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32,619,669
Microb Pathog
Virtual screening based on molecular docking of possible inhibitors of Covid-19 main protease.
Coronavirus (COVID-19) is an enveloped RNA virus that is diversely found in humans and that has now been declared a global pandemic by the World Health Organization. Thus, there is an urgent need to develop effective therapies and vaccines against this disease. In this context, this study aimed to evaluate in silico th...
covid-19;inhibitors;molecular docking
Journal Article
Marinho, Emanuelle Machado;Batista de Andrade Neto, Joao;Silva, Jacilene;Rocha da Silva, Cecilia;Cavalcanti, Bruno Coelho;Marinho, Emmanuel Silva;Nobre Junior, Helio Vitoriano
10.1016/j.micpath.2020.104365
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Virtual screening based on molecular docking of possible inhibitors of Covid-19 main protease. [Abstract]: Coronavirus (COVID-19) is an enveloped RNA virus that is diversely found in humans and that has now been declared a global pandemic by the World Health Organization. Thus, there is an urgent need to devel...
32,851,855
Hypertension
Interaction of SARS-CoV-2 and Other Coronavirus With ACE (Angiotensin-Converting Enzyme)-2 as Their Main Receptor: Therapeutic Implications.
Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 originated from Wuhan, China, in December 2019 and rapidly spread to other areas worldwide. Since then, coronavirus disease 2019 (COVID-19) has reached pandemic proportions with >570 000 deaths globally by mid-July 2020. The magnitude of the outbreak and the po...
china;coronavirus;coronavirus infections;renin-angiotensin system;serine
Journal Article;Research Support, N.I.H., Extramural;Review
Davidson, Anne M;Wysocki, Jan;Batlle, Daniel
10.1161/HYPERTENSIONAHA.120.15256
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Interaction of SARS-CoV-2 and Other Coronavirus With ACE (Angiotensin-Converting Enzyme)-2 as Their Main Receptor: Therapeutic Implications. [Abstract]: Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 originated from Wuhan, China, in December 2019 and rapidly spread to other areas worldwide. Since t...
32,324,331
Am J Transplant
COVID-19 pneumonia in a kidney transplant recipient successfully treated with tocilizumab and hydroxychloroquine.
Coronavirus disease 2019 (COVID-19) pneumonia has been poorly reported in solid organ transplanted patients; prognosis is uncertain and best management unclear. We describe the case of a 61-year-old kidney transplant recipient with several comorbidities who was hospitalized and later received a diagnosis of COVID-19 pn...
clinical research/practice;immunosuppressant - fusion proteins and monoclonal antibodies;infection and infectious agents - viral;infectious disease;kidney transplantation/nephrology
Case Reports
Fontana, Francesco;Alfano, Gaetano;Mori, Giacomo;Amurri, Alessio;Tei, Lorenzo;Ballestri, Marco;Leonelli, Marco;Facchini, Francesca;Damiano, Francesca;Magistroni, Riccardo;Cappelli, Gianni
10.1111/ajt.15935
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: COVID-19 pneumonia in a kidney transplant recipient successfully treated with tocilizumab and hydroxychloroquine. [Abstract]: Coronavirus disease 2019 (COVID-19) pneumonia has been poorly reported in solid organ transplanted patients; prognosis is uncertain and best management unclear. We describe the case of ...
32,558,641
Med Sci (Paris)
[Coronavirus, emerging viruses].
Coronavirus is a large family of viruses that infect mammals and birds. Coronaviruses are known to cross barrier species and infect new ones. In the past twenty years, we witnessed the emergence of three different coronaviruses, the latest one being the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) respo...
Journal Article
Juckel, Dylan;Dubuisson, Jean;Belouzard, Sandrine
10.1051/medsci/2020113
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: [Coronavirus, emerging viruses]. [Abstract]: Coronavirus is a large family of viruses that infect mammals and birds. Coronaviruses are known to cross barrier species and infect new ones. In the past twenty years, we witnessed the emergence of three different coronaviruses, the latest one being the SARS-CoV-2 (...
32,458,565
J Intellect Disabil Res
Mortality of people with intellectual disabilities during the 2017/2018 influenza epidemic in the Netherlands: potential implications for the COVID-19 pandemic.
BACKGROUND: Data on the development of Covid-19 among people with intellectual disabilities (IDs) are scarce and it is uncertain to what extent general population data applies to people with ID. To give an indication of possible implications, this study investigated excess mortality patterns during a previous influenza...
epidemics;mortality;population data;virus infections
Journal Article;Research Support, Non-U.S. Gov't
Cuypers, M;Schalk, B W M;Koks-Leensen, M C J;Nagele, M E;Bakker-van Gijssel, E J;Naaldenberg, J;Leusink, G L
10.1111/jir.12739
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Mortality of people with intellectual disabilities during the 2017/2018 influenza epidemic in the Netherlands: potential implications for the COVID-19 pandemic. [Abstract]: BACKGROUND: Data on the development of Covid-19 among people with intellectual disabilities (IDs) are scarce and it is uncertain to what e...
32,594,606
Am J Transplant
Early national and center-level changes to kidney transplantation in the United States during the COVID-19 epidemic.
In March 2020, coronavirus disease 2019 (COVID-19) spread rapidly nationally, causing widespread emergent changes to the health system. Our goal was to understand the impact of the epidemic on kidney transplantation (KT), at both the national and center levels, accounting statistically for waitlist composition. Using S...
clinical research/practice;donors and donation: deceased;donors and donation: living;health services and outcomes research;infection and infectious agents - viral;infectious disease;kidney transplantation/nephrology;organ transplantation in general;patient survival;registry/registry analysis
Comparative Study;Journal Article;Multicenter Study;Research Support, N.I.H., Extramural
Boyarsky, Brian J;Werbel, William A;Durand, Christine M;Avery, Robin K;Jackson, Kyle R;Kernodle, Amber B;Snyder, Jon;Hirose, Ryutaro;Massie, Indraneel M;Garonzik-Wang, Jacqueline M;Segev, Dorry L;Massie, Allan B
10.1111/ajt.16167
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Early national and center-level changes to kidney transplantation in the United States during the COVID-19 epidemic. [Abstract]: In March 2020, coronavirus disease 2019 (COVID-19) spread rapidly nationally, causing widespread emergent changes to the health system. Our goal was to understand the impact of the e...
32,563,970
Med Hypotheses
Deceiving SARS-CoV-2 molecular-tropism clues - A combinational contemporary strategy.
Several attempts to control the dreadfulness of SARS-CoV-2 are still underway. Based on the literature evidences we have speculated a prospective contemporary remedy, which was categorized into Specificity, Remedy, and a Conveyor. In which, pros and cons were discussed and inferred the possible alternatives. (a) Specif...
ace2 receptors;ards;covid-19;coronavirus;molecular tropism;pulmonary surfactant;sars-cov-2
Journal Article
Balaji, Apb;Bhuvaneswari, Srinivasan;Kumar, D Nanda
10.1016/j.mehy.2020.109976
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Deceiving SARS-CoV-2 molecular-tropism clues - A combinational contemporary strategy. [Abstract]: Several attempts to control the dreadfulness of SARS-CoV-2 are still underway. Based on the literature evidences we have speculated a prospective contemporary remedy, which was categorized into Specificity, Remedy...
32,481,381
Medicine (Baltimore)
A case report with COVID-19 during perioperative period of lobectomy.
RATIONALE: Currently, COVID-19 has made a significant impact on many countries in the world. However, there have been no reported cases of pulmonary lobectomy with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2) infection. We are the first to report such a case. PATIENT CONCERNS: We report a 63-year-old Wu...
Case Reports;Journal Article
Han, Peng;Li, Fan;Cao, Peng;Hu, Shan;Kong, Kangle;Deng, Yu;Zu, Yukun;Zhao, Bo
10.1097/MD.0000000000020166
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: A case report with COVID-19 during perioperative period of lobectomy. [Abstract]: RATIONALE: Currently, COVID-19 has made a significant impact on many countries in the world. However, there have been no reported cases of pulmonary lobectomy with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2) infe...
32,405,190
J Clin Orthop Trauma
Orthopaedic resident management during the COVID-19 pandemic - AIIMS model.
The novel coronavirus disease (COVID-19) pandemic has had a tremendous impact on various health sectors including residency training programs. The suspension of non-essential health services at many hospitals has led to an increase in the workload for residents in emergency department while there was a sharp decline in...
aiims;covid;orthopaedic resident
Journal Article
Malhotra, Rajesh;Gautam, Deepak;George, Jaiben
10.1016/j.jcot.2020.05.001
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Orthopaedic resident management during the COVID-19 pandemic - AIIMS model. [Abstract]: The novel coronavirus disease (COVID-19) pandemic has had a tremendous impact on various health sectors including residency training programs. The suspension of non-essential health services at many hospitals has led to an ...
32,628,558
J Laparoendosc Adv Surg Tech A
Image-Guided Surgical e-Learning in the Post-COVID-19 Pandemic Era: What Is Next?
The current unprecedented coronavirus 2019 (COVID-19) crisis has accelerated and enhanced e-learning solutions. During the so-called transition phase, efforts were made to reorganize surgical services, reschedule elective surgical procedures, surgical research, academic education, and careers to optimize results. The i...
e-learning;online training;surgical education;surgical learning;training
Journal Article
Garcia Vazquez, Alain;Verde, Juan M;Dal Mas, Francesca;Palermo, Mariano;Cobianchi, Lorenzo;Marescaux, Jacques;Gallix, Benoit;Dallemagne, Bernard;Perretta, Silvana;Gimenez, Mariano E
10.1089/lap.2020.0535
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Image-Guided Surgical e-Learning in the Post-COVID-19 Pandemic Era: What Is Next? [Abstract]: The current unprecedented coronavirus 2019 (COVID-19) crisis has accelerated and enhanced e-learning solutions. During the so-called transition phase, efforts were made to reorganize surgical services, reschedule elec...
32,421,258
Acta Ophthalmol
Ocular manifestations and clinical characteristics of 535 cases of COVID-19 in Wuhan, China: a cross-sectional study.
PURPOSE: To investigate the ocular manifestations and clinical characteristics of COVID-19 patients caused by SARS-CoV-2 in Wuhan, China. METHODS: A total of 535 COVID-19 patients were recruited at Mobile Cabin Hospital and Tongji Hospital. Information on demographic characteristics, exposure history, ocular symptoms, ...
covid-19;sars-cov-2;conjunctival congestion;hand-eye contact;ocular manifestations
Journal Article
Chen, Liwen;Deng, Chaohua;Chen, Xuhui;Zhang, Xian;Chen, Bo;Yu, Huimin;Qin, Yuanjun;Xiao, Ke;Zhang, Hong;Sun, Xufang
10.1111/aos.14472
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: Ocular manifestations and clinical characteristics of 535 cases of COVID-19 in Wuhan, China: a cross-sectional study. [Abstract]: PURPOSE: To investigate the ocular manifestations and clinical characteristics of COVID-19 patients caused by SARS-CoV-2 in Wuhan, China. METHODS: A total of 535 COVID-19 patients w...
33,071,206
J Stroke Cerebrovasc Dis
Mitigating the effects of COVID-19 pandemic on controlling vascular risk factors among participants in a carotid stenosis trial.
INTRODUCTION: The COVID-19 pandemic has presented challenges to managing vascular risk factors with in-person follow-up of patients with asymptomatic carotid stenosis enrolled in the CREST2 trial. CREST2 is comparing intensive medical management alone versus intensive medical management plus revascularization with enda...
asymptomatic carotid stenosis;covid-19;coronavirus;risk factors
Clinical Trial;Journal Article;Multicenter Study
Turan, Tanya N;Meschia, James F;Chimowitz, Marc I;Roldan, Ana;LeMatty, Todd;Luke, Sothear;Breathitt, Linda;Eiland, Robin;Foley, Jon;Brott, Thomas G
10.1016/j.jstrokecerebrovasdis.2020.105362
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Mitigating the effects of COVID-19 pandemic on controlling vascular risk factors among participants in a carotid stenosis trial. [Abstract]: INTRODUCTION: The COVID-19 pandemic has presented challenges to managing vascular risk factors with in-person follow-up of patients with asymptomatic carotid stenosis enr...
32,832,308
Cureus
Patient Satisfaction With the Use of Telemedicine in the Management of Hyperthyroidism.
Introduction We have been using telemedicine in the management of hyperthyroidism since 2010. Although telemedicine has been used in different areas of healthcare management for several years, its importance was highlighted during the current coronavirus (COVID-19) pandemic. The aim of this survey was to assess patient...
hyperthyroidism;patient experience;patient satisfaction;patient-centered;questionnaires;survey;telecare;telemedicine;thyrotoxicosis
Journal Article
Kaur, Devinder;Galloway, Georgia K;Oyibo, Samson O
10.7759/cureus.9859
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Patient Satisfaction With the Use of Telemedicine in the Management of Hyperthyroidism. [Abstract]: Introduction We have been using telemedicine in the management of hyperthyroidism since 2010. Although telemedicine has been used in different areas of healthcare management for several years, its importance was...
32,694,291
Am J Gastroenterol
Impact of Clinical Pharmacists in Inflammatory Bowel Disease Centers During the COVID-19 Pandemic.
INTRODUCTION: To characterize the clinical pharmacists' impact on caring for patients with inflammatory bowel disease during COVID-19. METHODS: A clinical pharmacist's encounters between March 17 and April 14, 2020, were audited to determine encounter frequency and indication. RESULTS: The clinical pharmacist addressed...
Journal Article
Bhat, Shubha;Farraye, Francis A;Moss, Alan C
10.14309/ajg.0000000000000787
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Impact of Clinical Pharmacists in Inflammatory Bowel Disease Centers During the COVID-19 Pandemic. [Abstract]: INTRODUCTION: To characterize the clinical pharmacists' impact on caring for patients with inflammatory bowel disease during COVID-19. METHODS: A clinical pharmacist's encounters between March 17 and ...
32,240,634
Lancet Infect Dis
Estimates of the severity of coronavirus disease 2019: a model-based analysis.
BACKGROUND: In the face of rapidly changing data, a range of case fatality ratio estimates for coronavirus disease 2019 (COVID-19) have been produced that differ substantially in magnitude. We aimed to provide robust estimates, accounting for censoring and ascertainment biases. METHODS: We collected individual-case dat...
Journal Article;Research Support, Non-U.S. Gov't
Verity, Robert;Okell, Lucy C;Dorigatti, Ilaria;Winskill, Peter;Whittaker, Charles;Imai, Natsuko;Cuomo-Dannenburg, Gina;Thompson, Hayley;Walker, Patrick G T;Fu, Han;Dighe, Amy;Griffin, Jamie T;Baguelin, Marc;Bhatia, Sangeeta;Boonyasiri, Adhiratha;Cori, Anne;Cucunuba, Zulma;FitzJohn, Rich;Gaythorpe, Katy;Green, Will;Haml...
10.1016/S1473-3099(20)30243-7
[ 0, 0, 0, 0, 0, 1, 0 ]
[Title]: Estimates of the severity of coronavirus disease 2019: a model-based analysis. [Abstract]: BACKGROUND: In the face of rapidly changing data, a range of case fatality ratio estimates for coronavirus disease 2019 (COVID-19) have been produced that differ substantially in magnitude. We aimed to provide robust est...
32,826,520
Obstet Gynecol
Medical Education and Safety as Co-priorities in the Coronavirus Disease 2019 (COVID-19) Era: We Can Do Both.
As hospitals and medical schools confronted coronavirus disease 2019 (COVID-19), medical students were essentially restricted from all clinical work in an effort to prioritize their safety and the safety of others. One downstream effect of this decision was that students were designated as nonessential, in contrast to ...
Journal Article
Baecher-Lind, Laura;Fleming, Angela C;Bhargava, Rashmi;Cox, Susan M;Everett, Elise N;Graziano, Scott C;Katz, Nadine T;Sims, Shireen Madani;Morgan, Helen K;Morosky, Christopher M;Sonn, Tammy S;Sutton, Jill M;Royce, Celeste S
10.1097/AOG.0000000000004113
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Medical Education and Safety as Co-priorities in the Coronavirus Disease 2019 (COVID-19) Era: We Can Do Both. [Abstract]: As hospitals and medical schools confronted coronavirus disease 2019 (COVID-19), medical students were essentially restricted from all clinical work in an effort to prioritize their safety ...
32,661,074
J Med Ethics
Why continuing uncertainties are no reason to postpone challenge trials for coronavirus vaccines.
To counter the pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), some have proposed accelerating SARS-CoV-2 vaccine development through controlled human infection (or 'challenge') trials. These trials would involve the deliberate exposure of relatively few young, healthy volunteers to SAR...
clinical trials;ethics;philosophical ethics;research ethics
Journal Article;Research Support, N.I.H., Extramural
Steel, Robert;Buchak, Lara;Eyal, Nir
10.1136/medethics-2020-106501
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Why continuing uncertainties are no reason to postpone challenge trials for coronavirus vaccines. [Abstract]: To counter the pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), some have proposed accelerating SARS-CoV-2 vaccine development through controlled human infection (or 'ch...
32,825,816
BMC Med
Compassionate drug (mis)use during pandemics: lessons for COVID-19 from 2009.
BACKGROUND: New emerging infections have no known treatment. Assessing potential drugs for safety and efficacy enables clinicians to make evidence-based treatment decisions and contributes to overall outbreak control. However, it is difficult to launch clinical trials in the unpredictable environment of an outbreak. We...
clinical trial;h1n1;influenza;pandemic;systematic review
Journal Article;Research Support, Non-U.S. Gov't;Systematic Review
Rojek, Amanda M;Martin, Genevieve E;Horby, Peter W
10.1186/s12916-020-01732-5
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Compassionate drug (mis)use during pandemics: lessons for COVID-19 from 2009. [Abstract]: BACKGROUND: New emerging infections have no known treatment. Assessing potential drugs for safety and efficacy enables clinicians to make evidence-based treatment decisions and contributes to overall outbreak control. How...
32,920,544
Z Naturforsch C J Biosci
Dynamic analysis of the mathematical model of COVID-19 with demographic effects.
The coronavirus is currently extremely contagious for humankind, which is a zoonotic tropical disease. The pandemic is the largest in history, affecting almost the whole world. What makes the condition the worst of all is no specific effective treatment available. In this article, we present an extended and modified fo...
covid-19;homotopy method;mathematical model;mathematical model with and without control;pandemic
Journal Article
Faraz, Naeem;Khan, Yasir;Goufo, E F Doungmo;Anjum, Amna;Anjum, Ali
10.1515/znc-2020-0121
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Dynamic analysis of the mathematical model of COVID-19 with demographic effects. [Abstract]: The coronavirus is currently extremely contagious for humankind, which is a zoonotic tropical disease. The pandemic is the largest in history, affecting almost the whole world. What makes the condition the worst of all...
32,333,431
J Card Surg
The role of extracorporeal life support for patients with COVID-19: Preliminary results from a statewide experience.
OBJECTIVE: There is a paucity of clinical data on critically ill patients with COVID-19 requiring extracorporeal life support. METHODS: A statewide multi-institutional collaborative for COVID-19 patients was utilized to obtain clinical data on the first 10 critically ill COVID-19 patients who required extracorporeal me...
covid-19;ecmo;cardiogenic shock;coronavirus
Journal Article;Multicenter Study
Sultan, Ibrahim;Habertheuer, Andreas;Usman, Asad A;Kilic, Arman;Gnall, Eric;Friscia, Michael E;Zubkus, Dmitriy;Hirose, Hitoshi;Sanchez, Pablo;Okusanya, Olugbenga;Szeto, Wilson Y;Gutsche, Jacob
10.1111/jocs.14583
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: The role of extracorporeal life support for patients with COVID-19: Preliminary results from a statewide experience. [Abstract]: OBJECTIVE: There is a paucity of clinical data on critically ill patients with COVID-19 requiring extracorporeal life support. METHODS: A statewide multi-institutional collaborative ...
32,754,471
J Family Med Prim Care
COVID-19 pandemic: Clinical management protocols for cardiac disease patients at teaching institute in Western Rajasthan.
The world is facing the new pandemic COVID-19 caused by a novel coronavirus SARS-CoV-2. The demography and socio-economic condition are highly varied in different parts of the world. India also has braced itself to fight with this novel threat. Patients with COVID-19 may have primary cardiac involvement or may have ass...
covid-19;cardiac protocol;pandemic
Journal Article
Deora, Surender;Bhardwaj, Pankaj;Garg, Mahendra Kumar
10.4103/jfmpc.jfmpc_558_20
[ 1, 1, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 pandemic: Clinical management protocols for cardiac disease patients at teaching institute in Western Rajasthan. [Abstract]: The world is facing the new pandemic COVID-19 caused by a novel coronavirus SARS-CoV-2. The demography and socio-economic condition are highly varied in different parts of the w...
32,720,611
Kardiologiia
[Use of Statins, Anticoagulants, Antiaggregants and Antiarrhythmic Drugs in Patients With COVID-19. The Agreed Experts' Position of Russian Society of Cardiology, Eurasian Association of Therapists, National Society on Atherothrombosis, Societies of Experts in Urgent Cardiology, Eurasian Arrhythmology Association].
This article discusses relevant aspects in the treatment of patients with COVID-19. Up-to-date information about principles for administration of statins, antithrombotics, and antiarrhythmics is presented. The authors addressed in detail specific features of reversing heart rhythm disorders in patients with coronavirus...
Journal Article;Practice Guideline
Shlyakhto, Ye V;Arutyunov, G P;Belenkov, Yu N;Tarlovskaya, E I;Konradi, A O;Panchenko, E P;Yavelov, I S;Tereshchenko, S N;Ardashev, A V;Arutyunov, A G;Grigorieva, N Yu;Dzhunusbekova, G A;Drapkina, O M;Koziolova, N A;Komarov, A L;Kropacheva, E S;Malchikova, S V;Mitkovskaya, N P;Orlova, Ya A;Petrova, M M;Rebrov, A P;Sisa...
10.18087/cardio.2020.6.n1180
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: [Use of Statins, Anticoagulants, Antiaggregants and Antiarrhythmic Drugs in Patients With COVID-19. The Agreed Experts' Position of Russian Society of Cardiology, Eurasian Association of Therapists, National Society on Atherothrombosis, Societies of Experts in Urgent Cardiology, Eurasian Arrhythmology Associat...
32,271,598
Arch Iran Med
COVID-19 and Iranian Medical Students; A Survey on Their Related-Knowledge, Preventive Behaviors and Risk Perception.
BACKGROUND: Since December 2019, a novel coronavirus disease (COVID-19) began its journey around the world. Medical students, as frontline healthcare workers, are more susceptible to be infected by the virus. The aim of this study was to assess COVID-19 related knowledge, self-reported preventive behaviors and risk per...
covid-19;health behavior;knowledge;medical students;prevention and control;risk
Journal Article
Taghrir, Mohammad Hossein;Borazjani, Roham;Shiraly, Ramin
10.34172/aim.2020.06
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 and Iranian Medical Students; A Survey on Their Related-Knowledge, Preventive Behaviors and Risk Perception. [Abstract]: BACKGROUND: Since December 2019, a novel coronavirus disease (COVID-19) began its journey around the world. Medical students, as frontline healthcare workers, are more susceptible t...
32,342,242
Biomech Model Mechanobiol
Outbreak dynamics of COVID-19 in China and the United States.
On March 11, 2020, the World Health Organization declared the coronavirus disease 2019, COVID-19, a global pandemic. In an unprecedented collective effort, massive amounts of data are now being collected worldwide to estimate the immediate and long-term impact of this pandemic on the health system and the global econom...
covid-19;coronavirus;epidemiology modeling;network model;seir model
Journal Article
Peirlinck, Mathias;Linka, Kevin;Sahli Costabal, Francisco;Kuhl, Ellen
10.1007/s10237-020-01332-5
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: Outbreak dynamics of COVID-19 in China and the United States. [Abstract]: On March 11, 2020, the World Health Organization declared the coronavirus disease 2019, COVID-19, a global pandemic. In an unprecedented collective effort, massive amounts of data are now being collected worldwide to estimate the immedia...
32,458,121
Eur Arch Otorhinolaryngol
Indications and timing for tracheostomy in patients with SARS CoV2-related.
BACKGROUND: The indications and timing for tracheostomy in patients with SARS CoV2-related are controversial. PURPOSE: In a recent issue published in the European Archives of Otorhinolaryngology, Mattioli et al. published a short communication about tracheostomy timing in patients with COVID-19 (Coronavirus Disease 201...
covid-19;indications;sars cov2;timing;tracheostomy
Letter;Comment
Ferri, Emanuele;Boscolo Nata, Francesca;Pedruzzi, Barbara;Campolieti, Giovanni;Scotto di Clemente, Francesco;Baratto, Fabio;Cristalli, Giovanni
10.1007/s00405-020-06068-7
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Indications and timing for tracheostomy in patients with SARS CoV2-related. [Abstract]: BACKGROUND: The indications and timing for tracheostomy in patients with SARS CoV2-related are controversial. PURPOSE: In a recent issue published in the European Archives of Otorhinolaryngology, Mattioli et al. published a...
32,727,898
Proc Natl Acad Sci U S A
Timing social distancing to avert unmanageable COVID-19 hospital surges.
Following the April 16, 2020 release of the Opening Up America Again guidelines for relaxing coronavirus disease 2019 (COVID-19) social distancing policies, local leaders are concerned about future pandemic waves and lack robust strategies for tracking and suppressing transmission. Here, we present a strategy for trigg...
covid-19;cocooning;optimization;public health response;social distancing
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't;Research Support, U.S. Gov't, Non-P.H.S.
Duque, Daniel;Morton, David P;Singh, Bismark;Du, Zhanwei;Pasco, Remy;Meyers, Lauren Ancel
10.1073/pnas.2009033117
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Timing social distancing to avert unmanageable COVID-19 hospital surges. [Abstract]: Following the April 16, 2020 release of the Opening Up America Again guidelines for relaxing coronavirus disease 2019 (COVID-19) social distancing policies, local leaders are concerned about future pandemic waves and lack robu...
32,372,051
J Hum Genet
Bioinformatic prediction of potential T cell epitopes for SARS-Cov-2.
To control and prevent the current COVID-19 pandemic, the development of novel vaccines is an emergent issue. In addition, we need to develop tools that can measure/monitor T-cell and B-cell responses to know how our immune system is responding to this deleterious virus. However, little information is currently availab...
Journal Article
Kiyotani, Kazuma;Toyoshima, Yujiro;Nemoto, Kensaku;Nakamura, Yusuke
10.1038/s10038-020-0771-5
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Bioinformatic prediction of potential T cell epitopes for SARS-Cov-2. [Abstract]: To control and prevent the current COVID-19 pandemic, the development of novel vaccines is an emergent issue. In addition, we need to develop tools that can measure/monitor T-cell and B-cell responses to know how our immune syste...
32,890,937
J Clin Virol
Unexpected diagnosis of COVID-19-associated disorders by SARS-CoV-2-specific serology.
Facing the ongoing pandemic caused by SARS-CoV-2, there is an urgent need for serological assays identifying individuals with on-going infection as well as past coronavirus infectious disease 2019 (COVID-19). We herein evaluated the analytical performances of the CE IVD-labeled Abbott SARS-CoV-2 IgG assay (Des Plaines,...
abbott sars-cov-2 igg assay;covid-19;diagnosis;sars-cov-2;serology
Journal Article
Pere, Helene;Vedie, Benoit;Vernet, Raphael;Demory, Nathalie;Kassis, Najiby;Mirault, Tristan;Lazareth, Helene;Volle, Geoffroy;Denoix, Elsa;Lebeaux, David;Podglajen, Isabelle;Belec, Laurent;Veyer, David
10.1016/j.jcv.2020.104568
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Unexpected diagnosis of COVID-19-associated disorders by SARS-CoV-2-specific serology. [Abstract]: Facing the ongoing pandemic caused by SARS-CoV-2, there is an urgent need for serological assays identifying individuals with on-going infection as well as past coronavirus infectious disease 2019 (COVID-19). We ...
32,867,706
BMC Infect Dis
Epidemiologic, clinical, and laboratory findings of the COVID-19 in the current pandemic: systematic review and meta-analysis.
BACKGROUND: The COVID-19 pandemic has affected the world deeply, with more than 14,000,000 people infected and nearly 600,000 deaths. This review aimed to summarize the epidemiologic traits, clinical spectrum, CT results and laboratory findings of the COVID-19 pandemic. METHODS: We scoped for relevant literatures publi...
covid-19;clinical spectrum;epidemiology;laboratory findings;nature history
Journal Article;Meta-Analysis;Systematic Review
Xie, Yewei;Wang, Zaisheng;Liao, Huipeng;Marley, Gifty;Wu, Dan;Tang, Weiming
10.1186/s12879-020-05371-2
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Epidemiologic, clinical, and laboratory findings of the COVID-19 in the current pandemic: systematic review and meta-analysis. [Abstract]: BACKGROUND: The COVID-19 pandemic has affected the world deeply, with more than 14,000,000 people infected and nearly 600,000 deaths. This review aimed to summarize the epi...
32,891,063
J Clin Nurs
Older people's early experience of household isolation and social distancing during COVID-19.
AIM AND OBJECTIVE: To explore older people's initial experience of household isolation, social distancing and shielding, and the plans they constructed to support them through the COVID-19 pandemic. BACKGROUND: Public health guidance for those aged 70 or older was predominantly to undertake stringent social distancing ...
community care;older people;phenomenology;qualitative study
Journal Article
Brooke, Joanne;Clark, Maria
10.1111/jocn.15485
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Older people's early experience of household isolation and social distancing during COVID-19. [Abstract]: AIM AND OBJECTIVE: To explore older people's initial experience of household isolation, social distancing and shielding, and the plans they constructed to support them through the COVID-19 pandemic. BACKGR...
32,876,296
Rev Inst Med Trop Sao Paulo
Pregnancy and COVID-19: management and challenges.
The consequences of COVID-19 infecting pregnant women and the potential risks of vertical transmission have become a major issue. Since little is currently known about COVID-19 in pregnancy, the understanding of COVID-19 in this particular group will be updated in time, and a comprehensive review will be useful to eval...
Journal Article;Review
Wenling, Yao;Junchao, Qiu;Xiao, Zhirong;Ouyang, Shi
10.1590/s1678-9946202062062
[ 0, 1, 1, 0, 1, 0, 0 ]
[Title]: Pregnancy and COVID-19: management and challenges. [Abstract]: The consequences of COVID-19 infecting pregnant women and the potential risks of vertical transmission have become a major issue. Since little is currently known about COVID-19 in pregnancy, the understanding of COVID-19 in this particular group wi...
32,335,609
J Nepal Health Res Counc
Clinical Profile of Cases of COVID-19 in Far Western Province of Nepal.
The novel coronavirus (COVID-19) cause various symptoms such as pneumonia, fever, breathing difficult and lung infection. Till now, total 9 cases are reported in Nepal and 4 cases from this province. This case series is to describe the initial clinical features of COVID-19 among the patients admitted in isolation ward ...
Journal Article
Joshi, Jagadish;Mishra, Pradip;Kamar, Sher Bahadur;Sharma, Nirajan Datta;Parajuli, Janaki;Sharma, Seema;Pandey, Hem Raj
10.33314/jnhrc.v18i1.2602
[ 0, 1, 1, 0, 1, 0, 0 ]
[Title]: Clinical Profile of Cases of COVID-19 in Far Western Province of Nepal. [Abstract]: The novel coronavirus (COVID-19) cause various symptoms such as pneumonia, fever, breathing difficult and lung infection. Till now, total 9 cases are reported in Nepal and 4 cases from this province. This case series is to desc...
32,602,272
Diabetes Metab J
The Risk of Diabetes on Clinical Outcomes in Patients with Coronavirus Disease 2019: A Retrospective Cohort Study.
BACKGROUND: To determine the role of diabetes mellitus (DM) in the coronavirus disease 2019 (COVID-19), we explored the clinical characteristics of patients with DM and compared risk factors such as age, glycemic control, and medications to those without DM. METHODS: This was a retrospective cohort study of 117 confirm...
aged;covid-19;diabetes mellitus;prognosis;risk factors;severe acute respiratory syndrome coronavirus 2
Journal Article;Research Support, Non-U.S. Gov't
Chung, Seung Min;Lee, Yin Young;Ha, Eunyeong;Yoon, Ji Sung;Won, Kyu Chang;Lee, Hyoung Woo;Hur, Jian;Hong, Kyung Soo;Jang, Jong Geol;Jin, Hyun Jung;Choi, Eun Young;Shin, Kyeong Cheol;Chung, Jin Hong;Lee, Kwan Ho;Ahn, June Hong;Moon, Jun Sung
10.4093/dmj.2020.0105
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: The Risk of Diabetes on Clinical Outcomes in Patients with Coronavirus Disease 2019: A Retrospective Cohort Study. [Abstract]: BACKGROUND: To determine the role of diabetes mellitus (DM) in the coronavirus disease 2019 (COVID-19), we explored the clinical characteristics of patients with DM and compared risk f...
32,224,986
Int J Environ Res Public Health
Human Saliva: Non-Invasive Fluid for Detecting Novel Coronavirus (2019-nCoV).
The breakthrough of novel coronavirus (2019-nCoV) in Wuhan, a city of China, has damaged the status of health and quality of life. In the sequel of this epidemic or contagious disease, the patient experiences fever, chest paint, chills, a rapid heartbeat, breathing difficulties, pneumonia, and kidney failure. It has be...
2019-ncov;acute respiratory distress syndrome (ards);and covid-2019;diagnostics;point-of-care;saliva;severe acute respiratory syndrome (sers-cov);virus
Journal Article
Khurshid, Zohaib;Asiri, Faris Yahya Ibrahim;Al Wadaani, Hamed
10.3390/ijerph17072225
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Human Saliva: Non-Invasive Fluid for Detecting Novel Coronavirus (2019-nCoV). [Abstract]: The breakthrough of novel coronavirus (2019-nCoV) in Wuhan, a city of China, has damaged the status of health and quality of life. In the sequel of this epidemic or contagious disease, the patient experiences fever, chest...
32,433,162
Clin Nucl Med
FDG PET/CT in Diagnosing COVID-19 Infection in a Cancer Patient With Exposure History But Minimal Symptoms.
A 56-year-old woman with high-grade neuroendocrine small cell carcinoma had known contact history of COVID-19 about 16 days prior to the restaging PET/CT. The patient was instructed to self-quarantine for 14 days, and no COVID-19 test was performed. Upon arrival, the patient had low-grade fever of 37.1 degrees C, but d...
Case Reports;Journal Article
Chuang, Hubert H;Emery, Dustin J;Campbell, Richelle Millican;Lu, Yang
10.1097/RLU.0000000000003137
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: FDG PET/CT in Diagnosing COVID-19 Infection in a Cancer Patient With Exposure History But Minimal Symptoms. [Abstract]: A 56-year-old woman with high-grade neuroendocrine small cell carcinoma had known contact history of COVID-19 about 16 days prior to the restaging PET/CT. The patient was instructed to self-q...
32,869,556
Infect Chemother
A Universal Screening Strategy for SARS-CoV-2 Infection in Intensive Care Units: Korean Experience in a Single Hospital.
BACKGROUND: Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection is not differentiated clinically from other respiratory infections, and intensive care units (ICUs) are vulnerable to in-hospital transmission due to interventions inducing respiratory aerosols. This study evaluated the effectiveness of ...
covid;intensive care unit;nosocomial infection;sars-cov-2;screening
Journal Article
Chang, Euijin;Choi, Jae Sung;Park, Tae Yun;Kim, Seung Bin;Ko, Suhui;Kwon, Yang Sun;Kim, Eun Jin;Song, Hyunju;Noh, Hwa Kyung;Park, Sang Won
10.3947/ic.2020.52.3.352
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: A Universal Screening Strategy for SARS-CoV-2 Infection in Intensive Care Units: Korean Experience in a Single Hospital. [Abstract]: BACKGROUND: Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection is not differentiated clinically from other respiratory infections, and intensive care units (I...
32,622,952
Clin Microbiol Infect
Predictors of progression from moderate to severe coronavirus disease 2019: a retrospective cohort.
OBJECTIVE: Most cases of coronavirus disease 2019 (COVID-19) are identified as moderate, which is defined as having a fever or dry cough and lung imaging with ground-glass opacities. The risk factors and predictors of prognosis in such cohorts remain uncertain. METHODS: All adults with COVID-19 of moderate severity dia...
coronavirus disease 2019;moderate;neutrophil-lymphocyte ratio;predict;prognosis
Journal Article
Cheng, B;Hu, J;Zuo, X;Chen, J;Li, X;Chen, Y;Yang, G;Shi, X;Deng, A
10.1016/j.cmi.2020.06.033
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Predictors of progression from moderate to severe coronavirus disease 2019: a retrospective cohort. [Abstract]: OBJECTIVE: Most cases of coronavirus disease 2019 (COVID-19) are identified as moderate, which is defined as having a fever or dry cough and lung imaging with ground-glass opacities. The risk factors...
32,643,436
J Drug Target
Pharmacological and non-pharmacological efforts at prevention, mitigation, and treatment for COVID-19.
A global outbreak of the SARS-CoV-2 virus has infected millions of people over a short period of time. The communicability and increased mortality from the SARS-CoV-2 infection mandated the WHO to declare COVID-19 a worldwide pandemic. The virus outbreak has spread when there are no approved vaccines, treatments, or pr...
covid-19;sars-cov-2;antiviral;contact tracing;convalescent plasma;pandemic;personal protective equipment;social distancing;vaccine;ventilator support
Journal Article;Review
Alvi, Mohammed M;Sivasankaran, Sowmya;Singh, Mahima
10.1080/1061186X.2020.1793990
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Pharmacological and non-pharmacological efforts at prevention, mitigation, and treatment for COVID-19. [Abstract]: A global outbreak of the SARS-CoV-2 virus has infected millions of people over a short period of time. The communicability and increased mortality from the SARS-CoV-2 infection mandated the WHO to...
32,369,624
Hepatology
Coronavirus Disease 2019 Hangover: A Rising Tide of Alcohol Use Disorder and Alcohol-Associated Liver Disease.
The coronavirus disease 2019 (COVID-19) pandemic has had a tremendous global impact since it began in November of 2019. However, there are concerns that the COVID-19 pandemic will not affect all equally and that some populations will be particularly vulnerable. Relevant to liver disease, patients with alcohol use disor...
Journal Article
Da, Ben L;Im, Gene Y;Schiano, Thomas D
10.1002/hep.31307
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Coronavirus Disease 2019 Hangover: A Rising Tide of Alcohol Use Disorder and Alcohol-Associated Liver Disease. [Abstract]: The coronavirus disease 2019 (COVID-19) pandemic has had a tremendous global impact since it began in November of 2019. However, there are concerns that the COVID-19 pandemic will not affe...
32,520,580
AJR Am J Roentgenol
Diagnostic Ultrasound Services During the Coronavirus Disease (COVID-19) Pandemic.
OBJECTIVE. Nosocomial transmission of coronavirus disease (COVID-19) to frontline health care workers is well known, and health care workers may inadvertently become vectors for onward transmission. Ultrasound (US) service providers are at significant risk because scanning usually requires prolonged close patient conta...
covid-19;coronavirus disease;pandemic;personal protection equipment;pneumonia;ultrasound
Journal Article
Gogna, Apoorva;Yogendra, Praveen;Lee, Sally Hsueh Er;Aziz, Atiqah;Cheong, Elizabeth;Chan, Lai Peng;Venkatanarasimha, Nanda
10.2214/AJR.20.23167
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Diagnostic Ultrasound Services During the Coronavirus Disease (COVID-19) Pandemic. [Abstract]: OBJECTIVE. Nosocomial transmission of coronavirus disease (COVID-19) to frontline health care workers is well known, and health care workers may inadvertently become vectors for onward transmission. Ultrasound (US) s...
33,038,090
Clin J Sport Med
Interim Guidance on the Preparticipation Physical Examination for Athletes During the SARS-CoV-2 Pandemic.
The American Medical Society for Sports Medicine (AMSSM) convened a writing group to address the current evidence and knowledge gaps regarding preparticipation evaluation of athletes during the SARS-CoV2 pandemic. The writing group held a series of meetings beginning in April 2020. The task force reviewed the available...
Journal Article
Diamond, Alex B;Narducci, Dusty Marie;Roberts, William O;Bernhardt, David T;LaBella, Cynthia R;Moffatt, Kody A;Nuti, Rathna;Powell, Amy P;Rooks, Yvette L;Zaremski, Jason L
10.1097/JSM.0000000000000892
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Interim Guidance on the Preparticipation Physical Examination for Athletes During the SARS-CoV-2 Pandemic. [Abstract]: The American Medical Society for Sports Medicine (AMSSM) convened a writing group to address the current evidence and knowledge gaps regarding preparticipation evaluation of athletes during th...
32,510,102
J Nutr Health Aging
Editorial: Diagnostic Testing for SARS-Coronavirus-2 in the Nursing Facility: Recommendations of a Delphi Panel of Long-Term Care Clinicians.
With the COVID-19 pandemic progressing, guidance on strategies to mitigate its devastating effects in nursing facilities (NFs) is critical to preventing additional tragic outcomes. Asymptomatic spread of COVID-19 from nursing facility staff and residents is a major accelerator of infection. Facility-wide point-prevalen...
covid-19;coronavirus;nursing facilities;testing
Journal Article
Wasserman, M;Ouslander, J G;Lam, A;Wolk, A G;Morley, J E;von Preyss-Friedman, S;Marco, N;Nazir, A;Haimowitz, D;Bessey, F
10.1007/s12603-020-1401-9
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Editorial: Diagnostic Testing for SARS-Coronavirus-2 in the Nursing Facility: Recommendations of a Delphi Panel of Long-Term Care Clinicians. [Abstract]: With the COVID-19 pandemic progressing, guidance on strategies to mitigate its devastating effects in nursing facilities (NFs) is critical to preventing addi...
32,628,128
Clin Med (Lond)
COVID-19 and diabetes: What have we learned so far?
COVID-19 and diabetes are both pandemics with major impacts on global public health. While the response to COVID-19 has been rapid and progressive to reduce risk of harm, the response to the diabetes pandemic has been somewhat more muted. People with diabetes have been disproportionately affected by COVID-19, with grow...
covid-19;diabetes
Journal Article
Taher, Nida;Huda, Mohammed Sb;Chowdhury, Tahseen A
10.7861/clinmed.2020-0261
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 and diabetes: What have we learned so far? [Abstract]: COVID-19 and diabetes are both pandemics with major impacts on global public health. While the response to COVID-19 has been rapid and progressive to reduce risk of harm, the response to the diabetes pandemic has been somewhat more muted. People w...
32,594,966
Palliat Support Care
Healthcare utilization among breast cancer patients during the COVID-19 outbreak.
OBJECTIVE: Continuing to utilize healthcare as needed during an epidemic outbreak is significant, in general, and especially for cancer patients. Therefore, this study aimed to explore factors associated with health services utilization among breast cancer patients during the coronavirus disease (COVID-19) outbreak. ME...
anxiety;breast cancer;covid-19;coping resources;health services utilization;perceived susceptibility
Journal Article
Shinan-Altman, Shiri;Levkovich, Inbar;Tavori, Guy
10.1017/S1478951520000516
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Healthcare utilization among breast cancer patients during the COVID-19 outbreak. [Abstract]: OBJECTIVE: Continuing to utilize healthcare as needed during an epidemic outbreak is significant, in general, and especially for cancer patients. Therefore, this study aimed to explore factors associated with health s...
32,591,132
Ann Thorac Surg
The Rapid Transformation of Cardiac Surgery Practice in the Coronavirus Disease 2019 (COVID-19) Pandemic: Insights and Clinical Strategies From a Center at the Epicenter.
BACKGROUND: The onset of the coronavirus disease 2019 (COVID-19) pandemic has forced our cardiac surgery program and hospital to enact drastic measures that has forced us to change how we care for cardiac surgery patients, assist with COVID-19 care, and enable support for the hospital in terms of physical resources, pr...
Journal Article;Review
George, Isaac;Salna, Michael;Kobsa, Serge;Deroo, Scott;Kriegel, Jacob;Blitzer, David;Shea, Nicholas J;D'Angelo, Alex;Raza, Tasnim;Kurlansky, Paul;Takeda, Koji;Takayama, Hiroo;Bapat, Vinayak;Naka, Yoshifumi;Smith, Craig R;Bacha, Emile;Argenziano, Michael
10.1016/j.athoracsur.2020.04.012
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The Rapid Transformation of Cardiac Surgery Practice in the Coronavirus Disease 2019 (COVID-19) Pandemic: Insights and Clinical Strategies From a Center at the Epicenter. [Abstract]: BACKGROUND: The onset of the coronavirus disease 2019 (COVID-19) pandemic has forced our cardiac surgery program and hospital to...
32,253,891
Zhonghua Wai Ke Za Zhi
[Consideration of surgeons participating in 2019 coronavirus disease emergency medical rescue].
As a newly epidemic, 2019 coronavirus disease (COVID-19) with a concentrated outbreak poses a great challenge to medical treatment. The severe and critical patients are complex complicatied with the psychological problems, and the medical staff are overworked and under tremendous psychological pressure. The surgeon par...
2019 coronavirus disease;coronavirus infections;surgery
Journal Article
Li, S;Li, X D;Wang, G P;Liang, C;Jing, J P;Liu, M M;Zhang, C;Lin, T;Zhou, Y H;Song, Y Z;Tan, C;Wang, Q;Fan, L
10.3760/cma.j.cn112139-20200317-00226
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [Consideration of surgeons participating in 2019 coronavirus disease emergency medical rescue]. [Abstract]: As a newly epidemic, 2019 coronavirus disease (COVID-19) with a concentrated outbreak poses a great challenge to medical treatment. The severe and critical patients are complex complicatied with the psyc...
33,043,168
Clin Epidemiol Glob Health
Who is dying from COVID-19 and when? An Analysis of fatalities in Tamil Nadu, India.
Background: As the number of COVID-19 cases continues to rise, public health efforts must focus on preventing avoidable fatalities. Understanding the demographic and clinical characteristics of deceased COVID-19 patients; and estimation of time-interval between symptom onset, hospital admission and death could inform p...
age and sex-specific death rate;covid-19 in india;comorbidities of covid-19;time interval between infection and death
Journal Article
Asirvatham, Edwin Sam;Sarman, Charishma Jones;Saravanamurthy, Sakthivel P;Mahalingam, Periasamy;Maduraipandian, Swarna;Lakshmanan, Jeyaseelan
10.1016/j.cegh.2020.09.010
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Who is dying from COVID-19 and when? An Analysis of fatalities in Tamil Nadu, India. [Abstract]: Background: As the number of COVID-19 cases continues to rise, public health efforts must focus on preventing avoidable fatalities. Understanding the demographic and clinical characteristics of deceased COVID-19 pa...
32,838,287
Biosaf Health
Tackling COVID-19: Insights from the Qinghai Province plague prevention and control (PPC) model.
Plague, caused by Yersinia pestis, is a natural focus infectious disease. In China, plague is classified as category A, with the highest risk and hazard among the infectious diseases. Qinghai used to be considered as one of the most serious areas of plague in China. In recent years, thank to the measures in eight aspec...
covid-19;plague;public health;qinghai model
Journal Article
Wu, Haisheng;Zhang, Qingwen;Wu, Hailian;Tian, Fuzhang;Cui, Baizhong;Qi, Zhizhen;Xu, Xiaoqing;Zhang, Xuefei;Wang, Hu
10.1016/j.bsheal.2020.08.001
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Tackling COVID-19: Insights from the Qinghai Province plague prevention and control (PPC) model. [Abstract]: Plague, caused by Yersinia pestis, is a natural focus infectious disease. In China, plague is classified as category A, with the highest risk and hazard among the infectious diseases. Qinghai used to be...
32,599,338
Comput Methods Programs Biomed
Explainable Deep Learning for Pulmonary Disease and Coronavirus COVID-19 Detection from X-rays.
BACKGROUND AND OBJECTIVE: Coronavirus disease (COVID-19) is an infectious disease caused by a new virus never identified before in humans. This virus causes respiratory disease (for instance, flu) with symptoms such as cough, fever and, in severe cases, pneumonia. The test to detect the presence of this virus in humans...
artificial intelligence;covid-19;chest;coronavirus;deep learning;transfer learning
Journal Article
Brunese, Luca;Mercaldo, Francesco;Reginelli, Alfonso;Santone, Antonella
10.1016/j.cmpb.2020.105608
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Explainable Deep Learning for Pulmonary Disease and Coronavirus COVID-19 Detection from X-rays. [Abstract]: BACKGROUND AND OBJECTIVE: Coronavirus disease (COVID-19) is an infectious disease caused by a new virus never identified before in humans. This virus causes respiratory disease (for instance, flu) with s...
32,527,987
Aging (Albany NY)
Potential mechanisms of hemorrhagic stroke in elderly COVID-19 patients.
The novel severe acute respiratory syndrome coronavirus 2 is the causative agent of coronavirus disease 2019, a new human infectious disease. While fever, cough, and respiratory distress are typical first symptoms, a fraction of those affected present instead with neurological symptoms suggestive of central nervous sys...
ace2;covid-19;sars-cov-2;hemorrhagic stroke;immunity
Journal Article;Research Support, Non-U.S. Gov't;Review
Wang, Haili;Tang, Xiaojia;Fan, Hongyang;Luo, Yuhan;Song, Yuxia;Xu, Yao;Chen, Yingzhu
10.18632/aging.103335
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Potential mechanisms of hemorrhagic stroke in elderly COVID-19 patients. [Abstract]: The novel severe acute respiratory syndrome coronavirus 2 is the causative agent of coronavirus disease 2019, a new human infectious disease. While fever, cough, and respiratory distress are typical first symptoms, a fraction ...
32,873,230
BMC Infect Dis
Clinical and imaging findings of discharged patients with SARS-CoV-2 positive anal swab samples: a descriptive study.
BACKGROUND: To explore the clinical features and CT findings of clinically cured coronavirus disease 2019 (COVID-19) patients with viral RNA positive anal swab results after discharge. METHODS: Forty-two patients with COVID-19 who were admitted to Yongzhou Central Hospital, Hunan, China, between January 20, 2020, and M...
anal swab;covid-19;ct scan;discharged patients
Journal Article
Zhou, Hui;Zhu, Liping;Leng, Yueshuang;Wang, Dongcui;Bai, Harrison X;Xiong, Zeng;Shi, Linbo;Liao, Weihua
10.1186/s12879-020-05363-2
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical and imaging findings of discharged patients with SARS-CoV-2 positive anal swab samples: a descriptive study. [Abstract]: BACKGROUND: To explore the clinical features and CT findings of clinically cured coronavirus disease 2019 (COVID-19) patients with viral RNA positive anal swab results after dischar...
32,659,126
Expert Opin Pharmacother
Pharmacotherapeutic considerations in solid organ transplant patients with COVID-19.
INTRODUCTION: Coronavirus disease 2019 (COVID-19) has spread rapidly worldwide. While there are presently a few case reports/series on COVID-19 amongst solid organ transplant (SOT) patients, there is no official guideline for the management of SOT patients. AREAS COVERED: The authors discuss the pharmacotherapeutic man...
covid-19;coronavirus disease 2019;drug interaction;solid organ transplantation
Journal Article
Dashti-Khavidaki, Simin;Mohammadi, Keyhan;Khalili, Hossein;Abdollahi, Azin
10.1080/14656566.2020.1790526
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Pharmacotherapeutic considerations in solid organ transplant patients with COVID-19. [Abstract]: INTRODUCTION: Coronavirus disease 2019 (COVID-19) has spread rapidly worldwide. While there are presently a few case reports/series on COVID-19 amongst solid organ transplant (SOT) patients, there is no official gu...
32,513,865
Science
Genomic surveillance reveals multiple introductions of SARS-CoV-2 into Northern California.
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally, with >365,000 cases in California as of 17 July 2020. We investigated the genomic epidemiology of SARS-CoV-2 in Northern California from late January to mid-March 2020, using samp...
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Deng, Xianding;Gu, Wei;Federman, Scot;du Plessis, Louis;Pybus, Oliver G;Faria, Nuno R;Wang, Candace;Yu, Guixia;Bushnell, Brian;Pan, Chao-Yang;Guevara, Hugo;Sotomayor-Gonzalez, Alicia;Zorn, Kelsey;Gopez, Allan;Servellita, Venice;Hsu, Elaine;Miller, Steve;Bedford, Trevor;Greninger, Alexander L;Roychoudhury, Pavitra;Stari...
10.1126/science.abb9263
[ 0, 0, 1, 1, 0, 0, 0 ]
[Title]: Genomic surveillance reveals multiple introductions of SARS-CoV-2 into Northern California. [Abstract]: The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally, with >365,000 cases in California as of 17 July 2020. We investiga...
32,426,755
Crit Care Explor
Clinical Distancing and Mitigation of Coronavirus Disease 2019.
Social distancing as a technique to limit transmission of infectious disease has come into common parlance following the arrival and rapid spread of a novel coronavirus disease around the world in 2019 and 2020. But in the face of an emerging pandemic threat, it is crucial that we start to apply these principles to the...
clinical distancing;coronavirus disease 2019;social distancing;telemedicine
Journal Article
Scott, Benjamin K;Hravnak, Marilyn;Pamplin, Jeremy C
10.1097/CCE.0000000000000117
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Clinical Distancing and Mitigation of Coronavirus Disease 2019. [Abstract]: Social distancing as a technique to limit transmission of infectious disease has come into common parlance following the arrival and rapid spread of a novel coronavirus disease around the world in 2019 and 2020. But in the face of an e...
33,006,622
JAMA Netw Open
Use and Content of Primary Care Office-Based vs Telemedicine Care Visits During the COVID-19 Pandemic in the US.
Importance: Little is known about the association between the coronavirus disease 2019 (COVID-19) pandemic and the level and content of primary care delivery in the US. Objective: To quantify national changes in the volume, type, and content of primary care delivered during the COVID-19 pandemic, especially with regard...
Comparative Study;Journal Article
Alexander, G Caleb;Tajanlangit, Matthew;Heyward, James;Mansour, Omar;Qato, Dima M;Stafford, Randall S
10.1001/jamanetworkopen.2020.21476
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Use and Content of Primary Care Office-Based vs Telemedicine Care Visits During the COVID-19 Pandemic in the US. [Abstract]: Importance: Little is known about the association between the coronavirus disease 2019 (COVID-19) pandemic and the level and content of primary care delivery in the US. Objective: To qua...
32,876,569
Diagn Interv Radiol
Visual and software-based quantitative chest CT assessment of COVID-19: correlation with clinical findings.
PURPOSE: The aim of this study was to evaluate visual and software-based quantitative assessment of parenchymal changes and normal lung parenchyma in patients with coronavirus disease 2019 (COVID-19) pneumonia. The secondary aim of the study was to compare the radiologic findings with clinical and laboratory data. METH...
Evaluation Study;Journal Article
Durhan, Gamze;Ardali Duzgun, Selin;Basaran Demirkazik, Figen;Irmak, Ilim;Idilman, Ilkay;Gulsun Akpinar, Meltem;Akpinar, Erhan;Ocal, Serpil;Telli, Gulcin;Topeli, Arzu;Ariyurek, Orhan Macit
10.5152/dir.2020.20407
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Visual and software-based quantitative chest CT assessment of COVID-19: correlation with clinical findings. [Abstract]: PURPOSE: The aim of this study was to evaluate visual and software-based quantitative assessment of parenchymal changes and normal lung parenchyma in patients with coronavirus disease 2019 (C...
32,534,633
Lancet Oncol
Recommendations for head and neck surgical oncology practice in a setting of acute severe resource constraint during the COVID-19 pandemic: an international consensus.
The speed and scale of the global COVID-19 pandemic has resulted in unprecedented pressures on health services worldwide, requiring new methods of service delivery during the health crisis. In the setting of severe resource constraint and high risk of infection to patients and clinicians, there is an urgent need to ide...
Journal Article;Research Support, Non-U.S. Gov't;Review
Mehanna, Hisham;Hardman, John C;Shenson, Jared A;Abou-Foul, Ahmad K;Topf, Michael C;AlFalasi, Mohammad;Chan, Jason Y K;Chaturvedi, Pankaj;Chow, Velda Ling Yu;Dietz, Andreas;Fagan, Johannes J;Godballe, Christian;Golusinski, Wojciech;Homma, Akihiro;Hosal, Sefik;Iyer, N Gopalakrishna;Kerawala, Cyrus;Koh, Yoon Woo;Konney, ...
10.1016/S1470-2045(20)30334-X
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Recommendations for head and neck surgical oncology practice in a setting of acute severe resource constraint during the COVID-19 pandemic: an international consensus. [Abstract]: The speed and scale of the global COVID-19 pandemic has resulted in unprecedented pressures on health services worldwide, requiring...
32,554,251
Biomed Pharmacother
Protection against COVID-19 injury by qingfei paidu decoction via anti-viral, anti-inflammatory activity and metabolic programming.
Qingfei Paidu decoction (QFPD), a multi-component herbal formula, has been widely used to treat COVID-19 in China. However, its active compounds and mechanisms of action are still unknown. Firstly, we divided QFPD into five functional units (FUs) according to the compatibility theory of traditional Chinese medicine. Th...
anti-inflammatory;anti-viral;covid-19;functional units of network pharmacology;metabolic programming;qingfei paidu decoction
Journal Article
Chen, Jian;Wang, Yong-Kui;Gao, Yuan;Hu, Ling-San;Yang, Jiang-Wei;Wang, Jian-Ru;Sun, Wen-Jie;Liang, Zhi-Qiang;Cao, Ye-Min;Cao, Yong-Bing
10.1016/j.biopha.2020.110281
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Protection against COVID-19 injury by qingfei paidu decoction via anti-viral, anti-inflammatory activity and metabolic programming. [Abstract]: Qingfei Paidu decoction (QFPD), a multi-component herbal formula, has been widely used to treat COVID-19 in China. However, its active compounds and mechanisms of acti...
32,840,571
Clin Infect Dis
Two fatal cases of acute liver failure due to HSV-1 infection in COVID-19 patients following immunomodulatory therapies.
We reported two fatal cases of acute liver failure secondary to Herpes Simplex Virus 1 infection in COVID-19 patients, following tocilizumab and corticosteroid therapy.Screening for and prompt recognition of Herpes Simplex Virus 1 reactivation in these patients, undergoing immunomodulatory treatment, may have potential...
Journal Article
Busani, Stefano;Bedini, Andrea;Biagioni, Emanuela;Serio, Lucia;Tonelli, Roberto;Meschiari, Marianna;Franceschini, Erica;Guaraldi, Giovanni;Cossarizza, Andrea;Clini, Enrico;Maiorana, Antonino;Gennari, William;De Maria, Nicola;Luppi, Mario;Mussini, Cristina;Girardis, Massimo
10.1093/cid/ciaa1246
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Two fatal cases of acute liver failure due to HSV-1 infection in COVID-19 patients following immunomodulatory therapies. [Abstract]: We reported two fatal cases of acute liver failure secondary to Herpes Simplex Virus 1 infection in COVID-19 patients, following tocilizumab and corticosteroid therapy.Screening ...
33,026,453
JAMA Netw Open
Analysis of Genomic Characteristics and Transmission Routes of Patients With Confirmed SARS-CoV-2 in Southern California During the Early Stage of the US COVID-19 Pandemic.
Importance: In late December 2019, an outbreak of a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China. Data on the routes of transmission to Los Angeles, California, the US West Coast epicenter for coronavirus disease 2019 (COVID-19), and subsequent community spread are limited....
Journal Article;Research Support, Non-U.S. Gov't
Zhang, Wenjuan;Govindavari, John Paul;Davis, Brian D;Chen, Stephanie S;Kim, Jong Taek;Song, Jianbo;Lopategui, Jean;Plummer, Jasmine T;Vail, Eric
10.1001/jamanetworkopen.2020.24191
[ 0, 0, 0, 1, 1, 0, 0 ]
[Title]: Analysis of Genomic Characteristics and Transmission Routes of Patients With Confirmed SARS-CoV-2 in Southern California During the Early Stage of the US COVID-19 Pandemic. [Abstract]: Importance: In late December 2019, an outbreak of a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged...
32,105,637
Lancet Infect Dis
Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study.
BACKGROUND: A cluster of patients with coronavirus disease 2019 (COVID-19) pneumonia caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were successively reported in Wuhan, China. We aimed to describe the CT findings across different timepoints throughout the disease course. METHODS: ...
Journal Article
Shi, Heshui;Han, Xiaoyu;Jiang, Nanchuan;Cao, Yukun;Alwalid, Osamah;Gu, Jin;Fan, Yanqing;Zheng, Chuansheng
10.1016/S1473-3099(20)30086-4
[ 0, 1, 0, 1, 0, 0, 0 ]
[Title]: Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study. [Abstract]: BACKGROUND: A cluster of patients with coronavirus disease 2019 (COVID-19) pneumonia caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were successively reported ...
32,413,330
Immunity
Detection of SARS-CoV-2-Specific Humoral and Cellular Immunity in COVID-19 Convalescent Individuals.
The World Health Organization has declared SARS-CoV-2 virus outbreak a worldwide pandemic. However, there is very limited understanding on the immune responses, especially adaptive immune responses to SARS-CoV-2 infection. Here, we collected blood from COVID-19 patients who have recently become virus-free, and therefor...
covid-19 patients;sars-cov-2;sars-cov-2-specific t cells;sars-cov-2-specific antibody;adaptive immunity
Journal Article
Ni, Ling;Ye, Fang;Cheng, Meng-Li;Feng, Yu;Deng, Yong-Qiang;Zhao, Hui;Wei, Peng;Ge, Jiwan;Gou, Mengting;Li, Xiaoli;Sun, Lin;Cao, Tianshu;Wang, Pengzhi;Zhou, Chao;Zhang, Rongrong;Liang, Peng;Guo, Han;Wang, Xinquan;Qin, Cheng-Feng;Chen, Fang;Dong, Chen
10.1016/j.immuni.2020.04.023
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Detection of SARS-CoV-2-Specific Humoral and Cellular Immunity in COVID-19 Convalescent Individuals. [Abstract]: The World Health Organization has declared SARS-CoV-2 virus outbreak a worldwide pandemic. However, there is very limited understanding on the immune responses, especially adaptive immune responses ...
32,966,283
PLoS Negl Trop Dis
The COVID-19 pandemic should not jeopardize dengue control.
The concurrent circulation of dengue and coronavirus disease 2019 (COVID-19) may produce many unfavourable outcomes-such as co-infections; delays in diagnosis, treatment, and mitigation measures; overwhelming of the healthcare system; underreporting of cases; deterioration in surveillance and control interventions; and...
Journal Article;Research Support, Non-U.S. Gov't
Olive, Marie-Marie;Baldet, Thierry;Devillers, James;Fite, Johanna;Paty, Marie-Claire;Paupy, Christophe;Quenel, Philippe;Quillery, Elsa;Raude, Jocelyn;Stahl, Jean-Paul;Thiann-Bo-Morel, Marie;Roiz, David
10.1371/journal.pntd.0008716
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The COVID-19 pandemic should not jeopardize dengue control. [Abstract]: The concurrent circulation of dengue and coronavirus disease 2019 (COVID-19) may produce many unfavourable outcomes-such as co-infections; delays in diagnosis, treatment, and mitigation measures; overwhelming of the healthcare system; unde...
32,883,081
J Proteome Res
A Chain Only as Strong as Its Weakest Link: An Up-to-Date Literature Review on the Bidirectional Interaction of Pulmonary Fibrosis and COVID-19.
The COVID-19 pandemic rapidly became a worldwide healthcare emergency affecting millions of people, with poor outcomes for patients with chronic conditions and enormous pressure on healthcare systems. Pulmonary fibrosis (PF) has been cited as a risk factor for a more severe evolution of COVID-19, primarily because its ...
covid-19;antifibrotic medication;fibrosis pathways;prognosis;pulmonary fibrosis
Journal Article;Review
Crisan-Dabija, Radu;Pavel, Cristina Alice;Popa, Iolanda Valentina;Tarus, Andrei;Burlacu, Alexandru
10.1021/acs.jproteome.0c00387
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: A Chain Only as Strong as Its Weakest Link: An Up-to-Date Literature Review on the Bidirectional Interaction of Pulmonary Fibrosis and COVID-19. [Abstract]: The COVID-19 pandemic rapidly became a worldwide healthcare emergency affecting millions of people, with poor outcomes for patients with chronic condition...
32,616,067
Trials
ChemoPROphyLaxIs with hydroxychloroquine For covId-19 infeCtious disease (PROLIFIC) to prevent covid-19 infection in frontline healthcare workers: A structured summary of a study protocol for a randomised controlled trial.
OBJECTIVES: PRIMARY OBJECTIVE: To determine whether chemoprophylaxis with hydroxychloroquine versus placebo increases time to contracting coronavirus disease 2019 (COVID-19) in frontline healthcare workers. SECONDARY OBJECTIVES: 1) To determine whether chemoprophylaxis with daily versus weekly dosing of hydroxychloroqu...
covid-19;chemoprophylaxis;daily-dosing;healthcare workers;hydroxychloroquine;placebo;protocol;randomised controlled trial;weekly-dosing
Clinical Trial Protocol;Letter
McEniery, Carmel M;Fisk, Marie;Miles, Karen;Kaloyirou, Fotini;Hubsch, Annette;Smith, Jane;Wilkinson, Ian B;Cheriyan, Joseph
10.1186/s13063-020-04543-4
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: ChemoPROphyLaxIs with hydroxychloroquine For covId-19 infeCtious disease (PROLIFIC) to prevent covid-19 infection in frontline healthcare workers: A structured summary of a study protocol for a randomised controlled trial. [Abstract]: OBJECTIVES: PRIMARY OBJECTIVE: To determine whether chemoprophylaxis with hy...
32,369,475
Rev Gastroenterol Peru
[Recommendations of the Society of Gastroenterology of Peru to avoid the spread of SARS-CoV-2 through digestive endoscopy procedures].
The SARS-CoV-2 coronavirus produces the disease called COVID-19, currently spreading in a rapidly evolving pandemic. It can be transmitted by contact, drops and aerosols, and has been isolated from gastrointestinal secretions and faeces. During digestive endoscopy, transmission by any of these mechanisms could occur. I...
Journal Article;Practice Guideline
Prochazka Za Rate, Ricardo Arturo;Cabrera Cabrejos, Maria Cecilia;Piscoya, Alejandro;Vera Calderon, Augusto Francisco
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [Recommendations of the Society of Gastroenterology of Peru to avoid the spread of SARS-CoV-2 through digestive endoscopy procedures]. [Abstract]: The SARS-CoV-2 coronavirus produces the disease called COVID-19, currently spreading in a rapidly evolving pandemic. It can be transmitted by contact, drops and aer...
32,571,532
Chin J Traumatol
Surgical treatment of thoracolumbar fracture with incomplete lower limb paralysis in a patient with COVID-19.
Since December 2019, COVID-19, an acute infectious disease, has gradually become a global threat. We report a case of thoracolumbar fractures (T12 and L1) and incomplete lower limb paralysis in a patient with COVID-19. After a series of conservative treatment which did not work at all, posterior open reduction and pedi...
covid-19;cytokine storm;surgery;vertebrate fracture
Case Reports
Cao, Yu-Lin;Han, Yan-Jiu;Chen, Peng;Liu, Ze-Ming;Mutar, Muradil;Gao, Yong;Shao, Zeng-Wu;Tong, Wei;Liu, Yong
10.1016/j.cjtee.2020.05.005
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Surgical treatment of thoracolumbar fracture with incomplete lower limb paralysis in a patient with COVID-19. [Abstract]: Since December 2019, COVID-19, an acute infectious disease, has gradually become a global threat. We report a case of thoracolumbar fractures (T12 and L1) and incomplete lower limb paralysi...
32,361,911
Sci China Life Sci
Single-cell transcriptome analysis of the novel coronavirus (SARS-CoV-2) associated gene ACE2 expression in normal and non-obstructive azoospermia (NOA) human male testes.
Being infected by SARS-CoV-2 may cause damage to multiple organs in patients, such as the lung, liver and heart. Angiotensin-converting enzyme 2 (ACE2), reported as a SARS-CoV-2 receptor, is also expressed in human male testes. This suggests a potential risk in human male reproductive system. However, the characteristi...
ace2;covid-19;noa;sars-cov-2;tmprss2;adult;fetal;normal;testis cells
Journal Article
Liu, Xixi;Chen, Yidong;Tang, Wenhao;Zhang, Li;Chen, Wei;Yan, Zhiqiang;Yuan, Peng;Yang, Ming;Kong, Siming;Yan, Liying;Qiao, Jie
10.1007/s11427-020-1705-0
[ 0, 1, 0, 1, 0, 0, 0 ]
[Title]: Single-cell transcriptome analysis of the novel coronavirus (SARS-CoV-2) associated gene ACE2 expression in normal and non-obstructive azoospermia (NOA) human male testes. [Abstract]: Being infected by SARS-CoV-2 may cause damage to multiple organs in patients, such as the lung, liver and heart. Angiotensin-co...
32,865,490
Dtsch Arztebl Int
The Pathology of Severe COVID-19-Related Lung Damage.
BACKGROUND: The histomorphological changes of lung damage in severe coronavirus disease 2019 (COVID-19) have not yet been adequately characterized. In this article, we describe the sequence of pathological changes in COVID-19 and discuss the implications for approaches to treatment. METHODS: Standardized autopsies were...
Journal Article
Kommoss, Felix K F;Schwab, Constantin;Tavernar, Luca;Schreck, Johannes;Wagner, Willi L;Merle, Uta;Jonigk, Danny;Schirmacher, Peter;Longerich, Thomas
10.3238/arztebl.2020.0500
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: The Pathology of Severe COVID-19-Related Lung Damage. [Abstract]: BACKGROUND: The histomorphological changes of lung damage in severe coronavirus disease 2019 (COVID-19) have not yet been adequately characterized. In this article, we describe the sequence of pathological changes in COVID-19 and discuss the imp...
32,726,234
West J Emerg Med
Electronic Health Record-Based Surveillance for Community Transmitted COVID-19 in the Emergency Department.
INTRODUCTION: SARS-CoV-2, a novel coronavirus, manifests as a respiratory syndrome (COVID-19) and is the cause of an ongoing pandemic. The response to COVID-19 in the United States has been hampered by an overall lack of diagnostic testing capacity. To address uncertainty about ongoing levels of SARS-CoV-2 community tr...
Journal Article
Pulia, Michael S;Hekman, Daniel J;Glazer, Joshua M;Barclay-Buchanan, Ciara;Kuehnel, Nicholas;Ross, Joshua;Sharp, Brian;Batt, Robert;Patterson, Brian W
10.5811/westjem.2020.5.47606
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Electronic Health Record-Based Surveillance for Community Transmitted COVID-19 in the Emergency Department. [Abstract]: INTRODUCTION: SARS-CoV-2, a novel coronavirus, manifests as a respiratory syndrome (COVID-19) and is the cause of an ongoing pandemic. The response to COVID-19 in the United States has been h...
32,994,372
Hong Kong Med J
Clinical manifestations and outcomes of COVID-19 in the paediatric population: a systematic review.
OBJECTIVE: Coronavirus disease 2019 (COVID-19), the respiratory illness caused by severe acute respiratory syndrome coronavirus 2, has affected hundreds of thousands of people. We aim to report the distribution of cases, prevalence, and clinical, radiological, and laboratory signs and outcomes of COVID-19 in paediatric...
child;coronavirus;infant, newborn
Journal Article;Systematic Review
Jahangir, M;Nawaz, M;Nanjiani, D;Siddiqui, M S
10.12809/hkmj208646
[ 0, 1, 0, 0, 1, 0, 0 ]
[Title]: Clinical manifestations and outcomes of COVID-19 in the paediatric population: a systematic review. [Abstract]: OBJECTIVE: Coronavirus disease 2019 (COVID-19), the respiratory illness caused by severe acute respiratory syndrome coronavirus 2, has affected hundreds of thousands of people. We aim to report the d...
32,733,985
Arch Bone Jt Surg
Novel Coronavirus Infection in Orthopedic Patients ; Report of Seven Cases.
During the course of novel coronavirus pandemic ,Shariati hospital in Tehran , as a tertiary center in both orthopedic trauma and COVID-19 , we detected 7 cases with definite diagnosis of COVID-19 and concomitant emergent orthopedic problem.This paper represents considerations and special issues in managing and decisio...
coronavirus;fracture;orthopedic trauma
Case Reports
Rabie, Hamid;Sharafi, Mohammad Hasan;Oryadi Zanjani, Leila;Nabian, Mohammad Hossein
10.22038/abjs.2020.47805.2357
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Novel Coronavirus Infection in Orthopedic Patients ; Report of Seven Cases. [Abstract]: During the course of novel coronavirus pandemic ,Shariati hospital in Tehran , as a tertiary center in both orthopedic trauma and COVID-19 , we detected 7 cases with definite diagnosis of COVID-19 and concomitant emergent o...
32,102,625
Emerg Microbes Infect
Detectable 2019-nCoV viral RNA in blood is a strong indicator for the further clinical severity.
The novel coronavirus (2019-nCoV) infection caused pneumonia. we retrospectively analyzed the virus presence in the pharyngeal swab, blood, and the anal swab detected by real-time PCR in the clinical lab. Unexpectedly, the 2109-nCoV RNA was readily detected in the blood (6 of 57 patients) and the anal swabs (11 of 28 p...
2019-ncov;anal swab;blood viral rna;laboratory test;pharyngeal swab
Letter
Chen, Weilie;Lan, Yun;Yuan, Xiaozhen;Deng, Xilong;Li, Yueping;Cai, Xiaoli;Li, Liya;He, Ruiying;Tan, Yizhou;Deng, Xizi;Gao, Ming;Tang, Guofang;Zhao, Lingzhai;Wang, Jinlin;Fan, Qinghong;Wen, Chunyan;Tong, Yuwei;Tang, Yangbo;Hu, Fengyu;Li, Feng;Tang, Xiaoping
10.1080/22221751.2020.1732837
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Detectable 2019-nCoV viral RNA in blood is a strong indicator for the further clinical severity. [Abstract]: The novel coronavirus (2019-nCoV) infection caused pneumonia. we retrospectively analyzed the virus presence in the pharyngeal swab, blood, and the anal swab detected by real-time PCR in the clinical la...
32,629,788
Microorganisms
Calcineurin Inhibitor-Based Immunosuppression and COVID-19: Results from a Multidisciplinary Cohort of Patients in Northern Italy.
The role of immunosuppression in SARS-CoV-2-related disease (COVID-19) is a matter of debate. We here describe the course and the outcome of COVID-19 in a cohort of patients undergoing treatment with calcineurin inhibitors. In this monocentric cohort study, data were collected from the COVID-19 outbreak in Italy up to ...
covid-19;calcineurin inhibitors;rheumatic diseases;solid organ transplantation
Journal Article
Cavagna, Lorenzo;Seminari, Elena;Zanframundo, Giovanni;Gregorini, Marilena;Di Matteo, Angela;Rampino, Teresa;Montecucco, Carlomaurizio;Pelenghi, Stefano;Cattadori, Barbara;Pattonieri, Eleonora Francesca;Vitulo, Patrizio;Bertani, Alessandro;Sambataro, Gianluca;Vancheri, Carlo;Biglia, Alessandro;Bozzalla-Cassione, Emanue...
10.3390/microorganisms8070977
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Calcineurin Inhibitor-Based Immunosuppression and COVID-19: Results from a Multidisciplinary Cohort of Patients in Northern Italy. [Abstract]: The role of immunosuppression in SARS-CoV-2-related disease (COVID-19) is a matter of debate. We here describe the course and the outcome of COVID-19 in a cohort of pat...
32,511,784
Allergy
Diagnosis and management of the drug hypersensitivity reactions in Coronavirus disease 19: An EAACI Position Paper.
Coronavirus disease 2019 (COVID-19), a respiratory tract infection caused by a novel human coronavirus, the severe acute respiratory syndrome coronavirus 2, leads to a wide spectrum of clinical manifestations ranging from asymptomatic cases to patients with mild and severe symptoms, with or without pneumonia. Given the...
covid-19;sars-cov-2;desensitization;drug hypersensitivity reactions
Journal Article;Practice Guideline
Gelincik, Asli;Brockow, Knut;Celik, Gulfem E;Dona, Inmaculada;Mayorga, Cristobalina;Romano, Antonino;Soyer, Ozge;Atanaskovic-Markovic, Marina;Barbaud, Annick;Torres, Maria Jose
10.1111/all.14439
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Diagnosis and management of the drug hypersensitivity reactions in Coronavirus disease 19: An EAACI Position Paper. [Abstract]: Coronavirus disease 2019 (COVID-19), a respiratory tract infection caused by a novel human coronavirus, the severe acute respiratory syndrome coronavirus 2, leads to a wide spectrum o...
32,671,432
Int Orthop
COVID-19 pandemic: management of patients affected by SARS-CoV-2 in Rome COVID Hospital 2 Trauma Centre and safety of our surgical team.
BACKGROUND: SARS-CoV-2 pandemic left a deep mark in the health systems around the globe, leading to an important change in the way we intend the access to the healthcare and its fruition. Hospitals faced something unexpected, and they underwent a deep change and so did orthopaedic activity. MATERIALS AND METHODS: In "A...
covid-19;fractures;pandemic;trauma
Journal Article
De Mauro, Domenico;Rovere, Giuseppe;Smimmo, Alessandro;Meschini, Cesare;Mocini, Fabrizio;Maccauro, Giulio;Falez, Francesco;Liuzza, Francesco;Ziranu, Antonio
10.1007/s00264-020-04715-6
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 pandemic: management of patients affected by SARS-CoV-2 in Rome COVID Hospital 2 Trauma Centre and safety of our surgical team. [Abstract]: BACKGROUND: SARS-CoV-2 pandemic left a deep mark in the health systems around the globe, leading to an important change in the way we intend the access to the hea...
32,707,307
Water Res
Making waves: Wastewater surveillance of SARS-CoV-2 for population-based health management.
Worldwide, clinical data remain the gold standard for disease surveillance and tracking. However, such data are limited due to factors such as reporting bias and inability to track asymptomatic disease carriers. Disease agents are excreted in the urine and feces of infected individuals regardless of disease symptom sev...
data privacy;fecal-oral transmission;health management;sars-cov-2;wastewater surveillance
Journal Article
Thompson, Janelle R;Nancharaiah, Yarlagadda V;Gu, Xiaoqiong;Lee, Wei Lin;Rajal, Veronica B;Haines, Monamie B;Girones, Rosina;Ng, Lee Ching;Alm, Eric J;Wuertz, Stefan
10.1016/j.watres.2020.116181
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Making waves: Wastewater surveillance of SARS-CoV-2 for population-based health management. [Abstract]: Worldwide, clinical data remain the gold standard for disease surveillance and tracking. However, such data are limited due to factors such as reporting bias and inability to track asymptomatic disease carri...
32,485,618
J Clin Virol
Low performance of rapid antigen detection test as frontline testing for COVID-19 diagnosis.
BACKGROUND: Ensuring accurate diagnosis is essential to limit the spread of SARS-CoV-2 and for the clinical management of COVID-19. Although real-time reverse transcription polymerase chain reaction (RT- qPCR) is the current recommended laboratory method to diagnose SARS-CoV-2 acute infection, several factors such as r...
covid-19;rapid antigen detection test;sars-cov-2
Journal Article
Scohy, Anais;Anantharajah, Ahalieyah;Bodeus, Monique;Kabamba-Mukadi, Benoit;Verroken, Alexia;Rodriguez-Villalobos, Hector
10.1016/j.jcv.2020.104455
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Low performance of rapid antigen detection test as frontline testing for COVID-19 diagnosis. [Abstract]: BACKGROUND: Ensuring accurate diagnosis is essential to limit the spread of SARS-CoV-2 and for the clinical management of COVID-19. Although real-time reverse transcription polymerase chain reaction (RT- qP...
32,335,408
Sci Total Environ
Environmental perspective of COVID-19.
The outbreak of COVID-19 has caused concerns globally. On 30 January WHO has declared it as a global health emergency. The easy spread of this virus made people to wear a mask as precautionary route, use gloves and hand sanitizer on a daily basis that resulted in generation of a massive amount of medical wastes in the ...
covid-19;environment;pandemic;regulations;socioeconomic
Journal Article;Review
Saadat, Saeida;Rawtani, Deepak;Hussain, Chaudhery Mustansar
10.1016/j.scitotenv.2020.138870
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Environmental perspective of COVID-19. [Abstract]: The outbreak of COVID-19 has caused concerns globally. On 30 January WHO has declared it as a global health emergency. The easy spread of this virus made people to wear a mask as precautionary route, use gloves and hand sanitizer on a daily basis that resulted...
32,549,072
Int Braz J Urol
Special strategies and management of urological diseases during the COVID-19 pandemic: initial experiences from a Medical Center of China.
Although urological diseases are not directly related to coronavirus disease 2019 (COVID-19), urologists need to make comprehensive plans for this disease. Urological conditions such as benign prostatic hyperplasia and tumors are very common in elderly patients. This group of patients is often accompanied by underlying...
covid-19 [supplementary concept];pandemics;urology
Journal Article;Review
Chen, Wei;Wang, Xiao-Meng;Fu, Guang-Qing;Fu, Guang-Qing;Zeng, Xiang;Wu, Cui-Ping;Liang, Yong;Liu, Jian-Hui;Teoh, Jeremy Yuen-Chun
10.1590/S1677-5538.IBJU.2020.S102
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Special strategies and management of urological diseases during the COVID-19 pandemic: initial experiences from a Medical Center of China. [Abstract]: Although urological diseases are not directly related to coronavirus disease 2019 (COVID-19), urologists need to make comprehensive plans for this disease. Urol...
32,395,418
Curr Pharmacol Rep
An Update on Current Therapeutic Drugs Treating COVID-19.
The current pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has presented unprecedented challenges to the healthcare systems in almost every country around the world. Currently, there are no proven effective vaccines or therapeutic agents against th...
anakinra;azithromycin;covid-19;chloroquine;convalescent plasma;epoprostenol;favipiravir;hydroxychloroquine;lopinavir;methylprednisolone;nitric oxide;oseltamivir;remdesivir;sar-cov-2;sarilumab;sirolimus;tocilizumab;traditional chinese medicine;umifenovir;vitamin c
Journal Article;Review
Wu, Renyi;Wang, Lujing;Kuo, Hsiao-Chen Dina;Shannar, Ahmad;Peter, Rebecca;Chou, Pochung Jordan;Li, Shanyi;Hudlikar, Rasika;Liu, Xia;Liu, Zhigang;Poiani, George J;Amorosa, Louis;Brunetti, Luigi;Kong, Ah-Ng
10.1007/s40495-020-00216-7
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: An Update on Current Therapeutic Drugs Treating COVID-19. [Abstract]: The current pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has presented unprecedented challenges to the healthcare systems in almost every country around the world. Cur...
32,978,341
WHO South East Asia J Public Health
Community action for people with HIV and sex workers during the COVID-19 pandemic in India.
Sex workers have been one of the marginalized groups that have been particularly affected by India's stringent lockdown in response to the coronavirus disease 2019 (COVID-19) pandemic. The sudden loss of livelihood and lack of access to health care and social protection intensified the vulnerabilities of sex workers, e...
india;antiretroviral therapy;community;emergency response;sex workers
Journal Article
Reza-Paul, Sushena;Lazarus, Lisa;Haldar, Partha;Reza Paul, Manisha;Lakshmi, Bhagya;Ramaiah, Manjula;Pasha, Akram;Hafeez Ur Rahman, Syed;Venukumar, K T;Venugopa, M S;Rewari, Bharat Bhushan;Lorway, Robert
10.4103/2224-3151.294302
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Community action for people with HIV and sex workers during the COVID-19 pandemic in India. [Abstract]: Sex workers have been one of the marginalized groups that have been particularly affected by India's stringent lockdown in response to the coronavirus disease 2019 (COVID-19) pandemic. The sudden loss of liv...
32,719,214
Indian J Med Microbiol
Comparative analysis of clinical characteristics, imaging and laboratory findings of different age groups with COVID-19.
Objective: This study aims to provide scientific basis for rapid screening and early diagnosis of the coronavirus disease 2019 (COVID-19) through analysing the clinical characteristics and early imaging/laboratory findings of the inpatients. Methods: Three hundred and three patients with laboratory-confirmed COVID-19 f...
age;clinical characteristics;coronavirus disease 2019;imaging;laboratory investigations
Journal Article
Liu, Xuemei;Lv, Jie;Gan, Lin;Zhang, Ying;Sun, Feng;Meng, Bo;Jheon, Andrew;Yan, Fang;Li, Bin;Xuan, Zhou;Ma, Xiumin;Wulasihana, Muhuyati
10.4103/ijmm.IJMM_20_133
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Comparative analysis of clinical characteristics, imaging and laboratory findings of different age groups with COVID-19. [Abstract]: Objective: This study aims to provide scientific basis for rapid screening and early diagnosis of the coronavirus disease 2019 (COVID-19) through analysing the clinical character...
32,574,268
Front Immunol
Fighting the Host Reaction to SARS-COv-2 in Critically Ill Patients: The Possible Contribution of Off-Label Drugs.
The severe acute respiratory syndrome coronavirus 2 (SARS-COv-2) is the etiologic agent of the 2019 coronavirus disease (COVID19). The majority of infected people presents flu like symptoms and among them 15-20% develops a severe interstitial pneumonitis (IP) that may eventually evolve in acute respiratory distress syn...
cytokine;inflammation;interstitial pneumonia;macrophages;offlabel drug use
Journal Article;Review
Scala, Stefania;Pacelli, Roberto
10.3389/fimmu.2020.01201
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Fighting the Host Reaction to SARS-COv-2 in Critically Ill Patients: The Possible Contribution of Off-Label Drugs. [Abstract]: The severe acute respiratory syndrome coronavirus 2 (SARS-COv-2) is the etiologic agent of the 2019 coronavirus disease (COVID19). The majority of infected people presents flu like sym...
32,789,663
Infect Dis Ther
Interleukin-6 Blocking vs. JAK-STAT Inhibition for Prevention of Lung Injury in Patients with COVID-19.
The severe respiratory insufficiency observed during COVID-19 infection may not be directly related to a cytopathogenic effect induced by the virus itself, but to an exaggerated and inappropriate immune response. In an effort to reduce the severity of organ dysfunction, including respiratory insufficiency, monoclonal a...
covid-19;cytokine storm;il6 blocking;jak-stat inhibitors;ruxolitinib;sarilumab;severe respiratory syndrome;siltuximab;tocilizumab
Journal Article
Meletiadis, Joseph;Tsiodras, Sotirios;Tsirigotis, Panagiotis
10.1007/s40121-020-00326-1
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Interleukin-6 Blocking vs. JAK-STAT Inhibition for Prevention of Lung Injury in Patients with COVID-19. [Abstract]: The severe respiratory insufficiency observed during COVID-19 infection may not be directly related to a cytopathogenic effect induced by the virus itself, but to an exaggerated and inappropriate...
32,584,798
MMWR Morb Mortal Wkly Rep
Progress Toward Polio Eradication - Worldwide, January 2018-March 2020.
Since the Global Polio Eradication Initiative (GPEI) was established in 1988, two of the three wild poliovirus (WPV) serotypes (types 2 and 3) have been eradicated.* Transmission of WPV type 1 (WPV1) remains uninterrupted only in Afghanistan and Pakistan. This report summarizes progress toward global polio eradication ...
Journal Article
Chard, Anna N;Datta, S Deblina;Tallis, Graham;Burns, Cara C;Wassilak, Steven G F;Vertefeuille, John F;Zaffran, Michel
10.15585/mmwr.mm6925a4
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Progress Toward Polio Eradication - Worldwide, January 2018-March 2020. [Abstract]: Since the Global Polio Eradication Initiative (GPEI) was established in 1988, two of the three wild poliovirus (WPV) serotypes (types 2 and 3) have been eradicated.* Transmission of WPV type 1 (WPV1) remains uninterrupted only ...
32,854,262
Nutrients
The Antiviral, Anti-Inflammatory Effects of Natural Medicinal Herbs and Mushrooms and SARS-CoV-2 Infection.
The 2019 novel coronavirus, SARS-CoV-2, producing the disease COVID-19 is a pathogenic virus that targets mostly the human respiratory system and also other organs. SARS-CoV-2 is a new strain that has not been previously identified in humans, however there have been previous outbreaks of different versions of the beta ...
covid-19;sars-cov-2;antiviral;coronavirus;herbs;mushrooms
Journal Article;Review
Shahzad, Fanila;Anderson, Diana;Najafzadeh, Mojgan
10.3390/nu12092573
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: The Antiviral, Anti-Inflammatory Effects of Natural Medicinal Herbs and Mushrooms and SARS-CoV-2 Infection. [Abstract]: The 2019 novel coronavirus, SARS-CoV-2, producing the disease COVID-19 is a pathogenic virus that targets mostly the human respiratory system and also other organs. SARS-CoV-2 is a new strain...
32,796,119
Thorax
Clinical and laboratory evaluation of SARS-CoV-2 lateral flow assays for use in a national COVID-19 seroprevalence survey.
BACKGROUND: Accurate antibody tests are essential to monitor the SARS-CoV-2 pandemic. Lateral flow immunoassays (LFIAs) can deliver testing at scale. However, reported performance varies, and sensitivity analyses have generally been conducted on serum from hospitalised patients. For use in community testing, evaluation...
clinical epidemiology;respiratory infection;viral infection
Journal Article;Research Support, Non-U.S. Gov't
Flower, Barnaby;Brown, Jonathan C;Simmons, Bryony;Moshe, Maya;Frise, Rebecca;Penn, Rebecca;Kugathasan, Ruthiran;Petersen, Claire;Daunt, Anna;Ashby, Deborah;Riley, Steven;Atchison, Christina Joanne;Taylor, Graham P;Satkunarajah, Sutha;Naar, Lenny;Klaber, Robert;Badhan, Anjna;Rosadas, Carolina;Khan, Maryam;Fernandez, Nat...
10.1136/thoraxjnl-2020-215732
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical and laboratory evaluation of SARS-CoV-2 lateral flow assays for use in a national COVID-19 seroprevalence survey. [Abstract]: BACKGROUND: Accurate antibody tests are essential to monitor the SARS-CoV-2 pandemic. Lateral flow immunoassays (LFIAs) can deliver testing at scale. However, reported performa...
33,027,239
Pediatr Crit Care Med
A Hybrid Model of Pediatric and Adult Critical Care During the Coronavirus Disease 2019 Surge: The Experience of Two Tertiary Hospitals in London and New York.
OBJECTIVES: The current novel severe acute respiratory syndrome coronavirus 2 outbreak has caused an unprecedented demand on global adult critical care services. As adult patients have been disproportionately affected by the coronavirus disease 2019 pandemic, pediatric practitioners world-wide have stepped forward to s...
Journal Article
Deep, Akash;Knight, Philip;Kernie, Steven G;D'Silva, Pam;Sobin, Brittany;Best, Thomas;Zorrilla, Maria;Carson, Lydia;Zoica, Bogdana;Ahn, Danielle
10.1097/PCC.0000000000002584
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: A Hybrid Model of Pediatric and Adult Critical Care During the Coronavirus Disease 2019 Surge: The Experience of Two Tertiary Hospitals in London and New York. [Abstract]: OBJECTIVES: The current novel severe acute respiratory syndrome coronavirus 2 outbreak has caused an unprecedented demand on global adult c...
32,726,245
West J Emerg Med
Telehealth Solutions for In-hospital Communication with Patients Under Isolation During COVID-19.
The coronavirus disease 2019 (COVID-19) pandemic is a public health crisis that has quickly overwhelmed our healthcare system. It has led to significant shortages in personal protective equipment (PPE), ventilators, and intensive care unit beds across the nation. As the initial entry point for patients with suspected C...
Journal Article
Fang, Jennifer;Liu, Yiju T;Lee, Ernest Y;Yadav, Kabir
10.5811/westjem.2020.5.48165
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Telehealth Solutions for In-hospital Communication with Patients Under Isolation During COVID-19. [Abstract]: The coronavirus disease 2019 (COVID-19) pandemic is a public health crisis that has quickly overwhelmed our healthcare system. It has led to significant shortages in personal protective equipment (PPE)...
32,834,579
Chaos Solitons Fractals
Modeling COVID-19 epidemic in Heilongjiang province, China.
The Coronavirus Disease 2019 (COVID-19) surges worldwide. However, massive imported patients especially into Heilongjiang Province in China recently have been an alert for local COVID-19 outbreak. We collected data from January 23 to March 25 from Heilongjiang province and trained an ordinary differential equation mode...
asymptomatic patient;covid-19;epidemic;imported patient
Journal Article
Sun, Tingzhe;Wang, Yan
10.1016/j.chaos.2020.109949
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: Modeling COVID-19 epidemic in Heilongjiang province, China. [Abstract]: The Coronavirus Disease 2019 (COVID-19) surges worldwide. However, massive imported patients especially into Heilongjiang Province in China recently have been an alert for local COVID-19 outbreak. We collected data from January 23 to March...
32,630,514
Pharmaceuticals (Basel)
Preliminary Virtual Screening Studies to Identify GRP78 Inhibitors Which May Interfere with SARS-CoV-2 Infection.
SARS-CoV-2 Spike protein was predicted by molecular docking to bind the host cell surface GRP78, which was suggested as a putative good molecular target to inhibit Covid-19. We aimed to confirm that GRP78 gene expression was increased in blood of SARS-CoV-2 (+) versus SARS-CoV-2 (-) pneumonia patients. In addition, we ...
covid-19;grp78;sars-cov-2;antiviral;gene expression;repurposed drugs;virtual screening
Journal Article
Palmeira, Andreia;Sousa, Emilia;Koseler, Aylin;Sabirli, Ramazan;Goren, Tarik;Turkcuer, Ibrahim;Kurt, Ozgur;Pinto, Madalena M;Vasconcelos, M Helena
10.3390/ph13060132
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Preliminary Virtual Screening Studies to Identify GRP78 Inhibitors Which May Interfere with SARS-CoV-2 Infection. [Abstract]: SARS-CoV-2 Spike protein was predicted by molecular docking to bind the host cell surface GRP78, which was suggested as a putative good molecular target to inhibit Covid-19. We aimed to...
33,029,476
IDCases
The first case of documented Covid-19 reinfection in Israel.
We describe the first documented case of Covid-19 reinfection in Israel, out of only a handful such case worldwide, in a 20year old otherwise healthy young woman. In the first occasion she was mildly symptomatic, whereas the second episode was apparently asymptomatic, except for tachycardia of 90/min, compared to 60/mi...
antibodies;covid 19;immunity;israel;reinfection
Case Reports
Nachmias, Vered;Fusman, Renato;Mann, Suzy;Koren, Gideon
10.1016/j.idcr.2020.e00970
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: The first case of documented Covid-19 reinfection in Israel. [Abstract]: We describe the first documented case of Covid-19 reinfection in Israel, out of only a handful such case worldwide, in a 20year old otherwise healthy young woman. In the first occasion she was mildly symptomatic, whereas the second episod...
32,837,224
J Neonatal Nurs
COVID-19 in babies: Knowledge for neonatal care.
Infection is a leading cause of death worldwide in babies under one month of age who are more susceptible to sepsis due to immature host defence mechanisms. Usually, babies may become acutely unwell from infective pathogens due to specific differences in their respiratory and immune systems. However, with the COVID-19 ...
covid-19;care implications;neonate;pathophysiology;transmission
Journal Article;Review
Green, Janet;Petty, Julia;Bromley, Patricia;Walker, Karen;Jones, Linda
10.1016/j.jnn.2020.06.005
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 in babies: Knowledge for neonatal care. [Abstract]: Infection is a leading cause of death worldwide in babies under one month of age who are more susceptible to sepsis due to immature host defence mechanisms. Usually, babies may become acutely unwell from infective pathogens due to specific difference...
32,766,267
Front Med (Lausanne)
Extensive Testing May Reduce COVID-19 Mortality: A Lesson From Northern Italy.
The effects of different COVID-19 swab testing policies in Italy need investigation. We examined the relationship between the number of COVID-19 swab tests (per 10,000 population) performed from February 24 through March 27 and 7-day lagged COVID-19 mortality (per 10,000 population) in four regions of northern Italy. L...
covid-19;echologic studies;epidemics;mortality;surveillance;swab testing
Journal Article
Di Bari, Mauro;Balzi, Daniela;Carreras, Giulia;Onder, Graziano
10.3389/fmed.2020.00402
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Extensive Testing May Reduce COVID-19 Mortality: A Lesson From Northern Italy. [Abstract]: The effects of different COVID-19 swab testing policies in Italy need investigation. We examined the relationship between the number of COVID-19 swab tests (per 10,000 population) performed from February 24 through March...
32,653,961
Emerg Radiol
Radiographic and chest CT imaging presentation and follow-up of COVID-19 pneumonia: a multicenter experience from an endemic area.
COVID-19 has infected more than 2 million people in the world in less than 5 months outbreak. Chest imaging is recommended for triage of suspected cases of COVID-19 with moderate-severe clinical features and high pre-test probability of disease, and may help for patient follow-up and to identify patients at higher risk...
ct;coronavirus disease 2019 (covid-19);coronavirus infections;pulmonary embolism;sars-cov-2
Journal Article;Multicenter Study
Vernuccio, Federica;Giambelluca, Dario;Cannella, Roberto;Lombardo, Francesco Paolo;Panzuto, Fabio;Midiri, Massimo;Cabassa, Paolo
10.1007/s10140-020-01817-x
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Radiographic and chest CT imaging presentation and follow-up of COVID-19 pneumonia: a multicenter experience from an endemic area. [Abstract]: COVID-19 has infected more than 2 million people in the world in less than 5 months outbreak. Chest imaging is recommended for triage of suspected cases of COVID-19 wit...
33,026,573
Hepatol Int
Clinical characteristics and risk factors of liver injury in COVID-19: a retrospective cohort study from Wuhan, China.
BACKGROUND: Coronavirus disease 2019 (COVID-19) has rapidly become a major international public health concern. This study was designed to evaluate the clinical characteristics and risk factors of COVID-19-associated liver injury. METHODS: A fraction of 657 COVID-19 patients were retrospectively analyzed. Clinical and ...
alanine aminotransferase;covid-19;clinical course;cytokine storm;hypersensitive c-reactive protein;liver damage;multivariate regression analysis;neutrophil-to-lymphocyte ratio;retrospective cohort study;total bilirubin
Journal Article
Wang, Ming;Yan, Weiming;Qi, Weipeng;Wu, Di;Zhu, Lin;Li, Weina;Wang, Xiaojing;Ma, Ke;Ni, Ming;Xu, Dong;Wang, Hongwu;Chen, Guang;Yu, Haijing;Ding, Hongfang;Xing, Mingyou;Han, Meifang;Luo, Xiaoping;Chen, Tao;Guo, Wei;Xi, Dong;Ning, Qin
10.1007/s12072-020-10075-5
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical characteristics and risk factors of liver injury in COVID-19: a retrospective cohort study from Wuhan, China. [Abstract]: BACKGROUND: Coronavirus disease 2019 (COVID-19) has rapidly become a major international public health concern. This study was designed to evaluate the clinical characteristics and...
32,565,900
Ecancermedicalscience
Cancer is associated with severe disease in COVID-19 patients: a systematic review and meta-analysis.
Cancer patients are vulnerable to complications of respiratory viruses. This systematic review and meta-analysis sought to examine the prevalence of cancer and its association with disease severity in patients with novel coronavirus disease 2019 (COVID-19). Searches were performed in MEDLINE, EMBASE and ScienceDirect f...
covid-19;sars;coronavirus;pandemic
Journal Article
Ofori-Asenso, Richard;Ogundipe, Oyepeju;Agyeman, Akosua Adom;Chin, Ken Lee;Mazidi, Mohsen;Ademi, Zanfina;De Bruin, Marie Louise;Liew, Danny
10.3332/ecancer.2020.1047
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Cancer is associated with severe disease in COVID-19 patients: a systematic review and meta-analysis. [Abstract]: Cancer patients are vulnerable to complications of respiratory viruses. This systematic review and meta-analysis sought to examine the prevalence of cancer and its association with disease severity...
32,861,887
Heart Lung
Surviving 2019 novel coronavirus pneumonia: A successful critical case report.
BACKGROUND: . An outbreak of acute respiratory illness was proved to be infected by a novel coronavirus, officially named Coronavirus Disease 2019 (COVID-19) from World Health Organization (WHO), was confirmed first in Wuhan, China, and has become endemic worldwide, which was a serious threaten to public health all ove...
acp;ards;covid-19;prone position ventilation
Case Reports;Journal Article
Zou, Lei;Sun, Jiakui;Liu, Ying;Zhang, Wenhao;Jiang, Wei;Yuan, Shoutao;Shi, Qiankun
10.1016/j.hrtlng.2020.08.009
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Surviving 2019 novel coronavirus pneumonia: A successful critical case report. [Abstract]: BACKGROUND: . An outbreak of acute respiratory illness was proved to be infected by a novel coronavirus, officially named Coronavirus Disease 2019 (COVID-19) from World Health Organization (WHO), was confirmed first in W...
32,669,150
Infect Control Hosp Epidemiol
The utility of chest computed tomography (CT) and RT-PCR screening of asymptomatic patients for SARS-CoV-2 prior to semiurgent or urgent hospital procedures.
OBJECTIVE: Presently, evidence guiding clinicians on the optimal approach to safely screen patients for coronavirus disease 2019 (COVID-19) to a nonemergent hospital procedure is scarce. In this report, we describe our experience in screening for SARS-CoV-2 prior to semiurgent and urgent hospital procedures. DESIGN: Re...
Journal Article
Shah, Aditya S;Walkoff, Lara A;Kuzo, Ronald S;Callstrom, Matthew R;Brown, Michael J;Kendrick, Michael L;Narr, Bradly J;Berbari, Elie
10.1017/ice.2020.331
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: The utility of chest computed tomography (CT) and RT-PCR screening of asymptomatic patients for SARS-CoV-2 prior to semiurgent or urgent hospital procedures. [Abstract]: OBJECTIVE: Presently, evidence guiding clinicians on the optimal approach to safely screen patients for coronavirus disease 2019 (COVID-19) t...