row_id string | dataset_id string | source_dataset string | source_file string | source_table string | source_sha string | row_index int64 | split string | subject_type string | entry_id int64 | sequence_id int64 | target_sequence_id int64 | source_sequence_length int64 | target_sequence_length int64 | protein_id int64 | protein_name string | organism string | isoform int64 | protein_ids string | protein_names string | organisms string | isoforms string | uniprot_accessions string | interpro_accessions string | ec_numbers string | megascale_ids string | other_references string | mutations string | substitutions string | deletions string | insertions string | mutation_count int64 | substitution_count int64 | deletion_count int64 | insertion_count int64 | first_position int64 | first_source_aa string | first_target_aa string | conservation float64 | feature_types string | pdb_ids string | afdb_ids string | structure_ids string | structure_methods string | structure_resolution_min float64 | residue_positions string | residue_chain_names string | residue_secondary_structures string | residue_in_pocket_any bool | residue_in_tunnel_any bool | residue_asa_mean float64 | residue_bfactor_mean float64 | experiment_id int64 | experiment_dataset string | ph float64 | measure string | method string | buffer string | buffer_conc string | exp_temperature float64 | ion string | ion_conc string | pdb_chain_mutation string | tm float64 | dtm float64 | dg float64 | dg_text string | ddg float64 | dh float64 | dcp float64 | dhvh float64 | cm float64 | m_value float64 | trypsin_ml float64 | chymotrypsin_ml float64 | stabilizing float64 | stabilizing_text string | domainome_fitness float64 | domainome_fitness_std float64 | domainome_ddg float64 | domainome_ddg_std float64 | reversibility string | state string | measurement_types string | measurement_datasets string | annotation_types string | publication_id string | publication_type string | publication_title string | publication_year int64 | publication_doi string | publication_pmid string | publication_journal string | publication_url string | publication_author_count int64 | publication_authors string | annotations_json string | measurements_json string | features_json string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fireprotdb:13606 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,606 | train | mutant | 3,811,937 | 225 | 3,815,882 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260V | D260V | 1 | 1 | 0 | 0 | 260 | D | V | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,865,205 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.39798 | 0.142912 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9723092,"numValue":0.397979541079367,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9723093,"numValue":0.142911832460154,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13607 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,607 | train | mutant | 3,811,937 | 225 | 3,815,882 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260V | D260V | 1 | 1 | 0 | 0 | 260 | D | V | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,563 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.411827 | 0.045168 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183808,"numValue":-0.411826975428366,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183809,"numValue":0.0451684450919824,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13608 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,608 | train | mutant | 3,811,938 | 225 | 3,815,883 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260W | D260W | 1 | 1 | 0 | 0 | 260 | D | W | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,865,206 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.640028 | 0.141648 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9723094,"numValue":0.640027730335509,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9723095,"numValue":0.141648063546091,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13609 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,609 | train | mutant | 3,811,938 | 225 | 3,815,883 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260W | D260W | 1 | 1 | 0 | 0 | 260 | D | W | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,564 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.738763 | 0.045437 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183810,"numValue":-0.738762955462875,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183811,"numValue":0.0454370621513189,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13611 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,611 | train | mutant | 3,811,939 | 225 | 3,815,884 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260Y | D260Y | 1 | 1 | 0 | 0 | 260 | D | Y | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,565 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.35791 | 0.057606 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183812,"numValue":-0.357910210839089,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183813,"numValue":0.0576062289303469,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13612 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,612 | train | mutant | 4,906,065 | 225 | 4,912,653 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delD260 | delD260 | 1 | 0 | 1 | 0 | 260 | D | - | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,306 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.126234 | 0.058527 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183294,"numValue":-1.12623433085554,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183295,"numValue":0.0585268902493308,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13613 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,613 | train | mutant | 3,813,231 | 225 | 3,817,176 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261A | P261A | 1 | 1 | 0 | 0 | 261 | P | A | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,866,500 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.865549 | 0.113073 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9725682,"numValue":0.865549429395288,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9725683,"numValue":0.113073137409568,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13614 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,614 | train | mutant | 3,813,231 | 225 | 3,817,176 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261A | P261A | 1 | 1 | 0 | 0 | 261 | P | A | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,310 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.940019 | 0.053724 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183302,"numValue":-0.940019188785631,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183303,"numValue":0.0537243189541251,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13615 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,615 | train | mutant | 3,813,232 | 225 | 3,817,177 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261C | P261C | 1 | 1 | 0 | 0 | 261 | P | C | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,866,501 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.974962 | 0.100129 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9725684,"numValue":0.97496218646365,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9725685,"numValue":0.100129360685518,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13616 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,616 | train | mutant | 3,813,232 | 225 | 3,817,177 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261C | P261C | 1 | 1 | 0 | 0 | 261 | P | C | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,311 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.866496 | 0.06172 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183304,"numValue":-0.866496060340817,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183305,"numValue":0.0617197086295424,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13617 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,617 | train | mutant | 3,813,233 | 225 | 3,817,178 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261D | P261D | 1 | 1 | 0 | 0 | 261 | P | D | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,866,502 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.937759 | 0.125191 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9725686,"numValue":0.937759024831088,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9725687,"numValue":0.125190890636368,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13618 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,618 | train | mutant | 3,813,233 | 225 | 3,817,178 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261D | P261D | 1 | 1 | 0 | 0 | 261 | P | D | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,312 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.100018 | 0.074849 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183306,"numValue":-1.10001769097837,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183307,"numValue":0.0748494644624918,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13619 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,619 | train | mutant | 3,813,234 | 225 | 3,817,179 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261E | P261E | 1 | 1 | 0 | 0 | 261 | P | E | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,866,503 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.609015 | 0.117102 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9725688,"numValue":0.609015333832266,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9725689,"numValue":0.117102092167429,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13620 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,620 | train | mutant | 3,813,234 | 225 | 3,817,179 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261E | P261E | 1 | 1 | 0 | 0 | 261 | P | E | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,313 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.967112 | 0.056365 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183308,"numValue":-0.967112361002518,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183309,"numValue":0.0563645623083384,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13621 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,621 | train | mutant | 3,813,235 | 225 | 3,817,180 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261F | P261F | 1 | 1 | 0 | 0 | 261 | P | F | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,866,504 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 1.143544 | 0.068013 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9725690,"numValue":1.14354404437385,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9725691,"numValue":0.0680127656875614,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13622 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,622 | train | mutant | 3,813,235 | 225 | 3,817,180 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261F | P261F | 1 | 1 | 0 | 0 | 261 | P | F | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,314 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.828516 | 0.06398 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183310,"numValue":-0.828515856771194,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183311,"numValue":0.0639802486136461,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13623 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,623 | train | mutant | 3,813,236 | 225 | 3,817,181 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261G | P261G | 1 | 1 | 0 | 0 | 261 | P | G | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,866,505 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.738205 | 0.062961 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9725692,"numValue":0.738204976694459,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9725693,"numValue":0.0629609398417617,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13624 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,624 | train | mutant | 3,813,236 | 225 | 3,817,181 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261G | P261G | 1 | 1 | 0 | 0 | 261 | P | G | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,315 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.927894 | 0.043654 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183312,"numValue":-0.927893586045818,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183313,"numValue":0.0436535384504943,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13626 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,626 | train | mutant | 3,813,237 | 225 | 3,817,182 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261H | P261H | 1 | 1 | 0 | 0 | 261 | P | H | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,316 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.845778 | 0.092531 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183314,"numValue":-0.845778435532441,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183315,"numValue":0.0925306558453116,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13627 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,627 | train | mutant | 3,813,238 | 225 | 3,817,183 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261I | P261I | 1 | 1 | 0 | 0 | 261 | P | I | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,866,507 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.911742 | 0.113379 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9725696,"numValue":0.911741906571564,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9725697,"numValue":0.113378797386352,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13628 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,628 | train | mutant | 3,813,238 | 225 | 3,817,183 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261I | P261I | 1 | 1 | 0 | 0 | 261 | P | I | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,317 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.759034 | 0.072076 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183316,"numValue":-0.759033641078061,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183317,"numValue":0.0720756247213518,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13629 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,629 | train | mutant | 3,813,239 | 225 | 3,817,184 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261K | P261K | 1 | 1 | 0 | 0 | 261 | P | K | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,866,508 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.969472 | 0.164068 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9725698,"numValue":0.969472246108992,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9725699,"numValue":0.164068042235662,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13630 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,630 | train | mutant | 3,813,239 | 225 | 3,817,184 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261K | P261K | 1 | 1 | 0 | 0 | 261 | P | K | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,318 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.07401 | 0.068532 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183318,"numValue":-1.07401015848944,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183319,"numValue":0.0685324718968284,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13631 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,631 | train | mutant | 3,813,240 | 225 | 3,817,185 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261L | P261L | 1 | 1 | 0 | 0 | 261 | P | L | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,866,509 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.883113 | 0.089735 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9725700,"numValue":0.883113372065958,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9725701,"numValue":0.0897354361044313,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13632 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,632 | train | mutant | 3,813,240 | 225 | 3,817,185 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261L | P261L | 1 | 1 | 0 | 0 | 261 | P | L | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,319 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.614815 | 0.046867 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183320,"numValue":-0.614814948932821,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183321,"numValue":0.0468671561728992,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13634 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,634 | train | mutant | 3,813,241 | 225 | 3,817,186 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261M | P261M | 1 | 1 | 0 | 0 | 261 | P | M | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,320 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.506124 | 0.052878 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183322,"numValue":-0.506124222686749,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183323,"numValue":0.0528778477906923,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13635 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,635 | train | mutant | 3,813,242 | 225 | 3,817,187 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261N | P261N | 1 | 1 | 0 | 0 | 261 | P | N | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,866,511 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 1.112224 | 0.159903 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9725704,"numValue":1.11222406366395,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9725705,"numValue":0.159903243600478,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13636 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,636 | train | mutant | 3,813,242 | 225 | 3,817,187 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261N | P261N | 1 | 1 | 0 | 0 | 261 | P | N | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,321 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.023585 | 0.073819 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183324,"numValue":-1.02358472342105,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183325,"numValue":0.0738194355235968,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13637 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,637 | train | mutant | 3,813,243 | 225 | 3,817,188 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261Q | P261Q | 1 | 1 | 0 | 0 | 261 | P | Q | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,866,512 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.733679 | 0.195303 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9725706,"numValue":0.733678917966698,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9725707,"numValue":0.195303491864841,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13638 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,638 | train | mutant | 3,813,243 | 225 | 3,817,188 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261Q | P261Q | 1 | 1 | 0 | 0 | 261 | P | Q | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,542 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.835638 | 0.060355 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183766,"numValue":-0.835638398152586,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183767,"numValue":0.060354908946921,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13639 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,639 | train | mutant | 3,813,244 | 225 | 3,817,189 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261R | P261R | 1 | 1 | 0 | 0 | 261 | P | R | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,866,513 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.950483 | 0.164809 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9725708,"numValue":0.950483248051953,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9725709,"numValue":0.164808780714172,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13641 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,641 | train | mutant | 3,813,245 | 225 | 3,817,190 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261S | P261S | 1 | 1 | 0 | 0 | 261 | P | S | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,866,514 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.833486 | 0.081879 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9725710,"numValue":0.833486358370367,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9725711,"numValue":0.0818786254896088,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13642 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,642 | train | mutant | 3,813,245 | 225 | 3,817,190 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261S | P261S | 1 | 1 | 0 | 0 | 261 | P | S | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,544 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.977477 | 0.048333 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183770,"numValue":-0.97747654431565,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183771,"numValue":0.0483326504520994,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13643 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,643 | train | mutant | 3,813,246 | 225 | 3,817,191 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261T | P261T | 1 | 1 | 0 | 0 | 261 | P | T | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,866,515 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.894657 | 0.098581 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9725712,"numValue":0.89465747973459,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9725713,"numValue":0.0985810308064319,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13644 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,644 | train | mutant | 3,813,246 | 225 | 3,817,191 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261T | P261T | 1 | 1 | 0 | 0 | 261 | P | T | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,545 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.956722 | 0.062331 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183772,"numValue":-0.956722476895474,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183773,"numValue":0.0623309021536044,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13645 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,645 | train | mutant | 3,813,247 | 225 | 3,817,192 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261V | P261V | 1 | 1 | 0 | 0 | 261 | P | V | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,866,516 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.800497 | 0.082625 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9725714,"numValue":0.800497440203752,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9725715,"numValue":0.0826247990735484,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13646 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,646 | train | mutant | 3,813,247 | 225 | 3,817,192 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261V | P261V | 1 | 1 | 0 | 0 | 261 | P | V | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,546 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.606351 | 0.045805 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183774,"numValue":-0.606350714712622,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183775,"numValue":0.045804949521751,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13647 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,647 | train | mutant | 3,813,248 | 225 | 3,817,193 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261W | P261W | 1 | 1 | 0 | 0 | 261 | P | W | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,866,517 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 1.100551 | 0.155801 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9725716,"numValue":1.10055089756017,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9725717,"numValue":0.155801089337814,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13648 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,648 | train | mutant | 3,813,248 | 225 | 3,817,193 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261W | P261W | 1 | 1 | 0 | 0 | 261 | P | W | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,547 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.890173 | 0.049279 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183776,"numValue":-0.890172618347909,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183777,"numValue":0.0492792990134718,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13649 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,649 | train | mutant | 3,813,249 | 225 | 3,817,194 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261Y | P261Y | 1 | 1 | 0 | 0 | 261 | P | Y | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,866,518 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 1.176246 | 0.153911 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9725718,"numValue":1.17624604973893,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9725719,"numValue":0.153911450591672,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13650 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,650 | train | mutant | 3,813,249 | 225 | 3,817,194 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P261Y | P261Y | 1 | 1 | 0 | 0 | 261 | P | Y | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,548 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.165431 | 0.104466 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183778,"numValue":-1.1654306275637,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183779,"numValue":0.104466247762027,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16925,"numValue":8.0,"position":261,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13652 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,652 | train | mutant | 4,906,067 | 225 | 4,912,655 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delR262 | delR262 | 1 | 0 | 1 | 0 | 262 | R | - | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,322 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.151265 | 0.077524 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183326,"numValue":-1.15126526500345,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183327,"numValue":0.077524431737643,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16926,"numValue":8.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13653 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,653 | train | mutant | 4,906,068 | 225 | 4,912,656 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | R262A | R262A | 1 | 1 | 0 | 0 | 262 | R | A | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,323 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.347348 | 0.050807 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183328,"numValue":-0.347348218938761,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183329,"numValue":0.0508068014310473,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16926,"numValue":8.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13654 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,654 | train | mutant | 4,906,069 | 225 | 4,912,657 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | R262C | R262C | 1 | 1 | 0 | 0 | 262 | R | C | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,324 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.382488 | 0.058565 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183330,"numValue":-0.382488285858616,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183331,"numValue":0.0585647810173204,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16926,"numValue":8.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13655 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,655 | train | mutant | 4,906,070 | 225 | 4,912,658 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | R262D | R262D | 1 | 1 | 0 | 0 | 262 | R | D | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,325 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.742943 | 0.083046 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183332,"numValue":-0.742942795725917,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183333,"numValue":0.0830457897876447,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16926,"numValue":8.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13656 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,656 | train | mutant | 4,906,071 | 225 | 4,912,659 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | R262E | R262E | 1 | 1 | 0 | 0 | 262 | R | E | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,326 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.67593 | 0.05238 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183334,"numValue":-0.675929606766753,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183335,"numValue":0.052380207217067,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16926,"numValue":8.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13657 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,657 | train | mutant | 4,906,072 | 225 | 4,912,660 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | R262F | R262F | 1 | 1 | 0 | 0 | 262 | R | F | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,327 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.501534 | 0.072918 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183336,"numValue":-0.501533806273296,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183337,"numValue":0.0729175365798584,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16926,"numValue":8.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13658 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,658 | train | mutant | 4,906,073 | 225 | 4,912,661 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | R262G | R262G | 1 | 1 | 0 | 0 | 262 | R | G | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,328 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.303943 | 0.043041 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183338,"numValue":-0.303943317766331,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183339,"numValue":0.0430411593480135,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16926,"numValue":8.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13659 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,659 | train | mutant | 4,906,074 | 225 | 4,912,662 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | R262H | R262H | 1 | 1 | 0 | 0 | 262 | R | H | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,329 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.524451 | 0.081904 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183340,"numValue":-0.524451116678211,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183341,"numValue":0.0819042926066737,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16926,"numValue":8.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13660 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,660 | train | mutant | 4,906,075 | 225 | 4,912,663 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | R262I | R262I | 1 | 1 | 0 | 0 | 262 | R | I | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,330 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.739381 | 0.072659 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183342,"numValue":-0.739380808914028,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183343,"numValue":0.072659279407108,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16926,"numValue":8.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13661 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,661 | train | mutant | 4,906,076 | 225 | 4,912,664 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | R262K | R262K | 1 | 1 | 0 | 0 | 262 | R | K | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,331 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.271267 | 0.059607 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183344,"numValue":-0.271266707748948,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183345,"numValue":0.0596074534737155,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16926,"numValue":8.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13662 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,662 | train | mutant | 4,906,077 | 225 | 4,912,665 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | R262L | R262L | 1 | 1 | 0 | 0 | 262 | R | L | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,332 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.411141 | 0.048918 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183346,"numValue":-0.411141090463918,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183347,"numValue":0.0489181033977392,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16926,"numValue":8.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13663 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,663 | train | mutant | 4,906,078 | 225 | 4,912,666 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | R262M | R262M | 1 | 1 | 0 | 0 | 262 | R | M | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,333 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.482466 | 0.059339 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183348,"numValue":-0.482465726847514,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183349,"numValue":0.059339114905954,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16926,"numValue":8.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13664 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,664 | train | mutant | 4,906,079 | 225 | 4,912,667 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | R262N | R262N | 1 | 1 | 0 | 0 | 262 | R | N | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,334 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.491242 | 0.072648 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183350,"numValue":-0.491241632924528,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183351,"numValue":0.0726481079165038,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16926,"numValue":8.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13665 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,665 | train | mutant | 4,906,080 | 225 | 4,912,668 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | R262P | R262P | 1 | 1 | 0 | 0 | 262 | R | P | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,335 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.962927 | 0.065991 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183352,"numValue":-0.962927030477,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183353,"numValue":0.0659913078880594,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16926,"numValue":8.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13667 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,667 | train | mutant | 4,906,282 | 225 | 4,912,870 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | R262S | R262S | 1 | 1 | 0 | 0 | 262 | R | S | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,537 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.191056 | 0.050725 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183756,"numValue":-0.191055564348595,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183757,"numValue":0.0507246464164542,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16926,"numValue":8.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13668 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,668 | train | mutant | 4,906,283 | 225 | 4,912,871 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | R262T | R262T | 1 | 1 | 0 | 0 | 262 | R | T | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,538 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.245478 | 0.078748 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183758,"numValue":-0.245478387913962,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183759,"numValue":0.078747678131198,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16926,"numValue":8.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13669 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,669 | train | mutant | 4,906,284 | 225 | 4,912,872 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | R262V | R262V | 1 | 1 | 0 | 0 | 262 | R | V | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,539 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.42934 | 0.050072 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183760,"numValue":-0.429339639623866,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183761,"numValue":0.0500719019494184,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16926,"numValue":8.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13670 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,670 | train | mutant | 4,906,285 | 225 | 4,912,873 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | R262W | R262W | 1 | 1 | 0 | 0 | 262 | R | W | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,540 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.503656 | 0.046716 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183762,"numValue":-0.503655593797886,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183763,"numValue":0.0467164206187635,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16926,"numValue":8.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13671 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,671 | train | mutant | 4,906,286 | 225 | 4,912,874 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | R262Y | R262Y | 1 | 1 | 0 | 0 | 262 | R | Y | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,541 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.683649 | 0.09544 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183764,"numValue":-0.68364907494667,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183765,"numValue":0.0954399379746747,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16926,"numValue":8.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13672 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,672 | train | mutant | 4,906,082 | 225 | 4,912,670 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delL263 | delL263 | 1 | 0 | 1 | 0 | 263 | L | - | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,337 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.266814 | 0.086856 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183356,"numValue":-1.26681440326439,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183357,"numValue":0.0868555545321653,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16927,"numValue":7.0,"position":263,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13673 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,673 | train | mutant | 4,906,083 | 225 | 4,912,671 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L263A | L263A | 1 | 1 | 0 | 0 | 263 | L | A | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,338 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.046804 | 0.045192 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183358,"numValue":0.0468040897665395,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183359,"numValue":0.0451921884879675,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16927,"numValue":7.0,"position":263,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13675 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,675 | train | mutant | 4,906,085 | 225 | 4,912,673 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L263D | L263D | 1 | 1 | 0 | 0 | 263 | L | D | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,340 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.084622 | 0.059833 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183362,"numValue":0.0846216542564257,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183363,"numValue":0.0598333817530721,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16927,"numValue":7.0,"position":263,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13676 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,676 | train | mutant | 4,906,086 | 225 | 4,912,674 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L263E | L263E | 1 | 1 | 0 | 0 | 263 | L | E | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,341 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.03491 | 0.050966 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183364,"numValue":0.0349101124480153,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183365,"numValue":0.0509658042065062,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16927,"numValue":7.0,"position":263,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13678 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,678 | train | mutant | 4,906,088 | 225 | 4,912,676 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L263G | L263G | 1 | 1 | 0 | 0 | 263 | L | G | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,343 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.089038 | 0.042551 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183368,"numValue":0.0890377349439966,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183369,"numValue":0.0425505367620755,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16927,"numValue":7.0,"position":263,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13679 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,679 | train | mutant | 4,906,089 | 225 | 4,912,677 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L263H | L263H | 1 | 1 | 0 | 0 | 263 | L | H | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,344 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.014264 | 0.057689 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183370,"numValue":0.014264338465961,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183371,"numValue":0.0576891557644476,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16927,"numValue":7.0,"position":263,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13680 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,680 | train | mutant | 4,906,090 | 225 | 4,912,678 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L263I | L263I | 1 | 1 | 0 | 0 | 263 | L | I | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,345 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.030768 | 0.061211 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183372,"numValue":0.0307677491940524,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183373,"numValue":0.0612105464616187,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16927,"numValue":7.0,"position":263,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13682 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,682 | train | mutant | 4,906,272 | 225 | 4,912,860 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L263M | L263M | 1 | 1 | 0 | 0 | 263 | L | M | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,527 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.0093 | 0.058171 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183736,"numValue":-0.00930002722096005,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183737,"numValue":0.0581713201634111,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16927,"numValue":7.0,"position":263,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13683 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,683 | train | mutant | 4,906,273 | 225 | 4,912,861 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L263N | L263N | 1 | 1 | 0 | 0 | 263 | L | N | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,528 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.123266 | 0.066673 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183738,"numValue":0.123265940878634,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183739,"numValue":0.0666731984876332,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16927,"numValue":7.0,"position":263,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13685 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,685 | train | mutant | 4,906,275 | 225 | 4,912,863 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L263Q | L263Q | 1 | 1 | 0 | 0 | 263 | L | Q | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,530 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.042079 | 0.057639 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183742,"numValue":0.0420792812759456,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183743,"numValue":0.0576388840567285,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16927,"numValue":7.0,"position":263,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13687 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,687 | train | mutant | 4,906,277 | 225 | 4,912,865 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L263S | L263S | 1 | 1 | 0 | 0 | 263 | L | S | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,532 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.13834 | 0.045792 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183746,"numValue":0.138340291982423,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183747,"numValue":0.045792481056098,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16927,"numValue":7.0,"position":263,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13690 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,690 | train | mutant | 4,906,280 | 225 | 4,912,868 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L263W | L263W | 1 | 1 | 0 | 0 | 263 | L | W | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,535 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.103809 | 0.045935 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183752,"numValue":-0.10380892807626,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183753,"numValue":0.0459352676649961,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16927,"numValue":7.0,"position":263,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13691 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,691 | train | mutant | 4,906,281 | 225 | 4,912,869 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L263Y | L263Y | 1 | 1 | 0 | 0 | 263 | L | Y | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,536 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.040571 | 0.058327 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183754,"numValue":-0.0405714483204596,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183755,"numValue":0.0583272515746441,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16927,"numValue":7.0,"position":263,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13692 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,692 | train | mutant | 4,906,092 | 225 | 4,912,680 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delD264 | delD264 | 1 | 0 | 1 | 0 | 264 | D | - | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,347 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.229218 | 0.06441 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183376,"numValue":-1.22921785366679,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183377,"numValue":0.0644104703554411,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16928,"numValue":4.0,"position":264,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13694 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,694 | train | mutant | 4,906,094 | 225 | 4,912,682 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D264C | D264C | 1 | 1 | 0 | 0 | 264 | D | C | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,349 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.256932 | 0.05416 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183380,"numValue":0.256932348544157,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183381,"numValue":0.0541599195617666,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16928,"numValue":4.0,"position":264,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13695 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,695 | train | mutant | 4,906,255 | 225 | 4,912,843 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D264E | D264E | 1 | 1 | 0 | 0 | 264 | D | E | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,510 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.067225 | 0.047587 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183702,"numValue":0.0672246834180383,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183703,"numValue":0.0475865396953556,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16928,"numValue":4.0,"position":264,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13696 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,696 | train | mutant | 4,906,256 | 225 | 4,912,844 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D264F | D264F | 1 | 1 | 0 | 0 | 264 | D | F | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,511 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.098487 | 0.051949 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183704,"numValue":0.0984865562349703,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183705,"numValue":0.0519491500005472,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16928,"numValue":4.0,"position":264,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13697 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,697 | train | mutant | 4,906,257 | 225 | 4,912,845 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D264G | D264G | 1 | 1 | 0 | 0 | 264 | D | G | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,512 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.004094 | 0.042712 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183706,"numValue":-0.0040938261509103,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183707,"numValue":0.0427119106943721,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16928,"numValue":4.0,"position":264,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13698 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,698 | train | mutant | 4,906,258 | 225 | 4,912,846 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D264H | D264H | 1 | 1 | 0 | 0 | 264 | D | H | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,513 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.095011 | 0.057311 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183708,"numValue":0.0950109813803199,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183709,"numValue":0.0573109085074295,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16928,"numValue":4.0,"position":264,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13699 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,699 | train | mutant | 4,906,259 | 225 | 4,912,847 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D264I | D264I | 1 | 1 | 0 | 0 | 264 | D | I | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,514 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.071353 | 0.062318 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183710,"numValue":0.0713527242481497,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183711,"numValue":0.0623182665930064,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16928,"numValue":4.0,"position":264,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13700 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,700 | train | mutant | 4,906,260 | 225 | 4,912,848 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D264K | D264K | 1 | 1 | 0 | 0 | 264 | D | K | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,515 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.024255 | 0.053951 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183712,"numValue":0.0242550247926528,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183713,"numValue":0.0539508440011421,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16928,"numValue":4.0,"position":264,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13701 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,701 | train | mutant | 4,906,261 | 225 | 4,912,849 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D264L | D264L | 1 | 1 | 0 | 0 | 264 | D | L | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,516 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.112273 | 0.042863 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183714,"numValue":0.112272684882331,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183715,"numValue":0.0428628213003549,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16928,"numValue":4.0,"position":264,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13702 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,702 | train | mutant | 4,906,262 | 225 | 4,912,850 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D264M | D264M | 1 | 1 | 0 | 0 | 264 | D | M | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,517 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.105699 | 0.053422 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183716,"numValue":0.105699488024669,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183717,"numValue":0.0534218054916732,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16928,"numValue":4.0,"position":264,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13703 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,703 | train | mutant | 4,906,263 | 225 | 4,912,851 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D264N | D264N | 1 | 1 | 0 | 0 | 264 | D | N | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,518 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.000073 | 0.055055 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183718,"numValue":-0.0000732034996857561,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183719,"numValue":0.0550545061124385,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16928,"numValue":4.0,"position":264,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13704 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,704 | train | mutant | 4,906,264 | 225 | 4,912,852 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D264P | D264P | 1 | 1 | 0 | 0 | 264 | D | P | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,519 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.059691 | 0.052245 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183720,"numValue":-0.0596910884721066,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183721,"numValue":0.0522448205271588,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16928,"numValue":4.0,"position":264,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13705 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,705 | train | mutant | 4,906,265 | 225 | 4,912,853 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D264Q | D264Q | 1 | 1 | 0 | 0 | 264 | D | Q | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,520 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.104738 | 0.051527 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183722,"numValue":0.104738294246186,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183723,"numValue":0.0515272352645861,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16928,"numValue":4.0,"position":264,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13706 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,706 | train | mutant | 4,906,266 | 225 | 4,912,854 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D264R | D264R | 1 | 1 | 0 | 0 | 264 | D | R | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,521 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.108497 | 0.043864 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183724,"numValue":-0.108497134817012,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183725,"numValue":0.043863990555189,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16928,"numValue":4.0,"position":264,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13707 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,707 | train | mutant | 4,906,267 | 225 | 4,912,855 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D264S | D264S | 1 | 1 | 0 | 0 | 264 | D | S | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,522 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.017449 | 0.044006 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183726,"numValue":-0.0174494863925098,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183727,"numValue":0.0440061087843074,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16928,"numValue":4.0,"position":264,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13708 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,708 | train | mutant | 4,906,268 | 225 | 4,912,856 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D264T | D264T | 1 | 1 | 0 | 0 | 264 | D | T | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,523 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.003273 | 0.050012 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183728,"numValue":0.00327346954030033,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183729,"numValue":0.0500121535712508,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16928,"numValue":4.0,"position":264,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13709 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,709 | train | mutant | 4,906,269 | 225 | 4,912,857 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D264V | D264V | 1 | 1 | 0 | 0 | 264 | D | V | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,524 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.071341 | 0.043999 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183730,"numValue":0.07134078889494,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183731,"numValue":0.0439993215467822,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16928,"numValue":4.0,"position":264,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13710 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,710 | train | mutant | 4,906,270 | 225 | 4,912,858 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D264W | D264W | 1 | 1 | 0 | 0 | 264 | D | W | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,525 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.223431 | 0.047072 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183732,"numValue":0.223431403465095,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183733,"numValue":0.0470715292043592,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16928,"numValue":4.0,"position":264,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13711 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,711 | train | mutant | 4,906,271 | 225 | 4,912,859 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D264Y | D264Y | 1 | 1 | 0 | 0 | 264 | D | Y | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,526 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.026061 | 0.051912 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183734,"numValue":0.02606124157838,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183735,"numValue":0.0519118560002181,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16928,"numValue":4.0,"position":264,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13712 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,712 | train | mutant | 4,906,095 | 225 | 4,912,683 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delP265 | delP265 | 1 | 0 | 1 | 0 | 265 | P | - | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,350 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.129379 | 0.076947 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183382,"numValue":-1.12937929642629,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183383,"numValue":0.0769469754786537,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16929,"numValue":2.0,"position":265,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13713 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,713 | train | mutant | 4,906,096 | 225 | 4,912,684 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P265A | P265A | 1 | 1 | 0 | 0 | 265 | P | A | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,351 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.033826 | 0.044888 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183384,"numValue":0.033826382376579,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183385,"numValue":0.0448877335413936,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16929,"numValue":2.0,"position":265,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13714 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,714 | train | mutant | 4,906,097 | 225 | 4,912,685 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P265C | P265C | 1 | 1 | 0 | 0 | 265 | P | C | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,352 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.005498 | 0.0466 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183386,"numValue":0.00549821937857921,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183387,"numValue":0.0466004010286635,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16929,"numValue":2.0,"position":265,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13715 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,715 | train | mutant | 4,906,098 | 225 | 4,912,686 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P265D | P265D | 1 | 1 | 0 | 0 | 265 | P | D | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,353 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.124946 | 0.052098 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183388,"numValue":0.124945642920339,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183389,"numValue":0.0520983817001786,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16929,"numValue":2.0,"position":265,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13716 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,716 | train | mutant | 4,906,099 | 225 | 4,912,687 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P265E | P265E | 1 | 1 | 0 | 0 | 265 | P | E | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,354 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.064655 | 0.052308 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183390,"numValue":0.0646546040268936,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183391,"numValue":0.0523078869335186,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16929,"numValue":2.0,"position":265,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13717 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,717 | train | mutant | 4,906,100 | 225 | 4,912,688 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P265F | P265F | 1 | 1 | 0 | 0 | 265 | P | F | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,355 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.059474 | 0.049819 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183392,"numValue":0.0594738650436909,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183393,"numValue":0.049818944073493,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16929,"numValue":2.0,"position":265,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13718 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,718 | train | mutant | 4,906,101 | 225 | 4,912,689 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P265G | P265G | 1 | 1 | 0 | 0 | 265 | P | G | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,356 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.088055 | 0.043263 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183394,"numValue":0.0880550575297353,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183395,"numValue":0.043262926167551,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16929,"numValue":2.0,"position":265,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13720 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,720 | train | mutant | 4,906,103 | 225 | 4,912,691 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | P265I | P265I | 1 | 1 | 0 | 0 | 265 | P | I | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,358 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.067984 | 0.051414 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183398,"numValue":0.0679837718821721,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183399,"numValue":0.0514144859612656,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16929,"numValue":2.0,"position":265,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] |
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