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32,721,804
Med Hypotheses
Recombinant protein targeting and opsonizing spike glycoprotein for enhancing SARS-CoV-2 phagocytosis.
The present hypothesis suggests an innovative therapeutic strategy to cease Covid 19 infection. It is based on the inhibition of Spike glycoprotein and ACE-2 receptor interaction that provides the entry of virus in human host cells, by targeting the S protein with a recombinant molecule made of the ACE-2 receptor ectod...
ace-2 ectodomain;opsonin;phagocytosis;recombinant;sars-cov-2;spike
Letter
Khattabi, Latifa
10.1016/j.mehy.2020.110108
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Recombinant protein targeting and opsonizing spike glycoprotein for enhancing SARS-CoV-2 phagocytosis. [Abstract]: The present hypothesis suggests an innovative therapeutic strategy to cease Covid 19 infection. It is based on the inhibition of Spike glycoprotein and ACE-2 receptor interaction that provides the...
32,856,766
FASEB J
Clinical sensitivity and interpretation of PCR and serological COVID-19 diagnostics for patients presenting to the hospital.
The diagnosis of COVID-19 requires integration of clinical and laboratory data. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diagnostic assays play a central role in diagnosis and have fixed technical performance metrics. Interpretation becomes challenging because the clinical sensitivity changes as the...
covid;sars-cov-2;biomarker;qpcr
Clinical Trial;Journal Article;Research Support, N.I.H., Extramural;Research Support, U.S. Gov't, P.H.S.
Miller, Tyler E;Garcia Beltran, Wilfredo F;Bard, Adam Z;Gogakos, Tasos;Anahtar, Melis N;Astudillo, Michael Gerino;Yang, Diane;Thierauf, Julia;Fisch, Adam S;Mahowald, Grace K;Fitzpatrick, Megan J;Nardi, Valentina;Feldman, Jared;Hauser, Blake M;Caradonna, Timothy M;Marble, Hetal D;Ritterhouse, Lauren L;Turbett, Sara E;Ba...
10.1096/fj.202001700RR
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical sensitivity and interpretation of PCR and serological COVID-19 diagnostics for patients presenting to the hospital. [Abstract]: The diagnosis of COVID-19 requires integration of clinical and laboratory data. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diagnostic assays play a central ...
32,283,139
J Infect
Household transmission of SARS-CoV-2.
BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused an epidemic in China and many other countries. Many infected clusters have been found within familial households, but the data about secondary transmission among household contacts is limited. METHODS: In this retrospective case series,...
household;sars-cov-2;transmission;wuhan
Journal Article
Wang, Zhongliang;Ma, Wanli;Zheng, Xin;Wu, Gang;Zhang, Ruiguang
10.1016/j.jinf.2020.03.040
[ 0, 0, 0, 0, 1, 0, 0 ]
[Title]: Household transmission of SARS-CoV-2. [Abstract]: BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused an epidemic in China and many other countries. Many infected clusters have been found within familial households, but the data about secondary transmission among household conta...
32,897,764
J Urol
Androgen Deprivation Therapy in Men with Prostate Cancer Does Not Affect Risk of Infection with SARS-CoV-2.
PURPOSE: TMPRSS2 is a host co-receptor for cell entry of SARS-CoV-2. A prior report suggested that use of androgen deprivation therapy, which downregulates TMPRSS2, may protect men with prostate cancer from infection. MATERIALS AND METHODS: This is a cohort study of a prospective registry of all patients tested for SAR...
covid-19;sars virus;androgens;prostatic neoplasms
Journal Article
Klein, Eric A;Li, Jianbo;Milinovich, Alex;Schold, Jesse D;Sharifi, Nima;Kattan, Michael W;Jehi, Lara
10.1097/JU.0000000000001338
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Androgen Deprivation Therapy in Men with Prostate Cancer Does Not Affect Risk of Infection with SARS-CoV-2. [Abstract]: PURPOSE: TMPRSS2 is a host co-receptor for cell entry of SARS-CoV-2. A prior report suggested that use of androgen deprivation therapy, which downregulates TMPRSS2, may protect men with prost...
32,871,242
Pulm Pharmacol Ther
Dual-histamine receptor blockade with cetirizine - famotidine reduces pulmonary symptoms in COVID-19 patients.
BACKGROUND: The COVID-19 pandemic due to SARS-CoV-2 infection can produce Acute Respiratory Distress Syndrome as a result of a pulmonary cytokine storm. Antihistamines are safe and effective treatments for reducing inflammation and cytokine release. Combinations of Histamine-1 and Histamine-2 receptor antagonists have ...
ards;antihistamine;covid;cytokine storm;histamine;lung
Journal Article
Hogan Ii, Reed B;Hogan Iii, Reed B;Cannon, Tim;Rappai, Maria;Studdard, John;Paul, Doug;Dooley, Thomas P
10.1016/j.pupt.2020.101942
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Dual-histamine receptor blockade with cetirizine - famotidine reduces pulmonary symptoms in COVID-19 patients. [Abstract]: BACKGROUND: The COVID-19 pandemic due to SARS-CoV-2 infection can produce Acute Respiratory Distress Syndrome as a result of a pulmonary cytokine storm. Antihistamines are safe and effecti...
32,576,501
J Infect Public Health
What if the worst consequences of COVID-19 concerned non-COVID patients?
We highlight in this short article the side-effects of COVID-19 pandemic on the management of non-COVID patients, with potential detrimental and irreversible complications. We thus propose adjusted strategies to deal with both COVID and non-COVID patients.
covid-19;pandemic;public health system
Journal Article
Goulabchand, Radjiv;Claret, Pierre-Geraud;Lattuca, Benoit
10.1016/j.jiph.2020.06.014
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: What if the worst consequences of COVID-19 concerned non-COVID patients? [Abstract]: We highlight in this short article the side-effects of COVID-19 pandemic on the management of non-COVID patients, with potential detrimental and irreversible complications. We thus propose adjusted strategies to deal with both...
32,857,808
PLoS One
SNPs or RNA modifications? Concerns on mutation-based evolutionary studies of SARS-CoV-2.
SARS-CoV-2 is still rampaging throughout the world while the many evolutionary studies on it are simultaneously springing up. Researchers have simply utilized the public RNA-seq data to find out the so-called SNPs in the virus genome. The evolutionary analyses were largely based on these mutations. Here, we claim that ...
Journal Article;Research Support, Non-U.S. Gov't
Li, Yue;Yang, Xinai;Wang, Na;Wang, Haiyan;Yin, Bin;Yang, Xiaoping;Jiang, Wenqing
10.1371/journal.pone.0238490
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: SNPs or RNA modifications? Concerns on mutation-based evolutionary studies of SARS-CoV-2. [Abstract]: SARS-CoV-2 is still rampaging throughout the world while the many evolutionary studies on it are simultaneously springing up. Researchers have simply utilized the public RNA-seq data to find out the so-called ...
32,726,230
West J Emerg Med
Remdesivir for the Treatment of COVID-19: A Systematic Review of the Literature.
In March 2020, the World Health Organization declared the spread of SARS-CoV-2 a global pandemic. To date, coronavirus disease-2019 (COVID-19) has spread to over 200 countries, leading to over 1.6 million cases and over 99,000 deaths. Given that there is neither a vaccine nor proven treatment for COVID-19, there is cur...
Journal Article;Systematic Review
Musa, Arif;Pendi, Kasim;Hashemi, Areio;Warbasse, Elizabeth;Kouyoumjian, Sarkis;Yousif, Jenna;Blodget, Emily;Stevens, Susan;Aly, Besma;Baron, David A
10.5811/westjem.2020.5.47658
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Remdesivir for the Treatment of COVID-19: A Systematic Review of the Literature. [Abstract]: In March 2020, the World Health Organization declared the spread of SARS-CoV-2 a global pandemic. To date, coronavirus disease-2019 (COVID-19) has spread to over 200 countries, leading to over 1.6 million cases and ove...
32,773,926
Med J Armed Forces India
Cardiovascular comorbidities and complications associated with coronavirus disease 2019.
Coronavirus disease 2019 (COVID-19) has caused a devastating global pandemic and continues to overwhelm the health-care facilities and shatter the economies of countries worldwide. Although it primarily affects the lungs, it shares a strong interplay with the cardiovascular system. The presence of underlying cardiovasc...
covid-19;cardiovascular disease;comorbidities;complications;coronavirus
Journal Article;Review
Mahajan, Kunal;Chandra, K Sarat
10.1016/j.mjafi.2020.05.004
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: Cardiovascular comorbidities and complications associated with coronavirus disease 2019. [Abstract]: Coronavirus disease 2019 (COVID-19) has caused a devastating global pandemic and continues to overwhelm the health-care facilities and shatter the economies of countries worldwide. Although it primarily affects...
32,910,919
Cell Host Microbe
Snatching the Crown from SARS-CoV-2.
In this issue of Cell Host & Microbe, three papers describe the pseudotyping of vesicular stomatitis virus (VSV) with the SARS-CoV-2 spike. This VSV-CoV-2-S platform allows virus neutralization assays to be performed at BSL-2 and also has applications as a candidate vectored vaccine to elicit protective immunity agains...
Journal Article;Comment
Coughlan, Lynda
10.1016/j.chom.2020.08.007
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Snatching the Crown from SARS-CoV-2. [Abstract]: In this issue of Cell Host & Microbe, three papers describe the pseudotyping of vesicular stomatitis virus (VSV) with the SARS-CoV-2 spike. This VSV-CoV-2-S platform allows virus neutralization assays to be performed at BSL-2 and also has applications as a candi...
33,045,476
Clin Imaging
Differential diagnosis between the coronavirus disease 2019 and Streptococcus pneumoniae pneumonia by thin-slice CT features.
OBJECTIVE: The chest computed tomography (CT) features of coronavirus disease 2019 (COVID-19) and Streptococcus pneumoniae pneumonia (S. pneumoniae pneumonia) were compared to provide further evidence for the differential imaging diagnosis of patients with these two types of pneumonia. METHODS: Clinical information and...
computed tomography;coronavirus disease 2019 (covid-19);differential diagnosis;streptococcus pneumoniae
Journal Article
Zhou, Jun;Liao, Xingnan;Cao, Jia;Ling, Gonghao;Ding, Xun;Long, QingYun
10.1016/j.clinimag.2020.09.012
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Differential diagnosis between the coronavirus disease 2019 and Streptococcus pneumoniae pneumonia by thin-slice CT features. [Abstract]: OBJECTIVE: The chest computed tomography (CT) features of coronavirus disease 2019 (COVID-19) and Streptococcus pneumoniae pneumonia (S. pneumoniae pneumonia) were compared ...
32,793,621
Front Med (Lausanne)
Emergency Response Measures for Anesthesia Nursing During the COVID-19 Pandemic: West China Hospital Experiences.
During the COVID-19 pandemic, ensuring the gradual recovery of anesthesia nursing unit and avoiding cross-infection between surgical patients and staff are difficult problems for hospital managers. We outlined the emergency response measures and the transition to normal operation of the anesthesia nursing unit in West ...
covid-19;anesthesia nursing;epidemic prevention;novel coronavirus pneumonia;nursing management
Journal Article
Zheng, Ping;Zhou, Ruihao;Yin, Lu;Yin, Xiaorong;Mao, Yongqiao;Wang, Heng;Ye, Ling;Zhu, Tao
10.3389/fmed.2020.00460
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Emergency Response Measures for Anesthesia Nursing During the COVID-19 Pandemic: West China Hospital Experiences. [Abstract]: During the COVID-19 pandemic, ensuring the gradual recovery of anesthesia nursing unit and avoiding cross-infection between surgical patients and staff are difficult problems for hospit...
32,397,011
Influenza Other Respir Viruses
Epidemiological, clinical, and virological characteristics of 465 hospitalized cases of coronavirus disease 2019 (COVID-19) from Zhejiang province in China.
BACKGROUND: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the associated coronavirus disease (COVID-19) have spread throughout China. Previous studies predominantly focused on its place of origin, Wuhan, causing over estimation of the disease severity due to selection bias. We analyzed 465 confir...
zhejiang province;coronavirus disease 2019 (covid-19);risk factors;severe acute respiratory syndrome coronavirus 2 (sars-cov-2)
Journal Article;Research Support, Non-U.S. Gov't
Lian, Jiangshan;Jin, Xi;Hao, Shaorui;Jia, Hongyu;Cai, Huan;Zhang, Xiaoli;Hu, Jianhua;Zheng, Lin;Wang, Xiaoyan;Zhang, Shanyan;Ye, Chanyuan;Jin, Ciliang;Yu, Guodong;Gu, Jueqing;Lu, Yingfeng;Yu, Xiaopeng;Xiang, Dairong;Li, Lanjuan;Liang, Tingbo;Sheng, Jifang;Yang, Yida
10.1111/irv.12758
[ 0, 1, 0, 1, 0, 0, 0 ]
[Title]: Epidemiological, clinical, and virological characteristics of 465 hospitalized cases of coronavirus disease 2019 (COVID-19) from Zhejiang province in China. [Abstract]: BACKGROUND: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the associated coronavirus disease (COVID-19) have spread thr...
32,546,635
J Neurointerv Surg
COVID-19 and neurointerventional service worldwide: a survey of the European Society of Minimally Invasive Neurological Therapy (ESMINT), the Society of NeuroInterventional Surgery (SNIS), the Sociedad Iberolatinoamericana de Neuroradiologia Diagnostica y Terapeutica (SILAN), the Society of Vascular and Interventional ...
BACKGROUND: This survey was focused on the provision of neurointerventional services, the current practices of managing patients under COVID-19 conditions, and the expectations for the future. METHODS: Invitations for this survey were sent out as a collaborative effort of the European Society of Minimally Invasive Neur...
intervention;political;standards;stroke;thrombectomy
Journal Article
Fiehler, Jens;Brouwer, Patrick;Diaz, Carlos;Hirsch, Joshua A;Kulcsar, Zsolt;Liebeskind, David;Linfante, Italo;Lylyk, Pedro;Mack, William J;Milburn, James;Nogueira, Raul;Orbach, Darren B;Pumar, Jose Manuel Manuel;Tanaka, Michihiro;Taylor, Allan
10.1136/neurintsurg-2020-016349
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 and neurointerventional service worldwide: a survey of the European Society of Minimally Invasive Neurological Therapy (ESMINT), the Society of NeuroInterventional Surgery (SNIS), the Sociedad Iberolatinoamericana de Neuroradiologia Diagnostica y Terapeutica (SILAN), the Society of Vascular and Interv...
32,514,174
Nat Med
A single-cell atlas of the peripheral immune response in patients with severe COVID-19.
There is an urgent need to better understand the pathophysiology of Coronavirus disease 2019 (COVID-19), the global pandemic caused by SARS-CoV-2, which has infected more than three million people worldwide(1). Approximately 20% of patients with COVID-19 develop severe disease and 5% of patients require intensive care(...
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't;Research Support, U.S. Gov't, Non-P.H.S.
Wilk, Aaron J;Rustagi, Arjun;Zhao, Nancy Q;Roque, Jonasel;Martinez-Colon, Giovanny J;McKechnie, Julia L;Ivison, Geoffrey T;Ranganath, Thanmayi;Vergara, Rosemary;Hollis, Taylor;Simpson, Laura J;Grant, Philip;Subramanian, Aruna;Rogers, Angela J;Blish, Catherine A
10.1038/s41591-020-0944-y
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: A single-cell atlas of the peripheral immune response in patients with severe COVID-19. [Abstract]: There is an urgent need to better understand the pathophysiology of Coronavirus disease 2019 (COVID-19), the global pandemic caused by SARS-CoV-2, which has infected more than three million people worldwide(1). ...
32,497,963
Diabetes Metab Syndr
COVID-19 and applications of smartphone technology in the current pandemic.
BACKGROUND: With restrictions on face to face clinical consultations in the COVID-19 pandemic and the challenges faced by health care systems in delivering patient care, alternative information technologies like telemedicine and smartphone are playing a key role. AIMS: We assess the role and applications of smartphone ...
covid-19;coronavirus;disease outbreaks;pandemic;smartphone;telemedicine
Journal Article;Review
Iyengar, Karthikeyan;Upadhyaya, Gaurav K;Vaishya, Raju;Jain, Vijay
10.1016/j.dsx.2020.05.033
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 and applications of smartphone technology in the current pandemic. [Abstract]: BACKGROUND: With restrictions on face to face clinical consultations in the COVID-19 pandemic and the challenges faced by health care systems in delivering patient care, alternative information technologies like telemedicin...
32,777,639
Thromb Res
D-dimer level is associated with the severity of COVID-19.
INTRODUCTION: Abnormal coagulation function has been demonstrated to be involved in the disease progression of COVID-19. However, the association between D-dimer levels and the severity of COVID-19 is not clear. The study was aimed to investigate the association between D-dimer levels and the severity of COVID-19 based...
covid-19;d-dimer;severity
Journal Article;Meta-Analysis
Yu, Hai-Han;Qin, Chuan;Chen, Man;Wang, Wei;Tian, Dai-Shi
10.1016/j.thromres.2020.07.047
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: D-dimer level is associated with the severity of COVID-19. [Abstract]: INTRODUCTION: Abnormal coagulation function has been demonstrated to be involved in the disease progression of COVID-19. However, the association between D-dimer levels and the severity of COVID-19 is not clear. The study was aimed to inves...
32,904,861
Hepatol Commun
Antibody response to SARS-Co-V-2, diagnostic and therapeutic implications.
The immune response against SARS-CoV-2 is comprised of both cellular and humoral arms. While current diagnostic methods are mainly based on PCR, they suffer from insensitivity. Therefore, antibody-based serological tests are being developed to achieve higher sensitivity and specificity. Current efforts in treating SARS...
covid-19;sars-cov-2;antibodies;hyperimmune globulin;immune response
Journal Article;Review
Ishay, Yuval;Kessler, Asa;Schwarts, Asaf;Ilan, Yaron
10.1002/hep4.1600
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Antibody response to SARS-Co-V-2, diagnostic and therapeutic implications. [Abstract]: The immune response against SARS-CoV-2 is comprised of both cellular and humoral arms. While current diagnostic methods are mainly based on PCR, they suffer from insensitivity. Therefore, antibody-based serological tests are...
32,737,043
Cleve Clin J Med
Thoracic imaging in COVID-19.
The typical findings of COVID-19 on chest radiography and computed tomography (CT) include bilateral, multifocal parenchymal opacities (ground-glass opacities with or without consolidation, and "crazy paving"). In most cases, the opacities are predominantly in the peripheral and lower lung zones, and several have round...
Journal Article
Yadav, Ruchi;Sahoo, Debasis;Graham, Ruffin
10.3949/ccjm.87a.ccc032
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Thoracic imaging in COVID-19. [Abstract]: The typical findings of COVID-19 on chest radiography and computed tomography (CT) include bilateral, multifocal parenchymal opacities (ground-glass opacities with or without consolidation, and "crazy paving"). In most cases, the opacities are predominantly in the peri...
32,354,770
J Neurol Neurosurg Psychiatry
Status of SARS-CoV-2 in cerebrospinal fluid of patients with COVID-19 and stroke.
BACKGROUND: Emergence of the novel corona virus (severe acute respiratory syndrome (SARS)-CoV-2) in December 2019 has led to the COVID-19 pandemic. The extent of COVID-19 involvement in the central nervous system is not well established, and the presence or the absence of SARS-CoV-2 particles in the cerebrospinal fluid...
csf;cerebrovascular disease;infectious diseases;stroke;subarachnoid haemorrhage
Case Reports;Journal Article
Al Saiegh, Fadi;Ghosh, Ritam;Leibold, Adam;Avery, Michael B;Schmidt, Richard F;Theofanis, Thana;Mouchtouris, Nikolaos;Philipp, Lucas;Peiper, Stephen C;Wang, Zi-Xuan;Rincon, Fred;Tjoumakaris, Stavropoula I;Jabbour, Pascal;Rosenwasser, Robert H;Gooch, M Reid
10.1136/jnnp-2020-323522
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Status of SARS-CoV-2 in cerebrospinal fluid of patients with COVID-19 and stroke. [Abstract]: BACKGROUND: Emergence of the novel corona virus (severe acute respiratory syndrome (SARS)-CoV-2) in December 2019 has led to the COVID-19 pandemic. The extent of COVID-19 involvement in the central nervous system is n...
32,383,520
BJU Int
Society of Robotic Surgery review: recommendations regarding the risk of COVID-19 transmission during minimally invasive surgery.
OBJECTIVES: To determine the risk of COVID-19 transmission during minimally invasive surgical (MIS) procedures METHODS: Surgical society statements regarding the risk of COVID transmission during MIS procedures were reviewed. In addition, the available literature on COVID-19 and other viral transmission in CO2 pneumope...
covid-19;sars-cov-2;coronavirus;laparoscopy;robotics;urology
Journal Article;Review
Porter, James;Blau, Elliot;Gharagozloo, Farid;Martino, Martin;Cerfolio, Robert;Duvvuri, Umamaheswar;Caceres, Aileen;Badani, Ketan;Bhayani, Sam;Collins, Justin;Coelho, Rafael;Rocco, Bernard;Wiklund, Peter;Nathan, Senthil;Parra-Davila, Eduardo;Ortiz-Ortiz, Carlos;Maes, Kris;Dasgupta, Prokar;Patel, Vipul
10.1111/bju.15105
[ 0, 0, 1, 0, 1, 0, 0 ]
[Title]: Society of Robotic Surgery review: recommendations regarding the risk of COVID-19 transmission during minimally invasive surgery. [Abstract]: OBJECTIVES: To determine the risk of COVID-19 transmission during minimally invasive surgical (MIS) procedures METHODS: Surgical society statements regarding the risk of...
32,461,408
Indian J Ophthalmol
All India Ophthalmological Society - Oculoplastics Association of India consensus statement on preferred practices in oculoplasty and lacrimal surgery during the COVID-19 pandemic.
Oculoplastic surgeries encompass both emergency surgeries for traumatic conditions and infectious disorders as well as elective aesthetic procedures. The COVID-19 pandemic has brought about a drastic change in this practice. Given the highly infectious nature of the disease as well as the global scarcity of medical res...
blepharoplasty;dcr;botox;corona;coronavirus;dacryocystorhinostomy;eyelid surgery;guidelines;lockdown;ophthalmology;orbital surgery;precautions;ptosis
Journal Article;Practice Guideline
Ali, Mohammad Javed;Hegde, Raghuraj;Nair, Akshay Gopinathan;Bajaj, Mandeep S;Betharia, Subhash M;Bhattacharjee, Kasturi;Chhabra, Apjit K;Das, Jayanta K;Dudeja, Gagan;Grover, Ashok K;Honavar, Santosh G;Kim, Usha;Mahesh, Lakshmi;Mukherjee, Bipasha;Sethi, Anita;Sharma, Mukesh;Singh, Usha
10.4103/ijo.IJO_1415_20
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: All India Ophthalmological Society - Oculoplastics Association of India consensus statement on preferred practices in oculoplasty and lacrimal surgery during the COVID-19 pandemic. [Abstract]: Oculoplastic surgeries encompass both emergency surgeries for traumatic conditions and infectious disorders as well as...
32,931,914
J Am Coll Surg
Impact of the COVID-19 Pandemic on Surgical Training and Learner Well-Being: Report of a Survey of General Surgery and Other Surgical Specialty Educators.
BACKGROUND: The COVID-19 pandemic disrupted the delivery of surgical services. The purpose of this communication was to report the impact of the pandemic on surgical training and learner well-being and to document adaptations made by surgery departments. STUDY DESIGN: A 37-item survey was distributed to educational lea...
Journal Article
Ellison, E Christopher;Spanknebel, Kathryn;Stain, Steven C;Shabahang, Mohsen M;Matthews, Jeffrey B;Debas, Haile T;Nagler, Alisa;Blair, Patrice Gabler;Eberlein, Timothy J;Farmer, Diana L;Sloane, Richard;Britt, L D;Sachdeva, Ajit K
10.1016/j.jamcollsurg.2020.08.766
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Impact of the COVID-19 Pandemic on Surgical Training and Learner Well-Being: Report of a Survey of General Surgery and Other Surgical Specialty Educators. [Abstract]: BACKGROUND: The COVID-19 pandemic disrupted the delivery of surgical services. The purpose of this communication was to report the impact of the...
32,425,317
Auris Nasus Larynx
The impact of preoperative screening system on head and neck cancer surgery during the COVID-19 pandemic: Recommendations from the nationwide survey in Japan.
Objective: the pandemic of coronavirus disease 2019 (COVID-19), hospitals worldwide are at risk of nosocomial infection. Preoperative identification of COVID-19 in patients who are scheduled to be admitted to the hospital is essential to preventing the collapse of medical facility. In Japan, the preoperative observatio...
covid-19;chest ct scan;head and neck cancer;rt-pcr;sars-cov-2
Journal Article
Ota, Ichiro;Asada, Yukinori
10.1016/j.anl.2020.05.006
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The impact of preoperative screening system on head and neck cancer surgery during the COVID-19 pandemic: Recommendations from the nationwide survey in Japan. [Abstract]: Objective: the pandemic of coronavirus disease 2019 (COVID-19), hospitals worldwide are at risk of nosocomial infection. Preoperative identi...
32,321,075
Cad Saude Publica
COVID-19 and hospitalizations for SARI in Brazil: a comparison up to the 12th epidemiological week of 2020.
Surveillance of the severe acute respiratory illness (SARI) in Brazil aims to characterize the circulation of the Influenza A and B viruses in hospitalized cases and deaths, having been expanded in 2012 to include other respiratory viruses. COVID-19 was detected in Brazil for the time in the 9th epidemiological week of...
Comparative Study;Journal Article
Bastos, Leonardo Soares;Niquini, Roberta Pereira;Lana, Raquel Martins;Villela, Daniel A M;Cruz, Oswaldo G;Coelho, Flavio C;Codeco, Claudia T;Gomes, Marcelo F C
10.1590/0102-311X00070120
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 and hospitalizations for SARI in Brazil: a comparison up to the 12th epidemiological week of 2020. [Abstract]: Surveillance of the severe acute respiratory illness (SARI) in Brazil aims to characterize the circulation of the Influenza A and B viruses in hospitalized cases and deaths, having been expan...
32,624,074
Epidemiol Infect
Dynamic evolution of lung abnormalities evaluated by quantitative CT techniques in patients with COVID-19 infection.
Chest CT evaluation is often vital to determine patients suspected of COVID-19 pneumonia. The aim of this study was to determine the evolution of lung abnormalities evaluated by quantitative CT techniques in patients with COVID-19 infection from initial diagnosis to recovery. This retrospective study included 16 patien...
covid-19;computed tomography;lung;novel coronavirus pneumonia
Journal Article
Feng, Xinglong;Ding, Xuemei;Zhang, Fuzhou
10.1017/S0950268820001508
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Dynamic evolution of lung abnormalities evaluated by quantitative CT techniques in patients with COVID-19 infection. [Abstract]: Chest CT evaluation is often vital to determine patients suspected of COVID-19 pneumonia. The aim of this study was to determine the evolution of lung abnormalities evaluated by quan...
33,046,960
Atmos Pollut Res
How do low wind speeds and high levels of air pollution support the spread of COVID-19?
The pandemic of coronavirus disease 2019 (COVID-19) is generating a high number of total infected individuals and deaths. One of the current questions is how climatological factors and environmental pollution can affect the diffusion of COVID-19 in human society. This study endeavours to explain the relation between wi...
air pollution;air quality;atmospheric pollution;covid-19;coronavirus disease;environment and health;environmental policy;particulate matter;public health;sars-cov-2;urban environment;wind speed
Journal Article
Coccia, Mario
10.1016/j.apr.2020.10.002
[ 0, 0, 0, 0, 1, 0, 0 ]
[Title]: How do low wind speeds and high levels of air pollution support the spread of COVID-19? [Abstract]: The pandemic of coronavirus disease 2019 (COVID-19) is generating a high number of total infected individuals and deaths. One of the current questions is how climatological factors and environmental pollution ca...
32,198,501
Clin Infect Dis
Profiling Early Humoral Response to Diagnose Novel Coronavirus Disease (COVID-19).
BACKGROUND: The emergence of coronavirus disease 2019 (COVID-19) is a major healthcare threat. The current method of detection involves a quantitative polymerase chain reaction (qPCR)-based technique, which identifies the viral nucleic acids when present in sufficient quantity. False-negative results can be achieved an...
covid-19;elisa;antibody;diagnosis;novel coronavirus
Journal Article;Research Support, Non-U.S. Gov't
Guo, Li;Ren, Lili;Yang, Siyuan;Xiao, Meng;Chang, De;Yang, Fan;Dela Cruz, Charles S;Wang, Yingying;Wu, Chao;Xiao, Yan;Zhang, Lulu;Han, Lianlian;Dang, Shengyuan;Xu, Yan;Yang, Qi-Wen;Xu, Sheng-Yong;Zhu, Hua-Dong;Xu, Ying-Chun;Jin, Qi;Sharma, Lokesh;Wang, Linghang;Wang, Jianwei
10.1093/cid/ciaa310
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Profiling Early Humoral Response to Diagnose Novel Coronavirus Disease (COVID-19). [Abstract]: BACKGROUND: The emergence of coronavirus disease 2019 (COVID-19) is a major healthcare threat. The current method of detection involves a quantitative polymerase chain reaction (qPCR)-based technique, which identifie...
32,853,291
PLoS Pathog
Development and evaluation of a rapid CRISPR-based diagnostic for COVID-19.
The recent outbreak of human infections caused by SARS-CoV-2, the third zoonotic coronavirus has raised great public health concern globally. Rapid and accurate diagnosis of this novel pathogen posts great challenges not only clinically but also technologically. Metagenomic next-generation sequencing (mNGS) and reverse...
Comparative Study;Journal Article;Research Support, Non-U.S. Gov't
Hou, Tieying;Zeng, Weiqi;Yang, Minling;Chen, Wenjing;Ren, Lili;Ai, Jingwen;Wu, Ji;Liao, Yalong;Gou, Xuejing;Li, Yongjun;Wang, Xiaorui;Su, Hang;Gu, Bing;Wang, Jianwei;Xu, Teng
10.1371/journal.ppat.1008705
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Development and evaluation of a rapid CRISPR-based diagnostic for COVID-19. [Abstract]: The recent outbreak of human infections caused by SARS-CoV-2, the third zoonotic coronavirus has raised great public health concern globally. Rapid and accurate diagnosis of this novel pathogen posts great challenges not on...
32,838,164
SN Compr Clin Med
Involvement of Spike Protein, Furin, and ACE2 in SARS-CoV-2-Related Cardiovascular Complications.
The novel coronavirus disease 2019 (COVID-19) is a global epidemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). SARS-CoV-2 has a similar structure to severe acute respiratory syndrome coronavirus-1(SARS-CoV-1). The S protein on the surface of the virus is cleaved by host proprotein convertase...
ace2;covid-19;cardiovascular complications;furin;sars-cov-2;spike protein
Journal Article;Review
Ming, Yi;Qiang, Liu
10.1007/s42399-020-00400-2
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Involvement of Spike Protein, Furin, and ACE2 in SARS-CoV-2-Related Cardiovascular Complications. [Abstract]: The novel coronavirus disease 2019 (COVID-19) is a global epidemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). SARS-CoV-2 has a similar structure to severe acute respiratory...
32,969,967
Am J Phys Med Rehabil
Implementation and Patient Satisfaction of Telemedicine in Spine Physical Medicine and Rehabilitation Patients During the COVID-19 Shutdown.
OBJECTIVE: The aim of the study was to investigate the implementation and patient satisfaction of telemedicine visits in a physical medicine and rehabilitation spine practice during COVID-19. DESIGN: This is a prospective cohort study. RESULTS: Of 172 patients, 97.6% were very satisfied or satisfied (83.7% of the patie...
Journal Article
Bhuva, Sheena;Lankford, Craig;Patel, Nayan;Haddas, Ram
10.1097/PHM.0000000000001600
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Implementation and Patient Satisfaction of Telemedicine in Spine Physical Medicine and Rehabilitation Patients During the COVID-19 Shutdown. [Abstract]: OBJECTIVE: The aim of the study was to investigate the implementation and patient satisfaction of telemedicine visits in a physical medicine and rehabilitatio...
33,015,110
Front Med (Lausanne)
The Relationship Between Chest Imaging Findings and the Viral Load of COVID-19.
Purpose: We aimed to investigate the relationship between clinical characteristics, radiographic features, and the viral load of patients with coronavirus disease 2019 (COVID-19). Methods and Materials: We retrospectively collected 56 COVID-19 cases from two institutions in Hunan province, China. The basal clinical cha...
covid-19;ct;follow-up;margin;viral load
Journal Article
Zhao, Wei;He, Lei;Tang, Haoneng;Xie, Xingzhi;Tang, Lingli;Liu, Jun
10.3389/fmed.2020.558539
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: The Relationship Between Chest Imaging Findings and the Viral Load of COVID-19. [Abstract]: Purpose: We aimed to investigate the relationship between clinical characteristics, radiographic features, and the viral load of patients with coronavirus disease 2019 (COVID-19). Methods and Materials: We retrospective...
33,040,384
J Leukoc Biol
COVID-19 infection induces readily detectable morphologic and inflammation-related phenotypic changes in peripheral blood monocytes.
Excessive monocyte/macrophage activation with the development of a cytokine storm and subsequent acute lung injury, leading to acute respiratory distress syndrome (ARDS), is a feared consequence of infection with COVID-19. The ability to recognize and potentially intervene early in those patients at greatest risk of de...
covid-19;flow cytometry;forward scatter;monocyte;morphology
Journal Article;Multicenter Study;Research Support, Non-U.S. Gov't
Zhang, Dan;Guo, Rui;Lei, Lei;Liu, Hongjuan;Wang, Yawen;Wang, Yili;Qian, Hongbo;Dai, Tongxin;Zhang, Tianxiao;Lai, Yanjun;Wang, Jingya;Liu, Zhiqiang;Chen, Tianyan;He, Aili;O'Dwyer, Michael;Hu, Jinsong
10.1002/JLB.4HI0720-470R
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: COVID-19 infection induces readily detectable morphologic and inflammation-related phenotypic changes in peripheral blood monocytes. [Abstract]: Excessive monocyte/macrophage activation with the development of a cytokine storm and subsequent acute lung injury, leading to acute respiratory distress syndrome (AR...
32,646,731
Semergen
Prevalence of SARS-CoV-2 infection in general practitioners and nurses in primary care and nursing homes in the Healthcare Area of Leon and associated factors.
OBJECTIVE: To evaluate the prevalence of and factors associated with SARS-CoV-2 infection in general practitioners and nurses from primary care centers and nursing homes in the Healthcare Area of Leon (Spain). MATERIALS AND METHODS: Cross-sectional study in a convenience sample of professionals from 30 health centers a...
atencion primaria;enfermeras;general practitioner;medicos;nurses;nursing home;prevalence;prevalencia;primary care;residencias de ancianos;sars-cov-2
Journal Article
Martin, V;Fernandez-Villa, T;Lamuedra Gil de Gomez, M;Mencia-Ares, O;Rivero Rodriguez, A;Reguero Celada, S;Montoro Gomez, M;Nuevo Guisado, M T;Villa Aller, C;Diez Flecha, C;Carvajal, A;Fernandez Vazquez, J P
10.1016/j.semerg.2020.05.014
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Prevalence of SARS-CoV-2 infection in general practitioners and nurses in primary care and nursing homes in the Healthcare Area of Leon and associated factors. [Abstract]: OBJECTIVE: To evaluate the prevalence of and factors associated with SARS-CoV-2 infection in general practitioners and nurses from primary ...
32,403,995
Emerg Microbes Infect
Development of multi-specific humanized llama antibodies blocking SARS-CoV-2/ACE2 interaction with high affinity and avidity.
Coronaviruses cause severe human viral diseases including SARS, MERS and COVID-19. Most recently SARS-CoV-2 virus (causing COVID-19) has led to a pandemic with no successful therapeutics. The SARS-CoV-2 infection relies on trimeric spike (S) proteins to facilitate virus entry into host cells by binding to ACE2 receptor...
covid-19;sars-cov-2;bi-specific antibody;humanized antibody;llama antibody;nanobody;tri-specific antibody
Letter
Dong, Jianbo;Huang, Betty;Jia, Zhejun;Wang, Bo;Gallolu Kankanamalage, Sachith;Titong, Allison;Liu, Yue
10.1080/22221751.2020.1768806
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Development of multi-specific humanized llama antibodies blocking SARS-CoV-2/ACE2 interaction with high affinity and avidity. [Abstract]: Coronaviruses cause severe human viral diseases including SARS, MERS and COVID-19. Most recently SARS-CoV-2 virus (causing COVID-19) has led to a pandemic with no successful...
32,701,969
PLoS One
Safety, tolerability, and clinical outcomes of hydroxychloroquine for hospitalized patients with coronavirus 2019 disease.
BACKGROUND: Severe acute respiratory coronavirus 2 (SARS-CoV-2) has caused a devastating worldwide pandemic. Hydroxychloroquine (HCQ) has in vitro activity against SARS-CoV-2, but clinical data supporting HCQ for coronavirus disease 2019 (COVID-19) are limited. METHODS: This was a retrospective cohort study of hospital...
Journal Article;Multicenter Study;Observational Study;Research Support, N.I.H., Extramural
Satlin, Michael J;Goyal, Parag;Magleby, Reed;Maldarelli, Grace A;Pham, Khanh;Kondo, Maiko;Schenck, Edward J;Rennert, Hanna;Westblade, Lars F;Choi, Justin J;Safford, Monika M;Gulick, Roy M
10.1371/journal.pone.0236778
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Safety, tolerability, and clinical outcomes of hydroxychloroquine for hospitalized patients with coronavirus 2019 disease. [Abstract]: BACKGROUND: Severe acute respiratory coronavirus 2 (SARS-CoV-2) has caused a devastating worldwide pandemic. Hydroxychloroquine (HCQ) has in vitro activity against SARS-CoV-2, ...
32,898,341
ESC Heart Fail
Surface electrocardiographic characteristics in coronavirus disease 2019: repolarization abnormalities associated with cardiac involvement.
AIMS: The coronavirus disease 2019 (COVID-19) has spread rapidly around the globe, causing significant morbidity and mortality. This study aims to describe electrocardiographic (ECG) characteristics of COVID-19 patients and to identify ECG parameters that are associated with cardiac involvement. METHODS AND RESULTS: Th...
covid-19;clinical outcome;ecg;heart injury;repolarization
Journal Article
Chen, Liang;Feng, Yi;Tang, Jia;Hu, Wei;Zhao, Ping;Guo, Xiaoxiao;Huang, Ninghao;Gu, Yuwei;Hu, Linjie;Duru, Firat;Xiong, Chenglong;Chen, Mingquan
10.1002/ehf2.12991
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Surface electrocardiographic characteristics in coronavirus disease 2019: repolarization abnormalities associated with cardiac involvement. [Abstract]: AIMS: The coronavirus disease 2019 (COVID-19) has spread rapidly around the globe, causing significant morbidity and mortality. This study aims to describe ele...
32,864,608
JAC Antimicrob Resist
Bacterial pneumonia coinfection and antimicrobial therapy duration in SARS-CoV-2 (COVID-19) infection.
Background: Bacterial respiratory coinfection in the setting of SARS-CoV-2 infection remains poorly described. A description of coinfection and antimicrobial usage is needed to guide ongoing antimicrobial stewardship. Objectives: To assess the rate of empirical antimicrobial treatment in COVID-19 cases, assess the rate...
Journal Article
Townsend, Liam;Hughes, Gerry;Kerr, Colm;Kelly, Mary;O'Connor, Roisin;Sweeney, Eileen;Doyle, Catriona;O'Riordan, Ruth;Bergin, Colm;Bannan, Ciaran
10.1093/jacamr/dlaa071
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Bacterial pneumonia coinfection and antimicrobial therapy duration in SARS-CoV-2 (COVID-19) infection. [Abstract]: Background: Bacterial respiratory coinfection in the setting of SARS-CoV-2 infection remains poorly described. A description of coinfection and antimicrobial usage is needed to guide ongoing antim...
33,031,212
J Addict Med
Naloxone Use by Emergency Medical Services During the COVID-19 Pandemic: A National Survey.
OBJECTIVES: The COVID-19 epidemic in the United States has hit in the midst of the opioid overdose crisis. Emergency medical services (EMS) clinicians may limit their use of intranasal naloxone due to concerns of novel coronavirus infection. We sought to determine changes in overdose events and naloxone administration ...
Journal Article
Cone, David C;Bogucki, Sandy;Burns, Kevin;D'Onofrio, Gail;Hawk, Kathryn;Joseph, Daniel;Fiellin, David A
10.1097/ADM.0000000000000746
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Naloxone Use by Emergency Medical Services During the COVID-19 Pandemic: A National Survey. [Abstract]: OBJECTIVES: The COVID-19 epidemic in the United States has hit in the midst of the opioid overdose crisis. Emergency medical services (EMS) clinicians may limit their use of intranasal naloxone due to concer...
32,913,297
Nat Rev Microbiol
Prospects for SARS-CoV-2 diagnostics, therapeutics and vaccines in Africa.
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in a global pandemic, prompting unprecedented efforts to contain the virus. Many developed countries have implemented widespread testing and have rapidly mobilized research programmes to develop vaccines and therapeutics. However...
Journal Article;Review
Margolin, Emmanuel;Burgers, Wendy A;Sturrock, Edward D;Mendelson, Marc;Chapman, Rosamund;Douglass, Nicola;Williamson, Anna-Lise;Rybicki, Edward P
10.1038/s41579-020-00441-3
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Prospects for SARS-CoV-2 diagnostics, therapeutics and vaccines in Africa. [Abstract]: The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in a global pandemic, prompting unprecedented efforts to contain the virus. Many developed countries have implemented widespread test...
32,531,372
J Allergy Clin Immunol
Expression of SARS-CoV-2 receptor ACE2 and coincident host response signature varies by asthma inflammatory phenotype.
BACKGROUND: More than 300 million people carry a diagnosis of asthma, with data to suggest that they are at a higher risk for infection or adverse outcomes from severe acute respiratory syndrome coronavirus 2. Asthma is remarkably heterogeneous, and it is currently unclear how patient-intrinsic factors may relate to co...
ace2;covid-19;sars-cov-2;type-2 low;asthma;coronavirus;interferons;viral response
Journal Article;Multicenter Study;Research Support, N.I.H., Extramural
Camiolo, Matthew;Gauthier, Marc;Kaminski, Naftali;Ray, Anuradha;Wenzel, Sally E
10.1016/j.jaci.2020.05.051
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: Expression of SARS-CoV-2 receptor ACE2 and coincident host response signature varies by asthma inflammatory phenotype. [Abstract]: BACKGROUND: More than 300 million people carry a diagnosis of asthma, with data to suggest that they are at a higher risk for infection or adverse outcomes from severe acute respir...
32,419,646
J Biomol Struct Dyn
Design of multi-epitope vaccine candidate against SARS-CoV-2: a in-silico study.
The best therapeutic strategy to find an effective vaccine against SARS-CoV-2 is to explore the target structural protein. In the present study, a novel multi-epitope vaccine is designed using in silico tools that potentially trigger both CD4 and CD8 T-cell immune responses against the novel Coronavirus. The vaccine ca...
covid-19;iedb;vaxigen;immuno-informatics;spike glycoprotein;vaccine design
Journal Article
Abraham Peele, K;Srihansa, T;Krupanidhi, S;Ayyagari, Vijaya Sai;Venkateswarulu, T C
10.1080/07391102.2020.1770127
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Design of multi-epitope vaccine candidate against SARS-CoV-2: a in-silico study. [Abstract]: The best therapeutic strategy to find an effective vaccine against SARS-CoV-2 is to explore the target structural protein. In the present study, a novel multi-epitope vaccine is designed using in silico tools that pote...
32,413,909
Gesundheitswesen
[Protecting Medical Professionals from Infection During the Coronavirus Pandemic: Overnight Implementation of Virtual Medical Boards].
BACKGROUND: For medical professionals in hospitals, it is nearly impossible to abide by the rules of social distancing to prevent coronavirus transmission. In order to avoid unnecessary contact between medical staff, virtual medical boards were implemented. METHODS: Technical requirements for virtual boards were establ...
Journal Article
Konig, Tatjana Tamara;Lenz, Anna-Franziska;Goedeke, Jan;Muensterer, Oliver J
10.1055/a-1165-1878
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [Protecting Medical Professionals from Infection During the Coronavirus Pandemic: Overnight Implementation of Virtual Medical Boards]. [Abstract]: BACKGROUND: For medical professionals in hospitals, it is nearly impossible to abide by the rules of social distancing to prevent coronavirus transmission. In order...
32,311,036
J Am Med Inform Assoc
How hospitals in mainland China responded to the outbreak of COVID-19 using information technology-enabled services: An analysis of hospital news webpages.
OBJECTIVE: Many countries have implemented quarantine rules during the global outbreak of coronavirus disease 2019 (COVID-19). Understanding how hospitals can continue providing services in an effective manner under these circumstances is thus important. In this study, we investigate how information technology (IT) hel...
covid-19 pandemic;it-enabled services;mainland china;hospital responding strategy
Journal Article
Yan, Aihua;Zou, Yi;Mirchandani, Dinesh A
10.1093/jamia/ocaa064
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: How hospitals in mainland China responded to the outbreak of COVID-19 using information technology-enabled services: An analysis of hospital news webpages. [Abstract]: OBJECTIVE: Many countries have implemented quarantine rules during the global outbreak of coronavirus disease 2019 (COVID-19). Understanding ho...
32,715,310
Clin Chem
SARS-CoV-2 Whole Genome Amplification and Sequencing for Effective Population-Based Surveillance and Control of Viral Transmission.
BACKGROUND: With the gradual reopening of economies and resumption of social life, robust surveillance mechanisms should be implemented to control the ongoing COVID-19 pandemic. Unlike RT-qPCR, SARS-CoV-2 whole genome sequencing (cWGS) has the added advantage of identifying cryptic origins of the virus, and the extent ...
Journal Article;Research Support, Non-U.S. Gov't
Harilal, Divinlal;Ramaswamy, Sathishkumar;Loney, Tom;Suwaidi, Hanan Al;Khansaheb, Hamda;Alkhaja, Abdulmajeed;Varghese, Rupa;Deesi, Zulfa;Nowotny, Norbert;Alsheikh-Ali, Alawi;Abou Tayoun, Ahmad
10.1093/clinchem/hvaa187
[ 0, 1, 1, 1, 0, 0, 0 ]
[Title]: SARS-CoV-2 Whole Genome Amplification and Sequencing for Effective Population-Based Surveillance and Control of Viral Transmission. [Abstract]: BACKGROUND: With the gradual reopening of economies and resumption of social life, robust surveillance mechanisms should be implemented to control the ongoing COVID-19...
32,306,042
Clin Infect Dis
Testing for SARS-CoV-2: Can We Stop at 2?
The COVID-19 epidemic requires accurate identification and isolation of confirmed cases for effective control. This report describes the effectiveness of our testing strategy and highlights the importance of repeat testing in suspected cases in our cohort.
covid-19;sars-cov-2;diagnosis;polymerase chain reaction;testing
Case Reports;Journal Article
Lee, Tau Hong;Junhao Lin, Ray;Lin, Raymond T P;Barkham, Timothy;Rao, Pooja;Leo, Yee-Sin;Chien Lye, David;Young, Barnaby
10.1093/cid/ciaa459
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Testing for SARS-CoV-2: Can We Stop at 2? [Abstract]: The COVID-19 epidemic requires accurate identification and isolation of confirmed cases for effective control. This report describes the effectiveness of our testing strategy and highlights the importance of repeat testing in suspected cases in our cohort. ...
32,419,713
Ann Emerg Med
Preparedness and Response to Pediatric COVID-19 in European Emergency Departments: A Survey of the REPEM and PERUKI Networks.
Study objective: We aim to describe the variability and identify gaps in preparedness and response to the coronavirus disease 2019 pandemic in European emergency departments (EDs) caring for children. Methods: A cross-sectional point-prevalence survey was developed and disseminated through the pediatric emergency medic...
Journal Article
Bressan, Silvia;Buonsenso, Danilo;Farrugia, Ruth;Parri, Niccolo';Oostenbrink, Rianne;Titomanlio, Luigi;Roland, Damian;Nijman, Ruud G;Maconochie, Ian;Da Dalt, Liviana;Mintegi, Santiago
10.1016/j.annemergmed.2020.05.018
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Preparedness and Response to Pediatric COVID-19 in European Emergency Departments: A Survey of the REPEM and PERUKI Networks. [Abstract]: Study objective: We aim to describe the variability and identify gaps in preparedness and response to the coronavirus disease 2019 pandemic in European emergency departments...
32,837,839
Z Gesundh Wiss
Homeopathy combat against coronavirus disease (Covid-19).
Aim: Today, humanity is living through the third serious coronavirus outbreak in less than 20 years, following SARS in 2002-2003 and MERS in 2012. While the final cost on human lives and world economy remains unpredictable, the timely identification of a suitable treatment and the development of an effective vaccine re...
coronavirus;covid-19;homeopathy;infectious disease;laws;pneumonia
Journal Article
Kalliantas, D;Kallianta, M;Karagianni, Ch S
10.1007/s10389-020-01305-z
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Homeopathy combat against coronavirus disease (Covid-19). [Abstract]: Aim: Today, humanity is living through the third serious coronavirus outbreak in less than 20 years, following SARS in 2002-2003 and MERS in 2012. While the final cost on human lives and world economy remains unpredictable, the timely identi...
32,979,670
Am J Otolaryngol
A survey of personal protective equipment use among US otolaryngologists during the COVID-19 pandemic.
OBJECTIVE: Describe current practices and challenges in personal protective equipment (PPE) use among US otolaryngologists during the COVID-19 pandemic. STUDY DESIGN: Online survey. SETTING: Academic and non-academic healthcare institutions. SUBJECTS AND METHODS: Subjects included US otolaryngology physicians. Emails w...
covid-19;personal protective equipment;sars-cov-2
Journal Article
Yu, Karina;Micco, Alan G;Ference, Elisabeth;Levy, Joshua M;Smith, Stephanie Shintani
10.1016/j.amjoto.2020.102735
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: A survey of personal protective equipment use among US otolaryngologists during the COVID-19 pandemic. [Abstract]: OBJECTIVE: Describe current practices and challenges in personal protective equipment (PPE) use among US otolaryngologists during the COVID-19 pandemic. STUDY DESIGN: Online survey. SETTING: Acade...
32,994,158
J Surg Educ
Virtual Surgery Oral Board Examinations in the Era of COVID-19 Pandemic. How I Do It!
INTRODUCTION: Traditional in-person Mock Oral Examinations (IP-MOEs) are utilized by surgery residency programs to prepare trainees for the American Board of Surgery Certifying Exam (ABS-CE). However, the COVID-19 Pandemic has led to a profound disruption of on-campus and in-person educational activities, with subseque...
american board of surgery certifying examination;mock orals;oral examination;virtual exams
Journal Article
Shebrain, Saad;Nava, Kristofer;Munene, Gitonga;Shattuck, Cynthia;Collins, John;Sawyer, Robert
10.1016/j.jsurg.2020.09.012
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Virtual Surgery Oral Board Examinations in the Era of COVID-19 Pandemic. How I Do It! [Abstract]: INTRODUCTION: Traditional in-person Mock Oral Examinations (IP-MOEs) are utilized by surgery residency programs to prepare trainees for the American Board of Surgery Certifying Exam (ABS-CE). However, the COVID-19...
32,713,060
Nephrology (Carlton)
Impact of COVID-19 on maintenance haemodialysis patients: The Indian scenario.
There is a lack of data describing the impact of the novel coronavirus 19 pandemic on the patients of chronic kidney disease stage V-dialysis (CKD V-D) from resource-limited countries. A growing body of literature describes an increased susceptibility of CKD V-D to COVID-19 with adverse outcomes in those with severe di...
covid-19;dialysis;renal replacement therapy
Journal Article
Trivedi, Mayuri;Shingada, Aakash;Shah, Meera;Khanna, Umesh;Karnik, Niteen D;Ramachandran, Raja
10.1111/nep.13760
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Impact of COVID-19 on maintenance haemodialysis patients: The Indian scenario. [Abstract]: There is a lack of data describing the impact of the novel coronavirus 19 pandemic on the patients of chronic kidney disease stage V-dialysis (CKD V-D) from resource-limited countries. A growing body of literature descri...
33,007,954
Diagnostics (Basel)
Potential Trends of Point-of-Care Diagnostics-The Next Generation of the Laboratory Diagnosis.
With the current worldwide outbreak of COVID-19, developing rapid, effective, and convenient detection tools has become imperative [...].
Editorial
Lin, Sheng-Wen;Shen, Ching-Fen;Cheng, Chao-Min
10.3390/diagnostics10100774
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Potential Trends of Point-of-Care Diagnostics-The Next Generation of the Laboratory Diagnosis. [Abstract]: With the current worldwide outbreak of COVID-19, developing rapid, effective, and convenient detection tools has become imperative [...]. [Keywords]:
32,238,757
J Microbiol Biotechnol
Current Status of Epidemiology, Diagnosis, Therapeutics, and Vaccines for Novel Coronavirus Disease 2019 (COVID-19).
Coronavirus disease 2019 (COVID-19), which causes serious respiratory illness such as pneumonia and lung failure, was first reported in Wuhan, the capital of Hubei, China. The etiological agent of COVID-19 has been confirmed as a novel coronavirus, now known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-...
2019-ncov;covid-19;sars-cov-2;coronavirus;outbreak
Journal Article;Review
Ahn, Dae-Gyun;Shin, Hye-Jin;Kim, Mi-Hwa;Lee, Sunhee;Kim, Hae-Soo;Myoung, Jinjong;Kim, Bum-Tae;Kim, Seong-Jun
10.4014/jmb.2003.03011
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Current Status of Epidemiology, Diagnosis, Therapeutics, and Vaccines for Novel Coronavirus Disease 2019 (COVID-19). [Abstract]: Coronavirus disease 2019 (COVID-19), which causes serious respiratory illness such as pneumonia and lung failure, was first reported in Wuhan, the capital of Hubei, China. The etiolo...
32,828,653
J Cardiothorac Vasc Anesth
A Case Series of Devastating Intracranial Hemorrhage During Venovenous Extracorporeal Membrane Oxygenation for COVID-19.
OBJECTIVE: Anticoagulation may be a challenge in coronavirus disease 2019 (COVID-19) extracorporeal membrane oxygenation due to endothelial injury and dysregulation of coagulation, which may increase the risk of thrombotic and bleeding complications. This report was created to describe the authors' single institutional...
covid-19;sars-cov-2;anticoagulation;extracorporeal membrane oxygenation;intraparenchymal hemorrhage;stroke
Journal Article
Usman, Asad Ali;Han, Jason;Acker, Andrew;Olia, Salim E;Bermudez, Christian;Cucchiara, Brett;Mikkelsen, Mark E;Wald, Joyce;Mackay, Emily;Szeto, Wilson;Vernick, William J;Gutsche, Jacob T
10.1053/j.jvca.2020.07.063
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: A Case Series of Devastating Intracranial Hemorrhage During Venovenous Extracorporeal Membrane Oxygenation for COVID-19. [Abstract]: OBJECTIVE: Anticoagulation may be a challenge in coronavirus disease 2019 (COVID-19) extracorporeal membrane oxygenation due to endothelial injury and dysregulation of coagulatio...
33,027,092
Clin Spine Surg
Safe Spine Surgery During the COVID-19 Pandemic.
Safe spine surgery is possible during the COVID-19 pandemic. Certain urgent procedures must still be performed during this challenging time to prevent permanent long-term disability or death for patients. Precautions must be taken in the operating room to optimize safety, including the use of personal protective equipm...
Journal Article;Review
Toombs, Courtney S;Boody, Barrett S;Bronson, Wesley H;Girasole, Gerard J;Russo, Glenn S
10.1097/BSD.0000000000001084
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Safe Spine Surgery During the COVID-19 Pandemic. [Abstract]: Safe spine surgery is possible during the COVID-19 pandemic. Certain urgent procedures must still be performed during this challenging time to prevent permanent long-term disability or death for patients. Precautions must be taken in the operating ro...
32,864,278
Cureus
A Case of COVID-19 With Memory Impairment and Delayed Presentation as Stroke.
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a respiratory pathogen with remarkable properties of multisystem involvement and numerous complications. The coronavirus disease of 2019 (COVID-19) presenting as stroke is becoming more common. Herein, we describe an unusual case of COVID-19 in a patie...
covid-19;cycle threshold;ischemic cva;memory issues;sars-cov-2 (severe acute respiratory syndrome coronavirus -2);stroke;stroke recrudescence
Case Reports
Garg, Alpana;Marji, Amin;Goyal, Sachin;Ismail, Rana
10.7759/cureus.10025
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: A Case of COVID-19 With Memory Impairment and Delayed Presentation as Stroke. [Abstract]: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a respiratory pathogen with remarkable properties of multisystem involvement and numerous complications. The coronavirus disease of 2019 (COVID-19) prese...
32,858,292
Sci Total Environ
Particulate matter and SARS-CoV-2: A possible model of COVID-19 transmission.
Coronavirus disease 2019 (COVID-19), an acute respiratory disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly developed into a pandemic throughout the world. This disease is a highly infectious novel coronavirus and can affect people of all ages. Previous reports observed tha...
air pollution;angiotensin-converting enzyme 2;covid-19;sars-cov-2
Letter
Tung, Nguyen Thanh;Cheng, Po-Ching;Chi, Kai-Hsien;Hsiao, Ta-Chi;Jones, Timothy;BeruBe, Kelly;Ho, Kin-Fai;Chuang, Hsiao-Chi
10.1016/j.scitotenv.2020.141532
[ 0, 0, 0, 1, 1, 0, 0 ]
[Title]: Particulate matter and SARS-CoV-2: A possible model of COVID-19 transmission. [Abstract]: Coronavirus disease 2019 (COVID-19), an acute respiratory disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly developed into a pandemic throughout the world. This disease is a h...
32,922,409
Front Immunol
Treatment of COVID-19 With Conestat Alfa, a Regulator of the Complement, Contact Activation and Kallikrein-Kinin System.
A dysregulated immune response with hyperinflammation is observed in patients with severe coronavirus disease 2019 (COVID-19). The aim of the present study was to assess the safety and potential benefits of human recombinant C1 esterase inhibitor (conestat alfa), a complement, contact activation and kallikrein-kinin sy...
c1 esterase inhibitor;covid-19;sars-cov-2;complement system;contact activation system;inflammation;kallikrein-kinin system
Journal Article
Urwyler, Pascal;Moser, Stephan;Charitos, Panteleimon;Heijnen, Ingmar A F M;Rudin, Melanie;Sommer, Gregor;Giannetti, Bruno M;Bassetti, Stefano;Sendi, Parham;Trendelenburg, Marten;Osthoff, Michael
10.3389/fimmu.2020.02072
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Treatment of COVID-19 With Conestat Alfa, a Regulator of the Complement, Contact Activation and Kallikrein-Kinin System. [Abstract]: A dysregulated immune response with hyperinflammation is observed in patients with severe coronavirus disease 2019 (COVID-19). The aim of the present study was to assess the safe...
32,551,760
Psychol Trauma
Commentary on the coronavirus pandemic: Nigeria.
About a week after the confirmation of Nigeria's index case of COVID-19 on February 27, 2020, the Nigerian federal government set up a 12-member Presidential Task Force for the Control of the Coronavirus. The country's borders were closed on March 23, and the lockdown of cities was also implemented. The unanticipated d...
Journal Article
Chukwuorji, JohnBosco Chika;Iorfa, Steven Kator
10.1037/tra0000786
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Commentary on the coronavirus pandemic: Nigeria. [Abstract]: About a week after the confirmation of Nigeria's index case of COVID-19 on February 27, 2020, the Nigerian federal government set up a 12-member Presidential Task Force for the Control of the Coronavirus. The country's borders were closed on March 23...
32,794,685
Cornea
A Patient with Bilateral Conjunctivitis Positive for Sars-Cov-2 RNA in Conjunctival Sample.
PURPOSE: To present a patient with bilateral conjunctivitis testing positive for viral RNA of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in both nasopharyngeal and conjunctival samples. METHODS: A 40-year-old man with bilateral acute conjunctivitis and no suspicious signs of coronavirus disease 2019 (...
Case Reports;Journal Article
Sirakaya, Ender;Sahiner, Mustafa;Sirakaya, Hatice Aslan
10.1097/ICO.0000000000002485
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: A Patient with Bilateral Conjunctivitis Positive for Sars-Cov-2 RNA in Conjunctival Sample. [Abstract]: PURPOSE: To present a patient with bilateral conjunctivitis testing positive for viral RNA of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in both nasopharyngeal and conjunctival samples. MET...
32,996,774
Am J Physiol Lung Cell Mol Physiol
Vitamin D supplementation as a rational pharmacological approach in the COVID-19 pandemic.
The COVID-19 pandemic has reached most of the countries worldwide causing death, which often results from an inflammatory storm associated with severe acute respiratory syndrome (SARS). This has prompted researchers to seek specific novel and definitive treatments urgently. In this context, it is interesting to evaluat...
covid-19;inflammation;oxidative stress;renin-angiotensin system;vitamin d
Journal Article;Research Support, Non-U.S. Gov't;Review
Ferder, Leon;Martin Gimenez, Virna Margarita;Inserra, Felipe;Tajer, Carlos;Antonietti, Laura;Mariani, Javier;Manucha, Walter
10.1152/ajplung.00186.2020
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Vitamin D supplementation as a rational pharmacological approach in the COVID-19 pandemic. [Abstract]: The COVID-19 pandemic has reached most of the countries worldwide causing death, which often results from an inflammatory storm associated with severe acute respiratory syndrome (SARS). This has prompted rese...
32,849,415
Front Microbiol
Sequencing the Genome of Indian Flying Fox, Natural Reservoir of Nipah Virus, Using Hybrid Assembly and Conservative Secondary Scaffolding.
Indian fruit bats, flying fox Pteropus medius was identified as an asymptomatic natural host of recently emerged Nipah virus, which is known to induce a severe infectious disease in humans. The absence of P. medius genome sequence presents an important obstacle for further studies of virus-host interactions and better ...
nipah virus;pteropus giganteus;pteropus medius;bats;hybrid genome assembly;secondary scaffolding
Journal Article
Fouret, Julien;Brunet, Frederic G;Binet, Martin;Aurine, Noemie;Enchery, Francois;Croze, Severine;Guinier, Marie;Goumaidi, Abdelghafar;Preininger, Doris;Volff, Jean-Nicolas;Bailly-Bechet, Marc;Lachuer, Joel;Horvat, Branka;Legras-Lachuer, Catherine
10.3389/fmicb.2020.01807
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Sequencing the Genome of Indian Flying Fox, Natural Reservoir of Nipah Virus, Using Hybrid Assembly and Conservative Secondary Scaffolding. [Abstract]: Indian fruit bats, flying fox Pteropus medius was identified as an asymptomatic natural host of recently emerged Nipah virus, which is known to induce a severe...
33,047,877
Microb Biotechnol
Repositioning microbial biotechnology against COVID-19: the case of microbial production of flavonoids.
Coronavirus-related disease 2019 (COVID-19) became a pandemic in February 2020, and worldwide researchers try to tackle the disease with approved drugs of all kinds, or to develop novel compounds inhibiting viral spreading. Flavonoids, already investigated as antivirals in general, also might bear activities specific f...
Journal Article;Research Support, Non-U.S. Gov't;Review
Goris, Tobias;Perez-Valero, Alvaro;Martinez, Igor;Yi, Dong;Fernandez-Calleja, Luis;San Leon, David;Bornscheuer, Uwe T;Magadan-Corpas, Patricia;Lombo, Felipe;Nogales, Juan
10.1111/1751-7915.13675
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Repositioning microbial biotechnology against COVID-19: the case of microbial production of flavonoids. [Abstract]: Coronavirus-related disease 2019 (COVID-19) became a pandemic in February 2020, and worldwide researchers try to tackle the disease with approved drugs of all kinds, or to develop novel compounds...
32,426,387
Biomed J
Artificial intelligence approach fighting COVID-19 with repurposing drugs.
Background: The ongoing COVID-19 pandemic has caused more than 193,825 deaths during the past few months. A quick-to-be-identified cure for the disease will be a therapeutic medicine that has prior use experiences in patients in order to resolve the current pandemic situation before it could become worsening. Artificia...
ai;covid-19;dnn;drug repurposing;feline coronavirus;sars-cov-2
Journal Article
Ke, Yi-Yu;Peng, Tzu-Ting;Yeh, Teng-Kuang;Huang, Wen-Zheng;Chang, Shao-En;Wu, Szu-Huei;Hung, Hui-Chen;Hsu, Tsu-An;Lee, Shiow-Ju;Song, Jeng-Shin;Lin, Wen-Hsing;Chiang, Tung-Jung;Lin, Jiunn-Horng;Sytwu, Huey-Kang;Chen, Chiung-Tong
10.1016/j.bj.2020.05.001
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Artificial intelligence approach fighting COVID-19 with repurposing drugs. [Abstract]: Background: The ongoing COVID-19 pandemic has caused more than 193,825 deaths during the past few months. A quick-to-be-identified cure for the disease will be a therapeutic medicine that has prior use experiences in patient...
32,309,809
Arch Acad Emerg Med
Antiviral therapy in management of COVID-19: a systematic review on current evidence.
Background: The purpose of the current systematic review is to evaluate the efficacy of antiviral therapies in treatment of COVID-19. In addition, clinical trials on the efficacy of antiviral therapies in the management of Severe Acute Respiratory Syndrome coronavirus (SARS-Cov) or Middle East Respiratory Syndrome coro...
antiviral therapy;covid-19;treatment
Journal Article;Review
Yousefifard, Mahmoud;Zali, Alireza;Mohamed Ali, Kosar;Madani Neishaboori, Arian;Zarghi, Afshin;Hosseini, Mostafa;Safari, Saeed
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Antiviral therapy in management of COVID-19: a systematic review on current evidence. [Abstract]: Background: The purpose of the current systematic review is to evaluate the efficacy of antiviral therapies in treatment of COVID-19. In addition, clinical trials on the efficacy of antiviral therapies in the mana...
32,874,996
Orthop J Sports Med
The Impact of COVID-19 on the Sports Medicine Fellowship Class of 2020.
Background: In response to the COVID-19 pandemic, many US health systems suspended elective surgery at the recommendation of the US Surgeon General. This dramatically decreased case volumes for orthopaedic sports medicine fellows at academic institutions. Purpose: To describe how the COVID-19 pandemic has affected the ...
covid-19;coronavirus;education;epidemiology;fellowship;pandemic
Journal Article
Perrone, Michael A;Youssefzadeh, Keon;Serrano, Brian;Limpisvasti, Orr;Banffy, Michael
10.1177/2325967120939901
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The Impact of COVID-19 on the Sports Medicine Fellowship Class of 2020. [Abstract]: Background: In response to the COVID-19 pandemic, many US health systems suspended elective surgery at the recommendation of the US Surgeon General. This dramatically decreased case volumes for orthopaedic sports medicine fello...
32,852,576
Pediatr Nephrol
COVID-19 associated with onset nephrotic syndrome in a pediatric patient: coincidence or related conditions?
BACKGROUND: COVID-19 is less frequent in children than in adults and affects the former less severely; despite the fact that respiratory symptoms are the most frequent, in some cases unusual manifestations can be seen. CASE-DIAGNOSIS: We present a 15-year-old boy who tested positive for SARS-COV-2 infection and onset o...
adolescent;covid-19;nephrotic syndrome;proteinuria;sars-cov-2
Case Reports;Journal Article
Alvarado, Amado;Franceschi, Gabriela;Resplandor, Evelin;Sumba, Jeannethe;Orta, Nelson
10.1007/s00467-020-04724-y
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: COVID-19 associated with onset nephrotic syndrome in a pediatric patient: coincidence or related conditions? [Abstract]: BACKGROUND: COVID-19 is less frequent in children than in adults and affects the former less severely; despite the fact that respiratory symptoms are the most frequent, in some cases unusual...
32,713,282
Ren Fail
COVID-19: a novel menace for the practice of nephrology and how to manage it with minor devastation?
Coronavirus disease 19 (COVID-19) became a nightmare for the world since December 2019. Although the disease affects people at any age; elderly patients and those with comorbidities were more affected. Everyday nephrologists see patients with hypertension, chronic kidney disease, maintenance dialysis treatment or kidne...
covid-19;acute kidney injury;glomerulonephritis;hemodialysis;hypertension;renal transplantation
Journal Article;Review
Ulu, Sena;Gungor, Ozkan;Gok Oguz, Ebru;Hasbal, Nuri Baris;Turgut, Didem;Arici, Mustafa
10.1080/0886022X.2020.1797791
[ 1, 1, 1, 1, 0, 0, 0 ]
[Title]: COVID-19: a novel menace for the practice of nephrology and how to manage it with minor devastation? [Abstract]: Coronavirus disease 19 (COVID-19) became a nightmare for the world since December 2019. Although the disease affects people at any age; elderly patients and those with comorbidities were more affect...
32,657,818
Am J Phys Med Rehabil
The Down Side of Prone Positioning: The Case of a Coronavirus 2019 Survivor.
The coronavirus 2019 pandemic has resulted in a surge of patients with acute respiratory distress syndrome. Prone positioning may be used in such patients to optimize oxygenation. Severe infections may leave survivors with significant functional impairment necessitating rehabilitation. Those who have experienced prolon...
Case Reports;Journal Article;Review
Le, Minh Quan;Rosales, Richard;Shapiro, Lauren T;Huang, Laura Y
10.1097/PHM.0000000000001530
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: The Down Side of Prone Positioning: The Case of a Coronavirus 2019 Survivor. [Abstract]: The coronavirus 2019 pandemic has resulted in a surge of patients with acute respiratory distress syndrome. Prone positioning may be used in such patients to optimize oxygenation. Severe infections may leave survivors with...
32,301,631
AJR Am J Roentgenol
Lung Base Findings of Coronavirus Disease (COVID-19) on Abdominal CT in Patients With Predominant Gastrointestinal Symptoms.
OBJECTIVE. This series of patients presented to the emergency department (ED) with abdominal pain, without the respiratory symptoms typical of coronavirus disease (COVID-19), and the abdominal radiologist was the first to suggest COVID-19 infection because of findings in the lung bases on CT of the abdomen. CONCLUSION....
covid-19;sars-cov-2;abdominal ct;coronavirus;imaging findings;lung bases
Case Reports;Journal Article
Siegel, Avielle;Chang, Paul J;Jarou, Zachary J;Paushter, David M;Harmath, Carla B;Arevalo, J Ben;Dachman, Abraham
10.2214/AJR.20.23232
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Lung Base Findings of Coronavirus Disease (COVID-19) on Abdominal CT in Patients With Predominant Gastrointestinal Symptoms. [Abstract]: OBJECTIVE. This series of patients presented to the emergency department (ED) with abdominal pain, without the respiratory symptoms typical of coronavirus disease (COVID-19),...
33,036,445
J Clin Med
COVID-19 Triage and Test Center: Safety, Feasibility, and Outcomes of Low-Threshold Testing.
This prospective observational study evaluated the safety and feasibility of a low threshold testing process in a Triage and Test Center (TTC) during the early course of the coronavirus disease 19 (COVID-19) pandemic. In addition, we aimed to identify clinical predictors for a positive severe acute respiratory syndrome...
covid-19;sars-cov-2;triage and test center;disposition;drive-thru testing;resource allocation;symptoms
Journal Article
Mansella, Gregory;Rueegg, Marco;Widmer, Andreas F;Tschudin-Sutter, Sarah;Battegay, Manuel;Hoff, Julia;Sogaard, Kirstine K;Egli, Adrian;Stieltjes, Bram;Leuzinger, Karoline;Hirsch, Hans H;Meienberg, Andrea;Burkard, Thilo;Mayr, Michael;Bingisser, Roland;Nickel, Christian H
10.3390/jcm9103217
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: COVID-19 Triage and Test Center: Safety, Feasibility, and Outcomes of Low-Threshold Testing. [Abstract]: This prospective observational study evaluated the safety and feasibility of a low threshold testing process in a Triage and Test Center (TTC) during the early course of the coronavirus disease 19 (COVID-19...
32,483,500
Cureus
Refractory Acute Respiratory Distress Syndrome Secondary to COVID-19 Successfully Extubated to Average Volume-assured Pressure Support Non-invasive Ventilator.
Coronavirus disease 2019 (COVID-19) is a respiratory illness caused by the highly infectious novel SARS-CoV-2 coronavirus spread by droplet transmission. Consequently, the use of respiratory devices that may potentially promote aerosolization like non-invasive positive pressure ventilation (NIPPV) for diseases such as ...
avaps;covid 19;critical illness myopathy;non-invasive mechanical ventilation;pulmonary hypertension;sars-cov-2;worsening obstructive sleep apnea (osa)
Case Reports
Mittal, Abhinav;Forte, Michael;Leonard, Rachel;Sangani, Rahul;Sharma, Sunil
10.7759/cureus.7849
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Refractory Acute Respiratory Distress Syndrome Secondary to COVID-19 Successfully Extubated to Average Volume-assured Pressure Support Non-invasive Ventilator. [Abstract]: Coronavirus disease 2019 (COVID-19) is a respiratory illness caused by the highly infectious novel SARS-CoV-2 coronavirus spread by droplet...
32,959,627
Monaldi Arch Chest Dis
Telemedicine during COVID-19: a survey of Health Care Professionals' perceptions.
The National Health Service (NHS) has rapidly adopted telemedicine solutions as an alternative to face-to-face consultations during the COVID-19 pandemic. The majority of HCPs (Healthcare Professionals) were unfamiliar with Telemedicine prior to the current pandemic. Remote consultation is expected to continue for the ...
Journal Article
Elawady, Abdula;Khalil, Ahmed;Assaf, Omar;Toure, Samirah;Cassidy, Christopher
10.4081/monaldi.2020.1528
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Telemedicine during COVID-19: a survey of Health Care Professionals' perceptions. [Abstract]: The National Health Service (NHS) has rapidly adopted telemedicine solutions as an alternative to face-to-face consultations during the COVID-19 pandemic. The majority of HCPs (Healthcare Professionals) were unfamilia...
32,775,112
Cureus
Dermatological Manifestations in Patients With SARS-CoV-2: A Systematic Review.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been initially defined as a disease of the respiratory tract; however, with the increasing number of patients and announcing that the virus became a pandemic, new systemic clinical manifestations are observed, including dermatological manifestations. Howe...
covid 19;dermatological;manifestations;sars-cov-2;symptoms
Journal Article;Review
Almutairi, Abdulelah;Alfaleh, Mohammed;Alasheikh, Muath
10.7759/cureus.9446
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Dermatological Manifestations in Patients With SARS-CoV-2: A Systematic Review. [Abstract]: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been initially defined as a disease of the respiratory tract; however, with the increasing number of patients and announcing that the virus became a pande...
32,614,178
ACS Chem Neurosci
Pulmonary Edema in COVID19-A Neural Hypothesis.
In COVID-19, lung manifestations present as a slowly evolving pneumonia with insidious early onset interstitial pulmonary edema that undergoes acute exacerbation in the late stages and microvascular thrombosis. Currently, these manifestations are considered to be only consequences of pulmonary SARS-CoV-2 virus infectio...
brain trigger zones;covid-19;catecholamine storm;microvascular clotting;neurogenic pulmonary edema;nucleus tractus solitarius
Journal Article
U R, Anoop;Verma, Kavita
10.1021/acschemneuro.0c00370
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Pulmonary Edema in COVID19-A Neural Hypothesis. [Abstract]: In COVID-19, lung manifestations present as a slowly evolving pneumonia with insidious early onset interstitial pulmonary edema that undergoes acute exacerbation in the late stages and microvascular thrombosis. Currently, these manifestations are cons...
32,600,881
Surgery
General surgery chief residents' perspective on surgical education during the coronavirus disease 2019 (COVID-19) pandemic.
BACKGROUND: The coronavirus disease 2019 pandemic has negatively affected the training of general surgery chief residents during the last trimester of their residency. Our goal was to evaluate the educational concerns of graduating general surgery chief residents during the coronavirus disease 2019 pandemic. METHODS: A...
Journal Article
Zheng, Jian;Hundeyin, Mautin;He, Katherine;Sachs, Teviah;Hess, Donald T;Whang, Edward;Kristo, Gentian
10.1016/j.surg.2020.06.003
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: General surgery chief residents' perspective on surgical education during the coronavirus disease 2019 (COVID-19) pandemic. [Abstract]: BACKGROUND: The coronavirus disease 2019 pandemic has negatively affected the training of general surgery chief residents during the last trimester of their residency. Our goa...
32,308,221
Mo Med
Imported Infections in Rural Mid-West United States - A Report from a Tertiary Care Center.
Background: There is lack of specific data on imported infections in the mid-west United States (U.S.). Methods: Retrospective data on demographic and geographic data of imported infections seen by the infectious diseases clinics and consultation service from 2001-2018 was collected. Results: Of the 64 infections, tube...
Journal Article
Meyer, Amy;Regunath, Hariharan;Rojas-Moreno, Christian;Salzer, William;Christensen, Gordon
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Imported Infections in Rural Mid-West United States - A Report from a Tertiary Care Center. [Abstract]: Background: There is lack of specific data on imported infections in the mid-west United States (U.S.). Methods: Retrospective data on demographic and geographic data of imported infections seen by the infec...
32,792,262
Semin Perinatol
The clinical course of COVID in pregnancy.
The 2019 novel coronavirus disease (COVID-19) pandemic poses unique challenges to the medical community as the optimal treatment has not been determined and is often at the discretion of institutional guidelines. Pregnancy has previously been described as a high-risk state in the context of infectious diseases, given a...
Journal Article;Review
Syeda, Sbaa;Baptiste, Caitlin;Breslin, Noelle;Gyamfi-Bannerman, Cynthia;Miller, Russell
10.1016/j.semperi.2020.151284
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: The clinical course of COVID in pregnancy. [Abstract]: The 2019 novel coronavirus disease (COVID-19) pandemic poses unique challenges to the medical community as the optimal treatment has not been determined and is often at the discretion of institutional guidelines. Pregnancy has previously been described as ...
32,338,347
Indian J Pediatr
COVID-19 in Children: Clinical Approach and Management.
COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a major public health crisis threatening humanity at this point in time. Transmission of the infection occurs by inhalation of infected droplets or direct contact with soiled surfaces and fomites. It should be suspected in all s...
ards;acute lung injury;acute respiratory distress syndrome;covid-19;hydroxychloroquine;lopinavir;multiorgan dysfunction;ritonavir;sars-cov-2;severe pneumonia
Journal Article;Review
Sankar, Jhuma;Dhochak, Nitin;Kabra, S K;Lodha, Rakesh
10.1007/s12098-020-03292-1
[ 1, 1, 1, 0, 1, 0, 0 ]
[Title]: COVID-19 in Children: Clinical Approach and Management. [Abstract]: COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a major public health crisis threatening humanity at this point in time. Transmission of the infection occurs by inhalation of infected droplets or dir...
32,404,896
Spinal Cord Ser Cases
Clinical features of coronavirus disease 2019 (COVID-19) in a cohort of patients with disability due to spinal cord injury.
STUDY DESIGN: Cohort study of patients with spinal cord injury (SCI). OBJECTIVES: To describe the clinical and analytical features of a coronavirus disease 2019 (Covid-19) infected cohort with SCI to enable accurate diagnosis and to outline prevention measures. SETTING: This study was conducted at the National Hospital...
Journal Article
Rodriguez-Cola, Miguel;Jimenez-Velasco, Irena;Gutierrez-Henares, Francisco;Lopez-Dolado, Elisa;Gambarrutta-Malfatti, Claudia;Vargas-Baquero, Eduardo;Gil-Agudo, Angel
10.1038/s41394-020-0288-3
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical features of coronavirus disease 2019 (COVID-19) in a cohort of patients with disability due to spinal cord injury. [Abstract]: STUDY DESIGN: Cohort study of patients with spinal cord injury (SCI). OBJECTIVES: To describe the clinical and analytical features of a coronavirus disease 2019 (Covid-19) inf...
32,780,855
QJM
Staying safe while waiting for the vaccine: what we need to do.
Societies are organizing themselves to keep the COVID-19 virus at bay for the foreseeable future. The World Health Organization (WHO) has proposed that every country implement a comprehensive set of measures to prevent infection, detect cases, interrupt transmission, control clusters, suppress outbreaks and reduce mort...
Journal Article
Nabarro, D;Atkinson, J
10.1093/qjmed/hcaa244
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Staying safe while waiting for the vaccine: what we need to do. [Abstract]: Societies are organizing themselves to keep the COVID-19 virus at bay for the foreseeable future. The World Health Organization (WHO) has proposed that every country implement a comprehensive set of measures to prevent infection, detec...
33,052,008
Appl Psychol Health Well Being
Adherence to the Physical Distancing Measures during the COVID-19 Pandemic: A HAPA-Based Perspective.
BACKGROUND: The COVID-19 pandemic requires massive and rapid behavior change. The Health Action Process Approach (HAPA) describes personal determinants that play a key role in behavior change. This study investigated whether these determinants are associated with adherence to physical distancing measures to prevent the...
covid-19;hapa;physical distancing;psychosocial well-being;social support
Journal Article;Research Support, Non-U.S. Gov't
Beeckman, Melanie;De Paepe, Annick;Van Alboom, Maite;Maes, Sarah;Wauters, Aline;Baert, Fleur;Kissi, Ama;Veirman, Elke;Van Ryckeghem, Dimitri M L;Poppe, Louise
10.1111/aphw.12242
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Adherence to the Physical Distancing Measures during the COVID-19 Pandemic: A HAPA-Based Perspective. [Abstract]: BACKGROUND: The COVID-19 pandemic requires massive and rapid behavior change. The Health Action Process Approach (HAPA) describes personal determinants that play a key role in behavior change. This...
32,525,765
Emerg Microbes Infect
Genetic cluster analysis of SARS-CoV-2 and the identification of those responsible for the major outbreaks in various countries.
A newly emerged coronavirus, SARS-CoV-2, caused severe pneumonia outbreaks in China in December 2019 and has since spread to various countries around the world. To trace the evolution route and probe the transmission dynamics of this virus, we performed phylodynamic analysis of 247 high quality genomic sequences availa...
covid-19;sars-cov-2;phylodynamic analysis;super-spreader;transmission
Journal Article
Yang, Xuemei;Dong, Ning;Chan, Edward Wai-Chi;Chen, Sheng
10.1080/22221751.2020.1773745
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Genetic cluster analysis of SARS-CoV-2 and the identification of those responsible for the major outbreaks in various countries. [Abstract]: A newly emerged coronavirus, SARS-CoV-2, caused severe pneumonia outbreaks in China in December 2019 and has since spread to various countries around the world. To trace ...
32,585,284
Int J Infect Dis
Therapeutic plasma exchange in adults with severe COVID-19 infection.
OBJECTIVE: To evaluate the therapeutic use of plasma exchange in COVID-19 patients compared to controls. METHODS: A case series of critically ill adult men and non-pregnant women, >/=18 years of age, with laboratory-confirmed COVID-19, was studied at the Royal Hospital, Oman, from April 17 to May 11, 2020. Therapeutic ...
covid-19 infection;cytokine release syndrome;plasma exchange;pneumonia;sars-cov-2;severe acute respiratory distress syndrome
Journal Article
Khamis, Faryal;Al-Zakwani, Ibrahim;Al Hashmi, Sabria;Al Dowaiki, Samata;Al Bahrani, Maher;Pandak, Nenad;Al Khalili, Huda;Memish, Ziad
10.1016/j.ijid.2020.06.064
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Therapeutic plasma exchange in adults with severe COVID-19 infection. [Abstract]: OBJECTIVE: To evaluate the therapeutic use of plasma exchange in COVID-19 patients compared to controls. METHODS: A case series of critically ill adult men and non-pregnant women, >/=18 years of age, with laboratory-confirmed COV...
32,837,739
Saf Health Work
Infection Risks Faced by Public Health Laboratory Services Teams When Handling Specimens Associated With Coronavirus Disease 2019 (COVID-19).
Infection risks of handling specimens associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by public health laboratory services teams were assessed to scrutinize the potential hazards arising from the work procedures. Through risk assessments of all work sequences, laboratory equipment, and work...
covid-19;hand hygiene;laboratory workers;occupational safety;risk assessment
Journal Article
Wong, Chun-Kwan;Tsang, Dominic N-C;Chan, Rickjason C-W;Lam, Edman T-K;Jong, Kwok-Kwan
10.1016/j.shaw.2020.07.001
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Infection Risks Faced by Public Health Laboratory Services Teams When Handling Specimens Associated With Coronavirus Disease 2019 (COVID-19). [Abstract]: Infection risks of handling specimens associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by public health laboratory services teams...
32,720,031
Int Urol Nephrol
The kidney, COVID-19, and the chemokine network: an intriguing trio.
On December 30th 2019, some patients with pneumonia of unknown etiology were reported in the Program for Monitoring Emerging Diseases (ProMED), a program run by the International Society for Infectious Diseases (ISID), hypothesized to be related to subjects who had had contact with the seafood market in Wuhan, China. C...
2019-ncov;acute kidney injury;chemokines;coronavirus;kidney;sars-cov-2;urology
Journal Article;Review
Taverna, Gianluigi;Di Francesco, Simona;Borroni, Elena Monica;Yiu, Daniel;Toniato, Elena;Milanesi, Samantha;Chiriva-Internati, Maurizio;Bresalier, Robert S;Zanoni, Matteo;Vota, Paolo;Maffei, Davide;Justich, Matteo;Grizzi, Fabio
10.1007/s11255-020-02579-8
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: The kidney, COVID-19, and the chemokine network: an intriguing trio. [Abstract]: On December 30th 2019, some patients with pneumonia of unknown etiology were reported in the Program for Monitoring Emerging Diseases (ProMED), a program run by the International Society for Infectious Diseases (ISID), hypothesize...
32,811,354
Int J Vitam Nutr Res
Vitamin D can be effective on the prevention of COVID-19 complications: A narrative review on molecular aspects.
The widespread COVID-19 pandemic has been, currently, converted to a catastrophic human health challenge. Vitamin D (VD) and its metabolites have been used as a palliative treatment for chronic inflammatory and infectious diseases from ancient times. In the current study, some molecular aspects of the potential effects...
covid-19;calcitriol;coronavirus;vitamin d;molecular aspects
Journal Article
Shiravi, Amir-Abbas;Saadatkish, Milad;Abdollahi, Zeinab;Miar, Paniz;Khanahmad, Hossein;Zeinalian, Mehrdad
10.1024/0300-9831/a000676
[ 1, 0, 1, 1, 0, 0, 0 ]
[Title]: Vitamin D can be effective on the prevention of COVID-19 complications: A narrative review on molecular aspects. [Abstract]: The widespread COVID-19 pandemic has been, currently, converted to a catastrophic human health challenge. Vitamin D (VD) and its metabolites have been used as a palliative treatment for ...
32,854,391
Vaccines (Basel)
Current Clinical Trials Protocols and the Global Effort for Immunization against SARS-CoV-2.
Coronavirus disease 2019 (COVID-19) is the biggest health challenge of the 21st century, affecting millions of people globally. The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has ignited an unprecedented effort from the scientific community in the development of new vaccines on different p...
covid-19;d);sars-cov-2;immunization;research and development (r&vaccine
Journal Article;Review
Rego, Gabriel N A;Nucci, Mariana P;Alves, Arielly H;Oliveira, Fernando A;Marti, Luciana C;Nucci, Leopoldo P;Mamani, Javier B;Gamarra, Lionel F
10.3390/vaccines8030474
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Current Clinical Trials Protocols and the Global Effort for Immunization against SARS-CoV-2. [Abstract]: Coronavirus disease 2019 (COVID-19) is the biggest health challenge of the 21st century, affecting millions of people globally. The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) h...
32,790,661
MMWR Morb Mortal Wkly Rep
Transmission of SARS-CoV-2 Involving Residents Receiving Dialysis in a Nursing Home - Maryland, April 2020.
SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), can spread rapidly in nursing homes once it is introduced (1,2). To prevent outbreaks, more data are needed to identify sources of introduction and means of transmission within nursing homes. Nursing home residents who receive hemodialysis (dialysis...
Journal Article
Bigelow, Benjamin F;Tang, Olive;Toci, Gregory R;Stracker, Norberth;Sheikh, Fatima;Jacobs Slifka, Kara M;Novosad, Shannon A;Jernigan, John A;Reddy, Sujan C;Katz, Morgan J
10.15585/mmwr.mm6932e4
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Transmission of SARS-CoV-2 Involving Residents Receiving Dialysis in a Nursing Home - Maryland, April 2020. [Abstract]: SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), can spread rapidly in nursing homes once it is introduced (1,2). To prevent outbreaks, more data are needed to identify ...
32,803,688
Daru
The application of direct viral cytopathic hypothesis to design drug trials in the battle against COVID-19.
COVID-19 has caused many deaths worldwide. Systemic complications alongside coagulopathy, and ARDS account for the majority of COVID-19 mortalities. The pathogenesis of the disease can be explained by two theories of direct viral cytopathy and systemic inflammatory cascade of events. ACE-2 is shown to be the cellular h...
coronavirus disease of 2019 (covid-19);direct viral cytopathy;potential therapies
Letter
Ashraf, Mohammad Ali;Sherafat, Alireza;Pourdast, Alieh;Nazemi, Pershang;Mohraz, Minoo
10.1007/s40199-020-00368-3
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: The application of direct viral cytopathic hypothesis to design drug trials in the battle against COVID-19. [Abstract]: COVID-19 has caused many deaths worldwide. Systemic complications alongside coagulopathy, and ARDS account for the majority of COVID-19 mortalities. The pathogenesis of the disease can be exp...
32,259,322
Oncologist
Clinical Characteristics of COVID-19 After Gynecologic Oncology Surgery in Three Women: A Retrospective Review of Medical Records.
From a large medical center in Wuhan, the epicenter of the 2019 novel coronavirus disease (COVID-19), we report clinical features and prognosis for three women diagnosed with COVID-19 after gynecologic oncology surgery and hospitalized in January 2020. The incidence of COVID-19 was 0.77% (3 of 389) of total hospitaliza...
Journal Article
Yang, Shouhua;Zhang, Yuan;Cai, Jing;Wang, Zehua
10.1634/theoncologist.2020-0157
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Clinical Characteristics of COVID-19 After Gynecologic Oncology Surgery in Three Women: A Retrospective Review of Medical Records. [Abstract]: From a large medical center in Wuhan, the epicenter of the 2019 novel coronavirus disease (COVID-19), we report clinical features and prognosis for three women diagnose...
32,763,313
Antiviral Res
Remdesivir triphosphate can efficiently inhibit the RNA-dependent RNA polymerase from various flaviviruses.
Remdesivir was shown to inhibit RNA-dependent RNA-polymerases (RdRp) from distinct viral families such as from Filoviridae (Ebola) and Coronaviridae (SARS-CoV, SARS-CoV-2, MERS). In this study, we tested the ability of remdesivir to inhibit RdRps from the Flaviviridae family. Instead of remdesivir, we used the active s...
flavivirus;inhibitor;rna-dependent rna polymerase;remdesivir
Journal Article;Research Support, Non-U.S. Gov't
Konkolova, Eva;Dejmek, Milan;Hrebabecky, Hubert;Sala, Michal;Boserle, Jiri;Nencka, Radim;Boura, Evzen
10.1016/j.antiviral.2020.104899
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Remdesivir triphosphate can efficiently inhibit the RNA-dependent RNA polymerase from various flaviviruses. [Abstract]: Remdesivir was shown to inhibit RNA-dependent RNA-polymerases (RdRp) from distinct viral families such as from Filoviridae (Ebola) and Coronaviridae (SARS-CoV, SARS-CoV-2, MERS). In this stud...
32,702,590
J Mol Graph Model
Intermolecular interaction among Remdesivir, RNA and RNA-dependent RNA polymerase of SARS-CoV-2 analyzed by fragment molecular orbital calculation.
COVID-19, a disease caused by a new strain of coronavirus (SARS-CoV-2) originating from Wuhan, China, has now spread around the world, triggering a global pandemic, leaving the public eagerly awaiting the development of a specific medicine and vaccine. In response, aggressive efforts are underway around the world to ov...
coronaviruses;fragment molecular orbital method;interaction analysis;rna dependent rna polymerase;remdesivir;sars-cov-2;template-primer rna
Journal Article;Research Support, Non-U.S. Gov't
Kato, Koichiro;Honma, Teruki;Fukuzawa, Kaori
10.1016/j.jmgm.2020.107695
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Intermolecular interaction among Remdesivir, RNA and RNA-dependent RNA polymerase of SARS-CoV-2 analyzed by fragment molecular orbital calculation. [Abstract]: COVID-19, a disease caused by a new strain of coronavirus (SARS-CoV-2) originating from Wuhan, China, has now spread around the world, triggering a glo...
33,078,471
J Paediatr Child Health
Drive-through transcutaneous bilirubin screening for neonatal jaundice: A safe and efficient system during the COVID-19 pandemic.
The coronavirus disease 2019 (COVID-19) cases was on an increasing trend, including in Malaysia. The Malaysian Ministry of Health had implemented a range of measures, such as the use of masks and social distancing, to reduce the risk of transmission. Traditionally, newborns are evaluated for neonatal jaundice using vis...
Journal Article
Chua, Bee-Sim;Song, Li-Herng;Chang, Chee-Tao;Lim, Xin-Jie;Nachiappan, Jeyaseelan
10.1111/jpc.15226
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Drive-through transcutaneous bilirubin screening for neonatal jaundice: A safe and efficient system during the COVID-19 pandemic. [Abstract]: The coronavirus disease 2019 (COVID-19) cases was on an increasing trend, including in Malaysia. The Malaysian Ministry of Health had implemented a range of measures, su...
32,497,341
J Card Surg
Acute complicated type B aortic dissection during the New York City COVID-19 surge.
The impact of the coronavirus disease 2019 (COVID-19) pandemic in New York City (NYC) is dramatic. COVID-19 cases surged, hospitals expanded to meet capacity, and NYC remains the global epicenter of this pandemic. During this unprecedented time, a young woman with known Marfan syndrome presented with an acute complicat...
covid-19;petticoat;acute complicated type b aortic dissection
Case Reports
Ikeda, Shinichiro;Shih, Michael;Rhee, Robert Y;Youdelman, Benjamin A
10.1111/jocs.14678
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Acute complicated type B aortic dissection during the New York City COVID-19 surge. [Abstract]: The impact of the coronavirus disease 2019 (COVID-19) pandemic in New York City (NYC) is dramatic. COVID-19 cases surged, hospitals expanded to meet capacity, and NYC remains the global epicenter of this pandemic. D...
32,592,160
J Community Health
Analysis of Risk Perceptions and Related Factors Concerning COVID-19 Epidemic in Chongqing, China.
OBJECTIVE: To assess perceptions of risk and related factors concerning COVID-19 epidemic among residents in Chongqing city, China. METHODS: With convenience sampling, a web questionnaire survey was conducted among 476 residents living in Chongqing on February 13rd to 14th in 2020, when citizens just started to get bac...
covid-19;community;media information;residents;risk perception
Journal Article;Research Support, Non-U.S. Gov't
He, Shan;Chen, Siyu;Kong, Lingna;Liu, Weiwei
10.1007/s10900-020-00870-4
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Analysis of Risk Perceptions and Related Factors Concerning COVID-19 Epidemic in Chongqing, China. [Abstract]: OBJECTIVE: To assess perceptions of risk and related factors concerning COVID-19 epidemic among residents in Chongqing city, China. METHODS: With convenience sampling, a web questionnaire survey was c...
32,723,108
J Dermatolog Treat
The efficacy of rituximab in patients with mucous membrane pemphigoid.
OBJECTIVE: Mucous membrane pemphigoid (MMP) is an autoimmune blistering disorder with tendency to scarring. Long term immunosuppressive treatment may be required to minimize the consequences of the disease. METHODS: In this retrospective study, we investigated the efficacy of rituximab (RTX) in MMP patients and compare...
covid-19;ivig;mucous membrane pemphigoid;rituximab;therapy
Journal Article
Amir Dastmalchi, Delara;Moslemkhani, Solmaz;Bayat, Maryam;Balighi, Kamran;Abedini, Robabeh;Mahmoudi, Hamidreza;Daneshpazhooh, Maryam
10.1080/09546634.2020.1801974
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: The efficacy of rituximab in patients with mucous membrane pemphigoid. [Abstract]: OBJECTIVE: Mucous membrane pemphigoid (MMP) is an autoimmune blistering disorder with tendency to scarring. Long term immunosuppressive treatment may be required to minimize the consequences of the disease. METHODS: In this retr...
32,775,789
Adv Radiat Oncol
Computed Tomography in Radiation Oncology During the Coronavirus Disease 2019 Pandemic.
During the coronavirus disease 2019 (COVID-19) pandemic, cancer centers must implement effective measures to protect patients and staff from infection with the novel coronavirus. A critical component of this effort is the timely identification of patients undergoing treatment who have COVID-19. Limitations on testing m...
Journal Article
Marcus, David M;Weathers, William M;Rossi, Peter J
10.1016/j.adro.2020.06.003
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Computed Tomography in Radiation Oncology During the Coronavirus Disease 2019 Pandemic. [Abstract]: During the coronavirus disease 2019 (COVID-19) pandemic, cancer centers must implement effective measures to protect patients and staff from infection with the novel coronavirus. A critical component of this eff...
32,530,531
J Med Virol
Are coinfections with COVID-19 and influenza low or underreported? An observational study examining current published literature including three new unpublished cases.
As the coronavirus disease-2019 (COVID-19) pandemic continues, one major point of uncertainty is the impact this novel pathogen will have during the upcoming 2020 to 2021 flu season. While the influenza virus is a known contributor to human morbidity and mortality, the question of how a coinfection between COVID-19 and...
covid-19;coinfection;influenza virus
Journal Article;Review
Antony, Suresh J;Almaghlouth, Nouf K;Heydemann, Emily L
10.1002/jmv.26167
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Are coinfections with COVID-19 and influenza low or underreported? An observational study examining current published literature including three new unpublished cases. [Abstract]: As the coronavirus disease-2019 (COVID-19) pandemic continues, one major point of uncertainty is the impact this novel pathogen wil...
32,425,321
Am J Emerg Med
Neurologic complications of COVID-19.
BACKGROUND: Much of the focus regarding the global pandemic of coronavirus disease of 2019 (COVID-19) has been on the cardiovascular, pulmonary, and hematologic complications. However, neurologic complications have arisen as an increasingly recognized area of morbidity and mortality. OBJECTIVE: This brief report summar...
covid-19;cerebrovascular disease;coronavirus;encephalopathy;hlh;infectious disease;neurologic
Journal Article;Review
Bridwell, Rachel;Long, Brit;Gottlieb, Michael
10.1016/j.ajem.2020.05.024
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Neurologic complications of COVID-19. [Abstract]: BACKGROUND: Much of the focus regarding the global pandemic of coronavirus disease of 2019 (COVID-19) has been on the cardiovascular, pulmonary, and hematologic complications. However, neurologic complications have arisen as an increasingly recognized area of m...