation detected to date in the SARS-CoV-2 viral envelope spike protein, which is responsible for virus attachment to the host and is also...
32,702,365
Clin Biochem
Comparison of serologic and molecular SARS-CoV 2 results in a large cohort in Southern Tuscany demonstrates a role for serologic testing to increase diagnostic sensitivity.
BACKGROUND: Since February 2020, Italian hospitals registered COVID-19 (COronaVIrus Disease 19) cases more often than the rest of the Europe. During this epidemic, health authorities requested swab tests, while seeking new patient paths. METHODS: A dual laboratory approach was evaluated, consisting of patient care repo...
asymptomatic patients;coronavirus disease 19;serological tests;swabs;symptomatic/paucisymptomaticpatients
Comparative Study;Journal Article
Pancrazzi, Alessandro;Magliocca, Pasqualino;Lorubbio, Maria;Vaggelli, Guendalina;Galano, Angelo;Mafucci, Manuela;Duranti, Diletta;Cortesi, Monica;Mazzeschi, Erica;Fabbroni, Sara;Viti, Gianluca;Tartaglia Polcini, Alessandro;Tripodo, Emanuela;Sanchini, Paola;Gervino, Silvana;Tacconi, Danilo;Dei, Simona;Mazzierli, Monica;...
10.1016/j.clinbiochem.2020.07.002
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Comparison of serologic and molecular SARS-CoV 2 results in a large cohort in Southern Tuscany demonstrates a role for serologic testing to increase diagnostic sensitivity. [Abstract]: BACKGROUND: Since February 2020, Italian hospitals registered COVID-19 (COronaVIrus Disease 19) cases more often than the rest...
32,835,427
Drug Alcohol Rev
The burden of alcohol on health care during COVID-19.
Alcohol's impact on global health is substantial and of a similar order of magnitude to that from COVID-19. Alcohol now also poses specific concerns, such as increased risk of severe lung infections, domestic violence, child abuse, depression and suicide. Its use is unlikely to aid physical distancing or other preventa...
covid-19;alcohol;healthcare;mortality;policy
Journal Article
Stockwell, Tim;Andreasson, Sven;Cherpitel, Cheryl;Chikritzhs, Tanya;Dangardt, Frida;Holder, Harold;Naimi, Timothy;Sherk, Adam
10.1111/dar.13143
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The burden of alcohol on health care during COVID-19. [Abstract]: Alcohol's impact on global health is substantial and of a similar order of magnitude to that from COVID-19. Alcohol now also poses specific concerns, such as increased risk of severe lung infections, domestic violence, child abuse, depression an...
33,051,517
Sci Rep
Nebulized ivermectin for COVID-19 and other respiratory diseases, a proof of concept, dose-ranging study in rats.
Ivermectin is a widely used antiparasitic drug with known efficacy against several single-strain RNA viruses. Recent data shows significant reduction of SARS-CoV-2 replication in vitro by ivermectin concentrations not achievable with safe doses orally. Inhaled therapy has been used with success for other antiparasitics...
Journal Article;Research Support, Non-U.S. Gov't
Chaccour, Carlos;Abizanda, Gloria;Irigoyen-Barrio, Angel;Casellas, Aina;Aldaz, Azucena;Martinez-Galan, Fernando;Hammann, Felix;Gil, Ana Gloria
10.1038/s41598-020-74084-y
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Nebulized ivermectin for COVID-19 and other respiratory diseases, a proof of concept, dose-ranging study in rats. [Abstract]: Ivermectin is a widely used antiparasitic drug with known efficacy against several single-strain RNA viruses. Recent data shows significant reduction of SARS-CoV-2 replication in vitro ...
32,839,725
Curr Med Res Pract
Knowledge, perception, and practices towards COVID-19 pandemic among general public of India: A cross-sectional online survey.
Background: The success of battle against COVID-19 depends on public adherence towards infection control measures, which is greatly affected by their knowledge, perception, and practices towards this infection. Aim: To assess the knowledge, perception, and practice towards COVID-19 among the general public of India. Ma...
covid-19;knowledge;perception;practice;public;sars-cov-2
Journal Article
Narayana, Goruntla;Pradeepkumar, Bhupalam;Ramaiah, Jinka Dasaratha;Jayasree, Thummala;Yadav, Dasari Laluprasad;Kumar, Bonala Kranthi
10.1016/j.cmrp.2020.07.013
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Knowledge, perception, and practices towards COVID-19 pandemic among general public of India: A cross-sectional online survey. [Abstract]: Background: The success of battle against COVID-19 depends on public adherence towards infection control measures, which is greatly affected by their knowledge, perception,...
32,909,060
Eur Arch Otorhinolaryngol
Anosmia: an evolution of our understanding of its importance in COVID-19 and what questions remain to be answered.
BACKGROUND: From the start of the pandemic, many European otolaryngologists observed an unprecendented number of anosmic patients. Early reports proposed that anosmia could be the first or even the only symptom of COVID-19 infection, prompting calls for self-isolation in affected patients. METHODS: In the present artic...
anosmia;covid-19;coronavirus;olfactory;smell
Journal Article;Review
Saussez, Sven;Lechien, Jerome R;Hopkins, Claire
10.1007/s00405-020-06285-0
[ 0, 1, 0, 1, 0, 0, 0 ]
[Title]: Anosmia: an evolution of our understanding of its importance in COVID-19 and what questions remain to be answered. [Abstract]: BACKGROUND: From the start of the pandemic, many European otolaryngologists observed an unprecendented number of anosmic patients. Early reports proposed that anosmia could be the firs...
32,693,650
Expert Rev Anti Infect Ther
Tocilizumab for patients with severe COVID-19: a retrospective, multi-center study.
BACKGROUND: Tocilizumab, an inhibitor of the interleukin-6 receptor, may decrease the inflammatory response and control the symptoms of severe coronavirus disease 2019 (COVID-19), but the evidence is scarce. METHODS: This retrospective study included patients with severe COVID-19 requiring oxygen therapy who received t...
covid-19;sars-cov-2;interleukin-6;therapy;tocilizumab
Journal Article;Multicenter Study;Research Support, Non-U.S. Gov't
Tomasiewicz, Krzysztof;Piekarska, Anna;Stempkowska-Rejek, Justyna;Serafinska, Sylwia;Gawkowska, Aleksandra;Parczewski, Milosz;Niscigorska-Olsen, Jolanta;Lapinski, Tadeusz W;Zarebska-Michaluk, Dorota;Kowalska, Justyna D;Horban, Andrzej;Flisiak, Robert
10.1080/14787210.2020.1800453
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Tocilizumab for patients with severe COVID-19: a retrospective, multi-center study. [Abstract]: BACKGROUND: Tocilizumab, an inhibitor of the interleukin-6 receptor, may decrease the inflammatory response and control the symptoms of severe coronavirus disease 2019 (COVID-19), but the evidence is scarce. METHODS...
32,805,123
Am Surg
Implications for Telemedicine for Surgery Patients After COVID-19: Survey of Patient and Provider Experiences.
INTRODUCTION: The coronavirus disease 2019 (COVID-19) pandemic has expanded the utilization of telemedicine in clinical practice to minimize potential risks to both patients and providers. We aim to describe the perception of telemedicine by both surgical patients and providers to understand the preferences for future ...
general surgery;social and electronic media;special topics;surgical quality
Journal Article
Zhu, Clara;Williamson, John;Lin, Andrew;Bush, Kathryn;Hakim, Abraham;Upadhyaya, Kirtan;Hunter, Krystal;Sensenig, Richard;Spitz, Francis;Atabek, Umur;Hong, Young Ki
10.1177/0003134820945196
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Implications for Telemedicine for Surgery Patients After COVID-19: Survey of Patient and Provider Experiences. [Abstract]: INTRODUCTION: The coronavirus disease 2019 (COVID-19) pandemic has expanded the utilization of telemedicine in clinical practice to minimize potential risks to both patients and providers....
32,974,019
SAGE Open Med
Neurological manifestations in COVID-19: A narrative review.
COVID-19, a respiratory viral infection, has affected more than 10 million individuals worldwide. Common symptoms include fever, dry cough, fatigue and shortness of breath. Some patients show neurological manifestations such as headache, dizziness, cerebrovascular disease, peripheral nerve and muscle symptoms and smell...
covid-19;guillain-barre syndrome;sars-cov-2;cerebrovascular disease;neurological manifestations;taste and smell impairments
Journal Article;Review
Rahman, Asma;Niloofa, Roshan;De Zoysa, Ishan M;Cooray, Akila D;Kariyawasam, Jayani;Seneviratne, Suranjith L
10.1177/2050312120957925
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: Neurological manifestations in COVID-19: A narrative review. [Abstract]: COVID-19, a respiratory viral infection, has affected more than 10 million individuals worldwide. Common symptoms include fever, dry cough, fatigue and shortness of breath. Some patients show neurological manifestations such as headache, ...
32,863,098
Patient Educ Couns
Examining persuasive message type to encourage staying at home during the COVID-19 pandemic and social lockdown: A randomized controlled study in Japan.
OBJECTIVE: Behavioral change is the only prevention against the COVID-19 pandemic until vaccines become available. This is the first study to examine the most persuasive message type in terms of narrator difference in encouraging people to stay at home during the COVID-19 pandemic and social lockdown. METHODS: Particip...
covid-19;health communication;novel coronavirus;persuasion;protection motivation theory;social lockdown
Journal Article
Okuhara, Tsuyoshi;Okada, Hiroko;Kiuchi, Takahiro
10.1016/j.pec.2020.08.016
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Examining persuasive message type to encourage staying at home during the COVID-19 pandemic and social lockdown: A randomized controlled study in Japan. [Abstract]: OBJECTIVE: Behavioral change is the only prevention against the COVID-19 pandemic until vaccines become available. This is the first study to exam...
32,800,858
Int J Infect Dis
Does gender influence clinical expression and disease outcomes in COVID-19? A systematic review and meta-analysis.
BACKGROUND: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV2) was characterized at the end of 2019, and soon spread around the world, generating a pandemic. It has been suggested that men are more severely affected by the viral disease (COVID-19) than women. OBJECTIVE: The aim of this systematic literature re...
covid-19;gender;meta-analysis;systematic review
Journal Article;Meta-Analysis;Systematic Review
Ortolan, Augusta;Lorenzin, Mariagrazia;Felicetti, Mara;Doria, Andrea;Ramonda, Roberta
10.1016/j.ijid.2020.07.076
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Does gender influence clinical expression and disease outcomes in COVID-19? A systematic review and meta-analysis. [Abstract]: BACKGROUND: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV2) was characterized at the end of 2019, and soon spread around the world, generating a pandemic. It has been sugge...
32,727,177
Zhonghua Jie He He Hu Xi Za Zhi
[Clinical characteristics and outcome of 64 patients with severe COVID-19].
Objective: To investigate the causes of death in patients with severe COVID-19. Methods: A retrospective analysis was performed on 64 patients with severe COVID-19 admitted to Wuhan Pulmonary Hospital from January 12, 2020 to February 28, 2020. There were 36 males and 28 females, aging from 44 to 85 years[median 68 (62...
covid-19;myocardial injury;prognosis;respiratory distress syndrome, adult;viral myocarditis
Journal Article
Zhu, Q;Zhang, W;Wang, Q;Liu, J H;Wu, C H;Luo, T;Peng, P
10.3760/cma.j.cn112147-20200308-00275
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: [Clinical characteristics and outcome of 64 patients with severe COVID-19]. [Abstract]: Objective: To investigate the causes of death in patients with severe COVID-19. Methods: A retrospective analysis was performed on 64 patients with severe COVID-19 admitted to Wuhan Pulmonary Hospital from January 12, 2020 ...
32,788,506
Tohoku J Exp Med
Coronavirus Disease 2019: Hematological Anomalies and Antithrombotic Therapy.
After the first cases of COVID-19 appeared in Wuhan, China at the end of 2019, the disease quickly become a pandemic that has seriously affected the economic and health systems in more than 200 countries and territories around the world. Although most patients have mild symptoms or are even asymptomatic, there are pati...
covid-19;antithrombotic therapy;biomarkers;hematological anomalies;thrombo-inflammation
Journal Article;Review
Ornelas-Ricardo, Diana;Jaloma-Cruz, Ana Rebeca
10.1620/tjem.251.327
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Coronavirus Disease 2019: Hematological Anomalies and Antithrombotic Therapy. [Abstract]: After the first cases of COVID-19 appeared in Wuhan, China at the end of 2019, the disease quickly become a pandemic that has seriously affected the economic and health systems in more than 200 countries and territories a...
32,702,822
Medicine (Baltimore)
Efficacy of integrative Traditional Chinese and Western medicine for the treatment of patients infected with 2019 novel coronavirus (COVID-19): A protocol for systematic review and meta analysis.
BACKGROUND: No specific anti-virus drugs or vaccines have been available for the treatment of COVID-19. Integrative traditional Chinese and western medicine has been proposed as a therapeutic option with substantial applications in China. This protocol is proposed for a systematic review and meta-analysis that aims to ...
Journal Article;Meta-Analysis;Systematic Review
Liu, Dan;You, Yanyan;Chen, Yunhui;Tang, Songqi
10.1097/MD.0000000000020781
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Efficacy of integrative Traditional Chinese and Western medicine for the treatment of patients infected with 2019 novel coronavirus (COVID-19): A protocol for systematic review and meta analysis. [Abstract]: BACKGROUND: No specific anti-virus drugs or vaccines have been available for the treatment of COVID-19....
32,747,425
Sci Transl Med
3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice.
Pathogenic coronaviruses are a major threat to global public health, as exemplified by severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV), and the newly emerged SARS-CoV-2, the causative agent of coronavirus disease 2019 (COVID-19). We describe herein the s...
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't;Research Support, U.S. Gov't, Non-P.H.S.
Rathnayake, Athri D;Zheng, Jian;Kim, Yunjeong;Perera, Krishani Dinali;Mackin, Samantha;Meyerholz, David K;Kashipathy, Maithri M;Battaile, Kevin P;Lovell, Scott;Perlman, Stanley;Groutas, William C;Chang, Kyeong-Ok
10.1126/scitranslmed.abc5332
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: 3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice. [Abstract]: Pathogenic coronaviruses are a major threat to global public health, as exemplified by severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome corona...
32,640,525
Pathogens
Molecular Aspects of COVID-19 Differential Pathogenesis.
In the absence of therapeutic interventions, and a possible vaccine candidate, the spread of COVID-19 disease and associated fatalities are on the rise. The high mutation frequency in the genomic material of these viruses supports their ability to adapt to new environments, resulting in an efficient alteration in tissu...
covid-19;sars-cov-2;cardio-metabolic disease;comorbidity;differential pathogenesis
Journal Article;Review
Rothan, Hussin A;Acharya, Arpan;Reid, St Patrick;Kumar, Mukesh;Byrareddy, Siddappa N
10.3390/pathogens9070538
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Molecular Aspects of COVID-19 Differential Pathogenesis. [Abstract]: In the absence of therapeutic interventions, and a possible vaccine candidate, the spread of COVID-19 disease and associated fatalities are on the rise. The high mutation frequency in the genomic material of these viruses supports their abili...
33,071,402
Int J Forecast
Comparing the accuracy of several network-based COVID-19 prediction algorithms.
Researchers from various scientific disciplines have attempted to forecast the spread of the Coronavirus Disease 2019 (COVID-19). The proposed epidemic prediction methods range from basic curve fitting methods and traffic interaction models to machine-learning approaches. If we combine all these approaches, we obtain t...
bayesian methods;epidemiology;forecast accuracy;machine learning methods;network inference;sir model;time series methods
Journal Article
Achterberg, Massimo A;Prasse, Bastian;Ma, Long;Trajanovski, Stojan;Kitsak, Maksim;Van Mieghem, Piet
10.1016/j.ijforecast.2020.10.001
[ 0, 0, 0, 0, 0, 1, 0 ]
[Title]: Comparing the accuracy of several network-based COVID-19 prediction algorithms. [Abstract]: Researchers from various scientific disciplines have attempted to forecast the spread of the Coronavirus Disease 2019 (COVID-19). The proposed epidemic prediction methods range from basic curve fitting methods and traff...
32,660,309
J Child Neurol
COVID-19: A Review for the Pediatric Neurologist.
Children are susceptible to infection with the novel coronavirus SARS-CoV-2. In this time of uncertainty, this review attempts to compile information that may be helpful to pediatric neurologists. This review consolidates current data on the disease associated with SARS-CoV-2, called COVID-19, and information from past...
covid-19;coronavirus;infectious disease;pediatric
Journal Article;Review
Christy, Alison
10.1177/0883073820939387
[ 1, 1, 0, 0, 1, 0, 0 ]
[Title]: COVID-19: A Review for the Pediatric Neurologist. [Abstract]: Children are susceptible to infection with the novel coronavirus SARS-CoV-2. In this time of uncertainty, this review attempts to compile information that may be helpful to pediatric neurologists. This review consolidates current data on the disease...
33,027,257
PLoS One
The Global Health Security Index is not predictive of coronavirus pandemic responses among Organization for Economic Cooperation and Development countries.
The ongoing COVID-19 pandemic has devastated many countries with ripple effects felt in various sectors of the global economy. In November 2019, the Global Health Security (GHS) Index was released as the first detailed assessment and benchmarking of 195 countries to prevent, detect, and respond to infectious disease th...
Journal Article;Research Support, N.I.H., Extramural
Abbey, Enoch J;Khalifa, Banda A A;Oduwole, Modupe O;Ayeh, Samuel K;Nudotor, Richard D;Salia, Emmanuella L;Lasisi, Oluwatobi;Bennett, Seth;Yusuf, Hasiya E;Agwu, Allison L;Karakousis, Petros C
10.1371/journal.pone.0239398
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The Global Health Security Index is not predictive of coronavirus pandemic responses among Organization for Economic Cooperation and Development countries. [Abstract]: The ongoing COVID-19 pandemic has devastated many countries with ripple effects felt in various sectors of the global economy. In November 2019...
32,656,312
Virusdisease
Statistical analysis and visualization of the potential cases of pandemic coronavirus.
A local outbreak of initially unknown cause pneumonia was detected in Wuhan (Hubei, China) in December 2019 and a novel coronavirus, the severe acute respiratory syndrome coronavirus 2, was quickly found to be causing it. Since then, the epidemic has spread to all of China's mainland provinces as well as 58 other count...
covid-19;coronavirus;statistical analysis;visual data analysis
Journal Article
Muthusami, R;Saritha, K
10.1007/s13337-020-00610-1
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Statistical analysis and visualization of the potential cases of pandemic coronavirus. [Abstract]: A local outbreak of initially unknown cause pneumonia was detected in Wuhan (Hubei, China) in December 2019 and a novel coronavirus, the severe acute respiratory syndrome coronavirus 2, was quickly found to be ca...
32,562,486
Eur Heart J
COVID-19 kills at home: the close relationship between the epidemic and the increase of out-of-hospital cardiac arrests.
AIMS: An increase in out-of-hospital cardiac arrest (OHCA) incidence has been reported in the very early phase of the COVID-19 epidemic, but a clear demonstration of a correlation between the increased incidence of OHCA and COVID-19 is missing so far. We aimed to verify whether there is an association between the OHCA ...
covid-19;italy;out-of-hospital cardiac arrest;sars-cov-2
Journal Article;Multicenter Study;Research Support, Non-U.S. Gov't
Baldi, Enrico;Sechi, Giuseppe Maria;Mare, Claudio;Canevari, Fabrizio;Brancaglione, Antonella;Primi, Roberto;Klersy, Catherine;Palo, Alessandra;Contri, Enrico;Ronchi, Vincenza;Beretta, Giorgio;Reali, Francesca;Parogni, Pierpaolo;Facchin, Fabio;Rizzi, Ugo;Bussi, Daniele;Ruggeri, Simone;Oltrona Visconti, Luigi;Savastano, ...
10.1093/eurheartj/ehaa508
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 kills at home: the close relationship between the epidemic and the increase of out-of-hospital cardiac arrests. [Abstract]: AIMS: An increase in out-of-hospital cardiac arrest (OHCA) incidence has been reported in the very early phase of the COVID-19 epidemic, but a clear demonstration of a correlatio...
32,493,626
Arch Med Res
S1 Subunit and Host Proteases as Potential Therapeutic Avenues for the Treatment of COVID-19.
The novel corona virus (SARS-CoV-2) that causes severe acute respiratory syndrome, now called COVID-19 initially originated in Wuhan city of China and later spread across borders and infected more than five million people and killed over 3.4 lakh people all over the globe. This disease has been announced as pandemic by...
covid-19;s1 subunit;sars-cov-2;spike (s) transmembrane glycoprotein
Journal Article;Research Support, Non-U.S. Gov't;Review
Arafah, Azher;Ali, Shafat;Yatoo, Ali Mohd;Ali, Md Niamat;Rehman, Muneeb U
10.1016/j.arcmed.2020.05.013
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: S1 Subunit and Host Proteases as Potential Therapeutic Avenues for the Treatment of COVID-19. [Abstract]: The novel corona virus (SARS-CoV-2) that causes severe acute respiratory syndrome, now called COVID-19 initially originated in Wuhan city of China and later spread across borders and infected more than fiv...
32,712,300
Life Sci
The interaction of RAAS inhibitors with COVID-19: Current progress, perspective and future.
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is currently defined as the worst pandemic disease. SARS-CoV-2 infects human cells via the binding of its S protein to the receptor angiotensin-converting enzyme (ACE2). The use of ACEIs/ARBs (RAAS inhibitors) r...
ace2;covid-19;raas inhibitor;sars-cov-2
Journal Article;Review
Zhang, Jishou;Wang, Menglong;Ding, Wen;Wan, Jun
10.1016/j.lfs.2020.118142
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: The interaction of RAAS inhibitors with COVID-19: Current progress, perspective and future. [Abstract]: Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is currently defined as the worst pandemic disease. SARS-CoV-2 infects human cells via the binding...
32,806,708
Viruses
Of Mice and Men: The Coronavirus MHV and Mouse Models as a Translational Approach to Understand SARS-CoV-2.
The fatal acute respiratory coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Since COVID-19 was declared a pandemic by the World Health Organization in March 2020, infection and mortality rates have been rising steadily worldwide. The lack of a vaccine, as w...
covid-19;sars-cov-2;mouse hepatitis virus (mhv);viral infection
Journal Article;Review
Korner, Robert W;Majjouti, Mohamed;Alcazar, Miguel A Alejandre;Mahabir, Esther
10.3390/v12080880
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Of Mice and Men: The Coronavirus MHV and Mouse Models as a Translational Approach to Understand SARS-CoV-2. [Abstract]: The fatal acute respiratory coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Since COVID-19 was declared a pandemic by the World ...
33,007,942
Int J Environ Res Public Health
Encouraging and Enabling Lifestyles and Behaviours to Simultaneously Promote Environmental Sustainability, Health and Equity: Key Policy Messages from INHERIT.
Human consumption and activity are damaging the global ecosystem and the resources on which we rely for health, well-being and survival. The COVID-19 crisis is yet another manifestation of the urgent need to transition to more sustainable societies, further exposing the weaknesses in health systems and the injustice in...
behaviour change;environment;equity;health;health equity;intersectoral cooperation;policy;sustainable development;systemic change
Journal Article;Research Support, Non-U.S. Gov't;Review
Stegeman, Ingrid;Godfrey, Alba;Romeo-Velilla, Maria;Bell, Ruth;Staatsen, Brigit;van der Vliet, Nina;Kruize, Hanneke;Morris, George;Taylor, Timothy;Strube, Rosa;Anthun, Kirsti;Lillefjell, Monica;Zverinova, Iva;Scasny, Milan;Maca, Vojtech;Costongs, Caroline
10.3390/ijerph17197166
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Encouraging and Enabling Lifestyles and Behaviours to Simultaneously Promote Environmental Sustainability, Health and Equity: Key Policy Messages from INHERIT. [Abstract]: Human consumption and activity are damaging the global ecosystem and the resources on which we rely for health, well-being and survival. Th...
32,518,108
Proc Natl Acad Sci U S A
Universal vote-by-mail has no impact on partisan turnout or vote share.
In response to coronavirus disease 2019 (COVID-19), many scholars and policy makers are urging the United States to expand voting-by-mail programs to safeguard the electoral process. What are the effects of vote-by-mail? In this paper, we provide a comprehensive design-based analysis of the effect of universal vote-by-...
covid-19;elections;partisanship;vote-by-mail
Journal Article
Thompson, Daniel M;Wu, Jennifer A;Yoder, Jesse;Hall, Andrew B
10.1073/pnas.2007249117
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Universal vote-by-mail has no impact on partisan turnout or vote share. [Abstract]: In response to coronavirus disease 2019 (COVID-19), many scholars and policy makers are urging the United States to expand voting-by-mail programs to safeguard the electoral process. What are the effects of vote-by-mail? In thi...
32,800,622
Rev Esp Anestesiol Reanim
Patient characteristics, clinical course and factors associated to ICU mortality in critically ill patients infected with SARS-CoV-2 in Spain: A prospective, cohort, multicentre study.
BACKGROUND: The clinical course of COVID-19 critically ill patients, during their admission in the intensive care unit (UCI), including medical and infectious complications and support therapies, as well as their association with in-ICU mortality has not been fully reported. OBJECTIVE: This study aimed to describe clin...
Journal Article;Multicenter Study;Observational Study
Ferrando, C;Mellado-Artigas, R;Gea, A;Arruti, E;Aldecoa, C;Bordell, A;Adalia, R;Zattera, L;Ramasco, F;Monedero, P;Maseda, E;Martinez, A;Tamayo, G;Mercadal, J;Munoz, G;Jacas, A;Angeles, G;Castro, P;Hernandez-Tejero, M;Fernandez, J;Gomez-Rojo, M;Candela, A;Ripolles, J;Nieto, A;Bassas, E;Deiros, C;Margarit, A;Redondo, F J...
10.1016/j.redar.2020.07.003
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Patient characteristics, clinical course and factors associated to ICU mortality in critically ill patients infected with SARS-CoV-2 in Spain: A prospective, cohort, multicentre study. [Abstract]: BACKGROUND: The clinical course of COVID-19 critically ill patients, during their admission in the intensive care ...
32,833,671
Aging (Albany NY)
Clinical course and characteristics of patients with coronavirus disease 2019 in Wuhan, China: a single-centered, retrospective, observational study.
BACKGROUND: Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) is the virus responsible for the coronavirus disease 2019(COVID-19) pandemic. Despite the extensive studies aiming to understand the pathology of COVID-19, the clinicopathological characteristics and risk factors associated with COVID-19 remain mos...
covid-19;sars-cov-2;chronic diseases;infection;risk factors
Journal Article;Observational Study;Research Support, Non-U.S. Gov't
Liu, Yanfang;Liu, Lina;Wang, Ye;Du, Xinyang;Ma, Hong;Yao, Jing
10.18632/aging.103745
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical course and characteristics of patients with coronavirus disease 2019 in Wuhan, China: a single-centered, retrospective, observational study. [Abstract]: BACKGROUND: Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) is the virus responsible for the coronavirus disease 2019(COVID-19) pandemic....
32,684,499
Vaccine
Planning for COVID-19 vaccines safety surveillance.
COVID-19 vaccines are the most important tool to stem the pandemic. They are being developed with unprecedented global collaboration and accelerated timelines to achieve WHO Emergency Use Listing, while using regulatory pathways through national regulatory authorities. Alongside preparations to ensure equitable access ...
adverse event following immunization (aefi);adverse event of special interest (aesi);cepi;covid-19;clinical research;coronavirus;epidemic;global vaccine safety blueprint;outbreak;pandemic;sars-cov-2;safety;severe acute respiratory syndrome coronavirus 2;surveillance;vaccines;who
Journal Article;Research Support, Non-U.S. Gov't
Kochhar, Sonali;Salmon, Daniel A
10.1016/j.vaccine.2020.07.013
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Planning for COVID-19 vaccines safety surveillance. [Abstract]: COVID-19 vaccines are the most important tool to stem the pandemic. They are being developed with unprecedented global collaboration and accelerated timelines to achieve WHO Emergency Use Listing, while using regulatory pathways through national r...
32,611,913
Indian J Med Res
National sero-surveillance to monitor the trend of SARS-CoV-2 infection transmission in India: Protocol for community-based surveillance.
Conducting population-based serosurveillance for severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) will estimate and monitor the trend of infection in the adult general population, determine the socio-demographic risk factors and delineate the geographical spread of the infection. For this purpose, a serial ...
antibody - covid-19 - hotspot - sars-cov-2 - serial cross-sectional - seroprevalence - surveillance - trend
Journal Article
Kumar, Muthusamy Santhosh;Bhatnagar, Tarun;Manickam, Ponnaiah;Kumar, V Saravana;Rade, Kiran;Shah, Naman;Kant, Shashi;Babu, Giridhara R;Zodpey, Sanjay;Girish Kumar, C P;Vivian Thangaraj, Jeromie Wesley;Chatterjee, Pranab;Kanungo, Suman;Pandey, Ravindra Mohan;Murhekar, Manoj;Singh, Sujeet K;Sarkar, Swarup;Muliyi, J P;Gan...
10.4103/ijmr.IJMR_1818_20
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: National sero-surveillance to monitor the trend of SARS-CoV-2 infection transmission in India: Protocol for community-based surveillance. [Abstract]: Conducting population-based serosurveillance for severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) will estimate and monitor the trend of infection in...
32,989,427
SN Compr Clin Med
Polymorphic Ventricular Tachycardia with a Normal QTc Interval in a Patient with COVID-19 and Fever: Case Report.
Arrhythmias or conduction system disease are not the most common manifestation of COVID-19 infection in patients requiring hospital admission. Torsade de pointes typically occurs in bursts of self-limiting episodes with symptoms of dizziness and syncope. However, it may occasionally progress to ventricular fibrillation...
arrhythmias;covid-19;polymorphic ventricular tachycardia;severe acute respiratory syndrome coronavirus-2;torsade de pointes
Journal Article
Babapoor-Farrokhran, Savalan;Port, Zachary;Wiener, Philip C;Amanullah, Aman;Mainigi, Sumeet K
10.1007/s42399-020-00531-6
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Polymorphic Ventricular Tachycardia with a Normal QTc Interval in a Patient with COVID-19 and Fever: Case Report. [Abstract]: Arrhythmias or conduction system disease are not the most common manifestation of COVID-19 infection in patients requiring hospital admission. Torsade de pointes typically occurs in bur...
32,522,830
J Clin Microbiol
Comparative Pathogenesis of Bovine and Porcine Respiratory Coronaviruses in the Animal Host Species and SARS-CoV-2 in Humans.
Discovery of bats with severe acute respiratory syndrome (SARS)-related coronaviruses (CoVs) raised the specter of potential future outbreaks of zoonotic SARS-CoV-like disease in humans, which largely went unheeded. Nevertheless, the novel SARS-CoV-2 of bat ancestral origin emerged to infect humans in Wuhan, China, in ...
covid-19;sars;sars-cov-2;animal coronaviruses;bovine respiratory coronavirus;pathogenesis;porcine respiratory coronavirus
Comparative Study;Journal Article;Review
Saif, Linda J;Jung, Kwonil
10.1128/JCM.01355-20
[ 0, 1, 0, 1, 1, 0, 0 ]
[Title]: Comparative Pathogenesis of Bovine and Porcine Respiratory Coronaviruses in the Animal Host Species and SARS-CoV-2 in Humans. [Abstract]: Discovery of bats with severe acute respiratory syndrome (SARS)-related coronaviruses (CoVs) raised the specter of potential future outbreaks of zoonotic SARS-CoV-like disea...
32,425,635
Int J Infect Dis
Management of a COVID-19 outbreak in a hotel in Tenerife, Spain.
Since the first accounts of SARS-CoV-2, authorities have encountered numerous unprecedented situations threatening public health. This rapid communication addresses events that led to the quarantining of a hotel in Tenerife, Spain and the effectiveness of the rapidly implemented control measures. In total, eight cases ...
covid-19;hotel;outbreak;outbreak control;quarantine;rapid response
Case Reports
Hoefer, Andreas;Pampaka, Despina;Rivas Wagner, Eva;Aleman Herrera, Araceli;Garcia-Ramos Alonso, Eduardo;Lopez-Perea, Noemi;Cano Portero, Rosa;Herrera-Leon, Laura;Herrera-Leon, Silvia;Nunez Gallo, Domingo
10.1016/j.ijid.2020.05.047
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Management of a COVID-19 outbreak in a hotel in Tenerife, Spain. [Abstract]: Since the first accounts of SARS-CoV-2, authorities have encountered numerous unprecedented situations threatening public health. This rapid communication addresses events that led to the quarantining of a hotel in Tenerife, Spain and...
32,527,346
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
[Effect of Xuebijing injection on inflammatory markers and disease outcome of coronavirus disease 2019].
OBJECTIVE: To observe the influence of Xuebijing injection on the inflammatory markers and prognosis of coronavirus disease 2019 (COVID-19) patients. METHODS: Sixty severe COVID-19 patients admitted to Changsha Public Health Treatment Center (North Hospital of the First Hospital of Changsha City) from January to March ...
Journal Article;Randomized Controlled Trial
Wen, Long;Zhou, Zhiguo;Jiang, Dixuan;Huang, Kang
10.3760/cma.j.cn121430-20200406-00386
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: [Effect of Xuebijing injection on inflammatory markers and disease outcome of coronavirus disease 2019]. [Abstract]: OBJECTIVE: To observe the influence of Xuebijing injection on the inflammatory markers and prognosis of coronavirus disease 2019 (COVID-19) patients. METHODS: Sixty severe COVID-19 patients admi...
32,532,596
Radiography (Lond)
COVID-19 in the radiology department: What radiographers need to know.
OBJECTIVES: The aim is to review current literature related to the diagnosis, management, and follow-up of suspected and confirmed Covid-19 cases. KEY FINDINGS: Medical Imaging plays an important auxiliary role in the diagnosis of Covid-19 patients, mainly those most seriously affected. Practice differs widely among di...
covid-19;ct;chest;guidelines;imaging;radiography
Journal Article;Research Support, Non-U.S. Gov't;Review
Stogiannos, N;Fotopoulos, D;Woznitza, N;Malamateniou, C
10.1016/j.radi.2020.05.012
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 in the radiology department: What radiographers need to know. [Abstract]: OBJECTIVES: The aim is to review current literature related to the diagnosis, management, and follow-up of suspected and confirmed Covid-19 cases. KEY FINDINGS: Medical Imaging plays an important auxiliary role in the diagnosis ...
32,901,732
Braz Oral Res
Knowledge about Coronavirus disease 19 (COVID-19) and its professional repercussions among Brazilian endodontists.
The aim of this study was to assess Brazilian endodontists' level of knowledge about the coronavirus disease (COVID-19) and examine its professional repercussions. The link to the online survey that was created for this study was shared with Brazilian endodontists through social networking applications. The questionnai...
Journal Article
Candeiro, George Taccio de Miranda;Gavini, Giulio;Vivan, Rodrigo Ricci;Carvalho, Bruna Marjorie Dias Frota;Duarte, Marco Antonio Hungaro;FeijAo, Camila Pontes;FeijAo, Camila Pontes
10.1590/1807-3107bor-2020.vol34.0117
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Knowledge about Coronavirus disease 19 (COVID-19) and its professional repercussions among Brazilian endodontists. [Abstract]: The aim of this study was to assess Brazilian endodontists' level of knowledge about the coronavirus disease (COVID-19) and examine its professional repercussions. The link to the onli...
32,849,654
Front Immunol
Overview of Immune Response During SARS-CoV-2 Infection: Lessons From the Past.
After the 1918 flu pandemic, the world is again facing a similar situation. However, the advancement in medical science has made it possible to identify that the novel infectious agent is from the coronavirus family. Rapid genome sequencing by various groups helped in identifying the structure and function of the virus...
covid-19;hla;mhc presentation;t cells;coronavirus;immune response;memory t cell
Journal Article;Research Support, Non-U.S. Gov't;Review
Shah, Vibhuti Kumar;Firmal, Priyanka;Alam, Aftab;Ganguly, Dipyaman;Chattopadhyay, Samit
10.3389/fimmu.2020.01949
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Overview of Immune Response During SARS-CoV-2 Infection: Lessons From the Past. [Abstract]: After the 1918 flu pandemic, the world is again facing a similar situation. However, the advancement in medical science has made it possible to identify that the novel infectious agent is from the coronavirus family. Ra...
33,061,507
Diabetes Metab Syndr Obes
Increased Metabolic Burden Among Blacks: A Putative Mechanism for Disparate COVID-19 Outcomes.
Mounting evidence shows a disproportionate COVID-19 burden among Blacks. Early findings indicate pre-existing metabolic burden (eg, obesity, hypertension and diabetes) as key drivers of COVID-19 severity. Since Blacks exhibit higher prevalence of metabolic burden, we examined the influence of metabolic syndrome on disp...
covid-19 burden;blacks;disparities;metabolic risk factors;metabolic syndrome
Journal Article;Review
Jean-Louis, Girardin;Turner, Arlener D;Jin, Peng;Liu, Mengling;Boutin-Foster, Carla;McFarlane, Samy I;Seixas, Azizi
10.2147/DMSO.S267952
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: Increased Metabolic Burden Among Blacks: A Putative Mechanism for Disparate COVID-19 Outcomes. [Abstract]: Mounting evidence shows a disproportionate COVID-19 burden among Blacks. Early findings indicate pre-existing metabolic burden (eg, obesity, hypertension and diabetes) as key drivers of COVID-19 severity....
33,051,393
Brain Nerve
[Important and Unresolved Aspects of Neuropathologic Analyses of COVID-19 Individuals].
The pathomechanisms of central nervous system disorders associated with COVID-19 remain unsolved. It is therefore imperative to carry out pathologic, virologic, and molecular analyses of the human brain tissue to understand the neurological manifestations of COVID-19. However, autopsy of COVID-19 poses challenges in te...
Journal Article
Takao, Masaki
10.11477/mf.1416201649
[ 0, 1, 0, 1, 0, 0, 0 ]
[Title]: [Important and Unresolved Aspects of Neuropathologic Analyses of COVID-19 Individuals]. [Abstract]: The pathomechanisms of central nervous system disorders associated with COVID-19 remain unsolved. It is therefore imperative to carry out pathologic, virologic, and molecular analyses of the human brain tissue t...
32,771,637
Int J Infect Dis
Possible intrauterine SARS-CoV-2 infection: Positive nucleic acid testing results and consecutive positive SARS-CoV-2-specific antibody levels within 50 days after birth.
Whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affects the fetus in utero is important to the well-being of the mother and neonate. We report the case of a full-term neonate born to a mother who developed symptoms of coronavirus disease 2019 (COVID-19) at 32 weeks of gestation. The placental patho...
antibody;covid-19;intrauterine infection;nucleic acid testing;placental pathology;sars-cov-2
Case Reports;Journal Article
Gao, Jinzhi;Hu, Xiaolin;Sun, Xuan;Luo, Xiaoping;Chen, Ling
10.1016/j.ijid.2020.07.063
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Possible intrauterine SARS-CoV-2 infection: Positive nucleic acid testing results and consecutive positive SARS-CoV-2-specific antibody levels within 50 days after birth. [Abstract]: Whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affects the fetus in utero is important to the well-being o...
32,852,276
J Med Internet Res
The Art of Surgery: Balancing Compassionate With Virtual Care.
The recent drive to include virtual care in surgical practice has been accelerated due to the COVID-19 pandemic. Many physicians feel that communicating via telehealth is unlike traditional methods of providing health care, and thus guidance on maintaining excellence in communication is necessary, especially as academi...
covid-19 and virtual care;bioethics;consent;medical education;medical ethics;privacy;surgery;surgical communication;telehealth;telehealth in surgery;video care in surgery;virtual care;virtual care in surgery
Journal Article
Nemetz, Elisheva Tamar Anne;Urbach, David Robert;Devon, Karen Michelle
10.2196/22417
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The Art of Surgery: Balancing Compassionate With Virtual Care. [Abstract]: The recent drive to include virtual care in surgical practice has been accelerated due to the COVID-19 pandemic. Many physicians feel that communicating via telehealth is unlike traditional methods of providing health care, and thus gui...
32,589,145
JMIR Public Health Surveill
General Model for COVID-19 Spreading With Consideration of Intercity Migration, Insufficient Testing, and Active Intervention: Modeling Study of Pandemic Progression in Japan and the United States.
BACKGROUND: The coronavirus disease (COVID-19) began to spread in mid-December 2019 from Wuhan, China, to most provinces in China and over 200 other countries through an active travel network. Limited by the ability of the country or city to perform tests, the officially reported number of confirmed cases is expected t...
covid-19;seicr model;effect of intervention;pandemic spreading;prediction
Journal Article;Research Support, Non-U.S. Gov't
Zhan, Choujun;Tse, Chi Kong;Lai, Zhikang;Chen, Xiaoyun;Mo, Mingshen
10.2196/18880
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: General Model for COVID-19 Spreading With Consideration of Intercity Migration, Insufficient Testing, and Active Intervention: Modeling Study of Pandemic Progression in Japan and the United States. [Abstract]: BACKGROUND: The coronavirus disease (COVID-19) began to spread in mid-December 2019 from Wuhan, China...
32,742,035
Bull World Health Organ
Variant analysis of SARS-CoV-2 genomes.
Objective: To analyse genome variants of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Methods: Between 1 February and 1 May 2020, we downloaded 10 022 SARS CoV-2 genomes from four databases. The genomes were from infected patients in 68 countries. We identified variants by extracting pairwise alignment...
Journal Article
Koyama, Takahiko;Platt, Daniel;Parida, Laxmi
10.2471/BLT.20.253591
[ 0, 0, 0, 1, 1, 0, 0 ]
[Title]: Variant analysis of SARS-CoV-2 genomes. [Abstract]: Objective: To analyse genome variants of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Methods: Between 1 February and 1 May 2020, we downloaded 10 022 SARS CoV-2 genomes from four databases. The genomes were from infected patients in 68 count...
32,336,959
Proc (Bayl Univ Med Cent)
SARS-CoV-2 (COVID-19) and intravascular volume management strategies in the critically ill.
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread across the globe, and millions of people may be affected. While knowledge regarding epidemiologic features and diagnostic tools of coronavirus disease 2019 (COVID-19) is rapidly evolving, uncertainties surrounding various aspects of it...
covid-19;congestion;sars-cov-2;critically ill;resuscitation
Journal Article;Review
Kazory, Amir;Ronco, Claudio;McCullough, Peter A
10.1080/08998280.2020.1754700
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: SARS-CoV-2 (COVID-19) and intravascular volume management strategies in the critically ill. [Abstract]: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread across the globe, and millions of people may be affected. While knowledge regarding epidemiologic features and diagnostic ...
32,890,139
Transplantation
COVID-19 Outcomes Among Solid Organ Transplant Recipients: A Case-control Study.
BACKGROUND: Solid organ transplant (SOT) recipients are considered to be "vulnerable" to COVID-19 infection due to immunosuppression. To date, there are no studies that compared the disease severity of COVID-19 in SOT recipients with nontransplant patients. METHODS: In this case-control study, we compared the outcomes ...
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Sharma, Pratima;Chen, Vincent;Fung, Christopher M;Troost, Jonathan P;Patel, Vaiibhav N;Combs, Michael;Norman, Silas;Garg, Puneet;Colvin, Monica;Aaronson, Keith;Sonnenday, Christopher J;Golob, Jonathan L;Somers, Emily C;Doshi, Mona M
10.1097/TP.0000000000003447
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: COVID-19 Outcomes Among Solid Organ Transplant Recipients: A Case-control Study. [Abstract]: BACKGROUND: Solid organ transplant (SOT) recipients are considered to be "vulnerable" to COVID-19 infection due to immunosuppression. To date, there are no studies that compared the disease severity of COVID-19 in SOT ...
32,247,320
Lancet
Fangcang shelter hospitals: a novel concept for responding to public health emergencies.
Fangcang shelter hospitals are a novel public health concept. They were implemented for the first time in China in February, 2020, to tackle the coronavirus disease 2019 (COVID-19) outbreak. The Fangcang shelter hospitals in China were large-scale, temporary hospitals, rapidly built by converting existing public venues...
Journal Article;Research Support, Non-U.S. Gov't;Review
Chen, Simiao;Zhang, Zongjiu;Yang, Juntao;Wang, Jian;Zhai, Xiaohui;Barnighausen, Till;Wang, Chen
10.1016/S0140-6736(20)30744-3
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Fangcang shelter hospitals: a novel concept for responding to public health emergencies. [Abstract]: Fangcang shelter hospitals are a novel public health concept. They were implemented for the first time in China in February, 2020, to tackle the coronavirus disease 2019 (COVID-19) outbreak. The Fangcang shelte...
32,841,275
PLoS One
Prevalence of pulmonary embolism in patients with COVID-19 pneumonia and high D-dimer values: A prospective study.
INTRODUCTION: Coronavirus disease 2019 (COVID-19) pneumonia is associated to systemic hyper-inflammation and abnormal coagulation profile. D-dimer elevation is particularly frequent, and values higher than 1mug/mL have been associated with disease severity and in-hospital mortality. Previous retrospective studies found...
Journal Article
Alonso-Fernandez, Alberto;Toledo-Pons, Nuria;Cosio, Borja G;Millan, Aina;Calvo, Nestor;Ramon, Luisa;de Mendoza, Sara Hermoso;Morell-Garcia, Daniel;Bauca-Rossello, Josep Miquel;Nunez, Belen;Pons, Jaume;Palmer, Juan A;Martin, Luisa;Penaranda, Maria;Pou, Joan A;Sauleda, Jaume;Sala-Llinas, Ernest
10.1371/journal.pone.0238216
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Prevalence of pulmonary embolism in patients with COVID-19 pneumonia and high D-dimer values: A prospective study. [Abstract]: INTRODUCTION: Coronavirus disease 2019 (COVID-19) pneumonia is associated to systemic hyper-inflammation and abnormal coagulation profile. D-dimer elevation is particularly frequent, a...
32,570,174
Stem Cell Res
SARS-CoV-2 infection and stem cells: Interaction and intervention.
The emergence of the novel severe acute respiratory coronavirus 2 (SARS-CoV-2) in China and its rapid national and international spread have created a global health emergency. The resemblance with SARS-CoV in spike protein suggests that SARS-CoV-2 employs spike-driven entry into angiotensin-converting enzyme 2 (ACE2)-e...
immunomodulation;infection;repair;severe acute respiratory coronavirus 2;stem cells
Journal Article;Review
Yu, Fenggang;Jia, Rufu;Tang, Yongyong;Liu, Jin;Wei, Benjie
10.1016/j.scr.2020.101859
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: SARS-CoV-2 infection and stem cells: Interaction and intervention. [Abstract]: The emergence of the novel severe acute respiratory coronavirus 2 (SARS-CoV-2) in China and its rapid national and international spread have created a global health emergency. The resemblance with SARS-CoV in spike protein suggests ...
32,612,712
Ther Adv Musculoskelet Dis
Impact of COVID-19 on orthopaedic care: a call for nonoperative management.
Background: Surgical specialties face unique challenges caused by SARS-COV-2 (COVID-19). These disruptions will call on clinicians to have greater consideration for non-operative treatment options to help manage patient symptoms and provide therapeutic care in lieu of the traditional surgical management course of actio...
covid-19;nonoperative treatment;pandemic;surgery
Journal Article;Review
Phillips, Mark R;Chang, Yaping;Zura, Robert D;Mehta, Samir;Giannoudis, Peter V;Nolte, Peter A;Bhandari, Mohit
10.1177/1759720X20934276
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Impact of COVID-19 on orthopaedic care: a call for nonoperative management. [Abstract]: Background: Surgical specialties face unique challenges caused by SARS-COV-2 (COVID-19). These disruptions will call on clinicians to have greater consideration for non-operative treatment options to help manage patient sym...
32,838,176
SN Compr Clin Med
Navigating the Diagnostics of COVID-19.
The recent outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) began in Hubei province, China, in December 2019 and has spread worldwide at an alarming rate. With over eight million individuals infected and exceeding 400,000 deaths globally, the necessity to develop fast and efficient diagnosti...
covid-19;diagnostic test;rt-pcr;sars-cov-2;serology
Journal Article;Review
Sanyaolu, Adekunle;Okorie, Chuku;Marinkovic, Aleksandra;Ayodele, Oladapo;Abbasi, Abu Fahad;Prakash, Stephanie;Ahmed, Miriam;Kayode, Damilare;Jaferi, Urooj;Haider, Nafees
10.1007/s42399-020-00408-8
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Navigating the Diagnostics of COVID-19. [Abstract]: The recent outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) began in Hubei province, China, in December 2019 and has spread worldwide at an alarming rate. With over eight million individuals infected and exceeding 400,000 deaths gl...
32,727,175
Zhonghua Jie He He Hu Xi Za Zhi
[Clinical characteristics and death risk factors of severe COVID-19].
Objective: To analyze the clinical features and death-related risk factors of COVID-19. Methods: We enrolled 891 COVID-19 patients admitted to the Affiliated Hospital of Jianghan University from December 2019 to February 2020, including 427 men and 464 women. Of the 891 cases, 582 were severe or critical, including 423...
covid-19;clinical characteristics;cohort studies;risk factors
Journal Article
Qin, W;Hu, B Z;Zhang, Z;Chen, S;Li, F J;Zhu, Z Y;Wang, X J;Liu, M;Li, C H
10.3760/cma.j.cn112147-20200320-00380
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: [Clinical characteristics and death risk factors of severe COVID-19]. [Abstract]: Objective: To analyze the clinical features and death-related risk factors of COVID-19. Methods: We enrolled 891 COVID-19 patients admitted to the Affiliated Hospital of Jianghan University from December 2019 to February 2020, in...
32,803,762
Cell Biochem Funct
Potential small-molecule drugs as available weapons to fight novel coronavirus (2019-nCoV): A review.
Since the new coronavirus known as 2019-nCoV (severe acute respiratory syndrome coronavirus 2, SARS-CoV-2) has widely spread in Wuhan, China, with severe pneumonia, scientists and physicians have made remarkable efforts to use various options such as monoclonal antibodies, peptides, vaccines, small-molecule drugs and i...
2019-ncov;infection;small-molecule drugs
Journal Article;Review
Rahimkhoei, Vahid;Jabbari, Nassrollah;Nourani, Aynaz;Sharifi, Sina;Akbari, Ali
10.1002/cbf.3576
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Potential small-molecule drugs as available weapons to fight novel coronavirus (2019-nCoV): A review. [Abstract]: Since the new coronavirus known as 2019-nCoV (severe acute respiratory syndrome coronavirus 2, SARS-CoV-2) has widely spread in Wuhan, China, with severe pneumonia, scientists and physicians have m...
32,932,848
Sensors (Basel)
What Features and Functions Are Desired in Telemedical Services Targeted at Polish Older Adults Delivered by Wearable Medical Devices?-Pre-COVID-19 Flashback.
The emerging wearable medical devices open up new opportunities for the provision of health services and promise to accelerate the development of novel telemedical services. The main objective of this study was to investigate the desirable features and applications of telemedical services for the Polish older adults de...
assisted living technologies;gerontechnology;health monitoring system;telemedical services;wearable
Journal Article
Kantoch, Eliasz;Kantoch, Anna
10.3390/s20185181
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: What Features and Functions Are Desired in Telemedical Services Targeted at Polish Older Adults Delivered by Wearable Medical Devices?-Pre-COVID-19 Flashback. [Abstract]: The emerging wearable medical devices open up new opportunities for the provision of health services and promise to accelerate the developme...
32,794,460
J Infect Dev Ctries
Tuberculosis and COVID-19: An overlapping situation during pandemic.
INTRODUCTION: The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the coronavirus disease 2019 (COVID-19). First COVID-19 case was detected in March, 10, 2020 in Turkey and as of May, 18, 2020 148,067 cases have been identified and 4096 citizens have died. Tuberculosis ...
covid-19;mycobacterium tuberculosis;pcr;sars-cov-2;tuberculosis
Journal Article
Can Sarinoglu, Rabia;Sili, Uluhan;Eryuksel, Emel;Olgun Yildizeli, Sehnaz;Cimsit, Cagatay;Karahasan Yagci, Aysegul
10.3855/jidc.13152
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Tuberculosis and COVID-19: An overlapping situation during pandemic. [Abstract]: INTRODUCTION: The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the coronavirus disease 2019 (COVID-19). First COVID-19 case was detected in March, 10, 2020 in Turkey and as of M...
32,907,334
J Proteome Res
Repurposing of FDA-Approved Toremifene to Treat COVID-19 by Blocking the Spike Glycoprotein and NSP14 of SARS-CoV-2.
The global pandemic of Coronavirus Disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to the death of more than 675,000 worldwide and over 150,000 in the United States alone. However, there are currently no approved effective pharmacotherapies for COVID-19. Here, we...
covid-19;sars-cov-2;drug repurposing;methyltransferase nonstructural protein 14 (nsp14);molecular docking;spike glycoprotein;toremifene
Journal Article;Research Support, N.I.H., Extramural
Martin, William R;Cheng, Feixiong
10.1021/acs.jproteome.0c00397
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Repurposing of FDA-Approved Toremifene to Treat COVID-19 by Blocking the Spike Glycoprotein and NSP14 of SARS-CoV-2. [Abstract]: The global pandemic of Coronavirus Disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to the death of more than 675,000 worldwid...
32,858,940
J Clin Med
Could Mesenchymal Stem Cell-Derived Exosomes Be a Therapeutic Option for Critically Ill COVID-19 Patients?
Coronavirus disease 2019 (COVID-19) is a pandemic viral disease originated in Wuhan, China, in December 2019, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The severe form of the disease is often associated with acute respiratory distress syndrome (ARDS), and most critically ill patients r...
covid-19;acute lung injury;acute myocardial injury;angiotensin-converting enzyme 2;anti-inflammation;coronavirus;immunomodulation;mesenchymal stem cell-derived exosomes
Journal Article;Review
Gardin, Chiara;Ferroni, Letizia;Chachques, Juan Carlos;Zavan, Barbara
10.3390/jcm9092762
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Could Mesenchymal Stem Cell-Derived Exosomes Be a Therapeutic Option for Critically Ill COVID-19 Patients? [Abstract]: Coronavirus disease 2019 (COVID-19) is a pandemic viral disease originated in Wuhan, China, in December 2019, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The se...
32,612,435
Eurasian J Med
Atypical Presentation of COVID-19: Acute Renal Failure.
Coronavirus disease (COVID-19) emerged in Wuhan, China, in December 2019 and rapidly became a global pandemic, with the number of confirmed infections worldwide reaching 1 million by the start of April 2020 and 3 million less than a month later. COVID-19 can be encountered with different clinical presentations. We pres...
acute renal failure;sars-cov-2;acute respiratuary distress syndrome
Journal Article
Kerget, Bugra;Akgun, Metin;Dogan, Nazim
10.5152/eurasianjmed.2020.20134
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Atypical Presentation of COVID-19: Acute Renal Failure. [Abstract]: Coronavirus disease (COVID-19) emerged in Wuhan, China, in December 2019 and rapidly became a global pandemic, with the number of confirmed infections worldwide reaching 1 million by the start of April 2020 and 3 million less than a month late...
32,766,462
Infect Dis Model
Generalized logistic growth modeling of the COVID-19 pandemic in Asia.
Several months into the ongoing novel coronavirus disease 2019 (COVID-19) pandemic, this work provides a simple and direct projection of the outbreak spreading potential and the pandemic cessation dates in Chinese mainland, Iran, the Philippines and Chinese Taiwan, using the generalized logistic model (GLM). The short-...
covid-19;epidemic modeling;forecasting;generalized logistic model;richards model;sars-cov-2
Journal Article
Aviv-Sharon, Elinor;Aharoni, Asaph
10.1016/j.idm.2020.07.003
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: Generalized logistic growth modeling of the COVID-19 pandemic in Asia. [Abstract]: Several months into the ongoing novel coronavirus disease 2019 (COVID-19) pandemic, this work provides a simple and direct projection of the outbreak spreading potential and the pandemic cessation dates in Chinese mainland, Iran...
32,401,079
Med Teach
Adapting to the impact of COVID-19: Sharing stories, sharing practice.
Health Professions' Educators (HPEs) and their learners have to adapt their educational provision to rapidly changing and uncertain circumstances linked to the COVID-19 pandemic. This paper reports on an AMEE-hosted webinar: Adapting to the impact of COVID-19: Sharing stories, sharing practice. Attended by over 500 col...
covid-19;assessment;change;innovation;pandemic;resilience;selection;teaching and learning;technology;workplace learning
Journal Article
Cleland, Jennifer;McKimm, Judy;Fuller, Richard;Taylor, David;Janczukowicz, Janusz;Gibbs, Trevor
10.1080/0142159X.2020.1757635
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Adapting to the impact of COVID-19: Sharing stories, sharing practice. [Abstract]: Health Professions' Educators (HPEs) and their learners have to adapt their educational provision to rapidly changing and uncertain circumstances linked to the COVID-19 pandemic. This paper reports on an AMEE-hosted webinar: Ada...
32,233,876
Can Assoc Radiol J
The Role of Emergency Radiology in COVID-19: From Preparedness to Diagnosis [Formula: see text].
Emergency trauma radiology, although a relatively new subspecialty of radiology, plays a critical role in both the diagnosis/triage of acutely ill patients, but even more important in providing leadership and taking the lead in the preparedness of imaging departments in dealing with novel highly infectious communicable...
covid-19;ct;mers;sars;emergency and trauma radiology;preparedness
Journal Article;Review
Nasir, Muhammad Umer;Roberts, James;Muller, Nestor L;Macri, Francesco;Mohammed, Mohammed F;Akhlaghpoor, Shahram;Parker, William;Eftekhari, Arash;Rezaei, Susan;Mayo, John;Nicolaou, Savvas
10.1177/0846537120916419
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: The Role of Emergency Radiology in COVID-19: From Preparedness to Diagnosis [Formula: see text]. [Abstract]: Emergency trauma radiology, although a relatively new subspecialty of radiology, plays a critical role in both the diagnosis/triage of acutely ill patients, but even more important in providing leadersh...
32,810,439
Cell
Elevated Calprotectin and Abnormal Myeloid Cell Subsets Discriminate Severe from Mild COVID-19.
Blood myeloid cells are known to be dysregulated in coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2. It is unknown whether the innate myeloid response differs with disease severity and whether markers of innate immunity discriminate high-risk patients. Thus, we performed high-dimensional flow cytometry and si...
covid-19;s100a8;s100a9;sars-cov-2;calprotectin;emergency myelopoiesis;monocyte subsets;neutrophils;type i interferon
Journal Article
Silvin, Aymeric;Chapuis, Nicolas;Dunsmore, Garett;Goubet, Anne-Gaelle;Dubuisson, Agathe;Derosa, Lisa;Almire, Carole;Henon, Clemence;Kosmider, Olivier;Droin, Nathalie;Rameau, Philippe;Catelain, Cyril;Alfaro, Alexia;Dussiau, Charles;Friedrich, Chloe;Sourdeau, Elise;Marin, Nathalie;Szwebel, Tali-Anne;Cantin, Delphine;Mout...
10.1016/j.cell.2020.08.002
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Elevated Calprotectin and Abnormal Myeloid Cell Subsets Discriminate Severe from Mild COVID-19. [Abstract]: Blood myeloid cells are known to be dysregulated in coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2. It is unknown whether the innate myeloid response differs with disease severity and whether ...
32,884,603
Genes Environ
Mutagenic, Genotoxic and Immunomodulatory effects of Hydroxychloroquine and Chloroquine: a review to evaluate its potential to use as a prophylactic drug against COVID-19.
Hydroxychloroquine (HCQ) and Chloroquine (CQ) are two anti-malarial drugs that are now being extensively used by front-line healthcare workers and other common people as a prophylactic drug against the Corona Virus Disease - 19 (COVID-19) in India and as well as in many parts of the world. While only a few in vitro stu...
covid-19;chloroquine;genotoxicity;hydroxychloroquine;immunomodulation, prophylactic use;mutagenicity
Journal Article;Review
Giri, Allan;Das, Ankita;Sarkar, Ajoy K;Giri, Ashok K
10.1186/s41021-020-00164-0
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Mutagenic, Genotoxic and Immunomodulatory effects of Hydroxychloroquine and Chloroquine: a review to evaluate its potential to use as a prophylactic drug against COVID-19. [Abstract]: Hydroxychloroquine (HCQ) and Chloroquine (CQ) are two anti-malarial drugs that are now being extensively used by front-line hea...
32,454,250
Int J Surg
Avoiding health worker infection and containing the coronavirus disease 2019 pandemic: Perspectives from the frontline in Wuhan.
Coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused great public concern worldwide due to its high rates of infectivity and pathogenicity. The Chinese government responded in a timely manner, alleviated the dilemma, achieved a huge victory and...
asymptomatic infection;covid-19;health worker infection;personal protective equipment;sars-cov-2
Journal Article;Review
Tang, Ling-Hua;Tang, Shan;Chen, Xiao-Liang;Zhang, Shi;Xiong, Yong;Chen, Rong;Li, Wei;Liu, Hui-Min;Xia, Zhong-Yuan;Meng, Qing-Tao
10.1016/j.ijsu.2020.05.060
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Avoiding health worker infection and containing the coronavirus disease 2019 pandemic: Perspectives from the frontline in Wuhan. [Abstract]: Coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused great public concern worldwide due to its...
32,574,293
Front Public Health
Comparison of Epidemiological Variations in COVID-19 Patients Inside and Outside of China-A Meta-Analysis.
The objective of this study is to compare the epidemiological variations in COVID-19 patients reported in studies from inside and outside of China. We selected COVID-19 observational studies from eight countries, including, China, Italy, Australia, Canada, Korea, Taiwan, Singapore, and the USA, comprising a total of 13...
2019-ncov;covid-19;epidemiological characteristics;meta-analysis;symptoms
Journal Article;Meta-Analysis;Systematic Review
Ahmed, Ali;Ali, Areeba;Hasan, Sana
10.3389/fpubh.2020.00193
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Comparison of Epidemiological Variations in COVID-19 Patients Inside and Outside of China-A Meta-Analysis. [Abstract]: The objective of this study is to compare the epidemiological variations in COVID-19 patients reported in studies from inside and outside of China. We selected COVID-19 observational studies f...
32,976,847
Am J Ophthalmol
Implications of Coronavirus Disease 2019 for Ophthalmologists.
PURPOSE: To describe and explain the implications of coronavirus disease 2019 (COVID-19) for ophthalmologists considering the rapid developments in our understanding of the virology, transmission, and ocular involvement. DESIGN: Evidence-based perspective. METHODS: Review and synthesis of pertinent literature. RESULTS:...
Journal Article
Danesh-Meyer, Helen V;McGhee, Charles N J
10.1016/j.ajo.2020.09.027
[ 0, 0, 1, 0, 1, 0, 0 ]
[Title]: Implications of Coronavirus Disease 2019 for Ophthalmologists. [Abstract]: PURPOSE: To describe and explain the implications of coronavirus disease 2019 (COVID-19) for ophthalmologists considering the rapid developments in our understanding of the virology, transmission, and ocular involvement. DESIGN: Evidenc...
33,057,382
PLoS One
Before and after case reporting: A comparison of the knowledge, attitude and practices of the Jordanian population towards COVID-19.
Coronavirus disease- 2019 (COVID-19) is an emerging contagious infectious disease. It is pandemic and has affected more than 21 million people and resulted in more than 750,000 deaths worldwide (https://www.worldometers.info/coronavirus/#countries; 14/08/20). Our research group initiated a study to ascertain the knowle...
Journal Article
Elayeh, Eman;Aleidi, Shereen M;Ya'acoub, Rawan;Haddadin, Randa N
10.1371/journal.pone.0240780
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Before and after case reporting: A comparison of the knowledge, attitude and practices of the Jordanian population towards COVID-19. [Abstract]: Coronavirus disease- 2019 (COVID-19) is an emerging contagious infectious disease. It is pandemic and has affected more than 21 million people and resulted in more th...
32,690,074
Trials
Efficacy of local budesonide therapy in the management of persistent hyposmia in COVID-19 patients without signs of severity: A structured summary of a study protocol for a randomised controlled trial.
OBJECTIVES: To assess the efficacy of local intranasal treatment with budesonide (nasal irrigation), in addition to olfactory rehabilitation, in the management of loss of smell in COVID-19 patients without signs of severity and with persistent hyposmia 30 days after the onset of symptoms. To search for an association b...
covid-19;mri;randomised controlled trial;budesonide;corticosteroid;dysgeusia;hyposmia;nasal irrigation;rotocol
Clinical Trial Protocol;Letter;Multicenter Study
Daval, Mary;Corre, Alain;Palpacuer, Clement;Housset, Juliette;Poillon, Guillaume;Eliezer, Michael;Verillaud, Benjamin;Slama, Dorsaf;Ayache, Denis;Herman, Philippe;Jourdaine, Clement;Herve, Camille;El Bakkouri, Wissame;Salmon, Dominique;Hautefort, Charlotte
10.1186/s13063-020-04585-8
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Efficacy of local budesonide therapy in the management of persistent hyposmia in COVID-19 patients without signs of severity: A structured summary of a study protocol for a randomised controlled trial. [Abstract]: OBJECTIVES: To assess the efficacy of local intranasal treatment with budesonide (nasal irrigatio...
33,068,865
Int Immunopharmacol
Recent findings on the Coronavirus disease 2019 (COVID-19); immunopathogenesis and immunotherapeutics.
Severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) is responsible for recent ongoing public health emergency in the world. Sharing structural and behavioral similarities with its ancestors [SARS and Middle East Respiratory Syndrome (MERS)], SARS-CoV-2 has lower fatality but faster transmission. We have gone t...
coronavirus disease-2019;immune system;immunotherapeutics;severe acute respiratory syndrome coronavirus-2;treatment
Journal Article;Review
Ebrahimi, Negin;Aslani, Saeed;Babaie, Farhad;Hemmatzadeh, Maryam;Hosseinzadeh, Ramin;Joneidi, Zeinab;Mehdizadeh Tourzani, Zahra;Pakravan, Nafiseh;Mohammadi, Hamed
10.1016/j.intimp.2020.107082
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Recent findings on the Coronavirus disease 2019 (COVID-19); immunopathogenesis and immunotherapeutics. [Abstract]: Severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) is responsible for recent ongoing public health emergency in the world. Sharing structural and behavioral similarities with its ancesto...
32,512,494
Med Hypotheses
Could nutritional and functional status serve as prognostic factors for COVID-19 in the elderly?
Geriatric patients seem to be the most vulnerable group in COVID-19. These patients are usually characterized by impaired mobilization and malnutrition. In addition, obesity has been correlated with increased mortality rates after COVID-19 infection, highlighting the role of nutrition in prognosis of COVID-19 as well. ...
covid-19;elderly;frailty;functional status;malnutrition
Journal Article
Lidoriki, Irene;Frountzas, Maximos;Schizas, Dimitrios
10.1016/j.mehy.2020.109946
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Could nutritional and functional status serve as prognostic factors for COVID-19 in the elderly? [Abstract]: Geriatric patients seem to be the most vulnerable group in COVID-19. These patients are usually characterized by impaired mobilization and malnutrition. In addition, obesity has been correlated with inc...
32,490,518
J Public Health (Oxf)
The substantial awareness role of web-based and social media platforms in developing countries during a pandemic scenario: the example of COVID-19.
BACKGROUND: During the outbreak of coronavirus COVID-19, social media platforms have shown effectiveness in information dissemination. Delivering evidence-based medical knowledge and trustworthy recommendations is a difficult mission for classical entities, especially in a war-torn country with a fragile health system....
Letter
Abdul-Baki, Mohammad-Nasan;Dhemesh, Yaseen;Alasadi, Lugien;Alsuliman, Tamim
10.1093/pubmed/fdaa075
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The substantial awareness role of web-based and social media platforms in developing countries during a pandemic scenario: the example of COVID-19. [Abstract]: BACKGROUND: During the outbreak of coronavirus COVID-19, social media platforms have shown effectiveness in information dissemination. Delivering evide...
32,377,468
Cureus
First Case of an Infant with COVID-19 in the Middle East.
The novel coronavirus (COVID-19) has been declared a worldwide pandemic. It was initially thought to spare children and adolescents as significantly smaller number of cases have been reported in the pediatric population in comparison to adults. Here, we report the case of a 16-month-old female infant from Lebanon who p...
children;coronavirus;covid-19;gastrointestinal symptoms;infants;lebanon;middle east;pandemic;pediatrics;sars-cov-2
Case Reports
Mansour, Amani;Atoui, Rola;Kanso, Kamal;Mohsen, Rami;Fares, Youssef;Fares, Jawad
10.7759/cureus.7520
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: First Case of an Infant with COVID-19 in the Middle East. [Abstract]: The novel coronavirus (COVID-19) has been declared a worldwide pandemic. It was initially thought to spare children and adolescents as significantly smaller number of cases have been reported in the pediatric population in comparison to adul...
32,844,113
Can J Respir Ther
Helmet CPAP revisited in COVID-19 pneumonia: A case series.
Introduction: Noninvasive positive pressure ventilation (NIPPV) plays an important role in the management of respiratory failure. However, since the emergence of the COVID-19 pandemic, utilization of traditional face mask NIPPV has been curtailed in part due to risk of aerosolization of respiratory particles and subseq...
bipap;covid19;cpap; bilevel positive airway pressure;nippv;niv helmet;sars-cov2;continuous positive airway pressure;non-invasive positive pressure ventilation
Case Reports
Rali, Aniket S;Howard, Christopher;Miller, Rachel;Morgan, Christopher K;Mejia, Dennis;Sabo, John;Herlihy, James P;Devarajan, Sunjay R
10.29390/cjrt-2020-019
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Helmet CPAP revisited in COVID-19 pneumonia: A case series. [Abstract]: Introduction: Noninvasive positive pressure ventilation (NIPPV) plays an important role in the management of respiratory failure. However, since the emergence of the COVID-19 pandemic, utilization of traditional face mask NIPPV has been cu...
32,669,955
Int J Med Sci
A comprehensive investigation of the mRNA and protein level of ACE2, the putative receptor of SARS-CoV-2, in human tissues and blood cells.
The outbreak of pneumonia caused by SARS-CoV-2 posed a great threat to global human health, which urgently requires us to understand comprehensively the mechanism of SARS-CoV-2 infection. Angiotensin-converting enzyme 2 (ACE2) was identified as a functional receptor for SARS-CoV-2, distribution of which may indicate th...
angiotensin-converting enzyme 2;blood cells;human tissues;sars-cov-2
Journal Article
Wang, Yiliang;Wang, Yun;Luo, Weisheng;Huang, Lianzhou;Xiao, Ji;Li, Feng;Qin, Shurong;Song, Xiaowei;Wu, Yanting;Zeng, Qiongzhen;Jin, Fujun;Wang, Yifei
10.7150/ijms.46695
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: A comprehensive investigation of the mRNA and protein level of ACE2, the putative receptor of SARS-CoV-2, in human tissues and blood cells. [Abstract]: The outbreak of pneumonia caused by SARS-CoV-2 posed a great threat to global human health, which urgently requires us to understand comprehensively the mechan...
32,713,412
Disaster Med Public Health Prep
Mexico and the COVID-19 Response.
Mexico has been one of the most affected countries in the world by the COVID-19 pandemic. The true impact of the pandemic has probably been underestimated, and President Lopez Obrador, as well as the Ministry of Health, has struggled to lead the country since the beginning. While cases and deaths continue to rise, stro...
covid-19;mexico;coronavirus;leadership;pandemics;public health response;sentinel surveillance
Letter
Ibarra-Nava, Ismael;Cardenas-de la Garza, Jesus A;Ruiz-Lozano, Raul E;Salazar-Montalvo, Raul G
10.1017/dmp.2020.260
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Mexico and the COVID-19 Response. [Abstract]: Mexico has been one of the most affected countries in the world by the COVID-19 pandemic. The true impact of the pandemic has probably been underestimated, and President Lopez Obrador, as well as the Ministry of Health, has struggled to lead the country since the b...
32,489,751
Cureus
Managing Acute Portal Hypertensive Gastropathy Bleed During the Time of COVID-19 Pandemic: Novelty or Necessity?
Acute bleeding from portal hypertensive gastropathy (PHG) is an extremely rare event in the natural history of cirrhosis. The treatment recommendations include portal pressure reduction strategies including pharmacotherapy with vasoactive agents and beta-blockers and interventional strategies such as transjugular intra...
banding;cirrhosis;coronavirus;covid;endoscopy;evl;gi bleeding;phg
Case Reports
Philips, Cyriac A;Kumbar, Sandeep;Ahamed, Rizwan;Augustine, Philip
10.7759/cureus.8333
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Managing Acute Portal Hypertensive Gastropathy Bleed During the Time of COVID-19 Pandemic: Novelty or Necessity? [Abstract]: Acute bleeding from portal hypertensive gastropathy (PHG) is an extremely rare event in the natural history of cirrhosis. The treatment recommendations include portal pressure reduction ...
32,429,038
Trop Med Infect Dis
Prognosis of COVID-19 in Patients with Liver and Kidney Diseases: An Early Systematic Review and Meta-Analysis.
The mortality and severity in COVID-19 is increased in patients with comorbidities. The aim of this study was to evaluate the severity and mortality in COVID-19 patients with underlying kidney and liver diseases. We retrieved data on the clinical features and primary composite end point of COVID-19 patients from Medlin...
covid-19;sars-cov-2;alcohol-related liver disease;chronic kidney disease;cirrhosis;hepatitis b and c;necrosis;nonalcoholic steatohepatitis
Journal Article;Review
Oyelade, Tope;Alqahtani, Jaber;Canciani, Gabriele
10.3390/tropicalmed5020080
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Prognosis of COVID-19 in Patients with Liver and Kidney Diseases: An Early Systematic Review and Meta-Analysis. [Abstract]: The mortality and severity in COVID-19 is increased in patients with comorbidities. The aim of this study was to evaluate the severity and mortality in COVID-19 patients with underlying k...
32,281,114
Pharmacotherapy
Delayed Initiation of Remdesivir in a COVID-19-Positive Patient.
We present a case of late initiation of remdesivir antiviral therapy in the successful treatment of a patient with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a mixed medical intensive care unit of a community teaching hospital. A previously healthy 40-year-old man was admitted to the hospital 3 day...
covid-19;sars-cov-2;coronavirus;pneumonia;remdesivir;viral pneumonia
Case Reports
Hillaker, Emily;Belfer, Julie J;Bondici, Anamaria;Murad, Hani;Dumkow, Lisa E
10.1002/phar.2403
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Delayed Initiation of Remdesivir in a COVID-19-Positive Patient. [Abstract]: We present a case of late initiation of remdesivir antiviral therapy in the successful treatment of a patient with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a mixed medical intensive care unit of a community teac...
32,917,722
J Biol Chem
Sphingosine prevents binding of SARS-CoV-2 spike to its cellular receptor ACE2.
Sphingosine has been shown to prevent and eliminate bacterial infections of the respiratory tract, but it is unknown whether sphingosine can be also employed to prevent viral infections. To test this hypothesis, we analyzed whether sphingosine regulates the infection of cultured and freshly isolated ex vivo human epith...
ace2;sars-cov-2;epithelium;human nasal epithelial cells;infection;infectious disease;nasal epithelial cells;receptor;sphingolipid;sphingosine;spike;virus entry
Journal Article;Research Support, Non-U.S. Gov't
Edwards, Michael J;Becker, Katrin Anne;Gripp, Barbara;Hoffmann, Markus;Keitsch, Simone;Wilker, Barbara;Soddemann, Matthias;Gulbins, Anne;Carpinteiro, Elisa;Patel, Sameer H;Wilson, Gregory C;Pohlmann, Stefan;Walter, Silke;Fassbender, Klaus;Ahmad, Syed A;Carpinteiro, Alexander;Gulbins, Erich
10.1074/jbc.RA120.015249
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Sphingosine prevents binding of SARS-CoV-2 spike to its cellular receptor ACE2. [Abstract]: Sphingosine has been shown to prevent and eliminate bacterial infections of the respiratory tract, but it is unknown whether sphingosine can be also employed to prevent viral infections. To test this hypothesis, we anal...
32,782,048
Disaster Med Public Health Prep
Public Health Lessons Learned From Biases in Coronavirus Mortality Overestimation.
In testimony before US Congress on March 11, 2020, members of the House Oversight and Reform Committee were informed that estimated mortality for the novel coronavirus was 10-times higher than for seasonal influenza. Additional evidence, however, suggests the validity of this estimation could benefit from vetting for b...
covid-19;case fatality rate;coronavirus mortality overestimation;infection fatality rate;sampling bias
Journal Article
Brown, Ronald B
10.1017/dmp.2020.298
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Public Health Lessons Learned From Biases in Coronavirus Mortality Overestimation. [Abstract]: In testimony before US Congress on March 11, 2020, members of the House Oversight and Reform Committee were informed that estimated mortality for the novel coronavirus was 10-times higher than for seasonal influenza....
33,049,807
Carbohydr Polym
A review on chitosan and its development as pulmonary particulate anti-infective and anti-cancer drug carriers.
Chitosan, as a biodegradable and biocompatible polymer, is characterized by anti-microbial and anti-cancer properties. It lately has received a widespread interest for use as the pulmonary particulate backbone materials of drug carrier for the treatment of infectious disease and cancer. The success of chitosan as pulmo...
cancer;chitosan;infection;nanoparticle;pulmonary drug delivery
Journal Article;Review
Rasul, Ruhisy Mohd;Tamilarasi Muniandy, M;Zakaria, Zabliza;Shah, Kifayatullah;Chee, Chin Fei;Dabbagh, Ali;Rahman, Noorsaadah Abd;Wong, Tin Wui
10.1016/j.carbpol.2020.116800
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: A review on chitosan and its development as pulmonary particulate anti-infective and anti-cancer drug carriers. [Abstract]: Chitosan, as a biodegradable and biocompatible polymer, is characterized by anti-microbial and anti-cancer properties. It lately has received a widespread interest for use as the pulmonar...
32,380,802
Monaldi Arch Chest Dis
Cardiovascular system and COVID-19: perspectives from a developing country.
A novel coronavirus, SARS-CoV-2, thought to have originated from bats causes COVID-19 infection which was first reported from Wuhan, China in December 2019. This virus has a high infectivity rate and has impacted a significant chunk of the population worldwide. The spectrum of disease ranges from mild to severe with re...
Journal Article;Review
Kunal, Shekhar;Gupta, Kashish;Sharma, Shashi Mohan;Pathak, Vijay;Mittal, Shruti;Tarke, Chandrakant
10.4081/monaldi.2020.1305
[ 0, 1, 1, 1, 0, 0, 0 ]
[Title]: Cardiovascular system and COVID-19: perspectives from a developing country. [Abstract]: A novel coronavirus, SARS-CoV-2, thought to have originated from bats causes COVID-19 infection which was first reported from Wuhan, China in December 2019. This virus has a high infectivity rate and has impacted a signific...
32,225,175
Nature
Structural basis of receptor recognition by SARS-CoV-2.
A novel severe acute respiratory syndrome (SARS)-like coronavirus (SARS-CoV-2) recently emerged and is rapidly spreading in humans, causing COVID-19(1,2). A key to tackling this pandemic is to understand the receptor recognition mechanism of the virus, which regulates its infectivity, pathogenesis and host range. SARS-...
Comparative Study;Journal Article;Research Support, N.I.H., Extramural;Research Support, U.S. Gov't, Non-P.H.S.
Shang, Jian;Ye, Gang;Shi, Ke;Wan, Yushun;Luo, Chuming;Aihara, Hideki;Geng, Qibin;Auerbach, Ashley;Li, Fang
10.1038/s41586-020-2179-y
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Structural basis of receptor recognition by SARS-CoV-2. [Abstract]: A novel severe acute respiratory syndrome (SARS)-like coronavirus (SARS-CoV-2) recently emerged and is rapidly spreading in humans, causing COVID-19(1,2). A key to tackling this pandemic is to understand the receptor recognition mechanism of t...
32,705,587
Aging Clin Exp Res
COVID-19 and associations with frailty and multimorbidity: a prospective analysis of UK Biobank participants.
BACKGROUND: Frailty and multimorbidity have been suggested as risk factors for severe COVID-19 disease. AIMS: We investigated, in the UK Biobank, whether frailty and multimorbidity were associated with risk of hospitalisation with COVID-19. METHODS: 502,640 participants aged 40-69 years at baseline (54-79 years at COVI...
covid-19;epidemiology;frailty;musculoskeletal;osteoporosis;uk biobank
Journal Article
Woolford, S J;D'Angelo, S;Curtis, E M;Parsons, C M;Ward, K A;Dennison, E M;Patel, H P;Cooper, C;Harvey, N C
10.1007/s40520-020-01653-6
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: COVID-19 and associations with frailty and multimorbidity: a prospective analysis of UK Biobank participants. [Abstract]: BACKGROUND: Frailty and multimorbidity have been suggested as risk factors for severe COVID-19 disease. AIMS: We investigated, in the UK Biobank, whether frailty and multimorbidity were ass...
32,896,424
Child Abuse Negl
Brazilian Child Protection Professionals' Resilient Behavior during the COVID-19 Pandemic.
BACKGROUND: The COVID-19 pandemic deeply affected child protection professionals. One potential area of concern is whether and how the pandemic has dampened these individuals' ability to engage in the resilient practices that are so vital to their wellbeing. OBJECTIVE: Within the unique and understudied context of a de...
covid-19;child maltreatment;child protection;psychological resilience
Journal Article
Priolo Filho, Sidnei R;Goldfarb, Deborah;Zibetti, Murilo R;Aznar-Blefari, Carlos
10.1016/j.chiabu.2020.104701
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Brazilian Child Protection Professionals' Resilient Behavior during the COVID-19 Pandemic. [Abstract]: BACKGROUND: The COVID-19 pandemic deeply affected child protection professionals. One potential area of concern is whether and how the pandemic has dampened these individuals' ability to engage in the resilie...