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32,838,342
Cell Rep Med
Systems-Level Immunomonitoring from Acute to Recovery Phase of Severe COVID-19.
Severe disease of SARS-CoV-2 is characterized by vigorous inflammatory responses in the lung, often with a sudden onset after 5-7 days of stable disease. Efforts to modulate this hyperinflammation and the associated acute respiratory distress syndrome rely on the unraveling of the immune cell interactions and cytokines...
covid-19;sars-cov-2;human immunology;mass cytometry;plasma proteins;systems immunology
Journal Article
Rodriguez, Lucie;Pekkarinen, Pirkka T;Lakshmikanth, Tadepally;Tan, Ziyang;Consiglio, Camila Rosat;Pou, Christian;Chen, Yang;Mugabo, Constantin Habimana;Nguyen, Ngoc Anh;Nowlan, Kirsten;Strandin, Tomas;Levanov, Lev;Mikes, Jaromir;Wang, Jun;Kantele, Anu;Hepojoki, Jussi;Vapalahti, Olli;Heinonen, Santtu;Kekalainen, Eliisa;...
10.1016/j.xcrm.2020.100078
[ 0, 1, 0, 1, 0, 0, 0 ]
[Title]: Systems-Level Immunomonitoring from Acute to Recovery Phase of Severe COVID-19. [Abstract]: Severe disease of SARS-CoV-2 is characterized by vigorous inflammatory responses in the lung, often with a sudden onset after 5-7 days of stable disease. Efforts to modulate this hyperinflammation and the associated acu...
32,617,309
Ann Transl Med
Real-time estimation of the reproduction number of the novel coronavirus disease (COVID-19) in China in 2020 based on incidence data.
Background: Since the first appearance in Wuhan, China in December 2019, the novel coronavirus disease (COVID-19) has posed serious threats to the public health in many Chinese places and overseas. It is essential to quantify the transmissibility on real-time basis for designing public health responses. Methods: We est...
covid-19;modelling;outbreak;reproduction number;serial interval
Journal Article
Wang, Kai;Zhao, Shi;Li, Huling;Song, Yateng;Wang, Lei;Wang, Maggie H;Peng, Zhihang;Li, Hui;He, Daihai
10.21037/atm-20-1944
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: Real-time estimation of the reproduction number of the novel coronavirus disease (COVID-19) in China in 2020 based on incidence data. [Abstract]: Background: Since the first appearance in Wuhan, China in December 2019, the novel coronavirus disease (COVID-19) has posed serious threats to the public health in m...
33,006,256
Adv Biosyst
Home Sample Self-Collection for COVID-19 Patients.
Real-time reverse transcription-polymerase chain reaction (qRT-PCR) using specimens collected from nasopharyngeal and/or oropharyngeal swabs is the standard screening approach for coronavirus disease 2019 (COVID-19). While PCR is rapid and highly accurate, it requires costly laboratory equipment and healthcare professi...
covid-19;sars-cov-2;nasopharyngeal swab;nostril swab;self-collection kits
Journal Article;Research Support, Non-U.S. Gov't;Review
Liao, Wan-Ting;Hsu, Min-Yen;Shen, Ching-Fen;Hung, Kai-Feng;Cheng, Chao-Min
10.1002/adbi.202000150
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Home Sample Self-Collection for COVID-19 Patients. [Abstract]: Real-time reverse transcription-polymerase chain reaction (qRT-PCR) using specimens collected from nasopharyngeal and/or oropharyngeal swabs is the standard screening approach for coronavirus disease 2019 (COVID-19). While PCR is rapid and highly a...
32,674,622
Expert Rev Med Devices
Emerging technologies for diagnostics and drug delivery in the fight against COVID-19 and other pandemics.
INTRODUCTION: A pandemic is the worst-case scenario in the field of infectious diseases. Innovative technologies have the potential to address the challenges associated with the manufacture of personalized drug delivery systems, biosensors, and medical devices during a pandemic. 3D-Printing, microfluidics, and Microele...
3d-printing;covid-19;mems devices;diagnostics;disease monitoring;drug delivery;microfluidics;pandemic;personalized treatment
Journal Article;Review
Lamprou, Dimitrios A
10.1080/17434440.2020.1792287
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Emerging technologies for diagnostics and drug delivery in the fight against COVID-19 and other pandemics. [Abstract]: INTRODUCTION: A pandemic is the worst-case scenario in the field of infectious diseases. Innovative technologies have the potential to address the challenges associated with the manufacture of...
33,053,430
Neurobiol Dis
The SARS-CoV-2 spike protein alters barrier function in 2D static and 3D microfluidic in-vitro models of the human blood-brain barrier.
As researchers across the globe have focused their attention on understanding SARS-CoV-2, the picture that is emerging is that of a virus that has serious effects on the vasculature in multiple organ systems including the cerebral vasculature. Observed effects on the central nervous system include neurological symptoms...
blood-brain barrier;covid-19;cerebral vascular biology;microfluidic chip;neuroinflammation;sars-cov-2;tissue engineering
Journal Article;Research Support, N.I.H., Extramural
Buzhdygan, Tetyana P;DeOre, Brandon J;Baldwin-Leclair, Abigail;Bullock, Trent A;McGary, Hannah M;Khan, Jana A;Razmpour, Roshanak;Hale, Jonathan F;Galie, Peter A;Potula, Raghava;Andrews, Allison M;Ramirez, Servio H
10.1016/j.nbd.2020.105131
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: The SARS-CoV-2 spike protein alters barrier function in 2D static and 3D microfluidic in-vitro models of the human blood-brain barrier. [Abstract]: As researchers across the globe have focused their attention on understanding SARS-CoV-2, the picture that is emerging is that of a virus that has serious effects ...
33,029,269
J Clin Med Res
Could Estrogen Protect Women From COVID-19?
The apparent gender differences in favor of women in the risk of contracting and dying from coronavirus disease 2019 (COVID-19), and the fact that such trends have also been observed in recent epidemics including severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS), have prompted the obv...
covid-19;coronavirus;estrogen;infection;protection
Journal Article;Review
Pirhadi, Roxanna;Sinai Talaulikar, Vikram;Onwude, Joseph;Manyonda, Isaac
10.14740/jocmr4303
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Could Estrogen Protect Women From COVID-19? [Abstract]: The apparent gender differences in favor of women in the risk of contracting and dying from coronavirus disease 2019 (COVID-19), and the fact that such trends have also been observed in recent epidemics including severe acute respiratory syndrome (SARS) a...
32,594,114
Clin Infect Dis
Early Results from SARS-CoV-2 PCR testing of Healthcare Workers at an Academic Medical Center in New York City.
COVID-19 RT-PCR employee-testing was implemented across NYU Langone. Over eight-weeks, 14,764 employees were tested: 33% of symptomatic employees, 8% of asymptomatic employees reporting COVID-19 exposure, 3% of employees returning to work were positive. Positivity rates declined over time possibly reflecting the import...
Journal Article
Nagler, Arielle R;Goldberg, Eric R;Aguero-Rosenfeld, Maria E;Cangiarella, Joan;Kalkut, Gary;Monahan, Carolyn Rooke;Cerfolio, Robert J
10.1093/cid/ciaa867
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: Early Results from SARS-CoV-2 PCR testing of Healthcare Workers at an Academic Medical Center in New York City. [Abstract]: COVID-19 RT-PCR employee-testing was implemented across NYU Langone. Over eight-weeks, 14,764 employees were tested: 33% of symptomatic employees, 8% of asymptomatic employees reporting C...
32,784,770
Int J Mol Sci
Development and Evaluation of Novel and Highly Sensitive Single-Tube Nested Real-Time RT-PCR Assays for SARS-CoV-2 Detection.
Sensitive molecular assays are critical for coronavirus disease 2019 (COVID-19) diagnosis. Here, we designed and evaluated two single-tube nested (STN) real-time RT-PCR assays, targeting SARS-CoV-2 RdRp/Hel and N genes. Both STN assays had a low limit of detection and did not cross react with other human coronaviruses ...
covid-19;rt-pcr;sars-cov-2;evaluation;single-tube nested
Evaluation Study;Journal Article
Yip, Cyril Chik-Yan;Sridhar, Siddharth;Leung, Kit-Hang;Ng, Anthony Chin-Ki;Chan, Kwok-Hung;Chan, Jasper Fuk-Woo;Tsang, Owen Tak-Yin;Hung, Ivan Fan-Ngai;Cheng, Vincent Chi-Chung;Yuen, Kwok-Yung;To, Kelvin Kai-Wang
10.3390/ijms21165674
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Development and Evaluation of Novel and Highly Sensitive Single-Tube Nested Real-Time RT-PCR Assays for SARS-CoV-2 Detection. [Abstract]: Sensitive molecular assays are critical for coronavirus disease 2019 (COVID-19) diagnosis. Here, we designed and evaluated two single-tube nested (STN) real-time RT-PCR assa...
32,542,914
Pediatr Transplant
Varying presentations of COVID-19 in young heart transplant recipients: A case series.
BACKGROUND: Immunosuppression is considered a risk factor for more severe clinical presentation of COVID-19. Limited data regarding clinical outcome exist in adults, whereas very little is known about the spectrum of the disease in pediatric heart transplant recipients. METHODS: We retrospectively reviewed the charts o...
covid-19;heart transplantation;immunosuppression;pediatrics
Case Reports
Lee, Hannah;Mantell, Benjamin S;Richmond, Marc E;Law, Sabrina P;Zuckerman, Warren A;Addonizio, Linda J;Lee, Teresa M;Lytrivi, Irene D
10.1111/petr.13780
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Varying presentations of COVID-19 in young heart transplant recipients: A case series. [Abstract]: BACKGROUND: Immunosuppression is considered a risk factor for more severe clinical presentation of COVID-19. Limited data regarding clinical outcome exist in adults, whereas very little is known about the spectru...
32,612,615
Front Immunol
Immune Response, Inflammation, and the Clinical Spectrum of COVID-19.
The current COVID-19 pandemic began in December 2019 in Wuhan (China) and rapidly extended to become a global sanitary and economic emergency. Its etiological agent is the coronavirus SARS-CoV-2. COVID-19 presents a wide spectrum of clinical manifestations, which ranges from an asymptomatic infection to a severe pneumo...
covid-19;sars-cov-2;t cells;antibodies;cytokines;immune response;inflammation;spectrum
Journal Article;Review
Garcia, Luis F
10.3389/fimmu.2020.01441
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: Immune Response, Inflammation, and the Clinical Spectrum of COVID-19. [Abstract]: The current COVID-19 pandemic began in December 2019 in Wuhan (China) and rapidly extended to become a global sanitary and economic emergency. Its etiological agent is the coronavirus SARS-CoV-2. COVID-19 presents a wide spectrum...
33,020,726
Diabetol Int
Behavioral changes in patients with diabetes during the COVID-19 pandemic.
Aims/Introduction: Amid the coronavirus disease (COVID-19) pandemic, the Japanese government declared a state of emergency and urged people to stay at home to prevent disease transmission. Herein, we investigated this emergency situation's effect on diabetes patients' lifestyle and glycemic control. Materials and metho...
covid-19;diet;physical activity;stay-at-home;teleworking
Journal Article
Kishimoto, Miyako;Ishikawa, Takuya;Odawara, Masato
10.1007/s13340-020-00467-1
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Behavioral changes in patients with diabetes during the COVID-19 pandemic. [Abstract]: Aims/Introduction: Amid the coronavirus disease (COVID-19) pandemic, the Japanese government declared a state of emergency and urged people to stay at home to prevent disease transmission. Herein, we investigated this emerge...
32,767,527
Arthritis Rheumatol
Susceptibility to COVID-19 in Patients Treated With Antimalarials: A Population Based Study in Emilia-Romagna, Northern Italy.
OBJECTIVE: To evaluate the susceptibility to coronavirus disease 2019 (COVID-19) in patients with autoimmune conditions treated with antimalarials in a population-based study. METHODS: All residents treated with chloroquine (CQ)/hydroxychloroquine (HCQ) from July through December 2019 and living in 3 provinces of Regio...
Journal Article
Salvarani, Carlo;Mancuso, Pamela;Gradellini, Federica;Viani, Nilla;Pandolfi, Paolo;Reta, Massimo;Carrozzi, Giuliano;Sandri, Gilda;Bajocchi, Gianluigi;Galli, Elena;Muratore, Francesco;Boiardi, Luigi;Pipitone, Nicolo;Cassone, Giulia;Croci, Stefania;Marata, Anna Maria;Costantini, Massimo;Giorgi Rossi, Paolo
10.1002/art.41475
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Susceptibility to COVID-19 in Patients Treated With Antimalarials: A Population Based Study in Emilia-Romagna, Northern Italy. [Abstract]: OBJECTIVE: To evaluate the susceptibility to coronavirus disease 2019 (COVID-19) in patients with autoimmune conditions treated with antimalarials in a population-based stu...
32,107,119
Transfus Med Rev
Coronavirus Disease 2019: Coronaviruses and Blood Safety.
With the outbreak of unknown pneumonia in Wuhan, China, in December 2019, a new coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), aroused the attention of the entire world. The current outbreak of infections with SARS-CoV-2 is termed Coronavirus Disease 2019 (COVID-19). The World Health Organiz...
2019-ncov;blood safety;covid-19;coronavirus;mers;pathogen inactivation technology;sars;sars-cov-2
Journal Article;Review
Chang, Le;Yan, Ying;Wang, Lunan
10.1016/j.tmrv.2020.02.003
[ 0, 0, 0, 0, 1, 0, 0 ]
[Title]: Coronavirus Disease 2019: Coronaviruses and Blood Safety. [Abstract]: With the outbreak of unknown pneumonia in Wuhan, China, in December 2019, a new coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), aroused the attention of the entire world. The current outbreak of infections with SAR...
32,794,457
J Infect Dev Ctries
Containment of COVID-19: the unprecedented response of Saudi Arabia.
The emergence of a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-COV-2), from Wuhan, China, in December 2019 has challenged many countries. The current pandemic caused by this coronavirus has already negatively affected millions of people and the economies of countries worldwide. However, the...
covid-19;infectious diseases;sars-cov-2;saudi arabia
Journal Article;Review
Obied, Dalia A;Alhamlan, Fatimah S;Al-Qahtani, Ahmed A;Al-Ahdal, Mohammed N
10.3855/jidc.13203
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Containment of COVID-19: the unprecedented response of Saudi Arabia. [Abstract]: The emergence of a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-COV-2), from Wuhan, China, in December 2019 has challenged many countries. The current pandemic caused by this coronavirus has already neg...
32,315,282
Emerg Infect Dis
Estimation of Coronavirus Disease Case-Fatality Risk in Real Time.
We ran a simulation comparing 3 methods to calculate case-fatality risk for coronavirus disease using parameters described in previous studies. Case-fatality risk calculated from these methods all are biased at the early stage of the epidemic. When comparing real-time case-fatality risk, the current trajectory of the e...
2019 novel coronavirus disease;covid-19;sars;sars-cov-2;coronavirus;coronavirus disease;respiratory infections;severe acute respiratory syndrome coronavirus 2;viruses;zoonoses
Journal Article
Ge, Yang;Sun, Shengzhi
10.3201/eid2608.201096
[ 0, 0, 0, 0, 0, 1, 0 ]
[Title]: Estimation of Coronavirus Disease Case-Fatality Risk in Real Time. [Abstract]: We ran a simulation comparing 3 methods to calculate case-fatality risk for coronavirus disease using parameters described in previous studies. Case-fatality risk calculated from these methods all are biased at the early stage of th...
32,756,178
Medicine (Baltimore)
Prognosis of COVID-19 in patients with breast cancer: A protocol for systematic review and meta-analysis.
BACKGROUND: Coronavirus disease 2019 (COVID-19) has become a pandemic in the world and posed a great threat to people's health. Several meta-analyses have indicated that many comorbidities were associated with increased risk of COVID-19 severity or mortality. The original report also showed that the mortality rate of C...
Journal Article
Sheng, Zhijuan;Zhang, Li;Liu, Xinlu;Yuan, Li;Li, Fei;Dai, Dingmei;Wu, Shuilin;Yang, Jingzhi
10.1097/MD.0000000000021487
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Prognosis of COVID-19 in patients with breast cancer: A protocol for systematic review and meta-analysis. [Abstract]: BACKGROUND: Coronavirus disease 2019 (COVID-19) has become a pandemic in the world and posed a great threat to people's health. Several meta-analyses have indicated that many comorbidities were...
32,996,197
Phytother Res
Arenaria kansuensis attenuates pulmonary fibrosis in mice via the activation of Nrf2 pathway and the inhibition of NF-kB/TGF-beta1/Smad2/3 pathway.
Pulmonary fibrosis is a key feature of COVID-19, Chinese herbal medicine Arenaria kansuensis has been used for curing pulmonary disease and antivirus for a long time and it has the potential against COVID-19. In this work, protective effect of A. kansuensis ethanol extract (AE) on pulmonary fibrosis was evaluated throu...
arenaria kansuensis;covid-19;inflammation;oxidative stress;pulmonary fibrosis
Journal Article
Cui, Yulei;Xin, Huawei;Tao, Yanduo;Mei, Lijuan;Wang, Zhen
10.1002/ptr.6857
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Arenaria kansuensis attenuates pulmonary fibrosis in mice via the activation of Nrf2 pathway and the inhibition of NF-kB/TGF-beta1/Smad2/3 pathway. [Abstract]: Pulmonary fibrosis is a key feature of COVID-19, Chinese herbal medicine Arenaria kansuensis has been used for curing pulmonary disease and antivirus f...
32,837,584
Cell Mol Bioeng
Animal Models to Study Emerging Technologies Against SARS-CoV-2.
New technologies are being developed toward the novel coronavirus SARS-CoV-2 to understand its pathogenesis and transmission, to develop therapeutics and vaccines, and to formulate preventive strategies. Animal models are indispensable to understand these processes and develop and test emerging technologies; however, t...
ace2 receptor;covid-19;diagnostics;domestic pets;farm animals;non-human primates;pathogenesis;transgenic models;vaccine studies
Journal Article
Mullick, Jhinuk Basu;Simmons, Chelsey S;Gaire, Janak
10.1007/s12195-020-00638-9
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Animal Models to Study Emerging Technologies Against SARS-CoV-2. [Abstract]: New technologies are being developed toward the novel coronavirus SARS-CoV-2 to understand its pathogenesis and transmission, to develop therapeutics and vaccines, and to formulate preventive strategies. Animal models are indispensabl...
33,050,404
Nutrients
Nutrition Behaviors in Polish Adults before and during COVID-19 Lockdown.
Unexpected isolation, which has not yet been seen on a global scale, has created the conditions for evaluating nutrition in a situation of reduced spatial activity. The study aimed to assess the influence of lockdown on selected eating habits of Polish adults. An anonymous questionnaire was conducted, including questio...
covid-19;eating habits;food consumption;lockdown;social distancing
Journal Article
Blaszczyk-Bebenek, Ewa;Jagielski, Pawel;Boleslawska, Izabela;Jagielska, Anna;Nitsch-Osuch, Aneta;Kawalec, Pawel
10.3390/nu12103084
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Nutrition Behaviors in Polish Adults before and during COVID-19 Lockdown. [Abstract]: Unexpected isolation, which has not yet been seen on a global scale, has created the conditions for evaluating nutrition in a situation of reduced spatial activity. The study aimed to assess the influence of lockdown on selec...
32,873,700
J Clin Pathol
Gene of the month: TMPRSS2 (transmembrane serine protease 2).
Transmembrane serine protease 2 is encoded by the TMPRSS2 gene. The gene is widely conserved and has two isoforms, both being autocatalytically activated from the inactive zymogen form. A fusion gene between the TMPRSS2 gene and ERG (erythroblast-specific-related gene), an oncogenic transcription factor, is the most co...
carcinoma;enzymes;genetics;prostate;virology
Journal Article;Review
Thunders, Michelle;Delahunt, Brett
10.1136/jclinpath-2020-206987
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Gene of the month: TMPRSS2 (transmembrane serine protease 2). [Abstract]: Transmembrane serine protease 2 is encoded by the TMPRSS2 gene. The gene is widely conserved and has two isoforms, both being autocatalytically activated from the inactive zymogen form. A fusion gene between the TMPRSS2 gene and ERG (ery...
32,779,808
Transpl Infect Dis
COVID-19 in solid organ transplant recipients: No difference in survival compared to general population.
Coronavirus disease 2019 (COVID-19) may be associated with worse outcome in solid organ transplant (SOT) recipients. We performed a prospective cohort study of hospitalized patients with confirmed diagnosis of COVID-19, from March 15 to April 30, 2020, at two tertiary hospitals in Emilia-Romagna Region. SOT recipients ...
covid-19;sars-cov-2;solid organ transplantation
Journal Article
Rinaldi, Matteo;Bartoletti, Michele;Bussini, Linda;Pancaldi, Livia;Pascale, Renato;Comai, Giorgia;Morelli, Mariacristina;Ravaioli, Matteo;Cescon, Matteo;Cristini, Francesco;Viale, Pierluigi;Giannella, Maddalena
10.1111/tid.13421
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: COVID-19 in solid organ transplant recipients: No difference in survival compared to general population. [Abstract]: Coronavirus disease 2019 (COVID-19) may be associated with worse outcome in solid organ transplant (SOT) recipients. We performed a prospective cohort study of hospitalized patients with confirm...
32,848,788
Front Pharmacol
DPP-4 Inhibitors in the Prevention/Treatment of Pulmonary Fibrosis, Heart and Kidney Injury Caused by COVID-19-A Therapeutic Approach of Choice in Type 2 Diabetic Patients?
Since the outbreak of SARS-CoV-2 virus more than 12,500,000 cases have been reported worldwide. Patients suffering from diabetes and other comorbidities are particularly susceptible to severe forms of the COVID-19, which might result in chronic complications following recovery. Dipeptidyl peptidase-4 inhibitors exert b...
covid-19;dpp-4 inhibitors;diabetes;fibrosis;multi-organ injury
Journal Article
Smelcerovic, Andrija;Kocic, Gordana;Gajic, Mihajlo;Tomovic, Katarina;Djordjevic, Vukica;Stankovic-Djordjevic, Dobrila;Anderluh, Marko
10.3389/fphar.2020.01185
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: DPP-4 Inhibitors in the Prevention/Treatment of Pulmonary Fibrosis, Heart and Kidney Injury Caused by COVID-19-A Therapeutic Approach of Choice in Type 2 Diabetic Patients? [Abstract]: Since the outbreak of SARS-CoV-2 virus more than 12,500,000 cases have been reported worldwide. Patients suffering from diabet...
33,043,447
Eur J Clin Invest
The De Ritis ratio as prognostic biomarker of in-hospital mortality in COVID-19 patients.
Increased concentrations of serum aspartate transaminase (AST) and alanine transaminase (ALT) are common in COVID-19 patients. However, their capacity to predict mortality, particularly the AST/ALT ratio, commonly referred to as the De Ritis ratio, is unknown. We investigated the association between the De Ritis ratio ...
alt;ast;covid-19;de ritis ratio
Journal Article
Zinellu, Angelo;Arru, Francesco;De Vito, Andrea;Sassu, Alessandro;Valdes, Giovanni;Scano, Valentina;Zinellu, Elisabetta;Perra, Roberto;Madeddu, Giordano;Carru, Ciriaco;Pirina, Pietro;Mangoni, Arduino A;Babudieri, Sergio;Fois, Alessandro G
10.1111/eci.13427
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: The De Ritis ratio as prognostic biomarker of in-hospital mortality in COVID-19 patients. [Abstract]: Increased concentrations of serum aspartate transaminase (AST) and alanine transaminase (ALT) are common in COVID-19 patients. However, their capacity to predict mortality, particularly the AST/ALT ratio, comm...
32,989,148
Proc Natl Acad Sci U S A
Global COVID-19 pandemic demands joint interventions for the suppression of future waves.
Emerging evidence suggests a resurgence of COVID-19 in the coming years. It is thus critical to optimize emergency response planning from a broad, integrated perspective. We developed a mathematical model incorporating climate-driven variation in community transmissions and movement-modulated spatial diffusions of COVI...
climate;disease transmission;hierarchical intervention network;human behavior;international collaboration
Journal Article;Research Support, Non-U.S. Gov't
Li, Ruiyun;Chen, Bin;Zhang, Tao;Ren, Zhehao;Song, Yimeng;Xiao, Yixiong;Hou, Lin;Cai, Jun;Xu, Bo;Li, Miao;Chan, Karen Kie Yan;Tu, Ying;Yang, Mu;Yang, Jing;Liu, Zhaoyang;Shen, Chong;Wang, Che;Xu, Lei;Liu, Qiyong;Bao, Shuming;Zhang, Jianqin;Bi, Yuhai;Bai, Yuqi;Deng, Ke;Zhang, Wusheng;Huang, Wenyu;Whittington, Jason D;Sten...
10.1073/pnas.2012002117
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Global COVID-19 pandemic demands joint interventions for the suppression of future waves. [Abstract]: Emerging evidence suggests a resurgence of COVID-19 in the coming years. It is thus critical to optimize emergency response planning from a broad, integrated perspective. We developed a mathematical model inco...
33,069,265
Am J Trop Med Hyg
The Identification of First COVID-19 Cluster in Indonesia.
We describe the first 11 detected COVID-19 cases in Indonesia, resulting from a local transmission occurring in a club and a restaurant. The virus was detected until an average of 21.3 days (range: 11-25, SD: 4.1) after the onset of illness, and the partial N gene sequences (28,321-28,707 nucleotide position) had 100% ...
Journal Article
Setiawaty, Vivi;Kosasih, Herman;Mardian, Yan;Ajis, Emita;Prasetyowati, Endang Burni;Siswanto;Karyana, Muhammad;Sars-CoV-Reference Laboratory Ministry Of Health Indonesia
10.4269/ajtmh.20-0554
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: The Identification of First COVID-19 Cluster in Indonesia. [Abstract]: We describe the first 11 detected COVID-19 cases in Indonesia, resulting from a local transmission occurring in a club and a restaurant. The virus was detected until an average of 21.3 days (range: 11-25, SD: 4.1) after the onset of illness...
32,841,212
J Clin Invest
Peripheral CD4+ T cell subsets and antibody response in COVID-19 convalescent individuals.
BACKGROUNDMarked progress is achieved in understanding the physiopathology of coronavirus disease 2019 (COVID-19), which caused a global pandemic. However, the CD4+ T cell population critical for antibody response in COVID-19 is poorly understood.METHODSIn this study, we provided a comprehensive analysis of peripheral ...
adaptive immunity;covid-19;immunoglobulins;immunology;t cells
Clinical Trial;Journal Article;Multicenter Study;Research Support, Non-U.S. Gov't
Gong, Fang;Dai, Yaping;Zheng, Ting;Cheng, Liang;Zhao, Dan;Wang, Hao;Liu, Min;Pei, Hao;Jin, Tengchuan;Yu, Di;Zhou, Pengcheng
10.1172/JCI141054
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: Peripheral CD4+ T cell subsets and antibody response in COVID-19 convalescent individuals. [Abstract]: BACKGROUNDMarked progress is achieved in understanding the physiopathology of coronavirus disease 2019 (COVID-19), which caused a global pandemic. However, the CD4+ T cell population critical for antibody res...
32,815,513
Am J Trop Med Hyg
Case Report: COVID-19 Recovery from Triple Infection with Mycobacterium tuberculosis, HIV, and SARS-CoV-2.
COVID-19, designated as SARS-CoV-2, has caused millions of infections worldwide, including in patients with concomitant infections. Here, we report two unusual cases of patients with triple infections of SARS-CoV-2, Mycobacterium tuberculosis, and HIV. Both cases were confirmed through microbiological and immunological...
Case Reports;Journal Article
Rivas, Neyla;Espinoza, Mario;Loban, Alejandra;Luque, Odemaris;Jurado, Julio;Henry-Hurtado, Nicolas;Goodridge, Amador
10.4269/ajtmh.20-0756
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Case Report: COVID-19 Recovery from Triple Infection with Mycobacterium tuberculosis, HIV, and SARS-CoV-2. [Abstract]: COVID-19, designated as SARS-CoV-2, has caused millions of infections worldwide, including in patients with concomitant infections. Here, we report two unusual cases of patients with triple in...
32,656,713
Neurol Sci
Frequency and outcome of olfactory impairment and sinonasal involvement in hospitalized patients with COVID-19.
BACKGROUND: Olfactory dysfunction has shown to accompany COVID-19. There are varying data regarding the exact frequency in the various study population. The outcome of the olfactory impairment is also not clearly defined. OBJECTIVE: To find the frequency of olfactory impairment and its outcome in hospitalized patients ...
olfaction disorders;pandemics;smell;taste
Journal Article
Jalessi, Maryam;Barati, Mitra;Rohani, Mohammad;Amini, Elahe;Ourang, Anis;Azad, Zahra;Hosseinzadeh, Farideh;Cavallieri, Francesco;Ghadirpour, Reza;Valzania, Franco;Iaccarino, Corrado;Ahmadzadeh, Arman;Farhadi, Mohammad
10.1007/s10072-020-04590-4
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Frequency and outcome of olfactory impairment and sinonasal involvement in hospitalized patients with COVID-19. [Abstract]: BACKGROUND: Olfactory dysfunction has shown to accompany COVID-19. There are varying data regarding the exact frequency in the various study population. The outcome of the olfactory impai...
32,654,049
Int J Clin Oncol
Evaluation of COVID 19 infection in 279 cancer patients treated during a 90-day period in 2020 pandemic.
BACKGROUND: The aim of this study was investigation of COVID-19 disease and its outcome in cancer patients who needed treatment, in a 90-day period. METHODS: Cancer patient who required treatment, were evaluated for potential COVID-19 infection in a 90-day period, starting from beginning of this epidemic in Iran, Janua...
covid-19;cancer;hematology tumor;solid tumor;treatment
Journal Article
Aznab, Mozaffar
10.1007/s10147-020-01734-6
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Evaluation of COVID 19 infection in 279 cancer patients treated during a 90-day period in 2020 pandemic. [Abstract]: BACKGROUND: The aim of this study was investigation of COVID-19 disease and its outcome in cancer patients who needed treatment, in a 90-day period. METHODS: Cancer patient who required treatmen...
33,070,480
Isr Med Assoc J
Inhalation Sedation During the COVID-19 Outbreak: An Expert Opinion.
BACKGROUND: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the pathogen that causes coronavirus disease-2019 (COVID-19), is thought to be transmitted via droplets and aerosols, and was detected in saliva of infected individuals. These droplets from the upper airway may infect the inhalation sedation mask...
Journal Article;Review
Yanko, Robert;Klitinich, Valeri;Haviv, Yaron;Gozal, David;Aframian, Doron J;Ratman, Andra
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Inhalation Sedation During the COVID-19 Outbreak: An Expert Opinion. [Abstract]: BACKGROUND: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the pathogen that causes coronavirus disease-2019 (COVID-19), is thought to be transmitted via droplets and aerosols, and was detected in saliva of infected...
32,992,291
Vet Microbiol
Porcine deltacoronavirus nucleocapsid protein species-specifically suppressed IRF7-induced type I interferon production via ubiquitin-proteasomal degradation pathway.
Coronaviruses (CoVs) is showing obvious interspecies transmission, such as the SARS-CoV, MERS-CoV and SARS-CoV-2. Here, the emerging porcine deltacoronavirus (PDCoV) strain, isolated from Shanghai, China, broadly infects porcine, human and chicken cells in vitro. Previously studies by our group and others have confirme...
nucleocapsid;pdcov;porcine irf7;species-specific;ubiquitin-proteasome pathway
Journal Article
Ji, Likai;Wang, Na;Ma, Jingjiao;Cheng, Yuqiang;Wang, Hengan;Sun, Jianhe;Yan, Yaxian
10.1016/j.vetmic.2020.108853
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Porcine deltacoronavirus nucleocapsid protein species-specifically suppressed IRF7-induced type I interferon production via ubiquitin-proteasomal degradation pathway. [Abstract]: Coronaviruses (CoVs) is showing obvious interspecies transmission, such as the SARS-CoV, MERS-CoV and SARS-CoV-2. Here, the emerging...
32,798,227
Urol J
Iranian Urology Association Coronavirus Disease 2019 (COVID-19) Taskforce Pamphlet (IUA-CTP) Recommended Practice based on National Epidemiologic Analysis.
Since the emergence of Covid19 epidemics different guidelines and protocols have been published by Urology associations. Most of these recommendations have focused on the aptitude of any disease or condition for postponement. With the evolution of the outbreak, it is clear that postponement of procedures is not the pol...
Journal Article;Review
Ghahestani, Seyed Mohammad;Bonakdar Hashemi, Milad;Yousefzadeh Kandevani, Naser;Borumandnia, Nasrin;Dadpour, Mehdi;Sharifiaghdas, Farzaneh
10.22037/uj.v16i7.6372
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Iranian Urology Association Coronavirus Disease 2019 (COVID-19) Taskforce Pamphlet (IUA-CTP) Recommended Practice based on National Epidemiologic Analysis. [Abstract]: Since the emergence of Covid19 epidemics different guidelines and protocols have been published by Urology associations. Most of these recommen...
32,365,567
Micromachines (Basel)
Lab-on-a-Chip Technologies for the Single Cell Level: Separation, Analysis, and Diagnostics.
In the last three decades, microfluidics and its applications have been on an exponential rise, including approaches to isolate rare cells and diagnose diseases on the single-cell level. The techniques mentioned herein have already had significant impacts in our lives, from in-the-field diagnosis of disease and parasit...
biomedical engineering;cancer;diagnostics;infectious diseases;microfluidics;parasites;point-of-care;single cell level
Journal Article;Review
Hochstetter, Axel
10.3390/mi11050468
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Lab-on-a-Chip Technologies for the Single Cell Level: Separation, Analysis, and Diagnostics. [Abstract]: In the last three decades, microfluidics and its applications have been on an exponential rise, including approaches to isolate rare cells and diagnose diseases on the single-cell level. The techniques ment...
32,419,400
J Korean Med Sci
Social Distancing against COVID-19: Implication for the Control of Influenza.
Social distancing has been adopted as one of basic protective measures against coronavirus disease 2019 (COVID-19). During 2019-2020 season, influenza epidemic period was exceptionally short and epidemic peak was low in comparison with previous seasons in Korea. Influenza epidemic pattern was bimodal in 2016-2017 and 2...
coronavirus disease 2019;influenza;social distancing
Journal Article
Noh, Ji Yun;Seong, Hye;Yoon, Jin Gu;Song, Joon Young;Cheong, Hee Jin;Kim, Woo Joo
10.3346/jkms.2020.35.e182
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Social Distancing against COVID-19: Implication for the Control of Influenza. [Abstract]: Social distancing has been adopted as one of basic protective measures against coronavirus disease 2019 (COVID-19). During 2019-2020 season, influenza epidemic period was exceptionally short and epidemic peak was low in c...
32,428,957
Dtsch Med Wochenschr
[Coronavirus (SARS-CoV-2) - Outbreak in North Rhine-Westphalia (District of Heinsberg) - First diagnosis of a COVID-19 manifestation in a couple].
HISTORY AND CLINICAL FINDINGS: Up to February 24(th) 2020 occasionally occuring SARS-CoV-2 infections in Germany without severe course. Emergency presentation of a couple in the emergency room. For seven days now, the man has fever, dry cough und physical weakness and the wife has similar symptoms of a milder form. The...
Case Reports;Journal Article
Laufs, Jendrik;Elsbernd, Harry;Holzl, Friedrich;Winter, Klaus-Dieter
10.1055/a-1163-1335
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: [Coronavirus (SARS-CoV-2) - Outbreak in North Rhine-Westphalia (District of Heinsberg) - First diagnosis of a COVID-19 manifestation in a couple]. [Abstract]: HISTORY AND CLINICAL FINDINGS: Up to February 24(th) 2020 occasionally occuring SARS-CoV-2 infections in Germany without severe course. Emergency presen...
32,491,112
Rev Saude Publica
Does Vitamin D play a role in the management of Covid-19 in Brazil?
The study discusses the possible role of adequate vitamin D status in plasma or serum for preventing acute respiratory infections during the Covid-19 pandemic. Our arguments respond to an article, published in Italy, that describes the high prevalence of hypovitaminosis D in older Italian women and raises the possible ...
Journal Article
Ribeiro, Helena;Santana, Keila Valente de Souza de;Oliver, Sofia Lizarralde;Rondo, Patricia Helen de Carvalho;Mendes, Marcela Moraes;Charlton, Karen;Lanham-New, Susan
10.11606/s1518-8787.2020054002545
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Does Vitamin D play a role in the management of Covid-19 in Brazil? [Abstract]: The study discusses the possible role of adequate vitamin D status in plasma or serum for preventing acute respiratory infections during the Covid-19 pandemic. Our arguments respond to an article, published in Italy, that describes...
32,894,564
Eur Rev Med Pharmacol Sci
The effects of COVID-19 pandemic on elective post-bariatric surgery waiting list: a single Plastic Surgery Center investigation.
OBJECTIVE: After massive weight loss, patients that meet specific criteria can be inserted in an ad-hoc post-bariatric surgery list in order to be subjected to body contouring procedures. During COVID-19 pandemic, the Italian National Health System has been overwhelmed by the continue load of life-threatening patients ...
Journal Article
Marruzzo, G;Redi, U;Patane, L;Cavalieri, E;Frattaroli, J M;D'Ermo, G;Lo Torto, F;Carella, S;Grippaudo, F R;Ribuffo, D
10.26355/eurrev_202008_22656
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The effects of COVID-19 pandemic on elective post-bariatric surgery waiting list: a single Plastic Surgery Center investigation. [Abstract]: OBJECTIVE: After massive weight loss, patients that meet specific criteria can be inserted in an ad-hoc post-bariatric surgery list in order to be subjected to body conto...
32,634,024
Ann Intern Med
How to Quantify and Interpret Treatment Effects in Comparative Clinical Studies of COVID-19.
Clinical trials of treatments for coronavirus disease 2019 (COVID-19) draw intense public attention. More than ever, valid, transparent, and intuitive summaries of the treatment effects, including efficacy and harm, are needed. In recently published and ongoing randomized comparative trials evaluating treatments for CO...
Journal Article;Review
McCaw, Zachary R;Tian, Lu;Vassy, Jason L;Ritchie, Christine Seel;Lee, Chien-Chang;Kim, Dae Hyun;Wei, Lee-Jen
10.7326/M20-4044
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: How to Quantify and Interpret Treatment Effects in Comparative Clinical Studies of COVID-19. [Abstract]: Clinical trials of treatments for coronavirus disease 2019 (COVID-19) draw intense public attention. More than ever, valid, transparent, and intuitive summaries of the treatment effects, including efficacy ...
32,997,807
CA Cancer J Clin
Planning for post-pandemic cancer care delivery: Recovery or opportunity for redesign?
The delivery of cancer care has never changed as rapidly and dramatically as we have seen with the coronavirus disease 2019 (COVID-19) pandemic. During the early phase of the pandemic, recommendations for the management of oncology patients issued by various professional societies and government agencies did not recogn...
cancer care delivery;coronavirus disease 2019 (covid-19);health care delivery;pandemics
Journal Article
Cinar, Pelin;Bold, Richard;Bosslet, Bryn A;Bota, Daniela A;Burgess, Debra;Chew, Helen K;Cohen, Joshua G;Elquza, Emad;Gold, Kathryn A;Kamiya, Emi;Karlan, Beth Y;McKay, Rana R;Patel, Sandip P;Ternavan, Kimberly;Welborn, Jeanna;Yamamoto, Maki;Rugo, Hope S
10.3322/caac.21644
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Planning for post-pandemic cancer care delivery: Recovery or opportunity for redesign? [Abstract]: The delivery of cancer care has never changed as rapidly and dramatically as we have seen with the coronavirus disease 2019 (COVID-19) pandemic. During the early phase of the pandemic, recommendations for the man...
32,970,772
PLoS One
Lipoprotein concentrations over time in the intensive care unit COVID-19 patients: Results from the ApoCOVID study.
INTRODUCTION: Severe acute respiratory syndrome coronavirus2 has caused a global pandemic of coronavirus disease 2019 (COVID-19). High-density lipoproteins (HDLs), particles chiefly known for their reverse cholesterol transport function, also display pleiotropic properties, including anti-inflammatory or antioxidant fu...
Journal Article
Tanaka, Sebastien;De Tymowski, Christian;Assadi, Maksud;Zappella, Nathalie;Jean-Baptiste, Sylvain;Robert, Tiphaine;Peoc'h, Katell;Lortat-Jacob, Brice;Fontaine, Lauriane;Bouzid, Donia;Tran-Dinh, Alexy;Tashk, Parvine;Meilhac, Olivier;Montravers, Philippe
10.1371/journal.pone.0239573
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Lipoprotein concentrations over time in the intensive care unit COVID-19 patients: Results from the ApoCOVID study. [Abstract]: INTRODUCTION: Severe acute respiratory syndrome coronavirus2 has caused a global pandemic of coronavirus disease 2019 (COVID-19). High-density lipoproteins (HDLs), particles chiefly k...
33,078,124
Indian J Otolaryngol Head Neck Surg
Testing Olfactory and Gustatory Dysfunctions among Quarantine COVID-19 Suspects.
The World Health Organization (WHO) has cautioned on specific respiratory symptoms for suspecting an individual of Corona Virus Disease 2019 (COVID-19). Meanwhile, many suspects are reporting dysfunctions of smell and taste. This study aimed to investigate the percentage of positive COVID-19 who had associated loss of ...
ageusia;anosmia;covid-19;olfactory;sars-cov-2
Journal Article
Bidkar, Vijay;Mishra, Meena;Selvaraj, Kalaiselvi;Joshi, Prashant;H, Shrikrishna B;Dabhekar, Sandeep;Prathipati, Kiran Kumar;Rathod, Bharat Singh;Shendre, Pooja;Gondode, Prakash
10.1007/s12070-020-02210-3
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Testing Olfactory and Gustatory Dysfunctions among Quarantine COVID-19 Suspects. [Abstract]: The World Health Organization (WHO) has cautioned on specific respiratory symptoms for suspecting an individual of Corona Virus Disease 2019 (COVID-19). Meanwhile, many suspects are reporting dysfunctions of smell and ...
32,838,307
Lancet Rheumatol
COVID-19 in patients with rheumatic diseases in northern Italy: a single-centre observational and case-control study.
Background: The highest number of COVID-19 cases in Italy have been reported in Lombardy, a region in northern Italy. We aimed to analyse the course of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in patients with rheumatic and musculoskeletal diseases living in a district of Lombardy with a h...
Journal Article
Fredi, Micaela;Cavazzana, Ilaria;Moschetti, Liala;Andreoli, Laura;Franceschini, Franco
10.1016/S2665-9913(20)30169-7
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: COVID-19 in patients with rheumatic diseases in northern Italy: a single-centre observational and case-control study. [Abstract]: Background: The highest number of COVID-19 cases in Italy have been reported in Lombardy, a region in northern Italy. We aimed to analyse the course of severe acute respiratory synd...
32,861,276
Lancet Respir Med
Pathophysiology of COVID-19-associated acute respiratory distress syndrome: a multicentre prospective observational study.
BACKGROUND: Patients with COVID-19 can develop acute respiratory distress syndrome (ARDS), which is associated with high mortality. The aim of this study was to examine the functional and morphological features of COVID-19-associated ARDS and to compare these with the characteristics of ARDS unrelated to COVID-19. METH...
Comparative Study;Journal Article;Multicenter Study;Observational Study
Grasselli, Giacomo;Tonetti, Tommaso;Protti, Alessandro;Langer, Thomas;Girardis, Massimo;Bellani, Giacomo;Laffey, John;Carrafiello, Gianpaolo;Carsana, Luca;Rizzuto, Chiara;Zanella, Alberto;Scaravilli, Vittorio;Pizzilli, Giacinto;Grieco, Domenico Luca;Di Meglio, Letizia;de Pascale, Gennaro;Lanza, Ezio;Monteduro, Francesc...
10.1016/S2213-2600(20)30370-2
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Pathophysiology of COVID-19-associated acute respiratory distress syndrome: a multicentre prospective observational study. [Abstract]: BACKGROUND: Patients with COVID-19 can develop acute respiratory distress syndrome (ARDS), which is associated with high mortality. The aim of this study was to examine the fun...
32,933,788
Br J Oral Maxillofac Surg
You Have Control: aviation communication application for safety-critical times in surgery.
High-risk organisations (HRO), including aviation, undergo formal communication training, with emphasis on safety-critical moments. Such training is not widespread or mandatory in healthcare, and while there are many differences both share the 'human element' with circumstances leading to an increased risk of harm. A t...
covid-19;aviation;human factors;never event;patient safety;surgery
Journal Article;Review
Hardie, J A;Oeppen, R S;Shaw, G;Holden, C;Tayler, N;Brennan, P A
10.1016/j.bjoms.2020.08.104
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: You Have Control: aviation communication application for safety-critical times in surgery. [Abstract]: High-risk organisations (HRO), including aviation, undergo formal communication training, with emphasis on safety-critical moments. Such training is not widespread or mandatory in healthcare, and while there ...
32,697,970
Cell
Making Sense of Mutation: What D614G Means for the COVID-19 Pandemic Remains Unclear.
In this issue of Cell, Korber et al. found that a SARS-CoV-2 variant in the spike protein D614G rapidly became dominant around the world. Although clinical and in vitro data suggest that D614G changes the virus phenotype, the impact of the mutation on transmission, disease, and vaccine and therapeutic development are l...
Journal Article;Comment
Grubaugh, Nathan D;Hanage, William P;Rasmussen, Angela L
10.1016/j.cell.2020.06.040
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Making Sense of Mutation: What D614G Means for the COVID-19 Pandemic Remains Unclear. [Abstract]: In this issue of Cell, Korber et al. found that a SARS-CoV-2 variant in the spike protein D614G rapidly became dominant around the world. Although clinical and in vitro data suggest that D614G changes the virus ph...
32,485,197
J Hosp Infect
A novel cohorting and isolation strategy for suspected COVID-19 cases during a pandemic.
BACKGROUND: The COVID-19 pandemic presents a significant infection prevention and control challenge. The admission of large numbers of patients with suspected COVID-19 disease risks overwhelming the capacity to protect other patients from exposure. The delay between clinical suspicion and confirmatory testing adds to t...
covid-19;cohorting;infection prevention and control;pandemic;risk stratification;triage
Journal Article
Patterson, B;Marks, M;Martinez-Garcia, G;Bidwell, G;Luintel, A;Ludwig, D;Parks, T;Gothard, P;Thomas, R;Logan, S;Shaw, K;Stone, N;Brown, M
10.1016/j.jhin.2020.05.035
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: A novel cohorting and isolation strategy for suspected COVID-19 cases during a pandemic. [Abstract]: BACKGROUND: The COVID-19 pandemic presents a significant infection prevention and control challenge. The admission of large numbers of patients with suspected COVID-19 disease risks overwhelming the capacity to...
32,765,941
Aging Dis
Bioactive Lipids as Mediators of the Beneficial Action(s) of Mesenchymal Stem Cells in COVID-19.
It is proposed that the beneficial action of mesenchymal stem cells (MSCs) in COVID-19 and other inflammatory diseases could be attributed to their ability to secrete bioactive lipids (BALs) such as prostaglandin E2 (PGE2) and lipoxin A4 (LXA4) and other similar BALs. This implies that MSCs that have limited or low cap...
covid-19;bioactive lipids;cytokines;immune check point inhibitory therapy;inflammation;mesenchymal stem cells
Journal Article
Das, Undurti N
10.14336/AD.2020.0521
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Bioactive Lipids as Mediators of the Beneficial Action(s) of Mesenchymal Stem Cells in COVID-19. [Abstract]: It is proposed that the beneficial action of mesenchymal stem cells (MSCs) in COVID-19 and other inflammatory diseases could be attributed to their ability to secrete bioactive lipids (BALs) such as pro...
32,655,740
J Clin Med Res
Use of Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios in COVID-19.
Background: As the pandemic of coronavirus disease 2019 (COVID-19) continues, prognostic markers are now being identified. The neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are easily accessible values that have been known to correlate with inflammation and prognosis in several conditions....
covid-19;nlr;plr;prognostic markers
Journal Article
Chan, Abigail Sy;Rout, Amit
10.14740/jocmr4240
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Use of Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios in COVID-19. [Abstract]: Background: As the pandemic of coronavirus disease 2019 (COVID-19) continues, prognostic markers are now being identified. The neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are easily access...
32,429,722
J Matern Fetal Neonatal Med
Antenatal corticosteroids for pregnant women with COVID-19 infection and preterm prelabor rupture of membranes: a decision analysis.
Background: While antenatal corticosteroids are routinely used to decrease adverse neonatal outcomes following preterm delivery, corticosteroids are also associated with worse outcomes in patients with viral respiratory infections. Currently in the setting of the COVID-19 pandemic, it is unclear whether antenatal corti...
antenatal corticosteroids;covid-19;decision analysis;preterm delivery;rupture of membranes
Journal Article
Zhou, Clarice G;Packer, Claire H;Hersh, Alyssa R;Caughey, Aaron B
10.1080/14767058.2020.1763951
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Antenatal corticosteroids for pregnant women with COVID-19 infection and preterm prelabor rupture of membranes: a decision analysis. [Abstract]: Background: While antenatal corticosteroids are routinely used to decrease adverse neonatal outcomes following preterm delivery, corticosteroids are also associated w...
32,472,676
Clin Infect Dis
Predictors for Severe COVID-19 Infection.
BACKGROUND: COVID-19 is a pandemic disease caused by a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Predictors for severe COVID-19 infection have not been well defined. Determination of risk factors for severe infection would enable identifying patients who may benefit from aggressiv...
predictors;risk factors;severe covid-19
Journal Article;Observational Study
Bhargava, Ashish;Fukushima, Elisa Akagi;Levine, Miriam;Zhao, Wei;Tanveer, Farah;Szpunar, Susanna M;Saravolatz, Louis
10.1093/cid/ciaa674
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Predictors for Severe COVID-19 Infection. [Abstract]: BACKGROUND: COVID-19 is a pandemic disease caused by a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Predictors for severe COVID-19 infection have not been well defined. Determination of risk factors for severe infection w...
32,904,956
J Vasc Surg Cases Innov Tech
Endovascular aortic repair in an asymptomatic COVID-19-positive patient with a symptomatic inflammatory abdominal aortic aneurysm.
In this report, we present the case of a COVID-19-positive patient whose symptomatic inflammatory abdominal aortic aneurysm was successfully treated with endovascular aortic repair at our institution. We discuss the reasoning behind the type of therapy used and the various lessons learned. Based on our experience with ...
aaa;covid-19;evar;endovascular;symptomatic
Case Reports
Yammine, Halim;Ballast, Jocelyn K;Poulsen, Neil;Arko, Frank R 3rd
10.1016/j.jvscit.2020.08.016
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Endovascular aortic repair in an asymptomatic COVID-19-positive patient with a symptomatic inflammatory abdominal aortic aneurysm. [Abstract]: In this report, we present the case of a COVID-19-positive patient whose symptomatic inflammatory abdominal aortic aneurysm was successfully treated with endovascular a...
32,318,330
Leuk Res Rep
Rewriting the rules for care of MDS and AML patients in the time of COVID-19.
The care of patients with myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) has been radically altered by COVID-19, especially in New York City, the epicenter of the pandemic. Here we summarize how telemedicine, virtual visits, delayed transfusions, and chemotherapy, preferably selecting self-administere...
acute myeloid leukemia;covid-19;myelodysplatic syndromes;stem cell transplantation;telemedicine
Journal Article
Raza, Azra;Assal, Amer;Ali, Abdullah M;Jurcic, Joseph G
10.1016/j.lrr.2020.100201
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Rewriting the rules for care of MDS and AML patients in the time of COVID-19. [Abstract]: The care of patients with myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) has been radically altered by COVID-19, especially in New York City, the epicenter of the pandemic. Here we summarize how telemedi...
32,858,551
J Chin Med Assoc
Using lung ultrasound changes to evaluate the response of recruitment maneuver in a patient recovering from coronavirus disease 2019 with acute respiratory distress syndrome.
Lung ultrasound (LUS) is widely used in intensive care units because it provides timely information noninvasively. The use of LUS is recommended to minimize transfers in critically ill patients with coronavirus disease 2019 (COVID-19) during the pandemic. The clinical efficacies of bedside chest X-ray (CXR) and LUS hav...
Case Reports;Journal Article
Hsiao, Yi-Han;Lin, Yi-Tsung;Liao, Hsien-Tzung;Yang, Kuang-Yao;Chen, Yuh-Min
10.1097/JCMA.0000000000000418
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Using lung ultrasound changes to evaluate the response of recruitment maneuver in a patient recovering from coronavirus disease 2019 with acute respiratory distress syndrome. [Abstract]: Lung ultrasound (LUS) is widely used in intensive care units because it provides timely information noninvasively. The use o...
33,072,781
Front Med (Lausanne)
The Pipeline of Therapeutics Testing During the Emergency Phase of the COVID-19 Outbreak.
The coronavirus disease 19 (COVID-19) pandemic poses a serious threat to the sustainability of healthcare systems and is currently having a significant effect on living conditions worldwide. No therapeutic agent has yet proven to be effective for the treatment of COVID-19. The management of this disease currently relie...
covid-19;sars-cov-2;antivirals;clinical trials;drug development;immunomodulators;research protocols
Systematic Review
Canevelli, Marco;Remoli, Giulia;Trentin, Federica;Riccardi, Gabriele;Tariciotti, Leonardo;Risoleo, Giovanni;Ancidoni, Antonio;Bruno, Giuseppe;Cesari, Matteo;Vanacore, Nicola;Raparelli, Valeria
10.3389/fmed.2020.552991
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: The Pipeline of Therapeutics Testing During the Emergency Phase of the COVID-19 Outbreak. [Abstract]: The coronavirus disease 19 (COVID-19) pandemic poses a serious threat to the sustainability of healthcare systems and is currently having a significant effect on living conditions worldwide. No therapeutic age...
32,980,319
J Pediatr (Rio J)
Extrapulmonary manifestations of COVID-19 in children: a comprehensive review and pathophysiological considerations.
OBJECTIVE: The aim of this review was to summarize the most common extrapulmonary manifestations in pediatric patients with COVID-19, as well as to discuss clinical, epidemiological, and pathophysiological aspects of these clinical presentations in children. SOURCE OF DATA: An extensive search of literature was perform...
covid-19;extrapulmonary;kawasaki like-disease;multisystemic inflammation;pediatric;sars-cov-2
Journal Article;Research Support, Non-U.S. Gov't;Review
Pousa, Pedro A;Mendonca, Tamires S C;Oliveira, Eduardo A;Simoes-E-Silva, Ana Cristina
10.1016/j.jped.2020.08.007
[ 0, 1, 0, 1, 0, 0, 0 ]
[Title]: Extrapulmonary manifestations of COVID-19 in children: a comprehensive review and pathophysiological considerations. [Abstract]: OBJECTIVE: The aim of this review was to summarize the most common extrapulmonary manifestations in pediatric patients with COVID-19, as well as to discuss clinical, epidemiological,...
32,579,293
Pediatr Pulmonol
Clinical characteristics of acute respiratory syndrome with SARS-CoV-2 infection in children in South China.
BACKGROUND: A retrospective study was conducted to summarize the clinical information of childhood infections during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic. METHODS: Children with SARS-CoV-2 infection in 11 hospitals from three provinces of South China were included in the study. Clin...
2019-ncov;covid-19;sars-cov-2;children
Journal Article;Multicenter Study;Research Support, Non-U.S. Gov't
Zheng, Guilang;Wang, Bangqin;Zhang, Hua;Xie, Chuxing;Zhang, Yuehua;Wen, Zhihong;Guo, Qingyun;Zhu, Hong;Ye, Guojing;Liang, Jiayi;Meng, Qiong;Xie, Jingquan;Jiang, Suhua;Liu, Guojun;Gao, Wenjun;Wang, Yanhao;Guo, Yuxiong
10.1002/ppul.24921
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical characteristics of acute respiratory syndrome with SARS-CoV-2 infection in children in South China. [Abstract]: BACKGROUND: A retrospective study was conducted to summarize the clinical information of childhood infections during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic...
32,751,609
Microorganisms
Forecasting the Spreading of COVID-19 across Nine Countries from Europe, Asia, and the American Continents Using the ARIMA Models.
Since mid-November 2019, when the first SARS-CoV-2-infected patient was officially reported, the new coronavirus has affected over 10 million people from which half a million died during this short period. There is an urgent need to monitor, predict, and restrict COVID-19 in a more efficient manner. This is why Auto-Re...
asia;covid-19;europe;sars-cov-2;epidemiological;incidence;prevalence;the american continents
Journal Article
Ilie, Ovidiu-Dumitru;Cojocariu, Roxana-Oana;Ciobica, Alin;Timofte, Sergiu-Ioan;Mavroudis, Ioannis;Doroftei, Bogdan
10.3390/microorganisms8081158
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: Forecasting the Spreading of COVID-19 across Nine Countries from Europe, Asia, and the American Continents Using the ARIMA Models. [Abstract]: Since mid-November 2019, when the first SARS-CoV-2-infected patient was officially reported, the new coronavirus has affected over 10 million people from which half a m...
32,784,601
Nutrients
Early Nutritional Interventions with Zinc, Selenium and Vitamin D for Raising Anti-Viral Resistance Against Progressive COVID-19.
OBJECTIVES: The novel coronavirus infection (COVID-19) conveys a serious threat globally to health and economy because of a lack of vaccines and specific treatments. A common factor for conditions that predispose for serious progress is a low-grade inflammation, e.g., as seen in metabolic syndrome, diabetes, and heart ...
covid-19;coenzyme q10;corona virus;micronutrients;nutritional;selenium;therapy;vitamin a;vitamin d;zinc
Journal Article;Review
Alexander, Jan;Tinkov, Alexey;Strand, Tor A;Alehagen, Urban;Skalny, Anatoly;Aaseth, Jan
10.3390/nu12082358
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Early Nutritional Interventions with Zinc, Selenium and Vitamin D for Raising Anti-Viral Resistance Against Progressive COVID-19. [Abstract]: OBJECTIVES: The novel coronavirus infection (COVID-19) conveys a serious threat globally to health and economy because of a lack of vaccines and specific treatments. A c...
32,269,086
Eur Respir J
Clinical characteristics and outcomes of hospitalised patients with COVID-19 treated in Hubei (epicentre) and outside Hubei (non-epicentre): a nationwide analysis of China.
BACKGROUND: During the outbreak of coronavirus disease 2019 (COVID-19), consistent and considerable differences in disease severity and mortality rate of patients treated in Hubei province compared to those in other parts of China have been observed. We sought to compare the clinical characteristics and outcomes of pat...
Journal Article;Research Support, Non-U.S. Gov't
Liang, Wen-Hua;Guan, Wei-Jie;Li, Cai-Chen;Li, Yi-Min;Liang, Heng-Rui;Zhao, Yi;Liu, Xiao-Qing;Sang, Ling;Chen, Ru-Chong;Tang, Chun-Li;Wang, Tao;Wang, Wei;He, Qi-Hua;Chen, Zi-Sheng;Wong, Sook-San;Zanin, Mark;Liu, Jun;Xu, Xin;Huang, Jun;Li, Jian-Fu;Ou, Li-Min;Cheng, Bo;Xiong, Shan;Xie, Zhan-Hong;Ni, Zheng-Yi;Hu, Yu;Liu, L...
10.1183/13993003.00562-2020
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical characteristics and outcomes of hospitalised patients with COVID-19 treated in Hubei (epicentre) and outside Hubei (non-epicentre): a nationwide analysis of China. [Abstract]: BACKGROUND: During the outbreak of coronavirus disease 2019 (COVID-19), consistent and considerable differences in disease sev...
32,793,517
Front Cell Infect Microbiol
Association Between ABO Blood Group System and COVID-19 Susceptibility in Wuhan.
Background: The ABO blood group system has been associated with multiple infectious diseases, including hepatitis B, dengue haemorrhagic fever and so on. Coronavirus disease 2019 (COVID-19) is a new respiratory infectious disease and the relationship between COVID-19 and ABO blood group system needs to be explored urge...
abo blood group system;covid-19;association analysis;female;lymphocyte count
Journal Article;Research Support, Non-U.S. Gov't
Fan, Qian;Zhang, Wei;Li, Bo;Li, De-Jia;Zhang, Jian;Zhao, Fang
10.3389/fcimb.2020.00404
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Association Between ABO Blood Group System and COVID-19 Susceptibility in Wuhan. [Abstract]: Background: The ABO blood group system has been associated with multiple infectious diseases, including hepatitis B, dengue haemorrhagic fever and so on. Coronavirus disease 2019 (COVID-19) is a new respiratory infecti...
33,075,259
Ann Intern Med
In adults exposed to COVID-19, hydroxychloroquine did not reduce confirmed or probable COVID-19; trial stopped for futility.
SOURCE CITATION: Boulware DR, Pullen MF, Bangdiwala AS, et al. A randomized trial of hydroxychloroquine as postexposure prophylaxis for COVID-19. N Engl J Med. 2020;383:517-25. 32492293.
Journal Article;Comment
Singh, Ameeta;Sonpar, Ashlesha
10.7326/ACPJ202010200-041
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: In adults exposed to COVID-19, hydroxychloroquine did not reduce confirmed or probable COVID-19; trial stopped for futility. [Abstract]: SOURCE CITATION: Boulware DR, Pullen MF, Bangdiwala AS, et al. A randomized trial of hydroxychloroquine as postexposure prophylaxis for COVID-19. N Engl J Med. 2020;383:517-2...
32,558,175
Influenza Other Respir Viruses
Pre-symptomatic transmission of novel coronavirus in community settings.
We used contact tracing to document how COVID-19 was transmitted across 5 generations involving 10 cases, starting with an individual who became ill on January 27. We calculated the incubation period of the cases as the interval between infection and development of symptoms. The median incubation period was 6.0 days (i...
covid-19;china;comorbidity;contact tracing
Journal Article;Research Support, Non-U.S. Gov't
Kong, Dechuan;Zheng, Yang;Wu, Huanyu;Pan, Hao;Wagner, Abram L;Zheng, Yaxu;Gong, Xiaohuan;Zhu, Yiyi;Jin, Bihong;Xiao, Wenjia;Mao, Shenghua;Lin, Sheng;Han, Ruobing;Yu, Xiao;Cui, Peng;Jiang, Chenyan;Fang, Qiwen;Lu, Yihan;Fu, Chen
10.1111/irv.12773
[ 0, 0, 0, 0, 1, 0, 0 ]
[Title]: Pre-symptomatic transmission of novel coronavirus in community settings. [Abstract]: We used contact tracing to document how COVID-19 was transmitted across 5 generations involving 10 cases, starting with an individual who became ill on January 27. We calculated the incubation period of the cases as the interv...
32,433,742
J Infect Dis
Extended ORF8 Gene Region Is Valuable in the Epidemiological Investigation of Severe Acute Respiratory Syndrome-Similar Coronavirus.
Severe acute respiratory syndrome coronavirus (SARS-CoV) was discovered as a novel pathogen in the 2002-2003 SARS epidemic. The emergence and disappearance of this pathogen have brought questions regarding its source and evolution. Within the genome sequences of 281 SARS-CoVs, severe acute respiratory syndrome coronavi...
orf8 gene;sars-cov;sars-cov-2;genotyping method
Journal Article;Research Support, Non-U.S. Gov't
Chen, Shuaiyin;Zheng, Xin;Zhu, Jingyuan;Ding, Ronghua;Jin, Yuefei;Zhang, Weiguo;Yang, HaiYan;Zheng, Yingjuan;Li, Xin;Duan, Guangcai
10.1093/infdis/jiaa278
[ 0, 0, 0, 1, 1, 0, 0 ]
[Title]: Extended ORF8 Gene Region Is Valuable in the Epidemiological Investigation of Severe Acute Respiratory Syndrome-Similar Coronavirus. [Abstract]: Severe acute respiratory syndrome coronavirus (SARS-CoV) was discovered as a novel pathogen in the 2002-2003 SARS epidemic. The emergence and disappearance of this pa...
32,822,220
Clin Appl Thromb Hemost
Drive-Through Model for Anticoagulation Clinics During the COVID-19 Pandemic.
The coronavirus disease of 2019 (COVID-19) has posed a major challenge for providers and patients. A large number of patients with atrial fibrillation, venous thromboembolism, or valvular heart disease are chronically anticoagulated with vitamin K antagonists and rely on frequent follow ups at anticoagulation clinics f...
covid-19;anticoagulation;drive-through clinic
Journal Article
Rezaei Bookani, Kaveh;Minga, Iva;Chander, Manisha;Hankewych, Ksenia;Plassmeier, Matthew;Tafur, Alfonso
10.1177/1076029620947476
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Drive-Through Model for Anticoagulation Clinics During the COVID-19 Pandemic. [Abstract]: The coronavirus disease of 2019 (COVID-19) has posed a major challenge for providers and patients. A large number of patients with atrial fibrillation, venous thromboembolism, or valvular heart disease are chronically ant...
32,834,301
Habitat Int
COVID-19 and urban vulnerability in India.
The global pandemic has an inherently urban character. The UN-Habitat's publication of a Response Plan for mollification of the SARS-CoV-2 based externalities in the cities of the world testifies to that. This article takes the UN-Habitat report as the premise to carry out an empirical investigation in the four major m...
covid-19;covid vulnerability index;lockdown;metro cities;social distancing;un-habitat
Journal Article
Mishra, Swasti Vardhan;Gayen, Amiya;Haque, Sk Mafizul
10.1016/j.habitatint.2020.102230
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 and urban vulnerability in India. [Abstract]: The global pandemic has an inherently urban character. The UN-Habitat's publication of a Response Plan for mollification of the SARS-CoV-2 based externalities in the cities of the world testifies to that. This article takes the UN-Habitat report as the pre...
32,157,264
Recenti Prog Med
[Treatment of early relapsed plasma cells leukemia after unrelated bone marrow transplant with KRD (carfilzomib, lenalidomide and dexamethasone): a case report.]
INTRODUCTION: Plasma cell leukemia (PCL) is a rare but most aggressive form of monoclonal gammopathies, characterized by the presence of clonal cells in peripheral blood and a poor prognosis. There are two forms of PCL: primary, which arise de novo, and secondary which is a leukemic transformation in patients with prev...
Case Reports;Journal Article
Palazzo, Giulia
10.1701/3315.32858
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: [Treatment of early relapsed plasma cells leukemia after unrelated bone marrow transplant with KRD (carfilzomib, lenalidomide and dexamethasone): a case report.] [Abstract]: INTRODUCTION: Plasma cell leukemia (PCL) is a rare but most aggressive form of monoclonal gammopathies, characterized by the presence of ...
32,542,672
Br J Haematol
Rapid screening of COVID-19 patients using white blood cell scattergrams, a study on 381 patients.
Complementary tools are warranted to increase the sensitivity of the initial testing for COVID-19. We identified a specific 'sandglass' aspect on the white blood cell scattergram of COVID-19 patients reflecting the presence of circulating plasmacytoid lymphocytes. Patients were dichotomized as COVID-19-positive or -neg...
covid-19;sars-cov-2;coronavirus;plasmacytoid lymphocytes;white blood cells scattergram
Journal Article
Osman, Jennifer;Lambert, Jerome;Temple, Marie;Devaux, Floriane;Favre, Remy;Flaujac, Claire;Bridoux, Delphine;Marque-Juillet, Stephanie;Bruneel, Fabrice;Mignon, Francois;Diaz-Flores, Ernesto;Hentgen, Veronique;Greder-Belan, Alix;Azarian, Reza;Koukabi, Mehrsa;Rousselot, Philippe;Raggueneau, Victoria;Maneglier, Benjamin
10.1111/bjh.16943
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Rapid screening of COVID-19 patients using white blood cell scattergrams, a study on 381 patients. [Abstract]: Complementary tools are warranted to increase the sensitivity of the initial testing for COVID-19. We identified a specific 'sandglass' aspect on the white blood cell scattergram of COVID-19 patients ...
32,409,210
J Clin Neurosci
Coexistence of COVID-19 and acute ischemic stroke report of four cases.
Coronaviruses are revealed to target the human respiratory system mainly. However, they also have neuro-invasive abilities and might spread from the respiratory system to the central nervous system. Herein, we report four patients with COVID-19 simultaneously diagnosed with acute ischemic stroke. There were four stroke...
covid-19;coronavirus;ischemia;stroke
Case Reports
TunC, Abdulkadir;UnlUbaS, Yonca;Alemdar, Murat;AkyUz, Enes
10.1016/j.jocn.2020.05.018
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Coexistence of COVID-19 and acute ischemic stroke report of four cases. [Abstract]: Coronaviruses are revealed to target the human respiratory system mainly. However, they also have neuro-invasive abilities and might spread from the respiratory system to the central nervous system. Herein, we report four patie...
32,918,466
Clin Infect Dis
Infectious Diseases Society of America Guidelines on the Diagnosis of COVID-19:Serologic Testing.
BACKGROUND: The availability of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serologic testing has rapidly increased. Current assays use a variety of technologies, measure different classes of immunoglobulin or immunoglobulin combinations and detect antibodies directed against different portions of the ...
Journal Article
Hanson, Kimberly E;Caliendo, Angela M;Arias, Cesar A;Englund, Janet A;Hayden, Mary K;Lee, Mark J;Loeb, Mark;Patel, Robin;Altayar, Osama;El Alayli, Abdallah;Sultan, Shahnaz;Falck-Ytter, Yngve;Lavergne, Valery;Morgan, Rebecca L;Murad, M Hassan;Bhimraj, Adarsh;Mustafa, Reem A
10.1093/cid/ciaa1343
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Infectious Diseases Society of America Guidelines on the Diagnosis of COVID-19:Serologic Testing. [Abstract]: BACKGROUND: The availability of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serologic testing has rapidly increased. Current assays use a variety of technologies, measure different cla...
32,657,710
S Afr Med J
COVID-19 and tuberculosis in South Africa: A dangerous combination.
There has been much speculation during the past week about the catastrophe that awaits once coronavirus disease 2019 (COVID-19) establishes itself in the poorest communities of South Africa (SA) and, importantly, in informal settlements. Evidence to date suggests that COVID-19 is efficiently passed from infected indivi...
Letter
Boffa, J;Mhlaba, T;Sulis, G;Moyo, S;Sifumba, Z;Pai, M;Daftary, A
10.7196/SAMJ.2020.v110i5.14747
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 and tuberculosis in South Africa: A dangerous combination. [Abstract]: There has been much speculation during the past week about the catastrophe that awaits once coronavirus disease 2019 (COVID-19) establishes itself in the poorest communities of South Africa (SA) and, importantly, in informal settle...
32,692,464
Hepatology
Elevated Liver Biochemistries in Hospitalized Chinese Patients with Severe COVID-19: Systematic Review and Meta-analysis.
BACKGROUND & AIMS: Several recent studies have reported an abnormal liver chemistry profile among patients with coronavirus disease 2019 (COVID-19), although its clinical significance remains unknown. APPROACH & RESULTS: This novel systematic review and meta-analysis identified six studies of 586 patients delineating l...
Journal Article
Kovalic, Alexander J;Huang, Glen;Thuluvath, Paul J;Satapathy, Sanjaya K
10.1002/hep.31472
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Elevated Liver Biochemistries in Hospitalized Chinese Patients with Severe COVID-19: Systematic Review and Meta-analysis. [Abstract]: BACKGROUND & AIMS: Several recent studies have reported an abnormal liver chemistry profile among patients with coronavirus disease 2019 (COVID-19), although its clinical signif...
32,696,862
Rev Assoc Med Bras (1992)
Use of remdesivir for patients with Covid-19: a review article.
The etiological agent of COVID-19, which causes severe respiratory diseases such as pneumonia and pulmonary insufficiency, has been confirmed as a new coronavirus, now known as Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). There is currently no authorized medication for the treatment of COVID-19. No vac...
Journal Article;Review
Azevedo, Thomas Cavalcanti Pires de;Azevedo, Pedro Cavalcanti Pires de;Silveira Filho, Robson Natario;Carvalho, Arthur Ricardo Vilar Scavuzzi de;Cezarotti Filho, Murilo Lobo;Barbosa, Fabiano Timbo;Sousa-Rodrigues, Celio Fernando de;Matos-Rocha, Thiago Jose;Ramos, Fernando Wagner da Silva
10.1590/1806-9282.66.6.838
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Use of remdesivir for patients with Covid-19: a review article. [Abstract]: The etiological agent of COVID-19, which causes severe respiratory diseases such as pneumonia and pulmonary insufficiency, has been confirmed as a new coronavirus, now known as Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-...
32,929,715
Acta Anaesthesiol Scand
Characteristics, interventions, and longer term outcomes of COVID-19 ICU patients in Denmark-A nationwide, observational study.
BACKGROUND: Most data on intensive care unit (ICU) patients with COVID-19 originate in selected populations from stressed healthcare systems with shorter term follow-up. We present characteristics, interventions and longer term outcomes of the entire, unselected cohort of all ICU patients with COVID-19 in Denmark where...
covid-19;sars-cov-2;comorbidities;intensive care;mortality
Journal Article;Observational Study
Haase, Nicolai;Plovsing, Ronni;Christensen, Steffen;Poulsen, Lone Musaeus;Brochner, Anne Craveiro;Rasmussen, Bodil Steen;Helleberg, Marie;Jensen, Jens Ulrik Staehr;Andersen, Lars Peter Kloster;Siegel, Hanna;Ibsen, Michael;Jorgensen, Vibeke;Winding, Robert;Iversen, Susanne;Pedersen, Henrik Planck;Madsen, Jacob;Solling, ...
10.1111/aas.13701
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Characteristics, interventions, and longer term outcomes of COVID-19 ICU patients in Denmark-A nationwide, observational study. [Abstract]: BACKGROUND: Most data on intensive care unit (ICU) patients with COVID-19 originate in selected populations from stressed healthcare systems with shorter term follow-up. W...
32,608,513
Int J Gynaecol Obstet
Coronavirus disease 2019: Knowledge, attitude, and practice of pregnant women in a tertiary hospital in Abakaliki, southeast Nigeria.
OBJECTIVE: To determine the knowledge, attitude, and practice of antenatal attendees towards COVID-19 in Alex Ekwueme Federal University Teaching Hospital, Abakaliki, Nigeria. METHODS: A cross-sectional survey was carried out among 430 consenting pregnant women attending antenatal clinics between March 1 and May 30, 20...
abakaliki;covid-19;chloroquine;knowledge;nigeria;pregnancy
Journal Article
Anikwe, Chidebe C;Ogah, Christian O;Anikwe, Ifeyinwa H;Okorochukwu, Bartholomew C;Ikeoha, Cyril C
10.1002/ijgo.13293
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Coronavirus disease 2019: Knowledge, attitude, and practice of pregnant women in a tertiary hospital in Abakaliki, southeast Nigeria. [Abstract]: OBJECTIVE: To determine the knowledge, attitude, and practice of antenatal attendees towards COVID-19 in Alex Ekwueme Federal University Teaching Hospital, Abakaliki...
32,904,955
J Am Coll Emerg Physicians Open
Transthoracic echocardiography during prone position ventilation: Lessons from the COVID-19 pandemic.
Objective: The current coronavirus disease 2019 (COVID-19 outbreak) demands an increased need for hospitalizations in emergency departments (EDs) and critical care units. Owing to refractory hypoxemia, prone position ventilation has been used more frequently and patients will need repeated hemodynamic assessments. Our ...
echocardiography;mechanical ventilation;prone position
Journal Article
Garcia-Cruz, Edgar;Manzur-Sandoval, Daniel;Gopar-Nieto, Rodrigo;Murillo-Ochoa, Adriana L;Bejarano-Alva, Gabriela;Rojas-Velasco, Gustavo;Alvarez-Alvarez, Rolando J;Baranda-Tovar, Francisco
10.1002/emp2.12239
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Transthoracic echocardiography during prone position ventilation: Lessons from the COVID-19 pandemic. [Abstract]: Objective: The current coronavirus disease 2019 (COVID-19 outbreak) demands an increased need for hospitalizations in emergency departments (EDs) and critical care units. Owing to refractory hypoxe...
33,010,706
Biosens Bioelectron
An integrated system of air sampling and simultaneous enrichment for rapid biosensing of airborne coronavirus and influenza virus.
Point-of-care risk assessment (PCRA) for airborne viruses requires a system that can enrich low-concentration airborne viruses dispersed in field environments into a small volume of liquid. In this study, airborne virus particles were collected to a degree above the limit of detection (LOD) for a real-time quantitative...
aerosol-to-hydrosol sampling;airborne virus;airborne virus monitoring;coronavirus;electrostatic air sampler;virus enrichment
Journal Article
Kim, Hyeong Rae;An, Sanggwon;Hwang, Jungho
10.1016/j.bios.2020.112656
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: An integrated system of air sampling and simultaneous enrichment for rapid biosensing of airborne coronavirus and influenza virus. [Abstract]: Point-of-care risk assessment (PCRA) for airborne viruses requires a system that can enrich low-concentration airborne viruses dispersed in field environments into a sm...
32,197,085
Curr Biol
Probable Pangolin Origin of SARS-CoV-2 Associated with the COVID-19 Outbreak.
An outbreak of coronavirus disease 2019 (COVID-19) caused by the 2019 novel coronavirus (SARS-CoV-2) began in the city of Wuhan in China and has widely spread worldwide. Currently, it is vital to explore potential intermediate hosts of SARS-CoV-2 to control COVID-19 spread. Therefore, we reinvestigated published data f...
covid-19;sars-cov-2;origin;pangolin
Journal Article;Research Support, Non-U.S. Gov't
Zhang, Tao;Wu, Qunfu;Zhang, Zhigang
10.1016/j.cub.2020.03.022
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Probable Pangolin Origin of SARS-CoV-2 Associated with the COVID-19 Outbreak. [Abstract]: An outbreak of coronavirus disease 2019 (COVID-19) caused by the 2019 novel coronavirus (SARS-CoV-2) began in the city of Wuhan in China and has widely spread worldwide. Currently, it is vital to explore potential interme...
32,534,509
Iran J Allergy Asthma Immunol
Management of COVID-19 Virus Infection by Convalescent Plasma.
No Abstract.
no keywords
Letter
Cheraghali, Abdol Majid;Abolghasemi, Hassan;Eshghi, Peyman
10.18502/ijaai.v19i(s1.r1).2847
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Management of COVID-19 Virus Infection by Convalescent Plasma. [Abstract]: No Abstract. [Keywords]: no keywords
32,854,742
Ital J Pediatr
Kawasaki disease epidemic: pitfalls.
Recent reports have described in the pediatric population a new type of hyperinflammatory response manifested following contact with SARS-CoV-2, with some of the clinical features attributable to Kawasaki disease (KD). The purpose of this commentary is to remark on a possible recent association between SARS-CoV-2 and K...
hyperinflammatory response;kawasaki disease;pediatric population;sars-cov-2
Journal Article
Gallizzi, Romina;Corsello, Giovanni;Pajno, Giovanni Battista
10.1186/s13052-020-00887-4
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Kawasaki disease epidemic: pitfalls. [Abstract]: Recent reports have described in the pediatric population a new type of hyperinflammatory response manifested following contact with SARS-CoV-2, with some of the clinical features attributable to Kawasaki disease (KD). The purpose of this commentary is to remark...
32,705,604
Drugs
Is Acetylsalicylic Acid a Safe and Potentially Useful Choice for Adult Patients with COVID-19 ?
Severe Acute Respiratory Syndrome-Coronavirus-2 is responsible for the current pandemic that has led to more than 10 million confirmed cases of Coronavirus Disease-19 (COVID-19) and over 500,000 deaths worldwide (4 July 2020). Virus-mediated injury to multiple organs, mainly the respiratory tract, activation of immune ...
Journal Article;Review
Bianconi, Vanessa;Violi, Francesco;Fallarino, Francesca;Pignatelli, Pasquale;Sahebkar, Amirhossein;Pirro, Matteo
10.1007/s40265-020-01365-1
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Is Acetylsalicylic Acid a Safe and Potentially Useful Choice for Adult Patients with COVID-19 ? [Abstract]: Severe Acute Respiratory Syndrome-Coronavirus-2 is responsible for the current pandemic that has led to more than 10 million confirmed cases of Coronavirus Disease-19 (COVID-19) and over 500,000 deaths w...
32,827,186
J Card Surg
COVID-19 infection in left ventricular assist device patients.
We describe two cases of favorable and unexpected recovery in positive patients with coronavirus disease 2019, suffering from multiorgan comorbidity and already assisted with the left ventricular assist device. We have observed that, although in the presence of more comorbidities, when the maintenance of a valid suppor...
cardiovascular pathology;cardiovascular research
Case Reports
Piperata, Antonio;Bottio, Tomaso;Gerosa, Gino
10.1111/jocs.14969
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: COVID-19 infection in left ventricular assist device patients. [Abstract]: We describe two cases of favorable and unexpected recovery in positive patients with coronavirus disease 2019, suffering from multiorgan comorbidity and already assisted with the left ventricular assist device. We have observed that, al...
32,549,587
Biol Conserv
COVID-19 pandemic and associated lockdown as a "Global Human Confinement Experiment" to investigate biodiversity conservation.
Efforts to curtail the spread of the novel coronavirus (SARS-CoV2) have led to the unprecedented concurrent confinement of nearly two-thirds of the global population. The large human lockdown and its eventual relaxation can be viewed as a Global Human Confinement Experiment. This experiment is a unique opportunity to i...
covid-19;human impacts;protected areas;sustainability;wildlife
Journal Article;Review
Bates, Amanda E;Primack, Richard B;Moraga, Paula;Duarte, Carlos M
10.1016/j.biocon.2020.108665
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 pandemic and associated lockdown as a "Global Human Confinement Experiment" to investigate biodiversity conservation. [Abstract]: Efforts to curtail the spread of the novel coronavirus (SARS-CoV2) have led to the unprecedented concurrent confinement of nearly two-thirds of the global population. The l...
32,551,773
Psychol Trauma
The rise of adverse childhood experiences during the COVID-19 pandemic.
Adverse childhood experiences, which is defined by different forms of abuse, neglect, and household dysfunction occurring before the age of 18 years, is a major public health problem in the United States that has the potential to worsen in the current COVID-19 pandemic. Moreover, the challenge is even greater for child...
Journal Article
Bryant, Daniel J;Oo, May;Damian, April Joy
10.1037/tra0000711
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The rise of adverse childhood experiences during the COVID-19 pandemic. [Abstract]: Adverse childhood experiences, which is defined by different forms of abuse, neglect, and household dysfunction occurring before the age of 18 years, is a major public health problem in the United States that has the potential ...
32,541,471
Medicine (Baltimore)
Withdrawing mycophenolate mofetil in treating a young kidney transplant recipient with COVID-19: A case report.
RATIONALE: Coronavirus disease 2019 (COVID-19) is a novel infectious disease and became a global issue. Treatment of COVID-19 especially in solid organ transplant recipients is empirical and controversial, especially the adjustment of the immunosuppressants. PATIENT CONCERNS: A 29-year-old kidney transplant recipient w...
Case Reports;Journal Article
Chen, Dong;Yang, Bo;Zhang, Yan;Chen, Liang;Wei, Lai;Zhang, Weijie;Wang, Xinqiang;Tong, Xiaolin;Chen, Zhishui
10.1097/MD.0000000000020481
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Withdrawing mycophenolate mofetil in treating a young kidney transplant recipient with COVID-19: A case report. [Abstract]: RATIONALE: Coronavirus disease 2019 (COVID-19) is a novel infectious disease and became a global issue. Treatment of COVID-19 especially in solid organ transplant recipients is empirical ...
32,837,095
J Clin Exp Hepatol
Gastrointestinal and Hepatic Involvement in Severe Acute Respiratory Syndrome Coronavirus 2 Infection: A Review.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has caused a pandemic coronavirus disease-19 (COVID-19) that began in Wuhan city, China, in December 2019. Till 14th April, 19,39,801 people have been affected by this virus, of whom 1,20,897 died. Though respiratory symptoms are the typical manifes...
ace2, angiotensin receptor 2;ci, confidence interval;covid-19, coronavirus disease-19;gi, gastrointestinal;rna, ribonucleic acid;rt-pcr, real-time polymerase chain reaction;sars-cov-2, severe acute respiratory syndrome coronavirus 2;tmprss, transmembrane serine protease;betacoronavirus;coronavirus disease-19;diarrhea;h...
Journal Article;Review
Ghoshal, Uday C;Ghoshal, Ujjala;Dhiman, Radha K
10.1016/j.jceh.2020.06.002
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Gastrointestinal and Hepatic Involvement in Severe Acute Respiratory Syndrome Coronavirus 2 Infection: A Review. [Abstract]: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has caused a pandemic coronavirus disease-19 (COVID-19) that began in Wuhan city, China, in December 2019. Till 14t...
32,363,337
Am J Obstet Gynecol MFM
Severe acute respiratory distress syndrome in coronavirus disease 2019-infected pregnancy: obstetric and intensive care considerations.
Since the emergence of a novel coronavirus (severe acute respiratory syndrome coronavirus 2) in Wuhan, China, at the end of December 2019, coronavirus disease 2019 has been associated with severe morbidity and mortality and has left world governments, healthcare systems, and providers caring for vulnerable populations,...
ards;covid-19;acute sars-cov-2;coronavirus;pneumonia;pregnancy;respiratory distress syndrome
Case Reports;Journal Article
Schnettler, William T;Al Ahwel, Yousef;Suhag, Anju
10.1016/j.ajogmf.2020.100120
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Severe acute respiratory distress syndrome in coronavirus disease 2019-infected pregnancy: obstetric and intensive care considerations. [Abstract]: Since the emergence of a novel coronavirus (severe acute respiratory syndrome coronavirus 2) in Wuhan, China, at the end of December 2019, coronavirus disease 2019...
32,576,313
Disaster Med Public Health Prep
A Proposed COVID-19 Testing Algorithm.
The 2019 coronavirus disease (COVID-19) pandemic has led to physical distancing measures in numerous countries in an attempt to control the spread. However, these measures are not without cost to the health and economies of the nations in which they are enacted. Nations are now looking for methods to remove physical di...
communicable diseases;epidemiological monitoring;pandemics;policy making;public health
Journal Article
Hart, Alexander;Bortolin, Michelangelo;Awoniyi, Oluwafunbi;Alhajjaj, Fahad;Ciottone, Gregory R
10.1017/dmp.2020.218
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: A Proposed COVID-19 Testing Algorithm. [Abstract]: The 2019 coronavirus disease (COVID-19) pandemic has led to physical distancing measures in numerous countries in an attempt to control the spread. However, these measures are not without cost to the health and economies of the nations in which they are enacte...
32,499,154
Arch Med Res
Covid-19 Pandemic and Current Medical Interventions.
First humanoid coronavirus was discovered in the middle of 1960s, the class of viruses are considered to be a huge threat. The first onset of human coronavirus, SARS (SARS-CoV) appeared in 2003 which spanned five continents having lethal effects on human population accompanied by The Middle East Respiratory Syndrome Co...
human coronavirus;sars-cov2;structure;therapy;treatments;virus
Journal Article;Review
Manhas, Sweeta;Anjali, Anjali;Mansoor, Sheikh;Sharma, Vikas;Ahmad, Ajaz;Rehman, Muneeb U;Ahmad, Parvaiz
10.1016/j.arcmed.2020.05.007
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Covid-19 Pandemic and Current Medical Interventions. [Abstract]: First humanoid coronavirus was discovered in the middle of 1960s, the class of viruses are considered to be a huge threat. The first onset of human coronavirus, SARS (SARS-CoV) appeared in 2003 which spanned five continents having lethal effects ...
32,454,232
J Vasc Surg
Experience from a Singapore tertiary hospital with restructuring of a vascular surgery practice in response to national and institutional policies during the COVID-19 pandemic.
Singapore was one of the first countries to be affected by COVID-19, with the index patient diagnosed on January 23, 2020. For 2 weeks in February, we had the highest number of COVID-19 cases behind China. In this article, we summarize the key national and institutional policies that were implemented in response to COV...
covid-19;coronavirus disease 2019;segregation;surgical practice;vascular surgery
Journal Article
Ng, Jun Jie;Gan, Tiffany R X;Niam, Jen Yong;Menon, Raj K;Ho, Pei;Dharmaraj, Rajesh B;Wong, Julian C L;Choong, Andrew M T L
10.1016/j.jvs.2020.05.026
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Experience from a Singapore tertiary hospital with restructuring of a vascular surgery practice in response to national and institutional policies during the COVID-19 pandemic. [Abstract]: Singapore was one of the first countries to be affected by COVID-19, with the index patient diagnosed on January 23, 2020....
33,075,144
Allergy
Management of patients with chronic rhinosinusitis during the COVID-19 pandemic - An EAACI Position Paper.
BACKGROUND: CRS is regarded as a chronic airway disease. According to WHO recommendations, it may be a risk factor for COVID-19 patients. In most CRSwNP cases, the inflammatory changes affecting the nasal and paranasal mucous membranes are type-2 (T2) inflammation endotypes. METHODS: The current knowledge on COVID-19 a...
biologics;covid-19;crswnp;chronic rhinosinusitis;dupilumab;sars cov-2;intranasal corticosteroids;nasal polyps
Journal Article
Klimek, L;Jutel, M;Bousquet, J;Agache, I;Akdis, C;Hox, V;Gevaert, P;Tomazic, P V;Rondon, C;Cingi, C;Toppila-Salmi, S;Karavelia, A;Bozkurt, B;Forster-Ruhrmann, U;Becker, S;Chaker, A M;Wollenberg, B;Mosges, R;Huppertz, T;Hagemann, J;Bachert, C;Fokkens, W
10.1111/all.14629
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Management of patients with chronic rhinosinusitis during the COVID-19 pandemic - An EAACI Position Paper. [Abstract]: BACKGROUND: CRS is regarded as a chronic airway disease. According to WHO recommendations, it may be a risk factor for COVID-19 patients. In most CRSwNP cases, the inflammatory changes affecti...
33,030,379
Br J Community Nurs
A point-of-care app for chronic oedema management.
The COVID-19 pandemic of 2020 has led to considerable changes in how healthcare is delivered, as it has pushed people to think outside the box technologically. Mobile working is becoming more widespread, useful and valuable in this innovative period in the NHS. Point-of-care (POC) technology encompasses mobile devices ...
chronic oedema;lymphoedema;mobile app;point-of-care technology;self-care
Journal Article
Collett, Mercita
10.12968/bjcn.2020.25.Sup10.S12
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: A point-of-care app for chronic oedema management. [Abstract]: The COVID-19 pandemic of 2020 has led to considerable changes in how healthcare is delivered, as it has pushed people to think outside the box technologically. Mobile working is becoming more widespread, useful and valuable in this innovative perio...
32,498,413
Antibiotics (Basel)
Anti-Infectious Plants of The Thai Karen: A Meta-Analysis.
Pharmacology has developed many drugs to treat infections, but many people, especially in developing countries, cannot afford to purchase them, and still depend on traditional knowledge and local medicinal plants to fight off infections. In addition, numerous microbes have developed resistance to the pharmaceutical dru...
cleidion javanicum;litsea cubeba;tinospora crispa;antimicrobial;bacterial;ethnobotany;ethnomedicinal plants;fungal;infectious diseases;viral
Journal Article
Phumthum, Methee;Balslev, Henrik
10.3390/antibiotics9060298
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Anti-Infectious Plants of The Thai Karen: A Meta-Analysis. [Abstract]: Pharmacology has developed many drugs to treat infections, but many people, especially in developing countries, cannot afford to purchase them, and still depend on traditional knowledge and local medicinal plants to fight off infections. In...
33,066,801
Crit Care
SARS-CoV-2 detection in the lower respiratory tract of invasively ventilated ARDS patients.
BACKGROUND: Data on SARS-CoV-2 load in lower respiratory tract (LRT) are scarce. Our objectives were to describe the viral shedding and the viral load in LRT and to determine their association with mortality in critically ill COVID-19 patients. METHODS: We conducted a binational study merging prospectively collected da...
covid-19;icu;lower respiratory tract;mortality;sars-cov-2;viral load;viral shedding
Journal Article;Research Support, Non-U.S. Gov't
Buetti, Niccolo;Wicky, Paul-Henri;Le Hingrat, Quentin;Ruckly, Stephane;Mazzuchelli, Timothy;Loiodice, Ambre;Trimboli, Pierpaolo;Forni Ogna, Valentina;de Montmollin, Etienne;Bernasconi, Enos;Visseaux, Benoit;Timsit, Jean-Francois
10.1186/s13054-020-03323-5
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: SARS-CoV-2 detection in the lower respiratory tract of invasively ventilated ARDS patients. [Abstract]: BACKGROUND: Data on SARS-CoV-2 load in lower respiratory tract (LRT) are scarce. Our objectives were to describe the viral shedding and the viral load in LRT and to determine their association with mortality...
32,870,469
Endocrine
Diabetes mellitus is a risk factor for prolonged SARS-CoV-2 viral shedding in lower respiratory tract samples of critically ill patients.
PURPOSE: The length of time a critically ill coronavirus disease 2019 (COVID-19) patient remains infectious and should therefore be isolated remains unknown. This prospective study was undertaken in critically ill patients to evaluate the reliability of single negative real-time polymerase chain reaction (RT-PCR) in lo...
covid-19;infectivity;intensive care unit;sars-cov-2;type 2 diabetes mellitus;viral shedding
Journal Article;Research Support, Non-U.S. Gov't
Buetti, Niccolo;Trimboli, Pierpaolo;Mazzuchelli, Timothy;Lo Priore, Elia;Balmelli, Carlo;Trkola, Alexandra;Conti, Marco;Martinetti, Gladys;Elzi, Luigia;Ceschi, Alessandro;Consonni, Vera;Ogna, Adam;Forni-Ogna, Valentina;Bernasconi, Enos
10.1007/s12020-020-02465-4
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Diabetes mellitus is a risk factor for prolonged SARS-CoV-2 viral shedding in lower respiratory tract samples of critically ill patients. [Abstract]: PURPOSE: The length of time a critically ill coronavirus disease 2019 (COVID-19) patient remains infectious and should therefore be isolated remains unknown. Thi...
32,522,738
BMJ Glob Health
Community health workers for pandemic response: a rapid evidence synthesis.
INTRODUCTION: Coronavirus disease (COVID-19), affects 213 countries or territories globally. We received a request from National Health Systems Resource Centre, a public agency in India, to conduct rapid evidence synthesis (RES) on community health workers (CHWs) for COVID-19 prevention and control in 3 days. METHODS: ...
health services research;health systems;infections, diseases, disorders, injuries;systematic review
Journal Article;Research Support, Non-U.S. Gov't;Systematic Review
Bhaumik, Soumyadeep;Moola, Sandeep;Tyagi, Jyoti;Nambiar, Devaki;Kakoti, Misimi
10.1136/bmjgh-2020-002769
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Community health workers for pandemic response: a rapid evidence synthesis. [Abstract]: INTRODUCTION: Coronavirus disease (COVID-19), affects 213 countries or territories globally. We received a request from National Health Systems Resource Centre, a public agency in India, to conduct rapid evidence synthesis ...
32,652,095
Chest
Addressing Reduced Laboratory-Based Pulmonary Function Testing During a Pandemic.
To reduce the spread of the severe acute respiratory syndrome coronavirus 2, many pulmonary function testing (PFT) laboratories have been closed or have significantly reduced their testing capacity. Because these mitigation strategies may be necessary for the next 6 to 18 months to prevent recurrent peaks in disease pr...
copd;covid-19 pandemic;sars-cov-2;asthma;pulmonary function test;review
Journal Article;Review
Kouri, Andrew;Gupta, Samir;Yadollahi, Azadeh;Ryan, Clodagh M;Gershon, Andrea S;To, Teresa;Tarlo, Susan M;Goldstein, Roger S;Chapman, Kenneth R;Chow, Chung-Wai
10.1016/j.chest.2020.06.065
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Addressing Reduced Laboratory-Based Pulmonary Function Testing During a Pandemic. [Abstract]: To reduce the spread of the severe acute respiratory syndrome coronavirus 2, many pulmonary function testing (PFT) laboratories have been closed or have significantly reduced their testing capacity. Because these miti...
33,028,699
BMJ Glob Health
Lockdown measures in response to COVID-19 in nine sub-Saharan African countries.
Lockdown measures have been introduced worldwide to contain the transmission of COVID-19. However, the term 'lockdown' is not well-defined. Indeed, WHO's reference to 'so-called lockdown measures' indicates the absence of a clear and universally accepted definition of the term 'lockdown'. We propose a definition of 'lo...
sars
Journal Article;Research Support, Non-U.S. Gov't;Review
Haider, Najmul;Osman, Abdinasir Yusuf;Gadzekpo, Audrey;Akipede, George O;Asogun, Danny;Ansumana, Rashid;Lessells, Richard John;Khan, Palwasha;Hamid, Muzamil Mahdi Abdel;Yeboah-Manu, Dorothy;Mboera, Leonard;Shayo, Elizabeth Henry;Mmbaga, Blandina T;Urassa, Mark;Musoke, David;Kapata, Nathan;Ferrand, Rashida Abbas;Kapata,...
10.1136/bmjgh-2020-003319
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Lockdown measures in response to COVID-19 in nine sub-Saharan African countries. [Abstract]: Lockdown measures have been introduced worldwide to contain the transmission of COVID-19. However, the term 'lockdown' is not well-defined. Indeed, WHO's reference to 'so-called lockdown measures' indicates the absence...
32,896,863
J Rehabil Med
Insights from an interprofessional post-COVID-19 rehabilitation unit: A speech and language therapy and respiratory medicine perspective.
OBJECTIVE: We present a case report that complements the conclusion of Stam et al. in their call to rehabilitation facilities to anticipate and prepare to address post intensive care syndrome in post-Covid-19 patients. METHODS: The case report presented here provides insight into treating mechanically ventilated post-C...
covid-19;post intensive care syndrome;rehabilitation;speaking valve;speech and language therapy;swallowing;tracheostomy management
Case Reports;Journal Article
Stierli, Sarah;Buss, Irene;Redecker, Hermann;Baumberger, Michael;Blattler, Erika;Selb, Melissa;Hinter, Sandra;Ischer, Barbara;Schwegler, Hans
10.2340/16501977-2735
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Insights from an interprofessional post-COVID-19 rehabilitation unit: A speech and language therapy and respiratory medicine perspective. [Abstract]: OBJECTIVE: We present a case report that complements the conclusion of Stam et al. in their call to rehabilitation facilities to anticipate and prepare to addres...
32,926,713
Clin Pract Cases Emerg Med
Crazy-Paving: A Computed Tomographic Finding of Coronavirus Disease 2019.
INTRODUCTION: Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2. COVID-19 first occurred in Wuhan, China, in December 2019, and by March 2020 COVID-19 was declared a global pandemic. CASE PRESENTATION: We describe a case of a 52-year-old female with past medical history of...
Journal Article
Gillespie, Megan;Flannery, Patrick;Schumann, Jessica A;Dincher, Nathan;Mills, Rebecca;Can, Argun
10.5811/cpcem.2020.5.47998
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Crazy-Paving: A Computed Tomographic Finding of Coronavirus Disease 2019. [Abstract]: INTRODUCTION: Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2. COVID-19 first occurred in Wuhan, China, in December 2019, and by March 2020 COVID-19 was declared a global pande...
32,874,688
Curr Health Sci J
COVID-19 and Management of Severe Acute Respiratory Infection (SARI): A Questionnaire-Based Study Among Indian Healthcare Professionals.
BACKGROUND: COVID-19 presenting as SARI (severe acute respiratory syndrome) mandates the need for ICU (intensive care unit) hospitalization, increasing healthcare burden. This study aims to determine knowledge of healthcare professionals towards management of SARI in COVID-19 suspected cases. METHODS: A total of 313 he...
covid-19;covid-19 india;sari;severe acute respiratory infection;who guidelines for covid-19 related sari
Journal Article
Patankar, Ashwini;Modi, Pranav;Uppe, Abhay;Tuppekar, Balaji;Chandrakar, Santwana;Nair, Girija;Patil, Surekha;Langade, Deepak
10.12865/CHSJ.46.02.09
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 and Management of Severe Acute Respiratory Infection (SARI): A Questionnaire-Based Study Among Indian Healthcare Professionals. [Abstract]: BACKGROUND: COVID-19 presenting as SARI (severe acute respiratory syndrome) mandates the need for ICU (intensive care unit) hospitalization, increasing healthcare...