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32,674,071
Eur J Endocrinol
How important is obesity as a risk factor for respiratory failure, intensive care admission and death in hospitalised COVID-19 patients? Results from a single Italian centre.
Objective: Specific comorbidities and old age create a greater vulnerability to severe Coronavirus Disease 19 (COVID-19). While obesity seems to aggravate the course of disease, the actual impact of the BMI and the cutoff which increases illness severity are still under investigation. The aim of the study was to analyz...
Evaluation Study;Journal Article
Rottoli, Matteo;Bernante, Paolo;Belvedere, Angela;Balsamo, Francesca;Garelli, Silvia;Giannella, Maddalena;Cascavilla, Alessandra;Tedeschi, Sara;Ianniruberto, Stefano;Rosselli Del Turco, Elena;Tonetti, Tommaso;Ranieri, Vito Marco;Poggioli, Gilberto;Manzoli, Lamberto;Pagotto, Uberto;Viale, Pierluigi;Bartoletti, Michele
10.1530/EJE-20-0541
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: How important is obesity as a risk factor for respiratory failure, intensive care admission and death in hospitalised COVID-19 patients? Results from a single Italian centre. [Abstract]: Objective: Specific comorbidities and old age create a greater vulnerability to severe Coronavirus Disease 19 (COVID-19). Wh...
32,711,053
Ann Epidemiol
Risk for COVID-19 infection and death among Latinos in the United States: examining heterogeneity in transmission dynamics.
PURPOSE: The purpose of this study was to ascertain COVID-19 transmission dynamics among Latino communities nationally. METHODS: We compared predictors of COVID-19 cases and deaths between disproportionally Latino counties (>/=17.8% Latino population) and all other counties through May 11, 2020. Adjusted rate ratios (a...
covid-19;disparity;hispanic;latino;race
Comparative Study;Journal Article
Rodriguez-Diaz, Carlos E;Guilamo-Ramos, Vincent;Mena, Leandro;Hall, Eric;Honermann, Brian;Crowley, Jeffrey S;Baral, Stefan;Prado, Guillermo J;Marzan-Rodriguez, Melissa;Beyrer, Chris;Sullivan, Patrick S;Millett, Gregorio A
10.1016/j.annepidem.2020.07.007
[ 0, 0, 1, 0, 1, 0, 0 ]
[Title]: Risk for COVID-19 infection and death among Latinos in the United States: examining heterogeneity in transmission dynamics. [Abstract]: PURPOSE: The purpose of this study was to ascertain COVID-19 transmission dynamics among Latino communities nationally. METHODS: We compared predictors of COVID-19 cases and d...
32,495,141
J Gastrointest Surg
Development and Validation of a Clinical Risk Score for Intensive Care Resource Utilization After Colon Cancer Surgery: a Practical Guide to the Selection of Patients During COVID-19.
BACKGROUND: The purpose of this study was to develop and validate a prediction model and clinical risk score for Intensive Care Resource Utilization after colon cancer surgery. METHODS: Adult (>/= 18 years old) patients from the 2012 to 2018 ACS-NSQIP colectomy-targeted database who underwent elective colon cancer surg...
covid-19;colon cancer;intensive care unit;surgery
Journal Article;Validation Study
Garfinkle, Richard;Abou-Khalil, Maria;Salama, Ebram;Marinescu, Daniel;Pang, Allison;Morin, Nancy;Demyttenaere, Sebastian;Liberman, A Sender;Vasilevsky, Carol-Ann;Boutros, Marylise
10.1007/s11605-020-04665-9
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Development and Validation of a Clinical Risk Score for Intensive Care Resource Utilization After Colon Cancer Surgery: a Practical Guide to the Selection of Patients During COVID-19. [Abstract]: BACKGROUND: The purpose of this study was to develop and validate a prediction model and clinical risk score for In...
32,656,306
Virusdisease
COVID-19 diagnostic approaches: different roads to the same destination.
SARS-CoV2, a previously unknown strain of coronaviruses caused a severe respiratory disease called Coronavirus disease (COVID-19) which emerged from Wuhan city of China on 30 December 2019, and declared as Global health problem by World Health Organisation within a month. In less than two and half months (11 March, 202...
biosensor;covid-19;diagnostic method for covid-19;rt-pcr;sars-cov2
Journal Article;Review
Kumar, Ramesh;Nagpal, Suman;Kaushik, Samander;Mendiratta, Sanjay
10.1007/s13337-020-00599-7
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: COVID-19 diagnostic approaches: different roads to the same destination. [Abstract]: SARS-CoV2, a previously unknown strain of coronaviruses caused a severe respiratory disease called Coronavirus disease (COVID-19) which emerged from Wuhan city of China on 30 December 2019, and declared as Global health proble...
32,893,786
J Coll Physicians Surg Pak
Computed Tomography Evaluation of Airway Changes in Adult Patients with COVID-19 Pneumonia.
OBJECTIVE: To investigate airway abnormalities on chest CT in adult patients with COVID-19 pneumonia. STUDY DESIGN: Observational study. PLACE AND DURATION OF STUDY: Department of Radiology, Affiliated Hospital of Jining Medical University, Jining, Shandong, China, from January to April, 2020. METHODOLOGY: CT scan imag...
Journal Article;Observational Study
Sun, Zhanguo;Liu, Xiaolong;Wang, Jiehuan;Wang, Xiaoqiang;Liu, Wei;Chen, Yueqin
10.29271/jcpsp.2020.08.785
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Computed Tomography Evaluation of Airway Changes in Adult Patients with COVID-19 Pneumonia. [Abstract]: OBJECTIVE: To investigate airway abnormalities on chest CT in adult patients with COVID-19 pneumonia. STUDY DESIGN: Observational study. PLACE AND DURATION OF STUDY: Department of Radiology, Affiliated Hospi...
32,713,239
J Am Heart Assoc
Cardio-Oncology in the Era of the COVID-19 Pandemic and Beyond.
Coronavirus disease 2019 (COVID-19) has emerged as a global pandemic and public health crisis. Increasing waves of intermittent infectious outbreaks have dramatically influenced care among broad populations. Over the past 2 decades, there has been a rapid increase in cancer survival, with >400 000 new survivors each ye...
covid-19;cancer;cardiac imaging;cardio-oncology;targeted therapies
Journal Article;Research Support, N.I.H., Extramural;Review
Addison, Daniel;Campbell, Courtney M;Guha, Avirup;Ghosh, Arjun K;Dent, Susan F;Jneid, Hani
10.1161/JAHA.120.017787
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Cardio-Oncology in the Era of the COVID-19 Pandemic and Beyond. [Abstract]: Coronavirus disease 2019 (COVID-19) has emerged as a global pandemic and public health crisis. Increasing waves of intermittent infectious outbreaks have dramatically influenced care among broad populations. Over the past 2 decades, th...
32,860,140
World J Surg
Changes in Emergency General Surgery During Covid-19 in Scotland: A Prospective Cohort Study.
INTRODUCTION: Covid-19 has had a significant impact on all aspects of health care. We aimed to characterise the trends in emergency general surgery at a district general hospital in Scotland. METHODS: A prospective cohort study was performed from 23/03/20 to 07/05/20. All emergency general surgery patients were include...
Journal Article
Dick, Lachlan;Green, James;Brown, Jasmine;Kennedy, Ewan;Cassidy, Richard;Othman, Salasiah;Berlansky, Martin
10.1007/s00268-020-05760-3
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Changes in Emergency General Surgery During Covid-19 in Scotland: A Prospective Cohort Study. [Abstract]: INTRODUCTION: Covid-19 has had a significant impact on all aspects of health care. We aimed to characterise the trends in emergency general surgery at a district general hospital in Scotland. METHODS: A pr...
32,722,950
Hemoglobin
Impact of COVID-19 Infection on 24 Patients with Sickle Cell Disease. One Center Urban Experience, Detroit, MI, USA.
The city of Detroit has a large population of individuals with sickle cell disease, and hospitals in Detroit have seen some of the highest numbers of cases of coronavirus disease-19 (COVID-19) in 2020. The purpose of this study was to examine the pathophysiological characteristics of COVID-19 in patients with sickle ce...
coronavirus disease-19 (covid-19);acute respiratory distress syndrome (ards);severe acute respiratory syndrome coronavirus 2 (sars-cov-2);sickle cell disease;sickle cell trait
Journal Article
Balanchivadze, Nino;Kudirka, Adam A;Askar, Sally;Almadhoun, Khaled;Kuriakose, Philip;Fadel, Raef;Dabak, Vrushali
10.1080/03630269.2020.1797775
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Impact of COVID-19 Infection on 24 Patients with Sickle Cell Disease. One Center Urban Experience, Detroit, MI, USA. [Abstract]: The city of Detroit has a large population of individuals with sickle cell disease, and hospitals in Detroit have seen some of the highest numbers of cases of coronavirus disease-19 ...
33,026,586
Arch Osteoporos
The impact of lockdown during the COVID-19 pandemic on osteoporotic fragility fractures: an observational study.
We investigated whether osteoporotic fractures declined during lockdown, among adults aged 50 years and older. We showed that fewer outpatients attended the Fracture Clinic, for non-hip fractures, during lockdown; in contrast, no change in admissions for hip fractures was observed. This could be due to fewer outdoors f...
covid-19;fragility fracture;hip fracture;older adults;secondary healthcare utilisation
Journal Article;Observational Study
Ogliari, Giulia;Lunt, Eleanor;Ong, Terence;Marshall, Lindsey;Sahota, Opinder
10.1007/s11657-020-00825-1
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The impact of lockdown during the COVID-19 pandemic on osteoporotic fragility fractures: an observational study. [Abstract]: We investigated whether osteoporotic fractures declined during lockdown, among adults aged 50 years and older. We showed that fewer outpatients attended the Fracture Clinic, for non-hip ...
32,275,643
Aging (Albany NY)
Predictors for imaging progression on chest CT from coronavirus disease 2019 (COVID-19) patients.
OBJECTIVE: This study aimed to investigate the potential parameters associated with imaging progression on chest CT from coronavirus disease 19 (COVID-19) patients. RESULTS: The average age of 273 COVID-19 patients enrolled with imaging progression were older than those without imaging progression (p = 0.006). The whit...
covid-19;mlr;age;coronavirus disease 2019;monocyte-lymphocyte ratio
Journal Article;Research Support, Non-U.S. Gov't
Yang, Zongguo;Shi, Jia;He, Zhang;Lu, Ying;Xu, Qingnian;Ye, Chen;Chen, Shishi;Tang, Bozong;Yin, Keshan;Lu, Yunfei;Chen, Xiaorong
10.18632/aging.102999
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Predictors for imaging progression on chest CT from coronavirus disease 2019 (COVID-19) patients. [Abstract]: OBJECTIVE: This study aimed to investigate the potential parameters associated with imaging progression on chest CT from coronavirus disease 19 (COVID-19) patients. RESULTS: The average age of 273 COVI...
32,990,177
J Biol Dyn
Mathematical modelling on COVID-19 transmission impacts with preventive measures: a case study of Tanzania.
The outbreak of COVID-19 was first experienced in Wuhan City, China, during December 2019 before it rapidly spread over globally. This paper has proposed a mathematical model for studying its transmission dynamics in the presence of face mask wearing and hospitalization services of human population in Tanzania. Disease...
covid-19;basic reproduction number;equilibrium points and stability
Journal Article
Mumbu, Abdul-Rahman J;Hugo, Alfred K
10.1080/17513758.2020.1823494
[ 0, 0, 1, 0, 1, 0, 0 ]
[Title]: Mathematical modelling on COVID-19 transmission impacts with preventive measures: a case study of Tanzania. [Abstract]: The outbreak of COVID-19 was first experienced in Wuhan City, China, during December 2019 before it rapidly spread over globally. This paper has proposed a mathematical model for studying its...
32,398,162
Hum Genomics
COVID-19 vulnerability: the potential impact of genetic susceptibility and airborne transmission.
The recent coronavirus disease (COVID-19), caused by SARS-CoV-2, is inarguably the most challenging coronavirus outbreak relative to the previous outbreaks involving SARS-CoV and MERS-CoV. With the number of COVID-19 cases now exceeding 2 million worldwide, it is apparent that (i) transmission of SARS-CoV-2 is very hig...
Journal Article;Review
Godri Pollitt, Krystal J;Peccia, Jordan;Ko, Albert I;Kaminski, Naftali;Dela Cruz, Charles S;Nebert, Daniel W;Reichardt, Juergen K V;Thompson, David C;Vasiliou, Vasilis
10.1186/s40246-020-00267-3
[ 0, 0, 1, 1, 1, 0, 0 ]
[Title]: COVID-19 vulnerability: the potential impact of genetic susceptibility and airborne transmission. [Abstract]: The recent coronavirus disease (COVID-19), caused by SARS-CoV-2, is inarguably the most challenging coronavirus outbreak relative to the previous outbreaks involving SARS-CoV and MERS-CoV. With the num...
32,621,438
Zhongguo Yi Liao Qi Xie Za Zhi
[Discussion of Medical Protective Consumables Management to Fight against COVID-19 Pneumonia].
This article researches how to allocate medical protective consumables in hospital and ensure the safety of emergency marketing procurement under the condition that people are easily susceptible to COVID-19. To inform medical staffs about the standard instruction, we establish the corresponding hierarchical control man...
covid-19 pneumonia;management;medical protective consumables
Journal Article
Yu, Jing;Zhu, Jianghua;Huang, Liang;Lyu, Zhongwei
10.3969/j.issn.1671-7104.2020.03.016
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [Discussion of Medical Protective Consumables Management to Fight against COVID-19 Pneumonia]. [Abstract]: This article researches how to allocate medical protective consumables in hospital and ensure the safety of emergency marketing procurement under the condition that people are easily susceptible to COVID-...
32,346,873
J Med Virol
Epidemiological and clinical features of asymptomatic patients with SARS-CoV-2 infection.
Few studies reported the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected patients with completely asymptomatic throughout the disease course. We investigated the epidemiological and clinical features of patients infected by SARS-CoV-2 without any symptoms. Patients with confirmed SARS-CoV-2 infect...
asymptomatic;coronavirus disease 2019;severe acute respiratory syndrome coronavirus 2
Journal Article;Research Support, Non-U.S. Gov't
Xu, Tianmin;Huang, Rui;Zhu, Li;Wang, Jian;Cheng, Juan;Zhang, Biao;Zhao, Haiyan;Chen, Kang;Shao, Huaping;Zhu, Chuanwu;Wu, Chao;Liu, Longgen
10.1002/jmv.25944
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Epidemiological and clinical features of asymptomatic patients with SARS-CoV-2 infection. [Abstract]: Few studies reported the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected patients with completely asymptomatic throughout the disease course. We investigated the epidemiological and clini...
32,785,209
Pol Arch Intern Med
Molecular epidemiology of SARS CoV-2: a review of current data on genetic variability of the virus.
Severe acute respiratory syndrome coronavirus 2 (SARS CoV-2), associated with coronavirus disease (COVID-19) is a novel pathogen recently introduced to the human population. It may be characterised by the rapid epidemic transmissions due to lack of the herd immunity and notable mortality, increasing with age and among ...
Journal Article;Review
Parczewski, Milosz;Ciechanowicz, Andrzej
10.20452/pamw.15550
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Molecular epidemiology of SARS CoV-2: a review of current data on genetic variability of the virus. [Abstract]: Severe acute respiratory syndrome coronavirus 2 (SARS CoV-2), associated with coronavirus disease (COVID-19) is a novel pathogen recently introduced to the human population. It may be characterised b...
32,191,764
PLoS One
Association of radiologic findings with mortality of patients infected with 2019 novel coronavirus in Wuhan, China.
Radiologic characteristics of 2019 novel coronavirus (2019-nCoV) infected pneumonia (NCIP) which had not been fully understood are especially important for diagnosing and predicting prognosis. We retrospective studied 27 consecutive patients who were confirmed NCIP, the clinical characteristics and CT image findings we...
Journal Article
Yuan, Mingli;Yin, Wen;Tao, Zhaowu;Tan, Weijun;Hu, Yi
10.1371/journal.pone.0230548
[ 0, 1, 0, 1, 0, 0, 0 ]
[Title]: Association of radiologic findings with mortality of patients infected with 2019 novel coronavirus in Wuhan, China. [Abstract]: Radiologic characteristics of 2019 novel coronavirus (2019-nCoV) infected pneumonia (NCIP) which had not been fully understood are especially important for diagnosing and predicting p...
33,019,676
Healthcare (Basel)
Feasibility Trial of an eHealth Intervention for Health-Related Quality of Life: Implications for Managing Patients with Chronic Pain during the COVID-19 Pandemic.
PURPOSE: This study was conducted to determine the feasibility of providing an eHealth intervention for health-related quality of life (HRQOL) to facilitate patient self-management. METHODS: A randomized controlled trial was conducted from 2019-2020 within the Pain Registry for Epidemiological, Clinical, and Interventi...
covid-19;back-related disability;chronic low back pain;ehealth;health-related quality of life;low back pain intensity;randomized controlled trial
Journal Article
Licciardone, John C;Pandya, Vishruti
10.3390/healthcare8040381
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Feasibility Trial of an eHealth Intervention for Health-Related Quality of Life: Implications for Managing Patients with Chronic Pain during the COVID-19 Pandemic. [Abstract]: PURPOSE: This study was conducted to determine the feasibility of providing an eHealth intervention for health-related quality of life ...
32,767,259
Curr Med Sci
Deficiency of Tfh Cells and Germinal Center in Deceased COVID-19 Patients.
The COVID-19 pandemic caused by SARS-CoV2 is characterized by a remarkable variation in clinical severity ranging from a mild illness to a fatal multi-organ disease. Understanding the dysregulated human immune responses in the fatal subjects is critical for management of COVID-19 patients and the pandemic. In this stud...
covid-19;t follicular helper cells;germinal center;immune responses
Case Reports;Journal Article
Duan, Ya-Qi;Xia, Ming-Hui;Ren, Liang;Zhang, Yan-Fang;Ao, Qi-Lin;Xu, San-Peng;Kuang, Dong;Liu, Qian;Yan, Bing;Zhou, Yi-Wu;Chu, Qian;Liu, Liang;Yang, Xiang-Ping;Wang, Guo-Ping
10.1007/s11596-020-2225-x
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Deficiency of Tfh Cells and Germinal Center in Deceased COVID-19 Patients. [Abstract]: The COVID-19 pandemic caused by SARS-CoV2 is characterized by a remarkable variation in clinical severity ranging from a mild illness to a fatal multi-organ disease. Understanding the dysregulated human immune responses in t...
32,617,690
Eur Radiol
A deep learning approach to characterize 2019 coronavirus disease (COVID-19) pneumonia in chest CT images.
OBJECTIVES: To utilize a deep learning model for automatic detection of abnormalities in chest CT images from COVID-19 patients and compare its quantitative determination performance with radiological residents. METHODS: A deep learning algorithm consisted of lesion detection, segmentation, and location was trained and...
covid-19;deep learning;diagnosis;multidetector computed tomography;pneumonia
Comparative Study;Journal Article;Multicenter Study
Ni, Qianqian;Sun, Zhi Yuan;Qi, Li;Chen, Wen;Yang, Yi;Wang, Li;Zhang, Xinyuan;Yang, Liu;Fang, Yi;Xing, Zijian;Zhou, Zhen;Yu, Yizhou;Lu, Guang Ming;Zhang, Long Jiang
10.1007/s00330-020-07044-9
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: A deep learning approach to characterize 2019 coronavirus disease (COVID-19) pneumonia in chest CT images. [Abstract]: OBJECTIVES: To utilize a deep learning model for automatic detection of abnormalities in chest CT images from COVID-19 patients and compare its quantitative determination performance with radi...
32,438,446
Clin Pharmacol Ther
Prioritization of Anti-SARS-Cov-2 Drug Repurposing Opportunities Based on Plasma and Target Site Concentrations Derived from their Established Human Pharmacokinetics.
There is a rapidly expanding literature on the in vitro antiviral activity of drugs that may be repurposed for therapy or chemoprophylaxis against severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2). However, this has not been accompanied by a comprehensive evaluation of the target plasma and lung concentratio...
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't;Review
Arshad, Usman;Pertinez, Henry;Box, Helen;Tatham, Lee;Rajoli, Rajith K R;Curley, Paul;Neary, Megan;Sharp, Joanne;Liptrott, Neill J;Valentijn, Anthony;David, Christopher;Rannard, Steve P;O'Neill, Paul M;Aljayyoussi, Ghaith;Pennington, Shaun H;Ward, Stephen A;Hill, Andrew;Back, David J;Khoo, Saye H;Bray, Patrick G;Biagini...
10.1002/cpt.1909
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Prioritization of Anti-SARS-Cov-2 Drug Repurposing Opportunities Based on Plasma and Target Site Concentrations Derived from their Established Human Pharmacokinetics. [Abstract]: There is a rapidly expanding literature on the in vitro antiviral activity of drugs that may be repurposed for therapy or chemoproph...
32,907,672
Disaster Med Public Health Prep
Performing Qualitative Mask Fit Testing Without a Commercial Kit: Fit Testing Which Can Be Performed at Home and at Work.
OBJECTIVE: Qualitative fit testing is a popular method of ensuring the fit of sealing face masks such as N95 and FFP3 masks. Increased demand due to the coronavirus disease 2019 (COVID-19) pandemic has led to shortages in testing equipment and has forced many institutions to abandon fit testing. Three key materials are...
behavioral risk factor surveillance;health communication;quality of health care;risk assessment;safety management
Journal Article
O'Kelly, Eugenia;Arora, Anmol;Pearson, Charlotte;Ward, James R;Clarkson, P John
10.1017/dmp.2020.352
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Performing Qualitative Mask Fit Testing Without a Commercial Kit: Fit Testing Which Can Be Performed at Home and at Work. [Abstract]: OBJECTIVE: Qualitative fit testing is a popular method of ensuring the fit of sealing face masks such as N95 and FFP3 masks. Increased demand due to the coronavirus disease 2019...
32,573,469
Clin Chem Lab Med
SARS-CoV-2 RNA identification in nasopharyngeal swabs: issues in pre-analytics.
Objectives: The direct identification of SARS-CoV-2 RNA in nasopharyngeal swabs is recommended for diagnosing the novel COVID-19 disease. Pre-analytical determinants, such as sampling procedures, time and temperature storage conditions, might impact on the end result. Our aim was to evaluate the effects of sampling pro...
covid-19;sars-cov-2;nasopharyngeal swab;pre-analytical
Journal Article
Basso, Daniela;Aita, Ada;Navaglia, Filippo;Franchin, Elisa;Fioretto, Paola;Moz, Stefania;Bozzato, Dania;Zambon, Carlo-Federico;Martin, Barbara;Dal Pra, Chiara;Crisanti, Andrea;Plebani, Mario
10.1515/cclm-2020-0749
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: SARS-CoV-2 RNA identification in nasopharyngeal swabs: issues in pre-analytics. [Abstract]: Objectives: The direct identification of SARS-CoV-2 RNA in nasopharyngeal swabs is recommended for diagnosing the novel COVID-19 disease. Pre-analytical determinants, such as sampling procedures, time and temperature st...
32,977,764
BMC Infect Dis
Different clinical presentations of two renal transplant recipients with coronavirus disease 2019: a case report.
BACKGROUND: The Coronavirus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome Coronavirus-2 has spread rapidly worldwide and disease spread is currently increasing. Data on the clinical picture of transplant recipients and management of the anti-rejection immunosuppressive therapy on COVID-19 infectio...
acute respiratory syndrome coronavirus 2;case report;coronavirus disease 2019;immunosuppressive therapy;renal transplant recipients
Case Reports;Journal Article
Li, Jing;Chen, Gang;Zhang, Mingmin;Tu, Shenghao;Chen, Chao
10.1186/s12879-020-05434-4
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Different clinical presentations of two renal transplant recipients with coronavirus disease 2019: a case report. [Abstract]: BACKGROUND: The Coronavirus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome Coronavirus-2 has spread rapidly worldwide and disease spread is currently increasing. Da...
32,291,197
Diagn Interv Imaging
COVID-19 pneumonia: A review of typical CT findings and differential diagnosis.
The standard of reference for confirming COVID-19 relies on microbiological tests such as real-time polymerase chain reaction (RT-PCR) or sequencing. However, these tests might not be available in an emergency setting. Computed tomography (CT) can be used as an important complement for the diagnosis of COVID-19 pneumon...
covid-19 pneumonia;cryptogenic organizing pneumonia;pneumonia;tomography;x-ray computed
Journal Article;Review
Hani, C;Trieu, N H;Saab, I;Dangeard, S;Bennani, S;Chassagnon, G;Revel, M-P
10.1016/j.diii.2020.03.014
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: COVID-19 pneumonia: A review of typical CT findings and differential diagnosis. [Abstract]: The standard of reference for confirming COVID-19 relies on microbiological tests such as real-time polymerase chain reaction (RT-PCR) or sequencing. However, these tests might not be available in an emergency setting. ...
32,964,067
Open Forum Infect Dis
Assessment of Oropharyngeal Specimens for Discontinuation of Transmission-Based COVID-19 Precautions.
We compared oropharyngeal swab test performance with nasopharyngeal testing for discontinuation of transmission-based COVID-19 precautions. We performed a retrospective review of confirmed COVID-19-positive patients who received paired nasopharyngeal and oropharyngeal SARS-CoV-2 tests for clearance from isolation from ...
covid-19;coronavirus pcr;discharge strategies;oropharyngeal swabs;residential substance use treatment;transmission-based precautions
Journal Article
Barocas, Joshua A;Komaromy, Miriam;Haidar, Deeanna;Barlam, Tamar F;Orr, Beverley L;Miller, Nancy S
10.1093/ofid/ofaa382
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Assessment of Oropharyngeal Specimens for Discontinuation of Transmission-Based COVID-19 Precautions. [Abstract]: We compared oropharyngeal swab test performance with nasopharyngeal testing for discontinuation of transmission-based COVID-19 precautions. We performed a retrospective review of confirmed COVID-19...
32,251,618
J Pharm Pharm Sci
Current Drugs with Potential for Treatment of COVID-19: A Literature Review.
PURPOSE: SARS-CoV-2 first emerged in China in December 2019 and rapidly spread worldwide. No vaccine or approved drug is available to eradicate the virus, however, some drugs that are indicated for other afflictions seems to be potentially beneficial to treat the infection albeit without unequivocal evidence. The aim o...
Journal Article;Review
Md Insiat Islam Rabby
10.18433/jpps31002
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Current Drugs with Potential for Treatment of COVID-19: A Literature Review. [Abstract]: PURPOSE: SARS-CoV-2 first emerged in China in December 2019 and rapidly spread worldwide. No vaccine or approved drug is available to eradicate the virus, however, some drugs that are indicated for other afflictions seems ...
32,836,840
Environ Resour Econ (Dordr)
A Study on Herd Immunity of COVID-19 in South Korea: Using a Stochastic Economic-Epidemiological Model.
Vaccination is an effective measure to control the diffusion of infectious disease such as COVID-19. This paper analyzes the basic reproduction number in South Korea which enables us to identify a necessary level of vaccine stockpile to achieve herd immunity. An susceptible-infected-susceptible model is adopted that al...
covid-19;sis;stochastic disease;vaccination stockpile
Journal Article
Park, Hojeong;Kim, Songhee H
10.1007/s10640-020-00439-8
[ 0, 0, 0, 0, 0, 1, 0 ]
[Title]: A Study on Herd Immunity of COVID-19 in South Korea: Using a Stochastic Economic-Epidemiological Model. [Abstract]: Vaccination is an effective measure to control the diffusion of infectious disease such as COVID-19. This paper analyzes the basic reproduction number in South Korea which enables us to identify ...
32,362,697
Physica D
Accurate closed-form solution of the SIR epidemic model.
An accurate closed-form solution is obtained to the SIR Epidemic Model through the use of Asymptotic Approximants (Barlow et al., 2017). The solution is created by analytically continuing the divergent power series solution such that it matches the long-time asymptotic behavior of the epidemic model. The utility of the...
analytic solution;approximant;asymptotic analysis;sir model
Journal Article
Barlow, Nathaniel S;Weinstein, Steven J
10.1016/j.physd.2020.132540
[ 0, 0, 0, 0, 0, 1, 0 ]
[Title]: Accurate closed-form solution of the SIR epidemic model. [Abstract]: An accurate closed-form solution is obtained to the SIR Epidemic Model through the use of Asymptotic Approximants (Barlow et al., 2017). The solution is created by analytically continuing the divergent power series solution such that it match...
32,729,810
Radiology
Automated Assessment of COVID-19 Reporting and Data System and Chest CT Severity Scores in Patients Suspected of Having COVID-19 Using Artificial Intelligence.
Background The coronavirus disease 2019 (COVID-19) pandemic has spread across the globe with alarming speed, morbidity, and mortality. Immediate triage of patients with chest infections suspected to be caused by COVID-19 using chest CT may be of assistance when results from definitive viral testing are delayed. Purpose...
Journal Article;Multicenter Study
Lessmann, Nikolas;Sanchez, Clara I;Beenen, Ludo;Boulogne, Luuk H;Brink, Monique;Calli, Erdi;Charbonnier, Jean-Paul;Dofferhoff, Ton;van Everdingen, Wouter M;Gerke, Paul K;Geurts, Bram;Gietema, Hester A;Groeneveld, Miriam;van Harten, Louis;Hendrix, Nils;Hendrix, Ward;Huisman, Henkjan J;Isgum, Ivana;Jacobs, Colin;Kluge, R...
10.1148/radiol.2020202439
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Automated Assessment of COVID-19 Reporting and Data System and Chest CT Severity Scores in Patients Suspected of Having COVID-19 Using Artificial Intelligence. [Abstract]: Background The coronavirus disease 2019 (COVID-19) pandemic has spread across the globe with alarming speed, morbidity, and mortality. Imme...
32,893,160
Respir Investig
Outcome of early-stage combination treatment with favipiravir and methylprednisolone for severe COVID-19 pneumonia: A report of 11 cases.
Although the use of corticosteroids is not recommended in the World Health Organization statement for the treatment of coronavirus disease 2019 (COVID-19), steroid therapy may be indicated for critical cases in specific situations. Here, we report the successful treatment of 11 cases of severe COVID-19 pneumonia with f...
favipiravir;methylprednisolone;novel coronavirus disease 2019;severe illness
Journal Article
Murohashi, Kota;Hagiwara, Eri;Kitayama, Takaaki;Yamaya, Takafumi;Higa, Katsuyuki;Sato, Yozo;Otoshi, Ryota;Shintani, Ryota;Okabayashi, Hiroko;Ikeda, Satoshi;Niwa, Takashi;Nakazawa, Atsuhito;Oda, Tsuneyuki;Okuda, Ryo;Sekine, Akimasa;Kitamura, Hideya;Baba, Tomohisa;Komatsu, Shigeru;Iwasawa, Tae;Kaneko, Takeshi;Ogura, Taka...
10.1016/j.resinv.2020.08.001
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Outcome of early-stage combination treatment with favipiravir and methylprednisolone for severe COVID-19 pneumonia: A report of 11 cases. [Abstract]: Although the use of corticosteroids is not recommended in the World Health Organization statement for the treatment of coronavirus disease 2019 (COVID-19), stero...
32,576,982
Nat Hum Behav
COVID-19 Government Response Event Dataset (CoronaNet v.1.0).
Governments worldwide have implemented countless policies in response to the COVID-19 pandemic. We present an initial public release of a large hand-coded dataset of over 13,000 such policy announcements across more than 195 countries. The dataset is updated daily, with a 5-day lag for validity checking. We document po...
Journal Article
Cheng, Cindy;Barcelo, Joan;Hartnett, Allison Spencer;Kubinec, Robert;Messerschmidt, Luca
10.1038/s41562-020-0909-7
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 Government Response Event Dataset (CoronaNet v.1.0). [Abstract]: Governments worldwide have implemented countless policies in response to the COVID-19 pandemic. We present an initial public release of a large hand-coded dataset of over 13,000 such policy announcements across more than 195 countries. T...
32,596,874
J Paediatr Child Health
Filling in the gaps.
The COVID-19 pandemic, and our response to it, has created many voids in our lives, with no-one spared of its effects. As a result, we have all looked for, and found ways to fill in the gaps. In the midst of the epidemic, with healthcare providers in New York City pushed to the extremes of what can be asked of them, th...
Journal Article;Personal Narrative
Khatami, Ameneh
10.1111/jpc.15026
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Filling in the gaps. [Abstract]: The COVID-19 pandemic, and our response to it, has created many voids in our lives, with no-one spared of its effects. As a result, we have all looked for, and found ways to fill in the gaps. In the midst of the epidemic, with healthcare providers in New York City pushed to the...
32,768,300
J Thorac Cardiovasc Surg
Cardiac surgery in North America and coronavirus disease 2019 (COVID-19): Regional variability in burden and impact.
OBJECTIVE: The coronavirus disease 2019 (COVID-19) pandemic has resulted in an increase in hospital resource utilization and the need to defer nonurgent cardiac surgery procedures. The present study aims to report the regional variations of North American adult cardiac surgical case volume and case mix through the firs...
covid-19;cardiac surgery;cardiovascular surgery;case volume;coronavirus disease 2019
Journal Article
Ad, Niv;Luc, Jessica G Y;Nguyen, Tom C
10.1016/j.jtcvs.2020.06.077
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Cardiac surgery in North America and coronavirus disease 2019 (COVID-19): Regional variability in burden and impact. [Abstract]: OBJECTIVE: The coronavirus disease 2019 (COVID-19) pandemic has resulted in an increase in hospital resource utilization and the need to defer nonurgent cardiac surgery procedures. T...
32,674,825
J Am Med Dir Assoc
Reducing Social Isolation of Seniors during COVID-19 through Medical Student Telephone Contact.
Social isolation has been associated with many adverse health outcomes in older adults. We describe a phone call outreach program in which health care professional student volunteers phoned older adults, living in long-term care facilities and the community, at risk of social isolation during the COVID-19 pandemic. Con...
covid-19;medical education;social isolation;telehealth
Journal Article
Office, Emma E;Rodenstein, Marissa S;Merchant, Tazim S;Pendergrast, Tricia Rae;Lindquist, Lee A
10.1016/j.jamda.2020.06.003
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Reducing Social Isolation of Seniors during COVID-19 through Medical Student Telephone Contact. [Abstract]: Social isolation has been associated with many adverse health outcomes in older adults. We describe a phone call outreach program in which health care professional student volunteers phoned older adults,...
32,781,078
Urology
Outreach and Influence of Surgical Societies' Recommendations on Minimally Invasive Surgery During the COVID-19 Pandemic-An Anonymized International Urologic Expert Inquiry.
OBJECTIVE: To assess the outreach and influence of the main recommendations of surgical governing bodies on adaptation of minimally invasive laparoscopic surgery (MIS) procedures during the coronavirus disease 2019 (COVID-19) pandemic in an anonymized multi-institutional survey. MATERIALS AND METHODS: International exp...
Journal Article;Multicenter Study
Boehm, Katharina;Thomas, Anita;Bex, Axel;Black, Peter C;Coburn, Michael;Haferkamp, Axel;Hamdy, Freddie;Kaufman, Ronald P Jr;Klotz, Laurence;Lerner, Seth P;Pushkar, Dmitry;Ramon, Jacob;Rosenzweig, Barak;Tsaur, Igor
10.1016/j.urology.2020.07.043
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Outreach and Influence of Surgical Societies' Recommendations on Minimally Invasive Surgery During the COVID-19 Pandemic-An Anonymized International Urologic Expert Inquiry. [Abstract]: OBJECTIVE: To assess the outreach and influence of the main recommendations of surgical governing bodies on adaptation of min...
32,946,412
J Med Internet Res
Topics, Delivery Modes, and Social-Epistemological Dimensions of Web-Based Information for Patients Undergoing Renal Transplant and Living Donors During the COVID-19 Pandemic: Content Analysis.
BACKGROUND: The COVID-19 pandemic has markedly affected renal transplant care. During this time of social distancing, limited in-person visits, and uncertainty, patients and donors are relying more than ever on telemedicine and web-based information. Several factors can influence patients' understanding of web-based in...
covid-19;constructivism;ehealth;health communication;internet;patient education;renal transplantation;social-epistemological dimensions;teaching modes;web-based information;websites
Journal Article
van Klaveren, Charlotte W;de Jong, Peter G M;Hendriks, Renee A;Luk, Franka;de Vries, Aiko P J;van der Boog, Paul J M;Reinders, Marlies E J
10.2196/22068
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Topics, Delivery Modes, and Social-Epistemological Dimensions of Web-Based Information for Patients Undergoing Renal Transplant and Living Donors During the COVID-19 Pandemic: Content Analysis. [Abstract]: BACKGROUND: The COVID-19 pandemic has markedly affected renal transplant care. During this time of social...
32,649,399
Pediatr Crit Care Med
The Impact of Coronavirus Disease 2019 Pandemic on U.S. and Canadian PICUs.
OBJECTIVES: There are limited reports of the impact of the coronavirus disease 2019 pandemic focused on U.S. and Canadian PICUs. This hypothesis-generating report aims to identify the United States and Canadian trends of coronavirus disease 2019 in PICUs. DESIGN AND SETTING: To better understand how the coronavirus dis...
Journal Article
Sachdeva, Ramesh;Rice, Tom B;Reisner, Brian;Brundage, Nancy;Hulbert, Cheryl;Kaminski, Alex;Wetzel, Randall C
10.1097/PCC.0000000000002510
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The Impact of Coronavirus Disease 2019 Pandemic on U.S. and Canadian PICUs. [Abstract]: OBJECTIVES: There are limited reports of the impact of the coronavirus disease 2019 pandemic focused on U.S. and Canadian PICUs. This hypothesis-generating report aims to identify the United States and Canadian trends of co...
32,775,207
IDCases
Meningoencephalitis from SARS-CoV-2 infection.
The current global pandemic of COVID-19 disease is caused by a novel coronavirus SARS-CoV-2. This typically causes severe respiratory illness, however, as cases have multiplied across the globe, protean manifestations involving multiple organ systems have been described. We report a case of a 35-year-old woman with men...
covid-19;csf;coronavirus;meningoencephalitis;nervous system;sars-cov-2
Case Reports
Hafizi, Fatima;Kherani, Saleema;Shams, Madeeha
10.1016/j.idcr.2020.e00919
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Meningoencephalitis from SARS-CoV-2 infection. [Abstract]: The current global pandemic of COVID-19 disease is caused by a novel coronavirus SARS-CoV-2. This typically causes severe respiratory illness, however, as cases have multiplied across the globe, protean manifestations involving multiple organ systems h...
32,863,810
J Electroanal Chem (Lausanne)
Recent advances and challenges in electrochemical biosensors for emerging and re-emerging infectious diseases.
The rise of emerging infectious diseases (EIDs) as well as the increase in spread of existing infections is threatening global economies and human lives, with several countries still fighting repeated onslaught of a few of these epidemics. The catastrophic impact a pandemic has on humans and economy should serve as a r...
amperometry;covid-19;corona virus;impedance;potentiometry;voltammetry
Journal Article;Review
Menon, Shalini;Mathew, Manna Rachel;Sam, Sonia;Keerthi, K;Kumar, K Girish
10.1016/j.jelechem.2020.114596
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Recent advances and challenges in electrochemical biosensors for emerging and re-emerging infectious diseases. [Abstract]: The rise of emerging infectious diseases (EIDs) as well as the increase in spread of existing infections is threatening global economies and human lives, with several countries still fight...
32,704,477
Case Rep Womens Health
Fetal deaths in pregnancies with SARS-CoV-2 infection in Brazil: A case series.
Background: There are few reports of miscarriages or stillbirths in women infected with SARS-CoV-2. We present five consecutive cases of fetal death (>/=12 weeks) without other putative causes in women with laboratory-confirmed (RT-PCR) COVID-19 managed in a single Brazilian institution. Case series: All five women wer...
af, amniotic fluid;abortion;bmi, body mass index;bp, blood pressure;covid-19;cs, cesarean section;ed, emergency department;fhr, fetal heart rate;fetal death;ga, gestational age;hr, heart rate;infectious disease transmission;rr, respiratory rate;spo2, oxygen saturation;spontaneous;stillbirth;us, ultrasound;vertical;z-st...
Case Reports
Richtmann, Rosana;Torloni, Maria Regina;Oyamada Otani, Andre Ricardo;Levi, Jose Eduardo;Crema Tobara, Mariana;de Almeida Silva, Camila;Dias, Livio;Miglioli-Galvao, Lisia;Martins Silva, Pollyanna;Macoto Kondo, Mario
10.1016/j.crwh.2020.e00243
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Fetal deaths in pregnancies with SARS-CoV-2 infection in Brazil: A case series. [Abstract]: Background: There are few reports of miscarriages or stillbirths in women infected with SARS-CoV-2. We present five consecutive cases of fetal death (>/=12 weeks) without other putative causes in women with laboratory-c...
32,797,054
PLoS One
Impact of cardiovascular risk profile on COVID-19 outcome. A meta-analysis.
BACKGROUND: The ongoing pandemic of Novel Coronavirus Disease 2019 (COVID-19) infection has created a global emergency. Despite the infection causes a mild illness to most people, some patients are severely affected, demanding an urgent need to better understand how to risk-stratify infected subjects. DESIGN: This is a...
Journal Article;Meta-Analysis
Sabatino, Jolanda;De Rosa, Salvatore;Di Salvo, Giovanni;Indolfi, Ciro
10.1371/journal.pone.0237131
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Impact of cardiovascular risk profile on COVID-19 outcome. A meta-analysis. [Abstract]: BACKGROUND: The ongoing pandemic of Novel Coronavirus Disease 2019 (COVID-19) infection has created a global emergency. Despite the infection causes a mild illness to most people, some patients are severely affected, demand...
32,948,856
Nat Biotechnol
Measurement of SARS-CoV-2 RNA in wastewater tracks community infection dynamics.
We measured severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA concentrations in primary sewage sludge in the New Haven, Connecticut, USA, metropolitan area during the Coronavirus Disease 2019 (COVID-19) outbreak in Spring 2020. SARS-CoV-2 RNA was detected throughout the more than 10-week study and, when ...
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Peccia, Jordan;Zulli, Alessandro;Brackney, Doug E;Grubaugh, Nathan D;Kaplan, Edward H;Casanovas-Massana, Arnau;Ko, Albert I;Malik, Amyn A;Wang, Dennis;Wang, Mike;Warren, Joshua L;Weinberger, Daniel M;Arnold, Wyatt;Omer, Saad B
10.1038/s41587-020-0684-z
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Measurement of SARS-CoV-2 RNA in wastewater tracks community infection dynamics. [Abstract]: We measured severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA concentrations in primary sewage sludge in the New Haven, Connecticut, USA, metropolitan area during the Coronavirus Disease 2019 (COVID-19) ...
32,230,900
Viruses
Virology, Epidemiology, Pathogenesis, and Control of COVID-19.
The outbreak of emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (COVID-19) in China has been brought to global attention and declared a pandemic by the World Health Organization (WHO) on March 11, 2020. Scientific advancements since the pandemic of severe acute respiratory syndrome (SARS) ...
covid-19;sars-cov-2;epidemiology;pathogenesis;therapeutics
Journal Article;Review
Jin, Yuefei;Yang, Haiyan;Ji, Wangquan;Wu, Weidong;Chen, Shuaiyin;Zhang, Weiguo;Duan, Guangcai
10.3390/v12040372
[ 1, 1, 0, 1, 1, 0, 0 ]
[Title]: Virology, Epidemiology, Pathogenesis, and Control of COVID-19. [Abstract]: The outbreak of emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (COVID-19) in China has been brought to global attention and declared a pandemic by the World Health Organization (WHO) on March 11, 2020. Sci...
32,836,870
Minds Mach (Dordr)
Analysing the Combined Health, Social and Economic Impacts of the Corovanvirus Pandemic Using Agent-Based Social Simulation.
During the COVID-19 crisis there have been many difficult decisions governments and other decision makers had to make. E.g. do we go for a total lock down or keep schools open? How many people and which people should be tested? Although there are many good models from e.g. epidemiologists on the spread of the virus und...
Journal Article
Dignum, Frank;Dignum, Virginia;Davidsson, Paul;Ghorbani, Amineh;van der Hurk, Mijke;Jensen, Maarten;Kammler, Christian;Lorig, Fabian;Ludescher, Luis Gustavo;Melchior, Alexander;Mellema, Rene;Pastrav, Cezara;Vanhee, Lois;Verhagen, Harko
10.1007/s11023-020-09527-6
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Analysing the Combined Health, Social and Economic Impacts of the Corovanvirus Pandemic Using Agent-Based Social Simulation. [Abstract]: During the COVID-19 crisis there have been many difficult decisions governments and other decision makers had to make. E.g. do we go for a total lock down or keep schools ope...
33,043,249
SN Compr Clin Med
Reactivation of SARS-CoV-2 after Asymptomatic Infection while on High-Dose Corticosteroids. Case Report.
As SARS-CoV-2 and its related clinical syndrome (COVID-19) became a pandemic worldwide, questions regarding its clinical presentation, infectivity, and immune response have been the subject of investigation. We present a case of a patient previously considered recovered from nosocomially transmitted asymptomatic COVID-...
covid-19;case report;corticosteroids;rt-pcr;viral shedding
Journal Article
Patrocinio de Jesus, Rita;Silva, Raquel;Aliyeva, Elzara;Lopes, Luis;Portugalyan, Mihran;Antunes, Liliana;Diaz, Priscila;Costa, Carolina;Araujo, Ana Carolina;Coelho, Silvia;Mendes, Joao Joao;Gomes, Sara;Serra, Isabel;Freitas, Paulo
10.1007/s42399-020-00548-x
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Reactivation of SARS-CoV-2 after Asymptomatic Infection while on High-Dose Corticosteroids. Case Report. [Abstract]: As SARS-CoV-2 and its related clinical syndrome (COVID-19) became a pandemic worldwide, questions regarding its clinical presentation, infectivity, and immune response have been the subject of i...
32,794,459
J Infect Dev Ctries
Transmission dynamics of Covid-19 in Italy, Germany and Turkey considering social distancing, testing and quarantine.
INTRODUCTION: There are significant differences in the active cases and fatality rates of Covid-19 for different European countries. METHODOLOGY: The present study employs Monte Carlo based transmission growth simulations for Italy, Germany and Turkey. The probabilities of transmission at home, work and social networks...
covid-19;germany;italy;turkey;social distancing;transmission
Journal Article
Gul, Serdar;Tuncay, Kagan;Binici, Baris;Aydin, Beyazit Bestami
10.3855/jidc.12844
[ 0, 0, 1, 0, 1, 0, 0 ]
[Title]: Transmission dynamics of Covid-19 in Italy, Germany and Turkey considering social distancing, testing and quarantine. [Abstract]: INTRODUCTION: There are significant differences in the active cases and fatality rates of Covid-19 for different European countries. METHODOLOGY: The present study employs Monte Car...
32,839,951
J Neurovirol
Neurological manifestations of COVID-19: available evidences and a new paradigm.
The recent pandemic outbreak of coronavirus is pathogenic and a highly transmittable viral infection caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2). In this time of ongoing pandemic, many emerging reports suggested that the SARS-CoV-2 has inimical effects on neurological functions, and even cause...
covid-19;gene enrichment;gene prioritization;neurological damage;sars-cov-2
Journal Article;Review
Khatoon, Fatima;Prasad, Kartikay;Kumar, Vijay
10.1007/s13365-020-00895-4
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: Neurological manifestations of COVID-19: available evidences and a new paradigm. [Abstract]: The recent pandemic outbreak of coronavirus is pathogenic and a highly transmittable viral infection caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2). In this time of ongoing pandemic, many emergin...
32,972,561
JACC Clin Electrophysiol
Arrhythmias and COVID-19: A Review.
Current understanding of the impact of coronavirus disease-2019 (COVID-19) on arrhythmias continues to evolve as new data emerge. Cardiac arrhythmias are more common in critically ill COVID-19 patients. The potential mechanisms that could result in arrhythmogenesis among COVID-19 patients include hypoxia caused by dire...
covid-19;qt prolongation;sars-cov-2;arrhythmias;channelopathies;myocarditis;torsades de pointes
Journal Article;Review
Dherange, Parinita;Lang, Joshua;Qian, Pierre;Oberfeld, Blake;Sauer, William H;Koplan, Bruce;Tedrow, Usha
10.1016/j.jacep.2020.08.002
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Arrhythmias and COVID-19: A Review. [Abstract]: Current understanding of the impact of coronavirus disease-2019 (COVID-19) on arrhythmias continues to evolve as new data emerge. Cardiac arrhythmias are more common in critically ill COVID-19 patients. The potential mechanisms that could result in arrhythmogenes...
32,907,540
BMC Infect Dis
The coronavirus diseases 2019 (COVID-19) pneumonia with spontaneous pneumothorax: a case report.
BACKGROUND: The outbreak of the novel coronavirus (COVID-19) that was firstly reported in Wuhan, China, with cases now confirmed in more than 100 countries. However, COVID-19 pneumonia with spontaneous pneumothorax is unknown. CASE PRESENTATION: We reported a case of 66-year-old man infected with COVID-19, presenting w...
covid-19;pneumonia;pneumothorax;sars-cov-2 virus
Case Reports;Journal Article
Chen, Xiaoxing;Zhang, Guqin;Tang, Yueting;Peng, Zhiyong;Pan, Huaqin
10.1186/s12879-020-05384-x
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: The coronavirus diseases 2019 (COVID-19) pneumonia with spontaneous pneumothorax: a case report. [Abstract]: BACKGROUND: The outbreak of the novel coronavirus (COVID-19) that was firstly reported in Wuhan, China, with cases now confirmed in more than 100 countries. However, COVID-19 pneumonia with spontaneous ...
33,058,787
Hematol Oncol Stem Cell Ther
Bronchoalveolar lavage-based COVID-19 testing in patients with cancer.
OBJECTIVE/BACKGROUND: A few case reports in the setting of coronavirus disease 2019 (COVID-19) and multiplex polymerase chain reaction (PCR)-based assays for common respiratory pathogens have shown a higher yield of bronchoalveolar lavage (BAL) samples than upper airway specimens in immunocompromised patients. METHODS:...
bronchoalveolar lavage;cancer;coronavirus disease 2019 (covid-19);corticosteroids;hematological malignancy;immunocompromised;sars-cov-2;lymphopenia
Case Reports;Journal Article
Abid, Muhammad Bilal;Chhabra, Saurabh;Buchan, Blake;Graham, Mary Beth;Abedin, Sameem;Thapa, Bicky;D'Souza, Anita;George, Ben;Hamadani, Mehdi
10.1016/j.hemonc.2020.09.002
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Bronchoalveolar lavage-based COVID-19 testing in patients with cancer. [Abstract]: OBJECTIVE/BACKGROUND: A few case reports in the setting of coronavirus disease 2019 (COVID-19) and multiplex polymerase chain reaction (PCR)-based assays for common respiratory pathogens have shown a higher yield of bronchoalveo...
32,687,150
Clin Infect Dis
Lessons from Mass-Testing for COVID-19 in Long Term Care Facilities for the Elderly in San Francisco.
COVID-19 can cause significant mortality in the elderly in Long Term Care Facilities (LTCF). We describe four LTCF outbreaks where mass testing identified a high proportion of asymptomatic infections (4-41% in health care workers and 20-75% in residents), indicating that symptom-based screening alone is insufficient fo...
covid-19;coronavirus;elderly;health care worker;infection control;mass testing;skilled nursing facility
Journal Article
Louie, Janice K;Scott, Hyman M;DuBois, Amie;Sturtz, Natalya;Lu, Wendy;Stoltey, Juliet;Masinde, Godfred;Cohen, Stephanie;Sachdev, Darpun;Philip, Susan;Bobba, Naveena;Aragon, Tomas
10.1093/cid/ciaa1020
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Lessons from Mass-Testing for COVID-19 in Long Term Care Facilities for the Elderly in San Francisco. [Abstract]: COVID-19 can cause significant mortality in the elderly in Long Term Care Facilities (LTCF). We describe four LTCF outbreaks where mass testing identified a high proportion of asymptomatic infectio...
32,330,288
Br J Haematol
Protecting vulnerable patients with inherited anaemias from unnecessary death during the COVID-19 pandemic.
With the developing COVID-19 pandemic, patients with inherited anaemias require specific advice regarding isolation and changes to usual treatment schedules. The National Haemoglobinopathy Panel (NHP) has issued guidance on the care of patients with sickle cell disease, thalassaemia, Diamond Blackfan anaemia (DBA), con...
Journal Article
Roy, Noemi B A;Telfer, Paul;Eleftheriou, Perla;de la Fuente, Josu;Drasar, Emma;Shah, Farrukh;Roberts, David;Atoyebi, Wale;Trompeter, Sara;Layton, D Mark;Lugthart, Sanne;Stuart-Smith, Sara;Chakravorty, Subarna;Wright, Josh;Porter, John;Inusa, Baba;Howard, Jo
10.1111/bjh.16687
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Protecting vulnerable patients with inherited anaemias from unnecessary death during the COVID-19 pandemic. [Abstract]: With the developing COVID-19 pandemic, patients with inherited anaemias require specific advice regarding isolation and changes to usual treatment schedules. The National Haemoglobinopathy Pa...
32,846,196
Virus Res
Prospect of SARS-CoV-2 spike protein: Potential role in vaccine and therapeutic development.
The recent outbreak of the betacoronavirus SARS-CoV-2 has become a significant concern to public health care worldwide. As of August 19, 2020, more than 22,140,472 people are infected, and over 781,135 people have died due to this deadly virus. In the USA alone, over 5,482,602 people are currently infected, and more th...
covid-19;sars-cov-2;spike protein;therapeutic;vaccine
Journal Article;Research Support, N.I.H., Extramural;Review
Samrat, Subodh Kumar;Tharappel, Anil M;Li, Zhong;Li, Hongmin
10.1016/j.virusres.2020.198141
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Prospect of SARS-CoV-2 spike protein: Potential role in vaccine and therapeutic development. [Abstract]: The recent outbreak of the betacoronavirus SARS-CoV-2 has become a significant concern to public health care worldwide. As of August 19, 2020, more than 22,140,472 people are infected, and over 781,135 peop...
32,330,439
Lancet Infect Dis
Connecting clusters of COVID-19: an epidemiological and serological investigation.
BACKGROUND: Elucidation of the chain of disease transmission and identification of the source of coronavirus disease 2019 (COVID-19) infections are crucial for effective disease containment. We describe an epidemiological investigation that, with use of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serol...
Journal Article;Research Support, Non-U.S. Gov't
Yong, Sarah Ee Fang;Anderson, Danielle Elizabeth;Wei, Wycliffe E;Pang, Junxiong;Chia, Wan Ni;Tan, Chee Wah;Teoh, Yee Leong;Rajendram, Priyanka;Toh, Matthias Paul Han Sim;Poh, Cuiqin;Koh, Valerie T J;Lum, Joshua;Suhaimi, Nur-Afidah Md;Chia, Po Ying;Chen, Mark I-Cheng;Vasoo, Shawn;Ong, Benjamin;Leo, Yee Sin;Wang, Linfa;L...
10.1016/S1473-3099(20)30273-5
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: Connecting clusters of COVID-19: an epidemiological and serological investigation. [Abstract]: BACKGROUND: Elucidation of the chain of disease transmission and identification of the source of coronavirus disease 2019 (COVID-19) infections are crucial for effective disease containment. We describe an epidemiolo...
32,790,733
PLoS One
Hydroxychloroquine and tocilizumab therapy in COVID-19 patients-An observational study.
Hydroxychloroquine has been touted as a potential COVID-19 treatment. Tocilizumab, an inhibitor of IL-6, has also been proposed as a treatment of critically ill patients. In this retrospective observational cohort study drawn from electronic health records we sought to describe the association between mortality and hyd...
Journal Article;Multicenter Study;Observational Study
Ip, Andrew;Berry, Donald A;Hansen, Eric;Goy, Andre H;Pecora, Andrew L;Sinclaire, Brittany A;Bednarz, Urszula;Marafelias, Michael;Berry, Scott M;Berry, Nicholas S;Mathura, Shivam;Sawczuk, Ihor S;Biran, Noa;Go, Ronaldo C;Sperber, Steven;Piwoz, Julia A;Balani, Bindu;Cicogna, Cristina;Sebti, Rani;Zuckerman, Jerry;Rose, Kei...
10.1371/journal.pone.0237693
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Hydroxychloroquine and tocilizumab therapy in COVID-19 patients-An observational study. [Abstract]: Hydroxychloroquine has been touted as a potential COVID-19 treatment. Tocilizumab, an inhibitor of IL-6, has also been proposed as a treatment of critically ill patients. In this retrospective observational coho...
32,823,907
Life (Basel)
Molecular Epidemiology Analysis of SARS-CoV-2 Strains Circulating in Romania during the First Months of the Pandemic.
BACKGROUND: The spread of SARS-CoV-2 generated an unprecedented global public health crisis. Soon after Asia, Europe was seriously affected. Many countries, including Romania, adopted lockdown measures to limit the outbreak. AIM: We performed a molecular epidemiology analysis of SARS-CoV-2 viral strains circulating in ...
romania;sars-cov-2;wgs;coronavirus;mutations;outbreak;pandemic;phylogenetic analysis
Journal Article
Surleac, Marius;Banica, Leontina;Casangiu, Corina;Cotic, Marius;Florea, Dragos;Sandulescu, Oana;Milu, Petre;Streinu-Cercel, Anca;Vlaicu, Ovidiu;Paraskevis, Dimitrios;Paraschiv, Simona;Otelea, Dan
10.3390/life10080152
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Molecular Epidemiology Analysis of SARS-CoV-2 Strains Circulating in Romania during the First Months of the Pandemic. [Abstract]: BACKGROUND: The spread of SARS-CoV-2 generated an unprecedented global public health crisis. Soon after Asia, Europe was seriously affected. Many countries, including Romania, adopt...
33,021,717
J Gen Intern Med
Comparing Associations of State Reopening Strategies with COVID-19 Burden.
BACKGROUND: The novel coronavirus disease 2019 (COVID-19) infected over 5 million United States (US) residents resulting in more than 180,000 deaths by August 2020. To mitigate transmission, most states ordered shelter-in-place orders in March and reopening strategies varied. OBJECTIVE: To estimate excess COVID-19 case...
Journal Article
Kaufman, Brystana G;Whitaker, Rebecca;Mahendraratnam, Nirosha;Smith, Valerie A;McClellan, Mark B
10.1007/s11606-020-06277-0
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Comparing Associations of State Reopening Strategies with COVID-19 Burden. [Abstract]: BACKGROUND: The novel coronavirus disease 2019 (COVID-19) infected over 5 million United States (US) residents resulting in more than 180,000 deaths by August 2020. To mitigate transmission, most states ordered shelter-in-pl...
32,917,282
Hum Genomics
Genetic variants of the human host influencing the coronavirus-associated phenotypes (SARS, MERS and COVID-19): rapid systematic review and field synopsis.
The COVID-19 pandemic has strengthened the interest in the biological mechanisms underlying the complex interplay between infectious agents and the human host. The spectrum of phenotypes associated with the SARS-CoV-2 infection, ranging from the absence of symptoms to severe systemic complications, raised the question ...
covid-19;coronavirus;genetic association;genetic susceptibility;genomic biomarker;genotype;human host;polymorphism
Journal Article;Meta-Analysis;Research Support, Non-U.S. Gov't;Review;Systematic Review
Di Maria, Emilio;Latini, Andrea;Borgiani, Paola;Novelli, Giuseppe
10.1186/s40246-020-00280-6
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Genetic variants of the human host influencing the coronavirus-associated phenotypes (SARS, MERS and COVID-19): rapid systematic review and field synopsis. [Abstract]: The COVID-19 pandemic has strengthened the interest in the biological mechanisms underlying the complex interplay between infectious agents and...
32,202,240
Clin Exp Rheumatol
COVID-19, cytokines and immunosuppression: what can we learn from severe acute respiratory syndrome?
A severe outbreak of coronavirus disease 2019 (COVID-19) emerged in China in December 2019, and spread so rapidly that more than 200,000 cases have so far been reported worldwide; on January 30, 2020, the WHO declared it the sixth public health emergency of international concern. The two previously reported coronavirus...
Journal Article;Review
Sarzi-Puttini, Piercarlo;Giorgi, Valeria;Sirotti, Silvia;Marotto, Daniela;Ardizzone, Sandro;Rizzardini, Giuliano;Antinori, Spinello;Galli, Massimo
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: COVID-19, cytokines and immunosuppression: what can we learn from severe acute respiratory syndrome? [Abstract]: A severe outbreak of coronavirus disease 2019 (COVID-19) emerged in China in December 2019, and spread so rapidly that more than 200,000 cases have so far been reported worldwide; on January 30, 202...
32,716,897
J Med Internet Res
Chinese Public's Engagement in Preventive and Intervening Health Behaviors During the Early Breakout of COVID-19: Cross-Sectional Study.
BACKGROUND: Since January 2020, the coronavirus disease (COVID-19) swept over China and then the world, causing a global public health crisis. People's adoption of preventive and intervening behaviors is critical in curbing the spread of the virus. OBJECTIVE: The aim of this study is to evaluate Chinese people's adopti...
covid-19;china;behavior;cross-sectional;health literacy;intervening health behaviors;prevention;preventive health behaviors;psychosocial
Journal Article
Niu, Zhaomeng;Wang, Tingting;Hu, Pengwei;Mei, Jing;Tang, Zhihan
10.2196/19995
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Chinese Public's Engagement in Preventive and Intervening Health Behaviors During the Early Breakout of COVID-19: Cross-Sectional Study. [Abstract]: BACKGROUND: Since January 2020, the coronavirus disease (COVID-19) swept over China and then the world, causing a global public health crisis. People's adoption o...
33,023,916
J Investig Med
COVID-19 epidemic outside China: 34 founders and exponential growth.
COVID-19 raised tension both within China and internationally. Here, we used mathematical modeling to predict the trend of patient diagnosis outside China in future, with the aim of easing anxiety regarding the emergent situation. According to all diagnosis number from WHO website and combining with the transmission mo...
disease management
Journal Article;Research Support, Non-U.S. Gov't
Li, Yi;Liang, Meng;Yin, Xianhong;Liu, Xiaoyu;Hao, Meng;Hu, Zixin;Wang, Yi;Jin, Li
10.1136/jim-2020-001491
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: COVID-19 epidemic outside China: 34 founders and exponential growth. [Abstract]: COVID-19 raised tension both within China and internationally. Here, we used mathematical modeling to predict the trend of patient diagnosis outside China in future, with the aim of easing anxiety regarding the emergent situation....
32,926,572
Pediatr Pulmonol
Pediatric lung imaging features of COVID-19: A systematic review and meta-analysis.
RATIONALE: Pediatric COVID-19 studies have been mostly restricted to case reports and small case series, which have prevented the identification of specific pediatric lung disease patterns in COVID-19. The overarching goal of this systematic review and meta-analysis is to provide the first comprehensive summary of the ...
sars-cov-2;lung ct scan;meta-analysis;pediatric covid-19
Journal Article;Meta-Analysis;Research Support, N.I.H., Extramural;Systematic Review
Nino, Gustavo;Zember, Jonathan;Sanchez-Jacob, Ramon;Gutierrez, Maria J;Sharma, Karun;Linguraru, Marius George
10.1002/ppul.25070
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Pediatric lung imaging features of COVID-19: A systematic review and meta-analysis. [Abstract]: RATIONALE: Pediatric COVID-19 studies have been mostly restricted to case reports and small case series, which have prevented the identification of specific pediatric lung disease patterns in COVID-19. The overarchi...
32,353,978
Int J Mol Sci
Structural and Evolutionary Analysis Indicate That the SARS-CoV-2 Mpro Is a Challenging Target for Small-Molecule Inhibitor Design.
The novel coronavirus whose outbreak took place in December 2019 continues to spread at a rapid rate worldwide. In the absence of an effective vaccine, inhibitor repurposing or de novo drug design may offer a longer-term strategy to combat this and future infections due to similar viruses. Here, we report on detailed c...
covid-19;sars-cov;sars-cov-2;coronavirus;drug design;evolutionary analysis;ligand tracking approach;molecular dynamics simulations;small-molecule inhibitors
Journal Article
Bzowka, Maria;Mitusinska, Karolina;Raczynska, Agata;Samol, Aleksandra;Tuszynski, Jack A;Gora, Artur
10.3390/ijms21093099
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Structural and Evolutionary Analysis Indicate That the SARS-CoV-2 Mpro Is a Challenging Target for Small-Molecule Inhibitor Design. [Abstract]: The novel coronavirus whose outbreak took place in December 2019 continues to spread at a rapid rate worldwide. In the absence of an effective vaccine, inhibitor repur...
32,575,114
Clin Infect Dis
Clinical Presentation and Outcomes of Pregnant Women with COVID-19: A Systematic Review and Meta-Analysis.
INTRODUCTION: Descriptions of coronavirus disease-2019 (COVID-19) have focused on the non-pregnant adult population. This study aims to describe the clinical characteristics and perinatal outcomes of COVID-19 in pregnancy. METHODS: We searched databases from December 2019 to April 30th, 2020. Eligible studies reported ...
coronavirus;neonates;pregnant;transmission
Journal Article;Meta-Analysis;Systematic Review
Matar, Reem;Alrahmani, Layan;Monzer, Nasser;Debiane, Labib G;Berbari, Elie;Fares, Jawad;Fitzpatrick, Fidelma;Murad, Mohammad H
10.1093/cid/ciaa828
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical Presentation and Outcomes of Pregnant Women with COVID-19: A Systematic Review and Meta-Analysis. [Abstract]: INTRODUCTION: Descriptions of coronavirus disease-2019 (COVID-19) have focused on the non-pregnant adult population. This study aims to describe the clinical characteristics and perinatal outc...
32,660,556
BMC Res Notes
Age, source, and future risk of COVID-19 infections in two settings of Hong Kong and Singapore.
OBJECTIVE: To explore and compare the age, source and future risk of COVID-19 infection in Hong Kong SAR China and Singapore as of March 5, 2020. RESULTS: We find significant difference in age patterns of confirmed cases in these 2 localities early in the pandemic. CONCLUSION: We highlight the potential importance of p...
age structure;covid-19;hong kong;singapore
Journal Article
Zhu, Shuying;Tao, Jun;Gao, Huizhi;He, Daihai
10.1186/s13104-020-05178-z
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Age, source, and future risk of COVID-19 infections in two settings of Hong Kong and Singapore. [Abstract]: OBJECTIVE: To explore and compare the age, source and future risk of COVID-19 infection in Hong Kong SAR China and Singapore as of March 5, 2020. RESULTS: We find significant difference in age patterns o...
32,733,979
Arch Bone Jt Surg
Bone in the Time of Corona: Suggestions for Managing Pediatric Orthopaedics Conditions in a Resource-limited Environment during the COVID-19 Pandemic.
The outbreak of a novel coronavirus, referred to as coronavirus disease-19 (COVID-19), with its sentinel case in Wuhan, China, in December 2019, has spread rapidly around the globe. On March 11, 2020, the World Health Organization (WHO) declared COVID-19 a worldwide pandemic, which led to most countries implementing so...
covid-19;clubfoot;fractures;pediatric orthopaedics;pediatrics;sars-cov2
Journal Article;Review
Baghdadi, Soroush;Nabian, Mohammad Hossein;Baghdadi, Taghi
10.22038/ABJS.2020.47715.2340
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Bone in the Time of Corona: Suggestions for Managing Pediatric Orthopaedics Conditions in a Resource-limited Environment during the COVID-19 Pandemic. [Abstract]: The outbreak of a novel coronavirus, referred to as coronavirus disease-19 (COVID-19), with its sentinel case in Wuhan, China, in December 2019, has...
33,063,540
Ann Med
Admission hyperglycaemia as a predictor of mortality in patients hospitalized with COVID-19 regardless of diabetes status: data from the Spanish SEMI-COVID-19 Registry.
BACKGROUND: Hyperglycaemia has emerged as an important risk factor for death in coronavirus disease 2019 (COVID-19). The aim of this study was to evaluate the association between blood glucose (BG) levels and in-hospital mortality in non-critically patients hospitalized with COVID-19. METHODS: This is a retrospective m...
covid-19;sars-cov-2;diabetes;hyperglycaemia;mortality
Journal Article;Research Support, Non-U.S. Gov't
Carrasco-Sanchez, Francisco Javier;Lopez-Carmona, M feminine Dolores;Martinez-Marcos, Francisco Javier;Perez-Belmonte, Luis M;Hidalgo-Jimenez, Alicia;Buonaiuto, Veronica;Suarez Fernandez, Carmen;Freire Castro, Santiago Jesus;Luordo, Davide;Pesqueira Fontan, Paula Maria;Blazquez Encinar, Julio Cesar;Magallanes Gamboa, J...
10.1080/07853890.2020.1836566
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Admission hyperglycaemia as a predictor of mortality in patients hospitalized with COVID-19 regardless of diabetes status: data from the Spanish SEMI-COVID-19 Registry. [Abstract]: BACKGROUND: Hyperglycaemia has emerged as an important risk factor for death in coronavirus disease 2019 (COVID-19). The aim of th...
32,876,206
Rev Peru Med Exp Salud Publica
Estimated conditions to control the covid-19 pandemic in peruvian pre- and post-quarantine scenarios.
OBJECTIVES: To determine the probability of controlling the outbreak of COVID-19 in Peru, in a pre- and post-quarantine scenario using mathematical simulation models. MATERIALS AND METHODS: Outbreak si mulations for the COVID-19 pandemic are performed, using stochastic equations under the following assumptions: a pre-q...
Journal Article
Huamani, Charles;Timana-Ruiz, Raul;Pinedo, Jairo;Perez, Jhelly;Vasquez, Luis
10.17843/rpmesp.2020.372.5405
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: Estimated conditions to control the covid-19 pandemic in peruvian pre- and post-quarantine scenarios. [Abstract]: OBJECTIVES: To determine the probability of controlling the outbreak of COVID-19 in Peru, in a pre- and post-quarantine scenario using mathematical simulation models. MATERIALS AND METHODS: Outbrea...
32,534,506
Iran J Allergy Asthma Immunol
Bradykinin as a Probable Aspect in SARS-Cov-2 Scenarios: Is Bradykinin Sneaking out of Our Sight?
The new virus SARS-CoV-2 is savagely spreading out over the world. The biologic studies show that the target receptor for the virus might be angiotensin-converting enzyme 2 (ACE2). This peptide is responsible for converting angiotensin II (Ang II), which is a profoundly active peptide, into Ang 1-7 with quite a balanci...
angiotensin-converting enzyme 2;aprotinin;bradykinin;icatibant;sars-cov-2
Journal Article
Ghahestani, Seyed-Mohammad;Mahmoudi, Javad;Hajebrahimi, Sakineh;Sioofy-Khojine, Amir-Babak;Salehi-Pourmehr, Hanieh;Sadeghi-Ghyassi, Fatemeh;Mostafaei, Hadi
10.18502/ijaai.v19i(s1.r1).2850
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Bradykinin as a Probable Aspect in SARS-Cov-2 Scenarios: Is Bradykinin Sneaking out of Our Sight? [Abstract]: The new virus SARS-CoV-2 is savagely spreading out over the world. The biologic studies show that the target receptor for the virus might be angiotensin-converting enzyme 2 (ACE2). This peptide is resp...
32,906,733
Molecules
The New Coronavirus (SARS-CoV-2): A Comprehensive Review on Immunity and the Application of Bioinformatics and Molecular Modeling to the Discovery of Potential Anti-SARS-CoV-2 Agents.
On March 11, 2020, the World Health Organization (WHO) officially declared the outbreak caused by the new coronavirus (SARS-CoV-2) a pandemic. The rapid spread of the disease surprised the scientific and medical community. Based on the latest reports, news, and scientific articles published, there is no doubt that the ...
sars-cov-2;bioinformatics;drug discovery;infectious disease;innate immunity;molecular modeling;treatment
Journal Article;Review
Villas-Boas, Gustavo R;Rescia, Vanessa C;Paes, Marina M;Lavorato, Stefania N;Magalhaes-Filho, Manoel F de;Cunha, Mila S;Simoes, Rafael da C;Lacerda, Roseli B de;Freitas-Junior, Renilson S de;Ramos, Bruno H da S;Mapeli, Ana M;Henriques, Matheus da S T;Freitas, William R de;Lopes, Luiz A F;Oliveira, Luiz G R;Silva, Jonat...
10.3390/molecules25184086
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: The New Coronavirus (SARS-CoV-2): A Comprehensive Review on Immunity and the Application of Bioinformatics and Molecular Modeling to the Discovery of Potential Anti-SARS-CoV-2 Agents. [Abstract]: On March 11, 2020, the World Health Organization (WHO) officially declared the outbreak caused by the new coronavir...
32,872,734
Korean J Intern Med
Clinical characteristics of coronavirus disease 2019 patients with diarrhea in Daegu.
BACKGROUND/AIMS: Coronavirus disease 2019 (COVID-19) can reportedly cause gastrointestinal symptoms. Therefore, we investigated the clinical characteristics of COVID-19 patients with diarrhea. METHODS: We included 118 COVID-19 patients admitted to a single hospital from February 20 to March 31, 2020. Medical records wi...
covid-19;diarrhea;mortality;shock, septic
Journal Article;Research Support, Non-U.S. Gov't
Kang, Min Kyu;Kim, Kyeong Ok;Kim, Min Cheol;Cho, Joon Hyun;Kim, Sung Bum;Park, Jung Gil;Kim, Kook Hyun;Lee, See Hyung;Jang, Byung Ik;Kim, Tae Nyeun
10.3904/kjim.2020.196
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical characteristics of coronavirus disease 2019 patients with diarrhea in Daegu. [Abstract]: BACKGROUND/AIMS: Coronavirus disease 2019 (COVID-19) can reportedly cause gastrointestinal symptoms. Therefore, we investigated the clinical characteristics of COVID-19 patients with diarrhea. METHODS: We included...
32,610,564
Diagnostics (Basel)
COVID-19 as a Vascular Disease: Lesson Learned from Imaging and Blood Biomarkers.
COVID-19, a disease initially thought to be prominently an interstitial pneumonia with varying degrees of severity, can be considered a vascular disease with regards to serious complications and causes of mortality. Quite recently, blood clots have emerged as the common factor unifying many of the symptoms initially at...
covid-19;d-dimer;sars-cov-2;contrast-enhanced ultrasound;deep vein thrombosis;ischemia;lung ultrasound;pulmonary embolism.;thrombosis;ultrasound;vascular biomarkers;venous thromboembolism
Editorial
Zamboni, Paolo
10.3390/diagnostics10070440
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: COVID-19 as a Vascular Disease: Lesson Learned from Imaging and Blood Biomarkers. [Abstract]: COVID-19, a disease initially thought to be prominently an interstitial pneumonia with varying degrees of severity, can be considered a vascular disease with regards to serious complications and causes of mortality. Q...
32,880,993
J Med Virol
Predictive effects of IgA and IgG combination to assess pulmonary exudation progression in COVID-19 patients.
Our study intended to longitudinally explore the prediction effect of immunoglobulin A (IgA) on pulmonary exudation progression in COVID-19 patients. The serum IgA was tested with chemiluminescence method. Autoregressive moving average model was used to extrapolate the IgA levels before hospital admission. The positive...
covid-19;iga;igg;prediction effects
Journal Article;Research Support, Non-U.S. Gov't
Xue, Mingshan;Zhang, Teng;Hu, Haisheng;Huang, Zhifeng;Zhen, Yingjie;Liang, Yueting;Zeng, Yifeng;Jin, Tengchuan;Zhou, Luqian;Zhang, Xiaohua D;Sun, Baoqing
10.1002/jmv.26437
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Predictive effects of IgA and IgG combination to assess pulmonary exudation progression in COVID-19 patients. [Abstract]: Our study intended to longitudinally explore the prediction effect of immunoglobulin A (IgA) on pulmonary exudation progression in COVID-19 patients. The serum IgA was tested with chemilumi...
33,023,561
BMC Public Health
Why crowding matters in the time of COVID-19 pandemic? - a lesson from the carnival effect on the 2017/2018 influenza epidemic in the Netherlands.
BACKGROUND: To evaluate the association between crowding and transmission of viral respiratory infectious diseases, we investigated the change in transmission patterns of influenza and COVID-19 before and after a mass gathering event (i.e., carnival) in the Netherlands. METHODS: Information on individual hospitalizatio...
covid-19;epidemiology;influenza;mass gathering medicine
Journal Article
Chen, Qingui;Toorop, Myrthe M A;de Boer, Mark G J;Rosendaal, Frits R;Lijfering, Willem M
10.1186/s12889-020-09612-6
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Why crowding matters in the time of COVID-19 pandemic? - a lesson from the carnival effect on the 2017/2018 influenza epidemic in the Netherlands. [Abstract]: BACKGROUND: To evaluate the association between crowding and transmission of viral respiratory infectious diseases, we investigated the change in transm...
32,487,876
Curr Opin Clin Nutr Metab Care
Nutrition in times of Covid-19, how to trust the deluge of scientific information.
PURPOSE OF REVIEW: The Covid-19 pandemic has daunted the world with its enormous impact on healthcare, economic recession, and psychological distress. Nutrition is an integral part of every person life care, and should also be mandatorily integrated to patient care under the Covid-19 pandemic. It is crucial to understa...
Journal Article;Review
Correia, Maria Isabel T D
10.1097/MCO.0000000000000666
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Nutrition in times of Covid-19, how to trust the deluge of scientific information. [Abstract]: PURPOSE OF REVIEW: The Covid-19 pandemic has daunted the world with its enormous impact on healthcare, economic recession, and psychological distress. Nutrition is an integral part of every person life care, and shou...
33,059,091
Clin Microbiol Infect
Overall decrease in SARS-CoV-2 viral load and reduction in clinical burden: the experience of a hospital in northern Italy.
OBJECTIVES: In Italy the burden of patients with coronavirus disease 2019 (COVID-19) gradually decreased from March to the end of May. In this work we aimed to evaluate a possible association between the severity of clinical manifestations and viral load over time during the epidemiological transition from high-to low-...
covid-19;coronavirus;coronavirus disease 2019;sars-cov-2;viral load
Journal Article
Piubelli, Chiara;Deiana, Michela;Pomari, Elena;Silva, Ronaldo;Bisoffi, Zeno;Formenti, Fabio;Perandin, Francesca;Gobbi, Federico;Buonfrate, Dora
10.1016/j.cmi.2020.10.006
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Overall decrease in SARS-CoV-2 viral load and reduction in clinical burden: the experience of a hospital in northern Italy. [Abstract]: OBJECTIVES: In Italy the burden of patients with coronavirus disease 2019 (COVID-19) gradually decreased from March to the end of May. In this work we aimed to evaluate a poss...
33,058,755
Cell
A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model.
The emergence of SARS-CoV-2 led to pandemic spread of coronavirus disease 2019 (COVID-19), manifesting with respiratory symptoms and multi-organ dysfunction. Detailed characterization of virus-neutralizing antibodies and target epitopes is needed to understand COVID-19 pathophysiology and guide immunization strategies....
covid-19;sars-cov-2;autoreactivity;crystal structures;hamster model;monoclonal antibody;neutralizing antibody;post-exposure;self-antigens;self-reactivity
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't;Research Support, U.S. Gov't, Non-P.H.S.
Kreye, Jakob;Reincke, S Momsen;Kornau, Hans-Christian;Sanchez-Sendin, Elisa;Corman, Victor Max;Liu, Hejun;Yuan, Meng;Wu, Nicholas C;Zhu, Xueyong;Lee, Chang-Chun D;Trimpert, Jakob;Holtje, Markus;Dietert, Kristina;Stoffler, Laura;von Wardenburg, Niels;van Hoof, Scott;Homeyer, Marie A;Hoffmann, Julius;Abdelgawad, Azza;Gru...
10.1016/j.cell.2020.09.049
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model. [Abstract]: The emergence of SARS-CoV-2 led to pandemic spread of coronavirus disease 2019 (COVID-19), manifesting with respiratory symptoms and multi-organ dysfunction. Detailed characterization of vi...
32,396,947
Am J Perinatol
A Proposed Plan for Prenatal Care to Minimize Risks of COVID-19 to Patients and Providers: Focus on Hypertensive Disorders of Pregnancy.
Hypertensive disorders are the most common medical complications of pregnancy and a major cause of maternal and perinatal morbidity and death. The detection of elevated blood pressure during pregnancy is one of the cardinal aspects of optimal antenatal care. With the outbreak of novel coronavirus disease 2019 (COVID-19...
Journal Article
Barton, John R;Saade, George R;Sibai, Baha M
10.1055/s-0040-1710538
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: A Proposed Plan for Prenatal Care to Minimize Risks of COVID-19 to Patients and Providers: Focus on Hypertensive Disorders of Pregnancy. [Abstract]: Hypertensive disorders are the most common medical complications of pregnancy and a major cause of maternal and perinatal morbidity and death. The detection of el...
32,752,217
Foods
Food and COVID-19: Preventive/Co-therapeutic Strategies Explored by Current Clinical Trials and in Silico Studies.
Foods, food ingredients, and their balanced consumption are recognized to have an important role in achieving or maintaining a state of wellbeing by acting as carriers of functional components and bioactive molecules. However, the potential contribution of foods to consumers' health has so far only been partially explo...
covid-19;sars-cov-2;food;immune system;in silico study;micronutrient clinical trial;protein interaction
Journal Article;Review
Di Matteo, Giacomo;Spano, Mattia;Grosso, Michela;Salvo, Andrea;Ingallina, Cinzia;Russo, Mariateresa;Ritieni, Alberto;Mannina, Luisa
10.3390/foods9081036
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Food and COVID-19: Preventive/Co-therapeutic Strategies Explored by Current Clinical Trials and in Silico Studies. [Abstract]: Foods, food ingredients, and their balanced consumption are recognized to have an important role in achieving or maintaining a state of wellbeing by acting as carriers of functional co...
32,687,997
Sci Total Environ
SARS-CoV-2 in the environment: Modes of transmission, early detection and potential role of pollutions.
The coronavirus disease 2019 (COVID-19) is spreading globally having a profound effect on lives of millions of people, causing worldwide economic disruption. Curbing the spread of COVID-19 and future pandemics may be accomplished through understanding the environmental context of severe acute respiratory syndrome coron...
air pollution;covid-19;environmental context;modes of transmission;solid waste;wastewater-based epidemiology
Journal Article;Review
Al Huraimel, Khaled;Alhosani, Mohamed;Kunhabdulla, Shabana;Stietiya, Mohammed Hashem
10.1016/j.scitotenv.2020.140946
[ 0, 0, 1, 0, 1, 0, 0 ]
[Title]: SARS-CoV-2 in the environment: Modes of transmission, early detection and potential role of pollutions. [Abstract]: The coronavirus disease 2019 (COVID-19) is spreading globally having a profound effect on lives of millions of people, causing worldwide economic disruption. Curbing the spread of COVID-19 and fu...
32,473,952
Infect Dis Health
SARS-CoV-2: The viral shedding vs infectivity dilemma.
Since December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected over four million people worldwide. There are multiple reports of prolonged viral shedding in people infected with SARS-CoV-2 but the presence of viral RNA on a test does not necessarily correlate with infectivity. The durati...
covid-19;public health;sars-cov-2;transmission;virus shedding
Journal Article
Widders, Arabella;Broom, Alex;Broom, Jennifer
10.1016/j.idh.2020.05.002
[ 0, 1, 1, 0, 1, 0, 0 ]
[Title]: SARS-CoV-2: The viral shedding vs infectivity dilemma. [Abstract]: Since December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected over four million people worldwide. There are multiple reports of prolonged viral shedding in people infected with SARS-CoV-2 but the presence of vir...
32,810,285
Eur J Clin Invest
Efficacy of various treatment modalities for nCOV-2019: A systematic review and meta-analysis.
BACKGROUND: Several therapeutic agents have been investigated for treatment of novel coronavirus 2019 (nCOV-2019). We conducted a systematic review and meta-analysis to assess the efficacy of various treatment modalities in nCOV-2019 patients. METHODS: A literature search was conducted before 29 June 2020 in PubMed, Go...
humans;interventions;ncov-2019;novel coronavirus 2019;treatments
Comparative Study;Journal Article;Meta-Analysis;Systematic Review
Misra, Shubham;Nath, Manabesh;Hadda, Vijay;Vibha, Deepti
10.1111/eci.13383
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Efficacy of various treatment modalities for nCOV-2019: A systematic review and meta-analysis. [Abstract]: BACKGROUND: Several therapeutic agents have been investigated for treatment of novel coronavirus 2019 (nCOV-2019). We conducted a systematic review and meta-analysis to assess the efficacy of various trea...
32,474,631
Eur Radiol
Relationship between clinical types and radiological subgroups defined by latent class analysis in 2019 novel coronavirus pneumonia caused by SARS-CoV-2.
OBJECTIVES: To investigate whether meaningful subgroups sharing the CT features of patients with COVID-19 pneumonia could be identified using latent class analysis (LCA) and explore the relationship between the LCA-derived subgroups and clinical types. METHODS: This retrospective review included 499 patients with confi...
coronavirus infections;pneumonia, latent class analysis;tomography, x-ray computed
Journal Article
Fang, Xu;Li, Xiao;Bian, Yun;Ji, Xiang;Lu, Jianping
10.1007/s00330-020-06973-9
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Relationship between clinical types and radiological subgroups defined by latent class analysis in 2019 novel coronavirus pneumonia caused by SARS-CoV-2. [Abstract]: OBJECTIVES: To investigate whether meaningful subgroups sharing the CT features of patients with COVID-19 pneumonia could be identified using lat...
32,353,545
Int J Infect Dis
Persistence of intestinal SARS-CoV-2 infection in patients with COVID-19 leads to re-admission after pneumonia resolved.
The current reports of COVID-19 focus on the respiratory system, however, intestinal infections caused by SARS-CoV-2 are also worthy of attention. This paper reported persistence of intestinal SARS-CoV-2 infection leads to re-admission after pneumonia resolved in three cases with COVID-19.
covid-19;environmental sars-cov-2 contamination;intestinal infection;sars-cov-2;viral excretion of sars-cov-2
Case Reports
Wang, Xiaorong;Zhou, Yaya;Jiang, Nanchuan;Zhou, Qiong;Ma, Wan-Li
10.1016/j.ijid.2020.04.063
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Persistence of intestinal SARS-CoV-2 infection in patients with COVID-19 leads to re-admission after pneumonia resolved. [Abstract]: The current reports of COVID-19 focus on the respiratory system, however, intestinal infections caused by SARS-CoV-2 are also worthy of attention. This paper reported persistence...
32,784,239
BMJ Case Rep
Severe pre-eclampsia complicated by acute fatty liver disease of pregnancy, HELLP syndrome and acute kidney injury following SARS-CoV-2 infection.
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has presented many diagnostic challenges and uncertainties. Little is known about common pathologies complicating pregnancy and how their behaviour is modified by the presence of SARS-CoV-2. Pregnancy itself can alter the body's response to viral...
haematology (incl blood transfusion);hypertension;liver disease;obstetrics and gynaecology;pregnancy
Case Reports;Journal Article
Ahmed, Irshad;Eltaweel, Nashwa;Antoun, Lina;Rehal, Anoop
10.1136/bcr-2020-237521
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Severe pre-eclampsia complicated by acute fatty liver disease of pregnancy, HELLP syndrome and acute kidney injury following SARS-CoV-2 infection. [Abstract]: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has presented many diagnostic challenges and uncertainties. Little is known ab...
32,347,743
Circ Arrhythm Electrophysiol
Effect of Chloroquine, Hydroxychloroquine, and Azithromycin on the Corrected QT Interval in Patients With SARS-CoV-2 Infection.
BACKGROUND: The novel SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is responsible for the global coronavirus disease 2019 pandemic. Small studies have shown a potential benefit of chloroquine/hydroxychloroquine+/-azithromycin for the treatment of coronavirus disease 2019. Use of these medications alone,...
covid-19;qt prolongation;azithromycin;chloroquine;hydroxychloroquine;pandemic
Journal Article;Multicenter Study;Observational Study
Saleh, Moussa;Gabriels, James;Chang, David;Soo Kim, Beom;Mansoor, Amtul;Mahmood, Eitezaz;Makker, Parth;Ismail, Haisam;Goldner, Bruce;Willner, Jonathan;Beldner, Stuart;Mitra, Raman;John, Roy;Chinitz, Jason;Skipitaris, Nicholas;Mountantonakis, Stavros;Epstein, Laurence M
10.1161/CIRCEP.120.008662
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Effect of Chloroquine, Hydroxychloroquine, and Azithromycin on the Corrected QT Interval in Patients With SARS-CoV-2 Infection. [Abstract]: BACKGROUND: The novel SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is responsible for the global coronavirus disease 2019 pandemic. Small studies have show...
32,895,799
Eur Arch Otorhinolaryngol
In vitro comparison of surgical techniques in times of the SARS-CoV-2 pandemic: electrocautery generates more droplets and aerosol than laser surgery or drilling.
INTRODUCTION: Based on current knowledge, the SARS-CoV-2 is transmitted via droplet, aerosols and smear infection. Due to a confirmed high virus load in the upper respiratory tract of COVID-19 patients, there is a potential risk of infection for health care professionals when performing surgical procedures in this area...
aerosol;airborne infection;particle;sars-cov-2
Journal Article
Guderian, Daniela B;Loth, Andreas G;Weiss, Roxanne;Diensthuber, Marc;Stover, Timo;Leinung, Martin
10.1007/s00405-020-06330-y
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: In vitro comparison of surgical techniques in times of the SARS-CoV-2 pandemic: electrocautery generates more droplets and aerosol than laser surgery or drilling. [Abstract]: INTRODUCTION: Based on current knowledge, the SARS-CoV-2 is transmitted via droplet, aerosols and smear infection. Due to a confirmed hi...
32,945,846
Clin Infect Dis
Risk Factors for COVID-19-associated hospitalization: COVID-19-Associated Hospitalization Surveillance Network and Behavioral Risk Factor Surveillance System.
BACKGROUND: Data on risk factors for COVID-19-associated hospitalization are needed to guide prevention efforts and clinical care. We sought to identify factors independently associated with COVID-19-associated hospitalizations. METHODS: U.S. community-dwelling adults (>/=18 years) hospitalized with laboratory-confirme...
covid-19;epidemiology;hospitalization;risk factors;surveillance
Journal Article
Ko, Jean Y;Danielson, Melissa L;Town, Machell;Derado, Gordana;Greenlund, Kurt J;Daily Kirley, Pam;Alden, Nisha B;Yousey-Hindes, Kimberly;Anderson, Evan J;Ryan, Patricia A;Kim, Sue;Lynfield, Ruth;Torres, Salina M;Barney, Grant R;Bennett, Nancy M;Sutton, Melissa;Talbot, H Keipp;Hill, Mary;Hall, Aron J;Fry, Alicia M;Garg,...
10.1093/cid/ciaa1419
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Risk Factors for COVID-19-associated hospitalization: COVID-19-Associated Hospitalization Surveillance Network and Behavioral Risk Factor Surveillance System. [Abstract]: BACKGROUND: Data on risk factors for COVID-19-associated hospitalization are needed to guide prevention efforts and clinical care. We sought...
32,376,588
Nan Fang Yi Ke Da Xue Xue Bao
[Supporting the battle against COVID-19 in E'zhou, Hubei Province: the experience of Guizhou medical team].
To suppress the rapid spread of coronavirus disease 2019 (COVID-19) in Hubei province, a medical rescue team consisting of 860 members was sent to E'zhou, one of the hard-hit cities in east Hubei. A total of 414 of the team members, whose core members were from Guizhou Medical University and its Affiliated Hospital, to...
covid-19;hospital staffing;medical rescue;trans-regional
Journal Article
Zhang, Tao;Ran, Limei;Li, Kun;Liu, Jian;Chen, Li;Lu, Jinsong;Liang, Guiyou;Zuo, Shi
10.12122/j.issn.1673-4254.2020.03.12
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [Supporting the battle against COVID-19 in E'zhou, Hubei Province: the experience of Guizhou medical team]. [Abstract]: To suppress the rapid spread of coronavirus disease 2019 (COVID-19) in Hubei province, a medical rescue team consisting of 860 members was sent to E'zhou, one of the hard-hit cities in east H...
32,578,790
Rev Assoc Med Bras (1992)
Beyond ventilatory support: challenges in general practice and in the treatment of critically Ill children and adolescents with SARS-CoV-2 infection.
Severe acute respiratory syndrome coronavirus 2 (Sars-CoV-2 infection) is a new challenge for all countries, and children are predisposed to acquire this disease. Some studies have demonstrated more severe diseases in adults, but critically ill pediatric patients have been described in all ages. Pulmonary involvement i...
Journal Article;Review
Ferranti, Juliana Ferreira;Rodriguez, Isadora Souza;Motta, Emiliana;Johnston, Cintia;Carvalho, Werther Brunow de B;Delgado, Artur Figueiredo
10.1590/1806-9282.66.4.521
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Beyond ventilatory support: challenges in general practice and in the treatment of critically Ill children and adolescents with SARS-CoV-2 infection. [Abstract]: Severe acute respiratory syndrome coronavirus 2 (Sars-CoV-2 infection) is a new challenge for all countries, and children are predisposed to acquire ...
32,911,986
J Investig Med High Impact Case Rep
A Case of Extracorporeal Membrane Oxygenation as a Salvage Therapy for COVID-19-Associated Severe Acute Respiratory Distress Syndrome: Mounting Evidence.
Coronavirus disease 2019 (COVID-19) caused by a novel human coronavirus has led to a tsunami of viral illness across the globe, originating from Wuhan, China. Although the value and effectiveness of extracorporeal membrane oxygenation (ECMO) in severe respiratory illness from COVID-19 remains unclear at this time, ther...
ards;covid-19;ecmo;acute respiratory distress syndrome;extracorporeal membrane oxygenation
Case Reports;Journal Article
Rajdev, Kartikeya;Farr, Lyndie A;Saeed, Muhammad Ahsan;Hooten, Rorak;Baus, Joseph;Boer, Brian
10.1177/2324709620957778
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: A Case of Extracorporeal Membrane Oxygenation as a Salvage Therapy for COVID-19-Associated Severe Acute Respiratory Distress Syndrome: Mounting Evidence. [Abstract]: Coronavirus disease 2019 (COVID-19) caused by a novel human coronavirus has led to a tsunami of viral illness across the globe, originating from ...
32,717,182
Immunity
Lessons for COVID-19 Immunity from Other Coronavirus Infections.
A key goal to controlling coronavirus disease 2019 (COVID-19) is developing an effective vaccine. Development of a vaccine requires knowledge of what constitutes a protective immune response and also features that might be pathogenic. Protective and pathogenic aspects of the response to severe acute respiratory syndrom...
Journal Article;Research Support, N.I.H., Extramural;Review
Sariol, Alan;Perlman, Stanley
10.1016/j.immuni.2020.07.005
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Lessons for COVID-19 Immunity from Other Coronavirus Infections. [Abstract]: A key goal to controlling coronavirus disease 2019 (COVID-19) is developing an effective vaccine. Development of a vaccine requires knowledge of what constitutes a protective immune response and also features that might be pathogenic....
33,006,442
J Clin Hypertens (Greenwich)
Influence of blood pressure control and application of renin-angiotensin-aldosterone system inhibitors on the outcomes in COVID-19 patients with hypertension.
Hypertension is proved to be associated with severity and mortality in coronavirus disease 2019 (COVID-19). However, little is known about the effects of pre-admission and/or in-hospital antihypertension treatments on clinical outcomes. Thus, this study aimed to investigate the association between in-hospital blood pre...
covid-19;raas inhibitors;antihypertensive medicine;blood pressure;clinical outcomes;hypertension
Journal Article
Chen, Renzheng;Yang, Jie;Gao, Xubin;Ding, Xiaohan;Yang, Yuanqi;Shen, Yang;He, Chunyan;Xiang, Hedong;Ke, Jingbin;Yuan, Fangzhengyuan;Cheng, Ran;Lv, Hailin;Li, Ping;Zhang, Limin;Liu, Chuan;Tan, Hu;Huang, Lan
10.1111/jch.14038
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Influence of blood pressure control and application of renin-angiotensin-aldosterone system inhibitors on the outcomes in COVID-19 patients with hypertension. [Abstract]: Hypertension is proved to be associated with severity and mortality in coronavirus disease 2019 (COVID-19). However, little is known about t...
32,936,693
Am J Mens Health
Men and COVID-19: A Pathophysiologic Review.
Coronaviruses are single-stranded ribonucleic acid viruses that can cause illnesses in humans ranging from the common cold to severe respiratory disease and even death.In March 2020, the World Health Organization declared the 2019 novel coronavirus disease (COVID-19) caused by the severe acute respiratory syndrome coro...
covid-19;men;sar-cov-2;coronavirus;crisis;pandemic;pathology;public health
Comparative Study;Journal Article;Review
Lipsky, Martin S;Hung, Man
10.1177/1557988320954021
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Men and COVID-19: A Pathophysiologic Review. [Abstract]: Coronaviruses are single-stranded ribonucleic acid viruses that can cause illnesses in humans ranging from the common cold to severe respiratory disease and even death.In March 2020, the World Health Organization declared the 2019 novel coronavirus disea...
32,810,737
Redox Biol
The cholesterol metabolite 27-hydroxycholesterol inhibits SARS-CoV-2 and is markedly decreased in COVID-19 patients.
There is an urgent need to identify antivirals against the coronavirus SARS-CoV-2 in the current COVID-19 pandemic and to contain future similar emergencies early on. Specific side-chain cholesterol oxidation products of the oxysterols family have been shown to inhibit a large variety of both enveloped and non-envelope...
27-hydroxycholesterol;covid-19;cholesterol;coronavirus;hcov-oc43;oxysterols;sars-cov-2
Journal Article;Research Support, Non-U.S. Gov't
Marcello, Alessandro;Civra, Andrea;Milan Bonotto, Rafaela;Nascimento Alves, Lais;Rajasekharan, Sreejith;Giacobone, Chiara;Caccia, Claudio;Cavalli, Roberta;Adami, Marco;Brambilla, Paolo;Lembo, David;Poli, Giuseppe;Leoni, Valerio
10.1016/j.redox.2020.101682
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: The cholesterol metabolite 27-hydroxycholesterol inhibits SARS-CoV-2 and is markedly decreased in COVID-19 patients. [Abstract]: There is an urgent need to identify antivirals against the coronavirus SARS-CoV-2 in the current COVID-19 pandemic and to contain future similar emergencies early on. Specific side-c...
32,733,706
Radiol Res Pract
Computed Tomography (CT) Imaging Features of Patients with COVID-19: Systematic Review and Meta-Analysis.
Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly contagious disease, and its first outbreak was reported in Wuhan, China. A coronavirus disease (COVID-19) causes severe respiratory distress (ARDS). Due to the primary involvement of the respiratory system, chest CT is strongly recom...
Journal Article;Review
Awulachew, Ephrem;Diriba, Kuma;Anja, Asrat;Getu, Eyob;Belayneh, Firehiwot
10.1155/2020/1023506
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Computed Tomography (CT) Imaging Features of Patients with COVID-19: Systematic Review and Meta-Analysis. [Abstract]: Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly contagious disease, and its first outbreak was reported in Wuhan, China. A coronavirus disease (COVID-19) ...
32,883,088
Clin Appl Thromb Hemost
Methodological Issues and Controversies in COVID-19 Coagulopathy: A Tale of Two Storms.
Venous thromboembolism, occlusion of dialysis catheters, circuit thrombosis in ECMO devices, all in the face of prophylactic and sometimes even therapeutic anti-coagulation, are frequent features of COVID-19 coagulopathy. The trials available to guide clinicians are methodologically limited. There are several unresolve...
Journal Article;Review
Berkman, Samuel A;Tapson, Victor F
10.1177/1076029620945398
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Methodological Issues and Controversies in COVID-19 Coagulopathy: A Tale of Two Storms. [Abstract]: Venous thromboembolism, occlusion of dialysis catheters, circuit thrombosis in ECMO devices, all in the face of prophylactic and sometimes even therapeutic anti-coagulation, are frequent features of COVID-19 coa...
33,023,417
J Biomol Struct Dyn
In silico exploration of small-molecule alpha-helix mimetics as inhibitors of SARS-COV-2 attachment to ACE2.
The novel coronavirus, SARS-CoV-2, has infected more than 10 million people and caused more than 502,539 deaths worldwide as of June 2020. The explosive spread of the virus and the rapid increase in the number of cases require the immediate development of effective therapies and vaccines as well as accurate diagnosis t...
ace2;covid-19;coronavirus;md simulation;sars-cov-2;spike;treatment;virtual screening;alpha-helix mimetics
Journal Article
Hakmi, Mohammed;Bouricha, E L Mehdi;Akachar, Jihane;Lmimouni, Badreddine;El Harti, Jaouad;Belyamani, Lahcen;Ibrahimi, Azeddine
10.1080/07391102.2020.1830175
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: In silico exploration of small-molecule alpha-helix mimetics as inhibitors of SARS-COV-2 attachment to ACE2. [Abstract]: The novel coronavirus, SARS-CoV-2, has infected more than 10 million people and caused more than 502,539 deaths worldwide as of June 2020. The explosive spread of the virus and the rapid inc...
33,007,976
Int J Environ Res Public Health
Hospital and Population-Based Evidence for COVID-19 Early Circulation in the East of France.
BACKGROUND: Understanding SARS-CoV-2 dynamics and transmission is a serious issue. Its propagation needs to be modeled and controlled. The Alsace region in the East of France has been among the first French COVID-19 clusters in 2020. METHODS: We confront evidence from three independent and retrospective sources: a popu...
covid-19;sars-cov-2;emerging infectious disease;epidemic surveillance;epidemic threshold
Journal Article
Gerbaud, Laurent;Guiguet-Auclair, Candy;Breysse, Franck;Odoul, Josephine;Ouchchane, Lemlih;Peterschmitt, Jonathan;Dezfouli-Desfer, Camille;Breton, Vincent
10.3390/ijerph17197175
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Hospital and Population-Based Evidence for COVID-19 Early Circulation in the East of France. [Abstract]: BACKGROUND: Understanding SARS-CoV-2 dynamics and transmission is a serious issue. Its propagation needs to be modeled and controlled. The Alsace region in the East of France has been among the first French...
32,699,768
Int J Spine Surg
Remote Virtual Spinal Evaluation in the Era of COVID-19.
Background: With the COVID-19 pandemic disrupting many facets of our society, physicians and patients have begun using telemedicine as a platform for the delivery of health care. One of the challenges in implementing telemedicine for the spine care provider is completing a comprehensive spinal examination. Currently, t...
motor examination;neurologic examination;neurosurgery;orthopedics;spine examination;spine surgery;telemedicine;virtual clinic;virtual spine evaluation
Journal Article
Yoon, Jang W;Welch, Rachel L;Alamin, Todd;Lavelle, William F;Cheng, Ivan;Perez-Cruet, Mick;Fielding, Louis C;Sasso, Rick C;Linovitz, R J;Kim, Kee D;Welch, William C
10.14444/7057
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Remote Virtual Spinal Evaluation in the Era of COVID-19. [Abstract]: Background: With the COVID-19 pandemic disrupting many facets of our society, physicians and patients have begun using telemedicine as a platform for the delivery of health care. One of the challenges in implementing telemedicine for the spin...