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32,348,495
J Infect Dis
Interferon-Induced Transmembrane Protein 3 Genetic Variant rs12252-C Associated With Disease Severity in Coronavirus Disease 2019.
A major unanswered question in the current global coronavirus disease 2019 (COVID-19) outbreak is why severe disease develops in a small minority of infected individuals. In the current article, we report that homozygosity for the C allele of rs12252 in the interferon-induced transmembrane protein 3 (IFITM3) gene is as...
covid-19;ifitm3;rs12252;severe pneumonia
Journal Article
Zhang, Yonghong;Qin, Ling;Zhao, Yan;Zhang, Ping;Xu, Bin;Li, Kang;Liang, Lianchun;Zhang, Chi;Dai, Yanchao;Feng, Yingmei;Sun, Jianping;Hu, Zhongjie;Xiang, Haiping;Knight, Julian C;Dong, Tao;Jin, Ronghua
10.1093/infdis/jiaa224
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Interferon-Induced Transmembrane Protein 3 Genetic Variant rs12252-C Associated With Disease Severity in Coronavirus Disease 2019. [Abstract]: A major unanswered question in the current global coronavirus disease 2019 (COVID-19) outbreak is why severe disease develops in a small minority of infected individual...
32,800,347
Psychosomatics
Psychiatric Aspects of Chloroquine and Hydroxychloroquine Treatment in the Wake of Coronavirus Disease-2019: Psychopharmacological Interactions and Neuropsychiatric Sequelae.
BACKGROUND: Chloroquine and hydroxychloroquine are among several experimental treatments being investigated in the urgent response to the coronavirus disease-2019. With increased use of these medications, physicians need to become knowledgeable of these drugs' neuropsychiatric side effects and interactions with psychia...
covid-19;chloroquine;hydroxychloroquine;neuropsychiatry;psychiatry
Journal Article;Review
Hamm, Brandon S;Rosenthal, Lisa J
10.1016/j.psym.2020.06.022
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Psychiatric Aspects of Chloroquine and Hydroxychloroquine Treatment in the Wake of Coronavirus Disease-2019: Psychopharmacological Interactions and Neuropsychiatric Sequelae. [Abstract]: BACKGROUND: Chloroquine and hydroxychloroquine are among several experimental treatments being investigated in the urgent re...
32,762,651
BMC Gastroenterol
Transplantation during the COVID-19 pandemic: nothing noble is accomplished without danger.
The global health crisis due to the fast spread of coronavirus disease (COVID-19) has caused major disruption in all aspects of healthcare. Transplantation is one of the most affected sectors, as it relies on a variety of services that have been drastically occupied to treat patients affected by COVID-19. With this rep...
covid-19;coronavirus;organ donation;sars-cov-2;transplantation;virus tests
Journal Article;Review
Spoletini, Gabriele;Bianco, Giuseppe;Graceffa, Dario;Lai, Quirino
10.1186/s12876-020-01401-0
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Transplantation during the COVID-19 pandemic: nothing noble is accomplished without danger. [Abstract]: The global health crisis due to the fast spread of coronavirus disease (COVID-19) has caused major disruption in all aspects of healthcare. Transplantation is one of the most affected sectors, as it relies o...
32,344,439
Dtsch Med Wochenschr
[COVID-19-Response - Strategies of the Task-Force Coronavirus and experiences upon implementation in the management of 115 cases at the University Medical Center Freiburg].
BACKGROUND: The new pandemic coronavirus SARS-CoV-2 causing coronavirus disease-2019 (COVID-19) poses immense challenges to health care systems worldwide. In the current manuscript we summarize the strategies, organisational approaches and actions of the Task-force Coronavirus at the University Medical Center Freiburg....
Journal Article
Rieg, Siegbert;Busch, Hans-Jorg;Hans, Felix;Grundmann, Hajo;Biever, Paul;Burkle, Hartmut;Hammer, Thorsten;Thimme, Robert;Kern, Winfried
10.1055/a-1147-6244
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: [COVID-19-Response - Strategies of the Task-Force Coronavirus and experiences upon implementation in the management of 115 cases at the University Medical Center Freiburg]. [Abstract]: BACKGROUND: The new pandemic coronavirus SARS-CoV-2 causing coronavirus disease-2019 (COVID-19) poses immense challenges to he...
32,545,264
J Clin Med
Modelling the Evolution of COVID-19 in High-Incidence European Countries and Regions: Estimated Number of Infections and Impact of Past and Future Intervention Measures.
A previously developed mechanistic model of COVID-19 transmission has been adapted and applied here to study the evolution of the disease and the effect of intervention measures in some European countries and territories where the disease has had a major impact. A clear impact of the major intervention measures on the ...
covid-19;disease transmission model;epidemiology;intervention measures;virus
Journal Article
Fernandez-Recio, Juan
10.3390/jcm9061825
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: Modelling the Evolution of COVID-19 in High-Incidence European Countries and Regions: Estimated Number of Infections and Impact of Past and Future Intervention Measures. [Abstract]: A previously developed mechanistic model of COVID-19 transmission has been adapted and applied here to study the evolution of the...
32,358,689
Radiol Med
COVID-19 outbreak in Italy: experimental chest X-ray scoring system for quantifying and monitoring disease progression.
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new virus recently isolated from humans. SARS-CoV-2 was discovered to be the pathogen responsible for a cluster of pneumonia cases associated with severe respiratory disease that occurred in December 2019 in China. This novel pulmonary infection, formall...
covid-19;chest x-ray;computed tomography;sars-cov-2;scoring system
Journal Article
Borghesi, Andrea;Maroldi, Roberto
10.1007/s11547-020-01200-3
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: COVID-19 outbreak in Italy: experimental chest X-ray scoring system for quantifying and monitoring disease progression. [Abstract]: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new virus recently isolated from humans. SARS-CoV-2 was discovered to be the pathogen responsible for a cluster o...
33,051,660
J Travel Med
Social consequences of mass quarantine during epidemics: a systematic review with implications for the COVID-19 response.
Four billion people worldwide have experienced coronavirus disease 2019 (COVID-19) confinement. Such unprecedented extent of mobility restriction to curb the COVID-19 pandemic may have profound impacts on how individuals live, travel and retain well-being. This systematic review aims to identify (i) the social conseque...
covid-19;mass quarantine;epidemics;lockdown;pandemics;psychological impact;social consequences
Journal Article;Systematic Review
Chu, Isaac Yen-Hao;Alam, Prima;Larson, Heidi J;Lin, Leesa
10.1093/jtm/taaa192
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Social consequences of mass quarantine during epidemics: a systematic review with implications for the COVID-19 response. [Abstract]: Four billion people worldwide have experienced coronavirus disease 2019 (COVID-19) confinement. Such unprecedented extent of mobility restriction to curb the COVID-19 pandemic m...
32,718,127
Turk J Med Sci
Outcome of Non-Critical COVID-19 Patients with Early Hospitalization and Early Antiviral Treatment Outside the ICU.
Background Despite the COVID-19 pandemic has been going on over 5 months, there is yet to be a standart management policy for all patients including to those mild-to-moderate cases. We evaluated the role of a combined effort of early hospitalization in combination with early antiviral therapy with COVID-19 patients in ...
covid-19;favipiravir;hydroxychloroquine;non-critical illness
Journal Article
Calik BaSaran, Nursel;Uyaroglu, Oguz Abdullah;Telli Dizman, Gulcin;Ozisik, Lale;Sahin, Taha Koray;Tas, Zahit;Inkaya, Ahmet Cagkan;Karahan, Sevilay;Ozyavuz Alp, Sehnaz;Alp, Alpaslan;Metan, Gokhan;Zarakol, Iskin Pinar;Sain Guven, Gulay;Oz, Serife Gul;Topeli, Arzu;Uzun, Omrum;Akova, Murat;Unal, Serhat
10.3906/sag-2006-173
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Outcome of Non-Critical COVID-19 Patients with Early Hospitalization and Early Antiviral Treatment Outside the ICU. [Abstract]: Background Despite the COVID-19 pandemic has been going on over 5 months, there is yet to be a standart management policy for all patients including to those mild-to-moderate cases. W...
32,673,841
Diabetes Metab Syndr
COVID-19 pandemic and its recovery time of patients in India: A pilot study.
BACKGROUND AND AIMS: Covid-19 virus started from Wuhan, China and has brought the world down to its knees. It has catapulted as a venomous global phenomenon. This study focuses on the Covid-19 situation in India and its recovery time. METHOD: The study period is from March 1, 2020 to April 25, 2020. A random sample of ...
covid-19;kaplan-meier;survival curve
Journal Article
Barman, Manash Pratim;Rahman, Tousifur;Bora, Krishnarjun;Borgohain, Chandan
10.1016/j.dsx.2020.07.004
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: COVID-19 pandemic and its recovery time of patients in India: A pilot study. [Abstract]: BACKGROUND AND AIMS: Covid-19 virus started from Wuhan, China and has brought the world down to its knees. It has catapulted as a venomous global phenomenon. This study focuses on the Covid-19 situation in India and its re...
32,635,422
Int J Environ Res Public Health
Provision of Psychotherapy during the COVID-19 Pandemic among Czech, German and Slovak Psychotherapists.
Psychotherapists around the world are facing an unprecedented situation with the outbreak of the novel coronavirus disease (COVID-19). To combat the rapid spread of the virus, direct contact with others has to be avoided when possible. Therefore, remote psychotherapy provides a valuable option to continue mental health...
covid-19;fear of infection;psychotherapy;public health;remote psychotherapy
Journal Article
Humer, Elke;Pieh, Christoph;Kuska, Martin;Barke, Antonia;Doering, Bettina K;Gossmann, Katharina;Trnka, Radek;Meier, Zdenek;Kascakova, Natalia;Tavel, Peter;Probst, Thomas
10.3390/ijerph17134811
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Provision of Psychotherapy during the COVID-19 Pandemic among Czech, German and Slovak Psychotherapists. [Abstract]: Psychotherapists around the world are facing an unprecedented situation with the outbreak of the novel coronavirus disease (COVID-19). To combat the rapid spread of the virus, direct contact wit...
33,072,417
Turk J Obstet Gynecol
Pregnancy worsens the morbidity of COVID-19 and this effect becomes more prominent as pregnancy advances.
Objective: To investigate pregnancy outcomes and compare the clinical characteristics of coronavirus 2019 (COVID-19) disease in pregnant and agematched non-pregnant women. Materials and Methods: Hospital records of four tertiary care centers were reviewed retrospectively. The subjects comprised 188 pregnant patients an...
covid-19;sars-cov-2;intensive care unit admission;morbidity;pregnancy;preterm birth
Journal Article
Tug, Niyazi;Yassa, Murat;Kole, Emre;Sakin, Onder;Cakir Kole, Merve;Karateke, Ates;Yiyit, Nurettin;Yavuz, Emre;Birol, Pinar;Budak, Dogus;Kol, Omer;Emir, Edip
10.4274/tjod.galenos.2020.38924
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Pregnancy worsens the morbidity of COVID-19 and this effect becomes more prominent as pregnancy advances. [Abstract]: Objective: To investigate pregnancy outcomes and compare the clinical characteristics of coronavirus 2019 (COVID-19) disease in pregnant and agematched non-pregnant women. Materials and Methods...
32,603,484
J Med Virol
Matrix metalloproteinase 3 as a valuable marker for patients with COVID-19.
The situation of the coronavirus disease 2019 (COVID-19) continues to evolve, our study explored the significance of serum levels of matrix metalloproteinase 3 (MMP3) as a marker for patients with COVID-19. Sixty-two COVID-19 patients in the First Hospital of Hunan University of Chinese Medicine and Loudi Center for Di...
covid-19;mmp3 concentrations;inflammation
Journal Article;Research Support, Non-U.S. Gov't
Shi, Shengjie;Su, Min;Shen, Ge;Hu, Yan;Yi, Fan;Zeng, Ziyan;Zhu, Pan;Yang, Gang;Zhou, Hui;Li, Qiong;Xie, Xiaobing
10.1002/jmv.26235
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Matrix metalloproteinase 3 as a valuable marker for patients with COVID-19. [Abstract]: The situation of the coronavirus disease 2019 (COVID-19) continues to evolve, our study explored the significance of serum levels of matrix metalloproteinase 3 (MMP3) as a marker for patients with COVID-19. Sixty-two COVID-...
32,644,899
Telemed J E Health
Rapid Telehealth-Centered Response to COVID-19 Outbreaks in Postacute and Long-Term Care Facilities.
Purpose: The vulnerability of postacute and long-term care (PA/LTC) facility residents to COVID-19 has manifested across the world with increasing facility outbreaks associated with high hospitalization and mortality rates. Systematic protocols to guide telehealth-centered interventions in response to COVID-19 outbreak...
pandemic;telehealth;telemedicine;telenursing
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Harris, Drew A;Archbald-Pannone, Laurie;Kaur, Jasveen;Cattell-Gordon, David;Rheuban, Karen S;Ombres, Rachel L;Albero, Kimberly;Steele, Rebecca;Bell, Taison D;Mutter, Justin B
10.1089/tmj.2020.0236
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Rapid Telehealth-Centered Response to COVID-19 Outbreaks in Postacute and Long-Term Care Facilities. [Abstract]: Purpose: The vulnerability of postacute and long-term care (PA/LTC) facility residents to COVID-19 has manifested across the world with increasing facility outbreaks associated with high hospitaliza...
32,587,094
J Biol Chem
SARS-CoV-2 (COVID-19) structural and evolutionary dynamicome: Insights into functional evolution and human genomics.
The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has challenged the speed at which laboratories can discover the viral composition and study health outcomes. The small approximately 30-kb ssRNA genome of coronaviruses makes them adept at cross-species spread while enabling a robust un...
covid-19;rna virus;human genetics;molecular dynamics;molecular evolution;post-translational modification (ptm);protein structure;receptor structure-function;severe acute respiratory coronavirus 2 (sars-cov-2);virus entry
Journal Article;Research Support, N.I.H., Extramural
Gupta, Ruchir;Charron, Jacob;Stenger, Cynthia L;Painter, Jared;Steward, Hunter;Cook, Taylor W;Faber, William;Frisch, Austin;Lind, Eric;Bauss, Jacob;Li, Xiaopeng;Sirpilla, Olivia;Soehnlen, Xavier;Underwood, Adam;Hinds, David;Morris, Michele;Lamb, Neil;Carcillo, Joseph A;Bupp, Caleb;Uhal, Bruce D;Rajasekaran, Surender;Pr...
10.1074/jbc.RA120.014873
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: SARS-CoV-2 (COVID-19) structural and evolutionary dynamicome: Insights into functional evolution and human genomics. [Abstract]: The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has challenged the speed at which laboratories can discover the viral composition and study health...
32,967,465
Eur J Ophthalmol
Intravitreal injections during COVID-19 outbreak: Real-world experience from an Italian tertiary referral center.
We report our experience during COVID-19 outbreak for intravitreal injections in patients with maculopathy. We proposed a treatment priority levels and timings; the "High" priority level includes all monocular patients; the "Moderate" is assigned to all patients with an active macular neovascularization; the patients a...
age-related macular degeneration;central serous chorioretinopathy;diabetic macular edema;practice management;retina;retina - medical therapies;socioeconomics and education in medicine/ophthalmology;venous occlusive disease
Editorial
Carnevali, Adriano;Giannaccare, Giuseppe;Gatti, Valentina;Scuteri, Gianfranco;Randazzo, Giorgio;Scorcia, Vincenzo
10.1177/1120672120962032
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Intravitreal injections during COVID-19 outbreak: Real-world experience from an Italian tertiary referral center. [Abstract]: We report our experience during COVID-19 outbreak for intravitreal injections in patients with maculopathy. We proposed a treatment priority levels and timings; the "High" priority leve...
32,401,210
J Med Internet Res
Mining the Characteristics of COVID-19 Patients in China: Analysis of Social Media Posts.
BACKGROUND: In December 2019, pneumonia cases of unknown origin were reported in Wuhan City, Hubei Province, China. Identified as the coronavirus disease (COVID-19), the number of cases grew rapidly by human-to-human transmission in Wuhan. Social media, especially Sina Weibo (a major Chinese microblogging social media ...
covid-19;sars-cov-2;sina weibo;coronavirus disease;help;social media
Journal Article;Research Support, Non-U.S. Gov't
Huang, Chunmei;Xu, Xinjie;Cai, Yuyang;Ge, Qinmin;Zeng, Guangwang;Li, Xiaopan;Zhang, Weide;Ji, Chen;Yang, Ling
10.2196/19087
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Mining the Characteristics of COVID-19 Patients in China: Analysis of Social Media Posts. [Abstract]: BACKGROUND: In December 2019, pneumonia cases of unknown origin were reported in Wuhan City, Hubei Province, China. Identified as the coronavirus disease (COVID-19), the number of cases grew rapidly by human-t...
32,723,467
J Coll Physicians Surg Pak
Urgent, Emergent, or Elective Surgery during the COVID-19 Pandemic.
Null.
Journal Article
Karampelias, Vasileios;Spanidis, Ypatios;Zografos, Constantinos D
10.29271/jcpsp.2020.Supp1.S86
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Urgent, Emergent, or Elective Surgery during the COVID-19 Pandemic. [Abstract]: Null. [Keywords]:
33,043,110
Inform Med Unlocked
Exploration of surface glycoprotein to design multi-epitope vaccine for the prevention of Covid-19.
Stimulation and generation of T and B cell-mediated long-term immune response are essential for the curbing of a deadly virus such as SAR-CoV-2 (Severe Acute Respiratory Corona Virus 2). Immunoinformatics approach in vaccine design takes advantage of antigenic and non-allergenic epitopes present on the spike glycoprote...
covid-19;immunity;sars-cov-2;subunit vaccine;tlrs
Journal Article
Oladipo, Elijah Kolawole;Ajayi, Ayodeji Folorunsho;Ariyo, Olumuyiwa Elijah;Onile, Samson Olugbenga;Jimah, Esther Moradeyo;Ezediuno, Louis Odinakaose;Adebayo, Oluwadunsin Iyanuoluwa;Adebayo, Emmanuel Tayo;Odeyemi, Aduragbemi Noah;Oyeleke, Marvellous Oluwaseun;Oyewole, Moyosoluwa Precious;Oguntomi, Ayomide Samuel;Akindiy...
10.1016/j.imu.2020.100438
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Exploration of surface glycoprotein to design multi-epitope vaccine for the prevention of Covid-19. [Abstract]: Stimulation and generation of T and B cell-mediated long-term immune response are essential for the curbing of a deadly virus such as SAR-CoV-2 (Severe Acute Respiratory Corona Virus 2). Immunoinform...
32,475,006
Oral Dis
Coronaviridae-Old friends, new enemy!
Coronaviridae is a family of single-stranded positive enveloped RNA viruses. This article aimed to review the history of these viruses in the last 60 years since their discovery to understand what lessons can be learned from the past. A review of the PubMed database was carried out, describing taxonomy, classification,...
coronaviridae;coronavirus;covid-19
Journal Article;Review
Leao, Jair Carneiro;Gusmao, Teresa Paula de Lima;Zarzar, Adriana Machado;Leao Filho, Jair Carneiro;Barkokebas Santos de Faria, Andreza;Morais Silva, Igor Henrique;Gueiros, Luiz Alcino Monteiro;Robinson, Narendran Andrew;Porter, Stephen;Carvalho, Alessandra de Albuquerque Tavares
10.1111/odi.13447
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Coronaviridae-Old friends, new enemy! [Abstract]: Coronaviridae is a family of single-stranded positive enveloped RNA viruses. This article aimed to review the history of these viruses in the last 60 years since their discovery to understand what lessons can be learned from the past. A review of the PubMed dat...
32,278,074
Microbes Infect
Emergency response to the outbreak of COVID-19: the Korean case.
This letter aims to describe how Korea can improve its emergency response to the outbreak of COVID-19. The key finding is that the nation has to shift from a self-interest-oriented response to a shared-interest-oriented response. Similarly, neighboring nations could form a national framework of networks among stakehold...
coronavirus;emergency response;integrated emergency management system;self-interest;shared-interests
Letter
Ha, Kyoo-Man
10.1016/j.micinf.2020.04.001
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Emergency response to the outbreak of COVID-19: the Korean case. [Abstract]: This letter aims to describe how Korea can improve its emergency response to the outbreak of COVID-19. The key finding is that the nation has to shift from a self-interest-oriented response to a shared-interest-oriented response. Simi...
32,873,808
Nat Commun
Tracking the COVID-19 pandemic in Australia using genomics.
Genomic sequencing has significant potential to inform public health management for SARS-CoV-2. Here we report high-throughput genomics for SARS-CoV-2, sequencing 80% of cases in Victoria, Australia (population 6.24 million) between 6 January and 14 April 2020 (total 1,333 COVID-19 cases). We integrate epidemiological,...
Journal Article;Observational Study;Research Support, Non-U.S. Gov't
Seemann, Torsten;Lane, Courtney R;Sherry, Norelle L;Duchene, Sebastian;Goncalves da Silva, Anders;Caly, Leon;Sait, Michelle;Ballard, Susan A;Horan, Kristy;Schultz, Mark B;Hoang, Tuyet;Easton, Marion;Dougall, Sally;Stinear, Timothy P;Druce, Julian;Catton, Mike;Sutton, Brett;van Diemen, Annaliese;Alpren, Charles;Williams...
10.1038/s41467-020-18314-x
[ 0, 0, 1, 1, 0, 0, 0 ]
[Title]: Tracking the COVID-19 pandemic in Australia using genomics. [Abstract]: Genomic sequencing has significant potential to inform public health management for SARS-CoV-2. Here we report high-throughput genomics for SARS-CoV-2, sequencing 80% of cases in Victoria, Australia (population 6.24 million) between 6 Janu...
32,900,426
Dtsch Arztebl Int
Invasive and Non-Invasive Ventilation in Patients With COVID-19.
BACKGROUND: The reported high mortality of COVID-19 patients in intensive care has given rise to a debate over whether patients with this disease are being intubated too soon and might instead benefit from more non-invasive ventilation. METHODS: This review is based on articles published up to 12 June 2020 that were re...
Journal Article;Review
Windisch, Wolfram;Weber-Carstens, Steffen;Kluge, Stefan;Rossaint, Rolf;Welte, Tobias;Karagiannidis, Christian
10.3238/arztebl.2020.0528
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Invasive and Non-Invasive Ventilation in Patients With COVID-19. [Abstract]: BACKGROUND: The reported high mortality of COVID-19 patients in intensive care has given rise to a debate over whether patients with this disease are being intubated too soon and might instead benefit from more non-invasive ventilatio...
32,412,308
Med Anthropol
Chronic Living in a Communicable World.
By April 2020, COVID-19 lockdowns had restricted the movements of over half the world's population. As health authorities advise people living with chronic conditions to self-isolate because they are at particular risk of serious complications and death, the epidemiological split between communicable and noncommunicabl...
covid-19;chronic disease;chronicity;illness work;prioritization
Journal Article
Manderson, Lenore;Wahlberg, Ayo
10.1080/01459740.2020.1761352
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Chronic Living in a Communicable World. [Abstract]: By April 2020, COVID-19 lockdowns had restricted the movements of over half the world's population. As health authorities advise people living with chronic conditions to self-isolate because they are at particular risk of serious complications and death, the ...
32,678,866
Age Ageing
Comparing associations between frailty and mortality in hospitalised older adults with or without COVID-19 infection: a retrospective observational study using electronic health records.
BACKGROUND: The aim of this study was to describe outcomes in hospitalised older people with different levels of frailty and COVID-19 infection. METHODS: We undertook a single centre, retrospective cohort study examining COVID-19 related mortality using Electronic Health Records, for older people (65 and over) with fra...
covid-19;cohort study;frailty;older people
Journal Article;Observational Study;Research Support, Non-U.S. Gov't
Owen, Rhiannon K;Conroy, Simon P;Taub, Nicholas;Jones, Will;Bryden, Daniele;Pareek, Manish;Faull, Christina;Abrams, Keith R;Davis, Daniel;Banerjee, Jay
10.1093/ageing/afaa167
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Comparing associations between frailty and mortality in hospitalised older adults with or without COVID-19 infection: a retrospective observational study using electronic health records. [Abstract]: BACKGROUND: The aim of this study was to describe outcomes in hospitalised older people with different levels of...
33,073,199
ACS Pharmacol Transl Sci
Achilles' Heel of SARS-CoV-2 Structure.
Guided by evolutionarily signaled vulnerabilities in the structure of SARS-CoV-2, we identify epitopes in free monomers of the spike protein that steer the generation of induced or administered antibodies geared at promoting destabilization of the virus quaternary structure, thereby hampering infectivity.
Journal Article
Fernandez, Ariel
10.1021/acsptsci.0c00128
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Achilles' Heel of SARS-CoV-2 Structure. [Abstract]: Guided by evolutionarily signaled vulnerabilities in the structure of SARS-CoV-2, we identify epitopes in free monomers of the spike protein that steer the generation of induced or administered antibodies geared at promoting destabilization of the virus quate...
32,543,745
Pacing Clin Electrophysiol
Low prevalence of arrhythmias in clinically stable COVID-19 patients.
BACKGROUND: No studies investigated the prevalence of arrhythmias among clinically-stable patients affected by COVID-19 infection. METHODS: We assessed prevalence, type, and burden of arrhythmias, by a single-day snapshot in seven non-intensive COVID Units at a third-level center. RESULTS: We enrolled 132 inhospital pa...
covid-19;sars-cov-2;arrhythmias;atrial fibrillation;coronavirus
Journal Article
Sala, Simone;Peretto, Giovanni;De Luca, Giacomo;Farina, Nicola;Campochiaro, Corrado;Tresoldi, Moreno;Dagna, Lorenzo;Zangrillo, Alberto;Gulletta, Simone;Della Bella, Paolo
10.1111/pace.13987
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Low prevalence of arrhythmias in clinically stable COVID-19 patients. [Abstract]: BACKGROUND: No studies investigated the prevalence of arrhythmias among clinically-stable patients affected by COVID-19 infection. METHODS: We assessed prevalence, type, and burden of arrhythmias, by a single-day snapshot in seve...
32,817,409
J Med Ethics
How to overcome lockdown: selective isolation versus contact tracing.
At this stage of the COVID-19 pandemic, two policy aims are imperative: avoiding the need for a general lockdown of the population, with all its economic, social and health costs, and preventing the healthcare system from being overwhelmed by the unchecked spread of infection. Achieving these two aims requires the cons...
coercion;elderly and terminally ill;emergency medicine;ethics;public policy
Journal Article;Comment
White, Lucie;van Basshuysen, Philippe
10.1136/medethics-2020-106680
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: How to overcome lockdown: selective isolation versus contact tracing. [Abstract]: At this stage of the COVID-19 pandemic, two policy aims are imperative: avoiding the need for a general lockdown of the population, with all its economic, social and health costs, and preventing the healthcare system from being o...
32,515,033
Dermatol Ther
Severity and risk of COVID-19 in cancer patients: An evidence-based learning.
The immune system of cancer patient gets compromised because of cancer therapy, surgery, and malignancy and thus the probability of infection are increased than the general patients. Immunosuppression can expose cancer patients to serious complications which can lead to delay in diagnosis and unnecessary hospitalizatio...
covid-19 virus;cancer;health care;malignancy;patient care
Journal Article
Sharma, Akanksha;Malviya, Rishabha;Kumar, Vinod;Gupta, Ramji;Awasthi, Rajendra
10.1111/dth.13778
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Severity and risk of COVID-19 in cancer patients: An evidence-based learning. [Abstract]: The immune system of cancer patient gets compromised because of cancer therapy, surgery, and malignancy and thus the probability of infection are increased than the general patients. Immunosuppression can expose cancer pa...
32,894,923
Korean J Med Educ
Medical students' perspectives on recommencing clinical rotations during coronavirus disease 2019 at one institution in South Korea.
PURPOSE: Clinical rotations of medical students across the world have inevitably been affected due to the coronavirus disease 2019 (COVID-19) pandemic. The aims of this study were to explore medical students' perception on the school's response and management of clinical rotation during the COVID-19 pandemic and on how...
clinical clerkship;covid-19;medical education;professionalism
Journal Article
Park, Jewel;Park, Hyunmi;Lim, Ji-Eun;Rhim, Hye Chang;Lee, Young-Mee
10.3946/kjme.2020.170
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Medical students' perspectives on recommencing clinical rotations during coronavirus disease 2019 at one institution in South Korea. [Abstract]: PURPOSE: Clinical rotations of medical students across the world have inevitably been affected due to the coronavirus disease 2019 (COVID-19) pandemic. The aims of th...
32,913,304
Cell Res
Single-cell transcriptomic atlas of primate cardiopulmonary aging.
Aging is a major risk factor for many diseases, especially in highly prevalent cardiopulmonary comorbidities and infectious diseases including Coronavirus Disease 2019 (COVID-19). Resolving cellular and molecular mechanisms associated with aging in higher mammals is therefore urgently needed. Here, we created young and...
Journal Article;Research Support, Non-U.S. Gov't
Ma, Shuai;Sun, Shuhui;Li, Jiaming;Fan, Yanling;Qu, Jing;Sun, Liang;Wang, Si;Zhang, Yiyuan;Yang, Shanshan;Liu, Zunpeng;Wu, Zeming;Zhang, Sheng;Wang, Qiaoran;Zheng, Aihua;Duo, Shuguang;Yu, Yang;Belmonte, Juan Carlos Izpisua;Chan, Piu;Zhou, Qi;Song, Moshi;Zhang, Weiqi;Liu, Guang-Hui
10.1038/s41422-020-00412-6
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Single-cell transcriptomic atlas of primate cardiopulmonary aging. [Abstract]: Aging is a major risk factor for many diseases, especially in highly prevalent cardiopulmonary comorbidities and infectious diseases including Coronavirus Disease 2019 (COVID-19). Resolving cellular and molecular mechanisms associat...
33,053,371
Cell Syst
A Sweep of Earth's Virome Reveals Host-Guided Viral Protein Structural Mimicry and Points to Determinants of Human Disease.
Viruses deploy genetically encoded strategies to coopt host machinery and support viral replicative cycles. Here, we use protein structure similarity to scan for molecular mimicry, manifested by structural similarity between viral and endogenous host proteins, across thousands of cataloged viruses and hosts spanning br...
covid-19;evolution;mimicry;modeling;pathogen-host interaction;protein structure;virology
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Lasso, Gorka;Honig, Barry;Shapira, Sagi D
10.1016/j.cels.2020.09.006
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: A Sweep of Earth's Virome Reveals Host-Guided Viral Protein Structural Mimicry and Points to Determinants of Human Disease. [Abstract]: Viruses deploy genetically encoded strategies to coopt host machinery and support viral replicative cycles. Here, we use protein structure similarity to scan for molecular mim...
33,004,168
Best Pract Res Clin Anaesthesiol
Best practice in cardiac anesthesia during the COVID-19 pandemic: Practical recommendations.
The COVID-19 outbreak has influenced the entire health care system, including cardiac surgery. In this review, the authors reveal practical aspects that are important during the COVID-19 pandemic with regards to the safe delivery of cardiac anesthesia. Timing for operations of the cardio-vascular system may be well pro...
covid-19;anesthesia;cardiac procedures;pandemics;personal protective equipment
Journal Article;Review
Moka, Eleni;Paladini, Antonella;Rekatsina, Martina;Urits, Ivan;Viswanath, Omar;Kaye, Alan D;Pergolizzi, Joseph V;Yeam, Cheng Teng;Varrassi, Giustino
10.1016/j.bpa.2020.06.008
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Best practice in cardiac anesthesia during the COVID-19 pandemic: Practical recommendations. [Abstract]: The COVID-19 outbreak has influenced the entire health care system, including cardiac surgery. In this review, the authors reveal practical aspects that are important during the COVID-19 pandemic with regar...
32,952,832
Pan Afr Med J
The pandemic COVID-19: a tale of viremia, cellular oxidation and immune dysfunction.
COVID-19, caused by SARS-CoV-2 is a tester of the immune system. While it spares the healthy, it brings severe morbidity and in a few cases, mortality to its victims. This article aims at critically reviewing the key virulence factors of COVID-19 which are the viremia, cellular oxidation and immune dysfunction. The ave...
covid-19;sars-cov-2;cellular oxidation;immune;immunomodulatory;immunoprophylactic;viremia
Journal Article
Rowaiye, Adekunle Babajide;Onuh, Olukemi Adejoke;Oli, Angus Nnamdi;Okpalefe, Okiemute Ajiroghene;Oni, Solomon;Nwankwo, Ezinne Janefrances
10.11604/pamj.2020.36.188.23476
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: The pandemic COVID-19: a tale of viremia, cellular oxidation and immune dysfunction. [Abstract]: COVID-19, caused by SARS-CoV-2 is a tester of the immune system. While it spares the healthy, it brings severe morbidity and in a few cases, mortality to its victims. This article aims at critically reviewing the k...
32,456,720
Infect Control Hosp Epidemiol
COVID-19 infections among HCWs exposed to a patient with a delayed diagnosis of COVID-19.
We report on COVID-19 risk among HCWs exposed to a patient diagnosed with COVID-19 on day 13 of hospitalization. There were 44 HCWs exposed to the patient before contact and droplet precautions were implemented: of these, 2 of 44 (5%) developed COVID-19 potentially attributable to the exposure.
Case Reports;Journal Article
Baker, Meghan A;Rhee, Chanu;Fiumara, Karen;Bennett-Rizzo, Carin;Tucker, Robert;Williams, Sarah A;Wickner, Paige;Beloff, Jennifer;McGrath, Casey;Poulton, Alexa;Klompas, Michael
10.1017/ice.2020.256
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 infections among HCWs exposed to a patient with a delayed diagnosis of COVID-19. [Abstract]: We report on COVID-19 risk among HCWs exposed to a patient diagnosed with COVID-19 on day 13 of hospitalization. There were 44 HCWs exposed to the patient before contact and droplet precautions were implemente...
32,447,087
Environ Res
Exposure to greenspaces could reduce the high global burden of pain.
Painful conditions are among the leading causes of years lived with disability, and may increase following the coronavirus pandemic, which has led to temporary closure of some healthcare services for people with chronic pain. To reduce this burden, novel, cost-effective and accessible interventions are required. We pro...
greenspace;microbiome;pain;public health
Journal Article;Review
Stanhope, Jessica;Breed, Martin F;Weinstein, Philip
10.1016/j.envres.2020.109641
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Exposure to greenspaces could reduce the high global burden of pain. [Abstract]: Painful conditions are among the leading causes of years lived with disability, and may increase following the coronavirus pandemic, which has led to temporary closure of some healthcare services for people with chronic pain. To r...
32,462,445
Eur Radiol
Any unique image biomarkers associated with COVID-19?
OBJECTIVE: To define the uniqueness of chest CT infiltrative features associated with COVID-19 image characteristics as potential diagnostic biomarkers. METHODS: We retrospectively collected chest CT exams including n = 498 on 151 unique patients RT-PCR positive for COVID-19 and n = 497 unique patients with community-a...
biomarkers;covid-19;neural network;pneumonia
Journal Article
Pu, Jiantao;Leader, Joseph;Bandos, Andriy;Shi, Junli;Du, Pang;Yu, Juezhao;Yang, Bohan;Ke, Shi;Guo, Youmin;Field, Jessica B;Fuhrman, Carl;Wilson, David;Sciurba, Frank;Jin, Chenwang
10.1007/s00330-020-06956-w
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Any unique image biomarkers associated with COVID-19? [Abstract]: OBJECTIVE: To define the uniqueness of chest CT infiltrative features associated with COVID-19 image characteristics as potential diagnostic biomarkers. METHODS: We retrospectively collected chest CT exams including n = 498 on 151 unique patient...
33,020,331
Acta Med Indones
Clinical Profile of Elderly Patients with COVID-19 hospitalised in Indonesia's National General Hospital.
Latar BelakangSebanyak 38.6% kasus kematian pasien COVID-19 di Indonesia terjadi di populasi lansia. Data mengenai profil klinis pasien rawat inap lansia dengan COVID-19 masih tidak ada. Padahal kelompok pasien ini adalah pasien risiko tinggi selama pandemi ini yang memerlukan perhatian lebih.MetodeStudi deskriptif ini...
covid-19;clinical profile;elderly;geriatric patient;indonesia
Journal Article;Observational Study
Azwar, Muhammad Khifzhon;Setiati, Siti;Rizka, Aulia;Fitriana, Ika;Saldi, Siti Rizny F;Safitri, Eka Dian
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical Profile of Elderly Patients with COVID-19 hospitalised in Indonesia's National General Hospital. [Abstract]: Latar BelakangSebanyak 38.6% kasus kematian pasien COVID-19 di Indonesia terjadi di populasi lansia. Data mengenai profil klinis pasien rawat inap lansia dengan COVID-19 masih tidak ada. Padaha...
31,986,261
Lancet
A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster.
BACKGROUND: An ongoing outbreak of pneumonia associated with a novel coronavirus was reported in Wuhan city, Hubei province, China. Affected patients were geographically linked with a local wet market as a potential source. No data on person-to-person or nosocomial transmission have been published to date. METHODS: In ...
Journal Article;Research Support, Non-U.S. Gov't
Chan, Jasper Fuk-Woo;Yuan, Shuofeng;Kok, Kin-Hang;To, Kelvin Kai-Wang;Chu, Hin;Yang, Jin;Xing, Fanfan;Liu, Jieling;Yip, Cyril Chik-Yan;Poon, Rosana Wing-Shan;Tsoi, Hoi-Wah;Lo, Simon Kam-Fai;Chan, Kwok-Hung;Poon, Vincent Kwok-Man;Chan, Wan-Mui;Ip, Jonathan Daniel;Cai, Jian-Piao;Cheng, Vincent Chi-Chung;Chen, Honglin;Hui...
10.1016/S0140-6736(20)30154-9
[ 0, 0, 0, 0, 1, 0, 0 ]
[Title]: A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. [Abstract]: BACKGROUND: An ongoing outbreak of pneumonia associated with a novel coronavirus was reported in Wuhan city, Hubei province, China. Affected patients wer...
32,606,565
Curr Trends Immunol
Coronaviruses' sugar shields as vaccine candidates.
A successful global healthcare response relies on versatile vaccines and production of broadly virus-neutralizing antibodies by the immune system to protect us from emerging infectious diseases. The present 2019 severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic highlights the urgent need for develop...
covid-19;n-glycans;sars;sars-cov-2;coronavirus;glyco-conjugate;lectin;oligomannoses;spike glycoprotein;vaccines;virus-neutralizing antibody
Journal Article
Wang, Denong
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Coronaviruses' sugar shields as vaccine candidates. [Abstract]: A successful global healthcare response relies on versatile vaccines and production of broadly virus-neutralizing antibodies by the immune system to protect us from emerging infectious diseases. The present 2019 severe acute respiratory syndrome c...
32,332,334
J Glaucoma
Review of Hygiene and Disinfection Recommendations for Outpatient Glaucoma Care: A COVID Era Update.
This review focuses on best practices and recommendations for hygiene and disinfection to limit exposure and transmission of infection in outpatient glaucoma clinics during the current COVID-19 pandemic.
Journal Article;Review
Shabto, Julie M;De Moraes, Carlos Gustavo;Cioffi, George A;Liebmann, Jeffrey M
10.1097/IJG.0000000000001540
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Review of Hygiene and Disinfection Recommendations for Outpatient Glaucoma Care: A COVID Era Update. [Abstract]: This review focuses on best practices and recommendations for hygiene and disinfection to limit exposure and transmission of infection in outpatient glaucoma clinics during the current COVID-19 pand...
32,558,620
Vasc Med
COVID-19-associated coagulopathy: An exploration of mechanisms.
An ongoing global pandemic of viral pneumonia (coronavirus disease [COVID-19]), due to the virus SARS-CoV-2, has infected millions of people and remains a threat to many more. Most critically ill patients have respiratory failure and there is an international effort to understand mechanisms and predictors of disease se...
covid-19;anticoagulation;antiplatelet;inflammation;neutrophils;thrombosis;vascular endothelium;venous thromboembolism (vte)
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't;Review
Colling, Meaghan E;Kanthi, Yogendra
10.1177/1358863X20932640
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: COVID-19-associated coagulopathy: An exploration of mechanisms. [Abstract]: An ongoing global pandemic of viral pneumonia (coronavirus disease [COVID-19]), due to the virus SARS-CoV-2, has infected millions of people and remains a threat to many more. Most critically ill patients have respiratory failure and t...
32,828,550
Trends Genet
Host Polymorphisms May Impact SARS-CoV-2 Infectivity.
Based on a broad public database compilation, we support the hypothesis that germinal polymorphisms may regulate the expression of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cellular target itself and proteases controlling the process of its shedding or, conversely, its internalization. Consequent...
snp;coronavirus;genetic variation;infection;pharmacogenetics
Journal Article;Research Support, Non-U.S. Gov't
Brest, Patrick;Refae, Sadal;Mograbi, Baharia;Hofman, Paul;Milano, Gerard
10.1016/j.tig.2020.08.003
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Host Polymorphisms May Impact SARS-CoV-2 Infectivity. [Abstract]: Based on a broad public database compilation, we support the hypothesis that germinal polymorphisms may regulate the expression of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cellular target itself and proteases controlling ...
32,921,730
Acta Biomed
Possible modes of transmission of Novel coronavirus SARS-CoV-2: a review.
INTRODUCTION: The widespread outbreak of the novel SARS-CoV-2 has raised numerous questions about the origin and transmission of the virus. Knowledge about the mode of transmission as well as assessing the effectiveness of the preventive measures would aid in containing the outbreak of the coronavirus. Presently, respi...
Journal Article;Research Support, Non-U.S. Gov't;Review
Mukhra, Richa;Krishan, Kewal;Kanchan, Tanuj
10.23750/abm.v91i3.10039
[ 0, 0, 1, 0, 1, 0, 0 ]
[Title]: Possible modes of transmission of Novel coronavirus SARS-CoV-2: a review. [Abstract]: INTRODUCTION: The widespread outbreak of the novel SARS-CoV-2 has raised numerous questions about the origin and transmission of the virus. Knowledge about the mode of transmission as well as assessing the effectiveness of th...
32,943,611
Spinal Cord Ser Cases
A case for inspiratory muscle training in SCI: potential role as a preventative tool in infectious respiratory diseases like COVID-19.
INTRODUCTION: Respiratory complications (RC) are a leading cause of death after spinal cord injury (SCI) due to compromised immune function and respiratory muscle weakness. Thus, individuals with SCI are at high risk of developing COVID-19 related RC. Results of a SCI clinical trial showed a supervised respiratory musc...
Case Reports;Journal Article;Research Support, Non-U.S. Gov't;Review
Palermo, Anne E;Cahalin, Lawrence P;Nash, Mark S
10.1038/s41394-020-00337-7
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: A case for inspiratory muscle training in SCI: potential role as a preventative tool in infectious respiratory diseases like COVID-19. [Abstract]: INTRODUCTION: Respiratory complications (RC) are a leading cause of death after spinal cord injury (SCI) due to compromised immune function and respiratory muscle w...
32,327,866
Math Methods Appl Sci
Dynamic models for Coronavirus Disease 2019 and data analysis.
In this letter, two time delay dynamic models, a Time Delay Dynamical-Novel Coronavirus Pneumonia (TDD-NCP) model and Fudan-Chinese Center for Disease Control and Prevention (CCDC) model, are introduced to track the data of Coronavirus Disease 2019 (COVID-19). The TDD-NCP model was developed recently by Chengars group ...
Journal Article
Shao, Nian;Zhong, Min;Yan, Yue;Pan, HanShuang;Cheng, Jin;Chen, Wenbin
10.1002/mma.6345
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Dynamic models for Coronavirus Disease 2019 and data analysis. [Abstract]: In this letter, two time delay dynamic models, a Time Delay Dynamical-Novel Coronavirus Pneumonia (TDD-NCP) model and Fudan-Chinese Center for Disease Control and Prevention (CCDC) model, are introduced to track the data of Coronavirus ...
32,276,848
J Microbiol Immunol Infect
Prolonged viral shedding in feces of pediatric patients with coronavirus disease 2019.
OBJECTIVE: To determine the dynamic changes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in respiratory and fecal specimens in children with coronavirus disease 2019 (COVID-19). METHODS: From January 17, 2020 to February 23, 2020, three paediatric cases of COVID-19 were reported in Qingdao, Shand...
covid-19;fecal shedding;pediatric patient;sars-cov-2
Journal Article;Review
Xing, Yu-Han;Ni, Wei;Wu, Qin;Li, Wen-Jie;Li, Guo-Ju;Wang, Wen-Di;Tong, Jian-Ning;Song, Xiu-Feng;Wing-Kin Wong, Gary;Xing, Quan-Sheng
10.1016/j.jmii.2020.03.021
[ 0, 1, 1, 0, 1, 0, 0 ]
[Title]: Prolonged viral shedding in feces of pediatric patients with coronavirus disease 2019. [Abstract]: OBJECTIVE: To determine the dynamic changes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in respiratory and fecal specimens in children with coronavirus disease 2019 (COVID-19). METHODS: Fr...
32,953,129
Can J Kidney Health Dis
An Interprofessional Approach in Caring for a Patient on Maintenance Hemodialysis with COVID-19 in Toronto, Canada: An Educational Case Report.
Rationale: Hemodialysis patients are at significant risk from COVID-19 due to their frequent interaction with the health care system and medical comorbidities. We followed up the trajectory of the first COVID-19-positive maintenance hemodialysis patient at Sunnybrook Health Sciences Centre in Toronto. We present the le...
critical illness;hemodialysis;illness trajectory;infectious diseases;quality improvement
Journal Article
Hendren, Elizabeth M;Matthews, Nicola;Oliver, Mathew;Rice, Julie;Tobe, Sheldon W;Auguste, Bourne L
10.1177/2054358120957473
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: An Interprofessional Approach in Caring for a Patient on Maintenance Hemodialysis with COVID-19 in Toronto, Canada: An Educational Case Report. [Abstract]: Rationale: Hemodialysis patients are at significant risk from COVID-19 due to their frequent interaction with the health care system and medical comorbidit...
32,516,064
Stroke
Acute Stroke in Times of the COVID-19 Pandemic: A Multicenter Study.
BACKGROUND AND PURPOSE: This study aims to assess the number of patients with acute ischemic cerebrovascular events seeking in-patient medical emergency care since the implementation of social distancing measures in the coronavirus disease 2019 (COVID-19) pandemic. METHODS: In this retrospective multicenter study, data...
brain ischemia;pandemics;reperfusion;stroke;thrombectomy
Journal Article;Multicenter Study;Research Support, Non-U.S. Gov't
Hoyer, Carolin;Ebert, Anne;Huttner, Hagen B;Puetz, Volker;Kallmunzer, Bernd;Barlinn, Kristian;Haverkamp, Christian;Harloff, Andreas;Brich, Jochen;Platten, Michael;Szabo, Kristina
10.1161/STROKEAHA.120.030395
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Acute Stroke in Times of the COVID-19 Pandemic: A Multicenter Study. [Abstract]: BACKGROUND AND PURPOSE: This study aims to assess the number of patients with acute ischemic cerebrovascular events seeking in-patient medical emergency care since the implementation of social distancing measures in the coronaviru...
32,596,474
Sci Adv
Evidence for host-dependent RNA editing in the transcriptome of SARS-CoV-2.
The COVID-19 outbreak has become a global health risk, and understanding the response of the host to the SARS-CoV-2 virus will help to combat the disease. RNA editing by host deaminases is an innate restriction process to counter virus infection, but it is not yet known whether this process operates against coronavirus...
Journal Article;Research Support, Non-U.S. Gov't
Di Giorgio, Salvatore;Martignano, Filippo;Torcia, Maria Gabriella;Mattiuz, Giorgio;Conticello, Silvestro G
10.1126/sciadv.abb5813
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Evidence for host-dependent RNA editing in the transcriptome of SARS-CoV-2. [Abstract]: The COVID-19 outbreak has become a global health risk, and understanding the response of the host to the SARS-CoV-2 virus will help to combat the disease. RNA editing by host deaminases is an innate restriction process to c...
32,665,127
Cytokine Growth Factor Rev
Are we fully exploiting type I Interferons in today's fight against COVID-19 pandemic?
Coronavirus disease 2019 (COVID-19) first emerged in late 2019 in China. At the time of writing, its causative agent SARS-CoV-2 has spread worldwide infecting over 9 million individuals and causing more than 460,000 deaths. In the absence of vaccines, we are facing the dramatic challenge of controlling COVID-19 pandemi...
antiviral immune response;antiviral therapy;beta interferon;covid-19;coronavirus;immunomodulation;mucosal treatments;sars-cov-2;type i interferons
Journal Article;Review
Arico, Eleonora;Bracci, Laura;Castiello, Luciano;Gessani, Sandra;Belardelli, Filippo
10.1016/j.cytogfr.2020.07.010
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Are we fully exploiting type I Interferons in today's fight against COVID-19 pandemic? [Abstract]: Coronavirus disease 2019 (COVID-19) first emerged in late 2019 in China. At the time of writing, its causative agent SARS-CoV-2 has spread worldwide infecting over 9 million individuals and causing more than 460,...
33,015,725
J Thromb Thrombolysis
The experience of Hamad General Hospital collaborative anticoagulation clinic in Qatar during the COVID-19 pandemic.
Hamad General Hospital Anticoagulation Clinic is one of the largest collaborative-practice clinics of its type in Qatar. The patients being followed at this clinic are typically complex and vulnerable. During the coronavirus disease 2019 pandemic, measures were implemented at the clinic to minimize the exposure of pati...
anticoagulation;covid-19;clinical pharmacy;collaborative practice;social distancing;warfarin
Journal Article
Abdallah, Ibtihal;Eltahir, Asma;Fernyhough, Liam;El-Bardissy, Ahmed;Ahmed, Rana;Abdulgelil, Mohammed;Elgaily, Dina;Mohammed, AbdulMoqeeth;Jassim, Ameena;Barakat, Loluwa;Al-Ansari, Mazen;Javed, Mehak;Alkhawaja, Raja;Elzouki, Abdel-Nasser
10.1007/s11239-020-02276-4
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The experience of Hamad General Hospital collaborative anticoagulation clinic in Qatar during the COVID-19 pandemic. [Abstract]: Hamad General Hospital Anticoagulation Clinic is one of the largest collaborative-practice clinics of its type in Qatar. The patients being followed at this clinic are typically comp...
32,340,091
Zhonghua Liu Xing Bing Xue Za Zhi
[Epidemic characteristics and trend analysis of the COVID-19 in Hubei province].
Objective: By describing and analyzing the epidemic characteristics and trends of the attack rate, the crude mortality and relevant indexes in Hubei province during the pandemic of COVID-19 to provide comprehensive evaluations of the epidemic trends and the effects of intervention measures. Methods: Based on the case d...
attack rate;covid-19;mortality
English Abstract;Journal Article
Song, Y;Liu, M;Jia, W P;Wang, S S;Cao, W Z;Han, K;Yang, S S;Li, J;Chen, Z;He, Y
10.3760/cma.j.cn112338-20200321-00409
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [Epidemic characteristics and trend analysis of the COVID-19 in Hubei province]. [Abstract]: Objective: By describing and analyzing the epidemic characteristics and trends of the attack rate, the crude mortality and relevant indexes in Hubei province during the pandemic of COVID-19 to provide comprehensive eva...
32,772,281
Intern Emerg Med
The COVID-19 epidemic and reorganisation of triage, an observational study.
Recent studies have suggested different organisational strategies, modifying Emergency Departments (EDs) during the COVID-19 epidemic. However, real data on the practical application of these strategies are not yet available. The objective of this study is to evaluate the inclusion of pre-triage during the COVID-19 out...
covid-19;coronavirus;emergency;emergency department;medicine;pre-triage;triage
Journal Article;Observational Study
Turcato, Gianni;Zaboli, Arian;Pfeifer, Norbert
10.1007/s11739-020-02465-2
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The COVID-19 epidemic and reorganisation of triage, an observational study. [Abstract]: Recent studies have suggested different organisational strategies, modifying Emergency Departments (EDs) during the COVID-19 epidemic. However, real data on the practical application of these strategies are not yet availabl...
32,493,713
J Med Ethics
Medical students and COVID-19: the need for pandemic preparedness.
The COVID-19 pandemic has prompted unprecedented global disruption. For medical schools, this has manifested as examination and curricular restructuring as well as significant changes to clinical attachments. With the available evidence suggesting that medical students' mental health status is already poorer than that ...
education;education/programs;emergency medicine
Journal Article
O'Byrne, Lorcan;Gavin, Blanaid;McNicholas, Fiona
10.1136/medethics-2020-106353
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Medical students and COVID-19: the need for pandemic preparedness. [Abstract]: The COVID-19 pandemic has prompted unprecedented global disruption. For medical schools, this has manifested as examination and curricular restructuring as well as significant changes to clinical attachments. With the available evid...
32,754,600
Front Cell Dev Biol
Transmission Routes Analysis of SARS-CoV-2: A Systematic Review and Case Report.
The global outbreak of SARS-CoV-2 spread rapidly throughout the world which transmitted among humans through various routes. Asymptomatic (carriers) and possible fecal-oral transmission, resulted into a large-scale spread. These issues pose great challenges to disease diagnosis and epidemic control. We obtained data on...
covid-19;sars-cov-2;asymptomatic patients;eyes-oral transmission;transmission routes
Journal Article
Li, Huanjie;Wang, Yangyang;Ji, Mingyu;Pei, Fengyan;Zhao, Qianqian;Zhou, Yunying;Hong, Yatian;Han, Shuyi;Wang, Jun;Wang, Qingxi;Li, Qiang;Wang, Yunshan
10.3389/fcell.2020.00618
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Transmission Routes Analysis of SARS-CoV-2: A Systematic Review and Case Report. [Abstract]: The global outbreak of SARS-CoV-2 spread rapidly throughout the world which transmitted among humans through various routes. Asymptomatic (carriers) and possible fecal-oral transmission, resulted into a large-scale spr...
32,771,634
Int J Infect Dis
Diagnostic serial interval as a novel indicator for contact tracing effectiveness exemplified with the SARS-CoV-2/COVID-19 outbreak in South Korea.
BACKGROUND: The clinical onset serial interval is often used as a proxy for the transmission interval of an infectious disease. For SARS-CoV-2/COVID-19, data on clinical onset serial intervals is limited, since symptom onset dates are not routinely recorded and do not exist in asymptomatic carriers. METHODS: We define ...
covid-19;clinical onset serial interval;contact tracing;diagnostic serial interval;serial interval;surveillance
Journal Article
Mettler, Sofia K;Kim, Jihoo;Maathuis, Marloes H
10.1016/j.ijid.2020.07.068
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: Diagnostic serial interval as a novel indicator for contact tracing effectiveness exemplified with the SARS-CoV-2/COVID-19 outbreak in South Korea. [Abstract]: BACKGROUND: The clinical onset serial interval is often used as a proxy for the transmission interval of an infectious disease. For SARS-CoV-2/COVID-19...
33,008,308
BMC Pregnancy Childbirth
Vaginal delivery in women with COVID-19: report of two cases.
BACKGROUND: During the ongoing global outbreak of COVID-19, pregnant women who are susceptible to COVID-19 should be highly concerned. The issue of vertical transmission and the possibility of neonatal infection is a major concern. CASE PRESENTATION: Case 1: A 35-year-old pregnant woman with a gestational age of 37 wee...
covid-19;case report;intrauterine vertical transmission;vaginal delivery
Case Reports;Journal Article
Cao, Dongmei;Chen, Miaomiao;Peng, Min;Yin, Heng;Sun, Guoqiang
10.1186/s12884-020-03281-4
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Vaginal delivery in women with COVID-19: report of two cases. [Abstract]: BACKGROUND: During the ongoing global outbreak of COVID-19, pregnant women who are susceptible to COVID-19 should be highly concerned. The issue of vertical transmission and the possibility of neonatal infection is a major concern. CASE ...
32,567,006
Eur J Nucl Med Mol Imaging
End-to-end automatic differentiation of the coronavirus disease 2019 (COVID-19) from viral pneumonia based on chest CT.
PURPOSE: In the absence of a virus nucleic acid real-time reverse transcriptase-polymerase chain reaction (RT-PCR) test and experienced radiologists, clinical diagnosis is challenging for viral pneumonia with clinical symptoms and CT signs similar to that of coronavirus disease 2019 (COVID-19). We developed an end-to-e...
artificial intelligence;bigbigan;coronavirus disease 2019 pneumonia;differentiation;semantic features
Journal Article;Multicenter Study;Research Support, Non-U.S. Gov't;Validation Study
Song, Jiangdian;Wang, Hongmei;Liu, Yuchan;Wu, Wenqing;Dai, Gang;Wu, Zongshan;Zhu, Puhe;Zhang, Wei;Yeom, Kristen W;Deng, Kexue
10.1007/s00259-020-04929-1
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: End-to-end automatic differentiation of the coronavirus disease 2019 (COVID-19) from viral pneumonia based on chest CT. [Abstract]: PURPOSE: In the absence of a virus nucleic acid real-time reverse transcriptase-polymerase chain reaction (RT-PCR) test and experienced radiologists, clinical diagnosis is challen...
32,522,870
Proc Natl Acad Sci U S A
Rationing social contact during the COVID-19 pandemic: Transmission risk and social benefits of US locations.
To prevent the spread of coronavirus disease 2019 (COVID-19), some types of public spaces have been shut down while others remain open. These decisions constitute a judgment about the relative danger and benefits of those locations. Using mobility data from a large sample of smartphones, nationally representative consu...
covid-19;social contact;social welfare;transmission risk
Journal Article;Research Support, Non-U.S. Gov't
Benzell, Seth G;Collis, Avinash;Nicolaides, Christos
10.1073/pnas.2008025117
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Rationing social contact during the COVID-19 pandemic: Transmission risk and social benefits of US locations. [Abstract]: To prevent the spread of coronavirus disease 2019 (COVID-19), some types of public spaces have been shut down while others remain open. These decisions constitute a judgment about the relat...
32,685,124
Iran J Microbiol
Tests with proven value in diagnosis of COVID-19.
COVID-19 has literally ravaged the entire world. People from all walks of life are badly affected because of compulsory lockdown around the world. Timely diagnosis is a problem as there is no single test that can achieve the highest acceptable sensitivity. Some of the tests are indeed costly and footing the bill by the...
covid-19;diagnostic tests;lockdown
Journal Article
Khan, Zahid Hussain;Samadi, Shahram;Makarem, Jalil;Mireskandari, Seyed Mohamad
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: Tests with proven value in diagnosis of COVID-19. [Abstract]: COVID-19 has literally ravaged the entire world. People from all walks of life are badly affected because of compulsory lockdown around the world. Timely diagnosis is a problem as there is no single test that can achieve the highest acceptable sensi...
32,399,092
Eur J Integr Med
Antimicrobial resistance is a global problem - a UK perspective.
Increasingly we are reaching a situation where current antimicrobial medicines are no longer effective for common infections, and antimicrobial resistance (AMR) is now a global public health crisis. The reliance on antimicrobials such as antibiotics has become a major issue for both medicine and agriculture, particular...
antibiotics;antimicrobial resistance;global health;government response;herbal medicine;infection
Journal Article
Hu, Xiao-Yang;Logue, Martin;Robinson, Nicola
10.1016/j.eujim.2020.101136
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Antimicrobial resistance is a global problem - a UK perspective. [Abstract]: Increasingly we are reaching a situation where current antimicrobial medicines are no longer effective for common infections, and antimicrobial resistance (AMR) is now a global public health crisis. The reliance on antimicrobials such...
32,841,316
Clin Infect Dis
Concomitant marked decline in prevalence of SARS-CoV-2 and other respiratory viruses among symptomatic patients following public health interventions in Australia: data from St Vincent's Hospital and associated screening clinics, Sydney, NSW.
Our Australian hospital tested almost 22,000 symptomatic people over 11 weeks for SARS-CoV-2 in a multiplex PCR assay. Following travel bans and physical distancing, SARS-CoV-2 and other respiratory viruses diagnoses fell dramatically. Increasing rhinovirus diagnoses as social control measures were relaxed may indirect...
covid-19;sars cov-2;influenza;public health;screening
Journal Article
Marriott, Deborah;Beresford, Rohan;Mirdad, Feras;Stark, Damien;Glanville, Allan;Chapman, Scott;Harkness, Jock;Dore, Gregory J;Andresen, David;Matthews, Gail V
10.1093/cid/ciaa1256
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: Concomitant marked decline in prevalence of SARS-CoV-2 and other respiratory viruses among symptomatic patients following public health interventions in Australia: data from St Vincent's Hospital and associated screening clinics, Sydney, NSW. [Abstract]: Our Australian hospital tested almost 22,000 symptomatic...
32,405,158
Clin Oncol (R Coll Radiol)
Reduced Fractionation in Lung Cancer Patients Treated with Curative-intent Radiotherapy during the COVID-19 Pandemic.
Patients treated with curative-intent lung radiotherapy are in the group at highest risk of severe complications and death from COVID-19. There is therefore an urgent need to reduce the risks associated with multiple hospital visits and their anti-cancer treatment. One recommendation is to consider alternative dose-fra...
covid-19;fractionation;lung cancer;radiotherapy
Journal Article
Faivre-Finn, C;Fenwick, J D;Franks, K N;Harrow, S;Hatton, M Q F;Hiley, C;McAleese, J J;McDonald, F;O'Hare, J;Peedell, C;Pope, T;Powell, C;Rulach, R;Toy, E
10.1016/j.clon.2020.05.001
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Reduced Fractionation in Lung Cancer Patients Treated with Curative-intent Radiotherapy during the COVID-19 Pandemic. [Abstract]: Patients treated with curative-intent lung radiotherapy are in the group at highest risk of severe complications and death from COVID-19. There is therefore an urgent need to reduce...
32,794,461
J Infect Dev Ctries
Missed takes towards a pandemic of COVID-19? A systematic literature review of Coronavirus related diseases in Pakistan.
Pakistan is also seeing the profound effect of the outbreak of COVID-19, which demands an urgent investigation of literature and further scientific investigation for cure and prevention. This study has employed the systematic approach for searching the literature from the recently compiled database of researches namely...
covid-19;coronavirus;mers-cov;pakistan;sars
Journal Article;Systematic Review
Haq, Wajiha;Raza, Syed Hassan;Malik, Muhammad Wasif
10.3855/jidc.12771
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Missed takes towards a pandemic of COVID-19? A systematic literature review of Coronavirus related diseases in Pakistan. [Abstract]: Pakistan is also seeing the profound effect of the outbreak of COVID-19, which demands an urgent investigation of literature and further scientific investigation for cure and pre...
32,659,462
Thromb Res
Coronavirus disease 2019 (COVID-19) associated coagulopathy and its impact on outcomes in Shenzhen, China: A retrospective cohort study.
BACKGROUND: Early detection of suspected critical patients infected with coronavirus disease 2019 (COVID-19) is very important for the treatment of patients. This study aimed to investigate the role of COVID-19 associated coagulopathy (CAC) to preview and triage. METHODS AND RESULTS: A cohort study was designed from go...
coagulopathy;coronavirus disease 2019;isth score;mechanical ventilation;outcome
Journal Article
Luan, Ying-Yi;Liu, Yan;Liu, Xue-Yan;Yu, Bao-Jun;Chen, Rong-Ling;Peng, Mian;Ren, Di;Li, Hao-Li;Huang, Lei;Liu, Yong;Li, Jin-Xiu;Feng, Yong-Wen;Wu, Ming
10.1016/j.thromres.2020.07.015
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Coronavirus disease 2019 (COVID-19) associated coagulopathy and its impact on outcomes in Shenzhen, China: A retrospective cohort study. [Abstract]: BACKGROUND: Early detection of suspected critical patients infected with coronavirus disease 2019 (COVID-19) is very important for the treatment of patients. This...
32,313,784
Cureus
Changes in Subway Ridership in Response to COVID-19 in Seoul, South Korea: Implications for Social Distancing.
Introduction While numerous episodes of Coronavirus disease 2019 (COVID-19) infection and subsequent government announcements in South Korea were accompanied by widespread social distancing efforts by the people, it is unclear whether these episodes and government announcements were actually influential in improving so...
covid-19;public transport;risk perception;social distancing;south korea
Journal Article
Park, Jewel
10.7759/cureus.7668
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Changes in Subway Ridership in Response to COVID-19 in Seoul, South Korea: Implications for Social Distancing. [Abstract]: Introduction While numerous episodes of Coronavirus disease 2019 (COVID-19) infection and subsequent government announcements in South Korea were accompanied by widespread social distancin...
32,695,323
Clin Kidney J
SARS-CoV-2 infection in dialysis patients in northern Italy: a single-centre experience.
Background: Dialysis patients are considered at high risk for COVID-19 and the infection can easily spread in dialysis units. Methods: We conducted an observational single-centre cohort study to describe clinical characteristics, treatments and outcomes of dialysis patients with severe acute respiratory syndrome corona...
covid-19;sars-cov-2;dialysis
Journal Article
Fontana, Francesco;Giaroni, Francesco;Frisina, Monica;Alfano, Gaetano;Mori, Giacomo;Lucchi, Leonardo;Magistroni, Riccardo;Cappelli, Gianni
10.1093/ckj/sfaa084
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: SARS-CoV-2 infection in dialysis patients in northern Italy: a single-centre experience. [Abstract]: Background: Dialysis patients are considered at high risk for COVID-19 and the infection can easily spread in dialysis units. Methods: We conducted an observational single-centre cohort study to describe clinic...
32,834,798
Appl Soft Comput
Forecasting of COVID19 per regions using ARIMA models and polynomial functions.
COVID-2019 is a global threat, for this reason around the world, researches have been focused on topics such as to detect it, prevent it, cure it, and predict it. Different analyses propose models to predict the evolution of this epidemic. These analyses propose models for specific geographical areas, specific countrie...
arima model;covid-19 epidemic;forecast;geographic region
Journal Article
Hernandez-Matamoros, Andres;Fujita, Hamido;Hayashi, Toshitaka;Perez-Meana, Hector
10.1016/j.asoc.2020.106610
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: Forecasting of COVID19 per regions using ARIMA models and polynomial functions. [Abstract]: COVID-2019 is a global threat, for this reason around the world, researches have been focused on topics such as to detect it, prevent it, cure it, and predict it. Different analyses propose models to predict the evoluti...
32,838,801
J Med Case Rep
Adrenal insufficiency in coronavirus disease 2019: a case report.
BACKGROUND: Novel coronavirus disease 2019 presents with fever, dry cough, fatigue, and shortness of breath in most cases; however, some rare manifestations in other organs have also been reported so far. CASE PRESENTATION: Here, the case of a 69-year-old Iranian man with coronavirus disease 2019 is presented who suffe...
2019-ncov;adrenal insufficiency;covid-19;case report;sars-cov-2
Case Reports;Journal Article
Heidarpour, Maryam;Vakhshoori, Mehrbod;Abbasi, Saeed;Shafie, Davood;Rezaei, Nima
10.1186/s13256-020-02461-2
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Adrenal insufficiency in coronavirus disease 2019: a case report. [Abstract]: BACKGROUND: Novel coronavirus disease 2019 presents with fever, dry cough, fatigue, and shortness of breath in most cases; however, some rare manifestations in other organs have also been reported so far. CASE PRESENTATION: Here, the...
32,480,361
JMIR Mhealth Uhealth
Development and Clinical Evaluation of a Web-Based Upper Limb Home Rehabilitation System Using a Smartwatch and Machine Learning Model for Chronic Stroke Survivors: Prospective Comparative Study.
BACKGROUND: Recent advancements in wearable sensor technology have shown the feasibility of remote physical therapy at home. In particular, the current COVID-19 pandemic has revealed the need and opportunity of internet-based wearable technology in future health care systems. Previous research has shown the feasibility...
artificial intelligence;chronic stroke;home-based rehabilitation;machine learning;smartwatch;wearable device
Comparative Study;Controlled Clinical Trial;Journal Article;Research Support, Non-U.S. Gov't
Chae, Sang Hoon;Kim, Yushin;Lee, Kyoung-Soub;Park, Hyung-Soon
10.2196/17216
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Development and Clinical Evaluation of a Web-Based Upper Limb Home Rehabilitation System Using a Smartwatch and Machine Learning Model for Chronic Stroke Survivors: Prospective Comparative Study. [Abstract]: BACKGROUND: Recent advancements in wearable sensor technology have shown the feasibility of remote phys...
32,639,077
Dermatol Ther
Cutaneous manifestations and considerations in COVID-19 pandemic: A systematic review.
COVID-19 had a great impact on medical approaches among dermatologist. This systematic review focuses on all skin problems related to COVID-19, including primary and secondary COVID-related cutaneous presentations and the experts recommendations about dermatological managements especially immunomodulators usage issues....
covid-19;alopecia;biologic;collagen vascular disorder;corona virus;cosmetic procedure;cutaneous;cutaneous manifestation;dermatitis;dermatology;drug reaction;eczema;health care staff;hidradenitis suppurativa;immunobullous;immunomodulator;immunosupressant;immunosupressive;novel human coronavirus (sars-cov-2);pandemic con...
Journal Article;Systematic Review
Seirafianpour, Farnoosh;Sodagar, Sogand;Pour Mohammad, Arash;Panahi, Parsa;Mozafarpoor, Samaneh;Almasi, Simin;Goodarzi, Azadeh
10.1111/dth.13986
[ 1, 1, 1, 0, 0, 0, 0 ]
[Title]: Cutaneous manifestations and considerations in COVID-19 pandemic: A systematic review. [Abstract]: COVID-19 had a great impact on medical approaches among dermatologist. This systematic review focuses on all skin problems related to COVID-19, including primary and secondary COVID-related cutaneous presentation...
32,653,530
Pharmacol Ther
Good or bad: Application of RAAS inhibitors in COVID-19 patients with cardiovascular comorbidities.
The coronavirus disease 2019 (COVID-19) pandemic is caused by a newly emerged coronavirus (CoV) called Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2). COVID-19 patients with cardiovascular disease (CVD) comorbidities have significantly increased morbidity and mortality. The use of angiotensin-converting e...
bradykinin;covid-19;hypertension;inflammation;raas inhibitors
Journal Article;Research Support, N.I.H., Intramural;Research Support, Non-U.S. Gov't;Review
Wang, James Jiqi;Edin, Matthew L;Zeldin, Darryl C;Li, Chenze;Wang, Dao Wen;Chen, Chen
10.1016/j.pharmthera.2020.107628
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Good or bad: Application of RAAS inhibitors in COVID-19 patients with cardiovascular comorbidities. [Abstract]: The coronavirus disease 2019 (COVID-19) pandemic is caused by a newly emerged coronavirus (CoV) called Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2). COVID-19 patients with cardiovascu...
32,384,398
Pediatr Infect Dis J
COVID-19 in Neonates and Infants: Progression and Recovery.
Between March 10, 2020 and April 17, 2020, of 8/70 (11.4%) SARS-CoV-2 positive infants that presented, 5/8 (63%) developed fever, 4/8 (50%) had lower respiratory tract involvement, 2/8 (25%) had neutropenia and thrombocytosis, and 4/8 infants (50%) were treated for suspected sepsis with broad-spectrum antibiotics. Only...
Journal Article
Ng, Khuen Foong;Bandi, Srini;Bird, Paul William;Wei-Tze Tang, Julian
10.1097/INF.0000000000002738
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: COVID-19 in Neonates and Infants: Progression and Recovery. [Abstract]: Between March 10, 2020 and April 17, 2020, of 8/70 (11.4%) SARS-CoV-2 positive infants that presented, 5/8 (63%) developed fever, 4/8 (50%) had lower respiratory tract involvement, 2/8 (25%) had neutropenia and thrombocytosis, and 4/8 infa...
32,695,025
Front Physiol
Regulatory Cross Talk Between SARS-CoV-2 Receptor Binding and Replication Machinery in the Human Host.
We dissect the mechanism of SARS-CoV-2 in human lung host from the initial phase of receptor binding to viral replication machinery. Two independent lung protein interactome were constructed to reveal the signaling process on receptor activation and host protein hijacking machinery in the pathogenesis of virus. Further...
covid-19;sars-cov-2;host mechanism;mirna targets;systems biology;transcriptome
Journal Article
Ahmed, Shiek S S J;Paramasivam, Prabu;Raj, Kamal;Kumar, Vishal;Murugesan, Ram;Ramakrishnan, V
10.3389/fphys.2020.00802
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Regulatory Cross Talk Between SARS-CoV-2 Receptor Binding and Replication Machinery in the Human Host. [Abstract]: We dissect the mechanism of SARS-CoV-2 in human lung host from the initial phase of receptor binding to viral replication machinery. Two independent lung protein interactome were constructed to re...
32,241,056
Zhonghua Wai Ke Za Zhi
[Suggestions for thoracic surgery clinical practice in non-epidemic area of 2019 coronavirus disease].
In this paper, the mechanism of destroying human alveolar epithelial cells and pulmonary tissue by 2019 novel coronavirus (2019-nCoV) was discussed firstly. There may be multiple mechanisms including killing directly the target cells and hyperinflammatory responses. Secondly, the clinical features, CT imaging, short-te...
2019 coronavirus disease;coronavirus infection;lung injury;non-epidemic area;novel coronavirus pneumonia;respiratory function tests;thoracic surgery;work suggestion
Journal Article
Dai, F Q;Guo, W;Deng, B;Tao, S L;Jiang, B;Wang, Y J;Cheng, N;Wu, X L;Wang, Z H;Bao, T;Tan, Q Y
10.3760/cma.j.cn112139-20200219-00100
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: [Suggestions for thoracic surgery clinical practice in non-epidemic area of 2019 coronavirus disease]. [Abstract]: In this paper, the mechanism of destroying human alveolar epithelial cells and pulmonary tissue by 2019 novel coronavirus (2019-nCoV) was discussed firstly. There may be multiple mechanisms includ...
32,697,645
Br J Nurs
The return-to-work conundrum.
Sam Foster, Chief Nurse, Oxford University Hospitals, describes the problems faced by trusts as they attempt to limit the risks faced by employees returning to the workplace as the coronavirus lockdown eases.
Journal Article
Foster, Sam
10.12968/bjon.2020.29.14.839
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The return-to-work conundrum. [Abstract]: Sam Foster, Chief Nurse, Oxford University Hospitals, describes the problems faced by trusts as they attempt to limit the risks faced by employees returning to the workplace as the coronavirus lockdown eases. [Keywords]:
32,779,964
Otolaryngol Head Neck Surg
Droplet and Aerosol Generation With Endonasal Surgery: Methods to Mitigate Risk During the COVID-19 Pandemic.
OBJECTIVE: To define the aerosol and droplet risks associated with endonasal drilling and to identify mitigation strategies. STUDY DESIGN: Simulation series with fluorescent 3-dimensional (3D) printed sinonasal models and deidentified cadaveric heads. SETTINGS: Dedicated surgical laboratory. SUBJECTS AND METHODS: Cadav...
covid-19;aerosol;droplet;endonasal;prevention;safety;skull base
Journal Article
Dharmarajan, Harish;Freiser, Monika E;Sim, Edward;Boorgu, Devi Sai Sri Kavya;Corcoran, Timothy E;Wang, Eric W;Gardner, Paul A;Snyderman, Carl H
10.1177/0194599820949802
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Droplet and Aerosol Generation With Endonasal Surgery: Methods to Mitigate Risk During the COVID-19 Pandemic. [Abstract]: OBJECTIVE: To define the aerosol and droplet risks associated with endonasal drilling and to identify mitigation strategies. STUDY DESIGN: Simulation series with fluorescent 3-dimensional (...
32,768,223
Vet Microbiol
Coronaviruses in cats and other companion animals: Where does SARS-CoV-2/COVID-19 fit?
Coronaviruses (CoVs) cause disease in a range of agricultural and companion animal species, and can be important causes of zoonotic infections. In humans, several coronaviruses circulate seasonally. Recently, a novel zoonotic CoV named SARS-CoV-2 emerged from a bat reservoir, resulting in the COVID-19 pandemic. With a ...
ace-2;coronavirus;feline coronavirus;sars-cov-2
Journal Article;Review
Stout, Alison E;Andre, Nicole M;Jaimes, Javier A;Millet, Jean K;Whittaker, Gary R
10.1016/j.vetmic.2020.108777
[ 0, 0, 0, 1, 1, 0, 0 ]
[Title]: Coronaviruses in cats and other companion animals: Where does SARS-CoV-2/COVID-19 fit? [Abstract]: Coronaviruses (CoVs) cause disease in a range of agricultural and companion animal species, and can be important causes of zoonotic infections. In humans, several coronaviruses circulate seasonally. Recently, a n...
32,383,183
J Med Virol
A comparison study of SARS-CoV-2 IgG antibody between male and female COVID-19 patients: A possible reason underlying different outcome between sex.
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in China at the end of 2019 has spread throughout the world and caused many thousands of deaths. The previous study reported a higher severe status rate and mortality rate in male patients in China. However, the reason underlying this differe...
covid-19 patients;sars-cov-2 igg antibody;sexual discrepancy
Comparative Study;Journal Article
Zeng, Fanfan;Dai, Chan;Cai, Pengcheng;Wang, Jinbiao;Xu, Lei;Li, Jianyu;Hu, Guoyun;Wang, Zheng;Zheng, Fang;Wang, Lin
10.1002/jmv.25989
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: A comparison study of SARS-CoV-2 IgG antibody between male and female COVID-19 patients: A possible reason underlying different outcome between sex. [Abstract]: The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in China at the end of 2019 has spread throughout the world and caused m...
32,978,920
J Assoc Physicians India
Preliminary Observations and Experiences of Physiotherapy Practice in Acute Care Setup of COVID 19: A Retrospective Observational Study.
Background: The rapid outbreak of coronavirus disease 2019 (COVID-19), a public health emergency of grave concern, warranted hospital admissions with almost 90,000 cases in June 2020 in city of Mumbai. 3-10% of the patients with moderate to severe involvement required intensive care unit (ICU) admission with respirator...
Journal Article;Observational Study
Jiandani, Mariya P;Salagre, Santosh B;Kazi, Shabana;Iyer, Saraswati;Patil, Poonam;Khot, Wasim Y;Patil, Ekta;Sopariwala, Mashira
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Preliminary Observations and Experiences of Physiotherapy Practice in Acute Care Setup of COVID 19: A Retrospective Observational Study. [Abstract]: Background: The rapid outbreak of coronavirus disease 2019 (COVID-19), a public health emergency of grave concern, warranted hospital admissions with almost 90,00...
32,621,237
Eur Radiol
Radiomics nomogram for the prediction of 2019 novel coronavirus pneumonia caused by SARS-CoV-2.
OBJECTIVES: To develop and validate a radiomics model for predicting 2019 novel coronavirus (COVID-19) pneumonia. METHODS: For this retrospective study, a radiomics model was developed on the basis of a training set consisting of 136 patients with COVID-19 pneumonia and 103 patients with other types of viral pneumonia....
coronavirus infections;pneumonia, viral;radiomics, nomograms;thorax;tomography, x-ray computed
Journal Article
Fang, Xu;Li, Xiao;Bian, Yun;Ji, Xiang;Lu, Jianping
10.1007/s00330-020-07032-z
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Radiomics nomogram for the prediction of 2019 novel coronavirus pneumonia caused by SARS-CoV-2. [Abstract]: OBJECTIVES: To develop and validate a radiomics model for predicting 2019 novel coronavirus (COVID-19) pneumonia. METHODS: For this retrospective study, a radiomics model was developed on the basis of a ...
32,538,935
JNMA J Nepal Med Assoc
COVID 19 and Nepal: Identification of Critical Public Health Measures.
The COVID-19 pandemic is unfolding at an unprecedented pace. The unprecedented threat provides an opportunity to emerge with robust health systems. Nepal has implemented several containment measures such as Rapid Response Team formulation; testing; isolation; quarantine; contact tracing;surveillance, establishment of C...
covid-19; nepal; world health organization.
Journal Article
Neupane, Harish Chandra;Shrestha, Niki;Adhikari, Shital;Gauli, Basanta
10.31729/jnma.4950
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID 19 and Nepal: Identification of Critical Public Health Measures. [Abstract]: The COVID-19 pandemic is unfolding at an unprecedented pace. The unprecedented threat provides an opportunity to emerge with robust health systems. Nepal has implemented several containment measures such as Rapid Response Team f...
33,075,740
Diabetes Metab Syndr
Decentralized COVID-19 measures in Brazil were ineffective to protect people with diabetes.
BACKGROUND AND AIMS: COVID-19 severity and mortality are elevated in individuals with diabetes. During the pandemic, interventions recommended globally for people with diabetes were to keep blood glucose on target whilst staying at home to curb the spread of the virus. In Brazil, similar measures were proposed. The aim...
brazil;covid-19;coronavirus;diabetes;pandemic;sars-cov-2
Journal Article
Ugliara Barone, Mark Thomaz;Harnik, Simone Bega;Chaluppe, Matheus;Vieira de Luca, Patricia;Ngongo, Belinda;Pedrosa, Hermelinda Cordeiro;Pirolo, Vanessa;Franco, Denise Reis;Malta, Deborah Carvalho;Giampaoli, Viviana
10.1016/j.dsx.2020.10.005
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Decentralized COVID-19 measures in Brazil were ineffective to protect people with diabetes. [Abstract]: BACKGROUND AND AIMS: COVID-19 severity and mortality are elevated in individuals with diabetes. During the pandemic, interventions recommended globally for people with diabetes were to keep blood glucose on ...
32,834,832
Nano Today
Covid-19 acute responses and possible long term consequences: What nanotoxicology can teach us.
Long-term effects of Covid-19 disease are still poorly understood. However, similarities between the responses to SARS-CoV-2 and certain nanomaterials suggest fibrotic pulmonary disease as a concern for public health in the next future. Cross-talk between nanotoxicology and other relevant disciplines can help us to dep...
covid-19;coronavirus;fibrosis;nanotoxicology;sars-cov-2;virus-host interaction
Journal Article
Kinaret, Pia A S;Del Giudice, Giusy;Greco, Dario
10.1016/j.nantod.2020.100945
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Covid-19 acute responses and possible long term consequences: What nanotoxicology can teach us. [Abstract]: Long-term effects of Covid-19 disease are still poorly understood. However, similarities between the responses to SARS-CoV-2 and certain nanomaterials suggest fibrotic pulmonary disease as a concern for ...
32,482,977
J Orthop Trauma
Hip Fracture Outcomes During the COVID-19 Pandemic: Early Results From New York.
OBJECTIVE: To evaluate inpatient outcomes among patients with hip fracture treated during the COVID-19 pandemic in New York City. DESIGN: Multicenter retrospective cohort study. SETTING: One Level 1 trauma center and one orthopaedic specialty hospital in New York City. PATIENTS/PARTICIPANTS: Fifty-nine consecutive pati...
Evaluation Study;Journal Article;Multicenter Study
LeBrun, Drake G;Konnaris, Maxwell A;Ghahramani, Gregory C;Premkumar, Ajay;DeFrancesco, Chris J;Gruskay, Jordan A;Dvorzhinskiy, Aleksey;Sandhu, Milan S;Goldwyn, Elan M;Mendias, Christopher L;Ricci, William M
10.1097/BOT.0000000000001849
[ 1, 1, 1, 0, 0, 0, 0 ]
[Title]: Hip Fracture Outcomes During the COVID-19 Pandemic: Early Results From New York. [Abstract]: OBJECTIVE: To evaluate inpatient outcomes among patients with hip fracture treated during the COVID-19 pandemic in New York City. DESIGN: Multicenter retrospective cohort study. SETTING: One Level 1 trauma center and o...
32,241,244
Emerg Microbes Infect
Diagnostic value and key features of computed tomography in Coronavirus Disease 2019.
On 31 December 2019, a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, Hubei province, China, and caused the outbreak of the Coronavirus Disease 2019 (COVID-19). To date, computed tomography (CT) findings have been recommended as major evidence for the clinical diagnosis of COVID-19 in Hu...
coronavirus disease 2019;sars-cov-2;computed tomography;diagnosis;ground-glass opacity
Journal Article;Review
Li, Bingjie;Li, Xin;Wang, Yaxuan;Han, Yikai;Wang, Yidi;Wang, Chen;Zhang, Guorui;Jin, Jianjun;Jia, Hongxia;Fan, Feifei;Ma, Wang;Liu, Hong;Zhou, Yue
10.1080/22221751.2020.1750307
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Diagnostic value and key features of computed tomography in Coronavirus Disease 2019. [Abstract]: On 31 December 2019, a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, Hubei province, China, and caused the outbreak of the Coronavirus Disease 2019 (COVID-19). To date, computed to...
32,653,628
Public Health
An approximation-based approach for periodic estimation of effective reproduction number: a tool for decision-making in the context of coronavirus disease 2019 (COVID-19) outbreak.
OBJECTIVES: The effective reproduction number (R) is a more practical epidemiological parameter than basic reproduction number (R0) for characterization of infectious disease epidemics as it takes into account presence of immune individuals in the population which R0 does not. Periodic assessment of R can inform public...
covid-19;effective reproduction number;india;public health intervention
Journal Article
Das, A
10.1016/j.puhe.2020.06.047
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: An approximation-based approach for periodic estimation of effective reproduction number: a tool for decision-making in the context of coronavirus disease 2019 (COVID-19) outbreak. [Abstract]: OBJECTIVES: The effective reproduction number (R) is a more practical epidemiological parameter than basic reproductio...
32,876,019
Chirurgia (Bucur)
The Challenge of COVID-19: The Biological Characteristics and Outcomes in a Series of 130 Breast Cancer Patients Operated on During the Pandemic.
Background: The worldwide outbreak of the 2019 novel coronavirus disease (COVID-19) emerged in Wuhan, China close to the end of 2019. We analyse the clinical characteristics and management outcomes of a small group of patients who have been treated in the early stage of the COVID-19 disease, and discuss the impact of t...
ace2;covid-19;mers-cov;sars-cov;sars-cov2;breastcancer
Journal Article
Abdalla, Abdalla Saad;Asaad, Amira;Fisher, Rebecca;Clayton, Gill;Syed, Abdul;Barron, Marina;Idaewor, Philip;Salih, Ali;Elamass, Mohamed;Aladili, Zina;Menon, Jay;Uddin, Aaliya;Gee, Hilary;Bonner, Denise;Merron, Helen;Duncombe, Karen;Campaner, Gabriel;Alkistawi, Firas;Targett, John;Eleti, Sudhakar Reddy;Comez, Turhan;Smi...
10.21614/chirurgia.115.4.458
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The Challenge of COVID-19: The Biological Characteristics and Outcomes in a Series of 130 Breast Cancer Patients Operated on During the Pandemic. [Abstract]: Background: The worldwide outbreak of the 2019 novel coronavirus disease (COVID-19) emerged in Wuhan, China close to the end of 2019. We analyse the clin...
32,967,854
Br J Sports Med
Return to sport for North American professional sport leagues in the context of COVID-19.
COVID-19 is a respiratory illness that can spread from person to person. A range of clinical scenarios exist, from an asymptomatic disease course to SARS and death. This document describes important considerations for 5 North American professional sports leagues (Major League Baseball, Major League Soccer, National Bas...
health;sporting organisation
Journal Article;Review
DiFiori, John P;Green, Gary;Meeuwisse, Willem;Putukian, Margot;Solomon, Gary S;Sills, Allen
10.1136/bjsports-2020-103227
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Return to sport for North American professional sport leagues in the context of COVID-19. [Abstract]: COVID-19 is a respiratory illness that can spread from person to person. A range of clinical scenarios exist, from an asymptomatic disease course to SARS and death. This document describes important considerat...
32,425,268
Gynecol Oncol
Wait-time for hysterectomy and survival of women with early-stage cervical cancer: A clinical implication during the coronavirus pandemic.
OBJECTIVE: A global pandemic caused by a novel coronavirus (Covid-19) has created unique challenges to providing timely care for cancer patients. In early-stage cervical cancer, postponing hysterectomy for 6-8 weeks is suggested as a possible option in the Covid-19 burdened hospitals. Yet, literature examining the impa...
cervical cancer;early stage;hysterectomy;surgery;survival;wait time
Journal Article;Observational Study;Research Support, Non-U.S. Gov't
Matsuo, Koji;Novatt, Hilary;Matsuzaki, Shinya;Hom, Marianne S;Castaneda, Antonio V;Licon, Ernesto;Nusbaum, David J;Roman, Lynda D
10.1016/j.ygyno.2020.05.019
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Wait-time for hysterectomy and survival of women with early-stage cervical cancer: A clinical implication during the coronavirus pandemic. [Abstract]: OBJECTIVE: A global pandemic caused by a novel coronavirus (Covid-19) has created unique challenges to providing timely care for cancer patients. In early-stage...
32,660,503
Global Health
Misinformation and de-contextualization: international media reporting on Sweden and COVID-19.
In the first month of the 2020 COVID-19 pandemic, Sweden took the same strategy as most other countries, working to "flatten the curve," by slowing transmission so that the healthcare system could cope with the disease. However, unlike most other countries, much of Sweden's implementation focused on voluntary and stepw...
covid-19;news;pandemic;policy evaluation;social media;sweden
Journal Article;Research Support, Non-U.S. Gov't
Irwin, Rachel Elisabeth
10.1186/s12992-020-00588-x
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Misinformation and de-contextualization: international media reporting on Sweden and COVID-19. [Abstract]: In the first month of the 2020 COVID-19 pandemic, Sweden took the same strategy as most other countries, working to "flatten the curve," by slowing transmission so that the healthcare system could cope wi...
32,624,655
Ann Gastroenterol
Gastrointestinal involvement in COVID-19: a systematic review and meta-analysis.
Background: Patients with COVID-19 usually manifest fever and respiratory symptoms. However, some patients also experience gastrointestinal (GI) symptoms such as diarrhea, vomiting and abdominal pain. In addition, SARS-CoV-2 RNA has been detected in feces of infected patients. Currently there is huge evolving research ...
covid-19;gi symptoms;sars-cov-2;abdominal pain;diarrhea;meta-analysis;nausea;stool sars-cov-2 rna;systematic review;vomiting
Journal Article
Rokkas, Theodore
10.20524/aog.2020.0506
[ 0, 1, 0, 0, 1, 0, 0 ]
[Title]: Gastrointestinal involvement in COVID-19: a systematic review and meta-analysis. [Abstract]: Background: Patients with COVID-19 usually manifest fever and respiratory symptoms. However, some patients also experience gastrointestinal (GI) symptoms such as diarrhea, vomiting and abdominal pain. In addition, SARS...
32,795,832
Med Hypotheses
Mitochondrial-targeted ubiquinone: A potential treatment for COVID-19.
Immune dysregulation characterized by T cell exhaustion and high level of inflammatory cytokines is associated with severe COVID-19. Figuring out the early event of immune dysregulation would provide a potential treatment for COVID-19. Recent evidence indicate that mitochondrial dysfunction participates in the developm...
covid-19;mitoq;mitochondrial dysfunction;sars-cov-2;t cell exhaustion
Journal Article
Ouyang, Lichen;Gong, Jie
10.1016/j.mehy.2020.110161
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Mitochondrial-targeted ubiquinone: A potential treatment for COVID-19. [Abstract]: Immune dysregulation characterized by T cell exhaustion and high level of inflammatory cytokines is associated with severe COVID-19. Figuring out the early event of immune dysregulation would provide a potential treatment for CO...
32,422,320
J Mol Cell Cardiol
p38 MAPK inhibition: A promising therapeutic approach for COVID-19.
COVID-19, caused by the SARS-CoV-2 virus, is a major source of morbidity and mortality due to its inflammatory effects in the lungs and heart. The p38 MAPK pathway plays a crucial role in the release of pro-inflammatory cytokines such as IL-6 and has been implicated in acute lung injury and myocardial dysfunction. The ...
ace2;covid-19;sars-cov-2;p38 mapk
Journal Article
Grimes, Joseph M;Grimes, Kevin V
10.1016/j.yjmcc.2020.05.007
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: p38 MAPK inhibition: A promising therapeutic approach for COVID-19. [Abstract]: COVID-19, caused by the SARS-CoV-2 virus, is a major source of morbidity and mortality due to its inflammatory effects in the lungs and heart. The p38 MAPK pathway plays a crucial role in the release of pro-inflammatory cytokines s...
32,224,116
J Microbiol Immunol Infect
Do children need a longer time to shed SARS-CoV-2 in stool than adults?
SARS-CoV-2 can be shed in the stool of patients in the recovery phase. Children show a longer shedding time than adults. We analyzed the possible causes of this finding and recommend that a negative stool sample be included in a patient's discharge criteria.
Journal Article
Ma, Xiang;Su, Liang;Zhang, Yunkui;Zhang, Xiuzhen;Gai, Zhongtao;Zhang, Zhongfa
10.1016/j.jmii.2020.03.010
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Do children need a longer time to shed SARS-CoV-2 in stool than adults? [Abstract]: SARS-CoV-2 can be shed in the stool of patients in the recovery phase. Children show a longer shedding time than adults. We analyzed the possible causes of this finding and recommend that a negative stool sample be included in ...
32,471,856
Science
Introductions and early spread of SARS-CoV-2 in the New York City area.
New York City (NYC) has emerged as one of the epicenters of the current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. To identify the early transmission events underlying the rapid spread of the virus in the NYC metropolitan area, we sequenced the virus that causes coronavirus disease 2019 (COV...
Journal Article;Research Support, N.I.H., Extramural
Gonzalez-Reiche, Ana S;Hernandez, Matthew M;Sullivan, Mitchell J;Ciferri, Brianne;Alshammary, Hala;Obla, Ajay;Fabre, Shelcie;Kleiner, Giulio;Polanco, Jose;Khan, Zenab;Alburquerque, Bremy;van de Guchte, Adriana;Dutta, Jayeeta;Francoeur, Nancy;Melo, Betsaida Salom;Oussenko, Irina;Deikus, Gintaras;Soto, Juan;Sridhar, Shwe...
10.1126/science.abc1917
[ 0, 0, 1, 1, 1, 0, 0 ]
[Title]: Introductions and early spread of SARS-CoV-2 in the New York City area. [Abstract]: New York City (NYC) has emerged as one of the epicenters of the current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. To identify the early transmission events underlying the rapid spread of the virus i...
32,134,205
Pediatr Pulmonol
Clinical and CT features in pediatric patients with COVID-19 infection: Different points from adults.
PURPOSE: To discuss the different characteristics of clinical, laboratory, and chest computed tomography (CT) in pediatric patients from adults with 2019 novel coronavirus (COVID-19) infection. METHODS: The clinical, laboratory, and chest CT features of 20 pediatric inpatients with COVID-19 infection confirmed by phary...
covid-19;child;clinical features;infection;tomography
Journal Article
Xia, Wei;Shao, Jianbo;Guo, Yu;Peng, Xuehua;Li, Zhen;Hu, Daoyu
10.1002/ppul.24718
[ 0, 0, 0, 1, 1, 0, 0 ]
[Title]: Clinical and CT features in pediatric patients with COVID-19 infection: Different points from adults. [Abstract]: PURPOSE: To discuss the different characteristics of clinical, laboratory, and chest computed tomography (CT) in pediatric patients from adults with 2019 novel coronavirus (COVID-19) infection. MET...
32,925,503
Eur J Gastroenterol Hepatol
Primary presentation of COVID-19 solely with gastrointestinal symptoms: a problem for the containment of the disease.
An oligosymptomatic patient with initially exclusively gastrointestinal symptoms (massive nausea and mild pancreatitis) turned out to suffer from COVID-19 during the hospital stay. The patient did not exhibit the typical COVID-symptoms cough or fever despite lung involvement. The gastroenterological diagnostic investig...
Case Reports;Journal Article
Dietrich, Christoph G;Hubner, Dolores;Marx, Gernot;Bickenbach, Johannes;Bootsveld, Andreas
10.1097/MEG.0000000000001922
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Primary presentation of COVID-19 solely with gastrointestinal symptoms: a problem for the containment of the disease. [Abstract]: An oligosymptomatic patient with initially exclusively gastrointestinal symptoms (massive nausea and mild pancreatitis) turned out to suffer from COVID-19 during the hospital stay. ...
32,996,607
J Ultrasound Med
Comparison Between Lung Ultrasound and Computed Tomographic Findings in Patients With COVID-19 Pneumonia.
OBJECTIVES: The aim of this study was to describe findings from lung ultrasound (LUS) and computed tomography (CT) in health professionals with coronavirus disease 2019 pneumonia and to evaluate the associations of the findings of both tests. METHODS: This cross-sectional observational study evaluated 45 health profess...
covid-19;computed tomography;coronavirus disease 2019;lung ultrasound;pneumonia;severe acute respiratory syndrome coronavirus 2
Journal Article
Lopes, Agnaldo Jose;Mafort, Thiago Thomaz;da Costa, Claudia Henrique;Rufino, Rogerio;de Cassia Firmida, Monica;Kirk, Kennedy Martins;Cobo, Carolina Gianella;da Costa, Hanna da Silva Bessa;da Cruz, Carlos Miguel Brum Queiroz;Mogami, Roberto
10.1002/jum.15521
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Comparison Between Lung Ultrasound and Computed Tomographic Findings in Patients With COVID-19 Pneumonia. [Abstract]: OBJECTIVES: The aim of this study was to describe findings from lung ultrasound (LUS) and computed tomography (CT) in health professionals with coronavirus disease 2019 pneumonia and to evaluat...
33,068,880
Biosens Bioelectron
A computational simulation platform for designing real-time monitoring systems with application to COVID-19.
With the aim of contributing to the fight against the coronavirus disease 2019 (COVID-19), numerous strategies have been proposed. While developing an effective vaccine can take months up to years, detection of infected patients seems like one of the best ideas for controlling the situation. The role of biosensors in c...
biosensors;covid-19;computational fluid dynamics;microfluidics;sars-cov-2
Journal Article
Shahbazi, Fatemeh;Jabbari, Masoud;Esfahani, Mohammad Nasr;Keshmiri, Amir
10.1016/j.bios.2020.112716
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: A computational simulation platform for designing real-time monitoring systems with application to COVID-19. [Abstract]: With the aim of contributing to the fight against the coronavirus disease 2019 (COVID-19), numerous strategies have been proposed. While developing an effective vaccine can take months up to...