row_id string | dataset_id string | source_dataset string | source_file string | source_table string | source_sha string | row_index int64 | split string | subject_type string | entry_id int64 | sequence_id int64 | target_sequence_id int64 | source_sequence_length int64 | target_sequence_length int64 | protein_id int64 | protein_name string | organism string | isoform int64 | protein_ids string | protein_names string | organisms string | isoforms string | uniprot_accessions string | interpro_accessions string | ec_numbers string | megascale_ids string | other_references string | mutations string | substitutions string | deletions string | insertions string | mutation_count int64 | substitution_count int64 | deletion_count int64 | insertion_count int64 | first_position int64 | first_source_aa string | first_target_aa string | conservation float64 | feature_types string | pdb_ids string | afdb_ids string | structure_ids string | structure_methods string | structure_resolution_min float64 | residue_positions string | residue_chain_names string | residue_secondary_structures string | residue_in_pocket_any bool | residue_in_tunnel_any bool | residue_asa_mean float64 | residue_bfactor_mean float64 | experiment_id int64 | experiment_dataset string | ph float64 | measure string | method string | buffer string | buffer_conc string | exp_temperature float64 | ion string | ion_conc string | pdb_chain_mutation string | tm float64 | dtm float64 | dg float64 | dg_text string | ddg float64 | dh float64 | dcp float64 | dhvh float64 | cm float64 | m_value float64 | trypsin_ml float64 | chymotrypsin_ml float64 | stabilizing float64 | stabilizing_text string | domainome_fitness float64 | domainome_fitness_std float64 | domainome_ddg float64 | domainome_ddg_std float64 | reversibility string | state string | measurement_types string | measurement_datasets string | annotation_types string | publication_id string | publication_type string | publication_title string | publication_year int64 | publication_doi string | publication_pmid string | publication_journal string | publication_url string | publication_author_count int64 | publication_authors string | annotations_json string | measurements_json string | features_json string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fireprotdb:12728 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,728 | train | mutant | 3,783,054 | 225 | 3,786,999 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238H | Q238H | 1 | 1 | 0 | 0 | 238 | Q | H | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,836,277 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.272483 | 0.06054 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9665236,"numValue":0.272482844179734,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9665237,"numValue":0.0605398771918686,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12729 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,729 | train | mutant | 3,783,054 | 225 | 3,786,999 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238H | Q238H | 1 | 1 | 0 | 0 | 238 | Q | H | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,059 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.312462 | 0.070346 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182800,"numValue":-0.312461977197166,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182801,"numValue":0.0703462238688819,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12730 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,730 | train | mutant | 3,783,055 | 225 | 3,787,000 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238I | Q238I | 1 | 1 | 0 | 0 | 238 | Q | I | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,836,278 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.117878 | 0.124395 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9665238,"numValue":-0.117877568058902,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9665239,"numValue":0.124394529536453,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12731 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,731 | train | mutant | 3,783,055 | 225 | 3,787,000 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238I | Q238I | 1 | 1 | 0 | 0 | 238 | Q | I | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,060 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.225129 | 0.076312 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182802,"numValue":-0.225129406381721,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182803,"numValue":0.0763117282394232,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12732 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,732 | train | mutant | 3,783,056 | 225 | 3,787,001 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238K | Q238K | 1 | 1 | 0 | 0 | 238 | Q | K | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,836,279 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.023478 | 0.082231 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9665240,"numValue":-0.0234776108213665,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9665241,"numValue":0.0822305457529797,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12733 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,733 | train | mutant | 3,783,056 | 225 | 3,787,001 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238K | Q238K | 1 | 1 | 0 | 0 | 238 | Q | K | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,061 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.091907 | 0.059431 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182804,"numValue":-0.0919069938555966,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182805,"numValue":0.0594305476684421,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12734 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,734 | train | mutant | 3,783,057 | 225 | 3,787,002 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238L | Q238L | 1 | 1 | 0 | 0 | 238 | Q | L | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,836,280 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.026647 | 0.107399 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9665242,"numValue":-0.0266470165962486,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9665243,"numValue":0.107398515998363,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12735 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,735 | train | mutant | 3,783,057 | 225 | 3,787,002 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238L | Q238L | 1 | 1 | 0 | 0 | 238 | Q | L | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,062 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.102198 | 0.047519 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182806,"numValue":-0.102197655392958,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182807,"numValue":0.0475192561308617,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12736 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,736 | train | mutant | 3,783,058 | 225 | 3,787,003 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238M | Q238M | 1 | 1 | 0 | 0 | 238 | Q | M | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,836,281 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.047339 | 0.083217 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9665244,"numValue":-0.0473389895984168,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9665245,"numValue":0.0832172930822223,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12737 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,737 | train | mutant | 3,783,058 | 225 | 3,787,003 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238M | Q238M | 1 | 1 | 0 | 0 | 238 | Q | M | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,063 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.145972 | 0.057079 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182808,"numValue":-0.145971756824674,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182809,"numValue":0.0570788852410338,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12738 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,738 | train | mutant | 3,783,059 | 225 | 3,787,004 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238N | Q238N | 1 | 1 | 0 | 0 | 238 | Q | N | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,836,282 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.388218 | 0.183813 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9665246,"numValue":0.38821815924448,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9665247,"numValue":0.18381293630126,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12739 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,739 | train | mutant | 3,783,059 | 225 | 3,787,004 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238N | Q238N | 1 | 1 | 0 | 0 | 238 | Q | N | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,064 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.232062 | 0.062862 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182810,"numValue":-0.2320622552161,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182811,"numValue":0.0628622799923023,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12740 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,740 | train | mutant | 3,783,060 | 225 | 3,787,005 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238P | Q238P | 1 | 1 | 0 | 0 | 238 | Q | P | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,836,283 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.257529 | 0.068987 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9665248,"numValue":0.257529473794675,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9665249,"numValue":0.0689874848921792,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12741 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,741 | train | mutant | 3,783,060 | 225 | 3,787,005 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238P | Q238P | 1 | 1 | 0 | 0 | 238 | Q | P | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,065 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.130846 | 0.059619 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182812,"numValue":-0.13084648154719,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182813,"numValue":0.059619380870023,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12742 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,742 | train | mutant | 3,783,061 | 225 | 3,787,006 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238R | Q238R | 1 | 1 | 0 | 0 | 238 | Q | R | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,836,284 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.027399 | 0.092287 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9665250,"numValue":0.0273989786237348,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9665251,"numValue":0.0922874150277811,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12743 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,743 | train | mutant | 3,783,061 | 225 | 3,787,006 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238R | Q238R | 1 | 1 | 0 | 0 | 238 | Q | R | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,746 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.080251 | 0.043647 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184174,"numValue":-0.0802509279110515,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184175,"numValue":0.0436467114284584,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12744 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,744 | train | mutant | 3,783,062 | 225 | 3,787,007 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238S | Q238S | 1 | 1 | 0 | 0 | 238 | Q | S | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,836,285 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.008731 | 0.067434 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9665252,"numValue":-0.00873109177177319,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9665253,"numValue":0.0674341700199148,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12745 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,745 | train | mutant | 3,783,062 | 225 | 3,787,007 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238S | Q238S | 1 | 1 | 0 | 0 | 238 | Q | S | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,747 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.072126 | 0.046835 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184176,"numValue":-0.0721261351361351,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184177,"numValue":0.0468349148054289,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12746 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,746 | train | mutant | 3,783,063 | 225 | 3,787,008 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238T | Q238T | 1 | 1 | 0 | 0 | 238 | Q | T | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,836,286 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.069094 | 0.086831 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9665254,"numValue":0.069093940940641,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9665255,"numValue":0.0868311475706135,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12747 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,747 | train | mutant | 3,783,063 | 225 | 3,787,008 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238T | Q238T | 1 | 1 | 0 | 0 | 238 | Q | T | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,748 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.014777 | 0.055727 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184178,"numValue":0.0147767629637619,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184179,"numValue":0.0557273894987901,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12748 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,748 | train | mutant | 3,783,064 | 225 | 3,787,009 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238V | Q238V | 1 | 1 | 0 | 0 | 238 | Q | V | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,836,287 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.072117 | 0.101322 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9665256,"numValue":-0.0721170748626268,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9665257,"numValue":0.101322259425675,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12749 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,749 | train | mutant | 3,783,064 | 225 | 3,787,009 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238V | Q238V | 1 | 1 | 0 | 0 | 238 | Q | V | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,749 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.101234 | 0.044912 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184180,"numValue":-0.101234074543832,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184181,"numValue":0.0449118588686814,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12751 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,751 | train | mutant | 3,783,065 | 225 | 3,787,010 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238W | Q238W | 1 | 1 | 0 | 0 | 238 | Q | W | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,750 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.29454 | 0.051427 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184182,"numValue":-0.294539850817554,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184183,"numValue":0.0514265884094202,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12753 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,753 | train | mutant | 3,783,066 | 225 | 3,787,011 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q238Y | Q238Y | 1 | 1 | 0 | 0 | 238 | Q | Y | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,751 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.210162 | 0.059417 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184184,"numValue":-0.210161677766605,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184185,"numValue":0.0594174903920307,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12754 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,754 | train | mutant | 4,906,045 | 225 | 4,912,633 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delQ238 | delQ238 | 1 | 0 | 1 | 0 | 238 | Q | - | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,052 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.335164 | 0.133589 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182786,"numValue":-1.33516364361874,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182787,"numValue":0.133588987007704,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16902,"numValue":7.0,"position":238,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12755 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,755 | train | mutant | 3,784,358 | 225 | 3,788,303 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239C | A239C | 1 | 1 | 0 | 0 | 239 | A | C | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,837,582 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.019351 | 0.073171 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9667846,"numValue":0.019350608111891,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9667847,"numValue":0.0731706075970976,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12756 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,756 | train | mutant | 3,784,358 | 225 | 3,788,303 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239C | A239C | 1 | 1 | 0 | 0 | 239 | A | C | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,727 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.072113 | 0.051916 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184136,"numValue":-0.0721134040927113,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184137,"numValue":0.0519164869172635,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12757 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,757 | train | mutant | 3,784,359 | 225 | 3,788,304 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239D | A239D | 1 | 1 | 0 | 0 | 239 | A | D | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,837,583 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.136403 | 0.0798 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9667848,"numValue":0.136402945996385,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9667849,"numValue":0.0798002051643147,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12758 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,758 | train | mutant | 3,784,359 | 225 | 3,788,304 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239D | A239D | 1 | 1 | 0 | 0 | 239 | A | D | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,728 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.11771 | 0.058878 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184138,"numValue":-0.117710431804648,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184139,"numValue":0.0588777100646732,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12759 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,759 | train | mutant | 3,784,360 | 225 | 3,788,305 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239E | A239E | 1 | 1 | 0 | 0 | 239 | A | E | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,837,584 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.188035 | 0.048002 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9667850,"numValue":0.188035022973178,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9667851,"numValue":0.04800191267099,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12760 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,760 | train | mutant | 3,784,360 | 225 | 3,788,305 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239E | A239E | 1 | 1 | 0 | 0 | 239 | A | E | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,729 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.103522 | 0.068667 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184140,"numValue":-0.103521683909015,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184141,"numValue":0.0686667764480455,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12761 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,761 | train | mutant | 3,784,361 | 225 | 3,788,306 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239F | A239F | 1 | 1 | 0 | 0 | 239 | A | F | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,837,585 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.169317 | 0.054354 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9667852,"numValue":0.169317003743991,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9667853,"numValue":0.0543544098837431,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12762 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,762 | train | mutant | 3,784,361 | 225 | 3,788,306 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239F | A239F | 1 | 1 | 0 | 0 | 239 | A | F | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,730 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.430055 | 0.062798 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184142,"numValue":-0.430054805988188,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184143,"numValue":0.0627978131711659,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12763 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,763 | train | mutant | 3,784,362 | 225 | 3,788,307 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239G | A239G | 1 | 1 | 0 | 0 | 239 | A | G | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,837,586 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.105001 | 0.084163 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9667854,"numValue":0.105001263161263,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9667855,"numValue":0.0841626525899942,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12764 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,764 | train | mutant | 3,784,362 | 225 | 3,788,307 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239G | A239G | 1 | 1 | 0 | 0 | 239 | A | G | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,731 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.046999 | 0.049443 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184144,"numValue":-0.0469990338689636,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184145,"numValue":0.0494432509820618,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12765 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,765 | train | mutant | 3,784,363 | 225 | 3,788,308 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239H | A239H | 1 | 1 | 0 | 0 | 239 | A | H | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,837,587 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.128322 | 0.049785 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9667856,"numValue":0.128321533869483,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9667857,"numValue":0.0497845867418262,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12766 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,766 | train | mutant | 3,784,363 | 225 | 3,788,308 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239H | A239H | 1 | 1 | 0 | 0 | 239 | A | H | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,732 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.123424 | 0.069103 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184146,"numValue":-0.123424283231215,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184147,"numValue":0.0691026316765555,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12767 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,767 | train | mutant | 3,784,364 | 225 | 3,788,309 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239I | A239I | 1 | 1 | 0 | 0 | 239 | A | I | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,837,588 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.174389 | 0.145086 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9667858,"numValue":0.174389239929808,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9667859,"numValue":0.145086212216219,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12768 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,768 | train | mutant | 3,784,364 | 225 | 3,788,309 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239I | A239I | 1 | 1 | 0 | 0 | 239 | A | I | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,733 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.361911 | 0.066817 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184148,"numValue":-0.361910941234964,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184149,"numValue":0.0668165022951704,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12769 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,769 | train | mutant | 3,784,365 | 225 | 3,788,310 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239K | A239K | 1 | 1 | 0 | 0 | 239 | A | K | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,837,589 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.079315 | 0.058773 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9667860,"numValue":-0.0793149053881941,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9667861,"numValue":0.0587729638014979,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12770 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,770 | train | mutant | 3,784,365 | 225 | 3,788,310 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239K | A239K | 1 | 1 | 0 | 0 | 239 | A | K | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,734 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.0545 | 0.06347 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184150,"numValue":-0.0545000055161225,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184151,"numValue":0.0634695507636094,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12771 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,771 | train | mutant | 3,784,366 | 225 | 3,788,311 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239L | A239L | 1 | 1 | 0 | 0 | 239 | A | L | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,837,590 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.113004 | 0.063173 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9667862,"numValue":0.113003613071293,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9667863,"numValue":0.0631726951502005,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12772 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,772 | train | mutant | 3,784,366 | 225 | 3,788,311 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239L | A239L | 1 | 1 | 0 | 0 | 239 | A | L | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,735 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.144161 | 0.046309 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184152,"numValue":-0.144160765897663,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184153,"numValue":0.0463089954015988,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12773 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,773 | train | mutant | 3,784,367 | 225 | 3,788,312 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239M | A239M | 1 | 1 | 0 | 0 | 239 | A | M | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,837,591 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.000624 | 0.074866 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9667864,"numValue":0.000623834649536199,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9667865,"numValue":0.0748660341597794,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12774 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,774 | train | mutant | 3,784,367 | 225 | 3,788,312 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239M | A239M | 1 | 1 | 0 | 0 | 239 | A | M | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,736 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.007259 | 0.062598 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184154,"numValue":-0.00725908182210978,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184155,"numValue":0.0625976175133294,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12775 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,775 | train | mutant | 3,784,368 | 225 | 3,788,313 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239N | A239N | 1 | 1 | 0 | 0 | 239 | A | N | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,837,592 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.110455 | 0.08865 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9667866,"numValue":0.110454828819644,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9667867,"numValue":0.0886501479506591,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12776 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,776 | train | mutant | 3,784,368 | 225 | 3,788,313 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239N | A239N | 1 | 1 | 0 | 0 | 239 | A | N | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,737 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.07543 | 0.084734 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184156,"numValue":0.0754298409045665,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184157,"numValue":0.0847340852836606,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12778 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,778 | train | mutant | 3,784,369 | 225 | 3,788,314 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239P | A239P | 1 | 1 | 0 | 0 | 239 | A | P | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,738 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.060315 | 0.075552 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184158,"numValue":-1.06031481809549,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184159,"numValue":0.0755519156971947,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12779 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,779 | train | mutant | 3,784,370 | 225 | 3,788,315 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239Q | A239Q | 1 | 1 | 0 | 0 | 239 | A | Q | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,837,594 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.003637 | 0.120324 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9667870,"numValue":0.0036374883072934,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9667871,"numValue":0.120324085681865,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12780 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,780 | train | mutant | 3,784,370 | 225 | 3,788,315 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239Q | A239Q | 1 | 1 | 0 | 0 | 239 | A | Q | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,739 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.039878 | 0.060907 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184160,"numValue":-0.0398784021440858,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184161,"numValue":0.0609066644119989,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12781 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,781 | train | mutant | 3,784,371 | 225 | 3,788,316 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239R | A239R | 1 | 1 | 0 | 0 | 239 | A | R | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,837,595 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.084643 | 0.079824 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9667872,"numValue":-0.0846428773504859,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9667873,"numValue":0.0798235029744216,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12782 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,782 | train | mutant | 3,784,371 | 225 | 3,788,316 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239R | A239R | 1 | 1 | 0 | 0 | 239 | A | R | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,740 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.041319 | 0.047299 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184162,"numValue":-0.0413193971215978,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184163,"numValue":0.0472991284331651,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12783 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,783 | train | mutant | 3,784,372 | 225 | 3,788,317 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239S | A239S | 1 | 1 | 0 | 0 | 239 | A | S | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,837,596 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.031778 | 0.088828 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9667874,"numValue":0.031778179227393,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9667875,"numValue":0.0888282067307144,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12785 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,785 | train | mutant | 3,784,373 | 225 | 3,788,318 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239T | A239T | 1 | 1 | 0 | 0 | 239 | A | T | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,837,597 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.119933 | 0.068343 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9667876,"numValue":0.119933185697565,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9667877,"numValue":0.0683429320258461,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12787 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,787 | train | mutant | 3,784,374 | 225 | 3,788,319 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239V | A239V | 1 | 1 | 0 | 0 | 239 | A | V | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,837,598 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.065208 | 0.090463 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9667878,"numValue":0.0652081331313749,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9667879,"numValue":0.0904625811929639,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12788 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,788 | train | mutant | 3,784,374 | 225 | 3,788,319 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239V | A239V | 1 | 1 | 0 | 0 | 239 | A | V | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,743 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.189901 | 0.047693 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184168,"numValue":-0.189901017848115,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184169,"numValue":0.047692963261475,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12789 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,789 | train | mutant | 3,784,375 | 225 | 3,788,320 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239W | A239W | 1 | 1 | 0 | 0 | 239 | A | W | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,837,599 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.373604 | 0.063882 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9667880,"numValue":0.373604421058342,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9667881,"numValue":0.0638820934379604,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12790 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,790 | train | mutant | 3,784,375 | 225 | 3,788,320 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239W | A239W | 1 | 1 | 0 | 0 | 239 | A | W | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,744 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.476941 | 0.062638 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184170,"numValue":-0.476940931415788,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184171,"numValue":0.0626380624469058,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12792 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,792 | train | mutant | 3,784,376 | 225 | 3,788,321 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A239Y | A239Y | 1 | 1 | 0 | 0 | 239 | A | Y | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,745 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.382283 | 0.066539 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184172,"numValue":-0.38228299778341,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184173,"numValue":0.0665393713505445,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12793 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,793 | train | mutant | 4,906,046 | 225 | 4,912,634 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delA239 | delA239 | 1 | 0 | 1 | 0 | 239 | A | - | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,066 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.243795 | 0.104091 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182814,"numValue":-1.24379523655518,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182815,"numValue":0.104090522842987,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16903,"numValue":7.0,"position":239,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12794 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,794 | train | mutant | 3,785,667 | 225 | 3,789,612 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240A | M240A | 1 | 1 | 0 | 0 | 240 | M | A | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,838,893 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.054998 | 0.075597 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9670468,"numValue":-0.0549978475969746,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9670469,"numValue":0.0755966676182565,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12795 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,795 | train | mutant | 3,785,667 | 225 | 3,789,612 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240A | M240A | 1 | 1 | 0 | 0 | 240 | M | A | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,068 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.107709 | 0.046402 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182818,"numValue":-0.107708605814961,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182819,"numValue":0.0464018524495699,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12798 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,798 | train | mutant | 3,785,669 | 225 | 3,789,614 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240D | M240D | 1 | 1 | 0 | 0 | 240 | M | D | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,838,895 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.181482 | 0.058205 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9670472,"numValue":0.181481714931367,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9670473,"numValue":0.0582046622010295,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12799 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,799 | train | mutant | 3,785,669 | 225 | 3,789,614 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240D | M240D | 1 | 1 | 0 | 0 | 240 | M | D | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,070 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.41362 | 0.056274 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182822,"numValue":-0.41362046117067,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182823,"numValue":0.0562744026501927,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12800 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,800 | train | mutant | 3,785,670 | 225 | 3,789,615 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240E | M240E | 1 | 1 | 0 | 0 | 240 | M | E | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,838,896 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.068973 | 0.100911 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9670474,"numValue":-0.0689731195596916,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9670475,"numValue":0.100910749926687,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12801 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,801 | train | mutant | 3,785,670 | 225 | 3,789,615 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240E | M240E | 1 | 1 | 0 | 0 | 240 | M | E | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,071 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.040814 | 0.057282 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182824,"numValue":-0.0408141338357226,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182825,"numValue":0.0572818021594022,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12802 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,802 | train | mutant | 3,785,671 | 225 | 3,789,616 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240F | M240F | 1 | 1 | 0 | 0 | 240 | M | F | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,838,897 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.024102 | 0.076189 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9670476,"numValue":0.0241019491465114,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9670477,"numValue":0.0761886777562607,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12803 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,803 | train | mutant | 3,785,671 | 225 | 3,789,616 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240F | M240F | 1 | 1 | 0 | 0 | 240 | M | F | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,072 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.069324 | 0.0618 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182826,"numValue":-0.0693237142025088,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182827,"numValue":0.0617995720563193,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12804 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,804 | train | mutant | 3,785,672 | 225 | 3,789,617 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240G | M240G | 1 | 1 | 0 | 0 | 240 | M | G | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,838,898 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.328569 | 0.058438 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9670478,"numValue":0.328569497557721,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9670479,"numValue":0.0584375108948264,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12805 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,805 | train | mutant | 3,785,672 | 225 | 3,789,617 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240G | M240G | 1 | 1 | 0 | 0 | 240 | M | G | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,073 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.384531 | 0.048098 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182828,"numValue":-0.384530822637894,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182829,"numValue":0.0480980809770191,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12806 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,806 | train | mutant | 3,785,673 | 225 | 3,789,618 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240H | M240H | 1 | 1 | 0 | 0 | 240 | M | H | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,838,899 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.00563 | 0.114467 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9670480,"numValue":-0.00562984041853039,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9670481,"numValue":0.114466504893473,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12807 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,807 | train | mutant | 3,785,673 | 225 | 3,789,618 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240H | M240H | 1 | 1 | 0 | 0 | 240 | M | H | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,074 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.019581 | 0.06828 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182830,"numValue":-0.0195811404757534,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182831,"numValue":0.0682795060640009,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12808 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,808 | train | mutant | 3,785,674 | 225 | 3,789,619 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240I | M240I | 1 | 1 | 0 | 0 | 240 | M | I | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,838,900 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.031206 | 0.081876 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9670482,"numValue":-0.0312058164891408,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9670483,"numValue":0.0818762511474852,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12809 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,809 | train | mutant | 3,785,674 | 225 | 3,789,619 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240I | M240I | 1 | 1 | 0 | 0 | 240 | M | I | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,075 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.105818 | 0.070324 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182832,"numValue":-0.105818045866552,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182833,"numValue":0.0703236660513157,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12810 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,810 | train | mutant | 3,785,675 | 225 | 3,789,620 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240K | M240K | 1 | 1 | 0 | 0 | 240 | M | K | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,838,901 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.125105 | 0.069352 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9670484,"numValue":-0.125105290539052,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9670485,"numValue":0.0693520049227336,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12811 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,811 | train | mutant | 3,785,675 | 225 | 3,789,620 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240K | M240K | 1 | 1 | 0 | 0 | 240 | M | K | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,076 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.037903 | 0.061708 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182834,"numValue":0.0379027033427818,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182835,"numValue":0.0617082825180697,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12812 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,812 | train | mutant | 3,785,676 | 225 | 3,789,621 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240L | M240L | 1 | 1 | 0 | 0 | 240 | M | L | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,838,902 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.08538 | 0.118776 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9670486,"numValue":-0.0853797943759856,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9670487,"numValue":0.118776436597559,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12814 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,814 | train | mutant | 3,785,677 | 225 | 3,789,622 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240N | M240N | 1 | 1 | 0 | 0 | 240 | M | N | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,838,903 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.035675 | 0.054897 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9670488,"numValue":-0.0356745804284842,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9670489,"numValue":0.0548974680639,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12815 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,815 | train | mutant | 3,785,677 | 225 | 3,789,622 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240N | M240N | 1 | 1 | 0 | 0 | 240 | M | N | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,718 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.007745 | 0.068027 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184118,"numValue":-0.00774524854284941,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184119,"numValue":0.0680273597920938,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12816 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,816 | train | mutant | 3,785,678 | 225 | 3,789,623 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240P | M240P | 1 | 1 | 0 | 0 | 240 | M | P | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,838,904 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.383696 | 0.04699 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9670490,"numValue":0.383696106515751,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9670491,"numValue":0.0469899748096254,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12817 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,817 | train | mutant | 3,785,678 | 225 | 3,789,623 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240P | M240P | 1 | 1 | 0 | 0 | 240 | M | P | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,719 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.375985 | 0.057833 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184120,"numValue":-0.375985109739784,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184121,"numValue":0.0578325630117126,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12818 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,818 | train | mutant | 3,785,679 | 225 | 3,789,624 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240Q | M240Q | 1 | 1 | 0 | 0 | 240 | M | Q | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,838,905 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.100755 | 0.098458 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9670492,"numValue":-0.100755241770402,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9670493,"numValue":0.0984576269064428,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12819 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,819 | train | mutant | 3,785,679 | 225 | 3,789,624 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240Q | M240Q | 1 | 1 | 0 | 0 | 240 | M | Q | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,720 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.064114 | 0.057987 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184122,"numValue":0.0641143303716033,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184123,"numValue":0.0579867041199642,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12820 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,820 | train | mutant | 3,785,680 | 225 | 3,789,625 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240R | M240R | 1 | 1 | 0 | 0 | 240 | M | R | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,838,906 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.116 | 0.091773 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9670494,"numValue":-0.115999643484091,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9670495,"numValue":0.0917732292979585,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12821 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,821 | train | mutant | 3,785,680 | 225 | 3,789,625 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240R | M240R | 1 | 1 | 0 | 0 | 240 | M | R | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,721 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.040772 | 0.045866 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184124,"numValue":0.0407719622543818,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184125,"numValue":0.0458664722890957,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12822 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,822 | train | mutant | 3,785,681 | 225 | 3,789,626 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240S | M240S | 1 | 1 | 0 | 0 | 240 | M | S | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,838,907 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.070533 | 0.105901 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9670496,"numValue":-0.070532871037144,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9670497,"numValue":0.105901105067661,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12823 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,823 | train | mutant | 3,785,681 | 225 | 3,789,626 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240S | M240S | 1 | 1 | 0 | 0 | 240 | M | S | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,722 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.054921 | 0.048952 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184126,"numValue":0.0549209256393161,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184127,"numValue":0.0489524374304723,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12824 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,824 | train | mutant | 3,785,682 | 225 | 3,789,627 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240T | M240T | 1 | 1 | 0 | 0 | 240 | M | T | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,838,908 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.093772 | 0.059956 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9670498,"numValue":-0.0937720877817824,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9670499,"numValue":0.0599557282643264,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12825 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,825 | train | mutant | 3,785,682 | 225 | 3,789,627 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240T | M240T | 1 | 1 | 0 | 0 | 240 | M | T | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,723 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.094348 | 0.055139 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184128,"numValue":0.0943481714320774,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184129,"numValue":0.0551385866973494,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12826 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,826 | train | mutant | 3,785,683 | 225 | 3,789,628 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240V | M240V | 1 | 1 | 0 | 0 | 240 | M | V | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,838,909 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.121236 | 0.069428 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9670500,"numValue":-0.121235613627578,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9670501,"numValue":0.0694276091522377,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12827 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,827 | train | mutant | 3,785,683 | 225 | 3,789,628 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240V | M240V | 1 | 1 | 0 | 0 | 240 | M | V | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,724 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.060757 | 0.045879 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184130,"numValue":-0.0607565176686214,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184131,"numValue":0.0458793704274642,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12828 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,828 | train | mutant | 3,785,684 | 225 | 3,789,629 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240W | M240W | 1 | 1 | 0 | 0 | 240 | M | W | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,838,910 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.078579 | 0.073428 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9670502,"numValue":-0.0785794602297548,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9670503,"numValue":0.073427745473234,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12830 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,830 | train | mutant | 3,785,685 | 225 | 3,789,630 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240Y | M240Y | 1 | 1 | 0 | 0 | 240 | M | Y | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,838,911 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.015424 | 0.13764 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9670504,"numValue":-0.01542388960014,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9670505,"numValue":0.137640331580861,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12831 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,831 | train | mutant | 3,785,685 | 225 | 3,789,630 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M240Y | M240Y | 1 | 1 | 0 | 0 | 240 | M | Y | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,726 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.006031 | 0.060236 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184134,"numValue":0.00603053613172971,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184135,"numValue":0.060235929389225,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12832 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,832 | train | mutant | 4,906,047 | 225 | 4,912,635 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delM240 | delM240 | 1 | 0 | 1 | 0 | 240 | M | - | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,067 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.101746 | 0.080964 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182816,"numValue":-1.10174553227802,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182817,"numValue":0.0809640254808174,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16904,"numValue":3.0,"position":240,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12833 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,833 | train | mutant | 3,786,977 | 225 | 3,790,922 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241A | T241A | 1 | 1 | 0 | 0 | 241 | T | A | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,840,204 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.160977 | 0.061653 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9673090,"numValue":0.160977076397465,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9673091,"numValue":0.0616533041130062,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12834 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,834 | train | mutant | 3,786,977 | 225 | 3,790,922 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241A | T241A | 1 | 1 | 0 | 0 | 241 | T | A | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,079 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.14153 | 0.04932 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182840,"numValue":-0.141530214050256,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182841,"numValue":0.0493201895335681,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12835 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,835 | train | mutant | 3,786,978 | 225 | 3,790,923 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241C | T241C | 1 | 1 | 0 | 0 | 241 | T | C | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,840,205 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.212613 | 0.077278 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9673092,"numValue":0.212613312411456,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9673093,"numValue":0.0772782239719266,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12836 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,836 | train | mutant | 3,786,978 | 225 | 3,790,923 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241C | T241C | 1 | 1 | 0 | 0 | 241 | T | C | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,080 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.381257 | 0.051547 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182842,"numValue":-0.38125655740738,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182843,"numValue":0.0515472548303697,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12837 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,837 | train | mutant | 3,786,979 | 225 | 3,790,924 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241D | T241D | 1 | 1 | 0 | 0 | 241 | T | D | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,840,206 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.146347 | 0.128946 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9673094,"numValue":-0.146346706563656,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9673095,"numValue":0.128946447213028,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] |
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