row_id string | dataset_id string | source_dataset string | source_file string | source_table string | source_sha string | row_index int64 | split string | subject_type string | entry_id int64 | sequence_id int64 | target_sequence_id int64 | source_sequence_length int64 | target_sequence_length int64 | protein_id int64 | protein_name string | organism string | isoform int64 | protein_ids string | protein_names string | organisms string | isoforms string | uniprot_accessions string | interpro_accessions string | ec_numbers string | megascale_ids string | other_references string | mutations string | substitutions string | deletions string | insertions string | mutation_count int64 | substitution_count int64 | deletion_count int64 | insertion_count int64 | first_position int64 | first_source_aa string | first_target_aa string | conservation float64 | feature_types string | pdb_ids string | afdb_ids string | structure_ids string | structure_methods string | structure_resolution_min float64 | residue_positions string | residue_chain_names string | residue_secondary_structures string | residue_in_pocket_any bool | residue_in_tunnel_any bool | residue_asa_mean float64 | residue_bfactor_mean float64 | experiment_id int64 | experiment_dataset string | ph float64 | measure string | method string | buffer string | buffer_conc string | exp_temperature float64 | ion string | ion_conc string | pdb_chain_mutation string | tm float64 | dtm float64 | dg float64 | dg_text string | ddg float64 | dh float64 | dcp float64 | dhvh float64 | cm float64 | m_value float64 | trypsin_ml float64 | chymotrypsin_ml float64 | stabilizing float64 | stabilizing_text string | domainome_fitness float64 | domainome_fitness_std float64 | domainome_ddg float64 | domainome_ddg_std float64 | reversibility string | state string | measurement_types string | measurement_datasets string | annotation_types string | publication_id string | publication_type string | publication_title string | publication_year int64 | publication_doi string | publication_pmid string | publication_journal string | publication_url string | publication_author_count int64 | publication_authors string | annotations_json string | measurements_json string | features_json string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fireprotdb:12505 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,505 | train | mutant | 3,775,948 | 225 | 3,779,876 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L232P | L232P | 1 | 1 | 0 | 0 | 232 | L | P | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,809 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.662543 | 0.069555 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184300,"numValue":-0.662543073744852,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184301,"numValue":0.0695551884426569,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16896,"numValue":8.0,"position":232,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12506 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,506 | train | mutant | 3,775,949 | 225 | 3,779,877 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L232Q | L232Q | 1 | 1 | 0 | 0 | 232 | L | Q | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,829,161 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.387228 | 0.158272 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9651004,"numValue":0.387227630972329,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9651005,"numValue":0.158272295617738,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16896,"numValue":8.0,"position":232,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12507 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,507 | train | mutant | 3,775,949 | 225 | 3,779,877 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L232Q | L232Q | 1 | 1 | 0 | 0 | 232 | L | Q | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,810 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.22125 | 0.061496 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184302,"numValue":-0.221250416588585,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184303,"numValue":0.061496461826207,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16896,"numValue":8.0,"position":232,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12508 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,508 | train | mutant | 3,775,950 | 225 | 3,779,878 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L232R | L232R | 1 | 1 | 0 | 0 | 232 | L | R | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,829,162 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.71595 | 0.061073 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9651006,"numValue":0.715949896628008,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9651007,"numValue":0.0610729822648774,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16896,"numValue":8.0,"position":232,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12510 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,510 | train | mutant | 3,775,951 | 225 | 3,779,879 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L232S | L232S | 1 | 1 | 0 | 0 | 232 | L | S | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,829,163 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.606875 | 0.057885 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9651008,"numValue":0.606874870034307,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9651009,"numValue":0.0578847584220655,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16896,"numValue":8.0,"position":232,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12511 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,511 | train | mutant | 3,775,951 | 225 | 3,779,879 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L232S | L232S | 1 | 1 | 0 | 0 | 232 | L | S | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,812 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.279907 | 0.048288 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184306,"numValue":-0.279907107782521,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184307,"numValue":0.0482880997570189,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16896,"numValue":8.0,"position":232,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12512 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,512 | train | mutant | 3,775,952 | 225 | 3,779,880 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L232T | L232T | 1 | 1 | 0 | 0 | 232 | L | T | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,829,164 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.406784 | 0.078248 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9651010,"numValue":0.406784141808117,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9651011,"numValue":0.0782480200738001,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16896,"numValue":8.0,"position":232,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12513 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,513 | train | mutant | 3,775,952 | 225 | 3,779,880 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L232T | L232T | 1 | 1 | 0 | 0 | 232 | L | T | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,813 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.215186 | 0.0583 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184308,"numValue":-0.215185665777654,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184309,"numValue":0.0583001424090539,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16896,"numValue":8.0,"position":232,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12514 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,514 | train | mutant | 3,775,953 | 225 | 3,779,881 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L232V | L232V | 1 | 1 | 0 | 0 | 232 | L | V | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,829,165 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.196634 | 0.068264 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9651012,"numValue":0.196634057436938,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9651013,"numValue":0.0682644830869163,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16896,"numValue":8.0,"position":232,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12515 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,515 | train | mutant | 3,775,953 | 225 | 3,779,881 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L232V | L232V | 1 | 1 | 0 | 0 | 232 | L | V | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,814 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.161799 | 0.04513 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184310,"numValue":-0.161798830870885,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184311,"numValue":0.0451296790647575,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16896,"numValue":8.0,"position":232,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12516 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,516 | train | mutant | 3,775,954 | 225 | 3,779,882 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L232W | L232W | 1 | 1 | 0 | 0 | 232 | L | W | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,829,166 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.505439 | 0.054691 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9651014,"numValue":0.505438732209153,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9651015,"numValue":0.0546911276058396,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16896,"numValue":8.0,"position":232,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12517 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,517 | train | mutant | 3,775,954 | 225 | 3,779,882 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L232W | L232W | 1 | 1 | 0 | 0 | 232 | L | W | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,815 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.364746 | 0.054486 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184312,"numValue":-0.364745985467363,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184313,"numValue":0.0544863355582463,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16896,"numValue":8.0,"position":232,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12518 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,518 | train | mutant | 3,775,955 | 225 | 3,779,883 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L232Y | L232Y | 1 | 1 | 0 | 0 | 232 | L | Y | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,829,167 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.327003 | 0.099346 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9651016,"numValue":0.327002893121249,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9651017,"numValue":0.0993461653689409,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16896,"numValue":8.0,"position":232,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12519 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,519 | train | mutant | 3,775,955 | 225 | 3,779,883 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L232Y | L232Y | 1 | 1 | 0 | 0 | 232 | L | Y | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,816 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.073781 | 0.065564 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184314,"numValue":0.0737811707812066,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184315,"numValue":0.0655636721394598,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16896,"numValue":8.0,"position":232,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12520 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,520 | train | mutant | 4,906,039 | 225 | 4,912,627 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delL232 | delL232 | 1 | 0 | 1 | 0 | 232 | L | - | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,094,997 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.173022 | 0.074129 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182676,"numValue":-1.1730221248865,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182677,"numValue":0.0741288237494973,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16896,"numValue":8.0,"position":232,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12521 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,521 | train | mutant | 3,776,940 | 225 | 3,780,885 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P233A | P233A | 1 | 1 | 0 | 0 | 233 | P | A | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,830,156 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.288315 | 0.071358 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9652994,"numValue":0.288315092493105,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9652995,"numValue":0.0713578817818298,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12522 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,522 | train | mutant | 3,776,940 | 225 | 3,780,885 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P233A | P233A | 1 | 1 | 0 | 0 | 233 | P | A | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,008 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.218565 | 0.048432 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182698,"numValue":-0.218564962116413,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182699,"numValue":0.0484318173234674,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12523 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,523 | train | mutant | 3,776,941 | 225 | 3,780,886 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P233C | P233C | 1 | 1 | 0 | 0 | 233 | P | C | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,830,157 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.41903 | 0.067118 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9652996,"numValue":0.419030177026425,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9652997,"numValue":0.0671175273042086,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12524 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,524 | train | mutant | 3,776,941 | 225 | 3,780,886 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P233C | P233C | 1 | 1 | 0 | 0 | 233 | P | C | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,009 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.032604 | 0.052953 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182700,"numValue":-0.0326042022079107,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182701,"numValue":0.0529529848175981,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12525 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,525 | train | mutant | 3,776,942 | 225 | 3,780,887 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P233D | P233D | 1 | 1 | 0 | 0 | 233 | P | D | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,830,158 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.32859 | 0.10372 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9652998,"numValue":0.328589932653912,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9652999,"numValue":0.103720299959215,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12527 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,527 | train | mutant | 3,776,943 | 225 | 3,780,888 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P233E | P233E | 1 | 1 | 0 | 0 | 233 | P | E | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,830,159 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.318137 | 0.073451 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9653000,"numValue":0.318137493480208,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9653001,"numValue":0.0734507630884647,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12528 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,528 | train | mutant | 3,776,943 | 225 | 3,780,888 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P233E | P233E | 1 | 1 | 0 | 0 | 233 | P | E | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,011 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.167965 | 0.055029 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182704,"numValue":-0.167965430029205,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182705,"numValue":0.0550288451030378,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12529 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,529 | train | mutant | 3,776,944 | 225 | 3,780,889 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P233F | P233F | 1 | 1 | 0 | 0 | 233 | P | F | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,830,160 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.532118 | 0.07511 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9653002,"numValue":0.532118010600985,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9653003,"numValue":0.0751104001007963,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12530 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,530 | train | mutant | 3,776,944 | 225 | 3,780,889 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P233F | P233F | 1 | 1 | 0 | 0 | 233 | P | F | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,012 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.331457 | 0.085508 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182706,"numValue":-0.331457489675432,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182707,"numValue":0.0855081327238171,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12531 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,531 | train | mutant | 3,776,945 | 225 | 3,780,890 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P233G | P233G | 1 | 1 | 0 | 0 | 233 | P | G | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,830,161 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.276883 | 0.081784 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9653004,"numValue":0.276883141544592,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9653005,"numValue":0.0817836900642089,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12533 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,533 | train | mutant | 3,776,946 | 225 | 3,780,891 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P233H | P233H | 1 | 1 | 0 | 0 | 233 | P | H | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,830,162 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.527153 | 0.122677 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9653006,"numValue":0.527153463771197,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9653007,"numValue":0.12267712624312,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12534 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,534 | train | mutant | 3,776,946 | 225 | 3,780,891 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P233H | P233H | 1 | 1 | 0 | 0 | 233 | P | H | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,014 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.175622 | 0.071515 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182710,"numValue":-0.175621561268089,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182711,"numValue":0.0715154667676143,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12535 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,535 | train | mutant | 3,776,947 | 225 | 3,780,892 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P233I | P233I | 1 | 1 | 0 | 0 | 233 | P | I | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,830,163 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.556989 | 0.17046 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9653008,"numValue":0.556988794232708,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9653009,"numValue":0.170459523670466,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12536 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,536 | train | mutant | 3,776,947 | 225 | 3,780,892 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P233I | P233I | 1 | 1 | 0 | 0 | 233 | P | I | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,015 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.299585 | 0.080176 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182712,"numValue":-0.299584526774166,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182713,"numValue":0.0801760534619162,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12537 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,537 | train | mutant | 3,776,948 | 225 | 3,780,893 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P233K | P233K | 1 | 1 | 0 | 0 | 233 | P | K | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,830,164 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.322278 | 0.145768 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9653010,"numValue":0.322278121087519,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9653011,"numValue":0.145767828450572,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12539 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,539 | train | mutant | 3,776,949 | 225 | 3,780,894 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P233L | P233L | 1 | 1 | 0 | 0 | 233 | P | L | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,830,165 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.404711 | 0.085428 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9653012,"numValue":0.404711453662338,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9653013,"numValue":0.0854279406329038,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12541 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,541 | train | mutant | 3,776,950 | 225 | 3,780,895 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P233M | P233M | 1 | 1 | 0 | 0 | 233 | P | M | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,830,166 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.244138 | 0.083203 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9653014,"numValue":0.244138285493224,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9653015,"numValue":0.0832025474048827,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12542 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,542 | train | mutant | 3,776,950 | 225 | 3,780,895 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P233M | P233M | 1 | 1 | 0 | 0 | 233 | P | M | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,018 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.169123 | 0.057531 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182718,"numValue":-0.169123159290541,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182719,"numValue":0.0575312669552882,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12543 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,543 | train | mutant | 3,776,951 | 225 | 3,780,896 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P233N | P233N | 1 | 1 | 0 | 0 | 233 | P | N | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,830,167 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.450955 | 0.049442 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9653016,"numValue":0.450955018579092,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9653017,"numValue":0.0494421897284038,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12544 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,544 | train | mutant | 3,776,951 | 225 | 3,780,896 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P233N | P233N | 1 | 1 | 0 | 0 | 233 | P | N | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,019 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.085574 | 0.089949 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182720,"numValue":-0.0855740954425558,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182721,"numValue":0.0899494367911711,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12546 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,546 | train | mutant | 3,776,952 | 225 | 3,780,897 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P233Q | P233Q | 1 | 1 | 0 | 0 | 233 | P | Q | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,800 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.251467 | 0.053311 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184282,"numValue":-0.251466752464351,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184283,"numValue":0.0533105123014443,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12547 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,547 | train | mutant | 3,776,953 | 225 | 3,780,898 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P233R | P233R | 1 | 1 | 0 | 0 | 233 | P | R | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,830,169 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.487496 | 0.09962 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9653020,"numValue":0.487495761264801,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9653021,"numValue":0.0996200811792298,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12548 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,548 | train | mutant | 3,776,953 | 225 | 3,780,898 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P233R | P233R | 1 | 1 | 0 | 0 | 233 | P | R | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,801 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.184255 | 0.043004 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184284,"numValue":-0.184254800089736,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184285,"numValue":0.0430042791065957,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12549 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,549 | train | mutant | 3,776,954 | 225 | 3,780,899 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P233S | P233S | 1 | 1 | 0 | 0 | 233 | P | S | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,830,170 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.426879 | 0.066292 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9653022,"numValue":0.426879256963338,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9653023,"numValue":0.0662915949546891,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12550 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,550 | train | mutant | 3,776,954 | 225 | 3,780,899 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P233S | P233S | 1 | 1 | 0 | 0 | 233 | P | S | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,802 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.119961 | 0.047531 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184286,"numValue":-0.119960643729774,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184287,"numValue":0.0475310482598329,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12551 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,551 | train | mutant | 3,776,955 | 225 | 3,780,900 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P233T | P233T | 1 | 1 | 0 | 0 | 233 | P | T | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,830,171 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.436271 | 0.071211 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9653024,"numValue":0.436271456730033,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9653025,"numValue":0.0712107063285897,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12552 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,552 | train | mutant | 3,776,955 | 225 | 3,780,900 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P233T | P233T | 1 | 1 | 0 | 0 | 233 | P | T | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,803 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.024303 | 0.052326 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184288,"numValue":-0.0243027662054912,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184289,"numValue":0.0523257103943117,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12553 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,553 | train | mutant | 3,776,956 | 225 | 3,780,901 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P233V | P233V | 1 | 1 | 0 | 0 | 233 | P | V | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,830,172 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.610106 | 0.113562 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9653026,"numValue":0.610105730760086,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9653027,"numValue":0.113562053837625,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12554 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,554 | train | mutant | 3,776,956 | 225 | 3,780,901 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P233V | P233V | 1 | 1 | 0 | 0 | 233 | P | V | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,804 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.14706 | 0.051545 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184290,"numValue":-0.147060261037394,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184291,"numValue":0.0515445892681529,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12556 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,556 | train | mutant | 3,776,957 | 225 | 3,780,902 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P233W | P233W | 1 | 1 | 0 | 0 | 233 | P | W | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,805 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.326562 | 0.049352 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184292,"numValue":-0.326562403479047,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184293,"numValue":0.0493522240215828,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12557 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,557 | train | mutant | 3,776,958 | 225 | 3,780,903 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P233Y | P233Y | 1 | 1 | 0 | 0 | 233 | P | Y | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,830,174 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.480087 | 0.112578 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9653030,"numValue":0.480086508513861,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9653031,"numValue":0.112578002680765,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12558 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,558 | train | mutant | 3,776,958 | 225 | 3,780,903 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P233Y | P233Y | 1 | 1 | 0 | 0 | 233 | P | Y | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,806 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.238399 | 0.069739 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184294,"numValue":-0.238399132080211,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184295,"numValue":0.069739072451107,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12559 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,559 | train | mutant | 4,906,040 | 225 | 4,912,628 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delP233 | delP233 | 1 | 0 | 1 | 0 | 233 | P | - | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,007 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.286119 | 0.078256 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182696,"numValue":-1.28611858784736,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182697,"numValue":0.0782557426564069,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16897,"numValue":8.0,"position":233,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12560 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,560 | train | mutant | 3,777,982 | 225 | 3,781,927 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234A | D234A | 1 | 1 | 0 | 0 | 234 | D | A | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,831,200 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.085135 | 0.097288 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9655082,"numValue":-0.0851349569423858,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9655083,"numValue":0.0972884772139236,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12561 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,561 | train | mutant | 3,777,982 | 225 | 3,781,927 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234A | D234A | 1 | 1 | 0 | 0 | 234 | D | A | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,021 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.120054 | 0.051864 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182724,"numValue":-0.12005373948481,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182725,"numValue":0.0518643453375416,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12562 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,562 | train | mutant | 3,777,983 | 225 | 3,781,928 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234C | D234C | 1 | 1 | 0 | 0 | 234 | D | C | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,831,201 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.073757 | 0.089179 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9655084,"numValue":0.073757189381356,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9655085,"numValue":0.0891793561768556,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12563 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,563 | train | mutant | 3,777,983 | 225 | 3,781,928 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234C | D234C | 1 | 1 | 0 | 0 | 234 | D | C | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,022 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.148115 | 0.054943 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182726,"numValue":-0.148115346261127,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182727,"numValue":0.0549430299134604,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12564 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,564 | train | mutant | 3,777,984 | 225 | 3,781,929 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234E | D234E | 1 | 1 | 0 | 0 | 234 | D | E | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,831,202 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.193464 | 0.063466 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9655086,"numValue":-0.193464186921157,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9655087,"numValue":0.063465577565462,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12565 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,565 | train | mutant | 3,777,984 | 225 | 3,781,929 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234E | D234E | 1 | 1 | 0 | 0 | 234 | D | E | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,783 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.06676 | 0.056783 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184248,"numValue":-0.0667600003330758,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184249,"numValue":0.0567831192315965,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12566 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,566 | train | mutant | 3,777,985 | 225 | 3,781,930 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234F | D234F | 1 | 1 | 0 | 0 | 234 | D | F | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,831,203 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.007665 | 0.082812 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9655088,"numValue":0.00766470439405678,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9655089,"numValue":0.0828119444946688,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12567 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,567 | train | mutant | 3,777,985 | 225 | 3,781,930 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234F | D234F | 1 | 1 | 0 | 0 | 234 | D | F | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,784 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.120616 | 0.06817 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184250,"numValue":-0.120616292466091,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184251,"numValue":0.0681701066164812,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12568 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,568 | train | mutant | 3,777,986 | 225 | 3,781,931 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234G | D234G | 1 | 1 | 0 | 0 | 234 | D | G | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,831,204 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.018334 | 0.081411 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9655090,"numValue":-0.018334276029677,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9655091,"numValue":0.0814105942699941,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12569 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,569 | train | mutant | 3,777,986 | 225 | 3,781,931 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234G | D234G | 1 | 1 | 0 | 0 | 234 | D | G | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,785 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.074631 | 0.045666 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184252,"numValue":-0.0746309679297336,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184253,"numValue":0.0456656400790879,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12570 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,570 | train | mutant | 3,777,987 | 225 | 3,781,932 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234H | D234H | 1 | 1 | 0 | 0 | 234 | D | H | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,831,205 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.140922 | 0.100942 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9655092,"numValue":-0.140921773670836,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9655093,"numValue":0.100942420949942,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12571 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,571 | train | mutant | 3,777,987 | 225 | 3,781,932 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234H | D234H | 1 | 1 | 0 | 0 | 234 | D | H | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,786 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.118052 | 0.074987 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184254,"numValue":-0.118051782906444,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184255,"numValue":0.0749872541368461,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12572 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,572 | train | mutant | 3,777,988 | 225 | 3,781,933 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234I | D234I | 1 | 1 | 0 | 0 | 234 | D | I | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,831,206 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.007831 | 0.076722 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9655094,"numValue":0.00783106869519325,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9655095,"numValue":0.0767220045095531,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12573 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,573 | train | mutant | 3,777,988 | 225 | 3,781,933 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234I | D234I | 1 | 1 | 0 | 0 | 234 | D | I | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,787 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.309787 | 0.081977 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184256,"numValue":-0.309786866697776,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184257,"numValue":0.0819774165373382,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12574 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,574 | train | mutant | 3,777,989 | 225 | 3,781,934 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234K | D234K | 1 | 1 | 0 | 0 | 234 | D | K | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,831,207 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.113344 | 0.089958 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9655096,"numValue":-0.113343834917263,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9655097,"numValue":0.0899581291405671,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12575 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,575 | train | mutant | 3,777,989 | 225 | 3,781,934 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234K | D234K | 1 | 1 | 0 | 0 | 234 | D | K | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,788 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.209221 | 0.059519 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184258,"numValue":-0.209221171933684,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184259,"numValue":0.0595188851959978,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12576 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,576 | train | mutant | 3,777,990 | 225 | 3,781,935 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234L | D234L | 1 | 1 | 0 | 0 | 234 | D | L | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,831,208 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.023966 | 0.082774 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9655098,"numValue":-0.0239656236490795,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9655099,"numValue":0.0827743376161056,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12577 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,577 | train | mutant | 3,777,990 | 225 | 3,781,935 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234L | D234L | 1 | 1 | 0 | 0 | 234 | D | L | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,789 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.111288 | 0.047361 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184260,"numValue":-0.111287620397428,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184261,"numValue":0.0473613116233873,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12578 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,578 | train | mutant | 3,777,991 | 225 | 3,781,936 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234M | D234M | 1 | 1 | 0 | 0 | 234 | D | M | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,831,209 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.026721 | 0.091088 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9655100,"numValue":0.0267210488087164,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9655101,"numValue":0.0910882709801422,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12579 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,579 | train | mutant | 3,777,991 | 225 | 3,781,936 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234M | D234M | 1 | 1 | 0 | 0 | 234 | D | M | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,790 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.171726 | 0.062956 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184262,"numValue":-0.171725861980459,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184263,"numValue":0.0629555985405975,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12582 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,582 | train | mutant | 3,777,993 | 225 | 3,781,938 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234P | D234P | 1 | 1 | 0 | 0 | 234 | D | P | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,831,211 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.167901 | 0.096478 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9655104,"numValue":-0.167901085636316,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9655105,"numValue":0.0964776292512126,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12583 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,583 | train | mutant | 3,777,993 | 225 | 3,781,938 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234P | D234P | 1 | 1 | 0 | 0 | 234 | D | P | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,792 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.214169 | 0.06042 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184266,"numValue":-0.214168773684192,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184267,"numValue":0.0604200202771307,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12585 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,585 | train | mutant | 3,777,994 | 225 | 3,781,939 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234Q | D234Q | 1 | 1 | 0 | 0 | 234 | D | Q | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,793 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.191188 | 0.06164 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184268,"numValue":-0.191187648924116,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184269,"numValue":0.0616404897118389,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12586 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,586 | train | mutant | 3,777,995 | 225 | 3,781,940 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234R | D234R | 1 | 1 | 0 | 0 | 234 | D | R | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,831,213 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.091394 | 0.068734 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9655108,"numValue":-0.0913938971985074,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9655109,"numValue":0.0687343305094633,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12587 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,587 | train | mutant | 3,777,995 | 225 | 3,781,940 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234R | D234R | 1 | 1 | 0 | 0 | 234 | D | R | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,794 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.209092 | 0.043801 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184270,"numValue":-0.20909227011902,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184271,"numValue":0.0438012105973062,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12588 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,588 | train | mutant | 3,777,996 | 225 | 3,781,941 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234S | D234S | 1 | 1 | 0 | 0 | 234 | D | S | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,831,214 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.109479 | 0.085676 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9655110,"numValue":-0.109478552226638,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9655111,"numValue":0.0856756374045774,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12589 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,589 | train | mutant | 3,777,996 | 225 | 3,781,941 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234S | D234S | 1 | 1 | 0 | 0 | 234 | D | S | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,795 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.100827 | 0.046779 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184272,"numValue":-0.100826681154276,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184273,"numValue":0.0467791687490377,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12590 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,590 | train | mutant | 3,777,997 | 225 | 3,781,942 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234T | D234T | 1 | 1 | 0 | 0 | 234 | D | T | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,831,215 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.08762 | 0.081981 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9655112,"numValue":-0.087619593446597,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9655113,"numValue":0.0819805083976014,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12591 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,591 | train | mutant | 3,777,997 | 225 | 3,781,942 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234T | D234T | 1 | 1 | 0 | 0 | 234 | D | T | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,796 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.074762 | 0.05853 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184274,"numValue":-0.0747622568150398,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184275,"numValue":0.0585295398977434,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12592 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,592 | train | mutant | 3,777,998 | 225 | 3,781,943 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234V | D234V | 1 | 1 | 0 | 0 | 234 | D | V | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,831,216 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.076633 | 0.056725 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9655114,"numValue":-0.0766325446996855,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9655115,"numValue":0.0567247325048722,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12593 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,593 | train | mutant | 3,777,998 | 225 | 3,781,943 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234V | D234V | 1 | 1 | 0 | 0 | 234 | D | V | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,797 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.196366 | 0.05013 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184276,"numValue":-0.196366000836676,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184277,"numValue":0.0501296213175402,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12594 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,594 | train | mutant | 3,777,999 | 225 | 3,781,944 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234W | D234W | 1 | 1 | 0 | 0 | 234 | D | W | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,831,217 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.100627 | 0.092378 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9655116,"numValue":0.100626926020475,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9655117,"numValue":0.0923781745367732,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12595 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,595 | train | mutant | 3,777,999 | 225 | 3,781,944 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234W | D234W | 1 | 1 | 0 | 0 | 234 | D | W | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,798 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.30665 | 0.048799 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184278,"numValue":-0.30665025587428,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184279,"numValue":0.0487985191154807,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12596 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,596 | train | mutant | 3,778,000 | 225 | 3,781,945 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234Y | D234Y | 1 | 1 | 0 | 0 | 234 | D | Y | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,831,218 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.047823 | 0.073237 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9655118,"numValue":0.0478233959017194,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9655119,"numValue":0.0732374323871478,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12597 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,597 | train | mutant | 3,778,000 | 225 | 3,781,945 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D234Y | D234Y | 1 | 1 | 0 | 0 | 234 | D | Y | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,799 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.194502 | 0.058298 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184280,"numValue":-0.194502494355543,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184281,"numValue":0.0582978110367269,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12598 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,598 | train | mutant | 4,906,041 | 225 | 4,912,629 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delD234 | delD234 | 1 | 0 | 1 | 0 | 234 | D | - | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,020 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.266324 | 0.093004 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182722,"numValue":-1.26632382841986,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182723,"numValue":0.0930043302296919,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16898,"numValue":3.0,"position":234,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12599 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,599 | train | mutant | 3,779,177 | 225 | 3,783,122 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235A | G235A | 1 | 1 | 0 | 0 | 235 | G | A | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,832,397 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.250238 | 0.047043 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9657476,"numValue":0.250238026672603,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9657477,"numValue":0.0470429136367351,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12600 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,600 | train | mutant | 3,779,177 | 225 | 3,783,122 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235A | G235A | 1 | 1 | 0 | 0 | 235 | G | A | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,024 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.315937 | 0.048049 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182730,"numValue":-0.315936756361602,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182731,"numValue":0.0480491380719574,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12601 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,601 | train | mutant | 3,779,178 | 225 | 3,783,123 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235C | G235C | 1 | 1 | 0 | 0 | 235 | G | C | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,832,398 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.282199 | 0.095131 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9657478,"numValue":0.282198730918861,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9657479,"numValue":0.0951311004481369,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12602 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,602 | train | mutant | 3,779,178 | 225 | 3,783,123 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235C | G235C | 1 | 1 | 0 | 0 | 235 | G | C | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,025 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.188561 | 0.052118 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182732,"numValue":-0.188561075527778,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182733,"numValue":0.0521184330935708,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12603 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,603 | train | mutant | 3,779,179 | 225 | 3,783,124 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235D | G235D | 1 | 1 | 0 | 0 | 235 | G | D | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,832,399 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.117655 | 0.074148 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9657480,"numValue":0.117654616208222,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9657481,"numValue":0.0741478800634587,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12604 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,604 | train | mutant | 3,779,179 | 225 | 3,783,124 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235D | G235D | 1 | 1 | 0 | 0 | 235 | G | D | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,026 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.022364 | 0.046447 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182734,"numValue":-0.0223636691540301,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182735,"numValue":0.0464473579729073,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12605 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,605 | train | mutant | 3,779,180 | 225 | 3,783,125 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235E | G235E | 1 | 1 | 0 | 0 | 235 | G | E | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,832,400 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.196975 | 0.095593 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9657482,"numValue":0.196974859927712,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9657483,"numValue":0.0955934557522677,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12606 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,606 | train | mutant | 3,779,180 | 225 | 3,783,125 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235E | G235E | 1 | 1 | 0 | 0 | 235 | G | E | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,027 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.130854 | 0.050071 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182736,"numValue":-0.13085443844933,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182737,"numValue":0.0500714165783878,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12607 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,607 | train | mutant | 3,779,181 | 225 | 3,783,126 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235F | G235F | 1 | 1 | 0 | 0 | 235 | G | F | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,832,401 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.145114 | 0.123695 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9657484,"numValue":0.145114006647712,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9657485,"numValue":0.123694588107084,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12608 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,608 | train | mutant | 3,779,181 | 225 | 3,783,126 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235F | G235F | 1 | 1 | 0 | 0 | 235 | G | F | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,028 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.0906 | 0.070073 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182738,"numValue":-0.0905996748340328,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182739,"numValue":0.070072681487121,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12609 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,609 | train | mutant | 3,779,182 | 225 | 3,783,127 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235H | G235H | 1 | 1 | 0 | 0 | 235 | G | H | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,832,402 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.042609 | 0.110274 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9657486,"numValue":0.0426093777327088,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9657487,"numValue":0.11027377679312,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12610 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,610 | train | mutant | 3,779,182 | 225 | 3,783,127 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235H | G235H | 1 | 1 | 0 | 0 | 235 | G | H | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,769 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.232376 | 0.07159 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184220,"numValue":-0.232375757160407,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184221,"numValue":0.0715902139063153,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12611 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,611 | train | mutant | 3,779,183 | 225 | 3,783,128 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235I | G235I | 1 | 1 | 0 | 0 | 235 | G | I | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,832,403 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.644689 | 0.065404 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9657488,"numValue":0.644689295356406,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9657489,"numValue":0.0654038014279663,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12612 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,612 | train | mutant | 3,779,183 | 225 | 3,783,128 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235I | G235I | 1 | 1 | 0 | 0 | 235 | G | I | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,770 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.492254 | 0.06045 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184222,"numValue":-0.492253512169642,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184223,"numValue":0.0604500734965126,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12614 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,614 | train | mutant | 3,779,184 | 225 | 3,783,129 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235K | G235K | 1 | 1 | 0 | 0 | 235 | G | K | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,771 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.293641 | 0.055651 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184224,"numValue":-0.29364072087576,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184225,"numValue":0.0556510111951505,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12615 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,615 | train | mutant | 3,779,185 | 225 | 3,783,130 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235L | G235L | 1 | 1 | 0 | 0 | 235 | G | L | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,832,405 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.380318 | 0.093156 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9657492,"numValue":0.380318025325507,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9657493,"numValue":0.0931555802845226,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] |
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