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32,302,722
J Hosp Infect
Clinical characteristics of 80 hospitalized frontline medical workers infected with COVID-19 in Wuhan, China.
More than 1,000 medical workers have been infected with COVID-19 in China. The 80 hospitalized patients included 57 SARS-CoV-2 confirmed and 23 clinically diagnosed. The median age was 39 years, 49 (61.25%) were women, and one patient died. The most common symptoms at onset were fever (65, 81.25%), cough (47, 58.75%), ...
covid-19;sars-cov-2;medical worker;outcome;treatment
Journal Article
Wang, Xiong;Liu, Wei;Zhao, Jinzhu;Lu, Yanjun;Wang, Xu;Yu, Caizheng;Hu, Shuhua;Shen, Na;Liu, Weiyong;Sun, Ziyong;Li, Wengang
10.1016/j.jhin.2020.04.019
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical characteristics of 80 hospitalized frontline medical workers infected with COVID-19 in Wuhan, China. [Abstract]: More than 1,000 medical workers have been infected with COVID-19 in China. The 80 hospitalized patients included 57 SARS-CoV-2 confirmed and 23 clinically diagnosed. The median age was 39 y...
32,815,344
Tidsskr Nor Laegeforen
Ventilatory support for hypoxaemic intensive care patients with COVID-19.
BACKGROUND: COVID-19 pneumonia can result in severe hypoxaemic respiratory failure that requires intensive medical care. We wished to describe COVID-19 intensive care patients who were treated with and without invasive ventilatory support. MATERIAL AND METHOD: The material was retrieved from the local quality register ...
Journal Article
Gundem, Trine;Olasveengen, Theresa Mariero;Hovda, Knut Erik;Gaustad, Knut;Schondorf, Christina;Rostrup, Morten;Froyshov, Sten;Undseth, Oystein;Tonby, Kristian;Holten, Aleksander Rygh;Sunde, Kjetil
10.4045/tidsskr.20.0445
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Ventilatory support for hypoxaemic intensive care patients with COVID-19. [Abstract]: BACKGROUND: COVID-19 pneumonia can result in severe hypoxaemic respiratory failure that requires intensive medical care. We wished to describe COVID-19 intensive care patients who were treated with and without invasive ventil...
32,779,744
J Med Virol
Analysis of the application value of serum antibody detection for staging of COVID-19 infection.
Coronavirus disease 2019 (COVID-19) has now spread all over the world. The National Health Commission of the People's Republic of China reported 78 439 cured and discharged cases, 4634 deaths, 83 462 confirmed cases and 760 818 close contacts as of 25 June 2020. Joint detection of nucleic acids and antibodies has becom...
ade effect;covid-19;sars-cov-2;infection stage;nucleic acid detection;serum antibody quantitative detection
Journal Article;Research Support, Non-U.S. Gov't
Zheng, Yutong;Yan, Meitian;Wang, Lan;Luan, Liang;Liu, Jing;Tian, Xiao;Wan, Nan
10.1002/jmv.26330
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Analysis of the application value of serum antibody detection for staging of COVID-19 infection. [Abstract]: Coronavirus disease 2019 (COVID-19) has now spread all over the world. The National Health Commission of the People's Republic of China reported 78 439 cured and discharged cases, 4634 deaths, 83 462 co...
32,360,182
Antiviral Res
Antiviral activities of type I interferons to SARS-CoV-2 infection.
There is an urgent need to identify antivirals to curtail the COVID-19 pandemic. Herein, we report the sensitivity of SARS-CoV-2 to recombinant human interferons alpha and beta (IFNalpha/beta). Treatment with IFN-alpha or IFN-beta at a concentration of 50 international units (IU) per milliliter reduces viral titers by ...
antiviral therapy;covid-19;innate immune;interferon;sars-cov-2
Journal Article
Mantlo, Emily;Bukreyeva, Natalya;Maruyama, Junki;Paessler, Slobodan;Huang, Cheng
10.1016/j.antiviral.2020.104811
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Antiviral activities of type I interferons to SARS-CoV-2 infection. [Abstract]: There is an urgent need to identify antivirals to curtail the COVID-19 pandemic. Herein, we report the sensitivity of SARS-CoV-2 to recombinant human interferons alpha and beta (IFNalpha/beta). Treatment with IFN-alpha or IFN-beta ...
32,876,719
HNO
[Quality of cochlear implant rehabilitation under COVID-19 conditions. German version].
BACKGROUND: The rehabilitation process following cochlear implant (CI) surgery is carried out in a multimodal therapy according to German national guidelines and includes technical and medical aftercare. In times of the corona pandemic surgery and rehabilitation appointments were cancelled or delayed leading to a more ...
aftercare;quality assurance;severe acute respiratory syndrome coronavirus 2;speech therapy;standard of care
Journal Article
Aschendorff, A;Arndt, S;Kroger, S;Wesarg, T;Ketterer, M C;Kirchem, P;Pixner, S;Hassepass, F;Beck, R
10.1007/s00106-020-00922-0
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [Quality of cochlear implant rehabilitation under COVID-19 conditions. German version]. [Abstract]: BACKGROUND: The rehabilitation process following cochlear implant (CI) surgery is carried out in a multimodal therapy according to German national guidelines and includes technical and medical aftercare. In time...
33,032,683
Skinmed
Sexually Transmitted Diseases in the COVID-19 Era.
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is an infectious disease of recent origin with high transmissibility and mortality. The resulting COVID-19 pandemic has impacted the United States the most, in terms of the number of confirmed cases and fatalities. How other aspects of public health will be i...
Journal Article;Review
Wiggins, Claire J;Rosen, Theodore
[ 0, 0, 1, 0, 1, 0, 0 ]
[Title]: Sexually Transmitted Diseases in the COVID-19 Era. [Abstract]: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is an infectious disease of recent origin with high transmissibility and mortality. The resulting COVID-19 pandemic has impacted the United States the most, in terms of the number of conf...
33,017,270
Telemed J E Health
Access to Care Matters: Remote Health Care Needs During COVID-19.
Background: The coronavirus disease 2019 (COVID-19) pandemic is straining health care worldwide with >31 million confirmed cases. Currently, 1 in every 100 U.S. residents and 245,000 in New York City are confirmed positive. The Bronx, with high-risk comorbidities, due in part to socioeconomic factors, has seen dispropo...
diversity;equity;health disparities;health policy;inclusion;medical ethics;structural and social determinants of health;telehealth;telemedicine
Journal Article
Vazquez, Juan;Islam, Tanzina;Gursky, Jonathan;Beller, Jennifer;Correa, Daniel Jose
10.1089/tmj.2020.0371
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Access to Care Matters: Remote Health Care Needs During COVID-19. [Abstract]: Background: The coronavirus disease 2019 (COVID-19) pandemic is straining health care worldwide with >31 million confirmed cases. Currently, 1 in every 100 U.S. residents and 245,000 in New York City are confirmed positive. The Bronx...
32,940,188
Rev Recent Clin Trials
Management of Idiopathic Intracranial Hypertension during the COVID19 Pandemic.
BACKGROUND: In the current coronavirus disease 2019 (COVID-19) pandemic, health systems are struggling to prioritize care for affected patients, however, physicians globally are also attempting to maintain care for other lessthreatening medical conditions that may lead to permanent disabilities if untreated. Idiopathic...
covid-19;cerebral venous sinus thrombosis;idiopathic intracranial hypertension;meningoencephalitis.;nonmydriatic fundus photography;optic nerve sheath fenestration;papillophlebitis
Journal Article
Elnahry, Ayman G;Elnahry, Gehad A
10.2174/1574887115666200917111413
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Management of Idiopathic Intracranial Hypertension during the COVID19 Pandemic. [Abstract]: BACKGROUND: In the current coronavirus disease 2019 (COVID-19) pandemic, health systems are struggling to prioritize care for affected patients, however, physicians globally are also attempting to maintain care for othe...
32,282,991
Am J Transplant
Immunosuppressive therapy maintenance in a kidney transplant recipient with SARS-CoV-2 pneumonia: A case report.
The role of systemic inflammation is proving crucial in determining unfavorable outcome in SARS-CoV-2-infected patients. Limited data are available regarding immunosuppression management in kidney transplant recipients (KTRs) with SARS-CoV-2 pneumonia. We report a case of a 32-year-old KTR who developed SARS-CoV-2 infe...
clinical research/practice;immunosuppressive regimens;infection and infectious agents-viral;kidney transplantation/nephrology
Case Reports
Bussalino, Elisabetta;De Maria, Andrea;Russo, Rodolfo;Paoletti, Ernesto
10.1111/ajt.15920
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Immunosuppressive therapy maintenance in a kidney transplant recipient with SARS-CoV-2 pneumonia: A case report. [Abstract]: The role of systemic inflammation is proving crucial in determining unfavorable outcome in SARS-CoV-2-infected patients. Limited data are available regarding immunosuppression management...
32,637,738
Am J Ophthalmol Case Rep
Absence of Severe Acute Respiratory Syndrome-Coronavirus-2 RNA in ocular tissues.
Purpose: To evaluate the status of ocular donor tissues of a COVID-19 postmortem donor. Methods: SARS-CoV-2 was detected via a pharyngeal swab and broncho-alveolar lavage in the COVID-19 suspect. Postmortem tissue procurement and preparation were performed with personal protective equipment (PPE) and the necessary prot...
covid-19;ophthalmological surgery;sars-cov-2;transplantation
Journal Article
Bayyoud, Tarek;Iftner, Angelika;Iftner, Thomas;Bartz-Schmidt, Karl Ulrich;Ueffing, Marius;Schindler, Michael;Thaler, Sebastian
10.1016/j.ajoc.2020.100805
[ 0, 0, 1, 0, 1, 0, 0 ]
[Title]: Absence of Severe Acute Respiratory Syndrome-Coronavirus-2 RNA in ocular tissues. [Abstract]: Purpose: To evaluate the status of ocular donor tissues of a COVID-19 postmortem donor. Methods: SARS-CoV-2 was detected via a pharyngeal swab and broncho-alveolar lavage in the COVID-19 suspect. Postmortem tissue pro...
32,905,833
Clin Microbiol Infect
Detection of severe acute respiratory syndrome coronavirus 2 in nasopharynx according to clinical phenotype of affected patients.
OBJECTIVES: Duration of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the upper respiratory tract is extremely variable, but its relation to disease severity is unknown. We investigated this relation in the 530 000 inhabitants of the northeastern Italian province of Udine. METHODS: We analysed real-ti...
coronavirus disease 2019;infectivity;nasopharyngeal swab;real-time rt-pcr;severe acute respiratory syndrome coronavirus 2
Journal Article
Valent, Francesca;Di Chiara, Antonio
10.1016/j.cmi.2020.08.041
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Detection of severe acute respiratory syndrome coronavirus 2 in nasopharynx according to clinical phenotype of affected patients. [Abstract]: OBJECTIVES: Duration of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the upper respiratory tract is extremely variable, but its relation to disease se...
32,620,022
Am J Perinatol
Universal SARS-Cov-2 Screening in Women Admitted for Delivery in a Large Managed Care Organization.
OBJECTIVE: The coronavirus disease 2019 (COVID-19) pandemic has created a need for data regarding the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in pregnant women. After implementing universal screening for COVID-19 in women admitted for delivery, we sought to describe the char...
Journal Article;Observational Study
Fassett, Michael J;Lurvey, Lawrence D;Yasumura, Lyn;Nguyen, Marielle;Colli, Joseph J;Volodarskiy, Marianna;Gullett, Jonathan C;Braun, David;Fong, Alex;Trivedi, Neha;Bruxvoort, Katia;Chiu, Vicki;Getahun, Darios
10.1055/s-0040-1714060
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: Universal SARS-Cov-2 Screening in Women Admitted for Delivery in a Large Managed Care Organization. [Abstract]: OBJECTIVE: The coronavirus disease 2019 (COVID-19) pandemic has created a need for data regarding the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in pregnant ...
33,064,125
Am J Health Syst Pharm
Association between opioid dose escalation and time to death in a comfort measures only population.
DISCLAIMER: In an effort to expedite the publication of articles related to the COVID-19 pandemic, AJHP is posting these manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manu...
death;end-of-life care;opioid;pain;pain management;palliative care
Journal Article
Abraham, Dana L;Hernandez, Inmaculada;Ayers, Gina T;Pruskowski, Jennifer A
10.1093/ajhp/zxaa367
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Association between opioid dose escalation and time to death in a comfort measures only population. [Abstract]: DISCLAIMER: In an effort to expedite the publication of articles related to the COVID-19 pandemic, AJHP is posting these manuscripts online as soon as possible after acceptance. Accepted manuscripts ...
32,837,910
J Orthop Translat
Impact of COVID-19 on orthopaedic clinical service, education and research in a university hospital.
The medical system of Hong Kong has been heavily affected by COVID-19. Adaptations are necessary to continue clinical care, education, and research, while minimising the risk of infection of our staff and students. Here, we report our early experience in response to the challenge posed by the COVID-19 pandemic. The tra...
covid-19;clinical service;education;orthopaedics;research
Journal Article;Review
Ong, Michael Tim-Yun;Ling, Samuel Ka-Kin;Wong, Ronald Man-Yeung;Ho, Kevin Ki-Wai;Chow, Simon Kwoon-Ho;Cheung, Louis Wing-Hoi;Yung, Patrick Shu-Hang
10.1016/j.jot.2020.08.001
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Impact of COVID-19 on orthopaedic clinical service, education and research in a university hospital. [Abstract]: The medical system of Hong Kong has been heavily affected by COVID-19. Adaptations are necessary to continue clinical care, education, and research, while minimising the risk of infection of our sta...
32,817,604
MMWR Morb Mortal Wkly Rep
Racial and Ethnic Disparities Among COVID-19 Cases in Workplace Outbreaks by Industry Sector - Utah, March 6-June 5, 2020.
Improved understanding of the overall distribution of workplace coronavirus disease 2019 (COVID-19) outbreaks by industry sector could help direct targeted public health action; however, this has not been described. The Utah Department of Health (UDOH) analyzed COVID-19 surveillance data to describe workplace outbreaks...
Journal Article
Bui, David P;McCaffrey, Keegan;Friedrichs, Michael;LaCross, Nathan;Lewis, Nathaniel M;Sage, Kylie;Barbeau, Bree;Vilven, Dede;Rose, Carolyn;Braby, Sara;Willardson, Sarah;Carter, Amy;Smoot, Christopher;Winquist, Andrea;Dunn, Angela
10.15585/mmwr.mm6933e3
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Racial and Ethnic Disparities Among COVID-19 Cases in Workplace Outbreaks by Industry Sector - Utah, March 6-June 5, 2020. [Abstract]: Improved understanding of the overall distribution of workplace coronavirus disease 2019 (COVID-19) outbreaks by industry sector could help direct targeted public health action...
32,533,585
Clin Cardiol
COVID-19 and the heart: An update for clinicians.
SARS-CoV-2, the cause of the COVID-19 pandemic has significantly impacted cardiovascular healthcare. Patients with pre-existing cardiovascular disease are at higher risk of morbidity and mortality. The virus may affect the heart directly and indirectly with clinical syndromes of acute myocardial injury, myocarditis, ac...
covid-19;nsaid;raas;acute myocardial injury;myocaritis
Journal Article;Review
Goha, Ahmed;Mezue, Kenechukwu;Edwards, Paul;Nunura, Felix;Baugh, Dainia;Madu, Ernest
10.1002/clc.23406
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: COVID-19 and the heart: An update for clinicians. [Abstract]: SARS-CoV-2, the cause of the COVID-19 pandemic has significantly impacted cardiovascular healthcare. Patients with pre-existing cardiovascular disease are at higher risk of morbidity and mortality. The virus may affect the heart directly and indirec...
32,532,950
Infez Med
Infection prevention and control in blood purification centers during the COVID-19 epidemic: a single institution experience from Zhejiang, China.
not available.
Journal Article
Yamei, Yang;Yanbo, Zhang;Yuhong, Jin;Xueyan, Bian
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Infection prevention and control in blood purification centers during the COVID-19 epidemic: a single institution experience from Zhejiang, China. [Abstract]: not available. [Keywords]:
32,561,681
J Am Soc Nephrol
Epidemiology of COVID-19 in an Urban Dialysis Center.
BACKGROUND: During the coronavirus disease 2019 (COVID-19) epidemic, many countries have instituted population-wide measures for social distancing. The requirement of patients on dialysis for regular treatment in settings typically not conducive to social distancing may increase their vulnerability to COVID-19. METHODS...
covid-19;clinical epidemiology;haemodialysis
Journal Article
Corbett, Richard W;Blakey, Sarah;Nitsch, Dorothea;Loucaidou, Marina;McLean, Adam;Duncan, Neill;Ashby, Damien R
10.1681/ASN.2020040534
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Epidemiology of COVID-19 in an Urban Dialysis Center. [Abstract]: BACKGROUND: During the coronavirus disease 2019 (COVID-19) epidemic, many countries have instituted population-wide measures for social distancing. The requirement of patients on dialysis for regular treatment in settings typically not conducive...
32,740,890
Stem Cell Rev Rep
Stem Cells Therapy as a Possible Therapeutic Option in Treating COVID-19 Patients.
An unfortunate emergence of a new virus SARS-CoV-2, causing a disease known as COVID-19, has spread all around the globe and has caused a pandemic. It primarily affects the respiratory tract and lungs in some cases causing severe organ damage and pneumonia due to overwhelming immune responses. Clinical reports show tha...
covid-19;immunomodulation;lymphocytes;mscs' immunomodulatory properties;mesenchymal stem cells (mscs);sars-cov-2
Journal Article;Review
Esquivel, Diana;Mishra, Rangnath;Soni, Prabhat;Seetharaman, Rajasekar;Mahmood, Anjum;Srivastava, Anand
10.1007/s12015-020-10017-6
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Stem Cells Therapy as a Possible Therapeutic Option in Treating COVID-19 Patients. [Abstract]: An unfortunate emergence of a new virus SARS-CoV-2, causing a disease known as COVID-19, has spread all around the globe and has caused a pandemic. It primarily affects the respiratory tract and lungs in some cases c...
33,076,848
BMC Infect Dis
The first consecutive 5000 patients with Coronavirus Disease 2019 from Qatar; a nation-wide cohort study.
BACKGROUND: There are limited data on Coronavirus Disease 2019 (COVID-19) outcomes at a national level, and none after 60 days of follow up. The aim of this study was to describe national, 60-day all-cause mortality associated with COVID-19, and to identify risk factors associated with admission to an intensive care un...
covid-19;coronavirus;mortality;qatar;sars-cov-2
Journal Article
Omrani, Ali S;Almaslamani, Muna A;Daghfal, Joanne;Alattar, Rand A;Elgara, Mohamed;Shaar, Shahd H;Ibrahim, Tawheeda B H;Zaqout, Ahmed;Bakdach, Dana;Akkari, Abdelrauof M;Baiou, Anas;Alhariri, Bassem;Elajez, Reem;Husain, Ahmed A M;Badawi, Mohamed N;Abid, Fatma Ben;Abu Jarir, Sulieman H;Abdalla, Shiema;Kaleeckal, Anvar;Cho...
10.1186/s12879-020-05511-8
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: The first consecutive 5000 patients with Coronavirus Disease 2019 from Qatar; a nation-wide cohort study. [Abstract]: BACKGROUND: There are limited data on Coronavirus Disease 2019 (COVID-19) outcomes at a national level, and none after 60 days of follow up. The aim of this study was to describe national, 60-d...
33,072,702
Front Public Health
Epidemiological and Genomic Analysis of SARS-CoV-2 in 10 Patients From a Mid-Sized City Outside of Hubei, China in the Early Phase of the COVID-19 Outbreak.
A novel coronavirus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the ongoing Coronavirus Disease 2019 (COVID-19) pandemic. In this study, we performed a comprehensive epidemiological and genomic analysis of SARS-CoV-2 genomes from 10 patients in Shaoxing (Zhejiang Province), a m...
2019-ncov;covid-19;sars-cov-2;genomic epidemiology;genotype;metagenomic sequencing;mutation rate;transmission
Journal Article
Chen, Jinkun;Hilt, Evann E;Li, Fan;Wu, Huan;Jiang, Zhuojing;Zhang, Qinchao;Wang, Jiling;Wang, Yifang;Li, Ziqin;Tang, Jialiang;Yang, Shangxin
10.3389/fpubh.2020.567621
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Epidemiological and Genomic Analysis of SARS-CoV-2 in 10 Patients From a Mid-Sized City Outside of Hubei, China in the Early Phase of the COVID-19 Outbreak. [Abstract]: A novel coronavirus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the ongoing Coronavirus Disease 2019...
32,621,858
Am J Infect Control
Resumption of respiratory outpatient services in the COVID-19 era: Experience from Southern Italy.
COVID-19 pandemic turned the entire health-care system organization upside-down, suspending elective activities and outpatient services. In Italy, we are entering a second phase of the pandemic and several strategies have been developed to "re-open" the country, some businesses, and also health care outpatient activiti...
novel coronavirus 2019;outpatient clinic;pulmonary function test;safety
Journal Article
Crimi, Claudia;Impellizzeri, Pietro;Campisi, Raffaele;Spicuzza, Lucia;Vancheri, Carlo;Crimi, Nunzio
10.1016/j.ajic.2020.06.210
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Resumption of respiratory outpatient services in the COVID-19 era: Experience from Southern Italy. [Abstract]: COVID-19 pandemic turned the entire health-care system organization upside-down, suspending elective activities and outpatient services. In Italy, we are entering a second phase of the pandemic and se...
33,067,522
Mod Pathol
Development of a prognostic model for mortality in COVID-19 infection using machine learning.
Coronavirus disease 2019 (COVID-19) is a novel disease resulting from infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has quickly risen since the beginning of 2020 to become a global pandemic. As a result of the rapid growth of COVID-19, hospitals are tasked with managing an increasin...
Journal Article
Booth, Adam L;Abels, Elizabeth;McCaffrey, Peter
10.1038/s41379-020-00700-x
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Development of a prognostic model for mortality in COVID-19 infection using machine learning. [Abstract]: Coronavirus disease 2019 (COVID-19) is a novel disease resulting from infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has quickly risen since the beginning of 2020 to bec...
32,835,210
Biosaf Health
Clinical characteristics of patients diagnosed with COVID-19 in Beijing.
This study aimed to determine the clinical characteristics of patients diagnosed with the coronavirus disease 2019 (COVID-19). Clinical data of COVID-19 patients diagnosed between January 28, 2020 and February 23, 2020 at the Beijing You'an Hospital were summarized and analyzed. Overall, 45 (18 men and 27 women) patien...
covid-19;clinical characteristics;diagnosis;prognosis;sars-cov-2;treatment
Case Reports
Jin, Aihua;Yan, Benyong;Hua, Wei;Feng, Dandan;Xu, Bin;Liang, Lianchun;Guo, Caiping
10.1016/j.bsheal.2020.05.003
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical characteristics of patients diagnosed with COVID-19 in Beijing. [Abstract]: This study aimed to determine the clinical characteristics of patients diagnosed with the coronavirus disease 2019 (COVID-19). Clinical data of COVID-19 patients diagnosed between January 28, 2020 and February 23, 2020 at the ...
32,329,920
Muscle Nerve
The care of patients with Duchenne, Becker, and other muscular dystrophies in the COVID-19 pandemic.
The coronavirus disease 2019 (COVID-19) pandemic has resulted in the reorganization of health-care settings affecting clinical care delivery to patients with Duchenne and Becker muscular dystrophy (DBMD) as well as other inherited muscular dystrophies. The magnitude of the impact of this public health emergency on the ...
bmd;covid-19;dmd;consensus;muscular dystrophy;recommendations
Journal Article;Review
Veerapandiyan, Aravindhan;Wagner, Kathryn R;Apkon, Susan;McDonald, Craig M;Mathews, Katherine D;Parsons, Julie A;Wong, Brenda L;Eichinger, Katy;Shieh, Perry B;Butterfield, Russell J;Rao, Vamshi K;Smith, Edward C;Proud, Crystal M;Connolly, Anne M;Ciafaloni, Emma
10.1002/mus.26902
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The care of patients with Duchenne, Becker, and other muscular dystrophies in the COVID-19 pandemic. [Abstract]: The coronavirus disease 2019 (COVID-19) pandemic has resulted in the reorganization of health-care settings affecting clinical care delivery to patients with Duchenne and Becker muscular dystrophy (...
32,950,045
Turk J Med Sci
Characteristics and Mortality Determinants of COVID-19 Patients Undergoing Haemodialysis.
BACKGROUND/AIM: COVID-19 infection which started in Wuhan City, China in December 2019 turned into a pandemic in a very short time, affecting mainly the elderly and those with serious chronic illnesses. COVID-19 infection has been observed with a high mortality rate especially in patients undergoing maintenance haemodi...
covid-19;chronic renal failure;hemodialysis
Journal Article
SIpahI, SavaS;DheIr, Hamad;ToCoGlu, Aysel;BektaS, MelIke;ACikgOz, SeyyId BIlal;GenC, Ahmed CIhad;Mutlu, Fuldem;KOroGlu, Mehmet;Erdem, AlI Fuat;Karabay, OGuz
10.3906/sag-2006-54
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Characteristics and Mortality Determinants of COVID-19 Patients Undergoing Haemodialysis. [Abstract]: BACKGROUND/AIM: COVID-19 infection which started in Wuhan City, China in December 2019 turned into a pandemic in a very short time, affecting mainly the elderly and those with serious chronic illnesses. COVID-...
33,002,677
Clin Neurol Neurosurg
The longitudinal impact of COVID-19 pandemic on neurosurgical practice.
OBJECTIVE: This observational cross-sectional multicenter study aimed to evaluate the longitudinal impact of the coronavirus disease 2019 (COVID-19) pandemic on neurosurgical practice. METHODS: We included 29 participating neurosurgeons in centers from all geographical regions in the Kingdom of Saudi Arabia. The study ...
covid-19;impact;neurosurgery;neurosurgical practice;pandemic
Journal Article;Multicenter Study;Observational Study;Research Support, Non-U.S. Gov't
Bajunaid, Khalid;Alatar, Abdullah;Alqurashi, Ashwag;Alkutbi, Mohammad;Alzahrani, Anas H;Sabbagh, Abdulrahman J;Alobaid, Abdullah;Barnawi, Abdulwahed;Alferayan, Ahmed A;Alkhani, Ahmed M;Bin Salamah, Ali;Sheikh, Bassem Y;Alotaibi, Fahad E;Alabbas, Faisal;Farrash, Faisal;Al-Jehani, Hosam M;Alhabib, Husam;Alnaami, Ibrahim;...
10.1016/j.clineuro.2020.106237
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The longitudinal impact of COVID-19 pandemic on neurosurgical practice. [Abstract]: OBJECTIVE: This observational cross-sectional multicenter study aimed to evaluate the longitudinal impact of the coronavirus disease 2019 (COVID-19) pandemic on neurosurgical practice. METHODS: We included 29 participating neur...
31,994,738
J Med Virol
The 2019-new coronavirus epidemic: Evidence for virus evolution.
There is a worldwide concern about the new coronavirus 2019-nCoV as a global public health threat. In this article, we provide a preliminary evolutionary and molecular epidemiological analysis of this new virus. A phylogenetic tree has been built using the 15 available whole genome sequences of 2019-nCoV, 12 whole geno...
sars coronavirus;coronavirus;epidemiology;macromolecular design
Journal Article;Comment
Benvenuto, Domenico;Giovanetti, Marta;Ciccozzi, Alessandra;Spoto, Silvia;Angeletti, Silvia;Ciccozzi, Massimo
10.1002/jmv.25688
[ 0, 0, 0, 1, 1, 0, 0 ]
[Title]: The 2019-new coronavirus epidemic: Evidence for virus evolution. [Abstract]: There is a worldwide concern about the new coronavirus 2019-nCoV as a global public health threat. In this article, we provide a preliminary evolutionary and molecular epidemiological analysis of this new virus. A phylogenetic tree ha...
33,051,005
J Diabetes Complications
Surgical treatment of diabetic foot ulcers during the COVID-19 pandemic in China.
Diabetic foot ulcers are among the most serious complications of diabetes. If left untreated, these ulcers can lead to severe infection and gangrene; in some instances, they may result in death. Thus, timely treatment of diabetic foot ulcers is extremely important. However, timely patient treatment during the COVID-19 ...
covid-19;diabetes;diabetic foot ulcer;sars-cov-2
Journal Article
Tao, Fenghua;Tang, Xiaoyan;Tao, Hai;Luo, Yue;Cao, Hui;Xiang, Wei;Zhao, Yingchun;Jin, Lin
10.1016/j.jdiacomp.2020.107622
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Surgical treatment of diabetic foot ulcers during the COVID-19 pandemic in China. [Abstract]: Diabetic foot ulcers are among the most serious complications of diabetes. If left untreated, these ulcers can lead to severe infection and gangrene; in some instances, they may result in death. Thus, timely treatment...
32,984,855
Cell Rep Med
Oral SARS-CoV-2 Inoculation Establishes Subclinical Respiratory Infection with Virus Shedding in Golden Syrian Hamsters.
Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) is transmitted largely by respiratory droplets or airborne aerosols. Despite being frequently found in the immediate environment and feces of patients, evidence supporting the oral acquisition of SARS-CoV-2 is unavailable. Using the Syrian hamster model, we d...
covid-19;sars-cov-2;coronavirus;feces;gastrointestinal;hamster;oral;subclinical
Journal Article
Lee, Andrew Chak-Yiu;Zhang, Anna Jinxia;Chan, Jasper Fuk-Woo;Li, Can;Fan, Zhimeng;Liu, Feifei;Chen, Yanxia;Liang, Ronghui;Sridhar, Siddharth;Cai, Jian-Piao;Poon, Vincent Kwok-Man;Chan, Chris Chung-Sing;To, Kelvin Kai-Wang;Yuan, Shuofeng;Zhou, Jie;Chu, Hin;Yuen, Kwok-Yung
10.1016/j.xcrm.2020.100121
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Oral SARS-CoV-2 Inoculation Establishes Subclinical Respiratory Infection with Virus Shedding in Golden Syrian Hamsters. [Abstract]: Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) is transmitted largely by respiratory droplets or airborne aerosols. Despite being frequently found in the immediate ...
32,682,810
Diabetes Res Clin Pract
Demographic and clinical features of critically ill patients with COVID-19 in Greece: The burden of diabetes and obesity.
AIMS: The aim of the study was to investigate the association between type-2 diabetes mellitus, other underlying diseases and obesity with the outcomes of critically ill Covid-19 patients in Greece. METHODS: In this retrospective observational multi-centre study, data and outcomes of 90 RNA 2109-nCoV confirmed critical...
covid-19;critically ill;greece;intensive care unit;obesity;type-2 diabetes
Journal Article;Multicenter Study;Observational Study
Halvatsiotis, P;Kotanidou, A;Tzannis, K;Jahaj, E;Magira, E;Theodorakopoulou, M;Konstandopoulou, G;Gkeka, E;Pourzitaki, C;Kapravelos, N;Papoti, S;Sileli, M;Gogos, C;Velissaris, D;Markou, N;Stefanatou, E;Vlachogianni, G;Aimoniotou, E;Komnos, A;Zafeiridis, T;Koulouvaris, P;Armaganidis, A;Bamias, A;Dimopoulos, G
10.1016/j.diabres.2020.108331
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Demographic and clinical features of critically ill patients with COVID-19 in Greece: The burden of diabetes and obesity. [Abstract]: AIMS: The aim of the study was to investigate the association between type-2 diabetes mellitus, other underlying diseases and obesity with the outcomes of critically ill Covid-1...
32,971,210
Food Chem Toxicol
Comprehensive assessment of side effects in COVID-19 drug pipeline from a network perspective.
Currently, coronavirus disease 2019 (COVID-19), has posed an imminent threat to global public health. Although some current therapeutic agents have showed potential prevention or treatment, a growing number of associated adverse events have occurred on patients with COVID-19 in the course of medical treatment. Therefor...
cmap;covid-19 drug;network proximity;openvigil;pharmacovigilance;side effect
Journal Article
Wu, Qihui;Fan, Xiude;Hong, Honghai;Gu, Yong;Liu, Zhihong;Fang, Shuhuan;Wang, Qi;Cai, Chuipu;Fang, Jiansong
10.1016/j.fct.2020.111767
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Comprehensive assessment of side effects in COVID-19 drug pipeline from a network perspective. [Abstract]: Currently, coronavirus disease 2019 (COVID-19), has posed an imminent threat to global public health. Although some current therapeutic agents have showed potential prevention or treatment, a growing numb...
32,238,612
Indian Pediatr
Novel Coronavirus 2019 (2019-nCoV) Infection: Part I - Preparedness and Management in the Pediatric Intensive Care Unit in Resource-limited Settings.
First reported in China, the 2019 novel coronavirus has been spreading across the globe. Till 26 March, 2020, 416,686 cases have been diagnosed and 18,589 have died the world over. The coronavirus disease mainly starts with a respiratory illness and about 5-16% require intensive care management for acute respiratory di...
Journal Article
Ravikumar, Namita;Nallasamy, Karthi;Bansal, Arun;Angurana, Suresh Kumar;Basavaraja, G V;Sundaram, Manu;Lodha, Rakesh;Gupta, Dhiren;Jayashree, Muralidharan
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Novel Coronavirus 2019 (2019-nCoV) Infection: Part I - Preparedness and Management in the Pediatric Intensive Care Unit in Resource-limited Settings. [Abstract]: First reported in China, the 2019 novel coronavirus has been spreading across the globe. Till 26 March, 2020, 416,686 cases have been diagnosed and 1...
32,581,016
Ann Clin Lab Sci
Clinical Characteristics and Blood Test Results in COVID-19 Patients.
OBJECTIVE: An outbreak of pneumonia named COVID-19 caused by a novel coronavirus in Wuhan is rapidly spreading worldwide. The objective of the present study was to clarify further the clinical characteristics and blood parameters in COVID-19 patients. MATERIALS AND METHODS: Twenty-three suspected patients and 64 patien...
covid-19;blood test;coronavirus;hospital stay;pneumonia
Journal Article;Retracted Publication
An, Xu-Sheng;Li, Xiang-Yu;Shang, Fu-Tai;Yang, Shu-Feng;Zhao, Jun-Yan;Yang, Xiao-Zhong;Wang, Hong-Gang
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical Characteristics and Blood Test Results in COVID-19 Patients. [Abstract]: OBJECTIVE: An outbreak of pneumonia named COVID-19 caused by a novel coronavirus in Wuhan is rapidly spreading worldwide. The objective of the present study was to clarify further the clinical characteristics and blood parameters...
32,380,565
Am J Perinatol
COVID-19 in Newborns and Infants-Low Risk of Severe Disease: Silver Lining or Dark Cloud?
One hundred years after the 1918 influenza pandemic, we now face another pandemic with the severe acute respiratory syndrome-novel coronavirus-2 (SARS-CoV-2). There is considerable variability in the incidence of infection and severe disease following exposure to SARS-CoV-2. Data from China and the United States sugges...
Journal Article
Rawat, Munmun;Chandrasekharan, Praveen;Hicar, Mark D;Lakshminrusimha, Satyan
10.1055/s-0040-1710512
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: COVID-19 in Newborns and Infants-Low Risk of Severe Disease: Silver Lining or Dark Cloud? [Abstract]: One hundred years after the 1918 influenza pandemic, we now face another pandemic with the severe acute respiratory syndrome-novel coronavirus-2 (SARS-CoV-2). There is considerable variability in the incidence...
32,720,256
Can J Anaesth
Efficacy and safety of decontamination for N95 respirator reuse: a systematic literature search and narrative synthesis.
PURPOSE: Under times of supply chain stress, the availability of some medical equipment and supplies may become limited. The current pandemic involving severe acute respiratory syndrome coronavirus 2 has highlighted limitations to the ordinary provision of personal protective equipment (PPE). For perioperative healthca...
covid-19;n95 cleaning;heat inactivation;hydrogen peroxide sterilization
Journal Article;Review
Steinberg, Benjamin E;Aoyama, Kazuyoshi;McVey, Mark;Levin, David;Siddiqui, Asad;Munshey, Farrukh;Goldenberg, Neil M;Faraoni, David;Maynes, Jason T
10.1007/s12630-020-01770-w
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Efficacy and safety of decontamination for N95 respirator reuse: a systematic literature search and narrative synthesis. [Abstract]: PURPOSE: Under times of supply chain stress, the availability of some medical equipment and supplies may become limited. The current pandemic involving severe acute respiratory s...
32,325,129
J Infect
The profile of peripheral blood lymphocyte subsets and serum cytokines in children with 2019 novel coronavirus pneumonia.
OBJECTIVES: The study was aimed at investigating the characteristics of peripheral blood lymphocyte subsets and serum cytokines in children with 2019 novel coronavirus (2019-nCoV) pneumonia. METHODS: Children with 2019-nCoV pneumonia or with respiratory syncytial virus (RSV) pneumonia were included. Data including lymp...
2019 novel coronavirus pneumonia;children;lymphocyte subsets;serum cytokines
Comparative Study;Journal Article
Li, Hui;Chen, Kailan;Liu, Maochang;Xu, Hua;Xu, Qiong
10.1016/j.jinf.2020.04.001
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: The profile of peripheral blood lymphocyte subsets and serum cytokines in children with 2019 novel coronavirus pneumonia. [Abstract]: OBJECTIVES: The study was aimed at investigating the characteristics of peripheral blood lymphocyte subsets and serum cytokines in children with 2019 novel coronavirus (2019-nCo...
32,530,507
J Med Virol
Can steroids reverse the severe COVID-19 induced "cytokine storm"?
Severe coronavirus disease (COVID-19) is characterized by an excessive proinflammatory cytokine storm, resulting in acute lung injury and development of acute respiratory distress syndrome (ARDS). The role of corticosteroids is controversial in severe COVID-19 pneumonia and associated hyper-inflammatory syndrome. We re...
ards;covid-19;corticosteroids;cytokine storm;hyper-inflammatory syndrome
Journal Article;Observational Study
Kolilekas, Lykourgos;Loverdos, Konstantinos;Giannakaki, Styliani;Vlassi, Lamprini;Levounets, Anastasia;Zervas, Eleftherios;Gaga, Mina
10.1002/jmv.26165
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Can steroids reverse the severe COVID-19 induced "cytokine storm"? [Abstract]: Severe coronavirus disease (COVID-19) is characterized by an excessive proinflammatory cytokine storm, resulting in acute lung injury and development of acute respiratory distress syndrome (ARDS). The role of corticosteroids is cont...
32,301,298
J Korean Med Sci
A Brief Telephone Severity Scoring System and Therapeutic Living Centers Solved Acute Hospital-Bed Shortage during the COVID-19 Outbreak in Daegu, Korea.
With the epidemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2, the number of infected patients was rapidly increasing in Daegu, Korea. With a maximum of 741 new patients per day in the city as of February 29, 2020, hospital-bed shortage was a great challenge to the l...
brief severity scoring system;covid-19;facility isolation;telephone;therapeutic living center
Journal Article
Kim, Shin Woo;Lee, Kyeong Soo;Kim, Keonyeop;Lee, Jung Jeung;Kim, Jong Yeon
10.3346/jkms.2020.35.e152
[ 1, 1, 1, 0, 0, 0, 0 ]
[Title]: A Brief Telephone Severity Scoring System and Therapeutic Living Centers Solved Acute Hospital-Bed Shortage during the COVID-19 Outbreak in Daegu, Korea. [Abstract]: With the epidemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2, the number of infected patien...
32,719,619
Front Physiol
While We Wait for a Vaccine Against SARS-CoV-2, Why Not Think About Available Drugs?
At the time of reception of this article (April 2, 2020), efforts to develop a specific vaccine against SARS-Cov-2, the causative agent of the coronavirus disease 2019 (COVID-19), had just begun trial phase 1, but full validation of this and other current developments is likely to take many more months to reach complet...
ace2;covid-19;sars-cov-2;coronavirus;design drugs;prophylaxis
Journal Article;Review
Barrantes, Francisco J
10.3389/fphys.2020.00820
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: While We Wait for a Vaccine Against SARS-CoV-2, Why Not Think About Available Drugs? [Abstract]: At the time of reception of this article (April 2, 2020), efforts to develop a specific vaccine against SARS-Cov-2, the causative agent of the coronavirus disease 2019 (COVID-19), had just begun trial phase 1, but ...
32,603,060
Acta Gastroenterol Belg
Liver transplantation during the COVID-19 epidemic : recommendations from the Belgian Liver Intestine Transplant Committee (BeLIAC).
Since January 2020, the Novel Coronavirus Disease 2019 (COVID-19) pandemic has dramatically impacted the world. In March 2020, the COVID-19 epidemic reached Belgium creating uncertainty towards all aspects of life. There has been an impressive capacity and solidarity of all healthcare professionals to acutely reconvert...
covid-19 epidemic;liver transplantation;resources
Journal Article
Dahlqvist, G;Ciccarelli, O;Van Vlierberghe, H;Berrevoet, F;Vanwolleghem, T;Ysebaert, D;Gustot, T;Lucidi, V;Delwaide, J;Detry, O;Delbouille, M H;Sokal, E;Nevens, F;Pirenne, J
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Liver transplantation during the COVID-19 epidemic : recommendations from the Belgian Liver Intestine Transplant Committee (BeLIAC). [Abstract]: Since January 2020, the Novel Coronavirus Disease 2019 (COVID-19) pandemic has dramatically impacted the world. In March 2020, the COVID-19 epidemic reached Belgium c...
32,617,864
Daru
Short and long term impacts of COVID-19 on the pharmaceutical sector.
BACKGROUND: The novel coronavirus disease 2019 (COVID-19) was characterized as a global pandemic by the WHO on March 11th, 2020. This pandemic had major effects on the health market, the pharmaceutical sector, and was associated with considerable impacts; which may appear in short and long-term time-horizon and need id...
covid-19;corona virus;health market;pharmaceutical industry;pharmaceutical market;sars-cov-2;tele-health
Journal Article
Ayati, Nayyereh;Saiyarsarai, Parisa;Nikfar, Shekoufeh
10.1007/s40199-020-00358-5
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Short and long term impacts of COVID-19 on the pharmaceutical sector. [Abstract]: BACKGROUND: The novel coronavirus disease 2019 (COVID-19) was characterized as a global pandemic by the WHO on March 11th, 2020. This pandemic had major effects on the health market, the pharmaceutical sector, and was associated ...
32,395,702
FASEB Bioadv
The role of growth factor receptors in viral infections: An opportunity for drug repurposing against emerging viral diseases such as COVID-19?
Growth factor receptors are known to be involved in the process of viral infection. Many viruses not only use growth factor receptors to physically attach to the cell surface and internalize, but also divert receptor tyrosine kinase signaling in order to replicate. Thus, repurposing drugs that have initially been devel...
covid-19;sars-cov-2;cancer drugs;growth factors;heparan sulfate;heparin;inhibitors;tyrosine kinase;virus
Journal Article
Hondermarck, Hubert;Bartlett, Nathan W;Nurcombe, Victor
10.1096/fba.2020-00015
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: The role of growth factor receptors in viral infections: An opportunity for drug repurposing against emerging viral diseases such as COVID-19? [Abstract]: Growth factor receptors are known to be involved in the process of viral infection. Many viruses not only use growth factor receptors to physically attach t...
32,476,233
Am J Transplant
Strategies for liver transplantation during the SARS-CoV-2 outbreak: Preliminary experience from a single center in France.
Liver transplantation (LT) during the ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is challenging given the urgent need to reallocate resources to other areas of patient care. Available guidelines recommend reorganizing transplant care, but data on clinical experience in the context of ...
cancer/malignancy/neoplasia;clinical decision-making;clinical research/practice;diagnostic techniques and imaging;infection and infectious agents - viral;liver transplantation/hepatology;organ procurement and allocation;risk assessment/risk stratification
Journal Article
Muller, Xavier;Tilmans, Gilles;Chenevas-Paule, Quentin;Lebosse, Fanny;Antonini, Teresa;Poinsot, Domitille;Rode, Agnes;Guichon, Celine;Schmitt, Zoe;Ducerf, Christian;Mohkam, Kayvan;Lesurtel, Mickael;Mabrut, Jean-Yves
10.1111/ajt.16082
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Strategies for liver transplantation during the SARS-CoV-2 outbreak: Preliminary experience from a single center in France. [Abstract]: Liver transplantation (LT) during the ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is challenging given the urgent need to reallocate resource...
32,592,842
Diabetes Res Clin Pract
Diabetes and COVID-19: IDF perspective in the Western Pacific region.
The World Health Organization (WHO) declared a pandemic, the highest risk level in the infectious disease alert phase, on 11 March 2020. In the Western Pacific Region (WPR), 192,016 confirmed cases with 7125 deaths had been reported as of 8 June 2020. In people with diabetes COVID-19 can be more difficult to treat due ...
covid-19;diabetes
Journal Article
Hwang, Yerin;Khasag, Altaisaikhan;Jia, Weiping;Jenkins, Alicia;Huang, Chien-Ning;Yabe, Daisuke;Kim, Doo-Man;Kadowaki, Takashi;Lee, Moon-Kyu
10.1016/j.diabres.2020.108278
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Diabetes and COVID-19: IDF perspective in the Western Pacific region. [Abstract]: The World Health Organization (WHO) declared a pandemic, the highest risk level in the infectious disease alert phase, on 11 March 2020. In the Western Pacific Region (WPR), 192,016 confirmed cases with 7125 deaths had been repor...
32,813,168
Eur Arch Otorhinolaryngol
Face to face with COVID-19: highlights of challenges encountered in various ENT practices across the Czech Republic (a national survey).
The SARS-CoV-2 virus causing the COVID-19 disease created considerable complications and disruptions due to it's pandemic spread. The nature of the disease left certain clinical specialties more vulnerable than others, causing serious problems with organization of care of patients. Most studies concentrated on protocol...
covid-19;disposable aids;ent;financial loss;ppe;pandemic
Journal Article
Guha, Anasuya;Plzak, Jan;Chovanec, Martin
10.1007/s00405-020-06280-5
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Face to face with COVID-19: highlights of challenges encountered in various ENT practices across the Czech Republic (a national survey). [Abstract]: The SARS-CoV-2 virus causing the COVID-19 disease created considerable complications and disruptions due to it's pandemic spread. The nature of the disease left c...
32,341,143
J Clin Microbiol
Comparison of Four Molecular In Vitro Diagnostic Assays for the Detection of SARS-CoV-2 in Nasopharyngeal Specimens.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the novel human coronavirus that causes coronavirus disease 2019 (COVID-19), was first discovered in December 2019 as the cause of an outbreak of pneumonia in the city of Wuhan, Hubei province, China. The clinical presentation of COVID-19 is fairly nonspecif...
covid-19;eua;sars-cov-2;molecular diagnostics;nasopharyngeal;real-time rt-pcr
Comparative Study;Evaluation Study;Journal Article
Zhen, Wei;Manji, Ryhana;Smith, Elizabeth;Berry, Gregory J
10.1128/JCM.00743-20
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Comparison of Four Molecular In Vitro Diagnostic Assays for the Detection of SARS-CoV-2 in Nasopharyngeal Specimens. [Abstract]: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the novel human coronavirus that causes coronavirus disease 2019 (COVID-19), was first discovered in December 2019 as th...
32,921,716
Acta Biomed
The role of imaging and other diagnostic approaches in COVID-19.
As the COVID 19 pandemic develops across the globe, a large amount of literature has been written about the different ways in which we can diagnose and investigate someone suspected of being infected with the new coronavirus. Many approaches highlight the importance of using reverse transcriptase polymerase chain react...
Journal Article;Review
Shammus, Rohma;Mahbub, Samiha;Rauf, Muhammad Atif;Harky, Amer
10.23750/abm.v91i3.9822
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: The role of imaging and other diagnostic approaches in COVID-19. [Abstract]: As the COVID 19 pandemic develops across the globe, a large amount of literature has been written about the different ways in which we can diagnose and investigate someone suspected of being infected with the new coronavirus. Many app...
32,253,535
Eur Arch Otorhinolaryngol
Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease (COVID-19): a multicenter European study.
OBJECTIVE: To investigate the occurrence of olfactory and gustatory dysfunctions in patients with laboratory-confirmed COVID-19 infection. METHODS: Patients with laboratory-confirmed COVID-19 infection were recruited from 12 European hospitals. The following epidemiological and clinical outcomes have been studied: age,...
anosmia;covid;covid-19;coronavirus;dysgeusia;ent;gustatory;hyposmia;infection;loss;olfaction;olfactory;sars-cov-2;smell;taste
Journal Article;Multicenter Study
Lechien, Jerome R;Chiesa-Estomba, Carlos M;De Siati, Daniele R;Horoi, Mihaela;Le Bon, Serge D;Rodriguez, Alexandra;Dequanter, Didier;Blecic, Serge;El Afia, Fahd;Distinguin, Lea;Chekkoury-Idrissi, Younes;Hans, Stephane;Delgado, Irene Lopez;Calvo-Henriquez, Christian;Lavigne, Philippe;Falanga, Chiara;Barillari, Maria Ros...
10.1007/s00405-020-05965-1
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease (COVID-19): a multicenter European study. [Abstract]: OBJECTIVE: To investigate the occurrence of olfactory and gustatory dysfunctions in patients with laboratory-confirmed COVID-19 infection. M...
32,950,636
Microb Pathog
Use of Nasoil(R) via intranasal to control the harmful effects of Covid-19.
In the absence of vaccines and antiviral drugs available to prevent and treat COVID-19, it becomes imperative to find or use all those products with the potential to fight this virus. This article is an attempt to propose ways to prevent, treat and control the COVID-19 virus, using a product based on plant extracts wit...
asclepias curassavica;coronavirus;covid-19;nasoil(r);plant extracts;sars-cov-2
Journal Article
Cuevas-Barragan, Carlos Eduardo;Buenrostro-Nava, Marco Tulio;Palos-Gomez, Gabriela Monserrat;Ramirez-Padilla, Elisa Alejandra;Mendoza-Macias, Blanca Isabel;Rivas-Caceres, Raymundo Rene
10.1016/j.micpath.2020.104504
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Use of Nasoil(R) via intranasal to control the harmful effects of Covid-19. [Abstract]: In the absence of vaccines and antiviral drugs available to prevent and treat COVID-19, it becomes imperative to find or use all those products with the potential to fight this virus. This article is an attempt to propose w...
32,468,508
Intern Emerg Med
Plasma from donors recovered from the new Coronavirus 2019 as therapy for critical patients with COVID-19 (COVID-19 plasma study): a multicentre study protocol.
Since the end of 2019, a new coronavirus strain has been reported in the Chinese province of Wuhan, indicated as 2019-nCoV or SARS-CoV-2. In February 2020, the first case of transmission on Italian soil was reported. On March 09, 2020, at the time of protocol design, the Italian Ministry of Health reported 10,149 peopl...
covid-19;hyperimmune plasma;plasmapheresis
Clinical Trial Protocol;Journal Article;Multicenter Study
Perotti, Cesare;Del Fante, Claudia;Baldanti, Fausto;Franchini, Massimo;Percivalle, Elena;Vecchio Nepita, Edoardo;Seminari, Elena;De Silvestri, Annalisa;Bruno, Raffele;Klersy, Catherine
10.1007/s11739-020-02384-2
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Plasma from donors recovered from the new Coronavirus 2019 as therapy for critical patients with COVID-19 (COVID-19 plasma study): a multicentre study protocol. [Abstract]: Since the end of 2019, a new coronavirus strain has been reported in the Chinese province of Wuhan, indicated as 2019-nCoV or SARS-CoV-2. ...
32,494,576
ERJ Open Res
COVID-19 follow-up planning: what will we be missing?
There is a real need for a discharge plan for COVID-19 survivors in the UK. Follow-up imaging could help assess the resolution of infection, exclude underlying malignancy and identify post-inflammatory fibrosis. https://bit.ly/2YJ8hyg.
Journal Article
Lee, Lydia;Iyer, Sriram;Jose, Ricardo J;Manuel, Ari
10.1183/23120541.00198-2020
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: COVID-19 follow-up planning: what will we be missing? [Abstract]: There is a real need for a discharge plan for COVID-19 survivors in the UK. Follow-up imaging could help assess the resolution of infection, exclude underlying malignancy and identify post-inflammatory fibrosis. https://bit.ly/2YJ8hyg. [Keywords...
32,697,705
J Affect Disord
Electroconvulsive therapy protocol adaptation during the COVID-19 pandemic.
BACKGROUND: During the COVID-19 pandemic, electroconvulsive therapy units have had to confront challenges such as the infectious hazard due to aerosol-generating ventilation, or the lack of staff and material resources. Our objective was to elaborate a protocol to make ECT during the COVID-19 pandemic a safer procedure...
covid-19;coronavirus;ect;electroconvulsive therapy;protocol;sars-cov-2
Journal Article
Gil-Badenes, Joaquin;Valero, Ricard;Valenti, Marc;Macau, Elisabet;Bertran, Maria Jesus;Claver, Gerard;Bioque, Miquel;Baeza, Inmaculada;Bastidas Salvado, Anna;Lombrana Mencia, Maria;Pacchiarotti, Isabella;Bernardo, Miquel;Vieta, Eduard
10.1016/j.jad.2020.06.051
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Electroconvulsive therapy protocol adaptation during the COVID-19 pandemic. [Abstract]: BACKGROUND: During the COVID-19 pandemic, electroconvulsive therapy units have had to confront challenges such as the infectious hazard due to aerosol-generating ventilation, or the lack of staff and material resources. Our...
32,217,900
J Comput Assist Tomogr
High-Resolution Computed Tomography Manifestations of 5 Pediatric Patients With 2019 Novel Coronavirus.
We present clinical and chest computed tomography (CT) features of 5 cases of pediatric patients with 2019 novel coronavirus. Two patients had fever and dry cough, whereas the rest of 3 patients were asymptomatic. Three patients had unilateral ground glass opacities with or without consolidation in the subpleural regio...
Case Reports;Journal Article
Liu, Mengqi;Song, Zongbiao;Xiao, Kaihu
10.1097/RCT.0000000000001023
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: High-Resolution Computed Tomography Manifestations of 5 Pediatric Patients With 2019 Novel Coronavirus. [Abstract]: We present clinical and chest computed tomography (CT) features of 5 cases of pediatric patients with 2019 novel coronavirus. Two patients had fever and dry cough, whereas the rest of 3 patients ...
32,584,780
J Med Internet Res
Approaches Based on Artificial Intelligence and the Internet of Intelligent Things to Prevent the Spread of COVID-19: Scoping Review.
BACKGROUND: Artificial intelligence (AI) and the Internet of Intelligent Things (IIoT) are promising technologies to prevent the concerningly rapid spread of coronavirus disease (COVID-19) and to maximize safety during the pandemic. With the exponential increase in the number of COVID-19 patients, it is highly possible...
covid-19;sars-cov-2;artificial intelligence;internet of things;machine learning;modeling;novel coronavirus;robotics;simulation;telemedicine
Journal Article;Review
Adly, Aya Sedky;Adly, Afnan Sedky;Adly, Mahmoud Sedky
10.2196/19104
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Approaches Based on Artificial Intelligence and the Internet of Intelligent Things to Prevent the Spread of COVID-19: Scoping Review. [Abstract]: BACKGROUND: Artificial intelligence (AI) and the Internet of Intelligent Things (IIoT) are promising technologies to prevent the concerningly rapid spread of coronav...
32,662,814
Brief Bioinform
Integrative pharmacological mechanism of vitamin C combined with glycyrrhizic acid against COVID-19: findings of bioinformatics analyses.
OBJECTIVE: Coronavirus disease 2019 (COVID-19) is a fatal and fast-spreading viral infection. To date, the number of COVID-19 patients worldwide has crossed over six million with over three hundred and seventy thousand deaths (according to the data from World Health Organization; updated on 2 June 2020). Although COVID...
covid-19;bioinformatics analysis;biotarget;glycyrrhizic acid;vitamin c
Journal Article;Research Support, Non-U.S. Gov't
Li, Rong;Wu, Ka;Li, Yu;Liang, Xiao;Lai, Keng Po;Chen, Jian
10.1093/bib/bbaa141
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Integrative pharmacological mechanism of vitamin C combined with glycyrrhizic acid against COVID-19: findings of bioinformatics analyses. [Abstract]: OBJECTIVE: Coronavirus disease 2019 (COVID-19) is a fatal and fast-spreading viral infection. To date, the number of COVID-19 patients worldwide has crossed over...
33,078,010
Recenti Prog Med
[Retrospective study on a CoViD-19 outbreak that developed in February during a dinner in the municipality of Capannori (Lucca).]
The first cases of SARS-CoV-2 were reported in Wuhan, China, in December 2019. In January the disease spread rapidly to other regions and beyond Chinese borders until it reached Italy where, on February 21, the first case of non-imported contagion was found. On the same date, as the commercial activities were still reg...
Journal Article
Orsucci, Giulia;Rocchi, Rachele;Menconi, Arianna;Salvoni, Franco Antonio
10.1701/3453.34420
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [Retrospective study on a CoViD-19 outbreak that developed in February during a dinner in the municipality of Capannori (Lucca).] [Abstract]: The first cases of SARS-CoV-2 were reported in Wuhan, China, in December 2019. In January the disease spread rapidly to other regions and beyond Chinese borders until it...
32,528,819
Osong Public Health Res Perspect
Coronavirus Disease-19: Quarantine Framework for Travelers Entering Korea.
South Korea is operating a flexible quarantine management system which is based on the results of epidemiological investigations of patients arriving from overseas with coronavirus disease-19 (COVID-19), and closely monitoring COVID-19 outbreaks. South Korea has designated countries with a localized, high prevalence of...
covid-19;immigrant;quarantine
Journal Article
10.24171/j.phrp.2020.11.3.04
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Coronavirus Disease-19: Quarantine Framework for Travelers Entering Korea. [Abstract]: South Korea is operating a flexible quarantine management system which is based on the results of epidemiological investigations of patients arriving from overseas with coronavirus disease-19 (COVID-19), and closely monitori...
33,049,464
J Stroke Cerebrovasc Dis
The impact of COVID-19 on acute ischemic stroke admissions: Analysis from a community-based tertiary care center.
BACKGROUND/OBJECTIVE: To evaluate the impact of the COVID-19 pandemic on hospital admissions and outcomes in patients admitted with acute ischemic stroke. METHODS: Single-center retrospective analysis of patients admitted to the hospital with acute ischemic stroke, between December 1(st), 2019 and June 30(th), 2020. Ou...
acute ischemic stroke;covid-19;hospital admission;iv thrombolysis;mechanical thrombectomy;mortality;pandemic
Comparative Study;Journal Article
Wang, Jing;Chaudhry, Saqib A;Tahsili-Fahadan, Pouya;Altaweel, Laith R;Bashir, Sairah;Bahiru, Zelalem;Fang, Yun;Qureshi, Adnan I
10.1016/j.jstrokecerebrovasdis.2020.105344
[ 1, 1, 1, 0, 0, 0, 0 ]
[Title]: The impact of COVID-19 on acute ischemic stroke admissions: Analysis from a community-based tertiary care center. [Abstract]: BACKGROUND/OBJECTIVE: To evaluate the impact of the COVID-19 pandemic on hospital admissions and outcomes in patients admitted with acute ischemic stroke. METHODS: Single-center retrosp...
32,344,449
Clin Pharmacol Ther
Finding the Dose for Hydroxychloroquine Prophylaxis for COVID-19: The Desperate Search for Effectiveness.
Hydroxychloroquine is an antimalarial drug being tested as a potential treatment for the novel coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2. Although the efficacy of hydroxychloroquine for COVID-19 remains uncertain, it may serve as a potential prophylactic ...
Journal Article;Research Support, N.I.H., Extramural
Al-Kofahi, Mahmoud;Jacobson, Pamala;Boulware, David R;Matas, Arthur;Kandaswamy, Raja;Jaber, Mutaz M;Rajasingham, Radha;Young, Jo-Anne H;Nicol, Melanie R
10.1002/cpt.1874
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Finding the Dose for Hydroxychloroquine Prophylaxis for COVID-19: The Desperate Search for Effectiveness. [Abstract]: Hydroxychloroquine is an antimalarial drug being tested as a potential treatment for the novel coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coron...
32,809,910
Acta Odontol Scand
Strategic implementation of dental infection control in resource-poor jurisdictions during COVID-19 pandemic: a perspective from South Africa.
BACKGROUND: The coronavirus disease-19 (COVID-19) pandemic caused by the severe acute respiratory syndrome Coronavirus -2 is unceasing, and the consensus is that the dental profession has to co-exist with this vicious foe for the foreseeable future. Dental professionals in resource poor countries, as opposed to those i...
africa;covid-19;sars-cov-2;dentistry;infection control
Journal Article
Blignaut, Elaine;Nemutandani, Simon;Samaranayake, Lakshman
10.1080/00016357.2020.1804073
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Strategic implementation of dental infection control in resource-poor jurisdictions during COVID-19 pandemic: a perspective from South Africa. [Abstract]: BACKGROUND: The coronavirus disease-19 (COVID-19) pandemic caused by the severe acute respiratory syndrome Coronavirus -2 is unceasing, and the consensus is...
32,420,637
Drug Dev Res
Repurposing current therapeutics for treating COVID-19: A vital role of prescription records data mining.
Since its outbreak in late 2019, the SARS-Cov-2 pandemic already infected over 3.7 million people and claimed more than 250,000 lives globally. At least 1 year may take for an approved vaccine to be in place, and meanwhile millions more could be infected, some with fatal outcome. Over thousand clinical trials with COVI...
covid-19;tmprss2;drug repositioning;drug repurposing;electronic health records (ehr)
Journal Article
Gurwitz, David
10.1002/ddr.21689
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Repurposing current therapeutics for treating COVID-19: A vital role of prescription records data mining. [Abstract]: Since its outbreak in late 2019, the SARS-Cov-2 pandemic already infected over 3.7 million people and claimed more than 250,000 lives globally. At least 1 year may take for an approved vaccine ...
32,889,885
Ann Surg
Percutaneous and Open Tracheostomy in Patients with COVID-19: Comparison and Outcomes of an Institutional Series in New York City.
OBJECTIVE: The aim of this study was to report the safety, efficacy, and early results of tracheostomy in patients with COVID-19 and determine whether differences exist between percutaneous and open methods. SUMMARY BACKGROUND DATA: Prolonged respiratory failure is common in symptomatic patients with COVID-19, the dise...
Comparative Study;Journal Article
Long, Sallie M;Chern, Alexander;Feit, Noah Z;Chung, Sei;Ramaswamy, Apoorva T;Li, Carol;Cooley, Victoria;Hill, Shanna;Rajwani, Kapil;Villena-Vargas, Jonathan;Scheneck, Edward;Stiles, Brendon;Tassler, Andrew B
10.1097/SLA.0000000000004428
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Percutaneous and Open Tracheostomy in Patients with COVID-19: Comparison and Outcomes of an Institutional Series in New York City. [Abstract]: OBJECTIVE: The aim of this study was to report the safety, efficacy, and early results of tracheostomy in patients with COVID-19 and determine whether differences exist...
32,843,823
Chaos Solitons Fractals
Spatio-temporal estimation of the daily cases of COVID-19 in worldwide using random forest machine learning algorithm.
Novel Coronavirus pandemic, which negatively affected public health in social, psychological and economical terms, spread to the whole world in a short period of 6 months. However, the rate of increase in cases was not equal for every country. The measures implemented by the countries changed the daily spreading speed ...
covid-19;estimating;machine learning;mapping;random forest
Journal Article
YeSIlkanat, Cafer Mert
10.1016/j.chaos.2020.110210
[ 0, 0, 0, 0, 0, 1, 0 ]
[Title]: Spatio-temporal estimation of the daily cases of COVID-19 in worldwide using random forest machine learning algorithm. [Abstract]: Novel Coronavirus pandemic, which negatively affected public health in social, psychological and economical terms, spread to the whole world in a short period of 6 months. However,...
32,594,909
BMC Med
Forecasting spatial, socioeconomic and demographic variation in COVID-19 health care demand in England and Wales.
BACKGROUND: COVID-19 poses one of the most profound public health crises for a hundred years. As of mid-May 2020, across the world, almost 300,000 deaths and over 4 million confirmed cases were registered. Reaching over 30,000 deaths by early May, the UK had the highest number of recorded deaths in Europe, second in th...
age;covid-19;deprivation;england;ethnicity;hospital capacity;local;nhs;population density;regional;wales
Journal Article;Research Support, Non-U.S. Gov't
Verhagen, Mark D;Brazel, David M;Dowd, Jennifer Beam;Kashnitsky, Ilya;Mills, Melinda C
10.1186/s12916-020-01646-2
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Forecasting spatial, socioeconomic and demographic variation in COVID-19 health care demand in England and Wales. [Abstract]: BACKGROUND: COVID-19 poses one of the most profound public health crises for a hundred years. As of mid-May 2020, across the world, almost 300,000 deaths and over 4 million confirmed ca...
33,067,641
Immunogenetics
Elevated interleukin-6 and adverse outcomes in COVID-19 patients: a meta-analysis based on adjusted effect estimates.
This study aimed to evaluate the association of interleukin-6 (IL-6) level with the poor outcomes in coronavirus disease 2019 (COVID-19) patients by utilizing a meta-analysis based on adjusted effect estimates. We searched the keywords from PubMed, Web of Science, and EMBASE on August 14, 2020. The pooled effects and 9...
adjusted effect estimates;adverse outcomes;covid-19;il-6;meta-analysis
Journal Article;Meta-Analysis;Research Support, Non-U.S. Gov't
Zhang, Peihua;Shi, Li;Xu, Jie;Wang, Yadong;Yang, Haiyan
10.1007/s00251-020-01179-1
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Elevated interleukin-6 and adverse outcomes in COVID-19 patients: a meta-analysis based on adjusted effect estimates. [Abstract]: This study aimed to evaluate the association of interleukin-6 (IL-6) level with the poor outcomes in coronavirus disease 2019 (COVID-19) patients by utilizing a meta-analysis based ...
32,360,516
Clin Immunol
The first case of COVID-19 treated with the complement C3 inhibitor AMY-101.
Acute respiratory distress syndrome (ARDS) is a devastating clinical manifestation of COVID-19 pneumonia and is mainly based on an immune-driven pathology. Mounting evidence suggests that COVID-19 is fueled by a maladaptive host inflammatory response that involves excessive activation of innate immune pathways. While a...
Case Reports;Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Mastaglio, Sara;Ruggeri, Annalisa;Risitano, Antonio M;Angelillo, Piera;Yancopoulou, Despina;Mastellos, Dimitrios C;Huber-Lang, Markus;Piemontese, Simona;Assanelli, Andrea;Garlanda, Cecilia;Lambris, John D;Ciceri, Fabio
10.1016/j.clim.2020.108450
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: The first case of COVID-19 treated with the complement C3 inhibitor AMY-101. [Abstract]: Acute respiratory distress syndrome (ARDS) is a devastating clinical manifestation of COVID-19 pneumonia and is mainly based on an immune-driven pathology. Mounting evidence suggests that COVID-19 is fueled by a maladaptiv...
32,376,169
J Arthroplasty
The Response of an Orthopedic Department and Specialty Hospital at the Epicenter of a Pandemic: The NYU Langone Health Experience.
As the world grapples with the COVID-19 pandemic, we as health care professionals thrive to continue to help our patients, and as orthopedic surgeons, this goal is ever more challenging. As part of a major academic tertiary medical center in New York City, the orthopedic department at New York University (NYU) Langone ...
covid -19;new york city;orthopaedics;residency;surgery;total joint arthroplasty
Journal Article
Schwarzkopf, Ran;Maher, Nolan A;Slover, James D;Strauss, Eric J;Bosco, Joseph A;Zuckerman, Joseph D
10.1016/j.arth.2020.04.041
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The Response of an Orthopedic Department and Specialty Hospital at the Epicenter of a Pandemic: The NYU Langone Health Experience. [Abstract]: As the world grapples with the COVID-19 pandemic, we as health care professionals thrive to continue to help our patients, and as orthopedic surgeons, this goal is ever...
32,983,180
Front Immunol
Neutrophil-to-Lymphocyte Ratios Are Closely Associated With the Severity and Course of Non-mild COVID-19.
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is spreading worldwide. Measuring the prevention and control of the disease has become a matter requiring urgent focus. Objective: Based on coronavirus disease 2019 (COVID-19) clinical data from Wuhan, we conducted an in-depth analysis t...
neutrophil-to-lymphocyte ratios;cytokines;immune damage;inflammation;severity and course of non-mild covid-19
Journal Article;Research Support, Non-U.S. Gov't
Qun, Sen;Wang, Yulan;Chen, Jun;Huang, Xiang;Guo, Hui;Lu, Zhaohui;Wang, Jinquan;Zheng, Changcheng;Ma, Yan;Zhu, Yuyou;Xia, Daqing;Wang, Yinzhong;He, Hongliang;Wang, Yong;Fei, Mingming;Yin, Yihong;Zheng, Mao;Xu, Yehong;Ge, Wei;Hu, Fuyong;Zhou, Jian
10.3389/fimmu.2020.02160
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Neutrophil-to-Lymphocyte Ratios Are Closely Associated With the Severity and Course of Non-mild COVID-19. [Abstract]: Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is spreading worldwide. Measuring the prevention and control of the disease has become a matter requiring urge...
32,754,962
Clin Exp Dermatol
Reduction in skin cancer diagnoses in the UK during the COVID-19 pandemic.
The UK healthcare system, including skin cancer departments, has been profoundly affected by the COVID-19 pandemic. Despite service capacity and a worldwide increase in incidence, anecdotal reports suggest a decline in skin cancer diagnoses following COVID-19. To determine if there has been a decrease in skin cancer di...
Comparative Study;Journal Article
Andrew, T W;Alrawi, M;Lovat, P
10.1111/ced.14411
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Reduction in skin cancer diagnoses in the UK during the COVID-19 pandemic. [Abstract]: The UK healthcare system, including skin cancer departments, has been profoundly affected by the COVID-19 pandemic. Despite service capacity and a worldwide increase in incidence, anecdotal reports suggest a decline in skin ...
32,581,816
Front Pharmacol
Neutrophilia and NETopathy as Key Pathologic Drivers of Progressive Lung Impairment in Patients With COVID-19.
There is an urgent need for new therapeutic strategies to contain the spread of the novel coronavirus disease 2019 (COVID-19) and to curtail its most severe complications. Severely ill patients experience pathologic manifestations of acute respiratory distress syndrome (ARDS), and clinical reports demonstrate striking ...
covid-19;sars-cov-2;acute respiratory distress syndrome;neutrophil extracellular traps;neutrophilia;neutrophils;pathogenesis;therapeutics
Journal Article
Narasaraju, Teluguakula;Tang, Benjamin M;Herrmann, Martin;Muller, Sylviane;Chow, Vincent T K;Radic, Marko
10.3389/fphar.2020.00870
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Neutrophilia and NETopathy as Key Pathologic Drivers of Progressive Lung Impairment in Patients With COVID-19. [Abstract]: There is an urgent need for new therapeutic strategies to contain the spread of the novel coronavirus disease 2019 (COVID-19) and to curtail its most severe complications. Severely ill pat...
33,062,362
Case Rep Pediatr
Discovering Associations: Kawasaki Disease and COVID-19.
The COVID-19 pandemic has resulted in over 3.6 million confirmed cases and over 254,000 deaths worldwide. It has been theorized that children who are asymptomatic or who do not display significant respiratory symptoms are potential vectors for community transmission of the SARS-CoV-2 virus. This is incompletely underst...
Case Reports
Peterson, Nicholas;Sagdeo, Kaustubh;Tyungu, Donna;Harper, Cristin;Mihaylo, Kyle;Pollak-Christian, Elza
10.1155/2020/8880242
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Discovering Associations: Kawasaki Disease and COVID-19. [Abstract]: The COVID-19 pandemic has resulted in over 3.6 million confirmed cases and over 254,000 deaths worldwide. It has been theorized that children who are asymptomatic or who do not display significant respiratory symptoms are potential vectors fo...
32,651,993
Aging (Albany NY)
Risk factors influencing the prognosis of elderly patients infected with COVID-19: a clinical retrospective study in Wuhan, China.
The mortality rate of elderly patients with Coronavirus Disease 2019 (COVID-19) was significantly higher than the overall mortality rate. However, besides age, leading death risk factors for the high mortality in elderly patients remain unidentified. This retrospective study included 210 elderly COVID-19 patients (aged...
c-reactive protein;covid-19;comorbidities;elderly patients;risk factors
Journal Article;Research Support, Non-U.S. Gov't
Gao, Shan;Jiang, Fang;Jin, Wei;Shi, Yuan;Yang, Leilei;Xia, Yanqiong;Jia, Linyan;Wang, Bo;Lin, Han;Cai, Yin;Xia, Zhengyuan;Peng, Jian
10.18632/aging.103631
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Risk factors influencing the prognosis of elderly patients infected with COVID-19: a clinical retrospective study in Wuhan, China. [Abstract]: The mortality rate of elderly patients with Coronavirus Disease 2019 (COVID-19) was significantly higher than the overall mortality rate. However, besides age, leading ...
32,507,608
Eur J Intern Med
Hepatic consequences of COVID-19 infection. Lapping or biting?
The outbreak of coronavirus disease 2019 (COVID-19) starting last December in China placed emphasis on liver involvement during infection. This review discusses the underlying mechanisms linking COVID-19 to liver dysfunction, according to recent available information, while waiting further studies. The manifestations o...
covid-19;ischemia-reperfusion damage;liver damage;nonalcoholic fatty liver disease;sars-cov-2;toll-like receptors
Journal Article;Review
Portincasa, Piero;Krawczyk, Marcin;Machill, Antonia;Lammert, Frank;Di Ciaula, Agostino
10.1016/j.ejim.2020.05.035
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: Hepatic consequences of COVID-19 infection. Lapping or biting? [Abstract]: The outbreak of coronavirus disease 2019 (COVID-19) starting last December in China placed emphasis on liver involvement during infection. This review discusses the underlying mechanisms linking COVID-19 to liver dysfunction, according ...
32,910,323
Emerg Radiol
Feasibility of using point-of-care lung ultrasound for early triage of COVID-19 patients in the emergency room.
PURPOSE: Diagnostic value of point-of-care lung ultrasound (POCUS) in detection of coronavirus disease (COVID-19) in an emergency setting is currently unclear. In this study, we aimed to compare diagnostic performance, in terms of sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV...
covid-19;emergency room;negative predictive value;pocus lung;sensitivity
Comparative Study;Journal Article
Narinx, Nick;Smismans, Annick;Symons, Rolf;Frans, Johan;Demeyere, Annick;Gillis, Marc
10.1007/s10140-020-01849-3
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Feasibility of using point-of-care lung ultrasound for early triage of COVID-19 patients in the emergency room. [Abstract]: PURPOSE: Diagnostic value of point-of-care lung ultrasound (POCUS) in detection of coronavirus disease (COVID-19) in an emergency setting is currently unclear. In this study, we aimed to ...
32,326,274
Int J Environ Res Public Health
Visiting Policies of Hospice Wards during the COVID-19 Pandemic: An Environmental Scan in Taiwan.
During an epidemic, almost all healthcare facilities restrict the visiting of patients to prevent disease transmission. For hospices with terminally ill patients, the trade-off between compassion and infection control becomes a difficult decision. This study aimed to survey the changes in visiting policy for all 76 hos...
covid-19;health care surveys;hospices;severe acute respiratory syndrome coronavirus 2;visitors to patients
Journal Article;Research Support, Non-U.S. Gov't
Hsu, Ya-Chuan;Liu, Ya-An;Lin, Ming-Hwai;Lee, Hsiao-Wen;Chen, Tzeng-Ji;Chou, Li-Fang;Hwang, Shinn-Jang
10.3390/ijerph17082857
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Visiting Policies of Hospice Wards during the COVID-19 Pandemic: An Environmental Scan in Taiwan. [Abstract]: During an epidemic, almost all healthcare facilities restrict the visiting of patients to prevent disease transmission. For hospices with terminally ill patients, the trade-off between compassion and i...
32,838,237
EClinicalMedicine
A country level analysis measuring the impact of government actions, country preparedness and socioeconomic factors on COVID-19 mortality and related health outcomes.
Background: A country level exploratory analysis was conducted to assess the impact of timing and type of national health policy/actions undertaken towards COVID-19 mortality and related health outcomes. Methods: Information on COVID-19 policies and health outcomes were extracted from websites and country specific sour...
covid-19;country-level analysis;public health policies
Journal Article
Chaudhry, Rabail;Dranitsaris, George;Mubashir, Talha;Bartoszko, Justyna;Riazi, Sheila
10.1016/j.eclinm.2020.100464
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: A country level analysis measuring the impact of government actions, country preparedness and socioeconomic factors on COVID-19 mortality and related health outcomes. [Abstract]: Background: A country level exploratory analysis was conducted to assess the impact of timing and type of national health policy/act...
33,048,980
PLoS One
Measurement of filtration efficiencies of healthcare and consumer materials using modified respirator fit tester setup.
During the current SARS-CoV-2 pandemic there is unprecedented demand for personal protective equipment (PPE), especially N95 respirators and surgical masks. The ability of SARS-CoV-2 to be transmitted via respiratory droplets from asymptomatic individuals has necessitated increased usage of both N95 respirators in the ...
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Long, Kenneth D;Woodburn, Elizabeth V;Berg, Ian C;Chen, Valerie;Scott, William S
10.1371/journal.pone.0240499
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Measurement of filtration efficiencies of healthcare and consumer materials using modified respirator fit tester setup. [Abstract]: During the current SARS-CoV-2 pandemic there is unprecedented demand for personal protective equipment (PPE), especially N95 respirators and surgical masks. The ability of SARS-Co...
32,904,494
Integr Pharm Res Pract
COVID-19-Related Knowledge, Attitude and Practice Among Hospital and Community Pharmacists in Addis Ababa, Ethiopia.
Purpose: This study was launched to assess COVID-19-related knowledge, attitude and practice among hospital and community pharmacists in Addis Ababa, Ethiopia. Methods: Self-administered questionnaire was distributed to pharmacists working in hospitals and community pharmacies by physically delivering the questionnaire...
sars-cov-2;global pandemic;novel coronavirus;physical distancing;viral pneumonia
Journal Article
Tesfaye, Zelalem Tilahun;Yismaw, Malede Berihun;Negash, Zenebe;Ayele, Akeberegn Gorems
10.2147/IPRP.S261275
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19-Related Knowledge, Attitude and Practice Among Hospital and Community Pharmacists in Addis Ababa, Ethiopia. [Abstract]: Purpose: This study was launched to assess COVID-19-related knowledge, attitude and practice among hospital and community pharmacists in Addis Ababa, Ethiopia. Methods: Self-administ...
32,362,678
Chem Eng Sci
Baculovirus transit through insect cell membranes: A mechanistic approach.
Baculovirus systems are used for various purposes, but the kinetics of the infection process is not fully understood yet. We investigated the dynamics of virion movement from a medium toward the interior of insect cells and established a mechanistic model that shows an excellent fit to experimental results. It also mak...
baculovirus;infection simulation;infection kinetics;mathematical model
Journal Article
Zhang, Youhong;Enden, Giora;Wei, Wei;Zhou, Feng;Chen, Jie;Merchuk, Jose C
10.1016/j.ces.2020.115727
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Baculovirus transit through insect cell membranes: A mechanistic approach. [Abstract]: Baculovirus systems are used for various purposes, but the kinetics of the infection process is not fully understood yet. We investigated the dynamics of virion movement from a medium toward the interior of insect cells and ...
32,522,845
Postgrad Med J
Managing hand and reconstructive microsurgery service during COVID-19 pandemic: Singapore experience.
INTRODUCTION: Managing healthcare service during pandemics and outbreaks is a challenging process. The aim is to keep patient safety as the priority, besides, continuing to provide essential healthcare services. METHODS: Situational audit was performed for the services rendered before and during COVID-19 pandemic and t...
hand & wrist;infection control;infectious diseases;limb reconstruction;plastic & reconstructive surgery;respiratory infections
Journal Article
Omar, Usama Farghaly;Pei Yein, Tong;Rajaratnam, Vaikunthan
10.1136/postgradmedj-2020-137735
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Managing hand and reconstructive microsurgery service during COVID-19 pandemic: Singapore experience. [Abstract]: INTRODUCTION: Managing healthcare service during pandemics and outbreaks is a challenging process. The aim is to keep patient safety as the priority, besides, continuing to provide essential health...
32,634,004
Afr J Prim Health Care Fam Med
The role of the family physician in the fight against Coronavirus disease 2019 in Nigeria.
The Coronavirus disease 2019 (COVID-19) pandemic has been ravaging Nigeria and the world with increasing morbidity and mortality. Despite efforts by the Nigerian government implemented through the Nigerian Centre for Disease Control (NCDC) to reduce the scourge of the disease through public enlightenment and regular up...
covid-19;nigeria;family physicians;frontline;pandemic
Journal Article
Oseni, Tijani I A;Agbede, Ramatu O;Fatusin, Bolatito B;Odewale, Michael A
10.4102/phcfm.v12i1.2492
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The role of the family physician in the fight against Coronavirus disease 2019 in Nigeria. [Abstract]: The Coronavirus disease 2019 (COVID-19) pandemic has been ravaging Nigeria and the world with increasing morbidity and mortality. Despite efforts by the Nigerian government implemented through the Nigerian Ce...
32,542,464
Can J Anaesth
High-flow nasal cannula for acute hypoxemic respiratory failure in patients with COVID-19: systematic reviews of effectiveness and its risks of aerosolization, dispersion, and infection transmission.
PURPOSE: We conducted two World Health Organization-commissioned reviews to inform use of high-flow nasal cannula (HFNC) in patients with coronavirus disease (COVID-19). We synthesized the evidence regarding efficacy and safety (review 1), as well as risks of droplet dispersion, aerosol generation, and associated trans...
covid-19;sars-cov-2;aerosols;high-flow nasal cannula;respiratory failure
Comparative Study;Journal Article;Systematic Review
Agarwal, Arnav;Basmaji, John;Muttalib, Fiona;Granton, David;Chaudhuri, Dipayan;Chetan, Devin;Hu, Malini;Fernando, Shannon M;Honarmand, Kimia;Bakaa, Layla;Brar, Sonia;Rochwerg, Bram;Adhikari, Neill K;Lamontagne, Francois;Murthy, Srinivas;Hui, David S C;Gomersall, Charles;Mubareka, Samira;Diaz, Janet V;Burns, Karen E A;C...
10.1007/s12630-020-01740-2
[ 1, 0, 1, 0, 1, 0, 0 ]
[Title]: High-flow nasal cannula for acute hypoxemic respiratory failure in patients with COVID-19: systematic reviews of effectiveness and its risks of aerosolization, dispersion, and infection transmission. [Abstract]: PURPOSE: We conducted two World Health Organization-commissioned reviews to inform use of high-flow...
32,811,627
J Subst Abuse Treat
Making lemonade from SARS coronavirus-2 lemons: Transitioning a smoking cessation trial to a virtual platform.
Clinical trials represent an essential component of improving treatment for substance use disorders (SUD). The SARS coronavirus-2 pandemic disrupted our ongoing clinical trial of smoking cessation and forced us to rapidly implement changes to assure participants access to ongoing counseling and monitoring via telephone...
Journal Article;Research Support, N.I.H., Extramural
Mahoney, Martin C;Ashare, Rebecca;Schlienz, Nicolas;Duerr, CeCe;Hawk, Larry W
10.1016/j.jsat.2020.108100
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Making lemonade from SARS coronavirus-2 lemons: Transitioning a smoking cessation trial to a virtual platform. [Abstract]: Clinical trials represent an essential component of improving treatment for substance use disorders (SUD). The SARS coronavirus-2 pandemic disrupted our ongoing clinical trial of smoking c...
32,387,564
Infect Genet Evol
Emergence of genomic diversity and recurrent mutations in SARS-CoV-2.
SARS-CoV-2 is a SARS-like coronavirus of likely zoonotic origin first identified in December 2019 in Wuhan, the capital of China's Hubei province. The virus has since spread globally, resulting in the currently ongoing COVID-19 pandemic. The first whole genome sequence was published on January 5 2020, and thousands of ...
betacoronavirus;homoplasies;mutation;phylogenetics
Journal Article
van Dorp, Lucy;Acman, Mislav;Richard, Damien;Shaw, Liam P;Ford, Charlotte E;Ormond, Louise;Owen, Christopher J;Pang, Juanita;Tan, Cedric C S;Boshier, Florencia A T;Ortiz, Arturo Torres;Balloux, Francois
10.1016/j.meegid.2020.104351
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Emergence of genomic diversity and recurrent mutations in SARS-CoV-2. [Abstract]: SARS-CoV-2 is a SARS-like coronavirus of likely zoonotic origin first identified in December 2019 in Wuhan, the capital of China's Hubei province. The virus has since spread globally, resulting in the currently ongoing COVID-19 p...
32,239,761
Allergy
COVID-19 in a designated infectious diseases hospital outside Hubei Province, China.
BACKGROUND: The clinical characteristics of novel coronavirus disease (COVID-2019) patients outside the epicenter of Hubei Province are less understood. METHODS: We analyzed the epidemiological and clinical features of all COVID-2019 cases in the only referral hospital in Shenzhen City, China, from January 11, 2020, to...
corona virus disease 2019;epidemiological features;severe acute respiratory syndrome coronavirus 2;severe pneumonia
Journal Article;Research Support, Non-U.S. Gov't
Cai, Qingxian;Huang, Deliang;Ou, Pengcheng;Yu, Hong;Zhu, Zhibin;Xia, Zhang;Su, Yinan;Ma, Zhenghua;Zhang, Yiming;Li, Zhiwei;He, Qing;Liu, Lei;Fu, Yang;Chen, Jun
10.1111/all.14309
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: COVID-19 in a designated infectious diseases hospital outside Hubei Province, China. [Abstract]: BACKGROUND: The clinical characteristics of novel coronavirus disease (COVID-2019) patients outside the epicenter of Hubei Province are less understood. METHODS: We analyzed the epidemiological and clinical feature...
32,527,928
Science
Type I and III interferons disrupt lung epithelial repair during recovery from viral infection.
Excessive cytokine signaling frequently exacerbates lung tissue damage during respiratory viral infection. Type I (IFN-alpha and IFN-beta) and III (IFN-lambda) interferons are host-produced antiviral cytokines. Prolonged IFN-alpha and IFN-beta responses can lead to harmful proinflammatory effects, whereas IFN-lambda ma...
Journal Article;Research Support, Non-U.S. Gov't
Major, Jack;Crotta, Stefania;Llorian, Miriam;McCabe, Teresa M;Gad, Hans Henrik;Priestnall, Simon L;Hartmann, Rune;Wack, Andreas
10.1126/science.abc2061
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Type I and III interferons disrupt lung epithelial repair during recovery from viral infection. [Abstract]: Excessive cytokine signaling frequently exacerbates lung tissue damage during respiratory viral infection. Type I (IFN-alpha and IFN-beta) and III (IFN-lambda) interferons are host-produced antiviral cyt...
33,055,189
BMJ Mil Health
Recovery of individual Service personnel in the COVID-19 recovery phase.
To deny the SARS-CoV-2 virus easy options for sustained transmission, commanders should model adherence to, and ensure implementation of, social mitigation measures. While some measures can be achieved at the organisational level through policy, every Service person's experience of the COVID-19 pandemic will have diffe...
infectious diseases;public health
Journal Article
Taylor, Hannah;Quantick, O;Ross, D
10.1136/bmjmilitary-2020-001603
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Recovery of individual Service personnel in the COVID-19 recovery phase. [Abstract]: To deny the SARS-CoV-2 virus easy options for sustained transmission, commanders should model adherence to, and ensure implementation of, social mitigation measures. While some measures can be achieved at the organisational le...
32,863,628
Indian J Crit Care Med
Preparedness of Acute Care Facility and a Hospital for COVID-19 Pandemic: What We Did!
Background and aim: India is facing the pandemic of coronavirus disease (COVID-19) just like the whole world. The private sector is the backbone of a healthcare facility in India. Presently, only a few major hospitals in the country are actively dealing with the COVID-19 patients while others are facing troubles due to...
covid pneumonia;intensive care unit;pandemic;preparedness
Journal Article
Jog, Sameer;Kelkar, Dhananjay;Bhat, Madhav;Patwardhan, Sampada;Godavarthy, Purushotham;Dhundi, Ujwal;Pawar, Harshwardhan S;Rajhans, Prasad;Pawar, Balasaheb;Telbhare, Vishnudas S;Ranade, Gouri;Upadhye, Vaibhavi;Prayag, Parikshit S;Purandare, Bharat;Purandare, Sukrut;Bhavsar, Rajesh
10.5005/jp-journals-10071-23416
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Preparedness of Acute Care Facility and a Hospital for COVID-19 Pandemic: What We Did! [Abstract]: Background and aim: India is facing the pandemic of coronavirus disease (COVID-19) just like the whole world. The private sector is the backbone of a healthcare facility in India. Presently, only a few major hosp...
32,953,353
Cureus
Frequency of Neurological Presentations of Coronavirus Disease in Patients Presenting to a Tertiary Care Hospital During the 2019 Coronavirus Disease Pandemic.
Background Coronavirus disease 2019 (COVID-19), caused by infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), usually presents clinically with cough, fever, shortness of breath, and loss of taste and/or smell. COVID-19 can also present with neurologic signs and symptoms, including headache,...
cerebro-vascular accident (stroke);coronavirus disease 2019 (covid-19);guillain-barre syndrome (gbs);polymerase chain reaction (pcr)
Journal Article
Iltaf, Samar Sr;Fatima, Meraj;Salman, Salma Sr;Salam, Jawwad-Us;Abbas, Saira
10.7759/cureus.9846
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Frequency of Neurological Presentations of Coronavirus Disease in Patients Presenting to a Tertiary Care Hospital During the 2019 Coronavirus Disease Pandemic. [Abstract]: Background Coronavirus disease 2019 (COVID-19), caused by infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), ...
32,175,797
Ocul Immunol Inflamm
Can the Coronavirus Disease 2019 (COVID-19) Affect the Eyes? A Review of Coronaviruses and Ocular Implications in Humans and Animals.
In December 2019, a novel coronavirus (CoV) epidemic, caused by the severe acute respiratory syndrome coronavirus - 2 (SARS-CoV-2) emerged from China. This virus causes the coronavirus disease 2019 (COVID-19). Since then, there have been anecdotal reports of ocular infection. The ocular implications of human CoV infect...
covid-19;coronavirus;coronavirus disease 2019;novel coronavirus;severe acute respiratory syndrome coronavirus-2
Journal Article;Review
Seah, Ivan;Agrawal, Rupesh
10.1080/09273948.2020.1738501
[ 0, 0, 0, 1, 1, 0, 0 ]
[Title]: Can the Coronavirus Disease 2019 (COVID-19) Affect the Eyes? A Review of Coronaviruses and Ocular Implications in Humans and Animals. [Abstract]: In December 2019, a novel coronavirus (CoV) epidemic, caused by the severe acute respiratory syndrome coronavirus - 2 (SARS-CoV-2) emerged from China. This virus cau...
32,376,593
Nan Fang Yi Ke Da Xue Xue Bao
[Liquid chromatography tandem mass spectrometry for therapeutic drug monitoring of voriconazole in heat-inactivated blood samples: its application during COVID-19 pandemic].
OBJECTIVE: To investigate the effect of heat inactivation (56for 30 min) of SARS-CoV-2 on the results of therapeuticdrug monitoring (TDM) of voriconazole by liquid chromatography tandem mass spectrometry (LC-MS/MS). METHODS: We collected clinical blood samples from voriconazole-treated patients in heparinized tubes and...
covid-19;therapeutic drug monitoring;voriconazole;whole blood inactivation
Journal Article
Zhao, Boxin;Liu, Sijia;Liu, Yuan;Li, Guofeng;Zhang, Qing
10.12122/j.issn.1673-4254.2020.03.08
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: [Liquid chromatography tandem mass spectrometry for therapeutic drug monitoring of voriconazole in heat-inactivated blood samples: its application during COVID-19 pandemic]. [Abstract]: OBJECTIVE: To investigate the effect of heat inactivation (56for 30 min) of SARS-CoV-2 on the results of therapeuticdrug moni...
32,709,055
Pathogens
Polymorphism and Selection Pressure of SARS-CoV-2 Vaccine and Diagnostic Antigens: Implications for Immune Evasion and Serologic Diagnostic Performance.
The ongoing SARS-CoV-2 pandemic has triggered multiple efforts for serological tests and vaccine development. Most of these tests and vaccines are based on the Spike glycoprotein (S) or the Nucleocapsid (N) viral protein. Conservation of these antigens among viral strains is critical to ensure optimum diagnostic test p...
antigenic drift;coronavirus;diversifying selection;diversity;immune evasion
Journal Article
Dumonteil, Eric;Herrera, Claudia
10.3390/pathogens9070584
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: Polymorphism and Selection Pressure of SARS-CoV-2 Vaccine and Diagnostic Antigens: Implications for Immune Evasion and Serologic Diagnostic Performance. [Abstract]: The ongoing SARS-CoV-2 pandemic has triggered multiple efforts for serological tests and vaccine development. Most of these tests and vaccines are...
32,838,033
Laryngoscope Investig Otolaryngol
Navigating telemedicine for facial trauma during the COVID-19 pandemic.
Importance: The COVID-19 pandemic is changing how health care providers practice. As some telemedicine and telecommunication support tools have been incorporated into the otolaryngology practice in response to safety and access demands, it is essential to review how these tools and services can help facilitate facial t...
covid-19;facial trauma;telemedicine
Journal Article
Said, Mena;Ngo, Victoria;Hwang, Joshua;Hom, David B
10.1002/lio2.428
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Navigating telemedicine for facial trauma during the COVID-19 pandemic. [Abstract]: Importance: The COVID-19 pandemic is changing how health care providers practice. As some telemedicine and telecommunication support tools have been incorporated into the otolaryngology practice in response to safety and access...
32,656,668
Inflamm Res
SARS-CoV-2 will constantly sweep its tracks: a vaccine containing CpG motifs in 'lasso' for the multi-faced virus.
During the current COVID-19 pandemic, the global ratio between the dead and the survivors is approximately 1 to 10, which has put humanity on high alert and provided strong motivation for the intensive search for vaccines and drugs. It is already clear that if we follow the most likely scenario, which is similar to tha...
covid-19 pandemic;cpg motif;phosphorothioate oligonucleotides;sars-cov-2;vaccine
Journal Article
Oberemok, V V;Laikova, K V;Yurchenko, K A;Marochkin, N A;Fomochkina, I I;Kubyshkin, A V
10.1007/s00011-020-01377-3
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: SARS-CoV-2 will constantly sweep its tracks: a vaccine containing CpG motifs in 'lasso' for the multi-faced virus. [Abstract]: During the current COVID-19 pandemic, the global ratio between the dead and the survivors is approximately 1 to 10, which has put humanity on high alert and provided strong motivation ...
32,837,666
J Cardiol Cases
Relative bradycardia as a clinical feature in patients with coronavirus disease 2019 (COVID-19): A report of two cases.
We treated two patients with COVID-19 pneumonia requiring mechanical ventilation. Case 1 was a 73-year-old Japanese man. Computed tomography (CT) revealed ground-glass opacities in both lungs. He had severe respiratory failure with a partial pressure of oxygen in arterial blood/fraction of inspiratory oxygen ratio (P/F...
coronavirus 2 (sars-cov-2);coronavirus disease 2019 (covid-19);myocardial injury;relative bradycardia;severe acute respiratory syndrome
Case Reports
Hiraiwa, Hiroaki;Goto, Yukari;Nakamura, Genki;Yasuda, Yuma;Sakai, Yoshinori;Kasugai, Daisuke;Jinno, Shinsuke;Tanaka, Taku;Ogawa, Hiroaki;Higashi, Michiko;Yamamoto, Takanori;Jingushi, Naruhiro;Ozaki, Masayuki;Numaguchi, Atsushi;Kondo, Toru;Morimoto, Ryota;Okumura, Takahiro;Matsuda, Naoyuki;Murohara, Toyoaki
10.1016/j.jccase.2020.07.015
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Relative bradycardia as a clinical feature in patients with coronavirus disease 2019 (COVID-19): A report of two cases. [Abstract]: We treated two patients with COVID-19 pneumonia requiring mechanical ventilation. Case 1 was a 73-year-old Japanese man. Computed tomography (CT) revealed ground-glass opacities i...
32,607,352
J Adv Vet Anim Res
Is the COVID-19 pandemic masking dengue epidemic in Bangladesh?
COVID-19 is now a pandemic. Like other countries, Bangladesh is putting all its efforts to combat this pandemic. Dengue is a mosquito-borne viral infection causing a severe flu-like illness and, sometimes causing a potentially lethal complication called severe dengue. At this very crisis moment, there are reports on ne...
covid-19;dengue;epidemic;preparedness
Editorial
Rahman, Md Tanvir;Sobur, Md Abdus;Islam, Md Saiful;Toniolo, Antonio;Nazir, K H M Nazmul Hussain
10.5455/javar.2020.g412
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Is the COVID-19 pandemic masking dengue epidemic in Bangladesh? [Abstract]: COVID-19 is now a pandemic. Like other countries, Bangladesh is putting all its efforts to combat this pandemic. Dengue is a mosquito-borne viral infection causing a severe flu-like illness and, sometimes causing a potentially lethal c...
32,909,898
J Intensive Care Med
The Role of Phosphodiesterase-5 Inhibitors in COVID-19: An Exploration of Literature From Similar Pathologies.
Coronavirus Disease 2019 (COVID-19) has had a devastating impact on the ability of highly trained healthcare providers to render sufficient care, due to both the significant demand on resources and the unique nature of this disease that make it resistant to traditional therapies. This review sought to determine the pot...
acute respiratory distress syndrome;acute lung injury;coronavirus disease 2019;high altitude pulmonary edema;phosphodiesterase-5 inhibitor;pulmonary arterial hypertension
Journal Article;Review
Reinert, Justin P;Reinert, Nathan J
10.1177/0885066620957951
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: The Role of Phosphodiesterase-5 Inhibitors in COVID-19: An Exploration of Literature From Similar Pathologies. [Abstract]: Coronavirus Disease 2019 (COVID-19) has had a devastating impact on the ability of highly trained healthcare providers to render sufficient care, due to both the significant demand on reso...
32,657,102
Nurs Stand
Tracheostomy care: the role of the nurse before, during and after insertion.
A tracheostomy is a surgical procedure that involves creating an opening and inserting a tube in the trachea to enable air transit from the external atmosphere to the lungs. The insertion of a tracheostomy is a common procedure used to wean patients from mechanical ventilation and to manage patients with upper respirat...
cardiorespiratory;clinical;mechanical ventilation;respiratory;temporary tracheostomy;tracheostomy;tracheostomy tube;ventilation
Journal Article
Flaherty, Cariona
10.7748/ns.2020.e11500
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Tracheostomy care: the role of the nurse before, during and after insertion. [Abstract]: A tracheostomy is a surgical procedure that involves creating an opening and inserting a tube in the trachea to enable air transit from the external atmosphere to the lungs. The insertion of a tracheostomy is a common proc...
32,845,150
J Chem Inf Model
De Novo Drug Design of Targeted Chemical Libraries Based on Artificial Intelligence and Pair-Based Multiobjective Optimization.
Artificial intelligence and multiobjective optimization represent promising solutions to bridge chemical and biological landscapes by addressing the automated de novo design of compounds as a result of a humanlike creative process. In the present study, we conceived a novel pair-based multiobjective approach implemente...
Journal Article
Domenico, Alberga;Nicola, Gambacorta;Daniela, Trisciuzzi;Fulvio, Ciriaco;Nicola, Amoroso;Orazio, Nicolotti
10.1021/acs.jcim.0c00517
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: De Novo Drug Design of Targeted Chemical Libraries Based on Artificial Intelligence and Pair-Based Multiobjective Optimization. [Abstract]: Artificial intelligence and multiobjective optimization represent promising solutions to bridge chemical and biological landscapes by addressing the automated de novo desi...