row_id string | dataset_id string | source_dataset string | source_file string | source_table string | source_sha string | row_index int64 | split string | subject_type string | entry_id int64 | sequence_id int64 | target_sequence_id int64 | source_sequence_length int64 | target_sequence_length int64 | protein_id int64 | protein_name string | organism string | isoform int64 | protein_ids string | protein_names string | organisms string | isoforms string | uniprot_accessions string | interpro_accessions string | ec_numbers string | megascale_ids string | other_references string | mutations string | substitutions string | deletions string | insertions string | mutation_count int64 | substitution_count int64 | deletion_count int64 | insertion_count int64 | first_position int64 | first_source_aa string | first_target_aa string | conservation float64 | feature_types string | pdb_ids string | afdb_ids string | structure_ids string | structure_methods string | structure_resolution_min float64 | residue_positions string | residue_chain_names string | residue_secondary_structures string | residue_in_pocket_any bool | residue_in_tunnel_any bool | residue_asa_mean float64 | residue_bfactor_mean float64 | experiment_id int64 | experiment_dataset string | ph float64 | measure string | method string | buffer string | buffer_conc string | exp_temperature float64 | ion string | ion_conc string | pdb_chain_mutation string | tm float64 | dtm float64 | dg float64 | dg_text string | ddg float64 | dh float64 | dcp float64 | dhvh float64 | cm float64 | m_value float64 | trypsin_ml float64 | chymotrypsin_ml float64 | stabilizing float64 | stabilizing_text string | domainome_fitness float64 | domainome_fitness_std float64 | domainome_ddg float64 | domainome_ddg_std float64 | reversibility string | state string | measurement_types string | measurement_datasets string | annotation_types string | publication_id string | publication_type string | publication_title string | publication_year int64 | publication_doi string | publication_pmid string | publication_journal string | publication_url string | publication_author_count int64 | publication_authors string | annotations_json string | measurements_json string | features_json string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fireprotdb:12616 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,616 | train | mutant | 3,779,185 | 225 | 3,783,130 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235L | G235L | 1 | 1 | 0 | 0 | 235 | G | L | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,772 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.290191 | 0.046244 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184226,"numValue":-0.290190608107957,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184227,"numValue":0.0462442819164961,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12617 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,617 | train | mutant | 3,779,186 | 225 | 3,783,131 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235M | G235M | 1 | 1 | 0 | 0 | 235 | G | M | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,832,406 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.284927 | 0.062017 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9657494,"numValue":0.284927390153498,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9657495,"numValue":0.0620174392975861,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12618 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,618 | train | mutant | 3,779,186 | 225 | 3,783,131 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235M | G235M | 1 | 1 | 0 | 0 | 235 | G | M | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,773 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.136846 | 0.0547 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184228,"numValue":-0.136845985760575,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184229,"numValue":0.0546995327941792,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12619 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,619 | train | mutant | 3,779,187 | 225 | 3,783,132 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235N | G235N | 1 | 1 | 0 | 0 | 235 | G | N | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,832,407 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.070347 | 0.103461 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9657496,"numValue":-0.0703468396438444,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9657497,"numValue":0.103460945280243,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12621 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,621 | train | mutant | 3,779,188 | 225 | 3,783,133 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235P | G235P | 1 | 1 | 0 | 0 | 235 | G | P | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,832,408 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.333205 | 0.099236 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9657498,"numValue":0.333205012332097,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9657499,"numValue":0.0992362141988508,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12622 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,622 | train | mutant | 3,779,188 | 225 | 3,783,133 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235P | G235P | 1 | 1 | 0 | 0 | 235 | G | P | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,775 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.308249 | 0.053007 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184232,"numValue":-0.308248797514159,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184233,"numValue":0.0530065268120966,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12623 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,623 | train | mutant | 3,779,189 | 225 | 3,783,134 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235Q | G235Q | 1 | 1 | 0 | 0 | 235 | G | Q | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,832,409 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.168878 | 0.059414 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9657500,"numValue":0.168877750451138,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9657501,"numValue":0.0594137593558166,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12626 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,626 | train | mutant | 3,779,190 | 225 | 3,783,135 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235R | G235R | 1 | 1 | 0 | 0 | 235 | G | R | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,777 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.288404 | 0.044964 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184236,"numValue":-0.288404283577579,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184237,"numValue":0.0449639765776968,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12627 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,627 | train | mutant | 3,779,191 | 225 | 3,783,136 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235S | G235S | 1 | 1 | 0 | 0 | 235 | G | S | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,832,411 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.209074 | 0.078867 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9657504,"numValue":0.209073787209618,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9657505,"numValue":0.0788672282445654,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12628 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,628 | train | mutant | 3,779,191 | 225 | 3,783,136 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235S | G235S | 1 | 1 | 0 | 0 | 235 | G | S | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,778 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.152065 | 0.045122 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184238,"numValue":-0.152065152483308,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184239,"numValue":0.0451217142057156,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12629 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,629 | train | mutant | 3,779,192 | 225 | 3,783,137 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235T | G235T | 1 | 1 | 0 | 0 | 235 | G | T | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,832,412 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.369949 | 0.136137 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9657506,"numValue":0.369949171996796,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9657507,"numValue":0.136136967915641,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12630 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,630 | train | mutant | 3,779,192 | 225 | 3,783,137 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235T | G235T | 1 | 1 | 0 | 0 | 235 | G | T | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,779 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.19044 | 0.050091 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184240,"numValue":-0.190439700122978,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184241,"numValue":0.0500910382990645,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12631 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,631 | train | mutant | 3,779,193 | 225 | 3,783,138 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235V | G235V | 1 | 1 | 0 | 0 | 235 | G | V | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,832,413 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.665481 | 0.098659 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9657508,"numValue":0.66548061038291,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9657509,"numValue":0.0986586582905038,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12632 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,632 | train | mutant | 3,779,193 | 225 | 3,783,138 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235V | G235V | 1 | 1 | 0 | 0 | 235 | G | V | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,780 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.451692 | 0.045501 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184242,"numValue":-0.451692248683921,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184243,"numValue":0.0455010356445226,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12633 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,633 | train | mutant | 3,779,194 | 225 | 3,783,139 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235W | G235W | 1 | 1 | 0 | 0 | 235 | G | W | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,832,414 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.376986 | 0.089359 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9657510,"numValue":0.37698602437695,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9657511,"numValue":0.0893589734705797,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12635 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,635 | train | mutant | 3,779,195 | 225 | 3,783,140 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235Y | G235Y | 1 | 1 | 0 | 0 | 235 | G | Y | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,832,415 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.262761 | 0.083925 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9657512,"numValue":0.262761015958894,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9657513,"numValue":0.0839245544620711,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12636 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,636 | train | mutant | 3,779,195 | 225 | 3,783,140 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G235Y | G235Y | 1 | 1 | 0 | 0 | 235 | G | Y | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,782 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.151888 | 0.062034 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184246,"numValue":-0.151887713565591,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184247,"numValue":0.0620342131435189,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12637 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,637 | train | mutant | 4,906,042 | 225 | 4,912,630 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delG235 | delG235 | 1 | 0 | 1 | 0 | 235 | G | - | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,023 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.240426 | 0.078379 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182728,"numValue":-1.24042575107676,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182729,"numValue":0.0783786051823471,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16899,"numValue":4.0,"position":235,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12638 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,638 | train | mutant | 3,780,430 | 225 | 3,784,375 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236A | W236A | 1 | 1 | 0 | 0 | 236 | W | A | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,833,651 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.4965 | 0.068278 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9659984,"numValue":0.49650018932734,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9659985,"numValue":0.0682775914809433,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12639 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,639 | train | mutant | 3,780,430 | 225 | 3,784,375 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236A | W236A | 1 | 1 | 0 | 0 | 236 | W | A | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,030 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.784568 | 0.052373 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182742,"numValue":-0.784567976596746,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182743,"numValue":0.0523733881519332,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12640 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,640 | train | mutant | 3,780,431 | 225 | 3,784,376 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236C | W236C | 1 | 1 | 0 | 0 | 236 | W | C | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,833,652 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.431262 | 0.070234 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9659986,"numValue":0.431261684871836,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9659987,"numValue":0.0702337995784325,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12641 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,641 | train | mutant | 3,780,431 | 225 | 3,784,376 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236C | W236C | 1 | 1 | 0 | 0 | 236 | W | C | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,031 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.417914 | 0.052303 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182744,"numValue":-0.417914005565288,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182745,"numValue":0.0523027308609321,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12642 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,642 | train | mutant | 3,780,432 | 225 | 3,784,377 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236D | W236D | 1 | 1 | 0 | 0 | 236 | W | D | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,833,653 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.593719 | 0.07041 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9659988,"numValue":0.593718842878342,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9659989,"numValue":0.0704098216005525,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12643 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,643 | train | mutant | 3,780,432 | 225 | 3,784,377 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236D | W236D | 1 | 1 | 0 | 0 | 236 | W | D | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,032 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.683126 | 0.062954 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182746,"numValue":-0.683125510785873,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182747,"numValue":0.0629539832894632,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12645 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,645 | train | mutant | 3,780,433 | 225 | 3,784,378 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236E | W236E | 1 | 1 | 0 | 0 | 236 | W | E | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,033 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.689594 | 0.0801 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182748,"numValue":-0.689593756104312,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182749,"numValue":0.0801000650464815,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12648 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,648 | train | mutant | 3,780,435 | 225 | 3,784,380 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236G | W236G | 1 | 1 | 0 | 0 | 236 | W | G | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,833,656 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.594304 | 0.063822 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9659994,"numValue":0.594304360147127,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9659995,"numValue":0.0638215623424586,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12649 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,649 | train | mutant | 3,780,435 | 225 | 3,784,380 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236G | W236G | 1 | 1 | 0 | 0 | 236 | W | G | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,035 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.747993 | 0.063452 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182752,"numValue":-0.74799264366892,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182753,"numValue":0.0634517591304248,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12650 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,650 | train | mutant | 3,780,436 | 225 | 3,784,381 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236H | W236H | 1 | 1 | 0 | 0 | 236 | W | H | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,833,657 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.536168 | 0.060888 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9659996,"numValue":0.536168424460408,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9659997,"numValue":0.0608877126865626,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12652 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,652 | train | mutant | 3,780,437 | 225 | 3,784,382 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236I | W236I | 1 | 1 | 0 | 0 | 236 | W | I | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,833,658 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.334047 | 0.090348 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9659998,"numValue":0.334047228617573,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9659999,"numValue":0.0903478475802079,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12653 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,653 | train | mutant | 3,780,437 | 225 | 3,784,382 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236I | W236I | 1 | 1 | 0 | 0 | 236 | W | I | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,037 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.350541 | 0.048395 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182756,"numValue":-0.35054132376745,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182757,"numValue":0.0483952235305266,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12654 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,654 | train | mutant | 3,780,438 | 225 | 3,784,383 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236K | W236K | 1 | 1 | 0 | 0 | 236 | W | K | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,833,659 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.497979 | 0.084174 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9660000,"numValue":0.497979156908561,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9660001,"numValue":0.0841740741883609,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12655 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,655 | train | mutant | 3,780,438 | 225 | 3,784,383 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236K | W236K | 1 | 1 | 0 | 0 | 236 | W | K | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,038 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.019701 | 0.094249 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182758,"numValue":-1.01970103905565,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182759,"numValue":0.0942487897243516,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12656 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,656 | train | mutant | 3,780,439 | 225 | 3,784,384 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236L | W236L | 1 | 1 | 0 | 0 | 236 | W | L | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,833,660 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.541609 | 0.067363 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9660002,"numValue":0.54160893123711,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9660003,"numValue":0.0673632998460096,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12657 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,657 | train | mutant | 3,780,439 | 225 | 3,784,384 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236L | W236L | 1 | 1 | 0 | 0 | 236 | W | L | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,039 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.774856 | 0.046172 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182760,"numValue":-0.774856100121031,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182761,"numValue":0.046172144641697,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12658 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,658 | train | mutant | 3,780,440 | 225 | 3,784,385 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236M | W236M | 1 | 1 | 0 | 0 | 236 | W | M | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,833,661 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.491692 | 0.062368 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9660004,"numValue":0.491692157779999,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9660005,"numValue":0.062367533230499,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12659 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,659 | train | mutant | 3,780,440 | 225 | 3,784,385 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236M | W236M | 1 | 1 | 0 | 0 | 236 | W | M | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,040 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.500799 | 0.062821 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182762,"numValue":-0.500798986360688,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182763,"numValue":0.0628213894722061,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12661 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,661 | train | mutant | 3,780,441 | 225 | 3,784,386 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236N | W236N | 1 | 1 | 0 | 0 | 236 | W | N | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,041 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.807352 | 0.051867 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182764,"numValue":-0.807351690614734,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182765,"numValue":0.0518673450896483,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12662 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,662 | train | mutant | 3,780,442 | 225 | 3,784,387 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236P | W236P | 1 | 1 | 0 | 0 | 236 | W | P | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,833,663 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.61594 | 0.064494 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9660008,"numValue":0.615939646896887,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9660009,"numValue":0.0644939782824035,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12663 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,663 | train | mutant | 3,780,442 | 225 | 3,784,387 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236P | W236P | 1 | 1 | 0 | 0 | 236 | W | P | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,042 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.983112 | 0.057736 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182766,"numValue":-0.983112099825162,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182767,"numValue":0.057735632029846,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12664 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,664 | train | mutant | 3,780,443 | 225 | 3,784,388 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236Q | W236Q | 1 | 1 | 0 | 0 | 236 | W | Q | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,833,664 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.479924 | 0.057011 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9660010,"numValue":0.479923995485671,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9660011,"numValue":0.0570106269274383,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12665 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,665 | train | mutant | 3,780,443 | 225 | 3,784,388 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236Q | W236Q | 1 | 1 | 0 | 0 | 236 | W | Q | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,043 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.76115 | 0.074566 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182768,"numValue":-0.761150256616261,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182769,"numValue":0.0745662385308268,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12666 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,666 | train | mutant | 3,780,444 | 225 | 3,784,389 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236R | W236R | 1 | 1 | 0 | 0 | 236 | W | R | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,833,665 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.661374 | 0.062546 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9660012,"numValue":0.661374236317893,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9660013,"numValue":0.0625463977114835,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12667 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,667 | train | mutant | 3,780,444 | 225 | 3,784,389 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236R | W236R | 1 | 1 | 0 | 0 | 236 | W | R | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,044 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.847377 | 0.05224 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182770,"numValue":-0.847377375017427,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182771,"numValue":0.0522401259548964,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12668 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,668 | train | mutant | 3,780,445 | 225 | 3,784,390 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236S | W236S | 1 | 1 | 0 | 0 | 236 | W | S | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,833,666 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.501578 | 0.055821 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9660014,"numValue":0.50157766932088,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9660015,"numValue":0.0558214472397538,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12669 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,669 | train | mutant | 3,780,445 | 225 | 3,784,390 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236S | W236S | 1 | 1 | 0 | 0 | 236 | W | S | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,045 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.860513 | 0.046125 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182772,"numValue":-0.860513345190948,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182773,"numValue":0.0461251352638552,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12670 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,670 | train | mutant | 3,780,446 | 225 | 3,784,391 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236T | W236T | 1 | 1 | 0 | 0 | 236 | W | T | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,833,667 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.473153 | 0.069414 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9660016,"numValue":0.473152878125647,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9660017,"numValue":0.0694139820038415,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12671 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,671 | train | mutant | 3,780,446 | 225 | 3,784,391 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236T | W236T | 1 | 1 | 0 | 0 | 236 | W | T | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,046 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.655728 | 0.047167 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182774,"numValue":-0.655728225769205,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182775,"numValue":0.0471670359007428,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12672 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,672 | train | mutant | 3,780,447 | 225 | 3,784,392 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236V | W236V | 1 | 1 | 0 | 0 | 236 | W | V | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,833,668 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.265804 | 0.057439 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9660018,"numValue":0.265803763522213,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9660019,"numValue":0.0574385317651653,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12673 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,673 | train | mutant | 3,780,447 | 225 | 3,784,392 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236V | W236V | 1 | 1 | 0 | 0 | 236 | W | V | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,047 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.289681 | 0.04812 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182776,"numValue":-0.289680570680798,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182777,"numValue":0.0481200101993163,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12674 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,674 | train | mutant | 3,780,448 | 225 | 3,784,393 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236Y | W236Y | 1 | 1 | 0 | 0 | 236 | W | Y | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,833,669 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.079605 | 0.130026 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9660020,"numValue":0.0796049284653816,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9660021,"numValue":0.13002585014912,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12675 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,675 | train | mutant | 3,780,448 | 225 | 3,784,393 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W236Y | W236Y | 1 | 1 | 0 | 0 | 236 | W | Y | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,768 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.187226 | 0.047296 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184218,"numValue":-0.187225907348725,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184219,"numValue":0.0472964628709482,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12676 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,676 | train | mutant | 4,906,043 | 225 | 4,912,631 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delW236 | delW236 | 1 | 0 | 1 | 0 | 236 | W | - | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,029 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.099689 | 0.068521 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182740,"numValue":-1.09968891178196,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182741,"numValue":0.0685206399833465,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16900,"numValue":5.0,"position":236,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12677 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,677 | train | mutant | 3,781,738 | 225 | 3,785,683 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237A | E237A | 1 | 1 | 0 | 0 | 237 | E | A | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,834,960 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.135306 | 0.04107 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9662602,"numValue":0.135305514939364,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9662603,"numValue":0.0410704360698965,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12678 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,678 | train | mutant | 3,781,738 | 225 | 3,785,683 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237A | E237A | 1 | 1 | 0 | 0 | 237 | E | A | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,049 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.225643 | 0.044845 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182780,"numValue":-0.22564342225995,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182781,"numValue":0.0448453869082057,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12679 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,679 | train | mutant | 3,781,739 | 225 | 3,785,684 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237C | E237C | 1 | 1 | 0 | 0 | 237 | E | C | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,834,961 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.194936 | 0.078556 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9662604,"numValue":0.194936380313002,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9662605,"numValue":0.078556234437608,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12680 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,680 | train | mutant | 3,781,739 | 225 | 3,785,684 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237C | E237C | 1 | 1 | 0 | 0 | 237 | E | C | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,050 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.10311 | 0.064158 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182782,"numValue":-0.103110312068389,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182783,"numValue":0.0641581012902741,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12681 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,681 | train | mutant | 3,781,740 | 225 | 3,785,685 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237D | E237D | 1 | 1 | 0 | 0 | 237 | E | D | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,834,962 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.194922 | 0.063407 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9662606,"numValue":0.194921785423266,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9662607,"numValue":0.0634066207375577,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12682 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,682 | train | mutant | 3,781,740 | 225 | 3,785,685 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237D | E237D | 1 | 1 | 0 | 0 | 237 | E | D | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,051 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.250296 | 0.059914 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182784,"numValue":-0.250296292159591,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182785,"numValue":0.0599140090424543,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12683 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,683 | train | mutant | 3,781,741 | 225 | 3,785,686 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237F | E237F | 1 | 1 | 0 | 0 | 237 | E | F | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,834,963 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.441736 | 0.08146 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9662608,"numValue":0.441735999500934,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9662609,"numValue":0.0814595315991932,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12684 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,684 | train | mutant | 3,781,741 | 225 | 3,785,686 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237F | E237F | 1 | 1 | 0 | 0 | 237 | E | F | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,752 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.397139 | 0.065821 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184186,"numValue":-0.39713932976857,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184187,"numValue":0.0658211256650941,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12685 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,685 | train | mutant | 3,781,742 | 225 | 3,785,687 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237G | E237G | 1 | 1 | 0 | 0 | 237 | E | G | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,834,964 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.26784 | 0.055349 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9662610,"numValue":0.267839688749899,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9662611,"numValue":0.0553486763381371,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12686 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,686 | train | mutant | 3,781,742 | 225 | 3,785,687 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237G | E237G | 1 | 1 | 0 | 0 | 237 | E | G | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,753 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.20726 | 0.043493 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184188,"numValue":-0.207259795556232,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184189,"numValue":0.0434933262259101,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12687 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,687 | train | mutant | 3,781,743 | 225 | 3,785,688 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237H | E237H | 1 | 1 | 0 | 0 | 237 | E | H | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,834,965 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.276849 | 0.146261 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9662612,"numValue":0.276849360620161,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9662613,"numValue":0.146261218994403,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12688 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,688 | train | mutant | 3,781,743 | 225 | 3,785,688 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237H | E237H | 1 | 1 | 0 | 0 | 237 | E | H | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,754 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.184028 | 0.065236 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184190,"numValue":-0.184028028378753,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184191,"numValue":0.0652357841160842,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12689 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,689 | train | mutant | 3,781,744 | 225 | 3,785,689 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237I | E237I | 1 | 1 | 0 | 0 | 237 | E | I | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,834,966 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.276836 | 0.065914 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9662614,"numValue":0.276835947275084,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9662615,"numValue":0.0659139631542658,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12690 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,690 | train | mutant | 3,781,744 | 225 | 3,785,689 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237I | E237I | 1 | 1 | 0 | 0 | 237 | E | I | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,755 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.60939 | 0.066782 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184192,"numValue":-0.60939009219197,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184193,"numValue":0.0667824149264036,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12691 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,691 | train | mutant | 3,781,745 | 225 | 3,785,690 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237K | E237K | 1 | 1 | 0 | 0 | 237 | E | K | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,834,967 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.275782 | 0.117369 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9662616,"numValue":0.275781570580143,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9662617,"numValue":0.117369150517575,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12692 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,692 | train | mutant | 3,781,745 | 225 | 3,785,690 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237K | E237K | 1 | 1 | 0 | 0 | 237 | E | K | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,756 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.076471 | 0.054725 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184194,"numValue":-0.076470603704448,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184195,"numValue":0.0547254165968399,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12693 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,693 | train | mutant | 3,781,746 | 225 | 3,785,691 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237L | E237L | 1 | 1 | 0 | 0 | 237 | E | L | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,834,968 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.343815 | 0.106526 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9662618,"numValue":0.343814619451011,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9662619,"numValue":0.10652622096172,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12694 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,694 | train | mutant | 3,781,746 | 225 | 3,785,691 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237L | E237L | 1 | 1 | 0 | 0 | 237 | E | L | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,757 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.338004 | 0.049743 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184196,"numValue":-0.338004428756033,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184197,"numValue":0.0497426612526791,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12695 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,695 | train | mutant | 3,781,747 | 225 | 3,785,692 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237M | E237M | 1 | 1 | 0 | 0 | 237 | E | M | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,834,969 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.236002 | 0.074027 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9662620,"numValue":0.236002067698651,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9662621,"numValue":0.0740270586825092,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12696 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,696 | train | mutant | 3,781,747 | 225 | 3,785,692 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237M | E237M | 1 | 1 | 0 | 0 | 237 | E | M | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,758 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.229395 | 0.059656 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184198,"numValue":-0.22939510161885,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184199,"numValue":0.0596562451976366,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12697 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,697 | train | mutant | 3,781,748 | 225 | 3,785,693 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237N | E237N | 1 | 1 | 0 | 0 | 237 | E | N | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,834,970 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.31412 | 0.078914 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9662622,"numValue":0.314120117860002,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9662623,"numValue":0.0789136978333489,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12698 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,698 | train | mutant | 3,781,748 | 225 | 3,785,693 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237N | E237N | 1 | 1 | 0 | 0 | 237 | E | N | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,759 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.207164 | 0.063271 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184200,"numValue":-0.20716351704034,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184201,"numValue":0.0632709464862008,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12699 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,699 | train | mutant | 3,781,749 | 225 | 3,785,694 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237P | E237P | 1 | 1 | 0 | 0 | 237 | E | P | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,834,971 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 1.06963 | 0.097263 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9662624,"numValue":1.06963049274821,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9662625,"numValue":0.0972634509727733,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12700 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,700 | train | mutant | 3,781,749 | 225 | 3,785,694 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237P | E237P | 1 | 1 | 0 | 0 | 237 | E | P | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,760 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.273508 | 0.094551 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184202,"numValue":-1.27350834611202,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184203,"numValue":0.0945510724366413,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12701 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,701 | train | mutant | 3,781,750 | 225 | 3,785,695 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237Q | E237Q | 1 | 1 | 0 | 0 | 237 | E | Q | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,834,972 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.009132 | 0.057053 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9662626,"numValue":-0.00913243886141613,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9662627,"numValue":0.0570530331278768,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12702 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,702 | train | mutant | 3,781,750 | 225 | 3,785,695 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237Q | E237Q | 1 | 1 | 0 | 0 | 237 | E | Q | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,761 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.085399 | 0.058904 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184204,"numValue":-0.0853990435954808,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184205,"numValue":0.058903999669343,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12704 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,704 | train | mutant | 3,781,751 | 225 | 3,785,696 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237R | E237R | 1 | 1 | 0 | 0 | 237 | E | R | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,762 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.228291 | 0.044913 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184206,"numValue":-0.228290683601851,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184207,"numValue":0.0449127182141125,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12705 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,705 | train | mutant | 3,781,752 | 225 | 3,785,697 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237S | E237S | 1 | 1 | 0 | 0 | 237 | E | S | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,834,974 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.073825 | 0.06186 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9662630,"numValue":0.0738249582818524,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9662631,"numValue":0.0618596400699441,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12706 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,706 | train | mutant | 3,781,752 | 225 | 3,785,697 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237S | E237S | 1 | 1 | 0 | 0 | 237 | E | S | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,763 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.134949 | 0.047418 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184208,"numValue":-0.134949060290454,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184209,"numValue":0.0474180045511332,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12707 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,707 | train | mutant | 3,781,753 | 225 | 3,785,698 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237T | E237T | 1 | 1 | 0 | 0 | 237 | E | T | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,834,975 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.106267 | 0.074971 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9662632,"numValue":0.106266956305198,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9662633,"numValue":0.0749712760304444,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12708 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,708 | train | mutant | 3,781,753 | 225 | 3,785,698 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237T | E237T | 1 | 1 | 0 | 0 | 237 | E | T | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,764 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.25648 | 0.056567 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184210,"numValue":-0.256479600812405,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184211,"numValue":0.0565666198812756,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12709 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,709 | train | mutant | 3,781,754 | 225 | 3,785,699 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237V | E237V | 1 | 1 | 0 | 0 | 237 | E | V | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,834,976 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.139205 | 0.098293 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9662634,"numValue":0.139204719214498,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9662635,"numValue":0.0982927451625328,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12711 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,711 | train | mutant | 3,781,755 | 225 | 3,785,700 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237W | E237W | 1 | 1 | 0 | 0 | 237 | E | W | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,834,977 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.727523 | 0.034952 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9662636,"numValue":0.72752268769983,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9662637,"numValue":0.0349523989527985,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12713 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,713 | train | mutant | 3,781,756 | 225 | 3,785,701 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237Y | E237Y | 1 | 1 | 0 | 0 | 237 | E | Y | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,834,978 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.441528 | 0.142788 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9662638,"numValue":0.441528452742041,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9662639,"numValue":0.142787770270998,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12714 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,714 | train | mutant | 3,781,756 | 225 | 3,785,701 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E237Y | E237Y | 1 | 1 | 0 | 0 | 237 | E | Y | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,767 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.29253 | 0.058912 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184216,"numValue":-0.292529937337048,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184217,"numValue":0.0589117496920271,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12715 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,715 | train | mutant | 4,906,044 | 225 | 4,912,632 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delE237 | delE237 | 1 | 0 | 1 | 0 | 237 | E | - | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,048 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.09503 | 0.062033 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182778,"numValue":-1.09503038428619,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182779,"numValue":0.0620332185307514,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16901,"numValue":7.0,"position":237,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12716 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,716 | train | mutant | 3,783,048 | 225 | 3,786,993 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238A | Q238A | 1 | 1 | 0 | 0 | 238 | Q | A | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,836,271 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.08065 | 0.069905 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9665224,"numValue":-0.0806499765839229,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9665225,"numValue":0.069905163621801,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12717 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,717 | train | mutant | 3,783,048 | 225 | 3,786,993 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238A | Q238A | 1 | 1 | 0 | 0 | 238 | Q | A | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,053 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.086404 | 0.047075 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182788,"numValue":-0.0864040003357336,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182789,"numValue":0.0470749586291814,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12718 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,718 | train | mutant | 3,783,049 | 225 | 3,786,994 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238C | Q238C | 1 | 1 | 0 | 0 | 238 | Q | C | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,836,272 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.047648 | 0.098925 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9665226,"numValue":0.047648413638899,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9665227,"numValue":0.0989253554255688,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12719 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,719 | train | mutant | 3,783,049 | 225 | 3,786,994 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238C | Q238C | 1 | 1 | 0 | 0 | 238 | Q | C | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,054 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.145738 | 0.052498 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182790,"numValue":-0.145737823901765,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182791,"numValue":0.0524977386185735,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12720 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,720 | train | mutant | 3,783,050 | 225 | 3,786,995 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238D | Q238D | 1 | 1 | 0 | 0 | 238 | Q | D | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,836,273 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.322671 | 0.055462 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9665228,"numValue":0.322671260380267,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9665229,"numValue":0.0554615543631387,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12721 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,721 | train | mutant | 3,783,050 | 225 | 3,786,995 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238D | Q238D | 1 | 1 | 0 | 0 | 238 | Q | D | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,055 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.220222 | 0.061379 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182792,"numValue":-0.220221589141913,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182793,"numValue":0.0613792487007861,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12722 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,722 | train | mutant | 3,783,051 | 225 | 3,786,996 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238E | Q238E | 1 | 1 | 0 | 0 | 238 | Q | E | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,836,274 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.251414 | 0.11856 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9665230,"numValue":-0.251414361281928,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9665231,"numValue":0.118560152034595,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12723 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,723 | train | mutant | 3,783,051 | 225 | 3,786,996 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238E | Q238E | 1 | 1 | 0 | 0 | 238 | Q | E | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,056 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.038844 | 0.060715 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182794,"numValue":0.0388440048659161,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182795,"numValue":0.0607146404926599,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12724 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,724 | train | mutant | 3,783,052 | 225 | 3,786,997 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238F | Q238F | 1 | 1 | 0 | 0 | 238 | Q | F | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,836,275 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.229034 | 0.093111 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9665232,"numValue":0.229034161262531,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9665233,"numValue":0.0931107423526486,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12725 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,725 | train | mutant | 3,783,052 | 225 | 3,786,997 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238F | Q238F | 1 | 1 | 0 | 0 | 238 | Q | F | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,057 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.394794 | 0.062722 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182796,"numValue":-0.39479443070798,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182797,"numValue":0.062721641746982,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12726 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,726 | train | mutant | 3,783,053 | 225 | 3,786,998 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238G | Q238G | 1 | 1 | 0 | 0 | 238 | Q | G | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,836,276 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.260909 | 0.058156 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9665234,"numValue":0.260909456709179,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9665235,"numValue":0.0581561322234174,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12727 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,727 | train | mutant | 3,783,053 | 225 | 3,786,998 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238G | Q238G | 1 | 1 | 0 | 0 | 238 | Q | G | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,058 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.258672 | 0.044023 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182798,"numValue":-0.25867172735191,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182799,"numValue":0.0440233275205378,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] |
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