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32,403,946
Future Oncol
Coronavirus disease-2019 in cancer patients. A report of the first 25 cancer patients in a western country (Italy).
Background: We describe cancer patients with coronavirus disease-2019 (COVID-19) infection treated at the Piacenza's general hospital (north Italy). Materials & methods: 25 cancer patients infected by COVID-19 admitted at the Piacenza's general hospital from 21 February to 18 March 2020. Outcome from the infection were...
cancer patients and covid-19;cobicistat;darunavir;hydroxychloroquine;infection and cancer;lopinavir;oncology and coronavirus;ritonavir
Journal Article
Stroppa, Elisa Maria;Toscani, Ilaria;Citterio, Chiara;Anselmi, Elisa;Zaffignani, Elena;Codeluppi, Mauro;Cavanna, Luigi
10.2217/fon-2020-0369
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Coronavirus disease-2019 in cancer patients. A report of the first 25 cancer patients in a western country (Italy). [Abstract]: Background: We describe cancer patients with coronavirus disease-2019 (COVID-19) infection treated at the Piacenza's general hospital (north Italy). Materials & methods: 25 cancer pat...
32,700,580
J Drug Target
Pharmacotherapy in COVID-19 patients: a review of ACE2-raising drugs and their clinical safety.
The COVID-19 pandemic is caused by the severe acute-respiratory-syndrome-coronavirus-2 that uses ACE2 as its receptor. Drugs that raise serum/tissue ACE2 levels include ACE inhibitors (ACEIs) and angiotensin-II receptor blockers (ARBs) that are commonly used in patients with hypertension, cardiovascular disease and/or ...
ace inhibitors;ace2;ang-(1-7);covid-19;dpp-4 inhibitors;glp-1 agonists;mineralocorticoid receptor inhibitors;raas;angiotensin receptor blockers;statins
Journal Article;Review
Akhtar, Saghir;Benter, Ibrahim F;Danjuma, Mohammed I;Doi, Suhail A R;Hasan, Syed S;Habib, Abdella M
10.1080/1061186X.2020.1797754
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Pharmacotherapy in COVID-19 patients: a review of ACE2-raising drugs and their clinical safety. [Abstract]: The COVID-19 pandemic is caused by the severe acute-respiratory-syndrome-coronavirus-2 that uses ACE2 as its receptor. Drugs that raise serum/tissue ACE2 levels include ACE inhibitors (ACEIs) and angiote...
32,510,155
Eur J Cardiothorac Surg
Valve-in-valve transcatheter aortic valve replacement in a young patient with a suspected COVID-19 infection: a surgical dilemma in the era of the COVID-19 pandemic.
We report on a case of a 57-year-old male patient, who underwent full root replacement in 2005 and now presented with high grade aortic insufficiency. On admission, the patient underwent a computed tomography scan which demonstrated interstitial infiltration in the left lung, highly suspicious for a COVID-19 infection ...
covid-19;tavi;valve in valve
Case Reports;Journal Article
Bauernschmitt, Robert;Gabriel, Philip;Gottardi, Roman;Sodian, Ralf
10.1093/ejcts/ezaa193
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Valve-in-valve transcatheter aortic valve replacement in a young patient with a suspected COVID-19 infection: a surgical dilemma in the era of the COVID-19 pandemic. [Abstract]: We report on a case of a 57-year-old male patient, who underwent full root replacement in 2005 and now presented with high grade aort...
32,577,902
Eur Arch Otorhinolaryngol
Olfactory and gustatory abnormalities in COVID-19 cases.
PURPOSE: At the time of writing, there is a pandemic affecting virtually every country on Earth. There is considerable discussion amongst clinicians as well as lay people about anosmia and ageusia in COVID-19 sufferers. We aimed to report the results from comprehensive olfactory and gustatory testing in a series of hos...
covid-19;smell;smell test;taste;virus infection
Journal Article
Altin, Fazilet;Cingi, Cemal;Uzun, Tankut;Bal, Cengiz
10.1007/s00405-020-06155-9
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Olfactory and gustatory abnormalities in COVID-19 cases. [Abstract]: PURPOSE: At the time of writing, there is a pandemic affecting virtually every country on Earth. There is considerable discussion amongst clinicians as well as lay people about anosmia and ageusia in COVID-19 sufferers. We aimed to report the...
32,401,228
J Perinat Med
Are Covid-19-positive mothers dangerous for their term and well newborn babies? Is there an answer?
Background The pandemic caused by the new coronavirus SARS-CoV-2 (Covid-19) is quite a challenging experience for the world. At the moment of birth, the fetus is prepared to face the challenge of labor and the exposure to the outside world, meaning that labor and birth represent the first extrauterine major exposure to...
covid-19;sars-cov-2;international instructions;neonate;outbreak;perinatal period;pregnancy
Journal Article
Stanojevic, Milan
10.1515/jpm-2020-0186
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Are Covid-19-positive mothers dangerous for their term and well newborn babies? Is there an answer? [Abstract]: Background The pandemic caused by the new coronavirus SARS-CoV-2 (Covid-19) is quite a challenging experience for the world. At the moment of birth, the fetus is prepared to face the challenge of lab...
33,014,801
Front Oncol
Expert Consensus for Treating Cancer Patients During the Pandemic of SARS-CoV-2.
The sudden pandemic of SARS-Cov-2 (also known as novel coronavirus disease 2019, COVID-19) poses a severe threat to hundreds of millions of lives in the world. The complete cure of the virus largely relies on the immune system, which becomes particularly a challenge for the cancer subjects, whose immunity is generally ...
covid-19;sars-cov-2;cancer;consensus;coronavirus;immunotherapy;treatment
Journal Article
Dong, Shuang;Luo, Chenggang;Hu, Xuebo;Zhang, Jing;Cai, Qian;Qian, Yu;Ran, Fengming;Ou, Wuling;Wang, Jun;Huang, Qing;Ren, Tianhua;Han, Guang;Zhang, Feng;Wei, Wei;Liang, Xinjun;Xu, Huiting;Wang, Sheng;Shi, Lulu;Wei, Shaozhong;Hu, Sheng
10.3389/fonc.2020.01555
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Expert Consensus for Treating Cancer Patients During the Pandemic of SARS-CoV-2. [Abstract]: The sudden pandemic of SARS-Cov-2 (also known as novel coronavirus disease 2019, COVID-19) poses a severe threat to hundreds of millions of lives in the world. The complete cure of the virus largely relies on the immun...
32,890,666
J Am Coll Cardiol
Echocardiographic Findings in Pediatric Multisystem Inflammatory Syndrome Associated With COVID-19 in the United States.
BACKGROUND: Centers from Europe and United States have reported an exceedingly high number of children with a severe inflammatory syndrome in the setting of coronavirus disease 2019, which has been termed multisystem inflammatory syndrome in children (MIS-C). OBJECTIVES: This study aimed to analyze echocardiographic ma...
covid-19;coronary artery abnormality;deformation;echocardiography;multisystem inflammatory syndrome in children (mis-c);myocarditis
Journal Article
Matsubara, Daisuke;Kauffman, Hunter L;Wang, Yan;Calderon-Anyosa, Renzo;Nadaraj, Sumekala;Elias, Matthew D;White, Travus J;Torowicz, Deborah L;Yubbu, Putri;Giglia, Therese M;Hogarty, Alexa N;Rossano, Joseph W;Quartermain, Michael D;Banerjee, Anirban
10.1016/j.jacc.2020.08.056
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Echocardiographic Findings in Pediatric Multisystem Inflammatory Syndrome Associated With COVID-19 in the United States. [Abstract]: BACKGROUND: Centers from Europe and United States have reported an exceedingly high number of children with a severe inflammatory syndrome in the setting of coronavirus disease 2...
32,819,897
AJNR Am J Neuroradiol
Regional Mechanical Thrombectomy Imaging Protocol in Patients Presenting with Acute Ischemic Stroke during the COVID-19 Pandemic.
BACKGROUND AND PURPOSE: Chest CT is a rapid, useful additional screening tool for coronavirus disease 2019 (COVID-19) in emergent procedures. We describe the feasibility and interim outcome of implementing a modified imaging algorithm for COVID-19 risk stratification across a regional network of primary stroke centers ...
Journal Article;Research Support, Non-U.S. Gov't
Dhillon, P S;Pointon, K;Lenthall, R;Nair, S;Subramanian, G;McConachie, N;Izzath, W
10.3174/ajnr.A6754
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Regional Mechanical Thrombectomy Imaging Protocol in Patients Presenting with Acute Ischemic Stroke during the COVID-19 Pandemic. [Abstract]: BACKGROUND AND PURPOSE: Chest CT is a rapid, useful additional screening tool for coronavirus disease 2019 (COVID-19) in emergent procedures. We describe the feasibility...
32,178,768
Lancet
First known person-to-person transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the USA.
BACKGROUND: Coronavirus disease 2019 (COVID-19) is a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first detected in China in December, 2019. In January, 2020, state, local, and federal public health agencies investigated the first case of COVID-19 in Illinois, USA. METHODS: Patients w...
Case Reports;Journal Article
Ghinai, Isaac;McPherson, Tristan D;Hunter, Jennifer C;Kirking, Hannah L;Christiansen, Demian;Joshi, Kiran;Rubin, Rachel;Morales-Estrada, Shirley;Black, Stephanie R;Pacilli, Massimo;Fricchione, Marielle J;Chugh, Rashmi K;Walblay, Kelly A;Ahmed, N Seema;Stoecker, William C;Hasan, Nausheen F;Burdsall, Deborah P;Reese, Hea...
10.1016/S0140-6736(20)30607-3
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: First known person-to-person transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the USA. [Abstract]: BACKGROUND: Coronavirus disease 2019 (COVID-19) is a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first detected in China in December, 2019. In Ja...
33,061,486
Infect Drug Resist
Saliva as an Alternative Specimen for Molecular COVID-19 Testing in Community Settings and Population-Based Screening.
Purpose: With the easing of restriction measures, repeated community-based sampling for tracking new COVID-19 infections is anticipated for the next 6 to 12 months. A non-invasive, self-collected specimen like saliva will be useful for such public health surveillance. Investigations on the use of saliva for SARS-CoV-2 ...
sars-cov-2;molecular test;nasopharyngeal swab;population-based screening;saliva
Journal Article
Senok, Abiola;Alsuwaidi, Hanan;Atrah, Yusrah;Al Ayedi, Ola;Al Zahid, Janan;Han, Aaron;Al Marzooqi, Asma;Al Heialy, Saba;Altrabulsi, Basel;AbdelWareth, Laila;Idaghdour, Youssef;Ali, Raghib;Loney, Tom;Alsheikh-Ali, Alawi
10.2147/IDR.S275152
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Saliva as an Alternative Specimen for Molecular COVID-19 Testing in Community Settings and Population-Based Screening. [Abstract]: Purpose: With the easing of restriction measures, repeated community-based sampling for tracking new COVID-19 infections is anticipated for the next 6 to 12 months. A non-invasive,...
32,956,730
J Infect
Excess mortality due to COVID-19 in Germany.
OBJECTIVES: The first wave of the SARS-CoV-2 pandemic in Germany lasted from week 10 to 23 in 2020. The aim is to provide estimates of excess mortality in Germany during this time. METHODS: We analyzed age-specific numbers of deaths per week from 2016 to week 26 in 2020. We used weekly mean numbers of deaths of 2016-20...
covid-19;corona virus;germany;mortality;pandemic
Journal Article
Stang, Andreas;Standl, Fabian;Kowall, Bernd;Brune, Bastian;Bottcher, Juliane;Brinkmann, Marcus;Dittmer, Ulf;Jockel, Karl-Heinz
10.1016/j.jinf.2020.09.012
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Excess mortality due to COVID-19 in Germany. [Abstract]: OBJECTIVES: The first wave of the SARS-CoV-2 pandemic in Germany lasted from week 10 to 23 in 2020. The aim is to provide estimates of excess mortality in Germany during this time. METHODS: We analyzed age-specific numbers of deaths per week from 2016 to...
33,037,946
Emerg Radiol
Dynamic evaluation of lung involvement during coronavirus disease-2019 (COVID-19) with quantitative lung CT.
PURPOSE: To identify and quantify lung changes associated with coronavirus disease-2019 (COVID-19) with quantitative lung CT during the disease. METHODS: This retrospective study reviewed COVID-19 patients who underwent multiple chest CT scans during their disease course. Quantitative lung CT was used to determine the ...
artificial intelligence;coronavirus;lung;pneumonia;tomography;x-ray;viral
Journal Article
Ma, Chun;Wang, Xiao-Ling;Xie, Dong-Mei;Li, Yu-Dan;Zheng, Yong-Ji;Zhang, Hai-Bing;Ming, Bing
10.1007/s10140-020-01856-4
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Dynamic evaluation of lung involvement during coronavirus disease-2019 (COVID-19) with quantitative lung CT. [Abstract]: PURPOSE: To identify and quantify lung changes associated with coronavirus disease-2019 (COVID-19) with quantitative lung CT during the disease. METHODS: This retrospective study reviewed CO...
33,031,744
Cell
A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice.
The SARS-CoV-2 pandemic has caused extreme human suffering and economic harm. We generated and characterized a new mouse-adapted SARS-CoV-2 virus that captures multiple aspects of severe COVID-19 disease in standard laboratory mice. This SARS-CoV-2 model exhibits the spectrum of morbidity and mortality of COVID-19 dise...
covid-19;sars-cov-2;acute lung injury;acute respiratory distress syndrome;animal models;interferon;mouse-adaptation;vaccines
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Leist, Sarah R;Dinnon, Kenneth H 3rd;Schafer, Alexandra;Tse, Longping V;Okuda, Kenichi;Hou, Yixuan J;West, Ande;Edwards, Caitlin E;Sanders, Wes;Fritch, Ethan J;Gully, Kendra L;Scobey, Trevor;Brown, Ariane J;Sheahan, Timothy P;Moorman, Nathaniel J;Boucher, Richard C;Gralinski, Lisa E;Montgomery, Stephanie A;Baric, Ralph...
10.1016/j.cell.2020.09.050
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice. [Abstract]: The SARS-CoV-2 pandemic has caused extreme human suffering and economic harm. We generated and characterized a new mouse-adapted SARS-CoV-2 virus that captures multiple aspects of severe COVID-19 disease...
32,834,402
Int Stat Rev
A Review of Multi-Compartment Infectious Disease Models.
Multi-compartment models have been playing a central role in modelling infectious disease dynamics since the early 20th century. They are a class of mathematical models widely used for describing the mechanism of an evolving epidemic. Integrated with certain sampling schemes, such mechanistic models can be applied to a...
covid-19;markov chain monte carlo;antibody;cellular automaton;risk prediction;spatio-temporal model;state-space model
Journal Article
Tang, Lu;Zhou, Yiwang;Wang, Lili;Purkayastha, Soumik;Zhang, Leyao;He, Jie;Wang, Fei;Song, Peter X-K
10.1111/insr.12402
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: A Review of Multi-Compartment Infectious Disease Models. [Abstract]: Multi-compartment models have been playing a central role in modelling infectious disease dynamics since the early 20th century. They are a class of mathematical models widely used for describing the mechanism of an evolving epidemic. Integra...
32,448,041
J Biomol Struct Dyn
Covid-19 induced superimposed bacterial infection.
Viral respiratory infections are very common and they are frequently eliminated from the body without any detrimental consequences. Secondary serious bacterial infection has been an apprehension expressed by health care providers, and this fear has been exacerbated in the era of Covid-19. Several published studies have...
covid-19;pathogenesis;secondary bacterial infection;studies
Journal Article
Hendaus, Mohamed A;Jomha, Fatima A
10.1080/07391102.2020.1772110
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Covid-19 induced superimposed bacterial infection. [Abstract]: Viral respiratory infections are very common and they are frequently eliminated from the body without any detrimental consequences. Secondary serious bacterial infection has been an apprehension expressed by health care providers, and this fear has...
32,387,230
Res Social Adm Pharm
When fear and misinformation go viral: Pharmacists' role in deterring medication misinformation during the 'infodemic' surrounding COVID-19.
The world has faced an unprecedented challenge when coronavirus (COVID-19) emerged as a pandemic. Millions of people have contracted the virus and a significant number of them lost their lives, resulting in a tremendous social and economic shock across the globe. Amid the growing burden of the pandemic, there are paral...
covid-19;coronavirus;misinformation;pandemics;pharmacists
Journal Article
Erku, Daniel A;Belachew, Sewunet A;Abrha, Solomon;Sinnollareddy, Mahipal;Thomas, Jackson;Steadman, Kathryn J;Tesfaye, Wubshet H
10.1016/j.sapharm.2020.04.032
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: When fear and misinformation go viral: Pharmacists' role in deterring medication misinformation during the 'infodemic' surrounding COVID-19. [Abstract]: The world has faced an unprecedented challenge when coronavirus (COVID-19) emerged as a pandemic. Millions of people have contracted the virus and a significa...
33,015,604
Biosaf Health
Facing the 2020 Pandemic: What does Cyberbiosecurity want us to know to safeguard the future?
As the entire world is under the grip of the Coronavirus diseases 2019 (COVID-19), and as many are eagerly trying to explain the origins of the virus and cause of the pandemic, it is imperative to place more attention on related potential biosafety risks. Biology and biotechnology have changed dramatically during the l...
biolabs of the future;convergence;cyberbiosecurity;laboratory safety;protective measures;risk assessment
Journal Article;Review
Mueller, Siguna
10.1016/j.bsheal.2020.09.007
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Facing the 2020 Pandemic: What does Cyberbiosecurity want us to know to safeguard the future? [Abstract]: As the entire world is under the grip of the Coronavirus diseases 2019 (COVID-19), and as many are eagerly trying to explain the origins of the virus and cause of the pandemic, it is imperative to place mo...
32,631,702
Surgeon
A protocol for wide awake local anaesthetic no tourniquet (WALANT) hand surgery in the context of the coronavirus disease 2019 (COVID-19) pandemic.
There are new and unique challenges to emergency surgery service provision posed by the Coronavirus disease 2019 global pandemic. It is in the best interests of patients for care providers to streamline services where possible to maximise the number of cases that can be performed by limited surgical and anaesthetic tea...
covid-19;hand surgery;service provision;walant
Journal Article
Hobday, Dorian;Welman, Ted;O'Neill, Niamh;Pahal, Gurjinderpal Singh
10.1016/j.surge.2020.06.015
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: A protocol for wide awake local anaesthetic no tourniquet (WALANT) hand surgery in the context of the coronavirus disease 2019 (COVID-19) pandemic. [Abstract]: There are new and unique challenges to emergency surgery service provision posed by the Coronavirus disease 2019 global pandemic. It is in the best int...
32,535,732
Pharmaceut Med
IL-6 Inhibitors in the Treatment of Serious COVID-19: A Promising Therapy?
At present, there are no proven agents for treatment of coronavirus disease (COVID-19). The available evidence has not allowed guidelines to clearly recommend any drugs outside the context of clinical trials. The novel coronavirus SARS-CoV-2 that causes COVID-19 invokes a hyperinflammatory state driven by multiple cell...
Journal Article
Atal, Shubham;Fatima, Zeenat
10.1007/s40290-020-00342-z
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: IL-6 Inhibitors in the Treatment of Serious COVID-19: A Promising Therapy? [Abstract]: At present, there are no proven agents for treatment of coronavirus disease (COVID-19). The available evidence has not allowed guidelines to clearly recommend any drugs outside the context of clinical trials. The novel coron...
32,390,367
Yonsei Med J
Clinical Features and Outcomes of 98 Patients Hospitalized with SARS-CoV-2 Infection in Daegu, South Korea: A Brief Descriptive Study.
Although some information on the epidemiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and a few selected cases has been reported, data on the clinical characteristics and outcomes of patients hospitalized therewith in South Korea are lacking. We conducted a retrospective single-center study of 9...
covid-19;coronavirus;korea;sars-cov-2;clinical characteristics
Journal Article
Hong, Kyung Soo;Lee, Kwan Ho;Chung, Jin Hong;Shin, Kyeong Cheol;Choi, Eun Young;Jin, Hyun Jung;Jang, Jong Geol;Lee, Wonhwa;Ahn, June Hong
10.3349/ymj.2020.61.5.431
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical Features and Outcomes of 98 Patients Hospitalized with SARS-CoV-2 Infection in Daegu, South Korea: A Brief Descriptive Study. [Abstract]: Although some information on the epidemiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and a few selected cases has been reported, data on th...
32,307,265
Eur Ann Otorhinolaryngol Head Neck Dis
French consensus regarding precautions during tracheostomy and post-tracheostomy care in the context of COVID-19 pandemic.
Tracheostomy post-tracheostomy care are regarded as at high risk for contamination of health care professionals with the new coronavirus (SARS-CoV-2). Considering the rapid spread of the infection, all patients in France must be considered as potentially infected by the virus. Nevertheless, patients without clinical or...
covid-19;care;pandemic;percutaneous;sars-cov-2;tracheostomy
Practice Guideline
Schultz, P;Morvan, J-B;Fakhry, N;Moriniere, S;Vergez, S;Lacroix, C;Bartier, S;Barry, B;Babin, E;Couloigner, V;Atallah, I
10.1016/j.anorl.2020.04.006
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: French consensus regarding precautions during tracheostomy and post-tracheostomy care in the context of COVID-19 pandemic. [Abstract]: Tracheostomy post-tracheostomy care are regarded as at high risk for contamination of health care professionals with the new coronavirus (SARS-CoV-2). Considering the rapid spr...
32,404,431
Pediatrics
A Case Series of the 2019 Novel Coronavirus (SARS-CoV-2) in 3 Febrile Infants in New York.
We describe 3 febrile infants <2 months of age admitted to a large tertiary care children's hospital in New York and subsequently found to be infected with severe acute respiratory syndrome coronavirus 2. All 3 patients presented with fever, feeding difficulty, lymphopenia, and thrombocytosis on laboratory evaluation. ...
Case Reports;Journal Article
Feld, Lance;Belfer, Joshua;Kabra, Rashi;Goenka, Pratichi;Rai, Shipra;Moriarty, Shannon;Barone, Stephen
10.1542/peds.2020-1056
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: A Case Series of the 2019 Novel Coronavirus (SARS-CoV-2) in 3 Febrile Infants in New York. [Abstract]: We describe 3 febrile infants <2 months of age admitted to a large tertiary care children's hospital in New York and subsequently found to be infected with severe acute respiratory syndrome coronavirus 2. All...
32,134,381
Emerg Infect Dis
Lack of Vertical Transmission of Severe Acute Respiratory Syndrome Coronavirus 2, China.
A woman with coronavirus disease in her 35th week of pregnancy delivered an infant by cesarean section in a negative-pressure operating room. The infant was negative for severe acute respiratory coronavirus 2. This case suggests that mother-to-child transmission is unlikely for this virus.
2019 novel coronavirus disease;covid-19;china;sars-cov-2;severe acute respiratory syndrome coronavirus 2;coronaviruses;pregnancy;respiratory infections;vertical transmission;viruses
Case Reports;Journal Article
Li, Yang;Zhao, Ruihong;Zheng, Shufa;Chen, Xu;Wang, Jinxi;Sheng, Xiaoli;Zhou, Jianying;Cai, Hongliu;Fang, Qiang;Yu, Fei;Fan, Jian;Xu, Kaijin;Chen, Yu;Sheng, Jifang
10.3201/eid2606.200287
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Lack of Vertical Transmission of Severe Acute Respiratory Syndrome Coronavirus 2, China. [Abstract]: A woman with coronavirus disease in her 35th week of pregnancy delivered an infant by cesarean section in a negative-pressure operating room. The infant was negative for severe acute respiratory coronavirus 2. ...
32,821,883
ACS Pharmacol Transl Sci
SARS-CoV-2 Receptor ACE2 Is Enriched in a Subpopulation of Mouse Tongue Epithelial Cells in Nongustatory Papillae but Not in Taste Buds or Embryonic Oral Epithelium.
As a result of the COVID-19 pandemic, evidence revealed that SARS-CoV-2 infection caused taste loss at a rate higher than that of influenza. ACE2, the entry receptor of SARS-CoV-2, has been identified in the oral epithelium; however, it is unclear at what developmental stage ACE2 expression emerges and whether ACE2 is ...
Journal Article
Wang, Zhonghou;Zhou, Jingqi;Marshall, Brett;Rekaya, Romdhane;Ye, Kaixiong;Liu, Hong-Xiang
10.1021/acsptsci.0c00062
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: SARS-CoV-2 Receptor ACE2 Is Enriched in a Subpopulation of Mouse Tongue Epithelial Cells in Nongustatory Papillae but Not in Taste Buds or Embryonic Oral Epithelium. [Abstract]: As a result of the COVID-19 pandemic, evidence revealed that SARS-CoV-2 infection caused taste loss at a rate higher than that of inf...
32,473,151
Clin Biochem
Laboratory abnormalities in children with mild and severe coronavirus disease 2019 (COVID-19): A pooled analysis and review.
Limited data exists to-date on the laboratory findings in children with COVID-19, warranting the conduction of this study, in which we pool the currently available literature data on the laboratory findings seen in children with mild and severe COVID-19. Following an extensive literature search, we identified 24 eligib...
biomarkers;clinical chemistry;inflammation;pediatrics;sars-cov-2
Journal Article;Meta-Analysis;Review
Henry, Brandon Michael;Benoit, Stefanie W;de Oliveira, Maria Helena Santos;Hsieh, Wan Chin;Benoit, Justin;Ballout, Rami A;Plebani, Mario;Lippi, Giuseppe
10.1016/j.clinbiochem.2020.05.012
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Laboratory abnormalities in children with mild and severe coronavirus disease 2019 (COVID-19): A pooled analysis and review. [Abstract]: Limited data exists to-date on the laboratory findings in children with COVID-19, warranting the conduction of this study, in which we pool the currently available literature...
32,486,283
Viruses
Reporter Replicons for Antiviral Drug Discovery against Positive Single-Stranded RNA Viruses.
Single-stranded positive RNA ((+) ssRNA) viruses include several important human pathogens. Some members are responsible for large outbreaks, such as Zika virus, West Nile virus, SARS-CoV, and SARS-CoV-2, while others are endemic, causing an enormous global health burden. Since vaccines or specific treatments are not a...
(+) ssrna viruses;key-words: replicon systems;direct-acting antivirals;drug discovery
Journal Article;Research Support, Non-U.S. Gov't;Review
Fernandes, Rafaela S;Freire, Marjorie C L C;Bueno, Renata V;Godoy, Andre S;Gil, Laura H V G;Oliva, Glaucius
10.3390/v12060598
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Reporter Replicons for Antiviral Drug Discovery against Positive Single-Stranded RNA Viruses. [Abstract]: Single-stranded positive RNA ((+) ssRNA) viruses include several important human pathogens. Some members are responsible for large outbreaks, such as Zika virus, West Nile virus, SARS-CoV, and SARS-CoV-2, ...
32,982,081
Chaos Solitons Fractals
Mathematical modeling, analysis and numerical simulation of the COVID-19 transmission with mitigation of control strategies used in Cameroon.
In this paper, we formulated a general model of COVID-19model transmission using biological features of the disease and control strategies based on the isolation of exposed people, confinement (lock-downs) of the human population, testing people living risks area, wearing of masks and respect of hygienic rules. We prov...
backward;basic reproduction number;extinction;masks;persistence;quarantine;testing
Journal Article
Djaoue, Seraphin;Guilsou Kolaye, Gabriel;Abboubakar, Hamadjam;Abba Ari, Ado Adamou;Damakoa, Irepran
10.1016/j.chaos.2020.110281
[ 0, 0, 1, 0, 1, 0, 0 ]
[Title]: Mathematical modeling, analysis and numerical simulation of the COVID-19 transmission with mitigation of control strategies used in Cameroon. [Abstract]: In this paper, we formulated a general model of COVID-19model transmission using biological features of the disease and control strategies based on the isola...
32,903,363
Front Pharmacol
Corticosteroid Use in the Treatment of COVID-19: A Multicenter Retrospective Study in Hunan, China.
Background: Coronavirus disease 2019 (COVID-19) has developed into a worldwide pandemic. This study aimed to retrospectively describe the use of corticosteroids in treating COVID-19. Methods: For this multicenter retrospective study, medical records from 488 symptomatic COVID-19 patients were reviewed. Patients were di...
covid-19;antibiotic;corticosteroid;treatment;viral shedding
Journal Article
Ma, Yiming;Zeng, Huihui;Zhan, Zijie;Lu, Huanhuan;Zeng, Zihang;He, Chenjie;Liu, Xiangming;Chen, Chen;Qin, Qingwu;He, Jia;Zhou, Zhiguo;Huang, Peng;Jiang, Mingyan;Deng, Dingding;Liao, Xin;Xiang, Zhi;Huang, Xiaoying;Chen, Yan;Chen, Ping
10.3389/fphar.2020.01198
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Corticosteroid Use in the Treatment of COVID-19: A Multicenter Retrospective Study in Hunan, China. [Abstract]: Background: Coronavirus disease 2019 (COVID-19) has developed into a worldwide pandemic. This study aimed to retrospectively describe the use of corticosteroids in treating COVID-19. Methods: For thi...
32,339,304
Pharmacotherapy
Managing COVID-19 in Renal Transplant Recipients: A Review of Recent Literature and Case Supporting Corticosteroid-sparing Immunosuppression.
Novel coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome virus (SARS-CoV-2) has become a global health care crisis. The Centers for Disease Control and Prevention (CDC) lists immunocompromised patients, including those requiring immunosuppression following renal transplantation, as high ris...
covid-19;sars-cov-2;coronavirus;corticosteroid;immunosuppression;renal transplant
Journal Article;Review
Johnson, Kristen M;Belfer, Julie J;Peterson, Gina R;Boelkins, Mark R;Dumkow, Lisa E
10.1002/phar.2410
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Managing COVID-19 in Renal Transplant Recipients: A Review of Recent Literature and Case Supporting Corticosteroid-sparing Immunosuppression. [Abstract]: Novel coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome virus (SARS-CoV-2) has become a global health care crisis. The Centers ...
32,425,642
Int J Infect Dis
Pathways to COVID-19 'community protection'.
To date, no country has reached a natural COVID-19 epidemic peak and observed peaks essentially reflect the effectiveness of 'lockdown' measures. The major challenge is finding a responsible way out of 'lockdown', given that SARS- CoV-2 is now an established global pathogen. Acknowledging limitations in our knowledge r...
covid-19;community protection;controlled infection;herd immunity;sars cov-2
Journal Article
Marais, B J;Sorrell, T C
10.1016/j.ijid.2020.05.058
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Pathways to COVID-19 'community protection'. [Abstract]: To date, no country has reached a natural COVID-19 epidemic peak and observed peaks essentially reflect the effectiveness of 'lockdown' measures. The major challenge is finding a responsible way out of 'lockdown', given that SARS- CoV-2 is now an establi...
32,917,840
Thorax
SARS-CoV-2 seroprevalence and asymptomatic viral carriage in healthcare workers: a cross-sectional study.
OBJECTIVE: To determine the rates of asymptomatic viral carriage and seroprevalence of SARS-CoV-2 antibodies in healthcare workers. DESIGN: A cross-sectional study of asymptomatic healthcare workers undertaken on 24/25 April 2020. SETTING: University Hospitals Birmingham NHS Foundation Trust (UHBFT), UK. PARTICIPANTS: ...
clinical epidemiology;infection control;respiratory infection;viral infection
Journal Article;Research Support, Non-U.S. Gov't
Shields, Adrian;Faustini, Sian E;Perez-Toledo, Marisol;Jossi, Sian;Aldera, Erin;Allen, Joel D;Al-Taei, Saly;Backhouse, Claire;Bosworth, Andrew;Dunbar, Lyndsey A;Ebanks, Daniel;Emmanuel, Beena;Garvey, Mark;Gray, Joanna;Kidd, I Michael;McGinnell, Golaleh;McLoughlin, Dee E;Morley, Gabriella;O'Neill, Joanna;Papakonstantino...
10.1136/thoraxjnl-2020-215414
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: SARS-CoV-2 seroprevalence and asymptomatic viral carriage in healthcare workers: a cross-sectional study. [Abstract]: OBJECTIVE: To determine the rates of asymptomatic viral carriage and seroprevalence of SARS-CoV-2 antibodies in healthcare workers. DESIGN: A cross-sectional study of asymptomatic healthcare wo...
32,809,969
J Clin Invest
Baricitinib restrains the immune dysregulation in patients with severe COVID-19.
BACKGROUNDPatients with coronavirus disease 2019 (COVID-19) develop pneumonia generally associated with lymphopenia and a severe inflammatory response due to uncontrolled cytokine release. These mediators are transcriptionally regulated by the JAK/STAT signaling pathways, which can be disabled by small molecules.METHOD...
covid-19;immunology;innate immunity
Clinical Trial;Journal Article;Multicenter Study;Observational Study
Bronte, Vincenzo;Ugel, Stefano;Tinazzi, Elisa;Vella, Antonio;De Sanctis, Francesco;Cane, Stefania;Batani, Veronica;Trovato, Rosalinda;Fiore, Alessandra;Petrova, Varvara;Hofer, Francesca;Barouni, Roza Maria;Musiu, Chiara;Caligola, Simone;Pinton, Laura;Torroni, Lorena;Polati, Enrico;Donadello, Katia;Friso, Simonetta;Pizz...
10.1172/JCI141772
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Baricitinib restrains the immune dysregulation in patients with severe COVID-19. [Abstract]: BACKGROUNDPatients with coronavirus disease 2019 (COVID-19) develop pneumonia generally associated with lymphopenia and a severe inflammatory response due to uncontrolled cytokine release. These mediators are transcrip...
32,754,119
Front Endocrinol (Lausanne)
Impaired Fasting Glucose and Diabetes Are Related to Higher Risks of Complications and Mortality Among Patients With Coronavirus Disease 2019.
Background: Diabetes correlates with poor prognosis in patients with COVID-19, but very few studies have evaluated whether impaired fasting glucose (IFG) is also a risk factor for the poor outcomes of patients with COVID-19. Here we aimed to examine the associations between IFG and diabetes at admission with risks of c...
covid-19;cohort study;coronavirus;diabetes;hyperglycemia;impaired fasting glucose;severe acute respiratory coronavirus 2 (sars-cov-2)
Journal Article;Multicenter Study;Research Support, Non-U.S. Gov't
Zhang, Jiaoyue;Kong, Wen;Xia, Pengfei;Xu, Ying;Li, Li;Li, Qin;Yang, Li;Wei, Qi;Wang, Hanyu;Li, Huiqing;Zheng, Juan;Sun, Hui;Xia, Wenfang;Liu, Geng;Zhong, Xueyu;Qiu, Kangli;Li, Yan;Wang, Han;Wang, Yuxiu;Song, Xiaoli;Liu, Hua;Xiong, Si;Liu, Yumei;Cui, Zhenhai;Hu, Yu;Chen, Lulu;Pan, An;Zeng, Tianshu
10.3389/fendo.2020.00525
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Impaired Fasting Glucose and Diabetes Are Related to Higher Risks of Complications and Mortality Among Patients With Coronavirus Disease 2019. [Abstract]: Background: Diabetes correlates with poor prognosis in patients with COVID-19, but very few studies have evaluated whether impaired fasting glucose (IFG) is...
32,834,770
Theor Chem Acc
Favipiravir tautomerism: a theoretical insight.
There is no experimental information about the tautomerism of Favipiravir (T-705). Therefore, its tautomeric state was predicted by using density functional theory in gas phase and in solution (toluene, acetonitrile and water). The results have shown that, in neutral state, the enol form is strongly dominating in both ...
avigan;covid-19;density functional calculations;favilavir;favipiravir;t-705;tautomerism
Journal Article
Antonov, Liudmil
10.1007/s00214-020-02656-2
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Favipiravir tautomerism: a theoretical insight. [Abstract]: There is no experimental information about the tautomerism of Favipiravir (T-705). Therefore, its tautomeric state was predicted by using density functional theory in gas phase and in solution (toluene, acetonitrile and water). The results have shown ...
32,833,780
Crit Care Nurs Q
Leading Through the Unknown: A Network Perspective of the COVID-19 Pandemic.
This article provides a road map to swiftly operationalize the structure and process for organizational readiness in response to the COVID-19 pandemic. The pandemic forced network leaders to face an unprecedented public health crisis while navigating circumstances driven by a widely impactful disease with minimal empir...
Journal Article
Coe, Paula F;Graper, Lisa L;Zangerle, Claire M
10.1097/CNQ.0000000000000329
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Leading Through the Unknown: A Network Perspective of the COVID-19 Pandemic. [Abstract]: This article provides a road map to swiftly operationalize the structure and process for organizational readiness in response to the COVID-19 pandemic. The pandemic forced network leaders to face an unprecedented public he...
32,449,851
Can J Surg
Operating during COVID-19: Is there a risk of viral transmission from surgical smoke during surgery?
Summary: The World Health Organization declared a pandemic when coronavirus disease 2019 (COVID-19) started to sweep the globe. Growing concerns for the safety of health care workers was raised when up to 80% of people with COVID-19 showed mild or no symptoms at all. Some surgical procedures will be inevitable during t...
Journal Article;Comment
Vourtzoumis, Phil;Alkhamesi, Nawar;Elnahas, Ahmad;Hawel, Jeffrey E;Schlachta, Christopher
10.1503/cjs.007020
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Operating during COVID-19: Is there a risk of viral transmission from surgical smoke during surgery? [Abstract]: Summary: The World Health Organization declared a pandemic when coronavirus disease 2019 (COVID-19) started to sweep the globe. Growing concerns for the safety of health care workers was raised when...
32,900,400
Disaster Med Public Health Prep
Prediction of the Peak, Effect of Intervention, and Total Infected by COVID-19 in India.
OBJECTIVES: We study the effect of the coronavirus disease 2019 (COVID-19) in India and model the epidemic to guide those involved in formulating policy and building health-care capacity. METHODS: This effect is studied using the Susceptible-Exposed-Infected-Recovered (SEIR) compartmental model. We estimate the infecti...
covid-19;india;seir compartmental model;infection rate;intervention;peak prediction
Journal Article
Shah, Parth Vipul
10.1017/dmp.2020.321
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: Prediction of the Peak, Effect of Intervention, and Total Infected by COVID-19 in India. [Abstract]: OBJECTIVES: We study the effect of the coronavirus disease 2019 (COVID-19) in India and model the epidemic to guide those involved in formulating policy and building health-care capacity. METHODS: This effect i...
32,866,493
J Theor Biol
Predicting the second wave of COVID-19 in Washtenaw County, MI.
The COVID-19 pandemic has highlighted the patchwork nature of disease epidemics, with infection spread dynamics varying wildly across countries and across states within the US. To explore this issue, we study and predict the spread of COVID-19 in Washtenaw County, MI, which is home to University of Michigan and Eastern...
coronavirus;epidemiology;network-based model
Journal Article;Research Support, N.I.H., Extramural;Research Support, U.S. Gov't, Non-P.H.S.
Renardy, Marissa;Eisenberg, Marisa;Kirschner, Denise
10.1016/j.jtbi.2020.110461
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: Predicting the second wave of COVID-19 in Washtenaw County, MI. [Abstract]: The COVID-19 pandemic has highlighted the patchwork nature of disease epidemics, with infection spread dynamics varying wildly across countries and across states within the US. To explore this issue, we study and predict the spread of ...
32,855,527
Hypertens Res
Blood pressure control and adverse outcomes of COVID-19 infection in patients with concomitant hypertension in Wuhan, China.
Hypertension is a common comorbidity in hospitalized patients with COVID-19 infection. This study aimed to estimate the risks of adverse events associated with in-hospital blood pressure (BP) control and the effects of angiotensin II receptor blocker (ARB) prescription in COVID-19 patients with concomitant hypertension...
covid-19;heart failure;hypertension;intensive care unit;mortality
Journal Article;Research Support, Non-U.S. Gov't
Ran, Jinjun;Song, Ying;Zhuang, Zian;Han, Lefei;Zhao, Shi;Cao, Peihua;Geng, Yan;Xu, Lin;Qin, Jing;He, Daihai;Wu, Fengfu;Yang, Lin
10.1038/s41440-020-00541-w
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Blood pressure control and adverse outcomes of COVID-19 infection in patients with concomitant hypertension in Wuhan, China. [Abstract]: Hypertension is a common comorbidity in hospitalized patients with COVID-19 infection. This study aimed to estimate the risks of adverse events associated with in-hospital bl...
33,004,091
Camb Q Healthc Ethics
Return to Status Quo Ante: The Need for Robust and Reversible Pandemic Emergency Measures.
This paper presents a normative analysis of restrictive measures in response to a pandemic emergency. It applies to the context presented by the Corona virus disease 2019 (COVID-19) global outbreak of 2019, as well as to future pandemics. First, a Millian-liberal argument justifies lockdown measures in order to protect...
corona virus;ethics;pandemic response;political legitimacy
Journal Article
Rainey, Stephen;Giubilini, Alberto
10.1017/S096318012000078X
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Return to Status Quo Ante: The Need for Robust and Reversible Pandemic Emergency Measures. [Abstract]: This paper presents a normative analysis of restrictive measures in response to a pandemic emergency. It applies to the context presented by the Corona virus disease 2019 (COVID-19) global outbreak of 2019, a...
32,715,628
Mol Syst Biol
Can ACE2 expression explain SARS-CoV-2 infection of the respiratory epithelia in COVID-19?
Infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) leads to coronavirus disease 2019 (COVID-19), which poses an unprecedented worldwide health crisis, and has been declared a pandemic by the World Health Organization (WHO) on March 11, 2020. The angiotensin converting enzyme 2 (ACE2) has been s...
News
Nawijn, Martijn C;Timens, Wim
10.15252/msb.20209841
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Can ACE2 expression explain SARS-CoV-2 infection of the respiratory epithelia in COVID-19? [Abstract]: Infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) leads to coronavirus disease 2019 (COVID-19), which poses an unprecedented worldwide health crisis, and has been declared a pandemic...
32,623,831
Int J Immunogenet
A role for human leucocyte antigens in the susceptibility to SARS-Cov-2 infection observed in transplant patients.
We analysed data from 80 patients who tested positive for SARS-CoV-2 RNA who had previously been HLA typed to support transplantation. Data were combined from two adjacent centres in Manchester and Leeds to achieve a sufficient number for early analysis. HLA frequencies observed were compared against two control popula...
case/control studies;disease association;disease association studies;genetics;histocompatibility;human leucocyte antigens;immune response;immunology;molecular;population;severe acute respiratory syndrome;virology;virus
Journal Article
Poulton, Kay;Wright, Paul;Hughes, Pamela;Savic, Sinisa;Welberry Smith, Matthew;Guiver, Malcolm;Morton, Muir;van Dellen, David;Tholouli, Eleni;Wynn, Robert;Clark, Brendan
10.1111/iji.12505
[ 0, 1, 1, 1, 0, 0, 0 ]
[Title]: A role for human leucocyte antigens in the susceptibility to SARS-Cov-2 infection observed in transplant patients. [Abstract]: We analysed data from 80 patients who tested positive for SARS-CoV-2 RNA who had previously been HLA typed to support transplantation. Data were combined from two adjacent centres in M...
32,969,973
Curr Opin HIV AIDS
Coronavirus disease-19 vaccine development utilizing promising technology.
PURPOSE OF REVIEW: Coronavirus disease-19 (COVID-19) is a highly transmittable and pathogenic pneumonia-causing disease, which is caused by severe acute respiratory syndrome coronavirus-2, resulting in millions of deaths globally. Severe acute respiratory syndrome coronavirus-2 may coexist with human populations for a ...
Journal Article;Research Support, Non-U.S. Gov't;Review
Wang, Yihan;Xing, Man;Zhou, Dongming
10.1097/COH.0000000000000648
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Coronavirus disease-19 vaccine development utilizing promising technology. [Abstract]: PURPOSE OF REVIEW: Coronavirus disease-19 (COVID-19) is a highly transmittable and pathogenic pneumonia-causing disease, which is caused by severe acute respiratory syndrome coronavirus-2, resulting in millions of deaths glo...
32,501,374
Chaos Solitons Fractals
COVID-19 spreading in Rio de Janeiro, Brazil: Do the policies of social isolation really work?
The recent Coronavirus has been spreading through all the world fastly. In this work we focus on the evolution of the COVID-19 in one of the most populous Brazilian states, namely the Rio de Janeiro state. The first case was reported in March 5, 2020, thus we have a considerable amount of available data to make a good ...
collective phenomena;data analysis;dynamics of social systems;epidemic modeling
Journal Article
Crokidakis, Nuno
10.1016/j.chaos.2020.109930
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 spreading in Rio de Janeiro, Brazil: Do the policies of social isolation really work? [Abstract]: The recent Coronavirus has been spreading through all the world fastly. In this work we focus on the evolution of the COVID-19 in one of the most populous Brazilian states, namely the Rio de Janeiro state...
32,674,826
J Am Med Dir Assoc
Home-Based Primary Care Led-Outbreak Mitigation in Assisted Living Facilities in the First 100 Days of Coronavirus Disease 2019.
Residents of congregate care settings have been severely impacted by the current Coronavirus disease 2019 (COVID-19) pandemic. In this report, we describe the methods our home-based primary care practice has developed to mitigate the spread of COVID-19 in assisted living facilities (ALFs) and we present an initial eval...
covid-19;coronavirus;assisted living;home-based primary care;outbreak
Journal Article;Multicenter Study
Mills, William R;Buccola, Janet M;Sender, Susan;Lichtefeld, Joseph;Romano, Nicholas;Reynolds, Karen;Price, Melissa;Phipps, Jennifer;White, Leigh;Howard, Shauen
10.1016/j.jamda.2020.06.014
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Home-Based Primary Care Led-Outbreak Mitigation in Assisted Living Facilities in the First 100 Days of Coronavirus Disease 2019. [Abstract]: Residents of congregate care settings have been severely impacted by the current Coronavirus disease 2019 (COVID-19) pandemic. In this report, we describe the methods our...
32,864,388
Open Forum Infect Dis
COVID-19 in Hospitalized Adults With HIV.
Background: The spread of SARS-CoV-2 and the COVID-19 pandemic have caused significant morbidity and mortality worldwide. The clinical characteristics and outcomes of hospitalized patients with SARS-CoV-2 and HIV co-infection remain uncertain. Methods: We conducted a matched retrospective cohort study of adults hospita...
hiv;coronavirus disease 2019;severe acute respiratory syndrome coronavirus 2
Journal Article
Stoeckle, Kate;Johnston, Carrie D;Jannat-Khah, Deanna P;Williams, Samuel C;Ellman, Tanya M;Vogler, Mary A;Gulick, Roy M;Glesby, Marshall J;Choi, Justin J
10.1093/ofid/ofaa327
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: COVID-19 in Hospitalized Adults With HIV. [Abstract]: Background: The spread of SARS-CoV-2 and the COVID-19 pandemic have caused significant morbidity and mortality worldwide. The clinical characteristics and outcomes of hospitalized patients with SARS-CoV-2 and HIV co-infection remain uncertain. Methods: We c...
32,907,684
Disaster Med Public Health Prep
Optimizing Scarce Resource Allocation During COVID-19: Rapid Creation of a Regional Health-Care Coalition and Triage Teams in San Diego County, California.
Successful management of an event where health-care needs exceed regional health-care capacity requires coordinated strategies for scarce resource allocation. Publications for rapid development, training, and coordination of regional hospital triage teams to manage the allocation of scarce resources during coronavirus ...
capacity building;disaster medicine;health-care rationing;mass casualty incidents;triage
Journal Article
Devereaux, Asha;Yang, Holly;Seda, Gilbert;Sankar, Viji;Maves, Ryan C;Karanjia, Navaz;Parrish, John Scott;Rosenberg, Christy;Goodman-Crews, Paula;Cederquist, Lynette;Burkle, Frederick M;Tuteur, Jennifer;Leroy, Chiara;Koenig, Kristi L
10.1017/dmp.2020.344
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Optimizing Scarce Resource Allocation During COVID-19: Rapid Creation of a Regional Health-Care Coalition and Triage Teams in San Diego County, California. [Abstract]: Successful management of an event where health-care needs exceed regional health-care capacity requires coordinated strategies for scarce resou...
33,000,106
Ann Acad Med Singap
Characteristics and Outcomes of COVID-19 Patients with Respiratory Failure Admitted to a "Pandemic Ready" Intensive Care Unit - Lessons from Singapore.
INTRODUCTION: Singapore was one of the first countries affected by the coronavirus disease 2019 (COVID-19) pandemic but has been able to prevent its healthcare system and intensive care units (ICU) from being overwhelmed. We describe the clinical features, management and outcomes of COVID-19 patients with respiratory f...
Journal Article
Chew, Si Yuan;Lee, Yee Shay;Ghimiray, Deepak;Tan, Chee Keat;Chua, Gerald Sw
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Characteristics and Outcomes of COVID-19 Patients with Respiratory Failure Admitted to a "Pandemic Ready" Intensive Care Unit - Lessons from Singapore. [Abstract]: INTRODUCTION: Singapore was one of the first countries affected by the coronavirus disease 2019 (COVID-19) pandemic but has been able to prevent it...
32,607,232
Multidiscip Respir Med
First COVID-19 sub-intensive respiratory unit in Europe: the Italian experience.
European SARS-CoV-2 pandemic epicenter was detected in Northern Italy, in a little Italian town of Lodi province, the Lodi Hospital was therefore rapidly saturated, and in particularly the departments of respiratory diseases and Intensive Care Unit had been largely involved. In this paper, we describe how the first Sub...
ards;covid-19;department organization;severe pneumonia;sub-intensive respiratory unit;ventilation
Journal Article
Henchi, Sonia;Conti, Clara Benedetta;Vanoni, Nicolo;Repossi, Alice Claudia;Cipolla, Giuseppe;Marra, Mirko;Esposti, Elena;Fiini, Michela;Raimondi Cominesi, Irene;Crepaldi, Monica;Scozzafava, Mariano
10.4081/mrm.2020.682
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: First COVID-19 sub-intensive respiratory unit in Europe: the Italian experience. [Abstract]: European SARS-CoV-2 pandemic epicenter was detected in Northern Italy, in a little Italian town of Lodi province, the Lodi Hospital was therefore rapidly saturated, and in particularly the departments of respiratory di...
33,071,794
Front Pharmacol
COVID-19: Is There Evidence for the Use of Herbal Medicines as Adjuvant Symptomatic Therapy?
Background: Current recommendations for the self-management of SARS-Cov-2 disease (COVID-19) include self-isolation, rest, hydration, and the use of NSAID in case of high fever only. It is expected that many patients will add other symptomatic/adjuvant treatments, such as herbal medicines. Aims: To provide a benefits/r...
covid-19;benefit/risk assessment;coronavirus (2019-ncov);herbal medicine;respiratory diseases
Journal Article;Review
Silveira, Damaris;Prieto-Garcia, Jose Maria;Boylan, Fabio;Estrada, Omar;Fonseca-Bazzo, Yris Maria;Jamal, Claudia Masrouah;Magalhaes, Perola Oliveira;Pereira, Edson Oliveira;Tomczyk, Michal;Heinrich, Michael
10.3389/fphar.2020.581840
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: COVID-19: Is There Evidence for the Use of Herbal Medicines as Adjuvant Symptomatic Therapy? [Abstract]: Background: Current recommendations for the self-management of SARS-Cov-2 disease (COVID-19) include self-isolation, rest, hydration, and the use of NSAID in case of high fever only. It is expected that man...
32,281,757
G Ital Nefrol
[Covid-19 in patients on dialysis: infection prevention and control strategies].
Covid-19 is a disease caused by a new coronavirus presenting a variability of flu-like symptoms including fever, cough, myalgia and fatigue; in severe cases, patients develop pneumonia, acute respiratory distress syndrome, sepsis and septic shock, that can result in their death. This infection, which was declared a glo...
covid-19;hemodialysis;prevention;transmission
Journal Article
Brioni, Elena;Leopaldi, Donato;Magnaghi, Cristiano;Franchetti, Rosalia;Granellini, Elisa;Pegoraro, Marisa;Gambirasio, Maria Cristina;Mazzacani, Paolo;Parisotto, Maria Teresa
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [Covid-19 in patients on dialysis: infection prevention and control strategies]. [Abstract]: Covid-19 is a disease caused by a new coronavirus presenting a variability of flu-like symptoms including fever, cough, myalgia and fatigue; in severe cases, patients develop pneumonia, acute respiratory distress syndr...
33,041,830
Front Pharmacol
Pathophysiology and Potential Therapeutic Candidates for COVID-19: A Poorly Understood Arena.
Coronavirus disease 2019 (COVID-19), an acute onset pneumonia caused by a novel Betacoronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in the Wuhan City of China in December 2019 and evolved into a global pandemic. To date, there are no proven drugs or vaccines against this virus. Hence,...
anti-inflammatory;antiviral;coronavirus disease 2019;drug repurposing;immunotherapy;pathophysiology;severe acute respiratory syndrome coronavirus 2
Journal Article;Review
Samaddar, Arghadip;Grover, Malika;Nag, Vijaya Lakshmi
10.3389/fphar.2020.585888
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Pathophysiology and Potential Therapeutic Candidates for COVID-19: A Poorly Understood Arena. [Abstract]: Coronavirus disease 2019 (COVID-19), an acute onset pneumonia caused by a novel Betacoronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in the Wuhan City of China in December...
32,457,048
Ann Rheum Dis
Clinical characteristics and outcomes of patients with coronavirus disease 2019 (COVID-19) and rheumatic disease: a comparative cohort study from a US 'hot spot'.
OBJECTIVE: To investigate differences in manifestations and outcomes of coronavirus disease 2019 (COVID-19) infection between those with and without rheumatic disease. METHODS: We conducted a comparative cohort study of patients with rheumatic disease and COVID-19 (confirmed by severe acute respiratory syndrome coronav...
autoimmune diseases;epidemiology;health services research;outcome and process assessment, health care
Comparative Study;Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
D'Silva, Kristin M;Serling-Boyd, Naomi;Wallwork, Rachel;Hsu, Tiffany;Fu, Xiaoqing;Gravallese, Ellen M;Choi, Hyon K;Sparks, Jeffrey A;Wallace, Zachary S
10.1136/annrheumdis-2020-217888
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical characteristics and outcomes of patients with coronavirus disease 2019 (COVID-19) and rheumatic disease: a comparative cohort study from a US 'hot spot'. [Abstract]: OBJECTIVE: To investigate differences in manifestations and outcomes of coronavirus disease 2019 (COVID-19) infection between those with...
32,854,317
J Clin Med
Pulmonary Rehabilitation: Time for an Upgrade.
Pulmonary rehabilitation is a notoriously known but highly underused intervention aimed to restore or improve functional capacity, symptom management and health-related quality of life among patients with chronic respiratory diseases. Since early 1980s, pulmonary rehabilitation has been acknowledged as a comprehensive ...
covid-19;pulmonary rehabilitation;tele-rehabilitation
Editorial
Sebio-Garcia, Raquel
10.3390/jcm9092742
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Pulmonary Rehabilitation: Time for an Upgrade. [Abstract]: Pulmonary rehabilitation is a notoriously known but highly underused intervention aimed to restore or improve functional capacity, symptom management and health-related quality of life among patients with chronic respiratory diseases. Since early 1980s...
32,726,291
Radiol Oncol
Impact of COVID-19 on cancer diagnosis and management in Slovenia - preliminary results.
Background The COVID-19 pandemic has disrupted the provision and use of healthcare services throughout the world. In Slovenia, an epidemic was officially declared between mid-March and mid-May 2020. Although all non-essential health care services were put on hold by government decree, oncological services were listed a...
covid;cancer;delay in diagnosis;referral
Journal Article
Zadnik, Vesna;Mihor, Ana;Tomsic, Sonja;Zagar, Tina;Bric, Nika;Lokar, Katarina;Oblak, Irena
10.2478/raon-2020-0048
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Impact of COVID-19 on cancer diagnosis and management in Slovenia - preliminary results. [Abstract]: Background The COVID-19 pandemic has disrupted the provision and use of healthcare services throughout the world. In Slovenia, an epidemic was officially declared between mid-March and mid-May 2020. Although al...
32,648,667
Cancer Med
COVID-19 pandemic and impact on cancer clinical trials: An academic medical center perspective.
The COVID-19 pandemic changed health-care operations around the world and has interrupted standard clinical practices as well as created clinical research challenges for cancer patients. Cancer patients are uniquely susceptible to COVID-19 infection and have some of the worst outcomes. Importantly, cancer therapeutics ...
covid-19;cancer;clinical trials;oncology;pandemic
Journal Article;Research Support, Non-U.S. Gov't
Marcum, Michelle;Kurtzweil, Nicky;Vollmer, Christine;Schmid, Lisa;Vollmer, Ashley;Kastl, Alison;Acker, Kelly;Gulati, Shuchi;Grover, Punita;Herzog, Thomas J;Ahmad, Syed A;Sohal, Davendra;Wise-Draper, Trisha M
10.1002/cam4.3292
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 pandemic and impact on cancer clinical trials: An academic medical center perspective. [Abstract]: The COVID-19 pandemic changed health-care operations around the world and has interrupted standard clinical practices as well as created clinical research challenges for cancer patients. Cancer patients ...
32,401,215
J Med Internet Res
Telehealth Home Support During COVID-19 Confinement for Community-Dwelling Older Adults With Mild Cognitive Impairment or Mild Dementia: Survey Study.
BACKGROUND: The public health emergency of coronavirus disease (COVID-19) is rapidly evolving worldwide; some countries, including Spain, have implemented restrictive measures. Populations that are vulnerable to this outbreak and its physical and mental health effects include community-dwelling older adults with mild c...
covid-19;cognitive impairment;confinement;coronavirus;dementia;elderly;emergency response;mental health;older adults;physical health;public health;telehealth;well-being
Journal Article;Research Support, Non-U.S. Gov't
Goodman-Casanova, Jessica Marian;Dura-Perez, Elena;Guzman-Parra, Jose;Cuesta-Vargas, Antonio;Mayoral-Cleries, Fermin
10.2196/19434
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Telehealth Home Support During COVID-19 Confinement for Community-Dwelling Older Adults With Mild Cognitive Impairment or Mild Dementia: Survey Study. [Abstract]: BACKGROUND: The public health emergency of coronavirus disease (COVID-19) is rapidly evolving worldwide; some countries, including Spain, have imple...
32,544,053
Emerg Infect Dis
Seroepidemiologic Study Designs for Determining SARS-COV-2 Transmission and Immunity.
Serologic studies are crucial for clarifying dynamics of the coronavirus disease pandemic. Past work on serologic studies (e.g., during influenza pandemics) has made relevant contributions, but specific conditions of the current situation require adaptation. Although detection of antibodies to measure exposure, immunit...
covid-19;sars-cov-2;coronavirus disease;immunity;respiratory infections;seroepidemiologic;severe acute respiratory syndrome coronavirus 2;study design;viruses;zoonoses
Journal Article
Clapham, Hannah;Hay, James;Routledge, Isobel;Takahashi, Saki;Choisy, Marc;Cummings, Derek;Grenfell, Bryan;Metcalf, C Jessica E;Mina, Michael;Barraquer, Isabel Rodriguez;Salje, Henrik;Tam, Clarence C
10.3201/eid2609.201840
[ 0, 1, 0, 0, 1, 0, 0 ]
[Title]: Seroepidemiologic Study Designs for Determining SARS-COV-2 Transmission and Immunity. [Abstract]: Serologic studies are crucial for clarifying dynamics of the coronavirus disease pandemic. Past work on serologic studies (e.g., during influenza pandemics) has made relevant contributions, but specific conditions...
32,064,856
Zhonghua Yu Fang Yi Xue Za Zhi
[Early containment strategies and core measures for prevention and control of novel coronavirus pneumonia in China].
In December 2019, novel coronavirus pneumonia epidemic occurred in Wuhan, Hubei Province, and spread rapidly across the country. In the early stages of the epidemic, China adopted the containment strategy and implemented a series of core measures around this strategic point, including social mobilization, strengthening...
containment strategy;core measures;novel coronavirus pneumonia;prevention and control
Journal Article
Chen, W;Wang, Q;Li, Y Q;Yu, H L;Xia, Y Y;Zhang, M L;Qin, Y;Zhang, T;Peng, Z B;Zhang, R C;Yang, X K;Yin, W W;An, Z J;Wu, D;Yin, Z D;Li, S;Chen, Q L;Feng, L Z;Li, Z J;Feng, Z J
10.3760/cma.j.issn.0253-9624.2020.03.003
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [Early containment strategies and core measures for prevention and control of novel coronavirus pneumonia in China]. [Abstract]: In December 2019, novel coronavirus pneumonia epidemic occurred in Wuhan, Hubei Province, and spread rapidly across the country. In the early stages of the epidemic, China adopted th...
32,627,299
Diabetes Obes Metab
Diabetes, obesity and COVID-19: A complex interplay.
With the accumulation of observational data showing an association of metabolic co-morbidities with adverse outcomes from COVID-19, there is a need to disentangle the contributions of pre-existing macro- and microvascular disease, obesity and glycaemia. This article outlines the complex mechanistic and clinical interpl...
Journal Article
Vas, Prashanth;Hopkins, David;Feher, Michael;Rubino, Francesco;B Whyte, Martin
10.1111/dom.14134
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Diabetes, obesity and COVID-19: A complex interplay. [Abstract]: With the accumulation of observational data showing an association of metabolic co-morbidities with adverse outcomes from COVID-19, there is a need to disentangle the contributions of pre-existing macro- and microvascular disease, obesity and gly...
32,897,438
Radiologe
[Radiological manifestations of pulmonary diseases in COVID-19].
CLINICAL ISSUE: Since its emergence in late 2019, the disease caused by the novel coronavirus, termed COVID-19, has been declared a pandemic by the World Health Organization. Reference standard for the diagnosis of COVID-19 is a positive reverse transcription polymerase chain reaction (RT-PCR) test. While the RT-PCR sh...
areas of consolidation;computed tomography;differential diagnosis;fibrotic lung parenchyma;ground glass opacifications
Journal Article;Review
Heidinger, Benedikt H;Kifjak, Daria;Prayer, Florian;Beer, Lucian;Milos, Ruxandra-Iulia;Rohrich, Sebastian;Arndt, Hanka;Prosch, Helmut
10.1007/s00117-020-00749-4
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: [Radiological manifestations of pulmonary diseases in COVID-19]. [Abstract]: CLINICAL ISSUE: Since its emergence in late 2019, the disease caused by the novel coronavirus, termed COVID-19, has been declared a pandemic by the World Health Organization. Reference standard for the diagnosis of COVID-19 is a posit...
32,597,100
Monaldi Arch Chest Dis
COVID-19 and restrictive lung disease: A deadly combo to trip off the fine balance.
Coronavirus Disease (COVID-19) pandemic has so far led to innumerable deaths worldwide. The risk factors so far that have been most studied as poor prognostic factors are old age, individuals with multiple comorbidities and immunocompromised patients. Amongst the chronic lung diseases, most patients with COVID-19 repor...
Case Reports;Journal Article
Sahu, Kamal Kant;Mishra, Ajay Kumar;Martin, Kevin;Chastain, Iryna
10.4081/monaldi.2020.1346
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: COVID-19 and restrictive lung disease: A deadly combo to trip off the fine balance. [Abstract]: Coronavirus Disease (COVID-19) pandemic has so far led to innumerable deaths worldwide. The risk factors so far that have been most studied as poor prognostic factors are old age, individuals with multiple comorbidi...
32,905,711
Diabetes Technol Ther
The Digital/Virtual Diabetes Clinic: The Future Is Now-Recommendations from an International Panel on Diabetes Digital Technologies Introduction.
The increasing prevalence of diabetes, combined with a growing global shortage of health care professionals (HCP), necessitates the need to develop new approaches to diabetes care delivery to expand access to care, lessen the burden on people with diabetes, improve efficiencies, and reduce the unsustainable financial l...
agp;connected devices;digital tools;telemedicine;type 1 diabetes;type 2 diabetes
Journal Article;Research Support, Non-U.S. Gov't
Phillip, Moshe;Bergenstal, Richard M;Close, Kelly L;Danne, Thomas;Garg, Satish;Heinemann, Lutz;Hirsch, Irl B;Kovatchev, Boris;Laffel, Lori M;Mohan, Viswanathan;Parkin, Christopher G;Battelino, Tadej
10.1089/dia.2020.0375
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The Digital/Virtual Diabetes Clinic: The Future Is Now-Recommendations from an International Panel on Diabetes Digital Technologies Introduction. [Abstract]: The increasing prevalence of diabetes, combined with a growing global shortage of health care professionals (HCP), necessitates the need to develop new a...
32,643,641
Lung India
The N-95 mask: invaluable ally in the battle against the COVID-19 pandemic.
The present COVID-19 pandemic, caused by the airborne SARS-CoV-2 virus, has highlighted the vital importance of appropriate personal protective equipment for all exposed health care workers. The single most important part of this armor is the N-95 mask. With the awareness that the virus is spread by both droplets and t...
decontamination measures;n-95 mask;extended use;personal protective equipment
Journal Article;Review
Udwadia, Zarir F;Raju, Reyma Sara
10.4103/lungindia.lungindia_339_20
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The N-95 mask: invaluable ally in the battle against the COVID-19 pandemic. [Abstract]: The present COVID-19 pandemic, caused by the airborne SARS-CoV-2 virus, has highlighted the vital importance of appropriate personal protective equipment for all exposed health care workers. The single most important part o...
33,059,711
Virol J
Harnessing the immune system to overcome cytokine storm and reduce viral load in COVID-19: a review of the phases of illness and therapeutic agents.
BACKGROUND: Coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2, previously named 2019-nCov), a novel coronavirus that emerged in China in December 2019 and was declared a global pandemic by World Health Organization by March 11th, 2020. Severe manifestations of ...
acute respiratory distress syndrome;angiotensin converting enzyme 2;antiviral;covid-19;chloroquine;cytokine release syndrome;immunotherapy;pathophysiology;sars-cov-2;tocilizumab
Journal Article;Research Support, Non-U.S. Gov't;Review
Khadke, Sumanth;Ahmed, Nayla;Ahmed, Nausheen;Ratts, Ryan;Raju, Shine;Gallogly, Molly;de Lima, Marcos;Sohail, Muhammad Rizwan
10.1186/s12985-020-01415-w
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: Harnessing the immune system to overcome cytokine storm and reduce viral load in COVID-19: a review of the phases of illness and therapeutic agents. [Abstract]: BACKGROUND: Coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2, previously named 2019-nCov),...
32,379,199
Pediatr Infect Dis J
A Case of Critically Ill Infant of Coronavirus Disease 2019 With Persistent Reduction of T Lymphocytes.
BACKGROUND: The outbreak of coronavirus disease 2019 (COVID-19) is becoming a global threat. However, our understanding of the clinical characteristics and treatment of critically ill pediatric patients and their ability of transmitting the coronavirus that causes COVID-19 still remains inadequate because only a handfu...
Case Reports;Journal Article;Research Support, Non-U.S. Gov't
Qiu, Liru;Jiao, Rong;Zhang, Aiming;Chen, Xi;Ning, Qin;Fang, Feng;Zeng, Fang;Tian, Niannian;Zhang, Yi;Huang, Yafei;Sun, Ziyan;Dhuromsingh, Menaka;Li, Hao;Li, Yang;Xu, Rongrong;Chen, Yu;Luo, Xiaoping
10.1097/INF.0000000000002720
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: A Case of Critically Ill Infant of Coronavirus Disease 2019 With Persistent Reduction of T Lymphocytes. [Abstract]: BACKGROUND: The outbreak of coronavirus disease 2019 (COVID-19) is becoming a global threat. However, our understanding of the clinical characteristics and treatment of critically ill pediatric p...
32,822,911
Cytokine
A combinational approach to restore cytokine balance and to inhibit virus growth may promote patient recovery in severe COVID-19 cases.
The COVID-19 pandemic has led to twin public health and economic crises around the world. Not only has it cost hundreds of thousands of lives but also severely impacted livelihoods and placed enormous strain on community healthcare and welfare services. In this review, we explore the events associated with SARS-CoV-2 p...
adam17;adam17/tace inhibitor;covid-19;il-6;sars-cov-2;tace;therapy;sgp130fc
Journal Article;Review
Mahmud-Al-Rafat, Abdullah;Muzammal Haque Asim, Md;Taylor-Robinson, Andrew W;Majumder, Apurba;Muktadir, Abdul;Muktadir, Hasneen;Karim, Mahbubul;Khan, Imran;Mainul Ahasan, Mohammad;Morsaline Billah, Md
10.1016/j.cyto.2020.155228
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: A combinational approach to restore cytokine balance and to inhibit virus growth may promote patient recovery in severe COVID-19 cases. [Abstract]: The COVID-19 pandemic has led to twin public health and economic crises around the world. Not only has it cost hundreds of thousands of lives but also severely imp...
32,760,350
Front Endocrinol (Lausanne)
Association Between Diabetes and COVID-19: A Retrospective Observational Study With a Large Sample of 1,880 Cases in Leishenshan Hospital, Wuhan.
Aims: This study aimed to investigate the clinical courses and outcomes of diabetes mellitus patients with coronavirus disease 2019 (COVID-19) in Wuhan. Methods: This study enrolled 1,880 consecutive patients with confirmed COVID-19 in Leishenshan Hospital. We collected and analyzed their data, including demographic da...
coronavirus disease 2019 (covid-19);clinical courses;comorbidity;diabetes mellitus;prognosis
Journal Article;Observational Study
Liu, Zeming;Li, Jinpeng;Huang, Jianglong;Guo, Liang;Gao, Rongfen;Luo, Kuan;Zeng, Guang;Zhang, Tingbao;Yi, Meilin;Huang, Yihui;Chen, Jincao;Yang, Yibin;Wu, Xiaohui
10.3389/fendo.2020.00478
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Association Between Diabetes and COVID-19: A Retrospective Observational Study With a Large Sample of 1,880 Cases in Leishenshan Hospital, Wuhan. [Abstract]: Aims: This study aimed to investigate the clinical courses and outcomes of diabetes mellitus patients with coronavirus disease 2019 (COVID-19) in Wuhan. ...
32,449,420
Aging Male
Interpretation of arrhythmogenic effects of COVID-19 disease through ECG.
Objective: We aimed to detect the malignant arrhythmic potential of COVID-19 with surface electrocardiographic (ECG) markers.Material and method: Of the ECG parameters PR, QT, QTc, QTd, TPe, and Tpe/QTc were measured in 51 COVID-19 patients and 40 in control subjects.Results: Compared to control group mean QTc (410.8 +...
covid-19;ecg;malignant arrhythmia;qt prolongation
Journal Article
Ozturk, Fatih;Karaduman, Medeni;Coldur, Rabia;Incecik, Saban;Gunes, Yilmaz;Tuncer, Mustafa
10.1080/13685538.2020.1769058
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Interpretation of arrhythmogenic effects of COVID-19 disease through ECG. [Abstract]: Objective: We aimed to detect the malignant arrhythmic potential of COVID-19 with surface electrocardiographic (ECG) markers.Material and method: Of the ECG parameters PR, QT, QTc, QTd, TPe, and Tpe/QTc were measured in 51 CO...
32,503,823
In Vivo
A New Method for Testing Filtration Efficiency of Mask Materials Under Sneeze-like Pressure.
BACKGROUND: Sneezes produce many pathogen-containing micro-droplets with high velocities of 4.5-50.0 m/s. Face masks are believed to protect people from infection by blocking those droplets. However, current filtration efficiency tests can't evaluate masks under sneeze-like pressure. The goal of this study was to estab...
micro-droplets;sars-cov-2;filtration efficiency;mask materials;pandemics;sneeze velocity
Comparative Study;Journal Article
Xiao, L I;Sakagami, Hiroshi;Miwa, Nobuhiko
10.21873/invivo.11955
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: A New Method for Testing Filtration Efficiency of Mask Materials Under Sneeze-like Pressure. [Abstract]: BACKGROUND: Sneezes produce many pathogen-containing micro-droplets with high velocities of 4.5-50.0 m/s. Face masks are believed to protect people from infection by blocking those droplets. However, curren...
32,596,339
Biomed Res Int
D-Dimer and Prothrombin Time Are the Significant Indicators of Severe COVID-19 and Poor Prognosis.
Objective: To investigate the value of coagulation indicators D-dimer (DD), prothrombin time (PT), activated partial thromboplastin time (APTT), thrombin time (TT), and fibrinogen (Fg) in predicting the severity and prognosis of COVID-19. Methods: A total of 115 patients with confirmed COVID-19, who were admitted to Ti...
Journal Article
Long, Hui;Nie, Lan;Xiang, Xiaochen;Li, Huan;Zhang, Xiaoli;Fu, Xiaozhi;Ren, Hongwei;Liu, Wanxin;Wang, Qiang;Wu, Qingming
10.1155/2020/6159720
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: D-Dimer and Prothrombin Time Are the Significant Indicators of Severe COVID-19 and Poor Prognosis. [Abstract]: Objective: To investigate the value of coagulation indicators D-dimer (DD), prothrombin time (PT), activated partial thromboplastin time (APTT), thrombin time (TT), and fibrinogen (Fg) in predicting t...
33,009,914
Database (Oxford)
A database resource and online analysis tools for coronaviruses on a historical and global scale.
The recent outbreak of COVID-19 caused by a new zoonotic origin coronavirus (SARS-CoV-2 or 2019-nCoV) has sound the alarm for the potential spread of epidemic coronavirus crossing species. With the urgent needs to assist disease control and to provide invaluable scientific information, we developed the coronavirus data...
2019-ncov;covid-19;sars-cov-2;coronavirus
Journal Article
Zhu, Zhenglin;Meng, Kaiwen;Liu, Gexin;Meng, Geng
10.1093/database/baaa070
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: A database resource and online analysis tools for coronaviruses on a historical and global scale. [Abstract]: The recent outbreak of COVID-19 caused by a new zoonotic origin coronavirus (SARS-CoV-2 or 2019-nCoV) has sound the alarm for the potential spread of epidemic coronavirus crossing species. With the urg...
32,423,584
Lancet
Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial.
BACKGROUND: No specific antiviral drug has been proven effective for treatment of patients with severe coronavirus disease 2019 (COVID-19). Remdesivir (GS-5734), a nucleoside analogue prodrug, has inhibitory effects on pathogenic animal and human coronaviruses, including severe acute respiratory syndrome coronavirus 2 ...
Journal Article;Multicenter Study;Randomized Controlled Trial
Wang, Yeming;Zhang, Dingyu;Du, Guanhua;Du, Ronghui;Zhao, Jianping;Jin, Yang;Fu, Shouzhi;Gao, Ling;Cheng, Zhenshun;Lu, Qiaofa;Hu, Yi;Luo, Guangwei;Wang, Ke;Lu, Yang;Li, Huadong;Wang, Shuzhen;Ruan, Shunan;Yang, Chengqing;Mei, Chunlin;Wang, Yi;Ding, Dan;Wu, Feng;Tang, Xin;Ye, Xianzhi;Ye, Yingchun;Liu, Bing;Yang, Jie;Yin, ...
10.1016/S0140-6736(20)31022-9
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial. [Abstract]: BACKGROUND: No specific antiviral drug has been proven effective for treatment of patients with severe coronavirus disease 2019 (COVID-19). Remdesivir (GS-5734), a nucleoside analogue prodr...
32,522,278
J Hematol Oncol
Cancer history is an independent risk factor for mortality in hospitalized COVID-19 patients: a propensity score-matched analysis.
BACKGROUND: Although research on the effects of comorbidities on coronavirus disease 2019 (COVID-19) patients is increasing, the risk of cancer history has not been evaluated for the mortality of patients with COVID-19. METHODS: In this retrospective study, we included 3232 patients with pathogen-confirmed COVID-19 who...
covid-19;cancer history, independent risk factor;comorbidities;mortality;sars-cov-2
Journal Article
Meng, Yifan;Lu, Wanrong;Guo, Ensong;Liu, Jia;Yang, Bin;Wu, Ping;Lin, Shitong;Peng, Ting;Fu, Yu;Li, Fuxia;Wang, Zizhuo;Li, Yuan;Xiao, Rourou;Liu, Chen;Huang, Yuhan;Lu, Funian;Wu, Xue;You, Lixin;Ma, Ding;Sun, Chaoyang;Wu, Peng;Chen, Gang
10.1186/s13045-020-00907-0
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Cancer history is an independent risk factor for mortality in hospitalized COVID-19 patients: a propensity score-matched analysis. [Abstract]: BACKGROUND: Although research on the effects of comorbidities on coronavirus disease 2019 (COVID-19) patients is increasing, the risk of cancer history has not been eva...
32,878,619
BMC Med
COVID-19 length of hospital stay: a systematic review and data synthesis.
BACKGROUND: The COVID-19 pandemic has placed an unprecedented strain on health systems, with rapidly increasing demand for healthcare in hospitals and intensive care units (ICUs) worldwide. As the pandemic escalates, determining the resulting needs for healthcare resources (beds, staff, equipment) has become a key prio...
bed demand;covid-19;hospitalisation;icu capacity;length of stay;sars-cov-2
Journal Article;Research Support, Non-U.S. Gov't;Systematic Review
Rees, Eleanor M;Nightingale, Emily S;Jafari, Yalda;Waterlow, Naomi R;Clifford, Samuel;B Pearson, Carl A;Group, Cmmid Working;Jombart, Thibaut;Procter, Simon R;Knight, Gwenan M
10.1186/s12916-020-01726-3
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 length of hospital stay: a systematic review and data synthesis. [Abstract]: BACKGROUND: The COVID-19 pandemic has placed an unprecedented strain on health systems, with rapidly increasing demand for healthcare in hospitals and intensive care units (ICUs) worldwide. As the pandemic escalates, determin...
32,407,708
Cell Host Microbe
The Challenges of Vaccine Development against a New Virus during a Pandemic.
The rapid emergence of a highly pathogenic, readily transmissible coronavirus has resulted in a global pandemic, affecting millions and destabilizing economies. This catastrophe triggered a clarion call for the immediate deployment of a protective vaccine. We describe the unique challenges of developing a vaccine again...
Journal Article;Research Support, N.I.H., Extramural;Research Support, N.I.H., Intramural;Research Support, U.S. Gov't, Non-P.H.S.
Diamond, Michael S;Pierson, Theodore C
10.1016/j.chom.2020.04.021
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: The Challenges of Vaccine Development against a New Virus during a Pandemic. [Abstract]: The rapid emergence of a highly pathogenic, readily transmissible coronavirus has resulted in a global pandemic, affecting millions and destabilizing economies. This catastrophe triggered a clarion call for the immediate d...
32,565,620
Chaos Solitons Fractals
A nonlinear epidemiological model considering asymptotic and quarantine classes for SARS CoV-2 virus.
In this article, we develop a mathematical model considering susceptible, exposed, infected, asymptotic, quarantine/isolation and recovered classes as in case of COVID-19 disease. The facility of quarantine/isolation have been provided to both exposed and infected classes. Asymptotic individuals either recovered withou...
92-02;92b99;lyapunov's function;prophylaxis;reproduction number
Journal Article
Mishra, A M;Purohit, S D;Owolabi, K M;Sharma, Y D
10.1016/j.chaos.2020.109953
[ 0, 0, 1, 0, 1, 1, 0 ]
[Title]: A nonlinear epidemiological model considering asymptotic and quarantine classes for SARS CoV-2 virus. [Abstract]: In this article, we develop a mathematical model considering susceptible, exposed, infected, asymptotic, quarantine/isolation and recovered classes as in case of COVID-19 disease. The facility of q...
32,716,892
J Med Internet Res
The Internet Hospital Plus Drug Delivery Platform for Health Management During the COVID-19 Pandemic: Observational Study.
BACKGROUND: Widespread access to the internet has boosted the emergence of online hospitals. A new outpatient service called "internet hospital plus drug delivery" (IHDD) has been developed in China, but little is known about this platform. OBJECTIVE: The aim of this study is to investigate the characteristics, accepta...
covid-19;ihdd;drug delivery;health management;internet hospital;internet hospital plus drug delivery
Journal Article;Observational Study;Research Support, Non-U.S. Gov't
Ding, Liang;She, Qiuru;Chen, Fengxian;Chen, Zitong;Jiang, Meifang;Huang, Huasi;Li, Yujin;Liao, Chaofeng
10.2196/19678
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The Internet Hospital Plus Drug Delivery Platform for Health Management During the COVID-19 Pandemic: Observational Study. [Abstract]: BACKGROUND: Widespread access to the internet has boosted the emergence of online hospitals. A new outpatient service called "internet hospital plus drug delivery" (IHDD) has b...
32,576,332
Disaster Med Public Health Prep
Assessment of Countries' Preparedness and Lockdown Effectiveness in Fighting COVID-19.
OBJECTIVES: The aim of this study was to assess the risks in confronting the coronavirus disease 2019 (COVID-19) pandemic and the ongoing lockdown effectiveness in each of Italy, Germany, Spain, France, and the United States using China's lockdown model simulation, and cases forecast until the plateau phase. METHODS: Q...
covid-19;icu capacity;forecast;lockdown;pandemic
Journal Article
Amer, Faten;Hammoud, Sahar;Farran, Bashar;Boncz, Imre;Endrei, Dora
10.1017/dmp.2020.217
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Assessment of Countries' Preparedness and Lockdown Effectiveness in Fighting COVID-19. [Abstract]: OBJECTIVES: The aim of this study was to assess the risks in confronting the coronavirus disease 2019 (COVID-19) pandemic and the ongoing lockdown effectiveness in each of Italy, Germany, Spain, France, and the U...
33,029,573
HRB Open Res
Covid-19 Estimating the burden of symptomatic disease in the community and the impact of public health measures on physical, mental and social wellbeing: a study protocol.
Introduction: Covid-19 was declared a pandemic in March 2020. Since then, governments have implemented unprecedented public health measures to contain the virus. This study will provide evidence to inform responses to the pandemic by: i) estimating population prevalence and trends of self-reported symptoms of Covid-19 ...
virus diseases;behaviour and behaviour mechanisms;epidemiology;mathematical modelling;mental health;network dynamics;non-pharmaceutical interventions;public health
Journal Article
Troya, M Isabela;Khashan, Ali;Kearney, Patricia;Arensman, Ella;Hoevel, Philipp;Buckley, Claire;Fitzgerald, Margaret;Humphries, Rory;Kiely, Elizabeth;Mulchrone, Kieran;Murphy, Mike;O'Connor, Lois;O'Donnell, Joan;O'Reilly, Eilis;O'Riordain, Micheal;Spillane, Mary;Wieczorek, Sebastian;Perry, Ivan J
10.12688/hrbopenres.13103.1
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Covid-19 Estimating the burden of symptomatic disease in the community and the impact of public health measures on physical, mental and social wellbeing: a study protocol. [Abstract]: Introduction: Covid-19 was declared a pandemic in March 2020. Since then, governments have implemented unprecedented public hea...
32,835,199
Lancet Digit Health
Effects of human mobility restrictions on the spread of COVID-19 in Shenzhen, China: a modelling study using mobile phone data.
Background: Restricting human mobility is an effective strategy used to control disease spread. However, whether mobility restriction is a proportional response to control the ongoing COVID-19 pandemic is unclear. We aimed to develop a model that can quantify the potential effects of various intracity mobility restrict...
Journal Article;Research Support, Non-U.S. Gov't
Zhou, Ying;Xu, Renzhe;Hu, Dongsheng;Yue, Yang;Li, Qingquan;Xia, Jizhe
10.1016/S2589-7500(20)30165-5
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: Effects of human mobility restrictions on the spread of COVID-19 in Shenzhen, China: a modelling study using mobile phone data. [Abstract]: Background: Restricting human mobility is an effective strategy used to control disease spread. However, whether mobility restriction is a proportional response to control...
32,795,833
Med Hypotheses
SARS-CoV-2 infection and impact on female genital tract: An untested hypothesis.
COVID pandemic consists one of the most challenging medical realities. Apart from affecting respiratory system, current evidence has demonstrated multiorgan manifestations that SARS-Cov-2 infection may actually have. However, one of the medical hypotheses not yet thoroughly tested is the impact on female reproductive s...
Journal Article
Vavoulidis, Eleftherios;Margioula-Siarkou, Chrysoula;Petousis, Stamatios;Dinas, Konstantinos
10.1016/j.mehy.2020.110162
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: SARS-CoV-2 infection and impact on female genital tract: An untested hypothesis. [Abstract]: COVID pandemic consists one of the most challenging medical realities. Apart from affecting respiratory system, current evidence has demonstrated multiorgan manifestations that SARS-Cov-2 infection may actually have. H...
32,092,483
Infect Genet Evol
Genetic diversity and evolution of SARS-CoV-2.
COVID-19 is a viral respiratory illness caused by a new coronavirus called SARS-CoV-2. The World Health Organization declared the SARS-CoV-2 outbreak a global public health emergency. We performed genetic analyses of eighty-six complete or near-complete genomes of SARS-CoV-2 and revealed many mutations and deletions on...
coronavirus;genomic diversity;mutations;sars-cov-2
Journal Article;Research Support, Non-U.S. Gov't
Phan, Tung
10.1016/j.meegid.2020.104260
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Genetic diversity and evolution of SARS-CoV-2. [Abstract]: COVID-19 is a viral respiratory illness caused by a new coronavirus called SARS-CoV-2. The World Health Organization declared the SARS-CoV-2 outbreak a global public health emergency. We performed genetic analyses of eighty-six complete or near-complet...
32,725,866
ACR Open Rheumatol
A Pharmacokinetics-Informed Approach to Navigating Hydroxychloroquine Shortages in Patients With Rheumatic Disease During the COVID-19 Pandemic.
OBJECTIVE: The recent hydroxychloroquine (HCQ) shortage due to use in coronavirus disease 2019 (COVID-19) has forced some rheumatic disease patients to choose between continuing their current dose of HCQ but exhaust their supply early or ration it in order to prolong its use. Blood HCQ concentrations are directly corre...
Journal Article
Scheetz, Marc H;Konig, Maximilian F;Robinson, Philip C;Sparks, Jeffrey A;Kim, Alfred H J
10.1002/acr2.11164
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: A Pharmacokinetics-Informed Approach to Navigating Hydroxychloroquine Shortages in Patients With Rheumatic Disease During the COVID-19 Pandemic. [Abstract]: OBJECTIVE: The recent hydroxychloroquine (HCQ) shortage due to use in coronavirus disease 2019 (COVID-19) has forced some rheumatic disease patients to ch...
32,231,374
PLoS One
Data-based analysis, modelling and forecasting of the COVID-19 outbreak.
Since the first suspected case of coronavirus disease-2019 (COVID-19) on December 1st, 2019, in Wuhan, Hubei Province, China, a total of 40,235 confirmed cases and 909 deaths have been reported in China up to February 10, 2020, evoking fear locally and internationally. Here, based on the publicly available epidemiologi...
Journal Article
Anastassopoulou, Cleo;Russo, Lucia;Tsakris, Athanasios;Siettos, Constantinos
10.1371/journal.pone.0230405
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: Data-based analysis, modelling and forecasting of the COVID-19 outbreak. [Abstract]: Since the first suspected case of coronavirus disease-2019 (COVID-19) on December 1st, 2019, in Wuhan, Hubei Province, China, a total of 40,235 confirmed cases and 909 deaths have been reported in China up to February 10, 2020...
32,383,809
J Am Geriatr Soc
Risk Factors for Mortality in 244 Older Adults With COVID-19 in Wuhan, China: A Retrospective Study.
BACKGROUND/OBJECTIVES: Previous studies have reported that older patients may experience worse outcome(s) after infection with severe acute respiratory syndrome coronavirus-2 than younger individuals. This study aimed to identify potential risk factors for mortality in older patients with coronavirus disease 2019 (COVI...
covid-19;mortalityolder patientsrisk factors
Journal Article
Sun, Haiying;Ning, Ruoqi;Tao, Yu;Yu, Chong;Deng, Xiaoyan;Zhao, Caili;Meng, Silu;Tang, Fangxu;Xu, Dong
10.1111/jgs.16533
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Risk Factors for Mortality in 244 Older Adults With COVID-19 in Wuhan, China: A Retrospective Study. [Abstract]: BACKGROUND/OBJECTIVES: Previous studies have reported that older patients may experience worse outcome(s) after infection with severe acute respiratory syndrome coronavirus-2 than younger individual...
32,727,107
Medicina (Kaunas)
Rapid and Impressive Response to a Combined Treatment with Single-Dose Tocilizumab and NIV in a Patient with COVID-19 Pneumonia/ARDS.
Treatment of acute respiratory distress syndrome (ARDS) due to COVID-19 pneumonia (CARDS) represents a clinical challenge, requiring often invasive mechanical ventilation (IMV). Since the pathogenesis of CARDS it probably involves a direct viral attack to pulmonary and endothelium cells, and immune-mediated inflammatio...
covid-19;acute respiratory distress syndrome (ards);case report;cytokines;immunotherapy;inflammation
Case Reports
Cascella, Marco;Mauro, Immacolata;De Blasio, Elvio;Crispo, Anna;Del Gaudio, Alfredo;Bimonte, Sabrina;Cuomo, Arturo;Ascierto, Paolo Antonio
10.3390/medicina56080377
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Rapid and Impressive Response to a Combined Treatment with Single-Dose Tocilizumab and NIV in a Patient with COVID-19 Pneumonia/ARDS. [Abstract]: Treatment of acute respiratory distress syndrome (ARDS) due to COVID-19 pneumonia (CARDS) represents a clinical challenge, requiring often invasive mechanical ventil...
32,804,611
J Hosp Med
Effect of Systemic Glucocorticoids on Mortality or Mechanical Ventilation in Patients With COVID-19.
The efficacy of glucocorticoids in COVID-19 is unclear. This study was designed to determine whether systemic glucocorticoid treatment in COVID-19 patients is associated with reduced mortality or mechanical ventilation. This observational study included 1,806 hospitalized COVID-19 patients; 140 were treated with glucoc...
Journal Article
Keller, Marla J;Kitsis, Elizabeth A;Arora, Shitij;Chen, Jen-Ting;Agarwal, Shivani;Ross, Michael J;Tomer, Yaron;Southern, William
10.12788/jhm.3497
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Effect of Systemic Glucocorticoids on Mortality or Mechanical Ventilation in Patients With COVID-19. [Abstract]: The efficacy of glucocorticoids in COVID-19 is unclear. This study was designed to determine whether systemic glucocorticoid treatment in COVID-19 patients is associated with reduced mortality or me...
32,747,201
Eur Urol
Urolithiasis in the COVID Era: An Opportunity to Reassess Management Strategies.
Delayed evaluation and/or treatment for urolithiasis during the COVID-19 pandemic provide a unique opportunity to organically reassess many well-established stone management strategies. Nonopioid analgesia for renal colic and spontaneous passage trials appear to be two avenues worthy of investigation.
Editorial
Steinberg, Ryan L;Johnson, Brett A;Antonelli, Jodi;Pearle, Margaret S
10.1016/j.eururo.2020.07.019
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Urolithiasis in the COVID Era: An Opportunity to Reassess Management Strategies. [Abstract]: Delayed evaluation and/or treatment for urolithiasis during the COVID-19 pandemic provide a unique opportunity to organically reassess many well-established stone management strategies. Nonopioid analgesia for renal co...
32,558,631
J Gerontol Soc Work
Social Workers Must Address Intersecting Vulnerabilities among Noninstitutionalized, Black, Latinx, and Older Adults of Color during the COVID-19 Pandemic.
Scant attention has been paid to intersecting vulnerabilities experienced by Black, Latinx, and older adults of color (BLOAC) that increase COVID-19 related risks. Structural inequities have resulted in disproportionate rates of chronic conditions and limited access to care. Media coverage, focused on COVID-19 mortalit...
united states;health disparities;isolation;race and racial disparities;religionspirituality
Journal Article;Research Support, N.I.H., Extramural
Ebor, Megan T;Loeb, Tamra B;Trejo, Laura
10.1080/01634372.2020.1779161
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Social Workers Must Address Intersecting Vulnerabilities among Noninstitutionalized, Black, Latinx, and Older Adults of Color during the COVID-19 Pandemic. [Abstract]: Scant attention has been paid to intersecting vulnerabilities experienced by Black, Latinx, and older adults of color (BLOAC) that increase COV...
32,534,129
Am J Kidney Dis
Urgent Peritoneal Dialysis in Patients With COVID-19 and Acute Kidney Injury: A Single-Center Experience in a Time of Crisis in the United States.
At Montefiore Medical Center in The Bronx, NY, the first case of coronavirus disease 2019 (COVID-19) was admitted on March 11, 2020. At the height of the pandemic, there were 855 patients with COVID-19 admitted on April 13, 2020. Due to high demand for dialysis and shortages of staff and supplies, we started an urgent ...
covid nephropathy;covid-19;acute care;acute kidney injury (aki);acute renal failure (arf);continuous renal replacement therapy (crrt);coronavirus;dialysis;intensive care unit (icu);peritoneal dialysis (pd);resource allocation;resource shortage;urgent-start pd
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Sourial, Maryanne Y;Sourial, Mina H;Dalsan, Rochelle;Graham, Jay;Ross, Michael;Chen, Wei;Golestaneh, Ladan
10.1053/j.ajkd.2020.06.001
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Urgent Peritoneal Dialysis in Patients With COVID-19 and Acute Kidney Injury: A Single-Center Experience in a Time of Crisis in the United States. [Abstract]: At Montefiore Medical Center in The Bronx, NY, the first case of coronavirus disease 2019 (COVID-19) was admitted on March 11, 2020. At the height of th...
32,913,038
Postgrad Med J
Is HbA1c an ideal biomarker of well-controlled diabetes?
HbA1c is a biomarker with a central role in the diagnosis and follow-up of patients with diabetes, although not a perfect one. Common comorbidities encountered in patients with diabetes mellitus, such as renal insufficiency, high output states (iron deficiency anaemia, haemolytic anaemia, haemoglobinopathies and pregna...
anaemia;diabetes & endocrinology;general diabetes;haematology
Journal Article;Review
Kaiafa, Georgia;Veneti, Stavroula;Polychronopoulos, George;Pilalas, Dimitrios;Daios, Stylianos;Kanellos, Ilias;Didangelos, Triantafyllos;Pagoni, Stamatina;Savopoulos, Christos
10.1136/postgradmedj-2020-138756
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Is HbA1c an ideal biomarker of well-controlled diabetes? [Abstract]: HbA1c is a biomarker with a central role in the diagnosis and follow-up of patients with diabetes, although not a perfect one. Common comorbidities encountered in patients with diabetes mellitus, such as renal insufficiency, high output state...
32,903,228
J Infect Dev Ctries
Comparison of clinical characteristics between fecal/perianal swab nucleic acid-positive and -negative patients with COVID-19.
INTRODUCTION: We analyzed the clinical characteristics of COVID-19 fecal/perianal swab nucleic acid-positive patients in our hospital and evaluated the effect of SARS-CoV-2 on the gastrointestinal tract. METHODOLOGY: Ninety-seven patients in the Fifth Affiliated Hospital of Sun Yat-sen University from January 17, 2020 ...
ace2;covid-19;pcr;sars-cov-2;clinical characteristics;fecal swab
Comparative Study;Journal Article;Research Support, Non-U.S. Gov't
Chen, Gong-Qi;Luo, Wen-Tao;Zhao, Chao-Hui;Li, Chun-Na;Hong, Zhong-Si;Xia, Jin-Yu;Liu, Xi
10.3855/jidc.12885
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Comparison of clinical characteristics between fecal/perianal swab nucleic acid-positive and -negative patients with COVID-19. [Abstract]: INTRODUCTION: We analyzed the clinical characteristics of COVID-19 fecal/perianal swab nucleic acid-positive patients in our hospital and evaluated the effect of SARS-CoV-2...
32,469,610
JCO Glob Oncol
Mortality and Advanced Support Requirement for Patients With Cancer With COVID-19: A Mathematical Dynamic Model for Latin America.
PURPOSE: In the midst of a global pandemic, evidence suggests that similar to other severe respiratory viral infections, patients with cancer are at higher risk of becoming infected by COVID-19 and have a poorer prognosis. METHODS: We have modeled the mortality and the intensive care unit (ICU) requirement for the care...
Journal Article
Ruiz-Patino, Alejandro;Arrieta, Oscar;Pino, Luis E;Rolfo, Christian;Ricaurte, Luisa;Recondo, Gonzalo;Zatarain-Barron, Zyanya-Lucia;Corrales, Luis;Martin, Claudio;Barron, Feliciano;Vargas, Carlos;Carranza, Hernan;Otero, Jorge;Rodriguez, July;Sotelo, Carolina;Viola, Lucia;Russo, Alessandro;Rosell, Rafael;Cardona, Andres ...
10.1200/GO.20.00156
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Mortality and Advanced Support Requirement for Patients With Cancer With COVID-19: A Mathematical Dynamic Model for Latin America. [Abstract]: PURPOSE: In the midst of a global pandemic, evidence suggests that similar to other severe respiratory viral infections, patients with cancer are at higher risk of beco...
32,763,564
Mar Pollut Bull
Surgical face masks as a potential source for microplastic pollution in the COVID-19 scenario.
Although there have been enormous reports on the microplastic pollution from different plastic products, impacts, controlling mechanisms in recent years, the surgical face masks, made up of polymeric materials, as a source of microplastic pollution potential in the ecosystem are not fully understood and considered yet....
covid-19;disposable plastics;medical face mask;microplastics pollution;plastic production
Journal Article
Aragaw, Tadele Assefa
10.1016/j.marpolbul.2020.111517
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Surgical face masks as a potential source for microplastic pollution in the COVID-19 scenario. [Abstract]: Although there have been enormous reports on the microplastic pollution from different plastic products, impacts, controlling mechanisms in recent years, the surgical face masks, made up of polymeric mate...
32,871,847
In Vivo
Raloxifene and Bazedoxifene Could Be Promising Candidates for Preventing the COVID-19 Related Cytokine Storm, ARDS and Mortality.
The FDA-approved drugs raloxifene and bazedoxifene could be among the best candidates to prevent mortality in severe COVID-19 patients. Raloxifene and bazedoxifene inhibit IL-6 signaling at therapeutic doses, suggesting they have the potential to prevent the cytokine storm, ARDS and mortality in severe COVID-19 patient...
covid-19 therapy;il6;sars-cov-2;bazedoxifene;cytokine storm;lung failure;raloxifene
Journal Article
Smetana, Karel Jr;Rosel, Daniel;BrAbek, Jan
10.21873/invivo.12135
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Raloxifene and Bazedoxifene Could Be Promising Candidates for Preventing the COVID-19 Related Cytokine Storm, ARDS and Mortality. [Abstract]: The FDA-approved drugs raloxifene and bazedoxifene could be among the best candidates to prevent mortality in severe COVID-19 patients. Raloxifene and bazedoxifene inhib...
32,440,665
Arch Acad Emerg Med
Cross-Protection Induced by Encephalitis Vaccines against COVID-19 Might be a Reason for Relatively Lower Mortality Rate in Some Countries.
COronaVIrus Disease 2019 (COVID-19) is an on-going pandemic attributed to a novel virus named SARS-CoV-2. Comparing the statistics of incidence and death rates between nations reveals that there is discrepancy amongst countries in these regards, even between countries that share borders. We herein present information f...
covid-19;encephalitis;heterologous;immunity;japanese encephalitis vaccines;vaccines
Journal Article
Katoh, Shojiro;Obayashi, Toshihiko;Ganesh, Jegatheesan Saravana;Iwasaki, Masaru;Preethy, Senthilkumar;Abraham, Samuel Jk
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Cross-Protection Induced by Encephalitis Vaccines against COVID-19 Might be a Reason for Relatively Lower Mortality Rate in Some Countries. [Abstract]: COronaVIrus Disease 2019 (COVID-19) is an on-going pandemic attributed to a novel virus named SARS-CoV-2. Comparing the statistics of incidence and death rates...
32,349,259
Int J Environ Res Public Health
Covid-19 Outbreak Progression in Italian Regions: Approaching the Peak by the End of March in Northern Italy and First Week of April in Southern Italy.
Epidemiological figures of the SARS-CoV-2 epidemic in Italy are higher than those observed in China. Our objective was to model the SARS-CoV-2 outbreak progression in Italian regions vs. Lombardy to assess the epidemic's progression. Our setting was Italy, and especially Lombardy, which is experiencing a heavy burden o...
covid-19;italian regions;model;outbreak progression;peak
Journal Article
Distante, Cosimo;Piscitelli, Prisco;Miani, Alessandro
10.3390/ijerph17093025
[ 0, 0, 0, 0, 0, 1, 0 ]
[Title]: Covid-19 Outbreak Progression in Italian Regions: Approaching the Peak by the End of March in Northern Italy and First Week of April in Southern Italy. [Abstract]: Epidemiological figures of the SARS-CoV-2 epidemic in Italy are higher than those observed in China. Our objective was to model the SARS-CoV-2 outb...
32,383,576
Eur J Phys Rehabil Med
Up to 2.2 million people experiencing disability suffer collateral damage each day of COVID-19 lockdown in Europe.
BACKGROUND: The COVID-19 pandemic is having a great impact on health services. Patients not receiving care due to closure of outpatient services suffer a collateral damage. Our aim was to provide first data on impact of COVID-19 on people experiencing disability in Europe. METHODS: We developed an estimation from a sur...
Journal Article
Negrini, Stefano;Grabljevec, Klemen;Boldrini, Paolo;Kiekens, Carlotte;Moslavac, Sasa;Zampolini, Mauro;Christodoulou, Nicolas
10.23736/S1973-9087.20.06361-3
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Up to 2.2 million people experiencing disability suffer collateral damage each day of COVID-19 lockdown in Europe. [Abstract]: BACKGROUND: The COVID-19 pandemic is having a great impact on health services. Patients not receiving care due to closure of outpatient services suffer a collateral damage. Our aim was...
32,838,152
SN Compr Clin Med
COVID-19 Infection and Haematological Involvement: a Review of Epidemiology, Pathophysiology and Prognosis of Full Blood Count Findings.
The unfolding COVID-19 pandemic began in December 2019 in Wuhan, Hubei Province. COVID-19 is a systemic infection affecting several systems including the haematopoietic system. Surveys illustrating the laboratory findings of these patients conclude that lymphocytopenia, neutrophilia and thrombocytopenia are prominent a...
covid-19;cytokine release syndrome;lymphocytopenia;neutrophilia;sars-cov-2;thrombocytopenia;white blood cells
Journal Article;Review
Violetis, Odyssefs A;Chasouraki, Angeliki M;Giannou, Alexandra M;Baraboutis, Ioannis G
10.1007/s42399-020-00380-3
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: COVID-19 Infection and Haematological Involvement: a Review of Epidemiology, Pathophysiology and Prognosis of Full Blood Count Findings. [Abstract]: The unfolding COVID-19 pandemic began in December 2019 in Wuhan, Hubei Province. COVID-19 is a systemic infection affecting several systems including the haematop...