row_id string | dataset_id string | source_dataset string | source_file string | source_table string | source_sha string | row_index int64 | split string | subject_type string | entry_id int64 | sequence_id int64 | target_sequence_id int64 | source_sequence_length int64 | target_sequence_length int64 | protein_id int64 | protein_name string | organism string | isoform int64 | protein_ids string | protein_names string | organisms string | isoforms string | uniprot_accessions string | interpro_accessions string | ec_numbers string | megascale_ids string | other_references string | mutations string | substitutions string | deletions string | insertions string | mutation_count int64 | substitution_count int64 | deletion_count int64 | insertion_count int64 | first_position int64 | first_source_aa string | first_target_aa string | conservation float64 | feature_types string | pdb_ids string | afdb_ids string | structure_ids string | structure_methods string | structure_resolution_min float64 | residue_positions string | residue_chain_names string | residue_secondary_structures string | residue_in_pocket_any bool | residue_in_tunnel_any bool | residue_asa_mean float64 | residue_bfactor_mean float64 | experiment_id int64 | experiment_dataset string | ph float64 | measure string | method string | buffer string | buffer_conc string | exp_temperature float64 | ion string | ion_conc string | pdb_chain_mutation string | tm float64 | dtm float64 | dg float64 | dg_text string | ddg float64 | dh float64 | dcp float64 | dhvh float64 | cm float64 | m_value float64 | trypsin_ml float64 | chymotrypsin_ml float64 | stabilizing float64 | stabilizing_text string | domainome_fitness float64 | domainome_fitness_std float64 | domainome_ddg float64 | domainome_ddg_std float64 | reversibility string | state string | measurement_types string | measurement_datasets string | annotation_types string | publication_id string | publication_type string | publication_title string | publication_year int64 | publication_doi string | publication_pmid string | publication_journal string | publication_url string | publication_author_count int64 | publication_authors string | annotations_json string | measurements_json string | features_json string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fireprotdb:13501 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,501 | train | mutant | 3,809,304 | 225 | 3,813,249 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258D | W258D | 1 | 1 | 0 | 0 | 258 | W | D | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,280 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.630616 | 0.107844 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183242,"numValue":-0.630616003909035,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183243,"numValue":0.107844191427422,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13502 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,502 | train | mutant | 3,809,305 | 225 | 3,813,250 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258E | W258E | 1 | 1 | 0 | 0 | 258 | W | E | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,862,570 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.085326 | 0.069228 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9717822,"numValue":0.085326254649021,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9717823,"numValue":0.0692280721408498,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13503 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,503 | train | mutant | 3,809,305 | 225 | 3,813,250 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258E | W258E | 1 | 1 | 0 | 0 | 258 | W | E | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,281 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.961587 | 0.200571 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183244,"numValue":-0.961586690311556,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183245,"numValue":0.200570984910479,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13504 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,504 | train | mutant | 3,809,306 | 225 | 3,813,251 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258F | W258F | 1 | 1 | 0 | 0 | 258 | W | F | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,862,571 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.097071 | 0.100966 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9717824,"numValue":-0.0970713093056677,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9717825,"numValue":0.100966378174496,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13505 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,505 | train | mutant | 3,809,306 | 225 | 3,813,251 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258F | W258F | 1 | 1 | 0 | 0 | 258 | W | F | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,282 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.005649 | 0.072707 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183246,"numValue":0.00564940051923494,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183247,"numValue":0.0727065991041332,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13506 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,506 | train | mutant | 3,809,307 | 225 | 3,813,252 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258G | W258G | 1 | 1 | 0 | 0 | 258 | W | G | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,862,572 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.259826 | 0.05789 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9717826,"numValue":0.25982578895951,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9717827,"numValue":0.0578904557178814,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13507 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,507 | train | mutant | 3,809,307 | 225 | 3,813,252 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258G | W258G | 1 | 1 | 0 | 0 | 258 | W | G | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,283 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.702527 | 0.093895 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183248,"numValue":-0.702527382256418,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183249,"numValue":0.0938951849932603,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13508 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,508 | train | mutant | 3,809,308 | 225 | 3,813,253 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258H | W258H | 1 | 1 | 0 | 0 | 258 | W | H | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,862,573 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.149514 | 0.090833 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9717828,"numValue":0.149513662602613,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9717829,"numValue":0.0908334736877105,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13509 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,509 | train | mutant | 3,809,308 | 225 | 3,813,253 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258H | W258H | 1 | 1 | 0 | 0 | 258 | W | H | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,284 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.383183 | 0.069138 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183250,"numValue":-0.383182923415418,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183251,"numValue":0.0691381512877074,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13510 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,510 | train | mutant | 3,809,309 | 225 | 3,813,254 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258I | W258I | 1 | 1 | 0 | 0 | 258 | W | I | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,862,574 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.234811 | 0.08862 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9717830,"numValue":0.234810688087341,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9717831,"numValue":0.0886202942556177,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13511 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,511 | train | mutant | 3,809,309 | 225 | 3,813,254 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258I | W258I | 1 | 1 | 0 | 0 | 258 | W | I | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,285 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.477439 | 0.077777 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183252,"numValue":-0.477438794782674,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183253,"numValue":0.0777765302681373,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13513 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,513 | train | mutant | 3,809,310 | 225 | 3,813,255 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258K | W258K | 1 | 1 | 0 | 0 | 258 | W | K | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,286 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.613414 | 0.113204 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183254,"numValue":-0.6134144545872,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183255,"numValue":0.113203960708769,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13515 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,515 | train | mutant | 3,809,311 | 225 | 3,813,256 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258L | W258L | 1 | 1 | 0 | 0 | 258 | W | L | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,287 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.433789 | 0.056625 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183256,"numValue":-0.433788502748252,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183257,"numValue":0.0566248325773302,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13516 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,516 | train | mutant | 3,809,312 | 225 | 3,813,257 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258M | W258M | 1 | 1 | 0 | 0 | 258 | W | M | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,862,577 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.085156 | 0.072719 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9717836,"numValue":0.0851559377996812,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9717837,"numValue":0.0727188749420883,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13517 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,517 | train | mutant | 3,809,312 | 225 | 3,813,257 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258M | W258M | 1 | 1 | 0 | 0 | 258 | W | M | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,288 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.319233 | 0.104637 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183258,"numValue":-0.319232505227894,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183259,"numValue":0.104637400727053,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13518 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,518 | train | mutant | 3,809,313 | 225 | 3,813,258 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258N | W258N | 1 | 1 | 0 | 0 | 258 | W | N | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,862,578 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.228551 | 0.089034 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9717838,"numValue":0.228550515648932,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9717839,"numValue":0.0890339474142004,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13519 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,519 | train | mutant | 3,809,313 | 225 | 3,813,258 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258N | W258N | 1 | 1 | 0 | 0 | 258 | W | N | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,289 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.267352 | 0.073715 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183260,"numValue":-0.267351911896183,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183261,"numValue":0.0737149454846973,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13520 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,520 | train | mutant | 3,809,314 | 225 | 3,813,259 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258P | W258P | 1 | 1 | 0 | 0 | 258 | W | P | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,862,579 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.257634 | 0.10495 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9717840,"numValue":0.257633877331273,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9717841,"numValue":0.104949500252408,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13521 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,521 | train | mutant | 3,809,314 | 225 | 3,813,259 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258P | W258P | 1 | 1 | 0 | 0 | 258 | W | P | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,290 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.5446 | 0.072353 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183262,"numValue":-0.544600379966744,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183263,"numValue":0.0723533365198339,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13522 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,522 | train | mutant | 3,809,315 | 225 | 3,813,260 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258Q | W258Q | 1 | 1 | 0 | 0 | 258 | W | Q | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,862,580 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.128469 | 0.08123 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9717842,"numValue":0.128469373238293,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9717843,"numValue":0.0812304807275134,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13523 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,523 | train | mutant | 3,809,315 | 225 | 3,813,260 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258Q | W258Q | 1 | 1 | 0 | 0 | 258 | W | Q | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,291 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.724207 | 0.427566 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183264,"numValue":-0.724206757826428,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183265,"numValue":0.427566364412997,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13524 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,524 | train | mutant | 3,809,316 | 225 | 3,813,261 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258R | W258R | 1 | 1 | 0 | 0 | 258 | W | R | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,862,581 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.180276 | 0.058397 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9717844,"numValue":0.18027556038542,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9717845,"numValue":0.058397196591074,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13525 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,525 | train | mutant | 3,809,316 | 225 | 3,813,261 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258R | W258R | 1 | 1 | 0 | 0 | 258 | W | R | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,292 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.370687 | 0.075639 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183266,"numValue":-0.370687404295127,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183267,"numValue":0.075639258611983,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13526 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,526 | train | mutant | 3,809,317 | 225 | 3,813,262 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258S | W258S | 1 | 1 | 0 | 0 | 258 | W | S | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,862,582 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.114548 | 0.07064 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9717846,"numValue":0.114547615121086,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9717847,"numValue":0.0706404028538854,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13527 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,527 | train | mutant | 3,809,317 | 225 | 3,813,262 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258S | W258S | 1 | 1 | 0 | 0 | 258 | W | S | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,293 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.414477 | 0.066056 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183268,"numValue":-0.414476623840909,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183269,"numValue":0.0660555678297402,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13528 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,528 | train | mutant | 3,809,318 | 225 | 3,813,263 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258T | W258T | 1 | 1 | 0 | 0 | 258 | W | T | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,862,583 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.00061 | 0.094187 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9717848,"numValue":-0.00061026916651839,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9717849,"numValue":0.0941866692968826,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13529 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,529 | train | mutant | 3,809,318 | 225 | 3,813,263 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258T | W258T | 1 | 1 | 0 | 0 | 258 | W | T | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,294 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.404624 | 0.081791 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183270,"numValue":-0.404624387611449,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183271,"numValue":0.0817908271821606,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13530 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,530 | train | mutant | 3,809,319 | 225 | 3,813,264 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258V | W258V | 1 | 1 | 0 | 0 | 258 | W | V | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,862,584 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.185753 | 0.103799 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9717850,"numValue":0.185752706299346,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9717851,"numValue":0.103798822041386,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13531 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,531 | train | mutant | 3,809,319 | 225 | 3,813,264 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258V | W258V | 1 | 1 | 0 | 0 | 258 | W | V | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,295 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.448889 | 0.080455 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183272,"numValue":-0.448889429905188,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183273,"numValue":0.0804548633128937,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13532 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,532 | train | mutant | 3,809,320 | 225 | 3,813,265 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258Y | W258Y | 1 | 1 | 0 | 0 | 258 | W | Y | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,862,585 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.146254 | 0.100057 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9717852,"numValue":-0.146254050956807,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9717853,"numValue":0.100057365230985,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13533 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,533 | train | mutant | 3,809,320 | 225 | 3,813,265 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258Y | W258Y | 1 | 1 | 0 | 0 | 258 | W | Y | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,576 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.157094 | 0.074362 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183834,"numValue":-0.15709391463564,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183835,"numValue":0.0743619371114861,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13534 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,534 | train | mutant | 4,906,063 | 225 | 4,912,651 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delW258 | delW258 | 1 | 0 | 1 | 0 | 258 | W | - | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,277 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.994008 | 0.128497 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183236,"numValue":-0.994008202046338,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183237,"numValue":0.128497285759445,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13535 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,535 | train | mutant | 3,810,611 | 225 | 3,814,556 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259A | L259A | 1 | 1 | 0 | 0 | 259 | L | A | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,863,878 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.024797 | 0.089785 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9720438,"numValue":-0.0247973872028095,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9720439,"numValue":0.0897852567789229,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13536 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,536 | train | mutant | 3,810,611 | 225 | 3,814,556 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259A | L259A | 1 | 1 | 0 | 0 | 259 | L | A | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,297 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.096384 | 0.066139 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183276,"numValue":-0.0963843426896436,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183277,"numValue":0.066138558319058,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13537 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,537 | train | mutant | 3,810,612 | 225 | 3,814,557 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259C | L259C | 1 | 1 | 0 | 0 | 259 | L | C | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,863,879 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.072115 | 0.09091 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9720440,"numValue":-0.0721147342789221,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9720441,"numValue":0.0909096326805638,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13538 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,538 | train | mutant | 3,810,612 | 225 | 3,814,557 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259C | L259C | 1 | 1 | 0 | 0 | 259 | L | C | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,298 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.050506 | 0.059819 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183278,"numValue":-0.0505064363321732,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183279,"numValue":0.0598193776053061,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13539 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,539 | train | mutant | 3,810,613 | 225 | 3,814,558 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259D | L259D | 1 | 1 | 0 | 0 | 259 | L | D | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,863,880 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.010423 | 0.062025 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9720442,"numValue":0.0104234868284451,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9720443,"numValue":0.0620251272148316,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13540 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,540 | train | mutant | 3,810,613 | 225 | 3,814,558 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259D | L259D | 1 | 1 | 0 | 0 | 259 | L | D | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,299 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.312985 | 0.081392 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183280,"numValue":-0.312984745667748,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183281,"numValue":0.0813917885398513,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13541 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,541 | train | mutant | 3,810,614 | 225 | 3,814,559 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259E | L259E | 1 | 1 | 0 | 0 | 259 | L | E | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,863,881 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.13185 | 0.112033 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9720444,"numValue":-0.131849502439279,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9720445,"numValue":0.112033096789818,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13542 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,542 | train | mutant | 3,810,614 | 225 | 3,814,559 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259E | L259E | 1 | 1 | 0 | 0 | 259 | L | E | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,300 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.44361 | 0.137149 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183282,"numValue":-0.443609547921324,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183283,"numValue":0.137149302870143,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13543 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,543 | train | mutant | 3,810,615 | 225 | 3,814,560 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259F | L259F | 1 | 1 | 0 | 0 | 259 | L | F | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,863,882 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.008921 | 0.111869 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9720446,"numValue":-0.00892060253277218,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9720447,"numValue":0.111868524498081,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13544 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,544 | train | mutant | 3,810,615 | 225 | 3,814,560 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259F | L259F | 1 | 1 | 0 | 0 | 259 | L | F | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,301 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.034655 | 0.05457 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183284,"numValue":0.0346546958893287,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183285,"numValue":0.0545698512031053,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13545 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,545 | train | mutant | 3,810,616 | 225 | 3,814,561 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259G | L259G | 1 | 1 | 0 | 0 | 259 | L | G | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,863,883 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.138583 | 0.077044 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9720448,"numValue":0.138582793491018,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9720449,"numValue":0.0770440148138513,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13546 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,546 | train | mutant | 3,810,616 | 225 | 3,814,561 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259G | L259G | 1 | 1 | 0 | 0 | 259 | L | G | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,302 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.143037 | 0.065324 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183286,"numValue":-0.143037251315528,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183287,"numValue":0.0653238829365757,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13547 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,547 | train | mutant | 3,810,617 | 225 | 3,814,562 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259H | L259H | 1 | 1 | 0 | 0 | 259 | L | H | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,863,884 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.140357 | 0.091978 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9720450,"numValue":-0.140356984071205,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9720451,"numValue":0.0919784129675341,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13548 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,548 | train | mutant | 3,810,617 | 225 | 3,814,562 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259H | L259H | 1 | 1 | 0 | 0 | 259 | L | H | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,303 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.010809 | 0.058726 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183288,"numValue":0.01080865586666,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183289,"numValue":0.0587256934492929,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13549 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,549 | train | mutant | 3,810,618 | 225 | 3,814,563 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259I | L259I | 1 | 1 | 0 | 0 | 259 | L | I | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,863,885 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.11151 | 0.181368 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9720452,"numValue":-0.111510331920493,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9720453,"numValue":0.181367825279081,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13550 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,550 | train | mutant | 3,810,618 | 225 | 3,814,563 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259I | L259I | 1 | 1 | 0 | 0 | 259 | L | I | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,304 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.03388 | 0.060116 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183290,"numValue":0.0338804893111294,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183291,"numValue":0.0601160666153916,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13551 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,551 | train | mutant | 3,810,619 | 225 | 3,814,564 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259K | L259K | 1 | 1 | 0 | 0 | 259 | L | K | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,863,886 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.121931 | 0.08716 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9720454,"numValue":-0.121930975164793,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9720455,"numValue":0.087160118860872,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13552 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,552 | train | mutant | 3,810,619 | 225 | 3,814,564 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259K | L259K | 1 | 1 | 0 | 0 | 259 | L | K | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,305 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.045932 | 0.074573 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183292,"numValue":0.0459320132920211,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183293,"numValue":0.0745730098545477,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13553 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,553 | train | mutant | 3,810,620 | 225 | 3,814,565 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259M | L259M | 1 | 1 | 0 | 0 | 259 | L | M | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,863,887 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.054538 | 0.071183 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9720456,"numValue":-0.0545384427786485,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9720457,"numValue":0.0711828556330649,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13554 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,554 | train | mutant | 3,810,620 | 225 | 3,814,565 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259M | L259M | 1 | 1 | 0 | 0 | 259 | L | M | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,566 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.169092 | 0.087414 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183814,"numValue":-0.169092127372196,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183815,"numValue":0.087414129062377,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13555 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,555 | train | mutant | 3,810,621 | 225 | 3,814,566 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259N | L259N | 1 | 1 | 0 | 0 | 259 | L | N | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,863,888 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.014362 | 0.116755 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9720458,"numValue":-0.0143621108092326,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9720459,"numValue":0.116754853071467,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13556 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,556 | train | mutant | 3,810,621 | 225 | 3,814,566 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259N | L259N | 1 | 1 | 0 | 0 | 259 | L | N | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,567 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.111246 | 0.059594 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183816,"numValue":-0.111246244506301,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183817,"numValue":0.0595937516882308,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13557 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,557 | train | mutant | 3,810,622 | 225 | 3,814,567 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259P | L259P | 1 | 1 | 0 | 0 | 259 | L | P | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,863,889 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.696491 | 0.164361 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9720460,"numValue":0.696490868852961,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9720461,"numValue":0.164361380389577,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13558 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,558 | train | mutant | 3,810,622 | 225 | 3,814,567 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259P | L259P | 1 | 1 | 0 | 0 | 259 | L | P | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,568 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.747395 | 0.058943 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183818,"numValue":-0.747394762042138,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183819,"numValue":0.0589431874123813,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13559 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,559 | train | mutant | 3,810,623 | 225 | 3,814,568 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259Q | L259Q | 1 | 1 | 0 | 0 | 259 | L | Q | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,863,890 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.016078 | 0.097211 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9720462,"numValue":-0.0160779004501453,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9720463,"numValue":0.0972107990922235,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13560 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,560 | train | mutant | 3,810,623 | 225 | 3,814,568 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259Q | L259Q | 1 | 1 | 0 | 0 | 259 | L | Q | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,569 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.21817 | 0.090621 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183820,"numValue":-0.218169504080067,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183821,"numValue":0.0906210789007888,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13561 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,561 | train | mutant | 3,810,624 | 225 | 3,814,569 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259R | L259R | 1 | 1 | 0 | 0 | 259 | L | R | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,863,891 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.014658 | 0.063608 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9720464,"numValue":0.014658050049318,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9720465,"numValue":0.0636077590232782,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13562 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,562 | train | mutant | 3,810,624 | 225 | 3,814,569 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259R | L259R | 1 | 1 | 0 | 0 | 259 | L | R | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,570 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.047133 | 0.054644 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183822,"numValue":-0.0471327098249118,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183823,"numValue":0.0546442800657207,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13563 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,563 | train | mutant | 3,810,625 | 225 | 3,814,570 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259S | L259S | 1 | 1 | 0 | 0 | 259 | L | S | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,863,892 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.037473 | 0.069978 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9720466,"numValue":-0.0374729139045294,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9720467,"numValue":0.06997826522719,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13564 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,564 | train | mutant | 3,810,625 | 225 | 3,814,570 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259S | L259S | 1 | 1 | 0 | 0 | 259 | L | S | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,571 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.100955 | 0.049548 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183824,"numValue":-0.100954787278726,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183825,"numValue":0.049548186607481,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13565 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,565 | train | mutant | 3,810,626 | 225 | 3,814,571 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259T | L259T | 1 | 1 | 0 | 0 | 259 | L | T | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,863,893 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.038564 | 0.080343 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9720468,"numValue":-0.0385636034053125,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9720469,"numValue":0.080342921259161,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13566 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,566 | train | mutant | 3,810,626 | 225 | 3,814,571 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259T | L259T | 1 | 1 | 0 | 0 | 259 | L | T | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,572 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.16632 | 0.05411 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183826,"numValue":-0.166319942666701,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183827,"numValue":0.0541099183887203,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13567 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,567 | train | mutant | 3,810,627 | 225 | 3,814,572 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259V | L259V | 1 | 1 | 0 | 0 | 259 | L | V | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,863,894 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.137178 | 0.105523 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9720470,"numValue":-0.137177548670092,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9720471,"numValue":0.105523287595935,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13568 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,568 | train | mutant | 3,810,627 | 225 | 3,814,572 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259V | L259V | 1 | 1 | 0 | 0 | 259 | L | V | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,573 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.084856 | 0.061101 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183828,"numValue":-0.0848563828695487,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183829,"numValue":0.0611014891608911,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13569 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,569 | train | mutant | 3,810,628 | 225 | 3,814,573 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259W | L259W | 1 | 1 | 0 | 0 | 259 | L | W | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,863,895 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.145259 | 0.052582 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9720472,"numValue":0.145259415410368,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9720473,"numValue":0.0525823978468502,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13570 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,570 | train | mutant | 3,810,628 | 225 | 3,814,573 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259W | L259W | 1 | 1 | 0 | 0 | 259 | L | W | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,574 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.26053 | 0.104141 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183830,"numValue":-0.26053045969176,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183831,"numValue":0.104140730895489,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13571 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,571 | train | mutant | 3,810,629 | 225 | 3,814,574 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259Y | L259Y | 1 | 1 | 0 | 0 | 259 | L | Y | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,863,896 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.014424 | 0.125281 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9720474,"numValue":-0.0144241632841425,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9720475,"numValue":0.125281014361806,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13572 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,572 | train | mutant | 3,810,629 | 225 | 3,814,574 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L259Y | L259Y | 1 | 1 | 0 | 0 | 259 | L | Y | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,575 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.021312 | 0.05601 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183832,"numValue":0.0213117666911528,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183833,"numValue":0.0560098038264368,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13573 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,573 | train | mutant | 4,906,064 | 225 | 4,912,652 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delL259 | delL259 | 1 | 0 | 1 | 0 | 259 | L | - | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,296 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.929613 | 0.094957 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183274,"numValue":-0.929612913460179,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183275,"numValue":0.0949571131528336,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16923,"numValue":6.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13574 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,574 | train | mutant | 3,811,921 | 225 | 3,815,866 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260A | D260A | 1 | 1 | 0 | 0 | 260 | D | A | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,865,189 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.284163 | 0.085532 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9723060,"numValue":0.28416306579304,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9723061,"numValue":0.085531729766279,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13576 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,576 | train | mutant | 3,811,922 | 225 | 3,815,867 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260C | D260C | 1 | 1 | 0 | 0 | 260 | D | C | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,865,190 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.414538 | 0.089123 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9723062,"numValue":0.414538473116214,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9723063,"numValue":0.0891228670893669,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13577 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,577 | train | mutant | 3,811,922 | 225 | 3,815,867 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260C | D260C | 1 | 1 | 0 | 0 | 260 | D | C | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,308 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.312573 | 0.048984 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183298,"numValue":-0.312573373827122,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183299,"numValue":0.0489844003063678,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13578 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,578 | train | mutant | 3,811,923 | 225 | 3,815,868 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260E | D260E | 1 | 1 | 0 | 0 | 260 | D | E | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,865,191 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.404395 | 0.109555 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9723064,"numValue":0.404394608396119,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9723065,"numValue":0.109555206342967,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13579 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,579 | train | mutant | 3,811,923 | 225 | 3,815,868 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260E | D260E | 1 | 1 | 0 | 0 | 260 | D | E | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,549 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.362753 | 0.049868 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183780,"numValue":-0.362752781481351,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183781,"numValue":0.0498675687024691,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13580 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,580 | train | mutant | 3,811,924 | 225 | 3,815,869 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260F | D260F | 1 | 1 | 0 | 0 | 260 | D | F | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,865,192 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.5913 | 0.130586 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9723066,"numValue":0.591299748344266,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9723067,"numValue":0.130586026098179,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13581 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,581 | train | mutant | 3,811,924 | 225 | 3,815,869 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260F | D260F | 1 | 1 | 0 | 0 | 260 | D | F | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,550 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.673551 | 0.067317 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183782,"numValue":-0.673551368286198,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183783,"numValue":0.0673169675690554,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13582 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,582 | train | mutant | 3,811,925 | 225 | 3,815,870 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260G | D260G | 1 | 1 | 0 | 0 | 260 | D | G | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,865,193 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.587979 | 0.08379 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9723068,"numValue":0.587978820157081,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9723069,"numValue":0.0837897796013436,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13584 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,584 | train | mutant | 3,811,926 | 225 | 3,815,871 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260H | D260H | 1 | 1 | 0 | 0 | 260 | D | H | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,865,194 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.089335 | 0.092152 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9723070,"numValue":0.0893346449034182,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9723071,"numValue":0.0921518524706145,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13585 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,585 | train | mutant | 3,811,926 | 225 | 3,815,871 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260H | D260H | 1 | 1 | 0 | 0 | 260 | D | H | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,552 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.192177 | 0.063607 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183786,"numValue":-0.192176691860089,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183787,"numValue":0.0636073404379637,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13586 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,586 | train | mutant | 3,811,927 | 225 | 3,815,872 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260I | D260I | 1 | 1 | 0 | 0 | 260 | D | I | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,865,195 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.529254 | 0.118783 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9723072,"numValue":0.529254205163014,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9723073,"numValue":0.118783430216657,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13587 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,587 | train | mutant | 3,811,927 | 225 | 3,815,872 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260I | D260I | 1 | 1 | 0 | 0 | 260 | D | I | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,553 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.542947 | 0.061241 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183788,"numValue":-0.542947015271121,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183789,"numValue":0.0612412601038782,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13588 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,588 | train | mutant | 3,811,928 | 225 | 3,815,873 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260K | D260K | 1 | 1 | 0 | 0 | 260 | D | K | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,865,196 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.234545 | 0.10829 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9723074,"numValue":0.234545436937882,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9723075,"numValue":0.108290064586539,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13589 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,589 | train | mutant | 3,811,928 | 225 | 3,815,873 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260K | D260K | 1 | 1 | 0 | 0 | 260 | D | K | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,554 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.206285 | 0.049139 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183790,"numValue":-0.20628507504411,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183791,"numValue":0.0491394246307569,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13590 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,590 | train | mutant | 3,811,929 | 225 | 3,815,874 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260L | D260L | 1 | 1 | 0 | 0 | 260 | D | L | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,865,197 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.490819 | 0.061881 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9723076,"numValue":0.490818658693084,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9723077,"numValue":0.0618811824422725,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13592 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,592 | train | mutant | 3,811,930 | 225 | 3,815,875 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260M | D260M | 1 | 1 | 0 | 0 | 260 | D | M | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,865,198 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.346596 | 0.086276 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9723078,"numValue":0.346596493206511,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9723079,"numValue":0.0862755132541662,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13593 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,593 | train | mutant | 3,811,930 | 225 | 3,815,875 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260M | D260M | 1 | 1 | 0 | 0 | 260 | D | M | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,556 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.337377 | 0.046984 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183794,"numValue":-0.337376629177205,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183795,"numValue":0.0469842101602774,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13594 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,594 | train | mutant | 3,811,931 | 225 | 3,815,876 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260N | D260N | 1 | 1 | 0 | 0 | 260 | D | N | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,865,199 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.263181 | 0.05941 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9723080,"numValue":0.263181218250728,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9723081,"numValue":0.0594099919162765,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13595 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,595 | train | mutant | 3,811,931 | 225 | 3,815,876 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260N | D260N | 1 | 1 | 0 | 0 | 260 | D | N | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,557 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.033778 | 0.051199 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183796,"numValue":-0.0337778452735263,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183797,"numValue":0.0511987902580608,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13596 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,596 | train | mutant | 3,811,932 | 225 | 3,815,877 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260P | D260P | 1 | 1 | 0 | 0 | 260 | D | P | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,865,200 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.24471 | 0.096712 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9723082,"numValue":0.244710018074325,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9723083,"numValue":0.0967124348080203,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13597 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,597 | train | mutant | 3,811,932 | 225 | 3,815,877 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260P | D260P | 1 | 1 | 0 | 0 | 260 | D | P | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,558 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.372683 | 0.052376 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183798,"numValue":-0.372682995351781,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183799,"numValue":0.0523759025330094,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13598 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,598 | train | mutant | 3,811,933 | 225 | 3,815,878 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260Q | D260Q | 1 | 1 | 0 | 0 | 260 | D | Q | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,865,201 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.277754 | 0.078025 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9723084,"numValue":0.277753759913101,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9723085,"numValue":0.0780253270376643,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13599 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,599 | train | mutant | 3,811,933 | 225 | 3,815,878 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260Q | D260Q | 1 | 1 | 0 | 0 | 260 | D | Q | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,559 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.347458 | 0.051138 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183800,"numValue":-0.34745802418829,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183801,"numValue":0.0511382223189728,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13600 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,600 | train | mutant | 3,811,934 | 225 | 3,815,879 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260R | D260R | 1 | 1 | 0 | 0 | 260 | D | R | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,865,202 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.176553 | 0.078058 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9723086,"numValue":0.176553435896196,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9723087,"numValue":0.0780580389454989,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13601 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,601 | train | mutant | 3,811,934 | 225 | 3,815,879 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260R | D260R | 1 | 1 | 0 | 0 | 260 | D | R | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,560 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.089018 | 0.041327 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183802,"numValue":-0.089017842688647,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183803,"numValue":0.0413273858513461,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13602 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,602 | train | mutant | 3,811,935 | 225 | 3,815,880 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260S | D260S | 1 | 1 | 0 | 0 | 260 | D | S | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,865,203 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.36006 | 0.07894 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9723088,"numValue":0.360059913271426,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9723089,"numValue":0.0789400001427306,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13603 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,603 | train | mutant | 3,811,935 | 225 | 3,815,880 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260S | D260S | 1 | 1 | 0 | 0 | 260 | D | S | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,561 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.346171 | 0.044032 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183804,"numValue":-0.34617139311229,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183805,"numValue":0.044032390432075,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13604 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,604 | train | mutant | 3,811,936 | 225 | 3,815,881 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260T | D260T | 1 | 1 | 0 | 0 | 260 | D | T | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,865,204 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.450123 | 0.068357 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9723090,"numValue":0.450122524718235,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9723091,"numValue":0.0683572726021599,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13605 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,605 | train | mutant | 3,811,936 | 225 | 3,815,881 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D260T | D260T | 1 | 1 | 0 | 0 | 260 | D | T | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,562 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.483483 | 0.048406 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183806,"numValue":-0.483483096355105,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183807,"numValue":0.048406291581403,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16924,"numValue":8.0,"position":260,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] |
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