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32,696,812
Rev Soc Bras Med Trop
Computed tomography findings in a Brazilian cohort of 48 patients with pneumonia due to coronavirus disease.
INTRODUCTION: This study was conducted to retrospectively review chest computed tomography (CT) findings in a Brazilian cohort of patients with pneumonia caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). METHODS: Chest CT scans of 78 patients with confirmed coronavirus disease (COVID-19), obta...
Journal Article
Werberich, Gabriel Madeira;Marchiori, Edson;Barreto, Miriam Menna;Rodrigues, Rosana Souza
10.1590/0037-8682-0405-2020
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Computed tomography findings in a Brazilian cohort of 48 patients with pneumonia due to coronavirus disease. [Abstract]: INTRODUCTION: This study was conducted to retrospectively review chest computed tomography (CT) findings in a Brazilian cohort of patients with pneumonia caused by the severe acute respirato...
32,591,388
Appl Environ Microbiol
Persistence of Bacteriophage Phi 6 on Porous and Nonporous Surfaces and the Potential for Its Use as an Ebola Virus or Coronavirus Surrogate.
The infection of health care workers during the 2013 to 2016 Ebola outbreak raised concerns about fomite transmission. In the wake of the coronavirus disease 2019 (COVID-19) pandemic, investigations are ongoing to determine the role of fomites in coronavirus transmission as well. The bacteriophage phi 6 has a phospholi...
ebola virus;coronavirus;enveloped viruses;environmental microbiology;health care transmission;phi 6 bacteriophage;public health;surface persistence;surrogate;virology
Journal Article
Whitworth, Carrie;Mu, Yi;Houston, Hollis;Martinez-Smith, Marla;Noble-Wang, Judith;Coulliette-Salmond, Angela;Rose, Laura
10.1128/AEM.01482-20
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Persistence of Bacteriophage Phi 6 on Porous and Nonporous Surfaces and the Potential for Its Use as an Ebola Virus or Coronavirus Surrogate. [Abstract]: The infection of health care workers during the 2013 to 2016 Ebola outbreak raised concerns about fomite transmission. In the wake of the coronavirus disease...
32,563,134
Forensic Sci Int
Impact of Covid-19 lockdown on characteristics of autopsy cases in Greece. Comparison between 2019 and 2020.
In order to reduce transmission of COVID-19, social distancing measures were proposed, including spatial distancing (2m distance), or even generalized lockdown. Main concern was to prevent overwhelming of the healthcare systems, mainly of the intensive care units (ICUs) by decreasing the spreading of the disease. In Gr...
covid-19;forensic medicine;greece;lockdown;mortality;sars-cov-2
Comparative Study;Journal Article
Sakelliadis, Emmanouil I;Katsos, Konstantinos D;Zouzia, Evmorfili I;Spiliopoulou, Chara A;Tsiodras, Sotirios
10.1016/j.forsciint.2020.110365
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Impact of Covid-19 lockdown on characteristics of autopsy cases in Greece. Comparison between 2019 and 2020. [Abstract]: In order to reduce transmission of COVID-19, social distancing measures were proposed, including spatial distancing (2m distance), or even generalized lockdown. Main concern was to prevent o...
32,771,560
J Allergy Clin Immunol
Asthma among hospitalized patients with COVID-19 and related outcomes.
BACKGROUND: Several underlying conditions have been associated with severe acute respiratory syndrome coronavirus 2 illness, but it remains unclear whether underlying asthma is associated with worse coronavirus disease 2019 (COVID-19) outcomes. OBJECTIVE: Given the high prevalence of asthma in the New York City area, o...
new york city;sars-cov-2;coronavirus;respiratory disease
Journal Article
Lovinsky-Desir, Stephanie;Deshpande, Deepti R;De, Aliva;Murray, Laurie;Stingone, Jeanette A;Chan, Angela;Patel, Neha;Rai, Nooralam;DiMango, Emily;Milner, Joshua;Kattan, Meyer
10.1016/j.jaci.2020.07.026
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Asthma among hospitalized patients with COVID-19 and related outcomes. [Abstract]: BACKGROUND: Several underlying conditions have been associated with severe acute respiratory syndrome coronavirus 2 illness, but it remains unclear whether underlying asthma is associated with worse coronavirus disease 2019 (COV...
32,096,396
Zhonghua Zhong Liu Za Zhi
[Surgical treatment strategy for digestive system malignancies during the outbreak of COVID-19].
The outbreak of COVID-19 occurred in Wuhan, Hubei province of China, at the end of 2019, and spread rapidly across the country. After the outbreak of this disease, the overwhelming majority of cities have launched the "first level response" and the regular diagnosis and treatment of cancer patients are greatly affected...
covid-19;diagnosis and treatment;digestive system;neoplasms
Journal Article
Ma, F H;Hu, H T;Tian, Y T
10.3760/cma.j.cn112152-20200223-00117
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: [Surgical treatment strategy for digestive system malignancies during the outbreak of COVID-19]. [Abstract]: The outbreak of COVID-19 occurred in Wuhan, Hubei province of China, at the end of 2019, and spread rapidly across the country. After the outbreak of this disease, the overwhelming majority of cities ha...
32,360,793
Can J Cardiol
Ramping Up the Delivery of Cardiac Surgery During the COVID-19 Pandemic: A Guidance Statement From the Canadian Society of Cardiac Surgeons.
The coronavirus disease 2019 (COVID-19) has had a profound global effect. Its rapid transmissibility has forced whole countries to adopt strict measures to contain its spread. As part of necessary pandemic planning, most Canadian cardiac surgical programs have prioritized and delayed elective procedures in an effort to...
Journal Article
Hassan, Ansar;Arora, Rakesh C;Lother, Sylvain A;Adams, Corey;Bouchard, Denis;Cook, Richard;Gunning, Derek;Lamarche, Yoan;Malas, Tarek;Moon, Michael;Ouzounian, Maral;Rao, Vivek;Rubens, Fraser;Tremblay, Philippe;Whitlock, Richard;Moss, Emmanuel;Legare, Jean-Francois
10.1016/j.cjca.2020.04.030
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Ramping Up the Delivery of Cardiac Surgery During the COVID-19 Pandemic: A Guidance Statement From the Canadian Society of Cardiac Surgeons. [Abstract]: The coronavirus disease 2019 (COVID-19) has had a profound global effect. Its rapid transmissibility has forced whole countries to adopt strict measures to co...
32,853,434
Eur J Neurol
Cytokine release syndrome-associated encephalopathy in patients with COVID-19.
BACKGROUND AND PURPOSE: Neurological manifestations in coronavirus disease (COVID)-2019 may adversely affect clinical outcomes. Severe COVID-19 and uremia are risk factors for neurological complications. However, the lack of insight into their pathogenesis, particularly with respect to the role of the cytokine release ...
covid-19;corticosteroids;cytokine;encephalitis;intravenous immunoglobulins;kidney;neurological disorders
Case Reports;Journal Article
Perrin, P;Collongues, N;Baloglu, S;Bedo, D;Bassand, X;Lavaux, T;Gautier-Vargas, G;Keller, N;Kremer, S;Fafi-Kremer, S;Moulin, B;Benotmane, I;Caillard, S
10.1111/ene.14491
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Cytokine release syndrome-associated encephalopathy in patients with COVID-19. [Abstract]: BACKGROUND AND PURPOSE: Neurological manifestations in coronavirus disease (COVID)-2019 may adversely affect clinical outcomes. Severe COVID-19 and uremia are risk factors for neurological complications. However, the lac...
32,882,235
J Pediatr (Rio J)
Laboratory diagnosis of COVID-19.
OBJECTIVES: This was a non-systematic review of the literature on the laboratory diagnosis of COVID-19. DATA SOURCES: Searches in PubMed and Google Scholar for articles made available in 2020, using the terms "diagnosis" OR "diagnostic" OR "diagnostic tests" OR "tests" AND "COVID-19" OR "SARS-CoV-2" in the title. SUMMA...
covid-19;coronavirus;diagnosis;diagnostic techniques and procedures;diagnostic tests
Journal Article;Review
Goudouris, Ekaterini S
10.1016/j.jped.2020.08.001
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Laboratory diagnosis of COVID-19. [Abstract]: OBJECTIVES: This was a non-systematic review of the literature on the laboratory diagnosis of COVID-19. DATA SOURCES: Searches in PubMed and Google Scholar for articles made available in 2020, using the terms "diagnosis" OR "diagnostic" OR "diagnostic tests" OR "te...
32,517,353
J Clin Med
Silibinin and SARS-CoV-2: Dual Targeting of Host Cytokine Storm and Virus Replication Machinery for Clinical Management of COVID-19 Patients.
COVID-19, the illness caused by infection with the novel coronavirus SARS-CoV-2, is a rapidly spreading global pandemic in urgent need of effective treatments. Here we present a comprehensive examination of the host- and virus-targeted functions of the flavonolignan silibinin, a potential drug candidate against COVID-1...
il-6;jak;coronavirus;cytokine storm;remdesivir;senescence;stat3
Journal Article
Bosch-Barrera, Joaquim;Martin-Castillo, Begona;Buxo, Maria;Brunet, Joan;Encinar, Jose Antonio;Menendez, Javier A
10.3390/jcm9061770
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Silibinin and SARS-CoV-2: Dual Targeting of Host Cytokine Storm and Virus Replication Machinery for Clinical Management of COVID-19 Patients. [Abstract]: COVID-19, the illness caused by infection with the novel coronavirus SARS-CoV-2, is a rapidly spreading global pandemic in urgent need of effective treatment...
32,282,894
Ann Intern Med
Diagnostic Testing for Severe Acute Respiratory Syndrome-Related Coronavirus 2: A Narrative Review.
Diagnostic testing to identify persons infected with severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) infection is central to control the global pandemic of COVID-19 that began in late 2019. In a few countries, the use of diagnostic testing on a massive scale has been a cornerstone of successful con...
antibodies;antigens;covid-19;cells;infectious disease immunology;nucleic acids;prevention, policy, and public health;pulmonary diseases;research laboratories;upper respiratory tract infections
Journal Article;Research Support, Non-U.S. Gov't;Review
Cheng, Matthew P;Papenburg, Jesse;Desjardins, Michael;Kanjilal, Sanjat;Quach, Caroline;Libman, Michael;Dittrich, Sabine;Yansouni, Cedric P
10.7326/M20-1301
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Diagnostic Testing for Severe Acute Respiratory Syndrome-Related Coronavirus 2: A Narrative Review. [Abstract]: Diagnostic testing to identify persons infected with severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) infection is central to control the global pandemic of COVID-19 that began in...
32,710,652
Pediatr Pulmonol
Children and COVID-19: Microbiological and immunological insights.
Since its first description in China, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide being declared a pandemic by the World Health Organization. More than 10.3 million people have been infected and more than 506 000 people died. However, SARS-CoV-2 had a lower impact on the pediatric ...
covid-19;sars-cov-2;children;immunology;novel coronavirus
Journal Article;Review
Buonsenso, Danilo;Sali, Michela;Pata, Davide;De Rose, Cristina;Sanguinetti, Maurizio;Valentini, Piero;Delogu, Giovanni
10.1002/ppul.24978
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: Children and COVID-19: Microbiological and immunological insights. [Abstract]: Since its first description in China, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide being declared a pandemic by the World Health Organization. More than 10.3 million people have been infected and...
32,352,450
Rhinology
Sniffing out the evidence; It's now time for public health bodies recognize the link between COVID-19 and smell and taste disturbance.
Since the outbreak of the pandemic, anecdotal observations have been accumulating rapidly that sudden anosmia and dysgeusia are peculiar symptoms associated with the COVID-19 infection. Prof C. Hopkins, as President of British Rhinological Society, published a letter describing "the loss of sense of smell as a marker o...
Journal Article
Lechien, J R;Hopkins, C;Saussez, S
10.4193/Rhin20.159
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: Sniffing out the evidence; It's now time for public health bodies recognize the link between COVID-19 and smell and taste disturbance. [Abstract]: Since the outbreak of the pandemic, anecdotal observations have been accumulating rapidly that sudden anosmia and dysgeusia are peculiar symptoms associated with th...
32,330,308
Br J Haematol
COVID19 coagulopathy in Caucasian patients.
Although the pathophysiology underlying severe COVID19 remains poorly understood, accumulating data suggest that a lung-centric coagulopathy may play an important role. Elevated D-dimer levels which correlated inversely with overall survival were recently reported in Chinese cohort studies. Critically however, ethnicit...
covid19;d-dimer;coagulation parameter;novel coronavirus pneumonia
Journal Article
Fogarty, Helen;Townsend, Liam;Ni Cheallaigh, Cliona;Bergin, Colm;Martin-Loeches, Ignacio;Browne, Paul;Bacon, Christopher L;Gaule, Richard;Gillett, Alexander;Byrne, Mary;Ryan, Kevin;O'Connell, Niamh;O'Sullivan, Jamie M;Conlon, Niall;O'Donnell, James S
10.1111/bjh.16749
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: COVID19 coagulopathy in Caucasian patients. [Abstract]: Although the pathophysiology underlying severe COVID19 remains poorly understood, accumulating data suggest that a lung-centric coagulopathy may play an important role. Elevated D-dimer levels which correlated inversely with overall survival were recently...
32,450,049
Med Teach
Training disrupted: Practical tips for supporting competency-based medical education during the COVID-19 pandemic.
The COVID-19 pandemic has disrupted healthcare systems around the world, impacting how we deliver medical education. The normal day-to-day routines have been altered for a number of reasons, including changes to scheduled training rotations, physical distancing requirements, trainee redeployment, and heightened level o...
outcome-based;change;medicine;postgraduate;teaching and learning
Journal Article
Hall, Andrew K;Nousiainen, Markku T;Campisi, Paolo;Dagnone, J Damon;Frank, Jason R;Kroeker, Karen I;Brzezina, Stacey;Purdy, Eve;Oswald, Anna
10.1080/0142159X.2020.1766669
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Training disrupted: Practical tips for supporting competency-based medical education during the COVID-19 pandemic. [Abstract]: The COVID-19 pandemic has disrupted healthcare systems around the world, impacting how we deliver medical education. The normal day-to-day routines have been altered for a number of re...
32,750,974
IEEE J Biomed Health Inform
COVID-19 Optimizer Algorithm, Modeling and Controlling of Coronavirus Distribution Process.
The emergence of novel COVID-19 is causing an overload on public health sector and a high fatality rate. The key priority is to contain the epidemic and reduce the infection rate. It is imperative to stress on ensuring extreme social distancing of the entire population and hence slowing down the epidemic spread. So, th...
Evaluation Study;Journal Article
Hosseini, Eghbal;Ghafoor, Kayhan Zrar;Sadiq, Ali Safaa;Guizani, Mohsen;Emrouznejad, Ali
10.1109/JBHI.2020.3012487
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 Optimizer Algorithm, Modeling and Controlling of Coronavirus Distribution Process. [Abstract]: The emergence of novel COVID-19 is causing an overload on public health sector and a high fatality rate. The key priority is to contain the epidemic and reduce the infection rate. It is imperative to stress ...
32,970,541
Soc Work Public Health
COVID-19 in Nigeria: Knowledge and compliance with preventive measures.
The novel coronavirus pandemic has upended the world as we knew it and is a concern for governments globally. With cases still surging in different regions around the globe, the level of knowledge of COVID-19 and compliance with preventive measures still differ across cultural regions. Our study explored knowledge of C...
covid-19;community transmission;coronavirus;physical/social distancing;social work
Journal Article;Video-Audio Media
Nnama-Okechukwu, Chinwe U;Chukwu, Ngozi E;Nkechukwu, Chiamaka N
10.1080/19371918.2020.1806985
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 in Nigeria: Knowledge and compliance with preventive measures. [Abstract]: The novel coronavirus pandemic has upended the world as we knew it and is a concern for governments globally. With cases still surging in different regions around the globe, the level of knowledge of COVID-19 and compliance wit...
32,612,371
Infect Drug Resist
Knowledge, Attitude and Practice Towards COVID-19 Among Chronic Disease Patients at Addis Zemen Hospital, Northwest Ethiopia.
Purpose: The recent outbreak of coronavirus disease 2019 (COVID-19) is the worst global crisis after the Second World War. Since no successful treatment and vaccine have been reported, efforts to enhance the knowledge, attitudes, and practice of the public, especially the high-risk groups, are critical to manage COVID-...
covid-19;ethiopia;attitude;chronic disease patients;knowledge;practice
Journal Article
Akalu, Yonas;Ayelign, Birhanu;Molla, Meseret Derbew
10.2147/IDR.S258736
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Knowledge, Attitude and Practice Towards COVID-19 Among Chronic Disease Patients at Addis Zemen Hospital, Northwest Ethiopia. [Abstract]: Purpose: The recent outbreak of coronavirus disease 2019 (COVID-19) is the worst global crisis after the Second World War. Since no successful treatment and vaccine have bee...
32,496,240
Indian J Public Health
The global experience of digital health interventions in COVID-19 management.
Digital health interventions are globally playing a significant role to combat coronavirus disease 2019 (COVID-19), which is an infectious disease caused by Severe Acute Respiratory Syndrome coronavirus 2. Here, we present a very brief overview of the multifaceted digital interventions, globally, and in India, for main...
digital health management;it/ict applications for coronavirus disease 2019;digital management of pandemic
Journal Article;Review
Sarbadhikari, Sohini;Sarbadhikari, Suptendra Nath
10.4103/ijph.IJPH_457_20
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The global experience of digital health interventions in COVID-19 management. [Abstract]: Digital health interventions are globally playing a significant role to combat coronavirus disease 2019 (COVID-19), which is an infectious disease caused by Severe Acute Respiratory Syndrome coronavirus 2. Here, we presen...
33,004,002
BMC Nephrol
COVID-19 in patients undergoing chronic kidney replacement therapy and kidney transplant recipients in Scotland: findings and experience from the Scottish renal registry.
BACKGROUND: Infection with the severe acute respiratory coronavirus 2 (SARS-CoV-2) has led to a worldwide pandemic with coronavirus disease 2019 (COVID-19), the disease caused by SARS-CoV-2, overwhelming healthcare systems globally. Preliminary reports suggest a high incidence of infection and mortality with SARS-CoV-2...
covid-19;epidemiology;kidney replacement therapy;registry
Journal Article;Observational Study
Bell, Samira;Campbell, Jacqueline;McDonald, Jackie;O'Neill, Martin;Watters, Chrissie;Buck, Katharine;Cousland, Zoe;Findlay, Mark;Lone, Nazir I;Metcalfe, Wendy;Methven, Shona;Peel, Robert;Almond, Alison;Sanu, Vinod;Spalding, Elaine;Thomson, Peter C;Mark, Patrick B;Traynor, Jamie P
10.1186/s12882-020-02061-8
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 in patients undergoing chronic kidney replacement therapy and kidney transplant recipients in Scotland: findings and experience from the Scottish renal registry. [Abstract]: BACKGROUND: Infection with the severe acute respiratory coronavirus 2 (SARS-CoV-2) has led to a worldwide pandemic with coronavi...
32,306,166
Jpn J Radiol
The prevention and management of the coronavirus disease 2019 (COVID-19) outbreak in radiology departments in epidemic areas.
This review based on the actual results of epidemic prevention management in radiology departments in epidemic areas, and using designated hospital management methods, to summarize the radiology protection system. With the cooperation of the whole hospital and radiology department, a number of effective evaluation meth...
hospital management;novel coronavirus;pneumonia epidemic;prevention
Journal Article;Review
Deng, Ming
10.1007/s11604-020-00974-w
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The prevention and management of the coronavirus disease 2019 (COVID-19) outbreak in radiology departments in epidemic areas. [Abstract]: This review based on the actual results of epidemic prevention management in radiology departments in epidemic areas, and using designated hospital management methods, to su...
32,270,980
Am J Manag Care
Incorporating telemedicine as part of COVID-19 outbreak response systems.
Healthcare providers should revisit disaster response policies to incorporate telemedicine systems to address some of the unique challenges posed by infectious disease outbreaks such as coronavirus disease 2019 (COVID-19).
Journal Article
Rockwell, Kimberly Lovett;Gilroy, Alexis S
10.37765/ajmc.2020.42784
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Incorporating telemedicine as part of COVID-19 outbreak response systems. [Abstract]: Healthcare providers should revisit disaster response policies to incorporate telemedicine systems to address some of the unique challenges posed by infectious disease outbreaks such as coronavirus disease 2019 (COVID-19). [K...
32,992,409
Cell Biochem Funct
SARS-COV-2 (COVID-19): Cellular and biochemical properties and pharmacological insights into new therapeutic developments.
COVID-19 caused by SARS-COV-2 first appeared in the Wuhan City of China and began to spread rapidly among people. Rapid progression of the outbreak has led to a major global public health problem of a potentially fatal disease. On January 30, 2020, WHO declared the pandemic as the sixth public health emergency of the w...
ace2;covid-19;cardiovascular disease;pandemia;pharmacological agents;vaccine
Journal Article;Review
Parlakpinar, Hakan;Gunata, Mehmet
10.1002/cbf.3591
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: SARS-COV-2 (COVID-19): Cellular and biochemical properties and pharmacological insights into new therapeutic developments. [Abstract]: COVID-19 caused by SARS-COV-2 first appeared in the Wuhan City of China and began to spread rapidly among people. Rapid progression of the outbreak has led to a major global pu...
33,063,092
Biosci Rep
Immunotherapy of COVID-19 with poly (ADP-ribose) polymerase inhibitors: starting with nicotinamide.
COVID-19 induces a proinflammatory environment that is stronger in patients requiring intensive care. The cytokine components of this environment may determine efficacy or otherwise of glucocorticoid therapy. The immunity modulators, the aryl hydrocarbon receptor (AhR) and the nuclear NAD+-consuming enzyme poly (ADP-ri...
aryl hydrocarbon receptor;indoleamine 2,3-dioxygenase;kynurenine pathway;nicotinamide;poly (adp-ribose) polymerase;glucocorticoids
Journal Article;Review
Badawy, Abdulla A-B
10.1042/BSR20202856
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Immunotherapy of COVID-19 with poly (ADP-ribose) polymerase inhibitors: starting with nicotinamide. [Abstract]: COVID-19 induces a proinflammatory environment that is stronger in patients requiring intensive care. The cytokine components of this environment may determine efficacy or otherwise of glucocorticoid...
32,298,006
Head Neck
Care of immunocompromised patients with head and neck cancer during the COVID-19 pandemic: Two challenging and informative clinical cases.
BACKGROUND AND METHODS: There is an added level of complexity in the management of head and neck cancer patients with underlying immunosuppressive disorders during the COVID-19 pandemic. Head and neck oncologists are tasked with balancing the dual risks of cancer progression in the setting of impaired tumor immunity an...
covid-19;airway;head and neck cancer;immunosuppression;risk management
Case Reports;Journal Article
Civantos, Alyssa M;Carey, Ryan M;Lichtenstein, Gary R;Lukens, John N;Cohen, Roger B;Rassekh, Christopher H
10.1002/hed.26165
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Care of immunocompromised patients with head and neck cancer during the COVID-19 pandemic: Two challenging and informative clinical cases. [Abstract]: BACKGROUND AND METHODS: There is an added level of complexity in the management of head and neck cancer patients with underlying immunosuppressive disorders dur...
32,451,923
Drugs
The G-Quadruplex/Helicase World as a Potential Antiviral Approach Against COVID-19.
G-Quadruplexes (G4s) are non-canonical secondary structures formed within guanine-rich regions of DNA or RNA. G4 sequences/structures have been detected in human and in viral genomes, including Coronaviruses Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and SARS-CoV-2. Here, we outline the existing evidence ...
Journal Article
Panera, Nadia;Tozzi, Alberto Eugenio;Alisi, Anna
10.1007/s40265-020-01321-z
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: The G-Quadruplex/Helicase World as a Potential Antiviral Approach Against COVID-19. [Abstract]: G-Quadruplexes (G4s) are non-canonical secondary structures formed within guanine-rich regions of DNA or RNA. G4 sequences/structures have been detected in human and in viral genomes, including Coronaviruses Severe ...
32,841,850
Sleep Med
Management of sleep apnea in New York City during the COVID-19 pandemic.
BACKGROUND: With the onset of the COVID-19 outbreak there has been concern that patients with obstructive sleep apnea (OSA) who develop COVID-19 may be at risk of greater morbidity and mortality than patients without OSA. COVID-19 is associated with an increased mortality in the elderly and particularly those with obes...
covid-19;cpap;morbidity;mortality;new york;obstructive sleep apnea
Journal Article
Thorpy, Michael;Figuera-Losada, Mariana;Ahmed, Imran;Monderer, Renee;Petrisko, Monica;Martin, Chris;Akhtar, Jamal;Thorpy, Jacqueline;Haines, Carver
10.1016/j.sleep.2020.07.013
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Management of sleep apnea in New York City during the COVID-19 pandemic. [Abstract]: BACKGROUND: With the onset of the COVID-19 outbreak there has been concern that patients with obstructive sleep apnea (OSA) who develop COVID-19 may be at risk of greater morbidity and mortality than patients without OSA. COVI...
32,437,587
Eur J Immunol
COVID-19 vaccines: Knowing the unknown.
Vaccine development against SARS-CoV-2 has drawn attention around the globe due to the exploding pandemic. Although COVID-19 is caused by a new coronavirus, SARS-CoV-2, previous research on other coronavirus vaccines, such as FIPV, SARS, and MERS, has provided valuable information for the rapid development of COVID-19 ...
covid-19;sars-cov-2;vaccine
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Lv, Huibin;Wu, Nicholas C;Mok, Chris K P
10.1002/eji.202048663
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: COVID-19 vaccines: Knowing the unknown. [Abstract]: Vaccine development against SARS-CoV-2 has drawn attention around the globe due to the exploding pandemic. Although COVID-19 is caused by a new coronavirus, SARS-CoV-2, previous research on other coronavirus vaccines, such as FIPV, SARS, and MERS, has provide...
32,373,652
Mov Disord Clin Pract
Management of Advanced Therapies in Parkinson's Disease Patients in Times of Humanitarian Crisis: The COVID-19 Experience.
Background: Although the COVID-19 pandemic is affecting a relatively small proportion of the global population, its effects have already reached everyone. The pandemic has the potential to differentially disadvantage chronically ill patients, including those with Parkinson's disease (PD). The first health care reaction...
covid-19;parkinson's disease;sars-cov-2;advanced therapies;telemedicine
Journal Article;Review
Fasano, Alfonso;Antonini, Angelo;Katzenschlager, Regina;Krack, Paul;Odin, Per;Evans, Andrew H;Foltynie, Thomas;Volkmann, Jens;Merello, Marcelo
10.1002/mdc3.12965
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Management of Advanced Therapies in Parkinson's Disease Patients in Times of Humanitarian Crisis: The COVID-19 Experience. [Abstract]: Background: Although the COVID-19 pandemic is affecting a relatively small proportion of the global population, its effects have already reached everyone. The pandemic has the ...
32,500,322
Aesthetic Plast Surg
Securing Posterior Auricular Incision with Button Headbands in Prominent Ear Patients Wearing Surgical Masks for Self-protection in the Pandemic.
In this letter, we describe an attachment on conventional headbands recommended for the postoperative period in prominent ear patients to confidently wear surgical masks without disturbing the posterior auricular incision. LEVEL OF EVIDENCE V: This journal requires that authors assign a level of evidence to each articl...
aesthetic surgery;button headband;covid-19;pandemic;patient security;prominent ear;surgical mask
Letter;Review
Ozkan, Burak;Uysal, Cagri A;Ertas, Nilgun M
10.1007/s00266-020-01805-z
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Securing Posterior Auricular Incision with Button Headbands in Prominent Ear Patients Wearing Surgical Masks for Self-protection in the Pandemic. [Abstract]: In this letter, we describe an attachment on conventional headbands recommended for the postoperative period in prominent ear patients to confidently wea...
32,711,001
Diabetes Res Clin Pract
Characteristics of laboratory findings of COVID-19 patients with comorbid diabetes mellitus.
AIMS: Coronavirus disease (COVID-19), also referred to as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is instigated by a novel coronavirus. The disease was initially reported in Wuhan, China, in December 2019. Diabetes is a risk factor associated with adverse outcomes. Herein, our objective was to inv...
covid-19;laboratory findings;sars-cov-2;t2dm
Journal Article
Jing Liang, Jing;Liu, Jun;Chen, Yong;Ye, Bo;Li, Na;Wang, Xiao;Tang, Min;Shao, Jiaqing
10.1016/j.diabres.2020.108351
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Characteristics of laboratory findings of COVID-19 patients with comorbid diabetes mellitus. [Abstract]: AIMS: Coronavirus disease (COVID-19), also referred to as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is instigated by a novel coronavirus. The disease was initially reported in Wuhan, Chi...
32,979,456
J Dent
The perceived impact of Covid-19 on periodontal practice in the United Kingdom: A questionnaire study.
INTRODUCTION: COVID-19 has impacted dentistry in unprecedented ways. OBJECTIVE: The following research aimed to investigate the impact of the COVID-19 pandemic on periodontal practice in the United Kingdom using the COM-B (Capability Opportunity Motivation-Behaviour) model as the basis for a questionnaire. BASIC RESEAR...
com-b;covid-19;periodontics
Journal Article
Nibali, L;Ide, M;Ng, D;Buontempo, Z;Clayton, Y;Asimakopoulou, K
10.1016/j.jdent.2020.103481
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The perceived impact of Covid-19 on periodontal practice in the United Kingdom: A questionnaire study. [Abstract]: INTRODUCTION: COVID-19 has impacted dentistry in unprecedented ways. OBJECTIVE: The following research aimed to investigate the impact of the COVID-19 pandemic on periodontal practice in the Unite...
32,906,197
J Card Surg
COVID 19-The Spanish perspective.
BACKGROUND: COVID-19 hit hard worldwide. There has been an impact on global activity of cardiac surgery. Spain has been one of the hardest hit countries with one of the highest per population incidences and death. METHODS: The following is an overview of the epidemiology and impact on resources, the caseload and surgic...
covid-19;spain;cardiac surgery;pandemic;perspective
Journal Article;Review
Perez de la Sota, Enrique;Pinon, Miguel;Quintana, Eduard;Mestres, Carlos A
10.1111/jocs.14994
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID 19-The Spanish perspective. [Abstract]: BACKGROUND: COVID-19 hit hard worldwide. There has been an impact on global activity of cardiac surgery. Spain has been one of the hardest hit countries with one of the highest per population incidences and death. METHODS: The following is an overview of the epidem...
32,434,627
Ir J Psychol Med
Lockdown in a specialised rehabilitation unit: the best of times.
Specialised rehabilitation units offer inpatient multi-disciplinary rehabilitation for individuals with severe and enduring mental illness. A cornerstone of therapy is the work in the community through further education and community organisations. However, coronavirus restrictions have meant that such external support...
psychotherapy group;rehabilitation;schizophrenia;therapeutic community;trauma
Journal Article;Review
Glancy, D;Reilly, L;Cobbe, C;Glynn, M;Punchoo, S;Foy, K
10.1017/ipm.2020.50
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Lockdown in a specialised rehabilitation unit: the best of times. [Abstract]: Specialised rehabilitation units offer inpatient multi-disciplinary rehabilitation for individuals with severe and enduring mental illness. A cornerstone of therapy is the work in the community through further education and community...
32,425,648
Microbes Infect
A preliminary study on serological assay for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 238 admitted hospital patients.
In this study, we aimed to evaluate the diagnostic value of serological assay for SARS-CoV-2. A newly-developed ELISA assay for IgM and IgG antibodies against N protein of SARS-CoV-2 was used to screen the serums of 238 admitted hospital patients between February 6 and February 14, 2020 with confirmed or suspected SARS...
diagnosis;nucleic acid test;sars-cov-2;serological assay
Journal Article;Research Support, Non-U.S. Gov't
Liu, Lei;Liu, Wanbing;Zheng, Yaqiong;Jiang, Xiaojing;Kou, Guomei;Ding, Jinya;Wang, Qiongshu;Huang, Qianchuan;Ding, Yinjuan;Ni, Wenxu;Wu, Wanlei;Tang, Shi;Tan, Li;Hu, Zhenhong;Xu, Weitian;Zhang, Yong;Zhang, Bo;Tang, Zhongzhi;Zhang, Xinhua;Li, Honghua;Rao, Zhiguo;Jiang, Hui;Ren, Xingfeng;Wang, Shengdian;Zheng, Shangen
10.1016/j.micinf.2020.05.008
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: A preliminary study on serological assay for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 238 admitted hospital patients. [Abstract]: In this study, we aimed to evaluate the diagnostic value of serological assay for SARS-CoV-2. A newly-developed ELISA assay for IgM and IgG antibodies against...
32,425,200
Am J Obstet Gynecol
Prenatal care redesign: creating flexible maternity care models through virtual care.
Each year, nearly 4 million pregnant patients in the United States receive prenatal care-a crucial preventive service that improves pregnancy outcomes for mothers and their children. National guidelines currently recommend 12-14 in-person prenatal visits, a schedule that has remained unchanged since 1930. When scrutini...
covid-19;care delivery;gestational diabetes screening;patient-centered care;postpartum care;prenatal care;telemedicine;ultrasound;vaccination
Journal Article;Research Support, N.I.H., Extramural
Peahl, Alex F;Smith, Roger D;Moniz, Michelle H
10.1016/j.ajog.2020.05.029
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Prenatal care redesign: creating flexible maternity care models through virtual care. [Abstract]: Each year, nearly 4 million pregnant patients in the United States receive prenatal care-a crucial preventive service that improves pregnancy outcomes for mothers and their children. National guidelines currently ...
32,640,331
Food Chem Toxicol
Analysis of the intricate effects of polyunsaturated fatty acids and polyphenols on inflammatory pathways in health and disease.
Prevention and treatment of non-communicable diseases (NCDs), including cardiovascular disease, diabetes, obesity, cancer, Alzheimer's and Parkinson's disease, arthritis, non-alcoholic fatty liver disease and various infectious diseases; lately most notably COVID-19 have been in the front line of research worldwide. Al...
inflammation;nutraceuticals;polyphenols;polyunsaturated fatty acids
Journal Article;Review
Margina, Denisa;Ungurianu, Anca;Purdel, Carmen;Nitulescu, George Mihai;Tsoukalas, Dimitris;Sarandi, Evangelia;Thanasoula, Maria;Burykina, Tatyana I;Tekos, Fotis;Buha, Aleksandra;Nikitovic, Dragana;Kouretas, Demetrios;Tsatsakis, Aristidis Michael
10.1016/j.fct.2020.111558
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Analysis of the intricate effects of polyunsaturated fatty acids and polyphenols on inflammatory pathways in health and disease. [Abstract]: Prevention and treatment of non-communicable diseases (NCDs), including cardiovascular disease, diabetes, obesity, cancer, Alzheimer's and Parkinson's disease, arthritis,...
32,957,901
Curr Protein Pept Sci
Drug Repurposing Approaches: Existing Leads For Novel Threats And Drug Targets.
Drug Repurposing (DR) is an alternative to the traditional drug discovery process. It is cost and time effective, with high returns and low risk process that can tackle the increasing need for interventions for varied diseases and new outbreaks. Repurposing of old drugs for other diseases has gained a wider attention, ...
covid-19;cancer;computational approaches;drug repurposing;phenotypic screening and collaborative models
Journal Article
Usha, Talambedu;Middha, Sushil K;Kukanur, Anusha A;Shravani, Rachamadugu V;Anupama, Mahantesh N;Harshitha, Nagasamudram;Rahamath, Ameena;Kukanuri, Sumedha A;Goyal, Arvind K
10.2174/1389203721666200921152853
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Drug Repurposing Approaches: Existing Leads For Novel Threats And Drug Targets. [Abstract]: Drug Repurposing (DR) is an alternative to the traditional drug discovery process. It is cost and time effective, with high returns and low risk process that can tackle the increasing need for interventions for varied d...
33,029,657
Diabetologia
Antibody response to multiple antigens of SARS-CoV-2 in patients with diabetes: an observational cohort study.
AIMS/HYPOTHESIS: The aim of the study was to characterise the humoral response against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in patients with diabetes. Demonstrating the ability to mount an appropriate antibody response in the presence of hyperglycaemia is relevant for the comprehension of mechan...
antibodies;covid-19;diabetes;human;humoral response;receptor-binding domain;sars-cov-2;survival rate
Journal Article;Observational Study
Lampasona, Vito;Secchi, Massimiliano;Scavini, Marina;Bazzigaluppi, Elena;Brigatti, Cristina;Marzinotto, Ilaria;Davalli, Alberto;Caretto, Amelia;Laurenzi, Andrea;Martinenghi, Sabina;Molinari, Chiara;Vitali, Giordano;Di Filippo, Luigi;Mercalli, Alessia;Melzi, Raffaella;Tresoldi, Cristina;Rovere-Querini, Patrizia;Landoni,...
10.1007/s00125-020-05284-4
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Antibody response to multiple antigens of SARS-CoV-2 in patients with diabetes: an observational cohort study. [Abstract]: AIMS/HYPOTHESIS: The aim of the study was to characterise the humoral response against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in patients with diabetes. Demonstrating...
32,850,612
Front Public Health
A Predicting Nomogram for Mortality in Patients With COVID-19.
Background: The global COVID-19 epidemic remains severe, with the cumulative global death toll reaching more than 207,170 as of May 2, 2020 (1). Purpose: Our research objective is to establish a reliable nomogram to predict mortality in COVID-19 patients. The nomogram can help us distinguish between patients who are at...
covid-19;mortality;nomogram;patients;predict
Journal Article
Pan, Deng;Cheng, Dandan;Cao, Yiwei;Hu, Chuan;Zou, Fenglin;Yu, Wencheng;Xu, Tao
10.3389/fpubh.2020.00461
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: A Predicting Nomogram for Mortality in Patients With COVID-19. [Abstract]: Background: The global COVID-19 epidemic remains severe, with the cumulative global death toll reaching more than 207,170 as of May 2, 2020 (1). Purpose: Our research objective is to establish a reliable nomogram to predict mortality in...
32,450,197
Int J Antimicrob Agents
Extra-respiratory manifestations of COVID-19.
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global health threat. Although most patients with COVID-19 manifest fever and respiratory tract symptoms, SARS-CoV-2 infection may also involve other organs/systems and present with extra-respirator...
covid-19;epidemiology;extra-respiratory manifestations;sars-cov-2
Journal Article;Review
Lai, Chih-Cheng;Ko, Wen-Chien;Lee, Ping-Ing;Jean, Shio-Shin;Hsueh, Po-Ren
10.1016/j.ijantimicag.2020.106024
[ 1, 1, 1, 1, 0, 0, 0 ]
[Title]: Extra-respiratory manifestations of COVID-19. [Abstract]: Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global health threat. Although most patients with COVID-19 manifest fever and respiratory tract symptoms, SARS-CoV-2 infection may ...
32,884,878
Cureus
An Unusual Case of Moraxella osleonsis Bacteremia in an Immunocompetent Patient With SARS-CoV-2 Infection.
Moraxella osleonsis (M.osleonsis ) is an organism that rarely presents with bacteremia in immunocompetent patients. We report a case of an immunocompetent 59-year-old male with a recent SARS-CoV-2 infection that developed M. osleonsis bacteremia. We believe that SARS-CoV-2 infection may have played a role in developing...
bacteremia;cd-4;cd-8;coronavirus;covid-19;immunocompetent;immunocompromised;moraxella;regulatory t cells;t cells
Case Reports
Veerabathini, Bala C;Manthani, Kaushik;Gandhi, Sandeep
10.7759/cureus.10154
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: An Unusual Case of Moraxella osleonsis Bacteremia in an Immunocompetent Patient With SARS-CoV-2 Infection. [Abstract]: Moraxella osleonsis (M.osleonsis ) is an organism that rarely presents with bacteremia in immunocompetent patients. We report a case of an immunocompetent 59-year-old male with a recent SARS-C...
32,818,263
Eur J Public Health
The pandemic predominantly hits poor neighbourhoods? SARS-CoV-2 infections and COVID-19 fatalities in German districts.
BACKGROUND: Reports from the UK and the USA suggest that coronavirus disease 2019 (COVID-19) predominantly affects poorer neighbourhoods. This article paints a more complex picture by distinguishing between a first and second phase of the pandemic. The initial spread of infections and its correlation with socio-economi...
Journal Article
Plumper, Thomas;Neumayer, Eric
10.1093/eurpub/ckaa168
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The pandemic predominantly hits poor neighbourhoods? SARS-CoV-2 infections and COVID-19 fatalities in German districts. [Abstract]: BACKGROUND: Reports from the UK and the USA suggest that coronavirus disease 2019 (COVID-19) predominantly affects poorer neighbourhoods. This article paints a more complex pictur...
32,837,983
Genes Dis
Coronavirus disease 2019 (COVID-19): cytokine storms, hyper-inflammatory phenotypes, and acute respiratory distress syndrome.
Coronavirus Disease 2019 (COVID-19) was first identified in China at the end of 2019. Acute respiratory distress syndrome (ARDS) represents the most common and serious complication of COVID-19. Cytokine storms are a pathophysiological feature of COVID-19 and play an important role in distinguishing hyper-inflammatory s...
acute respiratory distress syndrome;covid-19;cytokine storm;hyper-inflammatory host response;sars-cov-2
Journal Article;Review
Lin, Shi-Hui;Zhao, Yi-Si;Zhou, Dai-Xing;Zhou, Fa-Chun;Xu, Fang
10.1016/j.gendis.2020.06.009
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: Coronavirus disease 2019 (COVID-19): cytokine storms, hyper-inflammatory phenotypes, and acute respiratory distress syndrome. [Abstract]: Coronavirus Disease 2019 (COVID-19) was first identified in China at the end of 2019. Acute respiratory distress syndrome (ARDS) represents the most common and serious compl...
33,072,850
Model Earth Syst Environ
Impact of population density on Covid-19 infected and mortality rate in India.
The Covid-19 is a highly contagious disease which becomes a serious global health concern. The residents living in areas with high population density, such as big or metropolitan cities, have a higher probability to come into close contact with others and consequently any contagious disease is expected to spread rapidl...
covid-19;india;infection and mortality rate;population density
Journal Article
Bhadra, Arunava;Mukherjee, Arindam;Sarkar, Kabita
10.1007/s40808-020-00984-7
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Impact of population density on Covid-19 infected and mortality rate in India. [Abstract]: The Covid-19 is a highly contagious disease which becomes a serious global health concern. The residents living in areas with high population density, such as big or metropolitan cities, have a higher probability to come...
32,729,248
Mol Syst Biol
In vitro and in vivo identification of clinically approved drugs that modify ACE2 expression.
The COVID-19 pandemic caused by SARS-CoV-2 has is a global health challenge. Angiotensin-converting enzyme 2 (ACE2) is the host receptor for SARS-CoV-2 entry. Recent studies have suggested that patients with hypertension and diabetes treated with ACE inhibitors (ACEIs) or angiotensin receptor blockers have a higher ris...
angiotensin i-converting enzyme 2;coronavirus disease 2019;dexamethasone;drug-modifying ace2 expression;severe acute respiratory syndrome coronavirus 2
Journal Article;Research Support, N.I.H., Extramural
Sinha, Sanju;Cheng, Kuoyuan;Schaffer, Alejandro A;Aldape, Kenneth;Schiff, Eyal;Ruppin, Eytan
10.15252/msb.20209628
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: In vitro and in vivo identification of clinically approved drugs that modify ACE2 expression. [Abstract]: The COVID-19 pandemic caused by SARS-CoV-2 has is a global health challenge. Angiotensin-converting enzyme 2 (ACE2) is the host receptor for SARS-CoV-2 entry. Recent studies have suggested that patients wi...
32,833,200
Methods Mol Biol
Coronaviruses: An Updated Overview of Their Replication and Pathogenesis.
Coronaviruses (CoVs), enveloped positive-sense RNA viruses, are characterized by club-like spikes that project from their surface, an unusually large RNA genome, and a unique replication strategy. CoVs cause a variety of diseases in mammals and birds ranging from enteritis in cows and pigs, and upper respiratory tract ...
coronavirus;mers-cov;nidovirales;positive-sense rna viruses;sars-cov
Journal Article;Review
Wang, Yuhang;Grunewald, Matthew;Perlman, Stanley
10.1007/978-1-0716-0900-2_1
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Coronaviruses: An Updated Overview of Their Replication and Pathogenesis. [Abstract]: Coronaviruses (CoVs), enveloped positive-sense RNA viruses, are characterized by club-like spikes that project from their surface, an unusually large RNA genome, and a unique replication strategy. CoVs cause a variety of dise...
32,834,401
Int Stat Rev
Statistical Implementations of Agent-Based Demographic Models.
A variety of demographic statistical models exist for studying population dynamics when individuals can be tracked over time. In cases where data are missing due to imperfect detection of individuals, the associated measurement error can be accommodated under certain study designs (e.g. those that involve multiple surv...
bayesian;mcmc;emulator;individual-based model;mechanistic model
Journal Article
Hooten, Mevin;Wikle, Christopher;Schwob, Michael
10.1111/insr.12399
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Statistical Implementations of Agent-Based Demographic Models. [Abstract]: A variety of demographic statistical models exist for studying population dynamics when individuals can be tracked over time. In cases where data are missing due to imperfect detection of individuals, the associated measurement error ca...
32,951,900
Otolaryngol Clin North Am
Pediatric Otolaryngology in the COVID-19 Era.
Although the majority of attention to the health care impact of COVID-19 has focused on adult first responders and critical care providers, the pandemic has had a profound effect on the entire health care industry, including the pediatric otolaryngology community. This article highlights the unique ramifications of COV...
covid-19;nose and throat;pediatric ear;pediatric otolaryngology
Journal Article;Review
Sobol, Steven E;Preciado, Diego;Rickert, Scott M
10.1016/j.otc.2020.08.005
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Pediatric Otolaryngology in the COVID-19 Era. [Abstract]: Although the majority of attention to the health care impact of COVID-19 has focused on adult first responders and critical care providers, the pandemic has had a profound effect on the entire health care industry, including the pediatric otolaryngology...
32,472,688
Clin Infect Dis
Low prevalence of SARS-CoV-2 among pregnant and postpartum patients with universal screening in Seattle, Washington.
We found a low prevalence of SARS-CoV-2 (2.7% [5/188]) among pregnant and postpartum patients after initiating universal testing. Prevalence among symptomatic patients (22.2% [4/18]) was similar to initial targeted screening approaches (19.1% [8/42]). Among 170 asymptomatic patients, two were positive or inconclusive, ...
covid-19;sars-cov-2;pregnancy;universal screening;viral shedding
Journal Article
LaCourse, Sylvia M;Kachikis, Alisa;Blain, Michela;Simmons, LaVone E;Mays, James A;Pattison, Amber D;Salerno, Carol C;McCartney, Stephen A;Kretzer, Nicole M;Resnick, Rebecca;Shay, Rosemary L;Savitsky, Leah M;Curtin, Anna C;Huebner, Emily M;Ma, Kimberly K;Delaney, Shani;Delgado, Carlos;Schippers, Adrienne;Munson, Jeff;Po...
10.1093/cid/ciaa675
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Low prevalence of SARS-CoV-2 among pregnant and postpartum patients with universal screening in Seattle, Washington. [Abstract]: We found a low prevalence of SARS-CoV-2 (2.7% [5/188]) among pregnant and postpartum patients after initiating universal testing. Prevalence among symptomatic patients (22.2% [4/18])...
32,978,971
Clin Exp Immunol
Innate immunity during SARS-CoV-2: evasion strategies and activation trigger hypoxia and vascular damage.
Innate immune sensing of viral molecular patterns is essential for development of antiviral responses. Like many viruses, SARS-CoV-2 has evolved strategies to circumvent innate immune detection, including low cytosine-phosphate-guanosine (CpG) levels in the genome, glycosylation to shield essential elements including t...
covid-19;sars-cov-2;endothelia;immunology;inflammation
Journal Article;Review
Amor, S;Fernandez Blanco, L;Baker, D
10.1111/cei.13523
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Innate immunity during SARS-CoV-2: evasion strategies and activation trigger hypoxia and vascular damage. [Abstract]: Innate immune sensing of viral molecular patterns is essential for development of antiviral responses. Like many viruses, SARS-CoV-2 has evolved strategies to circumvent innate immune detection...
32,584,897
PLoS One
Threat of COVID-19 and emotional state during quarantine: Positive and negative affect as mediators in a cross-sectional study of the Spanish population.
AIMS: The objective of this study was therefore to analyze the effect of exceptionally stressful situations, such as the current health risk, on the cognitive and emotive state of the individual, that is, perceived threat and emotional state on affect and mood. METHOD: This was a cross-sectional study with snowball sam...
Journal Article
Perez-Fuentes, Maria Del Carmen;Molero Jurado, Maria Del Mar;Martos Martinez, Africa;Gazquez Linares, Jose Jesus
10.1371/journal.pone.0235305
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Threat of COVID-19 and emotional state during quarantine: Positive and negative affect as mediators in a cross-sectional study of the Spanish population. [Abstract]: AIMS: The objective of this study was therefore to analyze the effect of exceptionally stressful situations, such as the current health risk, on ...
33,039,095
Pathology
Clinical evaluation of SARS-CoV-2 point-of-care antibody tests.
The aim of this study was to assess the analytic and clinical performance of four rapid lateral flow point-of-care tests (POCTs) for identifying SARS-CoV-2-specific antibodies. A retrospective study was conducted between 22 January and 30 March 2020 on 132 serum samples for SARS-CoV-2-specific antibody detection referr...
covid-19;sars-cov-2;point-of-care testing;serology
Journal Article
Robosa, Roselle S;Sandaradura, Indy;Dwyer, Dominic E;O'Sullivan, Matthew V N
10.1016/j.pathol.2020.09.002
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical evaluation of SARS-CoV-2 point-of-care antibody tests. [Abstract]: The aim of this study was to assess the analytic and clinical performance of four rapid lateral flow point-of-care tests (POCTs) for identifying SARS-CoV-2-specific antibodies. A retrospective study was conducted between 22 January and...
33,001,832
J Med Internet Res
Application of an Artificial Intelligence Trilogy to Accelerate Processing of Suspected Patients With SARS-CoV-2 at a Smart Quarantine Station: Observational Study.
BACKGROUND: As the COVID-19 epidemic increases in severity, the burden of quarantine stations outside emergency departments (EDs) at hospitals is increasing daily. To address the high screening workload at quarantine stations, all staff members with medical licenses are required to work shifts in these stations. Theref...
covid-19;sars-cov-2;artificial intelligence;quarantine station;smart device assisted decision making
Journal Article;Observational Study;Research Support, Non-U.S. Gov't
Liu, Ping-Yen;Tsai, Yi-Shan;Chen, Po-Lin;Tsai, Huey-Pin;Hsu, Ling-Wei;Wang, Chi-Shiang;Lee, Nan-Yao;Huang, Mu-Shiang;Wu, Yun-Chiao;Ko, Wen-Chien;Yang, Yi-Ching;Chiang, Jung-Hsien;Shen, Meng-Ru
10.2196/19878
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Application of an Artificial Intelligence Trilogy to Accelerate Processing of Suspected Patients With SARS-CoV-2 at a Smart Quarantine Station: Observational Study. [Abstract]: BACKGROUND: As the COVID-19 epidemic increases in severity, the burden of quarantine stations outside emergency departments (EDs) at h...
32,609,085
SICOT J
COVID-19. An update for orthopedic surgeons.
The COVID-19 pandemic has affected our world in a short period of time, and the orthopedic surgery practice was not an exclusion. Elective care was deferred in most health care facilities and emergency care was continued with strict precautions. With rapid progression of the pandemic, the response of the medical commun...
covid-19;orthopaedics
Journal Article
Abdelnasser, Mohammad Kamal;Morsy, Mohamed;Osman, Ahmed E;AbdelKawi, Ayman F;Ibrahim, Mahmoud Fouad;Eisa, Amr;Fadle, Amr A;Hatem, Amr;Anter Abdelhameed, Mohammed;Hassan, Ahmed Abdelazim A;Shawky Abdelgawaad, Ahmed
10.1051/sicotj/2020022
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19. An update for orthopedic surgeons. [Abstract]: The COVID-19 pandemic has affected our world in a short period of time, and the orthopedic surgery practice was not an exclusion. Elective care was deferred in most health care facilities and emergency care was continued with strict precautions. With rap...
32,742,475
J Cancer
Expression of the SAR2-Cov-2 receptor ACE2 reveals the susceptibility of COVID-19 in non-small cell lung cancer.
Recent studies have revealed that cancer patients had a higher risk of having coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), compared to patients without cancer. The expression of angiotensin-converting enzyme 2 (ACE2), the receptor of SARS-CoV-2, was aberra...
ace2;covid-19;sars-cov-2;expression;receptor;survival
Journal Article
Zhang, Hongming;Quek, Kelly;Chen, Runzhe;Chen, Jibei;Chen, Baoan
10.7150/jca.49462
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Expression of the SAR2-Cov-2 receptor ACE2 reveals the susceptibility of COVID-19 in non-small cell lung cancer. [Abstract]: Recent studies have revealed that cancer patients had a higher risk of having coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),...
32,550,701
Int Braz J Urol
Endourology and Benign Prostatic Hyperplasia in COVID-19 Pandemic.
The new disease COVID-19 pandemic has completely modified our lifestyle, changing our personal habits and daily activities and strongly our professional activity. Following World Health Organization (WHO) and health care authorities around the World recommendations, all elective surgeries from benign diagnose procedure...
covid-19 [supplementary concept];pandemics;prostatic hyperplasia
Journal Article;Review
Pinto, Alexis M Alva;Gonzalez, Mariano Sebastian
10.1590/S1677-5538.IBJU.2020.S104
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Endourology and Benign Prostatic Hyperplasia in COVID-19 Pandemic. [Abstract]: The new disease COVID-19 pandemic has completely modified our lifestyle, changing our personal habits and daily activities and strongly our professional activity. Following World Health Organization (WHO) and health care authorities...
32,799,883
J Transl Med
Cancer patients and coronavirus disease 2019: evidence in context.
In the rapidly evolving coronavirus disease 2019 (COVID-19) outbreak, inherent literature has been increasing at an impressive rate. Such a dynamic scenario imposes the necessity to define a new framework for cancer care. The first emerging evidence has transmitted contrasting messages with regards to cancer care manag...
covid-19 pandemic;cancer care;cancer patients;health care reorganization
Letter;Comment
Barba, Maddalena;Krasniqi, Eriseld;Ciliberto, Gennaro;Vici, Patrizia
10.1186/s12967-020-02483-w
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Cancer patients and coronavirus disease 2019: evidence in context. [Abstract]: In the rapidly evolving coronavirus disease 2019 (COVID-19) outbreak, inherent literature has been increasing at an impressive rate. Such a dynamic scenario imposes the necessity to define a new framework for cancer care. The first ...
32,614,776
J Med Internet Res
Unmuting Medical Students' Education: Utilizing Telemedicine During the COVID-19 Pandemic and Beyond.
Due to the coronavirus disease (COVID-19) pandemic, medical schools have paused traditional clerkships, eliminating direct patient encounters from medical students' education for the immediate future. Telemedicine offers opportunities in a variety of specialties that can augment student education during this time. The ...
covid-19;curriculum;education, medical, undergraduate;medical education;medical school;telemedicine
Journal Article
Iancu, Ariella Magen;Kemp, Michael Thomas;Alam, Hasan Badre
10.2196/19667
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Unmuting Medical Students' Education: Utilizing Telemedicine During the COVID-19 Pandemic and Beyond. [Abstract]: Due to the coronavirus disease (COVID-19) pandemic, medical schools have paused traditional clerkships, eliminating direct patient encounters from medical students' education for the immediate futu...
32,317,180
Eur Urol
Coronavirus Disease 2019 Pneumonia in Immunosuppressed Renal Transplant Recipients: A Summary of 10 Confirmed Cases in Wuhan, China.
BACKGROUND: Previous studies on coronavirus disease 2019 (COVID-19) have focused on populations with normal immunity, but lack data on immunocompromised populations. OBJECTIVE: To evaluate the clinical features and outcomes of COVID-19 pneumonia in kidney transplant recipients. DESIGN, SETTING, AND PARTICIPANTS: A tota...
coronavirus disease 2019;immunosuppression;kidney transplantation;outcome;pneumonia
Journal Article
Zhu, Lan;Gong, Nianqiao;Liu, Bin;Lu, Xia;Chen, Dong;Chen, Song;Shu, Hongge;Ma, Ke;Xu, Xizhen;Guo, Zhiliang;Lu, Enfeng;Chen, Dongrui;Ge, Qinggang;Cai, Junchao;Jiang, Jipin;Wei, Lai;Zhang, Weijie;Chen, Gang;Chen, Zhishui
10.1016/j.eururo.2020.03.039
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Coronavirus Disease 2019 Pneumonia in Immunosuppressed Renal Transplant Recipients: A Summary of 10 Confirmed Cases in Wuhan, China. [Abstract]: BACKGROUND: Previous studies on coronavirus disease 2019 (COVID-19) have focused on populations with normal immunity, but lack data on immunocompromised populations. ...
33,047,480
ANZ J Surg
Impact of COVID-19-related social restrictions on orthopaedic trauma in a level 1 trauma centre in Sydney: the first wave.
BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic has affected communities worldwide. This study examines the impact that public health measures to control viral spread have had on orthopaedic trauma presenting to an Australian level 1 trauma centre. We hypothesized that the volume of orthopaedic trauma in t...
covid-19;hospital presentations;orthopaedic surgery;social distancing;trauma
Journal Article
Probert, Annabel C;Sivakumar, Brahman S;An, Vincent;Nicholls, Sarah L;Shatrov, Jobe G;Symes, Michael J;Ellis, Andrew M
10.1111/ans.16375
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Impact of COVID-19-related social restrictions on orthopaedic trauma in a level 1 trauma centre in Sydney: the first wave. [Abstract]: BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic has affected communities worldwide. This study examines the impact that public health measures to control viral spr...
32,756,383
J Clin Med
Venous Thromboembolism among Hospitalized Patients with COVID-19 Undergoing Thromboprophylaxis: A Systematic Review and Meta-Analysis.
BACKGROUND: Preliminary evidence indicates that prophylactic-dose thromboprophylaxis may be inadequate to control the increased risk of venous thromboembolism (VTE) in patients hospitalized for coronavirus disease 2019 (COVID-19) infection. Additionally, it remains unclear whether the D-dimer measurement is useful for ...
covid-19;deep vein thrombosis;pulmonary embolism;thromboprophylaxis;venous thromboembolism
Journal Article
Chi, Gerald;Lee, Jane J;Jamil, Adeel;Gunnam, Vamsikrishna;Najafi, Homa;Memar Montazerin, Sahar;Shojaei, Fahimehalsadat;Marszalek, Jolanta
10.3390/jcm9082489
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Venous Thromboembolism among Hospitalized Patients with COVID-19 Undergoing Thromboprophylaxis: A Systematic Review and Meta-Analysis. [Abstract]: BACKGROUND: Preliminary evidence indicates that prophylactic-dose thromboprophylaxis may be inadequate to control the increased risk of venous thromboembolism (VTE)...
32,299,750
Can J Cardiol
Post-Discharge Cardiac Care in the Era of Coronavirus 2019: How Should We Prepare?
The novel coronavirus 2019 disease (COVID-19) pandemic has placed intense pressure on health care organizations around the world. Among other concerns, there has been an increasing recognition of common and deleterious cardiovascular effects of COVID-19 based on preliminary studies. Furthermore, patients with preexisti...
Journal Article
Percy, Edward;Luc, Jessica G Y;Vervoort, Dominique;Hirji, Sameer;Ruel, Marc;Coutinho, Thais
10.1016/j.cjca.2020.04.006
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Post-Discharge Cardiac Care in the Era of Coronavirus 2019: How Should We Prepare? [Abstract]: The novel coronavirus 2019 disease (COVID-19) pandemic has placed intense pressure on health care organizations around the world. Among other concerns, there has been an increasing recognition of common and deleterio...
32,706,210
Rev Cardiovasc Med
Safe performance of echocardiography during the COVID-19 pandemic: a practical guide.
Coronavirus disease-2019 (COVID-19) outbreak has become a worldwide healthcare emergency, with continuously growing number of infected subjects. Considering the easy virus spread through respiratory droplets produced with cough, sneezes or spit or through close contact with infected people or surfaces, healthcare worke...
covid-19;sars-cov2;coronavirus;echocardiography;pandemic;personal protective equipment
Journal Article
Cameli, Matteo;Pastore, Maria Concetta;Henein, Michael;Aboumarie, Hatem Soliman;Mandoli, Giulia Elena;D'Ascenzi, Flavio;Cameli, Paolo;Franchi, Federico;Mondillo, Sergio;Valente, Serafina
10.31083/j.rcm.2020.02.90
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Safe performance of echocardiography during the COVID-19 pandemic: a practical guide. [Abstract]: Coronavirus disease-2019 (COVID-19) outbreak has become a worldwide healthcare emergency, with continuously growing number of infected subjects. Considering the easy virus spread through respiratory droplets produ...
32,902,818
Geroscience
A geroscience perspective on immune resilience and infectious diseases: a potential case for metformin.
We are in the midst of the global pandemic. Though acute respiratory coronavirus (SARS-COV2) that leads to COVID-19 infects people of all ages, severe symptoms and mortality occur disproportionately in older adults. Geroscience interventions that target biological aging could decrease risk across multiple age-related d...
aging;covid-19;geroscience;immunity;metformin
Journal Article
Justice, Jamie N;Gubbi, Sriram;Kulkarni, Ameya S;Bartley, Jenna M;Kuchel, George A;Barzilai, Nir
10.1007/s11357-020-00261-6
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: A geroscience perspective on immune resilience and infectious diseases: a potential case for metformin. [Abstract]: We are in the midst of the global pandemic. Though acute respiratory coronavirus (SARS-COV2) that leads to COVID-19 infects people of all ages, severe symptoms and mortality occur disproportionat...
32,870,435
Plant Foods Hum Nutr
Potential of Plant Proteins Digested In Silico by Gastrointestinal Enzymes as Nutritional Supplement for COVID-19 Patients.
Currently, no specific drug and vaccine are available for the new coronavirus SARS-CoV-2, and nutritional supplementation should be helpful. This study tried to provide reference for protein supplementation. Specifically, in silico method was employed to simulate protein degradation by gastrointestinal enzymes and to p...
covid-19;in silico evaluation;oligopeptides;protein supplementation;spike
Journal Article
Luo, Zhen;Su, Keying;Zhang, Xuewu
10.1007/s11130-020-00850-y
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Potential of Plant Proteins Digested In Silico by Gastrointestinal Enzymes as Nutritional Supplement for COVID-19 Patients. [Abstract]: Currently, no specific drug and vaccine are available for the new coronavirus SARS-CoV-2, and nutritional supplementation should be helpful. This study tried to provide refere...
32,973,879
Front Genet
Single Cell RNA-seq Data Analysis Reveals the Potential Risk of SARS-CoV-2 Infection Among Different Respiratory System Conditions.
COVID-19 (Coronavirus Disease 2019) has been an ongoing pandemic, resulting in an increase in people being infected globally. Understanding the potential risk of infection for people under different respiratory system conditions is important and will help prevent disease spreading. We explored and collected five publis...
ace2;covid-19;tmprss2;respiratory system;single cell transcriptome
Journal Article
Zhang, Qiang;Yue, Yuanyi;Tan, Huiwen;Liu, Yishu;Zeng, Yin;Xiao, Li
10.3389/fgene.2020.00942
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Single Cell RNA-seq Data Analysis Reveals the Potential Risk of SARS-CoV-2 Infection Among Different Respiratory System Conditions. [Abstract]: COVID-19 (Coronavirus Disease 2019) has been an ongoing pandemic, resulting in an increase in people being infected globally. Understanding the potential risk of infec...
33,038,909
Curr Pharm Biotechnol
Targeted delivery of CRISPR/Cas13 as a promising therapeutic approach to treat SARS-CoV-2.
In the worldwide scale, the outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to extensive damage to the health system as well as the global economy. Hitherto, there has been no approved drug or vaccine for this disease. Therefore, the use of general antiviral drugs is at the first li...
covid-19;crispr/cas13;sars-cov-2;antiviral.;genome;infection;virosome
Journal Article
Goudarzi, Kazem Abaszadeh;Nematollahi, Mohammad Hadi;Khanbabaei, Hashem;Nave, Hossein Hosseini;Mirzaei, Hamid Reza;Pourghadamyari, Hossein;Sahebkar, Amirhossein
10.2174/1389201021666201009154517
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Targeted delivery of CRISPR/Cas13 as a promising therapeutic approach to treat SARS-CoV-2. [Abstract]: In the worldwide scale, the outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to extensive damage to the health system as well as the global economy. Hitherto, there has bee...
32,315,948
Diabetes Metab Syndr
Case report of chloroquine therapy and hypoglycaemia in type 1 diabetes: What should we have in mind during the COVID-19 pandemic?
A type 1 diabetes patient experienced remission associated with chloroquine therapy while travelling to a malaria-endemic area. Chloroquine has immunomodulatory and hypoglycaemic effects and may become more frequently used due to the COVID-19 pandemic. Patients with type 1 diabetes treated with chloroquine should be mo...
chloroquine;hypoglycaemia;remission;type 1 diabetes
Case Reports;Letter
Baretic, Maja
10.1016/j.dsx.2020.04.014
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Case report of chloroquine therapy and hypoglycaemia in type 1 diabetes: What should we have in mind during the COVID-19 pandemic? [Abstract]: A type 1 diabetes patient experienced remission associated with chloroquine therapy while travelling to a malaria-endemic area. Chloroquine has immunomodulatory and hyp...
32,764,381
Int J Environ Res Public Health
Excess Deaths and Hospital Admissions for COVID-19 Due to a Late Implementation of the Lockdown in Italy.
In Italy, the COVID-19 epidemic curve started to flatten when the health system had already exceeded its capacity, raising concerns that the lockdown was indeed delayed. The aim of this study was to evaluate the health effects of late implementation of the lockdown in Italy. Using national data on the daily number of C...
covid-19;evaluation;health;healthcare;late implementation;lockdown
Journal Article
Palladino, Raffaele;Bollon, Jordy;Ragazzoni, Luca;Barone-Adesi, Francesco
10.3390/ijerph17165644
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Excess Deaths and Hospital Admissions for COVID-19 Due to a Late Implementation of the Lockdown in Italy. [Abstract]: In Italy, the COVID-19 epidemic curve started to flatten when the health system had already exceeded its capacity, raising concerns that the lockdown was indeed delayed. The aim of this study w...
32,790,639
J Med Internet Res
Willingness to Use Home Collection Methods to Provide Specimens for SARS-CoV-2/COVID-19 Research: Survey Study.
BACKGROUND: Innovative laboratory testing approaches for SARS-CoV-2 infection and immune response are needed to conduct research to establish estimates of prevalence and incidence. Self-specimen collection methods have been successfully used in HIV and sexually transmitted infection research and can provide a feasible ...
covid-19;sars-cov-2;infectious disease;public health;research;specimen collection;survey;test;virus
Journal Article;Research Support, N.I.H., Extramural
Hall, Eric William;Luisi, Nicole;Zlotorzynska, Maria;Wilde, Gretchen;Sullivan, Patrick;Sanchez, Travis;Bradley, Heather;Siegler, Aaron J
10.2196/19471
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Willingness to Use Home Collection Methods to Provide Specimens for SARS-CoV-2/COVID-19 Research: Survey Study. [Abstract]: BACKGROUND: Innovative laboratory testing approaches for SARS-CoV-2 infection and immune response are needed to conduct research to establish estimates of prevalence and incidence. Self-s...
32,502,664
Int J Infect Dis
Air pollution and temperature are associated with increased COVID-19 incidence: A time series study.
OBJECTIVES: Although COVID-19 is known to be caused by human-to-human transmission, it remains largely unclear whether ambient air pollutants and meteorological parameters could promote its transmission. METHODS: A retrospective study was conducted to study whether air quality index (AQI), four ambient air pollutants (...
aqi;ambient air pollutant;covid-19;sars-cov-2;temperature
Journal Article
Li, He;Xu, Xiao-Long;Dai, Da-Wei;Huang, Zhen-Yu;Ma, Zhuang;Guan, Yan-Jun
10.1016/j.ijid.2020.05.076
[ 0, 0, 1, 0, 1, 0, 0 ]
[Title]: Air pollution and temperature are associated with increased COVID-19 incidence: A time series study. [Abstract]: OBJECTIVES: Although COVID-19 is known to be caused by human-to-human transmission, it remains largely unclear whether ambient air pollutants and meteorological parameters could promote its transmis...
32,817,223
J Virol
Cryo-electron Microscopy Structure of the Swine Acute Diarrhea Syndrome Coronavirus Spike Glycoprotein Provides Insights into Evolution of Unique Coronavirus Spike Proteins.
Coronaviruses (CoV) have caused a number of major epidemics in humans and animals, including the current pandemic of coronavirus disease 2019 (COVID-19), which has brought a renewed focus on the evolution and interspecies transmission of coronaviruses. Swine acute diarrhea syndrome coronavirus (SADS-CoV), which was rec...
coronavirus;cryo-em;protein structure-function;spike protein;virus entry
Journal Article;Research Support, Non-U.S. Gov't
Guan, Hongxin;Wang, Youwang;Perculija, Vanja;Saeed, Abdullah F U H;Liu, Yichang;Li, Jinyu;Jan, Syed Sajid;Li, Yu;Zhu, Ping;Ouyang, Songying
10.1128/JVI.01301-20
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Cryo-electron Microscopy Structure of the Swine Acute Diarrhea Syndrome Coronavirus Spike Glycoprotein Provides Insights into Evolution of Unique Coronavirus Spike Proteins. [Abstract]: Coronaviruses (CoV) have caused a number of major epidemics in humans and animals, including the current pandemic of coronavi...
32,836,897
Rechtsmedizin (Berl)
Evidence for systematic autopsies in COVID-19 positive deceased: Case report of the first German investigated COVID-19 death.
Forensic medicine and pathology involve specific health risks, whereby health workers are dealing with microorganisms, cells or parasites, which are referred to as biological agents. Biological agents are divided into four categories according to section sign 3 of the Biological Agents Ordinance. The newly identified c...
biological agents ordinance;covid-19;deceased;high risk autopsy;sars-cov2
Journal Article
Fitzek, A;Sperhake, J;Edler, C;Schroder, A S;Heinemann, A;Heinrich, F;Ron, A;Mushumba, H;Lutgehetmann, M;Puschel, K
10.1007/s00194-020-00401-4
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Evidence for systematic autopsies in COVID-19 positive deceased: Case report of the first German investigated COVID-19 death. [Abstract]: Forensic medicine and pathology involve specific health risks, whereby health workers are dealing with microorganisms, cells or parasites, which are referred to as biologica...
32,904,503
Int J Hosp Manag
Creating a safe haven during the crisis: How organizations can achieve deep compliance with COVID-19 safety measures in the hospitality industry.
The COVID-19 health crisis has engendered a set of additional health and safety regulations and procedures (e.g. social distancing) to the hospitality industry. The purpose of this paper is to explore in-depth how organizations can facilitate employees' deep compliance with these procedures. Employing an instrumental c...
covid-19;crisis strategy;deep compliance;management commitment to safety
Journal Article
Hu, Xiaowen;Yan, Hongmin;Casey, Tristan;Wu, Chia-Huei
10.1016/j.ijhm.2020.102662
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Creating a safe haven during the crisis: How organizations can achieve deep compliance with COVID-19 safety measures in the hospitality industry. [Abstract]: The COVID-19 health crisis has engendered a set of additional health and safety regulations and procedures (e.g. social distancing) to the hospitality in...
32,984,870
Clin Infect Dis
Predicted Impact of COVID-19 on Neglected Tropical Disease Programs and the Opportunity for Innovation.
Due to the COVID-19 pandemic, many key neglected tropical disease (NTD) activities have been postponed. This hindrance comes at a time when the NTDs are progressing towards their ambitious goals for 2030. Mathematical modelling on several NTDs, namely gambiense sleeping sickness, lymphatic filariasis, onchocerciasis, s...
neglected tropical diseases;coronavirus;modeling
Journal Article
Toor, Jaspreet;Adams, Emily R;Aliee, Maryam;Amoah, Benjamin;Anderson, Roy M;Ayabina, Diepreye;Bailey, Robin;Basanez, Maria-Gloria;Blok, David J;Blumberg, Seth;Borlase, Anna;Rivera, Rocio Caja;Castano, Maria Soledad;Chitnis, Nakul;Coffeng, Luc E;Crump, Ronald E;Das, Aatreyee;Davis, Christopher N;Davis, Emma L;Deiner, Mi...
10.1093/cid/ciaa933
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Predicted Impact of COVID-19 on Neglected Tropical Disease Programs and the Opportunity for Innovation. [Abstract]: Due to the COVID-19 pandemic, many key neglected tropical disease (NTD) activities have been postponed. This hindrance comes at a time when the NTDs are progressing towards their ambitious goals ...
32,754,608
Front Med (Lausanne)
How Patients With Chronic Liver Diseases Succeed to Deal With COVID-19?
The human pathogenic coronaviruses cause infections of the respiratory tract from mild to severe ranges. Mild cases may look like the common cold, while cases with severe disease may represent severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS) and coronavirus disease 2019 (COVID-19). Curr...
covid-19;chronic liver diseases;coronaviruses;infectious disease;liver injuries;medical therapy
Journal Article;Review
Rezasoltani, Sama;Hatami, Behzad;Yadegar, Abbas;Asadzadeh Aghdaei, Hamid;Zali, Mohammad Reza
10.3389/fmed.2020.00398
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: How Patients With Chronic Liver Diseases Succeed to Deal With COVID-19? [Abstract]: The human pathogenic coronaviruses cause infections of the respiratory tract from mild to severe ranges. Mild cases may look like the common cold, while cases with severe disease may represent severe acute respiratory syndrome ...
32,674,824
J Am Med Dir Assoc
A Structured Tool for Communication and Care Planning in the Era of the COVID-19 Pandemic.
Residents in long-term care settings are particularly vulnerable to COVID-19 infections and, compared to younger adults, are at higher risk of poor outcomes and death. Given the poor prognosis of resuscitation outcomes for COVID-19 in general, the specter of COVID-19 in long-term care residents should prompt revisiting...
advance care planning;covid-19;long-term care;skilled nursing facility
Journal Article;Research Support, Non-U.S. Gov't
Gaur, Swati;Pandya, Naushira;Dumyati, Ghinwa;Nace, David A;Pandya, Kaylesh;Jump, Robin L P
10.1016/j.jamda.2020.05.062
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: A Structured Tool for Communication and Care Planning in the Era of the COVID-19 Pandemic. [Abstract]: Residents in long-term care settings are particularly vulnerable to COVID-19 infections and, compared to younger adults, are at higher risk of poor outcomes and death. Given the poor prognosis of resuscitatio...
32,492,874
J Clin Med
Using Machine Learning to Predict ICU Transfer in Hospitalized COVID-19 Patients.
OBJECTIVES: Approximately 20-30% of patients with COVID-19 require hospitalization, and 5-12% may require critical care in an intensive care unit (ICU). A rapid surge in cases of severe COVID-19 will lead to a corresponding surge in demand for ICU care. Because of constraints on resources, frontline healthcare workers ...
covid-19;critical care;intensive care units;random forest;supervised machine learning
Journal Article
Cheng, Fu-Yuan;Joshi, Himanshu;Tandon, Pranai;Freeman, Robert;Reich, David L;Mazumdar, Madhu;Kohli-Seth, Roopa;Levin, Matthew;Timsina, Prem;Kia, Arash
10.3390/jcm9061668
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Using Machine Learning to Predict ICU Transfer in Hospitalized COVID-19 Patients. [Abstract]: OBJECTIVES: Approximately 20-30% of patients with COVID-19 require hospitalization, and 5-12% may require critical care in an intensive care unit (ICU). A rapid surge in cases of severe COVID-19 will lead to a corresp...
32,408,699
Int J Mol Sci
Essential Oils as Antiviral Agents. Potential of Essential Oils to Treat SARS-CoV-2 Infection: An In-Silico Investigation.
Essential oils have shown promise as antiviral agents against several pathogenic viruses. In this work we hypothesized that essential oil components may interact with key protein targets of the 2019 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A molecular docking analysis was carried out using 171 esse...
covid-19;antiviral;corona virus;essential oils;molecular docking
Journal Article
Silva, Joyce Kelly R da;Figueiredo, Pablo Luis Baia;Byler, Kendall G;Setzer, William N
10.3390/ijms21103426
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Essential Oils as Antiviral Agents. Potential of Essential Oils to Treat SARS-CoV-2 Infection: An In-Silico Investigation. [Abstract]: Essential oils have shown promise as antiviral agents against several pathogenic viruses. In this work we hypothesized that essential oil components may interact with key prote...
32,675,661
J Bone Joint Surg Am
Musculoskeletal Consequences of COVID-19.
Coronavirus disease 2019 (COVID-19) is an emerging pandemic disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although the majority of patients who become infected with SARS-CoV-2 are asymptomatic or have mild symptoms, some patients develop severe symptoms that can permanently detract...
Journal Article
Disser, Nathaniel P;De Micheli, Andrea J;Schonk, Martin M;Konnaris, Maxwell A;Piacentini, Alexander N;Edon, Daniel L;Toresdahl, Brett G;Rodeo, Scott A;Casey, Ellen K;Mendias, Christopher L
10.2106/JBJS.20.00847
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Musculoskeletal Consequences of COVID-19. [Abstract]: Coronavirus disease 2019 (COVID-19) is an emerging pandemic disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although the majority of patients who become infected with SARS-CoV-2 are asymptomatic or have mild symptoms, som...
32,751,669
Int J Environ Res Public Health
Modelling the Effectiveness of Epidemic Control Measures in Preventing the Transmission of COVID-19 in Malaysia.
Malaysia is currently facing an outbreak of COVID-19. We aim to present the first study in Malaysia to report the reproduction numbers and develop a mathematical model forecasting COVID-19 transmission by including isolation, quarantine, and movement control measures. We utilized a susceptible, exposed, infectious, and...
covid-19;and recovered (seir);exposed;infectious;isolation;mathematical modeling;movement;susceptible
Journal Article
Gill, Balvinder Singh;Jayaraj, Vivek Jason;Singh, Sarbhan;Mohd Ghazali, Sumarni;Cheong, Yoon Ling;Md Iderus, Nuur Hafizah;Sundram, Bala Murali;Aris, Tahir Bin;Mohd Ibrahim, Hishamshah;Hong, Boon Hao;Labadin, Jane
10.3390/ijerph17155509
[ 0, 0, 1, 0, 1, 0, 0 ]
[Title]: Modelling the Effectiveness of Epidemic Control Measures in Preventing the Transmission of COVID-19 in Malaysia. [Abstract]: Malaysia is currently facing an outbreak of COVID-19. We aim to present the first study in Malaysia to report the reproduction numbers and develop a mathematical model forecasting COVID-...
32,709,566
J Surg Educ
Building Rapport and Earning the Surgical Patient's Trust in the Era of Social Distancing: Teaching Patient-Centered Communication During Video Conference Encounters to Medical Students.
BACKGROUND: Effective physician communication improves care, and many medical schools and residency programs have adopted communication focused curricula. The COVID-19 pandemic has shifted the doctor-patient communication paradigm with the rapid adoption of video-based medical appointments by the majority of the medica...
communication education;medical education;patient-centered communication;video conference encounters;virtual education
Journal Article
Newcomb, Anna B;Duval, Margaret;Bachman, Sharon L;Mohess, Denise;Dort, Jonathan;Kapadia, Muneera R
10.1016/j.jsurg.2020.06.018
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Building Rapport and Earning the Surgical Patient's Trust in the Era of Social Distancing: Teaching Patient-Centered Communication During Video Conference Encounters to Medical Students. [Abstract]: BACKGROUND: Effective physician communication improves care, and many medical schools and residency programs hav...
33,039,512
Am J Infect Control
Operating room air delivery design to protect patient and surgical site results in particles released at surgical table having greater concentration along walls of the room than at the instrument tray.
BACKGROUND: During the coronavirus disease 2019 (COVID-19) pandemic, recommendations have included that personnel not involved in procedures releasing airborne contaminants reduce their exposure by moving >2 m away. We tested whether air particle concentrations in operating rooms (ORs) are greater in the periphery, dow...
airborne contaminants;coronavirus disease 2019 (covid-19);operating room airflow;operating room management
Journal Article
Wagner, Jennifer A;Dexter, Franklin;Greeley, Damon G;Schreiber, Kevin
10.1016/j.ajic.2020.10.003
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Operating room air delivery design to protect patient and surgical site results in particles released at surgical table having greater concentration along walls of the room than at the instrument tray. [Abstract]: BACKGROUND: During the coronavirus disease 2019 (COVID-19) pandemic, recommendations have include...
32,420,674
Rev Med Virol
Three months of COVID-19: A systematic review and meta-analysis.
The pandemic of 2019 novel coronavirus (SARS-CoV-2019), reminiscent of the 2002-SARS-CoV outbreak, has completely isolated countries, disrupted health systems and partially paralyzed international trade and travel. In order to be better equipped to anticipate transmission of this virus to new regions, it is imperative ...
ace-2;covid-19;sars-cov;mathematical modeling;pandemic
Journal Article;Meta-Analysis;Research Support, Non-U.S. Gov't;Systematic Review
Rafiq, Danish;Batool, Asiya;Bazaz, M A
10.1002/rmv.2113
[ 0, 1, 1, 1, 0, 1, 0 ]
[Title]: Three months of COVID-19: A systematic review and meta-analysis. [Abstract]: The pandemic of 2019 novel coronavirus (SARS-CoV-2019), reminiscent of the 2002-SARS-CoV outbreak, has completely isolated countries, disrupted health systems and partially paralyzed international trade and travel. In order to be bett...
32,761,294
AAPS PharmSciTech
The COVID-19 Vaccine Race: Challenges and Opportunities in Vaccine Formulation.
In the race for a safe and effective vaccine against coronavirus disease (COVID)-19, pharmaceutical formulation science plays a critical role throughout the development, manufacturing, distribution, and vaccination phases. The proper choice of the type of vaccine, carrier or vector, adjuvant, excipients, dosage form, a...
adjuvant;coronavirus;mucosal vaccination;route of administration;vaccine
Journal Article;Review
Wang, Jieliang;Peng, Ying;Xu, Haiyue;Cui, Zhengrong;Williams, Robert O 3rd
10.1208/s12249-020-01744-7
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: The COVID-19 Vaccine Race: Challenges and Opportunities in Vaccine Formulation. [Abstract]: In the race for a safe and effective vaccine against coronavirus disease (COVID)-19, pharmaceutical formulation science plays a critical role throughout the development, manufacturing, distribution, and vaccination phas...
32,683,221
Med Hypotheses
Immuno-pathogenesis of nCOVID-19 and a possible host-directed therapy including anti-inflammatory and anti-viral prostaglandin (PG J2) for effective treatment and reduction in the death toll.
Coronaviruses including severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2, also known as 2019-nCoV especially in China) replicate and divide in host cells. During this they are partly hidden from the innate immune responses although inflammatory consequences of viral replication still occur. We propose that a...
anti-inflammatory and anti-viral prostaglandin;immuno-pathology;sars-cov-2
Journal Article;Review
Shahzad, Shakeel;Willcox, Mark
10.1016/j.mehy.2020.110080
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Immuno-pathogenesis of nCOVID-19 and a possible host-directed therapy including anti-inflammatory and anti-viral prostaglandin (PG J2) for effective treatment and reduction in the death toll. [Abstract]: Coronaviruses including severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2, also known as 2019-nCo...
32,691,015
Infect Dis Model
Using statistics and mathematical modelling to understand infectious disease outbreaks: COVID-19 as an example.
During an infectious disease outbreak, biases in the data and complexities of the underlying dynamics pose significant challenges in mathematically modelling the outbreak and designing policy. Motivated by the ongoing response to COVID-19, we provide a toolkit of statistical and mathematical models beyond the simple SI...
bias;covid-19;epidemic modelling;intervention;outbreak;parameter estimation
Journal Article
Overton, Christopher E;Stage, Helena B;Ahmad, Shazaad;Curran-Sebastian, Jacob;Dark, Paul;Das, Rajenki;Fearon, Elizabeth;Felton, Timothy;Fyles, Martyn;Gent, Nick;Hall, Ian;House, Thomas;Lewkowicz, Hugo;Pang, Xiaoxi;Pellis, Lorenzo;Sawko, Robert;Ustianowski, Andrew;Vekaria, Bindu;Webb, Luke
10.1016/j.idm.2020.06.008
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: Using statistics and mathematical modelling to understand infectious disease outbreaks: COVID-19 as an example. [Abstract]: During an infectious disease outbreak, biases in the data and complexities of the underlying dynamics pose significant challenges in mathematically modelling the outbreak and designing po...
32,944,840
Infection
Detection of SARS-CoV-2 in conjunctival secretions from patients without ocular symptoms.
PURPOSE: To evaluate the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in conjunctival secretions from patients without ocular symptoms. METHODS: Conjunctival swabs were prospectively collected from laboratory-confirmed Coronavirus disease 2019 (COVID-19) patients without ocular symptoms for ...
asymptomatic;conjunctiva;rt-pcr;sars-cov-2;shedding
Journal Article
Li, Xin;Chan, Jasper Fuk-Woo;Li, Kenneth Kai-Wang;Tso, Eugene Yuk-Keung;Yip, Cyril Chik-Yan;Sridhar, Siddharth;Chung, Tom Wai-Hin;Chiu, Kelvin Hei-Yeung;Hung, Derek Ling-Lung;Wu, Alan Ka-Lun;Chau, Sandy Ka-Yee;Liu, Raymond;Lung, Kwok-Cheung;Tam, Anthony Raymond;Cheng, Vincent Chi-Chung;To, Kelvin Kai-Wang;Chan, Kwok-Hu...
10.1007/s15010-020-01524-2
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Detection of SARS-CoV-2 in conjunctival secretions from patients without ocular symptoms. [Abstract]: PURPOSE: To evaluate the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in conjunctival secretions from patients without ocular symptoms. METHODS: Conjunctival swabs were prospectivel...
32,863,615
Chaos Solitons Fractals
Logistic equation and COVID-19.
The generalized logistic equation is used to interpret the COVID-19 epidemic data in several countries: Austria, Switzerland, the Netherlands, Italy, Turkey and South Korea. The model coefficients are calculated: the growth rate and the expected number of infected people, as well as the exponent indexes in the generali...
covid-19;generalized logistic model;logistic equation;mathematical modeling
Journal Article
Pelinovsky, Efim;Kurkin, Andrey;Kurkina, Oxana;Kokoulina, Maria;Epifanova, Anastasia
10.1016/j.chaos.2020.110241
[ 0, 0, 0, 0, 0, 1, 0 ]
[Title]: Logistic equation and COVID-19. [Abstract]: The generalized logistic equation is used to interpret the COVID-19 epidemic data in several countries: Austria, Switzerland, the Netherlands, Italy, Turkey and South Korea. The model coefficients are calculated: the growth rate and the expected number of infected pe...
32,846,910
Vaccines (Basel)
A Scalable Topical Vectored Vaccine Candidate against SARS-CoV-2.
The severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) caused an ongoing unprecedented global public health crises of coronavirus disease in 2019 (CoVID-19). The precipitously increased death rates, its impact on livelihood and trembling economies warrant the urgent development of a SARS-CoV-2 vaccine which w...
covid-19;sars-cov-2;newcastle disease virus;pandemic;recombinant vaccine
Journal Article
Rohaim, Mohammed A;Munir, Muhammad
10.3390/vaccines8030472
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: A Scalable Topical Vectored Vaccine Candidate against SARS-CoV-2. [Abstract]: The severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) caused an ongoing unprecedented global public health crises of coronavirus disease in 2019 (CoVID-19). The precipitously increased death rates, its impact on livelihood...
32,780,854
J Clin Endocrinol Metab
Is Subacute Thyroiditis an Underestimated Manifestation of SARS-CoV-2 Infection? Insights From a Case Series.
CONTEXT: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than 18 million people worldwide and the pandemic is still spreading. After the first case we reported, we observed 4 additional cases of subacute thyroiditis (SAT) related to SARS-CoV-2 infection. OBJECTIVES: The objective of this ...
covid-19;sars-cov-2;coronavirus;subacute thyroiditis;thyroid;virus
Case Reports;Journal Article
Brancatella, Alessandro;Ricci, Debora;Cappellani, Daniele;Viola, Nicola;Sgro, Daniele;Santini, Ferruccio;Latrofa, Francesco
10.1210/clinem/dgaa537
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Is Subacute Thyroiditis an Underestimated Manifestation of SARS-CoV-2 Infection? Insights From a Case Series. [Abstract]: CONTEXT: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than 18 million people worldwide and the pandemic is still spreading. After the first case we reporte...
32,648,781
Hum Factors
Disaster Ergonomics: Human Factors in COVID-19 Pandemic Emergency Management.
OBJECTIVE: We aimed to identify opportunities for application of human factors knowledge base to mitigate disaster management (DM) challenges associated with the unique characteristics of the COVID-19 pandemic. BACKGROUND: The role of DM is to minimize and prevent further spread of the contagion over an extended period...
communication;disasters;emergency response;pandemic;training
Journal Article;Research Support, U.S. Gov't, Non-P.H.S.;Review
Sasangohar, Farzan;Moats, Jason;Mehta, Ranjana;Peres, S Camille
10.1177/0018720820939428
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Disaster Ergonomics: Human Factors in COVID-19 Pandemic Emergency Management. [Abstract]: OBJECTIVE: We aimed to identify opportunities for application of human factors knowledge base to mitigate disaster management (DM) challenges associated with the unique characteristics of the COVID-19 pandemic. BACKGROUND...
32,885,740
J Biomol Struct Dyn
Identification of promising antiviral drug candidates against non-structural protein 15 (NSP15) from SARS-CoV-2: an in silico assisted drug-repurposing study.
The recent COVID-19 pandemic caused by SARS-CoV-2 has recorded a high number of infected people across the globe. The virulent nature of the virus makes it necessary for us to identify promising therapeutic agents in a time-sensitive manner. The current study utilises an in silico based drug repurposing approach to ide...
drug repurposing;md simulation;mm/pbsa;molecular docking;nsp15;sars-cov-2
Journal Article
Khan, Rameez Jabeer;Jha, Rajat Kumar;Singh, Ekampreet;Jain, Monika;Amera, Gizachew Muluneh;Singh, Rashmi Prabha;Muthukumaran, Jayaraman;Singh, Amit Kumar
10.1080/07391102.2020.1814870
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Identification of promising antiviral drug candidates against non-structural protein 15 (NSP15) from SARS-CoV-2: an in silico assisted drug-repurposing study. [Abstract]: The recent COVID-19 pandemic caused by SARS-CoV-2 has recorded a high number of infected people across the globe. The virulent nature of the...
32,766,284
Front Cardiovasc Med
Covid-19 Kills More Men Than Women: An Overview of Possible Reasons.
The high mortality observed in Covid-19 patients may be related to unrecognized pulmonary embolism, pulmonary thrombosis, or other underlying cardiovascular diseases. Recent data have highlighted that the mortality rate of Covid-19 seems to be higher in male patients compared to females. In this paper, we have analyzed...
covid-19;cardiovascular diseases;coagulation pattern;gender difference;immune system;mortality;sex hormones;smoking habit
Journal Article;Review
Capuano, Annalisa;Rossi, Francesco;Paolisso, Giuseppe
10.3389/fcvm.2020.00131
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Covid-19 Kills More Men Than Women: An Overview of Possible Reasons. [Abstract]: The high mortality observed in Covid-19 patients may be related to unrecognized pulmonary embolism, pulmonary thrombosis, or other underlying cardiovascular diseases. Recent data have highlighted that the mortality rate of Covid-1...
32,340,864
J Vasc Interv Radiol
COVID-19: What Should Interventional Radiologists Know and What Can They Do?
The outbreak of coronavirus disease 2019 (COVID-19) in late December 2019 in Wuhan, China, has been characterized as a "pandemic" by the World Health Organization and has resulted in 81,603 confirmed cases in China, among the 334,981 cases confirmed in 189 countries as of 09:00 am, March 24, 2020 (China central standar...
Editorial
Zhu, Hai-Dong;Zeng, Chu-Hui;Lu, Jian;Teng, Gao-Jun
10.1016/j.jvir.2020.03.022
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19: What Should Interventional Radiologists Know and What Can They Do? [Abstract]: The outbreak of coronavirus disease 2019 (COVID-19) in late December 2019 in Wuhan, China, has been characterized as a "pandemic" by the World Health Organization and has resulted in 81,603 confirmed cases in China, among ...
32,283,894
Turk J Med Sci
SARS-CoV-2 epidemiology and control, different scenarios for Turkey
Background/aim: Coronavirus Infectious Disease 2019 (COVID-19) is now a pandemic spreading in most countries including Turkey. Materials and methods: The current knowledge of COVID-19 and the virus causing it, SARS-CoV-2, was reviewed. The epidemiology and control in different countries was compared and the differences...
covid-19;coronavirus;control;epidemiology;mortality
Journal Article;Review
Petersen, Eskild;Gokengin, Deniz
10.3906/sag-2003-260
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: SARS-CoV-2 epidemiology and control, different scenarios for Turkey [Abstract]: Background/aim: Coronavirus Infectious Disease 2019 (COVID-19) is now a pandemic spreading in most countries including Turkey. Materials and methods: The current knowledge of COVID-19 and the virus causing it, SARS-CoV-2, was revie...
32,544,225
Hum Reprod
Delay in IVF treatment up to 180 days does not affect pregnancy outcomes in women with diminished ovarian reserve.
STUDY QUESTION: Will a delay in initiating IVF treatment affect pregnancy outcomes in infertile women with diminished ovarian reserve? SUMMARY ANSWER: A delay in IVF treatment up to 180 days does not affect the live birth rate for women with diminished ovarian reserve when compared to women who initiate IVF treatment w...
treatment delay / ivf / live birth outcomes / covid-19 / sars-cov-2 / coronavirus / outcomes / diminished ovarian reserve / treatment cycle suspension / cycle cancellation
Journal Article
Romanski, Phillip A;Bortoletto, Pietro;Rosenwaks, Zev;Schattman, Glenn L
10.1093/humrep/deaa137
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Delay in IVF treatment up to 180 days does not affect pregnancy outcomes in women with diminished ovarian reserve. [Abstract]: STUDY QUESTION: Will a delay in initiating IVF treatment affect pregnancy outcomes in infertile women with diminished ovarian reserve? SUMMARY ANSWER: A delay in IVF treatment up to 18...
32,827,400
Altern Ther Health Med
Repurposing Drugs for COVID-19: An Approach for Treatment in the Pandemic.
Context: Drug repurposing is a relevant approach during the COVID-19 pandemic, because development of new drugs is time-consuming and costly, and the safety of new drugs is paramount. Drug repurposing focuses on researching new indications for existing drugs and can reduce the challenges faced in drug development. Obje...
Journal Article;Review
Khadka, Sitaram;Yuchi, Alamgeer;Shrestha, Dhan Bahadur;Budhathoki, Pravash;Al-Subari, Saleh Musaed Mohammed;Ziad Alhouzani, Talal M;Anwar Butt, Imamah
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Repurposing Drugs for COVID-19: An Approach for Treatment in the Pandemic. [Abstract]: Context: Drug repurposing is a relevant approach during the COVID-19 pandemic, because development of new drugs is time-consuming and costly, and the safety of new drugs is paramount. Drug repurposing focuses on researching ...
32,383,371
J Korean Med Sci
Perspectives of Immune Therapy in Coronavirus Disease 2019.
The global fight against coronavirus disease 2019 (COVID-19) is largely based on strategies to boost immune responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and prevent its severe course and complications. The human defence may include antibodies which interact with SARS-CoV-2 and neutralize it...
antibodies;covid-19;comorbidities;convalescent serum;immunotherapy;vaccination
Journal Article;Review
Gasparyan, Armen Yuri;Misra, Durga Prasanna;Yessirkepov, Marlen;Zimba, Olena
10.3346/jkms.2020.35.e176
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Perspectives of Immune Therapy in Coronavirus Disease 2019. [Abstract]: The global fight against coronavirus disease 2019 (COVID-19) is largely based on strategies to boost immune responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and prevent its severe course and complications. The huma...
32,450,236
J Allergy Clin Immunol Pract
A Phased Approach to Resuming Suspended Allergy/Immunology Clinical Services.
In early 2020, the first US and Canadian cases of the novel severe acute respiratory syndrome coronavirus 2 infection were detected. In the ensuing months, there has been rapid spread of the infection. In March 2020, in response to the virus, state/provincial and local governments instituted shelter-in-place orders, an...
allergic rhinitis;allergy;angioedema;asthma;atopic dermatitis;covid-19;food allergy;immunotherapy;personal protective equipment;primary immunodeficiency;sars-cov-2;urticaria
Journal Article;Research Support, N.I.H., Extramural
Searing, Daniel A;Dutmer, Cullen M;Fleischer, David M;Shaker, Marcus S;Oppenheimer, John;Grayson, Mitchell H;Stukus, David;Hartog, Nicholas;Hsieh, Elena W Y;Rider, Nicholas L;Vander Leek, Timothy K;Kim, Harold;Chan, Edmond S;Mack, Doug;Ellis, Anne K;Abrams, Elissa M;Bansal, Priya;Lang, David M;Lieberman, Jay;Golden, Da...
10.1016/j.jaip.2020.05.012
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: A Phased Approach to Resuming Suspended Allergy/Immunology Clinical Services. [Abstract]: In early 2020, the first US and Canadian cases of the novel severe acute respiratory syndrome coronavirus 2 infection were detected. In the ensuing months, there has been rapid spread of the infection. In March 2020, in r...